passages.id: split_4_test_3323_passage
passages.type: progene_text
passages.text: In addition , transfection of icIL-1ra1 in HeLa cells did not cause inhibition of IL-8 promoter activity following over - expression of the IL-1 signalling components MyD88 , IRAK-1 , TRAF-6 , Ikappakappabeta or RelA .