passages.id: split_4_test_2673_passage
passages.type: progene_text
passages.text: These results provide proof - in - principle that anti - hCyclinT1 intrabodies can be designed to block HIV-1 replication without causing cellular toxicity , and as a result , they may be useful agents for " intracellular immunization " - based gene therapy strategies for HIV - 1 infection / AIDS .