passages.id: split_4_test_2539_passage
passages.type: progene_text
passages.text: In contrast , the bona fide PPARgamma ligands ( TZDs ; rosiglitazone , pioglitazone and troglitazone ) barely inhibited proinflammatory cytokines , but strongly enhanced the production of IL-1Ra from PMA - stimulated THP-1 cells .