passages.id: split_4_test_2250_passage
passages.type: progene_text
passages.text: Only one patient showed no significant change , whilst nine exhibited significant reductions of FMZ binding in at least one ROI ( 3 x 1 , 4 x 2 , 1 x 3 , 1 x 4 ) , and significant increases were observed in two ROIs of another patient .