passages.id: split_4_test_1074_passage
passages.type: progene_text
passages.text: Within the group of 40 H1069Q - homozygous patients , the onset of symptoms was significantly delayed in patients with the ApoE epsilon3 / 3 genotype ( 25 +/- 6 years at presentation ) compared with patients with the ApoE epsilon3 / 4 genotype ( 20 +/- 3 years at presentation ) .