passages.id: split_9_validation_424_passage
passages.type: progene_text
passages.text: Nevertheless , the tyrosine phosphorylated sequence ( IKKpYRLQ ) bound specifically to the SH2 domain proximal to the NH(2) - terminal of SHP-2 ( SHP-2 - N ) but not to the SH2 domain proximal on the COOH - terminal side ( SHP-2 - C ) .