passages.id: split_4_test_1852_passage
passages.type: progene_text
passages.text: The findings showed that ( 1 ) while multiple diverse mucin genes were expressed in the biliary epithelium , MUC3 and MUC5B mRNA were the main mucin genes expressed in the biliary epithelium of stone - containing intrahepatic bile ducts and normal controls ; ( 2 ) absent or decreased expression of MUC2 , MUC3 , and MUC5B of mRNA was found in cholangiocarcinomas in contrast to nonneoplastic biliary epithelium ; and ( 3 ) increased expression of MUC4 and MU5AC of mRNA was found in cholangiocarcinomas and the biliary epithelium , especially for dysplastic cells of stone - containing intrahepatic bile ducts compared with normal controls .