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1
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ุงู„ุณู„ุงู… ุนู„ูŠูƒู… ูˆุฑุญู…ุฉ ุงู„ู„ู‡ ูˆุจุฑูƒุงุชู‡ ุงู„ูŠูˆู… ุณู†ูƒู…ู„ ุงู„ู„ูŠ
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ู‡ูˆ solutions of contact lenses ู‡ุชูƒู„ู… ุงู„ูŠูˆู… ุดูˆูŠุฉ
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ุนู„ู‰ enzymatic cleaners ูˆู‡ุฐู‡ ุฃุญุฏุซ ุตุญูŠุญุฉ ููŠ ุนุงู„ู…
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ุชู†ุธูŠู ุงู„ุนุฏุณุงุช ุงู„ู„ุณุงู†ูŠุฉ ุจูŠู‚ูˆู„ in form of tablets
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containing N-enzyme are dissolved in either saline
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or distilled water to remove the natured protein
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deposited from the surfaces of the contaminant
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ูŠุจู‚ู‰ ุงุญู†ุง ู†ุฌูŠุจ ุงู„ู‚ุฑุต ุจุชุงุน ุงู„ุงู†ุฒูŠู† ูˆู†ุญุทู‡ ุงู…ุง ููŠู‡
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saline ุงูˆ ููŠู‡ distilled water ู…ุงุก ู…ู‚ุทุฑ ุชู„ู‚ุงุนุจ
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ุงู„ู…ุญู„ูˆู„ ู‡ู†ุง ุจุฏูˆุฑ ู‡ูˆ ุงู„ N ู‡ูˆ ู…ู‡ู…ุชู‡ ู‡ุฐุง ุงู†ู‡ ูŠุดูŠู„ ุงู„
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proteinุงู„ู…ุชุฑุณุฏ ุนู„ู‰ ุณุทุญ ุงู„ contact lens ูŠุนู†ูŠ ุซุจุช ุงู†
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ุงู„ู†ุฒูŠู… ู‡ุงุถู… ูŠุนู†ูŠ ุญุชู‰ ููŠ ุงู„ู‚ู†ุงุฉ ุงู„ู‡ุถู…ูŠุฉ ู‡ูˆ ู‡ุงุถู… ูˆ
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they are originally introduced for use about once
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a week with hydrogel lenses ูŠุนู†ูŠ ู‡ู… ูƒุงู†ูˆุง ูŠุญุทูˆู‡ู…
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ุนู„ู‰ hydrogel lenses once weekly ูŠุนู†ูŠ ููŠ ุงู„ุฃุณุจูˆุน
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ูŠุนู†ูŠ ููŠ ุงู„ุดู‡ุฑ ุฃุฑุจุน ู…ุฑุฉุจู‚ู‰ ุฅูู„ุณุฑูŠ ูƒุงู† ู‚ุตู‡ ุจูŠุณุชุฎุฏู…
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ุงู„ู€ rigid contact lenses ูŠุนู†ูŠ ูƒุงู† ููŠ ุงู„ู‡ูŠุฏุฑูˆุฌูŠ ุงู„
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contact lenses ู„ูƒู† ู…ู…ูƒู† ุงุณุชุฎุฏุงู… ุงู„ rigid contact
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lenses ููŠ ุงู„ุนุงุฏู‰ ุงุณุชุนู…ุงู„ ุงู„ contact lens ุจูŠุนู…ู„
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ููŠู„ู… ุฃูˆ ุจุฑูˆุชูŠู† ุนู„ู‰ ุณุทุญ ุงู„ contact lens ูˆู‡ุฐุง
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ุงู„ุจุฑูˆุชูŠู† ุฌุงุก ุฃุณุงุณุง ู…ู† ุชููŠู„ู…ูˆุฌู‡ุฉ ุฃุณุงุณุง ู…ู† ุชูŠุฑ ููŠู„ู…
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ุงู„ู„ูŠ ู‡ูˆ ุจูŠุดูƒู„ ุฒูŠ ุงู„ circulation ูŠุนู†ูŠ ููŠ ุชุฌุฏูŠุฏ ุฃูˆ
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refreshing ู„ู„ุฅูŠุด ุงู„ู„ูŠ ู‡ูˆ ุชูŠุฑ ููŠู„ู… ูˆุจุงู„ุชุงู„ูŠ ููŠ
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protein ููŠ ุงู„ contact lens ูุจุชุฑุณุจ ุนู„ู‰ ุณุทุญ ุงู„ุนุฏุณุฉ
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ุงู„ู„ูŠ ู„ู…ุณูƒู‡ุง ุชู…ุงู…ุง ู„ูˆ ุญุทูŠู†ุง ุตุฎุฑุฉ ููŠ ู…ุฌุฑู…ุงุก ุจุนุฏ ุดูˆูŠุฉ
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ุจุชุตูŠุฑ ุฎุถุฑุฉ ูˆุตูŠุฑ ุนู„ูŠู‡ุง ุชุญุงุฑุจ ูˆุฒูŠ ูƒุฏู‡
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ู…ู…ูƒู† ุงู† ูŠูƒูˆู† ููŠู‡ fat deposits ูˆ protein deposits
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ุงูˆ another test ุงุตุนุจ ุดูŠุก ููŠ ุงู„ุฅุฒุงู„ุฉ ุงูŠุด ุงู„ู„ูŠ ู‡ูˆ ุงู„
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protein ุงู„ุดูŠุก ุงู„ุตุนุจ ุงู†ู‡ ุงุญู†ุง ู†ุฒูŠู„ู‡ ุงู„ู„ูŠ ู‡ูˆ ุงู„
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protein ููŠ ุฃูƒู…ูŠู† ููŠ grab uric ุทูŠุจ ุญูŠุจุฏุฃ ููŠ ุงู„
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papainู‡ูˆ ุงู†ุฒูŠู† one of the enzymatic ุฃูˆ enzymes
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used in protein removing tablets is a thermostable
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ูŠุนู†ูŠ ู„ูˆ ุชุนุฑุถ ุงู„ุญุฑุงุฑุฉ ุจุชูƒุณุงุด ูŠุนู†ูŠ ู…ุณุชู‚ุฑ ููŠ ุงู„ุญุฑุงุฑุฉ
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thermostable are endobotidase ูŠุนู†ูŠ ูˆุฒูŠ ุงู„ุจุฑูˆุชูŠู†ุงุช
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found in the tau tau throat ุงู„ุขู† ููŠ ุบุฒุฉ ุณู…ุน ุฃู†ุง
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ูƒุฏู‡ ุจุงุณู…ู‡ ุจุงุจุง
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ู‡ุฐุง ุฃุฎุฐูˆุง ู…ู†ู‡ ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุจุฑุจูŠุน ุจุฑุจูŠุน ุจุฑุจูŠุน
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ุงู„ุณุจุชูŠู„ุฒู… ู‡ูˆ ู†ุจุงุช ู…ู† ุจูƒุชูŠุฑูŠุง ุจุงุณูŠู„ุงุณ
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ุงู„ุฃูƒู„ูŠูƒูŠู†ูˆููˆุฑู…ุณุŒ ู„ุฃ ู‡ู†ุง ุงู„ุณุจุชูŠู„ุฒู… ุฅู†ุฒูŠู… ุจุณ ู„ุง ูŠูุฎู„
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ู…ู† ุงู„ุจุถุงุฆุนุŒ ูŠูุฎู„ ู…ู† ุฃูŠุดุŸ ุจูƒุชูŠุฑูŠุง ุงุณู…ู‡ุง ุจุงุณูŠู„ุงุณ
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ุงู„ุฃูƒู„ูŠูƒูŠู†ูˆููˆุฑู…ุณEquilibrium of the efficiency of
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papain and subtilism ูŠุนู†ูŠ ู‚ุงุฑู†ูˆุง ุจูŠู† ุงุชู†ูŠู† ูˆุฌุฏูˆุง
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ุงู†ู‡ ุทุจุนุง ุงู„ papain ุงู‚ูˆู‰ ููŠ ุงุฒุงู„ุฉ ู„ุจุฑูˆุชูŠู†ุงุช ุงู„
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heavy protein deposits ุจูŠู†ู…ุง ุงู„ subtilism ููŠ ุงู„
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light protein deposits ูŠุจู‚ู‰ ู„ูˆ ุงู„ุนุฏุณุฉ ุงู„ู„ุงุฒู‚ุฉ
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ุนู„ูŠู‡ุง ุทุจู‚ุฉ ุจุฑูˆุชูŠู†ูŠุฉ ุณู…ูŠูƒุฉ ุงู‡ ู‡ูˆ ุงู„ papainุจูŠู†ู…ุง ู„ูˆ
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ุทุจู‚ุฉ ุฑููŠุนุฉ
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ูˆุฎููŠูุฉ ุจุงู„ูุชุฑุฉ ุฅูŠู‡ ุงู„ู„ูŠ ู‡ูˆ Subtilism ุงู„ูุชุฑุฉ
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however when chemical disinfection and enzymatic
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cleaning was compared with oxidative disinfection
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alone, the lenses treated by the former method
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were significantly cleaner
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by later ูŠุนู†ูŠ ู‚ุงุฑู†ู‡ ุจูŠู† ุนุฏุณุฉ ู„ุงุณูƒุง ุจู†ุญุท ู„ู‡ุง
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hydrogen peroxide ู…ุงุก ุฃูƒุณุฌูŠู† ุจุงุณุชู…ุฑุงุฑ ูˆุจูŠู† ุนุฏุณุฉ
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ุจู†ุญุท ู„ู‡ุง ุงู„ papain ุงู†ุฒูŠู† ู…ู† ุฃู†ุถุงู ู„ุฌูˆ ุงู„ู„ูŠ ุจู†ุญุท
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ู„ู‡ุง ุงู„ papain ู…ุง ู…ู„ุงุญุธุฉ ุงู† ุงู„ papain once weekly
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ูู„ู…ุง ุงู„ hydrogen ุงู„ hydrogen peroxide daily ูƒู„ ูŠูˆู…
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ูู…ุด ู…ู‚ู„ูˆู„ ูŠุญุทูˆุง ูƒู„ ูŠูˆู… ุงู†ุฒูŠุจ ู…ูƒู„ู ูู‡ู… ุงู„ุฃู† ูˆุฌุฏูˆุง
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ุฃูุถู„ ุทุฑูŠู‚ุฉ ุงู„ุฌู…ุน ุจูŠู† ุงู„ุญุณู†ุงุฌูŠู† ูƒูŠู ุงู„ุฌู…ุนุฉ ุจูŠู†
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ุงู„ุญุณู†ุงุฌูŠู† ุงู†ู‡ ูƒู„ ูŠูˆู… ูŠุญุทูˆุง hydrogen peroxide ู…ุญู„ูˆู„
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ููŠ ุงู„ูƒุงุณ ูˆููŠ ุขุฎุฑ ุงู„ุณุจูˆุน ูŠูˆู… ุงู„ุฌู…ุนุฉ ู…ุซู„ุง ูŠุญุทูˆุง ุงุด
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ุจุงุจูŠุฏ ู‡ูŠูƒ ูŠู‚ูˆู„ูƒ ุงู† ู‡ูŠูƒ ุฃูุถู„
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with either type of cleaner were contaminated more
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than those treated with both ุจุณ ูƒุงู† ุงุญู†ุง ุฌุงู…ุนู†ุง
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ุจูŠู† ุงู„ู„ูŠ ู‡ูˆ ุงู„ุจุฑุชูŠู† ูƒุฅู†ุฒูŠู† ูˆุงู„ู‡ูŠุฏุฑูˆุฌูŠู†
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00:06:40,190 --> 00:06:46,690
ุงู„ู‡ูŠู„ูŠุจุฑูˆุฅูƒุณุงูŠุฏ ูƒdisinfectant ู‡ุฐุง ูƒู„ ูŠูˆู… ูˆ ู‡ุฐุง ู…ุฑุฉ
75
00:06:46,690 --> 00:06:51,350
ููŠ ุงู„ุฃุณุจูˆุน ูˆุฌุฏูˆุง ุงู†ู‡ ุงู„ู†ุธุงูุฉ ูˆ ุงู„ุทู‡ุงุฑุฉ ูˆ ุงู„ุชุทู‡ูŠุฑ
76
00:06:51,350 --> 00:06:55,090
ุฃูุถู„ ุจุงู„ุชุงู†ูŠู† ู…ู† ูˆุงุญุฏ ูˆุงุถุญ ุจุงู„ู†ุณุจุงู„ูŠุŸ
77
00:07:00,490 --> 00:07:04,350
ูˆ ู‚ุจู„ ูุชุฑุฉ ุญุฏ ุงู„ุณู†ูˆุงุช ุทู„ุนูˆุง ู…ุญู„ูˆู„ ุงุณู…ู‡ comfort
78
00:07:04,350 --> 00:07:09,950
drops ูˆ ูƒู„ู…ุฉ comfort ุชุดูŠ ุจุฑุงู‡ุง comfort ูŠุนู†ูŠ ุฑุงุญุฉ ูˆ
79
00:07:09,950 --> 00:07:14,570
comfort ูŠุนู†ูŠ ู…ุฑูŠุถ these drops which are also
80
00:07:14,570 --> 00:07:18,470
referred to as re-wetting condition ุงูˆ
81
00:07:18,470 --> 00:07:24,070
conditioning ุงูˆ cushioning drops ูŠุนู†ูŠ ู†ูˆุน ู…ู†
82
00:07:24,070 --> 00:07:29,130
ุงู„ุชุฑุชูŠุจ ูˆ ู†ูˆุน ู…ู† ุงู„ุฑุงุญุฉ cushioning ุฒูŠ ุงู„ูˆุณุงุฏุฉ
83
00:07:34,720 --> 00:07:40,640
ูˆุทุฑูŠู‚ุฉ ูŠุนู†ูŠ Can be installed into the eyes of
84
00:07:40,640 --> 00:07:44,220
contact lens wearers at any time during wear to
85
00:07:44,220 --> 00:07:47,800
enhance comfort ูŠุนู†ูŠ ุฃู†ุง ูˆุงู†ุง ุดูˆููˆุงุŒ ูˆุงู„ูˆุงุญุฏ ู„ู ุงู„
86
00:07:47,800 --> 00:07:52,200
contact lensุŒ ุจูŠุญุทู‡ุง ูƒู„ ุดูˆูŠุฉ ุชุนู…ู„ comfortุŒ ุนุดุงู† ู‡ูŠ
87
00:07:52,200 --> 00:07:55,960
ุชุณู…ูŠู‡ุง comfort The eye can tolerate adverse
88
00:07:55,960 --> 00:08:00,140
atmospheric conditions and while it can also
89
00:08:00,140 --> 00:08:02,460
tolerate the wearing of contact lenses
90
00:08:05,370 --> 00:08:11,310
in coping with both ูŠุนู†ูŠ ุจู‚ูˆู„ ุงู„ู„ูŠ ุจุฏูƒ ุชุนุฑู ุงู†ู‡
91
00:08:11,310 --> 00:08:16,230
ุนุงู…ู„ ุงู„ุทุจูŠุนุฉ ุงุญู†ุง ู…ุงุชุนุทู„ู‚ูˆุง ู…ู† ุงู„ุถูˆุก ูˆ ู…ู† ุงู„ุบุจุงุฑ ูˆ
92
00:08:16,230 --> 00:08:20,910
ู…ู† ุงู„ุฅุฌู‡ุงุฏ ู‡ุฐุง ุนุงู…ู„ ุฅุฌู‡ุงุฏ ูŠุนู†ูŠ ุทูŠุจ ูˆุถุน ุงู„
93
00:08:20,910 --> 00:08:23,490
contactless ุนุงู…ู„ ุฅุฌู‡ุงุฏ ูŠุง ุฃุฎูŠ
94
00:08:32,420 --> 00:08:35,200
ู‡ูŠ ุจู†ุนู…ู„ ุงู„ุดูƒู„ ูŠุนู†ูŠ ู‡ูŠ ุจู‚ู‰ ู†ุนู…ู„ foreign body ููŠ
95
00:08:35,200 --> 00:08:39,020
ุงู„ุนูŠู† ู…ู‡ู…ุง ุฒูŠู‘ู†ู‡ุง ุฃูˆ ู…ู‡ู…ุง .. ู…ู‡ู…ุง ุฎู„ู‘ูŠู†ู‡ุง smooth
96
00:08:39,020 --> 00:08:45,040
ุจูŠูุถู„ ุฃู†ู‡ ููŠ ุฅุฌู‡ุงุฏ ุนู„ูŠู‡ ููŠ ุงู„contact lens ูุจู‚ูˆู„ู‘ูŠ
97
00:08:45,040 --> 00:08:52,320
ุฅู† ูƒุงู†ุช ุงู„ุนูˆุงู…ู„ ุงู„ุฌูˆูŠุฉ ุตุนุจุฉ ูˆ ุงู„ุนุฏุณุฉ ู…ุซู„ุง hard ุฑุฌู„
98
00:08:52,320 --> 00:08:57,820
ูู…ู…ูƒู† ุงู„ุนูŠู† ู…ุง ุชุชุญู…ู„ ุงู„ .. ุงู„ .. ุฅูŠุด ุงู„ุฌู‡ุฏูŠู† ู…ุน
99
00:08:57,820 --> 00:09:03,010
ุจุนุถ ูŠุนู†ูŠ ุฌู‡ุฏ ูˆุงุญุฏ ู„ุญุงู„ู‡ ูŠูƒููŠููƒูŠู ูŠูƒูˆู† ุงู„ุฌูˆ ู…ุบูุฑ
100
00:09:03,010 --> 00:09:08,130
ูˆู‚ุฑุงุกุฉ ูƒุซูŠุฑุฉ ูˆููŠู‡ ุถูˆุก ูƒุซูŠุฑ ูˆุณุงุทุฉ ูˆุดูŠุก ูŠุนู†ูŠ ู…ู…ูƒู†
101
00:09:08,130 --> 00:09:11,150
ุงู„ุนูŠู† ู…ุง ุชุชุญู…ู„ ูุจู‚ูˆู„ ุงู„ factors that reduce
102
00:09:11,150 --> 00:09:15,590
contact lens tolerance ู…ุง ู‡ูŠ ุงู„ุฃูˆุงู…ู„ ุงู„ุชูŠ ุชุคุซุฑ ุนู„ู‰
103
00:09:15,590 --> 00:09:21,850
ุนุฏู… ุชุญู…ู„ ุงู„ุนุฏุณุฉ ุงู„ุฃุฎุฑู‰ ููŠู‡ุง ุนูˆุงู…ู„ ุฃูˆู„ ุนุงู…ู„ ุงู†ู‡ุง in
104
00:09:21,850 --> 00:09:28,230
particular ูŠุนู†ูŠ ุนู† ุฎุตูˆุต ุงู„ dry smoky environment
105
00:09:28,230 --> 00:09:30,970
ูŠูƒูˆู† ุงู„ุฌูˆ ุฌุงู
106
00:09:34,370 --> 00:09:38,510
ุณูˆุงุก ู…ู† ุงู„ุชู†ุฎูŠู† ุฃูˆ ุฃุจุฎุฑุฉ ุฃูˆ ุญุงุฌุฉ ู‡ุฐุง ุงู„ุฌูˆ ุบูŠุฑ
107
00:09:38,510 --> 00:09:41,930
ู…ู†ุงุณุจ ู„ู„ู†ุงุณ ุงู„ู„ูŠ ุนู†ุฏู‡ุง ุณู„ุณู„ุฉ ู‚ุฏ ุชุฌุนู„ ุงู„ุชุบูŠูŠุฑ ููŠ
108
00:09:41,930 --> 00:09:47,850
ุงู„ู€ Lens ุชุนู…ู„ ุงุถุทุฑุงุจ ููŠ ุงู„ุธู„ุงูุฉ ู…ุง ุจูŠู† ุงู„ contact
109
00:09:47,850 --> 00:09:52,850
lens ูˆ ู…ู† ุงู„ุชูŠุฑ film which turns an acceptable
110
00:09:52,850 --> 00:09:58,090
situation into an intolerant terrible one ูŠู‚ู„
111
00:09:58,090 --> 00:10:01,390
ุงู„ุชุญู…ู„ ุจุงู„ุนูŠู† ู„ู„ุนุฏุณุฉ ุงู„ู„ุงุตูุฉ ุชู„ุงู‚ูŠ ุงู„ูˆุงุญุฏ ุจุงู„ูƒุฑู‡
112
00:10:06,280 --> 00:10:11,880
ูˆุจุฑุฏ ูƒุฐู„ูƒ ุชุงู„ูŠ certain drugs such as
113
00:10:11,880 --> 00:10:15,960
antihistamines which have an anti-masculinic
114
00:10:15,960 --> 00:10:18,380
effect can induce contact lenses ู„ู†ุง ุงู„
115
00:10:18,380 --> 00:10:21,920
antihistamines ู†ุงุฎุฏู‡ุง ุฃูŠุงู… ุงู„ุญุณุงุณูŠุฉ ูˆุงู„ูˆุงุฌู‡ุฉ
116
00:10:21,920 --> 00:10:27,080
ูุงูƒุฑูŠู† ูƒู… ุณู†ุฉ ุชุฏูŠูƒู† ุฌูŠูƒุณ ู…ุซู„ุง ุงูˆ ุจุงู„ู‡ูŠุณู…ุงู†ุงู„
117
00:10:27,080 --> 00:10:33,670
ู‡ุณุชุงู†ูŠู„ ููŠ ุญุงุฌุงุช ุฒูŠ ู‡ุฐู‡ ู†ุงุฎุฏู‡ุง ุงู„ุงุญุชู‚ุงู†ุงุชุญุชู‰ ููŠู†ุง
118
00:10:33,670 --> 00:10:37,470
ู†ุงุณ ู…ู†ุงู‚ุด ุจุฑูˆุฒูˆู„ูŠู† ูˆูƒู„ุงู… ููŠ ุฃู†ูู‡ุŒ ูู‡ุฐู‡ ูƒู„ู‡ุง
119
00:10:37,470 --> 00:10:45,410
ุฃู†ุชูŠุณุชุงู…ูŠู† ูุจู‚ูˆู„ ู„ูˆ ุงุญู†ุง ุจู†ุงุฎุฏ ู‚ุทุฑุฉ ุฃู†ุชูŠุณุชุงู…ูŠู† ุฃูˆ
120
00:10:45,410 --> 00:10:50,670
ุฃู‚ู„ุงุต ุฃู†ุชูŠุณุชุงู…ูŠู† ู…ู…ูƒู† ุชุฃุซุฑ ุนู„ู‰ ุชุญู…ู„ ุงู„ุนู†ุตุฑ ู„ุฃู†ู‡ุง
121
00:10:50,670 --> 00:10:55,450
ุจุชุฌูู ููŠ ุงู„ุฅูุฑุงุฒ ุชู…ุงู…ุง ุจุชุฌูู ููŠ ุฅูุฑุงุฒ ุงู„ุบุฏู„
122
00:11:02,240 --> 00:11:06,560
ุงู„ู„ูŠ .. ุงู„ู„ูŠ ู‡ูˆ ุงู„ cells ูˆ ุงู„ glance ุงู„ู„ูŠ ููŠ ุงู„ุนูŠู†
123
00:11:06,560 --> 00:11:12,180
ุฎุงุตุฉ ุงู„ wall frank ูˆ ุงู„ cross accessory ู„ูƒุฑูŠู…ุงู„
124
00:11:12,180 --> 00:11:16,280
glance wall frank and cross ูŠุนู†ูŠ ุงู„ูˆุงุญุฏ ุจูŠุงุฎุฏ
125
00:11:16,280 --> 00:11:21,300
ุงู„ุญู‚ู†ุฉ ุจุชุงุนุฉ ุงู„ุฑุดุญ ุฃูˆุดูŠ ุฃูˆ ุงู„ุญุณูŠุฉ ุฃูˆ ุงู„ุดุฑุงุจ ุฃูˆ
126
00:11:21,300 --> 00:11:25,640
ุงู„ุฃู‚ุงุต ุฃูˆ ุญุชู‰ ููŠ ุงู„ุนูŠู† ู‚ุงุทุฑุฉ ู„ุฃ ูŠุนู†ูŠ ุงู„ู„ูŠ ุจู„ุจุณ
127
00:11:25,640 --> 00:11:29,080
contact lens ู…ุด ู„ุงุฒู… .. ู„ุงุฒู… ูŠุญุท ู‚ุงุทุฑุฉ ุญุณูŠุฉ ู‚ุงุทุฑุงุช
128
00:11:29,080 --> 00:11:32,120
ุงู„ุญุณูŠุฉ ุจุชุงุนุฉ ุงู„ุนูŠู† ุนุงุฑููŠู†ู‡ุงุŸุงู„ูˆู‚ุช ููŠู†ุง ุชู„ุงู‚ูŠ ููŠ
129
00:11:32,120 --> 00:11:35,460
ุงู„ุฑุจูŠุน ุงู„ุขู† ูŠุดู‚ ุดูˆูŠู‡ ูˆุนูŠู†ู‡ ุญู…ุฑู‡ ูˆุดุบู„ู‡ ูˆุญุงุณ ููŠู‡ุง
130
00:11:35,460 --> 00:11:38,900
ุฑู…ู„ ุจูˆุดูŠ ููŠุฑูˆุญ ูŠู‚ูˆู„ูˆุง ู„ู„ุฏูƒุชูˆุฑ ูŠู‚ูˆู„ูˆุง ู…ุนุงูŠุง ุญุงุณูŠุฉ
131
00:11:38,900 --> 00:11:43,300
ูŠุนู†ูŠ ุงูˆ ู‡ูŠ ูŠู‚ูˆู„ูˆุง ุงู‡ ู…ุนุงูƒ ุญุงุณูŠุฉ ุฎุฏ ู…ุซู„ุง ู‚ุทุฑุฉ ุฒูŠ
132
00:11:43,300 --> 00:11:50,140
ู…ุซู„ุง ูƒูˆู„ูŠู‡ูŠุณุช ุงู†ุชุณุชูŠู„ ุจุฑุงูŠููŠู„ ู…ุซู„ุง ุงูˆ ูŠู‚ูˆู„ูˆุง ู…ุซู„ุง
133
00:11:50,140 --> 00:11:54,040
ูŠู‚ูˆู„ูˆุง ูƒุฑุงูŠุฒูŠู† ุงูƒุชูŠุฑ ุงุณุงู…ูŠ ูŠุนู†ูŠ ูˆ ู‡ูˆ ุจู„ุจุณ
134
00:11:54,040 --> 00:11:56,300
contactless ุจุฌู„ุณ ู„ู„ุฏูƒุชูˆุฑ ุงู†ู‡ ุจู„ุจุณ contactless
135
00:11:56,300 --> 00:12:02,040
ุชู„ุงู‚ูŠ ุญุงุณุณ ุงู†ู‡ ูƒุชูŠุฑ ููŠู„ู… ุจุตูŠุฑ disturbedูˆ ุฑู‚ูŠู‚ ูˆ
136
00:12:02,040 --> 00:12:05,140
ุฅุดูŠ ุงู„ุนุฏุณุฉ ุงู„ู„ูŠ ู‡ุชุณูƒุจ .. ู…ุด ู‡ูŠ ุงู„ุจูŠุฆุฉ ุจุชุงุนุชู‡ุงุŒ
137
00:12:05,140 --> 00:12:08,180
ุงู„ุนุฏุณุฉ ุงู„ู„ูŠ ู‡ุชุณูƒุจ ู‡ูŠ ุชุฑุชูŠุจ ูู„ู…ุง ูŠูƒูˆู† ููŠ ู‚ุทุน ุงู„
138
00:12:08,180 --> 00:12:12,560
comfort ูƒู„ ุดูˆูŠุฉุŒ ูƒู„ ุณุงุนุฉุŒ ูƒู„ ุณุงุนุชูŠู†ุŒ ุฎุณุฑ ุงู„ุทู„ุจุฉุŒ
139
00:12:12,560 --> 00:12:19,780
ุจูŠูƒูˆู† .. ุจูŠุฎูู ู three ูˆ ู‡ุฐุง ุจู‡ู…ูƒูˆุง hormonal
140
00:12:19,780 --> 00:12:25,080
changes in women ุงู„ุชุฏูˆูŠุฑ ุงู„ู‡ุฑู…ูˆู†ูŠ ููŠ ุงู„ู†ุณุงุก can
141
00:12:25,080 --> 00:12:29,000
also modify the quantity or quality of tears
142
00:12:31,140 --> 00:12:34,000
ุงุณุชุฑูˆุฌูŠู† ูˆุจุฑูˆุฌูŠุณุชุฑูˆู„ ุชุนุฑููŠู† ููŠู‡ ุงู†ุฏุฑุณุงู† ุงุณุชุฑูˆุฌูŠู†
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00:12:34,000 --> 00:12:38,580
ูˆุจุฑูˆุฌูŠุณุชุฑูˆู„ ูˆู‡ูˆ ูŠุนู†ูŠ ุงู„ู‡ุฑู…ูˆู†ูŠู† ุงู„ุงู†ุณูˆูŠูŠู† ุงู„ู„ูŠ ู‡ู…
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00:12:38,580 --> 00:12:44,120
ุจุชุนุงู‚ุจูˆุง ู„ุฐู„ูƒ ูŠุนู†ูŠ ุญุชู‰ ู„ูˆ ูˆู‚ุน ุจุฏู‡ ุทุงู„ุจุฉ ุงูˆ ุณุช ูŠุนู†ูŠ
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00:12:44,120 --> 00:12:48,960
ุชุนู…ู„ ู„ุงุฒูƒ ู…ุซู„ุง ููŠ ูุชุฑุฉ ุงู„ุฑุถุงุนุฉ ุงูˆ ุงู„ุญู…ุถ ู…ุงู†ุฎู„ุงุด
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00:12:48,960 --> 00:12:53,600
ุชุนู…ู„ ู…ู…ูƒู† ุงู†ู‡ุง ุฏุฑุงุฌ ู†ุนู… ู…ู…ูƒู† ุงู†ู‡ุง ุฏุฑุงุฌ ุงูˆ ุชุบูŠุธ
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ู†ูุณูƒ ุงูŠูˆุฉ ุงู‚ูˆู„ ุญุชู‰ ููŠ ุงู„ elasticity ุงูˆ ุฏู‚ูˆู†ุฉุณูˆุฑูŠ
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ููŠ ุงู„ electricity of the cornea ุจูŠูƒูˆู† ููŠู‡ ุชุบูŠูŠุฑ
149
00:13:03,640 --> 00:13:07,760
ู„ุฐู„ูƒ ุงุฐุง ุจุฏู†ุง ู†ุนู…ู„ ุงุญู†ุง ุงูŠ procedure ููŠ ุงู„ cornea
150
00:13:07,760 --> 00:13:12,340
ุจุฏู†ุง ู†ุนู…ู„ู‡ ููŠ ุงูˆู‚ุงุช ู…ุงููŠุด ููŠู‡ุง hormonal changes in
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females ูุงู„ุงู† ู†ุฑุฌุน ุชุงู†ูŠ ุจุงู„ู†ุณุจุฉ ู„ู„ lens wearing
152
00:13:20,860 --> 00:13:27,280
females ู‡ุชู„ุงู‚ูŠ ููŠ ุงุญูˆุงู„ ุชุบูŠุฑ ู‡ุฑู…ูˆู†ูŠ ุงู†ู‡ ู„ุง ุชุชู‚ู„ุน
153
00:13:27,280 --> 00:13:32,390
ุณู„ุณู„ุฉ ูƒุงููŠุฉู„ุฃู†ู‡ ุจูŠุนู…ู„ูˆู‡ุง ู…ู† ุงู„ dryness ุงูˆ ุงู„ุทุฑุงุจ
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ุญุชู‰ ููŠ ุงูุฑุงุฒ ุงู„ุงูƒูŠูˆุณุชูŠุฑุฒ ูˆ ุญุชู‰ ุงู„ู„ูŠ ู‡ูˆ ุงู„
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limousine ุทูŠุจ ูŠุจู‚ู‰ ุงู„ comfort ุงุญู†ุง ู…ู‚ูˆู„ู‡ุงุด ุงู†ุฒูŠู…ูŠุฉ
156
00:13:45,210 --> 00:13:50,570
ูˆ ุบูŠุฑ ุงู†ุฒูŠู…ูŠุฉ ูŠุนู†ูŠ ู‡ูŠ wetting ุงูŠู‡ ุฌุงู†ุจ ูƒู„ ุณุงุนุฉ
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00:13:50,570 --> 00:13:55,050
ุณุงุนุชูŠู† ุงู„ู„ูŠ ุนุงุฏู‰ ุณู„ุงุณู‚ุฉ ุจูŠุญุท ู†ู‚ุทุฉ ู‡ู†ุง ูˆ ู†ู‚ุทุฉ ู‡ู†ุง
158
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ุจุบุฑุถ ุงู†ู‡ ูŠุฌุนู„ ุนุฏุณุฉ ุงู„ู„ุงุณู‚ุฉ smoothูˆ conditioning ูˆ
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ูŠุชุฑุฏ ุฃูŠ ุฏุณุช ุชุงู†ูŠ ูŠุนู†ูŠ ุงุนู…ู„ ู…ุณุงุนุฏ ู…ุงุฌูˆู„ุงุด ุงู†ู‡ ุงุนู…ู„
160
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ู…ู†ุธู ุฒูŠ ุงู„ู‡ูŠุฏุฑูˆุฌูŠู† ุจุงู„ุฅูƒุณุงูŠุฏ ู…ุซู„ุง ู…ุงุฌูˆู„ุงุด ุทุจ
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alternative methods of hydrogel contact lens
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disinfection ุงู„ุญู‚ูŠู‚ุฉ ุงู†ุง ุจุชูƒู„ู… ุนู„ู‰ ุงุณุชุฎุฏุงู… ุงู„ุฅุดุนุงุน
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ุฎุงุตุฉ ุงู„ ultraviolet ูˆ ุงู„ ultrasound ููŠ ูŠุนู†ูŠ ุชุนู‚ูŠู…
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ุงู„ุนุฏุณุฉ ุงู„ู„ุงุตู‚ุฉุทุจ ู…ู† ุงู„ูˆุงุถุญ ุงู† ุงุณุชุฎุฏุงู… ุงู„ ultra
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violet ุงูˆ ุงู„ ultra sound ู‡ุฐุง ุจุชุงุน ุงู„ู„ูŠ ู‡ูˆ ุดุฑูƒุงุช ูˆ
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00:14:37,420 --> 00:14:43,480
ู…ุตุงู†ุน ู…ุด ูŠุนู†ูŠ user ุฒูŠู†ุง ู…ุด user ูˆุจุงู„ุชุงู„ูŠ ูŠุนู†ูŠ ุงุญู†ุง
167
00:14:43,480 --> 00:14:47,660
ุจู†ู‚ุฏุฑ ู†ู‚ูˆู„ ุงู† ู‡ุฐุง ู„ู„ุนู„ูŠุณุงุช ุงู„ู„ูŠ ุงุซู‚ู‰ ุงู„ fresh
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ุงู„ุญุฏูŠุซุฉ ุงูˆ ุงู„ุฌุฏูŠุฏุฉ ุงู„ุนู„ูŠุณุงุช ุงู„ู„ูŠ ุงุซู‚ู‰ ุงู„ุฌุฏูŠุฏุฉ ู…ุง
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ุจุญุทูˆู„ู‡ุง hydrogen peroxide ูˆู„ุง ุจุญุทูˆู„ู‡ุง enzymesู„ุฃ
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ุจุงู„ุฌู…ู„ุฉ ุงู„ู…ุตุงู†ุน ุจุงู„ู…ูŠุช ุฃู„ู ูˆ ุจุงู„ู…ูŠุชูŠู† ุฃู„ู ุนู†ุณุฉ
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ุจู†ุฎู„ู‡ู… ุนู„ู‰ ุงู„ ultra bio ุทุจุนุง ุงู„ ultra bio ุชุณุชุญูŠู„
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ุชุญุชู‡ุง ุฃูŠุด ุฃูŠุด ู…ุงูŠูƒุฑูˆุจ ุงูˆ ุจูƒุชูŠุฑูŠุง ุงูˆ ูุงู†ุฌุณ ุญุชู‰ ุงูˆ
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ููŠุฑูˆุณ ู„ุฐู„ูƒ ุงู„ุงู† ุงู„ู…ุตุงู†ุน ุฑูƒุฒูˆุง ุนู„ู‰ ุงูŠุด ุงู†ุง ุจู‚ูˆู„ูƒ
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ุงู†ุง ุจุนู…ู„ ุนู†ุณุงุช ุฌุฏูŠุฏุฉ ุฑุฎูŠุตุฉshort duration ุงูŠู‡ short
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duration ูุชุฑุฉ ู‚ุตูŠุฑุฉ ูŠุนู†ูŠ ูุชุฑุฉ ู‚ุตูŠุฑุฉ ู†ู„ุจุณู‡ุง ุงุณุจูˆุน
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ุงุณุจูˆุน ูŠุนู†ูŠ ูˆูุฏู‡ ู†ุจุณู‡ุง ู…ุงูŠุตูŠุฑ ุนู„ูŠู‡ุง protein ูˆ ู…ุง
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protein ูˆ ู†ุญุท ุนู„ูŠู‡ุง ุชุญุชูŠู† ูˆู„ุง ู„ุฃ ู„ุฃ ุงุฑู…ูŠู‡ุง ูˆ
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ู†ูŠุจุบูŠู‡ุง ู„ูŠุด ุชูƒูˆู† ู…ุซู„ุง ู…ุซู„ุง ุจู…ุงุฆุฉ ุฏูˆู„ุงุฑ ู„ุฃ ุชูƒูˆู†
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ุจุนุดุฑุฉ ุฏูˆู„ุงุฑ ููŠ ุงู„ุชููƒูŠุฑ ุงู„ุฅุชุตุงู„ูŠ ุจุชุงุนูƒ ุจู‚ูˆู„ูƒ ุฃู†ุง
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ุจู†ุชุฌ ุจุงู„ุนุดุฑุฉ ุฏูˆู„ุงุฑ ูˆ ุจุจูŠุน ุฃูƒุชุฑ ูุฏู‡ ุนู†ุฏู…ุง ุฃุญุท ุนู†ุฏู‡
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ู…ูŠุฉ ุฏูˆู„ุงุฑ ุชุจุชุนุฏ ุณู†ุชูŠู† ุชู„ุงุชุฉ
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ุจุนุถู‡ู… ูƒุงู†ูˆุง ูŠูƒูˆู†ูˆุง ูู‚ุท ู…ูุงุฌุฆูŠู† ุจุดูƒู„ ู…ุจุงุดุฑ ุนู†ุฏู…ุง
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ูŠูƒูˆู†ูˆุง ู…ุญุงูˆู„ูŠู† ู…ุญุงูˆู„ุฉ ู…ูŠูƒุฑูˆ ุจูŠูˆุฌูŠูƒุงู„ ุนู†ุฏู…ุง ูŠูƒูˆู†
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ู‡ู†ุงูƒ ุจูƒุชูŠุฑูŠุง ู†ู‚ู„ ุงู„ุจูƒุชูŠุฑูŠุง ู†ุฑู‰ ุงู„ู…ูุงุนู„ ูู…ุซู„ุง ููŠ
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ุณู†ุฉ ุชุณุนุฉ ูˆ ุชู…ุงู†ูŠู† ุตุงุฑ ุจุญุซ ูˆ ูˆุฏุฏูˆุง ุงู†ู‡ ู…ูŠุชูŠู† ูˆ
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ุชู„ุงุชุฉ ูˆุณุจุนูŠู† ูˆุณุจุน ู…ู† ุนุดุฑุฉ ู†ุงู†ูˆ ู…ุชุฑ ultravioletwith
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an intensity of one thousand one hundred one per
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cubic centimeter achieved satisfactory
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disinfection with short exposure times ูŠุนู†ูŠ ุฏู‚ุงูŠู‚
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ู…ุนุฏูˆุฏุฉ ุชู‚ุฑูŠุจุง ูƒู„ ุงู„ู…ูŠูƒุฑูˆุจุงุช ู…ุงุชุช ููŠ ู‡ุฐุง ุงู„ุทูˆู„
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ุงู„ู…ูˆุฌูŠ ู‚ุงุฏุฉ ุงู„ ultra viral ูู…ุซู„ุง ุดุงููˆุง ุงู„ู„ูŠ ุฃูƒู„ ููŠ
192
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ู…ูˆุจุง ุงู„ู„ูŠ ู‡ูˆ ู‚ุฏุงู… ุงู„ุนุฏูˆู‰ ุงู„ู‚ุฑู†ูŠุฉ ู‚ุนุฏุช ุจูˆุฑูุงุฌุฉ
193
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ููŠ ุฃู‚ู„ ู…ู† ุซู„ุงุซ ุฏู‚ุงุฆู‚ ููŠ ุงู„ุชู„ุงุชุฉ ูˆุชุณุนูŠู† ู‡ุงุฑูŠุณ ุนุงู…ู„
194
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ุจุญุซ ุจุฑุถู‡ ุจู‚ู‰ concluded that ultraviolet radiation
195
00:16:56,600 --> 00:16:59,800
of this wavelength is an effective and rapid
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method of disinfecting contact lenses ุจุณ ู‚ู„ุช ู‡ูŠ ุฏู‡
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ู…ุด ููŠ ุงู„ุจูŠุช ุนู†ุฏู‡ุงุŒ ู‡ูŠ ุฏู‡ ุดุบู„ ุฅูŠุดุŸ ุดุฑูƒุงุช ูˆู…ุตุงู†ุนุŸ
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ุทุจุนุง ู‡ุฐูŠู† care ุฃูˆ heavily care of ุทูŠุงู„ุฉูุจู‚ู‰ try on
199
00:17:16,310 --> 00:17:23,390
lenses ุงู„ู„ูŠ ู‡ูŠ ุงุณุชุฎุฏู…ู‡ุง ุงุญู†ุง ู„ุฅูŠุด ู„ู„ุชุฌุฑูŠุจ ู†ุจุชุฏุฃ
200
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ุฎุงุตุฉ ููŠ ุงู„ heart ููŠ ุงู„ heart ุงูˆ ุงู„ rigid ูŠุนู†ูŠ ุจุฏู†ุง
201
00:17:28,830 --> 00:17:32,450
ู†ุดูˆู ุฑุงุญุฉ ุงู„ู…ุฑูŠุถ ู…ู† ู†ุงุญูŠุฉ ุงู„ fitness ูˆ ู…ู† ู†ุงุญูŠุฉ ุงู„
202
00:17:32,450 --> 00:17:36,310
.. ุงู„ู„ูŠ ู‡ูˆ ุงู„ optical power ูˆ ู…ู† ู†ุงุญูŠุฉ ุงู„ shape ูˆ
203
00:17:36,310 --> 00:17:39,830
ู…ู† ู†ุงุญูŠุฉ ุงู„ุฑุงุญุฉ ุนุฏุฉ ุญุงุฌุงุช ูุงุญู†ุง ุจุฏู†ุง ู†ุดูˆู
204
00:17:49,570 --> 00:17:53,010
ููŠ ุงู„ูˆู„ุงูŠุงุช ุงู„ู…ุชุญุฏุฉุŒ 96% ู…ู† ุงู„ู…ุณุชุฎุฏู…ูŠู† ู„ู„ู…ุตุจุงุญ
205
00:17:53,010 --> 00:17:53,930
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
206
00:17:53,930 --> 00:17:56,770
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
207
00:17:56,770 --> 00:18:07,330
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
208
00:18:07,330 --> 00:18:09,310
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
209
00:18:09,310 --> 00:18:09,410
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
210
00:18:09,410 --> 00:18:09,830
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
211
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ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
212
00:18:10,970 --> 00:18:12,270
ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ
213
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ุงู„ุฌุฏูŠุฏ ู„ู„ู…ุตุจุงุญ ุงู„ุฌ
214
00:18:44,370 --> 00:18:50,430
ููŠ ุญุงู„ุงุช ุงู„ rigid lenses ุบุงู„ูŠุฉ rigid lenses
215
00:18:55,470 --> 00:18:58,650
It is usually considered to be necessary to
216
00:18:58,650 --> 00:19:02,510
evaluate the fit of several lenses from a non
217
00:19:02,510 --> 00:19:05,930
-disposable fitting set to decide the
218
00:19:05,930 --> 00:19:10,370
specification to be ordered ูŠุนู†ูŠ ุฃู†ุง ุตุญูŠุญ ุจุญุท
219
00:19:10,370 --> 00:19:13,970
ุงู„ุฃูˆู„ู‰ ุนู„ุณุฉ ุจุดูˆูุด ููŠู‡ุง ูƒูˆูŠุณ ุงู„ุชุงู†ูŠุฉ ุฃุญุณู† ุงู„ุชุงู„ุชุฉ
220
00:19:13,970 --> 00:19:17,910
ุฃุญุณู† ุจุณ ู‡ู†ุฌุฑุจ ุชู„ุงุชุฉ ุนุฏุณุงุช ู‡ุฐู‡ ุงู„ุชู„ุงุชุฉ ุนุฏุณุงุช ุตุงุฑูˆุง
221
00:19:17,910 --> 00:19:23,090
contaminated ู…ู†ู‡ู… ูƒุฏู‡ู‡ู„ ู‡ูˆ ู„ุนูŠุจุชู‡ู… ูƒุฏู‡ ู„ู€
222
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disposableุŸ
223
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ู„ุฃุŒ ู„ุฅู†ูŠ ุญุงูุธ ุนู„ูŠู‡ู…ุŒ ูุงู†ูŠ ุฃุนู…ู„ู‡ู… ูƒุฏู‡ ุงู„ู€ use of
224
00:19:29,950 --> 00:19:33,490
trial lenses assumes particular importance when
225
00:19:33,490 --> 00:19:36,590
complex designs such as bifocals are to be
226
00:19:36,590 --> 00:19:41,250
supplied ูˆ ุฃูƒุชุฑ ุฃู‡ู…ูŠุฉ ู„ู…ุง ุชูƒูˆู† ุงู„ contact ู‡ุงู„ูŠ
227
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bifocal ุฃูˆ trifocal
228
00:19:48,640 --> 00:19:53,080
multifunction ู…ุด ู…ุนู‚ูˆู„ ุงู†ู‡ุง ู…ูƒู„ูุฉ ุงู†ูŠ ุฃู„ู‚ูŠู‡ุง ูุจุฏู‡ุง
229
00:19:53,080 --> 00:20:00,540
ูƒูŠู„ ุจุฏู‡ุง ุชููŠู„ ูˆุจุฏู‡ุง ู†ุญุทู‡ุง ููŠ hydrogen peroxide ู‡ูŠูƒ
230
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ู‡ู… ุจูŠูƒู…ู„ู†ุง ู…ูˆุถูˆุน solutions of contact lenses ูˆุงู„ุขู†
231
00:20:03,360 --> 00:20:07,300
ู‡ู†ุจุฏุฃ ููŠ therapeutic drugs and their uses ุงู„ุฃุฏูˆุฉ
232
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ุงู„ู„ูŠ ุชุณุชุฎุฏู… ููŠ ุนู„ุงุฌ ุงู„ุนูŠู† ููŠ ุนู„ุงุฌ ุงู„ุนูŠู† ุจู‚ูˆู„ู„ูŠ
233
00:20:12,760 --> 00:20:17,540
ุจุงุฎุชุตุงุฑ ูƒู„ู…ุฉ Anti-infective ูŠุนู†ูŠ ู…ุถุงุฏ
234
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effective against a variety of infections ูŠุนู†ูŠ ุทูŠุจ
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ูˆุงุณุน ู…ู† ุงู„ูƒุงุฆู†ุงุช ุงู„ู„ูŠ ุจุชุนู…ู„ infection ู…ุซู„ุง
236
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viruses, rickettsia, bacteria, fungi and so on
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rickettsia ู‡ูŠ ูƒุงุฆู†ุงุช ู…ุง ุจูŠู† ุงู„ูุฑูˆุณุงุช ูˆ ู…ุง ุจูŠู†
238
00:20:40,930 --> 00:20:45,710
ุงู„ุจูƒุชูŠุฑูŠุง ุฒูŠ ุงู„ู„ูŠ ุจุชุนู…ู„ ุงู„ syphilis rickettsia
239
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ูŠุจู‚ู‰ ู‡ูˆ ุจูŠู‚ูˆู„ ูŠุนู†ูŠ ุงู†ุง ุงุทู„ุจ ู…ู†ูŠ ุงู†ูŠ
240
00:20:59,600 --> 00:21:05,440
ูˆ ู„ุง ุงู„ุจุฑูˆุชูˆุฒูŠูˆู‡ ุฃูƒุงุฑุซูˆู…ูˆุจู‡ ูˆู„ุง ุงู„ูุงู†ุฌุงูŠ ูˆ ุญุชู‰ ู„ุง
241
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ุงู„ุฑูƒุณูŠุง ู„ูˆ ุฎุดุช ุงู„ุขู† ู„ูˆ ุฃู†ุง ู…ุงุนู†ุฏูŠุด ู‡ุฐู‡ ุงู„ู…ู†ุธูˆู…ุฉ ู…ู†
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ุงู„ู…ุถุงุฏุงุช
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ุจุชุงุนุฉ ุงู„ infection ุนูŠูˆู† ุงู„ุจุดุฑ ุงูŠุด ุจูŠุตูŠุฑ ููŠู‡ุงุŸ
244
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ู…ุตูŠุจุฉ ู…ุตูŠุจุฉ ุงู„ู…ูŠูƒุงู†ูŠุฒู… of action of these agents
245
00:21:24,460 --> 00:21:29,490
varies greatlyูƒูŠู ุชุนู…ู„ุŸ ุงุญู†ุง ุจุชุญุฏุซู†ุง ุฃูˆ ุจุชุญุฏุซ ูƒูŠู
246
00:21:29,490 --> 00:21:34,810
ุชุนู…ู„ ุงู„ู…ุถุงุฏุงุช ุงู„ุญูŠูˆูŠุฉ ุงู„ุจูƒุชูŠุฑูŠุง ู…ุซู„ุง ูู…ู†ู‡ุง ู…ู† ูŠู…ุฒู‚
247
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ุงู„ cell wall ูˆู…ู†ู‡ุง ู…ู† ูŠุชุญุฏ ุจู€ ribosomes ุจู†ุงุกู‡ุง ู…ู†
248
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ุชูƒูˆูŠู† .. ู„ูŠุดุŸ
249
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ุทุงู‚ุฉ .. ribosomes ู„ูŠุดุŸ ุจุชุฎู„ูŠู‡ุง low levels of
250
00:21:49,330 --> 00:21:53,750
energy ุงู‡ ุทูŠุจ ูˆู…ู†ู‡ุง ู…ู† ูŠู‡ุงุฌู… in Euclides
251
00:22:03,610 --> 00:22:08,050
ูˆู‡ูƒุฐุง ุทูŠุจ ุทูŠุจ the mechanism of action of these
252
00:22:08,050 --> 00:22:11,690
agents varies greatly and to some extent will
253
00:22:11,690 --> 00:22:14,310
depend on the organism on which the particular
254
00:22:14,310 --> 00:22:18,390
agent acts ูƒู…ุงู† ุจุนุชู…ุฏ ุนู„ู‰ non-microbe ู‡ู„ูŠ ุงุณุชุฌูŠุจ
255
00:22:18,390 --> 00:22:22,180
ูˆู„ุง ู„ุงูŠุณุชุฌูŠุจIn the majority of cases however some
256
00:22:22,180 --> 00:22:27,300
competitive inhibition of a biochemical process is
257
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involved as a result of the concentration level
258
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ูŠุจู‚ู‰ ุฃุญูŠุงู†ุง ููŠ ุฏูˆุงุก ูŠุณุชุฎุฏู… ุจ level ู‚ู„ูŠู„ ู„ูƒู† ุจูŠูƒูˆู†
259
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effective ูˆููŠ ุงู„ุนูƒุณ ุฏูˆุงุก ูŠุณุชุฎุฏู… ุจ concentration
260
00:22:41,800 --> 00:22:46,060
ุนุงู„ูŠ ูˆ ุจูŠูƒูˆู† ุชุฃุซูŠุฑู‡ ุถุนูŠู ุญุณุจ ุงู„ู…ุนูŠูƒ ูˆุงู„ ู…ูŠุจูƒ ุงู„ู„ูŠ
261
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ุฃุฎุฏู†ุงู‡ ู‚ุจู„ู‡ุง
262
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Drugs for the treatment of infections ู‚ูˆู„ู†ุง ููŠ ุดูŠุก
263
00:23:05,950 --> 00:23:10,550
ุงุณู…ู‡ MIC Minimum
264
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Inhibitory Concentration are often published for
265
00:23:15,630 --> 00:23:19,710
the common anti-infective drugsุจู‚ูˆู„ ู„ูŠ these
266
00:23:19,710 --> 00:23:26,590
values ูŠุนู†ูŠ ูƒู„ drug ุฅู„ู‡ MikeุŒ these values will
267
00:23:26,590 --> 00:23:31,510
vary according to the infecting organism ูŠุนู†ูŠ
268
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Staphylococcus aureus ู…ุซู„ุง ุชุฎุชู„ู ุนู† Staphylococcus
269
00:23:35,330 --> 00:23:41,210
epidermidis ูŠุนู†ูŠ ู‡ุฐุง ู…ูŠูƒุฑูˆุจ ู…ุชุนุงูŠุด Flora ูˆ ู‡ุฐุง
270
00:23:41,210 --> 00:23:48,570
ู…ูŠูƒุฑูˆุจ ุดุฑุณูุงู†ุง ุจุฏูŠ ู…ูŠูƒ ูŠูˆุทูŠ ุงู„ุจูƒุชูŠุฑูŠุง ุงู„ุดุฑุณุฉ ุญุชู‰
271
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ูŠุนู†ูŠ ู„ุง ุชูุนู„ ู…ุถุงุนูุฉ ุงู‡ ุจูŠู‚ูˆู„ูŠ the might for a
272
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strain of Methicillin-resistant Staphylococcus
273
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aureus is considerably higher than that of normal
274
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Staphylococcus aureus ูŠุนู†ูŠ ุจูŠู‚ูˆู„ูŠ ุญุชู‰
275
00:24:04,730 --> 00:24:07,950
Staphylococcus aureus ููŠ ู…ู†ู‡ุง ูŠุญุทู… ุฃู†ูˆุงุน ุงู„ุจู†ุณุงู„ูŠ
276
00:24:07,950 --> 00:24:09,890
ูˆูŠุญู„ู„ู‡
277
00:24:11,380 --> 00:24:14,680
ูุงุจุฏู‰ ุงู†ุง ุนู„ุงุฌ ูŠูƒูˆู† ุงู„ mic ุจุชุงุนู‡ ูŠุชู†ุงุณู‰ ููŠ ู‡ุฐู‡
278
00:24:14,680 --> 00:24:21,680
ุงู„ุดุฑุงุณุฉ ูˆู‡ุฐู‡ ุงู„ู…ู‚ุงูˆู…ุฉ ุจุงุฎุชู„ุงู ุงู„ู„ู‰ ู‡ูˆ ุงู„ุงุณุชูุญุงุฉ
279
00:24:21,680 --> 00:24:27,160
ุงู„ูƒุงุณูŠุฉ ุงู„ุนุงุฏูŠุฉ ุงู„ู„ู‰ ู…ุง ุจุชุนู…ู„ ุชูƒุณูŠุฑ ู„ุฅูŠุด ู„ุงุชูุงุชูƒุณ
280
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when it comes to treating ophthalmic infections
281
00:24:38,520 --> 00:24:42,060
There are many more factors to take into
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00:24:42,060 --> 00:24:46,020
consideration ูŠุจู‚ู‰ ุฃู†ุง ููŠ ุงู„ุฃูˆู„ ุจุฃุชูƒู„ู… ุนู† ุงู„ุชู‡ูŠุจุงุช
283
00:24:46,020 --> 00:24:51,080
ุงู„ุฑุฆุชูŠู†ุŒ ุงู„ุชู‡ูŠุจุงุช ุงู„ุญู„ู‚ุŒ ุงู„ุชู‡ูŠุจุงุช ุงู„ุฃู…ุนุงุกุŒ
284
00:24:51,080 --> 00:24:55,100
ุงู„ุชู‡ูŠุจุงุช ุงู„ู…ุฌุงู„ ุงู„ู…ูˆู„ูŠุฉุŒ ู„ูƒู† ูŠู‚ูˆู„ู†ุง ุงุญู†ุง ุงู„ุนูŠู†
285
00:24:55,100 --> 00:25:02,260
ุชุฎุชู„ูุŒ ุงู„ุนูŠู† ุฅู‚ู„ูŠู… ุดุจู‡ ู…ุณุชู‚ู„ุŒ ุงุฐุง ุฃู‚ูˆู„ ูƒูˆู† ูุฏุฑุงู„ูŠุŒ
286
00:25:02,260 --> 00:25:05,920
ูƒูˆู† ูุฏุฑุงู„ูŠุŒ ู…ุด ูุฏุฑุงู„ูŠ ุจู‚ู‰ ูŠุนู†ูŠุŒ ุงู„ุนูŠู† ุฏุฎูˆู„ู‡ุง
287
00:25:05,920 --> 00:25:11,160
ูˆุฎุฑูˆุฌู‡ุง ู…ุด ุณู‡ู„ุŒ ููŠู‡ ุจุฑูŠุฆุฉูู„ู…ุง ุงุชูƒู„ู… ุงู†ุง ุงู„ุขู† ุจุฏูŠ
288
00:25:11,160 --> 00:25:17,700
ุงู†ุง ุงูˆุฌุฏ ุงุดูŠุงุก ุชุคุซุฑ ููŠ ุงู„ุนู„ู… ุงูˆ ุงู„ุนู„ุงุฌ ูŠุคุซุฑ ููŠู‡ุง
289
00:25:17,700 --> 00:25:22,900
ููŠ ุงู„ุนู„ู… ุงุฎุชู„ู ุนู† ุจุงู‚ ุงู„ุฌุณู… ูู…ุซู„ุง when the locus
290
00:25:22,900 --> 00:25:26,620
or site of infection will determine not only the
291
00:25:26,620 --> 00:25:30,120
route of the administration but also the prognosis
292
00:25:30,120 --> 00:25:35,240
infections of the anterior eyeูŠุนู†ูŠ ููŠ ุงู„ eye
293
00:25:35,240 --> 00:25:39,620
segment ู‚ุตุฏู‡ู… ูŠุนู†ูŠ ุญุงุฌุงุช ููŠ ุงู„ู‚ุฑู†ูŠุฉ ูˆ ููŠ ุงู„ AC ูˆ
294
00:25:39,620 --> 00:25:43,400
ุญุชู‰ ููŠ ุงู„ iris ุชุฎุชู„ู ุนู† ุฃุดูŠุงุก ููŠ ุงู„ retina back
295
00:25:43,400 --> 00:25:47,580
further back ูŠุนู†ูŠ ุตุญูŠุญ ุฃู†ุง ู…ู‡ู„ ุจุฏูŠ ุนุงู„ุฌ ุดูŠุก ููŠ
296
00:25:47,580 --> 00:25:51,660
ุงู„ู‚ุฑู† ุงู‡ ุฒูŠ ุจุฏูŠ ุนุงู„ุฌ ุดูŠุก ููŠ ุงู„ retina ุงูˆ ุงู„ูุชุฑูŠุงุณ
297
00:25:51,660 --> 00:25:55,060
ุทุจุนุง ู…ุฎุชู„ู ุงู„ retina ูˆ ุงู„ูุชุฑูŠุงุณ ุจูŠุจู‚ูˆุง injection
298
00:25:55,060 --> 00:26:00,700
ุฑุชุฑูˆ ุจุฑุจุฑ ุงู‡ ุฑุชุฑูˆ ุจุฑุจุฑ ุจูŠุฌูŠุจูˆู‡ ู…ุด ุงู„ู‚ุทุฑ ุงูˆ ุงู„ู‚ุฑู†
299
00:26:00,700 --> 00:26:04,860
ู…ู† ู‡ุฐุงูู‡ูŠ ู…ุซู„ุง consideration ู…ุด ู…ูˆู„ูˆุฏ ููŠ ุฌุณู…ู‡ุงุŒ
300
00:26:04,860 --> 00:26:07,240
ุฃู‡ู… ุงู„ุงุณู… ู…ู†ู‡ุง ุฃุฎุฏู‡ุง ุงู„ุฃู‚ุฑุงุณ ุฃูˆ ุงู„ุญุฌูˆู†ุฉ ูˆุงู„ุฏู…
301
00:26:07,240 --> 00:26:11,480
ุจูŠุดูŠู„ุŒ ุจูŠูˆุฒุนุŒ ุจูŠูˆุฒุนุŒ ู„ูƒู† ุงู„ุฏู… ู…ุงุจุชุฏุงุด ูŠูˆุฒุน ุนู„ู‰
302
00:26:11,480 --> 00:26:15,740
ุงู„ุนูŠู†ุŒ ุงู„ุฏู… ูŠูˆุฒุน ู…ุซู„ุง ุนู„ู‰ ุงู„ู„ูŠ ู‡ูˆ ุงู„ุฑุฆุชูŠู† ูˆุนู„ู‰
303
00:26:15,740 --> 00:26:18,220
ุงู„ู„ูŠ ู‡ูˆ ุงู„ู‚ู„ุจ ูˆุนู„ู‰ ุงู„ุญุงุฌุงุช ู‡ุฐู‡
304
00:26:25,940 --> 00:26:33,240
ูˆุงู„ู„ู‡ ูˆุงุญุฏ ู…ุน severe acute endocyclitis ู…ู…ูƒู† ุงุนุทูŠู‡
305
00:26:33,240 --> 00:26:38,100
cortison ูƒู„ ุณุงุนุฉ ุงูˆ ูˆุงุญุฏ ุทุงู„ุน ู…ู† intraocular
306
00:26:38,100 --> 00:26:43,080
operation ุทุงู„ุน ู…ู† ultra intraocular operation ูƒู„
307
00:26:43,080 --> 00:26:48,160
ุณุงุนุฉ ูˆ ุณุงุนุชูŠู† ุจุฏูŠ ุงุนุทูŠู‡ ู‚ุทุฑุงุช ุฌูˆูŠุฉ ู„ูƒู† ูˆุงุญุฏ ู…ุน
308
00:26:48,160 --> 00:26:55,250
ุดูˆูŠุฉ infection ููŠ ุงู„ู…ู„ุชุญู…ุฉ ุฌุฏ ุฌุงุช ูŠุนู†ูŠูƒู„ ุณุช ุณุงุนุงุช
309
00:26:55,250 --> 00:26:59,870
ู‚ุทุฑุฉ ุฃูู„ูˆุณ ูƒู„ ุณุช ุณุงุนุงุช ูุงู„ุงู‡ุชู…ุงู… ุญุณุจ ุงู„ label of
310
00:26:59,870 --> 00:27:05,350
inflammation ู‡ู„ ุงู„ inflammation ุดุฏูŠุฏ ูˆู„ุง ู…ุด ุดุฏูŠุฏ
311
00:27:05,350 --> 00:27:09,390
ุงู„ุงู‡ุงู… ุงู„ุชุงู„ุช ููŠ ุงู„ุนูŠู† ุชูŠุฑูŠ ูู„ูˆ ูˆ ุงู„ similarly
312
00:27:09,390 --> 00:27:13,350
affect the absorption of anti-infective agents
313
00:27:13,350 --> 00:27:16,770
ูŠุนู†ูŠ ุงู„ุดุจุงุจ ุนู†ุฏู‡ู… ุชูŠุฑูŠ ูู„ูˆ normal ูˆ ู‚ูˆูŠ
314
00:27:26,170 --> 00:27:32,150
ู‡ู†ุง ุงู„ .. ูŠุนู†ูŠ ููŠ ุชูุงุนู„ ูˆ ููŠ ุฏูˆุงุจุงู† ู„ู„ .. ุงู„ .. ุงู„
315
00:27:32,150 --> 00:27:36,010
.. ุฅูŠุดุŸ ุงู„ุฃุฌูˆูŠุฉ ูˆ ููŠ ุงุณุชู‚ุจุงู„ ุฅู„ู‡ุง ูˆ absorption ู„ูƒู†
316
00:27:36,010 --> 00:27:39,950
ูˆุงุญุฏ ู…ุน dry eye ูŠุนู†ูŠ ูˆ ุฏู‡ ุตุญ ูˆุงุญุฏ ู…ุน dry eye ูˆุงุญุฏ
317
00:27:39,950 --> 00:27:49,290
ูˆ ุฏู‡ ุตุญ ุทูŠุจ ู‡ุชูƒู„ู… ุน ุงู„ bacteria ู„ุฃู†ู‡ ุงู„ .. ูŠุนู†ูŠ
318
00:27:49,290 --> 00:27:53,450
more than ninety percent of eye infections is ุฅูŠุดุŸ
319
00:27:56,230 --> 00:27:59,770
ูุจุชูƒู„ู… ุฏุงูŠู…ุง ุนู† ุงู„ุจูƒุชูŠุฑูŠุง ู„ูƒู† ู…ุด ู…ุน ุฐู„ูƒ ุงู„ููŠุฑูˆุณุงุช
320
00:27:59,770 --> 00:28:02,130
ุฅูŠู‡ ุงู„ู„ูŠ ูŠุนู†ูŠ ุฃู†ู†ุง ุฎุงุตุฉ ุงู„ herpes simplex
321
00:28:02,130 --> 00:28:06,370
ูƒูŠู„ูˆุชุงูŠุชุณ ุจุฑุถู‡ ุจู†ุฎุชุงุฑ ููŠู‡ู… ูุงู„ุจูƒุชูŠุฑูŠุง ุจู‚ูˆู„ as with
322
00:28:06,370 --> 00:28:10,930
most of pharma drugs the antibacterials used on
323
00:28:10,930 --> 00:28:14,410
the eye were originally blocked for systemic use
324
00:28:14,410 --> 00:28:21,990
ูŠุนู†ูŠ ุงุญู†ุง ู…ุณุชูˆุฑุฏู†ุงุด ู„ู„ุนูŠู† ู…ู† ุงู„ู‚ู…ุฑ ู…ุถุงุฏุฉ ุญูŠูˆูŠุฉ ู„ุฃ
325
00:28:21,990 --> 00:28:26,280
ุจู‚ูˆู„ ุงู„ู…ุถุงุฏุฉ ุงู„ุญูŠูˆูŠุฉ ุงู„ู„ูŠ ุจู†ุนุทูŠู‡ุง systemicูŠุนู†ูŠ
326
00:28:26,280 --> 00:28:33,320
ุงู„ุนู„ุงุฌ ุงู„ุฌู‡ุงุฒ ุงู„ุชู†ูุณูŠ ุงูˆ ุงู„ุฌู‡ุงุฒ ุงู„ู‡ุถู…ูŠ ุงูˆ ุงู„ุฌู‡ุงุฒ
327
00:28:33,320 --> 00:28:39,000
ุงู„ุจูˆู„ูŠ ุงู„ุชู†ุงุณู„ูŠ ู‡ูŠ ู†ูุณ ุงู„ู…ู†ุทู‚ุฉ ุงู„ุญูŠูˆูŠุฉ ุงู„ู„ูŠ
328
00:28:39,000 --> 00:28:47,040
ุจู†ุนุทูŠู‡ุง ู„ู„ุนูŠู† ุจุณ ุจุตูˆุฑุฉ drops to the point ู†ุดุชุงู‚
329
00:28:47,040 --> 00:28:54,310
ู…ู†ู‡ุง ูŠุนู†ูŠ ุงุดุชู‚ุงู‚ however in the mainIt is the ones
330
00:28:54,310 --> 00:28:58,830
that have no or very restricted systemic use that
331
00:28:58,830 --> 00:29:01,770
are most popular for treatment of the eye ุจุณ ููŠ
332
00:29:01,770 --> 00:29:08,310
ุญุงุฌุฉ ูŠุนู†ูŠ ู‡ูŠ ุญูƒู…ุฉ ูŠุนู†ูŠ ุฎู„ูˆู†ุง .. ุญูƒู…ุฉ ุจู‚ูˆู„ ูŠุนู†ูŠ ุงู†
333
00:29:08,310 --> 00:29:15,470
ููŠ ุจุนุถ ุงู„ุฃุฏูˆูŠุฉ ู‚ู„ูŠู„ุง ุชุณุชุฎุฏู… systemic ุฒูŠ ู…ุซู„ุง
334
00:29:15,470 --> 00:29:20,490
chlorine phenicol ู‚ู„ูŠู„ุง ุชุณุชุฎุฏู… systemic ู„ุฃู†ู‡ ุจูŠุนู…ู„
335
00:29:20,490 --> 00:29:22,270
ู…ุดุงูƒู„ ุนู„ู‰ ุงู„ุฏู…
336
00:29:26,090 --> 00:29:33,890
ุงู„ู…ู†ุงุน ูุจูŠุฎุงููˆุง ู…ู†ู‡ ุงู† ูŠูุนุทูˆู‡ ุฅู„ุง ูƒู‡ู„ุงุช ู†ุงุฏุฑุฉ ุจู‚ูˆู„
337
00:29:33,890 --> 00:29:40,490
ู‡ุฐุง ู„ู„ุนูŠู† ุฌูˆู‡ุฑูŠ ูˆุฏู‡ุจูŠ ู„ูŠุดุŸ ู„ุฃู† ุงู„ุฃุฏูˆูŠุฉ ุงู„ุนุงุฏูŠุฉ
338
00:29:40,490 --> 00:29:43,230
ุงู„ู…ุถุงุฏุฉ ุงู„ุญูŠูˆูŠุฉ ุงู„ุนุงุฏูŠุฉ ุงู„ู„ูŠ ุจู†ู…ุงู†ุนู‡ุง ูƒู„ ูŠูˆู…
339
00:29:43,230 --> 00:29:50,610
ุงู„ุจูƒุชูŠุฑูŠุง ุฅูŠุด ุจุชุนู…ู„ู‡ุงุŸ resistance ูŠุนู†ูŠ ุณุฑู‡ุง
340
00:30:00,880 --> 00:30:05,700
ุงุณุชุฎุฏุงู… ุงู„ antibiotic ุจูƒุชุฑุฉ ูƒู„ ู…ุง ุงู„ resistance
341
00:30:05,700 --> 00:30:12,800
ุฒุงุฏุช ู„ุฃู† ุงู„ุดูุฑุฉ ุฃูˆ ุงู„ุชุฑูƒูŠุจ ุงู„ูƒูŠู…ูŠุงุฆูŠ ูŠุนู†ูŠ ุงู‚ุตุฏ
342
00:30:12,800 --> 00:30:17,840
ุงู„ู…ุถุงุฑุถ ุงู„ุญูŠูˆูŠ ูŠุชูƒุดู ุงู„ููƒุณูŠุฑูŠ ุทูˆู„ ู†ูุณูŠ ุงูŠูˆุฉ ู„ูƒู†
343
00:30:17,840 --> 00:30:21,420
antibiotic ูˆู„ุง ููŠ ุงู„ุณู†ุฉ ุจูŠุณุชุฎุฏู… ู…ุฑุฉ ุงูˆ ู…ุฑุชูŠู† ุงูˆ
344
00:30:21,420 --> 00:30:28,380
ุชู„ุงุชุฉ ููŠ ู…ุฌุชู…ุน ู…ุง ู‡ุฐุง ู„ุนูŠู† ุฐู‡ุจูŠู„ุฃู† ู‡ูˆ ู…ุด ู‡ูŠุฑูˆุญ ุนู„ู‰
345
00:30:28,380 --> 00:30:32,080
ุงู„ุฏู… ูˆ ูŠุนู…ู„ ุงู„ู…ุดุงูƒู„ ุจุชุงุนุฉ ุงู„ .. ุงู„ู†ู‚ุทุฉ ุงู„ูˆุงุญุฏุฉ
346
00:30:32,080 --> 00:30:37,440
ุจุชุนู…ู„ุด .. ุจุชุนู…ู„ุด ูŠุฎู„ู‚ ุฅุถุงุกุฉ ูˆ ุงู„ู…ู†ุงุนุฉุŒ ุดุงูŠููŠู† ูƒูŠูุŸ
347
00:30:37,440 --> 00:30:40,560
ุฒูŠ ู…ุง ุฌุงู„ ุงู„ุดุนุฑุด ุฌุงู„ .. ุจุฐู„ูƒ ู‚ุฏุฑุช ุงู„ุฃูŠุงู… ูˆ ู…ุง ุจูŠู†ุง
348
00:30:40,560 --> 00:30:46,940
ุฃู‡ู„ูŠู‡ุง ู…ุตุงูŠุจ ู‚ูˆู… ุนู†ุฏ ู‚ูˆู… ููˆุงุฆุฏู‡ุŒ ุงู†ุช ู…ุด ุญุงูุธูŠู†ุŒ
349
00:30:46,940 --> 00:30:52,780
ุงู†ุช ูุงู‡ู… ุงู„ุดุนุฑุด ุตุญุŸ ุงู‡ุŒ ู…ุง ุจูŠู†ุง ุฃู‡ู„ูŠู‡ุง ููˆุงุฆุฏู‡ ู‚ูˆู…ุŒ
350
00:30:52,780 --> 00:30:57,440
ู…ุตุงูŠุจ ู‚ูˆู… ุนู†ุฏ ู‚ูˆู… ููˆุงุฆุฏู‡ุฒูŠ ูˆุงุญุฏ ุจูŠู‚ูˆู„ูƒ ูŠุนู†ูŠ ูŠุฑุงูƒุจ
351
00:30:57,440 --> 00:31:00,920
ุนู„ู‰ ุฌู…ู„ ูˆุฌู…ู„ ุงู„ู„ูŠ ู‡ูˆ ู‚ุงู„ ุจูŠู…ูˆุชุŒ ุดุงูŠู ู†ูุณูŠ ู‚ุงู„
352
00:31:00,920 --> 00:31:05,220
ู„ุญู‚ูˆู†ูŠ ุจุณูƒูŠู†ุฉุŒ ู„ุญู‚ูˆู‡ ุจุงู„ุณูƒูŠู†ุฉุŒ ุฐุจุญูˆู‡ ูˆ ู‚ุงู„ูˆุง ูˆ
353
00:31:05,220 --> 00:31:09,160
ุงู„ู„ู‡ ุบูŠุฑ ุงู†ูุฑู‚ูˆุง ุนู„ูŠู‡ุŒ ูู‡ู… ู‚ุงุนุฏูŠู† ูˆ ู‡ู… ู…ุด ุนุงุฑููŠู†
354
00:31:09,160 --> 00:31:13,200
ุงู†ู‡ ูŠุญุฌูˆู‡ู… ุจุฌู…ู„ ูˆ ูŠุชุจุญูˆู‡ุŒ ูู‡ูˆ ุฒูŠ ู…ูˆุตูŠุจุฉุŒ ุฑุงุญ ุฌู…ู„ู‡
355
00:31:13,200 --> 00:31:17,760
ูˆ ุฑูƒูˆุจู‡ ุจุชุงุนุชู‡ุŒ ู„ูƒู† ู‡ู… ุงุณุชูุฏูˆุง ูˆ ุฃูƒู„ูˆุง ู„ุญู… ุชู„ุช
356
00:31:17,760 --> 00:31:24,500
ุงุฑุจุน ุงูŠุงู… ุงูˆ ุฎู…ุณ ุงูŠุงู…ุทูŠุจุŒ ูŠุจู‚ู‰ ุงู„ู€ Antibiotics
357
00:31:24,500 --> 00:31:32,020
ุงู„ุฃู‚ู„ ุชุฏุงูˆู„ู‹ุง ู„ู„ู€ Systemic Use ู‡ูŠ ุงู„ุฃูุถู„ ู„ู„ุนูŠู†ุŒ
358
00:31:32,020 --> 00:31:38,340
ูƒูˆูŠุณุŸ Although some antibacterials are marketed as
359
00:31:38,340 --> 00:31:41,040
simple ophthalmic preparations containing just one
360
00:31:41,040 --> 00:31:43,820
active ingredient, many preparations contain
361
00:31:43,820 --> 00:31:49,530
eitherAntibacterias or Asteroids and Antibiotics
362
00:31:49,530 --> 00:31:53,510
ูŠุนู†ูŠ ุงู„ุฃู† ุชูู†ู†ูˆุง ุญุชู‰ ุจุฏู„ ุฃู† ูŠุญุทูˆุง ู†ู‚ุทุฉ ู…ุถุงุฏุฉ ุญูŠูˆูŠุฉ
363
00:31:53,510 --> 00:31:59,650
ูŠุญุทูˆุง ุงุชู†ูŠู† ุงุณุชูŠุฑูˆูŠุฏ ุจู‚ู‰ุŸ ุฃู‡ ู„ุฃ ูˆููŠ Antibiotics ููŠ
364
00:31:59,650 --> 00:32:03,490
Antibiotics ุงุชู†ูŠู† ุฃูˆ ุชู„ุฃ ูŠุนู†ูŠ ู…ุซู„ุง ู‚ุทุฑุฉ ุงู„
365
00:32:03,490 --> 00:32:06,010
Maxitrol ุงู„ู„ูŠ ููŠ ุงู„ุณูˆู‚ ู…ู„ูŠุงู†ุฉ ููŠ ุงู„ุณูˆู‚ ุงุณู…ู‡ุง
366
00:32:06,010 --> 00:32:09,230
Maxitrol ููŠู‡ุง Two Antibiotics
367
00:32:14,720 --> 00:32:18,320
ู„ุฃ ููŠ ู‚ุทุฑุงุช ููŠู‡ุง three antibiotics ูŠุนู†ูŠ ู…ูˆู„ุง ููŠ
368
00:32:18,320 --> 00:32:21,680
ุงุชุญุงุฏ ุงุชุญุงุฏ ุงุชุญุงุฏ ู†ู‚ุทุฉ ุญุท ููŠู‡ุง ูŠุนู†ูŠ ุงูƒุชุฑ ู…ู†
369
00:32:21,680 --> 00:32:25,240
antibiotic ุฎุงุตุฉ ููŠ ุญุงู„ุงุช ุงู„ุฎุทูŠุฑุฉ ุฎุงุตุฉ ููŠ ุงู„ุญุงู„ุงุช
370
00:32:25,240 --> 00:32:31,240
ุงู„ุฎุทูŠุฑุฉ ูˆู‡ุฐุง ูŠุนู†ูŠ ุงูŠุด ุฒูŠุงุฏุฉ ููŠ ุงู„ูุงูŠุฏุฉ ู„ู„ู…ุฑูŠุถ
371
00:32:33,970 --> 00:32:37,170
ู‚ุณู…ูˆุง ุงู„ู…ุฌู…ูˆุนุงุช ุงู„ู„ูŠ ุชุณุชุฎุฏู… ููŠ ุนู„ุงุฌ ุงู„ุนูŠู† ูƒ
372
00:32:37,170 --> 00:32:40,930
Antibiotics Beta Leptams ู…ุฌู…ูˆุนุฉ ุงู„ุจู†ุณูŠู†ูŠุฉ ุจุชุงุนูƒ
373
00:32:40,930 --> 00:32:45,130
ุงู„ุนุตู„ูŠุฉ ูู‡ูŠ ุงู„ุจู†ุณูŠู†ูŠู† ุงู„ู„ูŠ ู‚ุจู„ ู…ุฆุฉ ุณู†ุฉ ุชู‚ุฑูŠุจุง
374
00:32:45,130 --> 00:32:50,310
ุงุณู…ู‡ุง Beta Leptams ูˆู‡ู†ุง ุชุชุฑู‰ Cyclins ุงู„ุชุฑู…ูŠุณูŠู†ุงุช
375
00:32:50,310 --> 00:32:58,690
ูˆู‡ู†ุง Macrolides ุงู„ู…ุฌู…ูˆุนุงุช ุงู„ู„ูŠ ู‡ูŠ ุงู„ุชุฑู…ูŠุณูŠู† ูˆ ุงู„
376
00:32:58,690 --> 00:33:02,680
generations ุจุชุงุนุชู‡ู… ุงู„ุชุฑู…ูŠุณูŠู†Chloramphenicols
377
00:33:02,680 --> 00:33:08,780
ู…ุฌู…ูˆุนุฉ Fluoroquinolones ู…ุฌู…ูˆุนุฉ ุงู„ู€ Oflox ูˆุงู„ุฒูŠู…ุฑ
378
00:33:08,780 --> 00:33:13,060
ูˆุงู„ุญูŠุงุช ู‡ุฐู‡ ุญุฏูŠุซุฉ ุทุจุนุง ุญุฏูŠุซุฉ ุฃุญุฏุซ ุดูŠุก Amino
379
00:33:13,060 --> 00:33:17,900
glycosides ู…ุฌู…ูˆุนุฉ ุงู„ุฌูŠู† ุงู„ุชู…ุงูŠุณูŠูŠู† ูˆุงู„ุฃุจุฌูŠู†
380
00:33:17,900 --> 00:33:22,200
ูˆุงู„ุญูŠุงุช ู‡ุฐู‡ ุซู… ุณุงู„ูุฉ ู…ุฌู…ูˆุนุฉ ุงู„ุณุงู„ูุฉ ุงู„ุขู† obsolete
381
00:33:22,200 --> 00:33:24,680
ู…ุณุชุฎุฏู…ุงุช ูŠุนู†ูŠ ูƒุงู† ุฒู…ุงู† ู…ู‡ู…
382
00:33:32,190 --> 00:33:36,250
ู„ูˆ ุงุชูƒู„ู…ู†ุง ุนู„ู‰ ุงู„ beta-lactam ุจุงุฎุชุตุงุฑ beta-lactams
383
00:33:36,250 --> 00:33:41,370
ู‡ุฐู‡ ุงู„ุจู†ุณูŠุฑูŠู†ุฉ ู…ุฌู…ูˆุนุฉ ุงู„ุจู†ุณูŠุฑูŠู† ุงู„ุฃุตู„ูŠ ุงู„ beta
384
00:33:41,370 --> 00:33:46,450
-lactams ููŠู‡ ring ูŠุนู†ูŠ ู‡ูŠ ุงู„ู„ูŠ ุนู„ูŠู‡ุง ุงู„ุณู‡ู… ุนุดุงู†
385
00:33:46,450 --> 00:33:51,670
ู‡ูŠูƒ ุงู„ ring ู‡ุฐู‡ beta ring lactam ring ูุณู…ูˆู‡ุง ุจู†ุงุก
386
00:33:51,670 --> 00:33:51,990
ุนู„ู‰
387
00:33:56,310 --> 00:34:00,310
ุจูŠุงุฎุฏ ุฃูˆ ุจูŠุญุชูˆูŠ ุนู„ู‰ Beta-Lactam ุณู…ูˆู‡ ููŠ ุงู„ู…ุฌู…ูˆุนุฉ
388
00:34:00,310 --> 00:34:04,870
ู‡ุฐู‡ ูˆู‡ูŠ ุงู„ู€ Benzaline ูˆู…ุดุชู‚ุงุชู‡ ุทุจุนุง ุงู„ู€ Brocaine
389
00:34:04,870 --> 00:34:11,030
Benzaline ุงู„ุฃุตู„ูŠ ุงู„ู„ูŠ ุญุชู‰ ุงู„ุขู† injectable ุงุดุชู‚ ู…ู†ู‡
390
00:34:11,030 --> 00:34:17,690
ุนุฏุฉ ู…ุดุชู‚ุงู† ุญุชู‰ ุฅู†ู‡ุง ูƒุฏู‡ ู‚ูˆู„ ูŠุนู†ูŠ ุจุงู„ุนุดุฑุฉ Benzaline
391
00:34:17,690 --> 00:34:21,770
ูƒุฏู‡ Benzaline ูƒุฏู‡ ู…ุถุงุฏู„ุฉ ูƒุฏู‡ Benzaline ูŠุนู†ูŠ ููŠ
392
00:34:21,770 --> 00:34:27,500
ุงู„ุชุฑูƒูŠุจ ุงู„ูƒูŠู…ูŠุงุฆูŠ ุจุชุงุน Benzalineุฃุถููˆู„ู‡ ุฐุฑู‘ุงุฑ ูˆ
393
00:34:27,500 --> 00:34:34,180
ุฌุฐุฆุงุจ ูุฃุตุจุญ ููŠ ู…ู†ู‡ ุฃุดูŠุงุก ูƒุซูŠุฑุฉ ูู…ุซู„ุง ู…ุง ู…ู†ูƒู… ุฅู„ุง
394
00:34:34,180 --> 00:34:40,980
ู…ุซู„ุง ู…ุงุฑูˆุฑ ู…ุน ุงู„ .. ุงู„ ุฃู…ูˆ ุจุฐูƒูŠุฑ ู…ุซู„ุง ุฃู…ูˆ ุจุฐูƒูŠุฑ
395
00:34:40,980 --> 00:34:46,960
ู‡ู†ุง ููŠ ุงู„ุณูˆูŠุฉ ูŠุนู†ูŠ ู‡ูˆ .. ูŠุนู†ูŠ ูƒู…ุงู† ูƒู„ู…ุฉ ุจู‚ู‰ ุน ุงู„
396
00:34:46,960 --> 00:34:51,380
.. ู„ู…ูˆู† ูˆุฑุจุน ุฃุดู‡ุฑ ุดูƒู„ ุงู„ุนู„ู…ุงุก ุฃู…ูˆ ุจุฐูƒูŠุฑ ู‡ุฐุง ุฅุญุฏู‰
397
00:34:51,380 --> 00:35:00,260
ุงู„ู…ุดุชู‚ุงุช ูุชุงู„ ุงู„ุจู†ุณุฉ ุฏูŠุจุนุฏูŠู† ุทูˆุฑูˆุง ู…ู†ู‡ ู„ูุธุฉ ุณู„ู†
398
00:35:00,260 --> 00:35:06,540
ุฃู…ุจูŠ ุณู„ู† ุฃู…ูˆุฒ ุณู„ู† ูˆุงู† ุฃู…ูˆุฒ ูƒุชุฑ ุฃู…ุจูŠ ุณู„ู† ุจูุฑ ุณู„ู†
399
00:35:06,540 --> 00:35:10,920
ุทูˆุฑ ูˆุงู† ุฃู…ุจูŠ ูƒุชุฑ ู„ูƒู† ุฃู†ุง ุจู‡ู… ู…ุซู„ ุขุฎุฑ ุฅูŠุด ุงุณุชุฎุฏุงู…ู‡
400
00:35:10,920 --> 00:35:15,060
ููŠ ุงู„ุนูŠู†ุŸ ูŠุนู†ูŠ ู‡ุฐุง systemicุŸ ุฃู‡ุŒ ูƒูˆูŠุณุŒ ู„ูƒู† ุฅูŠุด
401
00:35:15,060 --> 00:35:21,940
ุงุณุชุฎุฏุงู…ู‡ ููŠ ุงู„ุนูŠู†ุŸ ููŠ ุงู„ุนูŠู† ุจูŠู‚ูˆู„ ู„ูŠู‡ุŸ ูุงู„ุณู„ู† pass
402
00:35:21,940 --> 00:35:23,500
across the ocular
403
00:35:27,460 --> 00:35:36,980
ู…ูˆุฑู„ูŠ ู„ู„ุฃุณูุŒ ุฅูŠุด ููŠ ุงู„ barriersุŸ ูƒูˆุฑูŠุงุŒ
404
00:35:36,980 --> 00:35:38,060
ูˆ ุณูƒู„ูŠุฑุง
405
00:35:47,650 --> 00:35:52,690
ุจู„ุงุฏ ุงูŠุดุŸ ุจุชุงุนุชู†ุง ุงู„ barrier ูˆ ุจู„ุงุฏ ุงูŠุดุŸ ุจุฑุงูŠุฑ ุงู„
406
00:35:52,690 --> 00:35:57,790
barrier ู„ุฃ ู…ุด ุจุฑุงูŠุฑ ู„ุฃุดุชุบู„ู†ุง ููŠ ุงู„ brain ููŠ ุงู„ู‚ุฑุงุฑ
407
00:35:57,790 --> 00:36:01,490
ูˆ ููŠ ุงู„ iris ูˆุดูŠุก ูƒู„ ู‡ุฐู‡ barriers ุทูŠุจ ูุจู‚ูˆู„ูŠ ูŠุง
408
00:36:01,490 --> 00:36:05,490
ุฑูˆุญ ุนุจุฑ ู‡ุฐู‡ ุงู„ barriers very poor and products
409
00:36:05,490 --> 00:36:08,750
containing them are rarely used in the treatment
410
00:36:08,750 --> 00:36:12,170
of ocular infections ูŠุนู†ูŠ ุฃู†ุง ุงู„ุญู…ุฏ ู„ู„ู‡ ุฅูŠู„ูŠ ููŠ
411
00:36:12,170 --> 00:36:18,950
ุงู„ููŠู„ ุจุงู„ู‚ู„ูŠู„ ู…ู† ุนุดุฑูŠู† ุณู†ุฉู„ู… ู†ุณุชุฎุฏู… ู‚ุทุฑุฉ ุจู†ุณุฑูŠู† ุฃูˆ
412
00:36:18,950 --> 00:36:23,830
ู…ุดุทู‚ุงุชู‡ ูˆู„ุง ู…ุฑุญุจ ุจู†ุณุฑูŠู† ุฃูˆ ู…ุดุทู‚ุงุชู‡ ุนุดุงู† ู‡ุฐุง ุงู„ุณุจุจ
413
00:36:23,830 --> 00:36:28,430
ูŠุจู‚ู‰ ุจู†ุณุฑูŠู† ุจูŠุจู‚ู‰ ู„ู‡ู… systemic use ู„ูƒู† ุงู„ local
414
00:36:28,430 --> 00:36:34,350
use ููŠ ุงู„ุนูŠู† ููŠ ุนู†ุฏู‡ู… ู…ุดูƒู„ุฉ ู…ุด ู…ููŠุฏุฉ ูƒุชูŠุฑ ุฑุงุญูˆุง
415
00:36:34,350 --> 00:36:38,450
ุทุจุนุง ุจุนุฏ ู‡ูŠูƒ ุชุชุฑุง cyclines ุชุชุฑุง cyclines ู‡ุฐู‡
416
00:36:38,450 --> 00:36:45,240
family ูƒุจูŠุฑุฉ ููŠ ู…ู†ู‡ุง ุนุฏูŠุฏ ู…ู† ุฃุนุถุงุกูู…ุซู„ู‹ุง broad
417
00:36:45,240 --> 00:36:51,220
spectrum ูˆุณุท ุงู„ .. ุงู‡ chlor .. ุงู‡ chlor
418
00:36:51,220 --> 00:36:56,340
tetracyclines ูˆ ุฏูŠ ู…ูŠู‡ุŸ ุฏูŠ ู…ุซุงู„ chlor tetracycline
419
00:36:56,340 --> 00:37:01,900
ูˆ oxytetracycline ูˆ tetracycline ุจุนุฏ ูˆ doxycycline
420
00:37:01,900 --> 00:37:07,000
ูˆ ุงู†ุฌู„ุงู†ุฏุฑ ู…ุด ุงู†ุช ุฎุฏุช ุฏูˆูƒุฏุง ุณูŠู„ูŠู†ุŸ ุฏูˆูƒุฏุง ุณูŠู„ูŠู† ู‡ูˆ
421
00:37:07,000 --> 00:37:11,770
ู‡ุฐุงู…ุฌู…ูˆุนุงุช ุงู„ุชุฑุงู…ูŠุณูŠู† ุจุณ ุทูˆุฑูˆุง ุนู„ู‰ ุงู„ู…ุฌู…ูˆุนุฉ
422
00:37:11,770 --> 00:37:16,350
ุงู„ุฃุณุงุณูŠุฉ ู„ู„ุชุชุฑุง ุณุงูŠูƒู„ูŠู† ูˆ ุญุทูˆู„ู‡ ุชูุถุณูŠู„ูŠู† ุณู†ุฉ ูˆุชุงุฎุฑ
423
00:37:16,350 --> 00:37:20,570
once daily which has a broader spectrum and more
424
00:37:20,570 --> 00:37:26,510
specific ู„ู‡ูˆ indications ุทูŠุจ
425
00:37:26,510 --> 00:37:29,670
ุชุชุฑุง ุณุงูŠูƒู„ูŠู† are effective against gram positive
426
00:37:29,670 --> 00:37:33,270
and gram negative ุจูƒุชูŠุฑูŠุง ูŠุดุชุบู„ ุนู„ู‰ gram positive
427
00:37:33,270 --> 00:37:36,390
ูˆ gram negative ูˆู‡ุฐุง ุงุญู†ุง ุจูŠู‚ูˆู„ู†ุง broad spectrum
428
00:37:37,470 --> 00:37:42,710
ู„ู…ุง ู…ุถุงุฏ ุญูŠูˆูŠ ุจูŠุดุชุบู„ ุจุณ ุนู„ู‰ ุงู„ gram positive ุฃูˆ ุจุณ
429
00:37:42,710 --> 00:37:45,410
ุนู„ู‰ ุงู„ gram negative ุจูŠู‚ูˆู„ ุนู†ู‡ narrow spectrum
430
00:37:45,410 --> 00:37:51,150
antibiotic ู„ูƒู† ู„ู…ุง ุจูŠูƒูˆู† ุจูŠุดุชุบู„ ุนู„ู‰ gram positive
431
00:37:51,150 --> 00:37:56,030
and gram negative ุจูŠูƒูˆู† ุจูŠุดุชุบู„ ุนู„ู‰ ู…ุฆุงุช ุฃู†ูˆุงุน ู…ู†
432
00:37:56,030 --> 00:37:57,110
ุงู„ุจูƒุชูŠุฑูŠุง ุจูŠู‚ูˆู„ ุนู†ู‡
433
00:38:01,090 --> 00:38:05,330
ุทูŠุจ ุจูŠู‚ูˆู„ ุงู„ู„ูŠ ุงู„ tetracycline ู…ุด ุจุณ ุจูŠุดุชุบู„ ุนู„ู‰
434
00:38:05,330 --> 00:38:08,910
ุงู„ุจูƒุชูŠุฑูŠุง ุจู„ ุจูŠุดุชุบู„ ุนู„ู‰ ุงู„ spiral case ูˆุนู„ู‰
435
00:38:08,910 --> 00:38:13,010
ุงู„ูƒู„ูŠุงู…ูŠุฏูŠุง ุงู„ู„ูŠ ุจุชุนู…ู„ ุงู„ trachoma ูˆุนู„ู‰ ุฃุฎุฑ ุงู„
436
00:38:13,010 --> 00:38:16,530
organisms ูŠุนู†ูŠ ูƒู…ุงู† ูˆุตู„ุฉ type 1 ุฃูƒุชุฑ ู…ู† ุงู„ุจูƒุชูŠุฑูŠุง
437
00:38:16,530 --> 00:38:22,310
ุฃุดูŠุงุก ุฃุฎุฑู‰ resistance ุจูŠู‚ูˆู„ูˆุง ุงู„ุจูƒุชูŠุฑูŠุง ุงู„ ground
438
00:38:22,310 --> 00:38:25,530
negative ุงู„ู„ูŠ ุงุณู…ู‡ุง Sodomorus Sodomorus ุฎุทูŠุฑุฉ ุฌุฏุง
439
00:38:25,530 --> 00:38:27,270
ู‡ูŠ ุจุชุนู…ู„ colon ulcer
440
00:38:30,930 --> 00:38:36,570
ุงู„ู‡ูŠู„ูˆ ุจูŠู‚ุฏุฑุด ุนู„ูŠู‡ุง ูˆ ุงู„ุจุฑูˆุชูŠุงุณ ุจุฑุถู‡ ุจุชุนู…ู„ ูƒูˆุฑู†
441
00:38:36,570 --> 00:38:42,450
ุงู„ุฃู„ุซู„ ุจุฑุถู‡ ู…ุงุจูŠู‚ุฏุฑุด ุนู„ูŠู‡ุง ู„ูƒู† ุจุงู‚ูŠ ุงู„ุจูƒุชูŠุฑูŠุง
442
00:38:42,450 --> 00:38:46,550
ุงู„ุนุงุฏูŠุฉ ุจุชุงุนุฉ ุงู„ congenitivites ูˆ ุฅุดูŠ ู‡ูŠ ูƒูˆูŠุณุฉ
443
00:38:46,550 --> 00:38:53,110
side effects ุณูŠุณุชุงู†ูŠูƒ ุจูŠุนู…ู„ ุงู„ stomach upset ุทุนู…
444
00:38:53,110 --> 00:38:56,430
ู…ุชุนุจ ูˆูŠู† ููŠ ุงู„ู…ุฏู‰ ู‡ุฐุง ุณูŠุณุชุงู†ูŠูƒ ู„ูˆ ุฃุฎุฏู†ุง ูƒุฑุณูˆู„ุฉ
445
00:38:56,430 --> 00:39:03,000
ู†ูˆุฒูŠุง ูˆ vomiting on ุฏูŠุงุฑูŠุฉูู„ูˆ ุฃุฎุฏู†ุง ูƒุงุจุณูˆู„ุงุช ูˆ
446
00:39:03,000 --> 00:39:09,240
ูƒู…ุงู† ู„ูˆ ุฃุฎุฏู†ุง ูƒุงุจุณูˆู„ุงุช ู…ู…ูƒู† ูŠุนู…ู„ ุนู„ู‰ ุฃุณู†ุงู† ุงู„ุฃุทูุงู„
447
00:39:09,240 --> 00:39:18,120
ุชู„ูˆู† ุจุฑุชู‚ุงู„ูŠ ุฃูˆ ุฃุตูุฑ ูŠุชุฑุณุจ ููŠ ู‡ุถุงู… ุงู„ุฃุทูุงู„ ูˆ ู‡ุถุงู…
448
00:39:18,120 --> 00:39:24,840
ุงู„ุญูˆุงู…ู„ they permanently color teeth yellow and
449
00:39:24,840 --> 00:39:31,390
show bone growthุงู„ุนูŠู†ุง ูŠุจุทุฆ ู…ู† ู†ู…ูˆ ุงู„ุฃุนุถุงุก ููŠ
450
00:39:31,390 --> 00:39:35,970
ุงู„ุฃุทูุงู„ ุจุณุจุจ ู‚ุฏุฑุงุช ูƒุงู„ุณูŠูˆู… ุงู„ู…ุบู†ูŠุฒูŠูˆู… ูŠุชุญุฏ
451
00:39:35,970 --> 00:39:40,750
ุจุงู„ูƒุงู„ุณูŠูˆู… ุงู„ู…ุบู†ูŠุฒูŠูˆู… ูˆูŠู…ู†ุนู‡ู… ู…ู† ุฃู† ูŠูƒูˆู†ูˆุง ู…ุฏุจุฒุดูŠู†
452
00:39:40,750 --> 00:39:44,990
ููŠ ุงู„ุจูˆู† ููŠ ุจู†ุงุก ุงู„ุจูˆู† ุนุดุงู† ู‡ูŠูƒ Contra-indicated
453
00:39:44,990 --> 00:39:50,990
ููŠ ุงู„ุฃุทูุงู„ ูˆููŠ ุงู„ุญูˆุงุจู„ ุนุดุงู† ูŠุฎุด ููŠ ุฃุนุถุงุก ุงู„ุฌู†ูŠุฏ
454
00:39:50,990 --> 00:39:55,490
ุงู„ุจุฑุฌ ุงู„ fix from topical application ู†ุฌูŠ ู„ู„ุนูŠู†
455
00:39:55,490 --> 00:40:02,630
ู„ุนูŠู†ุจู‚ูˆู„ ุงู† ุงู„ู‚ุทุฑ ููŠ ุงู„ุนูŠู† ู‚ุฑุฑ ู…ุงููŠุด ุญุฏุงุช ููŠ ุงู„ุนูŠู†
456
00:40:02,630 --> 00:40:08,290
ูŠุนู†ูŠ ู†ุงูŠุจู‡ุง ุนู„ูŠู‡ due to the slow dose of the drug
457
00:40:08,290 --> 00:40:11,730
ูŠุนู†ูŠ ุงุญู†ุง ุงู†ุง ู‚ุทุฑ ุจู‚ูˆู„ูƒ ูˆุงุญุฏ ููŠ ุงู„ู…ูŠุฉ ุชุชุฑุง ุณุงูƒู„ูŠู†
458
00:40:11,730 --> 00:40:19,770
ู‚ุทุฑุฉ ูˆู„ุง ู‡ุชุนู…ู„ ุฌุฏ ูƒุงุจุณูˆู„ุฉ ููŠ ุฎู„ุงู„ ุงุฑุจุน ุงุด ุฃุดู‡ุฑ
459
00:40:19,770 --> 00:40:25,610
ูŠุนู†ูŠ ุงู†ุง ู‚ุทุฑ ุงู„ุชุชุฑุง ุณุงูƒู„ูŠู† ููŠ ุงู„ุนูŠู† ู…ุฏุช ุงุฑุจุน ุฃุดู‡ุฑ
460
00:40:27,450 --> 00:40:32,170
ุงู„ุฌูˆุนุฉ ุชุณุงูˆูŠ ูƒุฑุณูˆู„ุฉ ู‡ุฐุง ููŠู…ุง ูŠุชุนู„ู‚ ุจุงู„ู€ Systemic
461
00:40:32,170 --> 00:40:38,770
ููŠุนู†ูŠ ู…ุงููŠุด ู…ู† ุงู„ุฎูˆู ู„ูƒู† ุงู„ุญู‚ูŠู‚ุฉ ุงู† ุงู„ penetration
462
00:40:38,770 --> 00:40:42,670
across the intact cornea is poor and these
463
00:40:42,670 --> 00:40:46,190
compounds are best used for surface infections as
464
00:40:46,190 --> 00:40:51,510
ointment ูŠุนู†ูŠ ููŠ ู…ุฑุญู… ุงู„ุชุฑู…ูŠุณูŠูŠู† ูˆุงู„ุฌุฑุฏุฑุณูŠูƒู„ูŠูŠู†
465
00:40:51,510 --> 00:40:55,930
ูˆุงู„ุบูˆุฒูŠุณูŠูŠู† ูƒู„ ู‡ุฐู‡ ูƒุงู†ุช ุจุณ ูƒู†ุฏุฑุฉ ุทูŠุจุฉ ุงู„ infection
466
00:40:56,860 --> 00:41:02,140
ูˆุงู„ู€ Blepharitis ูˆ Lid Infection ูˆ ุงู„ูƒู„ุงู… ุฏู‡ ู„ูƒู†
467
00:41:02,140 --> 00:41:06,660
ู…ุด ู„ูŠู‡ ุนู„ุงุฌ ุงู„ Intraocular Infection ูˆู„ุง ุญุชู‰
468
00:41:06,660 --> 00:41:11,980
Keratitis ูƒูˆูŠุณุŸ ุงู†ู‡ ู…ูˆุฌูˆุฏ Gordacycline ูˆ Teramycin
469
00:41:11,980 --> 00:41:13,320
ู…ุด ู‡ูˆ Teramycin ุงู„ู…ุฑู…ู‰
470
00:41:44,540 --> 00:41:52,300
ุงู„ุญุฏูŠุซ ุงู„ูˆู„ุงู†ุง ุงู„ุฐูŠู† ู†ุฒู„ูˆุง ู…ูุชู‡ุงุจุงุช ููŠ ุงู„ู…ู„ุชุญู‚
471
00:41:52,300 --> 00:41:58,480
ุงู„ูˆูˆู„ุงู†ุง
472
00:41:58,480 --> 00:42:06,680
ุงูˆู„ ู…ุงู„ุทู ูŠูˆู„ุฏ ููŠ ุงู„ุณุงุนุฉ ุงู„ุฃูˆู„ู‰ ุชุฌูŠ ุงู„ู†ุงุณุชุบุณู„
473
00:42:06,680 --> 00:42:13,180
ุนูŠู†ูŠู‡ ุจุตุฑุงูŠู‡ ุชุดูู‡ู… ูˆ ุชุถุน ู„ู‡ู… ู…ุฑู‡ู… ุชุฑู…ูŠุณูŠู† ููŠ
474
00:42:13,180 --> 00:42:18,580
ุงู„ุตุจุงุญ ูˆ ููŠ ุงู„ู…ุณุงุก ู‡ุฐุง profile axis ู„ูˆ ูˆู„ุฏ ู„ู‡ู…
475
00:42:18,580 --> 00:42:25,920
ุนู†ุฏู‡ุง ุชู„ูˆุฑ ููŠ ู…ุฌุงุฑูŠ ุงู„ูˆู„ุงุฏุฉ ุงูƒุชุฑ ุงูƒุชุฑ ู‡ุฐุง ูŠู…ู†ุน ุงู†ู‡
476
00:42:25,920 --> 00:42:31,980
ุชุทูˆุฑ ุงู„ infection ุชุทูˆุฑ ุงู„ infection ููŠ ุงู„ 83
477
00:42:35,270 --> 00:42:43,630
ูˆ ุฑูˆุด ูˆ ู†ูŠูˆุฑ ุชูˆุฑ ุงูŠุถุง ุงู‚ุชู†ุน ุงู†ุชุฑุงู…ุณุจุฑุจู†ุณูŠู„ูŠู† ูˆ
478
00:42:43,630 --> 00:42:49,030
ุชุชุฑุงุณุงูƒู„ูŠูŠู† 1% ูƒู…ุดุฑูˆุน ุจุฑูˆููŠู„ุงูุชูƒ ูŠุนู†ูŠ ู‚ุงู„ ุงู‡ ุงุนุทูŠ
479
00:42:49,030 --> 00:42:53,910
ุงู„ุฃู… ุญู‚ู†ุง ููŠ
480
00:42:53,910 --> 00:42:58,390
ุงู„ุนุถู„ ููŠู‡ุง ุจู†ุณู„ูŠู† ูˆ ุชุชุฑุงุณุงูƒู„ูŠูŠู† ุนุดุงู† ู„ูˆ ูˆู„ุฏ
481
00:42:58,390 --> 00:43:04,240
ุงู„ู…ูˆู„ูˆุฏ ุจุงู„ุฐู‡ุงุจ ุงู†ู‡ ู…ุงูŠูู„ุด ููŠู‡ุฅุฐุง ูƒุงู†ุช ุงู„ุงู†ููƒุงุฑูŠุฉ
482
00:43:04,240 --> 00:43:11,040
ูƒู„ูŠุงู…ูŠุฏูŠุง ุฒูŠ ุงู„ุชุฑุงูƒูˆู…ุฉุŒ ูุงู„ุชุฑุงุซูŠูƒู„ูŠุช ุชุฑูŠุชู…ู†ุช ูŠุนู†ูŠ
483
00:43:11,040 --> 00:43:13,500
ู…ุฑู‡ู… ู‡ูˆ ุฃู† ูŠุชู… ุชุฌุงุฑุจู‡ ุนู„ู‰ ุฃุฎุฑู‰
484
00:43:13,500 --> 00:43:32,060
ุงู„ุงู†ุชูŠุจูˆูŠุชูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠูƒูŠ
485
00:43:36,430 --> 00:43:39,850
ู‡ูˆ ุงูƒุซุฑ ู…ู† ุงูŠ ุงู†ุชูŠุจุงุชูŠูƒ ุงุฎุฑ