passages.id: split_4_test_3398_passage
passages.type: progene_text
passages.text: Our studies show an interface characterized by a protruding antibody - combining site centered on the long heavy chain CDR3 loop of Fab b96.11 establishing interactions with the critical residue Phe(344) in the core of the epitope on GAD65 , surrounded by charged sites within ( 375 ) RK ( 376 ) and ( 305 ) DER ( 307 ) .