passages.id: split_4_test_102_passage
passages.type: progene_text
passages.text: However , in the JB6 ( 41 P+) promotable cell line , C3H10T1 / 2 and B16 melanoma cells , where BPO was less cytotoxic , it did not readily inactivate PKC due to a rapid reversibility of this inactivation by an endogenous mechanism .