passages.id: split_7_validation_166_passage
passages.type: progene_text
passages.text: The aim of the present study was to test with a whole blood culture system if hyperlipoproteinemia is associated with increased cytokine production capacity in these patients and if treatment with 3-hydroxy-3-methylglutaryl coenzyme A ( HMG-CoA ) reductase inhibitors influences this production capacity of blood cells , at both the protein and mRNA levels .