passages.id: split_4_test_1094_passage
passages.type: progene_text
passages.text: Blood was collected on Weeks 0 , 2 , 4 , 8 and 12 to assess the following : (1) mitogen - induced peripheral blood mononuclear cells ( PBMCs ) proliferation , ( 2 ) changes in PBMC subpopulations , ( 3 ) interleukin-2 ( IL-2 ) production and ( 4 ) plasma immunoglobulin ( Ig ) G production .