passages.id: split_7_validation_1542_passage
passages.type: progene_text
passages.text: Although the risk of malformation in children born after ICSI is not increased there is an increased risk to transmit genetic abnormalities in case of NOA ( such as the rate of sex chromosome , or microdeletions of the Y chromosome ) and in case of congenital OA ( mutations of the cystic fibrosis gene ) .