passages.id: split_4_test_3185_passage
passages.type: progene_text
passages.text: Microinjection bilaterally of Mev ( 10 nmol ) into the RVLM induced progressive hypotension and minor bradycardia , alongside significant depression of the activity of NADH cytochrome c reductase ( enzyme marker for Complexes I and III ) or cytochrome c oxidase ( enzyme marker for Complex IV ) in the mitochondrial respiratory chain , reduction in ATP concentration , or tissue hypoxia in the RVLM .