passages.id: split_4_test_1810_passage
passages.type: progene_text
passages.text: Synaptic location of protease - activated , G-protein - coupled receptors ( PARs ) for thrombin and related proteases , their serpin and Kunitz - type PIs such as protease nexin I ( PNI ) , alpha1 - antichymotrypsin ( alpha - ACT ) , and the Kunitz protease inhibitor ( KPI ) - containing secreted forms of beta - amyloid protein precursor ( beta-APP ) , along with the TGases and their putative substrates , have all been amply documented .