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---
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datasets:
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- EleutherAI/pile
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- Open-Orca/OpenOrca
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- GAIR/lima
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- WizardLM/WizardLM_evol_instruct_V2_196k
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language:
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- en
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license: llama3
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tags:
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- biology
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- medical
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---
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# Instruction Pre-Training: Language Models are Supervised Multitask Learners
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This repo contains the **biomedicine model developed from Llama3-8B** in our paper [Instruction Pre-Training: Language Models are Supervised Multitask Learners](https://huggingface.co/papers/2406.14491).
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We explore supervised multitask pre-training by proposing ***Instruction Pre-Training***, a framework that scalably augments massive raw corpora with instruction-response pairs to pre-train language models. The instruction-response pairs are generated by an efficient instruction synthesizer built on open-source models. ***Instruction Pre-Training* outperforms *Vanilla Pre-training* in both general pre-training from scratch and domain-adaptive continual pre-training.** In pre-training from scratch, *Instruction Pre-Training* not only improves pre-trained base models but also benefits more from further instruction tuning. **In continual pre-training, *Instruction Pre-Training* enables Llama3-8B to be comparable to or even outperform Llama3-70B.**
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<p align='center'>
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<img src="https://cdn-uploads.huggingface.co/production/uploads/66711d2ee12fa6cc5f5dfc89/vRdsFIVQptbNaGiZ18Lih.png" width="400">
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</p>
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## Resources
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**🤗 We share our data and models with example usages, feel free to open any issues or discussions! 🤗**
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- Context-Based Instruction Synthesizer: [instruction-synthesizer](https://huggingface.co/instruction-pretrain/instruction-synthesizer)
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- Fine-Tuning Data for the Synthesizer: [ft-instruction-synthesizer-collection](https://huggingface.co/datasets/instruction-pretrain/ft-instruction-synthesizer-collection)
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- General Models Pre-Trained from Scratch:
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- [InstructLM-500M](https://huggingface.co/instruction-pretrain/InstructLM-500M)
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- [InstructLM-1.3B](https://huggingface.co/instruction-pretrain/InstructLM-1.3B)
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- Domain-Specific Models Pre-Trained from Llama3-8B:
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- [Finance-Llama3-8B](https://huggingface.co/instruction-pretrain/finance-Llama3-8B)
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- [Biomedicine-Llama3-8B](https://huggingface.co/instruction-pretrain/medicine-Llama3-8B)
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- General Instruction-Augmented Corpora: [general-instruction-augmented-corpora](https://huggingface.co/datasets/instruction-pretrain/general-instruction-augmented-corpora)
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- Domain-Specific Instruction-Augmented Corpora (no finance data to avoid ethical issues): [medicine-instruction-augmented-corpora](https://huggingface.co/datasets/instruction-pretrain/medicine-instruction-augmented-corpora)
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## Domain-Adaptive Continued Pre-Training
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Following [AdaptLLM](https://huggingface.co/AdaptLLM/medicine-chat), we augment the domain-specific raw corpora with instruction-response pairs generated by our [context-based instruction synthesizer](https://huggingface.co/instruction-pretrain/instruction-synthesizer).
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### 1. To chat with the biomedicine-Llama3-8B model:
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```python
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from transformers import AutoModelForCausalLM, AutoTokenizer
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model = AutoModelForCausalLM.from_pretrained("instruction-pretrain/medicine-Llama3-8B")
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tokenizer = AutoTokenizer.from_pretrained("instruction-pretrain/medicine-Llama3-8B")
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# Put your input here, NO prompt template is required
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user_input = '''Question: Which of the following is an example of monosomy?
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Options:
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- 46,XX
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- 47,XXX
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- 69,XYY
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- 45,X
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Please provide your choice first and then provide explanations if possible.'''
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inputs = tokenizer(user_input, return_tensors="pt", add_special_tokens=True).input_ids.to(model.device)
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outputs = model.generate(input_ids=inputs, max_new_tokens=400)[0]
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answer_start = int(inputs.shape[-1])
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pred = tokenizer.decode(outputs[answer_start:], skip_special_tokens=True)
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print(pred)
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```
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### 2. To evaluate our models on the domain-specific tasks
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1. Setup dependencies
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```bash
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git clone https://github.com/microsoft/LMOps
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cd LMOps/adaptllm
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pip install -r requirements.txt
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```
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2. Evaluate
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```bash
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DOMAIN='biomedicine'
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# if the model can fit on a single GPU: set MODEL_PARALLEL=False
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# elif the model is too large to fit on a single GPU: set MODEL_PARALLEL=True
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MODEL_PARALLEL=False
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# number of GPUs, chosen from [1,2,4,8]
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N_GPU=1
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# Set as True
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add_bos_token=True
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bash scripts/inference.sh ${DOMAIN} 'instruction-pretrain/medicine-Llama3-8B' ${add_bos_token} ${MODEL_PARALLEL} ${N_GPU}
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```
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## Citation
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If you find our work helpful, please cite us:
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[AdaptLLM](https://huggingface.co/papers/2309.09530)
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```bibtex
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@inproceedings{
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cheng2024adapting,
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title={Adapting Large Language Models via Reading Comprehension},
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author={Daixuan Cheng and Shaohan Huang and Furu Wei},
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booktitle={The Twelfth International Conference on Learning Representations},
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year={2024},
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url={https://openreview.net/forum?id=y886UXPEZ0}
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}
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```
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