passages.id: split_4_test_2868_passage
passages.type: progene_text
passages.text: When hepatocytes were stimulated with IFN-gamma or cytokine mixture ( IFN-gamma , interleukin-1beta and tumour necrosis factor - alpha ) , c-Jun N - terminal kinase ( JNK ) , p38 and extracellular - regulated kinase ( ERK ) were phosphorylated , suggesting an involvement of the mitogen - activated protein kinases ( MAPK ) in the induction of mob-1 expression .