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The efficacy and safety of upadacitinib as compared...', 'thumbnail': 'https://serpapi.com/searches/6721b155adc33bdf8466fd27/images/43cbb0de0312136cddb98b91e28de571c201b1535deb68c5f04ea81c2fdd614c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.876733124256134}",,,,,,,,,,['neutral'],neutral,1 NCT02192424,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-40287-w', 'title': 'Determinants of sustained stabilization of beta-cell function following short-term insulin therapy in type 2 diabetes', 'source': 'Nature', 'date': 'Jul 27, 2023', 'snippet': 'In early type 2 diabetes, the strategy of “induction” with short-term \nintensive insulin therapy followed by “maintenance” with metformin can...', 'thumbnail': 'https://serpapi.com/searches/6721b1825416d8e6ac1cfa69/images/5ff7ffb3cb20167878647571d036c8103b24ace0f66d617ee07ddac6cdaac77f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8652159571647644}",,,,,,,,,,['neutral'],neutral,1 NCT04886596,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209604', 'title': 'Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults', 'source': 'The New England Journal of Medicine', 'date': 'Feb 15, 2023', 'snippet': 'Respiratory syncytial virus (RSV) is an important cause of acute \nrespiratory infection, lower respiratory tract disease, clinical...', 'thumbnail': 'https://serpapi.com/searches/6721b18f81bab782f00122a2/images/da5561971d7a5b0ad2832799b633c8c394f3868c8cb3544baddae8da8ee89463.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5248604416847229}","{'position': 2, 'link': 'https://www.drugtopics.com/view/breaking-fda-approves-first-ever-rsv-vaccine', 'title': 'Breaking: FDA Approves First-Ever RSV Vaccine', 'source': 'Drug Topics', 'date': 'May 3, 2023', 'snippet': 'The vaccine is approved for use in adults aged 60 and older to prevent \nlower respiratory tract disease caused by RSV.', 'thumbnail': 'https://serpapi.com/searches/6721b18f81bab782f00122a2/images/da5561971d7a5b0a0b914a0f9b3a1525c5b32e36afc0d6eefc9ba8b3be5ea3ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6009575724601746}","{'position': 3, 'link': 'https://www.drugtopics.com/view/gsk-s-rsv-vaccine-now-available-in-us-pharmacies-what-you-need-to-know', 'title': 'GSK’s RSV Vaccine Now Available in Some US Pharmacies: What You Need to Know', 'source': 'Drug Topics', 'date': 'Aug 1, 2023', 'snippet': ""The FDA approved GSK's Arexvy on May 3, 2023, making it the first vaccine \nto prevent lower respiratory tract disease caused by RSV in adults aged 60 \nand older."", 'thumbnail': 'https://serpapi.com/searches/6721b18f81bab782f00122a2/images/da5561971d7a5b0a081abe794899ac6a260951750a332921a7f75f174ee72c93.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7245526313781738}","{'position': 4, 'link': 'https://www.drugtopics.com/view/the-value-of-good-neighbor-pharmacy-today-and-tomorrow', 'title': 'The Value of Good Neighbor Pharmacy Today and Tomorrow', 'source': 'Drug Topics', 'date': 'Oct 7, 2020', 'snippet': ""Brian Nightengale, President of GNP, discusses the value of Good Neighbor \nPharmacy's services and solutions in supporting independent..."", 'thumbnail': 'https://serpapi.com/searches/6721b18f81bab782f00122a2/images/da5561971d7a5b0a66f27d0c002a1a71566688c4fd725b94a17f14b6f84bf2ae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5204561948776245}",,,,,,,"['negative', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04199728,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/cob.12676', 'title': 'Glucagon‐like‐peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association - Nguyen - 2024 - Clinical Obesity', 'source': 'Wiley Online Library', 'date': 'May 23, 2024', 'snippet': 'Glucagon-like-peptide 1 receptor agonists (GLP-1RA) have transformed type 2 \ndiabetes (T2D) and obesity management.', 'thumbnail': 'https://serpapi.com/searches/6721b1a47ec4aefa940d1389/images/0c8415dd3b72c692dd48468fdbad020019de4d91a99feafe984a9d5345a9110c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5590799450874329}",,,,,,,,,,['neutral'],neutral,1 NCT00956098,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-022-01119-3', 'title': 'Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)', 'source': 'Nature', 'date': 'Aug 13, 2022', 'snippet': 'In this review, we discussed recent developments in etiology and \nprospective therapeutic targets, as well as pharmacological candidates in \npre/clinical trials...', 'thumbnail': 'https://serpapi.com/searches/6721b1c974f0a452bffe6e81/images/3154712ef40168bb6efa1fcc22d64ab459879cda7d5098e53daac72d68f2bbfe.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9206169247627258}",,,,,,,,,,['neutral'],neutral,1 NCT03844074,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/fda-rejects-intravitreal-formulation-of-bevacizumab-for-wet-amd/', 'title': 'FDA Rejects Intravitreal Formulation of Bevacizumab for Wet AMD', 'source': 'Medical Professionals Reference', 'date': 'Aug 30, 2023', 'snippet': 'The Food and Drug Administration (FDA) has issued a Complete Response \nLetter (CRL) to Outlook Therapeutics regarding the Biologics License \nApplication (BLA)...', 'thumbnail': 'https://serpapi.com/searches/6721b1d0a775f24217d434bd/images/6e68d6abe075243934487d0a371f8a724febdb7d390038f8c3e40aeff361f794.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8640140891075134}",,,,,,,,,,['neutral'],neutral,1 NCT02122913,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1714448', 'title': 'Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children', 'source': 'The New England Journal of Medicine', 'date': 'Feb 21, 2018', 'snippet': 'Fusions involving one of three tropomyosin receptor kinases (TRK) occur in \ndiverse cancers in children and adults. We evaluated the efficacy...', 'thumbnail': 'https://serpapi.com/searches/6721b1e4a54d7ea585de8c48/images/f1a57890d38a78707244ec48d33168d2df3aa8e096563ddf321a43972c0ca760.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.788867712020874}","{'position': 2, 'link': 'https://www.onclive.com/view/dr-subbiah-on-outcomes-with-larotrectinib-in-trk-fusion-positive-solid-tumors', 'title': 'Dr Subbiah on Outcomes With Larotrectinib in TRK Fusion–Positive Solid Tumors', 'source': 'OncLive', 'date': 'Aug 20, 2024', 'snippet': 'Vivek Subbiah, MD, chief, Early-Phase Drug Development, Sarah Cannon \nResearch Institute, discusses key data from the observational VICTORIA...', 'thumbnail': 'https://serpapi.com/searches/6721b1e4a54d7ea585de8c48/images/f1a57890d38a7870bf8955ba0831824928982f3bed9d2241e748c1287b7efc17.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8828447461128235}","{'position': 3, 'link': 'https://www.mdanderson.org/publications/cancer-frontline/targeted-therapy-larotrectinib-shows-marked-responses-in-patient.h00-159381156.html', 'title': 'Larotrectinib shows marked responses with NTRK gene fusions, limited response in non-fusion mutations', 'source': 'MD Anderson Cancer Center', 'date': 'Apr 28, 2020', 'snippet': 'An MD Anderson analysis of three clinical trials shows that the targeted \ntherapy drug larotrectinib resulted in a 79% overall response rate...', 'thumbnail': 'https://serpapi.com/searches/6721b1e4a54d7ea585de8c48/images/f1a57890d38a7870304093ba9d747a9cbb6c924b814053217a14dda21fdad3ee.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8391838669776917}","{'position': 4, 'link': 'https://www.clinicaltrialsarena.com/projects/vitrakvi-larotrectinib-advanced-solid-tumours/', 'title': 'Vitrakvi (larotrectinib) for Advanced Solid Tumours with NTRK Gene Fusion', 'source': 'Clinical Trials Arena', 'date': 'Dec 11, 2018', 'snippet': 'Vitrakvi (larotrectinib) is an oral tyrosine kinase inhibitor for the \ntreatment of advanced solid tumours with NTRK gene fusion.', 'thumbnail': 'https://serpapi.com/searches/6721b1e4a54d7ea585de8c48/images/f1a57890d38a78707577633240854d4eca261f2f8dd4e05781a04241d190e5e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9096885919570923}","{'position': 5, 'link': 'https://www.cancerhealth.com/blog/fda-approves-companion-diagnostic-test-vitrakvi', 'title': 'FDA Approves Companion Diagnostic Test for Vitrakvi', 'source': 'Cancer Health', 'date': 'Oct 26, 2020', 'snippet': 'On October 23, 2020, the Food and Drug Administration approved the \nnext-generation sequencing (NGS)-based FoundationOne CDx test (Foundation...', 'thumbnail': 'https://serpapi.com/searches/6721b1e4a54d7ea585de8c48/images/f1a57890d38a787043e2d7b280f190ee9b294ea4bad83c263793d71cb47bb1f0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7966646552085876}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01462942,"{'position': 1, 'link': 'https://copdnewstoday.com/news/duaklir-available-copd-patients-us/', 'title': 'Duaklir Now Available to COPD Patients in the U.S.', 'source': 'COPD News Today', 'date': 'Oct 29, 2019', 'snippet': 'Duaklir is now available to patients with chronic obstructive pulmonary \ndisease (COPD) living in the U.S., Circassia Pharmaceuticals...', 'thumbnail': 'https://serpapi.com/searches/6721b1ee8a7c0939084c5c6a/images/03728386d5e4cd12d0739064ee53ec519e57aa668daf7290d19280e62044a556.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7435298562049866}",,,,,,,,,,['neutral'],neutral,1 NCT00120003,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/strokeaha.113.001022', 'title': 'Effects of Candesartan in Acute Stroke on Cognitive Function and Quality of Life:', 'source': 'American Heart Association Journals', 'date': 'May 9, 2013', 'snippet': 'Background and Purpose—High blood pressure is common in the acute phase of \nstroke and is associated with poor outcome.', 'thumbnail': 'https://serpapi.com/searches/6721b1ef8f2bc259e15fa5b3/images/e842102b296d5d013119a0f08766e4fe3d6a69bd51a57374350f48e8a0c3c20a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6420814990997314}",,,,,,,,,,['negative'],negative,0 NCT03602560,"{'position': 1, 'link': 'https://liverdiseasenews.com/news/liver-damage-itch-from-primary-biliary-cholangitis-eased-with-seladelpar/', 'title': 'Seladelpar eases liver damage, itch in primary biliary cholangitis', 'source': 'liverdiseasenews.com', 'date': 'May 22, 2024', 'snippet': ""One year of treatment with Gilead Sciences' seladelpar normalized \nbiomarkers of liver injury and rapidly reduced itch for most people with \nprimary biliary..."", 'thumbnail': 'https://serpapi.com/searches/6721b2182c566df1ca1ef4ba/images/d4e54e170c7ed3ab1ed796f1c379d50f74abc102d033cc670d0e1256644799a9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7402761578559875}","{'position': 2, 'link': 'https://liverdiseasenews.com/news/seladelpar-lowers-levels-il-31-driving-pruritus-pbc-trial/', 'title': 'Seladelpar lowers levels of molecule driving itch with PBC: Phase 3 trial', 'source': 'Liver Disease News', 'date': 'Feb 7, 2024', 'snippet': 'An analysis of Phase 3 trial data found a 52% drop in blood levels of \nIL-31, known to promote itch, in PBC patients treated at high dose.', 'thumbnail': 'https://serpapi.com/searches/6721b2182c566df1ca1ef4ba/images/d4e54e170c7ed3ab74d41e9926347f0381a004d92538d777b9ef5996ff2fd6ab.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7899602055549622}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02624947,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1329426/full', 'title': 'Clinical research on RSV prevention in children and pregnant women: progress and perspectives', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': 'This review provides a comprehensive summary of RSV monoclonal antibody \n(mAb) and vaccine clinical trials registered on ClinicalTrials.gov', 'thumbnail': 'https://serpapi.com/searches/6721b227c024d17e3ab52f67/images/bc4e9b76ee2a7fa7a6ca84854bfd1987b388078abb4807fbc337f9263f0e1617.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8756221532821655}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1908380', 'title': 'Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants', 'source': 'The New England Journal of Medicine', 'date': 'Jul 29, 2020', 'snippet': 'We describe the results of a phase 3 trial evaluating the safety and \nimmunogenicity of RSV F vaccine in pregnant women and vaccine efficacy.', 'thumbnail': 'https://serpapi.com/searches/6721b227c024d17e3ab52f67/images/bc4e9b76ee2a7fa78480896b99bc46dc17ef2c4c7abec4f3742832ff3fad516b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9224299192428589}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03852433,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2213429', 'title': 'A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D', 'source': 'The New England Journal of Medicine', 'date': 'Jun 22, 2023', 'snippet': 'Coinfection with hepatitis D virus (HDV) accelerates the progression of \nliver disease associated with chronic hepatitis B. Bulevirtide inhibits the \nentry of...', 'thumbnail': 'https://serpapi.com/searches/6721b239ba1142b4b1190fcd/images/27389f6b00bc99bd4975146822d5887511a1325be02e4b01fc3b757c85400e3b.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6427436470985413}",,,,,,,,,,['negative'],negative,0 NCT00049829,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa067312', 'title': 'Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis', 'source': 'The New England Journal of Medicine', 'date': 'May 3, 2007', 'snippet': 'A single infusion of intravenous zoledronic acid decreases bone turnover \nand improves bone density at 12 months in postmenopausal women with \nosteoporosis.', 'thumbnail': 'https://serpapi.com/searches/6721b23f4677bf469c242595/images/ea481e20c7b44039c4bb0095c20cd08e873cac561c184cb7d7274be585a40684.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7942545413970947}",,,,,,,,,,['neutral'],neutral,1 NCT02457845,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2024947', 'title': 'Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas', 'source': 'The New England Journal of Medicine', 'date': 'Apr 10, 2021', 'snippet': 'Pediatric brain tumors are highly sensitive to oncolytic virotherapy with \ngenetically engineered herpes simplex virus type 1 (HSV-1) G207.', 'thumbnail': 'https://serpapi.com/searches/6721b24624296a3c4a748beb/images/5c78eb14742d04292ab18b3e000555090dfe082ad1f451fbfb7f1d8a90130d35.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7477931380271912}",,,,,,,,,,['neutral'],neutral,1 NCT03412565,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-023-00805-x', 'title': 'Daratumumab, carfilzomib, and dexamethasone in relapsed or refractory myeloma: final analysis of PLEIADES and EQUULEUS | Blood Cancer Journal', 'source': 'Nature', 'date': 'Mar 7, 2023', 'snippet': 'We report final data from PLEIADES and EQUULEUS, with a median follow-up of \n12.4 and 23.7 months, respectively.', 'thumbnail': 'https://serpapi.com/searches/6721b25e52a04e7b0718215d/images/3426ef1ab2ffc9e7553b57c0d6049518d683e7fc70fd0c8fe4ef6c36fd9d7369.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9076092839241028}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/fda-approves-darzalex-faspro-injection-therapy-for-multiple-myeloma/', 'title': 'FDA Approves Darzalex Faspro as Injection Therapy for Multiple Myeloma', 'source': 'Myeloma Research News', 'date': 'May 5, 2020', 'snippet': ""The U.S. Food and Drug Administration (FDA) approved Janssen's new \nformulation of daratumumab — a subcutaneous or under-the-skin injection..."", 'thumbnail': 'https://serpapi.com/searches/6721b25e52a04e7b0718215d/images/3426ef1ab2ffc9e7fd5d0f68829859a29bbe443f3a2a84b0db55a7118290daf0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6539252400398254}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05567952,"{'position': 1, 'link': 'https://www.cdc.gov/mmwr/volumes/72/wr/mm7251a1.htm', 'title': 'SARS-CoV-2 Rebound With and Without Use of COVID-19 Oral Antivirals | MMWR', 'source': 'Centers for Disease Control and Prevention (.gov)', 'date': 'Dec 22, 2023', 'snippet': 'CDC reviewed COVID-19 rebound studies among patients who did and did not \nreceive antiviral treatment.', 'thumbnail': 'https://serpapi.com/searches/6721b2789062f826e6c06d4f/images/dde4226fc7f22fe472844a62eba792f208227c41ca5be7c95278aad19354ee12.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8883197903633118}",,,,,,,,,,['neutral'],neutral,1 NCT04778410,"{'position': 1, 'link': 'https://www.onclive.com/view/gilead-discontinues-phase-3-enhance-2-trial-of-magrolimab-plus-azacitidine-in-tp53-mutant-aml', 'title': 'Gilead Discontinues Phase 3 ENHANCE-2 Trial of Magrolimab Plus Azacitidine in TP53-Mutant AML', 'source': 'OncLive', 'date': 'Sep 27, 2023', 'snippet': ""The phase 3 ENHANCE-2 trial examining the frontline combination of \nmagrolimab and azacitidine vs physician's choice of venetoclax with..."", 'thumbnail': 'https://serpapi.com/searches/6721b27b7ef9fa1a056ca893/images/d6e057c5464ce1e2ecb677c9346382bf2ededee9e3ad5c4e7840f8c90b064053.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9308812022209167}",,,,,,,,,,['neutral'],neutral,1 NCT00782067,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1513098', 'title': 'Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis', 'source': 'The New England Journal of Medicine', 'date': 'Jun 30, 2016', 'snippet': 'In this open-label study, midostaurin showed efficacy in patients with \nadvanced systemic mastocytosis, including the highly fatal variant \nmast-cell leukemia.', 'thumbnail': 'https://serpapi.com/searches/6721b28589055e8ea6cb7bce/images/2644e564c08d8b22ec8288f66362de496b328a8816b4ae689e8af47adae6408f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7889068126678467}",,,,,,,,,,['neutral'],neutral,1 NCT00810693,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1209655', 'title': 'Riociguat for the Treatment of Pulmonary Arterial Hypertension', 'source': 'The New England Journal of Medicine', 'date': 'Jul 25, 2013', 'snippet': 'Riociguat, a soluble guanylate cyclase stimulator, has been shown in a \nphase 2 trial to be beneficial in the treatment of pulmonary arterial \nhypertension.', 'thumbnail': 'https://serpapi.com/searches/6721b2aa2da1575f5eaf02f2/images/89db599ddcdad6081b8aa0a9c02b8e0f2a48a92f2f75c070c7de837660151316.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6600370407104492}","{'position': 2, 'link': 'https://sclerodermanews.com/2016/07/29/Adempas-Equally-Beneficial-in-Scleroderma-and-Other-Connective-Tissue-Disease-PAH-patients/', 'title': 'PAH Scleroderma Patients, Others with PAH-CTD Benefit from Adempas', 'source': 'Scleroderma News', 'date': 'Aug 2, 2016', 'snippet': 'Scleroderma patients with pulmonary arterial hypertension (PAH) benefit \nequally well from treatment with Adempas (riociguat) as PAH patients...', 'thumbnail': 'https://serpapi.com/searches/6721b2aa2da1575f5eaf02f2/images/89db599ddcdad6081401e5480016d669b4e23d520b41343cdee2247d507fd59a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7391170859336853}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04927975,"{'position': 1, 'link': 'https://www.medicalnewstoday.com/articles/jak-inhibitors-for-vitiligo', 'title': 'What to know about JAK inhibitor treatments for vitiligo', 'source': 'MedicalNewsToday', 'date': 'Nov 17, 2022', 'snippet': 'Ruxolitinib cream is the first FDA-approved JAK inhibitor for skin \nrepigmentation in people with vitiligo, paving the way for additional oral \nand topical JAK...', 'thumbnail': 'https://serpapi.com/searches/6721b2b50c6668b7c76dbc5c/images/972b6e8ca06d5e785c1ae01eab6212e3ae4f60850a97633013ebbe48e332bf44.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7310158014297485}","{'position': 2, 'link': 'https://www.thepharmaletter.com/biotechnology/phase-ii-rinvoq-trial-hits-main-goal-in-vitiligo', 'title': 'Phase II Rinvoq trial hits main goal in vitiligo', 'source': 'The Pharma Letter', 'date': 'Oct 12, 2023', 'snippet': 'At the European Academy of Dermatology and Venerology (EADV) congress in \nBerlin, AbbVie is presenting positive results from the Phase IIb...', 'thumbnail': 'https://serpapi.com/searches/6721b2b50c6668b7c76dbc5c/images/972b6e8ca06d5e78d5a103c0101db94a45873cf4128feb2f8a3672f6d3cdd375.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5259546637535095}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04204408,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/mim8-better-standard-hemophilia-a-treatments-phase-3-trial/', 'title': 'Mim8 seen as better than standard hem A therapies at bleed control', 'source': 'Hemophilia News Today', 'date': 'May 22, 2024', 'snippet': 'Weekly and monthly treatment with Mim8, an investigational antibody \ntherapy, was seen to be better than on-demand or standard preventive \ntreatments at reducing...', 'thumbnail': 'https://serpapi.com/searches/6721b2b6cb33d011be8457f3/images/0fa4f1ba75b44171d1c504e159101cb1fdf6135335d0ef5afe82471835712811.png', 'sentiment': 'positive', 'sentiment_prob': 0.6799125075340271}",,,,,,,,,,['positive'],positive,1 NCT05252338,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S2405844024030020', 'title': 'The clinical impact of mRNA therapeutics in the treatment of cancers, infections, genetic disorders, and autoimmune diseases', 'source': 'ScienceDirect.com', 'date': 'Mar 15, 2024', 'snippet': 'This review aims to elucidate the advancements in the clinical applications \nof mRNAs for addressing significant health-related challenges such as \ncancer,...', 'thumbnail': 'https://serpapi.com/searches/6721b2c0a5aae9207bffd5d9/images/c01c1600c97f3cf8907bfd5e1721f30bbc02ef932a2c9d1acc9d52a5f20b1672.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Food and Drug Administration approved an unique formulation of \nsodium thiosulfate (Pedmark) for the prevention of platinum-induced...', 'thumbnail': 'https://serpapi.com/searches/6721b2d818787d3f6f66c9ea/images/2e7d2d5fc3aaa2bc5ca3d66c5df15e315ce21744e7834c9f3cd5b2d9b9dea875.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7437710762023926}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05163847,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/flugens-intranasal-flu-vaccine-boosts-flu-shot-efficacy/', 'title': 'FluGen’s intranasal flu vaccine boosts flu shot efficacy', 'source': 'Clinical Trials Arena', 'date': 'Jul 15, 2024', 'snippet': ""A study shows that the co-administration of FluGen's intranasal M2SR and a \nhigh-dose flu shot improves the overall efficacy of flu vaccines in the \nelderly..."", 'thumbnail': 'https://serpapi.com/searches/6721b2e3310300643ce5fbcb/images/5efb290a69d19b8606614c57e1aefde549619dbd587cceceaa43695199e38951.jpeg', 'sentiment': 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discuss recent reports connecting KRAS mutations with tumour-promoting \ninflammation and immune modulation caused by KRAS that leads to immune \nescape in the...', 'thumbnail': 'https://serpapi.com/searches/6721b2f5fda26de16dd7459d/images/58673e5179b4e93764a95e4644d8dc1eba00b57b5cd9739d391ceae7a7394232.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6028968095779419}",,,,,,,,,,['neutral'],neutral,1 NCT00315757,"{'position': 1, 'link': 'https://www.nature.com/articles/s41418-022-01059-z', 'title': 'Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries', 'source': 'Nature', 'date': 'Oct 4, 2022', 'snippet': 'Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) can \ninduce apoptosis in a wide variety of cancer cells, both in vitro...', 'thumbnail': 'https://serpapi.com/searches/6721b312caddc31ce57667ba/images/4e9b85b643bc3e8d48b341668a3e27a81fa15ed8cf5ded2b649f214e50ce2303.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Adoptive cell therapy (ACT) with autologous tumor-infiltrating lymphocytes \n(TILs) can induce durable complete tumor regression in patients...', 'thumbnail': 'https://serpapi.com/searches/6721b32cee677f6d30533aca/images/1eaeb3d95b78e53391ed6ee37c171c74bd0fe7c25b80ef22ac85240138bf769d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.66169273853302}",,,,,,,,,,['neutral'],neutral,1 NCT02869035,"{'position': 1, 'link': 'https://www.nature.com/articles/s41398-022-02240-1', 'title': 'Evaluating cognitive disturbances as treatment target and predictor of antidepressant action in major depressive disorder: A NeuroPharm study', 'source': 'Nature', 'date': 'Nov 8, 2022', 'snippet': 'Cognitive disturbances in major depressive disorder (MDD) constitute a \ncritical treatment target and hold promise as an early predictor of \nantidepressant...', 'thumbnail': 'https://serpapi.com/searches/6721b338a5d70237c4700b58/images/2b89c61abac6e1782e83126cb5aa846594f928304308ef377a049a5cf4aa58e2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8646960258483887}",,,,,,,,,,['neutral'],neutral,1 NCT00430365,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1114138', 'title': 'Lenalidomide Maintenance after Stem-Cell Transplantation for Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'May 10, 2012', 'snippet': 'High-dose chemotherapy with autologous stem-cell transplantation is a \nstandard treatment for young patients with multiple myeloma.', 'thumbnail': 'https://serpapi.com/searches/6721b3464e9efc40cad56193/images/fdcfec6898eb397201c04ee38fe8d9c823a06f66f6087aac2f2eb881b3b771d9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8278542160987854}",,,,,,,,,,['neutral'],neutral,1 NCT05512949,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/clinical-trial-evaluating-monkeypox-vaccine-begins', 'title': 'Clinical Trial Evaluating Monkeypox Vaccine Begins', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Sep 8, 2022', 'snippet': 'Interested volunteers can visit clinicaltrials.gov and search identifier \nNCT05512949 for more information about the trial, including a list...', 'thumbnail': 'https://serpapi.com/searches/6721b34817b10e7c7bb60bb2/images/527e4e17ccbaf6f13a52c639e5c1d53e825235dab89a9457117698cd20a8345d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9237444400787354}","{'position': 2, 'link': 'https://www.europeanpharmaceuticalreview.com/news/174314/us-begins-monkeypox-vaccine-and-therapeutic-trials/', 'title': 'US begins monkeypox vaccine and therapeutic trials', 'source': 'European Pharmaceutical Review', 'date': 'Sep 12, 2022', 'snippet': 'US National Institutes of Health initiates trials to evaluate antiviral \ntecovirimat (TPOXX) and possibility of delivering Jynneos vaccine \nintradermally.', 'thumbnail': 'https://serpapi.com/searches/6721b34817b10e7c7bb60bb2/images/527e4e17ccbaf6f15e4ac777cd2ca8eb77ce24fdc079a74a26943b869c3a9144.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9237051606178284}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02819518,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2202809', 'title': 'Pembrolizumab plus Chemotherapy in Advanced Triple-Negative Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jul 20, 2022', 'snippet': 'In an interim analysis of this phase 3 trial, the addition of pembrolizumab \nto chemotherapy resulted in longer progression-free survival...', 'thumbnail': 'https://serpapi.com/searches/6721b350544c49a3ab20630f/images/7c2b43ae9e70674e6bc3e68b4f977013eb0f923dea7f47da282ea12af6cea6cf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7620288729667664}","{'position': 2, 'link': 'https://www.nature.com/articles/s41523-024-00679-7', 'title': 'Results from the randomized KEYNOTE-355 study of pembrolizumab plus chemotherapy for Asian patients with advanced TNBC | npj Breast Cancer', 'source': 'Nature', 'date': '1 month ago', 'snippet': 'In the phase 3 KEYNOTE-355 study (NCT02819518), pembrolizumab plus \nchemotherapy demonstrated statistically significant and clinically...', 'thumbnail': 'https://serpapi.com/searches/6721b350544c49a3ab20630f/images/7c2b43ae9e70674ec8674ba109ac3a46808f42ae534c850acde91faac9137e86.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9065072536468506}","{'position': 3, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.5757', 'title': 'Pembrolizumab plus chemotherapy in Japanese patients with triple-negative breast cancer: Results from KEYNOTE-355', 'source': 'Wiley Online Library', 'date': 'Mar 14, 2023', 'snippet': 'Overall survival was prolonged with pembrolizumab plus chemotherapy \ncompared with placebo plus chemotherapy among patients with previously...', 'thumbnail': 'https://serpapi.com/searches/6721b350544c49a3ab20630f/images/7c2b43ae9e70674e2872989b79f972ffc2c5fd0d16180130009ba3f8ecc45964.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8783368468284607}","{'position': 4, 'link': 'https://breastcancer-news.com/2020/11/19/fda-approves-keytruda-chemo-combo-for-advanced-tnbc-positive-for-pd-l1/', 'title': 'FDA Approves Keytruda-chemo Combo for Advanced TNBC Positive for PD-L1', 'source': 'Breast Cancer News', 'date': 'Nov 19, 2020', 'snippet': 'The US Food and Drug Administration (FDA) has approved Keytruda \n(pembrolizumab), in combination with chemotherapy, to treat people with \nadvanced triple-...', 'thumbnail': 'https://serpapi.com/searches/6721b350544c49a3ab20630f/images/7c2b43ae9e70674e0d8f088d284881f440ab60585f2654f3ce966e5f740fdfbe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7811800837516785}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT05142722,"{'position': 1, 'link': 'https://www.healio.com/news/cardiology/20221219/pipeline-pulse-a-look-at-tirzepatide-ziltivekimab-and-obicetrapib', 'title': 'Pipeline Pulse: A look at tirzepatide, ziltivekimab and obicetrapib', 'source': 'Healio', 'date': 'Dec 19, 2022', 'snippet': 'The field of cardiology has seen stunning advances in the past several \nyears: HF, dyslipidemia and cardiomyopathy are just three of the...', 'thumbnail': 'https://serpapi.com/searches/6721b36e4300ce5d04a69767/images/74d6f656dad908cf746bafc855a3be8efb28e3e9a8079da73930059d4cea9eb2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8222142457962036}",,,,,,,,,,['positive'],positive,1 NCT00906399,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2021/02/01/biogen-announces-fda-approval-of-plegridy-peginterferon-beta-1a-intramuscular-administration-for-multiple-sclerosis/', 'title': 'FDA Approves Plegridy as Intramuscular Injection for Relapsing MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Feb 2, 2021', 'snippet': 'The US Food and Drug Administration (FDA) has approved an intramuscular \ninjection formulation of Plegridy (peginterferon beta-1a) to treat people \nwith...', 'thumbnail': 'https://serpapi.com/searches/6721b389e30abcd38625fce7/images/369e6dd917186238c0d5c95d5336edee39c35339f1a2516b40f8e8ed51a48278.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8156218528747559}",,,,,,,,,,['neutral'],neutral,1 NCT02782858,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/gnbac1-for-rrms/', 'title': 'Temelimab in MS | Experimental MS Treatments', 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 9, 2022', 'snippet': 'Temelimab is a therapy being evaluated as a potential treatment for MS. \nLearn more about its uses, side effects, and clinical testing.', 'thumbnail': 'https://serpapi.com/searches/6721b3c97ac73169c870ec98/images/674c92c70cbf23ae791467487fd94c4eb14924ac9917403480ce18efadc0ee0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9337586760520935}",,,,,,,,,,['neutral'],neutral,1 NCT02213263,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/ruxience-biosimilar-rituxan-approved-by-fda-2-anca-vasculitis-subtypes/', 'title': 'FDA Approves Rituxan Biosimilar Ruxience for 2 ANCA Vasculitis Subtypes', 'source': 'ANCA Vasculitis News', 'date': 'Jul 30, 2019', 'snippet': ""The U.S. Food and Drug Administration (FDA) has approved Pfizer's Ruxience \n(rituximab-pvvr), a biosimilar to Rituxan (rituximab),..."", 'thumbnail': 'https://serpapi.com/searches/6721b3d6d11a89f6dc4dfad3/images/16fe07daac8c0bb9e605b0a94597f8f920b2ff7781929c861e419aaafeff552f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7757377624511719}",,,,,,,,,,['neutral'],neutral,1 NCT00390299,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-43076-7', 'title': 'Carcinoembryonic antigen-expressing oncolytic measles virus derivative in recurrent glioblastoma: a phase 1 trial', 'source': 'Nature', 'date': 'Jan 12, 2024', 'snippet': 'Measles virus (MV) vaccine strains have shown significant preclinical \nantitumor activity against glioblastoma (GBM), the most lethal glioma...', 'thumbnail': 'https://serpapi.com/searches/6721b3db9e38e52c96d86bb1/images/3c43ac7db1b41ff924bfb9868d526c53211707cde52284a316acb1198f887980.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7172777652740479}",,,,,,,,,,['neutral'],neutral,1 NCT02494479,"{'position': 1, 'link': 'https://psoriasisnewstoday.com/2017/05/11/cellceutix-has-70-percent-of-patients-it-wants-for-trial-of-psoriasis-therapy-prurisol/', 'title': 'Phase 2b Trial of Psoriasis Therapy Prurisol Reaches 70% of Participant Target', 'source': 'Psoriasis News Today', 'date': 'May 11, 2017', 'snippet': 'An already started Phase 2b clinical trial of Prurisol as a treatment for \nmoderate-to-severe chronic plaque psoriasis has recruited more than 70 \npercent of the...', 'thumbnail': 'https://serpapi.com/searches/6721b3e5f9f9048808756710/images/cbefdfe81edacc891254279e7f8881443228b46819aacec089db2502a7b7e913.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7885826826095581}",,,,,,,,,,['neutral'],neutral,1 NCT03399370,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1912387', 'title': 'Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol', 'source': 'The New England Journal of Medicine', 'date': 'Mar 18, 2020', 'snippet': 'Previous studies suggest that inclisiran might provide sustained reductions \nin low-density lipoprotein (LDL) cholesterol levels with infrequent dosing.', 'thumbnail': 'https://serpapi.com/searches/6721b3e71397bae53c6bb816/images/c1949dd0ab2c3d4242d47819c8d01e693f98a646b7f0a6af5fd458222f86c48c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8475676774978638}",,,,,,,,,,['neutral'],neutral,1 NCT05074472,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/monoclonal-antibody-granted-orphan-drug-status-for-pancreatic-cancer/', 'title': 'Monoclonal Antibody Granted Orphan Drug Status for Pancreatic Cancer', 'source': 'Medical Professionals Reference', 'date': 'Dec 27, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted Orphan Drug designation \nto ZB131 for the treatment of pancreatic cancer.', 'thumbnail': 'https://serpapi.com/searches/6721b3ef7ef9fa1a056ca982/images/bdab6e58bafa2139935f2a35bba51a8851b168172f71d1dc08cb2d9b777c7be8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9232718348503113}",,,,,,,,,,['neutral'],neutral,1 NCT01180322,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-019-0395-y', 'title': 'Randomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine', 'source': 'Nature', 'date': 'Feb 6, 2019', 'snippet': 'The aim of this randomized phase-II study was to evaluate the effect of \nsubstituting cytarabine by azacitidine in intensive induction...', 'thumbnail': 'https://serpapi.com/searches/6721b40d717bffe934197350/images/50a861259f60e73c74634d2c13f8a8e935d30d51462bbf1222932c6681f7db45.png', 'sentiment': 'neutral', 'sentiment_prob': 0.890680193901062}",,,,,,,,,,['neutral'],neutral,1 NCT04362085,"{'position': 1, 'link': 'https://www.bmj.com/content/375/bmj.n2400', 'title': 'Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial', 'source': 'The BMJ', 'date': 'Oct 14, 2021', 'snippet': 'Therapeutic heparin was not significantly associated with a reduction in \nthe primary outcome but the odds of death at 28 days was decreased.', 'thumbnail': 'https://serpapi.com/searches/6721b41cb6a79cce33177d6b/images/591e37c15d8548d37ad7b9950a5f2b21bf154a68f13d313aa1b1e6f9b98deaa8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7524961233139038}",,,,,,,,,,['neutral'],neutral,1 NCT01634139,"{'position': 1, 'link': 'https://lungdiseasenews.com/2017/02/20/asthmatic-children-ages-6-and-older-can-now-use-spiriva-respimat-for-maintenance-therapy/', 'title': 'Asthmatic Kids 6 and Up Can Use Spiriva Respimat as Maintenance Therapy', 'source': 'Lung Disease News', 'date': 'Feb 20, 2017', 'snippet': 'The US Food and Drug Administration (FDA) expanded the approval of \nsteroid-free Spiriva Respimat (tiotropium bromide) for the maintenance \ntreatment of asthma...', 'thumbnail': 'https://serpapi.com/searches/6721b42f9109867ea006e66b/images/a8f188a8c36d3c408cb69a6e3eeed221e5f857cba90218e818041c4f5989e5e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7848676443099976}",,,,,,,,,,['neutral'],neutral,1 NCT00923312,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.887125/full', 'title': 'mRNA Vaccines: The Dawn of a New Era of Cancer Immunotherapy', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': 'mRNA therapy is a novel anticancer strategy based on in vitro transcription \n(IVT), which has potential for the treatment of malignant tumors.', 'thumbnail': 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to Slow SOD1-ALS Progression |...', 'source': 'ALS News Today', 'date': 'Sep 23, 2022', 'snippet': 'Early treatment with tofersen was found to slow disease progression in \npeople with SOD1-ALS in the VALOR trial and its open-label extension.', 'thumbnail': 'https://serpapi.com/searches/6721b48c52a04e7ad6d80397/images/c1e33b85e5add2bc1d7491e70d57e6205615d81ef8138f5a86cebef7f226e733.png', 'sentiment': 'neutral', 'sentiment_prob': 0.49916312098503113}","{'position': 5, 'link': 'https://alsnewstoday.com/news/als-disease-progression-slowed-real-world-setting-with-qalsody/', 'title': 'Qalsody slows ALS disease progression in real-world settings', 'source': 'ALS News Today', 'date': 'Apr 25, 2024', 'snippet': ""Qalsody also stabilized patients' quality of life and lowered nerve \ndamage-related biomarkers, consistent with data supporting its approval."", 'thumbnail': 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Dupilumab, a fully human...', 'thumbnail': 'https://serpapi.com/searches/6721b809e50bc0cdb2059332/images/28bb2aec212c5a1dcff065e6cf109834ff80b56df32d2fc4db658ab842983739.png', 'sentiment': 'negative', 'sentiment_prob': 0.5187826752662659}",,,,,,,,,,['negative'],negative,0 NCT03687255,"{'position': 1, 'link': 'https://www.urologytimes.com/view/fda-approves-cefepime-enmetazobactam-for-complicated-uti', 'title': 'FDA approves cefepime/enmetazobactam for complicated UTI', 'source': 'Urology Times', 'date': 'Feb 27, 2024', 'snippet': 'The FDA approval is supported by data from the phase 3 ALLIUM trial, which \ndemonstrated the non-inferiority and superiority of...', 'thumbnail': 'https://serpapi.com/searches/6721b825237938d086ab4abe/images/e2e4dcd6aef5a9662904e60c9751518549a3de1749998050d145cdc831124f96.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5308451652526855}",,,,,,,,,,['neutral'],neutral,1 NCT04872101,"{'position': 1, 'link': 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2024 (GLOBE NEWSWIRE) -- Abeona Therapeutics Inc. \n(Nasdaq: ABEO) today announced that the Company has resubmitted its...', 'thumbnail': 'https://serpapi.com/searches/6721ba5d14c31e91b1a9ca2a/images/d82f897079e6b046a02df14ed22f9bce93841f5c4fd6a26434c7daf663c3a67b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8937640190124512}","{'position': 2, 'link': 'https://epidermolysisbullosanews.com/news/pivotal-eb-101-cell-therapy-trial-rdeb-adds-2nd-site-other-us-coast/', 'title': 'Pivotal EB-101 Cell Therapy Trial Adds 2nd Site on Other US Coast', 'source': 'Epidermolysis Bullosa News', 'date': 'Jul 30, 2021', 'snippet': 'The VIITAL study, testing EB-101 for RDEB at Stanford in California, now \nhas added a second site at UMass Memorial Medical Center.', 'thumbnail': 'https://serpapi.com/searches/6721ba5d14c31e91b1a9ca2a/images/d82f897079e6b04667481d61b63c98d3887a82cde8b81bc70d94e9556132eaf5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9427775144577026}",,,,,,,,,"['neutral', 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disappoint with major advancements in acute ischemic \nstroke (AIS) and intracranial hemorrhage (ICH) care across...', 'thumbnail': 'https://serpapi.com/searches/6721ba78a5d70237c4700fb6/images/451db7875859d0e92ed280debb8f5d8625ca77174d50c2f8ecbc190c46510a8b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.9299209713935852}",,,,,,,,,,['positive'],positive,1 NCT03934307,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2208391', 'title': 'Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension', 'source': 'The New England Journal of Medicine', 'date': 'Jul 19, 2023', 'snippet': 'Angiotensinogen is the sole precursor of angiotensin peptides and has a key \nrole in the pathogenesis of hypertension.', 'thumbnail': 'https://serpapi.com/searches/6721ba9d51d84d1f0a6ed4e3/images/61c2cfcf12021317c19b30a510f0f76c974213420f1a14797fa989d0a49486c0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8883540034294128}",,,,,,,,,,['neutral'],neutral,1 NCT02122952,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1706198', 'title': 'Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy', 'source': 'The New England Journal of Medicine', 'date': 'Nov 2, 2017', 'snippet': 'Spinal muscular atrophy type 1 (SMA1) is a progressive, monogenic motor \nneuron disease with an onset during infancy that results in failure...', 'thumbnail': 'https://serpapi.com/searches/6721baa698876dbcee669f57/images/b8bccdfd70c084a9398c13fc45deb964d4fea173206e92f506f64dbfdb24e17f.png', 'sentiment': 'negative', 'sentiment_prob': 0.7062687873840332}",,,,,,,,,,['negative'],negative,0 NCT01734928,"{'position': 1, 'link': 'https://www.oncnursingnews.com/view/pvd-confers-a-small-os-benefit-to-patients-with-relapsed-refractory-multiple-myeloma', 'title': 'PVd Confers a Small OS Benefit to Patients With Relapsed/Refractory Multiple Myeloma', 'source': 'Oncology Nursing News', 'date': 'Oct 1, 2023', 'snippet': 'Patients who received pomalidomide, bortezomib, and dexamethasone achieved \na median overall survival of 35.6 months compared with 31.6...', 'thumbnail': 'https://serpapi.com/searches/6721baa99819f38857e0d4f5/images/7874f6e51856b66e3dd716d618ab1ae4c17b9396595efc67469d8bbb9af0e04d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8126075863838196}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/optimismm-trial-shows-benefit-of-pomalyst-combo-for-resistant-mm/', 'title': 'OPTIMISMM Trial Shows Benefit of Pomalyst Combo for Resistant MM', 'source': 'Myeloma Research News', 'date': 'May 31, 2019', 'snippet': 'Pivotal OPTIMISMM trial shows that combining Pomalyst with Velcade and \ndexamethasone can prolong survival of patients with...', 'thumbnail': 'https://serpapi.com/searches/6721baa99819f38857e0d4f5/images/7874f6e51856b66e3d943af1c55ce80abc36143f29ffcc5214897f4f2d172ae6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6882515549659729}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04796896,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209367', 'title': 'Evaluation of mRNA-1273 Vaccine in Children 6 Months to 5 Years of Age', 'source': 'The New England Journal of Medicine', 'date': 'Oct 19, 2022', 'snippet': 'The safety, reactogenicity, immunogenicity, and efficacy of the mRNA-1273 \ncoronavirus disease 2019 (Covid-19) vaccine in young children are...', 'thumbnail': 'https://serpapi.com/searches/6721bac37f37191077d4c015/images/6da48aefc2480fbd78c48deca5380fd42db1689e23589ca92702ec78b09148c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8973256945610046}",,,,,,,,,,['neutral'],neutral,1 NCT01534403,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/epratuzumab', 'title': 'Epratuzumab', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Systemic Lupus Erythematosus, Pharmacokinetics Study of Epratuzumab in \nSystemic Lupus Erythematosus (SLE), Phase 2, SL0002', 'thumbnail': 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Maintenance Treatment Breztri Aerosphere Approved by FDA', 'source': 'COPD News Today', 'date': 'Jul 28, 2020', 'snippet': ""AstraZeneca's Breztri Aerosphere has been approved by the U.S. Food and \nDrug Administration as a maintenance treatment for COPD."", 'thumbnail': 'https://serpapi.com/searches/6721bb3aa88278df22a19d32/images/5c4fb1f8415af546763eaa59c192c15a9dbdd87483cd21a1caf53a2bf046807d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6785445213317871}","{'position': 3, 'link': 'https://copdnewstoday.com/news/copd-triple-combination-therapy-approved-china-astra-zeneca/', 'title': 'COPD Triple-combination Therapy Approved in China, AstraZeneca Announces', 'source': 'COPD News Today', 'date': 'Jan 3, 2020', 'snippet': ""AstraZeneca's triple-combination therapy has been approved in China for the \nmaintenance treatment of chronic obstructive pulmonary disease..."", 'thumbnail': 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'https://www.nejm.org/doi/full/10.1056/NEJMoa0910383', 'title': 'Adjuvant Trastuzumab in HER2-Positive Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 6, 2011', 'snippet': 'Trastuzumab improves survival in the adjuvant treatment of HER-positive \nbreast cancer, although combined therapy with anthracycline-based regimens \nhas been...', 'thumbnail': 'https://serpapi.com/searches/6721bb4274f0a452ea2b101b/images/b6c069d0288e17e9b8b20190b632692bcde2b0070cbb459de4cf21583b7da66f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6241481900215149}",,,,,,,,,,['neutral'],neutral,1 NCT04483947,"{'position': 1, 'link': 'https://www.nature.com/articles/s41575-023-00796-x', 'title': 'Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach', 'source': 'Nature', 'date': 'Jun 2, 2023', 'snippet': 'In this Perspective, we discuss why antifibrotic effects observed in NASH \npharmacotherapy trials have been underwhelming and outline potential \napproaches.', 'thumbnail': 'https://serpapi.com/searches/6721bb69667ec57cb39be1be/images/ea7f0e943ff50de71cb4861b4e718643d6afe34a9cf320b97b91b563814ce0bb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8069649934768677}","{'position': 2, 'link': 'https://www.nature.com/articles/s41392-022-01119-3', 'title': 'Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)', 'source': 'Nature', 'date': 'Aug 13, 2022', 'snippet': 'In this review, we discussed recent developments in etiology and \nprospective therapeutic targets, as well as pharmacological candidates in \npre/clinical trials...', 'thumbnail': 'https://serpapi.com/searches/6721bb69667ec57cb39be1be/images/ea7f0e943ff50de7b05404d2a5e77db62d7ba7b66bbf138332061eaf50576ea8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9206169247627258}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05080270,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/06/06/early-promise-treating-ms-seen-with-fibrobiologics-fibroblast-therapy/', 'title': ""Early Promise in Treating MS Seen With FibroBiologic's Fibroblast Therapy"", 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 6, 2022', 'snippet': 'A fibroblast cell therapy developed by FibroBiologics was effective in a \nmouse model of multiple sclerosis and safe in five patients.', 'thumbnail': 'https://serpapi.com/searches/6721bb9cf9f904883974eb58/images/f641d67f4a01c9a2400eca3a34f69bc2c28b8d802b85e96a2690f0023496df56.png', 'sentiment': 'positive', 'sentiment_prob': 0.6921964287757874}",,,,,,,,,,['positive'],positive,1 NCT02580552,"{'position': 1, 'link': 'https://www.nature.com/articles/s12276-023-01050-9', 'title': 'MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies', 'source': 'Nature', 'date': 'Jul 10, 2023', 'snippet': 'As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a \ncrucial role in cancer development. Since the discovery of the...', 'thumbnail': 'https://serpapi.com/searches/6721bbb26ad3c98a6ed69369/images/a3c485ba5dc6b411d1ff481b378ee6b4126fa4861c627c6aa8eca8ede8d43fb9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8747607469558716}",,,,,,,,,,['neutral'],neutral,1 NCT03197935,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-022-00457-3', 'title': 'Patient-reported outcomes from a randomized trial of neoadjuvant atezolizumab-chemotherapy in early triple-negative breast cancer', 'source': 'Nature', 'date': 'Sep 19, 2022', 'snippet': 'These patient-reported data inform clinical benefit and decision-making for \nadding atezolizumab to neoadjuvant chemotherapy in early-stage TNBC.', 'thumbnail': 'https://serpapi.com/searches/6721bc44ca6f0c61948101f3/images/887d801f34e0fd9377681693f14fb3d79df90c606ecfa49869b19131c0508878.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8834286332130432}",,,,,,,,,,['neutral'],neutral,1 NCT03956355,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2103629', 'title': 'Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 8, 2021', 'snippet': 'Tapinarof cream is a topical aryl hydrocarbon receptor–modulating agent \nunder investigation for the treatment of psoriasis.', 'thumbnail': 'https://serpapi.com/searches/6721bd9849ea55cdb868e635/images/c01e7495a8fa9d3612cf094b681582d85259f706589aaaee69d0b1cb9de3d9ed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8930850028991699}","{'position': 2, 'link': 'https://www.dermatologytimes.com/view/tapinarof-cream-1-is-fda-approved', 'title': 'Tapinarof Cream 1% is FDA Approved', 'source': 'Dermatology Times', 'date': 'May 24, 2022', 'snippet': 'Tapinarof cream 1%, (Vtama; Dermavant Sciences) was approved by the FDA for \ntopical treatment of plaque psoriasis in adults.', 'thumbnail': 'https://serpapi.com/searches/6721bd9849ea55cdb868e635/images/c01e7495a8fa9d3642d0da2eb42df5487f9b70f7d6e0380483723dd2420f58d6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5443679094314575}","{'position': 3, 'link': 'https://www.pharmacypracticenews.com/FDA-Approvals/Article/05-22/FDA-Approves-First-Steroid-Free-Cream-for-Plaque-Psoriasis/67058?ses=ogst', 'title': 'FDA Approves First Steroid-Free Cream for Plaque Psoriasis', 'source': 'Pharmacy Practice News', 'date': 'May 24, 2022', 'snippet': 'With the approval of tapinarof (Vtama, Dermavant) cream, the FDA allowed \nthe marketing of the first steroid-free topical medication for the \ntreatment of adults...', 'thumbnail': 'https://serpapi.com/searches/6721bd9849ea55cdb868e635/images/c01e7495a8fa9d36cb93236c604763ade089de500e3812e9baeaf82ba93488fc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6624809503555298}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT01928576,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02267-1', 'title': 'Phase I/II sequencing study of azacitidine, epacadostat, and pembrolizumab in advanced solid tumors', 'source': 'Nature', 'date': 'Apr 22, 2023', 'snippet': 'We evaluated whether epigenetic therapy plus IDO1 inhibition and immune \ncheckpoint blockade confers clinical benefit to patients with advanced \nsolid tumors.', 'thumbnail': 'https://serpapi.com/searches/6721bdc27ac73169f8525bea/images/2d8b3bc0f5b55b216b39bef7d0c592baeed9c35535ec9b08fdb4bc53a9ae6b75.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8710958957672119}",,,,,,,,,,['neutral'],neutral,1 NCT00634270,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-0903-x', 'title': 'Translating current basic research into future therapies for neurofibromatosis type 1', 'source': 'Nature', 'date': 'May 22, 2020', 'snippet': 'Neurofibromatosis type 1 (NF1) is a hereditary tumour syndrome that \npredisposes to benign and malignant tumours originating from neural...', 'thumbnail': 'https://serpapi.com/searches/6721be3e993688eab341f3d0/images/43e1efcb9ba5aa049061f5aa7d2cffd708527404179ba39ab5ee2c4c048b8081.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.803081214427948}",,,,,,,,,,['neutral'],neutral,1 NCT03493932,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-024-01226-x', 'title': 'Immunotherapy for glioblastoma: current state, challenges, and future perspectives | Cellular & Molecular Immunology', 'source': 'Nature', 'date': '2 weeks ago', 'snippet': 'Glioblastoma (GBM) is an aggressive and lethal type of brain tumor in human \nadults. The standard of care offers minimal clinical benefit,...', 'thumbnail': 'https://serpapi.com/searches/6721be5615c740ab121e3508/images/ffe5a6176753904aceff903155209921eee5fee501454c0779fc7f6f1e6d1046.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7423284649848938}",,,,,,,,,,['negative'],negative,0 NCT00106535,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-70942-x', 'title': 'Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis', 'source': 'Nature', 'date': 'Aug 18, 2020', 'snippet': 'The aim of this study was to identify variation in Disease Activity Score \n28 (DAS28) of RA patients in response to Tocilizumab, and to investigate \nboth...', 'thumbnail': 'https://serpapi.com/searches/6721be71717bffe9341979e6/images/e4ca0b8dff55e502bdc307a3c60cf58ee655575a5ef762d32803016a80107f1a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9106734991073608}",,,,,,,,,,['neutral'],neutral,1 NCT04874948,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1155/2022/5099312', 'title': 'Advances in Key Drug Target Identification and New Drug Development for Tuberculosis', 'source': 'Wiley Online Library', 'date': 'Feb 25, 2022', 'snippet': 'In this review, we summarized 45 important drug targets and 15 new drugs \nthat are currently being tested in clinical stages and several prospective \nmolecules.', 'thumbnail': 'https://serpapi.com/searches/6721be74e281ee51ad5bac09/images/61f676097a97963019c2dbb6bcb6938774fdfd13d38aa4cf89ba1d893426b889.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7801258563995361}",,,,,,,,,,['neutral'],neutral,1 NCT03712423,"{'position': 1, 'link': 'https://www.nature.com/articles/d43747-020-00674-4', 'title': 'A clinical-phase cancer biotech with nanomedicine partnering opportunities', 'source': 'Nature', 'date': 'Sep 1, 2020', 'snippet': 'Cristal Therapeutics is improving the treatment options for patients with a \nrange of solid tumors by creating transiently stable nanomedicines.', 'thumbnail': 'https://serpapi.com/searches/6721bec081262aaa2f008621/images/ebe08c868125eb05ea4211db545a09dd48b7391491e37a927005d05d82db916b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6484225392341614}",,,,,,,,,,['positive'],positive,1 NCT02894008,"{'position': 1, 'link': 'https://www.europeanpharmaceuticalreview.com/news/151155/novel-leishmaniasis-vaccine-safely-induces-immune-responses-in-patients/', 'title': 'Novel leishmaniasis vaccine safely induces immune responses in patients', 'source': 'European Pharmaceutical Review', 'date': 'Apr 16, 2021', 'snippet': 'ChAd63-KH, used to treat leishmaniasis rather than prevent in this trial, \nimproved symptoms in patients with dermal leishmaniasis.', 'thumbnail': 'https://serpapi.com/searches/6721becfc821270c41794a3f/images/4128ee0abee92b446c0cfefee98ad0bfa9fa6b395599cef4be1f187764e2d968.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5359059572219849}",,,,,,,,,,['neutral'],neutral,1 NCT00593242,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-61311-9', 'title': 'Autologous cord blood cell therapy for neonatal hypoxic-ischaemic encephalopathy: a pilot study for feasibility and safety | Scientific Reports', 'source': 'Nature', 'date': 'Mar 12, 2020', 'snippet': 'We conducted a single-arm clinical study to examine the feasibility and \nsafety of intravenous infusion of autologous UCBCs for newborns with HIE.', 'thumbnail': 'https://serpapi.com/searches/6721bed148c429afb9567c7a/images/e451b5484c9b47133c27b2daed4aa5897fc623c2a5e4e9ee71ac9e5c9632af71.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9104992151260376}",,,,,,,,,,['neutral'],neutral,1 NCT03616223,"{'position': 1, 'link': 'https://www.genengnews.com/topics/translational-medicine/astellas-frequency-therapeutics-partner-to-develop-hearing-loss-drug/', 'title': 'Astellas, Frequency Therapeutics Partner to Develop Hearing Loss Drug', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Jul 18, 2019', 'snippet': ""Astellas Pharma will partner with Frequency Therapeutics to develop \nFrequency's lead candidate—the Phase IIa-bound sensorineural hearing..."", 'thumbnail': 'https://serpapi.com/searches/6721bed84a4a1d50e1852ad6/images/78d0bda4120ff4d7050368665402f318639e2b0ca9c47f410a1656d6b8deea3a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9010204672813416}",,,,,,,,,,['neutral'],neutral,1 NCT00832039,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-018-19976-w', 'title': 'Early immune anergy towards recall antigens and mitogens in patients at onset of septic shock', 'source': 'Nature', 'date': 'Jan 29, 2018', 'snippet': 'The pathology of sepsis is typically characterized by an infection and \nexcessive initial inflammation including a cytokine storm,...', 'thumbnail': 'https://serpapi.com/searches/6721bf1fe1d1ad8e5c016171/images/8a3073f5a7ae3358078bf0c6c200431cc6702e1125dbeefa22d6d25b08adf9e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5468384623527527}",,,,,,,,,,['neutral'],neutral,1 NCT03764488,"{'position': 1, 'link': 'https://alsnewstoday.com/news/fda-expected-decide-tofersen-approval-sod1-als-january/', 'title': 'FDA Expected to Decide on Tofersen Approval for SOD1-ALS in January', 'source': 'ALS News Today', 'date': 'Jul 27, 2022', 'snippet': ""The US Food and Drug Administration (FDA) has agreed to review an \napplication from Biogen for approval of the company's experimental therapy \ntofersen."", 'thumbnail': 'https://serpapi.com/searches/6721bf227b05caf824e9f8ec/images/1f8a20937a9b73de826336f58d93837cf74e3138d0dcd961552473b69a469ad3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8993838429450989}",,,,,,,,,,['neutral'],neutral,1 NCT03777176,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/dasiglucagon-under-priority-review-for-hypoglycemia-in-congenital-hyperinsulinism/', 'title': 'Dasiglucagon Gets Priority Review for Hypoglycemia in Congenital Hyperinsulinism', 'source': 'Medical Professionals Reference', 'date': 'Aug 30, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted for Priority Review the \nNew Drug Application (NDA) for dasiglucagon for the prevention...', 'thumbnail': 'https://serpapi.com/searches/6721bf36a505f73e95b9f123/images/7f8c7bd2022029100051f8808cec05ab649f84cd8a9ead4ea4a29107554e53db.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8679986596107483}",,,,,,,,,,['neutral'],neutral,1 NCT02273739,"{'position': 1, 'link': 'https://blogs.bmj.com/bmj/2019/11/05/unreported-trial-of-the-week-orally-administered-ag-221-in-subjects-with-advanced-solid-tumours-nct02273739/', 'title': 'Unreported clinical trial of the week: Enasidenib for use in advanced solid tumors (NCT02273739)', 'source': 'BMJ Blogs', 'date': 'Nov 5, 2019', 'snippet': 'While Enasidenib is currently only approved in a specific form of leukemia, \nthe IDH-2 mutation it targets also occurs in a variety of solid...', 'thumbnail': 'https://serpapi.com/searches/6721bf3e175de6645df64237/images/5ad31bb586d258852986272e8679e3ac975da94a577dad3b748234c210e75c9d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9006510376930237}",,,,,,,,,,['neutral'],neutral,1 NCT04140123,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-42162-0', 'title': 'ZSP1601, a novel pan-phosphodiesterase inhibitor for the treatment of NAFLD, A randomized, placebo-controlled phase Ib/IIa trial', 'source': 'Nature', 'date': 'Oct 12, 2023', 'snippet': 'Non-alcoholic fatty liver disease is a growing health burden with limited \ntreatment options worldwide. Herein we report a randomized,...', 'thumbnail': 'https://serpapi.com/searches/6721bf5cf8b05d603f2559c0/images/0592743749ff108703a93806e8283c00cb0ed149b76579feabac8dfe4a8e0fcd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8327338695526123}",,,,,,,,,,['neutral'],neutral,1 NCT04998201,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2404143', 'title': 'Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia', 'source': 'The New England Journal of Medicine', 'date': 'May 28, 2024', 'snippet': 'Persons with mixed hyperlipidemia are at risk for atherosclerotic \ncardiovascular disease due to an elevated non–high-density lipoprotein...', 'thumbnail': 'https://serpapi.com/searches/6721bf6ba5e50295eeffbad7/images/e9e18597c13304478f2c041317e7e7cd05d3a98768ce4f6f3a71af30b99a0521.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7325981259346008}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/circ.148.suppl_1.17091', 'title': 'Abstract 17091: ARO-APOC3, an Investigational RNAi Therapeutic, Silences APOC3 and Reduces Atherosclerosis-Associated Lipoproteins in Patients With Mixed Dyslipidemia: MUIR Study Results', 'source': 'American Heart Association Journals', 'date': 'Nov 6, 2023', 'snippet': 'Background: Despite the availability of potent LDL-C-lowering therapies, \npatients with mixed dyslipidemia (MD) remain at high risk of...', 'thumbnail': 'https://serpapi.com/searches/6721bf6ba5e50295eeffbad7/images/e9e18597c1330447094a7861db7cb286993e3db3bc2636907189bf9b1844be16.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8766289353370667}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02276027,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222015724', 'title': 'Synergistic therapeutic potential of alpelisib in cancers (excluding breast cancer): Preclinical and clinical evidences', 'source': 'ScienceDirect.com', 'date': 'Jan 14, 2023', 'snippet': 'Alpelisib, a selective 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'sentiment': 'neutral', 'sentiment_prob': 0.8610352277755737}",,,,,,,,,,['neutral'],neutral,1 NCT00063999,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.20.01076', 'title': 'Carboplatin and Paclitaxel for Advanced Endometrial Cancer: Final Overall Survival and Adverse Event Analysis of a Phase III Trial (NRG Oncology/GOG0209) | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Mar 17, 2021', 'snippet': 'GOG0209 was a phase III, randomized, noninferiority, open-label trial. \nInclusion criteria were stage III, stage IV, and recurrent endometrial \ncancers;...', 'thumbnail': 'https://serpapi.com/searches/6721bfdd0197dd056176d680/images/5564374b129abbbf81b50f32ce8f572d043e47341ca9afc306bb708f2a70169b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9077574014663696}","{'position': 2, 'link': 'https://www.onclive.com/view/dr-mirza-on-the-fda-approval-of-dostarlimab-plus-chemotherapy-in-dmmr-msi-h-endometrial-cancer', 'title': 'Dr Mirza on the FDA Approval of Dostarlimab Plus Chemotherapy in dMMR/MSI-H Endometrial Cancer', 'source': 'OncLive', 'date': 'Jul 31, 2023', 'snippet': 'The FDA approved dostarlimab plus carboplatin and paclitaxel followed by \ndostarlimab monotherapy for adult patients with dMMR or MSI-H primary \nadvanced or...', 'thumbnail': 'https://serpapi.com/searches/6721bfdd0197dd056176d680/images/5564374b129abbbf63e4d49b6c751aa36888f3a7a6159740e7c61fbfc2edcebe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8453629016876221}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03683498,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-12407-x', 'title': 'Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib', 'source': 'Nature', 'date': 'May 19, 2022', 'snippet': 'The combination of ruxolitinib with Treg showed a higher efficacy as \ncompared to each single treatment alone in our GvHD mouse model in terms of \nGvHD incidence...', 'thumbnail': 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'sentiment': 'neutral', 'sentiment_prob': 0.5324159860610962}",,,,,,,,,,['neutral'],neutral,1 NCT03781804,"{'position': 1, 'link': 'https://www.pennmedicine.org/news/news-releases/2024/january/exhalation-system-improves-symptoms-of-chronic-sinus-infections', 'title': ""'Exhalation' System Improves Symptoms of Chronic Sinus Infections"", 'source': 'Penn Medicine', 'date': 'Jan 18, 2024', 'snippet': ""An exhalation delivery system that uses a patient's own breath to carry the \nanti-inflammatory compound fluticasone (EDS-FLU) directly to the sinuses \nreduced..."", 'thumbnail': 'https://serpapi.com/searches/6721c056b5ecbb5708920dfc/images/04c0368bbfc13c79648d9858d11ce16ec6864c6b3b91c1d71585b33b463593ae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8489072918891907}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/drug-device-combo-looks-promising-for-chronic-sinusitis/', 'title': 'Drug-Device Combo Looks Promising for Chronic Sinusitis', 'source': 'Medical Professionals Reference', 'date': 'Mar 7, 2022', 'snippet': 'Positive topline results were announced from a phase 3 trial evaluating the \nintranasal administration of OPN-375 (fluticasone propionate) in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/6721c056b5ecbb5708920dfc/images/04c0368bbfc13c7917a4ab2cf83c6947e3cbfe38cf03d641af7da6699f74b43a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7450494766235352}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT03425539,"{'position': 1, 'link': 'https://fabrydiseasenews.com/news/idorsia-continues-lucerastat-extension-study-long-ter-kidney-heart-benefits/', 'title': 'Lucerastat Extension Trial Will Continue, Focus on Long-term Possibilities', 'source': 'Fabry Disease News', 'date': 'Jan 21, 2022', 'snippet': 'While lucerastat failed in Phase 3 MODIFY trial to ease neuropathic pain, \npossible kidney and cardiac gains merit closer look, Idorsia says.', 'thumbnail': 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interleukin-12 and interleukin-23,..."", 'thumbnail': 'https://serpapi.com/searches/6721c0a3cc48791ec6d36218/images/3e369c0cd3f587ec9d9c27ddd13ad633339d9d9b9d13e75c08c7719579ceb2c1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8811381459236145}",,,,,,,,,,['neutral'],neutral,1 NCT00893373,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-021-01148-x', 'title': 'Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial', 'source': 'Nature', 'date': '١٨\u200f/٠٢\u200f/٢٠٢١', 'snippet': 'Early results of the randomized placebo-controlled SORAML trial showed \nthat, in patients with newly diagnosed acute myeloid leukaemia (AML),...', 'thumbnail': 'https://serpapi.com/searches/6721c0a4d72128f26f325323/images/3977ffaa311d58b0cf33b38f1b91546eb3e1aadb868b8f1281693cfeca99aad4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.924304723739624}",,,,,,,,,,['neutral'],neutral,1 NCT02955550,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/pnk-007-treatment-after-stem-cell-transplant-leads-to-good-response-rates-in-multiple-myeloma-patients-early-trial-data-show/', 'title': 'Myeloma Patients Respond Well to PNK-007 After Transplant, Data Show', 'source': 'Myeloma Research News', 'date': 'Jan 8, 2020', 'snippet': ""A single infusion of Celularity's PNK-007 — an investigational cell therapy \nderived from placental stem cells — is safe and leads to good..."", 'thumbnail': 'https://serpapi.com/searches/6721c0b7361fd4c8c0465eb8/images/d87c9dc05b02e0e9177d0bfaf9938f9c90f35ddd5293397c31a50152184e083f.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7810468673706055}",,,,,,,,,,['positive'],positive,1 NCT02968004,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/reports/somatrogon-4-year-efficacy-safety-pediatric-growth-hormone-deficiency/', 'title': 'Somatrogon Yields 4-Year Efficacy, Safety in Pediatric Growth Hormone Deficiency', 'source': 'Endocrinology Advisor', 'date': 'May 9, 2024', 'snippet': 'Children with pediatric growth hormone deficiency (pGHD) demonstrated \ncatch-up growth and mean height gain after 4 years of somatrogon treatment.', 'thumbnail': 'https://serpapi.com/searches/6721c0bb51d84d1f0a6ed8ea/images/16e83c2d842ebb38a5651c337e8f51630e67cad3757dbb51be497952c8316f64.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6659769415855408}",,,,,,,,,,['neutral'],neutral,1 NCT01634750,"{'position': 1, 'link': 'https://www.nature.com/articles/s41436-021-01259-x', 'title': 'Safety and efficacy of N -acetylmannosamine (ManNAc) in patients with GNE myopathy: an open-label phase 2 study', 'source': 'Nature', 'date': 'Jul 13, 2021', 'snippet': 'ManNAc showed long-term safety, biochemical efficacy consistent with the \nintended mechanism of action, and preliminary evidence clinical efficacy in \npatients...', 'thumbnail': 'https://serpapi.com/searches/6721c0d48e13c9f8fd73628a/images/9ca73ceb4e8c6a3757ca030c0cf79e9ed9546f7918599c21eef31b532d61cbcd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6594723463058472}",,,,,,,,,,['neutral'],neutral,1 NCT02096289,"{'position': 1, 'link': 'https://www.nature.com/articles/tpj201676', 'title': 'A systems biology approach to investigate the mechanism of action of trabectedin in a model of myelomonocytic leukemia', 'source': 'Nature', 'date': 'Dec 13, 2016', 'snippet': 'This study was designed to investigate the mode of action of trabectedin in \nmyelomonocytic leukemia cells by applying systems biology...', 'thumbnail': 'https://serpapi.com/searches/6721c0f8d364b4c6b6b0e871/images/b6ce3f4a32b142d90b216e42f34b9f47234f105db4d15c3e88993a92544811cc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9292907118797302}",,,,,,,,,,['neutral'],neutral,1 NCT03926819,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/low-dose-carbon-monoxide-may-protect-neurons-with-parkinsons/', 'title': 'Low-dose carbon monoxide may protect neurons, much like smoking', 'source': ""Parkinson's News Today"", 'date': 'Aug 28, 2024', 'snippet': 'A rat model study found an oral form of carbon monoxide called HBI-002 \n(tested for safety in Phase 1 trial) promoted neuron survival,...', 'thumbnail': 'https://serpapi.com/searches/6721c11ab9458d9fbfbd9ae9/images/66da93253a85c2dac1c29110dd1f96ea098823c9e336e8d452c8dbc3d91402ae.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6187165379524231}",,,,,,,,,,['neutral'],neutral,1 NCT04770935,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-hengrui-medicine-triple-negative-breast-cancer/', 'title': 'Pipeline Moves: Hengrui Medicine Phase III breast cancer termination lowers approval prospects', 'source': 'Clinical Trials Arena', 'date': 'May 16, 2023', 'snippet': 'The Clinical Trials Arena team also review assets in the central nervous \nsystem, cardiology, renal, haematological and other oncology...', 'thumbnail': 'https://serpapi.com/searches/6721c12c3c944b513039cd0e/images/b9b643e96af3ec4650d63983fa4e61eb2429b03694fa6f3376853ad0ff800bf2.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6495799422264099}",,,,,,,,,,['negative'],negative,0 NCT02799095,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2020/11/24/alks-4230-keytruda-combo-found-to-halt-disease-progression-reduce-tumor-size-among-ovarian-cancer-patients-in-phase-1-2-trial/', 'title': 'ALKS 4230-Keytruda Combo Found to Reduce Tumor Size, Halt Disease Progression', 'source': 'Ovarian Cancer News Today', 'date': 'Nov 24, 2020', 'snippet': 'An ALKS 4230-Keytruda combo was able to halt disease progression and reduce \ntumor size in women with advanced ovarian cancer,...', 'thumbnail': 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'title': 'For gMG, Chinese regulators agree to consider approving batoclimab...', 'source': 'Myasthenia Gravis News', 'date': 'Jul 11, 2023', 'snippet': 'Submitted as a biologics license application, the request to review \nbatoclimab is buoyed by positive top-line data from a Phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/6721c145d997ab91c9b28661/images/48373cfd3ee1d95ede623390d8e2802ed9f533156859b69bc15179d9c1b0dd9b.png', 'sentiment': 'positive', 'sentiment_prob': 0.6625019907951355}",,,,,,,,,"['positive', 'positive']",positive,1 NCT04084769,"{'position': 1, 'link': 'https://www.nature.com/articles/s41390-023-02478-5', 'title': 'Quadrivalent meningococcal tetanus toxoid-conjugate booster vaccination in adolescents and adults: phase III randomized study', 'source': 'Nature', 'date': 'Mar 10, 2023', 'snippet': 'The immunogenicity and safety of a booster dose of tetanus toxoid-conjugate \nquadrivalent meningococcal vaccine (MenACYW-TT),...', 'thumbnail': 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'Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer', 'source': 'Nature', 'date': 'Sep 16, 2020', 'snippet': 'Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. \nDue to their HLA-independent mode of action, allogeneic Vγ9Vδ2 T...', 'thumbnail': 'https://serpapi.com/searches/6721c1eb2e33c8f507281b6a/images/41042e290cde505d5fa2cca0b4d2166fcce1b15ad7263c533a5bbbbc5b4e6429.png', 'sentiment': 'positive', 'sentiment_prob': 0.7890372276306152}",,,,,,,,,,['positive'],positive,1 NCT03505099,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01866-4', 'title': 'Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: the Phase III SPR1NT trial', 'source': 'Nature', 'date': 'Jun 17, 2022', 'snippet': 'SPR1NT ( NCT03505099 ) was a Phase III, multicenter, single-arm study to \ninvestigate the efficacy and safety of onasemnogene abeparvovec for...', 'thumbnail': 'https://serpapi.com/searches/6721c20d237938d0baf98d04/images/bf1675363e2c64441d5121bdf0575f1fd8fe9a1fc6a6c538e36aec0d5fdde2b2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8673272728919983}","{'position': 2, 'link': 'https://www.empr.com/home/news/onasemnogene-abeparvovec-xioi-zolgensma-age-development-in-spinal-muscular-dystrophy/', 'title': 'Zolgensma Benefits Observed in Presymptomatic SMA Patients', 'source': 'Medical Professionals Reference', 'date': 'Mar 15, 2021', 'snippet': 'Early treatment with onasemnogene abeparvovec-xioi led to age-appropriate \ndevelopment in patients with spinal muscular atrophy.', 'thumbnail': 'https://serpapi.com/searches/6721c20d237938d0baf98d04/images/bf1675363e2c6444526629088c90ab7c4a8725d0c26b95a44f89fc5239bdb8ec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7931104898452759}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01720446,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1607141', 'title': 'Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Sep 16, 2016', 'snippet': 'The rate of cardiovascular death, nonfatal myocardial infarction, or \nnonfatal stroke was significantly lower among patients receiving \nsemaglutide than among...', 'thumbnail': 'https://serpapi.com/searches/6721c25bfda26de13edfd712/images/5cf641c896a1f8623af0bf94df3008f576855f8fbba0b6deb2ec33ae871e00e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7180549502372742}","{'position': 2, 'link': 'https://www.endocrinologyadvisor.com/cch/sglt2-inhibitors-glp1-agonists-patients-with-t2dm-and-previous-cvd-high-risk-of-mace/', 'title': 'Reducing Risk of Major Adverse Cardiovascular Events: Role of SGLT2 Inhibitors, GLP-1 Agonists', 'source': 'Endocrinology Advisor', 'date': 'May 17, 2024', 'snippet': 'Patients with type T2DM and previous cardiovascular disease are at high \nrisk of MACE. This article focuses on how SGLT2 inhibitors and GLP-1 \nagonists,...', 'thumbnail': 'https://serpapi.com/searches/6721c25bfda26de13edfd712/images/5cf641c896a1f8626d014a31cd670a4c6896828b965ba60f095f39c2d54f0fc4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8390507698059082}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02049866,"{'position': 1, 'link': 'https://www.nature.com/articles/srep22378', 'title': 'Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption', 'source': 'Nature', 'date': 'Mar 2, 2016', 'snippet': 'CypA (Cyclophilin A) is a peptidyl-prolyl isomerase previously shown to be \nrequired for chondrogenic differentiation and endochondral ossification.', 'thumbnail': 'https://serpapi.com/searches/6721c25de8735a1451f2b72b/images/edfb161e4cf3295a6aec5070de48c21e344480a153549dc73b032990d1145794.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8983614444732666}",,,,,,,,,,['neutral'],neutral,1 NCT03761784,"{'position': 1, 'link': 'https://www.dermatologytimes.com/view/twyneo-receives-fda-approval-for-acne', 'title': 'Twyneo Receives FDA Approval for Acne', 'source': 'Dermatology Times', 'date': 'Jul 27, 2021', 'snippet': 'Twyneo, a tretinoin and benzoyl peroxide cream, has been approved by the \nFDA for the treatment of acne vulgaris in patients 9 years and...', 'thumbnail': 'https://serpapi.com/searches/6721c273b28e6b3deb75b7b4/images/f891b367931fd9ebf1976d618c0361644c4cacdcde7be438e4fb016172c1095d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.640620231628418}","{'position': 2, 'link': 'https://www.empr.com/home/news/galderma-announces-launch-of-twyneo-cream-for-acne-vulgaris/', 'title': 'Galderma Announces Launch of Twyneo Cream for Acne Vulgaris', 'source': 'Medical Professionals Reference', 'date': 'Mar 25, 2022', 'snippet': 'Galderma has announced the US launch of Twyneo (tretinoin 0.1% and benzoyl \nperoxide 3%) cream for the topical treatment of acne vulgaris in patients 9 \nyears of...', 'thumbnail': 'https://serpapi.com/searches/6721c273b28e6b3deb75b7b4/images/f891b367931fd9eb2aaa6aba9612a621fc667a87b057453467a12813d24e2edb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8534439206123352}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03899480,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1084109/full', 'title': 'Prospects for NK-based immunotherapy of chronic HBV infection', 'source': 'Frontiers', 'date': 'Feb 21, 2024', 'snippet': 'Effective and long-term treatment is required for controlling chronic \nHepatitis B Virus (HBV) infection. Natural killer (NK) cells are antiviral \ninnate...', 'thumbnail': 'https://serpapi.com/searches/6721c2a4d169156d0d06b3b2/images/92a9a3d62c8139cf2335258eed38943776fd46659ecc6fb16bb9e577614aa321.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8224900364875793}",,,,,,,,,,['neutral'],neutral,1 NCT03635567,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2112435', 'title': 'Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 18, 2021', 'snippet': 'In a double-blind, phase 3 trial, we randomly assigned patients with \npersistent, recurrent, or metastatic cervical cancer in a 1:1 ratio to...', 'thumbnail': 'https://serpapi.com/searches/6721c2ac717bffe934197cd4/images/c3dd33ef9b5ff7fd9a958024e094b460e2b3cf925ca9b6400ca415159de6d6b1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8948957920074463}","{'position': 2, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00052-9/fulltext', 'title': 'Health-related quality of life with pembrolizumab or placebo plus chemotherapy with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer (KEYNOTE-826): a randomised, double-blind, placebo-controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'Mar 3, 2023', 'snippet': 'In the KEYNOTE-826 study, the addition of the anti-PD-1 monoclonal antibody \npembrolizumab to chemotherapy with or without bevacizumab...', 'thumbnail': 'https://serpapi.com/searches/6721c2ac717bffe934197cd4/images/c3dd33ef9b5ff7fd50f305978fbb05b01f06527b40713255c0c3bcc2f7e39792.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8319631814956665}","{'position': 3, 'link': 'https://www.empr.com/home/news/keytruda-approved-as-first-line-treatment-for-persistent-recurrent-or-metastatic-cervical-cancer/', 'title': 'Keytruda Approved as First-Line Treatment for Persistent, Recurrent or Metastatic Cervical Cancer', 'source': 'Medical Professionals Reference', 'date': 'Oct 13, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Keytruda \n(pembrolizumab) in combination with chemotherapy, with or without \nbevacizumab,...', 'thumbnail': 'https://serpapi.com/searches/6721c2ac717bffe934197cd4/images/c3dd33ef9b5ff7fd91ac8a802dae4258ee5c2a4aeee3fa10d1725c5e6a209ead.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8480886220932007}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01876511,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1500596', 'title': 'PD-1 Blockade in Tumors with Mismatch-Repair Deficiency', 'source': 'The New England Journal of Medicine', 'date': 'May 30, 2015', 'snippet': 'This study showed that mismatch-repair status predicted clinical benefit of \nimmune checkpoint blockade with pembrolizumab.', 'thumbnail': 'https://serpapi.com/searches/6721c2b2f9f904883974f02a/images/41897cdc5b21335573b27ed0b22bd50c10876ecb7ead2cb33cbfb14417411647.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8608921766281128}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-020-17386-z', 'title': 'Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival', 'source': 'Nature', 'date': 'Jul 20, 2020', 'snippet': 'This large study provides deep insights into somatic mutations in CRC, and \ntheir potential relationships with survival and tumor features.', 'thumbnail': 'https://serpapi.com/searches/6721c2b2f9f904883974f02a/images/41897cdc5b21335507e4a32b9166674659a3269b8a7ea0667d100daa21dcf733.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9113010168075562}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03910543,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-30615-x', 'title': 'Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis', 'source': 'Nature', 'date': 'Jun 6, 2022', 'snippet': 'Our results thus show that tofacitinib treatment is associated with \nimproved sarcoidosis symptoms, and predominantly acts by inhibiting type 1 \nimmunity.', 'thumbnail': 'https://serpapi.com/searches/6721c2b475f974f2da18b3bd/images/e39d607948cdbf0603a9ec7e87ddfd32c2851a8df18892ce49ace5eefc70c74f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8527399897575378}",,,,,,,,,,['neutral'],neutral,1 NCT04304534,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061612', 'title': 'A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction | Circulation', 'source': 'American Heart Association Journals', 'date': 'Aug 30, 2022', 'snippet': 'We explored the pharmacodynamics, safety, and efficacy of the oral FXIa \ninhibitor asundexian for secondary prevention after acute myocardial \ninfarction (MI).', 'thumbnail': 'https://serpapi.com/searches/6721c2bc9e38e52c96d87599/images/a27d81a07ab1eb726501b914ceeac9b211eb8ce45e3d0e58a8816bd270d61fea.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8496591448783875}",,,,,,,,,,['neutral'],neutral,1 NCT02962895,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02251-0/abstract?uuid=uuid%3Abf64494f-0e46-4f5c-8218-999221045e2d', 'title': ""Safety and efficacy of subcutaneous ianalumab (VAY736) in patients with primary Sjögren's syndrome: a randomised, double-blind, placebo-controlled, phase 2b dose-finding trial"", 'source': 'The Lancet', 'date': 'Nov 30, 2021', 'snippet': ""Sjögren's syndrome is an autoimmune disease characterised by dry eyes and \nmouth, systemic features, and reduced quality of life."", 'thumbnail': 'https://serpapi.com/searches/6721c2bd51d84d1ed7a570af/images/89d893b6f740fa7028f1462b34cd3c2a725f7d03f8fc696cca88356f6ebc073c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7355638146400452}","{'position': 2, 'link': 'https://sjogrenssyndromenews.com/news/ianalumab-vay736-eases-sjogrens-symptoms-over-year-phase-2b-trial/', 'title': 'Ianalumab Safely Lowers Sjögren Activity at High Dose in Clinical Trial', 'source': ""Sjogren's Syndrome News"", 'date': 'Nov 9, 2021', 'snippet': 'The antibody was well-tolerated over 52 weeks in Phase 2b trial, increasing \nsalivary gland production as once-monthly 300 mg injection.', 'thumbnail': 'https://serpapi.com/searches/6721c2bd51d84d1ed7a570af/images/89d893b6f740fa7041d8f7e5d00295e701a1f69a4ba7d70cd2ee8653cc11271f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4982258677482605}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04964986,"{'position': 1, 'link': 'https://www.hcplive.com/view/apraglutide-reduces-parenteral-support-dependency-in-patients-with-sbs-if-cic', 'title': 'Apraglutide Reduces Parenteral Support Dependency in Patients with SBS-IF, CIC', 'source': 'HCPLive', 'date': 'Oct 19, 2023', 'snippet': 'Final data from STARS Nutrition were presented at United European \nGastroenterology Week 2023, demonstrating a significant reduction in...', 'thumbnail': 'https://serpapi.com/searches/6721c2da2bab902c966219fa/images/371ff0a7838c6d58311418a962f029d2fad4728b753f0dd39546bf03643be4ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7994058132171631}",,,,,,,,,,['neutral'],neutral,1 NCT05392179,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Deglycosylation-analysis-of-rhodopsin-A-Example-blot-with-rhodopsin-mutation-N15S-P23H_fig3_333184115', 'title': 'Deglycosylation analysis of rhodopsin A. Example blot with rhodopsin...', 'source': 'ResearchGate', 'date': 'Aug 23, 2024', 'snippet': 'Download scientific diagram | Deglycosylation analysis of rhodopsin A. \nExample blot with rhodopsin mutation (N15S, P23H and WT transiently in \nCOS-1 cells),...', 'thumbnail': 'https://serpapi.com/searches/6721c308b57db8b81dcf878b/images/32d0e401f83045d17e220085784fd5bfe253e9843ce82066766bb2e95cb50bed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8983781933784485}",,,,,,,,,,['neutral'],neutral,1 NCT02309580,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-018-32634-5', 'title': 'Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma', 'source': 'Nature', 'date': 'Sep 21, 2018', 'snippet': 'Patients with peripheral T-cell lymphomas generally have poor clinical \noutcomes with conventional chemotherapy.', 'thumbnail': 'https://serpapi.com/searches/6721c33b400bd5bee739a2d1/images/e5197f390786103b96a8f40fb26142fabe12414463f624eefc67e2b7c79e5daf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7779208421707153}",,,,,,,,,,['neutral'],neutral,1 NCT02987543,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1911440', 'title': 'Olaparib for Metastatic Castration-Resistant Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Apr 28, 2020', 'snippet': 'Multiple loss-of-function alterations in genes that are involved in DNA \nrepair, including homologous recombination repair, are associated...', 'thumbnail': 'https://serpapi.com/searches/6721c35d2da1575f5eaf0ebe/images/89ef21c39b183d024960fa6ecb556302290a2a131112889427ff049d84963b0c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5854230523109436}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2022485', 'title': 'Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 20, 2020', 'snippet': ""Olaparib led to significantly longer imaging-based progression-free \nsurvival than the physician's choice of enzalutamide or abiraterone among \nmen with..."", 'thumbnail': 'https://serpapi.com/searches/6721c35d2da1575f5eaf0ebe/images/89ef21c39b183d0236791017bb5206c3032b536492186e1f3c79ee5fcec4ec18.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7363011240959167}","{'position': 3, 'link': 'https://prostatecancernewstoday.com/2020/12/10/canada-approves-lynparza-metastatic-crpc-specific-mutations/', 'title': 'Canada Approves Lynparza for Metastatic CRPC Patients With Certain Gene Mutations', 'source': 'Prostate Cancer News Today', 'date': 'Dec 10, 2020', 'snippet': 'Canada has approved Lynparza to treat men with metastatic \ncastration-resistant prostate cancer who carry mutations in the in BRCA or \nATM...', 'thumbnail': 'https://serpapi.com/searches/6721c35d2da1575f5eaf0ebe/images/89ef21c39b183d0211e6df73ec7ee8700cd87b4fd0725ea3a037dbcae3fb0ecc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8830963373184204}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01109095,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1113882/full', 'title': 'The current landscape of CAR T-cell therapy for solid tumors: Mechanisms, research progress, challenges, and counterstrategies', 'source': 'Frontiers', 'date': 'Feb 6, 2024', 'snippet': 'The successful outcomes of chimeric antigen receptor (CAR) T-cell therapy \nin treating hematologic cancers have increased the previously \nunprecedented...', 'thumbnail': 'https://serpapi.com/searches/6721c37dd78a989f43d3e960/images/e67ba41c436526460cc959f3625f99395d0792ea1ba1320756343eb512bf609f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8026973009109497}","{'position': 2, 'link': 'https://www.nature.com/articles/s41698-021-00233-9', 'title': 'GD2 CAR T cells against human glioblastoma', 'source': 'Nature', 'date': 'Oct 27, 2021', 'snippet': 'Glioblastoma is the most malignant primary brain tumor and is still in need \nof effective medical treatment. We isolated patient-derived...', 'thumbnail': 'https://serpapi.com/searches/6721c37dd78a989f43d3e960/images/e67ba41c43652646d424d4f9aaf6dc1b18598fea85860f0ceb972d41f842a242.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7944258451461792}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT05818306,"{'position': 1, 'link': 'https://dravetsyndromenews.com/news/bl-001-therapy-live-gut-microbes-fares-well-healthy-adults/', 'title': 'Therapy based on live gut microbes fares well in healthy adults in trial', 'source': 'Dravet Syndrome News', 'date': 'Aug 22, 2023', 'snippet': 'BL-001, an oral live biotherapeutic for Dravet syndrome, was well-tolerated \nacross multiple-ascending doses in healthy adults, data show.', 'thumbnail': 'https://serpapi.com/searches/6721c3a13103006402ae39f9/images/4a4c8149ca4a909b8f866ea641ee68a9de25c7c9c4196d09873255a2a544772f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5160338878631592}",,,,,,,,,,['neutral'],neutral,1 NCT01450124,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-65215-6', 'title': 'Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis', 'source': 'Nature', 'date': 'May 29, 2020', 'snippet': 'Oral treatment with an SFE significantly reduces 5-LO-derived LMs in RR-MS \npatients during an eight-month treatment period.', 'thumbnail': 'https://serpapi.com/searches/6721c3c58b7ba7a75605072f/images/01d9fb01658a599e16776420c607592604df87e8e28b7813daf28202a42b6324.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7867388725280762}",,,,,,,,,,['neutral'],neutral,1 NCT01689519,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1408868', 'title': 'Combined Vemurafenib and Cobimetinib in BRAF -Mutated Melanoma', 'source': 'The New England Journal of Medicine', 'date': 'Sep 29, 2014', 'snippet': 'This randomized phase 3 study evaluated the combination of the BRAF \ninhibitor vemurafenib and the MEK inhibitor cobimetinib.', 'thumbnail': 'https://serpapi.com/searches/6721c444cf32e0c291d20699/images/ee01076b7cf24cb56a92149e9667213bab72f4fdff70264f8110f89bbb75b2a5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9341273307800293}",,,,,,,,,,['neutral'],neutral,1 NCT03673943,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/61/6/890', 'title': '64Cu-DOTATATE PET/CT for Imaging Patients with Known or Suspected Somatostatin Receptor–Positive Neuroendocrine Tumors: Results of the First U.S. Prospective, Reader-Masked Clinical Trial', 'source': 'Journal of Nuclear Medicine', 'date': 'Jun 1, 2020', 'snippet': '64 Cu-DOTATATE PET/CT is a safe imaging technique that provides \nhigh-quality and accurate images at a dose of 148 MBq (4.0 mCi) for the \ndetection of...', 'thumbnail': 'https://serpapi.com/searches/6721c453b9ab865d2f765adf/images/236a74f67fbda82abe253bf4eddcfd16ca2149e3eed177130d34ff0e511015ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8963620662689209}",,,,,,,,,,['neutral'],neutral,1 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decline in \npeople with early-stage ALS, clinical trial data show.', 'thumbnail': 'https://serpapi.com/searches/6721c4f4f922f68abd6e5754/images/141b851e53eb83510f038019cfb3bb65b03cd848ee39e7f5e7be8aa2fda727c7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7989188432693481}","{'position': 2, 'link': 'https://alsnewstoday.com/news/high-dose-vitamin-b12-helpful-early-diagnosis/', 'title': 'ALS Prognosis May Improve with High-Dose Vitamin B12 if Given Early, Study Says', 'source': 'ALS News Today', 'date': 'Jan 17, 2019', 'snippet': 'High doses of vitamin B12 may improve outcomes in patients with amyotrophic \nlateral sclerosis (ALS) who are treated soon after diagnosis,...', 'thumbnail': 'https://serpapi.com/searches/6721c4f4f922f68abd6e5754/images/141b851e53eb83513b743f523aac13e5c38142345cabe8a82e24f6418b81fb83.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7574703097343445}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04077437,"{'position': 1, 'link': 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'Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Dec 28, 2006', 'snippet': 'Lapatinib, a tyrosine kinase inhibitor of human epidermal growth factor \nreceptor type 2 (HER2, also referred to as HER2/neu) and epidermal...', 'thumbnail': 'https://serpapi.com/searches/6721ca85a5d70237f1dfe29f/images/771d130d2a7a187e17fdde182918f1a77445d92a1fc14022deb187d114cbb3c4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8776703476905823}",,,,,,,,,,['neutral'],neutral,1 NCT00289978,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0909494', 'title': 'A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Jan 20, 2010', 'snippet': 'As compared with placebo, both doses of oral fingolimod improved the \nrelapse rate, the risk of disability progression, and end points on MRI.', 'thumbnail': 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'title': 'Pharnext working toward applications for PXT3003 approval', 'source': 'Charcot-Marie-Tooth News', 'date': 'Jan 3, 2024', 'snippet': 'Pharnext is analyzing clinical trial data that could support applications \nto approve PXT3003, a therapy candidate for CMT1A.', 'thumbnail': 'https://serpapi.com/searches/6721cb5f39e23248aec4f92b/images/4965ae3d532f65da2d666798f11f24355b228163335bc67e4da3da54541885fb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7428095936775208}","{'position': 3, 'link': 'https://charcot-marie-toothnews.com/news/high-dose-pxt3003-potential-safely-treat-cmt1a-phase-3-trial-data/', 'title': 'PXT3003 at High Dose Shows Potential to Safely Treat CMT1A in Phase 3 Trial', 'source': 'Charcot-Marie-Tooth News', 'date': 'Oct 22, 2021', 'snippet': 'Data from the PLEO-CMT Phase 3 trial of PXT3003 show promising gains and \ngood safety for Charcot–Marie–Tooth type 1A patients, study finds.', 'thumbnail': 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'Short-term PXT3003 Treatment Delays Disease Onset in Rat Model of CMT1A, Study Shows', 'source': 'Charcot-Marie-Tooth News', 'date': 'Jan 24, 2019', 'snippet': 'Two weeks of treatment with PXT3003 delayed disease onset, corrected motor \ndeficits, and improved dysregulated molecular pathways in a rat...', 'thumbnail': 'https://serpapi.com/searches/6721cb5f39e23248aec4f92b/images/4965ae3d532f65dacd8bf88afe7b33089ca3f36525f6b096c855d93347a749cd.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5911993980407715}","{'position': 6, 'link': 'https://charcot-marie-toothnews.com/experimental-treatments-for-charcot-marie-tooth-disease/', 'title': 'Charcot–Marie–Tooth Disease Experimental Therapies Are in the Works', 'source': 'Charcot-Marie-Tooth News', 'date': 'Sep 13, 2017', 'snippet': 'Several potential CMT therapies are being evaluated in clinical trials. \nPharnext developed PXT3003 to treat people with CMT type 1A, the most \ncommon form of...', 'thumbnail': 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'Aug 30, 2023', 'snippet': 'The Food and Drug Administration (FDA) has issued a Complete Response \nLetter (CRL) to Outlook Therapeutics regarding the Biologics License \nApplication (BLA)...', 'thumbnail': 'https://serpapi.com/searches/6721cbb8cb33d0118fb63c85/images/de09abc9896cdc43c36c55e59d5438ae85c244e5c7ceaeaab375e738c8d0b181.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8640140891075134}",,,,,,,,,,['neutral'],neutral,1 NCT02878330,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1913556', 'title': 'Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants', 'source': 'The New England Journal of Medicine', 'date': 'Jul 29, 2020', 'snippet': 'Respiratory syncytial virus (RSV) is the most common cause of lower \nrespiratory tract infection in infants, and a need exists for prevention...', 'thumbnail': 'https://serpapi.com/searches/6721cbf2caddc31d1631616c/images/d07f10d281400c51733e894bdc0354fab8a552d1b70ecd371de6f1de1bd8e386.png', 'sentiment': 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'link': 'https://www.nature.com/articles/bcj201718', 'title': 'Randomized phase 3 study of elotuzumab for relapsed or refractory multiple myeloma: ELOQUENT-2 Japanese patient subanalysis', 'source': 'Nature', 'date': 'Mar 10, 2017', 'snippet': 'A phase 3, international, randomized clinical trial that investigated the \nefficacy and safety of ELd compared with lenalidomide/dexamethasone (Ld) in \npatients...', 'thumbnail': 'https://serpapi.com/searches/6721cbf3db3ac9d20ba67b04/images/e974ffefcc928b6306835354747718bf59e6b6cfe4803cb91330cdfd31387f54.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9092058539390564}",,,,,,,,,,['neutral'],neutral,1 NCT04592484,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-024-06494-z', 'title': 'Roles of exosomes in immunotherapy for solid cancers', 'source': 'Nature', 'date': 'Feb 1, 2024', 'snippet': 'Exosomes are the main type of extracellular vesicles that can deliver \nvarious intracellular molecules to adjacent or distant cells 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NCT01325220,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/arbaclofen-improved-behavior-half-fragile-x-children-trial/', 'title': 'Arbaclofen Improved Behavior of Almost Half of Children in Phase 3 Trial', 'source': 'Fragile X News Today', 'date': 'Aug 19, 2022', 'snippet': 'The investigational fragile X therapy Arbaclofen improved aspects of \nbehavior in about half of children, ages 5 to 11, in a Phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/6721cbfe24296a3c4a749d3b/images/89f86e34504cbf739c04712ec399b5de05b12f0c7d244904b939da4e5c00062d.png', 'sentiment': 'positive', 'sentiment_prob': 0.5654360055923462}",,,,,,,,,,['positive'],positive,1 NCT02652767,"{'position': 1, 'link': 'https://mitochondrialdiseasenews.com/2017/12/06/gs010-shows-promise-improving-long-term-vision-lhon-gensight-biologics/', 'title': 'GS010 Shows Promise for Improving Long-term Vision in LHON Patients', 'source': 'Mitochondrial Disease News', 'date': 'Dec 6, 2017', 'snippet': ""Learn more about GenSight Biologics' injectable therapy, GS010, which is \nshowing promise in treating patients with Leber Hereditary Optic..."", 'thumbnail': 'https://serpapi.com/searches/6721cc397e1d1f5f594ade31/images/d7e0ad0190e40c682582ae4352870ae636081153706ba888cf7122712dfce394.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6076823472976685}",,,,,,,,,,['positive'],positive,1 NCT04010539,"{'position': 1, 'link': 'https://www.drugtopics.com/view/navigating-women-s-health-utilization-in-a-changing-landscape-amcp-nexus-2024', 'title': ""Navigating Women's Health Utilization in a Changing Landscape | AMCP Nexus 2024"", 'source': 'Drug Topics', 'date': '5 days ago', 'snippet': 'A series of posters presented at AMCP Nexus 2024 focused on 2 key areas: \nthe utilization of medications for preterm birth (PTB) prevention...', 'thumbnail': 'https://serpapi.com/searches/6721cc70e95dbfd3eaa575f6/images/9976821ac111f670bf2485326e61a5b8924ba5d251ed3d7725233817b7dbb2b2.jpeg', 'sentiment': 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2019', 'snippet': 'Maribavir at a dose of at least 400 mg twice daily had efficacy similar to \nthat of valganciclovir for clearing CMV viremia among recipients of \nhematopoietic-...', 'thumbnail': 'https://serpapi.com/searches/6721ccd39e5bd52d11a9bebc/images/538fb088a0a213e20957f4d0a0059ead13051e1a2bbbb476eeecc38f0cdafbc8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7918958067893982}",,,,,,,,,,['neutral'],neutral,1 NCT04648033,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-02041-9', 'title': 'How the histological structure of some lung cancers shaped almost 70 years of radiobiology', 'source': 'Nature', 'date': 'Nov 7, 2022', 'snippet': 'Pivotal research led by Louis Harold Gray in the 1950s suggested that \noxygen plays a vital role during radiotherapy.', 'thumbnail': 'https://serpapi.com/searches/6721ccdd96a3292c5a242246/images/a5e9b3bc4a78048565514823f860c7a54fbf9968fd0ef942a8f3ca64fdcaddf1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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placebo-controlled study in patients with schizophrenia', 'source': 'Nature', 'date': 'Dec 3, 2022', 'snippet': 'KarXT combines xanomeline, an M1/M4 preferring muscarinic agonist with no \ndirect D2 receptor antagonism, with the peripherally restricted...', 'thumbnail': 'https://serpapi.com/searches/6721cd14a3657ab8d46cd736/images/4a1f3e641fde7ef567f3300f4ec574030db843315d62d99fcc7e9a80961585d9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8456377983093262}",,,,,,,,,,['neutral'],neutral,1 NCT02478398,"{'position': 1, 'link': 'https://www.empr.com/home/news/ragwitek-expanded-for-ragweed-pollen-induced-allergic-rhinitis/', 'title': 'Ragwitek Approved for Pediatric Patients With Ragweed Pollen Allergy', 'source': 'Medical Professionals Reference', 'date': 'Apr 19, 2021', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of \nRagwitek (short ragweed pollen allergen extract) to include patients 5 to \n17 years of age.', 'thumbnail': 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obesity paradox in early and advanced HER2 positive breast cancer: pooled analysis of clinical trial data', 'source': 'Nature', 'date': 'Mar 22, 2021', 'snippet': 'While many studies have evaluated the relationship between BMI and breast \ncancer outcomes, it is unclear whether this relationship is...', 'thumbnail': 'https://serpapi.com/searches/6721cd3211db4540a6d92b28/images/bb72c3d329dfc3d71d7aab5e3243625e8a12d81b405d69ea1d8089150875865b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7276222705841064}",,,,,,,,,,['neutral'],neutral,1 NCT03729362,"{'position': 1, 'link': 'https://pompediseasenews.com/news/small-changes-walking-ability-meaningful-advanced-lopd/', 'title': 'Small changes in walking ability can be meaningful in advanced LOPD', 'source': 'Pompe Disease News', 'date': 'May 2, 2024', 'snippet': 'For LOPD patients who are already experiencing difficulty walking, even a \nslowing of decline can be a meaningful improvement, a study says.', 'thumbnail': 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antirheumatic drug. We \nreport the findings of a phase 3 study of monotherapy with...', 'thumbnail': 'https://serpapi.com/searches/6721ce1a49ea55cdb868f3e7/images/8a45ee432aeebe1184348c1236df77825f6d2cf153076035a9134836789e7444.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8552128076553345}",,,,,,,,,,['neutral'],neutral,1 NCT00383188,"{'position': 1, 'link': 'https://www.nature.com/articles/s41417-023-00622-1', 'title': 'P38 kinase in gastrointestinal cancers', 'source': 'Nature', 'date': 'May 29, 2023', 'snippet': 'Dysregulation of p38 pathways, in particular p38γ, are associated with \ncancer development, metastasis, autophagy and tumor microenvironment.', 'thumbnail': 'https://serpapi.com/searches/6721ce5093bb57f4ee1a318f/images/53abb36e20a5af450f00d0bdb0a7ad40429f742971dc26f79ef1da2390323612.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7579556703567505}",,,,,,,,,,['negative'],negative,0 NCT00027300,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa044397', 'title': 'A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Mar 2, 2006', 'snippet': 'Natalizumab reduced the risk of the sustained progression of disability and \nthe rate of clinical relapse in patients with relapsing multiple sclerosis.', 'thumbnail': 'https://serpapi.com/searches/6721ce9cb9ab865d2f7662e4/images/5fc63b51d4c59a43f115a0fa4a3c93b4e372fad80faec521e004bb4b5af6c7ab.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7991609573364258}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/09/29/study-supports-ms-disability-test-score-outcome-measure-trials/', 'title': 'Study Supports MS Disability Test Score as Outcome Measure in Trials', 'source': 'Multiple Sclerosis News Today', 'date': 'Sep 29, 2022', 'snippet': 'The Overall Disability Response Score, which combines three disability \nscores, may help assess the effectiveness of MS treatments in trials.', 'thumbnail': 'https://serpapi.com/searches/6721ce9cb9ab865d2f7662e4/images/5fc63b51d4c59a437c499e5f93abdb6d307f389f729125628476feab042e05cb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7075560688972473}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04928287,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-parkinsons-disease/', 'title': 'Pipeline Moves: advancement prospects jump for Parkinson’s disease stem cell therapy', 'source': 'Clinical Trials Arena', 'date': 'Mar 21, 2023', 'snippet': 'The Clinical Trials Arena team also review assets in asthma, multiple \noncology indications and blood disorder.', 'thumbnail': 'https://serpapi.com/searches/6721cee724296a3c10e59b28/images/a47ffacf3ff47a8f59bd80225df959f8c2adc3c81b91c72fdc024118624a1e70.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7419585585594177}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2023.1139359/full', 'title': 'Mesenchymal stem cell therapy for neurological disorders: The light or the dark side of the force?', 'source': 'Frontiers', 'date': 'Jun 27, 2024', 'snippet': 'Neurological disorders are recognized as major causes of death and \ndisability worldwide. Because of this, they represent one of the largest \npublic health...', 'thumbnail': 'https://serpapi.com/searches/6721cee724296a3c10e59b28/images/a47ffacf3ff47a8f9128ab051d9e46fadc6eaf066c54c9022f1db4084cf7b17b.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5713104009628296}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT03934814,"{'position': 1, 'link': 'https://www.biospectrumasia.com/company-results/48/17177/i-mab-reports-efficacy-of-anti-cd47-monoclonal-ab-on-relapsed-refractory-malignancy.html', 'title': 'I-Mab reports efficacy of Anti-CD47 monoclonal Ab on relapsed/refractory malignancy', 'source': 'BioSpectrum Asia', 'date': 'Nov 25, 2020', 'snippet': 'Initial monotherapy results at Ph 1 clinical trial data demonstrate \ndifferentiated safety and PK profile and efficacy signal of...', 'thumbnail': 'https://serpapi.com/searches/6721d072c117a913ac69f19f/images/69f808d057ce104d3ae8c25ea69662cfbe241c7a33669afac84c34cae5188522.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': ""The US Food and Drug Administration (FDA) has granted fast track status to \nbepirovirsen, GlaxoSmithKline (GSK)'s candidate treatment for chronic \nhepatitis B (..."", 'thumbnail': 'https://serpapi.com/searches/6721d09b7d533ebd2cab35ab/images/111283b63ea856b34c9b5ebe20f65341bc839c63d4379cf05ae40109cd696119.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5451934933662415}",,,,,,,,,,['neutral'],neutral,1 NCT01895361,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1611770', 'title': 'Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease', 'source': 'The New England Journal of Medicine', 'date': 'Dec 3, 2016', 'snippet': 'The up-regulation of P-selectin in endothelial cells and platelets \ncontributes to the cell–cell interactions that are involved in the...', 'thumbnail': 'https://serpapi.com/searches/6721d09c6273fbfd1bbfe82a/images/6316a775f0436442b487d33a5e2c17123176abb0820ddc63e61595f61563acc0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8581187725067139}","{'position': 2, 'link': 'https://sicklecellanemianews.com/news/adakveo-fails-reduce-scd-crises-latest-phase-3-trial-novartis/', 'title': 'Adakveo Fails to Reduce SCD Crises in Latest Phase 3 Trial | Data...', 'source': 'Sickle Cell Disease News', 'date': 'Jan 31, 2023', 'snippet': 'Treatment with Adakveo (crizanlizumab) did not reduce the yearly occurrence \nof painful vaso-occlusive crises (VOCs) leading to a medical visit.', 'thumbnail': 'https://serpapi.com/searches/6721d09c6273fbfd1bbfe82a/images/6316a775f043644214f74a7b297a4f76c176430469044b0b2297fd2dd8f813c6.png', 'sentiment': 'negative', 'sentiment_prob': 0.8098764419555664}","{'position': 3, 'link': 'https://sicklecellanemianews.com/news/fda-approves-adakveo-novartis-scd-pain-crises-treatment-adults-teens/', 'title': 'FDA Approves Novartis’ Adakveo, 1st Treatment for Pain Crises in Teens and Adults with SCD', 'source': 'Sickle Cell Disease News', 'date': 'Nov 18, 2019', 'snippet': 'Adakveo (crizanlizumab), which works to lower the frequency of painful \nvaso-occlusive crises (VOCs) common in sickle cell disease,...', 'thumbnail': 'https://serpapi.com/searches/6721d09c6273fbfd1bbfe82a/images/6316a775f0436442c75797a8f40dd70ca5df84901ac3ee0acfaad02096cc468b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6581161618232727}",,,,,,,,"['neutral', 'negative', 'neutral']",neutral,1 NCT01963052,"{'position': 1, 'link': 'https://dailynews.ascopubs.org/do/antibody-drug-conjugates-treatment-urothelial-carcinoma', 'title': 'Antibody-Drug Conjugates for Treatment of Urothelial Carcinoma', 'source': 'ASCO Daily News', 'date': 'Dec 3, 2020', 'snippet': 'Antibody-drug conjugates (ADCs) provide a sophisticated pharmacologic \nsystem to deliver cytotoxic drugs to cancer cells.', 'thumbnail': 'https://serpapi.com/searches/6721d0b65bb6a2879cc70c5e/images/5e71cf499ea669ef8f034e7b4b644aaa36b9e0d4fae7090807dda1cc57e5645b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7927020192146301}",,,,,,,,,,['neutral'],neutral,1 NCT03505710,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00064-0/abstract', 'title': 'Trastuzumab deruxtecan in patients with metastatic non-small-cell lung cancer (DESTINY-Lung01): primary results of the HER2-overexpressing cohorts from a single-arm, phase 2 trial', 'source': 'The Lancet', 'date': 'Mar 26, 2024', 'snippet': 'DESTINY-Lung01 is a multicentre, open-label, phase 2 study evaluating the \nantitumour activity and safety of trastuzumab deruxtecan, a HER2-directed...', 'thumbnail': 'https://serpapi.com/searches/6721d0f6b9ab865d2f76649f/images/249fc23aa2fab5c315e82f9f1274000f1c75fc38c8711e8a181940827ac0e6e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.882606565952301}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/fda-grants-accelerated-approval-to-t-dxd-in-advanced-her2-solid-tumors', 'title': 'FDA Grants Accelerated Approval to T-DXd in Advanced HER2+ Solid Tumors', 'source': 'Cancer Network', 'date': 'Apr 5, 2024', 'snippet': 'Results from 3 DESTINY trials led to the accelerated approval of \nfam-trastuzumab deruxtecan-nxki for patients with unresectable or...', 'thumbnail': 'https://serpapi.com/searches/6721d0f6b9ab865d2f76649f/images/249fc23aa2fab5c3043a5f4256415b4d53d31ea0ce35d075bff3ca0ef58cd0e5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5295902490615845}","{'position': 3, 'link': 'https://www.oncnursingnews.com/view/adcs-may-change-the-landscape-of-her2-mutant-nsclc', 'title': 'ADCs May Change the Landscape of HER2-Mutant NSCLC', 'source': 'Oncology Nursing News', 'date': '3 days ago', 'snippet': 'Fam-trastuzumab deruxtecan-nxki (Enhertu; T-DXd) is being studied in the \nfrontline setting after data showed that the antibody-drug...', 'thumbnail': 'https://serpapi.com/searches/6721d0f6b9ab865d2f76649f/images/249fc23aa2fab5c369d6f9355dff0a0d5406bb653a606394f05591c7c33dbceb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9045876860618591}","{'position': 4, 'link': 'https://www.oncnursingnews.com/view/fda-grants-accelerated-approval-to-fam-trastuzumab-deruxtecan-nxki-in-her2-solid-tumors', 'title': 'FDA Grants Accelerated Approval to Fam-Trastuzumab Deruxtecan-Nxki in HER2+ Solid Tumors', 'source': 'Oncology Nursing News', 'date': 'Apr 5, 2024', 'snippet': 'The FDA granted accelerated approval to fam-trastuzumab deruxtecan-nxki \n(Enhertu) for patients with unresectable or metastatic HER2-positive...', 'thumbnail': 'https://serpapi.com/searches/6721d0f6b9ab865d2f76649f/images/249fc23aa2fab5c3a9966976c7bd51f977e9dfb95f35388cdb9b9a9c0576b440.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8106153011322021}",,,,,,,"['neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT04719832,"{'position': 1, 'link': 'http://www.msn.com/en-us/health/other/gsk-boasts-win-for-depemokimab-in-asthma-trials/ar-BB1mNpQB?ocid=BingNewsSearch&apiversion=v2&noservercache=1&domshim=1&renderwebcomponents=1&wcseo=1&batchservertelemetry=1&noservertelemetry=1', 'title': 'GSK boasts win for depemokimab in asthma trials', 'source': 'MSN', 'date': '2 days ago', 'snippet': 'GSK has announced positive data from two Phase III trials of its asthma \ncandidate depemokimab. The pharma giant announced the drug met primary \nendpoints in...', 'thumbnail': 'https://serpapi.com/searches/6721d0fc5bb6a2879cc70cb8/images/d67dc3c970cf8dd58224712ecfb613f3aa40a518cc2962232606a88f34f4f61e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8695101737976074}",,,,,,,,,,['positive'],positive,1 NCT04963270,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/gmg-trial-endpoint-met-not-expected-benefit/', 'title': 'Roche subsidiary upset with Phase III gMG trial despite meeting endpoint', 'source': 'Clinical Trials Arena', 'date': 'Mar 22, 2024', 'snippet': 'Enspryng did show statistical significance in gMG but Chugai \nPharmaceuticals said it did not reach the expected level of clinical \nbenefit.', 'thumbnail': 'https://serpapi.com/searches/6721d10159f9117f369c79c8/images/58620e03f7bf532e4f182345715289cd744a331376f42d14370ad3fe60195f9d.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6063151955604553}","{'position': 2, 'link': 'https://myastheniagravisnews.com/news/enspryng-eases-gmg-symptoms-phase-3-trial-below-expectations/', 'title': 'Enspryng eases gMG symptoms in Phase 3 trial, but falls short of hopes', 'source': 'Myasthenia Gravis News', 'date': 'Mar 26, 2024', 'snippet': 'Enspryng (satralizumab), which Chugai Pharmaceutical is testing for \ngeneralized myasthenia gravis (gMG), showed a significant benefit in easing \ndisease...', 'thumbnail': 'https://serpapi.com/searches/6721d10159f9117f369c79c8/images/58620e03f7bf532ebd84173d02bc51b8a50890619f6d10bd34448b9e62cead28.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7288574576377869}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT01631552,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1814213', 'title': 'Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Feb 20, 2019', 'snippet': 'Standard chemotherapy is associated with low response rates and short \nprogression-free survival among patients with pretreated metastatic...', 'thumbnail': 'https://serpapi.com/searches/6721d1049f8bfc043801958e/images/067a7fbb70cd857b3cd3e4908cc33d900a3b9bc3106fba36f5dd6f6269a61a30.png', 'sentiment': 'negative', 'sentiment_prob': 0.6776492595672607}",,,,,,,,,,['negative'],negative,0 NCT02542254,"{'position': 1, 'link': 'https://copdnewstoday.com/news/verona-pharma-rpl554-copd-named-ensifentrine/', 'title': 'Verona Pharma’s Candidate RPL554 for COPD Will Be Named Ensifentrine', 'source': 'COPD News Today', 'date': 'Jan 15, 2019', 'snippet': ""The World Health Organization approved the name ensifentrine for Verona \nPharma's investigational bronchodilator and anti-inflammatory agent,..."", 'thumbnail': 'https://serpapi.com/searches/6721d10fadc33bdfb7d7aa38/images/713e6a7862a1f30d839315250e6cce6f13af33f7d0bfceec21cdac5e259968ed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8575579524040222}",,,,,,,,,,['neutral'],neutral,1 NCT01272219,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1411892', 'title': 'A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management', 'source': 'The New England Journal of Medicine', 'date': 'Jul 2, 2015', 'snippet': 'Obesity is a chronic disease with serious health consequences, but weight \nloss is difficult to maintain through lifestyle intervention alone...', 'thumbnail': 'https://serpapi.com/searches/6721d13d93bb57f524e12d78/images/be3615bdd3e1c12c131301f0fdd2e3eeff000c2e89c17a1840e41f12c85a5d12.png', 'sentiment': 'negative', 'sentiment_prob': 0.4933868646621704}",,,,,,,,,,['negative'],negative,0 NCT01894815,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1612999', 'title': 'Trial of Electrical Direct-Current Therapy versus Escitalopram for Depression', 'source': 'The New England Journal of Medicine', 'date': 'Jun 29, 2017', 'snippet': 'We compared transcranial direct-current stimulation (tDCS) with a selective \nserotonin-reuptake inhibitor for the treatment of depression.', 'thumbnail': 'https://serpapi.com/searches/6721d14175f974f2da18c07d/images/4cc93ae1f14fa2345555ec0a2ce18e3b03a0aec5c39c7bf89222242dc3dfba34.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8650593757629395}",,,,,,,,,,['neutral'],neutral,1 NCT00719797,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1403108', 'title': 'Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 23, 2014', 'snippet': 'A fluoropyrimidine plus irinotecan or oxaliplatin, combined with \nbevacizumab (a monoclonal antibody against vascular endothelial growth...', 'thumbnail': 'https://serpapi.com/searches/6721d1479872174e09996c24/images/0130bb517e09f12d2549d36732c13d8d9a87dff5bdc9a745d7addae2c4322a2e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8642117381095886}","{'position': 2, 'link': 'https://www.nature.com/articles/s41416-020-01089-9', 'title': 'Treatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO', 'source': 'Nature', 'date': 'Oct 7, 2020', 'snippet': 'We performed a pooled analysis of treatments after progression to upfront \nFOLFOXIRI/bev in patients enrolled in two randomised Phase 3 studies (TRIBE \nand TRIBE...', 'thumbnail': 'https://serpapi.com/searches/6721d1479872174e09996c24/images/0130bb517e09f12d5127bf8e81af8cbaba645be0c133412224af52e4e82a76da.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9135832190513611}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00059280,"{'position': 1, 'link': 'https://pompediseasenews.com/lumizyme-alglucosidase-alfa-for-the-treatment-of-pompe-disease/', 'title': 'Lumizyme (Alglucosidase Alfa) in Pompe Disease', 'source': 'Pompe Disease News', 'date': 'Jul 15, 2022', 'snippet': 'Lumizyme (alglucosidase alfa) is an enzyme replacement therapy for Pompe \ndisease. Learn about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/6721d153213c87eb83465fc1/images/333ad874b29cf8f821d320376881c29c6d720da2e700672776060555b8ed5c81.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8790404200553894}",,,,,,,,,,['neutral'],neutral,1 NCT02775903,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/news/advancements-in-aml-and-mds-treatment-with-immune-checkpoint-inhibitors/', 'title': 'Immune Checkpoint Inhibitor Combination Therapy Promising for AML, MDS', 'source': 'Hematology Advisor', 'date': 'Dec 14, 2020', 'snippet': 'Immune checkpoint inhibitors show promise in acute myeloid leukemia and \nmyelodysplastic syndromes.', 'thumbnail': 'https://serpapi.com/searches/6721d1a2740bdba705d91e84/images/ae22a0e422e1e0ac4968811bd7d46f0c82ca4eb0fe25ff3ab9c5cf5c34968960.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.714292585849762}",,,,,,,,,,['positive'],positive,1 NCT02923258,"{'position': 1, 'link': 'https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03541-6', 'title': 'Postoperative radiotherapy with docetaxel versus cisplatin for high-risk oral squamous cell carcinoma: a randomized phase II trial with exploratory analysis of ITGB1 as a potential predictive biomarker', 'source': 'BMC Medicine', 'date': 'Jul 29, 2024', 'snippet': 'This randomized trial directly compared Doc-RT with Cis-RT for high-risk \npostoperative OSCC patients, with comparable efficacy and less toxicity.', 'thumbnail': 'https://serpapi.com/searches/6721d1dc2bab902cc6cb3190/images/e90aa975680e1481807ce22cb23d14cb890a1f667eb82d7e364a4749dbe2038b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.898639440536499}",,,,,,,,,,['neutral'],neutral,1 NCT00604214,"{'position': 1, 'link': 'https://www.nejm.org/doi/abs/10.1056/NEJMoa1202290', 'title': 'Drotrecogin Alfa (Activated) in Adults with Septic Shock', 'source': 'The New England Journal of Medicine', 'date': 'Jun 25, 2018', 'snippet': 'In this randomized, double-blind, placebo-controlled, multicenter trial, we \nassigned 1697 patients with infection, systemic inflammation, and shock who \nwere...', 'thumbnail': 'https://serpapi.com/searches/6721d1e28a7c0938d8968202/images/40a8daaf10813e05bd49847d28a6c5453f723600c9d815179365c7c322d771f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8762322068214417}",,,,,,,,,,['neutral'],neutral,1 NCT02017171,"{'position': 1, 'link': 'https://diatribe.org/diabetes-research/perl-study-trial-use-allopurinol-preserve-kidney-function-type-1-diabetes', 'title': 'PERL Study: A Trial on the Use of Allopurinol to Preserve Kidney Function in Type 1 Diabetes', 'source': 'diaTribe', 'date': 'Feb 5, 2015', 'snippet': 'By Leda Espinoza and Alexander Wolf. Twitter summary: Can a drug for gout \nalso help with #t1d kidney function? 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have excellent potential in \nmanaging several diseases. A vital part of the healthcare system is herbal \nmedicines,...', 'thumbnail': 'https://serpapi.com/searches/6721d33474978395dc84d75a/images/b19e23be87bf41303193cdde0c8511f3c2a70d6f693a5f5142ddca92e783f43b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.9347379803657532}",,,,,,,,,,['positive'],positive,1 NCT04075318,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-024-03101-8', 'title': 'Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial', 'source': 'Nature', 'date': 'Jun 20, 2024', 'snippet': 'This 44-week, randomized, placebo-controlled, double-blind, single-center \nphase 1 study investigated safety, tolerability and immunogenicity of \nUB-312.', 'thumbnail': 'https://serpapi.com/searches/6721d34b24296a3c4a74a2be/images/242091094c9d79c84a6ffa88a8a613f1e2d9c32d6f9cf441f5c041ea0f9a0496.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8822336196899414}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/parkinsons-vaccine-targets-toxic-protein-phase-1-trial/', 'title': 'Parkinson’s vaccine seen to target toxic alpha-synuclein in Phase 1 trial', 'source': ""Parkinson's News Today"", 'date': 'Mar 11, 2024', 'snippet': 'Treatment with UB-312, a vaccine designed to trigger an immune response \nagainst toxic clumps of the alpha-synuclein protein, reduced these \ndamaging...', 'thumbnail': 'https://serpapi.com/searches/6721d34b24296a3c4a74a2be/images/242091094c9d79c88c565de98404c144dc7e1438483cc301eba3a34667a50538.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7458545565605164}","{'position': 3, 'link': 'https://www.neurologylive.com/view/sls-005-performs-better-without-amx0035-nerivio-gains-commercial-coverage-ub-312-reduces--synuclein', 'title': 'SLS-005 Performs Better Without AMX0035, Nerivio Gains Commercial Coverage, UB-312 Reduces α-Synuclein', 'source': 'Neurology live', 'date': 'Mar 23, 2024', 'snippet': 'Neurology News Network for the week ending March 23, 2024. [WATCH TIME: 3 \nminutes]', 'thumbnail': 'https://serpapi.com/searches/6721d34b24296a3c4a74a2be/images/242091094c9d79c830ef2b516b6b44d5423fe2bdc6aca1934f466809f9e93464.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6642199158668518}","{'position': 4, 'link': 'https://parkinsonsnewstoday.com/news/study-therapeutic-parkinsons-vaccine-safely-inhibits-alpha-synuclein-clumps/', 'title': ""Study: Therapeutic Parkinson's vaccine safely inhibits alpha-synuclein clumps"", 'source': ""Parkinson's News Today"", 'date': 'Jun 27, 2024', 'snippet': 'UB-312, a therapeutic vaccine candidate from Vaxxinity, safely led to \nantibodies being produced that could target toxic clumps of the \nalpha-synuclein protein.', 'thumbnail': 'https://serpapi.com/searches/6721d34b24296a3c4a74a2be/images/242091094c9d79c820804c924184127086b283495b74cbcb475db5157bc4c1ac.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4961884617805481}","{'position': 5, 'link': 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some scleroderma patients in a clinical trial.', 'thumbnail': 'https://serpapi.com/searches/6721d3d27ef9fa1a056cc15b/images/049a54451207b011e5f37303c03e71c3c530168b0d2075e8e787a616e2faa972.png', 'sentiment': 'positive', 'sentiment_prob': 0.9240362644195557}","{'position': 3, 'link': 'https://sclerodermanews.com/news/orphan-drug-status-europe-granted-ft011-certa-therapy-ssc/', 'title': 'Certa’s FT011 granted orphan drug status in Europe for SSc', 'source': 'Scleroderma News', 'date': 'Jul 23, 2024', 'snippet': ""The European Medicines Agency granted orphan drug status to FT011, Certa \nTherapeutics' oral treatment candidate for systemic sclerosis..."", 'thumbnail': 'https://serpapi.com/searches/6721d3d27ef9fa1a056cc15b/images/049a54451207b0113712ed16d86d45168506fbf9bdce45e6c82caae8fac6ee03.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9333030581474304}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT01087762,"{'position': 1, 'link': 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trials.', 'thumbnail': 'https://serpapi.com/searches/6721d4924300ce5d3a13efd2/images/124d89f0beba499cba31b31eea0d80a354c9b714c51458fa01753bc423e39199.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6682627201080322}",,,,,,,,,,['neutral'],neutral,1 NCT04019704,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/analyst-comment/zuranolone-mdd-treatment/', 'title': ""Sage Therapeutics/Biogen's Episodic Therapy Zuranolone Could Change MDD Treatment"", 'source': 'Clinical Trials Arena', 'date': 'Jun 24, 2021', 'snippet': 'The pivotal Phase III trial for the new Sage Therapeutics and Biogen \nantidepressant zuranolone has yielded positive results.', 'thumbnail': 'https://serpapi.com/searches/6721d4925416d8e6ac1d14cb/images/29fbae0c14a7e546b5ff14642c59efa0d1a816022a7d344a5198a1cbd5ea45bd.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6174665093421936}",,,,,,,,,,['positive'],positive,1 NCT01032629,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1611925', 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withdrew its application for Linhaliq in the European Union to \ntreat flares in non-cystic fibrosis bronchiectasis linked to P.', 'thumbnail': 'https://serpapi.com/searches/6721d7da72f7160b7410df20/images/55592b5747379f800d0da88cf77433b8ab14b43dc6f05f2cbdfcdbee52db7fc3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6251179575920105}","{'position': 2, 'link': 'https://bronchiectasisnewstoday.com/2017/07/28/non-cystic-fibrosis-bronchiectasis-candidate-therpay-nda-submitted-for-linhaliq-for-p-aeruginosa-infection/', 'title': 'Linhaliq’s NDA Submitted to Treat P. Aeruginosa Infection in NCFBE Patients', 'source': 'Bronchiectasis News Today', 'date': 'Jul 28, 2017', 'snippet': 'Aradigm has submitted a new drug application (NDA) to the US Food and Drug \nAdministration (FDA) for Linhaliq (ciprofloxacin) as a treatment for \nnon-cystic...', 'thumbnail': 'https://serpapi.com/searches/6721d7da72f7160b7410df20/images/55592b5747379f80444f02d6df9462b2e3f710c4f38f4f13cc0ee21188991351.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921363890171051}","{'position': 3, 'link': 'https://bronchiectasisnewstoday.com/2020/12/11/savara-discontinues-development-apulmiq-for-bronchiectasis-ncfb-amid-cost-cutting-measures/', 'title': 'Savara Discontinues Apulmiq Program for NCFB Amid Cost-cutting Measures', 'source': 'Bronchiectasis News Today', 'date': 'Dec 11, 2020', 'snippet': 'Savara Pharmaceuticals has discontinued its clinical program of the inhaled \nantibiotic formulation Apulmiq (ciprofloxacin) for the treatment of \nnon-cystic...', 'thumbnail': 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'title': 'Pembrolizumab plus enzalutamide for metastatic castration-resistant prostate cancer progressing on enzalutamide: cohorts 4 and 5 of the phase 2 KEYNOTE-199 study | Prostate Cancer and Prostatic Diseases', 'source': 'Nature', 'date': 'Aug 12, 2024', 'snippet': 'KEYNOTE-199 (NCT02787005) is a multicohort phase 2 study evaluating \npembrolizumab in patients with metastatic castration-resistant prostate \ncancer (mCRPC).', 'thumbnail': 'https://serpapi.com/searches/6721d8c8ee468296a0062e59/images/ae62b94e7f3ed4af3aed667985df83c814679702e2c853665df717169ef440c9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9012894034385681}",,,,,,,,,,['neutral'],neutral,1 NCT03415854,"{'position': 1, 'link': 'https://dailynews.ascopubs.org/do/pancreatic-tumor-microenvironment-promising-target-complex-challenges', 'title': 'The Pancreatic Tumor Microenvironment Is a Promising Target With Complex Challenges', 'source': 'ASCO Daily News', 'date': 'Jul 10, 2024', 'snippet': 'Key Points: The 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Men and women experience and manage pain differently"", 'source': 'News-Medical', 'date': '1 week ago', 'snippet': 'New study reveals that men rely on opioid-based systems to relieve pain \nwhile women may use unknown pathways, urging the development of...', 'thumbnail': 'https://serpapi.com/searches/6721d9af7f37191077d4d943/images/f39ba2af5109b91038903c9ad6f7c079ccfc547808ef7e273e9701fe30f7da46.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8547735810279846}",,,,,,,,,,['neutral'],neutral,1 NCT01354132,"{'position': 1, 'link': 'https://www.nature.com/articles/s41398-018-0266-8', 'title': 'N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial | Translational Psychiatry', 'source': 'Nature', 'date': 'Oct 12, 2018', 'snippet': 'In this secondary study, we suggest that NAC add-on treatment may be a safe \nand effective way to protect white matter integrity in early psychosis \npatients.', 'thumbnail': 'https://serpapi.com/searches/6721d9cc48e6680fc6679346/images/f3f36012eccf2b1ee39bc3dd062297917b3b1140af05444751fb2832f3edb82a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5601887702941895}",,,,,,,,,,['positive'],positive,1 NCT03945279,"{'position': 1, 'link': 'https://www.als.org/blog/biogen-shares-latest-updates', 'title': 'Biogen Shares Latest Updates on ALS Clinical Trials', 'source': 'The ALS Association', 'date': 'Dec 29, 2020', 'snippet': 'Biogen spoke of its urgent work in targeting genetic forms of ALS caused by \nmutations in some of the most common ALS-associated genes, such as SOD1 and \nC9orf72.', 'thumbnail': 'https://serpapi.com/searches/6721d9e329e6fb3b7acc8536/images/881db3d1d997030a0f839051de1f0d680fa09bbad04565be57800054d409cecd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8600117564201355}",,,,,,,,,,['neutral'],neutral,1 NCT03980522,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/mco2.391', 'title': 'Inflammasome: structure, biological functions, and therapeutic targets - Dai - 2023 - MedComm', 'source': 'Wiley Online Library', 'date': 'Oct 9, 2023', 'snippet': 'Here, we reviewed the activation process and basic structure of \ninflammasomes in both inactive and active states. 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Learn \nmore about its uses, side effects, and clinical testing.', 'thumbnail': 'https://serpapi.com/searches/6721da405f9778874e159e63/images/ac50672a25af663d6e5476c5ccd3495986ef74287f8c6c40b8c8b9f6f66448ec.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9291795492172241}",,,,,,,,,,['neutral'],neutral,1 NCT03649152,"{'position': 1, 'link': 'https://www.nature.com/articles/s41581-021-00427-1', 'title': 'Therapeutic trials in adult FSGS: lessons learned and the road forward', 'source': 'Nature', 'date': 'May 20, 2021', 'snippet': 'Focal segmental glomerulosclerosis (FSGS) is not a specific disease entity \nbut a lesion that primarily targets the podocyte.', 'thumbnail': 'https://serpapi.com/searches/6721da551f3d4b4be5c99cb0/images/6b8f33023c3cde8a40a68d582ea50d1bcd6cf3d92ad4d99917ae4ff29360f767.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8861932754516602}",,,,,,,,,,['neutral'],neutral,1 NCT02323022,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-023-00948-x', 'title': 'Venetoclax plus hypomethylating agents in newly diagnosed acute myeloid leukemia patients with RUNX1::RUNX1T1: a retrospective propensity score matching study | Blood Cancer Journal', 'source': 'Nature', 'date': 'Nov 27, 2023', 'snippet': 'T(8;21)(q22;q22.1)/RUNX1::RUNX1T1 is found in 5–10% of all AML cases and \nresponds well to conventional chemotherapy [1].', 'thumbnail': 'https://serpapi.com/searches/6721da8d460b156b9c59752c/images/e6b11f21e2721e27b16327781d42e5ba7bf2ee087087bf8607c83e81ff7e463f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9110143184661865}",,,,,,,,,,['neutral'],neutral,1 NCT03705390,"{'position': 1, 'link': 'https://alsnewstoday.com/news/ilb-may-slow-als-progression-small-clinical-trial-data-show/', 'title': 'ILB may slow ALS progression, per data from small clinical trial', 'source': 'ALS News Today', 'date': 'Jul 25, 2024', 'snippet': ""Treatment with a high dose of Tikomed's ILB injection therapy appeared to \nsafely slow ALS progression in a clinical trial with 11 patients."", 'thumbnail': 'https://serpapi.com/searches/6721da92a471671c163a328e/images/85f5034e13d1b9207e87c3d32b24faaa6f80384974df6eb0cd9acea1c0bebc7b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5280773043632507}",,,,,,,,,,['neutral'],neutral,1 NCT05086952,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222002839', 'title': 'Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)', 'source': 'ScienceDirect.com', 'date': 'Apr 2, 2022', 'snippet': 'Vericiguat was first drug approved for the treatment of symptomatic \npatients with chronic HF with reduced ejection fraction (HFrEF) to reduce \nthe occurrence of...', 'thumbnail': 'https://serpapi.com/searches/6721daac0e6db341b26c45a6/images/bd4c8d8e63a33fb650fe279fb7d194e85602181ec062e31edf37565bf6f65563.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Spesolimab, a humanized anti–interleukin-36 receptor monoclonal antibody, \nis being studied for the treatment of GPP flares.', 'thumbnail': 'https://serpapi.com/searches/6721dac403775620cb8ecfb2/images/f94aabe6580f9bb50d74d0b139fb313620ced23bbffd979a14775f11c6e9d456.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9019375443458557}","{'position': 2, 'link': 'https://www.empr.com/home/news/spevigo-gets-expanded-approval-for-generalized-pustular-psoriasis/', 'title': 'Spevigo Gets Expanded Approval for Generalized Pustular Psoriasis', 'source': 'Medical Professionals Reference', 'date': 'Mar 19, 2024', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of Spevigo \n(spesolimab-sbzo) to include the treatment of generalized pustular \npsoriasis (GPP)', 'thumbnail': 'https://serpapi.com/searches/6721dac403775620cb8ecfb2/images/f94aabe6580f9bb529d4395cbddf1abe1ab76d197acaeb89796dfc6ad904c7d1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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First-Line Therapy in Patients With Advanced Non–Clear Cell Renal Cell Carcinoma | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Feb 2, 2021', 'snippet': 'PURPOSEProgrammed death 1 (PD-1) pathway inhibitors have not been \nprospectively evaluated in patients with non–clear cell renal cell...', 'thumbnail': 'https://serpapi.com/searches/6721db2fcb33d0118fb64932/images/2dc632601d56fc23dac85d3780756c9ab023acd8549d4a82974e3edb687fc530.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8765980005264282}",,,,,,,,,,['neutral'],neutral,1 NCT02891811,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/news/thalidomide-lenalidomide-new-multiple-myeloma-treatment-risk/', 'title': 'Thalidomide Vs Lenalidomide for Newly Diagnosed Multiple Myeloma', 'source': 'Hematology Advisor', 'date': 'Jul 8, 2022', 'snippet': 'Recent clinical trial results suggested similar efficacy for thalidomide \n(T), compared with lenalidomide (R), in combination with...', 'thumbnail': 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'https://www.ucb.com/clinical-studies/Clinical-studies-index/bimekizumab-UCB4940', 'title': 'Bimekizumab (Bimzelx®)', 'source': 'UCB', 'date': 'Oct 16, 2018', 'snippet': 'Ankylosing Spondylitis, A Multicenter Study to Evaluate the Efficacy and \nSafety of Different Doses of Bimekizumab in Subjects With Active \nAnkylosing...', 'thumbnail': 'https://serpapi.com/searches/6721db86c7d4a1acec2cd8b0/images/0cb5b90cae34affc6d2713d8f4a5d2a85e3301ea80aad1ce5f5475631dfc98aa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8456552028656006}",,,,,,,,,,['neutral'],neutral,1 NCT02949830,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1807838', 'title': 'Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria', 'source': 'The New England Journal of Medicine', 'date': 'Feb 6, 2019', 'snippet': 'Induction of delta aminolevulinic acid synthase 1 (ALAS1) gene expression \nand accumulation of neurotoxic intermediates result in...', 'thumbnail': 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comprehensive review of clinical evidence', 'source': 'Nature', 'date': 'Jul 29, 2020', 'snippet': 'Advanced and recurrent gynecological cancers are associated with poor \nprognosis and lack of effective treatment. The developments of the...', 'thumbnail': 'https://serpapi.com/searches/6721df0bd0d7e3e655d9a8c3/images/51df1b5120ceb1fcd036336501febed40579db850dfe38fa971b0803210ad51e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6648945212364197}",,,,,,,,,,['neutral'],neutral,1 NCT02872103,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/ryzneuta-efbemalenograstim-alfa-evive-fda-biologics-license-application-submission/', 'title': 'Novel Biologic for Chemotherapy-Induced Neutropenia Submitted to FDA', 'source': 'Medical Professionals Reference', 'date': 'Mar 31, 2021', 'snippet': 'The Biologics License Application (BLA) for Ryzneuta™ (efbemalenograstim \nalfa; Evive Biotech) has been submitted to the Food and Drug...', 'thumbnail': 'https://serpapi.com/searches/6721df2cf41044dc44fa9bf7/images/62b9740eed8c78b00e1dbe461a6fa623117fa487cd83fd035e43fac8b2d7938b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9181747436523438}",,,,,,,,,,['neutral'],neutral,1 NCT02494570,"{'position': 1, 'link': 'https://www.onclive.com/view/bui-and-kelly-discuss-the-utility-of-nab-sirolimus-in-advanced-malignant-pecoma', 'title': 'Bui and Kelly Discuss the Utility of Nab-Sirolimus in Advanced Malignant PEComa', 'source': 'OncLive', 'date': 'Jul 18, 2024', 'snippet': 'Drs Bui and Kelly discuss key long-term findings from the AMPECT trial \ninvestigating nab-sirolimus in patients with advanced malignant...', 'thumbnail': 'https://serpapi.com/searches/6721df34ee677f6cfefc62d3/images/4b62b490095e8c129f2038ce1faeb0fcf61fc0f5e834740c26a59c7afac41add.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.952530562877655}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20190103005021/en/Aadi-Bioscience-Receives-Breakthrough-Therapy-Designation-for-TARZIFYX%E2%84%A2%C2%A0-ABI-009-in-PEComa-Indication', 'title': 'Aadi Bioscience Receives Breakthrough Therapy Designation for TARZIFYX™ (ABI-009) in PEComa Indication', 'source': 'Business Wire', 'date': 'Jan 3, 2019', 'snippet': 'Aadi Bioscience Receives Breakthrough Therapy Designation for TARZIFYX \n(ABI-009) in PEComa Indication. Registration study completes...', 'thumbnail': 'https://serpapi.com/searches/6721df34ee677f6cfefc62d3/images/4b62b490095e8c12cb7cd6e0466c532dad8969cb0f628cb2a2ca413ea1cbb31e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6182836294174194}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05523297,"{'position': 1, 'link': 'https://www.cmaj.ca/content/195/22/E773', 'title': 'Nonsurgical management of major hemorrhage', 'source': 'CMAJ', 'date': 'Jun 5, 2023', 'snippet': 'Major hemorrhage is a challenging clinical problem that can occur with \ntraumatic injury, postpartum hemorrhage, major surgery and...', 'thumbnail': 'https://serpapi.com/searches/6721df7ec97e35c23b88a2a5/images/b7167889c244c28289d47e4e37b5be16223d6214af0ad15941aeac1aafecbc24.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6239058375358582}",,,,,,,,,,['negative'],negative,0 NCT02485717,"{'position': 1, 'link': 'https://www.empr.com/home/news/natroba-spinosad-topical-suspension-scabies-infestations/', 'title': 'Natroba Topical Suspension Approved for Scabies Treatment', 'source': 'Medical Professionals Reference', 'date': 'Apr 29, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Natroba TM (spinosad) \ntopical suspension for the treatment of scabies infestations in patients 4 \nyears of...', 'thumbnail': 'https://serpapi.com/searches/6721dfbe6901215799fd0cc9/images/eba889911aefc7955b4cd8dfb482660fc014e31e13588f3dd20597759d97617a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8773550987243652}",,,,,,,,,,['neutral'],neutral,1 NCT01642212,"{'position': 1, 'link': 'https://www.empr.com/home/news/eohilia-an-oral-therapy-for-eosinophilic-esophagitis-gets-fda-approval/', 'title': 'Eohilia, an Oral Therapy for Eosinophilic Esophagitis, Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Feb 12, 2024', 'snippet': 'The approval of Eohilia was based on data from 2 double-blind, \nparallel-group, placebo-controlled 12-week phase 3 trials.', 'thumbnail': 'https://serpapi.com/searches/6721e01b163bdf528ce1824a/images/d8be4f3472a7aa5dc91492d75df7ef5ad05666f6f7218c5509b5fa548238923e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6682627201080322}",,,,,,,,,,['neutral'],neutral,1 NCT03121716,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/lary.30971', 'title': 'Immune Checkpoint Inhibitors Serve as the First-Line Treatment for Advanced Head and Neck Cancer', 'source': 'Wiley Online Library', 'date': 'Aug 23, 2023', 'snippet': 'Objectives Immune checkpoint inhibitor (ICI) therapy has demonstrated \nsubstantial benefits for certain patients. We try to evaluate the...', 'thumbnail': 'https://serpapi.com/searches/6721e06d3d629b098cc1c7e0/images/ee24efd1c9d29fdd7adc6e286edc492477c939b8c216a208d6c05885f127eff0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7475776672363281}",,,,,,,,,,['neutral'],neutral,1 NCT03054363,"{'position': 1, 'link': 'https://www.onclive.com/view/tucatinib-letrozole-palbociclib-combination-demonstrates-meaningful-efficacy-in-hr-her2-mbc', 'title': 'Tucatinib/Letrozole/Palbociclib Combination Demonstrates Meaningful Efficacy in HR+/HER2+ mBC', 'source': 'OncLive', 'date': 'Aug 16, 2023', 'snippet': 'Treatment with the all-oral triplet of tucatinib, letrozole, and \npalbociclib yielded clinically meaningful efficacy results and had an...', 'thumbnail': 'https://serpapi.com/searches/6721e06f2c83d57e41df460d/images/435efa31909e863376b945f13e4d60164012265ba85aee553b2c2a9af28e210b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5219252705574036}",,,,,,,,,,['positive'],positive,1 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to activate immune effectors against \ntumor antigens, utilize a number of different platforms for...', 'thumbnail': 'https://serpapi.com/searches/6721e12ddb3ac9d23d14b124/images/4407d5f80a365a1a4a67c2ff1562f4af47d8b5091e911554fb4fb3769565ac13.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9000220894813538}",,,,,,,,,,['neutral'],neutral,1 NCT02149225,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-51315-8', 'title': 'A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine', 'source': 'Nature', 'date': 'Aug 11, 2024', 'snippet': 'Current treatment outcome of patients with glioblastoma (GBM) remains poor. \nFollowing standard therapy, recurrence is universal with limited...', 'thumbnail': 'https://serpapi.com/searches/6721e139cc48791e95263fc6/images/ddc203382dadf18f87dfb176bc5d24a551a58474f3d799e5207b34695ab3171c.png', 'sentiment': 'negative', 'sentiment_prob': 0.5740231275558472}",,,,,,,,,,['negative'],negative,0 NCT04504279,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/probiotic-skin-therapy-improves-eczema-children-nih-study-suggests', 'title': 'Probiotic skin therapy improves eczema in children, NIH study suggests', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Sep 9, 2020', 'snippet': 'An experimental treatment for eczema that aims to modify the skin \nmicrobiome safely reduced disease severity and increased quality of life \nfor children as...', 'thumbnail': 'https://serpapi.com/searches/6721e1619e5bd52d11a9cf4c/images/12f38e4b488d7b9d7470527c5f8f9e7cb4242ab7d36af64a96bf8437a851ed71.png', 'sentiment': 'positive', 'sentiment_prob': 0.6485627293586731}",,,,,,,,,,['positive'],positive,1 NCT03589469,"{'position': 1, 'link': 'https://www.oncnursingnews.com/view/edema-and-effusion-with-loncastuximab-tesirine-is-manageable-in-patients-with-relapsed-refractory-dlbcl', 'title': 'Edema and Effusion With Loncastuximab Tesirine Is Manageable in Patients With Relapsed/Refractory DLBCL', 'source': 'Oncology Nursing News', 'date': 'May 29, 2022', 'snippet': 'Nurse investigators characterized the onset and management of edema and \neffusion with loncastuximab tesirine in the pivotal LOTIS-2 trial.', 'thumbnail': 'https://serpapi.com/searches/6721e1962a7727b885787b52/images/3757117cd1ccb1b77fc9fbcc458bf015f5548190f959d91e0ad3b624ca6a91fb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9146631360054016}","{'position': 2, 'link': 'https://lymphomanewstoday.com/2019/09/13/adc-therapeutics-freenone-partner-to-identify-dlbcl-patients-likely-to-benefit-adct-402/', 'title': 'Identifying DLBCL Patients Most Likely to Benefit from ADCT-402 Goal of Partnership', 'source': 'Lymphoma News Today', 'date': 'Sep 13, 2019', 'snippet': 'ADCT-402, an antibody-drug conjugate targeting a protein common to blood \ncancers, is in a pivotal Phase 2 trial enrolling people with...', 'thumbnail': 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'https://www.nature.com/articles/s41366-024-01473-y', 'title': 'What is the pipeline for future medications for obesity? - International Journal of Obesity', 'source': 'Nature', 'date': 'Feb 1, 2024', 'snippet': 'In this review, we present the efficacy and safety data for the pipeline of \nobesity pharmacotherapies with a focus on entero-pancreatic hormone-based...', 'thumbnail': 'https://serpapi.com/searches/6721e1b6e1c27656633a5f9c/images/32d80dc0aa5516ee6283ab40de791a6aa9ec03091cf58d2a8b7be05d63d6a9d3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9023082256317139}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/analyst-comment/easd-2024-mazdutide-cardiometabolic-function-overweight-patients/', 'title': 'EASD 2024: Mazdutide improves cardiometabolic function in overweight patients', 'source': 'Clinical Trials Arena', 'date': '1 month ago', 'snippet': 'At EASD 2024, Eli Lilly and Co announced the most recent trial results for \nmazdutide, its dual GLP-1R/ (GCGR) agonist.', 'thumbnail': 'https://serpapi.com/searches/6721e1b6e1c27656633a5f9c/images/32d80dc0aa5516ee7c4700825cbdbb017a4bb4530950ceffdad56c7000f215b1.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8030769228935242}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04089553,"{'position': 1, 'link': 'https://www.onclive.com/view/azd4635-plus-durvalumab-or-oleclumab-has-minimal-clinical-activity-in-mcrpc', 'title': 'AZD4635 Plus Durvalumab or Oleclumab Has Minimal Clinical Activity in mCRPC', 'source': 'OncLive', 'date': 'Sep 26, 2022', 'snippet': 'The addition of AZD4635 to durvalumab or oleclumab did not elicit \nsignificant responses in heavily pretreated patients with metastatic...', 'thumbnail': 'https://serpapi.com/searches/6721e1b96ad3c98a9f93dc22/images/1f3537b1a6c062fd4422bf24f633408b1a08fb74675d282e2647b9a4df06642c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5966070294380188}",,,,,,,,,,['neutral'],neutral,1 NCT05224531,"{'position': 1, 'link': 'https://pulmonaryhypertensionnews.com/news/cereno-pah-investigational-candidate-cs1-granted-compassionate-use/', 'title': ""Cereno's PAH investigational candidate CS1 granted compassionate use"", 'source': 'Pulmonary Hypertension News', 'date': 'Feb 2, 2024', 'snippet': ""The FDA has approved the use of Cereno Scientific's CS1 in an extension of \nthe ongoing Phase 2 trial testing the therapy in people with PAH."", 'thumbnail': 'https://serpapi.com/searches/6721e1d6f3cbfaeee3c380bc/images/a82db1cc5914ee1a7686f0e47f65d6cc498e884629ebe64c5602ae403ee89177.png', 'sentiment': 'neutral', 'sentiment_prob': 0.682741641998291}",,,,,,,,,,['neutral'],neutral,1 NCT03452228,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02222-w', 'title': 'Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial', 'source': 'Nature', 'date': 'Mar 6, 2023', 'snippet': 'This phase 2 trial (NCT03452228) evaluated evinacumab (angiopoietin-like 3 \ninhibitor) in three cohorts of patients with sHTG.', 'thumbnail': 'https://serpapi.com/searches/6721e1e8d910390616b32315/images/f95ec0bd04b62fa6e3a7ec954e69feeacb6823aab712290ee607e01368f7064b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8509107232093811}",,,,,,,,,,['neutral'],neutral,1 NCT02770807,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20240815940181/en/Quince-Therapeutics-Announces-The-Lancet-Neurology-Publication-of-Phase-3-ATTeST-Clinical-Trial-Data-Evaluating-EryDex-for-the-Treatment-of-Ataxia-Telangiectasia-A-T', 'title': 'Quince Therapeutics Announces The Lancet Neurology Publication of Phase 3 ATTeST Clinical Trial Data Evaluating EryDex for the Treatment of Ataxia-Telangiectasia (A-T)', 'source': 'Business Wire', 'date': 'Aug 15, 2024', 'snippet': 'The results of this study demonstrate the encouraging efficacy and safety \nprofile of our lead asset, EryDex, for the treatment of patients with AT.', 'thumbnail': 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'sentiment': 'neutral', 'sentiment_prob': 0.9124823212623596}",,,,,,,,,,['neutral'],neutral,1 NCT00296322,"{'position': 1, 'link': 'https://www.nature.com/articles/bjc201386', 'title': 'Adjuvant chemotherapy for gastric cancer: a randomised phase 3 trial of mitomycin-C plus either short-term doxifluridine or long-term doxifluridine plus cisplatin after curative D2 gastrectomy (AMC0201)', 'source': 'Nature', 'date': 'Feb 28, 2013', 'snippet': 'This phase 3 study evaluated the efficacy of new adjuvant chemotherapy \n(MFP), which intensified the mitomycin-C (MMC) plus short-term \ndoxifluridine (Mf) for...', 'thumbnail': 'https://serpapi.com/searches/6721e29dd11a89f6ae7e83e8/images/444670d8015fc2f9fcb1c157cd9394f29ee3f8ec7f6c02b3815e9999e35721b3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8950435519218445}",,,,,,,,,,['neutral'],neutral,1 NCT00543543,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1405044', 'title': 'A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women', 'source': 'The New England Journal of Medicine', 'date': 'Feb 19, 2015', 'snippet': 'The investigational 9-valent viruslike particle vaccine against human \npapillomavirus (HPV) includes the HPV types in the quadrivalent HPV...', 'thumbnail': 'https://serpapi.com/searches/6721e2a31adaf494051cbdc0/images/b44bda8c0fc6a499ca45492e62a79b9271e7eccb43ccb917521e00052037dc5c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8380662202835083}",,,,,,,,,,['neutral'],neutral,1 NCT03226678,"{'position': 1, 'link': 'https://coldagglutininnews.com/news/experimental-cad-therapy-pegcetacoplan-halted-developers/', 'title': 'Experimental CAD therapy pegcetacoplan halted by developers', 'source': 'Cold Agglutinin Disease News', 'date': 'Mar 7, 2024', 'snippet': 'Apellis Pharmaceuticals and Swedish Orphan Biovitrum (Sobi) have stopped \nthe clinical development of the experimental therapy pegcetacoplan for cold \nagglutinin...', 'thumbnail': 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'https://www.globenewswire.com/news-release/2023/09/07/2739412/0/en/Sorrento-Therapeutics-Announces-Positive-Phase-2a-Clinical-Trial-Results-for-Resiniferatoxin-RTX-for-the-Treatment-of-Knee-Pain-in-Moderate-to-Severe-Osteoarthritis-of-the-Knee-OAK.html', 'title': 'Sorrento Therapeutics Announces Positive Phase 2a Clinical Trial Results for Resiniferatoxin (RTX) for the Treatment of Knee Pain in Moderate to Severe Osteoarthritis of the Knee (OAK) Patients', 'source': 'GlobeNewswire', 'date': 'Sep 7, 2023', 'snippet': 'All study objectives were met, demonstrating safety across dose groups and \nconfirming efficacy and durability at the selected doses against...', 'thumbnail': 'https://serpapi.com/searches/6721e3dc20e6eb9381df0055/images/2e64b1ce03ea5a859981b2a63fc9251b6c590cf62458d0de12604dbd1f88df4b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6346057057380676}",,,,,,,,,,['neutral'],neutral,1 NCT03511664,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2107322', 'title': 'Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 23, 2021', 'snippet': 'Lutetium-177 ( 177 Lu)–PSMA-617 is a radioligand therapy that delivers \nbeta-particle radiation to PSMA-expressing cells and the surrounding \nmicroenvironment.', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f2926f0902a179bac1a73756d6ad67847c31eac1911f2de819.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8383318781852722}","{'position': 2, 'link': 'http://www.urotoday.com/conference-highlights/asco-2021/asco-2021-prostate-cancer/130016-asco-2021-vision.html', 'title': 'ASCO 2021: Phase III Study of Lutetium-177-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer (VISION)', 'source': 'UroToday', 'date': 'Jun 6, 2021', 'snippet': 'ASCO plenary VISION study, VISION Michael Morris, Phase III VISION study \nVISION 177Lu-PSMA-617, VISION targeted radioligand therapy in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f2f263d2b04e2bf76c08620f13e3f57e0b4cca66cefb65d468.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9214782118797302}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/fda-approves-177lu-psma-617-for-pretreated-psma-metastatic-castration-resistant-prostate-cancer', 'title': 'FDA Approves 177Lu-PSMA-617 for Pretreated PSMA+ Metastatic Castration-Resistant Prostate Cancer', 'source': 'Cancer Network', 'date': 'Mar 23, 2022', 'snippet': 'Based on data from the phase 3 VISION trial, 177Lu-PSMA-617 may now be used \nto treat patients who were previously treated with androgen...', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f2d0eac48b140852044f338dfdd236531398fd5889919004a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9058717489242554}","{'position': 4, 'link': 'https://www.targetedonc.com/view/adding-lupsma-to-standard-treatment-extends-os-delays-disease-progression-in-mcrpc', 'title': 'Adding LuPSMA to Standard Treatment Extends OS, Delays Disease Progression in mCRPC', 'source': 'Targeted Oncology', 'date': 'Aug 15, 2021', 'snippet': 'Adding the targeted radioligand LuPSMA to standard of care therapy for \npatients with metastatic castration resistant prostate cancer after...', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f23afdc938132dfeb9d7aab3f6169a157dd86dd64d4e20a0cd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6937063932418823}","{'position': 5, 'link': 'https://dailynews.ascopubs.org/do/evaluating-current-role-psma-pet-utility-availability-and-challenges', 'title': 'Evaluating the Current Role of PSMA PET: Utility, Availability, and Challenges', 'source': 'ASCO Daily News', 'date': 'Mar 2, 2022', 'snippet': 'Although the U.S. Food and Drug Administration (FDA) approved a \nprostate-specific membrane antigen (PSMA) imaging agent in 1996...', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f24f7385bdb07c36c904338962250bd4f55d710fa33deeff60.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.930873453617096}","{'position': 6, 'link': 'https://www.cancernetwork.com/view/fda-expands-indication-for-illuccix-for-psma-radioligand-selection-in-prostate-cancer', 'title': 'FDA Expands Indication for Illuccix for PSMA Radioligand Selection in Prostate Cancer', 'source': 'Cancer Network', 'date': 'Mar 16, 2023', 'snippet': 'Use of a kit that prepares for gallium Ga 68 gozetotide injection in the \nphase 3 VISION study affirms its ability to identify patients who...', 'thumbnail': 'https://serpapi.com/searches/6721e3de9f8bfc043801a47b/images/1c644207db6743f289b71c2ee45a8ddbe4c22db7c53b55f6d752796d8721ec13.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8985714912414551}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 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'snippet': 'Hypomethylating agents (HMAs) are the standard of care for patients with \nhigher-risk myelodysplastic neoplasms (HR-MDS) and, in combination...', 'thumbnail': 'https://serpapi.com/searches/6721e43b90adce9b27b70ecf/images/c5104f5ee502ce2724a124174e9bc0a89440d995b53cb17d6421ab7b0e8cbce0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7940686345100403}",,,,,,,,,,['neutral'],neutral,1 NCT04875962,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-023-00552-7', 'title': 'In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson’s disease', 'source': 'Nature', 'date': 'Jul 17, 2023', 'snippet': 'Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant small \nmolecule ASYN misfolding inhibitor in clinical development as a \ndisease-modifying...', 'thumbnail': 'https://serpapi.com/searches/6721e492b9458d9fbfbdb767/images/b658b42c365f55c1974eb90d751a86843baaafeee121ecb47f728a8d15026de6.png', 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drug succeeds in Phase III, but data yet to be released', 'source': 'Clinical Trials Arena', 'date': '1 month ago', 'snippet': ""UCB and Biogen's drug dapirolizumab pegol has met the primary endpoint of \nimprovement in disease activity in lupus patients."", 'thumbnail': 'https://serpapi.com/searches/6721e4b78b84c46fd6164220/images/c56b2e21293837ba74cb0dc13008b209b8f6ab98bd4b37f5621db0b7b801c1e1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5893003344535828}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04785612,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2116154', 'title': 'Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study', 'source': 'The New England Journal of Medicine', 'date': 'Jun 22, 2022', 'snippet': 'RSVpreF vaccine was effective against symptomatic RSV infection and viral \nshedding. No evident safety concerns were identified.', 'thumbnail': 'https://serpapi.com/searches/6721e4b9690bb92396ca29d2/images/17d3cfc01286da2e1c82fdbe373267bb6c3d77943ac2718234ec481fe06699b3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7741875052452087}",,,,,,,,,,['neutral'],neutral,1 NCT00333840,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1609324', 'title': 'Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Mar 9, 2017', 'snippet': 'Imatinib, a selective BCR-ABL1 kinase inhibitor, improved the prognosis for \npatients with chronic myeloid leukemia (CML).', 'thumbnail': 'https://serpapi.com/searches/6721e4d724296a3c10e5ad70/images/c92474518807fb748645c3afcf192204c993df6e4f4afc41ecead025c42d7b81.png', 'sentiment': 'positive', 'sentiment_prob': 0.6723223924636841}",,,,,,,,,,['positive'],positive,1 NCT03633617,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2205982', 'title': 'Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 21, 2022', 'snippet': 'We conducted a three-part, phase 3 trial in which patients 12 years of age \nor older underwent randomization in a 1:1 ratio to receive...', 'thumbnail': 'https://serpapi.com/searches/6721e4f7e8735a1451f2d1eb/images/d6c264e4b791da274f987ea582be99178d576efe3bd6949db4f43fb91f8d0b0b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.871994137763977}",,,,,,,,,,['neutral'],neutral,1 NCT02186873,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2018/01/22/simponi-aria-for-treating-ankylosing-spondylitis-efficient-safe-phase-3-trial-shows/', 'title': 'Ankylosing Spondylitis Therapy Simponi Aria Is Safe, Efficient, Trial Shows', 'source': 'Ankylosing Spondylitis News', 'date': 'Jan 22, 2018', 'snippet': 'Read about the results of a Phase 3 clinical trial showing that intravenous \ninfusion of Simponi Aria significantly improved ankylosing...', 'thumbnail': 'https://serpapi.com/searches/6721e51b17b10e7c5036f801/images/ac9c7d5744a025154dd41427a0eb88a5534f00050442073740a41ee52237e05e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6997513771057129}",,,,,,,,,,['positive'],positive,1 NCT04001517,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-32944-3', 'title': 'Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration', 'source': 'Nature', 'date': 'Sep 21, 2022', 'snippet': 'The endosome-associated GTPase Rab5 is a central player in the molecular \nmechanisms leading to degeneration of basal forebrain cholinergic...', 'thumbnail': 'https://serpapi.com/searches/6721e52d2da98308910ad670/images/a70f16473666115340d4ac49b17f04649d6b169272b8f06559b1ea3d6e48f938.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8358699679374695}",,,,,,,,,,['neutral'],neutral,1 NCT01564784,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1509277', 'title': 'Inotuzumab Ozogamicin versus Standard Therapy for Acute Lymphoblastic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Jun 12, 2016', 'snippet': 'The rate of complete remission was higher with inotuzumab ozogamicin than \nwith standard therapy, and a higher percentage of patients in the \ninotuzumab...', 'thumbnail': 'https://serpapi.com/searches/6721e53af963e7b1d30971b3/images/5a3ec64994b0a327d88106d363311bb9405d246bc2998113bf624bf4c53a22eb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7057051062583923}",,,,,,,,,,['neutral'],neutral,1 NCT04761822,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-begins-study-allergic-reactions-moderna-pfizer-biontech-covid-19-vaccines', 'title': 'NIH begins study of allergic reactions to Moderna, Pfizer-BioNTech COVID-19 vaccines', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Apr 7, 2021', 'snippet': 'Adults interested in participating in this trial should visit \nClinicalTrials.gov and search under study identifier NCT04761822 for \nstudy...', 'thumbnail': 'https://serpapi.com/searches/6721e55a7ac73169f8527e6b/images/d3eb61f8c9eb2c413ae9c189e31fcd02a1dd193d013aab4aae3ad4db36155a21.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8997783064842224}",,,,,,,,,,['neutral'],neutral,1 NCT02201849,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/vumerity-diroximel-fumarate/', 'title': 'Vumerity (diroximel fumarate) in MS | Uses, side effects, and more...', 'source': 'Multiple Sclerosis News Today', 'date': 'May 3, 2022', 'snippet': 'Vumerity (diroximel fumarate) is an oral treatment for people with \nrelapsing forms of MS. Learn about its uses, indications, and side...', 'thumbnail': 'https://serpapi.com/searches/6721e57abb55ff271c7d1be5/images/d7110ef3d7b42fb848e2704fbfb98325be6368aa6c6517086eba0c89ef7f340a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9147942066192627}",,,,,,,,,,['neutral'],neutral,1 NCT02602509,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-018-31590-4', 'title': 'Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model', 'source': 'Nature', 'date': 'Sep 10, 2018', 'snippet': 'COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) \nthrough a number of pathways including efflux pump inhibition...', 'thumbnail': 'https://serpapi.com/searches/6721e58de1c27656915c9a93/images/fe36a535187dce2f75b097b951c4729a5f1daae3d614ddaabcf913afbdf67087.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8828105330467224}",,,,,,,,,,['neutral'],neutral,1 NCT02700529,"{'position': 1, 'link': 'https://lungdiseasenews.com/2018/01/19/ubenimex-development-treat-pulmonary-arterial-hypertension-ends/', 'title': 'Ubenimex Development to Treat Pulmonary Arterial Hypertension Ends', 'source': 'Lung Disease News', 'date': 'Jan 19, 2018', 'snippet': ""Eiger BioPharmaceuticals' ubenimex failed to show improvement in pulmonary \nvascular resistance or exercise capacity in the Phase 2 LIBERTY..."", 'thumbnail': 'https://serpapi.com/searches/6721e59b7ef9fa1a316667f1/images/d661cf8618f491fbc5840ee3fb17d4743686f4f30467c194b72d6cadb24101f2.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6212904453277588}",,,,,,,,,,['negative'],negative,0 NCT02395666,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/norgine-bv-submits-marketing-authorisation-application-via-project-orbis-for-eflornithine-difluoromethylornithine-dfmo-in-high-risk-neuroblastoma-302116815.html', 'title': 'Norgine B.V. submits Marketing Authorisation Application via Project Orbis for eflornithine (difluoromethylornithine [DFMO]) in high-risk neuroblastoma', 'source': 'PR Newswire', 'date': 'Apr 15, 2024', 'snippet': 'PRNewswire/ -- Norgine B.V. today announced its first marketing \nauthorisation application submissions on 10 April 2024, seeking approval \nfor...', 'thumbnail': 'https://serpapi.com/searches/6721e5c3358539d6676d5e07/images/e908c2fafd08aefc1f351d44458c026334a5c51c513b1756c7f0fd3258c796cf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9145628213882446}","{'position': 2, 'link': 'https://www.contemporarypediatrics.com/view/fda-approves-eflornithine-for-pediatric-patients-with-high-risk-neuroblastoma', 'title': 'FDA approves eflornithine for pediatric patients with high-risk neuroblastoma', 'source': 'Contemporary Pediatrics', 'date': 'Dec 14, 2023', 'snippet': 'The FDA has approved eflornithine (IWILFIN; US WorldMeds) 192 mg tablets to \nreduce the risk of relapse in adult and pediatric patients with high-risk...', 'thumbnail': 'https://serpapi.com/searches/6721e5c3358539d6676d5e07/images/e908c2fafd08aefc28c893953cf06da5a8f0fff1ec8df3d8453a0bb92ca66895.png', 'sentiment': 'neutral', 'sentiment_prob': 0.815450131893158}","{'position': 3, 'link': 'https://www.cancerhealth.com/blog/fda-approves-iwilfin-highrisk-neuroblastoma', 'title': 'FDA Approves Iwilfin for High-Risk Neuroblastoma', 'source': 'Cancer Health', 'date': 'Dec 18, 2023', 'snippet': 'The Food and Drug Administration approved eflornithine (Iwilfin, USWM, LLC) \nto reduce the risk of relapse in adult and pediatric patients with \nhigh-risk...', 'thumbnail': 'https://serpapi.com/searches/6721e5c3358539d6676d5e07/images/e908c2fafd08aefcf544c78378c6f2e5227256623f8212630a68b90da379350f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8126423358917236}","{'position': 4, 'link': 'https://www.thepharmaletter.com/pharmaceutical/us-worldmeds-nabs-fda-approval-for-eflornithine-in-neuroblastoma', 'title': 'US WorldMeds nabs FDA approval for eflornithine in neuroblastoma', 'source': 'The Pharma Letter', 'date': 'Dec 15, 2023', 'snippet': 'More on this story... FDA vote bodes well for US WorldMeds. Pharmaceutical \n· FDA vote bodes well for US WorldMeds. 5 October 2023.', 'thumbnail': 'https://serpapi.com/searches/6721e5c3358539d6676d5e07/images/e908c2fafd08aefcbfa10f48f56b837521fb2a5cbce5cf7a6d52d68eec0a145b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5894373059272766}","{'position': 5, 'link': 'https://www.empr.com/home/news/iwilfin-an-oral-maintenance-therapy-for-high-risk-neuroblastoma-gets-fda-approval/', 'title': 'Iwilfin, an Oral Maintenance Therapy for High-Risk Neuroblastoma, Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Dec 14, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Iwilfin™ (eflornithine) \nto reduce the risk of relapse in adult and pediatric patients...', 'thumbnail': 'https://serpapi.com/searches/6721e5c3358539d6676d5e07/images/e908c2fafd08aefc3bee780971788ac2e7e92898bcc403f9481f7d80591ef3cf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6843135356903076}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01967173,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1905560', 'title': 'Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma', 'source': 'The New England Journal of Medicine', 'date': 'Sep 25, 2019', 'snippet': 'Data indicate that patients with inadequately controlled asthma benefit \nmore from addition of a long-acting beta-agonist (LABA) than from \nincreased...', 'thumbnail': 'https://serpapi.com/searches/6721e60913e5d81f5e774890/images/742202b342fd998748127f4d40c455041e8cc123bddcf3f3dc115a2766c45e6e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.560771107673645}",,,,,,,,,,['neutral'],neutral,1 NCT04402060,"{'position': 1, 'link': 'https://www.nature.com/articles/s41577-021-00665-1', 'title': 'The state of complement in COVID-19', 'source': 'Nature', 'date': 'Dec 15, 2021', 'snippet': 'Hyperactivation of the complement and coagulation systems is recognized as \npart of the clinical syndrome of COVID-19.', 'thumbnail': 'https://serpapi.com/searches/6721e68990adce9b27b71078/images/3bf00b819ba8452d41a1f6b593955e0e680942bd195a35514c9beb056d33f7ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.706369161605835}",,,,,,,,,,['neutral'],neutral,1 NCT04336410,"{'position': 1, 'link': 'https://www.technologynetworks.com/biopharma/blog/13-covid-19-vaccines-are-in-human-clinical-trials-what-are-they-336738', 'title': '13 COVID-19 Vaccines Are in Human Clinical Trials – What Are They?', 'source': 'Technology Networks', 'date': 'Jun 29, 2020', 'snippet': 'The World Health Organization recognizes that, as of June 22, there are \nover 140 vaccines against COVID-19 in various stages of development.', 'thumbnail': 'https://serpapi.com/searches/6721e6901397bae53c6be0ad/images/17f3641db732cac6c128c03b1dd6faf8686f4bc70004e23827791455c502880d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9003502130508423}",,,,,,,,,,['neutral'],neutral,1 NCT01626495,"{'position': 1, 'link': 'https://www.nature.com/articles/s41417-021-00418-1', 'title': 'Use of CAR T-cell for acute lymphoblastic leukemia (ALL) treatment: a review study', 'source': 'Nature', 'date': 'Jan 5, 2022', 'snippet': 'In this review different generations, challenges, and clinical studies \nrelated to chimeric antigen receptor (CAR) T-cells for ALL treatment are \ndiscussed.', 'thumbnail': 'https://serpapi.com/searches/6721e6929109867ed4fff633/images/3b0a5909b15fab98be423f16ebc9a8523d90d915ef041b86e8c6e9557d749b8a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8729193210601807}",,,,,,,,,,['neutral'],neutral,1 NCT02609828,"{'position': 1, 'link': 'https://www.oncologynurseadvisor.com/news/tanezumab-cancerp-ain-no-longer-development/', 'title': 'Tanezumab Can Reduce Cancer Pain but Is No Longer Under Development', 'source': 'Oncology Nurse Advisor', 'date': 'Jul 17, 2023', 'snippet': 'Results of a phase 3 trial suggest that tanezumab can reduce pain in cancer \npatients, but the drug is no longer under development.', 'thumbnail': 'https://serpapi.com/searches/6721e6a32fab6260abe24136/images/90d170105aaef22dc0d17d9f9c1831f2c10772105241a7bc15c99fd8df069f80.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5751845836639404}",,,,,,,,,,['neutral'],neutral,1 NCT02468193,"{'position': 1, 'link': 'https://cushingsdiseasenews.com/news/isturisa-effective-in-treating-cushings-syndrome-other-than-cushings-disease-phase-2-trial-shows/', 'title': 'Isturisa Effective in Treating Cushing’s Syndrome Other Than...', 'source': ""Cushing's Disease News"", 'date': 'Jul 1, 2020', 'snippet': ""Combined with results from previous trials in Cushing's disease, the data \nshows Isturisa is a safe and effective therapy option."", 'thumbnail': 'https://serpapi.com/searches/6721e6acbe80137f75540209/images/3f4a2e7e1a1000241a5d1adfa6197b8eeae1eadd9d5195d117d6a4ece57e6933.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.63901287317276}",,,,,,,,,,['neutral'],neutral,1 NCT03752905,"{'position': 1, 'link': 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\n(ustekinumab-auub), an interchangeable biosimilar to Stelara (ustekinumab).', 'thumbnail': 'https://serpapi.com/searches/6721e6b7740bdba705d92ee1/images/e86761b106a048a16e1a665143716388a466347b8e606c1b9e125f7157e5c6a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6312623620033264}",,,,,,,,,,['neutral'],neutral,1 NCT04773600,"{'position': 1, 'link': 'https://www.medcentral.com/dermatology/fda-approves-non-steroidal-roflumilast-cream-for-atopic-dermatitis', 'title': 'FDA Approves Non-Steroidal Roflumilast Cream for Atopic Dermatitis', 'source': 'MedCentral', 'date': 'Jul 9, 2024', 'snippet': 'The US Food and Drug Administration (FDA) approved Zoryve (roflumilast \n0.15% cream, Arcutis Biotherapeutics) for adults and children aged 6 years \nand older...', 'thumbnail': 'https://serpapi.com/searches/6721e718d72128f26f3271ce/images/7dcf3534e713a1b869163d8ac6003b3347b5720969a41392ae9d7344f8e4a447.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6863114833831787}","{'position': 2, 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(Nasdaq: BIIB) today announced topline results from the Phase \n2/3 XIRIUS study of cotoretigene toliparvovec (BIIB112), a gene therapy \nbeing...', 'thumbnail': 'https://serpapi.com/searches/6721ead72a48821b6e0a40e8/images/be86e02987f2e995616c50d1077f6702ca727046531578c6246c16c386ba5a9c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9064289331436157}",,,,,,,,,,['neutral'],neutral,1 NCT06197217,"{'position': 1, 'link': 'https://www.nature.com/articles/s41421-024-00673-0', 'title': 'Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04 | Cell Discovery', 'source': 'Nature', 'date': 'Apr 9, 2024', 'snippet': 'Drug resistance poses a significant challenge in the development of \neffective therapies against SARS-CoV-2. Here, we identified two double...', 'thumbnail': 'https://serpapi.com/searches/6721eadba32436e9acd160b9/images/90dbbf555be6073c4743789c5450f518de629646c43596db25204086746cf387.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5293673276901245}",,,,,,,,,,['negative'],negative,0 NCT02918279,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1916038', 'title': 'A Randomized, Controlled Trial of Liraglutide for Adolescents with Obesity', 'source': 'The New England Journal of Medicine', 'date': 'Mar 31, 2020', 'snippet': 'Obesity is a chronic disease with limited treatment options in pediatric \npatients. 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therapy with an implantable cardiac pacemaker in a patient with glioblastoma', 'source': 'Frontiers', 'date': 'Aug 22, 2024', 'snippet': '1Department of Radiation Oncology, University of Missouri, Columbia, MO, \nUnited States; 2Department of Global Medical Safety, Novocure Inc.,...', 'thumbnail': 'https://serpapi.com/searches/6721ec81f41044dc7df58c39/images/838440fed6e29b9bc520a90d80b59f98b78b5c5318e1ac0de4d286a908a896e9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.91129469871521}",,,,,,,,,,['neutral'],neutral,1 NCT00434811,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/islet-transplantation-restores-blood-sugar-awareness-control-type-1-diabetes', 'title': 'Islet transplantation restores blood sugar awareness and control in type 1 diabetes', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Apr 18, 2016', 'snippet': 'New clinical trial results show that transplantation of pancreatic islets — \ncell clusters that contain insulin-producing 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Achondroplasia', 'source': 'Medical Professionals Reference', 'date': 'Oct 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of Voxzogo \n(vosoritide) to increase linear growth in children of all ages with \nachondroplasia...', 'thumbnail': 'https://serpapi.com/searches/6721edc698876dbcc380f6f7/images/2cdbe6fc97aa08716c8ca05b589a915bd1664520fdc86e153ef1fe66683b5ea9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6303216814994812}",,,,,,,,"['neutral', 'negative', 'neutral']",neutral,1 NCT03681860,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00501-7/fulltext', 'title': 'Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial', 'source': 'The Lancet', 'date': 'Nov 24, 2023', 'snippet': 'BCG confers reduced, variable protection against pulmonary tuberculosis. A \nmore effective vaccine is needed. We evaluated the safety and...', 'thumbnail': 'https://serpapi.com/searches/6721ede3b691a77af41440cd/images/7acef9e9baadda50a4867a9f088db2b66ff3fa0ef9127269ff7cb236e1dde7f4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8410376310348511}",,,,,,,,,,['neutral'],neutral,1 NCT03938246,"{'position': 1, 'link': 'https://liverdiseasenews.com/news/denifanstat-safely-treat-nash-phase-2b-clinical-trial/', 'title': 'Denifanstat seen to safely treat NASH in Phase 2b clinical trial', 'source': 'Liver Disease News', 'date': 'Feb 5, 2024', 'snippet': 'Denifanstat outperformed a placebo at resolving nonalcoholic \nsteatohepatitis in patients with moderate to severe liver fibrosis \ntreated...', 'thumbnail': 'https://serpapi.com/searches/6721edf14a4a1d50b272fb02/images/fbb286d365e84a376173e3b640353b51b20b85c021b21448c00a8de87e719375.png', 'sentiment': 'positive', 'sentiment_prob': 0.5272930264472961}",,,,,,,,,,['positive'],positive,1 NCT02372253,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-28826-3', 'title': 'Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes', 'source': 'Nature', 'date': 'Mar 3, 2022', 'snippet': 'Currently, no oral medications are available for type 1 diabetes (T1D). \nWhile our recent randomized placebo-controlled T1D trial revealed...', 'thumbnail': 'https://serpapi.com/searches/6721edf4d9c3e646d94aa242/images/a99e5760cdf01debcb0573ee1824738da65dfec384dab92f47a558bc9e66c908.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6621863842010498}",,,,,,,,,,['neutral'],neutral,1 NCT03493269,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1267091/full', 'title': 'The role of inflammation in autoimmune disease: a therapeutic target', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': ""Autoimmune diseases (AIDs) are immune disorders whose incidence and \nprevalence are increasing year by year. AIDs are produced by the immune \nsystem's..."", 'thumbnail': 'https://serpapi.com/searches/6721ee3f5416d8e6ac1d2a86/images/499192012c7c7b27f438fed71d0057c2824f7d0f1da7e36fdd3450e9d4a970da.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.490505188703537}",,,,,,,,,,['negative'],negative,0 NCT03921528,"{'position': 1, 'link': 'https://smanewstoday.com/news/clinical-benefit-apitegromab-sustained-3-years-study/', 'title': 'Clinical benefit of apitegromab sustained for up to 3 years: Study', 'source': 'SMA News Today', 'date': 'Jul 29, 2024', 'snippet': 'Three years of treatment with apitegromab provided clinical benefit to \nchildren and young adults with SMA type 2 or 3, per a study.', 'thumbnail': 'https://serpapi.com/searches/6721ee627ebde5d98affb902/images/1f03d875282e2b8a49992dfc742f0cabc5f2913ff816039353ba287422675978.png', 'sentiment': 'positive', 'sentiment_prob': 0.6395848989486694}","{'position': 2, 'link': 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for Metastatic RCC', 'source': 'Cancer Network', 'date': 'Feb 22, 2022', 'snippet': 'The final analysis of the phase 3 IMmotion151 trial did not reveal a \nsignificant improvement in overall survival with atezolizumab plus...', 'thumbnail': 'https://serpapi.com/searches/6721eea8272a87d7f8c00cc0/images/b73e20fb6e8f8a2932e575d008c2d469db183434044c1720f9bfa50d9349711b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6603785157203674}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/sbrt-controls-metastatic-kidney-cancer-for-as-much-as-2-years-says-expert', 'title': 'SBRT Controls Metastatic Kidney Cancer ‘For As Much as 2 Years’, Says Expert', 'source': 'Cancer Network', 'date': 'Dec 4, 2022', 'snippet': 'Data from recent clinical trials indicate that stereotactic radiation can \nlocally control metastatic kidney cancer and delay systemic therapy for \nclose to 2...', 'thumbnail': 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'https://www.ucb.com/clinical-studies/Clinical-studies-index/Vimpat-lacosamide', 'title': 'Lacosamide (Vimpat®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Epilepsy, A Study to Evaluate the Efficacy and Safety of Adjunctive Therapy \nWith Lacosamide in Adults With Partial Onset Seizures, Phase 3...', 'thumbnail': 'https://serpapi.com/searches/6721eeccd0253ebcf8559a0b/images/2a85d8b6b2aab2776467a2c8e1667d15b9b14977a7593f0de9a897b547d55e8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9128645658493042}",,,,,,,,,,['neutral'],neutral,1 NCT04218266,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.120.049768', 'title': 'Stroke Prevention in Atrial Fibrillation:', 'source': 'American Heart Association Journals', 'date': 'Dec 14, 2020', 'snippet': 'Ischemic strokes related to atrial fibrillation are highly prevalent, \npresenting with severe neurologic syndromes and associated with high...', 'thumbnail': 'https://serpapi.com/searches/6721eef1671f3f3c44ac488d/images/2d2d0cc9a9476cd38d918c407c5c044654c77d5d04c1c09ba4bd81c9c22befae.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4968705475330353}",,,,,,,,,,['neutral'],neutral,1 NCT00134030,"{'position': 1, 'link': 'https://www.onclive.com/view/non-hispanic-black-children-experience-inferior-post-relapse-survival-outcomes-vs-whites-with-nonmetastatic-osteosarcoma', 'title': 'Non-Hispanic Black Children Experience Inferior Post-Relapse Survival Outcomes vs Whites With Nonmetastatic Osteosarcoma', 'source': 'OncLive', 'date': '1 month ago', 'snippet': 'R. Lor Randall, MD, FACS, discusses the relationship between poverty, race, \nethnicity, and survival outcomes in pediatric nonmetastatic...', 'thumbnail': 'https://serpapi.com/searches/6721ef0bfd3b5ab4d17bcd3e/images/512154f05df73aad71372df52f6533dea30ce410f0545627acb099bc85b0e410.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7275171279907227}",,,,,,,,,,['neutral'],neutral,1 NCT01480180,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/esperoct-hemophilia-a-prophylaxis-extended-half-life-therapy/', 'title': 'Esperoct Highly Effective as Prophylaxis for Hemophilia A, Study Suggests', 'source': 'Hemophilia News Today', 'date': 'Jan 29, 2021', 'snippet': 'Severe hemophilia A patients using Esperoct (turoctocog alfa pegol) as a \npreventive treatment do well, with fewer bleeds or breakthrough bleeds, \nlower costs,...', 'thumbnail': 'https://serpapi.com/searches/6721ef29d0d7e3e61e285a57/images/e970b096da82097e8965ea97d89851818e755e833292aa4e364a7b1ae9bc00ba.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5337181091308594}",,,,,,,,,,['positive'],positive,1 NCT04436510,"{'position': 1, 'link': 'https://alsnewstoday.com/news/als-therapy-verdiperstat-fails-healey-trial-efficacy-goals/', 'title': 'ALS Therapy Verdiperstat Fails to Meet Efficacy Goals in HEALEY Trial', 'source': 'ALS News Today', 'date': 'Oct 6, 2022', 'snippet': 'The ALS therapy verdiperstat failed to slow disease progression, improve \nsurvival, or meet other efficacy goals in the HEALEY platform...', 'thumbnail': 'https://serpapi.com/searches/6721ef7c1ec32fb22c825ff7/images/59fcb12340ac3133ba0f6b03e8b2f91cdea5c315db511bc5290774f9eddce66f.png', 'sentiment': 'negative', 'sentiment_prob': 0.7811991572380066}",,,,,,,,,,['negative'],negative,0 NCT02336074,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-42888-3', 'title': 'Therapeutic vaccination following early antiretroviral therapy elicits highly functional T cell responses against conserved HIV-1 regions | Scientific Reports', 'source': 'Nature', 'date': 'Oct 11, 2023', 'snippet': ""'Kick and kill' cure strategies aim to induce HIV protein expression in \nlatently infected cells (kick), and thus trigger their elimination..."", 'thumbnail': 'https://serpapi.com/searches/6721ef9bd9103905e0e02e2b/images/740d5ebaa5d04d9c32d7bb4c7954ee900d815b518985d16b39859e92b858388f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7719951868057251}",,,,,,,,,,['neutral'],neutral,1 NCT01942135,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1810527', 'title': 'Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 20, 2018', 'snippet': 'Palbociclib, in combination with fulvestrant therapy, prolongs \nprogression-free survival among patients with hormone-receptor–positive, \nhuman epidermal growth...', 'thumbnail': 'https://serpapi.com/searches/6721ef9cb4e8d6fcca27518f/images/a7661f5ea4099cb8afdaee62471747fe3331f33ac5044ce0668bc0a0247a4c8e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5874237418174744}","{'position': 2, 'link': 'https://www.nature.com/articles/s41698-022-00297-1', 'title': 'Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib', 'source': 'Nature', 'date': 'Aug 16, 2022', 'snippet': 'While cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, including \npalbociclib, combined with endocrine therapy (ET), are becoming the...', 'thumbnail': 'https://serpapi.com/searches/6721ef9cb4e8d6fcca27518f/images/a7661f5ea4099cb84e3a81dc54e931d271b2d3021fe5d4c30834f3325a921329.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9147531986236572}","{'position': 3, 'link': 'https://breastcancer-news.com/2018/11/05/faslodex-ibrance-combo-improves-survival-advanced-breast-cancer-patients/', 'title': 'In Breast Cancer, Ibrance-Faslodex Combo Improves Survival, Phase 3 Data Shows', 'source': 'breastcancer-news.com', 'date': 'Nov 5, 2018', 'snippet': ""Adding Pfizer's Ibrance to standard treatment Faslodex significantly \nextended the survival of advanced breast cancer patients in a Phase 3..."", 'thumbnail': 'https://serpapi.com/searches/6721ef9cb4e8d6fcca27518f/images/a7661f5ea4099cb8c82c5ae01f8c863631ab207ff47c28247f76f530c9a89bb7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.631209135055542}","{'position': 4, 'link': 'https://breastcancer-news.com/2018/03/12/ibrance-treatment-success-breast-cancer-blood-test-quick-prediction-study/', 'title': ""Test Could Quickly Predict Breast Cancer Patients' Response to Ibrance"", 'source': 'breastcancer-news.com', 'date': 'Mar 12, 2018', 'snippet': 'A new blood test could predict how a patient will respond to metastatic \nbreast cancer medication Ibrance (palbociclib) months earlier than...', 'thumbnail': 'https://serpapi.com/searches/6721ef9cb4e8d6fcca27518f/images/a7661f5ea4099cb83d68affa06f440857b82837c342d97d76595dc4aee9377c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9154565930366516}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01108445,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/EDBK_438642', 'title': 'Renal Cell Carcinoma of Variant Histology: New Biologic Understanding Leads to Therapeutic Advances', 'source': 'ASCO Publications', 'date': 'May 22, 2024', 'snippet': 'We detail recent advances in understanding the biology of RCC with variant \nhistology and how such findings have guided novel clinical studies.', 'thumbnail': 'https://serpapi.com/searches/6721ef9de45f339dd3e6beee/images/d562d7dd75da0535f0921692fc71265e5fa15808d79ff4af855bb66984e0705b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7896586060523987}",,,,,,,,,,['neutral'],neutral,1 NCT00087529,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/rituximab-for-rrms/', 'title': 'Rituximab in MS | Experimental MS Treatments', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 12, 2022', 'snippet': 'Rituximab is commonly used off-label in multiple sclerosis patients. Learn \nmore about its uses, side effects, and clinical testing.', 'thumbnail': 'https://serpapi.com/searches/6721efcfe8735a148295865b/images/ba5ae4cb867921e05314a41ef4c92e1e540e41865e548753c78f82ae8a951c6d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9291795492172241}",,,,,,,,,,['neutral'],neutral,1 NCT04976855,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/indivior-announces-dosing-of-first-subject-with-indv-2000-in-a-phase-2-study-assessing-the-safety-and-efficacy-of-indv-2000-in-individuals-with-opioid-use-disorder-302168484.html', 'title': 'Indivior Announces Dosing of First Subject with INDV-2000 in a Phase 2 Study Assessing the Safety and Efficacy of INDV-2000 in Individuals with Opioid Use Disorder', 'source': 'PR Newswire', 'date': 'Jun 10, 2024', 'snippet': 'Double-blind, placebo-controlled study aims to measure safety and efficacy \nof INDV-2000 over 3 months in participants with moderate to...', 'thumbnail': 'https://serpapi.com/searches/6721efd114c31e91e4a4d6c1/images/80b8861580baccb27fed27ee96b1d97b0406ab7f732af8c64443486210fe0815.png', 'sentiment': 'neutral', 'sentiment_prob': 0.903710126876831}",,,,,,,,,,['neutral'],neutral,1 NCT03719586,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1910993', 'title': 'A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics', 'source': 'The New England Journal of Medicine', 'date': 'Nov 27, 2019', 'snippet': 'We conducted a trial of four investigational therapies for EVD in the \nDemocratic Republic of Congo, where an outbreak began in August 2018.', 'thumbnail': 'https://serpapi.com/searches/6721efedf963e7b1d3097a47/images/7d384dc3845c98de0a1941be53c39548faeef1ef4ef26c3f8f354dc9017971ef.png', 'sentiment': 'neutral', 'sentiment_prob': 0.932693600654602}",,,,,,,,,,['neutral'],neutral,1 NCT04676178,"{'position': 1, 'link': 'https://sclerodermanews.com/news/prometheus-launching-phase-2-trial-pra023-treat-ssc-ild/', 'title': 'Phase 2 Trial of PRA023 in SSc-ILD Patients Planned for Next Year', 'source': 'Scleroderma News', 'date': 'Dec 14, 2021', 'snippet': 'Prometheus Biosciences is planning a clinical trial of its investigational \nanti-inflammatory and antifibrotic medication PRA023 in people with \nsystemic...', 'thumbnail': 'https://serpapi.com/searches/6721f0150e6db34182d00447/images/ab0c3be4cd375e57856b86588330eeb6f6430e2d249d972177ea5d9e53749d38.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8826546669006348}",,,,,,,,,,['neutral'],neutral,1 NCT00246753,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0496-4', 'title': 'Dacomitinib, but not lapatinib, suppressed progression in castration-resistant prostate cancer models by preventing HER2 increase', 'source': 'Nature', 'date': 'Jun 18, 2019', 'snippet': 'Despite overexpression of the ErbB (EGFR/HER2/ErbB3/ErbB4) family in \ncastration-resistant prostate cancer (CRPC), some inhibitors of this...', 'thumbnail': 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'https://www.empr.com/home/news/ready-to-use-liquid-glucagon-gets-approval-for-severe-hypoglycemia/', 'title': 'Ready-to-Use Liquid Glucagon Gets Approval for Severe Hypoglycemia', 'source': 'Medical Professionals Reference', 'date': 'Sep 11, 2019', 'snippet': 'The Food and Drug Administration (FDA) has approved Gvoke (glucagon; Xeris \nPharmaceuticals) for the treatment of severe hypoglycemia in pediatric and \nadult...', 'thumbnail': 'https://serpapi.com/searches/6721f07f6a5dd3bbff20e5f5/images/58117596eb4bedf4ab785d3f04cdadcbc87708652335e49851d290a63a8565c4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7991900444030762}",,,,,,,,,,['neutral'],neutral,1 NCT01357239,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/decisional-intervention-may-be-beneficial-for-parents-of-fxs-chidren/', 'title': 'Information, Support May Persuade Parents of FXS Children to Join Trials', 'source': 'Fragile X News Today', 'date': 'Feb 19, 2019', 'snippet': 'Parents of children with fragile 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approved Filsuvez (birch \ntriterpenes) to treat skin wounds in patients with dystrophic epidermolysis \nbullosa (DEB...', 'thumbnail': 'https://serpapi.com/searches/6721f0a79062f8271d86192a/images/336bd217ef51d881371ec588014ec4cb2bf63d5995e9b7e72521e657a279f326.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8094314932823181}","{'position': 4, 'link': 'https://epidermolysisbullosanews.com/news/amryt-plans-regulatory-submissions-for-filsuvez-following-positive-phase-3-data/', 'title': 'Positive EB Trial Data Puts Filsuvez on Track for Regulatory Submissions', 'source': 'Epidermolysis Bullosa News', 'date': 'Sep 23, 2020', 'snippet': 'Filsuvez, a topical formulation developed by Amryt Pharma, significantly \nimproved wound closure in people with epidermolysis bullosa in a...', 'thumbnail': 'https://serpapi.com/searches/6721f0a79062f8271d86192a/images/336bd217ef51d881344d64a986db64aa8427d656dbbc0842b2af315cbb2b7bc6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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placebo-controlled, phase 2 trial', 'source': 'The Lancet', 'date': 'Aug 8, 2019', 'snippet': 'Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in \npostmenopausal women with oestrogen receptor-positive, HER2-negative, \nearly-stage breast...', 'thumbnail': 'https://serpapi.com/searches/6721f13cfbde0d689940f6a1/images/e38a105238a7330311f0ddf4fdcc14cd8ed7a544921e441912046a14efc1fd97.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8423236608505249}",,,,,,,,,,['neutral'],neutral,1 NCT03575351,"{'position': 1, 'link': 'https://www.onclive.com/view/dr-neelapu-on-clinical-trial-data-with-car-t-cell-therapy-in-lymphoma', 'title': 'Dr Neelapu on Clinical Trial Data With CAR T-Cell Therapy in Lymphoma', 'source': 'OncLive', 'date': 'Jun 11, 2024', 'snippet': 'Sattva S. Neelapu, MD, discusses key clinical trial data that support the \nuse of CAR T-cell therapy in standard practice for patients with...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e45973416d9c11b3b519a8a5e8a87ea946949408e86b819f0593d6d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.746374785900116}","{'position': 2, 'link': 'https://www.cgtlive.com/view/kamdar-liso-cel-continued-efficacy-second-line-lbcl-3-year-follow-up', 'title': ""Manali Kamdar, MD, on Liso-Cel's Continued Efficacy in Second-Line LBCL at 3-Year Follow-up"", 'source': 'CGTLive®', 'date': 'Jun 3, 2024', 'snippet': 'The associate professor of medicine at University of Colorado discussed \nupdated follow-up data from the phase 3 TRANSFORM trial presented at...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e4597345a8a6f1d11081895edb4468cbfffd258420f51f878eda981.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9233295917510986}","{'position': 3, 'link': 'https://www.hematologyadvisor.com/features/lymphoma-tandem-meetings-2023-research-shows-favorable-results-treatment/', 'title': 'Tandem Meetings 2023: Research Shows Favorable Results for Lymphoma Subtypes', 'source': 'Hematology Advisor', 'date': 'Mar 31, 2023', 'snippet': 'Research regarding treatment for marginal zone lymphoma (MZL), large B-cell \nlymphoma (LBCL), and mantle cell lymphoma (MCL) presented at the 2023 \nTandem...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e459734d783c7c0c92fc82af4316789f43eb730c2dca8b33d661a6e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6556333303451538}","{'position': 4, 'link': 'https://www.oncnursingnews.com/view/frontline-pola-r-chp-car-t-second-line-therapy-are-not-cost-effective-choices-for-patients-with-dlbcl', 'title': 'Frontline Pola-R-CHP, CAR-T Second-Line Therapy Are Not Cost-Effective Choices For Patients With DLBCL', 'source': 'Oncology Nursing News', 'date': 'Jan 5, 2023', 'snippet': 'An economic analysis showed that neither polatuzumab vedotin nor \nCD19-directed CAR T-cell therapy are likely to be the most cost-effective...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e459734bb3ad91f5405a61b23f7e21e4665fb3743b42047fd3132e8.png', 'sentiment': 'negative', 'sentiment_prob': 0.6230538487434387}","{'position': 5, 'link': 'https://www.onclive.com/view/liso-cel-shows-improved-efs-pfs-and-durable-responses-in-second-line-lbcl-at-3-years', 'title': 'Liso-cel Shows Improved EFS, PFS, and Durable Responses in Second-line LBCL at 3 Years', 'source': 'OncLive', 'date': 'Jun 27, 2024', 'snippet': 'Lisocabtagene maraleucel (liso-cel; Breyanzi) continued to demonstrate \nimproved disease control and event-free and progression-free survival (PFS) \ncompared...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e4597341d38ad8940071b323e5fda6a66a4e202780c6e4863597982.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.656090497970581}","{'position': 6, 'link': 'https://www.onclive.com/view/fda-approval-insights-liso-cel-in-second-line-relapsed-refractory-lbcl', 'title': 'FDA Approval Insights: Liso-Cel in Second-Line Relapsed/Refractory LBCL', 'source': 'OncLive', 'date': 'Jul 28, 2022', 'snippet': 'Dr Ghosh discusses the FDA approval of lisocabtagene maraleucel in large \nB-cell lymphoma, pivotal efficacy and safety data from the phase 3...', 'thumbnail': 'https://serpapi.com/searches/6721f20dee468296d3575123/images/870f14f50e4597346d4809ef2cc091952277db3d37fe36d3c4652111c707d88f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8362480998039246}",,,,,"['neutral', 'neutral', 'neutral', 'negative', 'positive', 'neutral']",neutral,1 NCT02657343,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-021-00311-y', 'title': 'Phase 1b clinical trial of ado-trastuzumab emtansine and ribociclib for HER2-positive metastatic breast cancer', 'source': 'Nature', 'date': 'Aug 4, 2021', 'snippet': 'Patients with HER2+ metastatic breast cancer are often treated with a \nmultitude of therapies in the metastatic setting, and additional...', 'thumbnail': 'https://serpapi.com/searches/6721f24472e5c4745ca75a65/images/252b515ba591c7a4932da8546fde12d9621685a19a297b53997db32c000dbae6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8565197587013245}",,,,,,,,,,['neutral'],neutral,1 NCT04519567,"{'position': 1, 'link': 'https://friedreichsataxianews.com/friedreichs-ataxia-experimental-treatments/cti-1601/', 'title': ""CTI-1601 for Friedreich's ataxia"", 'source': ""Friedreich's Ataxia News"", 'date': 'Aug 15, 2017', 'snippet': 'Nomlabofusp, also known as CTI-1601, is a potential FA therapy by Larimar \nTherapeutics designed to increase frataxin levels.', 'thumbnail': 'https://serpapi.com/searches/6721f2c0c5d7695cb84e08ac/images/677d03c0639ba0bf116750372df90c8104a37cfd92604f6d45a0b01eee6dfed3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8881443738937378}","{'position': 2, 'link': 'https://friedreichsataxianews.com/news/first-friedreichs-ataxia-patient-dosed-ole-study-nomlabofusp/', 'title': 'First FA patient dosed in OLE study of nomlabofusp, formerly CTI-1601', 'source': ""Friedreich's Ataxia News"", 'date': 'Mar 19, 2024', 'snippet': 'The first patient has been dosed in a long-term, open-label extension (OLE) \nof a Phase 2 dose escalation study that tested nomlabofusp, formerly \nCTI-1601.', 'thumbnail': 'https://serpapi.com/searches/6721f2c0c5d7695cb84e08ac/images/677d03c0639ba0bfd584ed523e4382d2a1ee14a8dd347a54fc8b10f5e2676454.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8837335109710693}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01227278,"{'position': 1, 'link': 'https://copdnewstoday.com/news/no-reduction-copd-exacerbations-add-on-fasenra-phase-3-trials/', 'title': 'No Reduction in COPD Exacerbations with Fasenra Add-on in Phase 3 Trials', 'source': 'COPD News Today', 'date': 'Jun 11, 2019', 'snippet': 'Add-on treatment with Fasenra (benralizumab) failed to reduce annual \nexacerbations in patients with moderate to very severe COPD,...', 'thumbnail': 'https://serpapi.com/searches/6721f2cbdda9d9ba7d3b7d84/images/cdcda7f5535c5a670c6139b3a5d1426b6f6a83cc238dba29461265f9158c4bb5.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7574577331542969}",,,,,,,,,,['negative'],negative,0 NCT02610283,"{'position': 1, 'link': 'https://www.drugdiscoverytrends.com/quark-pharmaceuticals-reports-positive-phase-2-results-to-evaluate-the-efficacy-and-safety-of-qpi-1002/', 'title': 'Quark Pharmaceuticals Reports Positive Phase 2 Results to Evaluate the Efficacy and Safety of QPI-1002', 'source': 'www.drugdiscoverytrends.com', 'date': 'Jul 28, 2017', 'snippet': 'Quark Pharmaceuticals announced successful completion of a randomized, \ndouble-blinded, placebo-controlled multicenter Phase 2 trial of...', 'thumbnail': 'https://serpapi.com/searches/6721f2e7a32436e9acd167b0/images/25edf0eabe4f06cb488a996a3a29f49220d8a88bf06aa381a414d2abeb23a2c7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6692343354225159}",,,,,,,,,,['positive'],positive,1 NCT04183335,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02320-9', 'title': 'Dupilumab in patients with prurigo nodularis: two randomized, double-blind, placebo-controlled phase 3 trials', 'source': 'Nature', 'date': 'May 4, 2023', 'snippet': 'Prurigo nodularis (PN) is a chronic inflammatory skin disease with \nintensely pruritic nodules. The LIBERTY-PN PRIME and PRIME2 phase 3...', 'thumbnail': 'https://serpapi.com/searches/6721f343c05eb50a3493b07d/images/cea6edddb7ad2beb9a1f5bd40f1e6db960686f354fd2efa5b087a7899e15b161.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7423474192619324}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/significant-improvements-observed-with-dupilumab-in-prurigo-nodularis-trial/', 'title': 'Significant Improvements Observed With Dupilumab in Prurigo Nodularis Trial', 'source': 'Medical Professionals Reference', 'date': 'Jan 19, 2022', 'snippet': 'Patients with prurigo nodularis treated with dupilumab experienced a \nclinically significant reduction in itch, according to new phase 3 data.', 'thumbnail': 'https://serpapi.com/searches/6721f343c05eb50a3493b07d/images/cea6edddb7ad2beb9dfa1688cda8c84d9f06ad38153b92395419f809aa3b48be.png', 'sentiment': 'positive', 'sentiment_prob': 0.6337721347808838}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT00690274,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/systems-neuroscience/articles/10.3389/fnsys.2012.00072/full', 'title': ""Histamine H3 receptor antagonists/inverse agonists on cognitive and motor processes: relevance to Alzheimer's disease, ADHD, schizophrenia, and drug abuse"", 'source': 'Frontiers', 'date': 'Jun 30, 2024', 'snippet': 'Histamine H3 receptor (H3R) antagonists/inverse agonists possess potential \nto treat diverse disease states of the central nervous system (CNS).', 'thumbnail': 'https://serpapi.com/searches/6721f37cfab273f994d8650d/images/4733a86fa039e55260566a557aa1b7218345c0479c092722ec34c045b3fa4ad7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8685241937637329}",,,,,,,,,,['neutral'],neutral,1 NCT00088699,"{'position': 1, 'link': 'https://www.nature.com/articles/s41398-024-02956-2', 'title': 'Functional changes in sleep-related arousal after ketamine administration in individuals with treatment-resistant depression | Translational Psychiatry', 'source': 'Nature', 'date': 'Jun 4, 2024', 'snippet': 'This study sought to evaluate differences in arousal-related sleep metrics \nbetween 36 individuals with treatment-resistant major depression (TRD) and \n25...', 'thumbnail': 'https://serpapi.com/searches/6721f38d3c9575672023d861/images/81a530fb6fa2d900d73bc62c4caef82da974e57fe44b3bce20165926f17f5d8e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9081106185913086}","{'position': 2, 'link': 'https://www.researchgate.net/figure/Effects-of-ketamine-on-mood-Graphs-of-the-marginal-means-derived-from-the-linear-mixed_fig4_323433778', 'title': 'Effects of ketamine on mood. Graphs of the marginal means derived from...', 'source': 'ResearchGate', 'date': 'Dec 27, 2020', 'snippet': 'Download scientific diagram | Effects of ketamine on mood. Graphs of the \nmarginal means derived from the linear mixed models for the \nMontgomery-Åsberg...', 'thumbnail': 'https://serpapi.com/searches/6721f38d3c9575672023d861/images/81a530fb6fa2d90020eea1b59af52c6e5e932943e1824a3fb67e6087ae273aaf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9119168519973755}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02123823,"{'position': 1, 'link': 'https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01382-8', 'title': 'A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer', 'source': 'Breast Cancer Research', 'date': 'Jan 15, 2021', 'snippet': 'This phase Ib/II exploratory trial evaluated xentuzumab plus everolimus and \nexemestane in hormone receptor-positive, locally advanced and/or metastatic \nbreast...', 'thumbnail': 'https://serpapi.com/searches/6721f407d0253ebcf8559da7/images/de09b1904eb2881cb051cc0642824ff6835dda93e17a86ccc02708791d838016.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8782196044921875}",,,,,,,,,,['neutral'],neutral,1 NCT03390296,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00361-x', 'title': 'Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy', 'source': 'Nature', 'date': 'Dec 18, 2020', 'snippet': 'Here we review the development of novel therapeutics in targeting \napoptosis, receptor tyrosine kinase (RTK) signaling, hedgehog (HH) pathway, \nmitochondrial...', 'thumbnail': 'https://serpapi.com/searches/6721f407ba13f21ac051239f/images/c5e8057f41e376dce779ccb5f136ba760133a2f14b4a69fd7f7a963e7ddfa99d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8912065029144287}",,,,,,,,,,['neutral'],neutral,1 NCT02503657,"{'position': 1, 'link': 'https://pulmonaryfibrosisnews.com/news/medicinovas-mn-001-ipf-fails-slow-lung-function-decline-trial/', 'title': ""MediciNova's MN-001 for IPF Fails to Slow Lung Function Decline in Trial"", 'source': 'Pulmonary Fibrosis News', 'date': 'Aug 23, 2021', 'snippet': 'Six months of treatment with MN-001 failed to significantly improve lung \nfunction in adults with idiopathic pulmonary fibrosis, data show.', 'thumbnail': 'https://serpapi.com/searches/6721f427cc29875e745349e9/images/7a3d1b25fdd5fbcdad8950ee991973e7b2045315aa2c5acb7ae510d39bbeb74b.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8319323658943176}",,,,,,,,,,['negative'],negative,0 NCT04286750,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332221011471', 'title': 'Target engagement of the first-in-class CXCR7 antagonist ACT-1004-1239 following multiple-dose administration in mice and humans', 'source': 'ScienceDirect.com', 'date': 'Oct 28, 2021', 'snippet': 'Here, we report the target engagement of ACT-1004-1239 in healthy mice and \nhumans after multiple doses using CXCL11 and CXCL12 as biomarkers.', 'thumbnail': 'https://serpapi.com/searches/6721f430e45f339e017337f0/images/c1238da527b52c07829c8d0d26a114a7e1bc291d0af90df1c455a8f4bf2bc5ad.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7495174407958984}",,,,,,,,,,['neutral'],neutral,1 NCT02743221,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-01737-2', 'title': 'First-line trifluridine/tipiracil + bevacizumab in patients with unresectable metastatic colorectal cancer: final survival analysis in the TASCO1 study | British Journal of Cancer', 'source': 'Nature', 'date': 'Apr 19, 2022', 'snippet': 'The use of trifluridine/tipiracil plus bevacizumab (TT-B) in this setting \nwas evaluated in the TASCO1 trial; here, we present the final overall \nsurvival (OS)...', 'thumbnail': 'https://serpapi.com/searches/6721f452ee677f6cfefc7574/images/ab577a588653f5d6911715bc422a0f74677742f81f020950df32428b1e7a57aa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8699007034301758}",,,,,,,,,,['neutral'],neutral,1 NCT01522820,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1255799/full', 'title': 'Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment', 'source': 'Frontiers', 'date': 'Feb 7, 2024', 'snippet': 'Here, we summarized the current advances in cancer vaccines targeting \nNY-ESO-1 for solid cancer treatment, aiming to provide perspectives for \nfuture research.', 'thumbnail': 'https://serpapi.com/searches/6721f4584d52b8a072853b6e/images/ca52ad25d09cf093b916163c2c4600f3f2bb161fe78283349ebeedb6bff5f41d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.875281810760498}",,,,,,,,,,['neutral'],neutral,1 NCT05261191,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-024-01176-4', 'title': 'Bridging the gap with multispecific immune cell engagers in cancer and infectious diseases', 'source': 'Nature', 'date': 'May 24, 2024', 'snippet': 'By binding to multiple antigens simultaneously, multispecific antibodies \nare expected to substantially improve both the activity and...', 'thumbnail': 'https://serpapi.com/searches/6721f46a49ea55cde45bbb81/images/30f43337d8013f0c50e3aaad03efadd1e3b4a02a294dc8bd877d45522cb2a8f1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7509574294090271}",,,,,,,,,,['neutral'],neutral,1 NCT02928224,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1908075', 'title': 'Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 30, 2019', 'snippet': 'Patients with metastatic colorectal cancer with the BRAF V600E mutation \nhave a poor prognosis, with a median overall survival of 4 to 6...', 'thumbnail': 'https://serpapi.com/searches/6721f4a39109867ea0071961/images/669cb36c7f3370665a023c8eef0370a7ef537eae6b6a16dcc4626c39b9190072.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6425409317016602}","{'position': 2, 'link': 'https://coloncancernewstoday.com/2017/06/01/microsatellite-stable-colorectal-cancer-patients-focus-binimetinib-opdivo-yervoy-trial/', 'title': 'Microsatellite Stable Colorectal Cancer Patients Focus of Binimetinib-Opdivo-Yervoy Trial', 'source': 'Colon Cancer News Today', 'date': 'Jun 1, 2017', 'snippet': 'The MEK inhibitor, binimetinib, will soon be tested in combination with \nOpdivo plus Yervoy in colorectal cancer patients with microsatellite...', 'thumbnail': 'https://serpapi.com/searches/6721f4a39109867ea0071961/images/669cb36c7f337066d1ad0eed2682022e5b4c49cb14197172e803f03adddc1cce.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9217116236686707}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT02252016,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/zepatier-effective-against-hcv-infection-in-sickle-cell-blood-disorders-in-clinical-trial/', 'title': 'Sickle Cell Patients with HCV Infection Treated with Zepatier in Phase 3 Study', 'source': 'Sickle Cell Disease News', 'date': 'Mar 9, 2017', 'snippet': 'Results of a Phase 3 clinical trial in sickle cell and other blood disorder \npatients found Zepatier an effective antiviral agent against HCV...', 'thumbnail': 'https://serpapi.com/searches/6721f4d588bcdefebd9aad46/images/375d5e6c8e991f408ebec79d5e2f73b16843c7d70e94e909de741850d57868fe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8537318706512451}",,,,,,,,,,['neutral'],neutral,1 NCT04435366,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/astellas-to-acquire-iveric-bio-for-5-9b-expanding-eye-disease-pipeline/', 'title': 'Astellas to Acquire Iveric Bio for $5.9B, Expanding Eye Disease Pipeline', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'May 1, 2023', 'snippet': ""Astellas Pharma has agreed to acquire Iveric Bio for approximately $5.9 \nbillion, the companies said today, in a deal designed to expand the buyer's \npipeline of..."", 'thumbnail': 'https://serpapi.com/searches/6721f4dcc76a22ae2333611e/images/2ff36dd471b9d5666a6dbfa6a0c1bbbbc6ed834710d46bbb961ec1a28350ed9f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8609184622764587}",,,,,,,,,,['neutral'],neutral,1 NCT01524289,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/circ.130.suppl_2.9613', 'title': 'Abstract 9613: Randomized Evaluation of Anacetrapib Lipid-Modifying Therapy in Patients With HeteroZygous Familial HypercholesterolEmia (REALIZE Study)', 'source': 'American Heart Association Journals', 'date': 'Nov 25, 2014', 'snippet': 'Introduction: Anacetrapib, a cholesteryl ester transfer protein inhibitor, \nhas been shown to robustly reduce atherogenic lipoproteins...', 'thumbnail': 'https://serpapi.com/searches/6721f4e7b2ebaeb5ae24b6e2/images/8909766d64db820d44a94c72eed94f5cad439a9888e9d5c8301aa9f9f862d165.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8853394389152527}",,,,,,,,,,['neutral'],neutral,1 NCT04402489,"{'position': 1, 'link': 'https://porphyrianews.com/news/mt-7117-eases-sunlight-sensitivity-epp-xlp-patients-phase-2-trial/', 'title': 'MT-7117 found to ease sunlight sensitivity for EPP, XLP patients |...', 'source': 'Porphyria News', 'date': 'Apr 19, 2023', 'snippet': 'The oral therapy MT-7117 was found to ease sunlight sensitivity and improve \nlife quality for porphyria patients in a Phase 2 trial.', 'thumbnail': 'https://serpapi.com/searches/6721f53b69f8eca1f4572dd3/images/7901fa1f41508116d9dc59999af81bf9402ae63bb96fe15801661d918bb2600a.png', 'sentiment': 'positive', 'sentiment_prob': 0.5625188946723938}","{'position': 2, 'link': 'https://porphyrianews.com/phase-3-trial-mt-7117-for-epp-xlp-porphyrias/', 'title': 'MT-7117 Poised for Phase 3 Trial in Two Types of Porphyrias', 'source': 'Porphyria News', 'date': 'May 29, 2020', 'snippet': ""A Phase 3 clinical trial of Mitsubishi Tanabe's investigational therapy \nMT-7117 (dersimelagon) for people with erythropoietic protoporphyria..."", 'thumbnail': 'https://serpapi.com/searches/6721f53b69f8eca1f4572dd3/images/7901fa1f4150811609d12cffbc89610c0d9bace28fddf00271fba67a487e311f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8879155516624451}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04535986,"{'position': 1, 'link': 'https://copdnewstoday.com/news/benefits-ensifentrine-copd-seen-among-patient-subgroups/', 'title': 'Benefits of ensifentrine for COPD seen among subgroups of patients', 'source': 'COPD News Today', 'date': 'Oct 23, 2023', 'snippet': ""Phase 3 analyses continue to show ensifentrine's benefits, even when \npatients are separated by exacerbation history, background therapy."", 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb124185e4f2b142e223761532d7360626a24f64ccca995ab6e326f.png', 'sentiment': 'positive', 'sentiment_prob': 0.7557270526885986}","{'position': 2, 'link': 'https://www.drugtopics.com/view/fda-approves-ensifentrine-for-treatment-of-copd', 'title': 'FDA Approves Ensifentrine for Treatment of COPD', 'source': 'Drug Topics', 'date': 'Jun 27, 2024', 'snippet': 'The FDA has approved ensifentrine (Ohtuvayre) for the maintenance treatment \nof chronic obstructive pulmonary disease (COPD) in adult patients.', 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb12418fad6914dc4f0e0f2656711344904d148038c5122388cc968.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7171338796615601}","{'position': 3, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/nebulized-ensifentrine-significantly-improves-lung-function-copd-symptoms/', 'title': 'Nebulized Ensifentrine Significantly Improves Lung Function, COPD Symptoms', 'source': 'Medical Professionals Reference', 'date': 'Dec 20, 2022', 'snippet': 'Treatment with nebulized ensifentrine resulted in significant improvements \nin lung function and reduced the rate and risk of chronic obstructive \npulmonary...', 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb1241849101317d2ea671e474739a196b52d114740c8527bd491a8.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6964200139045715}","{'position': 4, 'link': 'https://copdnewstoday.com/news/fda-decision-ensifentrine-expected-june-26-next-year-verona/', 'title': ""FDA's decision on ensifentrine for COPD expected by June 26 next..."", 'source': 'COPD News Today', 'date': 'Sep 18, 2023', 'snippet': ""The U.S. Food and Drug Administration (FDA) has agreed to review Verona \nPharma's application seeking approval of inhaled ensifentrine as a..."", 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb124187ec230864fb363c4b58e9b8bb6168790820c5f28117d5c48.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9323532581329346}","{'position': 5, 'link': 'https://copdnewstoday.com/news/first-copd-patient-dosed-ensifentrine-enhance-china-trial/', 'title': 'Dosing with ensifentrine begins in ENHANCE China trial | Phase 3...', 'source': 'COPD News Today', 'date': 'Apr 24, 2023', 'snippet': 'Dosing with ensifentrine, a nebulized inhalation therapy, has begun in a \nPhase 3 trial in China in adults with moderate-to-severe COPD.', 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb12418dd7b3575f4f4040903a5f94e28569c8cd5886448c1d4fe63.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9163825511932373}","{'position': 6, 'link': 'https://copdnewstoday.com/news/inhaled-ensifentrine-improves-lung-function-phase-3-trial-shows/', 'title': 'Inhaled Ensifentrine Improves Lung Function, Phase 3 Trial Shows |...', 'source': 'COPD News Today', 'date': 'Aug 22, 2022', 'snippet': 'Ensifentrine safely and effectively improved lung function and reduced the \nrate and risk of exacerbations in COPD patients in a trial.', 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb12418c78b1bfa7a8bef69071d989776bb2dc06e53eca4c9a252c8.png', 'sentiment': 'positive', 'sentiment_prob': 0.7553162574768066}","{'position': 7, 'link': 'https://copdnewstoday.com/news/directrx-pharmacy-distributing-copd-therapy-ohtuvayre-us/', 'title': 'DirectRx pharmacy distributing COPD therapy Ohtuvayre in US', 'source': 'COPD News Today', 'date': '1 month ago', 'snippet': 'DirectRx, a specialty pharmacy for people with chronic health disorders, is \nnow part of the exclusive US pharmacy network distributing Ohtuvayre \n(ensifentrine).', 'thumbnail': 'https://serpapi.com/searches/6721f54e88bcdefebd9aada0/images/88f8c7879eb12418cca5e89a56b47a6a428bcf3dae348759ddcc42a6878d0683.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9034528732299805}",,,,"['positive', 'neutral', 'positive', 'neutral', 'neutral', 'positive', 'neutral']",neutral,1 NCT02515838,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/phase-1-trial-test-under-the-skin-injection-sevuparin-scd/', 'title': 'Phase 1 Trial to Test Under-the-Skin Injection of Sevuparin for SCD', 'source': 'Sickle Cell Disease News', 'date': 'Nov 8, 2018', 'snippet': ""The U.S. FDA granted investigational new drug status to Modus Therapeutics' \nlead candidate, sevuparin, for the treatment of sickle cell..."", 'thumbnail': 'https://serpapi.com/searches/6721f6075f9778877f2124d8/images/90631cf744bc5d02d0b35dbd9b0f5f298811f4e2f51bcb9b33b73050be43a23e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8796523809432983}",,,,,,,,,,['neutral'],neutral,1 NCT00949650,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.2012.44.2806', 'title': 'Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Mar 19, 2019', 'snippet': 'PurposeThe LUX-Lung 3 study investigated the efficacy of chemotherapy \ncompared with afatinib, a selective, orally bioavailable ErbB family \nblocker that...', 'thumbnail': 'https://serpapi.com/searches/6721f669ee677f6d30537119/images/d3a4de43486de8dc20736b3b03f85987c9a4d21e598b1da4e2847b266cf87871.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9063786864280701}",,,,,,,,,,['neutral'],neutral,1 NCT02201940,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1512610', 'title': 'Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection', 'source': 'The New England Journal of Medicine', 'date': 'Nov 16, 2015', 'snippet': 'A simple treatment regimen that is effective in a broad range of patients \nwho are chronically infected with the hepatitis C virus (HCV)...', 'thumbnail': 'https://serpapi.com/searches/6721f67a9109867ed40002d2/images/be40677dbf804e199993461eda05716c436e045cc49d160b26bbd17135a3f3d8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8235917091369629}",,,,,,,,,,['neutral'],neutral,1 NCT00150709,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Keppra-levetiracetam', 'title': 'Levetiracetam (Keppra®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Epilepsy, A Study of Levetiracetam as Monotherapy or Adjunctive Treatment \nof Partial Seizures in Pediatric Epileptic Subjects Ranging From 1...', 'thumbnail': 'https://serpapi.com/searches/6721f6823c944b515f583773/images/d32e44ee6f43434cf0bf14b0265df95b4e28c916cc3eac10ed882145127cd1e8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9234092831611633}",,,,,,,,,,['neutral'],neutral,1 NCT03889639,"{'position': 1, 'link': 'https://www.ajmc.com/view/tolebrutinib-long-term-data-continue-to-show-the-btk-inhibitor-is-safe-clinically-effective-in-ms', 'title': 'Tolebrutinib Long-term Data Continue to Show the BTK Inhibitor Is Safe, Clinically Effective in MS', 'source': 'AJMC', 'date': 'Apr 24, 2023', 'snippet': 'Safety and clinical efficacy data through 120 weeks from a long-term \nextension study of an ongoing phase 2b dose-finding study of...', 'thumbnail': 'https://serpapi.com/searches/6721f583bcd652e60fd895ab/images/2d222d27ca60e226e5925aec4497a8bf061a3b7a500989036466f354e1f1fc38.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7259016633033752}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/tolebrutinib-multiple-sclerosis/', 'title': 'Tolebrutinib in MS | Experimental MS Treatments', 'source': 'Multiple Sclerosis News Today', 'date': 'May 25, 2022', 'snippet': 'Tolebrutinib is an oral antibiotic being evaluated as a potential treatment \nfor MS. Learn more about its uses, side effects, and clinical...', 'thumbnail': 'https://serpapi.com/searches/6721f583bcd652e60fd895ab/images/2d222d27ca60e2265bf296353ab71ab9415a0a4a9b8a7b7a7746e823f9ac3402.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9278059601783752}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/10/16/ectrims-2023-tolebrutinib-prevents-relapses-lesions-3-years/', 'title': 'ECTRIMS 2023: Tolebrutinib found to show benefits for up to 3 years', 'source': 'Multiple Sclerosis News Today', 'date': 'Oct 16, 2023', 'snippet': 'Three years of treatment with tolebrutinib was linked to low relapses rates \nand few new brain lesions among relapsing MS patients,...', 'thumbnail': 'https://serpapi.com/searches/6721f583bcd652e60fd895ab/images/2d222d27ca60e226afeef83364794bb5287556f464c545a9649e655136764630.png', 'sentiment': 'positive', 'sentiment_prob': 0.7722958922386169}",,,,,,,,"['positive', 'neutral', 'positive']",positive,1 NCT03757325,"{'position': 1, 'link': 'https://www.nature.com/articles/s41573-020-0071-y', 'title': 'Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target', 'source': 'Nature', 'date': 'Jul 15, 2020', 'snippet': 'Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a key \nmediator of cell death and inflammation.', 'thumbnail': 'https://serpapi.com/searches/6721f5ae8b84c46faaa3ebad/images/78d801c76955ff9f1fa6cbb2b254d39e46a6a970f1b9a74013fe08d6762460de.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.4965638518333435}",,,,,,,,,,['negative'],negative,0 NCT03748784,"{'position': 1, 'link': 'https://www.cureus.com/articles/110149-ocular-gene-therapy-a-literature-review-with-focus-on-current-clinical-trials', 'title': 'Ocular Gene Therapy: A Literature Review With Focus on Current Clinical Trials', 'source': 'Cureus', 'date': 'Sep 24, 2022', 'snippet': 'Gene therapy has been one of the most researched topics in the last decade. \nIt has now become a revolutionized therapeutic tool of modern...', 'thumbnail': 'https://serpapi.com/searches/6721f5f6cb33d0118fb660a6/images/bebcbd110436bc69cc66cbf2547fbfb74fe3315388f6001544dfe72d1879f0ae.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8775461316108704}",,,,,,,,,,['positive'],positive,1 NCT03036813,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1903212', 'title': 'A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease', 'source': 'The New England Journal of Medicine', 'date': 'Jun 14, 2019', 'snippet': 'In this phase 3 randomized, placebo-controlled trial involving participants \nwith sickle cell disease, voxelotor significantly increased hemoglobin \nlevels and...', 'thumbnail': 'https://serpapi.com/searches/6721f6a264f11dc06ff496f5/images/6a550cccdb4ddb4ded33022936bb76d2faae67d148ca905e6ddbd946a221d515.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9134081602096558}","{'position': 2, 'link': 'https://sicklecellanemianews.com/news/voxelotor-may-reduce-severity-number-leg-ulcers-analysis-trial-results-suggests/', 'title': 'Voxelotor May Reduce Severity and Number of Leg Ulcers, Trial Analysis Suggests', 'source': 'Sickle Cell Disease News', 'date': 'Oct 22, 2019', 'snippet': 'Voxelotor can reduce the severity of existing leg ulcers and the incidence \nof new ones in people with sickle cell disease (SCD), new clinical trial \nresults...', 'thumbnail': 'https://serpapi.com/searches/6721f6a264f11dc06ff496f5/images/6a550cccdb4ddb4da5715b55052c2771694d267e356bba06b4b13047ba1330c7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.828925609588623}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04238793,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-novartis-terminate-phase-ii-als-trial-after-benefit-risk-worry/', 'title': 'Pipeline Moves: Novartis terminates Phase II ALS trial after benefit-risk worry', 'source': 'Clinical Trials Arena', 'date': 'Aug 6, 2024', 'snippet': ""On this week's Pipeline Moves, the Clinical Trials Arena team investigates \nassets in the central nervous system, oncology and immunology."", 'thumbnail': 'https://serpapi.com/searches/6721f6a5caddc31d1631838e/images/b1263d98d8309401eedcdd9f45324a016f36c9fce75c281c11b9bcc55df77b5a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7738231420516968}",,,,,,,,,,['neutral'],neutral,1 NCT03461289,"{'position': 1, 'link': 'https://smanewstoday.com/news/canadian-agency-favors-zolgensma-only-for-babies-up-to-6-months-old/', 'title': 'Zolgensma Favored Only for SMA Babies Up to 6 Months Old in Canada', 'source': 'SMA News Today', 'date': 'Oct 6, 2021', 'snippet': 'A Canadian agency found evidence lacking to support gene therapy \nreimbursement in older babies and toddlers with spinal muscular atrophy.', 'thumbnail': 'https://serpapi.com/searches/6721f6e69e5bd52d11a9e220/images/af9da5f7e38277959e02b3b37f1ff32d67f75021bce1834a91a7c25b01d8cc07.png', 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as REGN-COV2), a combination of the monoclonal \nantibodies casirivimab and imdevimab, has been shown to markedly...', 'thumbnail': 'https://serpapi.com/searches/6721f7a1272a87d825ae80ef/images/3499858b27b6742332a764b6f5a6cc155256ce9d37979cac9db923ed9e39ffaa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8475948572158813}",,,,,,,,,,['neutral'],neutral,1 NCT00911495,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/phase-3-trial-recruiting-to-test-rivipansel-for-vaso-occlusive-crisis-in-sickle-cell-disease/', 'title': 'Clinical Trial Seeking Vaso-Occlusive Sickle Cell Patients to Test Rivipansel', 'source': 'Sickle Cell Disease News', 'date': 'May 11, 2017', 'snippet': 'A Phase 3 clinical trial to test the effectiveness and safety of the drug \ncandidate rivipansel (GMI-1070) for the treatment of vaso-occlusive crisis \n(VOC) in...', 'thumbnail': 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'IL-2 immunotherapy for targeting regulatory T cells in autoimmunity', 'source': 'Nature', 'date': 'Sep 23, 2023', 'snippet': 'A new and promising focus in drug development are IL-2-based approaches for \nin vivo targeted expansion of T reg or for enhancement of their \nsuppressive...', 'thumbnail': 'https://serpapi.com/searches/6721f80898fad682efca3473/images/efbbb53cb81c8092aed5780a5cd213dad6a8359ea438b3fc3f772c577a4114be.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6119940280914307}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01817530,"{'position': 1, 'link': 'https://endometriosisnews.com/2017/11/06/elagolix-seen-to-lessen-endometriosis-pain-and-spread-in-yearlong-phase-3-studies/', 'title': 'Elagolix Seen to Ease Endometriosis Pain and Spread in Yearlong Phase 3 Studies', 'source': 'endometriosisnews.com', 'date': 'Nov 6, 2017', 'snippet': 'Results of two Phase 3 extension studies showed that one year of treatment \nwith elagolix could reduce pelvic pain, prevent 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Here, we report interim findings on the primary...', 'thumbnail': 'https://serpapi.com/searches/6721f9ad6f9f6391afca334f/images/99b9c2f2d700289d50d356774ba573672caf35e4f417325c02cf6def9bebfc7f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8802207112312317}",,,,,,,,,,['neutral'],neutral,1 NCT02004522,"{'position': 1, 'link': 'https://lymphomanewstoday.com/2019/10/29/copiktra-superior-arzerra-cll-sll-patients-with-2-prior-therapies/', 'title': 'Copiktra Superior to Arzerra for CLL/SLL Patients with Prior Therapies, Data Suggest', 'source': 'Lymphoma News Today', 'date': 'Oct 29, 2019', 'snippet': 'Copiktra doubles response rates and extends the time until disease \nprogression or death in CLL/SLL patients with at least two prior...', 'thumbnail': 'https://serpapi.com/searches/6721f9af56f970a143a4d461/images/eb7736cf2df35e1f6a3dfc288c1c1858eb2ee289bf2c8ae0720bd0129be31d44.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9011181592941284}","{'position': 2, 'link': 'https://lymphomanewstoday.com/2019/11/01/copiktra-possible-treatment-option-advanced-marginal-zone-lymphoma-trial-data-show/', 'title': 'Copiktra May Be Treatment Option for Advanced Marginal Zone Lymphoma, Trial Data Show', 'source': 'Lymphoma News Today', 'date': 'Nov 1, 2019', 'snippet': 'The Phase 2 DYNAMO trial included 18 people with refractory marginal zone \nlymphoma, and found that seven of them responded to Copiktra...', 'thumbnail': 'https://serpapi.com/searches/6721f9af56f970a143a4d461/images/eb7736cf2df35e1ff3daf2098154a4d76f5a68048a25429a9c50218affdef3d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7104657888412476}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04115293,"{'position': 1, 'link': 'https://myastheniagravisnews.com/news/mda-2024-zilbrysq-benefits-sustained-over-1-year-gmg-study/', 'title': 'MDA 2024: Benefits of Zilbrysq sustained over 1 year in gMG study', 'source': 'Myasthenia Gravis News', 'date': 'Mar 12, 2024', 'snippet': 'Clinical responses to the approved generalized myasthenia gravis (gMG) \ntherapy Zilbrysq (zilucoplan) have now been sustained for more than a...', 'thumbnail': 'https://serpapi.com/searches/6721f9babcd652e5decfc171/images/dbb23267913df3c1905c576e1bfedaa8a3d9c62208154dad6ce4d0870e9c96b8.png', 'sentiment': 'positive', 'sentiment_prob': 0.6832995414733887}","{'position': 2, 'link': 'https://news.unchealthcare.org/2022/05/ucb-presents-efficacy-and-safety-results-for-zilucoplan-and-rozanolixizumab-in-generalized-myasthenia-gravis/', 'title': 'UCB Presents Efficacy, Safety Results for Zilucoplan, Rozanolixizumab for Generalized Myasthenia Gravis', 'source': 'UNC Health', 'date': 'May 10, 2022', 'snippet': 'UCB, a global biopharmaceutical company, announced results from two phase 3 \nstudies evaluating its investigational treatments, zilucoplan.', 'thumbnail': 'https://serpapi.com/searches/6721f9babcd652e5decfc171/images/dbb23267913df3c1e25fdb13bd59762331262e6f7663e63a8c2f83a7c11d9cad.jpeg', 'sentiment': 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'source': 'Frontiers', 'date': 'Feb 10, 2024', 'snippet': 'We review the physiology and pathological effects of Neuropilin-1, a \ntransmembrane co-receptor which mediates signal transduction pathways when \nassociated with...', 'thumbnail': 'https://serpapi.com/searches/6721f9d9f60b6f501487e394/images/b998b28e7b62e708c278ec80d5879024b2f8f4d065df38348db22e4b9aabdc19.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9102723002433777}",,,,,,,,,,['neutral'],neutral,1 NCT03153111,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/abs/10.1161/CIR.0000000000001079', 'title': 'Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action: A Science Advisory From the American Heart Association | Circulation', 'source': 'American Heart Association Journals', 'date': 'Jul 11, 2022', 'snippet': 'This science advisory focuses on the need to better understand the \nepidemiology, pathophysiology, and 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Announces Topline Results from Phase 2 Study of AR1001 in Mild to Moderate Alzheimer’s Patients', 'source': 'Business Wire', 'date': 'Nov 4, 2021', 'snippet': 'AriBio, a clinical-stage biopharmaceutical company based in South Korea, \nannounced today, the topline results from its phase 2 study of...', 'thumbnail': 'https://serpapi.com/searches/6721fa108de63cccedebb9e4/images/996ae48ecbdecbc2fd9154b0c35bf74743eab901def5a06fb935833de3a6d16a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9163773655891418}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00460096,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/clinical-trial-compares-glassia-prolastin-for-alpha1-antitrypsin-deficiency/', 'title': 'Clinical Trial Compares Glassia, Prolastin for Alpha1-Antitrypsin Deficiency', 'source': 'Pulmonology Advisor', 'date': 'Apr 27, 2022', 'snippet': 'Treatment of AAD with either Glassia or Prolastin appeared equally \neffective in a recent clinical trial of the 2 A1PI.', 'thumbnail': 'https://serpapi.com/searches/6721fa35707fd32d1eac13d5/images/968e27982076c1b00a61e2e1ac52caf91fe04558b228e8b13e9b88aba72d9f2c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8398064970970154}",,,,,,,,,,['neutral'],neutral,1 NCT02231008,"{'position': 1, 'link': 'https://geneticobesitynews.com/2020/08/20/hetlioz-granted-fda-priority-review-for-smith-magenis-syndrome/', 'title': 'FDA Grants Priority Review to Sleep Disorder Therapy Hetlioz for Smith-Magenis Syndrome', 'source': 'geneticobesitynews.com', 'date': 'Aug 20, 2020', 'snippet': ""The US Food and Drug Administration (FDA) has accepted and given priority \nreview to Vanda Pharmaceuticals' request seeking the approval of Hetlioz \n(tasimelteon)"", 'thumbnail': 'https://serpapi.com/searches/6721fa76bd7cf0d6d117fae1/images/729f5ecd6980e3ac0fdeb4514bae34b5621d2848c419880ef3dcdb05336ea9f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8270958662033081}",,,,,,,,,,['neutral'],neutral,1 NCT02576795,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/roctavian-effective-hemophilia-a-over-7-years-trial-update/', 'title': 'Single dose of Roctavian effective over 7 years, per new trial update', 'source': 'Hemophilia News Today', 'date': 'Feb 7, 2024', 'snippet': 'A single dose of Roctavian (valoctocogene roxaparvovec-rvox) sustainably \nreduced the yearly bleeding rate in adults with severe hemophilia A by up \nto 96%.', 'thumbnail': 'https://serpapi.com/searches/6721fb9ddc969f7233129c9e/images/0b320e46038e1fe503c72b8675380f16df73f43d7fc9e77daed7c962312afd2f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6956309676170349}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1908490', 'title': 'Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A', 'source': 'The New England Journal of Medicine', 'date': 'Jan 1, 2020', 'snippet': 'We report durable efficacy, long-term safety, and clinical and biologic \nresults in 15 adults with severe hemophilia A (factor VIII level, ≤1 IU per \ndeciliter)', 'thumbnail': 'https://serpapi.com/searches/6721fb9ddc969f7233129c9e/images/0b320e46038e1fe5a97af655c9a02eb4f68a9da228cd9c3c58cae6d887d5d94c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6912418007850647}","{'position': 3, 'link': 'https://hemophilianewstoday.com/news/roctavian-zeroes-bleeds-prophylaxis-need-7-years/', 'title': 'Roctavian nearly zeroes out bleeds, prophylaxis need over 7 years', 'source': 'Hemophilia News Today', 'date': 'Aug 20, 2024', 'snippet': 'A single dose of Roctavian nearly zeroed out the number of bleeds and the \nneed for prophylaxis for as long as seven years, per trial data.', 'thumbnail': 'https://serpapi.com/searches/6721fb9ddc969f7233129c9e/images/0b320e46038e1fe5f98375c3ad21aab34760fed93145731525d40514a1d4fc87.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8004980683326721}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02746796,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/home/cancer-topics/gastrointestinal-cancers/nivolumab-prolongs-gastric-cancer-gej-prolongs-survival-treatment-risk/', 'title': 'Nivolumab Prolongs PFS, Not OS in Advanced Gastric/GEJ Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Feb 7, 2022', 'snippet': 'Adding nivolumab to first-line oxaliplatin-based chemotherapy improved \nprogression-free survival in HER2-negative, advanced gastric/GEJ...', 'thumbnail': 'https://serpapi.com/searches/6721fbcfa505f73e63923a53/images/a0378da5f28d05602bbae515c375903f37198f941007c6f56452dccb61a2cc22.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.799066960811615}",,,,,,,,,,['neutral'],neutral,1 NCT00256750,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1506027', 'title': 'Belatacept and Long-Term Outcomes in Kidney Transplantation', 'source': 'The New England Journal of Medicine', 'date': 'Jan 28, 2016', 'snippet': 'In previous analyses of BENEFIT, a phase 3 study, belatacept-based \nimmunosuppression, as compared with cyclosporine-based immunosuppression,...', 'thumbnail': 'https://serpapi.com/searches/6721fbdf5ddfba5b08c6799f/images/7e271d815052706847d4e4ba8119a6a2fd0744d1341577ee1267e459f12821da.png', 'sentiment': 'neutral', 'sentiment_prob': 0.896232008934021}",,,,,,,,,,['neutral'],neutral,1 NCT04563702,"{'position': 1, 'link': 'https://www.europeanpharmaceuticalreview.com/news/130177/first-patient-dosed-in-covid-19-vaccine-tablet-clinical-trial/', 'title': 'First patient dosed in COVID-19 vaccine tablet clinical trial', 'source': 'European Pharmaceutical Review', 'date': 'Oct 14, 2020', 'snippet': 'A Phase I clinical trial to test VXA-CoV2-1, an oral tablet COVID-19 \nvaccine candidate, has been initiated with the first patient dosed.', 'thumbnail': 'https://serpapi.com/searches/6721fc03cf32e0c265e3d982/images/d8077cad6f8674fd8472bf4ab64e3ebca42fbffcaed7cb97c455b18f617319cb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8912301063537598}","{'position': 2, 'link': 'https://www.genengnews.com/news/vaxart-and-emergent-biosolutions/', 'title': 'Vaxart, Emergent BioSolutions, and Kindred Biosciences – VXA-CoV2-1', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'May 18, 2020', 'snippet': 'Candidate: VXA-CoV2-1. Category: VAX. Type: Oral recombinant vaccine \nadministered by room temperature-stable tablet, and based on...', 'thumbnail': 'https://serpapi.com/searches/6721fc03cf32e0c265e3d982/images/d8077cad6f8674fd8fb732de6ef7acf4c4cbff399e34ceac5a89b3a635466053.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9251697063446045}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01720667,"{'position': 1, 'link': 'https://www.empr.com/home/news/sezaby-approved-to-treat-seizures-in-term-and-preterm-infants/', 'title': 'Sezaby Approved to Treat Seizures in Term and Preterm Infants', 'source': 'Medical Professionals Reference', 'date': 'Nov 21, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Sezaby™ (phenobarbital \nsodium powder for injection) for the treatment of neonatal...', 'thumbnail': 'https://serpapi.com/searches/6721fc5281bab782be64802c/images/e80ab601be883bd0c80b7cbb6f6d881b911d359f74e7ebdd7052cfd1c36b58c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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that tested Dupixent (dupilumab) in people with chronic \nobstructive...', 'thumbnail': 'https://serpapi.com/searches/6721fc585809e72491958a84/images/48e54fc7bcfcd5a1e7f44aa5c0b6d24ca90b59347c7eaa6eb7554ee281c6717f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9244242310523987}","{'position': 3, 'link': 'https://copdnewstoday.com/news/dupixent-prevents-copd-exacerbations-improves-lung-function-trial/', 'title': 'Dupixent found to prevent COPD exacerbations in Phase 3 trial |...', 'source': 'COPD News Today', 'date': 'Apr 3, 2023', 'snippet': 'Dupixent (dupilumab) — a medication initially approved for exzema — was \nfound to significantly reduce the number of disease exacerbations and to...', 'thumbnail': 'https://serpapi.com/searches/6721fc585809e72491958a84/images/48e54fc7bcfcd5a17bf21571afb98310eb7b7bd135c1ce03742b24bb82d0d9fc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6353323459625244}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT05032859,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/tapinarof-cream-eases-atopic-dermatitis-in-patients-as-young-as-2-years/', 'title': 'Tapinarof Cream Eases Atopic Dermatitis in Patients as Young as 2 Years', 'source': 'Medical Professionals Reference', 'date': 'Mar 15, 2023', 'snippet': 'Tapinarof cream was found to be beneficial for atopic dermatitis patients \nas young as 2 years old, according to findings from the phase 3...', 'thumbnail': 'https://serpapi.com/searches/6721fc8ca9210b1b4b6ba22d/images/ed7f05be4dc411aa8549e250fe45871b7bcdbf7ac8738802b73c3285dbbc9cc1.png', 'sentiment': 'positive', 'sentiment_prob': 0.7262768745422363}","{'position': 2, 'link': 'https://nationaleczema.org/blog/dermavant-101223/', 'title': 'Dermavant Announces New Positive Pruritus Data for VTAMA®(tapinarof) Cream, 1% in Adults and Children as Young as Two Years Old with Atopic Dermatitis at the EADV Congress 2023', 'source': 'National Eczema Association', 'date': 'Oct 16, 2023', 'snippet': 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'sentiment_prob': 0.916375458240509}",,,,,,,,,,['neutral'],neutral,1 NCT03607487,"{'position': 1, 'link': 'https://www.termedia.pl/Hidradenitis-suppurativa-a-new-therapeutic-approach-for-an-old-disease,7,54608,1,1.html', 'title': 'Hidradenitis suppurativa: a new therapeutic approach for an old disease', 'source': 'Termedia', 'date': 'Aug 12, 2024', 'snippet': 'Hidradenitis suppurativa (HS) is a chronic inflammatory disease \ncharacterised by recurrent painful nodules, abscesses, fistulas and \nscarring...', 'thumbnail': 'https://serpapi.com/searches/6721fcead9c3e646d94aae65/images/c2ee2697aa8a15361c0e43ae8365fb4fcef6d648872d5dd5087dc965c2876ed5.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6704685091972351}",,,,,,,,,,['negative'],negative,0 NCT00273546,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa070956', 'title': 'Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 25, 2007', 'snippet': 'A randomized phase 3 trial of the treatment of squamous-cell carcinoma of \nthe head and neck compared induction chemotherapy with docetaxel plus \ncisplatin and...', 'thumbnail': 'https://serpapi.com/searches/6721fcf511db4540a6d9534f/images/ceca477a9e984e3c3b5aecd70fb5859b1dc01b34641a77ba31c0960216e0f7e3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9047420620918274}",,,,,,,,,,['neutral'],neutral,1 NCT00114530,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1703327', 'title': 'Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma', 'source': 'The New England Journal of Medicine', 'date': 'Jan 3, 2018', 'snippet': 'Despite current therapies, diffuse cutaneous systemic sclerosis \n(scleroderma) often has a devastating outcome. We compared myeloablative...', 'thumbnail': 'https://serpapi.com/searches/6721fd2030dfc13e7b3c087d/images/e8a3ca0a1fcf0d9f8f6814acd65b0f910eb399ae21ac6062b4dbbd1124b1b2ad.png', 'sentiment': 'negative', 'sentiment_prob': 0.7006190419197083}","{'position': 2, 'link': 'https://sclerodermanews.com/news/scleroderma-gene-activity-normalizes-after-stem-cell-transplant-study/', 'title': 'Stem cell transplant normalizes scleroderma gene activity: Study', 'source': 'Scleroderma News', 'date': 'Jul 16, 2024', 'snippet': 'In the SCOT study, 75 adults with severe scleroderma were assigned to an \nautologous stem cell transplant or one year of Cytoxan infusions.', 'thumbnail': 'https://serpapi.com/searches/6721fd2030dfc13e7b3c087d/images/e8a3ca0a1fcf0d9fac9fb4f47333f8169d774e843b9330a0c03d0bb13f8bd8fd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8753800988197327}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT03072147,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1156913/full', 'title': 'Small molecule inhibitors of osteoarthritis: Current development and future perspective', 'source': 'Frontiers', 'date': 'Feb 9, 2024', 'snippet': 'Osteoarthritis (OA) is one of the common degenerative joint diseases in \nclinic. It mainly damages articular cartilage, causing pain, swelling and \nstiffness...', 'thumbnail': 'https://serpapi.com/searches/6721fd31b57db8b84ab78672/images/9d3e6c175ce209a3ac00858afbb007f134980acac1130b6f8d6250649240772d.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6938455104827881}",,,,,,,,,,['negative'],negative,0 NCT01786668,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2019/10/21/xeljanz-reduces-spinal-inflammation-one-third-patients-phase-2-trial/', 'title': 'AS Patients Reduced Spinal Inflammation with Xeljanz, Phase 2 Trial Finds', 'source': 'Ankylosing Spondylitis News', 'date': 'Oct 21, 2019', 'snippet': 'Treatment with Xeljanz (tofacitinib citrate) led to a clinically meaningful \nreduction in spinal and sacroiliac joint inflammation in approximately \none-third of...', 'thumbnail': 'https://serpapi.com/searches/6721fd4563a844c688184c8d/images/c51d9d48d0e3c2bbea296e36f14ae02cce6098fe52d6a866073e80108960fefb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6531134247779846}",,,,,,,,,,['neutral'],neutral,1 NCT01631357,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00337-x', 'title': 'Randomized, multicenter, open-label trial of autologous cytokine-induced killer cell immunotherapy plus chemotherapy for squamous non-small-cell lung cancer: NCT01631357', 'source': 'Nature', 'date': 'Oct 19, 2020', 'snippet': 'We designed this randomized, multicenter, open-label trial to further \nevaluate the clinical efficacy of CIK cell immunotherapy plus chemotherapy \nin patients...', 'thumbnail': 'https://serpapi.com/searches/6721fd6efab273f966b925d5/images/bc4a2ac5a3a075e03914943452a1938c95769d75f551814053006149bf7e44ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8522579669952393}",,,,,,,,,,['neutral'],neutral,1 NCT03914326,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/news/oral-semaglutide-cuts-mace-risk-in-patients-with-type-2-diabetes/', 'title': 'Oral Semaglutide Cuts MACE Risk in Patients With Type 2 Diabetes', 'source': 'Endocrinology Advisor', 'date': '4 days ago', 'snippet': 'Topline results were announced from a cardiovascular outcomes study \nevaluating oral semaglutide in patients with type 2 diabetes.', 'thumbnail': 'https://serpapi.com/searches/6721fd774a3fcfcebea57c52/images/9724f58436ac1cdb96362d52a5d768ad710d43f52b1d3ff43bef47a0179e8d7b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8928716778755188}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/news/novo-nordisk-plans-label-expansion-for-rybelsus-following-phase-iii-win/', 'title': 'Novo Nordisk plans label expansion for Rybelsus following Phase III win', 'source': 'Clinical Trials Arena', 'date': '1 week ago', 'snippet': 'The oral semaglutide reduced the occurrence of major adverse cardiovascular \nevents (MACE) by 14% in patients with type 2 diabetes.', 'thumbnail': 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'date': 'Feb 5, 2020', 'snippet': 'Current guidelines for smoldering multiple myeloma (SMM) recommend active \nmonitoring until the onset of multiple myeloma (MM) before...', 'thumbnail': 'https://serpapi.com/searches/6721fdfde45f339dd3e6cc38/images/69300aaeea930d83fe6bc603264464e51130863ee9fe64b99b7a849deb58f3e3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9120025038719177}",,,,,,,,,,['neutral'],neutral,1 NCT05027269,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/fda-lifts-clinical-hold-on-aviditys-lead-antibody-conjugate-therapy-trial/', 'title': 'FDA lifts clinical hold on Avidity’s lead antibody conjugate therapy trial', 'source': 'Clinical Trials Arena', 'date': '4 weeks ago', 'snippet': 'Two years after the FDA placed partial clinical hold, Avidity can resume \nresearch of del-desiran as a treatment for myotonic dystrophy type...', 'thumbnail': 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of continuous Briumvi kept MS relapse rates and disability \nprogression low, according to analyses from a trial's extension phase."", 'thumbnail': 'https://serpapi.com/searches/67220054fda26de13ee00871/images/4b85ae20176724028cd014460fa04dfd1ff54547b5c040a510ae8f8c10fc037f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5869046449661255}","{'position': 3, 'link': 'https://www.thepharmaletter.com/biotechnology/bumpy-path-forecast-for-tg-therapeutics-briumvi-in-crowded-ms-market', 'title': 'Bumpy path forecast for TG Therapeutics’ Briumvi in crowded MS market', 'source': 'The Pharma Letter', 'date': 'Jan 13, 2023', 'snippet': ""Bumpy path forecast for TG Therapeutics' Briumvi in crowded MS market. \nBiotechnology. 13 January 2023. tg-therapeutics-large."", 'thumbnail': 'https://serpapi.com/searches/67220054fda26de13ee00871/images/4b85ae2017672402bb57946889cd5717f1f6fc737f78a0e986fa14f8c5a95724.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8876432776451111}","{'position': 4, 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globally to treat it; however, that \nmight be...', 'thumbnail': 'https://serpapi.com/searches/6721fe965f9778877f212ba9/images/8c1ff296cb1bea6c09e739ed69d4c112ea38ce5804d18ea05bcffda1974cdf37.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6351245641708374}",,,,,,,,,"['negative', 'negative']",negative,0 NCT03531060,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-018-0071-3', 'title': 'Safety and tolerability of IRL790 in Parkinson’s disease with levodopa-induced dyskinesia—a phase 1b trial', 'source': 'Nature', 'date': 'Dec 6, 2018', 'snippet': 'IRL790 is a novel compound with psychomotor stabilizing properties \nprimarily targeting the dopamine D3 receptor. IRL790 is developed as an...', 'thumbnail': 'https://serpapi.com/searches/6721ff5721e77b947e9fb7bb/images/fb728df8946aae41a7c6279592040676c659eec2f32fa5325009f47b3c3deee9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8828545808792114}",,,,,,,,,,['neutral'],neutral,1 NCT02026271,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-024-01226-x', 'title': 'Immunotherapy for glioblastoma: current state, challenges, and future perspectives | Cellular & Molecular Immunology', 'source': 'Nature', 'date': '2 weeks ago', 'snippet': 'Glioblastoma (GBM) is an aggressive and lethal type of brain tumor in human \nadults. The standard of care offers minimal clinical benefit,...', 'thumbnail': 'https://serpapi.com/searches/6721ff6075f974f2da18e649/images/a18d78a54e3d0c28772c01e8a841a62b3eff879c88c604e6a6cf02e92b954f41.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7423284649848938}",,,,,,,,,,['negative'],negative,0 NCT02670551,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0165032724010309', 'title': 'Early improvement with cariprazine as a predictor of antidepressant, anxiolytic, and antimanic response in bipolar I mania and depression: A pooled post hoc analysis of randomized cariprazine trials', 'source': 'ScienceDirect.com', 'date': 'Jun 27, 2024', 'snippet': 'Early symptomatic improvement may predict treatment response in bipolar I \ndisorder. Cariprazine has demonstrated early treatment effects in bipolar \nI...', 'thumbnail': 'https://serpapi.com/searches/6721ff611a5b54176645804d/images/f75c06decfc2f5d234610ebb9aafe7d86216bb5ffef338bb702ee46a79a5cc7b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7281509637832642}",,,,,,,,,,['neutral'],neutral,1 NCT03338816,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1913147', 'title': 'Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria', 'source': 'The New England Journal of Medicine', 'date': 'Jun 10, 2020', 'snippet': 'Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with \nresultant accumulation of delta-aminolevulinic acid (ALA) and...', 'thumbnail': 'https://serpapi.com/searches/6721ff90e6862be46eca0500/images/051a87936fd6f0924bc57719e77fea5406b4cfd80158e7a06d1f4606c04596e1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8730188012123108}","{'position': 2, 'link': 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Biotechnology. 25 August 2022. \nresearch_biotech_lab_vial_big."", 'thumbnail': 'https://serpapi.com/searches/6721ffc7b6a79cce02302f02/images/2c3abc853ab46d7f37edbf075fa7bcde5a82153611f03a2ce9b6b1343e1660a5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6952041983604431}",,,,,,,,,,['neutral'],neutral,1 NCT04502693,"{'position': 1, 'link': 'https://www.contemporarypediatrics.com/view/fda-accepts-bla-for-meningococcal-abcwy-vaccine-target-action-date-set', 'title': 'FDA accepts BLA for meningococcal ABCWY vaccine, target action date set', 'source': 'Contemporary Pediatrics', 'date': 'Apr 16, 2024', 'snippet': ""The Biologics License Application (BLA) for GSK's 5-in-1 meningococcal \nABCWY (MenABCWY) vaccine candidate has been accepted for review by the FDA."", 'thumbnail': 'https://serpapi.com/searches/6721feb298876dbcee66d73d/images/2212a6f85d8afd067a81677d967de357ec4a14ca59e007b166e35e73f17f6e9e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.854534387588501}",,,,,,,,,,['neutral'],neutral,1 NCT03302234,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2020/11/25/merck-halts-phase-3-keynote-598-trial-yervoy-keytruda-combo-lung-cancer/', 'title': 'Merck Halts Phase 3 Trial on Yervoy-Keytruda Combo in Advanced Lung Cancer', 'source': 'Immuno-Oncology News', 'date': 'Nov 25, 2020', 'snippet': 'Merck is suspending its Phase 3 KEYNOTE-598 trial assessing a \nYervoy/Keytruda combo for advanced non-small cell lung cancer due to a lack \nof...', 'thumbnail': 'https://serpapi.com/searches/6721feb7c5d7695ce97cde18/images/4e26c829dab3050568696d32ec61fba8510cae1bd943ada17f566e6a4eb35e4c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5480629801750183}","{'position': 2, 'link': 'https://immuno-oncologynews.com/2021/02/08/yervoy-keytruda-combo-no-benefit-advanced-lung-cancer-keynote-598-phase-3-trial/', 'title': 'Keytruda-Yervoy Combo of No Benefit to Advanced Lung Cancer Patients', 'source': 'Immuno-Oncology News', 'date': 'Feb 8, 2021', 'snippet': 'Findings of no survival benefits and more toxicity in KEYNOTE-598 trial \nsupport Keytruda alone as first-line therapy for select NSCLC...', 'thumbnail': 'https://serpapi.com/searches/6721feb7c5d7695ce97cde18/images/4e26c829dab3050506ec5cfe9a1adfc62e8942fc65cfbde8298392219ebb8db2.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7513617277145386}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT03298867,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1910434', 'title': 'Teprotumumab for the Treatment of Active Thyroid Eye Disease', 'source': 'The New England Journal of Medicine', 'date': 'Jan 22, 2020', 'snippet': 'Teprotumumab resulted in better outcomes with respect to proptosis, \nClinical Activity Score, diplopia, and quality of life than placebo; \nserious adverse events...', 'thumbnail': 'https://serpapi.com/searches/6721fecb7c1712a3f3a2d8eb/images/579ca8e4d5c2d96ba6f3e9ea23b64abdd7a61cdedd88d6e3f2f8d7f6e4027906.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4944324493408203}","{'position': 2, 'link': 'https://www.nature.com/articles/s41433-021-01539-5', 'title': 'Teprotumumab for thyroid eye disease: early response is not required for benefit', 'source': 'Nature', 'date': 'Jun 28, 2021', 'snippet': 'In recent trials, 50% of patients treated with teprotumumab for thyroid eye \ndisease had significant improvements in proptosis at 6 weeks.', 'thumbnail': 'https://serpapi.com/searches/6721fecb7c1712a3f3a2d8eb/images/579ca8e4d5c2d96b2a680d20ffa6a5ab26827e54b8c9104bb62b66569db2f316.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5698319673538208}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04020380,"{'position': 1, 'link': 'https://sarcoidosisnews.com/news/antibiotic-azithromycin-reduces-cough-in-pulmonary-sarcoidosis-study-concludes/', 'title': 'Antibiotic Azithromycin Curbs Cough in Pulmonary Sarcoidosis, Study Concludes', 'source': 'Sarcoidosis News', 'date': 'Dec 10, 2020', 'snippet': 'Three months of treatment with the common, generic antibiotic azithromycin \nsafely reduced the number of coughs and cough severity, and improved the \nquality of...', 'thumbnail': 'https://serpapi.com/searches/6721feda4677bf466e6a05f2/images/7fb3fdb981ff814cf7a0e1117b4f60f0d5435717172208199eba1216ff72374b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8291922807693481}",,,,,,,,,,['neutral'],neutral,1 NCT04523220,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02794-7', 'title': 'Anticoagulation with osocimab in patients with kidney failure undergoing hemodialysis: a randomized phase 2 trial', 'source': 'Nature', 'date': 'Feb 16, 2024', 'snippet': 'Individuals with kidney failure undergoing hemodialysis are at elevated \nrisk for thromboembolic events. Factor (F) XI, which is in the...', 'thumbnail': 'https://serpapi.com/searches/6721fee1f9f904883975238f/images/d6c41accd1a98d98a5711f1e470066829ce616812ce908d6caba7b9c6bd6fdfb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8075672388076782}",,,,,,,,,,['neutral'],neutral,1 NCT01432353,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-019-0178-8', 'title': 'Phase I study of the anti-FcRH5 antibody-drug conjugate DFRF4539A in relapsed or refractory multiple myeloma', 'source': 'Nature', 'date': 'Feb 4, 2019', 'snippet': 'FcRH5 is a cell surface marker enriched on malignant plasma cells when \ncompared to other hematologic malignancies and normal tissues.', 'thumbnail': 'https://serpapi.com/searches/6721ff27fda26de13ee00750/images/3fa6d62841e0e15b62c528d095bfc57f2530f375eb58d292de2d4e3114d95a63.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8361889123916626}",,,,,,,,,,['neutral'],neutral,1 NCT02579226,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02185-2', 'title': 'Safety, tolerability, and pharmacokinetics of Aurora kinase B inhibitor AZD2811: a phase 1 dose-finding study in patients with advanced solid tumours | British Journal of Cancer', 'source': 'Nature', 'date': 'Mar 4, 2023', 'snippet': 'AZD2811 is a potent, selective Aurora kinase B inhibitor. 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'ibdnewstoday.com', 'date': 'Jun 24, 2019', 'snippet': ""The first patients have been dosed in two Phase 2 trials assessing the \neffects of SHR0302, Reistone's JAK1 inhibitor for inflammatory bowel..."", 'thumbnail': 'https://serpapi.com/searches/672201bf9e38e52cc8f61f93/images/39a67154ee2042a8e300c535b44acfbb467829cb7af40334be1248f9e811ba97.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9314698576927185}",,,,,,,,,,['neutral'],neutral,1 NCT01424670,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30426-0/abstract', 'title': 'Efficacy and safety of delamanid in combination with an optimised background regimen for treatment of multidrug-resistant tuberculosis: a multicentre, randomised, double-blind, placebo-controlled, parallel group phase 3 trial', 'source': 'The Lancet', 'date': 'Jan 7, 2019', 'snippet': 'Efficacy and safety of delamanid in combination with an optimised \nbackground regimen for treatment of multidrug-resistant 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'link': 'https://www.empr.com/home/news/ryzumvi-now-available-to-reverse-pharmacologically-induced-mydriasis/', 'title': 'Ryzumvi Now Available to Reverse Pharmacologically-Induced Mydriasis', 'source': 'Medical Professionals Reference', 'date': 'Apr 1, 2024', 'snippet': 'Ryzumvi is a preservative-free eye drop formulation of phentolamine \nmesylate, a nonselective alpha-1 and alpha-2 adrenergic antagonist that...', 'thumbnail': 'https://serpapi.com/searches/67220221acf7f878b6162e2d/images/205f18351f86a43185f32001af71b8a710ebae2ae9ea395a1fb44c89b79609d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8309853672981262}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04659096,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-46531-1', 'title': 'Expected and unexpected effects after systemic inhibition of Hippo transcriptional output in cancer', 'source': 'Nature', 'date': 'Mar 27, 2024', 'snippet': 'Hyperactivation of YAP/TAZ, the Hippo pathway downstream effectors, 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Fibrosis can be a significant pathology in \nmultiple organs,...', 'thumbnail': 'https://serpapi.com/searches/672202595ddfba5b347b7a6c/images/62050989f9f5cfb91ec9b77a08a0343b9d8139fd9ce17fd4435cc94dbbcd36dc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6716067790985107}",,,,,,,,,,['neutral'],neutral,1 NCT01010061,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1313984', 'title': 'Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions', 'source': 'The New England Journal of Medicine', 'date': 'Jan 8, 2014', 'snippet': 'The monoclonal anti-CD20 antibody rituximab, combined with chemotherapeutic \nagents, has been shown to prolong overall survival in physically...', 'thumbnail': 'https://serpapi.com/searches/6722027d14c31e91e4a4e73c/images/9f2e094203a81c0e0bac9e772b1b2f42ac9d46dc1d102376af20ea09eb620e77.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7021942734718323}",,,,,,,,,,['neutral'],neutral,1 NCT04659161,"{'position': 1, 'link': 'https://www.psychiatrictimes.com/view/post-hoc-analysis-explores-risk-benefit-profile-of-karxt', 'title': 'Post Hoc Analysis Explores Risk-Benefit Profile of KarXT', 'source': 'Psychiatric Times', 'date': 'May 31, 2024', 'snippet': 'A poster presented at the 2024 ASCP Annual Meeting discussed the results of \na study on the efficacy and tolerability of the investigational...', 'thumbnail': 'https://serpapi.com/searches/6722028076585765bc440e17/images/36232eae0432bd6aeb9c27d265ed0d81bda4eaf9d471e04d61766f781b016ae7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8977423906326294}","{'position': 2, 'link': 'https://www.psychiatrist.com/jcp/antipsychotic-efficacy-of-karxt-xanomeline-trospium/', 'title': 'Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study', 'source': 'Psychiatrist.com', 'date': 'May 11, 2022', 'snippet': 'KarXT provided clinically meaningful responder rates on PANSS total score \ncompared with placebo at each response threshold, providing further support \nof the...', 'thumbnail': 'https://serpapi.com/searches/6722028076585765bc440e17/images/36232eae0432bd6a54a6001a5d7e10d9e8a2dfca9ce69e3917a52715df09a5b4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8605852127075195}","{'position': 3, 'link': 'https://www.empr.com/news/cobenfy-approved-for-adult-patients-with-schizophrenia/', 'title': 'Cobenfy Approved for Adult Patients with Schizophrenia', 'source': 'Medical Professionals Reference', 'date': '1 month ago', 'snippet': 'The Food and Drug Administration (FDA) has approved Cobenfy (xanomeline and \ntrospium chloride) for the treatment of adults with schizophrenia.', 'thumbnail': 'https://serpapi.com/searches/6722028076585765bc440e17/images/36232eae0432bd6a657183bf4e1406bfb9263e6ddfac472b5d73a3eafa39f0d0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7815037369728088}","{'position': 4, 'link': 'https://www.psychiatrictimes.com/view/pharmacogenomics-sticking-to-the-evidence-base', 'title': 'Pharmacogenomics: Sticking to the Evidence Base', 'source': 'Psychiatric Times', 'date': 'May 9, 2024', 'snippet': 'John. J. Miller, MD, sat down with us at the 2024 American Psychiatric \nAssociation Annual Meeting to discuss pharmacogenomics, a topic he is very \npassionate...', 'thumbnail': 'https://serpapi.com/searches/6722028076585765bc440e17/images/36232eae0432bd6a115ab9ea7a523e56fea406a04479050d0d1ed56408b5fb28.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7020533680915833}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT05501522,"{'position': 1, 'link': 'https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00317-6/fulltext', 'title': 'Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial - eClinicalMedicine', 'source': 'The Lancet', 'date': 'Sep 7, 2023', 'snippet': 'GBP510 vaccine contains self-assembling, recombinant nanoparticles \ndisplaying SARS-CoV-2 spike receptor-binding domains.', 'thumbnail': 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'https://www.nejm.org/doi/full/10.1056/NEJMoa2111563', 'title': 'Trial of Spesolimab for Generalized Pustular Psoriasis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 22, 2021', 'snippet': 'Spesolimab, a humanized anti–interleukin-36 receptor monoclonal antibody, \nis being studied for the treatment of GPP flares.', 'thumbnail': 'https://serpapi.com/searches/67220367a5aae9204588f7e5/images/b3d16b864ec885ea07bc0329932c4556e2f0a2ff1a6a24ad0d729a5a87045f50.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9019375443458557}",,,,,,,,,,['neutral'],neutral,1 NCT02614794,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1914609', 'title': 'Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Dec 11, 2019', 'snippet': 'Patients with human epidermal growth factor receptor 2 (HER2)–positive \nmetastatic breast cancer who have disease progression after therapy...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa9a8600b8d817503e968685a3bcc08ac375d8a087cbb0364c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7983696460723877}","{'position': 2, 'link': 'https://news.cuanschutz.edu/cancer-center/tucatinib', 'title': 'Tucatinib “game changing” against stage IV HER2+ breast cancer, especially with brain metastases', 'source': 'University of Colorado Anschutz Medical Campus', 'date': 'Dec 11, 2019', 'snippet': 'Phase III clinical trial results reported today in the New England Journal \nof Medicine and presented concurrently at the San Antonio Breast...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa479d818ce72b75998571402f9cb3de7f457841801b887b90.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8076128363609314}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/real-world-analysis-of-tucatinib-triplet-yields-positive-safety-profile-in-her2-metastatic-breast-cancer', 'title': 'Real-World Analysis of Tucatinib Triplet Yields Positive Safety Profile in HER2+ Metastatic Breast Cancer', 'source': 'Cancer Network', 'date': 'Dec 8, 2022', 'snippet': 'Results from the real-world analysis of the phase 2 HER2CLIMB trial showed \na good safety profile with the tucatinib triplet regimen in...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa1131300a192d1122896aab814c359dc1b8b61453f9a1f646.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7039353847503662}","{'position': 4, 'link': 'https://www.ajmc.com/view/t-dxd-sustained-substantial-durable-clinical-activity-in-patients-with-her2-metastatic-breast-cancer', 'title': 'T-DXd Sustained Substantial, Durable Clinical Activity in Patients With HER2+ Metastatic Breast Cancer', 'source': 'AJMC', 'date': '1 month ago', 'snippet': 'According to research presented at the European Society for Medical \nOncology Congress 2024 in Barcelona, Spain, by Nancy Lin, MD,...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa93ef1f4927e69c96ea487952bf6cdcf2d40e47c7c36490ac.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.899843156337738}","{'position': 5, 'link': 'https://www.targetedonc.com/view/confronting-challenges-and-embracing-progress-in-her2-breast-cancer', 'title': 'Confronting Challenges and Embracing Progress in HER2+ Breast Cancer', 'source': 'Targeted Oncology', 'date': 'Apr 12, 2024', 'snippet': 'Yara Abdou, MD, medical oncologist at the University of North Carolina \n(UNC) in Chapel Hill, looks back on what have been the biggest...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfad5d5a706361bfe03028c66a747fde56ba6743b0fd1808a49.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9009709358215332}","{'position': 6, 'link': 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\n(capecitabine), for treating metastatic HER2-positive breast cancer in..."", 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa66ee75d24dea3f14b2205485d96140ea89140a95798ca6ef.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7427335381507874}","{'position': 8, 'link': 'https://www.targetedonc.com/view/activity-with-tucatinib-across-the-blood-brain-barrier-presents-a-vital-option-in-her2-breast', 'title': 'Activity With Tucatinib Across the Blood-Brain Barrier Presents a Vital Option in HER2+ Breast Cancer', 'source': 'Targeted Oncology', 'date': 'May 19, 2020', 'snippet': 'In an interview with Targeted Oncology, Rashmi Murthy, MD, discussed the \nfinal results from the HER2CLIMB study and the future of tucatinib...', 'thumbnail': 'https://serpapi.com/searches/6722038f9109867ea007262b/images/30278cd3cf9b5bfa783826de10752551447b7c69787ceaed6020b1da1fc3c16b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9205821752548218}",,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT03580369,"{'position': 1, 'link': 'https://www.pharmiweb.com/press-release/2024-10-23/global-drug-eruptions-treatment-market-to-reach-usd-71-billion-by-2033-growing-at-a-62-cagr', 'title': 'Global Drug Eruptions Treatment Market to Reach USD 7.1 Billion by 2033, Growing at a 6.2% CAGR', 'source': 'PharmiWeb.com', 'date': '6 days ago', 'snippet': 'Drug Eruptions Treatment MarketThe global drug eruptions treatment market \nis set to experience steady growth over the next decade,...', 'thumbnail': 'https://serpapi.com/searches/672203b571b0e8b89c48c9f9/images/6815d018c3b17219e730bb4529fc420a2fb33a7bf8cffde872159a4c33a36d4d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5003542304039001}",,,,,,,,,,['neutral'],neutral,1 NCT03766581,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-08768-y', 'title': 'Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants', 'source': 'Nature', 'date': 'Mar 25, 2022', 'snippet': 'This randomized, double-blind, placebo-controlled, multiple ascending–dose \nstudy evaluated safety, tolerability, pharmacokinetics,...', 'thumbnail': 'https://serpapi.com/searches/6722041b316650b50a5d09e8/images/b8102c7bc6dfd5cd745521d9840219ba6687f66a27786af9a89f679689cd4e3d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8481782674789429}",,,,,,,,,,['neutral'],neutral,1 NCT00137995,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-023-00889-5', 'title': 'Comparison of tisagenlecleucel with conventional treatments for relapsed/refractory diffuse large B-cell lymphomas: a retrospective external comparator study | Blood Cancer Journal', 'source': 'Nature', 'date': 'Aug 18, 2023', 'snippet': 'Only one study by Maziarz et al. to date has demonstrated improved patient \nsurvival with tisa-cel using two individual patient data (IPD) from the \nJULIET study...', 'thumbnail': 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virus', 'source': 'Nature', 'date': 'Sep 25, 2023', 'snippet': 'In this review, I will discuss the impact of RSV on human health and how \nstructure-based vaccine design set the stage for numerous RSV \ncountermeasures to...', 'thumbnail': 'https://serpapi.com/searches/6722044af60b6f4fdd4da0f6/images/448db5b452c3c066e52898337ab9245bb928fece4053d3b17fe8206255abbba1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8935171365737915}","{'position': 3, 'link': 'https://www.businesswire.com/news/home/20240723229019/en/Merck-Announces-Topline-Results-from-Phase-2b3-Trial-of-Clesrovimab-MK-1654-an-Investigational-Respiratory-Syncytial-Virus-Preventative-Monoclonal-Antibody-for-Infants', 'title': 'Merck Announces Topline Results from Phase 2b/3 Trial of Clesrovimab (MK-1654), an Investigational Respiratory Syncytial Virus Preventative Monoclonal Antibody for Infants', 'source': 'Business Wire', 'date': 'Jul 23, 2024', 'snippet': 'Merck Announces Topline Results from Phase 2b/3 Trial of Clesrovimab \n(MK-1654), an Investigational RSV Preventative Monoclonal Antibody for...', 'thumbnail': 'https://serpapi.com/searches/6722044af60b6f4fdd4da0f6/images/448db5b452c3c06600a25af6924b2dbcaafbbeb6c230d43c3b89c1a9e05147cb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9196798801422119}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02344290,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2304146', 'title': 'Pitavastatin to Prevent Cardiovascular Disease in HIV Infection', 'source': 'The New England Journal of Medicine', 'date': 'Jul 23, 2023', 'snippet': 'The risk of cardiovascular disease is increased among persons with human \nimmunodeficiency virus (HIV) infection, so data regarding primary...', 'thumbnail': 'https://serpapi.com/searches/67220470caddc31ce576aaf4/images/0493faeb1e924e7c476134613eda163703e28a2af1b4a101ed5689caf16f6ad2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5175327062606812}",,,,,,,,,,['neutral'],neutral,1 NCT03020160,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/web-based-calculator-helps-finetune-dosage-hemlibra-hemophilia-a-patients/', 'title': 'Hemophilia A Patient Care Facilitated with Hemlibra Dosing Calculator', 'source': 'Hemophilia News Today', 'date': 'May 24, 2019', 'snippet': 'A web-based dosing calculator to help physicians select the correct loading \nand maintenance dose of the treatment Hemlibra according to the body \nmeasurements.', 'thumbnail': 'https://serpapi.com/searches/67220533d0c9832b6154f06d/images/f65fdcbc5d34319309eb0bff46d48ffd53a9d98938339310f41957d57e08cef0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9187051057815552}",,,,,,,,,,['neutral'],neutral,1 NCT02025621,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1616218', 'title': 'Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery', 'source': 'The New England Journal of Medicine', 'date': 'Mar 19, 2017', 'snippet': 'In a multicenter, randomized, placebo-controlled, phase 3 trial, we \nevaluated the efficacy and safety of levosimendan in patients with a...', 'thumbnail': 'https://serpapi.com/searches/672205444e9efc409f1cf450/images/af9af50fca179041a819dc89c14f6fba0473d4fb521c21dfd6ec6b8bafc094d6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8953907489776611}",,,,,,,,,,['neutral'],neutral,1 NCT01728064,"{'position': 1, 'link': 'https://friedreichsataxianews.com/friedreichs-ataxia-experimental-treatments/epi-743-vatiquinone/', 'title': ""EPI-743 (Vatiquinone) for Friedreich's Ataxia"", 'source': ""Friedreich's Ataxia News"", 'date': 'Sep 7, 2023', 'snippet': ""EPI-743 (Vatiquinone) is being developed by BioElectron for Friedreich's \nataxia and received FDA orphan drug and fast track designations."", 'thumbnail': 'https://serpapi.com/searches/6722054d6273fbfd4ebfcd1c/images/14b88fb380f749817079451146d8397034775bc2da8fb063ccf73c9081053b6c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8560620546340942}","{'position': 2, 'link': 'https://friedreichsataxianews.com/news/fa-patients-show-improvements-epi743-phase-trial/', 'title': 'FA Patients Show Improvements with Investigational EPI-743 in Phase 2 Trial', 'source': ""Friedreich's Ataxia News"", 'date': 'Aug 2, 2018', 'snippet': ""Long-term use of EPI-743 (vatiquinone) can improve neurological function \nand prevent progression of Friedreich's ataxia, Phase 2 trial..."", 'thumbnail': 'https://serpapi.com/searches/6722054d6273fbfd4ebfcd1c/images/14b88fb380f74981ec1fbca93ec820bc6113d7839f50e23d9efd808b018a74c4.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7339364886283875}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT03164993,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-02126-1', 'title': 'Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial', 'source': 'Nature', 'date': 'Dec 8, 2022', 'snippet': 'The randomized, placebo-controlled ALICE trial (NCT03164993) evaluated the \naddition of atezolizumab (anti-PD-L1) to immune-stimulating chemotherapy in \nmTNBC.', 'thumbnail': 'https://serpapi.com/searches/6722055081bab782be64874e/images/fb5a27343744aa2860bfc4feb3ca15032c2776d5bcf0ee4067182c5c4cd8e608.png', 'sentiment': 'neutral', 'sentiment_prob': 0.905595600605011}",,,,,,,,,,['neutral'],neutral,1 NCT02451696,"{'position': 1, 'link': 'https://www.science.org/doi/10.1126/science.adj2244', 'title': 'Neurosurgery elucidates somatic mutations', 'source': 'Science | AAAS', 'date': 'Dec 21, 2023', 'snippet': 'Somatic variants are genomic alterations present in some cells of the body \nbut not in others. In contrast to inherited germline variants,...', 'thumbnail': 'https://serpapi.com/searches/67220567a3657ab8d46d0591/images/fa823c9cf35a18a98fd99b3d492ae2ab7b0cbe3e9fecfb99e6ecc1d6cb0f497c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8988147974014282}",,,,,,,,,,['neutral'],neutral,1 NCT01673867,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1507643', 'title': 'Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 27, 2015', 'snippet': 'We report the results of a randomized, open-label, international phase 3 \nstudy comparing nivolumab with docetaxel in previously treated patients \nwith advanced...', 'thumbnail': 'https://serpapi.com/searches/6722058b9fd3091aa2d92142/images/aec4ba79dfbb72aedc7a4bf70de82ccb7d101ee3e8def2abdd6b7d7895327601.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9051253795623779}","{'position': 2, 'link': 'https://www.nature.com/articles/s41698-023-00403-x', 'title': 'Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer | npj Precision Oncology', 'source': 'Nature', 'date': 'Jun 1, 2023', 'snippet': 'The tumor immune composition influences prognosis and treatment sensitivity \nin lung cancer. The presence of effective adaptive immune...', 'thumbnail': 'https://serpapi.com/searches/6722058b9fd3091aa2d92142/images/aec4ba79dfbb72aeb95f5cdf12677fe50f269d2ba6b1d10b277c0be08d6b16c9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9170801043510437}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01541215,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1903822', 'title': 'Liraglutide in Children and Adolescents with Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Apr 28, 2019', 'snippet': 'Liraglutide, at a dose of up to 1.8 mg per day (added to metformin, with or \nwithout basal insulin), was efficacious in improving glycemic control over \n52 weeks.', 'thumbnail': 'https://serpapi.com/searches/672205a2fc40bf18ede9935b/images/00254b7c4b99c0765e16d0f5f224eb2a0df5b5258b2d798fe99b227a7dd1f7f5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6073904633522034}",,,,,,,,,,['neutral'],neutral,1 NCT02422615,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.2018.78.9909', 'title': 'Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: MONALEESA-3 | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Jun 3, 2018', 'snippet': 'This phase III study evaluated ribociclib plus fulvestrant in patients with \nhormone receptor–positive/human epidermal growth factor receptor \n2–negative...', 'thumbnail': 'https://serpapi.com/searches/672205b52c566df19c3d92a9/images/70800918f8c20059af7927bdbe91e57de4c04c96f81f3552fff5f867e8aae7f6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9057517647743225}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/ribociclib-plus-fulvestrant-continued-to-improve-os-in-advanced-hr-breast-cancer-regardless-of-setting', 'title': 'Ribociclib Plus Fulvestrant Continued to Improve OS in Advanced, HR+ Breast Cancer, Regardless of Setting', 'source': 'Cancer Network', 'date': 'Jun 5, 2021', 'snippet': 'Ribociclib (Kisqali) plus fulvestrant (Faslodex) maintained significantly \nimproved overall survival (OS) rates after nearly 5 years of...', 'thumbnail': 'https://serpapi.com/searches/672205b52c566df19c3d92a9/images/70800918f8c20059766d44fa6381f86828691ab6770d6f38576c7e7fa246cda0.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5330244302749634}","{'position': 3, 'link': 'https://breastcancer-news.com/2018/07/25/fda-approves-kisqali-for-breast-cancer-in-premenopausal-perimenopausal-women/', 'title': 'FDA Approves Kisqali for Breast Cancer in Pre-, Perimenopausal Women', 'source': 'breastcancer-news.com', 'date': 'Jul 25, 2018', 'snippet': 'Kisqali (ribociclib) now can be used in combination with an aromatase \ninhibitor as first-line therapy for all women with HR-positive, \nHER2-negative advanced or...', 'thumbnail': 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'https://breastcancer-news.com/2019/10/16/kisqali-faslodex-combo-prolongs-survival-of-women-with-breast-cancer/', 'title': 'Kisqali-Faslodex Combo Prolongs Survival in Advanced Breast Cancer', 'source': 'breastcancer-news.com', 'date': 'Oct 16, 2019', 'snippet': 'Kisqali-Faslodex combo prolongs survival of women with advanced or \nmetastatic breast cancer, interim analysis of the MONALEESA-3 trial...', 'thumbnail': 'https://serpapi.com/searches/672205b52c566df19c3d92a9/images/70800918f8c2005970b8b038209f5226845164fde0164572554a5aae9a626d3f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5592573285102844}",,,,,,"['neutral', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00063713,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-0113-2', 'title': 'Advances in targeted therapy for malignant lymphoma', 'source': 'Nature', 'date': 'Mar 6, 2020', 'snippet': 'The incidence of lymphoma has gradually increased over previous decades, \nand it ranks among the ten most prevalent cancers worldwide.', 'thumbnail': 'https://serpapi.com/searches/672205babe80137f461932ab/images/60ce978491c21d87288646167e81ac2f038995032fb731581b163c336931f9d5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8373763561248779}",,,,,,,,,,['neutral'],neutral,1 NCT00133952,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332221007009', 'title': 'New progress in drugs treatment of diabetic kidney disease', 'source': 'ScienceDirect.com', 'date': 'Jul 20, 2021', 'snippet': 'In this review, we sort out the progress in the treatment of DKD in recent \nyears, the research status of some emerging drugs, and the potential drugs \nfor the...', 'thumbnail': 'https://serpapi.com/searches/672205c9f7adbfc5af9f1fb7/images/0d26985dae31ffb3361ac669e6818e71a3f9ca273dc15600aabfcc7cdd8fec0f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.900636613368988}",,,,,,,,,,['neutral'],neutral,1 NCT02966028,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-74592-x', 'title': 'A novel assay to measure calcification propensity: from laboratory to humans', 'source': 'Nature', 'date': 'Oct 16, 2020', 'snippet': 'We examined the pharmacodynamic effects of SNF472, a calcification \ninhibitor, on plasma calcium phosphate crystallization using spectrometric \nmeasurements.', 'thumbnail': 'https://serpapi.com/searches/672205e7f922f68abd6e8b9c/images/979564f5f88b027fe5c6b1658f24e3bf3d7a31bf8a2f587040a10e806e4957f6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9063605666160583}",,,,,,,,,,['neutral'],neutral,1 NCT02990338,"{'position': 1, 'link': 'https://www.onclive.com/view/isatuximab-plus-pomalidomide-and-dexamethasone-shows-meaningful-pfs-benefit-in-multiple-myeloma', 'title': 'Isatuximab Plus Pomalidomide and Dexamethasone Shows Meaningful PFS Benefit in Multiple Myeloma', 'source': 'OncLive', 'date': 'Aug 26, 2022', 'snippet': 'Isatuximab plus pomalidomide and dexamethasone elicited favorable \nprogression-free survival and proved tolerable in pretreated patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/672205ef544c49a3ab20a3a1/images/23d25abe57b552eacb76731a16a31e8a5b8125187d157a28a16b8081b5fc1fff.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7996633052825928}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/sarclisa-extends-survival-rrmm-long-term-phase-3-trial/', 'title': 'Sarclisa Extends Survival in RRMM, Long-term Phase 3 Trial Data Shows', 'source': 'Myeloma Research News', 'date': 'Mar 14, 2022', 'snippet': 'Sarclisa plus Pomalyst and dexamethasone extended survival by 6.9 months in \nrelapsed/refractory multiple myeloma patients, 3-year data show.', 'thumbnail': 'https://serpapi.com/searches/672205ef544c49a3ab20a3a1/images/23d25abe57b552eab52983632ce5cda2b7d83e037db302708fbb5fea532b2244.png', 'sentiment': 'positive', 'sentiment_prob': 0.5437084436416626}","{'position': 3, 'link': 'https://myelomaresearchnews.com/news/fda-approves-sarclisa-combo-to-treat-relapsed-or-refractory-multiple-myeloma/', 'title': 'Sarclisa Combo for Advanced Multiple Myeloma Approved by FDA', 'source': 'Myeloma Research News', 'date': 'Mar 4, 2020', 'snippet': 'The US Food and Drug Administration (FDA) has approved Sarclisa \n(isatuximab-irfc), in combination with Pomalyst (pomalidomide) and \ndexamethasone, to treat...', 'thumbnail': 'https://serpapi.com/searches/672205ef544c49a3ab20a3a1/images/23d25abe57b552ea22940aa5f39e843477815de26f4af675eeef2ba081028f21.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6747493147850037}",,,,,,,,"['positive', 'positive', 'neutral']",positive,1 NCT04056910,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-024-00646-2', 'title': 'Treatment of IDH-mutant glioma in the INDIGO era', 'source': 'Nature', 'date': 'Jul 19, 2024', 'snippet': 'The recently published INDIGO trial, demonstrating the benefit of the \nmutant IDH inhibitor vorasidenib in patients with low-grade IDH-mutant \ngliomas,...', 'thumbnail': 'https://serpapi.com/searches/672205f9e9b6912bceead42b/images/8cd86ca6fca95637e9927ac88cb1aec23b5549637f8f74d885476aeb7907a8c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7965724468231201}",,,,,,,,,,['neutral'],neutral,1 NCT02123121,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01503-7', 'title': 'The mitophagy pathway and its implications in human diseases | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Aug 16, 2023', 'snippet': 'Mitophagy serves as a cytoprotective mechanism to remove superfluous or \ndysfunctional mitochondria and maintain mitochondrial fine-tuning numbers \nto balance...', 'thumbnail': 'https://serpapi.com/searches/672205faea57e910a7c0650c/images/b7cdca4620cf80c400f1e3e523dbac0903ab256c71310785329c30ae3324683d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.925862193107605}",,,,,,,,,,['neutral'],neutral,1 NCT05590403,"{'position': 1, 'link': 'https://www.drugdiscoverytrends.com/gsk-rsv-vaccine-approval-arexvy-new-market/', 'title': 'A look at the RSV vaccine landscape as GSK wins FDA approval', 'source': 'Drug Discovery & Development', 'date': 'Oct 30, 2023', 'snippet': 'GSK (NYSE:GSK) is aiming to expand the label for its respiratory syncytial \nvirus (RSV) vaccine Arexvy, which was the first to win FDA approval.', 'thumbnail': 'https://serpapi.com/searches/67220600690121576731d512/images/b8f99b3f08e197ffe7d3b61ab3bcdfcedad1cd21f4cf3548e675b183079e13f5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7244263291358948}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20240606055012/en/US-FDA-Approves-Expanded-Age-Indication-for-GSK%E2%80%99s-AREXVY-the-First-Respiratory-Syncytial-Virus-RSV-Vaccine-for-Adults-Aged-50-59-at-Increased-Risk', 'title': 'US FDA Approves Expanded Age Indication for GSK’s AREXVY the First Respiratory Syncytial Virus (RSV) Vaccine for Adults Aged 50-59 at Increased Risk', 'source': 'Business Wire', 'date': 'Jun 7, 2024', 'snippet': 'The US Food and Drug Administration (FDA) has approved AREXVY (Respiratory \nSyncytial Virus (RSV) Vaccine, Adjuvanted) for the prevention of RSV \nlower...', 'thumbnail': 'https://serpapi.com/searches/67220600690121576731d512/images/b8f99b3f08e197ffdf9a17cd30dc70087c064e34709cd923e70f89ad000fe9d6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8796454668045044}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04419506,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2201737', 'title': 'Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'May 15, 2022', 'snippet': 'In this phase 2, double-blind, placebo-controlled trial, we investigated \nthe efficacy and safety of BI 1015550, an oral preferential inhibitor of \nthe PDE4B...', 'thumbnail': 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Phase 3 Trial Testing BI 1015550', 'source': 'Pulmonary Fibrosis News', 'date': 'Oct 28, 2022', 'snippet': 'Boehringer Ingelheim has enrolled the first patient in FIBRONEER-IPF, a \nPhase 3 clinical trial evaluating the efficacy, safety, and tolerability of \nBI 1015550.', 'thumbnail': 'https://serpapi.com/searches/672206074a4a1d50e18564aa/images/6e02eb3b6692265d6c44d134c9229fd79ab51eeac9566241b9545e7a54559275.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8812422156333923}","{'position': 4, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/oral-pde4b-inhibitor-gets-breakthrough-tx-status-for-idiopathic-pulmonary-fibrosis/', 'title': 'Oral PDE4B Inhibitor Gets Breakthrough Tx Status for Idiopathic Pulmonary Fibrosis', 'source': 'Medical Professionals Reference', 'date': 'Feb 24, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted Breakthrough Therapy \ndesignation to BI 1015550 for the treatment of idiopathic pulmonary \nfibrosis (IPF).', 'thumbnail': 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Doses 1st Patient', 'source': 'Breast Cancer News', 'date': 'Feb 7, 2020', 'snippet': 'The first patient with advanced breast cancer has been dosed in a Phase 1b \nclinical trial investigating the ability of its small molecule inhibitor, \nGMI-1359,...', 'thumbnail': 'https://serpapi.com/searches/67220628b4fe87248f8f8ce3/images/20a51c1224e357990ca211786fa19fb08ab907a73f5e8642e460ddddf2ea648e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8458389043807983}",,,,,,,,,,['neutral'],neutral,1 NCT03748186,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2021/02/04/phase-1-trial-starts-testing-ovarian-cancer-patients-with-recommended-stro-002-dose/', 'title': 'Early Trial Starts Testing Recommended STRO-002 Dose for Advanced Cancer', 'source': 'Ovarian Cancer News Today', 'date': 'Feb 4, 2021', 'snippet': 'Sutro Biopharma has dosed the first patient in the dose-expansion group of \nits Phase 1 clinical trial evaluating STRO-002 for advanced...', 'thumbnail': 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The developments of the...', 'thumbnail': 'https://serpapi.com/searches/6722062e9062f8271d862b71/images/14732bfe9b9d2804dbd8a64e375c8879027d3cd80bfda9c39097320b9291e05b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6648945212364197}","{'position': 3, 'link': 'https://ovariancancernewstoday.com/2020/05/06/stro-002-continues-to-show-promising-safety-and-anti-tumor-activity-in-advanced-ovarian-cancer-phase-1-trial-shows/', 'title': 'STRO-002 Continues to Show Promise in Advanced Ovarian Cancer, Early Trial Results Show', 'source': 'Ovarian Cancer News Today', 'date': 'May 6, 2020', 'snippet': 'Read about a Phase 1 trial showing sustained safety and anti-tumor activity \nof STRO-002 in women with advanced ovarian cancer.', 'thumbnail': 'https://serpapi.com/searches/6722062e9062f8271d862b71/images/14732bfe9b9d28045a95f243e4be515d8d6e62fe9eb43449edb5f51c5ad320d5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6907550692558289}","{'position': 4, 'link': 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Sacituzumab Govitecan for HR+ MBC', 'source': 'Targeted Oncology', 'date': 'Apr 22, 2024', 'snippet': 'During a Community Case Forum live event in partnership with The Arizona \nClinical Oncology Society, Felipe Batalini, MD, discussed the...', 'thumbnail': 'https://serpapi.com/searches/67220665aab36dd7965e3bac/images/e07116873fb480630cde02af7d989d4c669c76248aca559f40262e11225987f4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9425888657569885}","{'position': 2, 'link': 'https://www.onclive.com/view/practical-considerations-for-adc-selection-in-hr-her2--mbc', 'title': 'Practical Considerations for ADC Selection in HR+/HER2- mBC', 'source': 'OncLive', 'date': 'Aug 22, 2023', 'snippet': 'Panelists share clinical insight into how to approach treatment selection \namong ADCs in HR+/HER2- metastatic breast cancer both now and in...', 'thumbnail': 'https://serpapi.com/searches/67220665aab36dd7965e3bac/images/e07116873fb4806325fe81c9b74e5bc8723bbd075dd2d77b0b0b1431fa6b985d.jpeg', 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This study aims to...', 'thumbnail': 'https://serpapi.com/searches/6722082972f7160b741105ed/images/ce63a905c9c158f4c0be03603cb420a11b65d0f7c3124abf26a8819075ca7a9d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8230471611022949}","{'position': 2, 'link': 'https://www.researchgate.net/figure/3D-ROI-within-a-small-neuroendocrine-isthmus-pancreatic-tumor-on-CT-image-on-pancreatic_fig1_331173854', 'title': 'Figure 1. 3D ROI within a small neuroendocrine isthmus pancreatic tumor...', 'source': 'ResearchGate', 'date': 'Feb 24, 2019', 'snippet': 'To evaluate pancreatic neuroendocrine neoplasms (panNENs) grade prediction \nby means of qualitative and quantitative CT evaluation, and 3D CT-texture...', 'thumbnail': 'https://serpapi.com/searches/6722082972f7160b741105ed/images/ce63a905c9c158f407b366cc42d087be6f6b1d2756af06eb6f5e04802f2c9388.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9163271188735962}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03090191,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0264410X23012963', 'title': 'A phase 3 study evaluating the lot consistency, immunogenicity, safety, and tolerability of a Clostridioides difficile vaccine in healthy adults 65 to 85 years of age', 'source': 'ScienceDirect.com', 'date': 'Dec 7, 2023', 'snippet': 'Three doses (Months 0,1,6) of toxoid-based C difficile vaccine induced \nrobust neutralizing antibody responses and were well tolerated in healthy \nparticipants...', 'thumbnail': 'https://serpapi.com/searches/67220837c821270c41798356/images/e4c78929f958f3f44886193e6ffbdb2be7db340ed186019c085ee53973d84d10.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7878576517105103}","{'position': 2, 'link': 'https://www.pharmacytimes.com/view/managing-recurrent-c-difficile-infections-past-present-and-future', 'title': 'Managing Recurrent C difficile Infections: Past, Present, and Future', 'source': 'Pharmacy Times', 'date': 'Jan 25, 2024', 'snippet': 'The primary treatments for CDI are vancomycin (Vancocin; ANI \nPharmaceuticals), metronidazole, and fidaxomicin (Dificid; Merck); \ntreatment recurrence may occur...', 'thumbnail': 'https://serpapi.com/searches/67220837c821270c41798356/images/e4c78929f958f3f46980b73222f7b5071ad729a567c226f84f0cde4bb093f708.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8705163598060608}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04391569,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20241017642755/en/Marinus-Pharmaceuticals-Presents-Clinical-Data-From-Pivotal-Phase-3-RAISE-Trial-in-Refractory-Status-Epilepticus-at-the-Neurocritical-Care-Society-2024-Annual-Meeting', 'title': 'Marinus Pharmaceuticals Presents Clinical Data From Pivotal Phase 3 RAISE Trial in Refractory Status Epilepticus at the Neurocritical Care Society 2024 Annual Meeting', 'source': 'Business Wire', 'date': '2 weeks ago', 'snippet': 'Marinus Pharmaceuticals, Inc. (Nasdaq: MRNS), a pharmaceutical company \ndedicated to the development of innovative therapeutics to treat...', 'thumbnail': 'https://serpapi.com/searches/67220840dda9d9ba52efef75/images/34863c85aa5b84525f78b79844468286f7816fe82f17499f267c4954bca81021.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8361420035362244}","{'position': 2, 'link': 'https://www.pharmaceutical-technology.com/news/marinus-fails-to-meet-early-stopping-criteria-for-status-epilepticus-trial/', 'title': 'Marinus fails to meet early stopping criteria for status epilepticus trial', 'source': 'Pharmaceutical Technology', 'date': 'Apr 15, 2024', 'snippet': 'The future development of IV ganaxolone will be determined by results from \nthe Phase III RAISE study, expected in summer 2024.', 'thumbnail': 'https://serpapi.com/searches/67220840dda9d9ba52efef75/images/34863c85aa5b8452d56ed7e254198503ac6df4debefdbca0c753edbd778614d7.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5823642611503601}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT01206608,"{'position': 1, 'link': 'https://retractionwatch.com/2021/04/15/pharma-company-demands-retraction-damages-in-lawsuit-against-journal/', 'title': 'Pharma company demands retraction, damages in lawsuit against journal', 'source': 'Retraction Watch', 'date': 'Apr 15, 2021', 'snippet': 'A drug company that manufactures a painkiller used for surgery patients has \nsued an anesthesiology journal along with its editor and publisher.', 'thumbnail': 'https://serpapi.com/searches/6722085420e6eb9381df1f5e/images/9dc74200c4cbda893dacfd197a7cd7a2cea5b109d6b38d90d219225aa6c2f46b.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7863892912864685}",,,,,,,,,,['negative'],negative,0 NCT03964415,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/lack-of-efficacy-ends-trial-evaluating-janssens-hiv-vaccine-candidate/', 'title': 'Lack of Efficacy Ends Trial Evaluating Janssen’s HIV Vaccine Candidate', 'source': 'Medical Professionals Reference', 'date': 'Jan 18, 2023', 'snippet': 'A phase 3 trial evaluating an investigational HIV vaccine regimen for the \nprevention of HIV-1 infection will be discontinued.', 'thumbnail': 'https://serpapi.com/searches/67220856707fd32ced3b37fa/images/4cccd2dc81017335c7330b88e04f6c2f2f06f72e0225b6f9ddf6a6ae334d7783.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.666358470916748}","{'position': 2, 'link': 'https://www.idse.net/HIV-AIDS--STIs/Article/12-22/Janssen-and-Partners-Discontinue-Mosaico-HIV-Vaccine-Trial-/69229', 'title': 'Mosaico HIV Vaccine Janssen HIV Phase 3 Trial', 'source': 'Infectious Disease Special Edition', 'date': 'Jan 19, 2023', 'snippet': 'The phase 3 Mosaico HIV vaccine clinical trial was discontinued because \nevidence of efficacy was lacking, according to a statement released...', 'thumbnail': 'https://serpapi.com/searches/67220856707fd32ced3b37fa/images/4cccd2dc8101733514cfd18b7e9aae03632b144bef9a805430c8e55b34fd93ec.jpeg', 'sentiment': 'negative', 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we present final efficacy and safety results of a phase 2 basket trial \nof dabrafenib (BRAF kinase inhibitor) plus trametinib (MEK inhibitor) in \neight...', 'thumbnail': 'https://serpapi.com/searches/6722087ec4bcf586aa621835/images/a7814b00ac5091f43b30fd2d0b2bd03bfc8e04d2304e7e4493dfb4a8b3b7986b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8969771862030029}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/fda-grants-accelerated-approval-to-dabrafenib-plus-trametinib-for-braf-v600e-tumor-agnostic-indication', 'title': 'FDA Grants Accelerated Approval to Dabrafenib Plus Trametinib for BRAF V600E+ Tumor-Agnostic Indication', 'source': 'Cancer Network', 'date': 'Jun 23, 2022', 'snippet': 'Dabrafenib plus trametinib may now be used to treat patients with BRAF \nV600E–positive solid tumors who have no suitable alternative...', 'thumbnail': 'https://serpapi.com/searches/6722087ec4bcf586aa621835/images/a7814b00ac5091f497840de38621091b644b4d811da8653a3dacb2517de2f421.jpeg', 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outline the rationale for senescent cells as a \ntherapeutic target for disorders across the lifespan and discuss the most \npromising...', 'thumbnail': 'https://serpapi.com/searches/6722088548b9f7c4b1c63d1b/images/39d9ebb3dc9be84aca380b55ec4a7533f5fdcbbd1825ba0816f9f026659b51e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9145572185516357}",,,,,,,,,,['neutral'],neutral,1 NCT01366209,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1402582', 'title': 'A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'May 18, 2014', 'snippet': 'In two of three phase 3 trials, pirfenidone, an oral antifibrotic therapy, \nreduced disease progression, as measured by the decline in forced...', 'thumbnail': 'https://serpapi.com/searches/67220920ec5410d487bf9d2a/images/01b1c70ee73d1c63181cf5aa25fba41e30d1783fbc4a56bded25bd6e00b8406c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8116573095321655}","{'position': 2, 'link': 'https://lungdiseasenews.com/2015/08/03/roches-pirfenidone-esbriet-found-offer-therapeutic-benefit-ipf-clinical-practice-setting/', 'title': 'Roche’s Pirfenidone (Esbriet) Found to Offer Therapeutic Benefit For IPF in a Clinical Practice Setting', 'source': 'Lung Disease News', 'date': 'Aug 3, 2015', 'snippet': 'A new study recently published in the journal Advances in Therapy provided \nevidence of the therapeutic benefit of pirfenidone (known by the...', 'thumbnail': 'https://serpapi.com/searches/67220920ec5410d487bf9d2a/images/01b1c70ee73d1c6328bc9cba66477e8d2717bfd5e54d70b410b1f17df2337c44.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5445698499679565}","{'position': 3, 'link': 'https://www.pulmonologyadvisor.com/news/pirfenidone-may-be-effective-for-improving-exercise-capacity-dyspnea-in-idiopathic-pulmonary-fibrosis/', 'title': 'Pirfenidone May Be Effective for Improving Exercise Capacity, Dyspnea in Idiopathic Pulmonary Fibrosis', 'source': 'Pulmonology Advisor', 'date': 'Oct 10, 2018', 'snippet': 'When treated with pirfenidone, patients with idiopathic pulmonary fibrosis \nexperienced significant improvements in 6-minute walking distance...', 'thumbnail': 'https://serpapi.com/searches/67220920ec5410d487bf9d2a/images/01b1c70ee73d1c638b428e6f45192157beb41a89a7d013cd2a46f207e0a70515.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5335983633995056}","{'position': 4, 'link': 'https://pulmonaryfibrosisnews.com/news/australian-ipf-registry-identifies-characteristics-predictors-mortality-among-idiopathic-pulmonary-fibrosis-patients/', 'title': 'Australian IPF Registry Identifies Characteristics, Predictors of...', 'source': 'Pulmonary Fibrosis News', 'date': 'Jun 19, 2017', 'snippet': 'Read about an Australian report that lung function and GAP (gender, age, \nphysiology) stage are key prognostic markers for mortality in IPF.', 'thumbnail': 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'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1255611/full', 'title': 'Immunotherapy: a promising approach for glioma treatment', 'source': 'Frontiers', 'date': 'Feb 8, 2024', 'snippet': 'Gliomas are the most prevalent primary malignant brain tumors worldwide, \nwith glioblastoma (GBM) being the most common and aggressive type.', 'thumbnail': 'https://serpapi.com/searches/67220943ce1e1081fec03664/images/20f2d923e07e5de3215ebed008b44e3c02e3caf5862e448b812b1eadfb5bb339.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6341026425361633}",,,,,,,,,,['neutral'],neutral,1 NCT02519036,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1900907', 'title': 'Targeting Huntingtin Expression in Patients with Huntington’s Disease', 'source': 'The New England Journal of Medicine', 'date': 'May 6, 2019', 'snippet': 'IONIS-HTT Rx (hereafter, HTT Rx ) is an antisense oligonucleotide designed \nto inhibit HTT messenger RNA and thereby reduce concentrations of mutant \nhuntingtin.', 'thumbnail': 'https://serpapi.com/searches/6722095851d84d1f0a6f142e/images/75ff62e6f40989decca0db67d44f90850cbad9add487db023cc67859536ea53c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8518282771110535}","{'position': 2, 'link': 'https://huntingtonsdiseasenews.com/ionis-httrx-rg6042/', 'title': 'Tominersen for Huntington’s disease', 'source': ""Huntington's Disease News"", 'date': 'Jun 6, 2024', 'snippet': 'Last updated June 6, 2024, by Marisa Wexler, MS ✓ Fact-checked by Marta \nFigueiredo, PhD. How tominersen works. Administration. Clinical trials. \nSide effects...', 'thumbnail': 'https://serpapi.com/searches/6722095851d84d1f0a6f142e/images/75ff62e6f40989def2062704789453ea915191ce64e018ea5d85d1d8c51a73bd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9408097863197327}","{'position': 3, 'link': 'https://huntingtonsdiseasenews.com/news/generation-hd1-trial-fails-to-demonstrate-benefits-tominersen/', 'title': 'GENERATION HD1 Trial Fails to Show Benefits of Tominersen', 'source': ""Huntington's Disease News"", 'date': 'May 6, 2021', 'snippet': ""Treatment with tominersen failed to show evidence of clinical benefit in \nadults with Huntington's disease during the Phase 3 trial..."", 'thumbnail': 'https://serpapi.com/searches/6722095851d84d1f0a6f142e/images/75ff62e6f40989ded8b03ef9d0229b2eb9e2b185366ba9ad70474d7f2a0b714a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7655267715454102}","{'position': 4, 'link': 'https://huntingtonsdiseasenews.com/news/rg6042-potential-dmt-in-phase-3-trial-named-orphan-drug-in-japan/', 'title': 'RG6042, Potential DMT in Phase 3 Trial, Named Orphan Drug in Japan', 'source': ""Huntington's Disease News"", 'date': 'Mar 5, 2020', 'snippet': 'Japan named RG6042, designed to target all forms of the disease-causing \nmutant huntingtin protein, an orphan drug – a status also given it...', 'thumbnail': 'https://serpapi.com/searches/6722095851d84d1f0a6f142e/images/75ff62e6f40989de8f0baa0f4d58b03947ced30f5e353fc7b65ad49251941ce7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.882026195526123}",,,,,,,"['neutral', 'neutral', 'negative', 'neutral']",neutral,1 NCT04346654,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/bjh.19074', 'title': 'Immunomodulation with romiplostim as a second-line strategy in primary immune thrombocytopenia: The iROM study', 'source': 'Wiley Online Library', 'date': 'Sep 21, 2023', 'snippet': 'Thrombopoietin receptor agonists (TPO-RAs) stimulate platelet production, \nwhich might restore immunological tolerance in primary immune \nthrombocytopenia (ITP).', 'thumbnail': 'https://serpapi.com/searches/672209aef59d00190ff65ec4/images/7d8de5d6f0b6d4be47bfbc8db85e4dc543a0660362342250a4ccc04e92d982c3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7507727146148682}",,,,,,,,,,['neutral'],neutral,1 NCT00574132,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1304839', 'title': ""Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease"", 'source': 'The New England Journal of Medicine', 'date': 'Jan 23, 2014', 'snippet': ""Bapineuzumab, a humanized anti–amyloid-beta monoclonal antibody, is in \nclinical development for the treatment of Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/672209b8d9c3e646d94ab8de/images/111fc7b79204a072a55759817548523d69095a814d9ec686af843946132aa0db.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8981547355651855}",,,,,,,,,,['neutral'],neutral,1 NCT04904549,"{'position': 1, 'link': 'https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00345-0/fulltext', 'title': 'Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, multi-country study', 'source': 'The Lancet', 'date': 'Sep 12, 2023', 'snippet': 'Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with \nAS03 adjuvant in adults: a phase 3, multi-country study', 'thumbnail': 'https://serpapi.com/searches/672209bbf6aa530a196e8ebc/images/8a3776e4b941aae38e435192631a3c5f3f8783bcbe382aec9db20c4888614d35.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8498545289039612}",,,,,,,,,,['neutral'],neutral,1 NCT03829436,"{'position': 1, 'link': 'https://mesothelioma.net/bruno-bastos-md/', 'title': 'Dr. Bruno Bastos | Oncologist Mesothelioma Immunotherapy', 'source': 'Mesothelioma.net', 'date': 'Apr 23, 2024', 'snippet': 'Dr. Bruno Bastos is a medical oncologist who practices at the Miami Cancer \nInstitute at Baptist Health in Miami, Florida.', 'thumbnail': 'https://serpapi.com/searches/672209bf6a5dd3bbff20fbf0/images/2b2757b8b9cbb8a50745c7969b3ccd72c936ffd9024e9e48af1831bcdd42a416.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.930178165435791}",,,,,,,,,,['neutral'],neutral,1 NCT01710358,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1608345', 'title': 'Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis', 'source': 'The New England Journal of Medicine', 'date': 'Feb 16, 2017', 'snippet': 'Baricitinib was associated with significant clinical improvements as \ncompared with placebo and adalimumab.', 'thumbnail': 'https://serpapi.com/searches/672209d4213c87eb83468cfe/images/bbc688ac6f628ff35583eb0954cafa9f027c52d12214f464e74396c036180a76.png', 'sentiment': 'positive', 'sentiment_prob': 0.514316201210022}","{'position': 2, 'link': 'https://rheumatoidarthritisnews.com/2017/03/03/olumiant-ra-rheumatoid-arthritis-symptoms-humira-study/', 'title': 'Olumiant Improved RA Symptoms Better Than Humira, Study Finds', 'source': 'rheumatoidarthritisnews.com', 'date': 'Mar 3, 2017', 'snippet': 'Read about how Olumiant improved the clinical outcomes in patients with \nrheumatoid arthritis in comparison to Humira and placebo.', 'thumbnail': 'https://serpapi.com/searches/672209d4213c87eb83468cfe/images/bbc688ac6f628ff396d70469c86ae56b9234ade7b4907b23e53a01c256f129ae.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7494127154350281}",,,,,,,,,"['positive', 'positive']",positive,1 NCT02574455,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2028485', 'title': 'Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Apr 21, 2021', 'snippet': 'Patients with metastatic triple-negative breast cancer have a poor \nprognosis. Sacituzumab govitecan is an antibody–drug conjugate composed...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb36d96b930e75e7fc3547eca367c7b7f272f64857cdbac65f.png', 'sentiment': 'negative', 'sentiment_prob': 0.5631178617477417}","{'position': 2, 'link': 'https://www.nature.com/articles/s41523-022-00467-1', 'title': 'Safety analyses from the phase 3 ASCENT trial of sacituzumab govitecan in metastatic triple-negative breast cancer', 'source': 'Nature', 'date': 'Aug 29, 2022', 'snippet': 'Sacituzumab govitecan (SG) is an anti-Trop-2 antibody-drug conjugate with \nan SN-38 payload. In the ASCENT study, patients with metastatic...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb201f1ee96f7146215b0723f5b57efb09f4d3065573536430.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8899267315864563}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/phase-3-ascent-trial-in-metastatic-tnbc-meets-primary-end-point-of-pfs', 'title': 'Phase 3 ASCENT Trial in Metastatic TNBC Meets Primary End Point of PFS', 'source': 'Cancer Network', 'date': 'Jul 6, 2020', 'snippet': 'The phase 3 ASCENT trial designed to evaluate sacituzumab govitecan-hziy in \npatients with brain metastasis-negative,...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb49d1a590a8f17dda1b963fabeee0b14bb021a258820d52b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9164993762969971}","{'position': 4, 'link': 'https://www.targetedonc.com/view/gupta-explores-sacituzumab-govitecan-in-advanced-breast-cancer-treatment', 'title': 'Gupta Explores Sacituzumab Govitecan in Advanced Breast Cancer Treatment', 'source': 'Targeted Oncology', 'date': '5 days ago', 'snippet': 'Following discussions on ado-trastuzumab emtansine and fam-trastuzumab \nderuxtecan-nxki, Tanya Gupta, MD, discusses sacituzumab govitecan and...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb0ed4b42cc2917befd673cbc922c998564b16a16964975ca0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9038917422294617}","{'position': 5, 'link': 'https://www.nature.com/articles/s41523-022-00439-5', 'title': 'Sacituzumab govitecan as second-line treatment for metastatic triple-negative breast cancer—phase 3 ASCENT study subanalysis | npj Breast Cancer', 'source': 'Nature', 'date': 'Jun 9, 2022', 'snippet': 'Sacituzumab govitecan (SG), an antibody-drug conjugate composed of an \nanti-Trop–2 antibody coupled to SN-38 via a hydrolyzable linker, improved \noutcomes over...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38ebaa930a8b7087793849507210a94cdc245f27e0b1bcfa752b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8685733675956726}","{'position': 6, 'link': 'https://www.targetedonc.com/view/batalini-explores-role-of-ugt1a1-in-patients-treated-with-sacituzumab-govitecan-for-hr-mbc', 'title': 'Batalini Explores Role of UGT1A1 in Patients Treated With Sacituzumab Govitecan for HR+ MBC', 'source': 'Targeted Oncology', 'date': 'Apr 22, 2024', 'snippet': 'During a Community Case Forum live event in partnership with The Arizona \nClinical Oncology Society, Felipe Batalini, MD, discussed the...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb1fa8ce30c7b0df474bc17bb9c51af25dc008a56fa6f861ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9425888657569885}","{'position': 7, 'link': 'https://breastcancer-news.com/2020/04/23/trodelvy-immunomedics-approved-fda-for-heavily-pre-treated-triple-negative-breast-cancer-patients-in-us/', 'title': 'Trodelvy Approved for Heavily Pre-Treated TNBC Patients in US', 'source': 'Breast Cancer News', 'date': 'Apr 23, 2020', 'snippet': ""The US Food and Drug Administration (FDA) has approved Immunomedics' \nantibody-drug conjugate Trodelvy (sacituzumab govitecan) to treat \ntriple-negative breast..."", 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb9916f38490796c98303827aac6689d86b9ef1619251b5271.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7552862763404846}","{'position': 8, 'link': 'https://www.empr.com/home/news/trodelvy-sacituzumab-govitecan-hziy-expanded-approval-triple-negative-breast-ca/', 'title': 'FDA Grants Full Approval to Trodelvy for Triple-Negative Breast Cancer', 'source': 'Medical Professionals Reference', 'date': 'Apr 8, 2021', 'snippet': 'The Food and Drug Administration (FDA) has granted full approval to \nTrodelvy (sacituzumab govitecan-hziy) for the treatment of adult patients \nwith unresectable...', 'thumbnail': 'https://serpapi.com/searches/672209f0b28e6b3deb75f27e/images/23e4d3d601bc38eb7a4146846d3144056413491fc93fdff5b48efc7a68a6636d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8838381767272949}",,,"['negative', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00327678,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1605085', 'title': 'Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Sep 15, 2016', 'snippet': ""Treatment with rituximab has improved the outcome for patients with \nnon-Hodgkin's lymphoma. Patients with B-lineage acute lymphoblastic..."", 'thumbnail': 'https://serpapi.com/searches/67220a43f79a017c650dcaa6/images/0906797d8b552264e816520f8ad6b5f0530afe980b5f36b99000519bc1fcd92c.png', 'sentiment': 'positive', 'sentiment_prob': 0.5242841839790344}",,,,,,,,,,['positive'],positive,1 NCT00593697,"{'position': 1, 'link': 'https://www.onclive.com/view/shortened-trastuzumab-administration-does-not-improve-dfs-in-erbb2-breast-cancer', 'title': 'Shortened Trastuzumab Administration Does Not Improve DFS in ERBB2+ Breast Cancer', 'source': 'OncLive', 'date': 'Aug 29, 2024', 'snippet': 'Adjuvant trastuzumab plus concurrent chemotherapy led to inferior DFS \noutcomes when administered for 9 weeks vs 1 year in ERBB2-positive...', 'thumbnail': 'https://serpapi.com/searches/67220a56c05eb50a5fbd7e64/images/2be554b0244216fe07564d071b02c3dd6477eeca292bbda98def13b744fae981.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.786249041557312}",,,,,,,,,,['negative'],negative,0 NCT01749514,"{'position': 1, 'link': 'https://www.nature.com/articles/leu2014325', 'title': 'Myelodysplasia is in the niche: novel concepts and emerging therapies - Leukemia', 'source': 'Nature', 'date': 'Nov 14, 2014', 'snippet': ""In this review, we will discuss the scientific rationale of \n'osteohematology' as an emerging research field in MDS and outline clinical \nimplications."", 'thumbnail': 'https://serpapi.com/searches/67220ad571c62b5f89219c62/images/2913c35622506c97f8ed55e9c250dd442e5d000603457d0cae3ad69a66269085.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9074719548225403}",,,,,,,,,,['neutral'],neutral,1 NCT01863758,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/fda-approves-new-vial-strengths-for-hemophilia-a-therapy-nuwiq/', 'title': 'Hemophilia A Therapy Nuwiq to Come in New Vial Strengths in U.S.', 'source': 'Hemophilia News Today', 'date': 'Aug 28, 2017', 'snippet': ""The US Food and Drug Administration has approved new vial strengths for \nOctopharma's hemophilia A therapy Nuwiq, which means patients will need \nfewer vials per..."", 'thumbnail': 'https://serpapi.com/searches/67220b808d1473e38aba7071/images/0f7893e6374ab6998edcdfb9f940920526bafd10474815574c54610045983caf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8386752605438232}",,,,,,,,,,['neutral'],neutral,1 NCT04498910,"{'position': 1, 'link': 'https://www.mayoclinicproceedings.org/article/S0025-6196(23)00332-4/fulltext', 'title': 'Pharmacotherapies for Migraine and Translating Evidence From Bench to Bedside', 'source': 'Mayo Clinic Proceedings', 'date': 'Jan 4, 2024', 'snippet': 'Migraine is a ubiquitous neurologic disorder that afflicts more than 1 \nbillion people worldwide. Recommended therapeutic strategies include...', 'thumbnail': 'https://serpapi.com/searches/67220b88642c3145fd3ad147/images/9ba4fb32e74b9ef928c93db9155849c5bd389d9a587b1767fc263ccb91d4ad6e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7042643427848816}",,,,,,,,,,['neutral'],neutral,1 NCT00642460,"{'position': 1, 'link': 'https://juvenilearthritisnews.com/2019/09/10/tocilizumab-is-safe-and-effective-to-treat-sjia-infants-younger-than-2/', 'title': 'Tocilizumab Safe, Effective to Treat Systemic JIA Infants 2 and Younger', 'source': 'Juvenile Arthritis News', 'date': 'Sep 10, 2019', 'snippet': 'Data from a Phase 1 clinical trial demonstrated that treatment with \ntocilizumab is a safe and effective treatment for sJIA in infants...', 'thumbnail': 'https://serpapi.com/searches/67220c52d9c3e646d94abb55/images/d9cd3009586ef7b9de578eb08f99b69a3ba9959198025f7660431a7ef53ac8dc.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5793243646621704}",,,,,,,,,,['positive'],positive,1 NCT00004978,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0903175', 'title': 'Interleukin-2 Therapy in Patients with HIV Infection', 'source': 'The New England Journal of Medicine', 'date': 'Sep 8, 2017', 'snippet': 'We conducted two trials: the Subcutaneous Recombinant, Human Interleukin-2 \nin HIV-Infected Patients with Low CD4+ Counts under Active Antiretroviral \nTherapy...', 'thumbnail': 'https://serpapi.com/searches/67220c67dda9d9ba7d3b91fc/images/e762418aa1a1ab0ba5138d351861c197bac7af42297d0e3bb67c0c0c3653fb6e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9110223054885864}",,,,,,,,,,['neutral'],neutral,1 NCT02076698,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-42380-6', 'title': 'Human thalamic low-frequency oscillations correlate with expected value and outcomes during reinforcement learning', 'source': 'Nature', 'date': 'Oct 17, 2023', 'snippet': 'We found that in both the anterior thalamus (ATN) and dorsomedial thalamus \n(DMTN), low frequency oscillations (LFO, 4-12 Hz) correlated positively \nwith...', 'thumbnail': 'https://serpapi.com/searches/67220cb998d8de6796769164/images/8636d0e15fc3ec1cce7f83210e8bb2c1ccdde2c6bee6ec56c6664fbbc752dae5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8262741565704346}",,,,,,,,,,['neutral'],neutral,1 NCT01958320,"{'position': 1, 'link': 'https://www.nature.com/articles/s41372-019-0347-4', 'title': 'Comparative effectiveness of drugs used to constrict the patent ductus arteriosus: a secondary analysis of the PDA-TOLERATE trial (NCT01958320)', 'source': 'Nature', 'date': 'Mar 8, 2019', 'snippet': 'Indomethacin produced the greatest constriction (compared with spontaneous \nconstriction during Conservative management): RR (95% CI) = 3.21 \n(2.05–5.01)),...', 'thumbnail': 'https://serpapi.com/searches/67220d1708abe4e7ae1f8a0b/images/e84faf2670f52ba913b5857c31b67e52d27e1cc734295e4f82dd024d8a0fe902.png', 'sentiment': 'neutral', 'sentiment_prob': 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\ntumor-infiltrating T cells from the same patient are transplanted...', 'thumbnail': 'https://serpapi.com/searches/67220d5b361fd4c8c0469d18/images/e21ad53167bdaaf9fac6ceaf5a3e0b408b6ad985b94fcc2409766a4e50d1c881.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9120576977729797}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02465216,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-36789-2', 'title': 'Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults', 'source': 'Nature', 'date': 'Mar 6, 2023', 'snippet': 'Adjuvant-containing subunit vaccines represent a promising approach for \nprotection against tuberculosis (TB), but current candidates require...', 'thumbnail': 'https://serpapi.com/searches/67220d5dfc40bf18ede99890/images/4800930fe0ae489fec7ab716338ce742501e0d588075e564a3a5f7dfbb7f0f77.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6567094326019287}",,,,,,,,,,['neutral'],neutral,1 NCT03000452,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/fda-halts-imfinzi-combination-trials-after-unexplained-keytruda-related-deaths/', 'title': 'FDA Halts Imfinzi Combination Trials After Unexplained Keytruda-related Deaths', 'source': 'Myeloma Research News', 'date': 'Sep 8, 2017', 'snippet': ""The U.S. Food and Drug Administration (FDA) suspended a Phase 1 clinical \ntrial testing a combination of AstraZeneca's Imfinzi (durvalumab)..."", 'thumbnail': 'https://serpapi.com/searches/67220d86d169156d464f9440/images/7271c2530fab95e91fbee4e024da08655a39b9cbaf302512bc0c6c1e49496b7c.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5682772994041443}",,,,,,,,,,['negative'],negative,0 NCT04056689,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/phase-2b-3-trials-planned-oral-biib122-dnl151-slowing-parkinsons-progression/', 'title': '2 Trials to Test Oral BIIB122/DNL151 in Slowing Parkinson’s Progression', 'source': ""Parkinson's News Today"", 'date': 'Jan 13, 2022', 'snippet': 'Biogen and Denali Therapeutics are planning to launch two late-stage \nclinical trials to further evaluate the potential of their...', 'thumbnail': 'https://serpapi.com/searches/67220dbdee677f6cfefc8a5d/images/0fd0d60d94def3e132340a6612e650f7ad63d998a7a57b5c88c33a2e14585f81.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8970906734466553}",,,,,,,,,,['neutral'],neutral,1 NCT01211262,"{'position': 1, 'link': 'https://immuno-oncologynews.com/imcgp100/', 'title': 'IMCgp100', 'source': 'Immuno-Oncology News', 'date': 'Dec 21, 2017', 'snippet': 'Read about the immune-oncology therapy IMCgp100, which Immunocore is \ndeveloping as a treatment for cancers of the skin and eyes.', 'thumbnail': 'https://serpapi.com/searches/67220e055c7cb930cf00ca9b/images/2e8065064c26eded43ed466646cde49cc66feb778f3fdaf90bb3f75a67af57ec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8750774264335632}",,,,,,,,,,['neutral'],neutral,1 NCT02899988,"{'position': 1, 'link': 'https://www.dermatologyadvisor.com/news/mirikizumab-safe-efficacious-for-treating-plaque-psoriasis-in-phase-2-study/', 'title': 'Mirikizumab Safe, Efficacious for Treating Plaque Psoriasis in Phase 2 Study', 'source': 'Dermatology Advisor', 'date': 'Mar 21, 2019', 'snippet': 'Phase 2 study results showed that mirikizumab-treated patients had \nsignificantly higher efficacy compared to placebo, with comparable safety...', 'thumbnail': 'https://serpapi.com/searches/67220e0ca54d7ea54c992529/images/a90f7701e5be5963ba340024febed6141ec26a4d53e4d03cf94319ef2c9816fe.png', 'sentiment': 'positive', 'sentiment_prob': 0.635246753692627}",,,,,,,,,,['positive'],positive,1 NCT01747798,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2016/10/10/membrane-fluidity-influences-sensitivity-of-ovarian-cancer-cell-lines-to-auranofin/', 'title': 'Increasing Cell Membrane Fluidity May Enhance Ovarian Cancer Drug', 'source': 'Ovarian Cancer News Today', 'date': 'Oct 10, 2016', 'snippet': 'Cell membrane fluidity may determine ovarian cancer response to the \nanti-rheumatic drug Ridaura (auranofin) currently in trials for epithelial \novarian cancer,...', 'thumbnail': 'https://serpapi.com/searches/67220e325ed3caf6d6de987c/images/9747233e13228880f736e5c6d5e3ad8fba01a1560977ad1bdb02ec31fec4354b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8460758924484253}",,,,,,,,,,['neutral'],neutral,1 NCT06040372,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/rhythm-expands-obesity-portfolio-with-phase-ii-weight-loss-drug-for-100m/', 'title': 'Rhythm expands obesity portfolio with Phase II weight loss drug for $100m', 'source': 'Clinical Trials Arena', 'date': 'Jan 5, 2024', 'snippet': ""Rhythm to acquire global rights for South Korean LG Chem's oral obesity \ndrug LB54640 for $100m in cash and equity."", 'thumbnail': 'https://serpapi.com/searches/67220e36b9ab865cfec0d0de/images/195504f020fe41d3d91cf7b1ec4d58e41c786be6e2ea32e4bef1990a84c574a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8068321943283081}",,,,,,,,,,['neutral'],neutral,1 NCT02996305,"{'position': 1, 'link': 'https://angelmansyndromenews.com/news/final-trial-data-support-ovid-decision-stop-ov101-clinical/', 'title': 'Trial data support Ovid’s decision to stop its OV101 program in 2021', 'source': 'angelmansyndromenews.com', 'date': 'Aug 23, 2023', 'snippet': ""Final trial results have now been published that support Ovid Therapeutics' \ndecision to stop clinical testing of OV101 for Angelman..."", 'thumbnail': 'https://serpapi.com/searches/67220e585f9778874e15c901/images/918ea8bf92853b660e85647c02ff427c3493d63871b3b9e4197e87e98edeacd2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8800973892211914}","{'position': 2, 'link': 'https://angelmansyndromenews.com/news/ovid-to-add-adolescents-to-phase-2-trial-of-its-angelman-syndrome-therapy-ov101/', 'title': ""Ovid's Angelman Therapy Trial Will Be Broadened to Include Adolescents"", 'source': 'Angelman Syndrome News', 'date': 'Dec 12, 2017', 'snippet': ""Read about Ovid's decision to broaden the Phase 2 clinical trial of its \nAngelman syndrome therapy OV101 to include adolescents as well as..."", 'thumbnail': 'https://serpapi.com/searches/67220e585f9778874e15c901/images/918ea8bf92853b66c4732965813712283fbd4d46e5df5b1d1115148f28c630f1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8533443808555603}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03414034,"{'position': 1, 'link': 'https://prostatecancernewstoday.com/2020/02/19/onvansertib-extends-responses-to-zytiga-mcrpc-patients-phase-2-data/', 'title': 'mCRPC Patient Responses to Zytiga Better with Onvansertib, New Trial Data Show', 'source': 'Prostate Cancer News Today', 'date': 'Feb 19, 2020', 'snippet': 'A potential treatment, onvansertib, helped to overcome resistance to Zytiga \nin men with metastatic CRPC and rising PSA levels,...', 'thumbnail': 'https://serpapi.com/searches/67220e607c1712a3f3a2e5c5/images/160ac76f346a964669e554fcbb2b5cfc9fab74019758ade8ee4b37a30a5ffba3.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6121103167533875}",,,,,,,,,,['positive'],positive,1 NCT03822468,"{'position': 1, 'link': 'https://www.onclive.com/view/recent-data-on-adjuvant-therapies-in-hr-her2--breast-cancer', 'title': 'Recent Data on Adjuvant Therapies in HR+/HER2- Breast Cancer', 'source': 'OncLive', 'date': 'Jul 11, 2023', 'snippet': 'Experts on HR+/HER2- breast cancer review data updates on adjuvant \ntherapies from the 2023 ASCO Annual Meeting.', 'thumbnail': 'https://serpapi.com/searches/67220e67cb33d011be84a3c5/images/b21eab510ee231a743c649a5f630d38c617bf4d0e49ee02ed0282340797b0921.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9471691250801086}",,,,,,,,,,['neutral'],neutral,1 NCT03178864,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/STROKEAHA.123.044113', 'title': 'Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis', 'source': 'American Heart Association Journals', 'date': 'Sep 7, 2023', 'snippet': 'A randomized controlled feasibility trial comparing anticoagulation with \nrivaroxaban to standard-of-care in symptomatic cerebral venous thrombosis.', 'thumbnail': 'https://serpapi.com/searches/67220e76237938d086ab92c3/images/a9a238a3cf936d5a7501e3e0043c5e46252fc1395e34567d75fbee135d8fa77c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.879463255405426}",,,,,,,,,,['neutral'],neutral,1 NCT03531957,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-023-00992-4', 'title': 'The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment', 'source': 'Nature', 'date': 'Mar 16, 2023', 'snippet': 'Atopic dermatitis (AD) is the most common inflammatory skin disease, and it \nis considered a complex and heterogeneous condition.', 'thumbnail': 'https://serpapi.com/searches/67220e8e7a12fd124142e61b/images/258249bc2c201b68b66f7a4fa24cb3332dee7413d141d9557b811ab9a96668d5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7401643991470337}",,,,,,,,,,['neutral'],neutral,1 NCT01354691,"{'position': 1, 'link': 'https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-018-0299-8', 'title': 'Advances in developing novel therapeutic strategies for Alzheimer’s disease', 'source': 'Molecular Neurodegeneration', 'date': 'Dec 12, 2018', 'snippet': 'Here, we summarize current strategies and new trends of AD drug \ndevelopment, including pre-clinical and clinical trials that target \ndifferent aspects of...', 'thumbnail': 'https://serpapi.com/searches/67220eb2f79a017c2d030bfb/images/8d2df9eaaa2c2c5a0217b2c9f997ac390d132aa8ba79780ea70423e340b28fbc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8732640743255615}",,,,,,,,,,['neutral'],neutral,1 NCT04983264,"{'position': 1, 'link': 'https://sicklecellanemianews.com/osivelotor-for-sickle-cell-disease/', 'title': 'Osivelotor for sickle cell disease', 'source': 'Sickle Cell Disease News', 'date': 'May 29, 2024', 'snippet': 'Last updated May 29, 2024, by Lindsey Shapiro, PhD ✓ Fact-checked by Joana \nCarvalho, PhD. How osivelotor works. Administration. Clinical trials.', 'thumbnail': 'https://serpapi.com/searches/67220ed5690bb92396ca4cac/images/0a366ccf500b8299324ae66d1a82e9b00ad2d5e10ebcaf9b64e45dace2106a2d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9294475317001343}","{'position': 2, 'link': 'https://sicklecellanemianews.com/news/phase-1-scd-trial-supporting-gbt601-next-gen-therapy-oxbryta/', 'title': 'Phase 1 Trial Supporting GBT601 as Next-gen Therapy to Oxbryta', 'source': 'Sickle Cell Disease News', 'date': 'May 24, 2022', 'snippet': ""Daily doses of GBT601, Global Blood Therapeutics's oral sickle cell disease \ntherapy, were well tolerated and signaled efficacy in 6..."", 'thumbnail': 'https://serpapi.com/searches/67220ed5690bb92396ca4cac/images/0a366ccf500b829920dab618021ef9014895ad1aba6bd3842f7c88dd0d161be5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6596790552139282}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04027439,"{'position': 1, 'link': 'https://copdnewstoday.com/news/veronas-dry-powder-inhaler-ensifentrine-safe-and-effective-for-copd-in-phase-2-trial/', 'title': 'Ensifentrine Dry Powder Inhaler Safe, Effective for COPD in Phase 2 Trial', 'source': 'COPD News Today', 'date': 'Aug 9, 2019', 'snippet': 'Additional results of a Phase 2 trial demonstrate that a dry powder inhaler \nformulation of ensifentrine is safe and effective in moderate to...', 'thumbnail': 'https://serpapi.com/searches/67220ee58d1473e353fb5eba/images/e2547bfb91e9d9d9b6bef33bc8247d110ea4c4f23c9161b4dc85712ec8c63db7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5965437889099121}",,,,,,,,,,['positive'],positive,1 NCT02566655,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/cpr.12956', 'title': 'Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis', 'source': 'Wiley Online Library', 'date': 'Nov 18, 2020', 'snippet': 'Osteoporosis occurs when the orchestrated balance between bone formation by \nosteoblasts and bone destruction by osteoclasts breaks down,...', 'thumbnail': 'https://serpapi.com/searches/67220f1972e5c4745ca77260/images/2b99c6cc77742e35d9a33e06805f39f45590add09bf15b3b8fdedb7735273ea8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.802518367767334}",,,,,,,,,,['neutral'],neutral,1 NCT05103332,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2024/03/05/2840321/0/en/Roche-and-Alnylam-report-positive-topline-results-from-the-Phase-II-KARDIA-2-study-in-people-with-hypertension-demonstrating-clinically-significant-blood-pressure-reductions-with-z.html', 'title': 'Roche and Alnylam report positive topline results from the Phase II KARDIA-2 study in people with hypertension, demonstrating clinically significant blood pressure reductions with zilebesiran when added to standard of care', 'source': 'GlobeNewswire', 'date': 'Mar 5, 2024', 'snippet': 'KARDIA-2 study met its primary endpoint, demonstrating clinically \nsignificant systolic blood pressure reductions in each treatment arm at...', 'thumbnail': 'https://serpapi.com/searches/67220f282da1575f5eaf4c91/images/cf45b252213a718d27ad1e94dbd951755dba9b9a855788c8e3ca5d205c7e5f8e.png', 'sentiment': 'positive', 'sentiment_prob': 0.5929137468338013}",,,,,,,,,,['positive'],positive,1 NCT03132636,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2021/02/12/fda-approves-libtayo-first-immunotherapy-advanced-basal-cell-carcinoma/', 'title': 'FDA Approves Libtayo, 1st Immunotherapy for Advanced Basal Cell Carcinoma', 'source': 'Immuno-Oncology News', 'date': 'Feb 12, 2021', 'snippet': 'The U.S. Food and Drug Administration (FDA) has approved Libtayo \n(cemiplimab-rwlc), making it the first immunotherapy for people with...', 'thumbnail': 'https://serpapi.com/searches/67220f3c3c944b515f584aeb/images/2832314aa02e0f175ad0bc6fd99f12566ec7253d30d7b803046a72a1c3212b81.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5599238872528076}",,,,,,,,,,['neutral'],neutral,1 NCT02674152,"{'position': 1, 'link': 'https://www.researchgate.net/publication/384902278_Comprehensive_biomarker_and_modeling_approach_to_support_dose_finding_for_BI_836880_a_VEGFAng-2_inhibitor', 'title': '(PDF) Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor', 'source': 'ResearchGate', 'date': '2 weeks ago', 'snippet': 'PDF | Background BI 836880 is a humanized bispecific nanobody® that binds \nto and blocks vascular endothelial growth factor (VEGF) and...', 'thumbnail': 'https://serpapi.com/searches/67220f6bbd7cf0d69d201d4b/images/77eac7661d7809f53955ba89916054f755fc49b7397ccb565534068282166ca8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.89641934633255}",,,,,,,,,,['neutral'],neutral,1 NCT03005782,"{'position': 1, 'link': 'http://www.msn.com/en-us/health/other/esmo-2024-regeneron-s-melanoma-combo-therapy-benefit-continues-beyond-two-years/ar-AA1qFEHe?apiversion=v2&noservercache=1&domshim=1&renderwebcomponents=1&wcseo=1&batchservertelemetry=1&noservertelemetry=1', 'title': 'ESMO 2024: Regeneron’s melanoma combo therapy benefit continues beyond two years', 'source': 'MSN', 'date': '1 month ago', 'snippet': 'The company presented longer-term data from the Phase I trial (NCT03005782) \nat the European Society for Medical Oncology (ESMO) Annual Meeting from 13 \nto 17...', 'thumbnail': 'https://serpapi.com/searches/67220f8f360f4efda11a981e/images/d1469916ad9bd751e3d0a721d5c452db64d79b49aebb9db2b3fd89c196aa4c88.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6508203148841858}","{'position': 2, 'link': 'https://www.onclive.com/view/fianlimab-cemiplimab-demonstrates-persistent-activity-in-advanced-melanoma-independent-of-lag-3-and-pd-l1-status', 'title': 'Fianlimab/Cemiplimab Demonstrates Persistent Activity in Advanced Melanoma, Independent of LAG-3 and PD-L1 Status', 'source': 'OncLive', 'date': '1 month ago', 'snippet': 'Fianlimab combined with cemiplimab-rwlc (Libtayo) demonstrated persistent \nand significant clinical activity in patients with advanced melanoma, \nirrespective of...', 'thumbnail': 'https://serpapi.com/searches/67220f8f360f4efda11a981e/images/d1469916ad9bd751b624032cab5c485f15b34e887a344dbbefcacae268bffd14.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8469321727752686}","{'position': 3, 'link': 'https://www.onclive.com/view/fianlimab-plus-cemiplimab-yields-early-efficacy-signs-in-pretreated-advanced-ccrcc', 'title': 'Fianlimab Plus Cemiplimab Yields Early Efficacy Signs in Pretreated Advanced ccRCC', 'source': 'OncLive', 'date': 'Jul 12, 2024', 'snippet': 'Treatment with the combination of fianlimab and cemiplimab-rwlc (Libtayo) \nwas well tolerated and led to durable responses in heavily pretreated \npatients.', 'thumbnail': 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'https://www.nature.com/articles/s41375-021-01265-7', 'title': 'Current challenges and unmet medical needs in myelodysplastic syndromes', 'source': 'Nature', 'date': 'May 28, 2021', 'snippet': 'Myelodysplastic syndromes (MDS) represent a heterogeneous group of myeloid \nneoplasms that are characterized by ineffective hematopoiesis,...', 'thumbnail': 'https://serpapi.com/searches/6722103bf3cbfaeee3c3a6c0/images/95b1417bcd7d3485eb2b8ff0b37aa3d379bb7e3b27cf9994ddc6279f2ce0f5f0.png', 'sentiment': 'negative', 'sentiment_prob': 0.678302526473999}",,,,,,,,,,['negative'],negative,0 NCT01933802,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/03/10/stem-cell-therapy-msc-np-ease-inflammatory-activity-brain-cells/', 'title': 'Stem cell therapy MSC-NP can ease inflammatory activity in brain cells', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 10, 2023', 'snippet': 'MSC-NP, a form of stem cell therapy in early clinical trials for \nprogressive MS, can 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Learn more about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/672210d517b10e7c50371c43/images/32bbf26832662d51a3a647556ab368e7d7e389ea291471b15eee4f8cc6f9a951.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9069978594779968}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2020/12/15/fda-approves-shorter-infusion-time-ocrevus-therapy-ms/', 'title': 'FDA Approves Shorter Infusion Time for MS Therapy Ocrevus', 'source': 'Multiple Sclerosis News Today', 'date': 'Dec 15, 2020', 'snippet': 'The U.S. Food and Drug Administration approved a shorter infusion time of \nOcrevus (ocrelizumab) for people with relapsing or primary...', 'thumbnail': 'https://serpapi.com/searches/672210d517b10e7c50371c43/images/32bbf26832662d5173daf3982a4391366bc8d81ef98d7f8068206fde7f8e2165.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6980234384536743}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00382889,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa063861', 'title': 'Rescue Use of Beclomethasone and Albuterol in a Single Inhaler for Mild Asthma', 'source': 'The New England Journal of Medicine', 'date': 'May 17, 2007', 'snippet': 'Treatment guidelines recommend the regular use of inhaled corticosteroids \nfor patients with mild persistent asthma.', 'thumbnail': 'https://serpapi.com/searches/672210d724296a3c4a74d60d/images/218c54ece62511157a34358e779ade3b7017372b5d53251f1c472ed1b0926d68.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8787112236022949}",,,,,,,,,,['neutral'],neutral,1 NCT03237845,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1811090', 'title': 'Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine', 'source': 'The New England Journal of Medicine', 'date': 'Jul 10, 2019', 'snippet': 'Calcitonin gene–related peptide receptor has been implicated in the \npathogenesis of migraine. Rimegepant is an orally administered,...', 'thumbnail': 'https://serpapi.com/searches/672210f872f7160bb0106df8/images/4f054f695354bcead15fef04b68c11e5808b521ad027981c86ade8c042e42230.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8599758148193359}",,,,,,,,,,['neutral'],neutral,1 NCT04379869,"{'position': 1, 'link': 'https://praderwillinews.com/news/fda-oks-neuren-pharmaceuticals-trial-nnz-2591-pws-children/', 'title': 'FDA Green Lights Phase 2 Trial of NNZ-2591 in Children With PWS |...', 'source': 'Prader-Willi Syndrome News', 'date': 'Jan 27, 2023', 'snippet': 'Neuren Pharmaceuticals will test its therapeutic candidate NNZ-2591 in \nchildren with Prader-Willi syndrome (PWS) in a new Phase 2 clinical trial.', 'thumbnail': 'https://serpapi.com/searches/672211234e9efc40cad5add2/images/b205b6d153b54d9e2f33c05f4735b6f9f3e439ba37b8f557d644b8ea3036469d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8675135374069214}","{'position': 2, 'link': 'https://praderwillinews.com/news/nnz-2591-phase-2-trial-children-with-pws-recruiting-us/', 'title': 'NNZ-2591 Phase 2 trial of children with PWS is recruiting in US |...', 'source': 'Prader-Willi Syndrome News', 'date': 'Jul 6, 2023', 'snippet': 'Neuren Pharmaceuticals has opened the first site for a U.S.-based Phase 2 \nclinical trial of its investigational therapy NNZ-2591 in children...', 'thumbnail': 'https://serpapi.com/searches/672211234e9efc40cad5add2/images/b205b6d153b54d9ebda203eac14cef2c69294147c5242c23282ef90cae1ffe42.png', 'sentiment': 'neutral', 'sentiment_prob': 0.895076334476471}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04669028,"{'position': 1, 'link': 'https://www.globenewswire.com/fr/news-release/2023/06/26/2694368/0/en/index.html', 'title': 'BioVie Presents Data Highlighting Role of Insulin', 'source': 'GlobeNewswire', 'date': 'Jun 26, 2023', 'snippet': 'Baseline Data from Phase 3 Trial of NE3107 Presented as Poster at the \nAmerican Diabetes Association Annual Meeting...', 'thumbnail': 'https://serpapi.com/searches/67221159fab273f966b9360f/images/354373fb57db6a5ac5498976d97d2bbb1b477724ddf07edee17f4e1e270c2f04.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.896338701248169}",,,,,,,,,,['neutral'],neutral,1 NCT01426880,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/os-and-efs-improved-with-neoadjuvant-chemotherapy-carboplatin-for-locally-advanced-tnbc', 'title': 'OS and EFS Improved With Neoadjuvant Chemotherapy/Carboplatin for Locally Advanced TNBC', 'source': 'Cancer Network', 'date': 'Dec 10, 2022', 'snippet': 'Patients with operable, locally advanced triple-negative breast cancer \nexperienced notable improvements in survival following treatment with...', 'thumbnail': 'https://serpapi.com/searches/6722116fee468296a0065d0a/images/795f5bdb2ebeca7f2cadb9a7eec26fb6f87a2cbd6cdb2207c8f86ca57a503429.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5052809119224548}",,,,,,,,,,['positive'],positive,1 NCT04209543,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/features/2023-menopause-society-annual-meeting-highlights-vasomotor-symptoms-treatment/', 'title': '2023 Menopause Society Annual Meeting Highlights Vasomotor Symptoms Treatment', 'source': 'Endocrinology Advisor', 'date': 'Oct 13, 2023', 'snippet': 'At the North American Menopause Society 2023 Annual Meeting from September \n27 to 30 in Philadelphia, Pennsylvania, many studies focused on...', 'thumbnail': 'https://serpapi.com/searches/672211c7b691a77af4145f00/images/7786a7ce1b983e7298e180218d21ca4226d822c6afbcea2306654e5bbe40d1fa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9407566785812378}",,,,,,,,,,['neutral'],neutral,1 NCT00829166,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1209124', 'title': 'Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 1, 2012', 'snippet': 'Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate incorporating \nthe human epidermal growth factor receptor 2 (HER2)–targeted...', 'thumbnail': 'https://serpapi.com/searches/672211d530dfc13e4da29472/images/070f263b51d05c605e7c5a614ab8a71318a11d93cf94f6b4cc5eefa0e42b6d20.png', 'sentiment': 'neutral', 'sentiment_prob': 0.882633626461029}",,,,,,,,,,['neutral'],neutral,1 NCT01213407,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-019-0149-x', 'title': 'Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors', 'source': 'Nature', 'date': 'Jan 16, 2020', 'snippet': 'Glioblastoma is the most prevalent and aggressive brain cancer. With a \nmedian overall survival of ~15–20 months under standard therapy,...', 'thumbnail': 'https://serpapi.com/searches/6722123d81bab782be6491bd/images/6afe82ae92eae88b91472d01c2f42377aa4444748a9176ca56db1a9dd7cffae6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.49266043305397034}",,,,,,,,,,['neutral'],neutral,1 NCT00935623,"{'position': 1, 'link': 'https://www.nature.com/articles/nri2902', 'title': 'Experimental human challenge infections can accelerate clinical malaria vaccine development', 'source': 'Nature', 'date': 'Dec 23, 2010', 'snippet': 'These authors put forward their view that the information obtained from \nexperimental human malaria infections justifies the minimal...', 'thumbnail': 'https://serpapi.com/searches/67221296f963e7b1d30997c6/images/29f5b04927310995f73719d2bdf34e1922b5a0613fc1817b37a40c04f5b55f38.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8248225450515747}",,,,,,,,,,['neutral'],neutral,1 NCT03691623,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2108903', 'title': 'EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge', 'source': 'The New England Journal of Medicine', 'date': 'Feb 16, 2022', 'snippet': 'In a two-part, phase 2a, randomized, double-blind, placebo-controlled \nchallenge trial, we assigned participants who had been inoculated with...', 'thumbnail': 'https://serpapi.com/searches/672212bc4e9efc40cad5af16/images/418180a46e22c478f2f90daeaee027c16956a48ea49b7265907c513d3ff675e2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.899833619594574}",,,,,,,,,,['neutral'],neutral,1 NCT02492711,"{'position': 1, 'link': 'https://breastcancer-news.com/2020/12/21/margenza-approved-fda-pretreated-her2-positive-breast-cancer/', 'title': 'Margenza Approved in US for Pretreated HER2-positive Breast Cancer', 'source': 'Breast Cancer News', 'date': 'Dec 21, 2020', 'snippet': ""The FDA has approved MacroGenics' Margenza, in combination with \nchemotherapy, to treat adults with metastatic HER2-positive breast cancer."", 'thumbnail': 'https://serpapi.com/searches/672212dc30dfc13e7b3c1a93/images/66555a380cbe3711d76ed3c48237eff3c26f2b046b2edb14237e6ba3137c223e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7703570127487183}",,,,,,,,,,['neutral'],neutral,1 NCT04579250,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-021-01660-8', 'title': 'Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial', 'source': 'Nature', 'date': 'Feb 3, 2022', 'snippet': 'Currently, licensed seasonal influenza vaccines display variable vaccine \neffectiveness, and there remains a need for novel vaccine platforms...', 'thumbnail': 'https://serpapi.com/searches/672213a189055e8ea6cbc7e4/images/bb2da977e8746c5bcd932c0d56eedea0335fee8dad34df77ec39ff0f0349b2a2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8805010914802551}","{'position': 2, 'link': 'https://www.nature.com/articles/s41541-024-00959-0', 'title': 'Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine', 'source': 'Nature', 'date': '1 month ago', 'snippet': 'The relative conservation of the influenza hemagglutinin (HA) stem compared \nto that of the immunodominant HA head makes the HA stem an...', 'thumbnail': 'https://serpapi.com/searches/672213a189055e8ea6cbc7e4/images/bb2da977e8746c5b416470e7e13021a1a7ad543c30492723ced224459c2bbbdc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9192789793014526}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04657315,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2023.1139359/full', 'title': 'Mesenchymal stem cell therapy for neurological disorders: The light or the dark side of the force?', 'source': 'Frontiers', 'date': 'Jun 27, 2024', 'snippet': 'Neurological disorders are recognized as major causes of death and \ndisability worldwide. Because of this, they represent one of the largest \npublic health...', 'thumbnail': 'https://serpapi.com/searches/672213bf8f2bc25a1c97fa78/images/16382a4c8c8024c2535e73fb5b7a6929671aa5b7ef5739e67f07c4741196b828.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5713104009628296}",,,,,,,,,,['negative'],negative,0 NCT03160521,"{'position': 1, 'link': 'https://www.nature.com/articles/s41537-020-00127-y', 'title': 'in schizophrenic patients with an acute exacerbation', 'source': 'Nature', 'date': 'Nov 25, 2020', 'snippet': 'Risperidone ISM provided rapid and progressive reduction of symptoms in \npatients with acutely exacerbated schizophrenia without need of oral \nrisperidone...', 'thumbnail': 'https://serpapi.com/searches/6722131bbe1497c4b66ffd86/images/2514dff39f8961a085658e3767311cc83a31e634bd2b748964d074a662e720a2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7882256507873535}",,,,,,,,,,['neutral'],neutral,1 NCT00474630,"{'position': 1, 'link': 'https://www.nature.com/articles/s41366-018-0302-z', 'title': 'Psychiatric adverse events and effects on mood with prolonged-release naltrexone/bupropion combination therapy: a pooled analysis', 'source': 'Nature', 'date': 'Jan 21, 2019', 'snippet': 'Anxiety and sleep disorder-related PAEs were more frequent with NB versus \nplacebo but were mostly mild to moderate and generally occurred early.', 'thumbnail': 'https://serpapi.com/searches/6722132f21b01bb4cf0b9fc7/images/9727fde8949cd412671e2123a404523d75fe088f5adf6fc53a29ea4499287260.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6952958106994629}",,,,,,,,,,['neutral'],neutral,1 NCT03070782,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1905239', 'title': 'Lipoprotein(a) Reduction in Persons with Cardiovascular Disease', 'source': 'The New England Journal of Medicine', 'date': 'Jan 1, 2020', 'snippet': 'Lipoprotein(a) levels are genetically determined and, when elevated, are a \nrisk factor for cardiovascular disease and aortic stenosis.', 'thumbnail': 'https://serpapi.com/searches/672213389e38e52c96d8b8df/images/c599d193b9ab02998972a29f070cc29fc64176d44d66bbbe251485157380a3e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6087671518325806}",,,,,,,,,,['neutral'],neutral,1 NCT03944460,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/pri-002-oral-candidate-alzheimers-disease-safe-phase-1-trial/', 'title': ""PRI-002, Oral Candidate for Alzheimer's, Found Safe in Phase 1 Trial"", 'source': ""Alzheimer's News Today"", 'date': 'May 22, 2019', 'snippet': ""Alzheimer's oral therapy candidate PRI-002 has proven safe for human use in \nan early stage Phase 1 clinical trial, ensuring further testing..."", 'thumbnail': 'https://serpapi.com/searches/67221367f922f68a8717b6c8/images/cb93d25499146e489efbb67109d40e02dba2dfebde98b628fbab44f67985abfa.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6251877546310425}",,,,,,,,,,['positive'],positive,1 NCT02837575,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/vical-halts-development-of-hsv-2-vaccine-after-phase-ii-failure/', 'title': 'Vical Halts Development of HSV-2 Vaccine after Phase II Failure', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Jun 11, 2018', 'snippet': 'The HSV-2 vaccine missed its primary endpoint in the Phase II study of \nannualized lesion recurrence rate.', 'thumbnail': 'https://serpapi.com/searches/672213682a48821b6e0a63b9/images/05bffbe7d2f72be08d37ed35a906e158bd0d61af1a20c37eb69f7de029bcf499.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7711883783340454}",,,,,,,,,,['negative'],negative,0 NCT03350191,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-73815-5', 'title': 'Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes', 'source': 'Nature', 'date': 'Oct 7, 2020', 'snippet': 'In this study we investigated the target occupancy of the dual agonist \nSAR425899 at the GLP1R in pancreas and GCGR in liver by Positron Emission \nTomography/...', 'thumbnail': 'https://serpapi.com/searches/6722137dd19f15fb979b5d92/images/b94e2477d1502bc13ce5fd39880a5fec8b24279872ec11b0930f7e6397566ca2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9031040072441101}",,,,,,,,,,['neutral'],neutral,1 NCT02798406,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02347-y', 'title': 'Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial', 'source': 'Nature', 'date': 'May 15, 2023', 'snippet': 'Immune-mediated anti-tumoral responses, elicited by oncolytic viruses and \naugmented with checkpoint inhibition, may be an effective...', 'thumbnail': 'https://serpapi.com/searches/672213e2a54d7ea585ded7ea/images/dcaa21c5d8588b6868ea755167773387e94f0a5b9d60525f24aa4aab6fd1847c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.740546464920044}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.953410/full', 'title': 'Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements', 'source': 'Frontiers', 'date': 'Feb 15, 2024', 'snippet': 'Oncolytic viruses (OVs) have been gaining attention in the pharmaceutical \nindustry as a novel immunotherapeutic and therapeutic adjuvant due to \ntheir...', 'thumbnail': 'https://serpapi.com/searches/672213e2a54d7ea585ded7ea/images/dcaa21c5d8588b682bdf6cb0495265f79f6817a36a06513510d9be42c34c4af2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7581920623779297}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04926701,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/phase-2-trial-etd001-airway-mucus-obstruction-cf-planned/', 'title': 'Phase 2 trial of ETD001, for CF airway mucus obstruction, planned', 'source': 'Cystic Fibrosis News Today', 'date': 'Jun 17, 2024', 'snippet': 'ETD001, an inhaled therapy for mucus clearance, showed safety and efficacy \nat low dose in sheep, and a study in CF patients may soon open.', 'thumbnail': 'https://serpapi.com/searches/672213ff6de1e44657d96b75/images/d9fe3088b707d1e5d8dd75e2d275b708bc0a3d03ec5aca40b42fea5b00454f99.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6532422304153442}",,,,,,,,,,['neutral'],neutral,1 NCT03874897,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01800-8', 'title': 'Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results', 'source': 'Nature', 'date': 'May 9, 2022', 'snippet': 'Despite success in hematologic malignancies, the treatment landscape of \nchimeric antigen receptor (CAR) T cell therapy for solid tumors...', 'thumbnail': 'https://serpapi.com/searches/67221414a5d70237f1e01f51/images/dbbf342000e3abf2aefa352c131c51b3afd27481d5b854afab1e1c35dcfcdaa5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6915398836135864}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/carsgen-announces-enrollment-completion-in-china-gcgej-pivotal-phase-ii-clinical-trial-of-the-first-in-class-claudin18-2-car-t-satri-cel-302225000.html', 'title': 'CARsgen Announces Enrollment Completion in China GC/GEJ Pivotal Phase II Clinical Trial of the First-in-class Claudin18.2 CAR T (Satri-cel)', 'source': 'PR Newswire', 'date': 'Aug 19, 2024', 'snippet': 'This study is an open-label, multicenter, randomized clinical trial in \nChina evaluating the efficacy and safety of satri-cel in subjects with \nClaudin18.2-...', 'thumbnail': 'https://serpapi.com/searches/67221414a5d70237f1e01f51/images/dbbf342000e3abf24a68b1d9e5b648ec38cbcb4149461bf3352c8747f788ecde.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8776533603668213}","{'position': 3, 'link': 'https://www.prnewswire.com/news-releases/carsgen-initiates-phase-2-clinical-trial-for-cldn18-2-car-t-cell-product-ct041-in-the-us-301828211.html', 'title': 'CARsgen Initiates Phase 2 Clinical Trial for CLDN18.2 CAR T-cell Product CT041 in the U.S.', 'source': 'PR Newswire', 'date': 'May 18, 2023', 'snippet': 'PRNewswire/ -- CARsgen Therapeutics Holdings Limited (Stock Code: 2171.HK), \na company focused on innovative CAR T-cell therapies for the...', 'thumbnail': 'https://serpapi.com/searches/67221414a5d70237f1e01f51/images/dbbf342000e3abf2eb38158841eb66219dda082f54b34a408346d4aec4ccb861.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8880912661552429}","{'position': 4, 'link': 'https://www.asiaone.com/business-wires/carsgen-presents-updated-results-satri-cel-nature-medicine-and-2024-asco', 'title': 'CARsgen Presents Updated Results on Satri-cel in Nature Medicine and at 2024 ASCO, Business Wires News', 'source': 'AsiaOne', 'date': '1 week ago', 'snippet': 'SHANGHAI, June 4, 2024 /PRNewswire/ -- CARsgen Therapeutics Holdings \nLimited (Stock Code: 2171.HK), a company focused on innovative CAR...', 'thumbnail': 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'source': 'OncLive', 'date': '1 month ago', 'snippet': 'Pyrotinib paired with metronomic vinorelbine was safe and displayed \nefficacy in HER2-positive advanced breast cancer after prior...', 'thumbnail': 'https://serpapi.com/searches/672214301adaf494051ce6be/images/7205ddcca07a565a9c6565861be78861e09449b42b45acce17f739175cf826ea.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5048511624336243}",,,,,,,,,,['positive'],positive,1 NCT02348632,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/how-does-solriamfetol-treatment-for-osa-and-narcolepsy-affect-body-weight/', 'title': 'How Does Solriamfetol Treatment for OSA and Narcolepsy Affect Body Weight?', 'source': 'Pulmonology Advisor', 'date': 'Sep 1, 2022', 'snippet': 'Solriamfetol treatment for patients with obstructive sleep apnea (OSA) or \nnarcolepsy is associated with a decrease in body weight in a dose-related \nmanner.', 'thumbnail': 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How fitusiran works. Administration. Clinical trials. Side \neffects...', 'thumbnail': 'https://serpapi.com/searches/67221452ec5410d4be7cb17d/images/3459770cdea20d657e5b949183dcd5c54e6664fdfd7374a75c229fcfa87f79ae.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9302834868431091}",,,,,,,,,,['neutral'],neutral,1 NCT00084396,"{'position': 1, 'link': 'https://www.nature.com/articles/ncomms12498', 'title': 'Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers', 'source': 'Nature', 'date': 'Aug 9, 2016', 'snippet': 'Resistance to oestrogen-deprivation therapy is common in \noestrogen-receptor-positive (ER+) breast cancer. To better understand the...', 'thumbnail': 'https://serpapi.com/searches/6722145374f0a452ea2b5aa4/images/df9389a4cee83472eb74e0edc860efc0c455c42a8940568fcdf15fb3e77baf8f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.638504683971405}",,,,,,,,,,['neutral'],neutral,1 NCT02375698,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-27029-6', 'title': 'A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients', 'source': 'Nature', 'date': 'Nov 22, 2021', 'snippet': 'We show the first clinical data that H56:IC31 vaccination is safe and \nimmunogenic in tuberculosis patients, supporting further studies of \nH56:IC31 as a host-...', 'thumbnail': 'https://serpapi.com/searches/672214a75ed3caf6a16af5f5/images/d752b913d3d38548eceb8b39c569f657746de368f3e551a35f85dda880685e65.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6584312915802002}",,,,,,,,,,['neutral'],neutral,1 NCT03399604,"{'position': 1, 'link': 'https://pulmonaryhypertensionnews.com/news/open-label-trial-yutrepia-ild-enrolls-first-participant/', 'title': 'Open-label clinical trial of Yutrepia for PH-ILD enrolls 1st participant', 'source': 'Pulmonary Hypertension News', 'date': 'Jan 8, 2024', 'snippet': ""The first patient has entered ASCENT, a clinical study of Liquidia's \nYutrepia, an inhaled dry powder formulation of treprostinil for PH-ILD."", 'thumbnail': 'https://serpapi.com/searches/672214c38d1473e38aba783c/images/6afc786ff67a5b1f840efb20f013a772cf111732e8e49311f83b30b270aa5148.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9160255789756775}","{'position': 2, 'link': 'https://pulmonaryhypertensionnews.com/news/pah-patients-prefer-yutrepia-over-tyvaso-inspire-study/', 'title': 'PAH Patients Prefer Yutrepia Over Tyvaso in INSPIRE Study |...', 'source': 'Pulmonary Hypertension News', 'date': 'Aug 3, 2022', 'snippet': 'Yutrepia, an inhaled form of treprostinil, was preferred for the treatment \nof pulmonary arterial hypertension by patients in the INSPIRE...', 'thumbnail': 'https://serpapi.com/searches/672214c38d1473e38aba783c/images/6afc786ff67a5b1fc9d33a89a3403c41e699a076c43534dc0e20546f426c8b28.png', 'sentiment': 'neutral', 'sentiment_prob': 0.887389063835144}","{'position': 3, 'link': 'https://pulmonaryhypertensionnews.com/news/fda-delays-decision-yutrepia-treat-ph-ild/', 'title': 'FDA delays decision on extending Yutrepia to treat PH-ILD', 'source': 'Pulmonary Hypertension News', 'date': 'Jan 26, 2024', 'snippet': ""The FDA is delaying its decision to extend Yutrepia, Liquidia's inhaled dry \npowder formulation of treprostinil, to treat people with PH-ILD."", 'thumbnail': 'https://serpapi.com/searches/672214c38d1473e38aba783c/images/6afc786ff67a5b1f9c7398dafdb8465da0644ff53d959c9439833d9defc1b053.png', 'sentiment': 'negative', 'sentiment_prob': 0.5138409733772278}","{'position': 4, 'link': 'https://pulmonaryhypertensionnews.com/news/fda-approval-decision-yutrepia-liquida-ph-ild-expected-january/', 'title': 'Approval decision on Yutrepia for PH-ILD expected in January |...', 'source': 'Pulmonary Hypertension News', 'date': 'Sep 27, 2023', 'snippet': 'The US Food and Drug Administration (FDA) has agreed to review an \napplication from Liquidia that seeks to extend the approval of Yutrepia.', 'thumbnail': 'https://serpapi.com/searches/672214c38d1473e38aba783c/images/6afc786ff67a5b1f73052116aa331bdee56ea8caf3933ed3e85aba52bc89dca6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9383014440536499}",,,,,,,"['neutral', 'neutral', 'negative', 'neutral']",neutral,1 NCT05865886,"{'position': 1, 'link': 'https://www.boehringer-ingelheim.com/human-health/lung-diseases/phase-ii-trials-patients-bronchiectasis', 'title': 'Phase II trials for patients with bronchiectasis', 'source': 'Boehringer Ingelheim', 'date': 'Jun 29, 2023', 'snippet': 'Bronchiectasis is a chronically progressive pulmonary disease. Boehringer \nIngelheim investigates a potential new treatment option in two Phase II \ntrials.', 'thumbnail': 'https://serpapi.com/searches/672214efbe324f55320fa276/images/4a49c722fd97a982a220cdb52be1b55d1e44d49a9480bb05115579f10da2413f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9052193760871887}",,,,,,,,,,['neutral'],neutral,1 NCT03196297,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/novo-nordisk-pauses-three-clinical-trials-of-concizumab-due-to-safety-concerns/', 'title': 'Safety Concerns Put 3 Hemophilia Trials, Testing Concizumab, on Hold', 'source': 'Hemophilia News Today', 'date': 'Mar 18, 2020', 'snippet': 'Novo Nordisk has paused three clinical trials evaluating concizumab, its \nexperimental treatment candidate for hemophilia A and B, due to safety \nconcerns.', 'thumbnail': 'https://serpapi.com/searches/672214f411db45407348a9a1/images/741d80a932a04b19d0c9e5b00d024e6b59876954a23f73ad7e22424288cefce0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5402668714523315}",,,,,,,,,,['neutral'],neutral,1 NCT00887224,"{'position': 1, 'link': 'https://www.psychiatrist.com/pcc/efficacy-desvenlafaxine-mgd-versus-placebo-long-term/', 'title': 'Efficacy of Desvenlafaxine 50 mg/d Versus Placebo in the Long-Term Treatment of Major Depressive Disorder: A Randomized, Double-Blind Trial', 'source': 'Psychiatrist.com', 'date': 'Aug 27, 2015', 'snippet': 'Patrice Boyer, MD, PhD; Cécile Vialet, MSc; Eunhee Hwang, PhD; and Karen A. \nTourian, MD. Published: August 27, 2015. Efficacy of Desvenlafaxine 50 \nmg/d...', 'thumbnail': 'https://serpapi.com/searches/6722151fc7d4a1acec2d0958/images/0b18424c19d8b5592f3d2cd611a857ed72c46f2ee428dbab93eca8d634dc7845.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9115458130836487}",,,,,,,,,,['neutral'],neutral,1 NCT02664558,"{'position': 1, 'link': 'https://lungdiseasenews.com/2018/01/19/ubenimex-development-treat-pulmonary-arterial-hypertension-ends/', 'title': 'Ubenimex Development to Treat Pulmonary Arterial Hypertension Ends', 'source': 'Lung Disease News', 'date': 'Jan 19, 2018', 'snippet': ""Eiger BioPharmaceuticals' ubenimex failed to show improvement in pulmonary \nvascular resistance or exercise capacity in the Phase 2 LIBERTY..."", 'thumbnail': 'https://serpapi.com/searches/672215a75c7cb9309d9708d1/images/9ecfd1e23a76a534304d2e56f5ebee86d48c37244fe8f9798ff6ac92d68b5f06.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6212904453277588}",,,,,,,,,,['negative'],negative,0 NCT02496897,"{'position': 1, 'link': 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\nimmunodeficiency virus type 1 (HIV-1) acquisition is unclear.', 'thumbnail': 'https://serpapi.com/searches/67221620f93388203ee950f8/images/ac588359dd8affc0b764546873ba8daa760a162bb10335179de2469a3f26ed83.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.771469235420227}",,,,,,,,,,['neutral'],neutral,1 NCT04225260,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20241020496709/en/ASDS-2024-New-Phase-III-READY-4-Data-Demonstrate-Long-Term-Safety-and-Efficacy-of-Galderma%E2%80%99s-RelabotulinumtoxinA-Relfydess%E2%84%A2', 'title': 'ASDS 2024: New Phase III READY-4 Data Demonstrate Long-Term Safety and Efficacy of Galderma’s RelabotulinumtoxinA (Relfydess', 'source': 'Business Wire', 'date': '1 week ago', 'snippet': 'Galderma today announced new phase III data from the READY-4 clinical \ntrial, demonstrating the long-term safety of RelabotulinumtoxinA...', 'thumbnail': 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'https://cysticfibrosisnewstoday.com/news/arct-032-inhaled-cf-treatment-showing-safety-phase-1-trial/', 'title': 'ARCT-032, therapy for all with CF, showing safety in Phase 1 trial', 'source': 'Cystic Fibrosis News Today', 'date': 'Jun 12, 2024', 'snippet': 'Early signs of efficacy also were seen in 4 patients given ARCT-032, a \nmessenger RNA therapy allowing healthy CFTR production in lung cells.', 'thumbnail': 'https://serpapi.com/searches/6722168f93bb57f524e16700/images/1819434e1916cdba7e56cb2eff6277081e7b6a07ec87e78d03b398831fe3141b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7940552234649658}","{'position': 2, 'link': 'https://cysticfibrosisnewstoday.com/news/fda-orphan-drug-status-awarded-inhaled-cf-therapy-arct-032/', 'title': 'FDA orphan drug status awarded to inhaled CF therapy ARCT-032', 'source': 'Cystic Fibrosis News Today', 'date': 'Nov 28, 2023', 'snippet': ""The U.S. Food and Drug Administration has granted orphan drug status to \nArcturus' ARCT-032, an inhaled treatment for cystic fibrosis."", 'thumbnail': 'https://serpapi.com/searches/6722168f93bb57f524e16700/images/1819434e1916cdba3674792c6d023e74d5d5bf62fe226021c77575222868a6b4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8929421305656433}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02130557,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-022-01589-y', 'title': 'Bosutinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia: final results from the BFORE trial', 'source': 'Nature', 'date': 'May 28, 2022', 'snippet': 'This analysis from the multicenter, open-label, phase 3 BFORE trial reports \nefficacy and safety of bosutinib in patients with newly...', 'thumbnail': 'https://serpapi.com/searches/672216e5e8735a1451f2facd/images/dbe65edd175871afe3e528992ac87e6285c84bfe58faa4a95684810628042278.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9095726013183594}",,,,,,,,,,['neutral'],neutral,1 NCT02795676,"{'position': 1, 'link': 'https://fabrydiseasenews.com/news/prx-102-shows-safety-efficacy-similar-fabrazyme-top-line-balance-trial/', 'title': 'PRX-102 Shows Safety, Efficacy Similar to Fabrazyme in Phase 3 Trial', 'source': 'Fabry Disease News', 'date': 'Apr 29, 2022', 'snippet': 'Top-line data from Phase 3 BALANCE trial found 2 years of PRX-102 treatment \nsimilar to Fabrazyme in adults with Fabry and kidney disease.', 'thumbnail': 'https://serpapi.com/searches/6722173b11db4540a6d968dd/images/7d48fc2dbcf24afb1005084c0a33ba4aa2b25e99a6e44da8717aaf4cec4f1d05.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7387609481811523}","{'position': 2, 'link': 'https://fabrydiseasenews.com/news/fabry-disease-therapy-prx-102-now-elfabrio-wins-fda-approval/', 'title': 'Fabry disease therapy PRX-102, now Elfabrio, wins FDA approval |...', 'source': 'Fabry Disease News', 'date': 'May 10, 2023', 'snippet': ""PRX-102, now Elfabrio, won the U.S. Food and Drug Administration's approval \nas an intravenous infusion for adults with Fabry disease ."", 'thumbnail': 'https://serpapi.com/searches/6722173b11db4540a6d968dd/images/7d48fc2dbcf24afb7330455ccd4be917ff680e8f5d6302bbf8eee60574226da0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7576220631599426}","{'position': 3, 'link': 'https://fabrydiseasenews.com/news/elfabrio-effective-fabrazyme-kidney-decline-trial/', 'title': 'Elfabrio as effective as Fabrazyme for Fabry with kidney decline: Trial', 'source': 'Fabry Disease News', 'date': 'Dec 15, 2023', 'snippet': 'Elfabrio (pegunigalsidase alfa) is as safe and effective as Fabrazyme \n(agalsidase beta) and can prevent kidney decline in adults with Fabry \ndisease over two...', 'thumbnail': 'https://serpapi.com/searches/6722173b11db4540a6d968dd/images/7d48fc2dbcf24afb6541845dcfb6dcdb3da11883a6fe7aa8f54818689598f887.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5244313478469849}","{'position': 4, 'link': 'https://fabrydiseasenews.com/news/europe-approval-prx-102-plant-based-ert-adults-requested/', 'title': 'PRX-102, Potential Fabry Plant-based ERT, Up for Approval in Europe', 'source': 'Fabry Disease News', 'date': 'Mar 4, 2022', 'snippet': 'Protalix and Chiesi have applied to the European Medicines Agency for \nPRX-102 (pegunigalsidase alfa) to be approved for adults with Fabry.', 'thumbnail': 'https://serpapi.com/searches/6722173b11db4540a6d968dd/images/7d48fc2dbcf24afbe2eafde842332825448bc5a205c9b2ab1dbf92748c92d337.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8462085723876953}","{'position': 5, 'link': 'https://fabrydiseasenews.com/news/elfabrio-soon-available-fabry-patients-england-low-no-cost/', 'title': 'Elfabrio soon available to Fabry patients in England at low or no cost', 'source': 'Fabry Disease News', 'date': 'Sep 15, 2023', 'snippet': 'Elfabrio was approved in the U.K. as a long-term enzyme replacement therapy \nin adults with Fabry disease in August.', 'thumbnail': 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'https://www.empr.com/home/news/severe-burn-therapy-nexobrid-gets-fda-approval/', 'title': 'Severe Burn Therapy NexoBrid Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Jan 3, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved NexoBrid \n(anacaulase-bcdb) for eschar removal in adults with deep partial thickness \nand/or full thickness...', 'thumbnail': 'https://serpapi.com/searches/6722179d2a48821b6e0a6730/images/0b1fa972f4ca6057bd2710d0e3c0da5687465173ea547990304b337b44571b44.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6989240646362305}","{'position': 2, 'link': 'https://www.empr.com/home/news/nexobrid-now-available-for-treatment-of-severe-thermal-burns/', 'title': 'NexoBrid Now Available for Treatment of Severe Thermal Burns', 'source': 'Medical Professionals Reference', 'date': 'Sep 21, 2023', 'snippet': 'NexoBrid (anacaulase-bcdb) is now available for eschar removal in adults \nwith deep partial thickness and/or full thickness thermal burns.', 'thumbnail': 'https://serpapi.com/searches/6722179d2a48821b6e0a6730/images/0b1fa972f4ca6057dc7ac666377af4608a8b536d1d25c72d5fbb12b6cbfd6266.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8987787961959839}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01654731,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1714519', 'title': 'A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis', 'source': 'The New England Journal of Medicine', 'date': 'Jun 6, 2018', 'snippet': 'Patients with primary biliary cholangitis who have an inadequate response \nto therapy with ursodeoxycholic acid are at high risk for disease...', 'thumbnail': 'https://serpapi.com/searches/672217d9fc183d1a7918f773/images/4713b0ea2948bf8ddf522286b2097a7bbaa176b492fb4852868813aa68574828.png', 'sentiment': 'negative', 'sentiment_prob': 0.6679105162620544}",,,,,,,,,,['negative'],negative,0 NCT04501666,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/galderma-unveils-positive-results-for-prurigo-nodularis-treatment/', 'title': 'Galderma unveils positive results for prurigo nodularis treatment', 'source': 'Clinical Trials Arena', 'date': 'Jul 4, 2023', 'snippet': 'Nemolizumab could soon be used to help alleviate itching arising from \nprurigo nodularis, following the latest Phase III data unveiled by Galderma.', 'thumbnail': 'https://serpapi.com/searches/672217e22c566df19c3da05f/images/8b24e4227fdd1b172661a2fdcbf1800473e2273a18b3d74acbebea18e8f849d4.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7919019460678101}",,,,,,,,,,['positive'],positive,1 NCT02252042,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31999-8/fulltext', 'title': 'Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study', 'source': 'The Lancet', 'date': 'Nov 30, 2018', 'snippet': 'There are few effective treatment options for patients with recurrent or \nmetastatic head-and-neck squamous cell carcinoma.', 'thumbnail': 'https://serpapi.com/searches/672217ea577da59cf36d0ba7/images/444155c177439c4acdbf51964b9661c9c262ec63054d5866d3fe64efb3a6bc8d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5495750308036804}",,,,,,,,,,['neutral'],neutral,1 NCT04615923,"{'position': 1, 'link': 'https://alsnewstoday.com/news/pridopidine-shows-some-potential-in-healey-trial-but-misses-main-goal/', 'title': 'Pridopidine fails primary endpoint but improves speech, early functional decline', 'source': 'ALS News Today', 'date': 'Mar 1, 2023', 'snippet': 'Pridopidine failed to meet its primary endpoint of improved physical \nfunction in HEALEY ALS trial, but improved speech in specific patients.', 'thumbnail': 'https://serpapi.com/searches/672218091397bae56dcc67cc/images/29cb760eb95f811dbdc22d9e7e611efa6b5502fb0ed591fb9bdfc842ea387728.png', 'sentiment': 'negative', 'sentiment_prob': 0.7390066385269165}","{'position': 2, 'link': 'https://alsnewstoday.com/news/phase-3-clinical-trial-pridopidine-als-likely-this-year/', 'title': 'Phase 3 trial of oral pridopidine in treating ALS likely this year', 'source': 'ALS News Today', 'date': 'Jan 29, 2024', 'snippet': 'A Phase 2 HEALEY study tied pridopidine to slower progression and better \nrespiration and speech, particularly with early,...', 'thumbnail': 'https://serpapi.com/searches/672218091397bae56dcc67cc/images/29cb760eb95f811d3be9b080280909b695e2a10e9a4eb56178c586006b56e127.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8719426393508911}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT03520036,"{'position': 1, 'link': 'https://porphyrianews.com/news/mt-7117-eases-sunlight-sensitivity-epp-xlp-patients-phase-2-trial/', 'title': 'MT-7117 found to ease sunlight sensitivity for EPP, XLP patients |...', 'source': 'Porphyria News', 'date': 'Apr 19, 2023', 'snippet': 'The oral therapy MT-7117 was found to ease sunlight sensitivity and improve \nlife quality for porphyria patients in a Phase 2 trial.', 'thumbnail': 'https://serpapi.com/searches/67221853d169156d464f9d1e/images/586acdf8cd5dc178d390d81ce6e87051447273ba93763049cf56793e2715b442.png', 'sentiment': 'positive', 'sentiment_prob': 0.5625188946723938}","{'position': 2, 'link': 'https://porphyrianews.com/phase-3-trial-mt-7117-for-epp-xlp-porphyrias/', 'title': 'MT-7117 Poised for Phase 3 Trial in Two Types of Porphyrias', 'source': 'Porphyria News', 'date': 'May 29, 2020', 'snippet': ""A Phase 3 clinical trial of Mitsubishi Tanabe's investigational therapy \nMT-7117 (dersimelagon) for people with erythropoietic protoporphyria..."", 'thumbnail': 'https://serpapi.com/searches/67221853d169156d464f9d1e/images/586acdf8cd5dc1781b8c7c8a12409f857f2f26319a1eaf43b64a29274c099a6e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8879155516624451}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02546531,"{'position': 1, 'link': 'https://www.researchgate.net/figure/FAK-inhibitors-with-anti-tumor-activity-in-preclinical-studies-and-clinical-trials_tbl1_336934468', 'title': 'FAK inhibitors with anti-tumor activity in preclinical studies and clinical trials.', 'source': 'ResearchGate', 'date': 'Nov 2, 2019', 'snippet': 'Small-cell lung cancer (SCLC) represents 15% of all lung cancers and it is \nclinically the most aggressive type, being characterized by a tendency for \nearly...', 'thumbnail': 'https://serpapi.com/searches/6722189e544c49a379e027bc/images/45a2d53b1346717d950e87cc2687b2593651ab73ec6a306be5840a615c16dbcb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6451858282089233}",,,,,,,,,,['neutral'],neutral,1 NCT04514367,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/news/aan2023-huntingtons-therapy-anx005-stabilizes-functional-capacity-trial/', 'title': 'AAN2023: ANX005 stabilizes functional capacity in Phase 2a trial', 'source': ""Huntington's Disease News"", 'date': 'May 9, 2023', 'snippet': ""ANX005 stabilized or improved functional status for early Huntington's \ndisease patients in a Phase 2a trial."", 'thumbnail': 'https://serpapi.com/searches/672218af24296a3c10e5d5d0/images/f111c3b9a19b8daadc091c9ce4d57e7607d5aee1e6c7ebbd1cc4516c0794e880.png', 'sentiment': 'positive', 'sentiment_prob': 0.4970383048057556}",,,,,,,,,,['positive'],positive,1 NCT00197041,"{'position': 1, 'link': 'https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02466-2', 'title': 'Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children', 'source': 'BMC Medicine', 'date': 'Aug 25, 2022', 'snippet': 'RTS,S is the first malaria vaccine recommended for implementation among \nyoung children at risk. However, vaccine efficacy is modest and...', 'thumbnail': 'https://serpapi.com/searches/672218be5a461a4de7e0e00d/images/fec4b9a8ba294dac3c571e3f2063820bfbe174dc28a603235815693d9e587f26.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8192456960678101}",,,,,,,,,,['neutral'],neutral,1 NCT02831231,"{'position': 1, 'link': 'https://www.nature.com/articles/s41537-022-00320-1', 'title': 'Safety and tolerability of KarXT (xanomeline–trospium) in a phase 2, randomized, double-blind, placebo-controlled study in patients with schizophrenia', 'source': 'Nature', 'date': 'Dec 3, 2022', 'snippet': 'KarXT combines xanomeline, an M1/M4 preferring muscarinic agonist with no \ndirect D2 receptor antagonism, with the peripherally restricted...', 'thumbnail': 'https://serpapi.com/searches/672218dc93bb57f4ee1a6e1f/images/6e93ed3c286c3260dcb6d121647cbf8c681a5095ee859377269fc95ca6864832.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8456377983093262}",,,,,,,,,,['neutral'],neutral,1 NCT00753545,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0271-y', 'title': 'Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy', 'source': 'Nature', 'date': 'Oct 24, 2018', 'snippet': 'In Study 19, maintenance monotherapy with olaparib significantly prolonged \nprogression-free survival vs placebo in patients with...', 'thumbnail': 'https://serpapi.com/searches/672218ded771bdbb7eb321bd/images/82311aecd7bd68cf6cd26204d419c6d85dc9cc905317dadf1bb54a7ec5f4d591.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8444756269454956}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1105535', 'title': 'Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Mar 27, 2012', 'snippet': 'Olaparib as maintenance treatment significantly improved progression-free \nsurvival among patients with platinum-sensitive, relapsed, high-grade \nserous ovarian...', 'thumbnail': 'https://serpapi.com/searches/672218ded771bdbb7eb321bd/images/82311aecd7bd68cf5b1767d4bfcfc3ebc83421e072eb07e80768a4e3586d23cf.png', 'sentiment': 'positive', 'sentiment_prob': 0.5063502192497253}","{'position': 3, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70228-1/abstract', 'title': 'Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial', 'source': 'The Lancet', 'date': 'Mar 29, 2015', 'snippet': 'Maintenance monotherapy with the PARP inhibitor olaparib significantly \nprolonged progression-free survival (PFS) versus placebo in patients with \nplatinum-...', 'thumbnail': 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DNA damage response', 'source': 'Nature', 'date': 'Oct 18, 2021', 'snippet': 'We provide clinical evidence supporting the role of SLFN11 as a DDA therapy \nselection biomarker in SCLC and highlight the need for further clinical...', 'thumbnail': 'https://serpapi.com/searches/672218ded771bdbb7eb321bd/images/82311aecd7bd68cf12f696bafd954eb51d69e3e9dddbf4aace992ab0e5cdb84b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9048330783843994}",,,,,,"['neutral', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03347396,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2027760', 'title': 'Sutimlimab in Cold Agglutinin Disease', 'source': 'The New England Journal of Medicine', 'date': 'Apr 7, 2021', 'snippet': 'We conducted a 26-week multicenter, open-label, single-group study to \nassess the efficacy and safety of intravenous sutimlimab in patients with \ncold agglutinin...', 'thumbnail': 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vaccines', 'source': 'Cold Agglutinin Disease News', 'date': 'Mar 14, 2024', 'snippet': 'People with CAD who were on Enjaymo during clinical trials produced \nprotective antibodies in response to COVID-19 vaccination, a study...', 'thumbnail': 'https://serpapi.com/searches/6722190b7ef9fa1a3166915a/images/f25627a3cb49f3e00c09423c38edba40188ff1b7ff46a5da03d8fd64d0bc4428.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8503730893135071}",,,,,,,,"['neutral', 'negative', 'neutral']",neutral,1 NCT05309200,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20220819005390/en/Ocelot-Bio-Receives-FDA-Orphan-Drug-Designation-for-OCE-205-for-the-Treatment-of-Hepatorenal-Syndrome', 'title': 'Ocelot Bio Receives FDA Orphan Drug Designation for OCE-205 for the Treatment of Hepatorenal Syndrome', 'source': 'Business Wire', 'date': 'Aug 22, 2022', 'snippet': 'Ocelot Bio, Inc., a clinical-stage biopharmaceutical company focused on the \ndevelopment of innovative therapeutics to treat complications of...', 'thumbnail': 'https://serpapi.com/searches/67221b097a12fd124142eed5/images/b3dee6fbed81e9e9231e36943b0615a2ee3fceee5abac50258cc11919c5182c4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8745273351669312}",,,,,,,,,,['neutral'],neutral,1 NCT01218659,"{'position': 1, 'link': 'https://www.nature.com/articles/s41436-019-0451-z', 'title': 'Efficacy of the pharmacologic chaperone migalastat in a subset of male patients with the classic phenotype of Fabry disease and migalastat-amenable variants: data from the phase 3 randomized, multicenter, double-blind clinical trial and extension study | Gen', 'source': 'Nature', 'date': 'Feb 6, 2019', 'snippet': 'Outcomes in patients with Fabry disease receiving migalastat during the \nphase 3 FACETS trial (NCT00925301) were evaluated by phenotype.', 'thumbnail': 'https://serpapi.com/searches/67221b0ccdf15582a043cc3b/images/2cf441f4720aca30f8b55923f8239f27747e549b3f9d8c374f2110175d671215.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9129406213760376}","{'position': 2, 'link': 'https://fabrydiseasenews.com/galafold-migalastat/', 'title': 'Galafold (migalastat) for Fabry disease', 'source': 'Fabry Disease News', 'date': 'Mar 6, 2024', 'snippet': 'Galafold is an approved oral therapy for adults with Fabry disease and \namenable mutations that helps to clear cells of toxic fatty...', 'thumbnail': 'https://serpapi.com/searches/67221b0ccdf15582a043cc3b/images/2cf441f4720aca3013ace41ab8b30a1294592853471a6cc915682f02428cb31d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7855511903762817}","{'position': 3, 'link': 'https://www.nature.com/articles/s41436-020-00968-z', 'title': 'for clinical monitoring of treatment response in migalastat-treated patients with Fabry disease', 'source': 'Nature', 'date': 'Sep 30, 2020', 'snippet': 'To assess the utility of globotriaosylsphingosine (lyso-Gb3) for clinical \nmonitoring of treatment response in patients with Fabry disease...', 'thumbnail': 'https://serpapi.com/searches/67221b0ccdf15582a043cc3b/images/2cf441f4720aca30c24a5ec2369d71414c77f49f8cd7c781d03d0d83707055b7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8680515289306641}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02408913,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-024-00833-z', 'title': 'Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials', 'source': 'Nature', 'date': 'Mar 29, 2024', 'snippet': 'Ebola virus disease (EVD) is a filoviral infection caused by virus species \nof the Ebolavirus genus including Zaire ebolavirus (EBOV) and...', 'thumbnail': 'https://serpapi.com/searches/67221b69460b156b9c59aad2/images/73947c6e57c69d7d02a6e988b6b30685c3ca0bcf78a7912d701c1bfafb087967.png', 'sentiment': 'neutral', 'sentiment_prob': 0.788805365562439}",,,,,,,,,,['neutral'],neutral,1 NCT05104892,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/sanofi-gears-up-for-approval-of-its-btk-inhibitor-meets-phase-iii-endpoint/', 'title': 'Sanofi gears up for approval of its BTK inhibitor, meets Phase III endpoint', 'source': 'Clinical Trials Arena', 'date': 'Apr 23, 2024', 'snippet': ""Sanofi's rilzabrutinib met the primary endpoint in the Phase III persistent \nor chronic immune thrombocytopenia trial."", 'thumbnail': 'https://serpapi.com/searches/67221b737e1d1f5f594b2279/images/ea1d4432ee5cbc297a3510ead19379a515f969695e5822faf02b6ba4fa7c66e7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6001195311546326}",,,,,,,,,,['neutral'],neutral,1 NCT00075049,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-017-0027-3', 'title': 'Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity', 'source': 'Nature', 'date': 'Sep 8, 2017', 'snippet': 'Combining immunostimulants in adjuvants can improve the quality of the \nimmune response to vaccines. Here, we report a unique mechanism of...', 'thumbnail': 'https://serpapi.com/searches/67221932d78a989f7c70e320/images/f6f6df5badf9138b6aef39140e0dcc13f38a44bfabba2628568b12ac882a81b6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.619517982006073}",,,,,,,,,,['positive'],positive,1 NCT01712438,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/octapharma-hemophilia-a-treatment-nuwiq-showing-further-potential-in-phase-3-study/', 'title': 'Hemophilia A Therapy, Nuwiq, Showing Further Potential in Phase 3 Study', 'source': 'Hemophilia News Today', 'date': 'Apr 21, 2017', 'snippet': ""Nuwiq — Octapharma's human cell line recombinant FVIII — is a U.S. Food and \nDrug Administration (FDA)-approved intravenous therapy for patients..."", 'thumbnail': 'https://serpapi.com/searches/672219411397bae53c6c0dab/images/70c09fd7ca7db423e072b71140db2a32f42583e95052fb146e6835e928a1f588.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.511082649230957}",,,,,,,,,,['neutral'],neutral,1 NCT01344993,"{'position': 1, 'link': 'https://www.nature.com/articles/s41536-019-0081-8', 'title': 'Transplantation of human embryonic stem cell-derived retinal pigment epithelial cells (MA09-hRPE) in macular degeneration', 'source': 'Nature', 'date': 'Aug 27, 2019', 'snippet': 'This review focuses on the first generation of hESC-RPE cell line, named as \n“MA09-hRPE” by Astellas Institute of Regenerative Medicine (AIRM), and \nits...', 'thumbnail': 'https://serpapi.com/searches/672219421fc7c5ec485c8c01/images/f4f883df2c2454c38890e3455ec049fc7107f9ff74303efd199daf2cf61ddc94.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9050300717353821}",,,,,,,,,,['neutral'],neutral,1 NCT04200911,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/cns.14463', 'title': ""mTOR signaling and Alzheimer's disease: What we know and where we are?"", 'source': 'Wiley Online Library', 'date': 'Sep 18, 2023', 'snippet': ""Despite the great body of research done on Alzheimer's disease, the \nunderlying mechanisms have not been vividly investigated."", 'thumbnail': 'https://serpapi.com/searches/6722194c6f9f6391e0987f43/images/8acaacbb0403d5d57f9a6cf6527eced775677a1fc78badd8a596312b8f2f5bb3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6370075345039368}",,,,,,,,,,['neutral'],neutral,1 NCT01282268,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/arbaclofen-improved-behavior-half-fragile-x-children-trial/', 'title': 'Arbaclofen Improved Behavior of Almost Half of Children in Phase 3 Trial', 'source': 'Fragile X News Today', 'date': 'Aug 19, 2022', 'snippet': 'The investigational fragile X therapy Arbaclofen improved aspects of \nbehavior in about half of children, ages 5 to 11, in a Phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/672219a3d997ab920de24c2c/images/70a52f6441bf094d322954a899e8d8ea7146c6d43b4d375da30fa577839d1103.png', 'sentiment': 'positive', 'sentiment_prob': 0.5654360055923462}",,,,,,,,,,['positive'],positive,1 NCT01989793,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/agm2.12168', 'title': 'Advances in research on pharmacotherapy of sarcopenia - Feike - 2021 - AGING MEDICINE', 'source': 'Wiley Online Library', 'date': 'Aug 9, 2021', 'snippet': 'Sarcopenia is a comprehensive degenerative disease with the progressive \nloss of skeletal muscle mass with age, accompanied by the loss of...', 'thumbnail': 'https://serpapi.com/searches/67221af22fab6260e6d28f26/images/f16c7724502bb84f02c01d15086a5b534d8834534db55ca903a3be0127fdd540.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8888530731201172}",,,,,,,,,,['neutral'],neutral,1 NCT04283461,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2022483', 'title': 'An mRNA Vaccine against SARS-CoV-2 — Preliminary Report', 'source': 'The New England Journal of Medicine', 'date': 'Jul 14, 2020', 'snippet': 'The mRNA-1273 vaccine induced anti–SARS-CoV-2 immune responses in all \nparticipants, and no trial-limiting safety concerns were identified.', 'thumbnail': 'https://serpapi.com/searches/67221a325c7cb930cf00d3c6/images/8f9d7dbb5c98ee4b9c4305914703b097c8d66f47e1119149584618ec079742ac.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8116927742958069}","{'position': 2, 'link': 'https://www.nih.gov/news-events/news-releases/nih-clinical-trial-evaluating-moderna-covid-19-variant-vaccine-begins', 'title': 'NIH clinical trial evaluating Moderna COVID-19 variant vaccine begins', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Mar 31, 2021', 'snippet': 'This trial is enrolling adult volunteers in the Atlanta, Cincinnati, \nNashville and Seattle areas. At this time, the research sites...', 'thumbnail': 'https://serpapi.com/searches/67221a325c7cb930cf00d3c6/images/8f9d7dbb5c98ee4b27fcf9e02336d8eb3878dae6eb72456179e0311925cf33f7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9455243349075317}","{'position': 3, 'link': 'https://www.nature.com/articles/s41586-020-2798-3', 'title': 'SARS-CoV-2 vaccines in development', 'source': 'Nature', 'date': 'Sep 23, 2020', 'snippet': 'A phase I trial started in March 2020 and there are currently more than 180 \nvaccines at various stages of development.', 'thumbnail': 'https://serpapi.com/searches/67221a325c7cb930cf00d3c6/images/8f9d7dbb5c98ee4be431d29775b2d541d557864f9e1f84373a54200dc4a5d4f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8990486264228821}","{'position': 4, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2028436', 'title': 'Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults', 'source': 'The New England Journal of Medicine', 'date': 'Sep 29, 2020', 'snippet': 'Testing of vaccine candidates to prevent infection with severe acute \nrespiratory syndrome coronavirus 2 (SARS-CoV-2) in an older population...', 'thumbnail': 'https://serpapi.com/searches/67221a325c7cb930cf00d3c6/images/8f9d7dbb5c98ee4bf303370ee29c4fe6319cb12491bc428d3a460d153cad85d5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8452080488204956}","{'position': 5, 'link': 'https://www.nature.com/articles/s41591-021-01527-y', 'title': 'Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis', 'source': 'Nature', 'date': 'Sep 15, 2021', 'snippet': 'The emergence of SARS-CoV-2 variants of concern (VOCs) and variants of \ninterest (VOIs) with decreased susceptibility to neutralization has...', 'thumbnail': 'https://serpapi.com/searches/67221a325c7cb930cf00d3c6/images/8f9d7dbb5c98ee4be77211bb5f8029235e2e48443c3f61fd72e65ef96bb976b5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8676652908325195}",,,,,,"['neutral', 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News Today"", 'date': 'Feb 28, 2023', 'snippet': ""Jotrol, Jupiter Neuroscience's oral formulation of resveratrol, \nsignificantly improved muscle strength, motor coordination, and behavior in \na mouse model of..."", 'thumbnail': 'https://serpapi.com/searches/67221abc8d0417beb1920ea4/images/9fe131ec49d01a9ddc36af0b29dba527cdad19c4a0c17e06028cb3ba1a6110bc.png', 'sentiment': 'positive', 'sentiment_prob': 0.6498141288757324}",,,,,,,,,,['positive'],positive,1 NCT01176669,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-022-00462-6', 'title': 'Apatinib plus vinorelbine versus vinorelbine for metastatic triple-negative breast cancer who failed first/second-line treatment: the NAN trial', 'source': 'Nature', 'date': 'Sep 20, 2022', 'snippet': 'While therapies such as chemotherapy combined with immunotherapy, \nsacituzumab govitecan, and PARP inhibitors are available for metastatic...', 'thumbnail': 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'snippet': 'In this review, we discuss the effects of VPA in the suppression of some \nactivation mechanisms in several immune cells that lead to an \nanti-inflammatory...', 'thumbnail': 'https://serpapi.com/searches/67221b9e3d629b09b8630f85/images/4c46d514a504d56a4294bd2ce3236577d231ac96bc2c76448124fe7a3f33bcbe.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9232328534126282}",,,,,,,,,,['neutral'],neutral,1 NCT03206970,"{'position': 1, 'link': 'https://www.onclive.com/view/indirect-comparison-of-efficacy-of-zanubrutinib-versus-acalabrutinib-in-the-treatment-of-patients-with-relapsed-or-refractory-mantle-cell-lymphoma', 'title': 'Indirect Comparison of Efficacy of Zanubrutinib Versus Acalabrutinib in the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma', 'source': 'OncLive', 'date': 'Jul 5, 2024', 'snippet': 'The study assessed the comparative efficacy of zanubrutinib vs \nacalabrutinib in patients with R/R MCL, in the absence of head-to-head \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/67221bc566d99584933556a5/images/3f5eec8366ed93739a4255dfeae6c32ad922aa6929fcf2701b06b1f42a64a8d7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.884205162525177}",,,,,,,,,,['neutral'],neutral,1 NCT03732807,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/pde.15378', 'title': 'Efficacy and safety of ritlecitinib in adolescents with alopecia areata: Results from the ALLEGRO phase 2b/3 randomized, double-blind, placebo-controlled trial', 'source': 'Wiley Online Library', 'date': 'Jul 17, 2023', 'snippet': 'Background/Objectives This subgroup analysis of the ALLEGRO phase 2b/3 \ntrial (NCT03732807) evaluated the efficacy and safety of ritlecitinib...', 'thumbnail': 'https://serpapi.com/searches/67221bcad364b4c6b6b13245/images/ea3488fa2c2881136324e3021cb4c8ded927ad15b29427f402bafd0ac59d93a3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8307723999023438}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.17442?af=R', 'title': 'Efficacy and safety of ritlecitinib, an oral JAK3/TEC family kinase inhibitor, in adolescent and adult patients with alopecia totalis and alopecia universalis', 'source': 'Wiley Online Library', 'date': '1 month ago', 'snippet': 'This post-hoc analysis of the ALLEGRO phase 2b/3 study (NCT03732807) \nevaluated the efficacy and safety of ritlecitinib, an oral Janus kinase...', 'thumbnail': 'https://serpapi.com/searches/67221bcad364b4c6b6b13245/images/ea3488fa2c288113e7140ecf3bb49a821281749b7d30aff05d9afa20f7fdb438.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8761537671089172}","{'position': 3, 'link': 'https://www.empr.com/home/news/litfulo-approved-for-severe-alopecia-areata-in-adults-adolescents/', 'title': 'Litfulo Approved for Severe Alopecia Areata in Adults, Adolescents', 'source': 'Medical Professionals Reference', 'date': 'Jun 26, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Litfulo™ (ritlecitinib) \nfor the treatment of severe alopecia areata in adults and...', 'thumbnail': 'https://serpapi.com/searches/67221bcad364b4c6b6b13245/images/ea3488fa2c28811301fee5547833f43d7469bedde0bb4d1659893b39fa8c2db3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6619455218315125}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03744026,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45818-7', 'title': 'Repeated blood–brain barrier opening with a nine-emitter implantable ultrasound device in combination with carboplatin in recurrent glioblastoma: a phase I/II clinical trial', 'source': 'Nature', 'date': 'Feb 23, 2024', 'snippet': 'Here, the results of a phase 1/2 single-arm trial (NCT03744026) assessing \nthe safety and efficacy of blood-brain barrier (BBB) disruption...', 'thumbnail': 'https://serpapi.com/searches/67221c0ace1e108230a3a1a8/images/475d8fd85d0d3140d0432d568b56b66d1b1befbd4b0ea1563a15129ba38dfb84.png', 'sentiment': 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Newswire Asia', 'date': 'Feb 21, 2024', 'snippet': 'NANJING, China, Feb. 21, 2024 /PRNewswire/ -- On February 19, 2024, the \nJournal of American Medical Association•Neurology (JAMA NEUROLOGY,...', 'thumbnail': 'https://serpapi.com/searches/67221c1fd364b4c6b6b132a4/images/d2b752b919e956e52bd5d692d1e8f143bc13fe4e2f156131e429e018742404f1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9447066783905029}",,,,,,,,,,['neutral'],neutral,1 NCT00450372,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/abs/pii/S0960852419310193', 'title': 'Multilevel algorithms and evolutionary hybrid tools for enhanced production of arginine deiminase from Pseudomonas furukawaii RS3', 'source': 'ScienceDirect.com', 'date': 'Feb 23, 2020', 'snippet': 'In the present study a high arginine deiminase (ADI) yielding bacterium was \nisolated from soil samples of Haryana, India and identified as \nPseudomonas...', 'thumbnail': 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'https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.121.17073', 'title': 'Effect of KBP-5074 on Blood Pressure in Advanced Chronic Kidney Disease: Results of the BLOCK-CKD Study', 'source': 'American Heart Association Journals', 'date': 'May 10, 2021', 'snippet': 'In patients with resistant or poorly controlled hypertension and advanced \nchronic kidney disease, mineralocorticoid receptor antagonists are...', 'thumbnail': 'https://serpapi.com/searches/67221c3924296a3c4a74debd/images/51a615809cea4e1f9a3e532c85e679e3cafbd6e75ecc8f2dd69b2f93fca83d6a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8651843070983887}",,,,,,,,,,['neutral'],neutral,1 NCT03569631,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/zatolmilast-earns-rare-pediatric-disease-designation-fragile-x/', 'title': 'Zatolmilast earns FDA’s rare pediatric disease designation', 'source': 'Fragile X News Today', 'date': 'Oct 6, 2023', 'snippet': ""The US Food and Drug Administration (FDA) has granted rare pediatric \ndisease (RPD) designation to zatolmilast, Tetra Therapeutics' \ninvestigational oral therapy..."", 'thumbnail': 'https://serpapi.com/searches/67221c4f657c66a83b6685b8/images/29ed462d2c718edee53a6fcd237bb6391e9e4e7890b84c882638079dc63e1bf6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7040296196937561}","{'position': 2, 'link': 'https://fragilexnewstoday.com/news/combination-therapy-gaboxadol-ibudilast-effective-fragile-x-mouse-model/', 'title': 'Combination therapy gaboxadol, ibudilast effective in fragile X mouse model', 'source': 'Fragile X News Today', 'date': 'Mar 1, 2024', 'snippet': 'A combination of ibudilast and gaboxadol was shown to normalize behavior \nand improve memory in a mouse model of fragile X syndrome.', 'thumbnail': 'https://serpapi.com/searches/67221c4f657c66a83b6685b8/images/29ed462d2c718ede44a405cfeb690b6e717e64cd8a4ab116061183a0003582dd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5454389452934265}",,,,,,,,,"['neutral', 'neutral']",neutral,1 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adults with paroxysmal nocturnal...', 'thumbnail': 'https://serpapi.com/searches/67221cea03775620cb8f03fd/images/e83f49a66a20956223e8817c957825a55721d18234f970a2eb3c2f988b4af2a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8320205807685852}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03470805,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-02108-7', 'title': 'INOVATYON/ ENGOT-ov5 study: Randomized phase III international study comparing trabectedin/pegylated liposomal doxorubicin (PLD) followed by platinum at progression vs carboplatin/PLD in patients with recurrent ovarian cancer progressing within 6-12', 'source': 'Nature', 'date': 'Feb 9, 2023', 'snippet': 'Article; Open access; Published: 09 February 2023. 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products: the MDR-105-SAE', 'source': 'BioMed Central', 'date': 'Mar 11, 2023', 'snippet': 'This extension study will be an important step in evaluating safety issues \npertaining to immune tolerance regimens, long-term effects of which are \nlargely...', 'thumbnail': 'https://serpapi.com/searches/67221dd1bbc18bbcc5cb0920/images/2de7ea5a9d45a8bf0fe6240be225d48c127403361c25b5e2ddf1665a8838f891.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.863823413848877}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03884842,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/resp.14197', 'title': 'Respirology | APSR Respiratory Medicine Journal', 'source': 'Wiley Online Library', 'date': 'Jan 10, 2022', 'snippet': 'Pulmonary functional MRI (PfMRI) using inhaled hyperpolarized, \nradiation-free gases (such as 3He and 129Xe) provides a way to directly...', 'thumbnail': 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Antagonists in the Treatment of Plaque Psoriasis', 'source': 'Dermatology Advisor', 'date': 'May 17, 2024', 'snippet': 'Three selective IL-23 inhibitors are currently approved for the treatment \nof plaque psoriasis: guselkumab, risankizumab, and tildrakizumab.', 'thumbnail': 'https://serpapi.com/searches/67221e5a6aa36434b415051a/images/87ebc974208f4acd81a402525f1dfde2419bd6609d09fb710f41b2a63dd95fdd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.890917956829071}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02316457,"{'position': 1, 'link': 'https://www.nature.com/articles/s41586-023-06063-y', 'title': 'Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer', 'source': 'Nature', 'date': 'May 10, 2023', 'snippet': 'Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients1, yet \nharbours mutation-derived T cell neoantigens that are suitable...', 'thumbnail': 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Approves Darzalex Faspro as Injection Therapy for Multiple Myeloma', 'source': 'Myeloma Research News', 'date': 'May 5, 2020', 'snippet': ""The U.S. Food and Drug Administration (FDA) approved Janssen's new \nformulation of daratumumab — a subcutaneous or under-the-skin injection..."", 'thumbnail': 'https://serpapi.com/searches/67221eb10be2f68746bb5490/images/bff53f29f120cdd7b670dedf63243bfd497b70e00aa5b3212f1321f4db60035e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6539252400398254}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/under-the-skin-form-as-effective-as-intravenous-darzalex-myeloma/', 'title': 'Under-the-skin Formulation as Effective as Intravenous Darzalex for Myeloma Patients, Study Says', 'source': 'Myeloma Research News', 'date': 'Mar 11, 2019', 'snippet': 'An under-the-skin injection of daratumumab is as effective as its \nintravenous formulation at reducing tumor burden in multiple myeloma,...', 'thumbnail': 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'https://cervicalcancernews.com/2017/06/09/phase-3-trial-shows-cervical-cancer-responds-to-combination-of-s-1-and-platinol/', 'title': 'Cervical Cancer Responds to Combination of S-1 and Platinol, Phase 3 Trial Shows', 'source': 'Cervical cancer News', 'date': 'Jun 9, 2017', 'snippet': 'Read about a Phase 3 clinical trial showing that cervical cancer responded \nto a combination of S-1 and Platinol chemotherapy.', 'thumbnail': 'https://serpapi.com/searches/67221ef1cf32e0c291d2512d/images/a4caaf846e2f08d351b07423bded3ccde4b50cb9d9c8ec81145c4a9086adb324.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9084898233413696}",,,,,,,,,,['neutral'],neutral,1 NCT05142774,"{'position': 1, 'link': 'https://www.contemporarypediatrics.com/view/dermavant-submits-snda-tapinarof-cream-treat-ad-2-years-and-up', 'title': 'Dermavant submits sNDA for tapinarof cream, 1% to treat AD in patients 2 years and up', 'source': 'Contemporary Pediatrics', 'date': 'Feb 14, 2024', 'snippet': 'Tapinarof cream, 1% (VTAMA; Dermavant Sciences) to treat atopic dermatitis \n(AD) in adult and children 2 years and older has taken another step forward \nin the...', 'thumbnail': 'https://serpapi.com/searches/67221f063b3c320a68572d50/images/e6f726cbbc1bb31c75a3da0675b9d4d50f6aad0476f08415b28b2304fb158d54.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6871433258056641}",,,,,,,,,,['neutral'],neutral,1 NCT04864834,"{'position': 1, 'link': 'https://www.europeanpharmaceuticalreview.com/news/185771/sandoz-to-file-for-approval-of-aflibercept-biosimilar/', 'title': 'Sandoz to file for approval of aflibercept biosimilar', 'source': 'European Pharmaceutical Review', 'date': 'Aug 16, 2023', 'snippet': 'Sandoz intends to seek regulatory approval for its aflibercept biosimilar \nin the US and EU, following positive results for a Phase III...', 'thumbnail': 'https://serpapi.com/searches/67221f7af8b05d603f25a808/images/1aa51cfa061df9816308033fe7cf3f8d8823c545280fe0a05086918b861a4619.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6097245812416077}",,,,,,,,,,['neutral'],neutral,1 NCT02278250,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02436-2', 'title': 'A phase I study of ATR inhibitor gartisertib (M4344) as a single agent and in combination with carboplatin in patients with advanced solid tumours | British Journal of Cancer', 'source': 'Nature', 'date': 'Jan 29, 2024', 'snippet': 'Gartisertib is an oral inhibitor of ataxia telangiectasia and Rad3-related \nprotein (ATR), a key kinase of the DNA damage response.', 'thumbnail': 'https://serpapi.com/searches/67221f7cbb55ff271c7d4d9f/images/3423c7a90b022519173c2afa4723d9295221ddc5a7782d2c7a90371c262c1931.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9014711976051331}","{'position': 2, 'link': 'https://medicalxpress.com/news/2024-01-atr-inhibition-gartisertib-patient-derived.html', 'title': 'ATR inhibition using gartisertib in patient-derived glioblastoma cell lines', 'source': 'Medical Xpress', 'date': 'Jan 17, 2024', 'snippet': 'A new research paper titled ""ATR inhibition using gartisertib enhances cell \ndeath and synergises with temozolomide and radiation in...', 'thumbnail': 'https://serpapi.com/searches/67221f7cbb55ff271c7d4d9f/images/3423c7a90b022519fc8906c939d14d7bb0c37c9c6cd5c779ee14d718fc1d5b3b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9163128733634949}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01741194,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/accera-blames-alzheimers-disease-clinical-trial-failure-on-low-drug-uptake/', 'title': ""Alzheimer's Trial for AC-1204 Fails; Accera Blames Results on Low Uptake"", 'source': ""Alzheimer's News Today"", 'date': 'Mar 3, 2017', 'snippet': ""Yet another Alzheimer's disease clinical trial (NCT01741194) has ended in \ndisappointment. Accera, noting that its Phase 3 trial of AC-1204..."", 'thumbnail': 'https://serpapi.com/searches/67221f7fb5ecbb5708925a2a/images/8b49d27476da5f7a373a388ac26ee03ba6ff892e3b3b16885d110b6af0d1454c.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7464489340782166}",,,,,,,,,,['negative'],negative,0 NCT04901416,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/coeptis-therapeutics-completes-exclusive-license-for-allogeneic-immuno-oncology-platform-and-clinical-stage-assets-from-deverra-therapeutics-301903022.html', 'title': 'Coeptis Therapeutics Completes Exclusive License for Allogeneic Immuno-Oncology Platform and Clinical Stage Assets from Deverra Therapeutics', 'source': 'PR Newswire', 'date': 'Aug 17, 2023', 'snippet': 'Coeptis acquires exclusive rights to two Investigational New Drug (IND) \napplications and two assets in the Phase 1 clinical trial stage.', 'thumbnail': 'https://serpapi.com/searches/67221f857b05caf7f58900d4/images/f9f2d841334fae7e1059429ebf06c728bbfe8435eff920a2e59826f39c16b6de.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8665703535079956}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/coeptis-therapeutics-provides-safety-and-dosing-update-from-phase-1-trials-investigating-dvx201-in-relapsedrefractory-aml-or-high-risk-mds-and-hospitalized-covid-19-infection-301927462.html', 'title': 'Coeptis Therapeutics Provides Safety and Dosing Update from Phase 1 Trials Investigating DVX201 in Relapsed/Refractory AML or High Risk MDS and Hospitalized COVID-19 Infection', 'source': 'PR Newswire', 'date': 'Sep 14, 2023', 'snippet': 'DVX201, a first-ever allogeneic, cord-blood derived, natural killer (NK) \ncell therapy, has been administered to 16 patients with no dose limiting \ntoxicities.', 'thumbnail': 'https://serpapi.com/searches/67221f857b05caf7f58900d4/images/f9f2d841334fae7ec0e85395f09d1dde1f1bc6a80792564e2dfb9a4eb3d52191.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8037376999855042}","{'position': 3, 'link': 'https://www.prnewswire.com/news-releases/coeptis-therapeutics-signs-agreement-to-acquire-allogeneic-immuno-oncology-nk-platform-in-phase-1-clinical-trials-from-deverra-therapeutics-301799765.html', 'title': 'Coeptis Therapeutics Signs Agreement to Acquire Allogeneic Immuno-Oncology NK Platform in Phase 1 Clinical Trials from Deverra Therapeutics', 'source': 'PR Newswire', 'date': 'Apr 18, 2023', 'snippet': 'Proposed transaction would provide Coeptis with two clinical stage assets \nleveraging NK cell therapies in relapsed or refractory acute myeloid \nleukemia (AML)', 'thumbnail': 'https://serpapi.com/searches/67221f857b05caf7f58900d4/images/f9f2d841334fae7ec3a5acf713af2576acdea610b4c8aa24bf1e971c1b0de4b3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8679749965667725}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT05538572,"{'position': 1, 'link': 'https://dailynews.ascopubs.org/do/considering-adjuvant-cdk4-6-inhibitors-monarche-and-natalee-clinical-practice', 'title': 'Considering Adjuvant CDK4/6 Inhibitors?: monarchE and NATALEE in Clinical Practice', 'source': 'ASCO Daily News', 'date': 'Aug 17, 2023', 'snippet': 'Key Points: The NATALEE and monarchE studies looked at adjuvant CDK4/6 \ninhibitors ribociclib and abemaciclib, respectively, as options for...', 'thumbnail': 'https://serpapi.com/searches/6722205b707fd32ced3b4b00/images/bdc113de90469aaafcc5f9b30483a66f39cbc0500381dd2efc48f5849c4f3183.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9415512681007385}",,,,,,,,,,['neutral'],neutral,1 NCT04305470,"{'position': 1, 'link': 'https://www.globenewswire.com/en/news-release/2021/01/12/2157307/0/en/NX-Development-Corp-NXDC-Receives-FDA-Orphan-Drug-Designation-for-Gleolan-aminolevulinic-acid-HCl-in-Meningioma.html', 'title': 'NX Development Corp. (NXDC) Receives FDA Orphan-Drug', 'source': 'GlobeNewswire', 'date': 'Jan 12, 2021', 'snippet': 'Lexington, KY, Jan. 12, 2021 (GLOBE NEWSWIRE) -- NX Development Corp. \n(NXDC), a life sciences company wholly owned by photonamic GmbH & Co.', 'thumbnail': 'https://serpapi.com/searches/67222065fbde0d6899411c25/images/34e68d14d5612ac58a8a30fad048e273ef2bb857d905527e5951ead3f869070a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7542619705200195}",,,,,,,,,,['neutral'],neutral,1 NCT04984993,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-clears-otc-topical-gel-for-treatment-of-erectile-dysfunction/', 'title': 'FDA Clears OTC Topical Gel for Treatment of Erectile Dysfunction', 'source': 'Medical Professionals Reference', 'date': 'Jun 14, 2023', 'snippet': 'The Food and Drug Administration (FDA) has granted marketing authorization \nto Futura Medical for the over-the-counter (OTC) sale of MED3000, a \ntopical...', 'thumbnail': 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Receives $34 Million from BARDA to Continue Advancing Intranasal NDV-based COVID-19 Vaccine into Phase 2b Clinical Efficacy Testing', 'source': 'Business Wire', 'date': 'Jul 30, 2024', 'snippet': 'CastleVax, a clinical stage mucosal vaccine platform company, has received \nan additional Project NextGen award valued at approximately $34...', 'thumbnail': 'https://serpapi.com/searches/6722239793584c1f1a579027/images/54524a8694b22834b9a248d53f187e8f71a1431375da2e30148ed67bb12431bc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6780118346214294}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03875729,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/type-1-diabetes-progression-trials-to-watch-2023/', 'title': 'Delaying type 1 diabetes progression: major trial readouts to watch in 2023', 'source': 'Clinical Trials Arena', 'date': 'Feb 17, 2023', 'snippet': 'Four clinical trials aim to slow or delay type 1 diabetes progression, but \neach targets different patients 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20, 2018', 'snippet': 'This is a pivotal, multicenter, open-label study of moxetumomab pasudotox, \na recombinant CD22-targeting immunotoxin, in hairy cell leukemia...', 'thumbnail': 'https://serpapi.com/searches/67222767fc183d1a7919038a/images/8b53aafc3d80d5ab05f6cc2dc3e840cb0ecbdbdc67aef63a3c207951060a1f9e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7538529634475708}",,,,,,,,,,['neutral'],neutral,1 NCT04975256,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.21.02752', 'title': 'First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRAS', 'source': 'ASCO Publications', 'date': 'Feb 15, 2022', 'snippet': 'Adagrasib 600 mg twice a day was well tolerated and exhibited antitumor \nactivity in patients with advanced solid tumors harboring the KRAS G12C \nmutation.', 'thumbnail': 'https://serpapi.com/searches/6722278272e5c4748b855263/images/a3a7c081cd722bd6f96fe1809085355593293a533b43395ce500190dac49324b.png', 'sentiment': 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2023', 'snippet': 'Chimeric antigen receptor (CAR) T cells provide new perspectives for \ntreatment of hematological malignancies.', 'thumbnail': 'https://serpapi.com/searches/672230932c83d57e0f071805/images/09338af02ed6ea8a9024821d94556e2cfac4a43533c94a334fe3180c58028512.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7708558440208435}",,,,,,,,,,['neutral'],neutral,1 NCT04191577,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/cerevance-adds-47m-funding-will-start-cvn424-phase-3-trial/', 'title': 'Cerevance adds $47M in funding, will start CVN424 Phase 3 trial', 'source': ""Parkinson's News Today"", 'date': 'Apr 30, 2024', 'snippet': ""Cerevance is planning to launch a Phase 3 clinical trial to test its oral \nmolecule CVN424, designed to treat people with early-stage Parkinson's \ndisease."", 'thumbnail': 'https://serpapi.com/searches/672230c3a25104af56cc92ba/images/8c9cd8837a805be65272de7476333c6aa1ec8abba0a8b5a7e3fe36c88b4e7591.png', 'sentiment': 'neutral', 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Inhibiting them \ncan enhance the functions of several types of immune cells,...', 'thumbnail': 'https://serpapi.com/searches/672230d38b84c46fd616808f/images/de1eb75f263b3aaf738befb99fa813c7af25cffc78c58090ca17cef825af8a42.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8865010738372803}",,,,,,,,,,['neutral'],neutral,1 NCT01689207,"{'position': 1, 'link': 'https://www.nature.com/articles/ja201386', 'title': 'Antibiotics in the clinical pipeline in 2013', 'source': 'Nature', 'date': 'Sep 4, 2013', 'snippet': 'The continued emergence of multi-drug-resistant bacteria is a major public \nhealth concern. The identification and development of new...', 'thumbnail': 'https://serpapi.com/searches/67223104f7adbfc5df50721e/images/2ddf1e170fdc9fcba4df7a34d58bcdd940153f55ff86f15b54f3d299cc6e18f7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5702385902404785}",,,,,,,,,,['neutral'],neutral,1 NCT03329690,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-024-02992-x', 'title': 'Trastuzumab deruxtecan in HER2-positive advanced gastric cancer: exploratory biomarker analysis of the randomized, phase 2 DESTINY-Gastric01 trial', 'source': 'Nature', 'date': 'May 14, 2024', 'snippet': 'Trastuzumab deruxtecan (T-DXd) showed statistically significant clinical \nimprovement in patients with human epidermal growth factor receptor \n2-positive (HER2 +...', 'thumbnail': 'https://serpapi.com/searches/67223150a775f24217d49cb3/images/94d46d9002e805fd82d29ad1349692cd7fe4dbdff20aa000d1cf83abd1c3e838.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7972193956375122}","{'position': 2, 'link': 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NOV03 for the Treatment of Patients with Dry Eye Disease', 'source': 'Business Wire', 'date': 'Oct 24, 2018', 'snippet': 'NOV03 (100% perfluorohexyloctane) is a preservative-free ophthalmic \nsolution and the first drug developed to treat evaporative DED associated \nwith meibomian...', 'thumbnail': 'https://serpapi.com/searches/672231b5b7d31daeb5020928/images/bfd41d19bf61d457e41500031a75e06c4185e650ccc6e622f6a1bfc4bb6fea23.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5880693793296814}",,,,,,,,,,['positive'],positive,1 NCT00882102,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.25854', 'title': 'American Journal of Hematology | Blood Research Journal', 'source': 'Wiley Online Library', 'date': 'Apr 30, 2020', 'snippet': 'A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed \nand relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome.', 'thumbnail': 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'title': 'Effectiveness of Fluticasone Furoate–Vilanterol for COPD in Clinical Practice', 'source': 'The New England Journal of Medicine', 'date': 'Sep 4, 2016', 'snippet': 'Evidence for the management of chronic obstructive pulmonary disease (COPD) \ncomes from closely monitored efficacy trials involving groups of...', 'thumbnail': 'https://serpapi.com/searches/672232d88b7ba7a724a7f131/images/fd9e76ddbc7e2a1eed5323fbb8183694ccc50ef76d53b5fe79281e7eaac8b5e7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8639252781867981}",,,,,,,,,,['neutral'],neutral,1 NCT03790839,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-36946-7', 'title': 'A phase I open-label clinical trial to study drug-drug interactions of Dorzagliatin and Sitagliptin in patients with type 2 diabetes and obesity', 'source': 'Nature', 'date': 'Mar 14, 2023', 'snippet': 'This is a phase 1, open-label, single-sequence, multiple-dose, \nsingle-center trial conducted in the US (NCT03790839), to evaluate 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(NASDAQ: BCLI), a leading \ndeveloper of adult stem cell therapeutics for neurodegenerative...', 'thumbnail': 'https://serpapi.com/searches/672233f8b57db8b81dcfe21f/images/3482470dbcaf50a94d3cb67a6fa49ee3fcaf651a322cce3f036be1e47cac6ae1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9033440947532654}","{'position': 2, 'link': 'https://www.streetinsider.com/Basic+Content/BrainStorm+to+Announce+Third+Quarter+2023+Financial+Results+and+Provide+a+Corporate+Update/22369647.html', 'title': 'BrainStorm to Announce Third Quarter 2023 Financial Results and Provide a Corporate Update', 'source': 'StreetInsider', 'date': 'Nov 7, 2023', 'snippet': '7, 2023 /PRNewswire/ -- BrainStorm Cell Therapeutics Inc. 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effective with dementia"", 'source': ""Parkinson's News Today"", 'date': 'Dec 19, 2023', 'snippet': ""The Phase 3 HARMONY trial found Nuplazidoutperformed a placebo at managing \npsychosis in Parkinson's disease dementia patients."", 'thumbnail': 'https://serpapi.com/searches/672236ed8d1473e38aba931c/images/4f10701a6aa958ddb25a878ff62d267d0a7e35519e6fa27ebeb26d6b5dbe606e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5408130288124084}","{'position': 4, 'link': 'https://alzheimersnewstoday.com/news/nuplazid-significantly-delays-relapses-dementia-related-psychosis-alzheimers-harmony-trial/', 'title': 'Nuplazid Significantly Delays Relapses in Dementia-related Psychosis, Phase 3 Study Shows', 'source': ""Alzheimer's News Today"", 'date': 'Oct 11, 2019', 'snippet': ""Treatment with Nuplazid significantly delays time to a psychosis relapse in \ndementia-related disorders such as Alzheimer's, a Phase 3 trial..."", 'thumbnail': 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The Janus kinase/signal transduction and..."", 'thumbnail': 'https://serpapi.com/searches/67223883d11a89f6ae7eca2b/images/11c106513d52223cbaa0fe828280a980f213684fa897d1ba070476d16a2e8fa7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8893328309059143}",,,,,,,,,,['neutral'],neutral,1 NCT01102426,"{'position': 1, 'link': 'https://www.researchgate.net/figure/The-marine-organism-Aplidium-albicans-reused-with-permission-from-PharmaMar-R-Spain_fig4_329338056', 'title': 'Fig. 4. The marine organism Aplidium albicans (reused with permission...', 'source': 'ResearchGate', 'date': 'Dec 2, 2018', 'snippet': 'Intrinsic or acquired drug resistance, adverse drug reactions and tumor \nheterogeneity between and within cancer patients limit the efficacy of \nclinical...', 'thumbnail': 'https://serpapi.com/searches/67223a9854605cf4e9888ab5/images/6ee1d3dccd9a8182dd2dd11bc08cffe052da8b907ed0a6ddcc65da4c2b4b7287.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6151346564292908}",,,,,,,,,,['negative'],negative,0 NCT00575055,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1304839', 'title': ""Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease"", 'source': 'The New England Journal of Medicine', 'date': 'Jan 23, 2014', 'snippet': ""Bapineuzumab, a humanized anti–amyloid-beta monoclonal antibody, is in \nclinical development for the treatment of Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/67223b1c7d533ebcf913a8d6/images/ed02d71d2bd11e5c4b156f80360a6df78922332668a486a7db504cc31eae6803.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8981547355651855}",,,,,,,,,,['neutral'],neutral,1 NCT03136185,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20201119005341/en/Imago-BioSciences-Raises-80-Million-in-Series-C-Financing', 'title': 'Imago BioSciences Raises $80 Million in Series C Financing', 'source': 'Business Wire', 'date': 'Nov 19, 2020', 'snippet': 'Imago BioSciences, Inc. (Imago), a clinical-stage biopharmaceutical company \ndeveloping innovative treatments for myeloproliferative neoplasms, today \nannounced...', 'thumbnail': 'https://serpapi.com/searches/6722388af59d0018ddb8c975/images/d2b027c81b2e5fa3892f0772a7c7f3a0e01f7e9a878a33bbe50c1cac8c3bbe6d.png', 'sentiment': 'positive', 'sentiment_prob': 0.6281275153160095}",,,,,,,,,,['positive'],positive,1 NCT02459886,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/biogen-announcement-discontinue-cinpanemab-parkinsons/', 'title': ""Biogen Discontinues Development of Cinpanemab for Parkinson's"", 'source': ""Parkinson's News Today"", 'date': 'Feb 4, 2021', 'snippet': 'Due to negative clinical trial findings, Biogen has discontinued the \ndevelopment of cinpanemab (BIIB054), an investigational medication...', 'thumbnail': 'https://serpapi.com/searches/6722388ca775f24217d4a1cd/images/d0a35cab265426cb4a97a3bec742cf19129cefae134896dd688c1120b59ae56a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 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Clinical Trial', 'source': 'Cervical cancer News', 'date': 'Nov 23, 2016', 'snippet': ""CEL-SCI's Phase 3 clinical trial assessing its investigational drug \nMultikine in patients with squamous cell carcinoma of the head and neck \n(SCCHN) recently..."", 'thumbnail': 'https://serpapi.com/searches/6722399d8e13c9f8fd73c88f/images/7b449671712395344b2b629575ee8174c68b4f77af86a3055199ceaa4f4e6306.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8735347390174866}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02912104,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S2589537024003237', 'title': 'Safety and efficacy of allogenic human amniotic epithelial cells transplantation via ovarian artery in patients with premature ovarian failure: a single-arm, phase 1 clinical trial', 'source': 'ScienceDirect.com', 'date': 'Jul 31, 2024', 'snippet': 'Premature ovarian failure (POF) is a prevalent and severe condition that \nimpairs female health but there is currently no effective treatment \navailable to...', 'thumbnail': 'https://serpapi.com/searches/672239e2a9210b1b7b08908c/images/1a95536cae4e459586c0aa4c912578f63699c266d6cb09f50a62ccd1f7fdc41c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5064108371734619}",,,,,,,,,,['neutral'],neutral,1 NCT00650091,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1113354', 'title': 'Prednisone, Azathioprine, and N -Acetylcysteine for Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'May 20, 2012', 'snippet': 'A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has \nbeen widely used as a treatment for idiopathic pulmonary fibrosis.', 'thumbnail': 'https://serpapi.com/searches/67223b4efc40bf18bd76cce2/images/5b07fc0bc9691a2625d0dfdb8ad215ba01473cce26a6422705742bfcf977a959.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8677869439125061}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.794997/full', 'title': 'Targeting Oxidative Stress as a Therapeutic Approach for Idiopathic Pulmonary Fibrosis', 'source': 'Frontiers', 'date': 'Feb 6, 2024', 'snippet': 'Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease \ncharacterized by an abnormal reepithelialisation, an excessive tissue \nremodelling...', 'thumbnail': 'https://serpapi.com/searches/67223b4efc40bf18bd76cce2/images/5b07fc0bc9691a260da91b865bf58fed127551dddfb4e4127f8ef51ce98e3d86.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6219959855079651}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT02370498,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/gastric-cancer-data-suggest-clinical-efficacy-molecular-determinant-risk/', 'title': 'Study Identifies Molecular Determinants of Gastric/Gastroesophageal Junction Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Aug 10, 2021', 'snippet': 'Data suggest that tissue tumor mutational burden is a significant and \nindependent predictor of clinical efficacy.', 'thumbnail': 'https://serpapi.com/searches/67223b6cb2ebaeb57e2b385e/images/596ff65385086511cfbf9812f5aa065ad050ea11f66e8487b82d6e3a51ee35c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7947157025337219}",,,,,,,,,,['neutral'],neutral,1 NCT04184622,"{'position': 1, 'link': 'https://investor.lilly.com/news-releases/news-release-details/tirzepatide-reduced-risk-developing-type-2-diabetes-94-adults', 'title': 'Tirzepatide reduced the risk of developing type 2 diabetes by 94% in adults with pre-diabetes and obesity or overweight', 'source': 'Eli Lilly and Company', 'date': 'Aug 20, 2024', 'snippet': '176-week SURMOUNT-1 Phase 3 study in adults with pre-diabetes is the \nlongest completed trial of tirzepatide to date.', 'thumbnail': 'https://serpapi.com/searches/67223b83e30abcd3862667f0/images/d33a14507c1ac8bb7acba22ccab5f8a84ba69d88bd98029e8f88f79d25b41161.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5982460975646973}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/news/zepbound-eli-lilly-diabetes-prevention/', 'title': 'Lilly’s blockbuster Zepbound prevents type 2 diabetes in obese patients', 'source': 'Clinical Trials Arena', 'date': 'Aug 20, 2024', 'snippet': ""Eli Lilly's blockbuster drug Zepbound (tirzepatide) has been effective in \npreventing the development of type 2 diabetes (T2D) in patients who are \noverweight or..."", 'thumbnail': 'https://serpapi.com/searches/67223b83e30abcd3862667f0/images/d33a14507c1ac8bba410bab5509bd2279b7b771724cdea28833566a70c2a4432.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5146840214729309}","{'position': 3, 'link': 'https://investor.lilly.com/news-releases/news-release-details/lillys-surmount-1-results-published-new-england-journal-medicine', 'title': ""Lilly's SURMOUNT-1 results published in The New England Journal of Medicine show tirzepatide achieved between 16.0% and 22.5% weight loss in adults with obesity or overweight"", 'source': 'Eli Lilly and Company', 'date': 'May 13, 2022', 'snippet': ""Detailed results from Lilly 's first phase 3 trial in obesity or overweight \npresented at the American Diabetes Association's ® 82nd..."", 'thumbnail': 'https://serpapi.com/searches/67223b83e30abcd3862667f0/images/d33a14507c1ac8bb9cdbdc65ba2eec8c3e4f4a06b4f9208407beb2a05e38145d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7818043828010559}","{'position': 4, 'link': 'https://www.endocrinologyadvisor.com/news/tirzepatide-reduces-10-year-atherosclerosis-risk-among-patients-with-obesity/', 'title': 'Tirzepatide Reduces 10-Year Atherosclerosis Risk Among Patients With Obesity', 'source': 'Endocrinology Advisor', 'date': 'Nov 30, 2023', 'snippet': 'Tirzepatide treatment is associated with a significant reduction in 10-year \nrisk for atherosclerosis among individuals with obesity or overweight and \nwithout...', 'thumbnail': 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22.5% weight loss in adults with obesity or overweight in SURMOUNT-1"", 'source': 'Eli Lilly and Company', 'date': 'Apr 28, 2022', 'snippet': 'Participants taking tirzepatide lost up to 52 lb. (24 kg) in this 72-week \nphase 3 study. 63% of participants taking tirzepatide 15 mg...', 'thumbnail': 'https://serpapi.com/searches/67223b83e30abcd3862667f0/images/d33a14507c1ac8bb34a25447add72a600ff5d5c5b7fd42c723dbffc266c41d27.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7193176746368408}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03761056,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01731-4', 'title': 'Axicabtagene ciloleucel as first-line therapy in high-risk large B-cell lymphoma: the phase 2 ZUMA-12 trial', 'source': 'Nature', 'date': 'Mar 21, 2022', 'snippet': 'We conclude that axi-cel is highly effective as part of first-line therapy \nfor high-risk LBCL, with a manageable safety profile.', 'thumbnail': 'https://serpapi.com/searches/67223b8d7ca6b36e4282f45b/images/72ece01b16a1182203240861ae35c567024e15c4aaa614902e774dadf3213989.png', 'sentiment': 'positive', 'sentiment_prob': 0.62087082862854}",,,,,,,,,,['positive'],positive,1 NCT03467113,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Fenfluramine%20%20%28Fintepla%29', 'title': 'Fenfluramine (Fintepla)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Dravet Syndrome, A Study to Evaluate Safety, Tolerability, and \nPharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to \nLess...', 'thumbnail': 'https://serpapi.com/searches/67223bd048c429afb956e2e9/images/598efd6ca4e31c9e47e52e07db5064ee5d8d5f82f8f4064179a9d63e6180619b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8484590649604797}",,,,,,,,,,['neutral'],neutral,1 NCT00423410,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-020-71246-w', 'title': 'Dose–response assessment by quantitative MRI in a phase 1 clinical study of the anti-cancer vascular disrupting agent crolibulin', 'source': 'Nature', 'date': 'Sep 2, 2020', 'snippet': 'In a multisite phase 1 clinical study of crolibulin (NCT00423410), we \nmeasured treatment-induced changes in tumor perfusion and water diffusivity \n(ADC)', 'thumbnail': 'https://serpapi.com/searches/67223c0f6de1e4461d91474c/images/3ac37f60ab47498c8f6db1ac8b88787121846c941ee9ce859ee3337f582dcc8d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9077230095863342}",,,,,,,,,,['neutral'],neutral,1 NCT04712500,"{'position': 1, 'link': 'https://www.manilatimes.net/2024/10/29/tmt-newswire/pr-newswire/kind-presents-positive-results-of-and017-to-treat-anemia-associated-with-chronic-kidney-disease-in-two-phase-ii-and-two-phase-i/1992905', 'title': 'KIND Presents Positive Results of AND017 to Treat Anemia Associated with Chronic Kidney Disease in Two Phase II and Two Phase I', 'source': 'The Manila Times', 'date': '1 day ago', 'snippet': 'Clinical Trials at American Society of Nephrology (ASN) - Kidney Week 2024. \nSAN FRANCISCO, Oct. 29, 2024 /PRNewswire/ -- Kind Pharmaceutical...', 'thumbnail': 'https://serpapi.com/searches/67223c221f3d4b4c18f5c08a/images/74514df067118fe582e2ae4c4ab890b236231156948057be6c4f47602c1c46ba.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6056104302406311}",,,,,,,,,,['neutral'],neutral,1 NCT00234832,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1003114', 'title': 'Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects', 'source': 'The New England Journal of Medicine', 'date': 'Sep 2, 2010', 'snippet': 'The Sibutramine Cardiovascular Outcomes (SCOUT) trial evaluated the \nlong-term effects of sibutramine treatment combined with diet and exercise \non the rates of...', 'thumbnail': 'https://serpapi.com/searches/67223d9ed0253ebcf855dc61/images/a7bfdd1f9067afdb144d2bbbbc320dfe26845c0611049e2904cc86a97ea54740.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9058936834335327}",,,,,,,,,,['neutral'],neutral,1 NCT01430416,"{'position': 1, 'link': 'https://www.nature.com/articles/s41417-022-00457-2', 'title': 'Protein kinase inhibitor responses in uveal melanoma reflects a diminished dependency on PKC-MAPK signaling', 'source': 'Nature', 'date': 'Mar 29, 2022', 'snippet': 'In this study, we examined the signaling and functional effects of two PKC \ninhibitors (AEB071 and IDE196) in a panel of UM cell models.', 'thumbnail': 'https://serpapi.com/searches/67223e36e45f339e0173778c/images/af28dee7fff0a8c499331eef60405c2a570100fb8950352e447d4030d1109991.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8511186838150024}",,,,,,,,,,['neutral'],neutral,1 NCT03823287,"{'position': 1, 'link': 'https://www.globenewswire.com/de/news-release/2023/04/25/2654401/0/en/New-Vabysmo-data-suggest-greater-retinal-drying-versus-aflibercept-in-nAMD-and-DME.html', 'title': 'New Vabysmo data suggest greater retinal drying versus aflibercept in nAMD and DME', 'source': 'GlobeNewswire', 'date': 'Apr 25, 2023', 'snippet': ""Post-hoc analyses from four phase III studies indicate Vabysmo dried \nretinal fluid faster with fewer injections in neovascular or 'wet'..."", 'thumbnail': 'https://serpapi.com/searches/67223e49d78a989f43d44cd7/images/e85ccf5749f39218d7a93e3a857e0c64175c6b94a605e5ffc7ae7e78af1b6881.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8941206932067871}",,,,,,,,,,['neutral'],neutral,1 NCT02885610,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.539797/full', 'title': 'A Comprehensive Review of Biological Agents for Lupus: Beyond Single Target', 'source': 'Frontiers', 'date': 'Feb 6, 2024', 'snippet': 'This review summarizes the biological agents that are in the preclinical \nand clinical trial study of SLE.', 'thumbnail': 'https://serpapi.com/searches/67223e5bcf32e0c291d26c05/images/c8785598eb81e4d3175d91b4184877c28596d5027139e8287c59c1d9a81abd8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9278648495674133}",,,,,,,,,,['neutral'],neutral,1 NCT03571620,"{'position': 1, 'link': 'http://www.biospectator.com/view/news_print.php?varAtcId=7298', 'title': ""Qurient, presented the P2a results for atopic dermatitis candidate 'Q301' at the AAD 2019"", 'source': '바이오스펙테이터', 'date': 'Mar 15, 2019', 'snippet': '바이오스펙테이터 Sungmin Kim 기자. At the largest dermatology conference in the \nUnited States, Qurient delivered oral and poster...', 'thumbnail': 'https://serpapi.com/searches/67223caaecf150161f81e2a9/images/e85dc127d07af42893f87d368aae4f19b5c9de7f39561b65ac11c9487e86c656.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8518079519271851}",,,,,,,,,,['neutral'],neutral,1 NCT01825785,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1155/2016/6217286', 'title': 'Sclerostin Antibody Therapy for the Treatment of Osteoporosis: Clinical Prospects and Challenges', 'source': 'Wiley Online Library', 'date': 'May 26, 2016', 'snippet': 'Sclerostin antibody treatment has demonstrated efficacy and superiority \ncompared to other anabolic treatments for increasing bone formation in both \npreclinical...', 'thumbnail': 'https://serpapi.com/searches/67223cc03c944b51303a302e/images/a17730b98943fcb7c753167619c210049d36c616590941c65774ce9d08f2e940.png', 'sentiment': 'neutral', 'sentiment_prob': 0.635117769241333}",,,,,,,,,,['neutral'],neutral,1 NCT01737398,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1716793', 'title': 'Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 4, 2018', 'snippet': 'Hereditary transthyretin amyloidosis is caused by pathogenic \nsingle-nucleotide variants in the gene encoding transthyretin (TTR) that \ninduce...', 'thumbnail': 'https://serpapi.com/searches/67223cc8c5d7695ce97d135a/images/dd801045b8c73fa042b084b46cf2367cafc81d21410bf78eabe4cb431540ab4a.png', 'sentiment': 'negative', 'sentiment_prob': 0.6270034313201904}","{'position': 2, 'link': 'https://fapnewstoday.com/news/real-world-study-shows-long-term-benefits-fap-with-tegsedi-treatment/', 'title': 'Long-term benefits of Tegsedi for FAP seen in real-world study', 'source': 'FAP News Today', 'date': 'May 13, 2024', 'snippet': 'Tegsedi (inotersen) safely and effectively slowed the progression of \npolyneuropathy, or damage to multiple nerves, when taken for up to about \nsix years for 10...', 'thumbnail': 'https://serpapi.com/searches/67223cc8c5d7695ce97d135a/images/dd801045b8c73fa0e540e41054a36087bc12befcc35a92382e1dbd25a60649bb.png', 'sentiment': 'positive', 'sentiment_prob': 0.5440833568572998}","{'position': 3, 'link': 'https://fapnewstoday.com/news/results-fully-enrolled-fap-neuro-ttransform-trial-eplontersen-expected-mid-2022/', 'title': 'Results From Fully Enrolled NEURO-TTRansform Trial Due Mid-2022', 'source': 'FAP News Today', 'date': 'Aug 2, 2021', 'snippet': ""Patient enrollment is complete for the NEURO-TTRansform trial testing \nIonis' eplontersen in adults with FAP, with results due in mid-2022."", 'thumbnail': 'https://serpapi.com/searches/67223cc8c5d7695ce97d135a/images/dd801045b8c73fa0e933ef19809cec947be0187ccc8823172a88e35ea1749fa2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8340455889701843}",,,,,,,,"['negative', 'positive', 'neutral']",negative,0 NCT04097314,"{'position': 1, 'link': 'https://www.researchgate.net/publication/376715534_Precision_Pharmacotherapy_With_Zibotentan_in_Microvascular_Angina_a_randomized_placebo-controlled_cross-over_trial', 'title': '(PDF) Precision Pharmacotherapy With Zibotentan in Microvascular Angina: a randomized, placebo-controlled, cross-over trial.', 'source': 'ResearchGate', 'date': 'Dec 21, 2023', 'snippet': 'The trial compared zibotentan, an oral endothelin A receptor selective \nantagonist, with placebo in 118 patients with microvascular angina.', 'thumbnail': 'https://serpapi.com/searches/67223d18a775f2424b78397a/images/2aed15c2b2a5e9220db98279c4caa930290584f5ac1caee64a67963177cea959.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8792782425880432}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1156456/full', 'title': 'Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)', 'source': 'Frontiers', 'date': 'Jun 16, 2023', 'snippet': ""In today's era of individualized precision medicine drug repurposing \nrepresents a promising approach to offer patients fast access to novel \ntreatments."", 'thumbnail': 'https://serpapi.com/searches/67223d18a775f2424b78397a/images/2aed15c2b2a5e9227bf3e5163852dc239e1edaf24d7d871e4618d72f48ec397b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5737496614456177}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT03560531,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-023-00523-4', 'title': 'An emerging generation of endocrine therapies in breast cancer: a clinical perspective | npj Breast Cancer', 'source': 'Nature', 'date': 'Apr 5, 2023', 'snippet': 'Anti-estrogen therapy is a key component of the treatment of both early and \nadvanced-stage hormone receptor (HR)-positive breast cancer.', 'thumbnail': 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'https://www.nejm.org/doi/full/10.1056/NEJMoa1611299', 'title': 'Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy', 'source': 'The New England Journal of Medicine', 'date': 'Oct 8, 2016', 'snippet': 'On the basis of data from a phase 2 trial that compared the checkpoint \ninhibitor ipilimumab at doses of 0.3 mg, 3 mg, and 10 mg per kilogram...', 'thumbnail': 'https://serpapi.com/searches/67223f21d9c3e646d94ae442/images/dace67e9ace08bab8166c7beb720e031d4d541f36f8f4de2ae67cc4f18cd5f8f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8651557564735413}",,,,,,,,,,['neutral'],neutral,1 NCT03639194,"{'position': 1, 'link': 'https://dailynews.ascopubs.org/do/adc-novel-sez6-target-well-tolerated-preliminary-efficacy-small-cell-lung-cancer-phase', 'title': 'ADC With Novel SEZ6 Target Well-Tolerated With Preliminary Efficacy in Small Cell Lung Cancer Phase 1 Trial', 'source': 'ASCO Daily News', 'date': 'Jun 5, 2023', 'snippet': 'ABBV-011, an antibody-drug conjugate (ADC) targeting seizure-related \nhomolog protein (SEZ6), was well-tolerated and demonstrated antitumor \nactivity.', 'thumbnail': 'https://serpapi.com/searches/67223f29d11a89f6ae7ecfad/images/36a7e94f3f7ff20f8fcdf9e56acf1aeebfb5f4526c6582c5bde86f1e92a07e6a.png', 'sentiment': 'positive', 'sentiment_prob': 0.521563708782196}",,,,,,,,,,['positive'],positive,1 NCT00123916,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1507574', 'title': 'Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy', 'source': 'The New England Journal of Medicine', 'date': 'Sep 1, 2015', 'snippet': ""The role of trypanocidal therapy in patients with established Chagas' \ncardiomyopathy is unproven.We conducted a prospective, multicenter,..."", 'thumbnail': 'https://serpapi.com/searches/6722408b7ebde5d9be3a9049/images/ab289c72c63151320bb0b8bdbc00c13476e5618b35543194cccb5eaef300fb3a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6657135486602783}",,,,,,,,,,['neutral'],neutral,1 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Administration (FDA) has approved Jatenzo (testosterone \nundecanoate; Clarus Therapeutics) capsules for testosterone...', 'thumbnail': 'https://serpapi.com/searches/672240a6069e57ccad4130cc/images/2e078a5469dcd790186da2ca352d443f173e140d6a3b17792ca7416d1778db5b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8623235821723938}",,,,,,,,,,['neutral'],neutral,1 NCT02683213,"{'position': 1, 'link': 'https://www.researchgate.net/publication/339582818_Update_on_the_EFFECTS_study_of_fluoxetine_for_stroke_recovery_A_randomised_controlled_trial_in_Sweden', 'title': '(PDF) Update on the EFFECTS study of fluoxetine for stroke recovery: A randomised controlled trial in Sweden', 'source': 'ResearchGate', 'date': 'Aug 12, 2020', 'snippet': 'PDF | Studies have suggested that fluoxetine might improve neurological \nrecovery after stroke, but the results remain inconclusive. The EFFECTS.', 'thumbnail': 'https://serpapi.com/searches/6722410edb3ac9d20ba6dbcf/images/0329f6333540fe5acf06a31ab4aef53ad062661074eb18d79a449bc28e328a2d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9180974960327148}",,,,,,,,,,['neutral'],neutral,1 NCT02410772,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2033400', 'title': 'Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis', 'source': 'The New England Journal of Medicine', 'date': 'May 5, 2021', 'snippet': 'In an open-label, phase 3, randomized, controlled trial involving persons \nwith newly diagnosed pulmonary tuberculosis from 13 countries,...', 'thumbnail': 'https://serpapi.com/searches/67224139efad21cb4a6af16c/images/c98bb78fe7b788a28d0e93839c06d5ed456c1b15fac19d67f5e6d6e7dc0c9ba3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9226011633872986}",,,,,,,,,,['neutral'],neutral,1 NCT03819647,"{'position': 1, 'link': 'https://www.nature.com/articles/s41581-022-00661-1', 'title': 'Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope', 'source': 'Nature', 'date': 'Jan 5, 2023', 'snippet': 'Primary hyperoxaluria (PH) is an inherited disorder that results from the \noverproduction of endogenous oxalate, leading to recurrent kidney...', 'thumbnail': 'https://serpapi.com/searches/672241a149ea55cdb86953f6/images/1b9f62983ac2c19511cb59aea0c1968003b4cb1dcfa88f5e366f751c3814cf4c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8578411340713501}",,,,,,,,,,['neutral'],neutral,1 NCT03717272,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02381-w', 'title': 'receptor for cannabis use disorder: phase 1 and phase 2a randomized trials', 'source': 'Nature', 'date': 'Jun 8, 2023', 'snippet': 'AEF0117, the first of a new pharmacological class, is a signaling-specific \ninhibitor of the cannabinoid receptor 1 (CB 1 -SSi).', 'thumbnail': 'https://serpapi.com/searches/672241d55ddfba5b347bae83/images/9f55e64768606847dd159f98334eb531b0d6b74f5a854ac2e6f22805b69608e6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9198508858680725}",,,,,,,,,,['neutral'],neutral,1 NCT02297945,"{'position': 1, 'link': 'https://cushingsdiseasenews.com/news/metopirone-safely-normalized-significantly-lowered-urine-cortisol-levels-cushings-patients-clinical-trial/', 'title': ""Metopirone Fares Well in Phase 3/4 Clinical Trial of Cushing's Patients"", 'source': ""Cushing's Disease News"", 'date': 'Sep 18, 2020', 'snippet': ""Metopirone (metyrapone) safely normalized, or at least lowered by half, the \nlevels of cortisol found in the urine of patients with endogenous \nCushing's..."", 'thumbnail': 'https://serpapi.com/searches/67224200fc183d1a4363f5f0/images/d73293d9a098525da8da72db9eade73fa90c400e9dde743935ff7184fe12217b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5527316331863403}",,,,,,,,,,['neutral'],neutral,1 NCT00526149,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-94259-5', 'title': 'High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma', 'source': 'Nature', 'date': 'Jul 20, 2021', 'snippet': 'We demonstrated that combining navitoclax with irradiation resulted in \nsynergistic in vitro antitumor effects in HNSCC cell lines.', 'thumbnail': 'https://serpapi.com/searches/6722420acc48791e952690ea/images/1e52debcbcdcbfc027a6bc2e9bb43e3e9148fa8e67aaf4720127434f9e4754ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8691082000732422}",,,,,,,,,,['neutral'],neutral,1 NCT02151526,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/first-sickle-cell-disease-patient-successfully-treated-with-gene-therapy/', 'title': ""Sickle Cell Patient Becomes World's First to be Successfully Treated WIth Gene Therapy"", 'source': 'Sickle Cell Disease News', 'date': 'Mar 7, 2017', 'snippet': ""A 13-year-old boy with sickle cell disease has become the world's first \npatient to be successfully treated with gene therapy."", 'thumbnail': 'https://serpapi.com/searches/672242a11b4e34fdab3d7d56/images/dcf14c07bf6715869f8e95c98aad0725ca388fd9bc28216177c3326fe297b791.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6654171347618103}",,,,,,,,,,['neutral'],neutral,1 NCT02326194,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60553-0/abstract', 'title': 'Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trial', 'source': 'The Lancet', 'date': 'Mar 24, 2015', 'snippet': 'Up to now, all tested Ebola virus vaccines have been based on the virus \nstrain from the Zaire outbreak in 1976. We aimed to assess the...', 'thumbnail': 'https://serpapi.com/searches/6722436fee468296d35793ad/images/66a7029f973c49861c343a4fea44c4b617a42debb36e596538efa21e0fe3bf8f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8658244609832764}",,,,,,,,,,['neutral'],neutral,1 NCT01485926,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-023-00572-9', 'title': 'Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer | npj Breast Cancer', 'source': 'Nature', 'date': 'Sep 27, 2023', 'snippet': 'HER2-positive (HER2+) breast cancer accounts for 20–25% of all breast \ncancers. Predictive biomarkers of neoadjuvant therapy response are...', 'thumbnail': 'https://serpapi.com/searches/6722438cbd7cf0d69d204616/images/193f84881eaeb7084264c025658faaf42845f28ea6bc85b40c6e1813c6259510.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7186137437820435}","{'position': 2, 'link': 'https://www.nature.com/articles/s41416-023-02375-y', 'title': 'Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy | British Journal of Cancer', 'source': 'Nature', 'date': 'Jul 28, 2023', 'snippet': 'The phase II neo-adjuvant clinical trial ICORG10-05 (NCT01485926) compared \nchemotherapy in combination with trastuzumab, lapatinib or both...', 'thumbnail': 'https://serpapi.com/searches/6722438cbd7cf0d69d204616/images/193f84881eaeb70838fe09f65c255872371394fec6e6670b980551983bdad9fa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8899237513542175}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01358175,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1505066', 'title': 'Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 24, 2015', 'snippet': 'In two double-blind trials, we randomly assigned patients to receive \nsecukinumab or placebo. In MEASURE 1, a total of 371 patients received...', 'thumbnail': 'https://serpapi.com/searches/672245d4e92456707116f58a/images/02cee8506acfe07639cac40dbeb7c82dd332a79d33329c56e6c4e8096a80134f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8936644792556763}","{'position': 2, 'link': 'https://ankylosingspondylitisnews.com/2022/10/06/real-world-database-study-cosentyx-side-effects/', 'title': 'Real-world Database Study Used to Identify Cosentyx Side Effects |...', 'source': 'Ankylosing Spondylitis News', 'date': 'Oct 6, 2022', 'snippet': 'Diarrhea, cold-like symptoms, itchy skin, and rash are the most common \nreal-world side effects associated with Cosentyx, an approved treatment for \nankylosing...', 'thumbnail': 'https://serpapi.com/searches/672245d4e92456707116f58a/images/02cee8506acfe07651bff6e0b904559b333935ab18a8f9fd6299890219d2099f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5941896438598633}","{'position': 3, 'link': 'https://ankylosingspondylitisnews.com/2018/06/25/as-therapy-cosentyx-added-public-drug-programs-across-canada/', 'title': 'AS Therapy Cosentyx Added to Public Drug Programs Across Canada', 'source': 'Ankylosing Spondylitis News', 'date': 'Jun 25, 2018', 'snippet': 'Ontario and other regions of Canada will now reimburse Cosentyx \n(secukinumab) under public drug programs for adults with ankylosing...', 'thumbnail': 'https://serpapi.com/searches/672245d4e92456707116f58a/images/02cee8506acfe07657bd8c357c06c314d0f99af43a0476730a84f1517a0161db.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8980309963226318}","{'position': 4, 'link': 'https://ankylosingspondylitisnews.com/2017/11/08/novartis-cosentyx-shows-no-radiographic-progression-in-patients-with-ankylosing-spondylitis/', 'title': 'Little Ankylosing Spondylitis Progression When Using Cosentyx, Data Says', 'source': 'Ankylosing Spondylitis News', 'date': 'Nov 8, 2017', 'snippet': 'Novartis recently reported that long-term radiographic data from a clinical \ntrial showed that treatment of ankylosing spondylitis (AS) with...', 'thumbnail': 'https://serpapi.com/searches/672245d4e92456707116f58a/images/02cee8506acfe0761f447130209b6e917a8db858832d7f794dbce4ef88b0f923.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.890432596206665}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT05955586,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2024/08/05/2924591/0/en/Spero-Therapeutics-Announces-Second-Quarter-2024-Operating-Results-and-Provides-a-Business-Update.html', 'title': 'Spero Therapeutics Announces Second Quarter 2024 Operating Results and Provides a Business Update', 'source': 'GlobeNewswire', 'date': 'Aug 5, 2024', 'snippet': 'Enrollment concluded in the Phase 2a proof-of-concept clinical trial \nevaluating SPR720 in nontuberculous mycobacterial pulmonary disease...', 'thumbnail': 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Results from Phase 2b AHFIRM Trial of Larsucosterol in Alcohol-Associated Hepatitis with Promising Effect on Mortality', 'source': 'PR Newswire', 'date': 'Nov 7, 2023', 'snippet': 'Compelling efficacy signal in favor of larsucosterol in the key secondary \nendpoint of mortality at 90 days. Clinically relevant reduction in...', 'thumbnail': 'https://serpapi.com/searches/6722461fcc48791e95269501/images/f3494c4c1f6834a814877174266c2b7946395c298855265255e0f5fa55b86f40.png', 'sentiment': 'positive', 'sentiment_prob': 0.5870905518531799}","{'position': 2, 'link': 'https://liverdiseasenews.com/news/fda-breakthrough-designation-granted-larsucosterol-hepatitis/', 'title': 'FDA breakthrough designation granted to larsucosterol for AH', 'source': 'liverdiseasenews.com', 'date': 'May 23, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has granted breakthrough therapy \ndesignation to larsucosterol, Durect's investigational therapy for people \nwith..."", 'thumbnail': 'https://serpapi.com/searches/6722461fcc48791e95269501/images/f3494c4c1f6834a8412e34aa8f8aad460874378748dc394699c48932209a22a8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5488607883453369}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT03760146,"{'position': 1, 'link': 'https://www.koreabiomed.com/news/articleView.html?idxno=13140', 'title': 'Pfizer scores European approval for 20-valent pneumococcal vaccine', 'source': 'KBR', 'date': 'Feb 16, 2022', 'snippet': 'Pfizer, which dominated the global pneumococcal vaccine market with \n13-valent Prevnar 13, said it won approval for a 20-valent vaccine in \nEurope.', 'thumbnail': 'https://serpapi.com/searches/672246221397bae56dcc8ea1/images/b00cf21a3bfd37fbf5f3ba32328fe43e187c212eba172cb9cd32393815eab101.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5019819736480713}",,,,,,,,,,['positive'],positive,1 NCT04949841,"{'position': 1, 'link': 'https://finance.yahoo.com/news/leo-pharma-announces-publication-chronic-060000540.html', 'title': 'LEO Pharma Announces Publication of Chronic Hand Eczema Phase 3 Data in The Lancet', 'source': 'Yahoo Finance', 'date': 'Jul 19, 2024', 'snippet': 'The findings of the DELTA 1 and DELTA 2 phase 3 clinical trials for \ndelgocitinib cream have been published in The Lancet.', 'thumbnail': 'https://serpapi.com/searches/672246232da1575f5eaf78b1/images/bc004840436f61a30a54d6f4bed5285c754669532d6e00cf822dff2d1a09f115.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8991910219192505}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20231030388942/en/LEO-Pharma-Announces-Positive-Outcome-of-DELTA-3-Open-Label-Extension-Trial-of-Delgocitinib-Cream-in-the-Treatment-of-Adults-With-Moderate-to-Severe-Chronic-Hand-Eczema-CHE', 'title': 'LEO Pharma Announces Positive Outcome of DELTA 3 Open-Label Extension Trial of Delgocitinib Cream in the Treatment of Adults With Moderate to Severe Chronic Hand Eczema (CHE)', 'source': 'Business Wire', 'date': 'Oct 30, 2023', 'snippet': 'DELTA 3 is a phase 3, single-arm, open-label extension trial of \ndelgocitinib cream, an investigational topical pan-Janus kinase \n(JAK)-inhibitor.', 'thumbnail': 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'Seladelpar eases liver damage, itch in primary biliary cholangitis', 'source': 'liverdiseasenews.com', 'date': 'May 22, 2024', 'snippet': ""One year of treatment with Gilead Sciences' seladelpar normalized \nbiomarkers of liver injury and rapidly reduced itch for most people with \nprimary biliary..."", 'thumbnail': 'https://serpapi.com/searches/6722462c237938d086abc237/images/3f08cb563a3cace91526849e1f949d0156fba45d54095c08b3a6704cd61342bb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7402761578559875}","{'position': 3, 'link': 'https://www.empr.com/news/livdelzi-granted-accelerated-approval-for-primary-biliary-cholangitis/', 'title': 'Livdelzi Granted Accelerated Approval for Primary Biliary Cholangitis', 'source': 'Medical Professionals Reference', 'date': 'Aug 15, 2024', 'snippet': 'The Food and Drug Administration (FDA) has granted accelerated approval to \nLivdelzi (seladelpar) for the treatment of primary biliary cholangitis (PBC)', 'thumbnail': 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Livdelzi for PBC in US', 'source': 'Liver Disease News', 'date': 'Aug 21, 2024', 'snippet': 'Livdelzi, which won FDA approval last week to treat primary biliary \ncholangitis, will be distributed in the U.S. by Orsini and Pantherx...', 'thumbnail': 'https://serpapi.com/searches/6722462c237938d086abc237/images/3f08cb563a3cace97467b1c01400645ac8e1dfc6ff0c3925f45fd71a6be1f444.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8587095141410828}","{'position': 6, 'link': 'https://liverdiseasenews.com/news/fda-approves-gileads-seladelpar-now-livdelzi-treat-pbc-adults/', 'title': 'FDA approves seladelpar, now Livdelzi, to treat adults with PBC', 'source': 'Liver Disease News', 'date': 'Aug 14, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has granted accelerated approval \nto Gilead Sciences' oral candidate seladelpar as a second-line therapy for \nadults..."", 'thumbnail': 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phase 3 and phase 2 clinical trials, Otsuka \nPharmaceutical Co., Ltd. and H. Lundbeck A/S submitted a supplemental...', 'thumbnail': 'https://serpapi.com/searches/672246c3657c66a83b66a8f8/images/4f59873023bf03c108592943440fd5704fb0400602a7ea6896083bf5a1e4b99a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.916138231754303}",,,,,,,,,,['neutral'],neutral,1 NCT03747224,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.15751', 'title': 'Abstract 15751: Pharmacodynamic Effect of ARO-ANG3, an Investigational RNA Interference Targeting Hepatic Angiopoietin-like Protein 3, in Patients With Hypercholesterolemia', 'source': 'American Heart Association Journals', 'date': 'Nov 12, 2020', 'snippet': 'Background: Angiopoietin-like protein 3 (ANGPTL3) regulates triglyceride \n(TG) and lipoprotein (LP) metabolism by inhibiting liver and...', 'thumbnail': 'https://serpapi.com/searches/672243bc316650b50a5d3d89/images/f1b63bb3d334d36b36eaddccffaec4d52f1befbcb9442b888e24fcf17f91eaff.png', 'sentiment': 'neutral', 'sentiment_prob': 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patients in the U.S., developers said at HDSA 2024."", 'thumbnail': 'https://serpapi.com/searches/6722445f740bdba6cefd8b16/images/bd4b353115a8d0f16bb4cc26ca921d8714819f74a7b36e694774a214865d373f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9507646560668945}","{'position': 6, 'link': 'https://huntingtonsdiseasenews.com/news/rg6042-potential-dmt-in-phase-3-trial-named-orphan-drug-in-japan/', 'title': 'RG6042, Potential DMT in Phase 3 Trial, Named Orphan Drug in Japan', 'source': ""Huntington's Disease News"", 'date': 'Mar 5, 2020', 'snippet': 'Japan named RG6042, designed to target all forms of the disease-causing \nmutant huntingtin protein, an orphan drug – a status also given it...', 'thumbnail': 'https://serpapi.com/searches/6722445f740bdba6cefd8b16/images/bd4b353115a8d0f12924ce79bde932ccad50d4671aace892c5bc56917064c793.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.882026195526123}","{'position': 7, 'link': 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Viau. Here's a primer."", 'thumbnail': 'https://serpapi.com/searches/6722445f740bdba6cefd8b16/images/bd4b353115a8d0f1b4834ec71ea0d857eacd5618d8d9dbbfe149c28b088dec9d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9442566633224487}",,,,"['neutral', 'negative', 'negative', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01975701,"{'position': 1, 'link': 'https://www.targetedonc.com/view/present-and-future-precision-medications-signal-promise-for-adults-with-glioma', 'title': 'Present and Future Precision Medications Signal Promise for Adults With Glioma', 'source': 'Targeted Oncology', 'date': 'Feb 4, 2023', 'snippet': 'In an interview with Targeted Oncology, Patrick Wen, MD, discussed \nprecision medicine for adult gliomas, including present and future \ntreatment options.', 'thumbnail': 'https://serpapi.com/searches/672244b67ca6b36e741825b4/images/735ff6a12d4c3a6f2a1877ebbb80ce1b6dec8f1f921c1e418c2550796d87d1b7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.856313169002533}",,,,,,,,,,['neutral'],neutral,1 NCT01915498,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-019-0472-2', 'title': 'Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia', 'source': 'Nature', 'date': 'Apr 9, 2019', 'snippet': 'Older adults with acute myeloid leukemia (AML) who are not fit for standard \nchemotherapy historically have poor outcomes.', 'thumbnail': 'https://serpapi.com/searches/6722453b76079d9baf77d0de/images/7177c9c171c99cec2ca43e4f68d8481a9b0ed74401f79f98dd3853aecd7b0d0f.png', 'sentiment': 'negative', 'sentiment_prob': 0.7587125897407532}",,,,,,,,,,['negative'],negative,0 NCT04186819,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/early/2024/06/13/jnumed.123.267306', 'title': 'Interreader and Intrareader Reproducibility of 18F-Flotufolastat Image Interpretation in Patients with Newly Diagnosed or Recurrent Prostate Cancer: Data from Two Phase 3 Prospective Multicenter Studies', 'source': 'Journal of Nuclear Medicine', 'date': 'Jun 13, 2024', 'snippet': 'Phillip H. Kuo, Giuseppe Esposito, Gary A. Ulaner, Don Yoo, Katherine \nZukotynski, Gregory C. Ravizzini, Ross Penny, Matthew P. Miller,...', 'thumbnail': 'https://serpapi.com/searches/672246f43c9575674df13b60/images/bc4e744662aacaeff64a908f7ce43399f71ec2267f4e73e09e091ac883ae1498.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9256315231323242}","{'position': 2, 'link': 'https://www.itnonline.com/content/blue-earth-diagnostics-highlights-upcoming-presentation-additional-results-investigational', 'title': 'Blue Earth Diagnostics Highlights Upcoming Presentation of Additional Results from Investigational Phase 3 LIGHTHOUSE Study', 'source': 'Imaging Technology News', 'date': 'Feb 9, 2023', 'snippet': 'Results of the Investigational Phase 3 LIGHTHOUSE Study of 18F-rhPSMA-7.3 \nin newly diagnosed prostate cancer to be presented at 2023 ASCO...', 'thumbnail': 'https://serpapi.com/searches/672246f43c9575674df13b60/images/bc4e744662aacaef200fcdbd53be37bc4dc5c10c1e406a1d699ff2b0837cfd10.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9308755993843079}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02064166,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/intranasal-insulin-improve-verbal-fluency-motor-function-parkinsons-multiple-system-atrophy/', 'title': 'Treatment with Intranasal Insulin May Improve Verbal Fluency and Motor Function, Early Study Shows', 'source': ""Parkinson's News Today"", 'date': 'May 2, 2019', 'snippet': ""Treatment with intranasal insulin — which is atomized into a spray and \ninhaled through the nose — may ease Parkinson's disease-related cognitive..."", 'thumbnail': 'https://serpapi.com/searches/672247c7a505f73e63927d8e/images/32d2ad3424c53fc9ecefaf4988477f9a72614cf5614ed3f5fbdf884ceb940c94.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5133353471755981}",,,,,,,,,,['positive'],positive,1 NCT02874742,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-024-01088-6', 'title': 'Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN | Blood Cancer Journal', 'source': 'Nature', 'date': 'Jul 8, 2024', 'snippet': 'The randomized, phase 2 GRIFFIN study (NCT02874742) evaluated daratumumab \nplus lenalidomide/bortezomib/dexamethasone (D-RVd) in...', 'thumbnail': 'https://serpapi.com/searches/67224817c0028ebdd77d3bde/images/d91e1fa696afe9c9814258ac2ccbaf20d519ce566f37bd1b56bbfb44218c28ca.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9279817342758179}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/adding-daratumumab-to-rvd-improves-mrd-negativity-pfs-in-newly-diagnosed-myeloma', 'title': 'Adding Daratumumab to RVd Improves MRD Negativity, PFS in Newly Diagnosed Myeloma', 'source': 'Cancer Network', 'date': 'Jun 5, 2022', 'snippet': 'Daratumumab, lenalidomide, bortezomib and dexamethasone (RVd) outperformed \nRVd alone when it came to minimal residual disease and progression-free \nsurvival.', 'thumbnail': 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'https://www.nature.com/articles/s41408-022-00653-1', 'title': 'Daratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN | Blood Cancer Journal', 'source': 'Nature', 'date': 'Apr 13, 2022', 'snippet': 'We report a post hoc subgroup analysis of the GRIFFIN study examining the \nefficacy and safety of D-RVd in Black patients after all patients completed \n≥12...', 'thumbnail': 'https://serpapi.com/searches/67224817c0028ebdd77d3bde/images/d91e1fa696afe9c931050d7c88973f1e5648c27aff8ccfb75888560ec40568f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8947310447692871}","{'position': 5, 'link': 'https://myelomaresearchnews.com/news/adding-darzalex-to-a-velcade-revlimid-combo-boosts-cancer-disappearance-in-newly-diagnosed-multiple-myeloma-phase-2-trial-shows/', 'title': 'Adding Darzalex to a Velcade-Revlimid Combo Boosts Cancer...', 'source': 'Myeloma Research News', 'date': 'Jul 24, 2019', 'snippet': 'Read about Phase 2 results showing the benefits of adding Darzalex to \ntreatment with Velcade and Revlimid in patients with multiple myeloma.', 'thumbnail': 'https://serpapi.com/searches/67224817c0028ebdd77d3bde/images/d91e1fa696afe9c9fe4fd1a6bedef29467153cb1532bab0f676c15ab3a02826e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5408183336257935}",,,,,,"['neutral', 'neutral', 'positive', 'neutral', 'positive']",neutral,1 NCT04570657,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-parkinsons-disease/', 'title': 'Pipeline Moves: advancement prospects jump for Parkinson’s disease stem cell therapy', 'source': 'Clinical Trials Arena', 'date': 'Mar 21, 2023', 'snippet': 'The Clinical Trials Arena team also review assets in asthma, multiple \noncology indications and blood disorder.', 'thumbnail': 'https://serpapi.com/searches/67224a8b163bdf528ce1d8a9/images/69f12dca28903d1ac0524cb949cd26192c681ee1d5f67fb87a68f05e7ed1cc6c.jpeg', 'sentiment': 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'https://www.empr.com/home/news/drugs-in-the-pipeline/dasiglucagon-under-priority-review-for-hypoglycemia-in-congenital-hyperinsulinism/', 'title': 'Dasiglucagon Gets Priority Review for Hypoglycemia in Congenital Hyperinsulinism', 'source': 'Medical Professionals Reference', 'date': 'Aug 30, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted for Priority Review the \nNew Drug Application (NDA) for dasiglucagon for the prevention...', 'thumbnail': 'https://serpapi.com/searches/672248270d379f2035ac3712/images/80b9e7d9222e258060e9549bc946d4297d8881e90b2dd5a72f63c28d485dcc68.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8679986596107483}","{'position': 2, 'link': 'https://www.globenewswire.com/news-release/2022/05/19/2446817/0/en/Zealand-Pharma-Announces-Positive-Results-from-Phase-3-Trial-of-Dasiglucagon-in-Pediatric-Patients-with-Congenital-Hyperinsulinism-CHI.html', 'title': 'Zealand Pharma Announces Positive Results from Phase 3', 'source': 'GlobeNewswire', 'date': 'May 19, 2022', 'snippet': 'Positive top-line results from its second Phase 3 clinical trial of \ndasiglucagon in pediatric patients with congenital hyperinsulinism (CHI).', 'thumbnail': 'https://serpapi.com/searches/672248270d379f2035ac3712/images/80b9e7d9222e258065b773730a1c58a58f668f188c0e4dd0f71f9ab9c30e4508.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6932388544082642}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04618211,"{'position': 1, 'link': 'https://angioedemanews.com/news/pharvaris-gearing-up-launch-phase-3-trial-phvs416-hae-2024/', 'title': 'Pharvaris aims to launch Phase 3 trial of PHVS416 for HAE in 2024', 'source': 'Angioedema News', 'date': 'Nov 6, 2023', 'snippet': 'Pharvaris is now gearing up startup activities with clinical site \ninvestigators and staff to launch a Phase 3 trial next year of PHVS416.', 'thumbnail': 'https://serpapi.com/searches/67224987272a87d825aec64b/images/c0d225561e5ad69abc069bdaeb90a36cf84e263eb556ab96fcf8d7122d1cce53.png', 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'ResearchGate', 'date': '1 week ago', 'snippet': 'PDF | Disease-modifying treatment strategies for Alzheimer disease (AD) are \nstill under extensive research.', 'thumbnail': 'https://serpapi.com/searches/67224a364677bf469c24a63d/images/6395e69577dc3c7a253576552e5b4964d1b391124624495d89816cbc13620bb5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9267868399620056}",,,,,,,,,,['neutral'],neutral,1 NCT04501679,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2301333', 'title': 'Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis', 'source': 'The New England Journal of Medicine', 'date': 'Oct 25, 2023', 'snippet': 'Prurigo nodularis is a chronic, debilitating, and severely pruritic \nneuroimmunologic skin disease. Nemolizumab, an interleukin-31 receptor...', 'thumbnail': 'https://serpapi.com/searches/67224a465809e724c2f6783d/images/2ed39f667d153329f98f68d22d1f0c390880ad0b94e8a8fd62677bf4829f7b07.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5598675608634949}",,,,,,,,,,['negative'],negative,0 NCT02512068,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/jdi.13126', 'title': 'Efficacy and safety of trelagliptin in Japanese patients with type 2 diabetes with severe renal impairment or end-stage renal disease: Results from a randomized, phase 3 study', 'source': 'Wiley Online Library', 'date': 'Aug 7, 2019', 'snippet': 'Journal of Diabetes Investigation is a clinical and experimental diabetes \nresearch journal publishing basic science, clinical practice,...', 'thumbnail': 'https://serpapi.com/searches/67224bf96ad3c98a9f9436eb/images/be7a7674c389bf23f2bd246cd33baf31cccd27d624f3f25c95054c1135d92a8c.png', 'sentiment': 'neutral', 'sentiment_prob': 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2024', 'snippet': 'Abeona Therapeutics said a mid-cycle meeting with the U.S. Food and Drug \nAdministration was held about its RDEB gene-corrected cell therapy.', 'thumbnail': 'https://serpapi.com/searches/67224d4f8e13c9f929b48ab0/images/b0c485a5820ede289de9ba8d43fe1495873973083573ecd3207595781fb1a4a0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9089530110359192}","{'position': 3, 'link': 'https://epidermolysisbullosanews.com/news/fda-decision-expected-may-pz-cel-cell-therapy-rdeb-was-eb-101/', 'title': 'FDA approval decision expected in May on RDEB cell therapy pz-cel', 'source': 'Epidermolysis Bullosa News', 'date': 'Dec 1, 2023', 'snippet': 'The U.S. Food and Drug Administration (FDA) has granted priority review to \nan application seeking approval of pz-cel (prademagene...', 'thumbnail': 'https://serpapi.com/searches/67224d4f8e13c9f929b48ab0/images/b0c485a5820ede28706519d4f3acb9f8bf2c5909eaa9c380246338661ffcd5a3.png', 'sentiment': 'neutral', 'sentiment_prob': 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'Treatment with telitacicept for almost six months lessened disease activity \nin gMG adults positive for anti-AChR antibodies, per a study.', 'thumbnail': 'https://serpapi.com/searches/67224d8e213c87ebb7b13514/images/81cfbd8c86eb79cc74a1bb38ff31f5b41eda7b9017527a43e9b77758fb91dc69.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7434861660003662}","{'position': 2, 'link': 'https://myastheniagravisnews.com/news/1st-us-patient-enrolled-phase-3-trial-gmg-therapy-telitacicept/', 'title': '1st US patient enrolled in Phase 3 trial of gMG therapy telitacicept', 'source': 'Myasthenia Gravis News', 'date': 'Aug 7, 2024', 'snippet': 'Remegen enrolled the first U.S. patient in a Phase 3 trial testing the \nsafety and efficacy of telitacicept for generalized myasthenia...', 'thumbnail': 'https://serpapi.com/searches/67224d8e213c87ebb7b13514/images/81cfbd8c86eb79ccb90cec275b7e67963d248733923661bc54f86621c10b8124.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9223296046257019}","{'position': 3, 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combination chemotherapy \nregimen consisting of oxaliplatin, irinotecan, fluorouracil,...', 'thumbnail': 'https://serpapi.com/searches/67224da993584c1f1a57b6c8/images/8172c25c325a561fccaea2c18056d49939972bf547e6e8343a09c8ad80ff8e70.png', 'sentiment': 'negative', 'sentiment_prob': 0.5360261797904968}",,,,,,,,,,['negative'],negative,0 NCT01678898,"{'position': 1, 'link': 'https://fabrydiseasenews.com/news/protalix-and-chiesi-get-fda-ok-to-seek-accelerated-approval-of-prx-102-for-fabry-disease/', 'title': 'FDA OKs Plan for Accelerated Approval of Fabry Therapy PRX-102', 'source': 'Fabry Disease News', 'date': 'Nov 27, 2019', 'snippet': 'Investigational Fabry therapy PRX-102 is closer to gainng accelerated \napproval after a successful pre-biologics license application meeting...', 'thumbnail': 'https://serpapi.com/searches/67224e0896a3292c5a248cdc/images/06bff0c0302becd0f4ce99c9c7298abeb5f2565c93270df640f9def7e835f8a3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Nature', 'date': 'Mar 30, 2023', 'snippet': 'This first-in-human placebo-controlled, double-blind, crossover study \ninvestigated the safety (primary objective) and efficacy of oral SB-121.', 'thumbnail': 'https://serpapi.com/searches/67224e902bab902cc6cb9d7e/images/891b9b5bbb8aabbf4dd78703fd1b2e1817d46a56adaa653ec3571866b6e29faf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.917510449886322}",,,,,,,,,,['neutral'],neutral,1 NCT00639639,"{'position': 1, 'link': 'https://www.nature.com/articles/s41420-023-01782-7', 'title': 'Dendritic cell therapy for neurospoagioma: Immunomodulation mediated by tumor vaccine | Cell Death Discovery', 'source': 'Nature', 'date': 'Jan 6, 2024', 'snippet': 'In this review, we summarize the immunomodulatory effects and related \nmechanisms of DC vaccines in neurospoagioma as well as the progress of \nclinical trials.', 'thumbnail': 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and \nhighly selective, allosteric MEK1/2 inhibitor, plus platinum-doublet \nchemotherapy.', 'thumbnail': 'https://serpapi.com/searches/672251476cca5e78b095ff40/images/5d715dbaf7230f2e436f66d597ea8fa4901fa95a59bdf44352238775243b1c84.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8633266091346741}",,,,,,,,,,['neutral'],neutral,1 NCT01526135,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1809775', 'title': 'FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Dec 19, 2018', 'snippet': 'Among patients with metastatic pancreatic cancer, combination chemotherapy \nwith fluorouracil, leucovorin, irinotecan, and oxaliplatin...', 'thumbnail': 'https://serpapi.com/searches/67225158e1c27656915cf583/images/b0dfe77c386ba155c67ec4326d68658f77d95f838a9220ca9f6b06bffbdba831.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8954422473907471}","{'position': 2, 'link': 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peptide at the glucagon receptor \n(GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and \nglucagon-like...', 'thumbnail': 'https://serpapi.com/searches/6722519248c429afe8ebf048/images/bc63ece6fe03bb65feb1c26bd7a433181c4587e10401dd36bb1b71b8f211df22.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7908094525337219}",,,,,,,,,,['neutral'],neutral,1 NCT04372186,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2030340', 'title': 'Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia', 'source': 'The New England Journal of Medicine', 'date': 'Dec 17, 2020', 'snippet': 'Coronavirus disease 2019 (Covid-19) pneumonia is often associated with \nhyperinflammation. Despite the disproportionate incidence of Covid-19...', 'thumbnail': 'https://serpapi.com/searches/6722524adc969f723312e599/images/ef406edc862f93217d83bbf6170abec691928334289a158a9458abc7c10f2967.png', 'sentiment': 'negative', 'sentiment_prob': 0.6772830486297607}",,,,,,,,,,['negative'],negative,0 NCT00048542,"{'position': 1, 'link': 'https://juvenilearthritisnews.com/2020/08/21/humira-shows-long-term-efficacy-safety-in-polyarticular-jia-phase-3-trial/', 'title': 'Humira Shows Long-term Efficacy and Safety in Polyarticular JIA, Phase 3 Trial Reports', 'source': 'Juvenile Arthritis News', 'date': 'Aug 21, 2020', 'snippet': 'Clinical remission was seen in 37% of polyarticular JIA patients given \nHumira for years, and low disease activity in others; 36% finished...', 'thumbnail': 'https://serpapi.com/searches/672253c6d78a989f7c711623/images/6aa724970cd7533aaa277fb5d7613e377c01e99fa27f6f037543fc79d2ad14f5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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NCT02465606,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2206714', 'title': 'Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis', 'source': 'The New England Journal of Medicine', 'date': 'Mar 15, 2023', 'snippet': 'We conducted two identically designed, 52-week, randomized, double-blind, \nplacebo-controlled, phase 3 trials; both trials included a 16-week...', 'thumbnail': 'https://serpapi.com/searches/672254fbd9103905e0e08501/images/36e6007087b82511c1151c1abc2316748a1e2d0d25e7dc0de001e3a277123d6a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8677979707717896}",,,,,,,,,,['neutral'],neutral,1 NCT04128579,"{'position': 1, 'link': 'https://lupusnewstoday.com/news/itolizumab-reduces-urine-protein-levels-phase-1b-clinical-trial/', 'title': 'Itolizumab reduces urine protein levels in Phase 1B clinical trial', 'source': 'Lupus News Today', 'date': 'Apr 8, 2024', 'snippet': 'Treatment with the investigational injection therapy itolizumab \nsignificantly reduced urine protein levels, a marker of kidney dysfunction, \nin people with...', 'thumbnail': 'https://serpapi.com/searches/672255c06f9f6391e098b918/images/ac84764f574f6ecca2edade78e9642bd1a6bc7dc7c203099512c3621dc92e34a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6059826612472534}",,,,,,,,,,['neutral'],neutral,1 NCT01545271,"{'position': 1, 'link': 'https://www.nature.com/articles/pr201549', 'title': 'Adding 5 h delayed xenon to delayed hypothermia treatment improves long-term function in neonatal rats surviving to adulthood', 'source': 'Nature', 'date': 'Mar 11, 2015', 'snippet': 'We previously reported that combining immediate hypothermia with immediate \nor 2 h delayed inhalation of an inert gas, xenon, gave additive...', 'thumbnail': 'https://serpapi.com/searches/6722561b0a545a31f1b8b484/images/c4db627589c5554bea991a2de92b2c8392ada1676a79d51921556f0b6511e30b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7068072557449341}",,,,,,,,,,['neutral'],neutral,1 NCT04117711,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/fda-requests-clinical-outcomes-data-for-galactosemia-treatment/', 'title': 'FDA Requests Clinical Outcomes Data for Galactosemia Treatment', 'source': 'Medical Professionals Reference', 'date': 'Jan 5, 2022', 'snippet': 'Applied Therapeutics announced that it would hold on submitting the New \nDrug Application for AT-007 for the treatment of galactosemia.', 'thumbnail': 'https://serpapi.com/searches/6722569148b9f7c481f5af47/images/335f12a72a8a00ce07ecc317e1b8e5293d55cc0b688371207e2f4b92a139b276.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9303452968597412}",,,,,,,,,,['neutral'],neutral,1 NCT02576717,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/06/30/long-term-data-zeposia-help-cognitive-function-patients/', 'title': 'Long-term Zeposia May Help Cognitive Function in Patients, Data Show', 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 30, 2022', 'snippet': 'Long-term treatment with Zeposia stabilizes or even improves cognitive \nfunction in most adults with relapsing forms of MS, data show.', 'thumbnail': 'https://serpapi.com/searches/6722574666d9958464b7b6ec/images/c8156e7dc525701ce58fda5ca3b601098e10940117c783799779e392a0b3db46.png', 'sentiment': 'positive', 'sentiment_prob': 0.6353581547737122}",,,,,,,,,,['positive'],positive,1 NCT02935790,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-33889-3', 'title': 'HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma | Scientific Reports', 'source': 'Nature', 'date': 'Aug 1, 2023', 'snippet': 'This study identifies HDAC1 and HDAC6 as important and drug-targetable \nenzymes that are necessary for growth and invasiveness in IDH1 mutant \ngliomas.', 'thumbnail': 'https://serpapi.com/searches/672257a4207c885b7cac5e27/images/b23d23e4d31b8b051cde54ead46e5c9adb450efe5807f9757296583179ef5522.png', 'sentiment': 'positive', 'sentiment_prob': 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'Pulmonary Fibrosis News', 'date': 'May 26, 2023', 'snippet': 'BMS-986278 did better than a placebo at slowing lung function decline for \nup to 26 weeks in people with idiopathic pulmonary fibrosis.', 'thumbnail': 'https://serpapi.com/searches/6722586aa471671c163a9db0/images/7aa4eba30459a8bc116b0df4e4b2ad29efbed00178db41fd204a9cd0139d7b3b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6781575083732605}",,,,,,,,,,['neutral'],neutral,1 NCT00545688,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45591-7', 'title': 'Neoadjuvant–adjuvant pertuzumab in HER2-positive early breast cancer: final analysis of the randomized phase III PEONY trial', 'source': 'Nature', 'date': 'Mar 9, 2024', 'snippet': 'The randomized, multicenter, double-blind, placebo-controlled, phase III \nPEONY trial (NCT02586025) demonstrated significantly improved total...', 'thumbnail': 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'Magnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials', 'source': 'Nature', 'date': 'May 21, 2024', 'snippet': 'Pre-clinical and clinical studies have shown that PEGPH20 depletes \nintratumoral hyaluronic acid (HA), which is linked to high interstitial...', 'thumbnail': 'https://serpapi.com/searches/6722593a6ad3c98a6ed71d4c/images/054886bbee314c40e56b6f4c37bc304e193a9e6fbbc3208ccacdd92909168952.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8239365816116333}",,,,,,,,,,['neutral'],neutral,1 NCT02135419,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2201048', 'title': 'Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 15, 2022', 'snippet': 'The incidence of anal cancer is substantially higher among persons living \nwith the human immunodeficiency virus (HIV) than in the general...', 'thumbnail': 'https://serpapi.com/searches/6722593ec0028ebd8f5b8d89/images/1143f046335dbf0e47b27b1e1d750ef32989b116972912b5c8af9c87c8c124d7.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6387670040130615}",,,,,,,,,,['negative'],negative,0 NCT02431468,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/bryostatin-neurotrope-improves-cognition-advanced-alzheimers/', 'title': ""Bryostatin by Neurotrope Improved Cognition in Advanced Alzheimer's"", 'source': ""Alzheimer's News Today"", 'date': 'Mar 21, 2018', 'snippet': ""Learn more about how Bryostatin, an investigational therapy by Neurotrope, \nwas associated with improved cognition in advanced Alzheimer's..."", 'thumbnail': 'https://serpapi.com/searches/67225a074a3fcfceed32877a/images/da550101955a89c373cab9825e6c1b04e9402eadd6707acf59e5abee9e0f4e05.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5256300568580627}",,,,,,,,,,['positive'],positive,1 NCT02648282,"{'position': 1, 'link': 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established a matched pair of glioblastoma stem-like cell \n(GSC) cultures from patient glioblastoma samples before and after epidermal \ngrowth...', 'thumbnail': 'https://serpapi.com/searches/67225a7aba13f21ac0517dc4/images/1c8f6f89acc9adffd39dcd70dcfd31d781772b419014a331291790ebd3c21c7c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8742778897285461}",,,,,,,,,,['neutral'],neutral,1 NCT00127530,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/01/17/acorda-taking-over-global-sales-ampyra-fampyra-ms/', 'title': 'Acorda taking over global sales of Ampyra and Fampyra for MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Jan 17, 2024', 'snippet': 'An agreement with Acorda is ending that had Biogen handle sales of Fampyra, \nas the MS walking aid treatment is known outside the US.', 'thumbnail': 'https://serpapi.com/searches/67225e1f72e5c43d84fcf717/images/05ad9221ef3e7ad612bfeda62d50a23ce7de4f4acc583af8f0ce31f7d12b7368.png', 'sentiment': 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gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (DESTINY-Gastric02): primary and updated analyse', 'source': 'The Lancet', 'date': 'Jun 14, 2023', 'snippet': 'We report primary and updated analyses of the single-arm, phase 2 \nDESTINY-Gastric02 trial, which aimed to examine trastuzumab deruxtecan in \npatients living in...', 'thumbnail': 'https://serpapi.com/searches/67225e78d9c3e6fb8aae1f0a/images/8be07ce3af40b8469a2fda4ff98534888b75104a1f95cecc9e55f6d5974850c5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.878913938999176}",,,,,,,,,,['neutral'],neutral,1 NCT03867123,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02356-1', 'title': 'A Phase 1/2A trial of idroxioleic acid: first-in-class sphingolipid regulator and glioma cell autophagy inducer with antitumor activity in refractory glioma | British Journal of Cancer', 'source': 'Nature', 'date': 'Jul 24, 2023', 'snippet': 'The first-in-class brain-penetrating synthetic hydroxylated lipid \nidroxioleic acid (2-OHOA; sodium 2-hydroxyoleate), activates \nsphingomyelin...', 'thumbnail': 'https://serpapi.com/searches/67225e7fc97e356b10d663a1/images/20d78c0a27fc6d6df1ab6c0ba13e06dc7117cd5903bd58337c5ade54eed09ce7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8801302909851074}",,,,,,,,,,['neutral'],neutral,1 NCT03988608,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-45607-0', 'title': 'Efficacy and safety of eltrombopag in Chinese patients with refractory or relapsed severe aplastic anemia', 'source': 'Nature', 'date': 'Nov 2, 2023', 'snippet': 'This is the first prospective study to show that eltrombopag is efficacious \nand has a favorable safety profile in a Chinese patient population with r/r \nSAA.', 'thumbnail': 'https://serpapi.com/searches/67225f0e9936889d40bd01be/images/359a7805e48b91469082f712531719e4f8fc7476c6fdb261e52d3715fdf885ad.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5287815928459167}",,,,,,,,,,['neutral'],neutral,1 NCT01212952,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/optimismm-trial-shows-benefit-of-pomalyst-combo-for-resistant-mm/', 'title': 'OPTIMISMM Trial Shows Benefit of Pomalyst Combo for Resistant MM', 'source': 'Myeloma Research News', 'date': 'May 31, 2019', 'snippet': 'Pivotal OPTIMISMM trial shows that combining Pomalyst with Velcade and \ndexamethasone can prolong survival of patients with...', 'thumbnail': 'https://serpapi.com/searches/67225c2c642c3145fd3b1bd5/images/0f750b2e65cf5147a8016ac82bb7517ecca935e6a0abe139996496c965d0b666.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6882515549659729}",,,,,,,,,,['positive'],positive,1 NCT05782179,"{'position': 1, 'link': 'https://pf-media.co.uk/news/minervax-begins-phase-1-clinical-study-of-novel-gbs-vaccine/', 'title': 'MinervaX begins phase 1 clinical study of novel GBS vaccine', 'source': 'Pf Media', 'date': 'Apr 17, 2023', 'snippet': 'MinervaX has announced the first phase 1 clinical study in older adults of \nits novel vaccine for Group B Streptococcus.', 'thumbnail': 'https://serpapi.com/searches/67225fe07ca6b31d9b999726/images/6dadcfd6e0e1b953db3e5226ed44a2b4599023ef6a5d5cf471a316cf13d590a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8728817105293274}",,,,,,,,,,['neutral'],neutral,1 NCT01885078,"{'position': 1, 'link': 'https://rheumatoidarthritisnews.com/baricitinib-olumiant-for-rheumatoid-arthritis/', 'title': 'Baricitinib (Olumiant) for Rheumatoid Arthritis', 'source': 'Rheumatoid Arthritis News', 'date': 'Apr 24, 2017', 'snippet': 'Read about Baricitinib (Olumiant), which inhibits the inflammation \nassociated with rheumatoid arthritis, easing the joint pain that stems from \nthe disease.', 'thumbnail': 'https://serpapi.com/searches/67225fec7ac731301bf5e382/images/8209b323ac00ad1f011e11cc4e51e55836b6a4237800f48d63a0b5a24305d024.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'source': 'The New England Journal of Medicine', 'date': 'Sep 19, 2019', 'snippet': 'In patients with type 2 diabetes, inhibitors of sodium–glucose \ncotransporter 2 (SGLT2) reduce the risk of a first hospitalization for \nheart failure,...', 'thumbnail': 'https://serpapi.com/searches/6722609dc4bcf53569db5d02/images/97355a20fe5b27f505d46bde8821742497cd7c617c89217e960620983e36cd0b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7701650261878967}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.044133', 'title': 'Efficacy and Safety of Dapagliflozin in Heart Failure With Reduced Ejection Fraction According to Age | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 17, 2019', 'snippet': 'Background:The DAPA-HF trial (Dapagliflozin and Prevention of \nAdverse-Outcomes in Heart Failure) showed that dapagliflozin added to \nother...', 'thumbnail': 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'https://www.businesswire.com/news/home/20200218005144/en/Five-Prime-Therapeutics-Provides-Update-on-Phase-2-Trial-of-Cabiralizumab-Combined-with-Opdivo%C2%AE-in-Pancreatic-Cancer', 'title': 'Five Prime Therapeutics Provides Update on Phase 2 Trial of Cabiralizumab Combined with Opdivo', 'source': 'Business Wire', 'date': 'Feb 18, 2020', 'snippet': 'SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Five Prime Therapeutics, Inc. \n(NASDAQ: FPRX), a clinical-stage biotechnology company focused...', 'thumbnail': 'https://serpapi.com/searches/672260c2361fd48e0c18cf6f/images/985c49bc23a5595e30adc83234f88819f6ba0a5d93d5b1abe48ed21b33e90596.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8890454769134521}",,,,,,,,,,['neutral'],neutral,1 NCT02501096,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.19.02627', 'title': 'Lenvatinib Plus Pembrolizumab in Patients With Advanced Endometrial Cancer', 'source': 'ASCO Publications', 'date': 'Mar 13, 2020', 'snippet': 'PURPOSEPatients with advanced endometrial carcinoma have limited treatment \noptions. 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analysis of the randomised phase 3 LUX-Lung 8 trial', 'source': 'The Lancet', 'date': 'Jun 17, 2021', 'snippet': 'LUX-Lung 8 was a randomised, controlled, phase 3 study comparing afatinib \nand erlotinib as second-line treatment of patients with advanced squamous \ncell...', 'thumbnail': 'https://serpapi.com/searches/67226e948db376c3934f4181/images/0177f462cc2ec047e8bcf4996fc9fef17504c8a2725f9ee69d73041cd2cbd228.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9027174115180969}",,,,,,,,,,['neutral'],neutral,1 NCT03734016,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2211582', 'title': 'Zanubrutinib or Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Dec 13, 2022', 'snippet': ""In a multinational, phase 3, head-to-head trial, ibrutinib, a Bruton's \ntyrosine kinase (BTK) inhibitor, was compared with zanubrutinib,..."", 'thumbnail': 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Unfortunately, it was unsuccessful due to side effects...', 'thumbnail': 'https://serpapi.com/searches/67226ff88d147392a7c2f125/images/d862b3ea53f132d16e483f169aaf04368d0d6ab93a11e096d582e14d0e10ebe3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5593463778495789}",,,,,,,,,,['neutral'],neutral,1 NCT03050879,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-42712-6', 'title': 'Indocyanine green fluorescence imaging-guided versus conventional laparoscopic lymphadenectomy for gastric cancer: long-term outcomes of a phase 3 randomised clinical trial', 'source': 'Nature', 'date': 'Nov 16, 2023', 'snippet': 'Indocyanine green (ICG) fluorescence imaging-guided lymphadenectomy has \nbeen demonstrated to be effective in increasing the number of lymph...', 'thumbnail': 'https://serpapi.com/searches/67227074a86921c0f30b9d38/images/809f79110503ed0e82646f7ad0226324a1a1ae3e4b2deb2f606866a97640071a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9205148816108704}",,,,,,,,,,['neutral'],neutral,1 NCT05149313,"{'position': 1, 'link': 'https://www.contemporarypediatrics.com/view/bla-resubmitted-for-lebrikizumab-to-treat-ad-patients-12-years-and-up', 'title': 'BLA resubmitted for lebrikizumab to treat AD patients 12 years and up', 'source': 'Contemporary Pediatrics', 'date': 'Apr 30, 2024', 'snippet': 'Eli Lilly and Company has resubmitted a Biologic License Application (BLA) \nfor the treatment of moderate-to-severe atopic dermatitis (AD) in adults \nand...', 'thumbnail': 'https://serpapi.com/searches/6722707a6273fbad5367f8d1/images/7209fb4cb41e103a8cc63c74859b7929330b22424109c3e929cf2a4d956e9994.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8648383021354675}",,,,,,,,,,['neutral'],neutral,1 NCT03214250,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01829-9', 'title': 'Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial', 'source': 'Nature', 'date': 'Jun 3, 2022', 'snippet': 'Chemotherapy combined with immunotherapy has improved the treatment of \ncertain solid tumors, but effective regimens remain elusive for...', 'thumbnail': 'https://serpapi.com/searches/672270837c1712784f806358/images/4b0fbe1f40dcbcba51607794a46f43fae21be432eb1c1e55089602bc0a842a23.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8624395728111267}",,,,,,,,,,['neutral'],neutral,1 NCT03307148,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-020-18636-w', 'title': 'Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer', 'source': 'Nature', 'date': 'Sep 24, 2020', 'snippet': 'Pre-clinical models have shown that targeting pancreatic stellate cells \nwith all-trans-retinoic-acid (ATRA) reprograms pancreatic stroma to...', 'thumbnail': 'https://serpapi.com/searches/672271854791c4eceb2e3f6c/images/7aed216d781837bb52f950be30f54e7fa0da07659aa6251a8601069d41f072bb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9115622639656067}","{'position': 2, 'link': 'https://www.nature.com/articles/s41698-021-00192-1', 'title': 'Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma | npj Precision Oncology', 'source': 'Nature', 'date': 'Jun 29, 2021', 'snippet': 'PTX3 is a putative stromally-derived biomarker for PDAC which warrants \nfurther testing in prospective, larger, multi-center cohorts and within \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/672271854791c4eceb2e3f6c/images/7aed216d781837bb6aa50c0e7bb15aa9d5cbe761cdd88295316b036382f793bf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9184646606445312}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02094053,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/dmcn.15517', 'title': 'State‐of‐the‐art therapy for Down syndrome - Lorenzon - 2023 - Developmental Medicine & Child Neurology', 'source': 'Wiley Online Library', 'date': 'Jan 24, 2023', 'snippet': 'This review covers five key areas: (1) What has happened in the last 10 \nyears? (2) From symptomatic to disease-modifying therapy:...', 'thumbnail': 'https://serpapi.com/searches/672271daf6aa53bdaefae4b1/images/aae44a77737dd1e1bf0daa96d11346714cbf23752304ffd0a828a1aea83c5b7b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9450766444206238}",,,,,,,,,,['neutral'],neutral,1 NCT00204516,"{'position': 1, 'link': 'https://www.nature.com/articles/s41587-022-01294-2', 'title': 'The clinical progress of mRNA vaccines and immunotherapies', 'source': 'Nature', 'date': 'May 9, 2022', 'snippet': 'The emergency use authorizations (EUAs) of two mRNA-based severe acute \nrespiratory syndrome coronavirus (SARS-CoV)-2 vaccines approximately...', 'thumbnail': 'https://serpapi.com/searches/67227240a882788f7cdd1988/images/d3466bca219e1e6346d0b0b741dcbb11f97e22eb9b07d581d092184a08baf632.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921474814414978}",,,,,,,,,,['neutral'],neutral,1 NCT04200248,"{'position': 1, 'link': 'https://www.nature.com/articles/s41433-023-02848-7', 'title': 'Clinical proof of concept for anti-FGF2 therapy in exudative age-related macular degeneration (nAMD): phase 2 trials in treatment-naïve and anti-VEGF pretreated patients | Eye', 'source': 'Nature', 'date': 'Nov 30, 2023', 'snippet': 'Intravitreal injections of anti-vascular endothelial growth factor (VEGF) \nagents are the first-line treatment for exudative age-related...', 'thumbnail': 'https://serpapi.com/searches/67227281a2510461cc6c57f8/images/d312448570e6742ee5000c6a4231b917d6ca10e170e633abfcc531de19955055.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8916304111480713}",,,,,,,,,,['neutral'],neutral,1 NCT03288324,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.655100/full', 'title': ""What's New in the Treatment of Systemic Lupus Erythematosus"", 'source': 'Frontiers', 'date': 'Mar 5, 2021', 'snippet': 'The aim of this review is to summarize data on SLE treatment that have \nemerged over the last 3 years. We will put emphasis on studies evaluating \npotential...', 'thumbnail': 'https://serpapi.com/searches/67227312b5ecbb099a1b2dd2/images/434d3895567fc63e0baff2a8d817cbd94aee78fa9d9288cd8e7a1ba94f448c56.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9232494831085205}",,,,,,,,,,['neutral'],neutral,1 NCT03461211,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1910434', 'title': 'Teprotumumab for the Treatment of Active Thyroid Eye Disease', 'source': 'The New England Journal of Medicine', 'date': 'Jan 22, 2020', 'snippet': 'Teprotumumab resulted in better outcomes with respect to proptosis, \nClinical Activity Score, diplopia, and quality of life than placebo; \nserious adverse events...', 'thumbnail': 'https://serpapi.com/searches/67227330fc40bfd05b717980/images/b87e8384e6138f478577e7b2f9e833afae945e2d1069ca0768f37898cff7c27f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4944324493408203}",,,,,,,,,,['neutral'],neutral,1 NCT00466583,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2023.1082057/full', 'title': 'The hypoxia-inducible factor-1α in stemness and resistance to chemotherapy in gastric cancer: Future directions for therapeutic targeting', 'source': 'Frontiers', 'date': 'Feb 8, 2023', 'snippet': 'Hypoxia-inducible factor-1α (HIF-1α) is a crucial mediator of intra-tumoral \nheterogeneity, tumor progression, and unresponsiveness to...', 'thumbnail': 'https://serpapi.com/searches/672274268f2bc20cba223b79/images/0e733e721127813ff6d4a8f81b2b06d8e028cae959ce9e561f2dd188cdc69bae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.679175615310669}",,,,,,,,,,['neutral'],neutral,1 NCT01848639,"{'position': 1, 'link': 'https://www.springermedizin.de/mineralocorticoid-receptor-overactivation-targeting-systemic-imp/26555368', 'title': 'Mineralocorticoid receptor overactivation: targeting systemic impact with non-steroidal mineralocorticoid receptor antagonists', 'source': 'springermedizin.de', 'date': 'Dec 22, 2023', 'snippet': 'The overactivation of the mineralocorticoid receptor (MR) promotes \npathophysiological processes related to multiple physiological systems, \nincluding.', 'thumbnail': 'https://serpapi.com/searches/67227439b6a79c89e80b7eca/images/c83ffed3da4c3484dad03d415de255f1cf3333a8a9ef7716ac6ca79cca77dd56.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7335309982299805}",,,,,,,,,,['neutral'],neutral,1 NCT02411253,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-34162-3', 'title': 'Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes', 'source': 'Nature', 'date': 'Nov 28, 2022', 'snippet': 'Despite early clinical successes, the mechanisms of action of low-dose \ninterleukin-2 (LD-IL-2) immunotherapy remain only partly understood.', 'thumbnail': 'https://serpapi.com/searches/67227457fc40bfd05b717a7e/images/f0c61b6a774b0481c9c41acde0825014bb570297124b093d9a7b73d511eb4066.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.66771000623703}",,,,,,,,,,['neutral'],neutral,1 NCT01073865,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/nccn-guidelines-support-goserelin-for-ovarian-suppression-in-breast-cancer', 'title': 'NCCN Guidelines Support Goserelin for Ovarian Suppression in Breast Cancer', 'source': 'Cancer Network', 'date': 'Feb 17, 2024', 'snippet': 'The National Comprehensive Cancer Network has issued a category 2A \nrecommendation for the use of goserelin for ovarian function suppression...', 'thumbnail': 'https://serpapi.com/searches/672274d32bab90dba326aad1/images/c0bc80c49e32cf7a3ba2b712d19d94fe7a52467091ae431963e701249f0a7718.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9110586643218994}",,,,,,,,,,['neutral'],neutral,1 NCT03090100,"{'position': 1, 'link': 'https://psoriasisnewstoday.com/2017/05/25/janssens-phase-3-trials-on-guselkumab-for-plaque-psoriasis-and-psoriatic-arthritis/', 'title': 'Janssen’s Phase 3 Trials for Guselkumab to Focus on Plaque Psoriasis, Psoriatic Arthritis', 'source': 'Psoriasis News Today', 'date': 'May 25, 2017', 'snippet': 'Janssen announced two new Phase 3 clinical trials for psoriasis for its \ninvestigational drug guselkumab. The company intends to explore the...', 'thumbnail': 'https://serpapi.com/searches/6722754adc969f1f112023a4/images/575361c5a3dd0ee91148d670251f13b1cb805194ff243b0ee5a90e3f376b5f52.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9209516644477844}",,,,,,,,,,['neutral'],neutral,1 NCT00731263,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Graph-of-effect-of-gastric-pH-on-the-cumulative-appearance-of-AZD8055-in-jejunal-and_fig3_221870360', 'title': 'Fig. 3. Graph of effect of gastric pH on the cumulative appearance of...', 'source': 'ResearchGate', 'date': 'Mar 9, 2018', 'snippet': 'Download scientific diagram | Graph of effect of gastric pH on the \ncumulative appearance of AZD8055 in jejunal and ileal fi ltrates versus \ntime after dosing...', 'thumbnail': 'https://serpapi.com/searches/6722759711db450186c6e55b/images/ce5acc81792df7dc74aa06aaa679c227fef33ea92624329ef6a561dbb91c76b4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9149064421653748}",,,,,,,,,,['neutral'],neutral,1 NCT05925114,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/alnylam-win-amvuttra-attr-amyloidosis/', 'title': 'Pipeline Moves: Alnylam’s Amvuttra approval prospects up after Phase III win', 'source': 'Clinical Trials Arena', 'date': 'Jul 8, 2024', 'snippet': 'The Clinical Trials Arena team also investigates candidates in metabolic \ndisorders, oncology and central nervous system.', 'thumbnail': 'https://serpapi.com/searches/672275a2642c31fec49cd484/images/506f80fb4777ff8a06ffc75778567eabec9565dff5d3bb2619c39bcbffb55e80.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5443851947784424}",,,,,,,,,,['positive'],positive,1 NCT02864147,"{'position': 1, 'link': 'https://medicine.yale.edu/profile/masoud-azodi/', 'title': 'Masoud Azodi, MD', 'source': 'Yale School of Medicine', 'date': 'Nov 14, 2022', 'snippet': 'Dr. Azodi is board certified in both Ob/Gyn and in Gynecologic Oncology. He \ntreats all gynecologic cancers and pre-cancers using numerous therapies.', 'thumbnail': 'https://serpapi.com/searches/67227616fbde0d1847a33cfa/images/504e7a3b7762a437e262b7eb16f647e241cb149726e7c22353ba967bfe25c6a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.626664936542511}","{'position': 2, 'link': 'https://medicine.yale.edu/profile/mitchell-clark/', 'title': 'Mitchell Clark, MD, MPH', 'source': 'Yale School of Medicine', 'date': 'Nov 14, 2022', 'snippet': 'Dr. Clark holds the rank of assistant professor of Obstetrics and \nGynecology in the Division of Gynecologic Oncology at Yale University \nSchool of Medicine.', 'thumbnail': 'https://serpapi.com/searches/67227616fbde0d1847a33cfa/images/504e7a3b7762a43735f94ce1a95215de6207849a6dc7ad3992dda296637cf950.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8801649808883667}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02852655,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-24293-4', 'title': 'Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1', 'source': 'Nature', 'date': 'Jun 29, 2021', 'snippet': 'The response of patients with recurrent glioblastoma multiforme to \nneoadjuvant immune checkpoint blockade has been challenging to interpret...', 'thumbnail': 'https://serpapi.com/searches/67227622e95dbf88bcceeaae/images/4c518f2558cc3b0bae97e5cadfa43e678e32dfc9ad961ca9792408dec5ee1fd4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.763203501701355}",,,,,,,,,,['neutral'],neutral,1 NCT04819854,"{'position': 1, 'link': 'https://copdnewstoday.com/news/fda-oks-phase-2-clinical-trial-ep395-copd-patients/', 'title': 'FDA OKs Phase 2 Clinical Trial of EP395 for COPD Patients', 'source': 'COPD News Today', 'date': 'Nov 28, 2022', 'snippet': 'The US Food and Drug Administration (FDA) has authorized EpiEndo \nPharmaceuticals to conduct a Phase 2a clinical trial of its antibiotic \ntreatment EP395 in...', 'thumbnail': 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Hemophilia A without Inhibitors', 'source': 'The New England Journal of Medicine', 'date': 'Aug 29, 2018', 'snippet': 'Emicizumab prophylaxis administered subcutaneously once weekly or every 2 \nweeks led to a significantly lower bleeding rate than no prophylaxis among \npersons...', 'thumbnail': 'https://serpapi.com/searches/672276f25ed3cab1ee1bad54/images/9d14c8a7629df52de1383bd2d2bf059c5aabdc5760af6695b65d476735b33ae1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7872651219367981}","{'position': 2, 'link': 'https://hemophilianewstoday.com/news/in-trial-hemlibra-improves-joint-health-younger-hem-a-patients-hemophilia-a-treatment/', 'title': 'In Trial, Hemlibra Improves Joint Health for Younger Hem A Patients', 'source': 'Hemophilia News Today', 'date': 'Aug 19, 2022', 'snippet': 'Treatment with Hemlibra (emicizumab) improved joint health for people with \nhemophilia A in the HAVEN 3 clinical trial, a study finds.', 'thumbnail': 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'snippet': 'Concomitant antiplatelet use in anticoagulated patients undergoing device \nsurgery is associated with a 2-fold increase in the risk of clinically \nsignificant...', 'thumbnail': 'https://serpapi.com/searches/67227b4b5c7cb9ea52f7c947/images/76f26187150b7bbe5544f74980a5fe4cac9b7ea1a51e612166761fb6fdd78335.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5843335390090942}",,,,,,,,,,['neutral'],neutral,1 NCT05021484,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2400763', 'title': 'A Randomized Phase 2 Trial of Felzartamab in Antibody-Mediated Rejection', 'source': 'The New England Journal of Medicine', 'date': 'May 25, 2024', 'snippet': 'We conducted a phase 2, randomized, double-blind, placebo-controlled trial \nto evaluate the safety, side-effect profile, and preliminary efficacy of \nfelzartamab', 'thumbnail': 'https://serpapi.com/searches/67227bb381bab7385d2609ad/images/f3950e0841dd035a3883b8829bcdfc4d71ee6370ea5be672503fc14fd25f8003.jpeg', 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'StockWatch: Neurocrine Tumbles as Schizophrenia Data Disappoints', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Aug 29, 2024', 'snippet': ""According to results trumpeted by Neurocine from the Phase II \nNBI-1117568-SCZ2028 trial (NCT05545111), a once daily, 20 mg dose of '568..."", 'thumbnail': 'https://serpapi.com/searches/67227cb364f11d789995ce38/images/b131307cc928cd8251b790ae82268237739093b8729a01acce8750cfcea48594.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5235870480537415}",,,,,,,,,,['negative'],negative,0 NCT04285827,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/csl889-designated-orphan-drug-europe-and-us-treating-sickle-cell-disease/', 'title': 'CSL889 Designated as Orphan Drug in Europe and US for Treating...', 'source': 'Sickle Cell Disease News', 'date': 'Nov 5, 2020', 'snippet': 'The European Commission and the FDA have granted orphan drug status to \nCSL889, an investigational therapy for sickle cell disease.', 'thumbnail': 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For patients who responded to their first treatment,...', 'thumbnail': 'https://serpapi.com/searches/67228767069e577c45983a7a/images/2d664236304e80fd076b02af13dedb5fabf6c09c4751d11ffac565fbbd86f16d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5939822196960449}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01785602,"{'position': 1, 'link': 'https://www.researchgate.net/figure/An-overview-of-the-pathogenesis-of-atopic-dermatitis-on-the-skin-Emerging-drugs-and_fig1_334806931', 'title': 'Fig. 1 An overview of the pathogenesis of atopic dermatitis on the...', 'source': 'ResearchGate', 'date': 'Feb 20, 2020', 'snippet': 'Atopic dermatitis (AD) is a chronic, inflammatory skin disease \ncharacterized by pruritus, inflammatory erythematous skin lesions, and \nskin-barrier defect.', 'thumbnail': 'https://serpapi.com/searches/672287710be2f63ada29c0af/images/feb1c50773f1049bca1f599f44d0bc82c9eef4e06f279ea0a69267bbb98c801c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Sanofi’s Next-generation ERT Halts Progression of Pompe Disease in Patients, Interim Trial Data Show', 'source': 'Pompe Disease News', 'date': 'Feb 13, 2020', 'snippet': ""Sanofi Genzyme's avalglucosidase alfa safely halts disease progression in \npeople with Pompe disease, according to interim data from two..."", 'thumbnail': 'https://serpapi.com/searches/672288a864f11d789995d8fd/images/380729bf14ca18da17bd81c715898c30fa71fa328be314b1bf610a9296439612.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8510002493858337}",,,,,,,,,,['neutral'],neutral,1 NCT02389842,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-29425-y', 'title': 'Targeting mTOR to overcome resistance to hormone and CDK4/6 inhibitors in ER-positive breast cancer models', 'source': 'Nature', 'date': 'Feb 15, 2023', 'snippet': 'Our results revealed that mTOR inhibition is more effective than PI3K \ninhibition in overcoming resistance, irrespective of PIK3CA mutation status.', 'thumbnail': 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low-density...', 'thumbnail': 'https://serpapi.com/searches/67228a6216779391e19a23c6/images/ca32998ec34335723d17d1308ff628f80f35cd3de98133fb3877212ebe99a282.png', 'sentiment': 'neutral', 'sentiment_prob': 0.796350359916687}",,,,,,,,,,['neutral'],neutral,1 NCT03098797,"{'position': 1, 'link': 'https://www.yahoo.com/finance/news/fda-adcom-votes-favour-stealth-173237365.html', 'title': 'FDA AdCom votes in favour of Stealth’s Barth syndrome drug', 'source': 'Yahoo', 'date': '3 weeks ago', 'snippet': ""The Cardiovascular and Renal Drugs Advisory Committee voted 10-6 in support \nof Stealth's elamipretide for the ultra-rare disorder."", 'thumbnail': 'https://serpapi.com/searches/67228a6624296aed45f1105f/images/538fd29451342ecba9a3215580a6d2208be71591680692c216427bc0014014d4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7460616230964661}","{'position': 2, 'link': 'https://mitochondrialdiseasenews.com/2017/07/26/trial-elamipretide-treatment-barth-syndrome-started/', 'title': 'Potential Barth Syndrome Therapy, Elamipretide, to Be Tested in Clinical Trial', 'source': 'Mitochondrial Disease News', 'date': 'Jul 26, 2017', 'snippet': 'A Phase 2/3 clinical trial of elamipretide, a potential treatment for a \nrare mitochondrial disease known as Barth syndrome, is now enrolling \npatients.', 'thumbnail': 'https://serpapi.com/searches/67228a6624296aed45f1105f/images/538fd29451342ecbf8e5444eb88dcbd43ad3c931612a1c56680135ba3d9fbcae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9102270603179932}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05493995,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-024-01857-6', 'title': 'First-line penpulimab (an anti-PD1 antibody) and anlotinib (an angiogenesis inhibitor) with nab-paclitaxel/gemcitabine (PAAG) in metastatic pancreatic cancer: a prospective, multicentre, biomolecular exploratory, phase II trial | Signal Transduction and Targete', 'source': 'Nature', 'date': 'Jun 7, 2024', 'snippet': 'Metastatic pancreatic cancer (mPC) has a dismal prognosis. Herein, we \nconducted a prospective, multicentre, single-arm, phase II trial...', 'thumbnail': 'https://serpapi.com/searches/67228af93c944b0711a261c4/images/8fb99c4d8bc72e1060a039101a2b072eb47b4ad5fbbf3b0139154ff2b9b05d24.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5156915187835693}",,,,,,,,,,['neutral'],neutral,1 NCT00158600,"{'position': 1, 'link': 'https://pompediseasenews.com/lumizyme-alglucosidase-alfa-for-the-treatment-of-pompe-disease/', 'title': 'Lumizyme (Alglucosidase Alfa) in Pompe Disease', 'source': 'Pompe Disease News', 'date': 'Jul 15, 2022', 'snippet': 'Lumizyme (alglucosidase alfa) is an enzyme replacement therapy for Pompe \ndisease. Learn about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/67228ba0671f3fe9cb229d8c/images/b65cdf54e08878770b193d4d71c91a715012e4b48b53948d7e5b85ef76b35b29.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8790404200553894}",,,,,,,,,,['neutral'],neutral,1 NCT02172950,"{'position': 1, 'link': 'https://hemophilianewstoday.com/afstyla-for-hemophilia-a/', 'title': 'Afstyla (lonoctocog alfa) for hemophilia', 'source': 'Hemophilia News Today', 'date': 'Nov 15, 2023', 'snippet': 'Afstyla is an injectable factor replacement therapy used to prevent and \ntreat bleeding episodes in hemophilia A patients.', 'thumbnail': 'https://serpapi.com/searches/67228ed12e33c8a68aaec5b7/images/6364eb787bb242b944a5e88ed02d18d1a76a430dae2099b6f611225a5837230f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8757435083389282}",,,,,,,,,,['neutral'],neutral,1 NCT02510794,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20170619005283/en/Vital-Art-and-Science-Announces-License-Agreement-with-Genentech-for-Its-mVT%C2%AE-Service', 'title': 'Vital Art and Science Announces License Agreement with Genentech for Its mVT® Service', 'source': 'Business Wire', 'date': 'Jun 19, 2017', 'snippet': 'Vital Art and Science, LLC today announced that it has signed a license \nagreement with Genentech, a member of the Roche Group, for the use of Vital \nArt and...', 'thumbnail': 'https://serpapi.com/searches/67228f0ff60b6f07ae86a45e/images/da30b8ea1d5e89c66ffd23ab39a58d85795a3c0e0bf768e57fb99c3bafb3c770.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8740266561508179}",,,,,,,,,,['neutral'],neutral,1 NCT02626364,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2023.1325214/full', 'title': 'Characterization of prevalent tyrosine kinase inhibitors and their challenges in glioblastoma treatment', 'source': 'Frontiers', 'date': 'Jun 25, 2024', 'snippet': 'Glioblastoma multiforme (GBM) is a highly aggressive malignant primary \ntumor in the central nervous system. Despite extensive efforts in \nradiotherapy,...', 'thumbnail': 'https://serpapi.com/searches/67228f7ebe80133871043e7e/images/1f978b6735e2ffed48b67f2e875c34943b1faf6dbfff1d66f47ee2cdff591b3c.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5473702549934387}",,,,,,,,,,['negative'],negative,0 NCT00004031,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1301077', 'title': ""Autologous Transplantation as Consolidation for Aggressive Non-Hodgkin's Lymphoma"", 'source': 'The New England Journal of Medicine', 'date': 'Oct 31, 2013', 'snippet': 'Early autologous stem-cell transplantation improved progression-free \nsurvival among patients with high-intermediate-risk or high-risk disease.', 'thumbnail': 'https://serpapi.com/searches/67228c2eb4b72d6f8cf4b4ff/images/926d9cea5e55be0517a1d5a45ed25198d29e9bba6c8343dfaddd129410a70044.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7844066619873047}",,,,,,,,,,['neutral'],neutral,1 NCT00329628,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0800374', 'title': 'Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty', 'source': 'The New England Journal of Medicine', 'date': 'Jun 26, 2008', 'snippet': 'This phase 3 trial compared the efficacy and safety of rivaroxaban, an oral \ndirect inhibitor of factor Xa, with those of enoxaparin for...', 'thumbnail': 'https://serpapi.com/searches/67228c6de50bc07d7714ea31/images/b3d64155f55c07e7fa1fbc00b05d8b05953b088b7457f220450942b6cab88053.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8526756763458252}",,,,,,,,,,['neutral'],neutral,1 NCT04360434,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2303765', 'title': 'Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid', 'source': 'The New England Journal of Medicine', 'date': 'May 20, 2023', 'snippet': 'NI006 is a recombinant human anti-ATTR antibody that was developed for the \nremoval of ATTR by phagocytic immune cells.', 'thumbnail': 'https://serpapi.com/searches/67228c75be324f0a655783b2/images/9514ec35aedfcb3cf65f07318df4c0b1dc6b687dcb8e76469ea3aa9539f7bedd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9107809662818909}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1073503/full', 'title': 'Changing paradigm in the treatment of amyloidosis: From disease-modifying drugs to anti-fibril therapy', 'source': 'Frontiers', 'date': 'Dec 19, 2022', 'snippet': 'Cardiac amyloidosis is a rare, debilitating, and usually fatal disease \nincreasingly recognized in clinical practice despite patients...', 'thumbnail': 'https://serpapi.com/searches/67228c75be324f0a655783b2/images/9514ec35aedfcb3c4bd6495b01ec8a0f0d27c8f6f8387a89b37b209f44246734.png', 'sentiment': 'negative', 'sentiment_prob': 0.6490713953971863}","{'position': 3, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-phase-iii-oncology-trial-failure/', 'title': 'Pipeline Moves: Prospects drop after Phase III ovarian cancer trial failure', 'source': 'Clinical Trials Arena', 'date': 'Nov 13, 2023', 'snippet': 'The Clinical Trials Arena team also review assets in oncology, infectious \ndiseases and cardiology.', 'thumbnail': 'https://serpapi.com/searches/67228c75be324f0a655783b2/images/9514ec35aedfcb3c0a1abcb8d35bc76d65ab2d959afe4d77e449a69df4bcfcff.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6975389719009399}",,,,,,,,"['neutral', 'negative', 'negative']",negative,0 NCT00799617,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1506119', 'title': 'Effects of Testosterone Treatment in Older Men', 'source': 'The New England Journal of Medicine', 'date': 'Feb 18, 2016', 'snippet': 'Serum testosterone concentrations decrease as men age, but benefits of \nraising testosterone levels in older men have not been established.', 'thumbnail': 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Additional Efficacy Data from Chronic Hand Eczema Phase 2b Trial of Oral SYK/JAK Inhibitor Gusacitinib at AAD VMX Late-Breaking Session', 'source': 'National Eczema Association', 'date': 'Apr 22, 2021', 'snippet': 'The results of this trial are very impressive and provide evidence that \ngusacitinib may be an effective once-daily, oral treatment option for CHE \npatients.', 'thumbnail': 'https://serpapi.com/searches/67228d6ef93388d03dc82e1e/images/5ddd239ea00c2db64b1814c5f66447e088a6e31175b46bc1e166c34463d2416e.png', 'sentiment': 'positive', 'sentiment_prob': 0.6924538612365723}",,,,,,,,,,['positive'],positive,1 NCT02760472,"{'position': 1, 'link': 'https://www.nature.com/articles/s41390-022-02134-4', 'title': 'Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants', 'source': 'Nature', 'date': 'Jun 9, 2022', 'snippet': 'Growth factors important for normal brain development are low in preterm \ninfants. This study investigated the link between growth factors...', 'thumbnail': 'https://serpapi.com/searches/6722924252a04e2f12614cf8/images/bf78def8e216645beb4a7f20db25f13244cf72c635749d43efa156e40300d7a5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7522196173667908}",,,,,,,,,,['neutral'],neutral,1 NCT02108652,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/fda-grants-atezolizumab-accelerated-approval-for-bladder-cancer/', 'title': 'FDA Grants Atezolizumab Accelerated Approval for Bladder Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Apr 18, 2017', 'snippet': 'The US Food and Drug Administration (FDA) has granted the PD-L1-targeting \nmonoclonal antibody atezolizumab (Tecentriq) accelerated approval for \nfirst-line...', 'thumbnail': 'https://serpapi.com/searches/672293300c08f282b39198c0/images/1cdce7b7855a6fc9568148ccea17f8eb0292c262ff30cae98c0465947f4b486b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8297524452209473}",,,,,,,,,,['neutral'],neutral,1 NCT03115112,"{'position': 1, 'link': 'https://www.empr.com/home/news/brenzavvy-approved-for-adults-with-type-2-diabetes/', 'title': 'Brenzavvy Approved for Adults With Type 2 Diabetes', 'source': 'Medical Professionals Reference', 'date': 'Jan 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Brenzavvy™ \n(bexagliflozin) as an adjunct to diet and exercise to improve glycemic...', 'thumbnail': 'https://serpapi.com/searches/6722949e9e5bd5d95e2ec68d/images/f0d0f200f625b349596006cd1740756c3fac544c0c68229b1d3744efa034fbac.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6072625517845154}",,,,,,,,,,['neutral'],neutral,1 NCT04514796,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2022/08/18/fda-approves-higher-concentration-hadlima-humira-biosimilar/', 'title': 'FDA Approves Higher Concentration of Hadlima, a Humira Biosimilar...', 'source': 'Ankylosing Spondylitis News', 'date': 'Aug 18, 2022', 'snippet': ""The US Food and Drug Administration (FDA) has approved a new, more highly \nconcentrated formulation of Hadlima (adalimumab-bwwd), a biosimilar to \nAbbVie's..."", 'thumbnail': 'https://serpapi.com/searches/672296bad169151c1d6194bd/images/6f5afd5db7b04a40dc30a473862d4db719fc61ee58e8ac664178911a289c52a2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5983152985572815}",,,,,,,,,,['neutral'],neutral,1 NCT00934544,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1110556', 'title': 'JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis', 'source': 'The New England Journal of Medicine', 'date': 'Mar 1, 2012', 'snippet': 'Treatment options for myelofibrosis are limited. We evaluated the efficacy \nand safety of ruxolitinib, a potent and selective Janus kinase...', 'thumbnail': 'https://serpapi.com/searches/672298b3ba13f2d17b1d2e7d/images/d6104c947726d4d553331f4fadda46e3aa31619dd7a01a331d10aba2a788a848.png', 'sentiment': 'neutral', 'sentiment_prob': 0.806252121925354}","{'position': 2, 'link': 'https://www.onclive.com/view/ruxolitinib-improves-spleen-volume-tss-in-myelofibrosis-irrespective-of-baseline-anemia-transfusion-status', 'title': 'Ruxolitinib Improves Spleen Volume, TSS in Myelofibrosis Irrespective of Anemia, Transfusion Status', 'source': 'OncLive', 'date': 'Jun 10, 2023', 'snippet': 'Ruxolitinib was found to improve spleen volume and tumor symptom score in \npatients with myelofibrosis, irrespective of their anemia and...', 'thumbnail': 'https://serpapi.com/searches/672298b3ba13f2d17b1d2e7d/images/d6104c947726d4d5de85cc509d2eda4b9e908509f2ec22d804b60de71fd29743.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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and effective mucosal immunity against H3N2 and H1N1 viruses in mice', 'source': 'ScienceDirect.com', 'date': 'Jan 7, 2024', 'snippet': 'The prokaryotically expressed multiepitope nanovaccine elicits long-lasting \nmucosal immunity, broad humoral immunity, and robust cellular immunity \nwithout any...', 'thumbnail': 'https://serpapi.com/searches/67229905671f3fe9cb22a9ec/images/bc5a4723af82af28cba9ae63c6e6e33d13be4cde76d85228501dfda1042ca830.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6536120176315308}",,,,,,,,,,['neutral'],neutral,1 NCT03558139,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2020/02/14/checkpoint-inhibitor-combination-well-tolerated-effective-in-ovarian-cancer-patients-phase-1b-trial-shows/', 'title': 'OC Patients Show Positive Responses to Magrolimab-Bavencio in Trial', 'source': 'Ovarian Cancer News Today', 'date': 'Feb 14, 2020', 'snippet': 'A mix of the checkpoint inhibitors magrolimab and Bavencio was \nwell-tolerated and showed anti-tumor 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(FDA) has authorized new dosage \nstrengths of Austedo XR (deutetrabenazine) extended-release tablets for \nmanaging chorea.', 'thumbnail': 'https://serpapi.com/searches/67229e6e17a2e2f6d195a3b1/images/cac4f09863eaf1cff6a22e3e1aa637d99cd1a8a16c637fccdf3b76e864fdb4b4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7764703035354614}","{'position': 2, 'link': 'https://huntingtonsdiseasenews.com/news/china-approves-austedo-for-huntingtons-related-chorea/', 'title': 'China Approves Austedo for Huntington’s-related Chorea', 'source': ""Huntington's Disease News"", 'date': 'May 26, 2020', 'snippet': ""Teva Pharmaceuticals' Austedo (deutetrabenazine tablets) has been approved \nby China's National Medical Products Administration (NMPA) for..."", 'thumbnail': 'https://serpapi.com/searches/67229e6e17a2e2f6d195a3b1/images/cac4f09863eaf1cf9f1b764167c1c61f716288f0e53a341f5b621575961ea65c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8606238961219788}",,,,,,,,,"['neutral', 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decision to withdraw the \napproval of Makena (hydroxyprogesterone caproate) and its generic \nequivalents.', 'thumbnail': 'https://serpapi.com/searches/6722a241e1c2761191a8338d/images/f57b8b1425cf9d4ee4538f63d3e6734aa996d57a3ba2701febbbf6a0416a152f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.831075131893158}",,,,,,,,,,['neutral'],neutral,1 NCT03083691,"{'position': 1, 'link': 'https://www.nature.com/articles/s41586-024-07177-7', 'title': 'Evolutionary trajectories of small cell lung cancer under therapy', 'source': 'Nature', 'date': 'Mar 13, 2024', 'snippet': 'We uncover key processes of the genomic evolution of SCLC under therapy, \nidentify the common ancestor as the source of clonal diversity at relapse.', 'thumbnail': 'https://serpapi.com/searches/67229f2c749783416cf3a76e/images/598912582797d70d056fa835ee6dc0035aedd2ef86ae9ac0bd0c5365fab3f869.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9211716055870056}",,,,,,,,,,['neutral'],neutral,1 NCT02853305,"{'position': 1, 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So much is changing. Can you give us an overview..."", 'thumbnail': 'https://serpapi.com/searches/67229fbfe10f0a459b6664c9/images/9a90fa43bd6214d24ffa020f97bc386e0c869cdd105e112886ec129547599862.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9048632383346558}",,,,,,,,,,['neutral'],neutral,1 NCT00634049,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-31788-1', 'title': 'Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies', 'source': 'Nature', 'date': 'Apr 25, 2023', 'snippet': 'Isavuconazole is a triazole with broad-spectrum antifungal activity. 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We sought to evaluate...', 'thumbnail': 'https://serpapi.com/searches/6722a0c6d72128a2208afc3c/images/133418af0d1d7325559f97491a5c38c32a42b80d4e764012bbcbd715bc0e901b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8859652876853943}",,,,,,,,,,['neutral'],neutral,1 NCT03053115,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/news/levothyroxine-plus-liothyronine-improves-biometric-outcomes-not-quality-of-life/', 'title': 'Levothyroxine Plus Liothyronine Improves Biometric Outcomes, Not Quality of Life', 'source': 'Endocrinology Advisor', 'date': 'Jan 11, 2024', 'snippet': 'Levothyroxine plus liothyronine combination therapy was linked to improved \nthyroid levels but unchanged quality of life among hypothyroidism...', 'thumbnail': 'https://serpapi.com/searches/6722a1ede50bc07d7714fc7f/images/8f1ddf3bdc1841dac58d23cf09c93490de4ef1e242a09099f554f9cb2139fdb0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7069607973098755}",,,,,,,,,,['neutral'],neutral,1 NCT02760485,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-0113-2', 'title': 'Advances in targeted therapy for malignant lymphoma', 'source': 'Nature', 'date': 'Mar 6, 2020', 'snippet': 'The incidence of lymphoma has gradually increased over previous decades, \nand it ranks among the ten most prevalent cancers worldwide.', 'thumbnail': 'https://serpapi.com/searches/6722a2eda3657a6c2f22d831/images/73174bc83ee9076d62251d180d3e4f136475830d253040194356133c168e0370.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8373763561248779}",,,,,,,,,,['neutral'],neutral,1 NCT04661514,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02455-9', 'title': 'Psilocybin therapy for females with anorexia nervosa: a phase 1, open-label feasibility study', 'source': 'Nature', 'date': 'Jul 24, 2023', 'snippet': 'Anorexia nervosa (AN) is a deadly illness with no proven treatments to \nreverse core symptoms and no medications approved by the US Food and...', 'thumbnail': 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'https://www.businesswire.com/news/home/20240731398299/en/Otsuka-and-Lundbeck-Present-New-REXULTI%C2%AE-brexpiprazole-Post-Hoc-Efficacy-Data-Analyses-for-Agitation-Associated-with-Dementia-Due-to-Alzheimer%E2%80%99s-Disease-at-Alzheimer%E2%80%99s-Association-International-Conference-AAIC-2024', 'title': 'Otsuka and Lundbeck Present New REXULTI® (brexpiprazole) Post Hoc Efficacy Data Analyses for Agitation Associated with Dementia Due to Alzheimer’s Disease at Alzheimer’s Association International Conference (AAIC) 2024', 'source': 'Business Wire', 'date': 'Jul 31, 2024', 'snippet': ""New analysis from an extension trial confirmed the efficacy of REXULTI in \ntreating patients with agitation associated with dementia due to \nAlzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/6722a3f30d379fd08d192e59/images/9ce94f4dc2e9031cfdb9e61bafc3aba508b512d10efa09573e6bd763c49c6756.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.821667492389679}",,,,,,,,,,['neutral'],neutral,1 NCT02603809,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.14504', 'title': 'Randomized Dose-Response Study of the New Dual Endothelin Receptor Antagonist Aprocitentan in Hypertension', 'source': 'American Heart Association Journals', 'date': 'Feb 17, 2020', 'snippet': 'This study examined the dose-response characteristics of aprocitentan, a \ndual endothelin A/endothelin B receptor antagonist, in patients with \nessential...', 'thumbnail': 'https://serpapi.com/searches/6722a4275ed3cab1a3ea832f/images/2b6dc8a47a1193d75c80ff108e855f60f55a696b80978618e9e1e1e53a4baf4d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9017771482467651}",,,,,,,,,,['neutral'],neutral,1 NCT02399085,"{'position': 1, 'link': 'https://ascopost.com/issues/august-25-2020/tafasitamab-cxix-in-the-treatment-of-diffuse-large-b-cell-lymphoma/', 'title': 'Tafasitamab-cxix in the Treatment of Diffuse Large B-Cell Lymphoma', 'source': 'The ASCO Post', 'date': 'Aug 25, 2020', 'snippet': 'In the Clinic provides overviews of novel oncology agents, addressing \nindications, mechanisms of action, administration recommendations,...', 'thumbnail': 'https://serpapi.com/searches/6722a43ab2ebae61ac670c7b/images/1190d524d7288305eef00c08bd68ae5ac08388d3f5aa8beaa27c431cf23b0efc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9126263856887817}","{'position': 2, 'link': 'https://lymphomanewstoday.com/2020/01/14/morphosys-requests-fda-approval-tafasitamab-relapsed-refractory-dlbcl/', 'title': 'MorphoSys Requests FDA Approval of Tafasitamab for Relapsed or Refractory DLBCL', 'source': 'Lymphoma News Today', 'date': 'Jan 14, 2020', 'snippet': 'MorphoSys is asking the US Food and Drug Administration (FDA) to approve \nits CD19 antibody tafasitamab, in combination with Revlimid (lenalidomide), \nto treat...', 'thumbnail': 'https://serpapi.com/searches/6722a43ab2ebae61ac670c7b/images/1190d524d728830517c3305ba92f304ece9e879ada1e5523a7e99316cf9a0430.jpeg', 'sentiment': 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investigation', 'source': 'The Lancet', 'date': 'Mar 20, 2023', 'snippet': 'Obesity is an epidemic and a public health threat. Medical weight \nmanagement remains one of the options for the treatment of excess weight...', 'thumbnail': 'https://serpapi.com/searches/6722a4a621e77b5006cf94bf/images/e8c0d47d0a065f682b927eb8bd218d951d990f932b52f969d6decd1a1e65645d.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6295787692070007}",,,,,,,,,,['negative'],negative,0 NCT00082641,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223004730', 'title': 'Dendritic cell vaccines in breast cancer: Immune modulation and immunotherapy', 'source': 'ScienceDirect.com', 'date': 'Apr 12, 2023', 'snippet': 'In this review, we summarize the immunomodulatory effects and related \nmechanisms of DC vaccine in breast cancer as well as the progress of \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/6722a722240793cdd0158e22/images/a7ad2746621117917e76a3664aca56eff399da800888d11fca57c7ab22865a24.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'May 9, 2022', 'snippet': 'The emergency use authorizations (EUAs) of two mRNA-based severe acute \nrespiratory syndrome coronavirus (SARS-CoV)-2 vaccines approximately...', 'thumbnail': 'https://serpapi.com/searches/6722a77a2c566da2e23fa3a5/images/f16e0834da269bdd9168c627ce746a3a037ecd6bd1dda4050fb8a1d6a16f557d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921474814414978}","{'position': 2, 'link': 'https://www.nature.com/articles/s41541-023-00656-4', 'title': 'An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection | npj Vaccines', 'source': 'Nature', 'date': 'Apr 20, 2023', 'snippet': 'mRNA-1893 generated comparable neutralizing antibody titers to mRNA-1325 at \n1/20th of the dose and provided complete protection from ZIKV challenge in \nnon-...', 'thumbnail': 'https://serpapi.com/searches/6722a77a2c566da2e23fa3a5/images/f16e0834da269bdd22c08886db0abc341d34df70923553a9db52ef270fc7343f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7196072936058044}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04103450,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/vibegron-effective-in-men-with-overactive-bladder-receiving-bph-treatment/', 'title': 'Vibegron Effective in Men With Overactive Bladder Receiving BPH Treatment', 'source': 'Medical Professionals Reference', 'date': 'Sep 11, 2023', 'snippet': 'A phase 3 study evaluating vibegron in men with OAB symptoms receiving \npharmacological therapy for BPH met its coprimary and all secondary...', 'thumbnail': 'https://serpapi.com/searches/6722a8447ebde58fad24c624/images/48c657537f67816e4005c577cc510c05ab8553e12d239c3605bf2e3f1dc33200.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7995201945304871}",,,,,,,,,,['neutral'],neutral,1 NCT02316197,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-01151-6', 'title': 'A first-in-man phase 1 study of the DNA-dependent protein kinase inhibitor peposertib (formerly M3814) in patients with advanced solid tumours', 'source': 'Nature', 'date': 'Nov 24, 2020', 'snippet': 'This open-label, phase 1 trial (NCT02316197) aimed to determine the \nmaximum-tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of...', 'thumbnail': 'https://serpapi.com/searches/6722a86018787d0b95978bfb/images/79d1d98009d069aab095dc22b982027dab38127df71295e4f483dea8a604337d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9168863892555237}",,,,,,,,,,['neutral'],neutral,1 NCT00346164,"{'position': 1, 'link': 'https://www.onclive.com/view/investigating-risk-based-treatment-strategies-for-pediatric-non-rhabdomyosarcoma-soft-tissue-sarcoma', 'title': 'Investigating Risk-Based Treatment Strategies for Pediatric Non-Rhabdomyosarcoma Soft-Tissue Sarcoma', 'source': 'OncLive', 'date': 'Jul 7, 2024', 'snippet': 'A phase 3 trial (NCT00346164; ARST 0332) is investigating risk-based \ntreatment strategies for patients under the age of 30 with \nnon-rhabdomyosarcoma soft...', 'thumbnail': 'https://serpapi.com/searches/6722a8992da15704c0e272a3/images/5f8daa6526046a3e9a842c77944ec2836027a449d4b060e60c8f1a281f255bef.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9119342565536499}",,,,,,,,,,['neutral'],neutral,1 NCT01313676,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/inhaled-corticosteroids-do-not-increase-risk-for-pneumonia-in-copd/', 'title': 'Inhaled Corticosteroids Do Not Increase Risk for Pneumonia in COPD', 'source': 'Pulmonology Advisor', 'date': 'Oct 20, 2017', 'snippet': 'In contrast to previous study findings, inhaled corticosteroids do not \nappear to increase risk for pneumonia in patients with COPD with...', 'thumbnail': 'https://serpapi.com/searches/6722a8bf48c42962df24cb42/images/1995024893841a3ace77d0a3692172a9b4b6b027febcc294ed964aaaf4ef1867.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7664764523506165}",,,,,,,,,,['neutral'],neutral,1 NCT00000102,"{'position': 1, 'link': 'https://towardsdatascience.com/clinical-trial-outcome-prediction-a4c6d279fd42', 'title': 'Clinical Trial Outcome Prediction', 'source': 'Towards Data Science', 'date': 'Oct 19, 2023', 'snippet': 'I recently came across this article: HINT: Hierarchical interaction network \nfor clinical-trial-outcome predictions from Fu et al.', 'thumbnail': 'https://serpapi.com/searches/6722a8e2740bdb65847033f6/images/268feab5cb3b67e88429fc5dd022f375d6e25dd51a0861d117f21367c3eb6b0e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9227460026741028}",,,,,,,,,,['neutral'],neutral,1 NCT02460198,"{'position': 1, 'link': 'https://ascopubs.org/doi/abs/10.1200/jco.19.02107', 'title': 'Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164 | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Nov 14, 2019', 'snippet': 'KEYNOTE-164 (NCT02460198) evaluated the antitumor activity of pembrolizumab \nin previously treated, metastatic, microsatellite instability–high/mismatch \nrepair–...', 'thumbnail': 'https://serpapi.com/searches/6722a9297a12fdc533090235/images/f83134b9bf937ed054e774bef81b78bab2c87cdaa73265142aadcdea2592ac3a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8730010986328125}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/fda-gives-full-approval-to-pembrolizumab-in-dmmr-msi-h-solid-tumors', 'title': 'FDA Gives Full Approval to Pembrolizumab in dMMR/MSI-H Solid Tumors', 'source': 'Cancer Network', 'date': 'Mar 29, 2023', 'snippet': 'Based on results from the phase 2 KEYNOTE-158, KEYNOTE-164, and KEYNOTE-051 \ntrials, the FDA has given full approval to pembrolizumab for...', 'thumbnail': 'https://serpapi.com/searches/6722a9297a12fdc533090235/images/f83134b9bf937ed0e6b2bdafe501aa54bafbc2bb0138aa46bdda92f5000ca834.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7076309323310852}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01313624,"{'position': 1, 'link': 'https://bronchiectasisnewstoday.com/2020/05/18/cayston-effective-for-some-bronchiectasis-symptoms-but-not-all-study/', 'title': 'Antibiotic Cayston Effective for Some Bronchiectasis Symptoms but Not All, Study Says', 'source': 'Bronchiectasis News Today', 'date': 'May 18, 2020', 'snippet': 'Treatment with the inhaled antibiotic Cayston (aztreonam lysine) reduced \ncough and sputum production, but was not effective against breathlessness \nand wheezing...', 'thumbnail': 'https://serpapi.com/searches/6722a96959f9112ff993c96a/images/ae50f44f68ecc8b08bbe1e5a0415484f6caf32fa1eda962294d05fa3abc83b83.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5014094710350037}",,,,,,,,,,['negative'],negative,0 NCT00748644,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/blocking-b-and-t-cells-interaction-contributes-to-rituxan-efficacy-in-aav-study-says/', 'title': ""Rituxan's Efficacy Linked to It Blocking How B-cells Interact with Certain T-cells, Study Says"", 'source': 'ANCA Vasculitis News', 'date': 'Nov 20, 2018', 'snippet': 'Blocking the interaction between immune B-cells and CD8-positive T-cells \nmay be what makes Rituxan (rituximab) an effective treatment for \nANCA-associated...', 'thumbnail': 'https://serpapi.com/searches/6722aa05f9f9043541f13966/images/1c31dbab4ef2e646dd0bbdbdfa07e322ca7df101422149d9ee25cb1b0f761eb0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8923890590667725}",,,,,,,,,,['neutral'],neutral,1 NCT04380142,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/fda-issues-second-abbv-951-rejection-parkinsons-motor-fluctuations/', 'title': 'FDA issues second rejection of ABBV-951 for motor fluctuations', 'source': ""Parkinson's News Today"", 'date': 'Jun 26, 2024', 'snippet': ""The U.S. Food and Drug Administration (FDA) has rejected for the second \ntime AbbVie's application of ABBV-951 (foscarbidopa/foslevodopa) for..."", 'thumbnail': 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therapy approved as Vyalev for advanced Parkinson’s', 'source': ""Parkinson's News Today"", 'date': '2 weeks ago', 'snippet': 'The U.S. Food and Drug Administration (FDA) has approved foslevodopa and \nfoscarbidopa, a levodopa therapy given as a 24-hour under-the-skin...', 'thumbnail': 'https://serpapi.com/searches/6722ab8a2e33c8a63deb95c6/images/51b31c620f152adc480037febd8e70357307d767ec713981091e08a9ec6b57b5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.694657564163208}","{'position': 4, 'link': 'https://parkinsonsnewstoday.com/news/abbvie-produodopa-advanced-parkinsons-eu/', 'title': 'AbbVie launches Produodopa for advanced Parkinson’s in EU', 'source': ""Parkinson's News Today"", 'date': 'Jan 12, 2024', 'snippet': ""AbbVie has launched Produodopa, its continuous carbidopa/levodopa infusion \ntherapy, for advanced Parkinson's patients in the European Union."", 'thumbnail': 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arrives in Canada"", 'source': ""Parkinson's News Today"", 'date': 'Feb 12, 2024', 'snippet': 'The continuous, infusion pump therapy is for advanced disease and severe \nfluctuations no longer controlled by oral levodopa/carbidopa.', 'thumbnail': 'https://serpapi.com/searches/6722ab8a2e33c8a63deb95c6/images/51b31c620f152adc817b673a7c906ed958121aea15cf2291bb3647f091d8d461.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8271430730819702}","{'position': 7, 'link': 'https://parkinsonsnewstoday.com/news/abbv-951-now-available-low-no-cost-england-certain-patients/', 'title': 'ABBV-951 now available at low, no cost in England to certain patients', 'source': ""Parkinson's News Today"", 'date': 'Oct 30, 2023', 'snippet': ""ABBV-951 (foslevodopa/foscarbidopa) — Abbvie's continuous infusion \nformulation of levodopa/carbidopa that's administered under the skin..."", 'thumbnail': 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The anti-obesity drugs market \nsize was valued at $1,605.36 million in 2022 and is estimated to reach \n$4,439.34...', 'thumbnail': 'https://serpapi.com/searches/6722b023a86921c14170d7b7/images/7b0e9dba16151d1751f9e896c58d85269e822e0d858a3eae4ff5f6f91269ffe4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.879167914390564}",,,,,"['neutral', 'negative', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00546793,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1038/icb.2017.6', 'title': 'Immunology & Cell Biology | ASI Journal', 'source': 'Wiley Online Library', 'date': 'Feb 21, 2017', 'snippet': 'The April 2017 issue of Immunology & Cell Biology contains a Special \nFeature on Cancer Immunotherapy. This series of reviews highlights some...', 'thumbnail': 'https://serpapi.com/searches/6722b0cc90adce4a729e5781/images/cf59fe0eafa2b0e0074ddd6ccc8ad5adab6077ae1a09fbe2336385b7102ee732.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.942265510559082}",,,,,,,,,,['neutral'],neutral,1 NCT01516879,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1316222', 'title': 'A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia', 'source': 'The New England Journal of Medicine', 'date': 'Mar 29, 2014', 'snippet': 'Evolocumab, a monoclonal antibody that inhibits proprotein convertase \nsubtilisin/kexin type 9 (PCSK9), significantly reduced low-density...', 'thumbnail': 'https://serpapi.com/searches/6722b19798876d773369d1b9/images/467ca517731e1f034910e96be04c7fd8b6e99e71ed2ebaf514194296fc84917b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8380778431892395}",,,,,,,,,,['neutral'],neutral,1 NCT01606241,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-020-18962-z', 'title': 'Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients', 'source': 'Nature', 'date': 'Oct 14, 2020', 'snippet': 'In ovarian cancer (OC), IL-17-producing T cells (Th17s) predict improved \nsurvival, whereas regulatory T cells predict poorer survival.', 'thumbnail': 'https://serpapi.com/searches/6722b1dbd0c983e63245d0c9/images/8cf510c9bd4c68b4847c1f7a2d2bb1949096579a392ec8e78386ba22f72bfb9c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6748889684677124}",,,,,,,,,,['neutral'],neutral,1 NCT03354429,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1916870', 'title': 'Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA', 'source': 'The New England Journal of Medicine', 'date': 'Jul 15, 2020', 'snippet': 'Trials have evaluated the use of clopidogrel and aspirin to prevent stroke \nafter an ischemic stroke or transient ischemic attack (TIA).', 'thumbnail': 'https://serpapi.com/searches/6722b1f05ddfba0914de1d52/images/a2551d9cd58d001fb7a8284b0b7df43f3f4b2b84ddbbadd87e65c57e223aef42.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8524799942970276}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.032239', 'title': 'Ticagrelor Added to Aspirin in Acute Nonsevere Ischemic Stroke or Transient Ischemic Attack of Atherosclerotic Origin', 'source': 'American Heart Association Journals', 'date': 'Nov 16, 2020', 'snippet': 'Background and Purpose:Among patients with a transient ischemic attack or \nminor ischemic strokes, those with ipsilateral atherosclerotic...', 'thumbnail': 'https://serpapi.com/searches/6722b1f05ddfba0914de1d52/images/a2551d9cd58d001fdcaa93cedd2abf4e4086871055172361e34cc050c636a898.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8694614171981812}","{'position': 3, 'link': 'https://www.neurologylive.com/view/ticagrelor-fda-approved-for-recurrent-stroke-prevention', 'title': 'Ticagrelor Approved for Recurrent Stroke Prevention', 'source': 'Neurology live', 'date': 'Nov 6, 2020', 'snippet': 'The decision was based on findings from the phase 3 THALES trial, which \nshowed aspirin plus ticagrelor significantly reduced stroke and...', 'thumbnail': 'https://serpapi.com/searches/6722b1f05ddfba0914de1d52/images/a2551d9cd58d001f032895661f0c453047dccdead4b3fb4656e1181211548cd8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5632188320159912}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02241135,"{'position': 1, 'link': 'https://www.nature.com/articles/s41587-022-01294-2', 'title': 'The clinical progress of mRNA vaccines and immunotherapies', 'source': 'Nature', 'date': 'May 9, 2022', 'snippet': 'The emergency use authorizations (EUAs) of two mRNA-based severe acute \nrespiratory syndrome coronavirus (SARS-CoV)-2 vaccines approximately...', 'thumbnail': 'https://serpapi.com/searches/6722b22135853984af1106d0/images/2eed3adc99587474016241cbc62598155e3a36d1231338dfa4e5c8795554b383.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921474814414978}",,,,,,,,,,['neutral'],neutral,1 NCT03912233,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/vertex-phase-3-trials-vx121-vx561-tezacaftor-triple-combination-cf-therapy/', 'title': 'Vertex Planning Phase 3 Trials in New Triple Combo Therapy for CF', 'source': 'Cystic Fibrosis News Today', 'date': 'Jul 30, 2021', 'snippet': 'Vertex Pharmaceuticals is initiating two Phase 3 clinical trials into the \nsafety and efficacy of a potentially new, next-generation triple...', 'thumbnail': 'https://serpapi.com/searches/6722b258c97e356b10d6ae77/images/3d2868697807fa071838d08ba18512336ce838f7183f99445b4f6c5e99a70cdf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8972020149230957}",,,,,,,,,,['neutral'],neutral,1 NCT04969276,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/home/general-medicine/quadrivalent-influenza-vaccine-qiv-hd-mrna-covid-19-vaccine-safe-phase-2-clinical-trial/', 'title': 'Coadministration of QIV-HD Influenza Vaccine, mRNA-1273 COVID-19 Vaccine Is Safe', 'source': 'Cancer Therapy Advisor', 'date': 'Mar 16, 2022', 'snippet': 'Phase 2 results indicate no safety concerns or immune interference for \nadults who receive concomitant QIV-HD and mRNA-1273 vaccination.', 'thumbnail': 'https://serpapi.com/searches/6722b4b2efad219305049743/images/e9da91275c21551fe82f8feb55e1621158a679e2dc5bbbe59d952018f5816be3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6734781861305237}",,,,,,,,,,['neutral'],neutral,1 NCT06129409,"{'position': 1, 'link': 'https://www.nature.com/articles/s12276-024-01261-8', 'title': 'NLRP3 inflammasome: a key player in the pathogenesis of life-style disorders', 'source': 'Nature', 'date': 'Jul 1, 2024', 'snippet': 'Proinflammatory cytokines and chemokines play a crucial role in regulating \nthe inflammatory response, which is essential for the proper...', 'thumbnail': 'https://serpapi.com/searches/6722b5db4a4a1d0f4b82749f/images/236af27967fe85c26ac067afed759032496a20931ca30489bdaf38c2ce2f76e5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8756292462348938}",,,,,,,,,,['neutral'],neutral,1 NCT00887198,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1209096', 'title': 'Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy', 'source': 'The New England Journal of Medicine', 'date': 'Dec 10, 2012', 'snippet': 'The study was unblinded after a planned interim analysis that was performed \nafter 43% of the expected deaths had occurred.', 'thumbnail': 'https://serpapi.com/searches/6722b66193bb57b0a3dfcb56/images/e1c2105576be5a924f8490f55d02f26961c556090be8f80bc204cb76a75e4638.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.514735758304596}","{'position': 2, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)71205-7/fulltext', 'title': 'Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 stud', 'source': 'The Lancet', 'date': 'Jan 15, 2015', 'snippet': 'Abiraterone acetate plus prednisone versus placebo plus prednisone in \nchemotherapy-naive men with metastatic castration-resistant prostate cancer', 'thumbnail': 'https://serpapi.com/searches/6722b66193bb57b0a3dfcb56/images/e1c2105576be5a9212f52dcf35347696bbefe65134ae0688f57e6f9be86403a0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8303014636039734}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01664923,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.2015.64.9285', 'title': 'Enzalutamide Versus Bicalutamide in Castration-Resistant Prostate Cancer: The STRIVE Trial', 'source': 'ASCO Publications', 'date': 'Mar 22, 2019', 'snippet': 'PurposeEnzalutamide, a potent oral androgen receptor inhibitor, improves \nsurvival in men with metastatic castration-resistant prostate cancer (CRPC) \nbefore...', 'thumbnail': 'https://serpapi.com/searches/6722b680e281ee0144ea51dc/images/c3769bda3def856f56987ca58098a6be1707a0a72f74181e0a056b08ab6fdf8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6053585410118103}",,,,,,,,,,['neutral'],neutral,1 NCT04629443,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-024-06810-7', 'title': 'Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia | Cell Death & Disease', 'source': 'Nature', 'date': 'Jun 12, 2024', 'snippet': 'We review the emerging mechanisms of intrinsic and acquired venetoclax \nresistance in AML and highlight recent efforts to identify novel strategies \nto overcome...', 'thumbnail': 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In animal models, ABBV-467 led to cancer cell \ndeath...', 'thumbnail': 'https://serpapi.com/searches/6722b7bbc05eb5bbb96986ea/images/c879124a76ef66f676cc5534aa8299b9b6338fea3a4e0887c9c5f9faa792d53a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.680879533290863}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02343458,"{'position': 1, 'link': 'https://copdnewstoday.com/news/bevespi-aerosphere-demonstrates-statistically-significant-improvement-in-lung-function-in-patients-with-copd/', 'title': 'Bevespi Aerosphere Progressing Toward OK for COPD in Europe, Asia', 'source': 'COPD News Today', 'date': 'Oct 5, 2017', 'snippet': ""Learn more about positive results on AstraZeneca's Bevespi Aerosphere \nPINNACLE 4 clinical trial in patients with moderate to very severe..."", 'thumbnail': 'https://serpapi.com/searches/6722b7f2db3ac9838cb84a26/images/e2dbc907124692eb4a314a32f3c267de106cb0d35028073ee9095fe0edca8f68.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6521616578102112}","{'position': 2, 'link': 'https://copdnewstoday.com/news/aeristo-copd-trial-shows-bevespi-aerosphere-similar-to-anoro-elipta/', 'title': 'Bevespi Aerosphere Shows Similar Effectiveness as Anoro Elipta for...', 'source': 'COPD News Today', 'date': 'Aug 24, 2018', 'snippet': ""Read the latest AERISTO clinical trial data on AstraZeneca's Bevespi \nAerosphere for the treatment of COPD as compared to GSK's Anoro Elipta."", 'thumbnail': 'https://serpapi.com/searches/6722b7f2db3ac9838cb84a26/images/e2dbc907124692eb681c1d46200a6887cba0594d7c5397ad9168e78f065daf43.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.858304500579834}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04177108,"{'position': 1, 'link': 'https://www.targetedonc.com/view/investigators-tailor-tnbc-therapy-using-genomic-alterations', 'title': 'Investigators Tailor TNBC Therapy Using Genomic Alterations', 'source': 'Targeted Oncology', 'date': 'Oct 21, 2020', 'snippet': 'In a presentation at the 2020 Lynn Sage Breast Cancer Symposium, Virginia \nG. Kaklamani, MD, DSc, reviewed the current genomic tools in the...', 'thumbnail': 'https://serpapi.com/searches/6722b7fc93bb57b04c3db2bc/images/d5b46cae95fb40d45cfb8d270bd260a53ef21389165a5578fe49c15ead262082.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9546643495559692}",,,,,,,,,,['neutral'],neutral,1 NCT03987919,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2107519', 'title': 'Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Jun 25, 2021', 'snippet': 'Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and \nglucagon-like peptide-1 (GLP-1) receptor agonist that is under development \nfor the...', 'thumbnail': 'https://serpapi.com/searches/6722b80b76079d5720a0b842/images/9bdfdf32bd826a8d01f37054c70480273b941cf93d0216217ded97f58f3647f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9040133357048035}","{'position': 2, 'link': 'https://www.renalandurologynews.com/news/tirzepatide-vs-semaglutide-lower-metabolic-syndrome-prevalence/', 'title': 'Tirzepatide vs Semaglutide Linked to Lower Metabolic Syndrome Prevalence', 'source': 'Renal and Urology News', 'date': 'Apr 12, 2024', 'snippet': 'Use of tirzepatide, compared with placebo, semaglutide, and insulin \ndegludec and glargine, is associated with a lower prevalence of metabolic \nsyndrome among...', 'thumbnail': 'https://serpapi.com/searches/6722b80b76079d5720a0b842/images/9bdfdf32bd826a8d91272658ea1fd97d3f5171d743e9433e58afc1582136d8ba.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8086218237876892}","{'position': 3, 'link': 'https://investor.lilly.com/news-releases/news-release-details/lillys-surpass-2-results-published-new-england-journal-medicine', 'title': ""Lilly's SURPASS-2 results published in The New England Journal of Medicine show tirzepatide achieved superior A1C and body weight reductions compared to injectable semaglutide in adults with type 2 diabetes"", 'source': 'Eli Lilly and Company', 'date': 'Jun 25, 2021', 'snippet': ""Lilly's SURPASS-2 results published in The New England Journal of Medicine \nshow tirzepatide achieved superior A1C and body weight reductions..."", 'thumbnail': 'https://serpapi.com/searches/6722b80b76079d5720a0b842/images/9bdfdf32bd826a8d8ea2cf3d0d03729cb11585e2f2f6ab7bffab7e166eb2a5a3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7059458494186401}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03545191,"{'position': 1, 'link': 'https://www.empr.com/home/news/quviviq-approved-for-the-treatment-of-insomnia/', 'title': 'Quviviq Approved for the Treatment of Insomnia', 'source': 'Medical Professionals Reference', 'date': 'Jan 10, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Quviviq™ (daridorexant) \nfor the treatment of adults with insomnia characterized by...', 'thumbnail': 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'https://www.onclive.com/view/pembrolizumab-plus-b-cell-receptor-inhibitors-generates-response-in-richter-transformation-of-cll-sll', 'title': 'Pembrolizumab Plus B-Cell Receptor Inhibitors Generates Responses in Richter Transformation of CLL/SLL', 'source': 'OncLive', 'date': 'Jul 22, 2024', 'snippet': 'The addition of a B-cell receptor (BCR) inhibitor to pembrolizumab \n(Keytruda) led to responses in patients with Richter transformation of \nchronic lymphocytic...', 'thumbnail': 'https://serpapi.com/searches/6722b9dde10f0a45ebd65498/images/c90e695b213cc8223465226115c708f482414e76b7399bd9c2ea8ef619225176.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8919400572776794}","{'position': 2, 'link': 'https://www.nature.com/articles/s41408-021-00477-5', 'title': 'Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome', 'source': 'Nature', 'date': 'May 10, 2021', 'snippet': 'Richter syndrome (RS) refers to transformation of chronic lymphocytic \nleukemia (CLL) to an aggressive lymphoma, most commonly diffuse large \nB-cell lymphoma.', 'thumbnail': 'https://serpapi.com/searches/6722b9dde10f0a45ebd65498/images/c90e695b213cc822c9542aaca1c20f388893a04069e52649fefc1ecb1085601f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7535958290100098}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04932941,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00229-6/fulltext', 'title': 'Efficacy and safety of MP1032 plus standard-of-care compared to standard-of-care in hospitalised patients with COVID-19: a multicentre, randomised double-blind, placebo-controlled phase 2a trial', 'source': 'The Lancet', 'date': 'Dec 6, 2023', 'snippet': 'We assessed here the efficacy and safety of MP1032, a host-directed \nanti-viral/anti-inflammatory drug in hospitalised patients with moderate to \nsevere COVID-19.', 'thumbnail': 'https://serpapi.com/searches/6722b9f820e6eb462887bfda/images/51d6261f7bcf95527963d1b19b6323813e775ad95bbc7fbfadd401c2f2fe3898.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8371482491493225}",,,,,,,,,,['neutral'],neutral,1 NCT02220725,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1510991', 'title': 'Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity', 'source': 'The New England Journal of Medicine', 'date': 'Nov 11, 2015', 'snippet': 'Andexanet reversed the anticoagulant activity of apixaban and rivaroxaban \nin older healthy participants within minutes after administration and for \nthe...', 'thumbnail': 'https://serpapi.com/searches/6722bae4717bff91dacafe61/images/ddfb9853a4466a1ce4f8efc4dc5d316eb38aa937e6268b4de4535b3f0bd75cad.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9071860909461975}",,,,,,,,,,['neutral'],neutral,1 NCT03308565,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-46259-y', 'title': 'Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial', 'source': 'Nature', 'date': 'Apr 1, 2024', 'snippet': 'Intrathecal delivery of autologous culture-expanded adipose tissue-derived \nmesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal \ncord...', 'thumbnail': 'https://serpapi.com/searches/6722bc04d771bd6b2e5e1b06/images/2c46d57890091caeb1111f7721918021dc617ff142120345820d3f128e2cdbb4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8826764822006226}",,,,,,,,,,['neutral'],neutral,1 NCT02578901,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/news/thrombocytopenia-tranexamic-acid-prophylaxis-improve-bleeding-risk-treatment/', 'title': 'Tranexamic Acid Prophylaxis Does Not Improve Bleeding Risk for Thrombocytopenia in Hematologic Malignancies', 'source': 'Hematology Advisor', 'date': 'Oct 4, 2022', 'snippet': 'Recent clinical trial results suggest that in patients receiving certain \ntreatments for hematologic malignancy who are at risk of...', 'thumbnail': 'https://serpapi.com/searches/6722bcbf0664c9fe85c66a52/images/0428b1147910dec4b744c994294d6fdb8102c83556c01a49fed8fca37860b584.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.695556104183197}",,,,,,,,,,['negative'],negative,0 NCT03030105,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/fda-grants-bpn14770-orphan-drug-status-fragile-x-syndrome/', 'title': 'Potential Fragile X Therapy BPN14770 Receives FDA Orphan Drug Status', 'source': 'Fragile X News Today', 'date': 'Apr 12, 2018', 'snippet': 'Investigational therapy BPN14770 has been granted orphan drug status by the \nU.S. Food and Drug Administration for the treatment of fragile X...', 'thumbnail': 'https://serpapi.com/searches/6722c1e2e1c27611dea9b2eb/images/3ca4f7a4078183f7e36032dff80b113c93a44664b2b890a9a51b1a1edca3faaa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8758559226989746}",,,,,,,,,,['neutral'],neutral,1 NCT02106832,"{'position': 1, 'link': 'https://bronchiectasisnewstoday.com/2017/07/18/ciprofloxacin-dpi-bayer-treating-non-cystic-fibrosis-bronchiectasis/', 'title': 'Bayer’s Ciprofloxacin DPI Shows Promise in Treating Non-cystic Fibrosis Bronchiectasis', 'source': 'Bronchiectasis News Today', 'date': 'Jul 18, 2017', 'snippet': 'Bayer is conducting two Phase 3 clinical trials evaluating ciprofloxacin \nDry Powder for Inhalation (ciprofloxacin DPI) as a treatment for...', 'thumbnail': 'https://serpapi.com/searches/6722bd8958e433496eb8fec9/images/a90c5bef79b49dea8953aa8e7c4a5151de1df1ff07edafcd6e0b769e32a50031.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7611814737319946}","{'position': 2, 'link': 'https://bronchiectasisnewstoday.com/2017/11/17/fda-panel-opposed-ciprofloxacin-dry-powder-for-inhalation-cipro-dpi-to-treat-non-cf-bronchiectasis/', 'title': 'FDA Panel Opposes Use of Cipro DPI to Treat Non-CF Bronchiectasis', 'source': 'Bronchiectasis News Today', 'date': 'Nov 17, 2017', 'snippet': 'A US Food and Drug Administration (FDA) advisory panel voted not to \nrecommend ciprofloxacin dry powder for inhalation (Cipro DPI), being \ndeveloped by Bayer, to...', 'thumbnail': 'https://serpapi.com/searches/6722bd8958e433496eb8fec9/images/a90c5bef79b49dea05bed0af2adda4f27f207e7cd21f1e1cee176394405c6c52.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5384337902069092}","{'position': 3, 'link': 'https://bronchiectasisnewstoday.com/2018/01/04/top-10-bronchiectasis-stories-2017/', 'title': 'Top 10 Bronchiectasis Stories of 2017', 'source': 'Bronchiectasis News Today', 'date': 'Jan 4, 2018', 'snippet': ""Here are Bronchiectasis News Today's Top 10 most-read stories of 2017 with \nsummaries of why they were interesting to bronchiectasis patients..."", 'thumbnail': 'https://serpapi.com/searches/6722bd8958e433496eb8fec9/images/a90c5bef79b49dea365e2ec560f1de5c2458c87d5e494a128336f2f1f468a09d.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5398268699645996}",,,,,,,,"['neutral', 'neutral', 'positive']",neutral,1 NCT04688164,"{'position': 1, 'link': 'https://www.psychiatrist.com/pcc/subanalysis-of-subjective-cognitive-measures-from-a-phase-2-double-blind-randomized-trial-of-rel-1017-in-patients-with-major-depressive-disorder/', 'title': 'Subanalysis of Subjective Cognitive Measures From a Phase 2, Double-Blind, Randomized Trial of REL-1017 in Patients With Major Depressive Disorder', 'source': 'Psychiatrist.com', 'date': 'Feb 14, 2023', 'snippet': 'REL-1017 improved subjective measures of cognitive impairment, in addition \nto improving total MADRS and SDQ scores.', 'thumbnail': 'https://serpapi.com/searches/6722bdc6861b9dc3860ce5b6/images/e845fd17280e9149d68f9f7251cc6c3eb9cedb301e31829adf32ce433ecb6d18.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8551734685897827}",,,,,,,,,,['neutral'],neutral,1 NCT03282149,"{'position': 1, 'link': 'https://finance.yahoo.com/news/xalud-therapeutics-presents-clinical-data-120000385.html', 'title': 'Xalud Therapeutics Presents 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(TSE: 4503, President and CEO: Kenji \nYasukawa, Ph.D., ""Astellas"") and the Blood and Marrow Transplant...', 'thumbnail': 'https://serpapi.com/searches/6722c3c2667ec536558eb418/images/46ee387ee27982200246621738305a56255cd0867948e808120df236551f50e6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9033066630363464}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01636141,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332221002274', 'title': 'Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease', 'source': 'ScienceDirect.com', 'date': 'Mar 3, 2021', 'snippet': 'The incidence and prevalence of inflammatory bowel disease (IBD) are \nincreasing worldwide. 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(NYSE: PFE) today announced positive top-line immunogenicity \nand safety data from the ongoing pivotal Phase 3 clinical trial...', 'thumbnail': 'https://serpapi.com/searches/6722c572272a878897ddf53d/images/159337a95da7d9857b445896d789f5f8ffbe75d5963907974b178a6019849654.png', 'sentiment': 'positive', 'sentiment_prob': 0.6759746074676514}","{'position': 4, 'link': 'https://www.precisionvaccinations.com/2024/04/09/rsv-vaccine-people-18-59-years-posts-positive-phase-3-results', 'title': 'RSV Vaccine for People 18 to 59 Years Posts Positive Phase 3 Results', 'source': 'Precision Vaccinations News', 'date': 'Apr 9, 2024', 'snippet': 'Pfizer Inc. today reported encouraging top-line data regarding the safety \nand immunogenicity of its ABRYSVO® vaccine from an ongoing Phase 3...', 'thumbnail': 'https://serpapi.com/searches/6722c572272a878897ddf53d/images/159337a95da7d985b4e8127ad6f0796a8438b03c15b97cc109e4dded8cf81730.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6904248595237732}","{'position': 5, 'link': 'https://www.drugtopics.com/view/fda-approves-abrysvo-for-adults-18-59-at-increased-risk-for-rsv', 'title': 'FDA Approves Abrysvo for Adults 18-59 at Increased Risk for RSV', 'source': 'Drug Topics', 'date': '1 week ago', 'snippet': ""Pfizer's respiratory syncytial virus (RSV) vaccine Abrysvo has been \napproved by the FDA for the prevention RSV-associated of lower..."", 'thumbnail': 'https://serpapi.com/searches/6722c572272a878897ddf53d/images/159337a95da7d985d31d568ffd4ab111c3295bdfa763d0c0ba165741ebd39a04.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.857796311378479}","{'position': 6, 'link': 'https://www.businesswire.com/news/home/20241018199265/en/U.S.-FDA-Approves-Pfizer%E2%80%99s-RSV-Vaccine-ABRYSVO%C2%AE-for-Adults-Aged-18-to-59-at-Increased-Risk-for-Disease', 'title': 'U.S. FDA Approves Pfizer’s RSV Vaccine ABRYSVO® for Adults Aged 18 to 59 at Increased Risk for Disease', 'source': 'Business Wire', 'date': '1 week ago', 'snippet': 'Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug \nAdministration (FDA) has approved ABRYSVO® (Respiratory Syncytial Virus...', 'thumbnail': 'https://serpapi.com/searches/6722c572272a878897ddf53d/images/159337a95da7d985714151323775cd9f0b4d635dab6ef8ba7076ab782cd415f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8342057466506958}",,,,,"['neutral', 'positive', 'positive', 'positive', 'neutral', 'neutral']",neutral,1 NCT00014911,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa061267', 'title': 'International Trial of the Edmonton Protocol for Islet Transplantation', 'source': 'The New England Journal of Medicine', 'date': 'Jan 29, 2017', 'snippet': 'Islet transplantation offers the potential to improve glycemic control in a \nsubgroup of patients with type 1 diabetes mellitus who are disabled by...', 'thumbnail': 'https://serpapi.com/searches/6722c57b163bdffdff21f419/images/04862eb7d370d13f1684e754ea958478ab07aa8c2b7924337f264f741a5bd980.jpeg', 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extended-release injectable suspension for the treatment...', 'thumbnail': 'https://serpapi.com/searches/6722c7f2c1c8dda202219ac2/images/c0a5e6a601a842573febf140fda201cb9df246af8bc0f8a6fd81082d6c500295.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7432510852813721}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04311034,"{'position': 1, 'link': 'https://www.oncozine.com/remegen-initiates-clinical-trial-for-distamab-vedotin-a-novel-anti-her2-antibody-drug-conjugate/', 'title': 'RemeGen Initiates Clinical Trial for Distamab vedotin, a Novel anti-HER2 Antibody-drug Conjugate', 'source': ""Onco'Zine"", 'date': 'May 1, 2020', 'snippet': 'Earlier this week, the U.S. Food and Drug Administration (FDA) has cleared \nan Investigational New Drug (IND) application allowing...', 'thumbnail': 'https://serpapi.com/searches/6722c83a6a5dd373ed507c3f/images/05334d9d729d9f9edea2816f0f2f10a18e39c11500b72b4f35d9d210c43f13f4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Professionals Reference', 'date': 'Mar 24, 2023', 'snippet': 'Treatment with risankizumab resulted in clinical remission and an \nimprovement in symptoms, according to findings from the phase 3 INSPIRE \ninduction study.', 'thumbnail': 'https://serpapi.com/searches/6722c72f5ed3cab1ee1bf9d4/images/62a212b9e1a3112d9af153a70ca5777488893b3d2219c0fc314e36d98063e12c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6772766709327698}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/clinical-remission-observed-with-risankizumab-in-ulcerative-colitis-maintenance-study/', 'title': 'Clinical Remission Observed With Risankizumab in Ulcerative Colitis Maintenance Study', 'source': 'Medical Professionals Reference', 'date': 'Jun 15, 2023', 'snippet': 'Treatment with risankizumab led to a significant proportion of adults with \nmoderately to severely active ulcerative colitis achieving clinical \nremission.', 'thumbnail': 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'title': 'A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias', 'source': 'The New England Journal of Medicine', 'date': 'Apr 24, 2018', 'snippet': 'We conducted a phase 2 trial of ponatinib in patients with chronic myeloid \nleukemia (CML) or Philadelphia chromosome–positive acute lymphoblastic \nleukemia (Ph-...', 'thumbnail': 'https://serpapi.com/searches/6722c8e89062f8d53b311a8c/images/528e99fd57836572a07d85a969d8d708cb3aad4627e4987d1086474cc67dd97d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9004957675933838}",,,,,,,,,,['neutral'],neutral,1 NCT02007512,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-023-00544-z', 'title': 'Phase II trial of fulvestrant plus enzalutamide in ER+/HER2− advanced breast cancer | npj Breast Cancer', 'source': 'Nature', 'date': 'May 20, 2023', 'snippet': 'This clinical trial combined fulvestrant with the anti-androgen \nenzalutamide in women with metastatic ER+/HER2− breast cancer (BC).', 'thumbnail': 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'title': 'Semaglutide Improves Prediabetic Glycemic Control', 'source': 'Endocrinology Advisor', 'date': 'Oct 20, 2023', 'snippet': 'Once-daily oral semaglutide 50 mg improved glycemic control among \nindividuals with prediabetes, according to study findings presented at \nObesityWeek® 2023.', 'thumbnail': 'https://serpapi.com/searches/6722c9ec6f9f633c74d9ed5a/images/5b9ebae72e606c95520d1a8792a7b9093b2fc5928517a5dbd574f97612d21107.png', 'sentiment': 'positive', 'sentiment_prob': 0.557879626750946}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04722484,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222002839', 'title': 'Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)', 'source': 'ScienceDirect.com', 'date': 'Apr 2, 2022', 'snippet': 'Vericiguat was first drug approved for the treatment of symptomatic \npatients with chronic HF with reduced ejection fraction (HFrEF) to reduce \nthe occurrence of...', 'thumbnail': 'https://serpapi.com/searches/6722ca40a775f2f8ec0e22b0/images/451fd558a9b11c3967b3d0d6a8ad72973425fd55c8bc4b92190dc23c7b7b964c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6862191557884216}",,,,,,,,,,['neutral'],neutral,1 NCT03132467,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1256360/full', 'title': 'Recent research and clinical progress of CTLA-4-based immunotherapy for breast cancer', 'source': 'Frontiers', 'date': 'Oct 4, 2023', 'snippet': 'Breast cancer is characterized by a high incidence rate and its treatment \nchallenges, particularly in certain subtypes. Consequently, there is an \nurgent...', 'thumbnail': 'https://serpapi.com/searches/6722ca49ecf150c72970d49b/images/1576bcc26f7b1b15e3a7adf2985068255fc592bf158d034f16dbfeaabc30da9c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8037545680999756}",,,,,,,,,,['neutral'],neutral,1 NCT04724837,"{'position': 1, 'link': 'https://www.renalandurologynews.com/reports/zibotentan-dapagliflozin-combo-further-reduces-albuminuria-in-ckd/', 'title': 'Zibotentan, Dapagliflozin Combo Further Reduces Albuminuria in CKD', 'source': 'Renal and Urology News', 'date': 'Nov 8, 2023', 'snippet': 'ZENITH-CKD is the first randomized trial comparing combined SGLT2 and \nendothelin A inhibition in patients with chronic kidney disease.', 'thumbnail': 'https://serpapi.com/searches/6722ca9d20e6eb462887d44b/images/5a715863f6eebbf4edf1ceb06ab1a8b807decab8c46205bab9e8517166f0e3ec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8572437167167664}",,,,,,,,,,['neutral'],neutral,1 NCT01045421,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Kinase-substrate-enrichment-analysis-a-Predicted-upstream-kinases-enriched-across-five_fig5_339042892', 'title': 'Figure 5. Kinase-substrate enrichment analysis. (a) Predicted upstream...', 'source': 'ResearchGate', 'date': 'Feb 6, 2020', 'snippet': 'Download scientific diagram | Kinase-substrate enrichment analysis. (a) \nPredicted upstream kinases enriched across five cancer types.', 'thumbnail': 'https://serpapi.com/searches/6722cbbd5bb6a2400c71c882/images/3c13098865e1b4281a7d54bb465693f43245554167316505c32ec753c240dab1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9439812302589417}",,,,,,,,,,['neutral'],neutral,1 NCT01207388,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/fda-gives-full-approval-to-blinatumomab-in-mrd-positive-b-cell-all', 'title': 'FDA Gives Full Approval to Blinatumomab in MRD-Positive B-Cell ALL', 'source': 'Cancer Network', 'date': 'Jun 21, 2023', 'snippet': 'Blinatumomab has been granted full approval by the FDA for patients with \nB-cell acute lymphoblastic leukemia and minimal residual disease of...', 'thumbnail': 'https://serpapi.com/searches/6722cbccd78a985a6b5acf36/images/7c95c2ac1490abfba5796159bbb1058d5689c7948ac8cdc4ffb9825d7fda5dd5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5017969608306885}",,,,,,,,,,['neutral'],neutral,1 NCT03446001,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/alzheimers-tau-targeting-therapy-slows-cognition-functional-drops-trial/', 'title': 'Tau-targeting Treatment Slows Cognitive, Functional Declines: Trial', 'source': ""Alzheimer's News Today"", 'date': 'Jun 6, 2022', 'snippet': ""Alzheimer's patients given the tau-targeting therapy HMTM in the clinical \ntrial LUCIDITY showed substantially slower declines than expected."", 'thumbnail': 'https://serpapi.com/searches/6722cc1ff6aa53bdf3522017/images/0fbccb5422e183ed9cf4f071765b1b5e0216f119122b021b650b859f69abca5d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5801092386245728}",,,,,,,,,,['neutral'],neutral,1 NCT03433183,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-021-00145-8', 'title': 'Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor', 'source': 'Nature', 'date': 'Feb 12, 2021', 'snippet': 'The prognosis of recurrent malignant peripheral nerve sheath tumors (MPNST) \nis dismal, with surgical resection being the only definitive...', 'thumbnail': 'https://serpapi.com/searches/6722cc6821b01b712dab21cf/images/f986b08782acb252d605ecde211ffa4890ca9a2183eb7211c6c0b76f967c6e97.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7937101125717163}",,,,,,,,,,['negative'],negative,0 NCT00731549,"{'position': 1, 'link': 'https://www.nature.com/articles/npjschz201539', 'title': 'Aripiprazole once-monthly 400 mg for long-term maintenance treatment of schizophrenia: a 52-week open-label study', 'source': 'Nature', 'date': 'Nov 4, 2015', 'snippet': 'This study assessed the long-term safety, tolerability, and maintenance of \nthe therapeutic effect of aripiprazole once-monthly 400 mg (AOM 400) in \npatients...', 'thumbnail': 'https://serpapi.com/searches/6722cd2fa86921c0f30bf7d6/images/001a90fcae3c486c26a82f24156e389f9223327da6622fc03700682ec960afda.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8929340243339539}",,,,,,,,,,['neutral'],neutral,1 NCT01975246,"{'position': 1, 'link': 'https://www.nature.com/articles/hr2016124', 'title': 'Effect of hydrochlorothiazide in addition to telmisartan/amlodipine combination for treating hypertensive patients uncontrolled with telmisartan/amlodipine: a randomized, double-blind study', 'source': 'Nature', 'date': 'Oct 20, 2016', 'snippet': 'The efficacy and safety of telmisartan 80 mg/amlodipine 5 mg plus \nhydrochlorothiazide 12.5 mg (T80/A5/H12.5) was examined for its ability \nto...', 'thumbnail': 'https://serpapi.com/searches/6722cd3a2da15704c0e29bb9/images/1b79b63d51ffae9ca438d0f662edd7fab350cec2c4cad3759ffff0f61afc5f3b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7973392605781555}",,,,,,,,,,['neutral'],neutral,1 NCT00304070,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/adrenocortical-cancer-excellent-outcomes-room-improvement-treatment/', 'title': '‘Excellent’ Outcomes and Room for Improvement in Pediatric Adrenocortical Carcinoma', 'source': 'Cancer Therapy Advisor', 'date': 'Aug 13, 2021', 'snippet': 'Disease stage is significantly associated with outcomes in pediatric \npatients with adrenocortical carcinoma, a study suggests.', 'thumbnail': 'https://serpapi.com/searches/6722cdfb2c566da2e23fcd5c/images/cf780e2056ba580bb624b84ba1ce58ca3a5c1c3571c8b0acfd0903d31b579aff.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.566736102104187}",,,,,,,,,,['neutral'],neutral,1 NCT03009019,"{'position': 1, 'link': 'https://www.neurologyadvisor.com/news/celecoxib-effective-migraine-pain-relief-symptoms-aura-status-ahs-2022/', 'title': 'Celecoxib Effective for Migraine Pain Relief, Symptoms Regardless of Aura Status', 'source': 'Neurology Advisor', 'date': 'Jun 15, 2022', 'snippet': 'Oral celecoxib is more effective than placebo for the treatment of acute \nmigraine with or without aura, according to a pooled analysis of data from \n2 clinical...', 'thumbnail': 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Migraine Treatment', 'source': 'Medical Professionals Reference', 'date': 'Feb 24, 2022', 'snippet': 'Elyxyb (celecoxib oral solution) is now available for the acute treatment \nof migraine with or without aura in adults.', 'thumbnail': 'https://serpapi.com/searches/6722ce888de63c891833e165/images/1bd348287a5ef4f28b641b9ef7a569b124c7ef0e6b22871dcefdf90dc03bd2d5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.773752748966217}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT02421094,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-022-01119-3', 'title': 'Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)', 'source': 'Nature', 'date': 'Aug 13, 2022', 'snippet': 'In this review, we discussed recent developments in etiology and \nprospective therapeutic targets, as well as pharmacological candidates in \npre/clinical trials...', 'thumbnail': 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The agent demonstrates consistent clinical and bacteriologic \neffects.', 'thumbnail': 'https://serpapi.com/searches/6722cf25bd7cf087401d4383/images/2dc7c8777e39eac5b81f4457aa14460b9f83c402cdc7750a47df2584947ab30f.png', 'sentiment': 'positive', 'sentiment_prob': 0.7753939628601074}",,,,,,,,,,['positive'],positive,1 NCT01037790,"{'position': 1, 'link': 'https://www.onclive.com/view/dr-karasic-on-palbociclib-in-esophageal-and-gastric-cancer', 'title': 'Dr. Karasic on Palbociclib in Esophageal and Gastric Cancer', 'source': 'OncLive', 'date': 'Jan 29, 2018', 'snippet': 'Thomas Karasic, MD, investigator at Penn Medicine, discusses the rationale \nbehind the phase II trial (NCT01037790) of palbociclib (Ibrance)...', 'thumbnail': 'https://serpapi.com/searches/6722cf439e5bd5d9a6fc200a/images/4a42f5272c63d865b8a45e493cf822ba3d82973a0ebffc76e702d1d490fed8bc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9411104917526245}",,,,,,,,,,['neutral'],neutral,1 NCT03244228,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/heptares-administers-alzheimers-therapy-htl0016878-to-first-phase-1-trial-participant/', 'title': ""Alzheimer's Therapy HTL0016878 Is Being Administered to First Participant in Phase 1 Trial"", 'source': ""Alzheimer's News Today"", 'date': 'Sep 5, 2017', 'snippet': ""The first participant in a Phase 1 clinical trial of HTL0016878 as a \ntreatment for cognitive impairment in Alzheimer's disease is receiving the \ntherapy."", 'thumbnail': 'https://serpapi.com/searches/6722cf4facf7f8296777e777/images/5be6cfa19be8c6b44b1180cf85f1f3e54c27aae8758951ad38a2727954057c33.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8841114044189453}",,,,,,,,,,['neutral'],neutral,1 NCT02594371,"{'position': 1, 'link': 'https://breastcancer-news.com/2020/09/03/fda-reviewing-oral-paclitaxel-combo-as-metastatic-breast-cancer-treatment/', 'title': 'FDA Reviewing Oral Paclitaxel Combo as Metastatic Breast Cancer Treatment', 'source': 'Breast Cancer News', 'date': 'Sep 3, 2020', 'snippet': 'The new drug application from Athenex for oral Paclitaxel has been granted \npriority review. A decision is expected in 2021.', 'thumbnail': 'https://serpapi.com/searches/6722cf7954163d58f718d36f/images/e882d59bc8ad69b89b89d0579178b052463e1a01033ae04907d1c3a984e86ca3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8881188035011292}",,,,,,,,,,['neutral'],neutral,1 NCT02902029,"{'position': 1, 'link': 'https://www.onclive.com/view/early-switch-therapy-to-atezolizumab-after-vemurafenib-cobimetinib-run-in-improves-os-in-braf-v600-positive-melanoma', 'title': 'Early Switch Therapy to Atezolizumab After Vemurafenib/Cobimetinib Run-in Improves OS in BRAF V600–Positive Melanoma', 'source': 'OncLive', 'date': '1 month ago', 'snippet': 'Early switch therapy to atezolizumab after run-in with vemurafenib plus \ncobimetinib led to improved 4- and 5-month OS rates in BRAF V600–positive \nmelanoma.', 'thumbnail': 'https://serpapi.com/searches/6722cfd4bb55ffdd70c730e6/images/089f0dc49bd3e0c66b8e2b67cd0d09ee4c8c3be590a4f18112182000a1fffde8.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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Cedazuridine Wins EU Approval for Newly Diagnosed AML', 'source': 'OncLive', 'date': 'Sep 19, 2023', 'snippet': 'The European Commission has approved oral decitabine and cedazuridine for \nthe treatment of adult patients with newly diagnosed acute myeloid...', 'thumbnail': 'https://serpapi.com/searches/6722d008717bff9194f9f6f0/images/6c890e53293bf62484cb28ac76aacd1ea7d315a014326095f89402dddbde27c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8428905010223389}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/ema-accepts-marketing-authorization-application-for-decitabine-and-cedazuridine-in-adult-aml', 'title': 'EMA Accepts Marketing Authorization Application for Decitabine and Cedazuridine in Adult AML', 'source': 'Cancer Network', 'date': 'Aug 24, 2022', 'snippet': 'Adult patients with acute myeloid leukemia who are not eligible for \ntreatment with standard induction chemotherapy may benefit from...', 'thumbnail': 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'title': 'Efficacy and safety of aticaprant, a kappa receptor antagonist, adjunctive to oral SSRI/SNRI antidepressant in major depressive disorder: results of a phase 2 randomized, double-blind, placebo-controlled study', 'source': 'Nature', 'date': 'Apr 22, 2024', 'snippet': 'This was a double-blind, randomized, phase 2 study of adults (18–64 years) \nwith DSM−5 diagnosis of major depressive disorder (MDD),...', 'thumbnail': 'https://serpapi.com/searches/6722d0ba29e6fbf3605b13b7/images/0cfc281aab9131fc67148bf58da8d5bc12e7689ea42ac399c173083e937d4dfa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8731998205184937}",,,,,,,,,,['neutral'],neutral,1 NCT01387763,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/reports/myeloproliferative-neoplasm-mpn-hydroxyurea-outcomes-treatment-risk/', 'title': 'No Significant Differences in Outcomes Seen Between Hydroxyurea and IFNα in Patients With MPNs', 'source': 'Hematology Advisor', 'date': 'Dec 12, 2023', 'snippet': 'The final analysis of the DALIAH trial (ClinicalTrials.gov Identifier: \nNCT01387763), which was presented at the ASH Annual Meeting 2023,...', 'thumbnail': 'https://serpapi.com/searches/6722d0c87b05caaa903b5e85/images/b6ed9452bdcf1b312f5221a8bab47e47265956b333f74377153cd246ce8ec354.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8983315825462341}",,,,,,,,,,['neutral'],neutral,1 NCT05158023,"{'position': 1, 'link': 'https://nationaleczema.org/blog/aslan-12122/', 'title': 'ASLAN Pharmaceuticals initiates Phase 2b study of ASLAN004 (eblasakimab) in moderate-to-severe atopic dermatitis', 'source': 'National Eczema Association', 'date': 'Feb 10, 2022', 'snippet': 'The randomized, double-blind, placebo-controlled, dose-ranging clinical \nstudy will evaluate the efficacy and safety of eblasakimab in adult \npatients with...', 'thumbnail': 'https://serpapi.com/searches/6722d0ffe30abc8601a29b1b/images/f42035aab07052c0a8af5a6e6b7bf18394fcf72152151cb3d9673f47db0e8e3b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8525307774543762}",,,,,,,,,,['neutral'],neutral,1 NCT02265705,"{'position': 1, 'link': 'https://rheumatoidarthritisnews.com/baricitinib-olumiant-for-rheumatoid-arthritis/', 'title': 'Baricitinib (Olumiant) for Rheumatoid Arthritis', 'source': 'Rheumatoid Arthritis News', 'date': 'Apr 24, 2017', 'snippet': 'Read about Baricitinib (Olumiant), which inhibits the inflammation \nassociated with rheumatoid arthritis, easing the joint pain that stems from \nthe disease.', 'thumbnail': 'https://serpapi.com/searches/6722d1334677bf0ea03abea1/images/acf114c5e4dd1729c8e2f4f098ec85a833387c00e31cbf3e7104c40298db017a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7946578860282898}",,,,,,,,,,['neutral'],neutral,1 NCT01791153,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1613849', 'title': 'Trial of Tocilizumab in Giant-Cell Arteritis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 27, 2017', 'snippet': 'Giant-cell arteritis commonly relapses when glucocorticoids are tapered, \nand the prolonged use of glucocorticoids is associated with side...', 'thumbnail': 'https://serpapi.com/searches/6722d149d72128a1d3459d82/images/d54102965f7791e7c23ed27a6d9950880addf75d79e053c810ffdaf323fee7ef.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6366521716117859}",,,,,,,,,,['neutral'],neutral,1 NCT03536728,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02525-2', 'title': 'Phase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial | British Journal of Cancer', 'source': 'Nature', 'date': 'Jan 10, 2024', 'snippet': 'MYC genes regulate ornithine decarboxylase (Odc) to increase intratumoral \npolyamines. We conducted a Phase I trial [NCT02030964] to...', 'thumbnail': 'https://serpapi.com/searches/6722d3191f3d4bf318db2e4c/images/84d52b915665ddba9ed3aae3e442c4a8b4f2476557441a4f27f11e75192d0edd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8940494656562805}",,,,,,,,,,['neutral'],neutral,1 NCT01144338,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1612917', 'title': 'Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Sep 14, 2017', 'snippet': 'The cardiovascular effects of adding once-weekly treatment with exenatide \nto usual care in patients with type 2 diabetes are unknown.', 'thumbnail': 'https://serpapi.com/searches/6722d4285ed3cab1ee1c0573/images/65c65e56915ff0ad35b692a511eed46e2a09a8c6edb7e1545201fd17fed403ea.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7171388268470764}",,,,,,,,,,['neutral'],neutral,1 NCT04242446,"{'position': 1, 'link': 'https://www.ajmc.com/view/bimekizumab-elicits-clinically-meaningful-responses-in-moderate-to-severe-hidradenitis-suppurativa', 'title': 'Bimekizumab Elicits Clinically Meaningful Responses in Moderate to Severe Hidradenitis Suppurativa', 'source': 'AJMC', 'date': 'May 24, 2024', 'snippet': 'In newly published findings from the pivotal phase 3 BE HEARD I \n(NCT04242446) and BE HEARD II (NCT04242498) trials, bimekizumab was well...', 'thumbnail': 'https://serpapi.com/searches/6722d4449062f8d4f3792369/images/606181fd0c5c2de2525faed887fb07d61ee73303de8267bfeaebbd27492f3cb3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6742416024208069}",,,,,,,,,,['neutral'],neutral,1 NCT04115488,"{'position': 1, 'link': 'https://www.empr.com/home/news/generics-news/fda-approves-biosimilar-tyruko-for-multiple-sclerosis-crohn-disease/', 'title': 'FDA Approves Biosimilar Tyruko for Multiple Sclerosis, Crohn Disease', 'source': 'Medical Professionals Reference', 'date': 'Aug 25, 2023', 'snippet': 'The Food and Drug Administration has approved Tyruko (natalizumab-sztn), a \nbiosimilar to Tysabri (natalizumab).', 'thumbnail': 'https://serpapi.com/searches/6722d48bf9f90434f5ac6fb6/images/abbc521a6ad69595257f79badc348a79717b17999226cde86fa90513ff366e32.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6632517576217651}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/02/03/biosimilar-pb006-comparable-safety-efficacy-tysabri-phase-3/', 'title': 'Biosimilar Comparable in Safety, Efficacy to Tysabri in Phase 3 Trial', 'source': 'Multiple Sclerosis News Today', 'date': 'Feb 3, 2023', 'snippet': 'PB006, a biosimilar to Tysabri, showed similar safety and efficacy as the \noriginal medication in people with RRMS in a Phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/6722d48bf9f90434f5ac6fb6/images/abbc521a6ad695959ac146dd87be94876a2f220a2111d9dcbad966e1691a7914.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5543018579483032}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/07/19/natalizumab-tysabri-biosimilar-ms-approval-review-europe/', 'title': 'Natalizumab, Tysabri Biosimilar, Up for Approval in Europe |...', 'source': 'Multiple Sclerosis News Today', 'date': 'Jul 19, 2022', 'snippet': ""The European Medicines Agency will consider for approval Polpharma \nBiologics' natalizumab, an MS antibody therapy similar to Tysabri."", 'thumbnail': 'https://serpapi.com/searches/6722d48bf9f90434f5ac6fb6/images/abbc521a6ad69595bc5b573acc3a1bf37bde2b66abaaf19305adbe2fb1c4e318.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9038274884223938}","{'position': 4, 'link': 'https://multiplesclerosisnewstoday.com/tyruko-first-tysabri-biosimilar-approved-europe-rmms/', 'title': 'Tyruko, first Tysabri biosimilar, approved in Europe for RMMS –...', 'source': 'Multiple Sclerosis News Today', 'date': 'Sep 28, 2023', 'snippet': 'The European Commission has approved Tyruko, the first biosimilar of \nTysabri, for the treatment of adults with highly active RRMS.', 'thumbnail': 'https://serpapi.com/searches/6722d48bf9f90434f5ac6fb6/images/abbc521a6ad69595fe926d21aacbd6a971def092d973048a01ebf18cb841dcfb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6000606417655945}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00405756,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1112704', 'title': 'Continuous Lenalidomide Treatment for Newly Diagnosed Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'May 10, 2012', 'snippet': 'Lenalidomide has tumoricidal and immunomodulatory activity against multiple \nmyeloma. This double-blind, multicenter, randomized study...', 'thumbnail': 'https://serpapi.com/searches/6722d49c76079d5760ef546d/images/dea5ff2b02c5f46926d23c1e38b9831a85c4074c1d44265e270bf08718efa2ab.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9088589549064636}",,,,,,,,,,['neutral'],neutral,1 NCT00109499,"{'position': 1, 'link': 'https://www.cureus.com/articles/110149-ocular-gene-therapy-a-literature-review-with-focus-on-current-clinical-trials', 'title': 'Ocular Gene Therapy: A Literature Review With Focus on Current Clinical Trials', 'source': 'Cureus', 'date': 'Sep 24, 2022', 'snippet': 'Gene therapy has been one of the most researched topics in the last decade. \nIt has now become a revolutionized therapeutic tool of modern...', 'thumbnail': 'https://serpapi.com/searches/6722d5fb2fab620db4097b0f/images/1b48f780a923ff4befdb81b057fd3a13489ce4b21ba9b9f8f46279132a4b2ab6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8775461316108704}",,,,,,,,,,['positive'],positive,1 NCT03851146,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-23331-5', 'title': 'CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy', 'source': 'Nature', 'date': 'May 28, 2021', 'snippet': 'Here we show that targeting A 2A R with a clinically relevant CRISPR/Cas9 \nstrategy significantly enhances their in vivo efficacy, leading to improved \nsurvival...', 'thumbnail': 'https://serpapi.com/searches/6722d65e0a545a3021a89822/images/d905aafdd4ff06690f71b83f3ace0c9736893287c4c870ca3c5047e13096653f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5505958795547485}",,,,,,,,,,['neutral'],neutral,1 NCT02387996,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/nivolumab-ipilimumab-boosts-improves-responses-in-bladder-cancer-non-responders', 'title': 'Nivolumab/Ipilimumab Boosts Improves Responses in Bladder Cancer Non-Responders', 'source': 'Cancer Network', 'date': 'Apr 28, 2023', 'snippet': 'Data from the phase 2 TITAN-TCC trial suggest that early non-responders \nwith metastatic urothelial carcinoma with PD-L1–positive tumors...', 'thumbnail': 'https://serpapi.com/searches/6722d69eee46823f19e99300/images/9f92583875f9fcf1cd880133cb4f74cc4039fec00a1599ec239bf6caa7173c2c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7841391563415527}",,,,,,,,,,['neutral'],neutral,1 NCT04079803,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/pti-125-fails-lower-csf-protein-levels-alzheimers-patients-phase-2-trial/', 'title': 'PTI-125 Fails to Lower Alzheimer’s Protein Levels in Phase 2 Trial', 'source': ""Alzheimer's News Today"", 'date': 'May 18, 2020', 'snippet': ""Cassava Sciences announced PTI-125 failed to significantly lower levels of \nAlzheimer's-relevant markers, a primary trial goal, and data are..."", 'thumbnail': 'https://serpapi.com/searches/6722d7498a7c09ea79016cf0/images/df29584baa8b93f1b3c98c10ae56790d8cea4743d913a6926a1b82e291122715.jpeg', 'sentiment': 'negative', 'sentiment_prob': 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lymphoma clinical trial', 'source': 'Lymphoma Hub', 'date': 'Jul 5, 2019', 'snippet': 'The U.S. Food and Drug Administration has decided to place on hold clinical \ntrial ATTCK-20-2 investigating an experimental T-cell therapy...', 'thumbnail': 'https://serpapi.com/searches/6722d7aacf32e0735598dc05/images/50a24013534257995cd490e5f1f1ab512af1c520fccd88524160421096bfe0f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.509852409362793}",,,,,,,,,,['neutral'],neutral,1 NCT00844545,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1208981', 'title': 'Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome', 'source': 'The New England Journal of Medicine', 'date': 'Apr 15, 2018', 'snippet': 'Atypical hemolytic–uremic syndrome is a genetic, life-threatening, chronic \ndisease of complement-mediated thrombotic microangiopathy.', 'thumbnail': 'https://serpapi.com/searches/6722d95b690bb9df0c32f8f5/images/dbb74919b7b3b2fe457ef5ad27060f0515d17cd4ed600b55fcd28049a8aba13f.png', 'sentiment': 'negative', 'sentiment_prob': 0.5254178047180176}",,,,,,,,,,['negative'],negative,0 NCT00273364,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/autologous-stem-cell-transplant-safe-effective-rrms-study/', 'title': 'Stem cell therapy found safe, effective in RRMS study', 'source': 'Multiple Sclerosis News Today', 'date': 'Sep 29, 2023', 'snippet': 'About three quarters of relapsing MS patients did not show signs of disease \nactivity five years after an autologous stem cell transplant.', 'thumbnail': 'https://serpapi.com/searches/6722d96496a329d9498ff292/images/3153d3ff322a4f7a24335ff0dc2f45ec01afe2912a2a2c30ae322d69befb9c92.png', 'sentiment': 'positive', 'sentiment_prob': 0.5159249305725098}","{'position': 2, 'link': 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2020', 'snippet': 'Multi-institute NIH study suggests that the HPV vaccine could protect women \nagainst new HPV infections after stem cell transplantation.', 'thumbnail': 'https://serpapi.com/searches/6722d9a7d364b477d7d0173e/images/6210aff57801fd7f4258ecdbd51d3c0b8b6fe95b98bde894d7f49b5c7adab8f2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.49816372990608215}",,,,,,,,,,['positive'],positive,1 NCT02554773,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/fda-lifts-clinical-hold-fitusiran-hemophilia-therapy/', 'title': 'FDA Lifts Clinical Hold on Fitusiran, an Investigational...', 'source': 'Hemophilia News Today', 'date': 'Dec 20, 2017', 'snippet': 'The U.S. Food and Drug Administration (FDA) has lifted the hold on clinical \nstudies with fitusiran, an investigational therapy for...', 'thumbnail': 'https://serpapi.com/searches/6722d9a8f3622a724e9bebd6/images/0004fe532cfeee0906fd6c5b7e95d7e5f9e8d17d87dc93e6424a834e87f0622c.jpeg', 'sentiment': 'neutral', 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'title': 'Opdivo, Yervoy Combo Improved Survival in Advanced Melanoma Phase 3 Trial', 'source': 'Melanoma News Today', 'date': 'Apr 6, 2017', 'snippet': 'Opdivo (nivolumab) in combination with Yervoy (ipilimumab), as well as \nOpdivo alone, outperformed Yervoy monotherapy in terms of overall survival \nin a Phase 3...', 'thumbnail': 'https://serpapi.com/searches/6722db2d2fab620d6b1e388b/images/f914252b7a637ee8b81671a6011009df1fda2eef00ffbe1de0c57b16669b8a8a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5838354229927063}","{'position': 4, 'link': 'https://melanomanewstoday.com/2016/10/20/keytruda-pembrolizumab-plus-yervoy-ipilimumab-seen-as-safe-effective-for-advanced-melanoma-in-study/', 'title': 'Advanced Melanomas Seen to Respond to Keytruda-Yervoy Combo in Study', 'source': 'Melanoma News Today', 'date': 'Oct 20, 2016', 'snippet': 'Data from a Phase 1/2 study found a Keytruda-Yervoy combination to have \npotent anti-tumor activity and acceptable toxicity in advanced...', 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'https://www.stocktitan.net/news/RHHBY/roche-s-vabysmo-improved-vision-in-underrepresented-populations-with-y3hygys486ou.html', 'title': 'Roche’s Vabysmo improved vision in underrepresented populations with diabetic macular edema (DME) in a first-of-its-kind study', 'source': 'Stock Titan', 'date': '2 weeks ago', 'snippet': 'Roche announced positive one-year results from the ELEVATUM study, \nevaluating Vabysmo® (faricimab) for diabetic macular edema (DME) in...', 'thumbnail': 'https://serpapi.com/searches/6722dc92a54d7e5ab852471a/images/339f67b270150f6c49588edb657a9a2f20c57663ff7ccb7fbe15e6bfb994f179.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7804692983627319}","{'position': 2, 'link': 'https://www.globenewswire.com/news-release/2024/07/30/2920702/0/en/European-Commission-approves-Roche-s-Vabysmo-for-treatment-of-retinal-vein-occlusion-RVO.html', 'title': 'European Commission approves Roche’s Vabysmo for treatment of retinal vein occlusion (RVO)', 'source': 'GlobeNewswire', 'date': 'Jul 30, 2024', 'snippet': 'Approval is based on data from two Phase III studies in branch and central \nretinal vein occlusion (RVO) showing early and sustained vision...', 'thumbnail': 'https://serpapi.com/searches/6722dc92a54d7e5ab852471a/images/339f67b270150f6cb094c64f404d452b56065f65ed2344eb32a6c10e826dc2d0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6009171605110168}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00887328,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1813046', 'title': 'Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke', 'source': 'The New England Journal of Medicine', 'date': 'May 8, 2019', 'snippet': 'The time to initiate intravenous thrombolysis for acute ischemic stroke is \ngenerally limited to within 4.5 hours after the onset of symptoms.', 'thumbnail': 'https://serpapi.com/searches/6722dcd672e5c43d37cf3d95/images/92e20b1abc4d6d2ddba593316438e680369b72dccbc173fdf00eeefb4fc887cd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8518437743186951}",,,,,,,,,,['neutral'],neutral,1 NCT04000594,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/news/generation-hd1-trial-fails-to-demonstrate-benefits-tominersen/', 'title': 'GENERATION HD1 Trial Fails to Show Benefits of Tominersen', 'source': ""Huntington's Disease News"", 'date': 'May 6, 2021', 'snippet': ""Treatment with tominersen failed to show evidence of clinical benefit in \nadults with Huntington's disease during the Phase 3 trial..."", 'thumbnail': 'https://serpapi.com/searches/6722dd1098fad63805a90f3f/images/a63e7f6b7e4cab068c9af1874379de31b7c8c5f0206fd21a87ceb50f8b2cad4c.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7655267715454102}",,,,,,,,,,['negative'],negative,0 NCT01227655,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/analyst-comment/ean-2024-opicapone-efficacy-real-world-clinical-practice/', 'title': 'EAN 2024: Opicapone demonstrates efficacy in real-world clinical practice', 'source': 'Clinical Trials Arena', 'date': 'Jul 5, 2024', 'snippet': 'At EAN, Dr Maria-Rosario Luquin presented the results of the 12-month, \nobservational, retrospective OPTIMO study.', 'thumbnail': 'https://serpapi.com/searches/6722dd619872170750981ad9/images/4e0f530c5824ecd1e30d2e6fe60d14c5752488420cd6bfcf201c859a277a538a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5519387125968933}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/new-data-support-effectiveness-of-ongentys-for-parkinsons-off-periods/', 'title': 'New Data Support Effectiveness of Ongentys for Parkinson’s ‘Off’ Periods', 'source': ""Parkinson's News Today"", 'date': 'Oct 6, 2020', 'snippet': ""Ongentys (opicapone) can reduce the extent of “off” periods in people with \nParkinson's disease being treated with levodopa, new clinical trial data \nshow."", 'thumbnail': 'https://serpapi.com/searches/6722dd619872170750981ad9/images/4e0f530c5824ecd1ab715a12ab925a9eaf8354e177730001794b83a37ec405bf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8502773642539978}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT01072266,"{'position': 1, 'link': 'https://www.nature.com/articles/srep11749', 'title': 'INC280, an orally available small molecule inhibitor of c-MET, reduces migration and adhesion in ovarian cancer cell models', 'source': 'Nature', 'date': 'Jul 3, 2015', 'snippet': 'The objective of this study was to determine the efficacy of a novel, \nhighly potent, orally-bioavailable c-MET inhibitor, INC280, in blocking \ncell phenotypes...', 'thumbnail': 'https://serpapi.com/searches/6722ddcec0028e6e4e04f9a3/images/2d5adff31dc77be5c043977e23e36c8d52fe11d804cdd6d78a095bc37d52ee45.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8308812379837036}",,,,,,,,,,['neutral'],neutral,1 NCT01636622,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-022-00341-0', 'title': 'BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study | npj Precision Oncology', 'source': 'Nature', 'date': 'Feb 18, 2023', 'snippet': 'We performed a pooled analysis of four phase one studies evaluating the \nsafety and efficacy of vemurafenib monotherapy and vemurafenib combined \nwith targeted...', 'thumbnail': 'https://serpapi.com/searches/6722de43a32436a16214aab2/images/21ee6dace00080128be9cc62912362013d6da5a6044fcdc80b75d81059317f99.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9065907597541809}",,,,,,,,,,['neutral'],neutral,1 NCT04018755,"{'position': 1, 'link': 'https://sanfilipponews.com/news/individualized-trials-sanfilippo-anti-inflammatory-therapies-sought/', 'title': 'Individualized trials of Sanfilippo anti-inflammatory therapies sought', 'source': 'Sanfilippo Syndrome News', 'date': 'Jul 6, 2023', 'snippet': 'Researchers are calling for individualized clinical trials that would test \nthe effects of anti-inflammatory therapies for Sanfilippo syndrome and \nrelated...', 'thumbnail': 'https://serpapi.com/searches/6722de66749783416cf3e947/images/b17f50999a62ec7bc4d4e88b1d2f5951d7c3f5037186927e8ec4757a3bc34ebe.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9001984596252441}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/abs/10.1111/jnc.15891', 'title': 'Biomarkers for predicting disease course in Sanfilippo syndrome: An urgent unmet need in childhood-onset dementia', 'source': 'Wiley Online Library', 'date': 'Jun 26, 2023', 'snippet': 'In this review, we discuss the development of biomarker assays for \nSanfilippo based on the neuropathological pathways known to change leading \ninto symptom...', 'thumbnail': 'https://serpapi.com/searches/6722de66749783416cf3e947/images/b17f50999a62ec7bdbe70ccec1ec23926f845b2d0a8805a3f8dd90106e37ef1d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8570588827133179}","{'position': 3, 'link': 'https://sanfilipponews.com/news/anakinra-approved-kineret-for-inflammatory-disorders-in-phase-2-3-trial-for-sanfilippo/', 'title': 'Anakinra, Approved as Anti-inflammatory, in Phase 2/3 Trial for...', 'source': 'Sanfilippo Syndrome News', 'date': 'Jun 25, 2020', 'snippet': 'An ongoing clinical trial is investigating an approved anti-inflammatory \ncompound anakinra, sold under the brand name Kineret, as a potential \ntreatment for...', 'thumbnail': 'https://serpapi.com/searches/6722de66749783416cf3e947/images/b17f50999a62ec7b9d6dcc7b719dfe56f55b4c3661dd579c96f465591282b1f8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8642048835754395}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02472795,"{'position': 1, 'link': 'https://lupusnewstoday.com/news/cenerimod-shows-promise-sle-phase-2b-study-phase-3-begins/', 'title': 'Cenerimod Shows Promise for SLE in Phase 2b Study; Phase 3 Begins...', 'source': 'Lupus News Today', 'date': 'Dec 19, 2022', 'snippet': 'Treatment with cenerimod showed promising trends toward reducing disease \nactivity in systemic lupus erythematosus (SLE), especially in people with \nmore severe...', 'thumbnail': 'https://serpapi.com/searches/6722df05d78a985ac5d5a0be/images/2827d11b3e855ef3c2a04db21d66ca18f633e36e4f175f2c51e8189bbca85d95.png', 'sentiment': 'positive', 'sentiment_prob': 0.7075773477554321}",,,,,,,,,,['positive'],positive,1 NCT02267655,"{'position': 1, 'link': 'https://copdnewstoday.com/news/pulmonary-hypertension-associated-with-chronic-obstructive-pulmonary-disease-investigational-therapy-inopulse-shows-positive-results-bellerophon-says/', 'title': 'PH-COPD Investigational Therapy INOpulse Shows Positive Phase 2 Results, Bellerophon Says', 'source': 'COPD News Today', 'date': 'Sep 12, 2017', 'snippet': 'INOpulse as a therapy for pulmonary hypertension associated with chronic \nobstructive pulmonary disease (PH-COPD) showed promising results in a Phase \n2 clinical...', 'thumbnail': 'https://serpapi.com/searches/6722df1088bcdeacaef27e57/images/649a1cda862d08576a0f86cc4e3905b0f3c9bb3decc099e03e5b40cb515892a5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5401460528373718}",,,,,,,,,,['positive'],positive,1 NCT05603754,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01330-w', 'title': 'Osteoarthritis: pathogenic signaling pathways and therapeutic targets', 'source': 'Nature', 'date': 'Feb 3, 2023', 'snippet': 'Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to \ndisability and affects more than 500 million population worldwide...', 'thumbnail': 'https://serpapi.com/searches/6722df2fee46823ed9bdd89e/images/74b64f9d8801b26554ec345b43e76128a9681ed2f92a285e2eaaf5c4b5453089.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7383952736854553}",,,,,,,,,,['negative'],negative,0 NCT05558410,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209870', 'title': 'Selective Inhibition of NaV1.8 with VX-548 for Acute Pain', 'source': 'The New England Journal of Medicine', 'date': 'Aug 2, 2023', 'snippet': 'The NaV1.8 voltage-gated sodium channel, expressed in peripheral \nnociceptive neurons, plays a role in transmitting nociceptive signals.', 'thumbnail': 'https://serpapi.com/searches/6722df41b4e8d6ba085f4a84/images/4e886f38544a67a6febecf07ad71698344192a6f53a798c228d572879bcb81e7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8272075057029724}",,,,,,,,,,['neutral'],neutral,1 NCT01170897,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-62470-9', 'title': 'Magnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials', 'source': 'Nature', 'date': 'May 21, 2024', 'snippet': 'Pre-clinical and clinical studies have shown that PEGPH20 depletes \nintratumoral hyaluronic acid (HA), which is linked to high interstitial...', 'thumbnail': 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'https://myelomaresearchnews.com/news/kyprolis-improved-survival-confirmed-latest-results/', 'title': 'Long-term Data Confirm Kyprolis Survival Benefit in Relapsed...', 'source': 'Myeloma Research News', 'date': 'Sep 6, 2017', 'snippet': 'New long-term data from the ENDEAVOR trial shows that Kyprolis plus \ndexamethasone extends the median survival by 9 months over Velcade in...', 'thumbnail': 'https://serpapi.com/searches/6722df76cf32e0739b20642e/images/646ceb3b67fe143280d50ea85b4ccc8e35747653259ab267303c181e9e8b0117.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5090252161026001}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02540993,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2025845', 'title': 'Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Oct 23, 2020', 'snippet': 'Finerenone, a nonsteroidal, selective mineralocorticoid receptor \nantagonist, reduced albuminuria in short-term trials involving patients \nwith chronic kidney...', 'thumbnail': 'https://serpapi.com/searches/6722df948b84c41a795d32f2/images/3e085d2cae9e87839eada3a55350dfaedbb4958574d3c013a4912e0c56d6b162.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8269692063331604}","{'position': 2, 'link': 'https://www.nature.com/articles/s41598-024-51938-3', 'title': 'A comparative study of clinical trial and real-world data in patients with diabetic kidney disease', 'source': 'Nature', 'date': 'Jan 19, 2024', 'snippet': 'A growing body of research is focusing on real-world data (RWD) to \nsupplement or replace randomized controlled trials (RCTs).', 'thumbnail': 'https://serpapi.com/searches/6722df948b84c41a795d32f2/images/3e085d2cae9e8783d125dd84910d83fc731f4fe562b0aa2d508eeb3da23dd0df.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9166094660758972}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04197479,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02603-1', 'title': 'Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial', 'source': 'Nature', 'date': 'Oct 16, 2023', 'snippet': 'Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with no \napproved treatment. MAESTRO-NAFLD-1 was a 52-week randomized,...', 'thumbnail': 'https://serpapi.com/searches/6722dfb5059cafd210267ffa/images/6f8a01af386ad7322b64bbbee61e0780b96a0caf3ac5915b986302481c001c41.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5281579494476318}","{'position': 2, 'link': 'https://www.hepmag.com/article/resmetirom-improves-nash-liver-fibrosis-phase-iii-trial', 'title': 'Resmetirom Improves NASH and Liver Fibrosis in Phase III Trial', 'source': 'www.hepmag.com', 'date': 'Jun 23, 2023', 'snippet': 'The findings could potentially lead to the first FDA approval of a \ntreatment for fatty liver disease.', 'thumbnail': 'https://serpapi.com/searches/6722dfb5059cafd210267ffa/images/6f8a01af386ad732f0145beeb03c2a802f76116ab4b2ee972f87872cc7e90035.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6385818123817444}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02654132,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1805762', 'title': 'Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'Nov 7, 2018', 'snippet': 'The immunostimulatory monoclonal antibody elotuzumab plus lenalidomide and \ndexamethasone has been shown to be effective in patients with relapsed or \nrefractory...', 'thumbnail': 'https://serpapi.com/searches/6722e0660664c9fe85c69022/images/1926f0ff383e62b7db9e7dec921b54b11af34dc4241b3b095b1bd7b80293b098.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7223803997039795}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/fda-approves-empliciti-combination-relapsed-refractory-multiple-myeloma/', 'title': 'FDA Approves Empliciti Combination for Relapsed or Refractory Multiple Myeloma', 'source': 'Myeloma Research News', 'date': 'Nov 12, 2018', 'snippet': ""The U.S. Food and Drug Administration has approved Bristol-Myers Squibb's \nEmpliciti (elotuzumab), in combination with Pomalyst..."", 'thumbnail': 'https://serpapi.com/searches/6722e0660664c9fe85c69022/images/1926f0ff383e62b70600c702fa8b66d182e5d3d9d9a29a60867ca3bbf634b612.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7444874048233032}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00414128,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/fatigue-persists-at-high-levels-in-some-aav-patients-despite-treatment-study-shows/', 'title': 'In Some AAV Patients, Fatigue Seen to Persist at High Levels Despite Treatment', 'source': 'ANCA Vasculitis News', 'date': 'Jul 11, 2019', 'snippet': 'A small subgroup can continue to have high fatigue levels, according to a \nstudy in 150 newly diagnosed patients who took part in clinical trials.', 'thumbnail': 'https://serpapi.com/searches/6722e08abe80133871049248/images/7d2e1163da4b5d6518f95f05297640cc1c9e81106899012faeb2dc2e8a54bb65.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6142919659614563}",,,,,,,,,,['neutral'],neutral,1 NCT03285178,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/cyclerion-suspends-development-of-olinciguat-for-sickle-cell-disease/', 'title': 'Cyclerion Suspends Development of Olinciguat for Sickle Cell Disease', 'source': 'Sickle Cell Disease News', 'date': 'Oct 20, 2020', 'snippet': ""Cyclerion Therapeutics' decisions about olinciguat was based top-line \nresults of the Phase 2 clinical trial STRONG-SCD (NCT03285178)."", 'thumbnail': 'https://serpapi.com/searches/6722e0a475f974affaee69b6/images/7715a7656ae9d8698f039a62a73a921aaf4958057338a71f69e9ef645a30c9c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.53346186876297}",,,,,,,,,,['neutral'],neutral,1 NCT03624127,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1111/1346-8138.16740', 'title': 'Efficacy and safety of the selective TYK2 inhibitor, deucravacitinib, in Japanese patients with moderate to severe plaque psoriasis: Subgroup analysis of a randomized, double‐blind, placebo‐controlled, global phase 3 trial - Imafuku - 2023 - The Journal of Der', 'source': 'Wiley Online Library', 'date': 'Mar 7, 2023', 'snippet': 'Deucravacitinib is an oral, selective, allosteric tyrosine kinase 2 (TYK2) \ninhibitor that demonstrated superior efficacy versus placebo and apremilast \nin a...', 'thumbnail': 'https://serpapi.com/searches/6722e0c8c0028e6e9896d3e0/images/f85a4a03d9e79cd4d4437f6eee2aed97d461c927365fd4c9e42d205694050bf8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8855554461479187}","{'position': 2, 'link': 'https://www.thepharmaletter.com/biotechnology/2-9-billion-in-sales-forecast-for-bms-sotyktu-by-2029', 'title': '$2.9 billion in sales forecast for BMS’ Sotyktu by 2029', 'source': 'The Pharma Letter', 'date': 'May 11, 2023', 'snippet': ""$2.9 billion in sales forecast for BMS' Sotyktu by 2029. Biotechnology. 11 \nMay 2023. bristol_myers_squibb_shutterstock_large."", 'thumbnail': 'https://serpapi.com/searches/6722e0c8c0028e6e9896d3e0/images/f85a4a03d9e79cd403eb03602d49f55454a75de03670e117498703dc472d040b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7873889207839966}","{'position': 3, 'link': 'https://www.empr.com/home/news/fda-approves-sotyktu-for-moderate-to-severe-plaque-psoriasis/', 'title': 'FDA Approves Sotyktu for Moderate to Severe Plaque Psoriasis', 'source': 'Medical Professionals Reference', 'date': 'Sep 12, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Sotyktu™ \n(deucravacitinib) for the treatment of adults with moderate to severe \nplaque...', 'thumbnail': 'https://serpapi.com/searches/6722e0c8c0028e6e9896d3e0/images/f85a4a03d9e79cd49211eb76522881f6544bde73318abcc2117857fa74681451.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7778393626213074}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02748837,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-16564-x', 'title': 'Determination of starting dose of the T cell-redirecting bispecific antibody ERY974 targeting glypican-3 in first-in-human clinical trial', 'source': 'Nature', 'date': 'Jul 19, 2022', 'snippet': 'Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody \nrecognizing glypican-3 and CD3, is in phase I clinical trials.', 'thumbnail': 'https://serpapi.com/searches/6722e0ef1397baa002ea04a4/images/7fc891f2e9aef903fd6248d05040069df274a203763002d0a15e2fd3ca6458c0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9179657697677612}","{'position': 2, 'link': 'https://www.nature.com/articles/nrd.2017.237', 'title': 'Bispecific antibody directs T cells to solid tumours', 'source': 'Nature', 'date': 'Nov 17, 2017', 'snippet': 'A new paper from Chugai Pharmaceutical uses a bispecific antibody, ERY974, \nto direct T cells to non-immunogenic tumours using expression of glypican 3 \n(GPC3)...', 'thumbnail': 'https://serpapi.com/searches/6722e0ef1397baa002ea04a4/images/7fc891f2e9aef903352c6860394b76300c2bd0c721cbf23aa34cee6d1baae5fe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.891222357749939}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04798586,"{'position': 1, 'link': 'https://www.oncnursingnews.com/view/elranatamab-induces-responses-in-patients-with-relapsed-refractory-multiple-myeloma-following-bcma-directed-therapy', 'title': 'Elranatamab Induces Responses in Patients With Relapsed/Refractory Multiple Myeloma Following BCMA-Directed Therapy', 'source': 'Oncology Nursing News', 'date': 'Jun 15, 2023', 'snippet': 'A pooled analyses of the phase 1 MagnetisMM-1 (NCT03269136), phase 1 \nMagnetisMM-2 (NCT04798586), phase 2 MagnetisMM-3 (NCT04649359),...', 'thumbnail': 'https://serpapi.com/searches/6722e0f4e335ec0759a45c49/images/272cbe2353d0d1c55da85a412a232cffc9bb29e91b0e8edabbf3d12e51374691.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9129993319511414}",,,,,,,,,,['neutral'],neutral,1 NCT02048488,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0503-9', 'title': 'A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas', 'source': 'Nature', 'date': 'Jun 20, 2019', 'snippet': 'Anaplastic lymphoma kinase (ALK) gene rearrangements are oncogenic drivers \nin non-small-cell lung cancer (NSCLC). 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It is not yet recruiting.', 'thumbnail': 'https://serpapi.com/searches/6722e176d78a985a6b5ae0f7/images/01ff39197298bb9999e99ce59488d4078347b15f0ff59536cd351238117ad455.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9094328880310059}",,,,,,,,,,['neutral'],neutral,1 NCT02643420,"{'position': 1, 'link': 'https://www.empr.com/home/news/rolvedon-approved-for-chemotherapy-induced-neutropenia/', 'title': 'Rolvedon Approved for Chemotherapy-Induced Neutropenia - MPR', 'source': 'Medical Professionals Reference', 'date': 'Sep 12, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Rolvedon™ \n(eflapegrastim-xnst) to decrease the incidence of infection, as manifested \nby...', 'thumbnail': 'https://serpapi.com/searches/6722e185b691a72daec180a3/images/1cbd7b54fc5f33693b5f9b54981358fc158886e3d22411a3f539e0273f6e14f4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8527393937110901}",,,,,,,,,,['neutral'],neutral,1 NCT02426359,"{'position': 1, 'link': 'http://www.biospectator.com/view/news_print.php?varAtcId=7298', 'title': ""Qurient, presented the P2a results for atopic dermatitis candidate 'Q301' at the AAD 2019"", 'source': '바이오스펙테이터', 'date': 'Mar 15, 2019', 'snippet': 'Qurient presented the P2a trial results for Q301, a topical treatment for \natopic dermatitis currently under Phase 2b, on the international stage.', 'thumbnail': 'https://serpapi.com/searches/6722e1a32fab620d6b1e3e9d/images/cfc387201ea0fe52b0c77cfb89549d18bd4f4b4b513d0895bb591cca147315cc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9321069121360779}",,,,,,,,,,['neutral'],neutral,1 NCT03406780,"{'position': 1, 'link': 'https://musculardystrophynews.com/news/dmd-three-years-cap-1002-still-showing-stabilized-arm-heart-function/', 'title': 'In DMD, three years of CAP-1002 still showing stabilized arm, heart function', 'source': 'Muscular Dystrophy News', 'date': 'Jun 6, 2024', 'snippet': 'Topline data from the Phase 3 HOPE-3 trial, which is testing CAP-1002 in \nDMD patients with impaired muscle function, is expected this year.', 'thumbnail': 'https://serpapi.com/searches/6722e1ae8db376c3e953fd26/images/ea7ef43a783fb9c7f3b38d9a8bdc502d3f23b1ae6c5037f36378181f6cc11c48.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8677300810813904}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/news/capricor-therapeutics-long-term-data-positive/', 'title': 'Capricor’s cell therapy shows three year benefit in DMD patients', 'source': 'Clinical Trials Arena', 'date': 'Jul 1, 2024', 'snippet': 'Capricor Therapeutics has announced its deramiocel cell therapy continues \nto be safe and effective after three years for Duchenne muscular dystrophy \n(DMD).', 'thumbnail': 'https://serpapi.com/searches/6722e1ae8db376c3e953fd26/images/ea7ef43a783fb9c7b6eee7bb5ee95bb9cab2764867761d24fe19b796bc9bad81.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8001108765602112}","{'position': 3, 'link': 'https://www.cgtlive.com/view/duchenne-muscular-dystrophy-cell-therapy-cap-1002-demonstrates-improvements-lvef', 'title': 'Duchenne Muscular Dystrophy Cell Therapy CAP-1002 Demonstrates Improvements in LVEF', 'source': 'CGTLive®', 'date': 'Jul 6, 2023', 'snippet': ""In terms of safety, Capricor Therapeutics' CAP-1002 was reported to be \nwell-tolerated."", 'thumbnail': 'https://serpapi.com/searches/6722e1ae8db376c3e953fd26/images/ea7ef43a783fb9c7e6869a8767b8f83e7a5285ab56fadadbc9c6a5b91143363b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7191162109375}",,,,,,,,"['neutral', 'positive', 'positive']",positive,1 NCT03872453,"{'position': 1, 'link': 'https://www.empr.com/home/news/zavzpret-nasal-spray-approved-for-acute-treatment-of-migraine/', 'title': 'Zavzpret Nasal Spray Approved for Acute Treatment of Migraine', 'source': 'Medical Professionals Reference', 'date': 'Mar 10, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Zavzpret™ (zavegepant) \nnasal 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'https://cysticfibrosisnewstoday.com/inhaled-mannitol-mucociliary-clearance/', 'title': 'Bronchitol (Mannitol)', 'source': 'Cystic Fibrosis News Today', 'date': 'Mar 22, 2021', 'snippet': 'Bronchitol (mannitol), by Pharmaxis, is a dry powder inhalation treatment \nfor cystic fibrosis, approved in the U.S., EU,...', 'thumbnail': 'https://serpapi.com/searches/6722e2015ed3cab1a3eac4c3/images/c934317d6a94a65bd4b702fcb1e2417b23ff873a26487dc479024440838986aa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9064784049987793}",,,,,,,,,,['neutral'],neutral,1 NCT03556358,"{'position': 1, 'link': 'https://www.oncozine.com/samsung-bioepis-and-merck-launch-trastuzumab-biosimilar-in-the-united-states/', 'title': 'Samsung Bioepis and Merck Launch Trastuzumab Biosimilar in the United States.', 'source': ""Onco'Zine"", 'date': 'Apr 15, 2020', 'snippet': 'Samsung Bioepis, a joint venture of Samsung Biologics and Biogen, and Merck \n& Co (MSD) have lauched a trastuzumab biosimilar...', 'thumbnail': 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APHINITY is a prospective phase III study evaluating the role...', 'source': 'ResearchGate', 'date': 'Feb 11, 2018', 'snippet': 'Download scientific diagram | APHINITY is a prospective phase III study \nevaluating the role of trastuzumab plus pertuzumab combination versus \ntrastuzumab...', 'thumbnail': 'https://serpapi.com/searches/6722e2cd861b9dc3d5d8c9e5/images/8de0c3bdef9323424edfffb42218712985bed303bd340f2e136fa2b8db93f6cf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9367532730102539}",,,,,,,,,,['neutral'],neutral,1 NCT05020249,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/bimekizumab-UCB4940', 'title': 'Bimekizumab (Bimzelx®)', 'source': 'UCB', 'date': 'Oct 16, 2018', 'snippet': 'Ankylosing Spondylitis, A Multicenter Study to Evaluate the Efficacy and \nSafety of Different Doses of Bimekizumab in Subjects With Active \nAnkylosing...', 'thumbnail': 'https://serpapi.com/searches/6722e31ce30abc864c264649/images/eab8bd70dc1267d52ee1cf72ff89e5b57679bf378fdb6d3745291318b5c4266a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8456552028656006}",,,,,,,,,,['neutral'],neutral,1 NCT01938443,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0452-3', 'title': 'A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours', 'source': 'Nature', 'date': 'Apr 17, 2019', 'snippet': 'Combined focal adhesion kinase (FAK) and MEK inhibition may provide greater \nanticancer effect than FAK monotherapy. This dose-finding phase...', 'thumbnail': 'https://serpapi.com/searches/6722e36498d8de1868aaa9c1/images/5117133d8d159f633a0b2bf84883929920261da4003dc2b9492a4f65775a5dbb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8846467733383179}",,,,,,,,,,['neutral'],neutral,1 NCT00441337,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332218364102', 'title': 'PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer', 'source': 'ScienceDirect.com', 'date': 'Dec 3, 2018', 'snippet': 'We present a comprehensive knowledge of immune therapy through PD-1/PD-L1 \nblockade that argues how efficient the process is, in colon cancer \ncarcinoma.', 'thumbnail': 'https://serpapi.com/searches/6722e371fc40bfd05b71e72b/images/da6a7dc48cc373e20e69863324a651f292cb6363dfda6fcd464b384df75bdb9f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5837924480438232}",,,,,,,,,,['neutral'],neutral,1 NCT04553068,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/vaginal-ph-modulator-misses-primary-endpoint-in-sti-clinical-trial/', 'title': 'Vaginal pH Modulator Misses Primary Endpoint in STI Clinical Trial', 'source': 'Medical Professionals Reference', 'date': 'Oct 12, 2022', 'snippet': 'Topline results were announced from a phase 3 trial evaluating EVO100 for \nthe prevention of urogenital Chlamydia trachomatis (CT) and Neisseria \ngonorrhoeae (GC...', 'thumbnail': 'https://serpapi.com/searches/6722e37b8e13c9aa82df7a54/images/affb3a5afd5500b11258bf9ad48eca39ba1191e474f9201aefc886fe682b870d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.85575932264328}",,,,,,,,,,['neutral'],neutral,1 NCT02550652,"{'position': 1, 'link': 'https://lupusnewstoday.com/news/gazyva-lupus-nephritis-treatment-boosts-standard-care/', 'title': 'Gazyva, lupus nephritis treatment, boosts standard care in Phase 2 trial', 'source': 'Lupus News Today', 'date': 'Nov 27, 2023', 'snippet': 'Adding Gazyva (obinutuzumab) to standard-of-care therapy for two years \nreduced the risk of treatment failure, diminished kidney function or death \nby 60% in...', 'thumbnail': 'https://serpapi.com/searches/6722e39c7d533e6b3c105406/images/0aae74cac3066f00cedf95ed126cd98c36be5f47fc5a6d29d70211a41c443f82.png', 'sentiment': 'positive', 'sentiment_prob': 0.5715087652206421}",,,,,,,,,,['positive'],positive,1 NCT01969838,"{'position': 1, 'link': 'https://www.pharmacytimes.com/view/lead-investigator-provides-insight-into-fda-approval-of-momelotinib-for-myelofibrosis', 'title': 'Lead Investigator Provides Insight Into FDA Approval of Momelotinib for Myelofibrosis', 'source': 'Pharmacy Times', 'date': 'Sep 29, 2023', 'snippet': 'The FDA recently approved momelotinib to treat myelofibrosis in patients \nwith anemia based on data from the MOMENTUM and SIMPLIFY-1 trials.', 'thumbnail': 'https://serpapi.com/searches/6722e3d4acf7f8291ac533bd/images/934e093614527ab0e18ff5827f3d6035359b6de0c7ddc7f367727fdb715a404c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8080514073371887}","{'position': 2, 'link': 'https://www.hematologyadvisor.com/cch/ojjaara-for-intermediate-or-high-risk-myelofibrosis/', 'title': 'Ojjaara for Intermediate or High-Risk Myelofibrosis', 'source': 'Hematology Advisor', 'date': 'Sep 18, 2023', 'snippet': 'In September 2023, the US Food and Drug Administration (FDA) approved \nOjjaara (momelotinib; GlaxoSmithKline), a kinase inhibitor,...', 'thumbnail': 'https://serpapi.com/searches/6722e3d4acf7f8291ac533bd/images/934e093614527ab06f7d201555cdc98c4825778b81c2fb0db4508789281d69c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8874692916870117}","{'position': 3, 'link': 'https://www.targetedonc.com/view/momelotinib-improves-anemia-in-jak-inhibitor-naive-myelofibrosis', 'title': 'Momelotinib Improves Anemia in JAK Inhibitor-Naive Myelofibrosis', 'source': 'Targeted Oncology', 'date': 'May 9, 2024', 'snippet': 'Compared with ruxolitinib, momelotinib improved mild, moderate, and severe \nanemia in patients with myelofibrosis who were naive to JAK...', 'thumbnail': 'https://serpapi.com/searches/6722e3d4acf7f8291ac533bd/images/934e093614527ab00a82780ccaefabd08022c42176982a71357dce5cb34938b8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7391460537910461}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04782388,"{'position': 1, 'link': 'https://www.researchgate.net/publication/378467857_Pharmacokinetics_of_Staccato_alprazolam_in_healthy_adult_participants_in_two_phase_1_studies_An_open-label_smoker_study_and_a_randomized_placebo-controlled_ethnobridging_study', 'title': '(PDF) Pharmacokinetics of Staccato alprazolam in healthy adult participants in two phase 1 studies: An open‐label smoker study and a randomized, placebo‐controlled ethnobridging study', 'source': 'ResearchGate', 'date': 'Jun 26, 2024', 'snippet': 'PDF | Objective Staccato® alprazolam is a single‐use, drug–device \ncombination delivering alprazolam to the deep lung that is being \nevaluated...', 'thumbnail': 'https://serpapi.com/searches/6722e40f39e232ed6dec16b3/images/60858720fa8a9816a56f35234801599c489f1fd63564c9312431fb62dcb63439.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8950238227844238}",,,,,,,,,,['neutral'],neutral,1 NCT00537368,"{'position': 1, 'link': 'https://www.nature.com/articles/s42003-020-01441-y', 'title': 'Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy', 'source': 'Nature', 'date': 'Nov 27, 2020', 'snippet': 'Immunotherapies targeting the PD-1/PD-L1 axis are now a mainstay in the \nclinical management of multiple cancer types, however,...', 'thumbnail': 'https://serpapi.com/searches/6722e4585bb6a2400c71ddf9/images/fc730225a2db4334a0af2080ef9a2dfed477ae8d0191f57277a849fbe2ad5a78.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.832412600517273}",,,,,,,,,,['neutral'],neutral,1 NCT04751136,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/dmcn.15517', 'title': 'State‐of‐the‐art therapy for Down syndrome - Lorenzon - 2023 - Developmental Medicine & Child Neurology', 'source': 'Wiley Online Library', 'date': 'Jan 24, 2023', 'snippet': 'This review covers five key areas: (1) What has happened in the last 10 \nyears? (2) From symptomatic to disease-modifying therapy:...', 'thumbnail': 'https://serpapi.com/searches/6722e45dba11426bb27b36f4/images/7e8883b0f95e4f123ed2d26f45cbf688237ff19fda3e2eae04c34ef43c50bd3c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9450766444206238}",,,,,,,,,,['neutral'],neutral,1 NCT03781167,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/vyalev-severe-parkinsons-motor-symptoms-available-canada/', 'title': ""Vyalev, for severe Parkinson's motor symptoms, arrives in Canada"", 'source': ""Parkinson's News Today"", 'date': 'Feb 12, 2024', 'snippet': 'The continuous, infusion pump therapy is for advanced disease and severe \nfluctuations no longer controlled by oral levodopa/carbidopa.', 'thumbnail': 'https://serpapi.com/searches/6722e48e6a5dd373ed509849/images/0f83474cef5d4edf20c172323779c0addf8ec8c80d8cac960d7e43e700b4a19d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8271430730819702}",,,,,,,,,,['neutral'],neutral,1 NCT02301624,"{'position': 1, 'link': 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death of virus-infected tumor \ncells and this has been shown in preclinical models to enhance...', 'thumbnail': 'https://serpapi.com/searches/6722e5d848c42962967b42f2/images/6cefe4818eeb3150c56788e095fec51ab51dd464c2e586baa78c60ff45786ebd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6280909180641174}",,,,,,,,,,['neutral'],neutral,1 NCT04945772,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/nanoscope-therapeutics-announces-positive-topline-results-from-phase-2b-restore-trial-of-mco-010-for-the-treatment-of-retinitis-pigmentosa-301785351.html', 'title': 'Nanoscope Therapeutics Announces Positive Topline Results from Phase 2b RESTORE Trial of MCO-010 for the Treatment of Retinitis Pigmentosa', 'source': 'PR Newswire', 'date': 'Mar 30, 2023', 'snippet': 'Results showed vision function improvements after treatment with MCO-010 \nconsistent with previous studies as well as a favorable safety profile.', 'thumbnail': 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DALLAS, Oct. 21, 2024. DALLAS, Oct. 21, 2024 /PRNewswire/ -- \nNanoscope Therapeutics Inc., a late-stage clinical biotechnology...', 'thumbnail': 'https://serpapi.com/searches/6722e5de667ec536558ed5af/images/775b2e30d75ef756f7e4ebd60fe6aa4461f575c457bd21ec92b7b2158e7453aa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9169276356697083}","{'position': 6, 'link': 'https://www.cgtlive.com/view/ramos-platt-looking-forward-gene-therapy-growth', 'title': 'Leigh Ramos-Platt, MD, on Looking Forward to Gene Therapy’s Growth', 'source': 'CGTLive®', 'date': 'Jul 9, 2024', 'snippet': 'The clinical professor of neurology and pediatrics at Keck School of \nMedicine of USC also discussed current strategies with gene therapy...', 'thumbnail': 'https://serpapi.com/searches/6722e5de667ec536558ed5af/images/775b2e30d75ef75620e7cdb0b34e102ad8740876881209da3d373448188eb9fb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6632293462753296}","{'position': 7, 'link': 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""Fabry Disease Therapy Migalastat's Approval Under FDA Review"", 'source': 'Fabry Disease News', 'date': 'Jan 25, 2018', 'snippet': 'Read how Amicus Therapeutics has submitted a new drug application to the \nFDA for oral migalastat in Fabry disease in patients with amenable...', 'thumbnail': 'https://serpapi.com/searches/6722e92a2bab90dba32722e1/images/8292e8a91d2816133c306657705f0276db95f4c8ce1cf907ed21f98df2a8316f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8668466210365295}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01709864,"{'position': 1, 'link': 'https://copdnewstoday.com/news/new-copd-treament-option-seebri-neohaler-now-available-to-us-patients/', 'title': 'New COPD Treament Option, Seebri Neohaler, Now Available to U.S. Patients', 'source': 'COPD News Today', 'date': 'Oct 23, 2017', 'snippet': 'Seebri Neohaler, a long-term maintenance therapy for airflow obstruction in \npatients with chronic obstructive pulmonary disease (COPD), is now 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Since factor Xa plays a central role in \nthrombosis,...', 'thumbnail': 'https://serpapi.com/searches/6722ee8f24296aed45f173df/images/6ae901166944bbafe273efecf372dd022429066d65a1d8fbc72abfb0317a00a4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5768699645996094}",,,,,,,,,,['neutral'],neutral,1 NCT02725567,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/kalydeco-approved-eu-cf-children-young-1-month/', 'title': 'Kalydeco approved in EU for CF children as young as 1 month', 'source': 'Cystic Fibrosis News Today', 'date': 'Apr 29, 2024', 'snippet': 'The European Commission has approved Kalydeco (ivacaftor) for CF infants as \nyoung as a month with at least one CFTR gating mutation.', 'thumbnail': 'https://serpapi.com/searches/6722eec529e6fbf3605b31a1/images/cbc22cd2f87676629ef629bc3f8de1627bffe466ae372e63825fc18f78621ef7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8572079539299011}","{'position': 2, 'link': 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GBS vaccine', 'source': 'Pf Media', 'date': 'Apr 17, 2023', 'snippet': 'MinervaX has announced the first phase 1 clinical study in older adults of \nits novel vaccine for Group B Streptococcus.', 'thumbnail': 'https://serpapi.com/searches/6722eff5b6ed337ce072e99b/images/61ab751dcddf4f0509d8a2c81bed64ff78700a790d5b818661f7aa752c53a010.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8728817105293274}",,,,,,,,,,['neutral'],neutral,1 NCT03003676,"{'position': 1, 'link': 'https://melanomanewstoday.com/2017/05/18/first-patient-enrolled-in-oncos-102-keytruda-combo-trial-advanced-melanoma/', 'title': 'First Patient Enrolled in ONCOS-102, Keytruda Combo Trial for Advanced Melanoma', 'source': 'Melanoma News Today', 'date': 'May 18, 2017', 'snippet': ""The first patient has been enrolled in Targovax's pilot clinical trial for \nadvanced or unresectable melanoma patients whose cancer..."", 'thumbnail': 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approved NexoBrid \n(anacaulase-bcdb) for eschar removal in adults with deep partial thickness \nand/or full thickness...', 'thumbnail': 'https://serpapi.com/searches/6722f09e81262a594b8d1c7d/images/1b320fe45a273d42df69f1c1829156b4f93784aa197b766a0ee25b68110b89bf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6989240646362305}","{'position': 2, 'link': 'https://www.empr.com/home/news/nexobrid-now-available-for-treatment-of-severe-thermal-burns/', 'title': 'NexoBrid Now Available for Treatment of Severe Thermal Burns', 'source': 'Medical Professionals Reference', 'date': 'Sep 21, 2023', 'snippet': 'NexoBrid (anacaulase-bcdb) is now available for eschar removal in adults \nwith deep partial thickness and/or full thickness thermal burns.', 'thumbnail': 'https://serpapi.com/searches/6722f09e81262a594b8d1c7d/images/1b320fe45a273d425c39c15a4652df5fe95de85dc1ffd0f830514475bb0e17d3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8987787961959839}",,,,,,,,,"['neutral', 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'The New England Journal of Medicine', 'date': 'Oct 27, 2021', 'snippet': 'Interleukin-23 has been implicated in airway inflammation that is mediated \nby type 2 and type 17 cytokines. Whether targeting interleukin-23...', 'thumbnail': 'https://serpapi.com/searches/6722f0db9fd309c7d4ccaaba/images/1d804c6adc9f09b668db81a9ba8a285812acb369a6b55c3569237d0f134a3238.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6266525387763977}",,,,,,,,,,['neutral'],neutral,1 NCT05660109,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20241015961357/en/Topas-Therapeutics-Announces-Positive-Topline-Results-from-Phase-2a-Trial-Evaluating-TPM502-in-Patients-with-Celiac-Disease', 'title': 'Topas Therapeutics Announces Positive Topline Results from Phase 2a Trial Evaluating TPM502 in Patients with Celiac Disease', 'source': 'Business Wire', 'date': '2 weeks ago', 'snippet': 'TPM502 demonstrated a good safety profile in celiac disease patients; The \ndata indicates proof of concept that TPM502 induced targeted,...', 'thumbnail': 'https://serpapi.com/searches/6722f1372fab620db40993b2/images/f00f7608417477a250290c4d3effaa58747eed21c047e7e61444b31910f7d332.png', 'sentiment': 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'Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor', 'source': 'Nature', 'date': 'May 7, 2021', 'snippet': 'The discovery of robust antidepressant actions exerted by the \nN-methyl-D-aspartate receptor (NMDAR) antagonist (R,S)-ketamine has been \na...', 'thumbnail': 'https://serpapi.com/searches/6722f1c115c7405910f6573c/images/59e8689da258fc2d995c1ac0257785b5d64b9bbbf8fe86d198892d8ecb428330.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8802525401115417}",,,,,,,,,,['neutral'],neutral,1 NCT02744339,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIR.0000000000001079', 'title': 'Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action: A Science Advisory From the American Heart Association', 'source': 'American Heart Association Journals', 'date': 'Jul 11, 2022', 'snippet': 'This science advisory focuses on the need to 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supplemental New \nDrug Application (sNDA) for Vuity (pilocarpine hydrochloride...', 'thumbnail': 'https://serpapi.com/searches/6722f2a4ba13f2d17b1d8bd3/images/7f09df38fcac535543cd413b54f72326bad3bd2fa5b4e4de4e929b0af0029ce4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8455018997192383}",,,,,,,,,,['neutral'],neutral,1 NCT03693781,"{'position': 1, 'link': 'https://alsnewstoday.com/news/als-mnd-2023-gout-med-colchicine-als-progression/', 'title': 'ALS/MND 2023: Gout med colchicine did not slow ALS progression', 'source': 'ALS News Today', 'date': 'Dec 8, 2023', 'snippet': 'The gout medication colchicine failed to significantly slow ALS progression \nin a small clinical trial conducted in Europe.', 'thumbnail': 'https://serpapi.com/searches/6722f2c616779391e19a8918/images/0abf2a848997d5f1f0e5572e45df1cb245618585b9c6455647836b5c9f778f93.png', 'sentiment': 'negative', 'sentiment_prob': 0.7509196400642395}",,,,,,,,,,['negative'],negative,0 NCT00325195,"{'position': 1, 'link': 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'snippet': 'Immunotherapy has revolutionized treatment of cancer during the last \ndecades. 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'date': 'Sep 5, 2023', 'snippet': 'The 9-valent human papillomavirus (9vHPV) vaccine Phase III immunogenicity \nstudy in 9- to 15-year-old boys and girls was extended to assess \nimmunogenicity and...', 'thumbnail': 'https://serpapi.com/searches/6722f3a6fcd69e83509dbd29/images/6215f85a5bbd3536f2f16db24aed83b2acecd2125f221034e11e66450bc12ca6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8899199366569519}",,,,,,,,,,['neutral'],neutral,1 NCT03347344,"{'position': 1, 'link': 'https://www.neurologyadvisor.com/news/spinocerebellar-ataxia-type-2-treatment-riluzole-efficacious/', 'title': 'Spinocerebellar Ataxia Type 2 Treatment: Is Riluzole Effective?', 'source': 'Neurology Advisor', 'date': 'Feb 8, 2022', 'snippet': 'A randomized trial found that riluzole did not improve clinical or \nradiological outcomes among patients with spinocerebellar ataxia type 2 \n(SCA2).', 'thumbnail': 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'title': 'Seizure treatment bexicaserin gets FDA breakthrough therapy nod', 'source': 'Dravet Syndrome News', 'date': 'Jul 9, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has granted breakthrough therapy \ndesignation to Longboard Pharmaceuticals' bexicaserin to treat seizures."", 'thumbnail': 'https://serpapi.com/searches/6722f41da54d7e5b1f72f4e0/images/6030e970123a4ede1ac251b094bcbcbf6946a2723b3dee8257aced8bdb32176e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5533022284507751}","{'position': 3, 'link': 'https://dravetsyndromenews.com/news/pacific-study-lp352-dravet-other-epilepsies-hits-enrollment-goal/', 'title': 'PACIFIC study of LP352 for epilepsies hits enrollment target', 'source': 'Dravet Syndrome News', 'date': 'Sep 5, 2023', 'snippet': 'Longboard Pharmaceuticals has finished enrolling patients in PACIFIC, its \nPhase 1b/2a clinical study of LP352, an investigational oral...', 'thumbnail': 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information \nbefore deciding whether to approve the apomorphine infusion pump SPN-830 \nfor the...', 'thumbnail': 'https://serpapi.com/searches/6722f4380197ddc6e9729c65/images/c81fc69d06b756587be644acb5b0d4734a76a6fe6a227f29819a4140c95078eb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9497389197349548}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/fda-sets-2024-decision-date-apomorphine-pump-spn-830-parkinsons/', 'title': 'FDA sets date in 2024 for decision on SPN-830 apomorphine pump', 'source': ""Parkinson's News Today"", 'date': 'Nov 3, 2023', 'snippet': ""The U.S. Food and Drug Administration (FDA) has accepted Supernus \nPharmaceuticals' new application seeking approval of its apomorphine..."", 'thumbnail': 'https://serpapi.com/searches/6722f4380197ddc6e9729c65/images/c81fc69d06b75658ba1e791c93075d2cb1ee1cdb6052841deb0713ffddbe8a0b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8884477615356445}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02386839,"{'position': 1, 'link': 'https://www.nature.com/articles/s41390-018-0228-0', 'title': 'Preventing bronchopulmonary dysplasia: new tools for an old challenge', 'source': 'Nature', 'date': 'Nov 21, 2018', 'snippet': 'Bronchopulmonary dysplasia (BPD) is the most prevalent chronic lung disease \nin infants and presents as a consequence of preterm birth.', 'thumbnail': 'https://serpapi.com/searches/6722f43c2bab90dbe8e60296/images/61b4790f14f2ad06a452ac34cc7d8becdefb8c3e8fd16d8d5bc80fe95d9da77f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6512972116470337}",,,,,,,,,,['neutral'],neutral,1 NCT02437318,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1813904', 'title': 'Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'May 15, 2019', 'snippet': 'PIK3CA mutations occur in approximately 40% of patients with hormone \nreceptor (HR)–positive, human epidermal growth factor receptor 2...', 'thumbnail': 'https://serpapi.com/searches/6722f46b671f3fe9cb2306da/images/68a4a81ed82235def73bc8e57d5e402d89784b24bb62dd2dd91ed68ee05441c3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6224144101142883}","{'position': 2, 'link': 'https://breastcancer-news.com/2020/08/24/eu-approves-piqray-faslodex-combo-hr-positive-her2-negative-breast-cancer-pik3ca-mutation/', 'title': 'EU Approves Piqray-Faslodex Combo for Certain Advanced Breast Cancer With PIK3CA Mutation', 'source': 'Breast Cancer News', 'date': 'Aug 24, 2020', 'snippet': 'The EU has approved Piqray with Faslodex as a treatment for HR+/HER2- \nadvanced or metastatic breast cancer that harbors a PIK3CA mutation.', 'thumbnail': 'https://serpapi.com/searches/6722f46b671f3fe9cb2306da/images/68a4a81ed82235deca621edc8bd65669b252721032a99025280f2908cbd9bb54.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8750541806221008}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02598557,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/breast-cancer-exemestane-given-3-times-week-is-noninferior-daily-dosing/', 'title': 'Exemestane Given 3 Times a Week Is Noninferior to Daily Dosing in Breast Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Apr 4, 2023', 'snippet': 'A 3-times-weekly dose of exemestane appears noninferior to standard daily \ndosing in estrogen receptor-positive breast cancer patients, according to \nresearch.', 'thumbnail': 'https://serpapi.com/searches/6722f4b2bcd6529d39ba6535/images/6c01e0f93d816c5ff991c2129d3e9e03e9ec0dc2ecfdd4e4797d9c7af315254b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5581798553466797}",,,,,,,,,,['neutral'],neutral,1 NCT02450552,"{'position': 1, 'link': 'https://www.als.org/blog/motor-neuron-excitability-reduced-people-als-following-ezogabine-treatment', 'title': 'Motor Neuron Excitability is Reduced in People with ALS Following Ezogabine Treatment', 'source': 'The ALS Association', 'date': 'Dec 24, 2020', 'snippet': 'Dr. Brian Wainger from the Massachusetts General Hospital (MGH) presented \ninitial top-level results from a recently completed phase II clinical trial \nof...', 'thumbnail': 'https://serpapi.com/searches/6722f4d9fc183dcd64140629/images/cdc891ecc00c1acbf18a396cb5e82b78906bd46ba791d98bdb1e82c375d17ac0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7142907977104187}",,,,,,,,,,['neutral'],neutral,1 NCT01776424,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.046048', 'title': 'The COMPASS Trial:', 'source': 'American Heart Association Journals', 'date': 'May 21, 2020', 'snippet': 'Rivaroxaban 2.5 mg twice daily plus acetylsalicylic acid (aspirin; ASA) 100 \nmg reduced the risk of cardiovascular events as compared with ASA \nmonotherapy in...', 'thumbnail': 'https://serpapi.com/searches/6722f4eee9245621f556e18d/images/6c330b78031be42b448a7355328d52b53ded8afed1e69ddb944e01e8275db9f3.png', 'sentiment': 'neutral', 'sentiment_prob': 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'Transcriptional deregulation has emerged as a hallmark of several cancer \ntypes. In metastatic castration-resistant prostate cancer,...', 'thumbnail': 'https://serpapi.com/searches/6722f54a81262a594b8d21a2/images/a8c69fda1ec041758af73961d6db2e2c9a580660daccfca48be53afaf69672b4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.586356520652771}",,,,,,,,,,['neutral'],neutral,1 NCT02267603,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1603702', 'title': 'PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma', 'source': 'The New England Journal of Medicine', 'date': 'Mar 11, 2017', 'snippet': 'In this study, first-line therapy with pembrolizumab in patients with \nadvanced Merkel-cell carcinoma was associated with an objective response \nrate of 56%.', 'thumbnail': 'https://serpapi.com/searches/6722f57e59f9112fb14a0a95/images/934e6c6ae82a1b13428fe5d180a2c77005de75aedae5962abd012044a455fdf0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.861939549446106}","{'position': 2, 'link': 'https://immuno-oncologynews.com/2019/02/22/keytruda-better-than-chemotherapy-untreated-advanced-merkel-cell/', 'title': 'Study: Keytruda Better Than Chemotherapy for Untreated Merkel Cell', 'source': 'Immuno-Oncology News', 'date': 'Feb 22, 2019', 'snippet': 'Patients with an aggressive kind of skin cancer called Merkel cell \ncarcinoma appear to have better responses and live longer when given the \nPD-1 inhibitor...', 'thumbnail': 'https://serpapi.com/searches/6722f57e59f9112fb14a0a95/images/934e6c6ae82a1b138db736a6d8802612e105d6d9a0f82fa7de3fa998e69c3f58.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5485749244689941}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03507790,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/ct1812-slows-cognitive-decline-proof-concept-alzheimers-trial/', 'title': 'CT1812 slows cognitive decline in proof-of-concept clinical trial', 'source': ""Alzheimer's News Today"", 'date': 'Aug 22, 2024', 'snippet': ""CT1812 was shown to slow the decline of cognitive function in adults with \nAlzheimer's disease in a proof-of-concept clinical trial."", 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dc1986c291e2add39afa15e9aa687ac17c91b6e68985e36f59.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7613821625709534}","{'position': 2, 'link': 'https://www.neurologylive.com/view/neurovoices-anthony-caggiano-therapeutic-progress-alzheimer-agent-ct1812', 'title': 'NeuroVoices: Anthony Caggiano, MD, PhD, on Therapeutic Progress of Alzheimer Agent CT1812', 'source': 'Neurology live', 'date': 'Aug 21, 2024', 'snippet': 'The chief medical officer and head of Research & Development at Cognition \nTherapeutics discussed data from the phase 2 proof-of-concept...', 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dc123eeaec0b18e0816e2ef9b5bcaa105b7ec61f3a5ef4a608.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9362901449203491}","{'position': 3, 'link': 'https://www.morningstar.com/news/globe-newswire/9263884/cognition-therapeutics-announces-results-of-pre-specified-analysis-of-shine-study-data-presented-at-ctad', 'title': 'Cognition Therapeutics Announces Results of Pre-specified Analysis of SHINE Study Data Presented at CTAD', 'source': 'Morningstar', 'date': '1 day ago', 'snippet': 'Results show CT1812 dramatically slowed cognitive decline in patients with \nlower levels of plasma p-tau217, an important biomarker of...', 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dcdf45b94745b430f5c34d69434dd7db406d983703705a5054.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8459738492965698}","{'position': 4, 'link': 'https://finance.yahoo.com/news/cognition-therapeutics-proof-concept-phase-110000080.html', 'title': 'Cognition Therapeutics’ Proof-of-Concept Phase 2 SHINE Trial Demonstrates Consistent Improvement in Cognitive Outcomes with Once-Daily Oral CT1812 in Mild-to-Moderate Alzheimer’s Patients', 'source': 'Yahoo Finance', 'date': 'Jul 29, 2024', 'snippet': 'The SHINE trial showed that after 182 days of treatment, CT1812 \ndemonstrated evidence of clinical improvements on cognition coupled with a \nfavorable safety and...', 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dcf977bfb6d07c0172448ad6caed0c4b05fb1376d5cf3aac65.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5829297304153442}","{'position': 5, 'link': 'https://www.genengnews.com/topics/drug-discovery/as-biopharma-giants-reshape-the-field-cognition-therapeutics-sees-a-place-for-its-alzheimers-drug/', 'title': 'As Biopharma Giants Reshape the Field, Cognition Therapeutics Sees a Place for Its Alzheimer’s Drug', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Oct 23, 2023', 'snippet': ""Cognition Therapeutics' CT1812 is a once-daily, oral, brain penetrant \nsmall-molecule antagonist of the sigma-2 receptor (S2R) that has completed \none Phase II..."", 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dceb88639302fe3a8bf5aa8b7f0c51663dd3e2e1ef9ae5d81b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8050349354743958}","{'position': 6, 'link': 'https://alzheimersnewstoday.com/ct1812/', 'title': 'Elayta (CT1812)', 'source': ""Alzheimer's News Today"", 'date': 'Apr 7, 2018', 'snippet': ""CT1812 is an oral medication being developed by Cognition Therapeutics, now \nin clinical testing, to possibly treat mild-to-moderate Alzheimer's disease \nby..."", 'thumbnail': 'https://serpapi.com/searches/6722f5c19819f339e37905e6/images/85f9911ffccb61dc1eb62a57e71905b90dd953e63db1677e78bf968210f450e6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8871570825576782}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03804996,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/hon.3164_434', 'title': 'First-in-Human (FIH) Study of the Fully-Human 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'Phase I Escalation and Expansion Study of Bemarituzumab (FPA144) in Patients With Advanced Solid Tumors and FGFR2b-Selected Gastroesophageal Adenocarcinoma', 'source': 'ASCO Publications', 'date': 'Mar 13, 2020', 'snippet': 'PURPOSETo evaluate the safety, pharmacokinetics, and preliminary activity \nof bemarituzumab in patients with FGFR2b-overexpressing gastric...', 'thumbnail': 'https://serpapi.com/searches/6722f9b5a32436a16214c69c/images/7901d8a007e83a48bdc49bb7649c91d24b43829f46bf6e75293d91b36dd0dd29.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8843021988868713}",,,,,,,,,,['neutral'],neutral,1 NCT04436497,"{'position': 1, 'link': 'https://alsnewstoday.com/news/ucb-stops-zilucoplan-arm-early-healey-trial-als-lack-of-efficacy/', 'title': 'Zilucoplan Arm in HEALEY Trial for ALS Stopped Early for Lack of Benefit', 'source': 'ALS News Today', 'date': 'Mar 7, 2022', 'snippet': ""The Phase 2/3 clinical trial testing UCB's investigational therapy \nzilucoplan for amyotrophic lateral 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'https://lungdiseasenews.com/2018/01/12/european-union-oks-orkambi-children-cf/', 'title': 'European Union OKs Orkambi Use for Children 6-11 Years Old With CF', 'source': 'Lung Disease News', 'date': 'Jan 12, 2018', 'snippet': 'EU grants extension of marketing authorization for Orkambi to include \nchildren aged 6 to 11 who have CF and two copies of the F508del...', 'thumbnail': 'https://serpapi.com/searches/6722fa19d771bd6b2e5e596d/images/31b853aceafdf51dbbfaf40207a8e0abcaf3012a1daa2ecfa15cf7837df994d6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7960894703865051}",,,,,,,,,,['neutral'],neutral,1 NCT04751539,"{'position': 1, 'link': 'https://www.abc4.com/business/press-releases/cision/20241028CN42084/kind-presents-positive-results-of-and017-to-treat-anemia-associated-with-chronic-kidney-disease-in-two-phase-ii-and-two-phase-i', 'title': 'KIND Presents Positive Results of AND017 to Treat Anemia Associated with Chronic Kidney Disease in Two Phase II and Two Phase I', 'source': 'ABC4 Utah', 'date': '2 days ago', 'snippet': 'Clinical Trials at American Society of Nephrology (ASN) – Kidney Week 2024. \nSAN FRANCISCO, Oct. 28, 2024 /PRNewswire/ -- Kind Pharmaceutical...', 'thumbnail': 'https://serpapi.com/searches/6722f87d717bff91dacb3ae2/images/c2c8d2e4e9bd4d530a87957ec4ec61f7cc7915b8ca2787b6f3cdb5bd574bcb20.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.606677770614624}",,,,,,,,,,['neutral'],neutral,1 NCT04411628,"{'position': 1, 'link': 'https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03345-3', 'title': 'Relationship between gene expression patterns from nasopharyngeal swabs and serum biomarkers in patients hospitalized with COVID-19, following treatment with the neutralizing monoclonal antibody bamlanivimab', 'source': 'Journal of Translational Medicine', 'date': 'Mar 18, 2022', 'snippet': 'This safety-focused study aims to monitor and characterize the immune \nresponse to SARS-CoV-2 infection via analysis of peripheral blood 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'source': 'ALS News Today', 'date': 'Oct 11, 2023', 'snippet': ""PrimeC, NeuroSense Therapeutics' investigational, fixed-dose combination \ntherapy for amyotrophic lateral sclerosis (ALS), significantly boosted the \nsurvival of..."", 'thumbnail': 'https://serpapi.com/searches/6722f97bb691a72d6399fb8a/images/ab876361d100adff72af829d6f23ba0bd873166422f975d15ef8b1c29ee50484.png', 'sentiment': 'positive', 'sentiment_prob': 0.6819302439689636}","{'position': 4, 'link': 'https://alsnewstoday.com/news/primec-potential-als-therapy-earns-patents-in-europe-japan-israel/', 'title': 'PrimeC, potential ALS therapy, earns patents in Europe, Japan, Israel', 'source': 'ALS News Today', 'date': 'Oct 2, 2023', 'snippet': 'NeuroSense received patents covering the use of PrimeC in Europe, Japan, \nand Israel; topline data from the Phase 2 trial are expected soon.', 'thumbnail': 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Information may be found in the online version of \nthis article. 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'sentiment_prob': 0.795064389705658}","{'position': 5, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/12/20/neurofilament-light-chain-studied-ms-prognosis-biomarker/', 'title': 'Neurofilament Light Chain Studied as MS Prognosis Biomarker |...', 'source': 'Multiple Sclerosis News Today', 'date': 'Dec 20, 2022', 'snippet': 'A study showed neurofilament light chain tends to be associated with \nmultiple sclerosis progression and is lowered with Gilenya treatment.', 'thumbnail': 'https://serpapi.com/searches/6722fc64cc4879ca15c16abd/images/6aaefe43ed6b51e59e09f5895b6bdd97e75763a6401b173fa862e1a44f7ecc1b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8330132365226746}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04435431,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/phase-3-trial-mesdopeta-parkinsons-dyskinesia-planned/', 'title': 'Irlab moving on Phase 3 trial of mesdopetam to treat dyskinesia', 'source': ""Parkinson's 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'source': 'Pulmonary Fibrosis News', 'date': '٠٣\u200f/٠٥\u200f/٢٠٢٢', 'snippet': 'Galecto has reached its enrollment target for its Phase 2b clinical trial, \nGALACTIC-1, testing GB0139 as a once-daily inhaled therapy for...', 'thumbnail': 'https://serpapi.com/searches/6722fced175de61401c726df/images/683b46b5d1a2f9d4094abb086135499bf32000f5ab1e150e9a55355b54fb1720.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5557882189750671}",,,,,,,,,,['neutral'],neutral,1 NCT04233814,"{'position': 1, 'link': 'https://pulmonaryfibrosisnews.com/news/inhaled-ipf-therapy-lti-03-well-tolerated-healthy-volunteers-trial/', 'title': 'Inhaled IPF Therapy LTI-03 Well-tolerated in Healthy Volunteers in Trial', 'source': 'Pulmonary Fibrosis News', 'date': 'Mar 23, 2022', 'snippet': ""Lung Therapeutics' LTI-03 candidate for idiopathic pulmonary fibrosis was \nsafe and well-tolerated in healthy people in a Phase 1a trial."", 'thumbnail': 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far been published in a peer-reviewed journal.', 'thumbnail': 'https://serpapi.com/searches/6722fe3da5aae9d2bd030cd8/images/af01dfeb73cc3bfe0e2cdbffbca11836bdc5bde4349b710e543512d966f84b90.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.865156352519989}",,,,,,,,,,['neutral'],neutral,1 NCT03298672,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/fosgonimeton-shows-safety-phase-1-study-phase-3-trial-enrolling-us/', 'title': 'Fosgonimeton Shows Safety in Early Trial, Phase 3 Study Enrolling in US', 'source': ""Alzheimer's News Today"", 'date': 'Feb 28, 2022', 'snippet': ""Fosgonimeton, an experimental therapy Athira Pharma is developing to treat \nAlzheimer's disease, was well-tolerated overall in a Phase 1 clinical trial."", 'thumbnail': 'https://serpapi.com/searches/6722fe4607c7be84e55fc004/images/dbb87506f336120ff7429c4363d84f038d450393d108f10ec211e14938f51a0b.png', 'sentiment': 'positive', 'sentiment_prob': 0.7711381912231445}",,,,,,,,,,['positive'],positive,1 NCT02669121,"{'position': 1, 'link': 'https://www.pharmaceutical-technology.com/news/hillevax-slashes-workforce-by-40-after-norovirus-vaccine-trial-failure/', 'title': 'HilleVax slashes workforce by 40% after norovirus vaccine trial failure', 'source': 'Pharmaceutical Technology', 'date': 'Aug 1, 2024', 'snippet': ""HilleVax's norovirus vaccine HIL-214 failed to meet key endpoints in its \nPhase IIb trial in infants prompting the company to let go of 41..."", 'thumbnail': 'https://serpapi.com/searches/6722fe5508abe49569de87d6/images/7f5e89132441f981c0af359c3f9feb607c02e53ac1334e4a171917b215885e0b.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8878931999206543}",,,,,,,,,,['negative'],negative,0 NCT01620528,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1700089', 'title': 'Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist', 'source': 'The New England Journal of Medicine', 'date': 'Nov 10, 2017', 'snippet': 'We performed two 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For patients who responded to their first treatment,...', 'thumbnail': 'https://serpapi.com/searches/6722feb171b0e875fe4d5e8b/images/1eeb5da733dcbd6abd88c0276333952f9dcd5105a0834f7736e42f95d21cae48.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5939822196960449}","{'position': 2, 'link': 'https://www.nature.com/articles/s41386-023-01751-9', 'title': 'Efficacy and safety of zuranolone co-initiated with an antidepressant in adults with major depressive disorder: results from the phase 3 CORAL study', 'source': 'Nature', 'date': 'Oct 24, 2023', 'snippet': 'These results demonstrate that zuranolone+ADT provided more rapid \nimprovement in depressive symptoms compared with placebo+ADT in patients \nwith MDD.', 'thumbnail': 'https://serpapi.com/searches/6722feb171b0e875fe4d5e8b/images/1eeb5da733dcbd6aa6300e2c7e87d1d7c09d5791edd135f2d856d0a8d707d4f0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5984835028648376}","{'position': 3, 'link': 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2020', 'snippet': 'An ALKS 4230-Keytruda combo was able to halt disease progression and reduce \ntumor size in women with advanced ovarian cancer,...', 'thumbnail': 'https://serpapi.com/searches/6722fef818787d0b9597e56f/images/fb44b969b66857d3698a83862bf795b520f42451eada2b04d8a0fc05ee5c0c70.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7647801637649536}",,,,,,,,,,['neutral'],neutral,1 NCT02877927,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30275-0/abstract', 'title': 'Once-daily oral omadacycline versus twice-daily oral linezolid for acute bacterial skin and skin structure infections (OASIS-2): a phase 3, double-blind, multicentre, randomised, controlled, non-inferiority trial', 'source': 'The Lancet', 'date': 'Aug 29, 2019', 'snippet': 'We aimed to compare the efficacy and safety of once-daily oral \nomadacycline, an aminomethylcycline antibiotic, versus twice-daily oral \nlinezolid for treatment...', 'thumbnail': 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'snippet': 'By Myles Starr The recent announcement of phase 3 clinical trial results \ndemonstrating that semaglutide 2.4 mg (Wegovy, Novo Nordisk)...', 'thumbnail': 'https://serpapi.com/searches/67230094f79a012c6dcad41a/images/c5853a4b3ced80f80ec72374354bcdb84817f465eb536fb80346855b43df9bd1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5210405588150024}",,,,,,,,,,['neutral'],neutral,1 NCT03579628,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-01028-8', 'title': 'A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics and pharmacodynamics of AsiDNA, a first-in-class DNA repair inhibitor, administered intravenously in patients with advanced solid tumours', 'source': 'Nature', 'date': 'Aug 25, 2020', 'snippet': 'AsiDNA, a first-in-class oligonucleotide-mimicking double-stranded DNA \nbreaks, acts as a decoy agonist to DNA damage response in tumour...', 'thumbnail': 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'https://www.nejm.org/doi/full/10.1056/NEJMoa1602773', 'title': 'Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease', 'source': 'The New England Journal of Medicine', 'date': 'Nov 17, 2016', 'snippet': 'Ustekinumab, a monoclonal antibody to the p40 subunit of interleukin-12 and \ninterleukin-23, was evaluated as an intravenous induction therapy in two...', 'thumbnail': 'https://serpapi.com/searches/6722ff5d8db376c3934fc90d/images/307b8ed5a897cdba09706c1a000b0dae31a04eb982e34ad12f0b27f50c065a72.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9213168025016785}",,,,,,,,,,['neutral'],neutral,1 NCT01242488,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Olokizumzab', 'title': 'Olokizumab', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': ""Crohn's Disease, A Phase II Study to Assess the Efficacy and Safety of \nOlokizumab in Patients With Crohn's Disease, Phase 2, CD0001"", 'thumbnail': 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'https://www.clinicaltrialsarena.com/news/cybin-starts-final-cohort-dosing-in-psychedelic-mdd-treatment-trial/', 'title': 'Cybin starts final cohort dosing in psychedelic MDD treatment trial', 'source': 'Clinical Trials Arena', 'date': 'Aug 2, 2023', 'snippet': 'Cybin is closer to demonstrating results across all six cohorts from its \nPhase II trial investigating CYB003 in MDD.', 'thumbnail': 'https://serpapi.com/searches/6722ffec3c957520b177f0f8/images/ced8252ccb47bc540d57558ba57f43c0046a29dff376c148590fce958bba6cdf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.597998857498169}","{'position': 2, 'link': 'https://www.drugdiscoverytrends.com/the-future-of-mdd-treatment-a-comparative-table-highlighting-the-emergence-of-fast-acting-therapies/', 'title': 'MDD treatment landscape snapshot, including fast-acting options', 'source': 'www.drugdiscoverytrends.com', 'date': 'Nov 9, 2023', 'snippet': 'The treatment landscape for major depressive disorder (MDD) continues to \ndiversify, and in the coming years, psychedelic options may be available.', 'thumbnail': 'https://serpapi.com/searches/6722ffec3c957520b177f0f8/images/ced8252ccb47bc5466adc9cc0a1433364dfd9ba3c76f3f7bf25b4b48fe1f25ea.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7957701086997986}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02119468,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/relapsed-multiple-myeloma-patients-refractory-revlimid-benefit-ninlaro-pomalyst-dexamethasone-combo-trial-suggests/', 'title': 'Myeloma Patients Refractory to Revlimid May Benefit from Ninlaro, Pomalyst, Dexamethasone Combo', 'source': 'Myeloma Research News', 'date': 'Mar 19, 2018', 'snippet': 'Read about the results of a Phase 1/2 clinical trial showing that a triple \ncombo with Ninlaro, Pomalyst, and dexamethasone may help relapsed...', 'thumbnail': 'https://serpapi.com/searches/6722fffdd72128a2208b5b24/images/f251a879a7b3c49603ff490246b9de8c995505f03a14bf6b35692b792069b526.jpeg', 'sentiment': 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2014', 'snippet': 'Oritavancin is a lipoglycopeptide with bactericidal activity against \ngram-positive bacteria. 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US Food and Drug Administration (FDA) has cleared Astria Therapeutics \nto move STAR-0215, its experimental treatment for preventing swelling \nattacks in...', 'thumbnail': 'https://serpapi.com/searches/6723022ebb55ffdd70c765f4/images/442c135c5e5c4d03bc2c447a5b3618ad2f106043ea1a525fe2dabbc01a845698.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8257156014442444}",,,,,,,,,,['neutral'],neutral,1 NCT00938275,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-55923-8', 'title': 'Emerging roles of SIRT1 activator, SRT2104, in disease treatment', 'source': 'Nature', 'date': 'Mar 6, 2024', 'snippet': 'Silent information regulator 1 (SIRT1) is a NAD+-dependent class III \ndeacetylase that plays important roles in the pathogenesis of numerous...', 'thumbnail': 'https://serpapi.com/searches/67230237544c49553073b9bd/images/fa5f6db99f3cfcf5a3f37d438c7a00b98a8c19a2763a4b49819b6974a121faa6.png', 'sentiment': 'neutral', 'sentiment_prob': 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prospective, open-label, phase 2, randomised controlled trial', 'source': 'The Lancet', 'date': 'Mar 16, 2021', 'snippet': 'Current tuberculosis treatments leave patients with clinically significant \nlung injury and increased all-cause mortality post-cure.', 'thumbnail': 'https://serpapi.com/searches/672302b8c76a2266cd4d47b4/images/7dae0200bd2bc1ee7cb0f86d25bcafa381fa9f37ee03c4253e56a98b28e6d3be.png', 'sentiment': 'negative', 'sentiment_prob': 0.586892306804657}",,,,,,,,,,['negative'],negative,0 NCT04022473,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2020/05/04/fda-approves-bafiertam-banner-life-science-tecfidera-bioequivalent-relapsing-ms/', 'title': 'FDA Approves Bafiertam, Tecfidera Bioequivalent, for Relapsing MS', 'source': 'Multiple Sclerosis News Today', 'date': 'May 5, 2020', 'snippet': ""The US Food and Drug Administration (FDA) has given final approval to \nBanner Life Sciences' Bafiertam (monomethyl fumarate), a bioequivalent \nalternative to..."", 'thumbnail': 'https://serpapi.com/searches/672302fd81262a58f42c155a/images/039d296a082973ca823d84201c9f799a61c3a140d0abda4d61d4902609d3e85f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8079429864883423}",,,,,,,,,,['neutral'],neutral,1 NCT03568136,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-42595-z', 'title': 'Inhibition of IL-17 ameliorates keratinocyte-borne cytokine responses in an in vitro model for house-dust-mite triggered atopic dermatitis', 'source': 'Nature', 'date': 'Oct 3, 2023', 'snippet': 'This study aimed to investigate the potential of allergen-induced, \nimmune-cell derived IL-17 on the induction of inflammatory processes in \nkeratinocytes.', 'thumbnail': 'https://serpapi.com/searches/6723031b66d9954175f0df8d/images/16f7e6573faaba6663910202cafc70be16b0e1f28ceab88d4e8c7e8a2a92292a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8545948266983032}",,,,,,,,,,['neutral'],neutral,1 NCT04029116,"{'position': 1, 'link': 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suggests that urinalysis showing \npersistent blood in the urine (hematuria) can help identify...', 'thumbnail': 'https://serpapi.com/searches/6723039bb5ecbb095a174535/images/d80928584523f66d3dd269d5e3797a43f189cfd60e862be1a3695e6c08f42770.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9162073135375977}",,,,,,,,,,['neutral'],neutral,1 NCT01170663,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70420-6/abstract', 'title': 'Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial', 'source': 'The Lancet', 'date': 'Sep 17, 2014', 'snippet': 'We assessed whether ramucirumab, a monoclonal antibody VEGFR-2 antagonist, \nin combination with paclitaxel would increase overall survival in \npatients...', 'thumbnail': 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'https://www.endocrinologyadvisor.com/news/vaginal-progesterone-during-pregnancy/', 'title': 'Vaginal Progesterone During Pregnancy Could Benefit Neurodevelopment in CHD', 'source': 'Endocrinology Advisor', 'date': 'Jun 18, 2024', 'snippet': 'Vaginal progesterone during pregnancy showed some neurodevelopmental \nbenefits among female infants with congenital heart defects.', 'thumbnail': 'https://serpapi.com/searches/672303dc4e9efcf6a8efae8d/images/e5ba7b6130bcc212052ad80e94f586f48536e14c5dc0149dce28783b9b3d8f9e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8359719514846802}",,,,,,,,,,['neutral'],neutral,1 NCT04915729,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/full/10.1161/SVIN.124.001363', 'title': 'Tenecteplase Versus Alteplase in Acute Ischemic Stroke in Chinese Patients: Protocol for the ORIGINAL Study', 'source': 'American Heart Association Journals', 'date': 'May 7, 2024', 'snippet': 'BackgroundTenecteplase, a bioengineered variant of alteplase, is a new \nalternative thrombolytic agent. The ORIGINAL study aims to evaluate...', 'thumbnail': 'https://serpapi.com/searches/672303de483e5b863e715ede/images/b426d54b1a6d13a064b22bbcaf260e09d5b150c2b75125407990d3257a46d785.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9223576188087463}",,,,,,,,,,['neutral'],neutral,1 NCT03219268,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02593-0', 'title': 'The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial', 'source': 'Nature', 'date': 'Oct 19, 2023', 'snippet': 'Tebotelimab, a bispecific PD-1×LAG-3 DART molecule that blocks both PD-1 \nand LAG-3, was investigated for clinical safety and activity in a...', 'thumbnail': 'https://serpapi.com/searches/672303e2f3622a724e9c146c/images/277f94a83f3764ee2cf6cecd5865fd1d31860fbcddc22820366fa19d4b83d1b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9052724838256836}",,,,,,,,,,['neutral'],neutral,1 NCT01826201,"{'position': 1, 'link': 'https://lymphomanewstoday.com/2019/08/30/trial-of-cutaneous-t-cell-lymphoma-therapy-wp1220-fully-enrolled/', 'title': 'Trial of Cutaneous T-cell Lymphoma Therapy WP1220 Fully Enrolled', 'source': 'Lymphoma News Today', 'date': 'Aug 30, 2019', 'snippet': 'Read about the completed enrollment in a clinical trial of WP1220, a \ntopical treatment candidate for patients with cutaneous T-cell...', 'thumbnail': 'https://serpapi.com/searches/6723040a15c74058c296703c/images/2bdfca8836019330cd37f5bb32635b53483deaad6896aad11cbde7736b66dade.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9216471910476685}",,,,,,,,,,['neutral'],neutral,1 NCT05715528,"{'position': 1, 'link': 'https://www.mountsinai.org/clinical-trials/study-of-obeldesivir-in-nonhospitalized-participants-with-covid-19', 'title': 'Study of Obeldesivir in Nonhospitalized Participants With COVID-19', 'source': 'Mount Sinai', 'date': 'Jul 21, 2023', 'snippet': 'The goal of this clinical study is to test if obeldesivir (formerly \nGS-5245) is safe and effective for the treatment of coronavirus disease \n2019 (COVID-19)', 'thumbnail': 'https://serpapi.com/searches/672304dd15c7405910f66883/images/96b39b058265ad4b8df2b4760a454e9ccbf7a73f03b0e5ce9a8ac040e56da32e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8410796523094177}","{'position': 2, 'link': 'https://journals.asm.org/doi/10.1128/cmr.00119-23', 'title': 'COVID-19 therapeutics', 'source': 'ASM Journals', 'date': 'May 22, 2024', 'snippet': 'In this article, we review the antiviral activity, mechanism of action, \npharmacokinetics, and safety of COVID-19 antiviral therapies.', 'thumbnail': 'https://serpapi.com/searches/672304dd15c7405910f66883/images/96b39b058265ad4bd2908fe557bb42996952fb0294ec1e76198795e1fac61296.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9253212213516235}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00849134,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223003967', 'title': 'In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response', 'source': 'ScienceDirect.com', 'date': 'Mar 31, 2023', 'snippet': 'P2X7 receptor (P2X7R) is an ATP-gated ion channel involved in several \ninflammatory diseases and neuropathic pain. •. P2X7R activation triggers \nseveral...', 'thumbnail': 'https://serpapi.com/searches/672304f163a8447394d092df/images/7e5576961cca819373d5715d8a7bf6ceb2621dc59c287dc7fb54b6fab530fef6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8596197366714478}",,,,,,,,,,['neutral'],neutral,1 NCT04586153,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01323-9', 'title': 'Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial', 'source': 'Nature', 'date': 'Jan 30, 2023', 'snippet': 'Meplazumab, a humanized CD147 antibody, has shown favourable safety and \nefficacy in our previous clinical studies. In DEFLECT (NCT04586153)...', 'thumbnail': 'https://serpapi.com/searches/672304ec7f3719c320ef4d6f/images/e648e26c7a42b96de09fe1302a749fee071b866a43030cd76ea6d1fffee58b57.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5692375302314758}",,,,,,,,,,['neutral'],neutral,1 NCT01702129,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01536-y', 'title': 'Nanomedicine in cancer therapy - Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Aug 7, 2023', 'snippet': 'This Review outlines current and prospective strategies in the design of \ntumor tissue-, cell-, and organelle-targeted cancer nanomedicines.', 'thumbnail': 'https://serpapi.com/searches/67230515dda9d966e6c60674/images/345e56d83158c97983d87e923bad33b189793368a7f5046c945219d038b1928b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9363467693328857}",,,,,,,,,,['neutral'],neutral,1 NCT02054130,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1704064', 'title': 'Tezepelumab in Adults with Uncontrolled Asthma', 'source': 'The New England Journal of Medicine', 'date': 'Sep 7, 2017', 'snippet': 'In some patients with moderate-to-severe asthma, particularly those with \nnoneosinophilic inflammation, the disease remains uncontrolled.', 'thumbnail': 'https://serpapi.com/searches/6723055229e6fbf3a9ca447c/images/4c18499a8b46d6adbbf2f472bb2c704514916b6990f61374995f913a306a32e0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7404904365539551}","{'position': 2, 'link': 'https://www.empr.com/home/news/tezspire-approved-as-add-on-maintenance-treatment-for-severe-asthma/', 'title': 'Tezspire Approved as Add-On Maintenance Treatment for Severe Asthma', 'source': 'Medical Professionals Reference', 'date': 'Dec 20, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Tezspire™ \n(tezepelumab-ekko) for the add-on maintenance treatment of patients 12 \nyears...', 'thumbnail': 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'https://copdnewstoday.com/news/copd-therapy-daliresp-dosage-approved-by-fda-for-severe-cases/', 'title': 'COPD Therapy Daliresp Dosage Approved by FDA for Severe Cases', 'source': 'COPD News Today', 'date': 'Jan 29, 2018', 'snippet': ""Read about the FDA's approval of the 250 mcg dose of Daliresp as a \nfist-line therapy in patients with severe COPD."", 'thumbnail': 'https://serpapi.com/searches/67230576d771bd6ae74f94d7/images/e348386212a23ae26c4819144383c380c8c30e7cc808966a90482dd76ed68386.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8375487923622131}",,,,,,,,,,['neutral'],neutral,1 NCT03340064,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Keppra-levetiracetam', 'title': 'Levetiracetam (Keppra®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Epilepsy, A Study of Levetiracetam as Monotherapy or Adjunctive Treatment \nof Partial Seizures in Pediatric Epileptic Subjects Ranging From 1...', 'thumbnail': 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'source': 'The New England Journal of Medicine', 'date': 'Jan 25, 2017', 'snippet': 'The results of the HIV Prevention Trials Network 052 (ClinicalTrials.gov \nnumber, NCT00074581) study were released this past May, 30 years after the \nfirst...', 'thumbnail': 'https://serpapi.com/searches/672305e4a5e50243b325ae4b/images/51af563af5b8a0f96a8f70e192b5f3d5ae8ee31c2e00a6049482e196ac3a03b8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8415622711181641}",,,,,,,,,,['neutral'],neutral,1 NCT01694849,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-022-01119-3', 'title': 'Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)', 'source': 'Nature', 'date': 'Aug 13, 2022', 'snippet': 'In this review, we discussed recent developments in etiology and \nprospective therapeutic targets, as well as pharmacological candidates in \npre/clinical trials...', 'thumbnail': 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for pruritus therapies', 'source': 'Nature', 'date': 'Sep 8, 2017', 'snippet': 'Pruritus, or itching, is the unpleasant sensation that causes a desire to \nscratch. Chronic pruritus can be a debilitating manifestation of...', 'thumbnail': 'https://serpapi.com/searches/672306b815c7405910f66aa5/images/84e12545c2bb23610e604521f6ec44d076a3ca7b1221cdd4de5fd38c3e6e9e17.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7680660486221313}",,,,,,,,,,['negative'],negative,0 NCT03221257,"{'position': 1, 'link': 'https://sclerodermanews.com/news/phase-2-trial-of-cellcept-plus-esbriet-for-ssc-ild-enrolling-in-us/', 'title': 'Phase 2 Trial of CellCept Plus Esbriet for SSc-ILD Enrolling in US', 'source': 'Scleroderma News', 'date': 'Aug 31, 2020', 'snippet': 'The Scleroderma Lung Study III (SLSIII), a Phase 2 clinical trial of oral \nCellCept (mycophenolate mofetil) alone or in combination with...', 'thumbnail': 'https://serpapi.com/searches/672306c47b05caaa46af2d34/images/8f9cc5487d86b1c5c2a29d3bd7f0dacfd99734bad93dad63e0f9988a51ae2dd1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.907543420791626}",,,,,,,,,,['neutral'],neutral,1 NCT02656498,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-89797-x', 'title': 'Combination of automated brain volumetry on MRI and quantitative tau deposition on THK-5351 PET to support diagnosis of Alzheimer’s disease', 'source': 'Nature', 'date': 'May 14, 2021', 'snippet': ""Imaging biomarkers support the diagnosis of Alzheimer's disease (AD). We \naimed to determine whether combining automated brain volumetry on..."", 'thumbnail': 'https://serpapi.com/searches/67230735ee46823ed9be00d4/images/0d9f5be1e9b6a5740628bcdba19ab34aabb1bea3a27ce72d776470146f5c83b3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9096342325210571}",,,,,,,,,,['neutral'],neutral,1 NCT02876835,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2113380', 'title': 'Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis', 'source': 'The New England Journal of Medicine', 'date': 'Nov 5, 2021', 'snippet': 'Daprodustat is an oral hypoxia-inducible factor prolyl hydroxylase \ninhibitor. In patients with chronic kidney disease (CKD) who are not...', 'thumbnail': 'https://serpapi.com/searches/6723073d71b0e875fe4d67d8/images/f829126ba1837eb193766e321c6557c57cbf306c894bbf66e46800c1f48f00fe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5780116319656372}",,,,,,,,,,['neutral'],neutral,1 NCT04753606,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01936-7', 'title': 'Lipid lowering effects of the CETP inhibitor obicetrapib in combination with high-intensity statins: a randomized phase 2 trial', 'source': 'Nature', 'date': 'Aug 11, 2022', 'snippet': 'Global guidelines for the management of high-cardiovascular-risk patients \ninclude aggressive goals for low-density lipoprotein cholesterol...', 'thumbnail': 'https://serpapi.com/searches/672307b6fab273ad73e134ec/images/37d8aaf6ecb022422b2e33114a94f3b80428f262c35aa849f9250964e654ae0b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8734360337257385}",,,,,,,,,,['neutral'],neutral,1 NCT03533257,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/amx0035-improves-core-alzheimers-related-biomarkers-study/', 'title': 'Oral AMX0035 found to improve core Alzheimer’s-related biomarkers', 'source': ""Alzheimer's News Today"", 'date': 'Aug 29, 2024', 'snippet': ""Amylyx Pharmaceuticals' oral therapy candidate AMX0035 improves levels of \nseveral biomarkers associated with Alzheimer's, per a new..."", 'thumbnail': 'https://serpapi.com/searches/672307cf2c566da2e24005a4/images/86a77f6b5f44c98795a6fab2de6508ac182dcf1175d1f0a0344e0befa1380b5b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5265592336654663}",,,,,,,,,,['neutral'],neutral,1 NCT04060199,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/ns-pharma-shares-preliminary-results-of-viltolarsen-ns-065--ncnp-01-phase-3-clinical-trial-racer53-study-302155379.html', 'title': 'NS Pharma Shares Preliminary Results of Viltolarsen (NS-065 / NCNP-01) Phase 3 Clinical Trial (RACER53 Study)', 'source': 'PR Newswire', 'date': 'May 27, 2024', 'snippet': 'It has received preliminary analysis results from the global Phase 3 \nclinical trial (RACER53 study, NCT04060199) of NS-065/NCNP-01 (generic \nname: viltolarsen).', 'thumbnail': 'https://serpapi.com/searches/672307ece9b691ecd065ad02/images/08bfec3beab092ceffd5c000668479333c4c4cfb5e754db4747b84eb8ff07144.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8659732937812805}",,,,,,,,,,['neutral'],neutral,1 NCT00074737,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01589-z', 'title': 'Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials', 'source': 'Nature', 'date': 'Sep 6, 2023', 'snippet': 'In this review, we focus on the recent development of drug discovery \ntargeting “undruggable” proteins and their application in clinic.', 'thumbnail': 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0.6499823331832886}",,,,,,,,,,['neutral'],neutral,1 NCT01722331,"{'position': 1, 'link': 'https://www.dermatologyadvisor.com/cch/il-23-antagonists-in-the-treatment-of-plaque-psoriasis/', 'title': 'IL-23 Antagonists in the Treatment of Plaque Psoriasis', 'source': 'Dermatology Advisor', 'date': 'May 17, 2024', 'snippet': 'Three selective IL-23 inhibitors are currently approved for the treatment \nof plaque psoriasis: guselkumab, risankizumab, and tildrakizumab.', 'thumbnail': 'https://serpapi.com/searches/672308bacf32e07355990aa6/images/1b94f8b2f978e2528a212b19653eb88d326258f7ac3bd3604c8401de2958871d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.890917956829071}",,,,,,,,,,['neutral'],neutral,1 NCT05632211,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2023/12/04/in-early-trial-avt05-shows-similar-pharmacological-profile-to-simponi/', 'title': 'In early trial, AVT05 shows similar pharmacological profile to Simponi', 'source': 'Ankylosing Spondylitis News', 'date': 'Dec 4, 2023', 'snippet': ""AVT05, Alvotech's biosimilar candidate to treat ankylosing spondylitis, \nshowed a similar pharmacological profile to Simponi (golimumab)."", 'thumbnail': 'https://serpapi.com/searches/672308eb5f97783800f33060/images/604cbc87fbb27f426cf1ed9fa558595e43fec10bc245a920408fb98ef7880d9f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8694635629653931}",,,,,,,,,,['neutral'],neutral,1 NCT04377711,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/ciclesonide-metered-dose-inhaler-alvesco-symptomatic-covid-19-trial/', 'title': 'Mixed Results for Ciclesonide Metered-Dose Inhaler in COVID-19 Study', 'source': 'Medical Professionals Reference', 'date': 'Apr 15, 2021', 'snippet': 'Topline results were announced from a phase 3 study evaluating the efficacy \nand safety of ciclesonide metered-dose inhaler (Alvesco; Covis \nPharmaceuticals)', 'thumbnail': 'https://serpapi.com/searches/67230a2f1a5b54c4951a8c69/images/0cbcc6a778231793543537febca43aac29528d200e060085d0f888d0e777c5d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8548741340637207}",,,,,,,,,,['neutral'],neutral,1 NCT02981303,"{'position': 1, 'link': 'https://melanomanewstoday.com/2017/06/01/biothera-to-present-initial-trial-results-combo-therapy-melanoma-breast-cancer/', 'title': 'Initial Trial Results in Advanced Melanoma to Be Presented by Biothera', 'source': 'Melanoma News Today', 'date': 'Jun 1, 2017', 'snippet': 'Biothera Pharmaceuticals will present the detailed study design of the \nIMPRIME-1 clinical trial at the upcoming 2017 ASCO Annual Meeting...', 'thumbnail': 'https://serpapi.com/searches/67230a30c82127bb8ea5bf81/images/8fb858dc8924246c3d9af3326d2f0777056b1f1ece3c9c2076169f6685ce9b0e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9139280915260315}",,,,,,,,,,['neutral'],neutral,1 NCT02689284,"{'position': 1, 'link': 'https://www.onclive.com/view/fda-grants-margetuximab-orphan-drug-status-for-gastric-cancer', 'title': 'FDA Grants Margetuximab Orphan Drug Status for Gastric Cancer', 'source': 'OncLive', 'date': 'Jun 5, 2020', 'snippet': 'The FDA has granted margetuximab an Orphan Drug designation for the \ntreatment of patients with gastric and gastroesophageal junction cancer.', 'thumbnail': 'https://serpapi.com/searches/67230a38d0253e8b77108e2c/images/2bb9d735fa1183ad2f66b8ab74a19e1e6fdf7fc5f36cc17f89bee0f2b16e9024.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8816794753074646}",,,,,,,,,,['neutral'],neutral,1 NCT00594568,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1210951', 'title': ""A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease"", 'source': 'The New England Journal of Medicine', 'date': 'Jul 25, 2013', 'snippet': ""Alzheimer's disease is characterized by the presence of cortical \namyloid-beta (Aβ) protein plaques, which result from the sequential \naction..."", 'thumbnail': 'https://serpapi.com/searches/67230a4d23a4b50ac51e6a20/images/d5f351c2cfd987cdfb307fbde2ac18abdbafafc68e26460443f4c0119d26e7f7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8145344257354736}",,,,,,,,,,['neutral'],neutral,1 NCT03891524,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2113194', 'title': 'Milvexian for the Prevention of Venous Thromboembolism', 'source': 'The New England Journal of Medicine', 'date': 'Nov 15, 2021', 'snippet': 'Factor XIa inhibitors for the prevention and treatment of venous and \narterial thromboembolism may be more effective and result in less...', 'thumbnail': 'https://serpapi.com/searches/67230a8375f974afac11385c/images/b536ae0e83e2eaf5c06f29c6829360238c5dd015617cd59b62964e974402b598.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7155522108078003}",,,,,,,,,,['neutral'],neutral,1 NCT00943826,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1308345', 'title': 'Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma', 'source': 'The New England Journal of Medicine', 'date': 'Feb 20, 2014', 'snippet': 'In this phase 3 study, we evaluated the effect of the addition of \nbevacizumab to radiotherapy–temozolomide for the treatment of newly \ndiagnosed glioblastoma.', 'thumbnail': 'https://serpapi.com/searches/67230aa9efad21930504ef84/images/b7b3b76407e72bc2f3ccaa3aad28df232280daf156a08807e9331c0d19763930.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9009138345718384}",,,,,,,,,,['neutral'],neutral,1 NCT03579459,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0264410X23012963', 'title': 'A phase 3 study evaluating the lot consistency, immunogenicity, safety, and tolerability of a Clostridioides difficile vaccine in healthy adults 65 to 85 years of age', 'source': 'ScienceDirect.com', 'date': 'Dec 7, 2023', 'snippet': 'Three doses (Months 0,1,6) of toxoid-based C difficile vaccine induced \nrobust neutralizing antibody responses and were well tolerated in healthy \nparticipants...', 'thumbnail': 'https://serpapi.com/searches/67230ac3483e5b863e7166b6/images/24c2ac4a1951bdbaf9a1be692643de011390a7d769ee95c810f649b9fe19afc4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7878576517105103}",,,,,,,,,,['neutral'],neutral,1 NCT02926768,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01589-z', 'title': 'Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials', 'source': 'Nature', 'date': 'Sep 6, 2023', 'snippet': 'In this review, we focus on the recent development of drug discovery \ntargeting “undruggable” proteins and their application in clinic.', 'thumbnail': 'https://serpapi.com/searches/67230b624677bf0e20da2509/images/b31af61af41a899a71685ed505045974f98f6929ef0573420a45efae60071dba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8479585647583008}",,,,,,,,,,['neutral'],neutral,1 NCT03321513,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/type-step-therapy-effective-strategy-diabetic-eye-disease', 'title': 'A type of ‘step therapy’ is an effective strategy for diabetic eye disease', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jul 14, 2022', 'snippet': 'NIH-funded clinical trial finds that starting with a cheaper drug and \nswitching to a more expensive drug as needed leads to good vision...', 'thumbnail': 'https://serpapi.com/searches/67230b6831030010587ad5c6/images/42ffb5949db0a7adee553d91ed5378fe3871c39349551f26d55a8337b2bebdae.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6853460073471069}",,,,,,,,,,['positive'],positive,1 NCT00112931,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/reports/ash-2022-follicular-lymphoma-trials-show-promising-results/', 'title': 'ASH 2022: Trials Show Promising Results in Follicular Lymphoma', 'source': 'Cancer Therapy Advisor', 'date': 'Dec 20, 2022', 'snippet': 'Results from 4 trials presented at the 2022 ASH Annual Meeting may help \ninform the treatment of newly diagnosed and relapsed/refractory follicular \nlymphoma (FL...', 'thumbnail': 'https://serpapi.com/searches/67230b70f963e765fe78c987/images/8ed157d06a53eb12f5d73387624570af23dfad4d93e4d84a6d219dbd0ba75cc7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7179461121559143}",,,,,,,,,,['positive'],positive,1 NCT04744363,"{'position': 1, 'link': 'https://www.pharmacytimes.com/view/fda-approves-ustekinumab-biosimilar-to-stelara-for-treatment-of-plaque-psoriasis', 'title': 'FDA Approves Ustekinumab Biosimilar to Stelara for Treatment of Plaque Psoriasis', 'source': 'Pharmacy Times', 'date': 'Apr 17, 2024', 'snippet': 'Ustekinumab (Stelara; Janssen Immunology) is a human monoclonal antibody \nthat treats immune-mediated diseases such as psoriasis and...', 'thumbnail': 'https://serpapi.com/searches/67230ba0400bd56961859d57/images/9928ea78c70d193b8f014436f995e97f5c30beebb636e5e5eaed0da3f119ee56.png', 'sentiment': 'neutral', 'sentiment_prob': 0.846770167350769}",,,,,,,,,,['neutral'],neutral,1 NCT01363388,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/chemocentryx-on-track-present-topline-data-advocate-trial-avacopan/', 'title': ""AAV: ADVOCATE Trial's Topline Data Expected to be Presented This Year"", 'source': 'ANCA Vasculitis News', 'date': 'May 14, 2019', 'snippet': 'ChemoCentryx remains on track to report topline results later this year \nfrom its ongoing Phase 3 clinical trial assessing the safety and...', 'thumbnail': 'https://serpapi.com/searches/67230be36531cbe579007554/images/0478e52860f851d0e47cdb818462c106efe1fe18d50414bdcd78a390ccb037d5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8710752725601196}","{'position': 2, 'link': 'https://ancavasculitisnews.com/news/rituxan-soliris-combo-may-replace-glucocorticoids-aav-treatment/', 'title': 'For AAV, Rituxan-Soliris Combo May Replace Glucocorticoids, Study Says', 'source': 'ANCA Vasculitis News', 'date': 'May 30, 2019', 'snippet': 'A combination of Rituxan and Soliris may be used to replace glucocorticoids \nfor the treatment of patients with severe AAV, a case report...', 'thumbnail': 'https://serpapi.com/searches/67230be36531cbe579007554/images/0478e52860f851d02c70f090a6987ce8372236465fc911654cb4558a782b2463.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9202865362167358}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03664518,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.27141', 'title': 'Efficacy and safety of eltrombopag in the treatment of immune thrombocytopenia patients with hepatitis B virus infection: A prospective, multicenter, single arm, phase II trial', 'source': 'Wiley Online Library', 'date': 'Oct 26, 2023', 'snippet': 'Hepatitis B virus (HBV) infection is the most common chronic viral \ninfection worldwide. Epidemiological data showed that the hepatitis virus...', 'thumbnail': 'https://serpapi.com/searches/67230d50069e577bfa331901/images/33e4f31b28d213d763660e80e9b3b740dab10c1bd437f07ece17e19c1f4ef2ce.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7033538818359375}",,,,,,,,,,['neutral'],neutral,1 NCT04056065,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/circ.142.suppl_4.278', 'title': 'Abstract 278: A Novel Resuscitative Agent, Centhaquine (Lyfaquin®), has the Potential to Treat Acute Kidney Injury Following Hemorrhagic Shock', 'source': 'American Heart Association Journals', 'date': 'Nov 9, 2020', 'snippet': 'Introduction: Centhaquine (CQ) is being developed as a first-in-class \nresuscitative agent to treat hemorrhagic shock.', 'thumbnail': 'https://serpapi.com/searches/67230c68d11a89a60d58fcfc/images/f4de02842a658031e775b82b6ea6dfc5178c02d73742e894d58ef49aaadc8840.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8361145257949829}",,,,,,,,,,['neutral'],neutral,1 NCT03558152,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223000616', 'title': 'Role of Interleukin-22 in ulcerative colitis', 'source': 'ScienceDirect.com', 'date': 'Jan 23, 2023', 'snippet': 'IL-22 plays a crucial role in UC, which is closely related to AhR, STAT3, \nCARD9, MSC, Treg, RA and intestinal flora. •. In clinical practice, IL-22 \nand its...', 'thumbnail': 'https://serpapi.com/searches/67230c6ca775f2f8ec0e64d4/images/10a326e80f49d9e6c7e8bdd73fabbed0cc4a678bb7964e058110be49ce574dd7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.879794716835022}",,,,,,,,,,['neutral'],neutral,1 NCT05083260,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/parkinsons-trial-anti-inflammatory-ne3107-may-open-summer/', 'title': 'Phase 2 trial of NE3107, an anti-inflammatory, may open in summer', 'source': ""Parkinson's News Today"", 'date': 'Mar 18, 2024', 'snippet': 'BioVie is planning to launch in late summer a Phase 2b clinical trial of \nNE3107, its investigational anti-inflammatory small molecule, as an initial \nand stand-...', 'thumbnail': 'https://serpapi.com/searches/67230cbfcf32e07355990feb/images/a278315a2f09288a129106ead6aeca25eab9c00651d000a7cf49db502776db8a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.790367066860199}","{'position': 2, 'link': 'https://www.globenewswire.com/News-Release/2022/12/05/2567854/0/En/BioVie-Announces-Positive-Results-for-NE3107-in-Parkinson-s-and-Alzheimer-s-Phase-2-Trials.html', 'title': 'BioVie Announces Positive Results for NE3107 in Parkinson’s and Alzheimer’s Phase 2 Trials', 'source': 'GlobeNewswire', 'date': 'Dec 5, 2022', 'snippet': ""NE3107-treated patients experienced greater motor control in Parkinson's \ntrial Patients treated with the combination of NE3107 and levodopa..."", 'thumbnail': 'https://serpapi.com/searches/67230cbfcf32e07355990feb/images/a278315a2f09288aec592acb8b2a3b6d7e92676b624fdc51ae97cbc3491ff130.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5283809304237366}","{'position': 3, 'link': 'https://parkinsonsnewstoday.com/news/parkinsons-adding-ne3107-levodopa-aids-motor-nonmotor-benefits/', 'title': 'NE3107 added to levodopa enhances motor, non-motor benefits', 'source': ""Parkinson's News Today"", 'date': 'Mar 4, 2024', 'snippet': ""Adding NE3107 to carbidopa/levodopa therapy eases motor and non-motor \nsymptoms in people with Parkinson's disease, a Phase 2a trial shows."", 'thumbnail': 'https://serpapi.com/searches/67230cbfcf32e07355990feb/images/a278315a2f09288a1ebcd2590b81f711fa6af39acba1d17595e2d1cfe7f47216.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7265336513519287}","{'position': 4, 'link': 'https://parkinsonsnewstoday.com/news/add-on-ne3107-now-bezisterim-eases-parkinsons-symptoms/', 'title': 'Add-on NE3107, now bezisterim, eases Parkinson’s symptoms', 'source': ""Parkinson's News Today"", 'date': 'May 29, 2024', 'snippet': ""NE3107, now bezisterim, eases Parkinson's motor and nonmotor symptoms when \nused along with other therapies, study data showed."", 'thumbnail': 'https://serpapi.com/searches/67230cbfcf32e07355990feb/images/a278315a2f09288a735558571bb4d7e6c227c56413fbf575db5ed19869a0234c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.748104453086853}",,,,,,,"['neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT04234204,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/astellas-announces-topline-12-week-results-from-phase-3-study-of-fezolinetant-for-the-nonhormonal-treatment-of-vasomotor-symptoms-in-women-in-asia-301502322.html', 'title': 'Astellas Announces Topline 12-week Results from Phase 3 Study of Fezolinetant for the Nonhormonal Treatment of Vasomotor Symptoms in Women in Asia', 'source': 'PR Newswire', 'date': 'Mar 14, 2022', 'snippet': ""Astellas' MOONLIGHT 1TM clinical trial evaluating investigational \nfezolinetant 30 mg administered once daily."", 'thumbnail': 'https://serpapi.com/searches/67230cc1d78a985ac5d5ce53/images/0f22063710c0aedc4b518e0d1e1f982556201a478d7a4e8ee9a0c1ea3b83c131.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9121507406234741}",,,,,,,,,,['neutral'],neutral,1 NCT02743897,"{'position': 1, 'link': 'https://hepatitisnewstoday.com/2017/05/02/doctors-transplant-kidneys-with-hepatitis-c-and-then-cure-the-infection/', 'title': 'Doctors Transplant Kidneys with Hepatitis C, Then Cure Recipients’ Infection', 'source': 'Hepatitis News Today', 'date': 'May 2, 2017', 'snippet': 'Ten clinical trial participants were cured of hepatitis C after receiving a \nkidney transplant from deceased donors who were infected with the virus.', 'thumbnail': 'https://serpapi.com/searches/67230ccd71b0e875b539cfce/images/6ebd8d506156a29c264bca444156fe64409f3377d18e2ba782e61d22b19e4314.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8083324432373047}",,,,,,,,,,['neutral'],neutral,1 NCT04250337,"{'position': 1, 'link': 'https://www.empr.com/news/ebglyss-approved-for-moderate-to-severe-atopic-dermatitis/', 'title': 'Ebglyss Approved for Moderate to Severe Atopic Dermatitis', 'source': 'Medical Professionals Reference', 'date': '1 month ago', 'snippet': 'The Food and Drug Administration (FDA) has approved Ebglyss™ \n(lebrikizumab-lbkz) for the treatment of adult and pediatric patients aged \n12...', 'thumbnail': 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NCT04306146,"{'position': 1, 'link': 'https://www.nature.com/articles/s41386-023-01614-3', 'title': 'Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry | Neuropsychopharmacology', 'source': 'Nature', 'date': 'Jun 27, 2023', 'snippet': 'NMDA receptor modulators have long been considered as potential treatments \nfor psychiatric disorders including depression and schizophrenia, \nneurodevelopmental...', 'thumbnail': 'https://serpapi.com/searches/67230d00f79a012cbdab47ce/images/50dfdb7875c32b2c53c2db3745e64cb732550e3722dce6619a670df2f9af6498.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7463937401771545}",,,,,,,,,,['neutral'],neutral,1 NCT03375294,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/does-nitrous-oxide-help-veterans-with-ptsd/', 'title': 'Does Nitrous Oxide Help Veterans With Posttraumatic Stress Disorder? A Case Series', 'source': 'Psychiatrist.com', 'date': 'Jun 30, 2020', 'snippet': 'This case series investigates the potential for nitrous oxide to rapidly \nreduce symptoms of posttraumatic stress disorder. Did it help the 3...', 'thumbnail': 'https://serpapi.com/searches/67230d11e95dbf8877425eef/images/2ca76daf3ffd45580e5332a42d989fcb35c328cbd2a6679d13f096a93a5bb66c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7989832162857056}",,,,,,,,,,['neutral'],neutral,1 NCT03485911,"{'position': 1, 'link': 'https://angioedemanews.com/news/trial-data-long-term-orladeyo-hae-patients-safe-effective/', 'title': 'Long-term Orladeyo safe, effective in HAE patients: Trial data', 'source': 'Angioedema News', 'date': 'Dec 21, 2023', 'snippet': 'Long-term prophylaxis, or preventive treatment, with Orladeyo \n(berotralstat) is well tolerated, and results in sustained reductions in \nswelling attacks and...', 'thumbnail': 'https://serpapi.com/searches/67230d28b4fe87d275d34e82/images/bfe31008c14e5ddb84f5e2e7ab8335ce02cc5abf9c908fcaa144aba069ccc1e1.png', 'sentiment': 'positive', 'sentiment_prob': 0.5627046823501587}","{'position': 2, 'link': 'https://angioedemanews.com/news/orladeyo-set-to-launch-by-years-end-if-approved-biocryst-says/', 'title': ""HAE Drug Orladeyo to Launch by Year's End if Approved, BioCryst Says"", 'source': 'Angioedema News', 'date': 'Aug 19, 2020', 'snippet': ""BioCryst Pharmaceuticals will launch Orladeyo (berotralstat) by year's end \nif this oral drug for hereditary angioedema is approved,..."", 'thumbnail': 'https://serpapi.com/searches/67230d28b4fe87d275d34e82/images/bfe31008c14e5ddb4a439b054c62d1072178ed3fb65c356e0f33cdde8a24c09a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.840570867061615}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04523129,"{'position': 1, 'link': 'https://www.medscape.com/viewarticle/993024', 'title': 'FDA Approves Second Waterless Solution for Dry Eye Disease', 'source': 'Medscape', 'date': 'Jun 9, 2023', 'snippet': 'The US Food and Drug Administration (FDA) has approved the first waterless \ncyclosporine-based solution for treating the signs and symptoms of dry eye \ndisease.', 'thumbnail': 'https://serpapi.com/searches/67230d5a7ebde58f676f15f4/images/49f2635955ee55ae1cfc47560b498a8dd8c60744d3b3b3973f590f5d3009e9a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7421690225601196}","{'position': 2, 'link': 'https://www.empr.com/home/news/water-free-dry-eye-disease-therapy-vevye-gets-fda-approval/', 'title': 'Water-Free Dry Eye Disease Therapy Vevye Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Jun 8, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Vevye™ (cyclosporine \nophthalmic solution) 0.1% for the treatment of the signs and...', 'thumbnail': 'https://serpapi.com/searches/67230d5a7ebde58f676f15f4/images/49f2635955ee55ae20c5c556fe3d519f4a23b019c673adda1e9e718019de0e51.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6431905627250671}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02534844,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/experimental-treatment-niemann-pick-disease-type-c1-appears-safe-effective', 'title': 'Experimental treatment for Niemann-Pick disease type C1 appears safe, effective', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Aug 11, 2017', 'snippet': 'NIH-led clinical trial suggests that drug slows progression of rare \nneurological disease.', 'thumbnail': 'https://serpapi.com/searches/67230d658f2bc20cba22ce6d/images/0cb8c2d1f1e5ba000cd0ad607d67dd56dd2c6f077794e7df60c3ef95644d76e9.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.561607837677002}","{'position': 2, 'link': 'https://www.europeanpharmaceuticalreview.com/news/65610/experimental-treatment-niemann-pick/', 'title': 'Experimental treatment for Niemann-Pick disease appears safe', 'source': 'European Pharmaceutical Review', 'date': 'Aug 14, 2017', 'snippet': 'An experimental drug has appeared to slow the progression of Niemann-Pick \ndisease type C1 (NPC1), the drug, 2-hydroxypropyl-beta-cyclodextrin \n(VTS-270), is...', 'thumbnail': 'https://serpapi.com/searches/67230d658f2bc20cba22ce6d/images/0cb8c2d1f1e5ba00434b9b55e234d334c06363494937c9758e209022df3e7a3a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7627475261688232}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02650895,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S1550413122003047', 'title': 'CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder', 'source': 'ScienceDirect.com', 'date': 'Aug 2, 2022', 'snippet': 'We report that the CD24-Siglec-E axis, but not other Siglecs, is a key \nsuppressor of obesity-related metabolic dysfunction.', 'thumbnail': 'https://serpapi.com/searches/67230d9768831e823dc94227/images/f24d290357d293d1a0081ecbf03f663e63993bd9be88d3296fc22008cd45f3a7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.873424768447876}",,,,,,,,,,['neutral'],neutral,1 NCT02570997,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/ct1812/', 'title': 'Elayta (CT1812)', 'source': ""Alzheimer's News Today"", 'date': 'Apr 7, 2018', 'snippet': ""CT1812 is an oral medication being developed by Cognition Therapeutics, now \nin clinical testing, to possibly treat mild-to-moderate Alzheimer's disease \nby..."", 'thumbnail': 'https://serpapi.com/searches/67230de8acf7f8291ac55e17/images/3e201025f406e8c99bfc7e1a3451f6d3405bdb6fa698ff92d9b20fc5613c5965.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8871570825576782}",,,,,,,,,,['neutral'],neutral,1 NCT04430855,"{'position': 1, 'link': 'https://www.termedia.pl/Hidradenitis-suppurativa-a-new-therapeutic-approach-for-an-old-disease,7,54608,1,1.html', 'title': 'Hidradenitis suppurativa: a new therapeutic approach for an old disease', 'source': 'Termedia', 'date': 'Aug 12, 2024', 'snippet': 'Hidradenitis suppurativa (HS) is a chronic inflammatory disease \ncharacterised by recurrent painful nodules, abscesses, fistulas and \nscarring...', 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'https://www.nature.com/articles/s41392-022-01213-6', 'title': 'Phase I study of camrelizumab in patients with advanced solid tumors', 'source': 'Nature', 'date': 'Feb 1, 2023', 'snippet': 'Dear Editor,. Camrelizumab (SHR-1210) is a humanized monoclonal antibody \n(mAb) that binds to programmed cell death protein 1 (PD-1).', 'thumbnail': 'https://serpapi.com/searches/67230e659819f3396e1cec01/images/c258920e670871cb052f944d4a6cffc0663d36406da0497e0c30c1815d757cbd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8546786904335022}",,,,,,,,,,['neutral'],neutral,1 NCT03829241,"{'position': 1, 'link': 'https://www.bioworld.com/articles/670274-first-patient-enrolled-in-phase-iii-study-of-troriluzole-in-generalized-anxiety-disorder', 'title': 'First patient enrolled in phase III study of troriluzole in generalized anxiety disorder', 'source': 'BioWorld MedTech', 'date': 'Feb 21, 2019', 'snippet': 'Biohaven Pharmaceutical announced that it has enrolled its first patient in \na phase III clinical trial assessing the efficacy and safety of...', 'thumbnail': 'https://serpapi.com/searches/67230e9049ea558318e554a7/images/73ee5437a5326f36e4d0535c2dda21a2489810117816ddfd173331553527ab5a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8288338780403137}",,,,,,,,,,['neutral'],neutral,1 NCT02950051,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2213093', 'title': 'First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'May 10, 2023', 'snippet': 'Randomized trials of venetoclax plus anti-CD20 antibodies as first-line \ntreatment in fit patients (i.e., those with a low burden of...', 'thumbnail': 'https://serpapi.com/searches/67230e96be1497773c62e4cf/images/9eeec4d3a9f422c988b5eccce0de25f94582ff88b6e15368c33a408056ab5329.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8882309794425964}","{'position': 2, 'link': 'https://www.onclive.com/view/fixed-duration-venetoclax-based-combos-maintain-benefit-in-frontline-cll', 'title': 'Fixed-Duration Venetoclax-Based Combos Maintain Benefit in Frontline CLL', 'source': 'OncLive', 'date': 'Jul 17, 2024', 'snippet': 'Additional follow-up from the phase 3 GAIA/CLL13 trial (NCT02950051) \ndemonstrated that fixed-duration treatment with venetoclax (Venclexta)...', 'thumbnail': 'https://serpapi.com/searches/67230e96be1497773c62e4cf/images/9eeec4d3a9f422c9319f43029ba14cd89b8ad34ceaa2b9bb36ca3ec0c9bcb4b2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8059571981430054}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00004041,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2021.621831/full', 'title': 'Current Approaches for Glioma Gene Therapy and Virotherapy', 'source': 'Frontiers', 'date': 'Jun 27, 2024', 'snippet': 'Glioblastoma (GBM) is the most common and aggressive primary brain tumor in \nthe adult population and it carries a dismal prognosis. Inefficient drug...', 'thumbnail': 'https://serpapi.com/searches/67230e9ac024d129ff76bac7/images/b07a8e06b6fd94adbc550e6a8e16f8a2ece80b7d22c7633e5dfb6fb05a42c7e7.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7528362274169922}",,,,,,,,,,['negative'],negative,0 NCT01101438,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-021-00275-z', 'title': 'Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial', 'source': 'Nature', 'date': 'Jun 8, 2021', 'snippet': 'Metformin may exert anticancer effects through indirect (mediated by \nmetabolic changes) or direct mechanisms. 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'date': 'Jul 30, 2024', 'snippet': 'Approval is based on data from two Phase III studies in branch and central \nretinal vein occlusion (RVO) showing early and sustained vision...', 'thumbnail': 'https://serpapi.com/searches/67230edec7d4a15f9713c5d9/images/0f704900f53993e39f98ee774d831a8ee43541fa72f4699cc6fa50172e9ec23d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6009171605110168}",,,,,,,,,,['neutral'],neutral,1 NCT03021499,"{'position': 1, 'link': 'https://lupusnewstoday.com/news/lupkynis-approved-japan-treat-lupus-nephritis/', 'title': 'Lupkynis approved in Japan to treat lupus nephritis', 'source': 'Lupus News Today', 'date': '4 weeks ago', 'snippet': 'Lupkynis (voclosporin) is now approved in Japan to treat lupus nephritis, a \ncomplication of lupus marked by kidney damage and inflammation.', 'thumbnail': 'https://serpapi.com/searches/67230ee40d379fd08d19993c/images/9aaaa852a9d992b0e4217915a4956133bab7054e189fce334282ad3717d6e991.png', 'sentiment': 'neutral', 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inhibitor that reduces left \nventricular outflow tract gradients by mitigating cardiac \nhypercontractility.', 'thumbnail': 'https://serpapi.com/searches/67230eec0f2a2ca3ad67ea5e/images/9d175d7cbb422ba8c4086ebe9738f1a44c356e9b74ef8b41b2290d169036e6a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8317034840583801}","{'position': 2, 'link': 'https://consultqd.clevelandclinic.org/advances-in-hypertrophic-cardiomyopathy-therapy-valor-hcm-may-be-just-the-beginning', 'title': 'Advances in Hypertrophic Cardiomyopathy Therapy: VALOR-HCM May Be Just the Beginning', 'source': 'Cleveland Clinic', 'date': 'Jan 27, 2023', 'snippet': 'An abundance of promising studies are on the horizon. \n22-HVI-3509429_obstructive-hypertrophic-cardiomyopathy_650x450. When \nCleveland Clinic...', 'thumbnail': 'https://serpapi.com/searches/67230eec0f2a2ca3ad67ea5e/images/9d175d7cbb422ba88e8ba016fb55fc2cbfddd2e9fe450f6c84b2d9bfca9d31fe.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8903656005859375}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02012491,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1715726', 'title': 'Mifepristone Pretreatment for the Medical Management of Early Pregnancy Loss', 'source': 'The New England Journal of Medicine', 'date': 'Jun 6, 2018', 'snippet': 'Medical management of early pregnancy loss is an alternative to uterine \naspiration, but standard medical treatment with misoprostol commonly...', 'thumbnail': 'https://serpapi.com/searches/67230f02e281ee018cee3229/images/95a2f9dbe9fe6023c3fd0e1a009f1ac87f7b5d72a335d47f79f38f53e8b04abd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6485427021980286}",,,,,,,,,,['neutral'],neutral,1 NCT04738123,"{'position': 1, 'link': 'https://www.psychiatryadvisor.com/news/karxt-efficacy-safety-acute-psychosis-schizophrenia/', 'title': 'KarXT Demonstrates Efficacy, Safety for Acute Psychosis in Schizophrenia', 'source': 'Psychiatry Advisor', 'date': 'May 10, 2024', 'snippet': 'Xanomeline-trospium chloride (KarXT) was efficacious and well-tolerated \namong individuals with schizophrenia experiencing acute psychosis, \naccording to phase 3...', 'thumbnail': 'https://serpapi.com/searches/67230f0e4677bf0e20da28e5/images/bea66a2131ba78ed8273400e92656ec9bd1123a70ee0452d0c2c20f8f6df265d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5799948573112488}","{'position': 2, 'link': 'https://www.empr.com/news/cobenfy-approved-for-adult-patients-with-schizophrenia/', 'title': 'Cobenfy Approved for Adult Patients with Schizophrenia', 'source': 'Medical Professionals Reference', 'date': '1 month ago', 'snippet': 'The Food and Drug Administration (FDA) has approved Cobenfy (xanomeline and \ntrospium chloride) for the treatment of adults with schizophrenia.', 'thumbnail': 'https://serpapi.com/searches/67230f0e4677bf0e20da28e5/images/bea66a2131ba78ed28fc9f13c573701252d44c93941777e7276150ffb5a7d21b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7815037369728088}","{'position': 3, 'link': 'https://www.psychiatrist.com/jcp/antipsychotic-efficacy-of-karxt-xanomeline-trospium/', 'title': 'Antipsychotic Efficacy of KarXT (Xanomeline−Trospium): Post Hoc Analysis of Positive and Negative Syndrome Scale Categorical Response Rates, Time Course of Response, and Symptom Domains of Response in a Phase 2 Study', 'source': 'Psychiatrist.com', 'date': 'May 11, 2022', 'snippet': 'KarXT provided clinically meaningful responder rates on PANSS total score \ncompared with placebo at each response threshold, providing further support \nof the...', 'thumbnail': 'https://serpapi.com/searches/67230f0e4677bf0e20da28e5/images/bea66a2131ba78ed4e5bde2db5a4ce20c94fc62c1de3bef0249b91e5a776faff.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8605852127075195}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02454634,"{'position': 1, 'link': 'https://www.nature.com/articles/s41586-021-03363-z', 'title': 'A vaccine targeting mutant IDH1 in newly diagnosed glioma', 'source': 'Nature', 'date': 'Mar 24, 2021', 'snippet': 'Mutated isocitrate dehydrogenase 1 (IDH1) defines a molecularly distinct \nsubtype of diffuse glioma1–3. The most common IDH1 mutation in...', 'thumbnail': 'https://serpapi.com/searches/67230f6b0f1a33107cb1c4df/images/c1d536ababd97c1164cf73e792f983398cafbf23ba48f17ed9c6c8a8fc7d9b49.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8800758719444275}",,,,,,,,,,['neutral'],neutral,1 NCT04436744,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00268-1/fulltext', 'title': 'Neoadjuvant palbociclib plus either giredestrant or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase 2 study', 'source': 'The Lancet', 'date': 'Nov 1, 2023', 'snippet': 'The development of more potent selective oestrogen receptor antagonists and \ndegraders (SERDs) that can be orally administered could help to...', 'thumbnail': 'https://serpapi.com/searches/67230fb058e433496eb9514e/images/b249f61a2b348ad6e0ce373fa34e4749aed0855a5fccdd76479c7452d83f4de0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8613340258598328}",,,,,,,,,,['neutral'],neutral,1 NCT03276572,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/reports/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/', 'title': '225Ac-J591 Yields Responses in Difficult-to-Treat Metastatic Prostate Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Dec 2, 2023', 'snippet': 'The radiopharmaceutical 225Ac-J591 produced responses in patients with \nmetastatic prostate cancer in a phase 1 study.', 'thumbnail': 'https://serpapi.com/searches/67230fba16779391e19aa8c2/images/9ca3fae3d60dc79991c0deb1074a6330befdad3b0568f7d055c42a7e91e6ee89.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.566058874130249}",,,,,,,,,,['neutral'],neutral,1 NCT04751682,"{'position': 1, 'link': 'https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00025-1/fulltext', 'title': 'Intranasal COVID-19 vaccines: From bench to bed - eBioMedicine', 'source': 'The Lancet', 'date': 'Jan 24, 2022', 'snippet': 'Intranasal (IN) vaccination method has been demonstrated to be potent in \ninducing both mucosal and systemic immune responses.', 'thumbnail': 'https://serpapi.com/searches/67230fbd81bab738a9d5d3c3/images/b165a205af28f3dc02cf4b43d5f1d2673c3c8a9563706099efba1036ebc513b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7254720330238342}",,,,,,,,,,['neutral'],neutral,1 NCT01830855,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1614474', 'title': 'A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults', 'source': 'The New England Journal of Medicine', 'date': 'Dec 14, 2017', 'snippet': 'MenB-FHbp is a licensed meningococcal B vaccine targeting factor H–binding \nprotein. Two phase 3 studies assessed the safety of the vaccine...', 'thumbnail': 'https://serpapi.com/searches/67230fd6e6862ba37958da22/images/4cce7afd12191fb0a4632cf8832b2f721bea04cac89770d5fb1c395799ff7f68.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8811836242675781}",,,,,,,,,,['neutral'],neutral,1 NCT00638690,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1014618', 'title': 'Abiraterone and Increased Survival in Metastatic Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'May 26, 2011', 'snippet': 'We evaluated whether abiraterone acetate, an inhibitor of androgen \nbiosynthesis, prolongs overall survival among patients with metastatic \ncastration-resistant...', 'thumbnail': 'https://serpapi.com/searches/67230fef7ac731301bf68a26/images/e62f22b06b41aec62ec2fa667d4f844be9a79da7aea30666b8f69b58e43d0433.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8556347489356995}","{'position': 2, 'link': 'https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/s12874-021-01460-1', 'title': 'Comparing current and emerging practice models for the extrapolation of survival data: a simulation study and case-study', 'source': 'BMC Medical Research Methodology', 'date': 'Nov 27, 2021', 'snippet': 'Estimates of future survival can be a key evidence source when deciding if \na medical treatment should be funded. Current practice is to use...', 'thumbnail': 'https://serpapi.com/searches/67230fef7ac731301bf68a26/images/e62f22b06b41aec6aebd21ea9d931f5665aa72d3361ebdb1cb55622020c4ceaf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9093783497810364}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03872791,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45160-y', 'title': 'The anti-PD-L1/CTLA-4 bispecific antibody KN046 in combination with nab-paclitaxel in first-line treatment of metastatic triple-negative breast cancer: a multicenter phase II trial', 'source': 'Nature', 'date': 'Feb 3, 2024', 'snippet': 'This multicenter, phase II study (NCT03872791) aims to evaluate the \nefficacy and safety of the anti-PD-L1/CTLA-4 bispecific antibody KN046...', 'thumbnail': 'https://serpapi.com/searches/67230fffc117a9c5638bae4e/images/fcbb8c170d6b48ac111446ca888b23d265544ab465f232b66995bc49002de810.png', 'sentiment': 'neutral', 'sentiment_prob': 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1050 clinical trials are registered at FDA.gov that explore \nmultipotent mesenchymal stromal cells (MSCs) for nearly every clinical...', 'thumbnail': 'https://serpapi.com/searches/67231073a2e99c352b092c9e/images/644a2d1af410b196da7c0c738856a862203bffdae880c058808d6519d4569470.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7360979318618774}",,,,,,,,,,['neutral'],neutral,1 NCT01618136,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-0916-5', 'title': 'First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor', 'source': 'Nature', 'date': 'Jun 11, 2020', 'snippet': 'This phase 1 study examined the safety, maximum-tolerated dose (MTD) and \nantitumour activity of E7449, a novel PARP 1/2 and tankyrase 1/2 inhibitor.', 'thumbnail': 'https://serpapi.com/searches/672312190f2a2ca367b4e116/images/03866fb5a411893a900edd0616e742be4b9471ca93c250afb9415c937941c233.png', 'sentiment': 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ciloleucel and lisocabtagene \nmaraleucel, panelists reflect on the real-world use of CAR T-cell...', 'thumbnail': 'https://serpapi.com/searches/672311311f3d4bf2c8b58811/images/5c5c798be4998f312a30b63fada84062a2779560db49039a68f5776daf229866.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9351696968078613}","{'position': 3, 'link': 'https://lymphomanewstoday.com/2017/10/19/fda-approves-yescarta-first-car-t-cell-therapy-for-lymphoma/', 'title': 'FDA Approves Yescarta, First CAR T-cell Therapy for Lymphoma', 'source': 'Lymphoma News Today', 'date': 'Oct 19, 2017', 'snippet': ""The U.S. Food and Drug Administration (FDA) approved Kite Pharma's Yescarta \n(axicabtagene ciloleucel) for the treatment of relapsed or..."", 'thumbnail': 'https://serpapi.com/searches/672311311f3d4bf2c8b58811/images/5c5c798be4998f315fe41efdb8d55ef5f8de52a655cdac6e416b89f1c68cdb4e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6092697381973267}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 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\ntreatment — an investigational, bone marrow-derived, medicinal signaling...', 'thumbnail': 'https://serpapi.com/searches/67231160fbde0d1890ff18c8/images/99c7cead1369a635799fec59348814510a5cd9561f0b8f5f2c685d2114375f26.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9124618768692017}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00098397,"{'position': 1, 'link': 'https://www.nature.com/articles/s41388-024-03054-9', 'title': 'A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance | Oncogene', 'source': 'Nature', 'date': 'May 8, 2024', 'snippet': 'Epigenetic regulation established during development to maintain patterns \nof transcriptional expression and silencing for metabolism and...', 'thumbnail': 'https://serpapi.com/searches/6723122c0d379fd08d199c60/images/d644a99fbad5194303befde404f96b25501849cebdc720cddbcd972de6838bfa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9292553067207336}",,,,,,,,,,['neutral'],neutral,1 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""More people aren't prescribing steroids for pneumonia. They all conclude \nfairly strongly that there is a benefit – and not just any benefit, but a \nmortality..."", 'thumbnail': 'https://serpapi.com/searches/6723125dc7d4a15f9713c8a5/images/139b34aa36248f6036ee3e460b4cf6f07d4fcf20341940147810eddead930c12.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7739244103431702}",,,,,,,,,,['neutral'],neutral,1 NCT02491983,"{'position': 1, 'link': 'https://www.onclive.com/view/real-world-data-on-cdk4-6-inhibitors-in-hr-her2--metastatic-breast-cancer-and-ongoing-trials', 'title': 'Real-World Data on CDK4/6 Inhibitors in HR+/HER2- Metastatic Breast Cancer and Ongoing Trials', 'source': 'OncLive', 'date': 'Jul 25, 2023', 'snippet': 'Experts on HR+/HER2- breast cancer review recent real-world data on CDK4/6 \ninhibitors and share excitement about first-line trials that have...', 'thumbnail': 'https://serpapi.com/searches/6723126ef7adbf910b6c30cf/images/0c4251ef092f9c0870564422a1a09dc6bc104441fe8996102289dc17ba2f836e.jpeg', 'sentiment': 'neutral', 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a novel oral Janus kinase inhibitor that is \nbeing investigated as a targeted immunomodulator and...', 'thumbnail': 'https://serpapi.com/searches/6723140e15c74058c29680df/images/28932a8b1ce589bc58a5f56ba36f7bba9923c819ab0082680577d1a0804ccb6d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9134076237678528}",,,,,,,,,,['neutral'],neutral,1 NCT04583969,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-study-aims-identify-promising-covid-19-treatments-larger-clinical-trials', 'title': 'NIH study aims to identify promising COVID-19 treatments for larger clinical trials', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Oct 13, 2020', 'snippet': 'The ACTIV-5 Big Effects Trial will enroll adult volunteers hospitalized \nwith COVID-19.', 'thumbnail': 'https://serpapi.com/searches/6723153dbcd6529d7b4e6bd3/images/4818b38eb8bc396c2ce82ac13f1bd46246fdc46172a680d8f15fb8fe54c42a25.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'Mar 18, 2019', 'snippet': 'Aerpio Pharmaceuticals acknowledged the failure of its lead pipeline \ncandidate in a Phase IIb trial in patients with moderate to severe \nnon-proliferative...', 'thumbnail': 'https://serpapi.com/searches/67231591efad2193710cbb43/images/56bd0254e8675e02f56288cd1a42b1895406adac9fb3581226a231353e943a2f.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8294599652290344}",,,,,,,,,,['negative'],negative,0 NCT04650399,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00641-4/fulltext', 'title': 'Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'Jun 12, 2023', 'snippet': 'VLA1553 is a live-attenuated vaccine candidate for active immunisation and \nprevention of disease caused by chikungunya virus.', 'thumbnail': 'https://serpapi.com/searches/672315a5fc183dcdb20b298a/images/6113295576c3de4a53804996e65732c6cf65baa8db80fa3d7fc5e669163375f1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7965168356895447}","{'position': 2, 'link': 'https://valneva.com/press-release/valneva-reports-positive-pivotal-phase-3-immunogenicity-data-in-adolescents-for-its-single-shot-chikungunya-vaccine-candidate/', 'title': 'Valneva Reports Positive Pivotal Phase 3 Immunogenicity Data in Adolescents for its Single-Shot Chikungunya Vaccine Candidate', 'source': 'Valneva', 'date': 'Nov 13, 2023', 'snippet': 'Valneva reported positive pivotal immunogenicity data for its single-dose \nchikungunya virus (CHIKV) vaccine candidate VLA1553.', 'thumbnail': 'https://serpapi.com/searches/672315a5fc183dcdb20b298a/images/6113295576c3de4a1c53f3c89096ac155c4c11720378c471a241c42765e798c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7725892066955566}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01431274,"{'position': 1, 'link': 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2017', 'snippet': 'Active RA patients whose response to methotrexate (MTX) therapy was \ninsufficient showed improvement when MTX was combined with filgotinib,...', 'thumbnail': 'https://serpapi.com/searches/672314700053c7013aadc7c2/images/b9bc293e52453c29260cafdf4cf6362e9520a2f49ffd187f60f6dfe8609fb82d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5993414521217346}",,,,,,,,,,['neutral'],neutral,1 NCT05653856,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/early/2024/07/18/jnumed.123.267126', 'title': '61Cu-PSMA–Targeted PET for Prostate Cancer: From Radiotracer Development to First-in-Human Imaging', 'source': 'Journal of Nuclear Medicine', 'date': 'Jul 18, 2024', 'snippet': 'Tais Basaco Bernabeu, Rosalba Mansi, Luigi Del Pozzo, Sandra Zanger, \nRaghuvir H. Gaonkar, Lisa McDougall, Francesco De Rose,...', 'thumbnail': 'https://serpapi.com/searches/67231484a882788f7cddb568/images/4819b152a82617bd4603750e4f7bc9e3d36006d0d9b3b364500f79f10c68c60f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.94233238697052}",,,,,,,,,,['neutral'],neutral,1 NCT00061594,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa062655', 'title': 'Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration', 'source': 'The New England Journal of Medicine', 'date': 'Oct 5, 2006', 'snippet': 'During the first year of this 2-year, multicenter, double-blind study, we \nrandomly assigned patients in a 1:1:1 ratio to receive monthly...', 'thumbnail': 'https://serpapi.com/searches/6723148cfcd69e8306c91d72/images/4f036387153424e38222d88909aa7b37d61d40032655d40a4d631bd07c8c74f1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9034882187843323}",,,,,,,,,,['neutral'],neutral,1 NCT03197766,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1813446', 'title': 'C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia', 'source': 'The New England Journal of Medicine', 'date': 'Jun 18, 2019', 'snippet': 'Achondroplasia is a genetic disorder that inhibits endochondral \nossification, resulting in disproportionate short stature and clinically \nsignificant medical...', 'thumbnail': 'https://serpapi.com/searches/67231494240793cd7e65ac7c/images/7cef2d09141bee2ddac030061e3b17dcfab4a4b074e0be001499a2fb4d1d653c.png', 'sentiment': 'negative', 'sentiment_prob': 0.5959500074386597}","{'position': 2, 'link': 'https://www.empr.com/home/news/voxzogo-gets-fda-approval-for-achondroplasia/', 'title': 'Voxzogo Gets FDA Approval for Achondroplasia', 'source': 'Medical Professionals Reference', 'date': 'Nov 19, 2021', 'snippet': 'The Food and Drug Administration (FDA) has granted accelerated approval to \nVoxzogo (vosoritide) injection, a C-type natriuretic peptide...', 'thumbnail': 'https://serpapi.com/searches/67231494240793cd7e65ac7c/images/7cef2d09141bee2dc69d21a265e28fbc1547a7ccd87c1c38d76109c7e4326903.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5544262528419495}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT01546038,"{'position': 1, 'link': 'https://www.researchgate.net/figure/History-of-AML-therapies-Timeline-of-approved-clinical-therapies-in-the-United-States_fig1_347673267', 'title': 'Fig. 1 History of AML therapies. Timeline of approved clinical...', 'source': 'ResearchGate', 'date': 'May 8, 2022', 'snippet': 'For many years, treatment options for AML remained stagnant, with the \nstandard 7+3 regimen of cytarabine and daunorubicin and SCT being the only \noption for...', 'thumbnail': 'https://serpapi.com/searches/672314a339e232ed6dec4a01/images/660d615952f0ae6e30fea235a5b11ce2d8ea2ca9b0b49e9348d63b501934f972.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5696207880973816}",,,,,,,,,,['neutral'],neutral,1 NCT03227471,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/cf-patients-with-mental-health-issues-benefit-from-lower-kaftrio-dose/', 'title': 'CF patients with mental health issues benefit from lower Kaftrio dose', 'source': 'Cystic Fibrosis News Today', 'date': 'May 23, 2023', 'snippet': 'Reducing the dose of Kaftrio should be weighed for cystic fibrosis patients \nwho report cognitive, psychological side effects, a study shows.', 'thumbnail': 'https://serpapi.com/searches/6723150da86921c0f30c3eef/images/f4ea918baf9eaf66805897d83375f031b7c9fb41ff12fb591295ce6c820408f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8073989152908325}",,,,,,,,,,['neutral'],neutral,1 NCT03334253,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/low-dose-atropine-eyedrops-no-better-placebo-slowing-myopia-progression', 'title': 'Low-dose atropine eyedrops no better than placebo for slowing myopia progression', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jul 13, 2023', 'snippet': 'NIH-funded trial underscores need for more research to head off high myopia.', 'thumbnail': 'https://serpapi.com/searches/6723151e90adce4a729ebdc4/images/55393f3c33d9778d6374840caab50e80e81faeed09145d6573e05a855759117e.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7677732110023499}",,,,,,,,,,['negative'],negative,0 NCT02689505,"{'position': 1, 'link': 'https://www.researchgate.net/publication/384902278_Comprehensive_biomarker_and_modeling_approach_to_support_dose_finding_for_BI_836880_a_VEGFAng-2_inhibitor', 'title': '(PDF) Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor', 'source': 'ResearchGate', 'date': '2 weeks ago', 'snippet': 'PDF | Background BI 836880 is a humanized bispecific nanobody® that binds \nto and blocks vascular endothelial growth factor (VEGF) and...', 'thumbnail': 'https://serpapi.com/searches/672315f0ef60cb338d94cfa3/images/f0c3129b72328330b7ab9173415a7c2b7ade4761ff722565670be82d7df8e434.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.89641934633255}",,,,,,,,,,['neutral'],neutral,1 NCT02297698,"{'position': 1, 'link': 'https://www.thepharmaletter.com/pharmaceutical/galena-tanks-as-it-pulls-the-plug-on-neuvax-trial', 'title': 'Galena tanks as it pulls the plug on NeuVax trial', 'source': 'The Pharma Letter', 'date': 'Jun 29, 2016', 'snippet': 'More on this story... Midatech to acquire Zuplenz from Galena Biopharma. \nPharmaceutical · Midatech to acquire Zuplenz from Galena Biopharma.', 'thumbnail': 'https://serpapi.com/searches/672315f5708e2e045142103a/images/7f1cc5c8e7ea88972ff88e21f1ba3a40ff62b0d89ee219190b1051d270bcb3bc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7706093788146973}",,,,,,,,,,['neutral'],neutral,1 NCT00932893,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1214886', 'title': 'Crizotinib versus Chemotherapy in Advanced ALK -Positive Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 1, 2013', 'snippet': 'In single-group studies, chromosomal rearrangements of the anaplastic \nlymphoma kinase gene (ALK) have been associated with marked clinical...', 'thumbnail': 'https://serpapi.com/searches/6723160ef410449024f45a2d/images/eec97444a11dc39a5912a3bb5fb453fd4d1e433f0273d7ae2b8297e1ef3b39af.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8160057067871094}",,,,,,,,,,['neutral'],neutral,1 NCT04251910,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/on-demand-bxcl501-seen-ease-alzheimers-agitation-phase-3-trial/', 'title': ""BXCL501 seen to ease Alzheimer's agitation in Phase 3 trial |..."", 'source': ""Alzheimer's News Today"", 'date': 'Jun 30, 2023', 'snippet': ""On-demand treatment with BXCL501 was found to significantly ease episodes \nof agitation for Alzheimer's patients in a Phase 3 clinical trial."", 'thumbnail': 'https://serpapi.com/searches/6723162f8b84c41a795d67cc/images/c295280e81d96bb5493dbed8aace6554cc10699dc18328a2772604ef505ea3e3.png', 'sentiment': 'positive', 'sentiment_prob': 0.5488898754119873}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/dexmedetomidine-acute-treatment-agitation-associated-dementia-breakthrough-therapy/', 'title': 'Dexmedetomidine Oral Film Gets Breakthrough Tx Status for Acute Agitation With Dementia', 'source': 'Medical Professionals Reference', 'date': 'Mar 15, 2021', 'snippet': 'The Food and Drug Administration (FDA) has granted Breakthrough Therapy \ndesignation to BXCL501 (dexmedetomidine; BioXcel Therapeutics) for the \nacute treatment...', 'thumbnail': 'https://serpapi.com/searches/6723162f8b84c41a795d67cc/images/c295280e81d96bb5c77381c2d26048301c199273a9ccd40606e122eda4bce2c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6966283321380615}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00073528,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-82318-w', 'title': 'Clinical data mining reveals analgesic effects of lapatinib in cancer patients', 'source': 'Nature', 'date': 'Feb 11, 2021', 'snippet': 'Microsomal prostaglandin E2 synthase 1 (mPGES-1) is recognized as a \npromising target for a next generation of anti-inflammatory drugs that...', 'thumbnail': 'https://serpapi.com/searches/67231666e45f334e584f169f/images/329c59e4f9a83aac9a8098d882055cba10e04bf54c32ccc9c45813d4203d580a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7619749307632446}",,,,,,,,,,['neutral'],neutral,1 NCT04818346,"{'position': 1, 'link': 'https://www.dermatologytimes.com/view/incyte-announces-positive-52-week-data-at-eadv-of-povorcitinib-for-extensive-nonsegmental-vitiligo', 'title': 'Incyte Announces Positive 52-Week Data at EADV of Povorcitinib for Extensive Nonsegmental Vitiligo', 'source': 'Dermatology Times', 'date': 'Oct 12, 2023', 'snippet': 'Incyte recently announced positive 52-week data from a phase 2b clinical \ntrial evaluating the safety and efficacy of povorcitinib...', 'thumbnail': 'https://serpapi.com/searches/6723167efab273ad2fda63f6/images/81c6d658ee10ac2d0278079b1991ac8816070e82a44c91e999eadd3ba734167b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5580693483352661}",,,,,,,,,,['neutral'],neutral,1 NCT02194426,"{'position': 1, 'link': 'https://ascopubs.org/doi/abs/10.1200/JCO.20.00596', 'title': 'First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors', 'source': 'ASCO Publications', 'date': 'Dec 10, 2020', 'snippet': 'PURPOSEA first-in-human study was performed with MP0250, a DARPin drug \ncandidate. MP0250 specifically inhibits both vascular endothelial...', 'thumbnail': 'https://serpapi.com/searches/67231693adc33b93e06ec020/images/d6211da28c0599f457348fb35db6819e8a058ca5b1c18f7103a1a3c659182c9a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9029291272163391}",,,,,,,,,,['neutral'],neutral,1 NCT01740297,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0530-6', 'title': 'Patterns of response with talimogene laherparepvec in combination with ipilimumab or ipilimumab alone in metastatic unresectable melanoma', 'source': 'Nature', 'date': 'Jul 29, 2019', 'snippet': 'We explored response patterns from a phase 2 study evaluating patients with \nunresectable stage IIIB–IVM1c malignant melanoma who received T-VEC plus \nipilimumab...', 'thumbnail': 'https://serpapi.com/searches/672316b417a2e2f68afad022/images/cd16ace245bb2725dcf98aa2ee405ecffae20c0a7ba9deb44abde437789b6b46.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8980348110198975}",,,,,,,,,,['neutral'],neutral,1 NCT03790709,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/early-alzheimers-anavex-2-73-slows-cognitive-decline-neurodegeneration/', 'title': 'Neurodegeneration and cognitive decline slow with Anavex 2-73', 'source': ""Alzheimer's News Today"", 'date': 'Sep 15, 2023', 'snippet': ""Anavex is preparing meetings with regulatory authorities in the U.S., \nEurope, and Asia-Pacific to discuss Anavex 2-73's potential approval."", 'thumbnail': 'https://serpapi.com/searches/672316cec1c8dda1bab16cdc/images/34c457f18dbd072b960828fbcb3969bfe059e915d33280daac80544d148d7b4e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8807852864265442}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/news/anavex-seek-ema-approval-shaky-results/', 'title': 'Anavex seek EMA approval despite shaky pivotal Alzheimer’s trial data', 'source': 'Clinical Trials Arena', 'date': 'Jul 29, 2024', 'snippet': ""The clinical benefit of blarcamesine was observed, but only one co-primary \nendpoint was met in the Alzheimer's disease trial."", 'thumbnail': 'https://serpapi.com/searches/672316cec1c8dda1bab16cdc/images/34c457f18dbd072b617b29db84858078c3bf7380cd2facc712310b8cf02a2d5a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7897889018058777}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00036439,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa050516', 'title': 'Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 31, 2017', 'snippet': 'Two randomized, double-blind, placebo-controlled studies — the Active \nUlcerative Colitis Trials 1 and 2 (ACT 1 and ACT 2, respectively) — \nevaluated the...', 'thumbnail': 'https://serpapi.com/searches/672317119fd309c82152a443/images/bef9416cf6c79ba8e4d7c785d3e37b27077a65ba2906498f36f6b8a0ce4f2276.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9349810481071472}",,,,,,,,,,['neutral'],neutral,1 NCT02393859,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-022-01770-3', 'title': 'Improved survival and MRD remission with blinatumomab vs. chemotherapy in children with first high-risk relapse B-ALL', 'source': 'Nature', 'date': 'Dec 8, 2022', 'snippet': 'For children with high-risk, first-relapse B-cell precursor acute \nlymphoblastic leukemia (B-ALL), allogeneic hematopoietic stem cell...', 'thumbnail': 'https://serpapi.com/searches/67231721b57db86eba9938dd/images/ece58ee0ffee17fc39048ef747486e5773a78fcfeb6726cb1c9df66ac83582f4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7785382270812988}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/fda-gives-full-approval-to-blinatumomab-in-mrd-positive-b-cell-all', 'title': 'FDA Gives Full Approval to Blinatumomab in MRD-Positive B-Cell ALL', 'source': 'Cancer Network', 'date': 'Jun 21, 2023', 'snippet': 'Blinatumomab has been granted full approval by the FDA for patients with \nB-cell acute lymphoblastic leukemia and minimal residual disease of...', 'thumbnail': 'https://serpapi.com/searches/67231721b57db86eba9938dd/images/ece58ee0ffee17fc3eac902eb48d85f19c40023b4b853a06bf451c3ab02c8fad.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5017969608306885}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05157841,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/exparel-application-under-review-for-sciatic-and-femoral-nerve-blocks/', 'title': 'Exparel Application Under Review for Sciatic and Femoral Nerve Blocks', 'source': 'Medical Professionals Reference', 'date': 'Mar 31, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted the supplemental New \nDrug Application (sNDA) for Exparel (bupivacaine liposome injectable \nsuspension)', 'thumbnail': 'https://serpapi.com/searches/672317ca4a4a1d0f98dca306/images/88dd6ec26fed4b4810325a44803bcc3f0055cf1443bfa80a8fcd002c7e896ccc.jpeg', 'sentiment': 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Activation of the PI3K/AKT/mTOR pathway...', 'thumbnail': 'https://serpapi.com/searches/672317e3dc969f1f1120c1ce/images/c655d8d5408e77858add1448600543efe0ce2c52cbb173b8803e742d9b19917b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9116150736808777}",,,,,,,,,,['neutral'],neutral,1 NCT04424316,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2216480', 'title': 'Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants', 'source': 'The New England Journal of Medicine', 'date': 'Apr 5, 2023', 'snippet': 'Whether vaccination during pregnancy could reduce the burden of respiratory \nsyncytial virus (RSV)–associated lower respiratory tract illness...', 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba33842bf0f8ec0027468cc82d72c709fe28f630d4c8c9a2faaf2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8381577730178833}","{'position': 2, 'link': 'https://www.pfizer.com/sites/default/files/investors/financial_reports/annual_reports/2022/story/a-step-closer-in-the-fight-against-respiratory-syncytial-virus/', 'title': 'Pfizer progresses novel vaccine candidate for respiratory syncytial virus (RSV) called PF-06928316 or RSVpreF', 'source': 'Pfizer', 'date': 'Jan 3, 2024', 'snippet': 'Respiratory syncytial virus (RSV) is a contagious, common and pervasive \ncause of acute respiratory illness among older adults and young children.1 \nIn the...', 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba3380ec014eae04f2921b17cde9e5088c27202189b6ee0132cf4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7410576343536377}","{'position': 3, 'link': 'https://www.businesswire.com/news/home/20230821069057/en/U.S.-FDA-Approves-ABRYSVO%E2%84%A2-Pfizer%E2%80%99s-Vaccine-for-the-Prevention-of-Respiratory-Syncytial-Virus-RSV-in-Infants-Through-Active-Immunization-of-Pregnant-Individuals-32-36-Weeks-of-Gestational-Age', 'title': 'U.S. FDA Approves ABRYSVO™, Pfizer’s Vaccine for the Prevention of Respiratory Syncytial Virus (RSV) in Infants Through Active Immunization of Pregnant Individuals 32-36 Weeks of Gestational Age', 'source': 'Business Wire', 'date': 'Aug 21, 2023', 'snippet': ""... FDA's decision is based on data from the pivotal Phase 3 clinical trial \nin more than 7,000 pregnant individuals, and including their..."", 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba33814fef5c682b56e89ad4301574a1d8c2084fdc72bfe2ad1b2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8601066470146179}","{'position': 4, 'link': 'https://www.drugtopics.com/view/fda-approves-abrysvo-for-adults-18-59-at-increased-risk-for-rsv', 'title': 'FDA Approves Abrysvo for Adults 18-59 at Increased Risk for RSV', 'source': 'Drug Topics', 'date': '1 week ago', 'snippet': ""Pfizer's respiratory syncytial virus (RSV) vaccine Abrysvo has been \napproved by the FDA for the prevention RSV-associated of lower..."", 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba33824c7cb5dcdc24926c6857287e7b78fef5b06b3b0a901a9ad.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.857796311378479}","{'position': 5, 'link': 'https://www.prnewswire.com/apac/news-releases/pfizer-receives-authorization-from-health-authority-for-the-first-dual-indication-vaccine-approved-in-hong-kong-302139477.html', 'title': 'Pfizer Receives Authorization from Health Authority for the First Dual Indication Vaccine Approved in Hong Kong', 'source': 'PR Newswire', 'date': 'May 8, 2024', 'snippet': 'A Vaccine to Fight Against Respiratory Syncytial Virus (RSV) in Older \nAdults Aged 60 and Above and Infants (Through Maternal Immunization)...', 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba3382b442383cb6dc915935948b41b233eedd40494325ed6f5d7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8212655782699585}","{'position': 6, 'link': 'https://www.expresspharma.in/us-fda-approves-abrysvo-pfizers-maternal-rsv-vaccine-for-infants/', 'title': 'US FDA approves ABRYSVO, Pfizer’s maternal RSV vaccine for infants', 'source': 'Express Pharma', 'date': 'Aug 22, 2023', 'snippet': ""The US Food and Drug Administration (FDA) has approved ABRYSVO (Respiratory \nSyncytial Virus Vaccine), the company's bivalent RSV prefusion F (RSVpreF) \nvaccine."", 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba338d4fff9f08256f1f187c4fcf860c5f017c642e8b20e97b358.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7450793981552124}","{'position': 7, 'link': 'https://www.drugtopics.com/view/acip-votes-to-lower-recommended-age-of-pneumococcal-vaccination', 'title': 'ACIP Votes to Lower Recommended Age of Pneumococcal Vaccination', 'source': 'Drug Topics', 'date': '6 days ago', 'snippet': 'The CDC Advisory Committee on Immunization Practices (ACIP) has voted to \nlower recommended age for pneumococcal vaccination from 65 years to...', 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba338ca1c6af95a4935cf63052fc5410728082fe8294897caedef.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9366915822029114}","{'position': 8, 'link': 'https://www.drugtopics.com/view/novel-antifungal-treatment-approved-for-vaginal-candidiasis', 'title': 'Novel Antifungal Treatment Approved for Vaginal Candidiasis', 'source': 'Drug Topics', 'date': 'Jul 14, 2021', 'snippet': 'On June 2,2021, ibrexafungerp (Brexafemme; Scynexis, Inc) was approved by \nthe FDA for vulvovaginal candidiasis (VVC) in adult women and...', 'thumbnail': 'https://serpapi.com/searches/6723173ebe801338c03decbe/images/9b6859b670eba338c824db9a21cf1ca51229aee54c44fd02cdfc71e1ead19636.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8588642477989197}",,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03574753,"{'position': 1, 'link': 'https://fnih.org/our-programs/master-protocol-for-treatment-of-non-small-cell-lung-cancer-lung-map/', 'title': 'Master Protocol For Treatment Of Non-Small Cell Lung Cancer (Lung-MAP)', 'source': 'FNIH', 'date': 'Jun 1, 2023', 'snippet': 'A groundbreaking multi-center clinical trial that uses a multi-sub-study, \ntargeted screening approach to match patients, based on their unique tumor \nprofiles.', 'thumbnail': 'https://serpapi.com/searches/67231742fbde0d1847a3d935/images/121c36c7a9821398e4c73eb25cdef15aa6fbbe3bbe12b33ffa43f7200897e61b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.732329785823822}",,,,,,,,,,['neutral'],neutral,1 NCT03037385,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01931-y', 'title': 'Pan-cancer efficacy of pralsetinib in patients with RET fusion–positive solid tumors from the phase 1/2 ARROW trial', 'source': 'Nature', 'date': 'Aug 12, 2022', 'snippet': 'Oncogenic RET fusions occur in diverse cancers. Pralsetinib is a potent, \nselective inhibitor of RET receptor tyrosine kinase.', 'thumbnail': 'https://serpapi.com/searches/67231748e281ee0144eab124/images/fb1bb0e98a09b2b6e81f334d0c00739c67f45a175666566bded6fbdf896e899a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7561172842979431}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/fda-grants-regular-approval-to-pralsetinib-in-advanced-nsclc', 'title': 'FDA Grants Regular Approval to Pralsetinib in Advanced NSCLC', 'source': 'Cancer Network', 'date': 'Aug 9, 2023', 'snippet': 'Patients with metastatic RET fusion-positive non–small cell lung cancer may \nnow be treated with pralsetinib, which has been granted regular...', 'thumbnail': 'https://serpapi.com/searches/67231748e281ee0144eab124/images/fb1bb0e98a09b2b6e093249c1159a5d67835c2e837b8d21e55d3a09d2870d0d4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8916344046592712}","{'position': 3, 'link': 'https://ascopost.com/news/august-2023/fda-approves-pralsetinib-for-ret-fusion-positive-nsclc/', 'title': 'FDA Approves Pralsetinib for RET Fusion–Positive NSCLC', 'source': 'The ASCO Post', 'date': 'Aug 11, 2023', 'snippet': 'The US Food and Drug Administration (FDA) granted regular approval to \npralsetinib (Gavreto) for adults with metastatic RET fusion–positive \nnon–small cell lung...', 'thumbnail': 'https://serpapi.com/searches/67231748e281ee0144eab124/images/fb1bb0e98a09b2b6cc886e47f66bd3c9f7ddbb2cb0c770ecf24d19d3b4b0b1df.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6970062851905823}","{'position': 4, 'link': 'https://www.nature.com/articles/s41467-022-30908-1', 'title': 'Addressing challenges with real-world synthetic control arms to demonstrate the comparative effectiveness of Pralsetinib in non-small cell lung cancer', 'source': 'Nature', 'date': 'Jun 17, 2022', 'snippet': 'The study provides evidence in favour of pralsetinib as a first-line \ntreatment for RET fusion-positive aNSCLC.', 'thumbnail': 'https://serpapi.com/searches/67231748e281ee0144eab124/images/fb1bb0e98a09b2b6cea64d94d84dded52d62c871987761d441e1e5b3df2e152e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7061426043510437}","{'position': 5, 'link': 'https://www.empr.com/home/news/gavreto-granted-full-approval-for-ret-fusion-positive-nsclc/', 'title': 'Gavreto Granted Full Approval for RET Fusion-Positive NSCLC - MPR', 'source': 'Medical Professionals Reference', 'date': 'Aug 10, 2023', 'snippet': 'The Food and Drug Administration (FDA) has granted full approval to Gavreto \n(pralsetinib) for the treatment of adult patients with metastatic \nrearranged during...', 'thumbnail': 'https://serpapi.com/searches/67231748e281ee0144eab124/images/fb1bb0e98a09b2b639a62cf25c86c605e9bd2b711d08836c74c41e40a89b61af.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7846548557281494}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01458717,"{'position': 1, 'link': 'https://dailynews.ascopubs.org/do/contemporary-approaches-resectable-pancreatic-ductal-adenocarcinoma-reflexive-nuanced', 'title': 'Contemporary Approaches to Resectable Pancreatic Ductal Adenocarcinoma: Reflexive or Nuanced Utilization of Neoadjuvant Approaches?', 'source': 'ASCO Daily News', 'date': 'Apr 19, 2023', 'snippet': 'some groups advocate that an alternative approach—namely neoadjuvant \ntherapy (NAT) in all cases—is necessary to improve survival...', 'thumbnail': 'https://serpapi.com/searches/67231768b691a72d639a18dd/images/59818896186cfc06d5722712fb2052ee5aaa83765a42a3fcc9a879774af73ef0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.895675778388977}",,,,,,,,,,['neutral'],neutral,1 NCT02469155,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/lumateperone-treatment-schizophrenia-number-needed-treat-number-needed-harm-likelihood-helped-harmed/', 'title': 'Lumateperone for the Treatment of Schizophrenia: Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed', 'source': 'Psychiatrist.com', 'date': 'Mar 6, 2023', 'snippet': 'The benefit-risk assessment of lumateperone was favorable as measured by \nnumber-needed-to-treat and number-needed-to-harm analyses.', 'thumbnail': 'https://serpapi.com/searches/6723177d4791c4eca64d6bf9/images/ba747c52340847cf39dcb2ae1c4cb0a88e45b5c55bc3263cd473f17bbf02f0ac.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7699416875839233}",,,,,,,,,,['neutral'],neutral,1 NCT03930615,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-extended-prevymis-regimen-for-hsct-patients-at-risk-for-late-cmv/', 'title': 'FDA Approves Extended Prevymis Regimen for HSCT Patients at Risk for Late CMV', 'source': 'Medical Professionals Reference', 'date': 'Aug 9, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved the extended use of \nPrevymis (letermovir) from 100 to 200 days post-transplant for the \nprophylaxis of...', 'thumbnail': 'https://serpapi.com/searches/67231791069e577c4598c840/images/2c1198f8289b359d6c034c51e4c2b12ce46a6d31b4652586e6dea464043e0a23.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8427796363830566}",,,,,,,,,,['neutral'],neutral,1 NCT04091360,"{'position': 1, 'link': 'https://copdnewstoday.com/news/copd-treatment-pmdi-ensifentrine-improves-lung-function/', 'title': 'Treatment With pMDI Ensifentrine Found to Improve Lung Function', 'source': 'COPD News Today', 'date': 'Oct 18, 2021', 'snippet': 'Seven days of treatment with ensifentrine, given using a pressurized \nmetered-dose inhaler — called a pMDI — resulted in marked lung function...', 'thumbnail': 'https://serpapi.com/searches/6723179e75f974affaee9f77/images/ca1c9466ae750b2b6695eaab3a0bb8b67e9fb8f4dace76fd9f17daf25afd23e9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5474724769592285}","{'position': 2, 'link': 'https://copdnewstoday.com/news/ensifentrine-pressurized-dose-inhaler-formulation-showing-efficacy-copd-phase-2-trial/', 'title': 'Ensifentrine, in Pressurized Dose Inhaler, Showing Efficacy in...', 'source': 'COPD News Today', 'date': 'Apr 2, 2020', 'snippet': 'A single dose of a pressurized metered-dose inhaler formulation of \nensifentrine (RPL544) significantly improved lung function, compared to a \nplacebo.', 'thumbnail': 'https://serpapi.com/searches/6723179e75f974affaee9f77/images/ca1c9466ae750b2b1c5439af1098a76fa57d11662419a118834ca89384c3b040.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6491924524307251}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT01671150,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-16364-3', 'title': 'Interleukin-8 and depressive responses to an inflammatory challenge: secondary analysis of a randomized controlled trial', 'source': 'Nature', 'date': 'Jul 24, 2022', 'snippet': 'Emerging evidence suggests that interleukin (IL)-8 has a protective role in \nthe context of depression. Higher levels of IL-8 are associated...', 'thumbnail': 'https://serpapi.com/searches/6723179f690bb9df0c333405/images/65cbd8586e76e1bd3b07c0b387ecd9645f3d50571da01df9a98afefd8ed61841.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8534020781517029}",,,,,,,,,,['neutral'],neutral,1 NCT03077659,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.647110/full', 'title': 'Analysis of Clinical Trials on Therapies for Prostate Cancer in Mainland China and Globally from 2010 to 2020', 'source': 'Frontiers', 'date': 'Jun 30, 2023', 'snippet': 'The overall aging of the world population has contributed to the continuous \nupward trend in the incidence of prostate cancer (PC). Trials on PC therapy \nhave...', 'thumbnail': 'https://serpapi.com/searches/6723182f069e577bfa33228a/images/281f09b16baef784e2d86f9512abbda05595e22e0c59c0848f98eac1b57aa5dd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5001696944236755}",,,,,,,,,,['neutral'],neutral,1 NCT02065063,"{'position': 1, 'link': 'https://www.oncologynurseadvisor.com/news/triple-therapy-shows-promise-in-treatment-resistant-subtype-of-lung-cancer/', 'title': 'Triple Therapy Shows Promise in Treatment Resistant Subtype of Lung Cancer', 'source': 'Oncology Nurse Advisor', 'date': 'Jan 13, 2016', 'snippet': 'Lung cancers with KRAS-related gene mutations might benefit from a triple \ntherapy regimen of 2 experimental drugs plus radiation therapy.', 'thumbnail': 'https://serpapi.com/searches/6723183bb57db86f007ad600/images/9d35e773e2bb165c45b7123a4b4b9440899a05ea3c6336054e82de3654b6ce7b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7427494525909424}",,,,,,,,,,['neutral'],neutral,1 NCT01843530,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1155/2016/3930923', 'title': 'The Use of Plasma-Derived Complement C1-Esterase Inhibitor Concentrate (Berinert®) in the Treatment of Angiotensin Converting Enzyme-Inhibitor Related Angioedema', 'source': 'Wiley Online Library', 'date': 'Mar 31, 2016', 'snippet': 'We here present a case of severe angiotensin converting enzyme-inhibitor \nrelated angioedema (ACEi-AE) of the hypopharynx that completely resolved \nrapidly.', 'thumbnail': 'https://serpapi.com/searches/672319c8fab273ad73e14751/images/a13d72b24521c7e4cb064242724976190bf4f35462d80f9f54ead4854233b06a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8316097259521484}",,,,,,,,,,['neutral'],neutral,1 NCT02464605,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-27945-7', 'title': 'Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia', 'source': 'Nature', 'date': 'Jan 12, 2022', 'snippet': 'Biologic drugs have transformed the standard of care for many diseases. \nHowever, many biologics induce the formation of anti-drug antibodies...', 'thumbnail': 'https://serpapi.com/searches/6723193af3cbfaa09d7b197e/images/10e3587584f58a51cbb1bbde8ec7fd7e5c78eeb8ecf6cc2d1647127b0fb0eb61.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6858675479888916}",,,,,,,,,,['neutral'],neutral,1 NCT03606876,"{'position': 1, 'link': 'https://www.empr.com/home/news/generics-news/tofidence-tocilizumab-biosimilar-approved/', 'title': 'FDA Approves Tofidence, the First Biosimilar to Tocilizumab', 'source': 'Medical Professionals Reference', 'date': 'Oct 2, 2023', 'snippet': 'The Food and Drug Administration has approved Tofidence (tocilizumab-bavi), \nthe first biosimilar to Actemra (tocilizumab).', 'thumbnail': 'https://serpapi.com/searches/6723196aee46823ed9be12f4/images/4f18fc2711f2f81974f0c8ab8f151a948abe256ccf53bb329235828e86fd49c4.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5141994953155518}",,,,,,,,,,['positive'],positive,1 NCT01927159,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-36789-2', 'title': 'Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults', 'source': 'Nature', 'date': 'Mar 6, 2023', 'snippet': 'Adjuvant-containing subunit vaccines represent a promising approach for \nprotection against tuberculosis (TB), but current candidates require...', 'thumbnail': 'https://serpapi.com/searches/67231969c024d12a48a69cfb/images/538f5d41bdc9dc75ebef0558fe7f0583a14cf65433fccd2a1c99429a63fc1187.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6567094326019287}",,,,,,,,,,['neutral'],neutral,1 NCT02728752,"{'position': 1, 'link': 'https://www.specialtypharmacycontinuum.com/FDA-News/Article/07-21/FDA-Grants-New-Indication-for-Octagam-10-for-Adult-Dermatomyositis/64132', 'title': 'FDA Grants New Indication for Octagam 10% for Adult Dermatomyositis', 'source': 'Specialty Pharmacy Continuum', 'date': 'Apr 25, 2024', 'snippet': 'The FDA granted a new indication to Immune Globulin Intravenous (Human) \n(Octagam 10%, Octapharma USA), for the treatment of adult dermatomyositis.', 'thumbnail': 'https://serpapi.com/searches/672319740be2f63ada2a4ea3/images/7bdf924c9fe6c8f23bc6cc837d109b0da74e4be0d27f256de0853529d5f3de25.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7153904438018799}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20210720005999/en/FDA-Approves-Octapharma%E2%80%99s-Octagam%C2%AE-10-for-Adult-Dermatomyositis', 'title': 'FDA Approves Octapharma’s Octagam® 10% for Adult Dermatomyositis', 'source': 'Business Wire', 'date': 'Jul 20, 2021', 'snippet': 'PARAMUS, N.J.--(BUSINESS WIRE)--The U.S. Food and Drug Administration (FDA) \nhas granted approval to Octapharma USA for Octagam® 10% [Immune...', 'thumbnail': 'https://serpapi.com/searches/672319740be2f63ada2a4ea3/images/7bdf924c9fe6c8f2067d0cd4de90c29c7bd7c55cf0572dea6af81fe0511a2c7b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8596963286399841}","{'position': 3, 'link': 'https://www.businesswire.com/news/home/20210830005059/en/FDA-Orphan-Drug-Approval-Octapharma%E2%80%99s-Octagam%C2%AE-10-Receives-7-Years-of-Market-Exclusivity-for-Adult-Dermatomyositis', 'title': '10% Receives 7 Years of Market Exclusivity for Adult Dermatomyositis', 'source': 'Business Wire', 'date': 'Aug 30, 2021', 'snippet': 'Octapharma USA announced the FDA has awarded seven years of marketing \nexclusivity for Octagam® 10%, the only IVIg indicated for adult...', 'thumbnail': 'https://serpapi.com/searches/672319740be2f63ada2a4ea3/images/7bdf924c9fe6c8f24b4d3806d6f990e1422e8624d1738a95b512712b4426f217.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.564315915107727}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04120116,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1002/pat.6193?af=R', 'title': 'Advances in injectable hydrogel: Design, functional regulation, and biomedical applications', 'source': 'Wiley Online Library', 'date': 'Oct 2, 2023', 'snippet': 'Recently, injectable hydrogels have been considered smart materials and \nhave been widely researched for their use as scaffolds.', 'thumbnail': 'https://serpapi.com/searches/6723198a3c944b0711a2effb/images/0843c57872eb5fb87cc918028dd3df6bdc85b8af11db9d71714982816fd6c07e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5245862603187561}",,,,,,,,,,['positive'],positive,1 NCT05304611,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/experimental-nih-malaria-monoclonal-antibody-protective-malian-children', 'title': 'Experimental NIH malaria monoclonal antibody protective in Malian children', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Apr 26, 2024', 'snippet': 'Mid-stage trial shows treatment prevents infection, disease.', 'thumbnail': 'https://serpapi.com/searches/67231991b4fe87d275d35925/images/dc387c04aa31da3fc0c0f1a536c44c828af4d613c8635c7f6bc0966a17b4af2a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8246906995773315}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2312775', 'title': 'Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria', 'source': 'The New England Journal of Medicine', 'date': 'Apr 26, 2024', 'snippet': 'Subcutaneous administration of the monoclonal antibody L9LS protected \nadults against controlled Plasmodium falciparum infection in a phase 1...', 'thumbnail': 'https://serpapi.com/searches/67231991b4fe87d275d35925/images/dc387c04aa31da3f78c32ce057f046e04b931508469396aca3a733422c0ffff5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8696849346160889}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01667536,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/58/9/1408', 'title': 'Phase 2 Study of 99mTc-Trofolastat SPECT/CT to Identify and Localize Prostate Cancer in Intermediate- and High-Risk Patients Undergoing Radical Prostatectomy and Extended Pelvic LN Dissection', 'source': 'Journal of Nuclear Medicine', 'date': 'Sep 1, 2017', 'snippet': '99m Tc-trofolastat SPECT/CT detects PCa with high sensitivity in patients \nwith intermediate- and high-risk PCa compared with histology.', 'thumbnail': 'https://serpapi.com/searches/6723199993584c270e7ba4a3/images/4572fe181e012eceb52b6d9479c756648e17fc8b84642a7bd5466aaff053ab23.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8805703520774841}",,,,,,,,,,['neutral'],neutral,1 NCT04984356,"{'position': 1, 'link': 'https://www.cgtlive.com/view/news-cell-therapy-rare-cancer-day-2024', 'title': 'News in Cell and Gene Therapy for Rare Cancer Day 2024', 'source': 'CGTLive®', 'date': '1 month ago', 'snippet': ""In observance of Rare Cancer Day, held annually on September 30, catch up \non the past few months' news related to gene and cell therapies in..."", 'thumbnail': 'https://serpapi.com/searches/672318c15c7cb9ea52f8677b/images/891781de514dd81d64164fb0656fd6983c40a53c5c60b2eabdc84f94890720c4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8710896372795105}",,,,,,,,,,['neutral'],neutral,1 NCT02378480,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1800170', 'title': 'Omadacycline for Acute Bacterial Skin and Skin-Structure Infections', 'source': 'The New England Journal of Medicine', 'date': 'Feb 6, 2019', 'snippet': 'Omadacycline was noninferior to linezolid for the treatment of acute \nbacterial skin and skin-structure infections and had a similar safety \nprofile.', 'thumbnail': 'https://serpapi.com/searches/672318cc642c31fec49d7aa3/images/7ff4d8bc4774be61ba7f9d45aba1c933aaf94641faac6bd75b4fb074a764c9b6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8277717232704163}",,,,,,,,,,['neutral'],neutral,1 NCT05277350,"{'position': 1, 'link': 'https://www.nature.com/articles/s41587-023-01759-y', 'title': 'Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice', 'source': 'Nature', 'date': 'May 4, 2023', 'snippet': 'Antibiotic treatments have detrimental effects on the microbiome and lead \nto antibiotic resistance. To develop a phage therapy against a...', 'thumbnail': 'https://serpapi.com/searches/672318d6213c87b971b47242/images/db765d9898739e17fce5b70f8b82d3967aeabc41bec949ae290ec35c532b76ed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5392537117004395}",,,,,,,,,,['neutral'],neutral,1 NCT04469621,"{'position': 1, 'link': 'https://www.genengnews.com/news/sanofi-and-denali-therapeutics-sar443122-dnl758/', 'title': 'Sanofi and Denali Therapeutics – SAR443122 (DNL758)', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Sep 8, 2020', 'snippet': 'Small molecule inhibitor of RIPK1 that does not cross the blood-brain \nbarrier, and is in development for patients with peripheral inflammatory \ndiseases.', 'thumbnail': 'https://serpapi.com/searches/672318f0ef60cb338d94d255/images/a8721252d31508df6ac0768d6f61171f3dfa10187ae2d4bdc95a2a119bc3bea3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.816842794418335}",,,,,,,,,,['neutral'],neutral,1 NCT02982941,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Trials-including-patients-with-desmoplastic-small-round-cell-tumor_tbl1_340814307', 'title': 'Trials including patients with desmoplastic small round cell tumor.', 'source': 'ResearchGate', 'date': 'May 2, 2020', 'snippet': 'Desmoplastic small round cell tumor (DSRCT) is a devastating disease which \nmost commonly affects adolescents, with a male predominance.', 'thumbnail': 'https://serpapi.com/searches/672319017f3719c39a63881f/images/5b4be3aebf3bcfcf68a2d95714808b209d5bd5539544842ff61259f72e7715bc.png', 'sentiment': 'negative', 'sentiment_prob': 0.8475664854049683}",,,,,,,,,,['negative'],negative,0 NCT00883129,"{'position': 1, 'link': 'https://sclerodermanews.com/news/study-confirms-mmf-is-effective-treatment-for-scleroderma-related-lung-disease/', 'title': 'Scleroderma-related Lung Disease Study Confirms MMF Is Effective Therapy', 'source': 'Scleroderma News', 'date': 'Sep 14, 2017', 'snippet': 'Read about a study confirming that mycophenolate mofetil is an effective \ntreatment for people with scleroderma-related lung disease.', 'thumbnail': 'https://serpapi.com/searches/67231906b691a72daec1b893/images/5386e494a12633c8686dddf8c1fca4a6296f9f8d2e8d10e35fff19347f95ade8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5428546667098999}",,,,,,,,,,['neutral'],neutral,1 NCT02802345,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1811737', 'title': 'Nintedanib plus Sildenafil in Patients with Idiopathic Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 15, 2018', 'snippet': 'Nintedanib is an approved treatment for idiopathic pulmonary fibrosis \n(IPF). A subgroup analysis of a previously published trial suggested...', 'thumbnail': 'https://serpapi.com/searches/672319ead11a89a65f48af4a/images/aaf97825665861be782eb1ecb21854c6ad57cf2004b05e4d7faa55c2dd20785f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8332849740982056}",,,,,,,,,,['neutral'],neutral,1 NCT03057951,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2107038', 'title': 'Empagliflozin in Heart Failure with a Preserved Ejection Fraction', 'source': 'The New England Journal of Medicine', 'date': 'Aug 27, 2021', 'snippet': 'In this double-blind trial, we randomly assigned 5988 patients with class \nII–IV heart failure and an ejection fraction of more than 40% to receive...', 'thumbnail': 'https://serpapi.com/searches/672319f390adce4aba20bc34/images/fa5a87c827aa39f92a21bc985fe4a3cacce59707ebc5f6c7aabe33c32aac1318.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.727074146270752}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.057812', 'title': 'Empagliflozin, Health Status, and Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 15, 2021', 'snippet': 'Background:Patients with heart failure with preserved ejection fraction \nhave significant impairment in health-related quality of life.', 'thumbnail': 'https://serpapi.com/searches/672319f390adce4aba20bc34/images/fa5a87c827aa39f925b052083547ac2744373319a44f9d0923eb340db5b82d8c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8105812668800354}","{'position': 3, 'link': 'https://www.researchgate.net/figure/The-trial-design-and-key-outcome-measures-from-the-DELIVER-study-Figure-adapted-from_fig2_343918465', 'title': 'Fig. 2 The trial design and key outcome measures from the DELIVER...', 'source': 'ResearchGate', 'date': 'Nov 23, 2020', 'snippet': 'DELIVER trial is a phase III international, multicentre, parallel-group, \nrandomised, Table 2 and the study design is presented in Fig.', 'thumbnail': 'https://serpapi.com/searches/672319f390adce4aba20bc34/images/fa5a87c827aa39f9c8b783f064d571cbd4bad0bdcac355a9cae6c6c94f5e361c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9150642156600952}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04927221,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S1550413122000948', 'title': 'Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial', 'source': 'ScienceDirect.com', 'date': 'May 3, 2022', 'snippet': 'We report the discovery of DC371739, an indole-containing \ntetrahydroisoquinoline compound with promising lipid-lowering effects, both \nin vitro and in vivo, and...', 'thumbnail': 'https://serpapi.com/searches/67231a02b2ebae6228945e63/images/44c5c4a4756925bc261722fce3a731f379ab82e9f939c1051d9cf554e271c57e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5752447843551636}",,,,,,,,,,['positive'],positive,1 NCT04667377,"{'position': 1, 'link': 'https://www.patientcareonline.com/view/survodutide-novel-gcgr-glp-1ra-shows-promise-in-obesity-mash-treatment', 'title': 'Survodutide: Novel GCGR/GLP-1RA Shows Promise in Obesity, MASH Treatment', 'source': 'Patient Care Online', 'date': '1 month ago', 'snippet': 'New data presented at the 60th Annual Meeting of the European Association \nfor the Study of Diabetes (EASD) 2024 showed survodutide...', 'thumbnail': 'https://serpapi.com/searches/67231a18dc969f1f5a2fdd0a/images/6755ec5efb0529727c71b34884a6bb604daad29ec2922c4bcd78393e7ddcb3cc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6515651941299438}",,,,,,,,,,['neutral'],neutral,1 NCT03104699,"{'position': 1, 'link': 'https://cervicalcancernews.com/2017/04/24/clinical-trial-agenus-new-therapy-cervical-cancer-solid-tumors/', 'title': 'Agenus Begins Clinical Trial Testing New Therapy for Cervical Cancer, Solid Tumors', 'source': 'Cervical cancer News', 'date': 'Apr 24, 2017', 'snippet': ""The first patient has been dosed in the Phase 1/2 trial testing AGEN2034, \nAgenus' new PD-1 inhibitor, in patients with advanced solid tumors and \ncervical..."", 'thumbnail': 'https://serpapi.com/searches/67231a322e33c8a63dec0975/images/e63c53d3e8d110848fd0a7b737fdd9368ef0bc12d921570574f841ca42b183b4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9088606834411621}",,,,,,,,,,['neutral'],neutral,1 NCT02686658,"{'position': 1, 'link': 'https://www.nature.com/articles/s41433-023-02497-w', 'title': 'Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial', 'source': 'Nature', 'date': 'Mar 24, 2023', 'snippet': 'Over this 18-month study, ACP 2 mg and 4 mg showed continued reductions in \nthe progression of GA growth compared to sham and continued to be generally \nwell...', 'thumbnail': 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'https://www.empr.com/home/news/izervay-approved-for-geographic-atrophy-secondary-to-amd/', 'title': 'Izervay Approved for Geographic Atrophy Secondary to AMD', 'source': 'Medical Professionals Reference', 'date': 'Aug 7, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Izervay™ (avacincaptad \npegol intravitreal solution) for the treatment of geographic...', 'thumbnail': 'https://serpapi.com/searches/67231a7b749783416cf42082/images/50822c1ec399bde77e43fa5d3c9756a19700a59ee330d63d1862f081e23d3476.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7763739824295044}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT00632866,"{'position': 1, 'link': 'https://sjogrenssyndromenews.com/news/sjogrens-symptoms-not-affected-by-seasonal-changes-study-finds/', 'title': 'Sjögren’s Symptoms Not Affected by Seasonal Changes, Study Finds', 'source': ""Sjogren's Syndrome News"", 'date': 'Apr 8, 2020', 'snippet': ""Seasonal changes do not appear to influence the main symptoms of primary \nSjögren's syndrome — pain, fatigue, and dryness — according to a..."", 'thumbnail': 'https://serpapi.com/searches/67231a9ea86921c141714a6e/images/c73f645a2df627bbf7b98faa09c5f5d028747b513075a77cdf6abf3e567fef41.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8096309900283813}","{'position': 2, 'link': 'https://sjogrenssyndromenews.com/news/sjogrens-can-be-classified-in-four-subgroups-depending-on-symptoms-study-suggests/', 'title': 'Sjögren’s Patients Fall into 4 Distinct Groups Depending on Symptoms, Study Suggests', 'source': ""Sjogren's Syndrome News"", 'date': 'Jan 2, 2020', 'snippet': ""People with Sjögren's syndrome may be classified into four groups based on \nsymptoms, each possibly with a distinct disease biology and..."", 'thumbnail': 'https://serpapi.com/searches/67231a9ea86921c141714a6e/images/c73f645a2df627bb9c631ce908e9f9f006b0bc82484415fa94817ca5a40a0ab1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6786310076713562}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02485704,"{'position': 1, 'link': 'https://www.empr.com/home/news/natroba-spinosad-topical-suspension-scabies-infestations/', 'title': 'Natroba Topical Suspension Approved for Scabies Treatment', 'source': 'Medical Professionals Reference', 'date': 'Apr 29, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Natroba TM (spinosad) \ntopical suspension for the treatment of scabies infestations in patients 4 \nyears of...', 'thumbnail': 'https://serpapi.com/searches/67231aaee281ee018cee3d21/images/75d119db06fdb8119aa3fcb6bb167088f5abb538f4d1dc13bf85b11a4fde6cb9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8773550987243652}",,,,,,,,,,['neutral'],neutral,1 NCT01011868,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/jcpt.13521', 'title': 'Efficacy and safety of empagliflozin at different doses in patients with type 2 diabetes mellitus: A network meta-analysis based on randomized controlled trials', 'source': 'Wiley Online Library', 'date': 'Sep 20, 2021', 'snippet': 'As an oral hypoglycaemic drug that significantly reduces cardiovascular \nrisk, empagliflozin is often used in patients with type 2 diabetes...', 'thumbnail': 'https://serpapi.com/searches/67231ab772f716bb6101ca49/images/362394ba0cc8b5f700d352bace8ebb679c6a338b0e72df3649d96f06e0f1723e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.867742657661438}",,,,,,,,,,['neutral'],neutral,1 NCT02332499,"{'position': 1, 'link': 'https://www.nature.com/articles/aps2017199', 'title': 'Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species', 'source': 'Nature', 'date': 'Apr 5, 2018', 'snippet': 'Anlotinib is a new oral tyrosine kinase inhibitor; this study was designed \nto characterize its pharmacokinetics and disposition.', 'thumbnail': 'https://serpapi.com/searches/67231abbd364b47823e1b023/images/eecbace0949d509e36517aee4f98ce74f1b4175a86eda90a123afdeb89f556aa.jpeg', 'sentiment': 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'snippet': 'Topline results from the phase 3 COMMAND trial (NCT03682536) indicated that \nthe use of luspatercept-aamt (Reblozyl) for treating adult...', 'thumbnail': 'https://serpapi.com/searches/67231b01b28e6bea4b5b55e2/images/3d4e0b2a8bc5392347fbeba456b253fcfc0d4c9527beb62f3d5b0f66d7f7d49c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5078725218772888}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT03178032,"{'position': 1, 'link': 'https://www.nejm.org/doi/abs/10.1056/NEJMoa2202028', 'title': 'Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma', 'source': 'The New England Journal of Medicine', 'date': 'Jun 29, 2022', 'snippet': 'We conducted a single-center, dose-escalation study of DNX-2401, an \noncolytic adenovirus that selectively replicates in tumor cells, in \npatients with newly...', 'thumbnail': 'https://serpapi.com/searches/67231b3075f974afac1148b5/images/37061444b86f1c96d5a7638c4170e2374d0be079574a0320bd47d2a816be13ca.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7948493361473083}",,,,,,,,,,['neutral'],neutral,1 NCT03387137,"{'position': 1, 'link': 'https://www.canada.ca/en/public-health/services/reports-publications/canada-communicable-disease-report-ccdr/monthly-issue/2020-46/issue-4-april-2-2020/article-1-challenges-developing-vaccine-respiratory-syncytial-virus.html', 'title': 'Overview of the respiratory syncytial virus vaccine candidate pipeline in Canada, CCDR 46(4)', 'source': 'Canada.ca', 'date': 'Apr 2, 2020', 'snippet': 'A vaccine for respiratory syncytial virus (RSV) has been actively sought \nfor over 60 years due to the health impacts of RSV disease in infants.', 'thumbnail': 'https://serpapi.com/searches/67231b3df6aa53bdf3526bf6/images/e2ba98a550bab50e51de90f01b4c3540e76f67d564da39416582c714d680702c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.867176353931427}",,,,,,,,,,['neutral'],neutral,1 NCT04280705,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2007764', 'title': 'Remdesivir for the Treatment of Covid-19 — Final Report', 'source': 'The New England Journal of Medicine', 'date': 'May 22, 2020', 'snippet': 'Our data show that remdesivir was superior to placebo in shortening the \ntime to recovery in adults who were hospitalized with Covid-19 and had \nevidence of...', 'thumbnail': 'https://serpapi.com/searches/67231b41a54d7e5ab852835d/images/cd3a8dfe27833d94db850a57ad7e44bf29c7fa7777c6d7281cdad9cbdbdc6dc8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6877774000167847}","{'position': 2, 'link': 'https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins', 'title': 'NIH clinical trial of remdesivir to treat COVID-19 begins', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Feb 25, 2020', 'snippet': 'A randomized, controlled clinical trial to evaluate the safety and efficacy \nof the investigational antiviral remdesivir in hospitalized adults \ndiagnosed with...', 'thumbnail': 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'https://www.infectiousdiseaseadvisor.com/news/10-day-course-of-remdesivir-shorten-time-to-recovery-in-coronavirus-patients/', 'title': 'Remdesivir Superior to Placebo in Hospitalized Patients With COVID-19', 'source': 'Infectious Disease Advisor', 'date': 'Nov 25, 2020', 'snippet': 'A 10-day course of remdesivir was superior to placebo in shortening the \ntime to recovery in hospitalized patients with coronavirus disease 2019 \n(COVID-19).', 'thumbnail': 'https://serpapi.com/searches/67231b41a54d7e5ab852835d/images/cd3a8dfe27833d9463188772cdc105138dd1420ce7206068bcf4253e284b63f7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7959307432174683}","{'position': 5, 'link': 'https://leadstories.com/hoax-alert/2020/05/fact-check-hydrochloroquine-not-a-vaccine-being-held-back-and-studies-are-underway-for-drugs-that-will-not-be-immediately-injected-into-people.html', 'title': 'Fact Check: Hydroxychloroquine is NOT A Drug Being Held Back, And Studies ARE Underway For Vaccines That Will NOT Be Immediately Injected in People.', 'source': 'leadstories.com', 'date': 'May 2, 2020', 'snippet': 'Is it true that ""thousands of doctors"" say hydroxychloroquine ""cures"" \nCOVID-19 patients,"" but the cure won\'t be valid until a...', 'thumbnail': 'https://serpapi.com/searches/67231b41a54d7e5ab852835d/images/cd3a8dfe27833d94e055d80893b79d83a44d08f4dabd80c6934989778c1f49f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7088871598243713}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04165824,"{'position': 1, 'link': 'https://alsnewstoday.com/news/radicava-prolongs-survival-als-patients-study-japan/', 'title': 'Radicava Prolongs Survival in ALS Patients, Study from Japan Indicates', 'source': 'ALS News Today', 'date': 'Aug 18, 2021', 'snippet': 'Long-term treatment with Radicava (edaravone) is generally safe and nearly \ndoubles survival time in adults with amyotrophic lateral...', 'thumbnail': 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'source': 'The Lancet', 'date': 'Mar 9, 2016', 'snippet': 'Outcomes are poor for patients with previously treated, advanced or \nmetastatic non-small-cell lung cancer (NSCLC). The anti-programmed death...', 'thumbnail': 'https://serpapi.com/searches/67231ca9efad2193710cc197/images/389582f1cff1e55360e8c424f122867d60789bc902d33841cd40e2be9df261d2.png', 'sentiment': 'negative', 'sentiment_prob': 0.6142983436584473}","{'position': 2, 'link': 'https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05509-9', 'title': 'Integrating knowledge graphs into machine learning models for survival prediction and biomarker discovery in patients with non–small-cell lung cancer', 'source': 'Journal of Translational Medicine', 'date': 'Aug 5, 2024', 'snippet': 'Accurate survival prediction for Non-Small Cell Lung Cancer (NSCLC) \npatients remains a significant challenge for the scientific and clinical...', 'thumbnail': 'https://serpapi.com/searches/67231ca9efad2193710cc197/images/389582f1cff1e5530118766f2c3db7c0b61afa48b54b5731a0807017d0364d9f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7933346629142761}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT02943785,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2111016', 'title': 'Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR', 'source': 'The New England Journal of Medicine', 'date': 'Aug 28, 2021', 'snippet': 'The role of direct oral anticoagulants as compared with vitamin K \nantagonists for atrial fibrillation after successful transcatheter...', 'thumbnail': 'https://serpapi.com/searches/67231cbc23a4b50b0bc021f5/images/b2d57f173e2268af472debd206a91ee959632919480f2a4a7c3c7cb91b84a55c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9063099026679993}",,,,,,,,,,['neutral'],neutral,1 NCT02301039,"{'position': 1, 'link': 'https://www.targetedonc.com/view/sarcoma-awareness-month-impact-of-molecular-testing-and-individualized-treatments', 'title': 'Sarcoma Awareness Month: Impact of Molecular Testing and Individualized Treatments', 'source': 'Targeted Oncology', 'date': 'Jul 19, 2023', 'snippet': 'For Sarcoma Awareness Month, Lisa B. 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This \ntrial compared the protective efficacy in older adults of a...', 'thumbnail': 'https://serpapi.com/searches/67239f4a3d629bbc1df0d679/images/74e2d41bb85c406f1c446deb6e8206af280603e6c371035c0a764eb9a89b5ddf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8649623394012451}",,,,,,,,,,['neutral'],neutral,1 NCT01810705,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.807266/full', 'title': 'Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells', 'source': 'Frontiers', 'date': 'Jun 27, 2023', 'snippet': 'Despite intensive chemotherapy regimens, up to 60% of adults with acute \nmyeloid leukaemia (AML) will relapse and eventually succumb to their \ndisease.', 'thumbnail': 'https://serpapi.com/searches/6723a1130f1a33123715b955/images/7187e325b7727d878e31ef7cc8780a6497f9977a1c7365542d1b696dca0e2a70.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'Read about a study reporting that a combination of Pomalyst and \ndexamethasone is a more cost-effective therapy for myeloma than Kyprolis \nor...', 'thumbnail': 'https://serpapi.com/searches/6723a137adc33b91195e3858/images/8bbf8332ec5434510a5b8af2b6adcfcbbb695f495222693d138c05f9292d78c8.png', 'sentiment': 'positive', 'sentiment_prob': 0.5470622777938843}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02516553,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-01815-5', 'title': 'Therapeutic impact of BET inhibitor BI 894999 treatment: backtranslation from the clinic', 'source': 'Nature', 'date': 'Apr 20, 2022', 'snippet': 'BET inhibitors have been tested in several clinical trials where, despite \nencouraging preclinical results, substantial clinical benefit in...', 'thumbnail': 'https://serpapi.com/searches/6723a37498721711d1e0bc32/images/9bbce920f65f669f0eee1635424e79a95f0b8710f5824a20419e961c10fc64b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Institute of Regenerative Medicine (AIRM), and \nits...', 'thumbnail': 'https://serpapi.com/searches/6723a6802b5fa7f3c396d07e/images/d68c47bb5ed00b9f8a70b0dc585526bb1b80f25fbf941211baf2f02a1538422c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9050300717353821}",,,,,,,,,,['neutral'],neutral,1 NCT04625725,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2116620', 'title': 'Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Apr 20, 2022', 'snippet': 'The monoclonal-antibody combination AZD7442 is composed of tixagevimab and \ncilgavimab, two neutralizing antibodies against severe acute...', 'thumbnail': 'https://serpapi.com/searches/6723acdef41044934315b4fa/images/79eec1284dc1c4ee64a135b06858be0b99f8d43211d6a17e48e55b90c8802845.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8653955459594727}",,,,,,,,,,['neutral'],neutral,1 NCT04575259,"{'position': 1, 'link': 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2021', 'snippet': 'A conditionally replication-defective human cytomegalovirus (HCMV) vaccine, \nV160, was shown to be safe and immunogenic in a two-part, double-blind, \nrandomized,...', 'thumbnail': 'https://serpapi.com/searches/6723b6e8e95dbfe0bbe48d92/images/e17b65496add6c7cb97fe7b34b80712ecaa9e5baf0edab046ee188a7b2a36aea.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7006304860115051}",,,,,,,,,,['neutral'],neutral,1 NCT04231968,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45241-y', 'title': 'Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor', 'source': 'Nature', 'date': 'Feb 8, 2024', 'snippet': 'Respiratory syncytial virus (RSV) is a common cause of acute lower \nrespiratory tract infection in infants, older adults and the...', 'thumbnail': 'https://serpapi.com/searches/6723afe54a3fcf8116858f78/images/4b338b68b8d481d75189caf5ce8cae606fb5207d3b74a7bc54d717a7e36a4b38.jpeg', 'sentiment': 'negative', 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'source': 'Nature', 'date': 'Jul 11, 2019', 'snippet': 'The purpose of this study was to determine the accuracy of DXA at detecting \nchanges in lean mass, using MRI-derived MV as a reference standard.', 'thumbnail': 'https://serpapi.com/searches/6723b1b9a775f2fae9822aef/images/5b9ed27a7179d3ac047577782668edb6703a7990df2c578b9f41a2ce5774737d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8964696526527405}",,,,,,,,,,['neutral'],neutral,1 NCT00467779,"{'position': 1, 'link': 'https://www.nature.com/articles/bjc201710', 'title': 'A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor', 'source': 'Nature', 'date': 'Feb 2, 2017', 'snippet': 'Binimetinib (MEK162; ARRY-438162) is a potent and selective oral MEK 1/2 \ninhibitor. 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A \ntotal of 38 patients with TS were assigned to the control group...', 'thumbnail': 'https://serpapi.com/searches/6723b5087f3719caf9b46c2d/images/d5b1f691716f0f966a49b3f17dfb753667a47e1ea3640afe62852493e43a5e09.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8454774022102356}",,,,,,,,,,['neutral'],neutral,1 NCT02528214,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1804093', 'title': 'Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma', 'source': 'The New England Journal of Medicine', 'date': 'May 21, 2018', 'snippet': 'Dupilumab treatment has been shown to reduce the rate of exacerbations and \nimprove lung function in patients with uncontrolled moderate-to-severe \nasthma.', 'thumbnail': 'https://serpapi.com/searches/6723b5dafda26da806ff0b7c/images/d498be2707b87a41ca8f6e745e7c345db96e1ffd1150d01f591a553133a9e085.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6738165020942688}",,,,,,,,,,['neutral'],neutral,1 NCT02493361,"{'position': 1, 'link': 'https://melanomanewstoday.com/2017/05/16/immunopulse-il-12-keytruda-combo-therapy-phase-2-trial/', 'title': 'ImmunoPulse IL-12 and Keytruda Combo Therapy to be Tested in Phase 2 Trial', 'source': 'Melanoma News Today', 'date': 'May 16, 2017', 'snippet': 'Learn more about the Phase 2 trial to be conducted by OncoSec in \ncollaboration with Merck, testing the efficacy of ImmunoPulse IL-12,...', 'thumbnail': 'https://serpapi.com/searches/6723b6042a488234547b502c/images/4d8a5287fbaf9fe35d39c792b1ad760eab1a62d9d67a8f9cf8ac6889da0d54a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9118946194648743}",,,,,,,,,,['neutral'],neutral,1 NCT02614612,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1111/bjh.18300', 'title': 'A biomarker signature to predict complete response to itacitinib and corticosteroids in acute graft-versus-host disease', 'source': 'Wiley Online Library', 'date': 'Jun 11, 2022', 'snippet': 'An official journal of the British Society for Haematology, the British \nJournal of Haematology offers high visibility for clinical,...', 'thumbnail': 'https://serpapi.com/searches/6723b60a81bab78d989153b2/images/2e927927eee1b0f6428f0995de0df59b0374311b45ba12587e298fbb985ede15.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8829355239868164}",,,,,,,,,,['neutral'],neutral,1 NCT02697734,"{'position': 1, 'link': 'https://cushingsdiseasenews.com/news/isturisa-found-safe-effective-cushings-long-term-trial-extension/', 'title': 'Isturisa found to be safe, effective in long-term trial extension', 'source': ""Cushing's Disease News"", 'date': 'Aug 25, 2023', 'snippet': 'Long-term treatment with Isturisa (osilodrostat) led to a sustained \nnormalization in cortisol levels, symptom relief, and improved quality of \nlife for people...', 'thumbnail': 'https://serpapi.com/searches/6723b67c0a545ab58bdb9bf1/images/5fa166bc06cbf07d4115e0979c7473ffa78763aec48a7f08d45a86e787317db6.png', 'sentiment': 'positive', 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Treatment Plan Changed Following Fluciclovine 18F PET/CT"", 'source': 'Imaging Technology News', 'date': 'Oct 4, 2017', 'snippet': 'Results presented at 2017 ASTRO Annual Meeting evaluate clinical utility of \nfluciclovine (18F) PET/CT imaging in men with recurrent prostate...', 'thumbnail': 'https://serpapi.com/searches/6723b6f564f11dda37af0411/images/de228a505701079f8cfa6cbcb183521e05be1bcf36a176164684ac57a71b7258.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8590338230133057}","{'position': 2, 'link': 'https://www.itnonline.com/content/falcon-trial-fluciclovine-petct-imaging-stops-recruitment-after-successful-interim-analysis', 'title': 'FALCON Trial of Fluciclovine PET/CT Imaging Stops Recruitment After Successful Interim Analysis', 'source': 'Imaging Technology News', 'date': 'May 15, 2017', 'snippet': 'Study evaluates clinical utility of fluciclovine (18F) PET/CT imaging in \nmen with recurrent prostate cancer following prior treatment.', 'thumbnail': 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'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1329426/full', 'title': 'Clinical research on RSV prevention in children and pregnant women: progress and perspectives', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': 'This review provides a comprehensive summary of RSV monoclonal antibody \n(mAb) and vaccine clinical trials registered on ClinicalTrials.gov', 'thumbnail': 'https://serpapi.com/searches/6723b7cc2a7727c0d914d6e9/images/6b0c8115f5daaa43acf9ef648143572cd678a2bb90141c4a1dbfdea3f5ca1c72.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8756221532821655}",,,,,,,,,,['neutral'],neutral,1 NCT03418090,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-xenoview-for-evaluating-lung-ventilation/', 'title': 'FDA Approves Xenoview for Evaluating Lung Ventilation', 'source': 'Medical Professionals Reference', 'date': 'Dec 29, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Xenoview™ (xenon Xe 129 \nhyperpolarized), a hyperpolarized contrast agent indicated for...', 'thumbnail': 'https://serpapi.com/searches/6723b829b9458db2487eced5/images/d3decdb20c23eeb903c4e760c43e8f3f7d65330f2e10ea9c608777e36916b128.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7300285696983337}",,,,,,,,,,['neutral'],neutral,1 NCT00852423,"{'position': 1, 'link': 'https://www.researchgate.net/publication/383703770_Population_pharmacokinetics_of_amodiaquine_and_piperaquine_in_African_pregnant_women_with_uncomplicated_Plasmodium_falciparum_infections', 'title': '(PDF) Population pharmacokinetics of amodiaquine and piperaquine in African pregnant women with uncomplicated Plasmodium falciparum infections', 'source': 'ResearchGate', 'date': 'Sep 4, 2024', 'snippet': 'This study aimed to evaluate the PK properties of amodiaquine and its \nactive metabolite, desethylamodiaquine, and piperaquine in women in their \nsecond and...', 'thumbnail': 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'https://www.nature.com/articles/s41698-021-00232-w', 'title': 'Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies', 'source': 'Nature', 'date': 'Oct 19, 2021', 'snippet': 'In a pilot study, we evaluated the feasibility of real-time deep analysis \nof serial tumor samples from triple negative breast cancer patients.', 'thumbnail': 'https://serpapi.com/searches/6723b9ae657c66ad86b29c20/images/2a8b5b94d0e2180ec57071fa4446e84935bda88d880e26120d45b20a43d8e652.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8951044082641602}",,,,,,,,,,['neutral'],neutral,1 NCT01593696,"{'position': 1, 'link': 'https://www.onclive.com/view/tisa-cel-reinfusion-shows-potential-as-hsct-bridging-therapy-in-pediatric-b-all', 'title': 'Tisa-cel Reinfusion Shows Potential as HSCT Bridging Therapy in Pediatric B-ALL', 'source': 'OncLive', 'date': 'Feb 19, 2023', 'snippet': 'Second infusion with tisagenlecleucel after prior tisagenlecleucel infusion \nproduced short durations of minimal residual disease-negative...', 'thumbnail': 'https://serpapi.com/searches/6723b9c8be80139b2f173fcf/images/ec3d31d258f58991d5dcae278c65acb2911967ae0e44cde279bff703b3ec4834.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7540166974067688}",,,,,,,,,,['neutral'],neutral,1 NCT03986138,"{'position': 1, 'link': 'https://www.empr.com/home/news/gadopiclenol-a-new-macrocyclic-gadolinium-based-contrast-agent-gets-fda-approval/', 'title': 'Gadopiclenol, a New Macrocyclic Gadolinium-Based Contrast Agent, Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Sep 22, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved 2 new macrocyclic \ngadolinium-based contrast agents (GBCAs), Elucirem™ (gadopiclenol) and...', 'thumbnail': 'https://serpapi.com/searches/6723b9d2fc183d2d1bec010b/images/c0593d9565db63ae5d34ab12f901968b7c1697205929bc010befe2c8feef1951.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5789949893951416}",,,,,,,,,,['positive'],positive,1 NCT04401579,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2031994', 'title': 'Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Dec 11, 2020', 'snippet': 'Baricitinib plus remdesivir was superior to remdesivir alone in reducing \nrecovery time and accelerating improvement in clinical status among \npatients with...', 'thumbnail': 'https://serpapi.com/searches/6723b889b6ed33ddf7931879/images/1204dd23a4d473fc16b49e8af6492fccf9286e4d2068fa90bbc28a60cc96fead.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6585750579833984}","{'position': 2, 'link': 'https://www.conservativewoman.co.uk/remdesivir-papers-allege-controversial-drug-used-to-treat-service-members-led-to-601-deaths/', 'title': 'Lethal drug given to US service personnel – and hundreds died', 'source': 'The Conservative Woman', 'date': '2 weeks ago', 'snippet': 'A MILITARY whistleblower has released a series of documents revealing 601 \ndeaths of service personnel and a high rate of serious adverse...', 'thumbnail': 'https://serpapi.com/searches/6723b889b6ed33ddf7931879/images/1204dd23a4d473fc8822d82c945be05cf1af85bf654b90569122ded00a244d5d.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8413755893707275}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT03677934,"{'position': 1, 'link': 'https://www.optometrytimes.com/view/what-s-hot-and-not-in-retinal-news', 'title': 'What’s hot (and not) in retinal news', 'source': 'Optometry Times', 'date': 'May 12, 2022', 'snippet': 'A look at the latest developments in retinal disease, including clinical \ntrials and advanced therapies.', 'thumbnail': 'https://serpapi.com/searches/6723b88b98721769691ba202/images/7867b719df09571c74b0305fd746de531faa8ec4efe2ffc53d4d9d142f6d9472.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8849452137947083}",,,,,,,,,,['neutral'],neutral,1 NCT05579691,"{'position': 1, 'link': 'https://friedreichsataxianews.com/news/fda-lifts-partial-clinical-hold-nomlabofusp-friedreichs-ataxia/', 'title': 'Partial clinical hold on nomlabofusp for Friedreich’s ataxia lifted', 'source': ""Friedreich's Ataxia News"", 'date': 'May 28, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has removed the partial hold on \nthe clinical development of nomlabofusp, an experimental treatment for \nFriedreich's..."", 'thumbnail': 'https://serpapi.com/searches/6723b9906aa3644f4ad2ecab/images/3710c96b313c16688a1036f9774d8d8e061745a7def4e116530abb53f6b4de8f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9237340092658997}","{'position': 2, 'link': 'https://friedreichsataxianews.com/news/cti-1601-high-dose-safely-raises-frataxin-fa-clinical-trial/', 'title': 'CTI-1601 at high dose safely raises frataxin levels in FA clinical trial', 'source': ""Friedreich's Ataxia News"", 'date': 'Feb 21, 2024', 'snippet': 'Daily treatment with CTI-1601, now nomlabofusp, at 50 mg dose was safe, \nwith higher frataxin levels in cells of patients in Phase 2 trial.', 'thumbnail': 'https://serpapi.com/searches/6723b9906aa3644f4ad2ecab/images/3710c96b313c16689f60c0df0fd1041e79657360d685a29a9e6c7bf18c9da3f6.png', 'sentiment': 'positive', 'sentiment_prob': 0.5327481031417847}","{'position': 3, 'link': 'https://friedreichsataxianews.com/news/higher-dose-fa-treatment-cti-1601-ole-study-win-fda-clearance/', 'title': 'Higher dose of FA treatment CTI-1601, OLE study win FDA clearance...', 'source': ""Friedreich's Ataxia News"", 'date': 'Aug 1, 2023', 'snippet': ""The US Food and Drug Administration (FDA) has greenlighted a request by \nLarimar Therapeutics to test a 50 mg dose of CTI-1601 on people with \nFriedreich's..."", 'thumbnail': 'https://serpapi.com/searches/6723b9906aa3644f4ad2ecab/images/3710c96b313c1668fc18e21285d99f4535495f9141476699daa8831386527068.png', 'sentiment': 'neutral', 'sentiment_prob': 0.627572774887085}","{'position': 4, 'link': 'https://friedreichsataxianews.com/news/first-friedreichs-ataxia-patient-dosed-ole-study-nomlabofusp/', 'title': 'First FA patient dosed in OLE study of nomlabofusp, formerly CTI-1601', 'source': ""Friedreich's Ataxia News"", 'date': 'Mar 19, 2024', 'snippet': 'The first patient has been dosed in a long-term, open-label extension (OLE) \nof a Phase 2 dose escalation study that tested nomlabofusp, formerly \nCTI-1601.', 'thumbnail': 'https://serpapi.com/searches/6723b9906aa3644f4ad2ecab/images/3710c96b313c166838ba9a9130c1c9f05e95250d3bcce17512ff52710d19ddc8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8837335109710693}","{'position': 5, 'link': 'https://friedreichsataxianews.com/friedreichs-ataxia-experimental-treatments/cti-1601/', 'title': ""CTI-1601 for Friedreich's ataxia"", 'source': ""Friedreich's Ataxia News"", 'date': 'Aug 15, 2017', 'snippet': 'Nomlabofusp, also known as CTI-1601, is a potential FA therapy by Larimar \nTherapeutics designed to increase frataxin levels.', 'thumbnail': 'https://serpapi.com/searches/6723b9906aa3644f4ad2ecab/images/3710c96b313c16681146737074ee0d82772038cd333f733f64735f38d6cb7e55.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8881443738937378}",,,,,,"['neutral', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01941537,"{'position': 1, 'link': 'https://www.dermatologyadvisor.com/news/severe-atopic-dermatitis-may-benefit-from-fezakinumab/', 'title': 'Severe Atopic Dermatitis May Benefit From Fezakinumab', 'source': 'Dermatology Advisor', 'date': 'Feb 16, 2018', 'snippet': 'Adults with moderate to severe atopic dermatitis (AD) have demonstrated \nsustained clinical improvement and drug tolerability when treated with the \nanti–...', 'thumbnail': 'https://serpapi.com/searches/6723b8aa98d8de716e457b45/images/4ce5466aac21503ee673c26ea1434a379379b6ca8be5d553fe0b311e417b02d4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7847092151641846}",,,,,,,,,,['neutral'],neutral,1 NCT04129528,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/clinical-diabetes-and-healthcare/articles/10.3389/fcdhc.2023.1244613/full', 'title': 'Investigating the value of glucodensity analysis of continuous glucose monitoring data in type 1 diabetes: an exploratory analysis', 'source': 'Frontiers', 'date': 'Sep 11, 2023', 'snippet': 'IntroductionContinuous glucose monitoring (CGM) devices capture \nlongitudinal data on interstitial glucose levels and are increasingly \nused...', 'thumbnail': 'https://serpapi.com/searches/6723b8b375f9740b5b7a09b5/images/b080c98e915c2fe2874d5678c1b62832eb15ef692b26dc1b3da97d69c141d18c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9110513925552368}",,,,,,,,,,['neutral'],neutral,1 NCT04392830,"{'position': 1, 'link': 'https://smanewstoday.com/news/avenue-acquires-license-rights-aj201-sbma-certain-countries/', 'title': 'Avenue acquires rights to AJ201 for SBMA in certain countries |...', 'source': 'SMA News Today', 'date': 'Mar 6, 2023', 'snippet': ""A new deal gives Avenue Therapeutics exclusive rights to AnnJi's AJ201 for \nspinal and bulbar muscular atrophy (SBMA) in certain countries."", 'thumbnail': 'https://serpapi.com/searches/6723b8fcbb64ac4559af247f/images/26aed8aaed95511d153b83878e76d9fcf27c2872e88ed469879cc6f099047982.png', 'sentiment': 'neutral', 'sentiment_prob': 0.940361738204956}",,,,,,,,,,['neutral'],neutral,1 NCT02985190,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-36193-w', 'title': 'Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation', 'source': 'Nature', 'date': 'Feb 3, 2023', 'snippet': 'Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders, \nrepresenting high risk of progression to acute myeloid leukaemia,...', 'thumbnail': 'https://serpapi.com/searches/6723b92e717bffe55912f9fb/images/6b8ce168718f9d51e61af9cdf64f108d87b2857438437fac8bb5d72e6f231091.png', 'sentiment': 'negative', 'sentiment_prob': 0.6979492902755737}",,,,,,,,,,['negative'],negative,0 NCT02819635,"{'position': 1, 'link': 'https://ibdnewstoday.com/2020/12/21/rinvoq-found-safe-effective-for-ulcerative-colitis-ongoing-phase-3-trial/', 'title': 'Rinvoq Found Safe, Effective for Ulcerative Colitis in Ongoing Phase 3 Trial', 'source': 'IBD News Today', 'date': 'Dec 21, 2020', 'snippet': 'Rinvoq (upadacitinib), an anti-inflammatory, was found to be safe and \neffective in treating moderate-to-severe ulcerative colitis in adults.', 'thumbnail': 'https://serpapi.com/searches/6723b9382fab626b124a568e/images/fdb244eca877b1f32bdaf1544223d8b1e3d82dd27048c42a8657d061afe4739a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5544900298118591}","{'position': 2, 'link': 'https://www.empr.com/home/news/rinvoq-approved-for-moderately-to-severely-active-ulcerative-colitis/', 'title': 'Rinvoq Approved for Moderately to Severely Active Ulcerative Colitis - MPR', 'source': 'Medical Professionals Reference', 'date': 'Mar 17, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Rinvoq (upadacitinib) \nfor the treatment of adults with moderately to severely active ulcerative \ncolitis.', 'thumbnail': 'https://serpapi.com/searches/6723b9382fab626b124a568e/images/fdb244eca877b1f3d428f46d7495614ee52bdb25d29659545b23a15ef3a3fdf5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8225958347320557}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01159288,"{'position': 1, 'link': 'https://www.nature.com/articles/s44222-022-00008-2', 'title': 'Technological challenges of biomembrane-coated top-down cancer nanotherapy', 'source': 'Nature', 'date': 'Jan 31, 2023', 'snippet': 'Top-down drug delivery strategies, including exosomes and cell \nmembrane-coated particles, can improve safety and efficacy owing to the \ninnate biointerfacial...', 'thumbnail': 'https://serpapi.com/searches/6723ba845416d8fd44a55d3e/images/3e7cc3b7a4a7512443d6286962d2ccb9281c19e8e038260452d727f0b6323097.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.48859986662864685}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/10.1002/ctm2.1448', 'title': 'Haematopoietic cell-derived exosomes in cancer development and therapeutics: From basic science to clinical practice', 'source': 'Wiley Online Library', 'date': 'Oct 13, 2023', 'snippet': 'The tumour microenvironment (TME) is a specialised niche involving \nintercellular communication among cancer cells and various host cells.', 'thumbnail': 'https://serpapi.com/searches/6723ba845416d8fd44a55d3e/images/3e7cc3b7a4a7512416d44792689d7df15c9adf8d0813f0b79004822eccc82490.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9238121509552002}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03186989,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02326-3', 'title': 'in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial', 'source': 'Nature', 'date': 'Apr 24, 2023', 'snippet': 'We sought to inhibit MAPT expression with a tau-targeting antisense \noligonucleotide (MAPT Rx ) and reduce tau levels in patients with mild AD.', 'thumbnail': 'https://serpapi.com/searches/6723ba8a059caf650f19bc72/images/369b284e08088b4229f951eff0513dea045141caacacc67c6eca08925395dfa4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8654584288597107}","{'position': 2, 'link': 'https://alzheimersnewstoday.com/news/biib080-shows-alzheimers-related-tau-protein-reduction-study/', 'title': ""BIIB080 shows Alzheimer's-related tau protein reduction in study |..."", 'source': ""Alzheimer's News Today"", 'date': 'Mar 31, 2023', 'snippet': ""New PET data from the Phase 1b extension study showed tau aggregation was \nreduced across all tested Alzheimer's patients brain regions."", 'thumbnail': 'https://serpapi.com/searches/6723ba8a059caf650f19bc72/images/369b284e08088b42512abe078dd3dabf72c89844b7e3cf59c3daceeb9a6e9adf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7541296482086182}","{'position': 3, 'link': 'https://www.researchgate.net/figure/Percent-free-from-Alzheimers-dementia-Kaplan-Meier-curves-were-generated-from_fig1_338994482', 'title': 'Percent free from Alzheimer’s dementia Kaplan–Meier curves were...', 'source': 'ResearchGate', 'date': 'Nov 18, 2020', 'snippet': ""Download scientific diagram | Percent free from Alzheimer's dementia \nKaplan–Meier curves were generated from Alzheimer's dementia cases and \ncognitively..."", 'thumbnail': 'https://serpapi.com/searches/6723ba8a059caf650f19bc72/images/369b284e08088b42f8a331a24339fe7e5d3ed84d5a87e7a1aa65b630e67366a2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8985739350318909}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT00331955,"{'position': 1, 'link': 'https://www.nature.com/articles/6605293', 'title': 'Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker', 'source': 'Nature', 'date': 'Sep 8, 2009', 'snippet': 'Histone deacetylase inhibitors (HDACi) can sensitise cancer cells to \ntopoisomerase inhibitors by increasing their access and binding to DNA.', 'thumbnail': 'https://serpapi.com/searches/6723ba949fd30930f1a86922/images/dc77ba92e9d1b613798e28edb5be5a787359e8ad900edc9e516ba687bcf767d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8336589932441711}",,,,,,,,,,['neutral'],neutral,1 NCT03478891,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/investigational-monoclonal-antibody-treat-ebola-safe-adults', 'title': 'Investigational monoclonal antibody to treat Ebola is safe in adults', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jan 25, 2019', 'snippet': 'The investigational Ebola treatment mAb114 is safe, well-tolerated, and \neasy to administer, according to findings from an early-stage clinical \ntrial published...', 'thumbnail': 'https://serpapi.com/searches/6723baf17ef9fa2958e90dd9/images/49db16959d81e73f87a1dcba932c4b157cdeffddee8939ad384d0fbae0a19948.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6047368049621582}",,,,,,,,,,['positive'],positive,1 NCT02136914,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-022-00291-1', 'title': 'Amantadine delayed release/extended release capsules significantly reduce OFF time in Parkinson’s disease', 'source': 'Nature', 'date': 'Mar 18, 2022', 'snippet': 'An amantadine delayed release/extended release (DR/ER) formulation (Gocovri \n® ) indicated for dyskinesia received additional FDA approval as an adjunct \nto...', 'thumbnail': 'https://serpapi.com/searches/6723baf9d16915e4d3acbd51/images/8e7accc706b56382bfd30b46a4d75e71d0dffcc6791ef4e42fcf013a9edf7d08.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6950205564498901}",,,,,,,,,,['neutral'],neutral,1 NCT02562755,"{'position': 1, 'link': 'https://www.genengnews.com/news/pexa-vec-nexavar-combination-fails-phase-iii-trial-in-liver-cancer/', 'title': 'Pexa-Vec/Nexavar Combination Fails Phase III Trial in Liver Cancer', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Aug 2, 2019', 'snippet': 'SillaJen and collaboration partner Transgene today separately acknowledged \nthe failure of their lead product Pexa-Vec (pexastimogene...', 'thumbnail': 'https://serpapi.com/searches/6723bb0251d84d25a324abe8/images/9f87ac300026344c5a6f96d4219991e23d15193b3fb5504f43ee7bf5296cbf5e.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7049565315246582}",,,,,,,,,,['negative'],negative,0 NCT02536404,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00061-2/fulltext', 'title': 'Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies', 'source': 'The Lancet', 'date': 'Mar 2, 2023', 'snippet': 'Etrasimod as induction and maintenance therapy for ulcerative colitis \n(ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies', 'thumbnail': 'https://serpapi.com/searches/6723bb06caddc353d22fa5a3/images/770190240893f28ec33812a4303ea0a60351ab1ea0768e810c29b198f877f233.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7826459407806396}",,,,,,,,,,['neutral'],neutral,1 NCT04551950,"{'position': 1, 'link': 'https://www.aacr.org/blog/2024/03/27/editors-picks-march-2024-synergys-impact-on-resistance-new-early-detection-tools-and-more/', 'title': 'Editors’ Picks, March 2024: Synergy’s Impact on Resistance, New Early Detection Tools, and More', 'source': 'American Association for Cancer Research', 'date': 'Mar 27, 2024', 'snippet': 'Studies of antibiotic combinations show that synergistic drug interactions \ncan accelerate the emergence of resistance.', 'thumbnail': 'https://serpapi.com/searches/6723bb4b18787d7fa1f0d295/images/23c05343ed949f3a5f79122c58dad3336893a7910e491d6385f1a78e4d74339f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8679391145706177}",,,,,,,,,,['neutral'],neutral,1 NCT02371369,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30764-0/fulltext', 'title': 'Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial', 'source': 'The Lancet', 'date': 'Jun 19, 2019', 'snippet': 'Tenosynovial giant cell tumour (TGCT), a rare, locally aggressive neoplasm, \noverexpresses colony-stimulating factor 1 (CSF1).', 'thumbnail': 'https://serpapi.com/searches/6723bb5517a2e2709600a414/images/7d3f193906622a767f5cf7794b86933b63f4e49cb6002891f0d184c82c209d25.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8731662631034851}",,,,,,,,,,['neutral'],neutral,1 NCT02997358,"{'position': 1, 'link': 'https://www.nejm.org/doi/abs/10.1056/NEJMoa2403394', 'title': 'Doxorubicin–Trabectedin with Trabectedin Maintenance in Leiomyosarcoma', 'source': 'The New England Journal of Medicine', 'date': 'Sep 4, 2024', 'snippet': 'We conducted a phase 3 trial involving patients with metastatic or \nunresectable leiomyosarcoma who had not received chemotherapy previously.', 'thumbnail': 'https://serpapi.com/searches/6723bb7d358539e84cebd4c9/images/46b1a26111fb3c1ae2637ce04f03849953ff15f3eb6420a17173c61ba611e1c1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9007108211517334}",,,,,,,,,,['neutral'],neutral,1 NCT02955823,"{'position': 1, 'link': 'https://lymphomahub.com/medical-information/chemo-free-combination-of-lenalidomide-rituximab-in-elderlyfrail-patients-with-mcl-and-dlbcl', 'title': 'Chemo-free combination of lenalidomide + rituximab in elderly/frail patients with MCL and DLBCL', 'source': 'Lymphoma Hub', 'date': 'Jan 24, 2022', 'snippet': 'The Lymphoma & CLL Hub is an independent medical education platform, \nsponsored by Beigene and Roche, and supported through educational...', 'thumbnail': 'https://serpapi.com/searches/6723bb80b7d31db0b3f97e88/images/0958f5f2f1667aa4e784c56a5508b1b8b06c9ed91f403279fc31a433a60769f5.png', 'sentiment': 'neutral', 'sentiment_prob': 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Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised, placebo-controlled phase 1/2 trial', 'source': 'The Lancet', 'date': 'Nov 19, 2019', 'snippet': 'Enterotoxigenic Escherichia coli causes diarrhoea, leading to substantial \nmortality and morbidity in children, but no specific vaccine...', 'thumbnail': 'https://serpapi.com/searches/6723bbdbb28e6b49d942248a/images/83fae9147f81b3d16dceb832bbd360dea7bd54dc685171efd511d955c5c98c36.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8389658331871033}",,,,,,,,,,['neutral'],neutral,1 NCT03910244,"{'position': 1, 'link': 'https://www.nejm.org/doi/abs/10.1056/NEJMoa2312749', 'title': 'Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia', 'source': 'The New England Journal of Medicine', 'date': '1 month ago', 'snippet': 'We conducted a randomized, placebo-controlled trial to evaluate the safety \nand efficacy of pomalidomide for the treatment of HHT.', 'thumbnail': 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Step Counts Had Greater QoL on SM-88', 'source': 'Cancer Network', 'date': 'Jan 18, 2021', 'snippet': 'A preliminary exploratory analysis from part 2 of the phase 2/3 \nTYME-88-Panc trial (NCT03512756) of SM-88 (racemetyrosine) in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/6723bdd29e38e54024ff1b39/images/098913c5c580a6c41330c48c998af4e853a9667418c7c71c56104fc5d089fa43.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9106556177139282}",,,,,,,,,,['neutral'],neutral,1 NCT02774187,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00264-x', 'title': 'Targeted therapy for hepatocellular carcinoma - Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Aug 11, 2020', 'snippet': 'The last 3 years have seen the emergence of promising targeted therapies \nfor the treatment of hepatocellular carcinoma (HCC).', 'thumbnail': 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'https://www.nature.com/articles/d41587-019-00013-8', 'title': 'Drug makers chase anti-flu pill', 'source': 'Nature', 'date': 'May 12, 2019', 'snippet': 'Drug makers are targeting flu virus vulnerabilities to develop antivirals \nthat not only stop infections in their tracks, but also temper emergence of \ndrug...', 'thumbnail': 'https://serpapi.com/searches/6723bd7bfcd69ee1d5dd4ef0/images/e87f6baf91a71ac1e4d10f3445f8c7805accc2e4ed60d7211c90ff2fd80a37c9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7620350122451782}",,,,,,,,,,['neutral'],neutral,1 NCT03238963,"{'position': 1, 'link': 'https://www.nature.com/articles/s41433-024-03017-0', 'title': 'ROBIN: a randomised, double-masked, placebo-controlled Phase IIa study of the AOC3 inhibitor BI 1467335 in diabetic retinopathy | Eye', 'source': 'Nature', 'date': 'May 28, 2024', 'snippet': 'To evaluate the safety and efficacy of BI 1467335 in patients with \nnon-proliferative diabetic retinopathy (NPDR). ROBIN is a Phase IIa,...', 'thumbnail': 'https://serpapi.com/searches/6723bdfe52a04e946bb2950c/images/e861d9bf174740a428a6769f7ac2580c657515f5f0edd25257df1a7f86acf928.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8770884275436401}",,,,,,,,,,['neutral'],neutral,1 NCT01629758,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0328-y', 'title': 'Cytokines in clinical cancer immunotherapy', 'source': 'Nature', 'date': 'Nov 9, 2018', 'snippet': 'In this review, we provide an overview of the novel trends in the cytokine \nimmunotherapy field that are yielding therapeutic agents for clinical \ntrials.', 'thumbnail': 'https://serpapi.com/searches/6723be1754163dba153e41b9/images/ab87ca260f64d4ddab1e2cf482867dfe10d300c3e12bbe44245680c2d5e32af3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7964982390403748}",,,,,,,,,,['neutral'],neutral,1 NCT01812616,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-021-01259-3', 'title': 'A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma | British Journal of Cancer', 'source': 'Nature', 'date': 'Feb 24, 2021', 'snippet': 'Preclinical data suggest some cannabinoids may exert antitumour effects \nagainst glioblastoma (GBM). Safety and preliminary efficacy of...', 'thumbnail': 'https://serpapi.com/searches/6723be2917b10e8d8c7765de/images/0925fd098e31048b175508d5a4600d0047d04285c7971693a504b23d67c14757.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9131330251693726}",,,,,,,,,,['neutral'],neutral,1 NCT06097273,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/stockwatch-analysts-mixed-on-moderna-despite-750m-financing-vaccine-updates/', 'title': 'StockWatch: Analysts Mixed on Moderna Despite $750M Financing, Vaccine Updates', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Apr 1, 2024', 'snippet': 'Analysts remain decidedly mixed in their assessment of Moderna despite a \nflurry of financing and clinical updates at its recent Vaccine Day.', 'thumbnail': 'https://serpapi.com/searches/6723be5e15c740d14127ec0b/images/b04a0176f946f1b3884efdecc2c9941cd3a0d8934205c4d159a4b8f70dbe0198.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.608450710773468}",,,,,,,,,,['neutral'],neutral,1 NCT03985293,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20230625157557/en/Pfizer-Provides-Update-on-GLP-1-RA-Clinical-Development-Program-for-Adults-with-Obesity-and-Type-2-Diabetes-Mellitus', 'title': 'Pfizer Provides Update on GLP-1-RA Clinical Development Program for Adults with Obesity and Type 2 Diabetes Mellitus', 'source': 'Business Wire', 'date': 'Jun 26, 2023', 'snippet': 'Pfizer Inc. (NYSE: PFE) today announced its decision to continue to \nprogress one oral late-stage glucagon-like peptide-1 receptor agonist...', 'thumbnail': 'https://serpapi.com/searches/6723be82f922f69a88ec5daa/images/62ffb0cbf831a756732f0c5eb72dd8b79716d15a022cf09dac041ff5e507db25.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9171797037124634}",,,,,,,,,,['neutral'],neutral,1 NCT02453256,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30318-0/abstract', 'title': 'Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'Aug 28, 2020', 'snippet': 'A phase 2 trial of tocilizumab showed preliminary evidence of efficacy in \nsystemic sclerosis. We assessed skin fibrosis and systemic...', 'thumbnail': 'https://serpapi.com/searches/6723be8be8735a1b3a72487d/images/25a82e5e23b98bf182f22c997ef6c037d9863fbf449c747a2185ec56a0d1ba1d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7601886987686157}","{'position': 2, 'link': 'https://www.empr.com/home/news/actemra-tocilizumab-injection-pulmonary-function-systemic-sclerosis-interstitial-lung-disease/', 'title': 'Actemra Gains New Indication for Systemic Sclerosis-Associated Interstitial Lung Disease', 'source': 'Medical Professionals Reference', 'date': 'Mar 5, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Actemra (tocilizumab; \nGenentech) subcutaneous injection for slowing the rate of decline in \npulmonary...', 'thumbnail': 'https://serpapi.com/searches/6723be8be8735a1b3a72487d/images/25a82e5e23b98bf18d320586e3a6717a143e91fa8b839546f270d8a2a8bec775.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7725078463554382}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00292045,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-01876-6', 'title': 'Toll-like receptor 9 agonists and combination therapies: strategies to modulate the tumour immune microenvironment for systemic anti-tumour immunity | British Journal of Cancer', 'source': 'Nature', 'date': 'Jul 28, 2022', 'snippet': 'Over the past decade, tremendous progress has taken place in tumour \nimmunotherapy, relying on the fast development of combination therapy...', 'thumbnail': 'https://serpapi.com/searches/6723bec77ebde5eeab29f23c/images/2de0e2dcfd40d577928f9d240e34ae277b1f47fed6194554549046320cd7107f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7099482417106628}",,,,,,,,,,['neutral'],neutral,1 NCT01721148,"{'position': 1, 'link': 'https://breastcancer-news.com/2017/02/08/new-drug-shown-to-effectively-block-breast-cancer-bone-degradation/', 'title': 'Breast Cancer Patients with Bone Degradation May Benefit from Drug in Clinical Testing', 'source': 'breastcancer-news.com', 'date': 'Feb 8, 2017', 'snippet': 'A new oral drug in a first-in-human clinical trial has shown promise in \ninhibiting the bone degradation caused by breast cancer cells.', 'thumbnail': 'https://serpapi.com/searches/6723bf06dda9d9c73b31bfd1/images/da9870d9ea6ad915a848a285e9ccb1af06208193a32dc6fb2a9e7c8b5c442605.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6646877527236938}",,,,,,,,,,['neutral'],neutral,1 NCT05876767,"{'position': 1, 'link': 'https://www.nature.com/articles/s41435-023-00221-y', 'title': 'IL-2 immunotherapy for targeting regulatory T cells in autoimmunity', 'source': 'Nature', 'date': 'Sep 23, 2023', 'snippet': 'A new and promising focus in drug development are IL-2-based approaches for \nin vivo targeted expansion of T reg or for enhancement of their \nsuppressive...', 'thumbnail': 'https://serpapi.com/searches/6723bf12e335ec621cd245ff/images/16dcf4b1db34ff3deb9b6bb074109925a5c723f5f19cd2702855903454663198.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6119940280914307}",,,,,,,,,,['neutral'],neutral,1 NCT04101721,"{'position': 1, 'link': 'https://www.empr.com/home/news/eylea-approved-for-preterm-infants-with-retinopathy-of-prematurity/', 'title': 'Eylea Approved for Preterm Infants With Retinopathy of Prematurity', 'source': 'Medical Professionals Reference', 'date': 'Feb 9, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Eylea (aflibercept) for \nthe treatment of preterm infants with retinopathy of prematurity (ROP).', 'thumbnail': 'https://serpapi.com/searches/6723bf296531cb46dc2de16b/images/d7a5f5d0420ccf410d69e501cc0c7813b8c7825726af08bee1476a9099158a2f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8532078266143799}",,,,,,,,,,['neutral'],neutral,1 NCT01395641,"{'position': 1, 'link': 'https://www.cgtlive.com/view/upstaza-approved-aadc-deficiency-uk', 'title': 'Upstaza Approved for AADC Deficiency in UK', 'source': 'CGTLive®', 'date': 'Nov 21, 2022', 'snippet': 'Upstaza (eladocagene exuparvovec), a recombinant adeno-associated virus \nserotype 2 (AAV2)-based gene therapy intended to treat aromatic L–amino \nacid...', 'thumbnail': 'https://serpapi.com/searches/6723bf5571b0e8d34ac50de2/images/5c8bbeee6cf16c505aba741514eb1e8d35bc5a9a3eef4b0fd5b90ec14d951e5b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8430208563804626}","{'position': 2, 'link': 'https://aadcnews.com/news/upstaza-boosts-patient-survival-quality-life-prediction-model/', 'title': 'Upstaza boosts patient survival, quality of life in prediction...', 'source': 'AADC News', 'date': 'Oct 11, 2023', 'snippet': 'Treatment with Upstaza (eladocagene exuparvovec) is estimated to prolong \nsurvival and lead to life quality gains for aromatic l-amino acid \ndecarboxylase (AADC)...', 'thumbnail': 'https://serpapi.com/searches/6723bf5571b0e8d34ac50de2/images/5c8bbeee6cf16c504ab71881962cde804522c3736ddec58b15eee917814536a0.png', 'sentiment': 'positive', 'sentiment_prob': 0.8483631610870361}","{'position': 3, 'link': 'https://www.cgtlive.com/view/hwu-questions-remaining-aadc-deficiency', 'title': 'Paul Wuh-Liang Hwu, MD, PhD, on Questions Remaining With AADC Deficiency', 'source': 'CGTLive®', 'date': 'Jul 22, 2022', 'snippet': 'CGTLive spoke with study investigator Paul Wuh-Liang Hwu, MD, PhD, \nprofessor, National Taiwan University Hospital, about Upstaza as well as \nhis work in Pompe...', 'thumbnail': 'https://serpapi.com/searches/6723bf5571b0e8d34ac50de2/images/5c8bbeee6cf16c50a5a21572373a1e430125019ca06db907bad6450c358703a3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9344761371612549}","{'position': 4, 'link': 'https://aadcnews.com/news/review-highlights-gene-therapies-that-greatly-improve-potential-for-cure-ptc-aadc/', 'title': 'Review Highlights Advances in Gene Therapies With Potential for Cure', 'source': 'AADC News', 'date': 'Mar 4, 2021', 'snippet': 'The science behind viral gene therapy — which may hold a potential cure in \na single treatment for genetic diseases such as aromatic l-amino...', 'thumbnail': 'https://serpapi.com/searches/6723bf5571b0e8d34ac50de2/images/5c8bbeee6cf16c50cd331b6c2bc82f504fe3563a378806a4245491a567fdb5b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6926557421684265}","{'position': 5, 'link': 'https://aadcnews.com/news/upstaza-gene-therapy-aadc-deficiency-approved-uk/', 'title': 'Upstaza, Gene Therapy for AADC Deficiency, Approved in UK', 'source': 'AADC News', 'date': 'Nov 23, 2022', 'snippet': 'The gene therapy Upstaza (eladocagene exuparvovec) has been approved in the \nUK to treat adults and children, 18 months and older, with aromatic l-amino \nacid...', 'thumbnail': 'https://serpapi.com/searches/6723bf5571b0e8d34ac50de2/images/5c8bbeee6cf16c50daffa4731ea4901bd8fb26f6068101e16d70229502cf47b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.784906268119812}",,,,,,"['neutral', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01483599,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1501646', 'title': 'A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 9, 2015', 'snippet': 'Little is known about the effect of specific anti–interleukin-23 therapy, \nas compared with established anti–tumor necrosis factor therapies,...', 'thumbnail': 'https://serpapi.com/searches/6723bfba6a5dd3df11063160/images/88859825ee0d647cd9940f87fcf46b68832548419e053641eba746e19c4d22d0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7835938930511475}",,,,,,,,,,['neutral'],neutral,1 NCT04525131,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-021-03836-z', 'title': 'Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex', 'source': 'Nature', 'date': 'May 31, 2021', 'snippet': 'Ciclopirox (CPX) is an FDA-approved topical antifungal agent that has \ndemonstrated preclinical anticancer activity in a number of solid and \nhematologic...', 'thumbnail': 'https://serpapi.com/searches/6723bfbbecf15028b3d55008/images/f0a7942f2d11284c1bb21e56e33ed4d13337748392f6f38773070a1e718ad85e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7911655902862549}",,,,,,,,,,['neutral'],neutral,1 NCT04076462,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/news/manufacturing-issue-delays-decision-on-acromegaly-therapy/', 'title': 'Manufacturing Issue Delays Decision on Acromegaly Therapy', 'source': 'Endocrinology Advisor', 'date': '6 days ago', 'snippet': 'The Food and Drug Administration (FDA) has issued a Complete Response \nLetter (CRL) to Camurus regarding the New Drug Application (NDA) for...', 'thumbnail': 'https://serpapi.com/searches/6723c006f3cbfa08dbfc74fd/images/7ce4df4a318c6fab8ca62848f9992aa24823d7da584b287d4a6ba2d520477fab.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8548938035964966}",,,,,,,,,,['neutral'],neutral,1 NCT02496741,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2018.00335/full', 'title': 'Re-purposing Chloroquine for Glioblastoma: Potential Merits and Confounding Variables', 'source': 'Frontiers', 'date': 'Aug 27, 2018', 'snippet': 'There is a growing evidence that antimalarial chloroquine could be \nre-purposed for cancer treatment. A dozen of clinical trials have been...', 'thumbnail': 'https://serpapi.com/searches/6723c0de81bab791da7f1998/images/a077b767b49bcb9a73bdafdebcf7bbf2a000298d17480ecf498833a52c2de082.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9061118960380554}",,,,,,,,,,['neutral'],neutral,1 NCT02160145,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1710030', 'title': 'Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease', 'source': 'The New England Journal of Medicine', 'date': 'Nov 4, 2017', 'snippet': 'In a previous trial involving patients with early autosomal dominant \npolycystic kidney disease (ADPKD; estimated creatinine clearance,...', 'thumbnail': 'https://serpapi.com/searches/6723c0e98b7ba7b65972bf52/images/384d068f9f93c4a31dfd099de1e321f0dfe1f5e651076e44a45ed5a4a85f51fd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8663855195045471}",,,,,,,,,,['neutral'],neutral,1 NCT05249621,"{'position': 1, 'link': 'https://pompediseasenews.com/news/pompe-disease-treatment-mze001-shows-promise-phase-1-trial/', 'title': 'Pompe disease treatment MZE001 shows promise in Phase 1 trial |...', 'source': 'Pompe Disease News', 'date': 'Mar 9, 2023', 'snippet': 'The experimental Pompe disease treatment MZE001 was well tolerated and \nreduced glycogen levels in healthy volunteers in a Phase 1 trial.', 'thumbnail': 'https://serpapi.com/searches/6723c0f30d379f3731cbd6b5/images/94b1b0eada3952fee4a22d657eccd7c88de191c1ddc44ac311462e5f5dabb3c6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8214936852455139}",,,,,,,,,,['positive'],positive,1 NCT03678259,"{'position': 1, 'link': 'https://fapnewstoday.com/news/imaging-agent-at-01-can-detect-amyloid-deposits-in-heart-of-asymptomatic-amyloidosis-patients-study/', 'title': 'AT-01 Can Detect Amyloid Deposits in Heart in Asymptomatic Patients', 'source': 'FAP News Today', 'date': 'May 24, 2021', 'snippet': ""A Phase 1/2 trial showed that Attralus' imaging agent AT-01 is able to \ndetect amyloid deposits even in patients without heart symptoms."", 'thumbnail': 'https://serpapi.com/searches/6723c1087f371927460f9504/images/68b3279f3507a17f7b3238facf4f957f7d0dc8dc87d38e18fbec95bdc5438c9d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.812371551990509}",,,,,,,,,,['neutral'],neutral,1 NCT04328961,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-43185-9', 'title': 'Simultaneous LC–MS/MS method for the quantitation of Azithromycin, Hydroxychloroquine and its metabolites in SARS-CoV-2(−/ +) populations using dried blood spots', 'source': 'Nature', 'date': 'Sep 30, 2023', 'snippet': 'In this study, we developed and validated the first sensitive and selective \nsimultaneous LC–MS/MS method to accurately quantitate the concentration of \nHCQ, HCQ...', 'thumbnail': 'https://serpapi.com/searches/6723c10a17b10e8d8c7767e4/images/7714df5f2e717adcdc6d4390e3e0c035cac339b113c3adb623798f180e5d0a0d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8897202610969543}",,,,,,,,,,['neutral'],neutral,1 NCT02678689,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.785841/full', 'title': 'Natural History Studies in NCL and Their Expanding Role in Drug Development: Experiences From CLN2 Disease and Relevance for Clinical Trials', 'source': 'Frontiers', 'date': 'Feb 7, 2022', 'snippet': 'Conducting clinical trials in rare diseases is challenging. In trials that \naim to use natural history control cohorts for evaluation of...', 'thumbnail': 'https://serpapi.com/searches/6723c030be8013a020dc9325/images/c02049ff8d03b099db1d4fabad1760dfc0390303c211437e68dbab5b1a807230.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8298519253730774}","{'position': 2, 'link': 'https://battendiseasenews.com/news/brineura-approved-as-batten-treatment-in-europe-us-as-clinical-trials-continue/', 'title': 'Brineura Approved as Batten Treatment in Both Europe and US as Clinical Studies Continue', 'source': 'Batten Disease News', 'date': 'Jun 2, 2017', 'snippet': 'Brineura, by BioMarin, is now approved to treat CLN2 type Batten disease in \nEurope and the U.S., as clinical trials continue to gather data.', 'thumbnail': 'https://serpapi.com/searches/6723c030be8013a020dc9325/images/c02049ff8d03b099602a34e3fad976ea10de6c5aaf98da0e87ed98a195bba057.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.595138430595398}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02302066,"{'position': 1, 'link': 'https://www.infectiousdiseaseadvisor.com/features/second-dose-of-tetravalent-dengue-vaccine-candidate-shows-enhanced-immunogenicity/', 'title': 'Second Dose of Tetravalent Dengue Vaccine Candidate Shows Enhanced Immunogenicity', 'source': 'Infectious Disease Advisor', 'date': 'Aug 18, 2017', 'snippet': 'A tetravalent dengue vaccine candidate (TDV) was found to be safe and \nimmunogenic in an ongoing phase 2 trial.', 'thumbnail': 'https://serpapi.com/searches/6723c08bd19f1513f5c5216f/images/b008219db6169ec9ba3e21add8a3b9da06ad2bfa1b6b394f2b0bac6a835232c1.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5370800495147705}",,,,,,,,,,['positive'],positive,1 NCT04727138,"{'position': 1, 'link': 'https://www.genengnews.com/topics/artificial-intelligence/bms-collaboration-paying-off-for-exscientia/', 'title': 'BMS Collaboration Paying Off for Exscientia', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Feb 7, 2023', 'snippet': 'Exscientia, the Oxford-based pioneer in artificial intelligence (AI)-based \ndrug development, has advanced the first of three candidates...', 'thumbnail': 'https://serpapi.com/searches/6723c08df6aa5324950753f5/images/aedd92eee461725dbbb84bea82351b0fda7cd5143935ffbc0cb062fbcd00ec70.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7788528800010681}",,,,,,,,,,['positive'],positive,1 NCT02213003,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Illustration-of-the-Sernova-Cell-Pouch-A-Plugs-in-situ-within-the-Cell-Pouch-B_fig1_309010262', 'title': 'Figure 1. Illustration of the Sernova Cell Pouch™. A, Plugs in situ...', 'source': 'ResearchGate', 'date': 'Feb 17, 2018', 'snippet': 'Despite advances in clinical islet transplanta-tion, intraportal islet \ndelivery is limited by en-graftment, neovascularization, immune protection \nand...', 'thumbnail': 'https://serpapi.com/searches/6723c0a06de1e45934c48bd3/images/d1516387d8aa42369e467f274e006c4dd0d03622c8e50884d7756ab75580b1c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8343610763549805}",,,,,,,,,,['neutral'],neutral,1 NCT02029573,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Diagnostic-prognostic-and-predictive-biomarkers-in-glioblastoma_tbl1_379918538', 'title': 'Diagnostic, prognostic and predictive biomarkers in glioblastoma.', 'source': 'ResearchGate', 'date': 'May 2, 2024', 'snippet': 'Glioblastoma, the most aggressive and common malignant primary brain \ntumour, is characterized by infiltrative growth, abundant \nvascularization,...', 'thumbnail': 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significantly reduced relapse rates, the \nrisk of disability progression, and MRI measures of disease activity at 96 \nweeks.', 'thumbnail': 'https://serpapi.com/searches/6723c220b4fe873094b79b93/images/6c49c3f6586e3eddacf460f6a5c868998677bb468e6411504a0aedf6fe61d574.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7651755213737488}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/04/11/mavenclad-benefits-ms-sustained-up-15-years-after-last-treatment/', 'title': 'Mavenclad benefits for MS sustained up to 15 years after last treatment', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 11, 2023', 'snippet': 'The benefits of Mavenclad (cladribine) were sustained for up to 15 years \nafter its last treatment course in people with relapsing MS.', 'thumbnail': 'https://serpapi.com/searches/6723c220b4fe873094b79b93/images/6c49c3f6586e3edd8036cdb26538a39def1547ce10a438dc9cfc459a1d876333.png', 'sentiment': 'positive', 'sentiment_prob': 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Learn more about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/6723c220b4fe873094b79b93/images/6c49c3f6586e3edd715624930d26ed744bddaef948ce21b40615da1f441bb785.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9230253100395203}",,,,,,,"['neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT03728634,"{'position': 1, 'link': 'https://fapnewstoday.com/news/results-fully-enrolled-fap-neuro-ttransform-trial-eplontersen-expected-mid-2022/', 'title': 'Results From Fully Enrolled NEURO-TTRansform Trial Due Mid-2022', 'source': 'FAP News Today', 'date': 'Aug 2, 2021', 'snippet': ""Patient enrollment is complete for the NEURO-TTRansform trial testing \nIonis' eplontersen in adults with FAP, with results due in mid-2022."", 'thumbnail': 'https://serpapi.com/searches/6723c221fc40bf3211c18dee/images/01ec5679f5c9cd9ef7b5f6449db15389176d309c888b3679c30c4c70fb1c5e94.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8340455889701843}",,,,,,,,,,['neutral'],neutral,1 NCT04964557,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/ionis-provides-update-on-development-program-evaluating-pcsk9-antisense-medicine-for-the-treatment-of-hypercholesterolemia-301631819.html', 'title': 'Ionis provides update on development program evaluating PCSK9 antisense medicine for the treatment of hypercholesterolemia', 'source': 'PR Newswire', 'date': 'Sep 23, 2022', 'snippet': 'PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced \nthat topline results from the Phase 2b SOLANO study in patients...', 'thumbnail': 'https://serpapi.com/searches/6723c22aa54d7ebee9d523b0/images/a9a2011b89ae420f15a620510e26cd07c0ca7dc368068e16f6295b6ed10f6fa5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9042848348617554}",,,,,,,,,,['neutral'],neutral,1 NCT04992260,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-50802-2', 'title': 'Efficacy, immunogenicity and safety of CoronaVac® in children and adolescents aged 6 months to 17 years: a multicenter, randomized, double-blind, placebo-controlled phase III clinical trial', 'source': 'Nature', 'date': 'Aug 6, 2024', 'snippet': 'Safe and effective vaccines against COVID-19 for children and adolescents \nare needed. This international multicenter, randomized,...', 'thumbnail': 'https://serpapi.com/searches/6723c24508abe4f8a8c7fb1c/images/20acc24a5c174b51a1d5653bfae55acd63efadb8bd09fac8e5c6b4ce849aa70f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6900764107704163}",,,,,,,,,,['neutral'],neutral,1 NCT01979536,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1203471/full', 'title': 'Brentuximab vedotin use in pediatric anaplastic large cell lymphoma', 'source': 'Frontiers', 'date': 'May 18, 2023', 'snippet': '1University of Michigan, Division of Pediatric Hematology-Oncology, Ann \nArbor, MI, United States; 2Eastern Virginia Medical School,...', 'thumbnail': 'https://serpapi.com/searches/6723c24ad364b4d1b56f896d/images/2dd6c17fce5cb5568cdba5b9405b3b984c2f726eee71ebf220f27c663d5ead48.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9270607233047485}",,,,,,,,,,['neutral'],neutral,1 NCT04192214,"{'position': 1, 'link': 'https://www.esanum.de/today/posts/bc-007-und-long-covid-lizenz-zur-heilung-noch-ausstehend', 'title': 'BC 007 und Long Covid: Lizenz zur Heilung noch ausstehend', 'source': 'esanum', 'date': 'Oct 11, 2021', 'snippet': 'Ein Berliner Start-up mit dem Namen ""Berlin Cures"" hat bereits vor einigen \nJahren ein Medikament entwickelt, das sich zur Behandlung von...', 'thumbnail': 'https://serpapi.com/searches/6723c24f460b157f97ff9d4f/images/06255a7aee2a1fd5ab0fff9c05d601594383c8eb88886498f244257c983a5f3a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8751393556594849}",,,,,,,,,,['neutral'],neutral,1 NCT01794507,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/relapsed-refractory-multiple-myeloma-clinical-trial-venetoclax-bortezomib-dexamethasone-combo-promising-effectiveness-safety/', 'title': 'Myeloma Trial of Venclexta, Velcade, Dexamethasone Combo Shows Promising Results', 'source': 'Myeloma Research News', 'date': 'Oct 13, 2017', 'snippet': 'Adding Venclexta (venetoclax) to Velcade (bortezomib) and dexamethasone has \nshown promising effectiveness and an acceptable safety profile in multiple \nmyeloma...', 'thumbnail': 'https://serpapi.com/searches/6723c34d3ad34d921e89426c/images/358ea7f939474aa730d170e1a77124ba987acc70dda748a6d53d14b72af2b42a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5157041549682617}",,,,,,,,,,['neutral'],neutral,1 NCT05119686,"{'position': 1, 'link': 'https://www.rheumatologyadvisor.com/features/fda-roundup-emerging-drug-treatments-for-gout/', 'title': 'FDA Roundup: Pipeline Drugs for Gout', 'source': 'Rheumatology Advisor', 'date': 'Feb 9, 2024', 'snippet': 'There have been promising recent advancements in gout treatment, \nparticularly with innovative developments entering phase 3 clinical trials.', 'thumbnail': 'https://serpapi.com/searches/6723c36d0e6db34d71d352d3/images/943181bb5874bb9bff1f94d6c77b698623418ca604bd6cdf7e9ff994c45b8ae7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.9072781205177307}",,,,,,,,,,['positive'],positive,1 NCT03363893,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-40061-y', 'title': 'Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib', 'source': 'Nature', 'date': 'Jul 24, 2023', 'snippet': 'Samuraciclib is a selective oral CDK7-inhibitor. 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'source': 'Hematology Advisor', 'date': 'Sep 11, 2023', 'snippet': 'Brixadi® (buprenorphine) extended-release subcutaneous injection is now \navailable for the treatment of moderate to severe opioid use...', 'thumbnail': 'https://serpapi.com/searches/6723c2cc39e23253ca9ded0c/images/545456683568279abce809b84b30c70aab867b7670092a7900488c18134d4cc5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9039714336395264}",,,,,,,,,,['neutral'],neutral,1 NCT03948763,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01579-1', 'title': 'mRNA vaccines in disease prevention and treatment | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Sep 20, 2023', 'snippet': 'mRNA vaccines have emerged as highly effective strategies in the \nprophylaxis and treatment of diseases, thanks largely although not totally \nto their...', 'thumbnail': 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'date': 'Oct 24, 2022', 'snippet': 'Bevacizumab along with reirradiation extended progression-free survival \ncompared with bevacizumab alone for patients with recurrent glioblastoma \nmultiforme.', 'thumbnail': 'https://serpapi.com/searches/6723c4038de63cf49777a864/images/ef9f7df27832b42372fa22554d6c06286c1cc022fe247bdb5b4f2892a36ca70a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6825342774391174}",,,,,,,,,,['positive'],positive,1 NCT01154140,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1408440', 'title': 'First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Dec 4, 2014', 'snippet': 'We conducted an open-label, phase 3 trial comparing crizotinib with \nchemotherapy in 343 patients with advanced ALK-positive nonsquamous...', 'thumbnail': 'https://serpapi.com/searches/6723c40fa25104bf530ff4aa/images/2f8f8dc177cc4b94c600b05d791e67dcf38b6c29257144091bf6e3cef2b162fd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9059361219406128}",,,,,,,,,,['neutral'],neutral,1 NCT05111249,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/news/branaplam-dosing-huntingtons-trial-paused-side-effects/', 'title': 'Dosing Paused in Phase 2 Branaplam Trial Due to Possible Side Effects', 'source': ""Huntington's Disease News"", 'date': 'Aug 30, 2022', 'snippet': ""Due to possible side effects, dosing is being paused in the Phase 2 \nVIBRANT-HD clinical trial of oral branaplam (LMI070) in adults with \nHuntington's disease."", 'thumbnail': 'https://serpapi.com/searches/6723c41cc97e35cb6520d918/images/d7dc2d378e0ab3aa1a2d3b45901439d9fc6b7211154d764b55d72a07d7d98e2b.png', 'sentiment': 'negative', 'sentiment_prob': 0.508709728717804}",,,,,,,,,,['negative'],negative,0 NCT02040506,"{'position': 1, 'link': 'https://www.oncozine.com/magenta-therapeutics-voluntarily-stops-phase-1-2-study-of-adc-mgta-117-due-to-serious-adverse-event/', 'title': 'Magenta Therapeutics Voluntarily Stops Phase 1/2 Study of ADC MGTA-117 Due to Serious Adverse Event', 'source': ""Onco'Zine"", 'date': 'Feb 11, 2023', 'snippet': 'Clinical-stage biotech Magenta Therapeutics confirmed that latest \nparticipant dosed at the Cohort 3 level (0.08 mg/kg) in the ongoing \nMGTA-117 Phase 1/2...', 'thumbnail': 'https://serpapi.com/searches/6723c4694e9efc5a64221da6/images/b638d94d7322015dff5cfa5900819671abfadde189a6a8df32261f5662d3c22b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7435821294784546}",,,,,,,,,,['neutral'],neutral,1 NCT02395601,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-02181-7', 'title': 'EZH2 presents a therapeutic target for neuroendocrine tumors of the small intestine', 'source': 'Nature', 'date': 'Nov 23, 2021', 'snippet': 'Small intestinal neuroendocrine tumors (SI-NETs) are slow-growing tumors \nthat seem genetically quite stable without highly recurrent...', 'thumbnail': 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The RTS,S/AS01 malaria candidate vaccine was...', 'thumbnail': 'https://serpapi.com/searches/6723c4c6c024d1935d72cfb8/images/007010cb5136254227563c489cf40a8910c30897ba01b8ce3493db8539941d1e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5545780658721924}",,,,,,,,,,['neutral'],neutral,1 NCT01865487,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-018-0075-3', 'title': 'Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making', 'source': 'Nature', 'date': 'Sep 17, 2018', 'snippet': 'Unlike drug dose optimisation, mathematical modelling has not been applied \nto vaccine dose finding.', 'thumbnail': 'https://serpapi.com/searches/6723c4e2d111956b5d3ac7b2/images/3820e2259cfee66219505e18f85b832507fabcf597048dd677dff20e618f4bc1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8495684862136841}",,,,,,,,,,['neutral'],neutral,1 NCT04050085,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-023-00364-1', 'title': 'Applications and clinical trial landscape using Toll-like receptor agonists to reduce the toll of cancer', 'source': 'Nature', 'date': 'Mar 8, 2023', 'snippet': 'In this review, we describe the TLR agonists that are being evaluated \nclinically as new therapies for solid tumors.', 'thumbnail': 'https://serpapi.com/searches/6723c4e6ca6f0c674d72a919/images/3b60f77a72cd38592ee8143e3f552cfb839e35a92899a18e70c70dc8de65cf72.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9042466282844543}",,,,,,,,,,['neutral'],neutral,1 NCT00921947,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/abs/pii/S014181302400062X', 'title': 'Self-adjuvant multiepitope nanovaccine based on ferritin induced long-lasting and effective mucosal immunity against H3N2 and H1N1 viruses in mice', 'source': 'ScienceDirect.com', 'date': 'Jan 7, 2024', 'snippet': 'The prokaryotically expressed multiepitope nanovaccine elicits long-lasting \nmucosal immunity, broad humoral immunity, and robust cellular immunity \nwithout any...', 'thumbnail': 'https://serpapi.com/searches/6723c4f8213c87b600cd7ce8/images/33f10b0df2ba6a2be03eee8bed10097ac04bb3bc936268d8502fb73438d47e12.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6536120176315308}",,,,,,,,,,['neutral'],neutral,1 NCT01483144,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1916063', 'title': 'Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 9, 2020', 'snippet': 'The efficacy and safety of combination therapy with eflornithine and \nsulindac, as compared with either drug alone, in delaying disease...', 'thumbnail': 'https://serpapi.com/searches/6723c54d2da98353886f0da6/images/921079b0bc211c37d621021fa8b1f7527c3a73ec9905b77dc6b8ae27b3acaf05.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8110136985778809}",,,,,,,,,,['neutral'],neutral,1 NCT04241315,"{'position': 1, 'link': 'https://www.pennmedicine.org/news/news-releases/2022/december/fda-approves-glowing-tumor-imaging-drug-for-lung-cancer-surgery', 'title': 'FDA Approves “Glowing Tumor” Imaging Drug for Lung Cancer Surgery', 'source': 'Penn Medicine', 'date': 'Dec 16, 2022', 'snippet': 'Glowing tumor” targeted imaging agent approved for use in lung cancer \nsurgery after clinical testing led by Penn Medicine.', 'thumbnail': 'https://serpapi.com/searches/6723c58352a04e946bb29984/images/b39b425afac25a057532b9d0b13607a7746332cffaeb25073529ebe87621e874.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7413339018821716}",,,,,,,,,,['neutral'],neutral,1 NCT00864032,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.3103', 'title': 'BRAF mutation and its inhibitors in sarcoma treatment - Liu - 2020 - Cancer Medicine', 'source': 'Wiley Online Library', 'date': 'May 31, 2020', 'snippet': 'Cancer Medicine is an open access, broad-scope oncology journal covering \nclinical cancer research, cancer biology, cancer prevention,...', 'thumbnail': 'https://serpapi.com/searches/6723c586a54d7ebea390b707/images/c7813b8507d029096837c779090a367e7172145bfdb7c1806200b8a84dc918e3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9235926866531372}",,,,,,,,,,['neutral'],neutral,1 NCT01396499,"{'position': 1, 'link': 'https://www.jci.org/articles/view/78090/figure/2', 'title': 'MicroRNA regulation of lymphocyte tolerance and autoimmunity', 'source': 'JCI - Welcome', 'date': 'Jun 1, 2015', 'snippet': 'PI3K inhibitors are currently in clinical trials for acute and advanced \nleukemia (ClinicalTrials.gov identifiers NCT01756118 and...', 'thumbnail': 'https://serpapi.com/searches/6723c59ef7adbffdff08182c/images/be8540f67c684813fcd924f86361cfe51b2f2480ed953cfaa442ed8e9ed2e6a5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9191775918006897}",,,,,,,,,,['neutral'],neutral,1 NCT02178358,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1188277/full', 'title': 'Current insights into the hepatic microenvironment and advances in immunotherapy for hepatocellular carcinoma', 'source': 'Frontiers', 'date': '٠٨\u200f/٠٢\u200f/٢٠٢٤', 'snippet': 'This review aims to provide insights into the hepatic immune \nmicroenvironment in HCC and summarize the mechanisms of action and clinical \nusage of...', 'thumbnail': 'https://serpapi.com/searches/6723c5a6b4b72de072b1efd0/images/05873397379eb97ece0544fca093b923022ed8d421436214d3da6a7140b732d9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8974184393882751}",,,,,,,,,,['neutral'],neutral,1 NCT00511238,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/myeloma-study-finds-pomalyst-more-cost-effective-than-kyprolis-or-darzalex/', 'title': 'Myeloma Study Finds Pomalyst More Cost-Effective Than Two Rivals', 'source': 'Myeloma Research News', 'date': 'Oct 30, 2017', 'snippet': 'Read about a study reporting that a combination of Pomalyst and \ndexamethasone is a more cost-effective therapy for myeloma than Kyprolis \nor...', 'thumbnail': 'https://serpapi.com/searches/6723c5b0d364b4d16b1c5df7/images/d5261506c7d82f535408254ebc88aed70c705384a1ceea563be848edba7bd474.png', 'sentiment': 'positive', 'sentiment_prob': 0.5470622777938843}",,,,,,,,,,['positive'],positive,1 NCT05352815,"{'position': 1, 'link': 'https://www.researchgate.net/publication/380177828_Once-weekly_insulins_a_promising_approach_to_reduce_the_treatment_burden_in_people_with_diabetes', 'title': '(PDF) Once-weekly insulins: a promising approach to reduce the treatment burden in people with diabetes', 'source': 'ResearchGate', 'date': 'Aug 30, 2024', 'snippet': 'PDF | Despite the availability of new classes of glucose-lowering drugs \nthat improve glycaemic levels and minimise long-term complications,...', 'thumbnail': 'https://serpapi.com/searches/6723c65bc76a3acd090f8664/images/33ce6b930e2e8c53c3631c10bc4d92aea4a497886d21ea554f747c7666394e9b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5478062033653259}",,,,,,,,,,['neutral'],neutral,1 NCT00987389,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/lower-glucocorticoids-dosage-regimen-may-lower-risk-death-study/', 'title': 'Lower Dosage of Glucocorticoids May Decrease Risk of Death, Study Suggests', 'source': 'ANCA Vasculitis News', 'date': 'Mar 30, 2022', 'snippet': 'A reduced-dose regimen may lower the risk of death and serious infections, \nwhile not increasing the risk of kidney failure, in people with \nANCA-associated...', 'thumbnail': 'https://serpapi.com/searches/6723c5ad5a461a60b367dcd5/images/bb4c66ba6a4731d9b8740d8b9ade7bac39690bf38e420cc9427f2fbeeda97f02.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8226317763328552}",,,,,,,,,,['neutral'],neutral,1 NCT05154578,"{'position': 1, 'link': 'https://pf-media.co.uk/news/minervax-begins-phase-1-clinical-study-of-novel-gbs-vaccine/', 'title': 'MinervaX begins phase 1 clinical study of novel GBS vaccine', 'source': 'Pf Media', 'date': 'Apr 17, 2023', 'snippet': 'MinervaX has announced the first phase 1 clinical study in older adults of \nits novel vaccine for Group B Streptococcus.', 'thumbnail': 'https://serpapi.com/searches/6723c5da310300720f02786a/images/b8e1f01681792a61650b4cc32b5a86f825edf75c347db99a534aacf716036726.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8728817105293274}",,,,,,,,,,['neutral'],neutral,1 NCT03831971,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-test-experimental-drug-curb-opioid-cravings', 'title': 'NIH to test experimental drug to curb opioid cravings', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Mar 21, 2019', 'snippet': 'A clinical trial of an experimental drug designed to treat cravings \nassociated with opioid use disorder (OUD) has begun in the National \nInstitutes of Health...', 'thumbnail': 'https://serpapi.com/searches/6723c5ee59f91190a5e1e9f2/images/a5932992eae753f3b33c147654ec6bfd0bb0fdaa5b1cba311da17967514df655.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8840211033821106}",,,,,,,,,,['neutral'],neutral,1 NCT03745716,"{'position': 1, 'link': 'https://aml-hub.com/medical-information/efficacy-and-safety-of-eprenetapopt-apr-246-combined-with-azacitidine-in-patients-with-tp53-mutant-mds-and-oligoblastic-aml', 'title': 'Efficacy and safety of eprenetapopt (APR-246) combined with azacitidine in patients with TP53-mutant MDS and oligoblastic AML', 'source': 'aml-hub.com', 'date': 'Jan 5, 2022', 'snippet': 'Eprenetapopt (APR-246), a p53 reactivator, has recently demonstrated \npromising efficacy and safety in two phase II trials (NCT03072043 and \nNCT03588078) when...', 'thumbnail': 'https://serpapi.com/searches/6723c5eefcd69ee1d5dd53a6/images/2fb0b0fa13580cd03700c8003d144b93d59bd7ee078da1a72b316d109f33b26b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.742760956287384}","{'position': 2, 'link': 'https://www.ajmc.com/view/phase-3-trials-in-high-risk-mds-highlight-future-directions', 'title': 'Phase 3 Trials in High-Risk MDS Highlight Future Directions', 'source': 'AJMC', 'date': 'Dec 8, 2022', 'snippet': 'A recent review emphasizes a need for novel therapies, summarizes current \nphase 3 clinical trials, and suggests several considerations for...', 'thumbnail': 'https://serpapi.com/searches/6723c5eefcd69ee1d5dd53a6/images/2fb0b0fa13580cd0f1d02f7d3caa96d5d3e12f820a9d8d6d12084de44eb06e62.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8933826088905334}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02105636,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1602252', 'title': 'Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck', 'source': 'The New England Journal of Medicine', 'date': 'Oct 9, 2016', 'snippet': 'Treatment with nivolumab resulted in longer overall survival than treatment \nwith standard, single-agent therapy.', 'thumbnail': 'https://serpapi.com/searches/6723c61f6ad3c99a920eb1f1/images/c9a25a9f0baa6c116b7561ac98ea690fa42eba317eddf144a59d78be6f1f95a9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6905208230018616}",,,,,,,,,,['neutral'],neutral,1 NCT03230838,"{'position': 1, 'link': 'https://www.empr.com/home/news/zerbaxa-approved-for-complicated-pediatric-intra-abdominal-urinary-tract-infections/', 'title': 'Zerbaxa Approved for Complicated Pediatric Intra-abdominal, Urinary Tract Infections', 'source': 'Medical Professionals Reference', 'date': 'Apr 26, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved the supplemental New \nDrug Applications (sNDAs) for Zerbaxa (ceftolozane and tazobactam) to \ninclude...', 'thumbnail': 'https://serpapi.com/searches/6723c644749783a6b49d4986/images/b24ff181e9e0fd3e11af037319d023d89f1cb3c0274f3bbbaf114097d01f6d10.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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currently approved for the treatment \nof plaque psoriasis: guselkumab, risankizumab, and tildrakizumab.', 'thumbnail': 'https://serpapi.com/searches/6723c70ed364b4d16b1c5ecb/images/0dc444f390426e6e3f5dc24b79573d54ebbb83ee9ec0ab7ba23c17e8a07e8d49.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.890917956829071}",,,,,,,,,,['neutral'],neutral,1 NCT02552212,"{'position': 1, 'link': 'https://www.rheumatologyadvisor.com/news/certolizumab-pegol-demonstrates-positive-results-in-phase-3-trial-for-nonradiographic-axial-spondyloarthritis/', 'title': 'Certolizumab Pegol Demonstrates Positive Results in Phase 3 Trial for Nonradiographic Axial Spondyloarthritis', 'source': 'Rheumatology Advisor', 'date': 'May 17, 2018', 'snippet': 'Results from a phase 3 placebo-controlled study show that CIMZIA® \n(certolizumab pegol) improves the signs and symptoms of nonradiographic \naxial...', 'thumbnail': 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'https://alzheimersnewstoday.com/news/fda-places-full-hold-clinical-testing-cortexyme-cor388-alzheimers/', 'title': 'FDA Puts Full Hold on Clinical Testing of Cortexyme’s COR388', 'source': ""Alzheimer's News Today"", 'date': 'Feb 7, 2022', 'snippet': ""The U.S. Food and Drug Administration placed a full clinical hold on \nCOR388, an oral therapy from Cortexyme for Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/6723c71a48c97dd4ce243693/images/df045440e007bd7683775d6f35b2587d063d9adc08643f41c338c05a45f78e08.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8587650060653687}","{'position': 2, 'link': 'https://alzheimersnewstoday.com/news/cortexyme-gain-trial-atuzaginstat-potential-benefit-alzheimers-patients-severe-gum-disease/', 'title': 'Atuzaginstat Shows Potential in GAIN Trial Patients With Severe Gum Disease', 'source': ""Alzheimer's News Today"", 'date': 'Nov 2, 2021', 'snippet': 'Treatment with atuzaginstat (COR388) appeared to slow their cognitive \ndecline, according to results from the Phase 2/3 GAIN clinical trial.', 'thumbnail': 'https://serpapi.com/searches/6723c71a48c97dd4ce243693/images/df045440e007bd7641bb8f47c7774d312892cb800111e48dfb0f200e96d75d30.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8065990805625916}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03824392,"{'position': 1, 'link': 'https://sarcoidosisnews.com/news/benefits-seen-efzofitimod-pulmonary-sarcoidosis-treatment-trial/', 'title': '1st in class aTyr treatment shows promise in pulmonary sarcoidosis...', 'source': 'Sarcoidosis News', 'date': 'Jun 14, 2023', 'snippet': 'Efzofitimod has shown promise as a pulmonary sarcoidosis treatment in a \nclinical trial, with more exposure linked to better lung function.', 'thumbnail': 'https://serpapi.com/searches/6723c74c5bb6a2a99227b1dd/images/5a8fdf0134badae28a4ab3b2b6f74aa316d20e9cf3a457899c5b6f8b7eae4915.png', 'sentiment': 'positive', 'sentiment_prob': 0.8347368836402893}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/novel-immunomodulator-gets-orphan-drug-status-for-sarcoidosis/', 'title': 'Novel Immunomodulator Gets Orphan Drug Status for Sarcoidosis', 'source': 'Medical Professionals Reference', 'date': 'Jan 6, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted Orphan Drug designation \nto ATYR1923 for the treatment of sarcoidosis.', 'thumbnail': 'https://serpapi.com/searches/6723c74c5bb6a2a99227b1dd/images/5a8fdf0134badae247cdf78aab85321d4bdcc6d7da54bf3f5d4cb62486ca55a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8696157336235046}","{'position': 3, 'link': 'https://sarcoidosisnews.com/news/experimental-pulmonary-sarcoidosis-treatment-efzofitimod-fast-track/', 'title': 'Experimental Pulmonary Sarcoidosis Treatment Efzofitimod on Fast Track', 'source': 'Sarcoidosis News', 'date': 'Aug 12, 2022', 'snippet': ""Efzofitimod, an experimental treatment for pulmonary sarcoidosis that's set \nto begin Phase 3 clinical testing later this year, has been granted fast \ntrack..."", 'thumbnail': 'https://serpapi.com/searches/6723c74c5bb6a2a99227b1dd/images/5a8fdf0134badae26c89ad77302316c26bf5085df9cec31307788d3998f1cde6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8707942962646484}",,,,,,,,"['positive', 'neutral', 'neutral']",neutral,1 NCT02260505,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/6-year-imatinib-maintenance-therapy-reduces-recurrence-risk-in-gist', 'title': 'Six-Year Imatinib Maintenance Therapy Reduces Recurrence Risk in GIST', 'source': 'Cancer Network', 'date': 'May 9, 2024', 'snippet': 'Investigators found that imatinib maintenance therapy for 6 years reduced \nthe risk of recurrence in patients with gastrointestinal stromal...', 'thumbnail': 'https://serpapi.com/searches/6723c751213c87b600cd7e16/images/f8a1128d2286f93df8abc5f2d10920802fc5c8921e9b62e04ba17563b604ebf1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8645538687705994}",,,,,,,,,,['neutral'],neutral,1 NCT00287729,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/pirfenidone-may-be-effective-for-improving-exercise-capacity-dyspnea-in-idiopathic-pulmonary-fibrosis/', 'title': 'Pirfenidone May Be Effective for Improving Exercise Capacity, Dyspnea in Idiopathic Pulmonary Fibrosis', 'source': 'Pulmonology Advisor', 'date': 'Oct 10, 2018', 'snippet': 'When treated with pirfenidone, patients with idiopathic pulmonary fibrosis \nexperienced significant improvements in 6-minute walking distance...', 'thumbnail': 'https://serpapi.com/searches/6723c758be8013a061929cbd/images/489f3f01c5ce0177f9a5af7c82c7e100393a8d54e09a75a82a127a42d047f3fe.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5335983633995056}",,,,,,,,,,['positive'],positive,1 NCT06006871,"{'position': 1, 'link': 'https://www.researchgate.net/figure/IDEAL-Games-framework-22-adapted-to-create-a-general-guide-for-game-based-attention_fig1_362409691', 'title': 'Figure 1. IDEAL-Games framework [22] adapted to create a general guide...', 'source': 'ResearchGate', 'date': 'May 5, 2023', 'snippet': 'Video game–based therapeutic interventions have demonstrated some \neffectiveness in decreasing the symptoms of attention deficit hyperactivity \ndisorder...', 'thumbnail': 'https://serpapi.com/searches/6723c766ec5410e2f56ef64b/images/54942d71fd92605410b4e794efee4a2a8d4cc5636db5cf7541a1e0d312512c9c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8364045023918152}",,,,,,,,,,['neutral'],neutral,1 NCT00097032,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/cognitive-functioning-acute-sedative-effects-risperidone/', 'title': 'Cognitive Functioning and Acute Sedative Effects of Risperidone and Quetiapine in Patients With Stable Bipolar I Disorder: A Randomized, Double-Blind, Crossover Study', 'source': 'Psychiatrist.com', 'date': 'Aug 15, 2007', 'snippet': 'The results indicate that initiation of quetiapine treatment was associated \nwith more immediate adverse cognitive effects and increased somnolence \nthan...', 'thumbnail': 'https://serpapi.com/searches/6723c79d24079331fb3a7195/images/38d8d3eb2816b406d40cb4c2b11e8539f344d668bc18c2c5479e44a246b81a32.png', 'sentiment': 'neutral', 'sentiment_prob': 0.814086377620697}",,,,,,,,,,['neutral'],neutral,1 NCT03548220,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/mitapivat-safely-increases-hemoglobin-levels-in-patients-early-data-phase-1-trial/', 'title': 'SCD Trial Shows Mitapivat Safely Boosts Hemoglobin Levels in Patients', 'source': 'Sickle Cell Disease News', 'date': 'Jun 25, 2020', 'snippet': 'Early Phase 1 trial results show mitapivat safely increases hemoglobin \nlevels and lowers red blood cell damage in adults with sickle cell...', 'thumbnail': 'https://serpapi.com/searches/6723c7bb63a844cecdffced1/images/eb194d649512c70d2cd098e64fdf41ebdffd1448fd5f55a5f9965e3d53665b46.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5431870222091675}",,,,,,,,,,['neutral'],neutral,1 NCT02728843,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-022-00345-4', 'title': 'Empirical evidence for biometal dysregulation in Parkinson’s disease from a systematic review and Bradford Hill analysis', 'source': 'Nature', 'date': 'Jun 27, 2022', 'snippet': ""The available evidence supports an etiological role for iron and copper \ndysregulation in Parkinson's disease, substantiating current clinical \ntrials."", 'thumbnail': 'https://serpapi.com/searches/6723c7cbcaddc3538c85522d/images/d964a67ac740af89894bae9427c3dd039a92e87acfe146f4c55e3cc3a2b6ea10.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8967313766479492}",,,,,,,,,,['neutral'],neutral,1 NCT03703102,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/amgen-and-kyowa-kirin-present-positive-late-breaking-data-from-phase-2-study-of-amg-451khk4083-in-adult-patients-with-moderate-to-severe-atopic-dermatitis-at-eadv-congress-301391185.html', 'title': 'Amgen And Kyowa Kirin Present Positive Late-Breaking Data From Phase 2 Study Of AMG 451/KHK4083 In Adult Patients With Moderate-to-Severe Atopic Dermatitis At EADV Congress', 'source': 'PR Newswire', 'date': 'Oct 2, 2021', 'snippet': 'AMG 451/KHK4083 is a potential first-in-class anti-OX40 fully human \nmonoclonal antibody in development for the treatment of moderate-to-severe \natopic...', 'thumbnail': 'https://serpapi.com/searches/6723c7dcb28e6b4a1f154121/images/bfcd0ee47ed62d082aee7d4208982c2ae3149d0720cd70a32e1f00e526a0ec54.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7533566951751709}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/amgen-to-showcase-new-data-from-inflammation-portfolio-at-eadv-virtual-congress-2021-301375267.html', 'title': 'Amgen To Showcase New Data From Inflammation Portfolio At EADV Virtual Congress 2021', 'source': 'PR Newswire', 'date': 'Sep 13, 2021', 'snippet': '32 Week Data From the Phase 3 ADVANCE Trial Investigating the Safety and \nEfficacy of Otezla to Improve Mild-to-Moderate Plaque Psoriasis...', 'thumbnail': 'https://serpapi.com/searches/6723c7dcb28e6b4a1f154121/images/bfcd0ee47ed62d08b7bf634a16965770d78844b55670721d21efa571b8b9ad23.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8882607221603394}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00118274,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-46877-6', 'title': 'Multipeptide vaccines for melanoma in the adjuvant setting: long-term survival outcomes and post-hoc analysis of a randomized phase II trial', 'source': 'Nature', 'date': 'Mar 22, 2024', 'snippet': 'The critical roles of CD4+ T cells have been understudied for cancer \nvaccines. Here we report long-term clinical outcomes of a randomized...', 'thumbnail': 'https://serpapi.com/searches/6723c7e0d771bdcb8c631f05/images/3f5ce838ffb7b191d0ebbf4f1982a4f05b8cc474189bef69aa323652adf79bcc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9029699563980103}",,,,,,,,,,['neutral'],neutral,1 NCT01531361,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-022-00341-0', 'title': 'BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study | npj Precision Oncology', 'source': 'Nature', 'date': 'Feb 18, 2023', 'snippet': 'We performed a pooled analysis of four phase one studies evaluating the \nsafety and efficacy of vemurafenib monotherapy and vemurafenib combined \nwith targeted...', 'thumbnail': 'https://serpapi.com/searches/6723c83ab6a79cfdeda5b3ed/images/324164902ca70f6f4ca57f5297ff5539e3e7fe00d48be9394b22bae591402fc6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9065907597541809}",,,,,,,,,,['neutral'],neutral,1 NCT01471444,"{'position': 1, 'link': 'https://www.nature.com/articles/s41409-022-01705-7', 'title': 'A randomized phase III study of pretransplant conditioning for AML/MDS with fludarabine and once daily IV busulfan ± clofarabine in allogeneic stem cell transplantation', 'source': 'Nature', 'date': 'May 24, 2022', 'snippet': 'Pretransplant conditioning with Fludarabine (Flu)-Busulfan (Bu) is safe, \nbut clofarabine (Clo) has improved antileukemic activity.', 'thumbnail': 'https://serpapi.com/searches/6723c88a657c66b440e30352/images/2339f6a2fcb444d89f7f18eb8812032a76158588ce87a3625b785f14465f498a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.774931013584137}",,,,,,,,,,['neutral'],neutral,1 NCT03186781,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-021-01660-8', 'title': 'Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial', 'source': 'Nature', 'date': 'Feb 3, 2022', 'snippet': 'Currently, licensed seasonal influenza vaccines display variable vaccine \neffectiveness, and there remains a need for novel vaccine platforms...', 'thumbnail': 'https://serpapi.com/searches/6723c89298fad6961dd80955/images/c7a8b0a64bc71050358ee8fef439b73ec86819b311399ac8a9ffda7138a47230.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8805010914802551}",,,,,,,,,,['neutral'],neutral,1 NCT03382405,"{'position': 1, 'link': 'https://journals.asm.org/doi/10.1128/jvi.01603-23', 'title': 'Characterization of humoral and cellular immunologic responses to an mRNA-based human cytomegalovirus vaccine from a phase 1 trial of healthy adults', 'source': 'ASM Journals', 'date': 'Mar 25, 2024', 'snippet': 'mRNA-1647 is an investigational mRNA-based vaccine against cytomegalovirus \n(CMV) that contains sequences encoding the CMV proteins glycoprotein B and \npentamer.', 'thumbnail': 'https://serpapi.com/searches/6723c92148c429c80104c11e/images/f287a8a77578335b94e6f780c844d858444c3f00c0b630411d68f7fc283bd14f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9078482985496521}",,,,,,,,,,['neutral'],neutral,1 NCT01910012,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-017-10542-4', 'title': 'A Phase II Study of Arginine Deiminase (ADI-PEG20) in Relapsed/Refractory or Poor-Risk Acute Myeloid Leukemia Patients', 'source': 'Nature', 'date': 'Sep 12, 2017', 'snippet': 'Exogenous arginine is required for growth in some argininosuccinate \nsynthetase (ASS)-deficient cancers. Arginine deiminase (ADI) inhibits...', 'thumbnail': 'https://serpapi.com/searches/6723c940708e2e6934b543b7/images/00d84f7cd576268d220a364a81d95efefc2904a51b1b13fecdeb3821be381cc9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8377330303192139}",,,,,,,,,,['neutral'],neutral,1 NCT01159028,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332220301888', 'title': 'RNA-based pharmacotherapy for tumors: From bench to clinic and back', 'source': 'ScienceDirect.com', 'date': 'Feb 14, 2020', 'snippet': 'RNA therapy is a treatment that regulates cell proteins and cures diseases \nby affecting the metabolism of mRNAs in cells.', 'thumbnail': 'https://serpapi.com/searches/6723c8a80f1a336e05f57ab7/images/8d23c03105862d0b51381c35cea17ef430638d7efb60ffdaaaf0fa5d2e4566e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7626101970672607}",,,,,,,,,,['neutral'],neutral,1 NCT00787059,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/joim.13308', 'title': 'Gene therapy for ischaemic heart disease and heart failure - Korpela - 2021 - Journal of Internal Medicine', 'source': 'Wiley Online Library', 'date': 'May 25, 2021', 'snippet': 'Gene therapy has been expected to become a novel treatment method since the \nstructure of DNA was discovered in 1953.', 'thumbnail': 'https://serpapi.com/searches/6723c8afa5e502a8e8204c0e/images/9aff288308d711348f2d332617f960ab08a2d639ea180cf4a95e4b5ba2dab81b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7769891619682312}",,,,,,,,,,['neutral'],neutral,1 NCT02861534,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1915928', 'title': 'Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction', 'source': 'The New England Journal of Medicine', 'date': 'Mar 28, 2020', 'snippet': 'The effect of vericiguat, a novel oral soluble guanylate cyclase \nstimulator, in patients with heart failure and reduced ejection fraction \nwho had recently...', 'thumbnail': 'https://serpapi.com/searches/6723c8bdd364b4d1b56f8c17/images/b1ff0fcdc5cf4dc96553d44282629f05d1db6bbee0a8ca28bdc755ee74196d70.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8445867896080017}",,,,,,,,,,['neutral'],neutral,1 NCT05596734,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1412478/full', 'title': 'Towards broad-spectrum protection: the development and challenges of combined respiratory virus vaccines', 'source': 'Frontiers', 'date': 'Jun 29, 2024', 'snippet': 'This review delves into the major advancements in the field of combined \nvaccine research, underscoring the strategic use of various platforms.', 'thumbnail': 'https://serpapi.com/searches/6723c8e9861b9d38e4f1e35d/images/1df0ac5edd14a931aaa2a319db32ce3801f29c843c8c5e571dc4e2baa9fb65fa.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5735475420951843}",,,,,,,,,,['positive'],positive,1 NCT05397119,"{'position': 1, 'link': 'https://pubs.acs.org/doi/10.1021/acsnano.3c10797', 'title': 'Nanoplatform Based Intranasal Vaccines: Current Progress and Clinical Challenges', 'source': 'ACS Publications', 'date': 'Aug 26, 2024', 'snippet': 'Multiple vaccine platforms have been employed to develop the nasal \nSARS-CoV-2 vaccines in preclinical studies, and the dominating pipelines...', 'thumbnail': 'https://serpapi.com/searches/6723c8ec8d0417cf92184f09/images/b3cce3728694140faa7d7a65ca924eb111f4ed0699dc3561d356cd231115ab75.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8946354389190674}",,,,,,,,,,['neutral'],neutral,1 NCT00781742,"{'position': 1, 'link': 'https://www.psychiatrictimes.com/view/ketamine-induced-optimism-new-hope-development-rapid-acting-antidepressants', 'title': 'Ketamine-Induced Optimism: New Hope for the Development of Rapid-Acting Antidepressants', 'source': 'Psychiatric Times', 'date': 'Jul 13, 2012', 'snippet': 'There is rapidly escalating interest in drugs that target the glutamatergic \nneurotransmitter system, especially NMDA receptor modulators.', 'thumbnail': 'https://serpapi.com/searches/6723c8f44a4a1daf8986358b/images/9157f2d8b536fe5a756d7fb53865b1ed790969c0de1ea6286f867d698c1779c7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.798674464225769}",,,,,,,,,,['positive'],positive,1 NCT04208958,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01522-4', 'title': 'Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends', 'source': 'Nature', 'date': 'Aug 28, 2023', 'snippet': 'Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, \nand PD-L1, novel targeting LAG-3 drugs have also been approved...', 'thumbnail': 'https://serpapi.com/searches/6723c8f7163bdf5e17e18aaa/images/ff3741126700dd2e758b5850e97bfca4609e3a878bc05879d30f0616ae8fae48.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9091306924819946}",,,,,,,,,,['neutral'],neutral,1 NCT05033886,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/astellas-fezolinetant-reduces-frequency-and-severity-of-vms-associated-with-menopause-in-women-considered-unsuitable-for-hormone-therapy-302001281.html', 'title': ""Astellas' Fezolinetant Reduces Frequency and Severity of VMS Associated with Menopause in Women Considered Unsuitable for Hormone Therapy"", 'source': 'PR Newswire', 'date': 'Nov 29, 2023', 'snippet': 'Phase 3b DAYLIGHT study being presented at ESG 2023 demonstrated \nfezolinetant 45 mg achieved statistically significant reductions in the...', 'thumbnail': 'https://serpapi.com/searches/6723c8f71f3d4b4cf1a9fd7b/images/1d1dc7d957c59c2974e4f74112ba88058922b605d26481840a98d21fefae53c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7966688275337219}",,,,,,,,,,['neutral'],neutral,1 NCT00000389,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-34938-7', 'title': 'The difference between ‘placebo group’ and ‘placebo control’: a case study in psychedelic microdosing', 'source': 'Nature', 'date': 'Jul 26, 2023', 'snippet': ""In medical trials, 'blinding' ensures the equal distribution of expectancy \neffects between treatment arms in theory; however, blinding often..."", 'thumbnail': 'https://serpapi.com/searches/6723c8f9059caf650f19c45b/images/705bbfbc027f4abddf4b31419d1e83000aef3f55a4a8779b518f605dc66e4c37.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9171350598335266}",,,,,,,,,,['neutral'],neutral,1 NCT03915470,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/destiny-pharma-research-treating-mrsa-infections-cf-xf-73/', 'title': 'Destiny Pharma Will Research Treating MRSA Infections in CF With XF-73', 'source': 'Cystic Fibrosis News Today', 'date': 'Jul 14, 2022', 'snippet': 'Destiny Pharma received a Cystic Fibrosis Foundation award to research \ntreating MRSA infections with the investigational compound XF-73.', 'thumbnail': 'https://serpapi.com/searches/6723c959358539e88f8212e6/images/de5c6c21e79e5734c1b29fa4d6cb05d2276d25229acfb51e31497562ed19ee2b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.854690432548523}",,,,,,,,,,['neutral'],neutral,1 NCT03959488,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2110275', 'title': 'Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants', 'source': 'The New England Journal of Medicine', 'date': 'Mar 2, 2022', 'snippet': 'Respiratory syncytial virus (RSV) is a major cause of lower respiratory \ntract infection and hospitalization in infants.', 'thumbnail': 'https://serpapi.com/searches/6723c96fb9458db70e908458/images/4b61eee0033ffc943ae0bf853f4607de43fbfdd3de9219347ae07516881fc049.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6536106467247009}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMc2112186', 'title': 'Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity', 'source': 'The New England Journal of Medicine', 'date': 'Mar 2, 2022', 'snippet': 'Nirsevimab is a monoclonal antibody targeting respiratory syncytial virus. \nIn this trial, the safety of nirsevimab was assessed in infants...', 'thumbnail': 'https://serpapi.com/searches/6723c96fb9458db70e908458/images/4b61eee0033ffc943bed07d247d63ebc535bf35e68b2cce07ca448245bf8f430.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8949854373931885}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT01817166,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/09/20/ectrims-2024-high-dose-vitamin-d-delay-progression-ms/', 'title': 'ECTRIMS 2024: High-dose vitamin D can help delay progression to MS', 'source': 'Multiple Sclerosis News Today', 'date': '1 month ago', 'snippet': 'High-dose cholecalciferol (vitamin D) is safe and can nearly double the \ntime it takes for clinically isolated syndrome to progress to MS.', 'thumbnail': 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in TKIs May Sway Choice of First-Line Therapy in ALK+ NSCLC', 'source': 'Targeted Oncology', 'date': 'May 21, 2024', 'snippet': 'Both brigatinib and [alectinib], and even lorlatinib, are superior to \ncrizotinib and they are all acceptable frontline options, with subtle \ndifferences between...', 'thumbnail': 'https://serpapi.com/searches/6723c980aab36de635619ceb/images/0898b36e57dc3a51c36702ab4b1e3a7d3b42f79f7bd7411f9f595ecd296cf218.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7617494463920593}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04773587,"{'position': 1, 'link': 'https://www.medcentral.com/dermatology/fda-approves-non-steroidal-roflumilast-cream-for-atopic-dermatitis', 'title': 'FDA Approves Non-Steroidal Roflumilast Cream for Atopic Dermatitis', 'source': 'MedCentral', 'date': 'Jul 9, 2024', 'snippet': 'The US Food and Drug Administration (FDA) approved Zoryve (roflumilast \n0.15% cream, Arcutis Biotherapeutics) for adults and children aged 6 years \nand older...', 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reports that oxaliplatin, a chemo agent, does not increase the risk \nof neuropathy in patients carrying uncommon variants in...', 'thumbnail': 'https://serpapi.com/searches/6723cb4bf41044ef14218938/images/a37cf1e19832c2245b7c5f31ea10717e69f20cb18d86413d9cb62d510b025cc0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8533989787101746}",,,,,,,,,,['neutral'],neutral,1 NCT03844386,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1155/2024/2147912', 'title': 'The Question of HIV Vaccine: Why Is a Solution Not Yet Available? - Libera - 2024 - Journal of Immunology Research', 'source': 'Wiley Online Library', 'date': 'Apr 8, 2024', 'snippet': 'Ever since its discovery, human immunodeficiency virus type 1 (HIV-1) \ninfection has remained a significant public health concern.', 'thumbnail': 'https://serpapi.com/searches/6723cb60c05eb51be919d944/images/54162ff205ac858befd3af8fbd9c1a1ae9a54bd859064772b26aca33925afe14.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'On December 1, 2022, the IDH1 inhibitor olutasidenib was approved for the \ntreatment of adults with relapsed or refractory acute myeloid...', 'thumbnail': 'https://serpapi.com/searches/6723cb86fab27313b26fb0bf/images/56a6825ad17595b42ab507d837b6b9a3e2e8b3e67cccd69672bab1062436de30.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8930202722549438}",,,,,,,,,,['neutral'],neutral,1 NCT03020771,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S2405844021022647', 'title': 'Development of a protective inactivated vaccine against Crimean–Congo hemorrhagic fever infection', 'source': 'ScienceDirect.com', 'date': 'Oct 13, 2021', 'snippet': 'In this study, we showed that cell-culture-purified and \nformalin-inactivated vaccine candidates induced strong and robust immunity \nin vaccinated mice dose-...', 'thumbnail': 'https://serpapi.com/searches/6723cbaa07c7bee603a27463/images/24fb63b58c39a474297551e272659153683bf0ae1802fa9dfad62bd33daeacc3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6813912987709045}",,,,,,,,,,['neutral'],neutral,1 NCT05713318,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-40933-3', 'title': 'An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants', 'source': 'Nature', 'date': 'Aug 25, 2023', 'snippet': 'Many of the currently available COVID-19 vaccines and therapeutics are not \neffective against newly emerged SARS-CoV-2 variants.', 'thumbnail': 'https://serpapi.com/searches/6723cbcea5d702aba6fc5e6f/images/01fc61c8a857c5a3f9bb12dd36e3a38e32a04dd1b6fd99f42e9d7b9c32836d7b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5404082536697388}",,,,,,,,,,['neutral'],neutral,1 NCT02954458,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/jpn3.12276', 'title': 'Long-term teduglutide associated with improved response in pediatric short bowel syndrome-associated intestinal failure', 'source': 'Wiley Online Library', 'date': 'Jun 14, 2024', 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(prothrombin complex concentrate, human-lans; marketed in Europe \nand Canada as octaplex) has received US Food and Drug Administration (FDA) \napproval.', 'thumbnail': 'https://serpapi.com/searches/6723d03de281ee6aff8fcf70/images/384c7e5c7e14b835b179cbdc74d2e231f2cafeda1dff3d66d03b73f0d703ae43.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6028887629508972}","{'position': 3, 'link': 'https://www.thepharmaletter.com/biotechnology/fda-green-light-for-octapharma-s-balfaxar', 'title': ""FDA green light for Octapharma's Balfaxar"", 'source': 'The Pharma Letter', 'date': 'Jul 26, 2023', 'snippet': 'More on this story... Swiss firm spreads tentacles with US rare disease \napproval · Biotechnology · Swiss firm spreads tentacles with US rare...', 'thumbnail': 'https://serpapi.com/searches/6723d03de281ee6aff8fcf70/images/384c7e5c7e14b83548afd8bfcd8eca572114bc7360b24a7411259945a83816de.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9057815670967102}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04419467,"{'position': 1, 'link': 'https://www.nature.com/articles/s41420-023-01304-5', 'title': 'Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response | Cell Death Discovery', 'source': 'Nature', 'date': 'Jan 16, 2023', 'snippet': 'The pathogenesis of diabetic kidney disease (DKD) is complicated. Current \nclinical treatments fail to achieve satisfactory efficacy in the...', 'thumbnail': 'https://serpapi.com/searches/6723d049fcd69ee1d5dd5740/images/d1c88ec6c328f3bd8f711d15fb85295d2c7a5f8fdf84145631361530b5f1a4ee.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.517368495464325}",,,,,,,,,,['negative'],negative,0 NCT05642546,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/fda-clears-phase-2-trial-antibody-therapy-ruxoprubart-aav/', 'title': 'FDA clears Phase 2 trial of antibody therapy ruxoprubart in AAV', 'source': 'ANCA Vasculitis News', 'date': 'Jun 24, 2024', 'snippet': 'The US Food and Drug Administration (FDA) has given NovelMed the green \nlight to initiate a Phase 2 clinical trial to test its investigational \nantibody-based...', 'thumbnail': 'https://serpapi.com/searches/6723d04e7b05ca0e36f00a7e/images/d9f81c54e17ae5cf19bd2ba05b9636073da9cae91efd4f7a0225a9aa11937507.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7502970099449158}",,,,,,,,,,['neutral'],neutral,1 NCT03882970,"{'position': 1, 'link': 'https://www.renalandurologynews.com/news/tirzepatide-vs-semaglutide-lower-metabolic-syndrome-prevalence/', 'title': 'Tirzepatide vs Semaglutide Linked to Lower Metabolic Syndrome Prevalence', 'source': 'Renal and Urology News', 'date': 'Apr 12, 2024', 'snippet': 'Use of tirzepatide, compared with placebo, semaglutide, and insulin \ndegludec and glargine, is associated with a lower prevalence of metabolic \nsyndrome among...', 'thumbnail': 'https://serpapi.com/searches/6723d05b88bcde1b95c7c7c1/images/40b3520352c2c696925b14dc867c6224588ace432322cdc1b4655108b4a00f20.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8086218237876892}",,,,,,,,,,['neutral'],neutral,1 NCT02289950,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/morphotek-and-eurofarma-laboratorios-sa-sign-exclusive-licensing-agreement-for-farletuzumab-in-latin-america-300337215.html', 'title': 'Morphotek and Eurofarma Laboratórios S.A. Sign Exclusive Licensing Agreement for Farletuzumab in Latin America', 'source': 'PR Newswire', 'date': 'Oct 3, 2016', 'snippet': 'PRNewswire/ -- Morphotek®, Inc., a subsidiary of Eisai Inc., announced \ntoday that it signed an exclusive licensing agreement with Eurofarma...', 'thumbnail': 'https://serpapi.com/searches/6723d05b5809e735b9893e87/images/79752ef603ec51c8083cfc880de6ba62eaad6d9acfc00d67ddb1c2c6c062a0a2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9180112481117249}",,,,,,,,,,['neutral'],neutral,1 NCT04123561,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223016177', 'title': 'Harnessing the multifunctionality of lipid-based drug delivery systems for the local treatment of osteoarthritis', 'source': 'ScienceDirect.com', 'date': 'Nov 7, 2023', 'snippet': 'This review emphasizes recent advancements in lipid-based drug delivery \nsystems (DDSs) for intra-articular administration of OA therapeutics.', 'thumbnail': 'https://serpapi.com/searches/6723cfa79f8bfc1ce81120da/images/4791edeaaa67385508e96f2a2fb8056daf61675d2222628acf61ab2307c6a730.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.650626003742218}",,,,,,,,,,['neutral'],neutral,1 NCT03019419,"{'position': 1, 'link': 'https://alsnewstoday.com/news/study-evaluating-perampanel-als-stopped-adverse-events/', 'title': 'Study Evaluating Perampanel in ALS Stopped Due to Adverse Events', 'source': 'ALS News Today', 'date': 'Nov 9, 2021', 'snippet': 'A small open-label study evaluating the epilepsy medication perampanel in \nadults with amyotrophic lateral sclerosis (ALS) was halted due to adverse \nevents that...', 'thumbnail': 'https://serpapi.com/searches/6723cfea51d84d25a324b51a/images/fe990e2914cd6d4a85e418fb0706b572eca0b3d09546ee10aa3e35577cefd097.png', 'sentiment': 'negative', 'sentiment_prob': 0.5237719416618347}",,,,,,,,,,['negative'],negative,0 NCT02256917,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/fda-approves-new-vial-strengths-for-hemophilia-a-therapy-nuwiq/', 'title': 'Hemophilia A Therapy Nuwiq to Come in New Vial Strengths in U.S.', 'source': 'Hemophilia News Today', 'date': 'Aug 28, 2017', 'snippet': ""The US Food and Drug Administration has approved new vial strengths for \nOctopharma's hemophilia A therapy Nuwiq, which means patients will need \nfewer vials per..."", 'thumbnail': 'https://serpapi.com/searches/6723cffcc82127187f68d3db/images/800e297b534a0b92bb28686d370472b4f38429f41c90a9431d84ef276bb3942a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8386752605438232}",,,,,,,,,,['neutral'],neutral,1 NCT05054621,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-33146-7', 'title': 'A randomized controlled trial of heterologous ChAdOx1 nCoV-19 and recombinant subunit vaccine MVC-COV1901 against COVID-19', 'source': 'Nature', 'date': 'Sep 17, 2022', 'snippet': 'Heterologous prime-boost COVID-19 vaccine strategy may facilitate mass \nCOVID-19 immunization. We reported early immunogenicity and safety...', 'thumbnail': 'https://serpapi.com/searches/6723d063d111956b07a12e7c/images/526e8275acf053841a09bed1b67c3ea91c26471549c7e70b30e0e71696c7c242.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8337039947509766}",,,,,,,,,,['neutral'],neutral,1 NCT04994483,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/topline-results-phase-3-studies-simufilam-alzheimers-due-this-year/', 'title': 'Topline results from Phase 3 trial of simufilam due this year', 'source': ""Alzheimer's News Today"", 'date': 'Feb 8, 2024', 'snippet': ""Two Phase 3 clinical trials are testing the effectiveness of simufilam, an \nexperimental oral therapy that's designed to improve cognition in people \nwith..."", 'thumbnail': 'https://serpapi.com/searches/6723d09fdb3ac9f357ce4602/images/dfc826cc872839a4db402e1ff9227951228bb7cf0640f6b3584499246f10bc4c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5712019801139832}","{'position': 2, 'link': 'https://alzheimersnewstoday.com/news/simufilam-found-safe-review-ongoing-alzheimers-drug-trials/', 'title': 'Simufilam found safe in review of ongoing Alzheimer’s clinical trials', 'source': ""Alzheimer's News Today"", 'date': '1 month ago', 'snippet': 'an independent safety monitoring board has recommended the continuation — \nwithout modifications — of two ongoing Phase 3 clinical trials testing...', 'thumbnail': 'https://serpapi.com/searches/6723d09fdb3ac9f357ce4602/images/dfc826cc872839a43c3a8df11b23eb249879dbb8eed286bf82bfab5bf30ad969.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6725298762321472}","{'position': 3, 'link': 'https://alzheimersnewstoday.com/news/simufilam-aid-cognition-alzheimers-patients-phase-2-study/', 'title': 'Simufilam aids cognition in 47% of Alzheimer’s patients in Phase 2 study', 'source': ""Alzheimer's News Today"", 'date': 'Mar 14, 2023', 'snippet': ""Cognitive benefits were reported in nearly half of the Alzheimer's disease \npatients given simufilam for one year in a clinical trial."", 'thumbnail': 'https://serpapi.com/searches/6723d09fdb3ac9f357ce4602/images/dfc826cc872839a4407e5a5294e09315a639fa4932025b5f6e8788c66056eed4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5083126425743103}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03209973,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01600-7', 'title': 'Long-term survival benefit of anti-PD-1 therapy in patients with relapsed or refractory classical Hodgkin lymphoma', 'source': 'Nature', 'date': 'Sep 20, 2023', 'snippet': 'Anti-programmed cell death-1 (anti-PD-1) therapies have shown a favorable \nefficacy and good tolerance for relapsed or refractory (r/r) classical \nHodgkin...', 'thumbnail': 'https://serpapi.com/searches/6723d0bf237938e78b848cf0/images/fd9d55a0884c5a58f845abe70e0e7474ed4476b4866edadfc3594ca231f7c090.png', 'sentiment': 'neutral', 'sentiment_prob': 0.668369472026825}",,,,,,,,,,['neutral'],neutral,1 NCT02949011,"{'position': 1, 'link': 'https://newsroom.uvahealth.com/2018/09/07/single-dose-drug-can-shorten-flu-symptoms-by-about-one-day-studies-suggest/', 'title': 'Single-Dose Drug Can Shorten Flu Symptoms By About a Day, Studies Suggest', 'source': 'UVA Health Newsroom', 'date': 'Sep 7, 2018', 'snippet': 'A single dose of a new influenza drug can significantly shorten the \nduration of the illness in teens and adults, according to a study...', 'thumbnail': 'https://serpapi.com/searches/6723d0c0d78a98c1c8871b32/images/7477fa5904c09083b15df98eedcec3e1dcffc4dfba4988a8cafe64627e80759e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7333375215530396}",,,,,,,,,,['neutral'],neutral,1 NCT02184195,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1903387', 'title': 'Maintenance Olaparib for Germline BRCA -Mutated Metastatic Pancreatic Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 2, 2019', 'snippet': 'Patients with a germline BRCA1 or BRCA2 mutation make up a small subgroup \nof those with metastatic pancreatic cancer. The poly(adenosine \ndiphosphate–ribose)...', 'thumbnail': 'https://serpapi.com/searches/6723d0dae1c27684e5a6509c/images/0c4abf085cb0cd5d5b0a599a5638a28a6d4e4d75cb74437b70f1772c90881b61.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7973864674568176}",,,,,,,,,,['neutral'],neutral,1 NCT00004125,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0707056', 'title': 'Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Apr 17, 2008', 'snippet': 'Weekly paclitaxel after standard adjuvant chemotherapy with doxorubicin and \ncyclophosphamide improves disease-free and overall survival in women with \nbreast...', 'thumbnail': 'https://serpapi.com/searches/6723d0dd49ea55e48af25255/images/44b08bc6175c48abad8e01379d046bf496f25ca386d8c800fcb071ec683c3d3a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.584206223487854}",,,,,,,,,,['neutral'],neutral,1 NCT02392559,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2019910', 'title': 'Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia', 'source': 'The New England Journal of Medicine', 'date': 'Aug 29, 2020', 'snippet': 'In this trial involving pediatric patients with familial \nhypercholesterolemia, evolocumab reduced the LDL cholesterol level and \nother lipid variables.', 'thumbnail': 'https://serpapi.com/searches/6723d0e729e6fb4ffa08bf5a/images/0ee6478a78446f2b6b018a8a5d6fab5b8c7ef516f777758c229ef090d495ffc2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.830830991268158}","{'position': 2, 'link': 'https://www.empr.com/home/news/repatha-approved-for-younger-patients-with-hefh-and-hofh/', 'title': 'Repatha Approved for Younger Patients with HeFH and HoFH', 'source': 'Medical Professionals Reference', 'date': 'Sep 27, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Repatha (evolocumab) \ninjection as an adjunct to diet and other low-density lipoprotein \ncholesterol (LDL-C)-...', 'thumbnail': 'https://serpapi.com/searches/6723d0e729e6fb4ffa08bf5a/images/0ee6478a78446f2bd5d6b16a7cd5e6217fec0aec6ba393f1f375c8caae6d5041.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7352215647697449}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04465955,"{'position': 1, 'link': 'https://www.genengnews.com/gen-edge/stockwatch-failed-trial-sinks-ngm-bio-will-merck-opt-into-eye-disorder-drug/', 'title': 'StockWatch: Failed Trial Sinks NGM Bio; Will Merck Opt Into Eye Disorder Drug?', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Oct 20, 2022', 'snippet': 'NGM Biopharmaceuticals (NGM) shares plunge after the company acknowledges \nthat its eye disorder candidate NGM621 failed a Phase II trial.', 'thumbnail': 'https://serpapi.com/searches/6723d1022c566d0f0ff61b5d/images/47283f7bf858131d66c4a7711ed02a763ccdbbcd663981f1ad90761c0f5207da.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7887478470802307}",,,,,,,,,,['negative'],negative,0 NCT02008227,"{'position': 1, 'link': 'https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05509-9', 'title': 'Integrating knowledge graphs into machine learning models for survival prediction and biomarker discovery in patients with non–small-cell lung cancer', 'source': 'Journal of Translational Medicine', 'date': 'Aug 5, 2024', 'snippet': 'Accurate survival prediction for Non-Small Cell Lung Cancer (NSCLC) \npatients remains a significant challenge for the scientific and clinical...', 'thumbnail': 'https://serpapi.com/searches/6723d104ee677f95bc3ebf1e/images/d32b9a274d7b0ad74208dbe606b1a2dbf76465a125fa25fbafd7743cb523cfa8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7933346629142761}","{'position': 2, 'link': 'https://www.nature.com/articles/s41698-023-00443-3', 'title': 'Deciphering transcriptomic determinants of the divergent link between PD-L1 and immunotherapy efficacy', 'source': 'Nature', 'date': 'Sep 11, 2023', 'snippet': 'Programmed cell death ligand 1 (PD-L1) expression remains the most widely \nused biomarker for predicting response to immune checkpoint...', 'thumbnail': 'https://serpapi.com/searches/6723d104ee677f95bc3ebf1e/images/d32b9a274d7b0ad71dc9ceefad5677081415b1dfb29d6b92ea5a1574126d261d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9057897925376892}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02187991,"{'position': 1, 'link': 'https://oncolo.jp/news/210518y01', 'title': 'エストロゲン受容体陽性HER2陰性/トリプルネガティブ転移性乳がん対するパクリタキセル+アリゼルチブ併用療法、パクリタキセル単剤療法に比べて無増悪生存期間を改善', 'source': 'がん情報サイト「オンコロ」', 'date': 'May 18, 2021', 'snippet': 'この記事の3つのポイント・エストロゲン受容体陽性HER2陰性/トリプルネガティブ転移性乳がん患者が対象の第2相試験・パクリタキセル+Alisertib(...', 'thumbnail': 'https://serpapi.com/searches/6723d10a577da532b1007ad1/images/372ef4755688a07a0c30b4fa5cf4adb91ee038e8e0353fe529f35938a39a9f76.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8210965991020203}",,,,,,,,,,['neutral'],neutral,1 NCT02942277,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-023-00712-z', 'title': 'A human antibody epitope map of the malaria vaccine antigen Pfs25 - npj Vaccines', 'source': 'Nature', 'date': 'Aug 4, 2023', 'snippet': 'Pfs25 is a leading antigen for a malaria transmission-blocking vaccine and \nshows moderate transmission-blocking activity and induction of rapidly \ndecreasing...', 'thumbnail': 'https://serpapi.com/searches/6723d14014c31eac29edf535/images/94c58f35a349cd72e80879f79e7b0d8003e5aed495c1812ea913f495c720cc7d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9248698353767395}","{'position': 2, 'link': 'https://www.nature.com/articles/s41541-024-00929-6', 'title': 'Antibody gene features associated with binding and functional activity in malaria vaccine-derived human mAbs', 'source': 'Nature', 'date': 'Aug 10, 2024', 'snippet': 'Here, we characterize the impact of two adjuvants, Alhydrogel® and AS01, on \nantibody clonotype diversity, binding and function, post malaria \nvaccination.', 'thumbnail': 'https://serpapi.com/searches/6723d14014c31eac29edf535/images/94c58f35a349cd72defeb4e901190edd4012c3d35183cec806b02d13db901b60.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9158818125724792}","{'position': 3, 'link': 'https://www.nature.com/articles/s42003-020-01123-9', 'title': 'Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins', 'source': 'Nature', 'date': 'Jul 24, 2020', 'snippet': 'Proteins Pfs230 and Pfs48/45 are Plasmodium falciparum \ntransmission-blocking (TB) vaccine candidates that form a membrane-bound \nprotein complex on gametes.', 'thumbnail': 'https://serpapi.com/searches/6723d14014c31eac29edf535/images/94c58f35a349cd721124b3f99b8ef4f4a5373403a7d5ee4045b0404e3dc6b388.png', 'sentiment': 'neutral', 'sentiment_prob': 0.805415689945221}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02057900,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2020.601560/full', 'title': 'Cell Therapy With Human ESC-Derived Cardiac Cells: Clinical Perspectives', 'source': 'Frontiers', 'date': 'Oct 26, 2020', 'snippet': 'In the ongoing quest for the “ideal” cell type for heart repair, \npluripotent stem cells (PSC) derived from either embryonic or \nreprogrammed...', 'thumbnail': 'https://serpapi.com/searches/6723d13e6ad3c99ad220c2ca/images/021b26e807c5f242f4c85729821ae96bfcdb123335a7cf992e2828e9df567c11.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8939337134361267}",,,,,,,,,,['neutral'],neutral,1 NCT03713593,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2020/09/04/fda-rejects-keytruda-lenvima-combo-as-first-line-treatment-for-liver-cancer/', 'title': 'FDA Rejects Keytruda-Lenvima Combo as First-line Treatment for Liver Cancer', 'source': 'Immuno-Oncology News', 'date': 'Sep 4, 2020', 'snippet': 'The U.S. Food and Drug Administration (FDA) has issued a complete response \nletter stating that it will not approve the combination of...', 'thumbnail': 'https://serpapi.com/searches/6723d1556aa36453b527f3b6/images/566d8216587f478f4fda83e4d63fc002e735446cc7de8f2a3371d34f472811e3.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6010357737541199}",,,,,,,,,,['negative'],negative,0 NCT02424799,"{'position': 1, 'link': 'https://www.nature.com/articles/s41577-023-00877-7', 'title': 'Protein kinases: drug targets for immunological disorders', 'source': 'Nature', 'date': 'May 15, 2023', 'snippet': 'Protein kinases play a major role in cellular activation processes, \nincluding signal transduction by diverse immunoreceptors.', 'thumbnail': 'https://serpapi.com/searches/6723d1f49fd30930f1a87383/images/3a085f967b65b3483866c48e918053ee38a8e3d3f4940e8c71458d055d2818cf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8678420186042786}",,,,,,,,,,['neutral'],neutral,1 NCT01469039,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/therapeutic-durability-of-aripiprazole-lauroxil/', 'title': 'Durability of Therapeutic Response With Long-Term Aripiprazole Lauroxil Treatment Following Successful Resolution of an Acute Episode of Schizophrenia', 'source': 'Psychiatrist.com', 'date': 'Sep 19, 2017', 'snippet': 'Injectable antipsychotics can help address the problem of nonadherence, \nwhich can lead to relapse. This study looks at the efficacy of the...', 'thumbnail': 'https://serpapi.com/searches/6723d1fae1d1ad99be01b6f0/images/d2646718a8c76ed2f919dac0705c93124549cf364b2c6bef500e4590b002820c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7088669538497925}",,,,,,,,,,['neutral'],neutral,1 NCT04268303,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/sublingual-dexmedetomidine-for-agitation-schizophrenia/', 'title': 'Sublingual Dexmedetomidine for the Treatment of Acute Agitation in Adults With Schizophrenia or Schizoaffective Disorder: A Randomized Placebo-Controlled Trial', 'source': 'Psychiatrist.com', 'date': 'Oct 3, 2022', 'snippet': 'This RCT determined whether a single dose of sublingual dexmedetomidine \nreduced acute agitation associated with schizophrenia or...', 'thumbnail': 'https://serpapi.com/searches/6723d189b7d31db0fc7f7d7b/images/a770f11e410eb79b2095ca25506eb2ac34be294e17bf403d4e40887f642ed046.png', 'sentiment': 'neutral', 'sentiment_prob': 0.90085369348526}",,,,,,,,,,['neutral'],neutral,1 NCT02858908,"{'position': 1, 'link': 'https://musculardystrophynews.com/news/amo-pharma-myotonic-dystrophy-therapy-improves-cognition-and-function/', 'title': 'AMO Pharma’s Myotonic Dystrophy Therapy Improves Cognition and Function, Phase 2 Trial Shows', 'source': 'Muscular Dystrophy News', 'date': 'Mar 21, 2018', 'snippet': ""AMO Pharma's myotonic dystrophy treatment improved patients' cognition, \nfatigue and ability to perform daily tasks, a Phase 2 clinical trial showed."", 'thumbnail': 'https://serpapi.com/searches/6723d1967e1d1f86725827fd/images/f550b9fac77c188c16f6a9ad23de0dc8cc257e3bd563a57dbb5d9e2cab2ca19a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7412872910499573}",,,,,,,,,,['positive'],positive,1 NCT05139810,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2402478', 'title': 'Efficacy and Safety of Donidalorsen for Hereditary Angioedema', 'source': 'The New England Journal of Medicine', 'date': 'May 31, 2024', 'snippet': 'Donidalorsen treatment reduced the hereditary angioedema attack rate, a \nfinding that supports potential prophylactic use for hereditary angioedema.', 'thumbnail': 'https://serpapi.com/searches/6723d1a198fad6961dd80bf4/images/351efbcfdc83a17afd356d9c510e6ee9565ad1cff5bb3d92bb36ba563728f391.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7784955501556396}","{'position': 2, 'link': 'https://angioedemanews.com/news/phase-3-trial-results-hae-therapy-donidalorsen-due-2024/', 'title': 'Phase 3 trial results of HAE therapy donidalorsen due in 2024 |...', 'source': 'Angioedema News', 'date': 'Jun 5, 2023', 'snippet': 'Results from the placebo-controlled study, dubbed OASIS-HAE (NCT05139810), \nare expected in the first half of 2024.', 'thumbnail': 'https://serpapi.com/searches/6723d1a198fad6961dd80bf4/images/351efbcfdc83a17a882627374d4eb550dc0ddc8f41bea1c75c3f6077491d92e9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9253244996070862}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02670538,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0165032724010309', 'title': 'Early improvement with cariprazine as a predictor of antidepressant, anxiolytic, and antimanic response in bipolar I mania and depression: A pooled post hoc analysis of randomized cariprazine trials', 'source': 'ScienceDirect.com', 'date': 'Jun 27, 2024', 'snippet': 'Early symptomatic improvement may predict treatment response in bipolar I \ndisorder. Cariprazine has demonstrated early treatment effects in bipolar \nI...', 'thumbnail': 'https://serpapi.com/searches/6723d1bb922ccec6df09d394/images/9799ce315a80aee38972fbec74ec82ff473538dd84ae1d8f900b5327eaf03787.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7281509637832642}",,,,,,,,,,['neutral'],neutral,1 NCT01965353,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-021-00407-5', 'title': 'Phase 1 open-label study of panobinostat, lenalidomide, bortezomib + dexamethasone in relapsed and relapsed/refractory multiple myeloma', 'source': 'Nature', 'date': 'Feb 5, 2021', 'snippet': 'Panobinostat is among the most potent HDACis in clinical development and \nthe only HDACi approved for the treatment of RRMM, in combination with \nbortezomib and...', 'thumbnail': 'https://serpapi.com/searches/6723d1c314c31eac29edf553/images/81687c2f5db2f53c07d3e98cb202e994a2909e50fd31494465ef81a36e6ab9db.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6467630863189697}",,,,,,,,,,['neutral'],neutral,1 NCT04245709,"{'position': 1, 'link': 'https://alsnewstoday.com/news/asthma-medicine-slows-als-disease-progression-small-trial/', 'title': 'Asthma medicine slows ALS disease progression in small trial', 'source': 'ALS News Today', 'date': 'Jul 25, 2023', 'snippet': 'Among the 11 ALS patients who completed the 24-week study, clenbuterol was \nassociated with lung function gains and increased strength.', 'thumbnail': 'https://serpapi.com/searches/6723d1df9872176ea7feee56/images/34b78a03ff6d8d05933039072ce7e9d39fccfa9045d2df2d5f1dc1e8b6d80697.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8271586298942566}",,,,,,,,,,['neutral'],neutral,1 NCT04045405,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-020-14349-2', 'title': 'Preclinical development of a miR-132 inhibitor for heart failure treatment', 'source': 'Nature', 'date': 'Jan 31, 2020', 'snippet': 'We propose that miR-132 may serve as a therapeutic target in HF therapy. \nHere we report mode of action details of a locked nucleic acid based \nantisense...', 'thumbnail': 'https://serpapi.com/searches/6723d1f00f1a336e4473aa4d/images/218c5b73e9c5fc2147cd2ea2933cc21f13f61e03606abaa166f7a020ead78728.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7852481603622437}",,,,,,,,,,['neutral'],neutral,1 NCT02315703,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/experimental-hiv-vaccine-regimen-well-tolerated-elicits-immune-responses', 'title': 'Experimental HIV vaccine regimen is well-tolerated, elicits immune responses', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jul 24, 2017', 'snippet': 'Results from an early-stage clinical trial called APPROACH show that an \ninvestigational HIV vaccine regimen was well-tolerated and generated immune \nresponses...', 'thumbnail': 'https://serpapi.com/searches/6723d22a749783a716793b21/images/be339a895b4c93f81532064e2927f376a25a858858dddc551641e11a86998a5a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5365678668022156}",,,,,,,,,,['positive'],positive,1 NCT01968187,"{'position': 1, 'link': 'https://praderwillinews.com/news/fda-wants-additional-trial-pws-nasal-spray-lv-101-confirm-efficacy/', 'title': 'FDA Wants Additional Trial of PWS Nasal Spray LV-101 to Confirm Efficacy', 'source': 'Prader-Willi Syndrome News', 'date': 'Jan 20, 2022', 'snippet': 'The US Food and Drug Administration (FDA) has told Levo Therapeutics that \nan additional clinical trial will be necessary to confirm the efficacy of \nLV-101.', 'thumbnail': 'https://serpapi.com/searches/6723d239f59d009e292086df/images/bfb4178a4f29758df4879c02a3db26e06294b10a7582731291c5aaecbb6b19b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8743943572044373}","{'position': 2, 'link': 'https://praderwillinews.com/news/acadia-trial-testing-carbetocin-nasal-spray-hyperphagia-pws/', 'title': 'New Acadia trial testing carbetocin nasal spray to treat insatiable hunger in PWS', 'source': 'Prader-Willi Syndrome News', 'date': 'Dec 7, 2023', 'snippet': 'Acadia Pharmaceuticals has launched a Phase 3 clinical trial testing the \nsafety and efficacy of ACP-101, an experimental carbetocin nasal spray, for \nthe...', 'thumbnail': 'https://serpapi.com/searches/6723d239f59d009e292086df/images/bfb4178a4f29758d834480d64d2e4d0bd16e01d656d1717484285739f1df97fa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8832798004150391}","{'position': 3, 'link': 'https://praderwillinews.com/news/phase-2-trial-shows-lv-101-reduces-symptoms-pws-children/', 'title': 'Potential PWS Therapy LV-101 Reduces Symptoms in Children, Trial Finds', 'source': 'Prader-Willi Syndrome News', 'date': 'Jun 25, 2018', 'snippet': ""Results from a Phase 2 clinical trial show that Levo Therapeutics' lead \ntherapy candidate, LV-101 (intranasal carbetocin), can effectively reduce \nsymptoms of..."", 'thumbnail': 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NCT03332212,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223014841', 'title': 'Empagliflozin treatment of cardiotoxicity: A comprehensive review of clinical, immunobiological, neuroimmune, and therapeutic implications', 'source': 'ScienceDirect.com', 'date': 'Oct 19, 2023', 'snippet': 'In this review, we discuss the protective effects of EMPA in \nchemotherapy-induced cardiotoxicity from molecular, immunological, and \nneuroimmunological aspects.', 'thumbnail': 'https://serpapi.com/searches/6723d2614a3fcfdcc671a152/images/a4bf1024cfac29d0fadb911e30b070cb2a492c59e9d9d93e23f79b23017f842e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8832970261573792}",,,,,,,,,,['neutral'],neutral,1 NCT04707313,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/pfizers-weight-loss-drug-hits-primary-endpoint-in-phase-iib-trial/', 'title': 'Pfizer’s weight loss drug hits primary endpoint in Phase IIb trial', 'source': 'Clinical Trials Arena', 'date': 'Dec 1, 2023', 'snippet': ""Pfizer's entry into the obesity drug market has seen successful progression \nas it joins the multi-billion dollar weight loss market."", 'thumbnail': 'https://serpapi.com/searches/6723d2612e33c808cd2ff169/images/8ff30a0769759761204892e3068ce829553ac1c3028777b00ad99cf10f01a471.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8142448663711548}","{'position': 2, 'link': 'https://www.biopharmadive.com/news/biotech-10-clinical-trials-watch-2023-second-half/653845/', 'title': '10 clinical trials to watch in the second half of 2023', 'source': 'BioPharma Dive', 'date': 'Jun 28, 2023', 'snippet': 'A Duchenne gene therapy faces a crucial test, while highly anticipated \nstudy results lay ahead in lung cancer, obesity and heart disease.', 'thumbnail': 'https://serpapi.com/searches/6723d2612e33c808cd2ff169/images/8ff30a07697597611916f65bd8a00be2de4a348f2c77aa84217df61699e2b1a1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.790732741355896}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02054897,"{'position': 1, 'link': 'https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trial-snapshot-ozempic', 'title': 'Drug Trial Snapshot: Ozempic', 'source': 'U.S. Food and Drug Administration (.gov)', 'date': 'Aug 20, 2020', 'snippet': 'HOW TO USE THIS SNAPSHOT The information provided in Snapshots highlights \nwho participated in the clinical trials that supported the FDA...', 'thumbnail': 'https://serpapi.com/searches/6723d299f9338828b180e1f1/images/ab2b889246677da18d276b48d113423638151e4f62b6c671824c74076cffdcd5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9079004526138306}","{'position': 2, 'link': 'https://www.medwirenews.com/showcase/a-quick-guide-to-the-sustain-trials/', 'title': 'A quick guide to the SUSTAIN trials', 'source': 'medwirenews.com', 'date': 'Apr 7, 2017', 'snippet': 'Here is our guide to the 15 trials launched to date, which are complete, \nand which have so far been published in a peer-reviewed journal.', 'thumbnail': 'https://serpapi.com/searches/6723d299f9338828b180e1f1/images/ab2b889246677da10aec7d1bb770e9166a5830f2f5869fc53e5cca4dfa918746.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.865156352519989}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03954834,"{'position': 1, 'link': 'https://www.renalandurologynews.com/news/tirzepatide-vs-semaglutide-lower-metabolic-syndrome-prevalence/', 'title': 'Tirzepatide vs Semaglutide Linked to Lower Metabolic Syndrome Prevalence', 'source': 'Renal and Urology News', 'date': 'Apr 12, 2024', 'snippet': 'Use of tirzepatide, compared with placebo, semaglutide, and insulin \ndegludec and glargine, is associated with a lower prevalence of metabolic \nsyndrome among...', 'thumbnail': 'https://serpapi.com/searches/6723d2a50f1a336e4473aa72/images/33981df3de5e18d71de977b3a74ebb1d7a37663c4ae13e54608daa74de28db0a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8086218237876892}","{'position': 2, 'link': 'https://investor.lilly.com/news-releases/news-release-details/lillys-surpass-1-results-published-lancet-show-tirzepatides', 'title': ""Lilly's SURPASS-1 results published in The Lancet show tirzepatide's superior A1C and body weight reductions versus placebo in adults with type 2 diabetes"", 'source': 'Eli Lilly and Company', 'date': 'Jun 26, 2021', 'snippet': ""Data presented at ADA's 81st Scientific Sessions® show the highest dose of \ntirzepatide (15 mg) reduced A1C by 2.07 percent and weight by 9.5 kg (20.9 \nlb., 11.0..."", 'thumbnail': 'https://serpapi.com/searches/6723d2a50f1a336e4473aa72/images/33981df3de5e18d7743afe728373eceab6ee230cab62fffd4bf27adeb9bd4b4b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5547938942909241}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04759768,"{'position': 1, 'link': 'https://www.empr.com/home/news/opvee-nasal-spray-approved-for-treatment-of-opioid-overdose/', 'title': 'Opvee Nasal Spray Approved for Treatment of Opioid Overdose', 'source': 'Medical Professionals Reference', 'date': 'May 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Opvee (nalmefene) nasal \nspray for the emergency treatment of known or suspected overdose induced by \nnatural...', 'thumbnail': 'https://serpapi.com/searches/6723d2a97a12fd36d112a05f/images/74536ea478aaddb7fd87f258d33e0a09ea6ce391729e0286307bef1012729d32.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8920722007751465}",,,,,,,,,,['neutral'],neutral,1 NCT03058289,"{'position': 1, 'link': 'https://www.onclive.com/view/int230-6-alone-with-ipilimumab-induces-positive-os-results-in-metastatic-sarcomas', 'title': 'INT230-6 Alone, With Ipilimumab Induces Positive OS Results in Metastatic Sarcomas', 'source': 'OncLive', 'date': 'Dec 30, 2022', 'snippet': 'INT230-6 demonstrated direct tumor killing in soft tissue sarcoma and \nelicits an anti-cancer immune response within the injected tumor both...', 'thumbnail': 'https://serpapi.com/searches/6723d2b729e6fb4ffa08bfb9/images/7ed99248b557312cd0f69f1230d9e87e13136f5415057b4da09d2ea28f70f2a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8363605737686157}",,,,,,,,,,['neutral'],neutral,1 NCT01877668,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1615975', 'title': 'Tofacitinib or Adalimumab versus Placebo for Psoriatic Arthritis', 'source': 'The New England Journal of Medicine', 'date': 'Oct 19, 2017', 'snippet': 'Tofacitinib is an oral Janus kinase inhibitor that is under investigation \nfor the treatment of psoriatic arthritis. We evaluated tofacitinib...', 'thumbnail': 'https://serpapi.com/searches/6723d2c2bcd652fc3b3dc3ac/images/8082cef55897aedb870f11929684c659dff770dfbe925207c0ce51e0b34dc17f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9073402285575867}","{'position': 2, 'link': 'https://psoriasisnewstoday.com/2016/12/08/pfizer-phase-3-opal-trials-show-xeljanz-benefits-psoriatic-arthritis-patients/', 'title': 'Phase 3 Trials of Xeljanz in Psoriatic Arthritis Show Benefit', 'source': 'Psoriasis News Today', 'date': 'Dec 8, 2016', 'snippet': 'Pfizer presented positive results from its Phase 3 OPAL clinical program \nevaluating the effectiveness and safety of Xeljanz (tofacitinib...', 'thumbnail': 'https://serpapi.com/searches/6723d2c2bcd652fc3b3dc3ac/images/8082cef55897aedb8647e67349e80bb2fc2bc8cdf68711c927c1edfdb8d1ba07.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6341595649719238}","{'position': 3, 'link': 'https://psoriasisnewstoday.com/2017/05/04/psoriatic-arthritis-therapy-xeljanz-reviewed-fda-following-approval-pfizer-snda/', 'title': 'FDA Accepts Pfizer’s Supplemental New Drug Application for Xeljanz to Treat Active Psoriatic Arthritis Patients', 'source': 'Psoriasis News Today', 'date': 'May 4, 2017', 'snippet': ""The U.S. Food and Drug Administration (FDA) will review Pfizer's medication \nXeljanz (tofacitinib citrate) 5 mg twice daily, to treat adults..."", 'thumbnail': 'https://serpapi.com/searches/6723d2c2bcd652fc3b3dc3ac/images/8082cef55897aedb98953d312596045a74d368858905a3082ffa3ff3b40f3aba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9127993583679199}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT04582201,"{'position': 1, 'link': 'https://www.oncozine.com/first-pateint-dosed-with-allogeneic-off-the-shelf-invariant-natural-killer-t-cell-therapy/', 'title': 'First Pateint Dosed with Allogeneic, off-the-shelf, Invariant Natural Killer T-cell Therapy', 'source': ""Onco'Zine"", 'date': 'Mar 3, 2022', 'snippet': 'A first patient has been dosed with a novel, allogeneic, off-the-shelf, \ninvariant natural killer T (iNKT) cell therapy to treat cancer and other \nimmune-...', 'thumbnail': 'https://serpapi.com/searches/6723d3062c566d0ec8034c98/images/d5be052205c76c4fd15a9dfb02ebcd5be6ef109c3c1cfbecd122c20fb065db8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8653754591941833}",,,,,,,,,,['neutral'],neutral,1 NCT02993406,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2215024', 'title': 'Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients', 'source': 'The New England Journal of Medicine', 'date': 'Mar 4, 2023', 'snippet': 'Bempedoic acid, an ATP citrate lyase inhibitor, reduces low-density \nlipoprotein (LDL) cholesterol levels and is associated with a low...', 'thumbnail': 'https://serpapi.com/searches/6723d3103d629b1615675019/images/8cfecd6c042329d821aaf5724894596f1e21f6967584a37c2d108fd748d704c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8117720484733582}","{'position': 2, 'link': 'https://www.managedhealthcareexecutive.com/view/key-data-analysis-from-clear-outcomes-trial', 'title': 'Key Data Analysis from CLEAR Outcomes Trial', 'source': 'Managed Healthcare Executive', 'date': 'Jun 7, 2023', 'snippet': 'Leslie Cho, M.D., FACC, FESC, FSCAI: Maybe we can now jump toward the \noutcome of the trial [CLEAR Outcomes, NCT02993406].', 'thumbnail': 'https://serpapi.com/searches/6723d3103d629b1615675019/images/8cfecd6c042329d855cf15a85424e0b2593978ea4a5f501107c72dba2263261a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7394821643829346}","{'position': 3, 'link': 'https://www.drugtopics.com/view/fda-approves-updated-ldl-c-lowering-indication-for-esperion-s-nexletol-nexlizet-tablets', 'title': 'FDA Approves Updated LDL-C Lowering Indication for Esperion’s Nexletol, Nexlizet Tablets', 'source': 'Drug Topics', 'date': 'Dec 18, 2023', 'snippet': 'The federal agency also removed the maximally tolerated qualifier for \nstatin use and the prior cardiovascular morbidity and mortality...', 'thumbnail': 'https://serpapi.com/searches/6723d3103d629b1615675019/images/8cfecd6c042329d8cec590f2200a91042ac9cd78885f68d72736e5d33779239a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7774533629417419}","{'position': 4, 'link': 'https://www.empr.com/home/news/fda-approval-broadens-eligibility-for-treatment-with-nexletol-nexlizet/', 'title': 'FDA Approval Broadens Eligibility for Treatment With Nexletol, Nexlizet', 'source': 'Medical Professionals Reference', 'date': 'Mar 25, 2024', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of Nexletol\n® (bempedoic acid 180mg tablets) and Nexlizet® (bempedoic acid...', 'thumbnail': 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'title': 'A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH', 'source': 'The New England Journal of Medicine', 'date': 'Oct 20, 2021', 'snippet': 'Management of nonalcoholic steatohepatitis (NASH) is an unmet clinical \nneed. 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2020', 'snippet': 'The Food and Drug Administration (FDA) has granted Fast Track designation \nto delgocitinib cream (Leo Pharma) for the treatment of adults with \nmoderate to...', 'thumbnail': 'https://serpapi.com/searches/6723d36730dfc1525c009246/images/e73dc6bc1995cda6c7de07f4eb58f9b21e4f4d7a1fcec576f3eff9ef9b59cecc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.786065936088562}",,,,,,,,,,['neutral'],neutral,1 NCT02269423,"{'position': 1, 'link': 'https://www.nature.com/articles/srep27944', 'title': 'Circulating follicular T helper cells and cytokine profile in humans following vaccination with the rVSV-ZEBOV Ebola vaccine | Scientific Reports', 'source': 'Nature', 'date': 'Jun 21, 2016', 'snippet': 'We analyzed human cellular immune responses induced by a single dose of the \nrVSV-ZEBOV vaccine candidate, which showed significant protective efficacy \nin...', 'thumbnail': 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in advanced renal cell carcinoma', 'source': 'Nature', 'date': 'Mar 26, 2018', 'snippet': 'In the phase 3 METEOR trial (NCT01865747), cabozantinib significantly \nimproved progression-free survival, overall survival, and objective...', 'thumbnail': 'https://serpapi.com/searches/6723d37b3c863d7b6c1233a2/images/4a899f632badef3b99e060f73fdd3680c613535e9cdded6e151f22d7f3a05f7c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7984726428985596}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/post-immunotherapy-cabozantinib-safe-feasible-for-metastatic-rcc-after-treatment-failure', 'title': 'Post-Immunotherapy Cabozantinib Safe, Feasible for Metastatic RCC After Treatment Failure', 'source': 'Cancer Network', 'date': 'Feb 19, 2022', 'snippet': 'New findings indicate that treatment with cabozantinib following failure of \nimmunotherapy proved to be safe and feasible in metastatic renal cell \ncarcinoma.', 'thumbnail': 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mirvetuximab soravtansine to have \nencouraging efficacy and a tolerable safety profile in patients with...', 'thumbnail': 'https://serpapi.com/searches/6723d440efad215bb81d42a9/images/792a3b1d44b0ebd212837f9cb70184671831494bfcc5c64282163124f6db9439.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.662169873714447}","{'position': 2, 'link': 'https://www.immunogen.com/patients-and-caregivers/', 'title': 'Patients and Caregivers |ImmunoGen ADC Technology-focused Cancer Treatments', 'source': 'ImmunoGen', 'date': 'May 14, 2018', 'snippet': 'Patients and caregivers are often blind-sided by cancer diagnoses and \nconfused by our complicated treatment plan using ADC Technology. Learn more \nhere.', 'thumbnail': 'https://serpapi.com/searches/6723d440efad215bb81d42a9/images/792a3b1d44b0ebd2309ac1132c727ddcc0e8175acee2a75490e612acfcdebde4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5577406287193298}","{'position': 3, 'link': 'https://www.cancerhealth.com/article/fda-approves-new-treatment-option-ovarian-cancer', 'title': 'FDA Approves New Treatment Option for Ovarian Cancer', 'source': 'Cancer Health', 'date': 'Nov 17, 2022', 'snippet': 'Elahere, a new antibody-drug conjugate, shrank tumors in about a third of \ntreatment-experienced patients.', 'thumbnail': 'https://serpapi.com/searches/6723d440efad215bb81d42a9/images/792a3b1d44b0ebd209c6dd6c4336e3d37a4731e3f1c7941d7a89f5034b48ca3e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7404248118400574}","{'position': 4, 'link': 'https://www.empr.com/home/news/elahere-granted-accelerated-approval-for-platinum-resistant-ovarian-cancer/', 'title': 'Elahere Granted Accelerated Approval for Platinum-Resistant Ovarian Cancer - MPR', 'source': 'Medical Professionals Reference', 'date': 'Nov 15, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted accelerated approval to \nElahere (mirvetuximab soravtansine-gynx) for the treatment of adult \npatients with...', 'thumbnail': 'https://serpapi.com/searches/6723d440efad215bb81d42a9/images/792a3b1d44b0ebd28d1fad53d67607e17fafe80e8df0295a672014bf5e3a9fd7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8012616038322449}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00259376,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa054686', 'title': 'Dronedarone for Maintenance of Sinus Rhythm in Atrial Fibrillation or Flutter', 'source': 'The New England Journal of Medicine', 'date': 'Sep 6, 2007', 'snippet': 'In two identical multicenter, double-blind, randomized trials, one \nconducted in Europe (ClinicalTrials.gov number, NCT00259428) and one...', 'thumbnail': 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Heart Failure and Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Apr 7, 2024', 'snippet': 'Obesity and type 2 diabetes are prevalent in patients with heart failure \nwith preserved ejection fraction and are characterized by a high symptom \nburden.', 'thumbnail': 'https://serpapi.com/searches/6723d48ed0c98349f3f117ce/images/5fd2add37440235eed76db90bd0402f1ae793a0ba455130ddb42c4d23b57ae56.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6510336995124817}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT04141670,"{'position': 1, 'link': 'https://www.bioworld.com/articles/675357-arm-210-studied-in-new-clinical-trial-for-ryanodine-receptor-type-1-related-myopathies', 'title': 'ARM-210 studied in new clinical trial for ryanodine receptor type 1-related myopathies', 'source': 'BioWorld MedTech', 'date': 'Dec 18, 2019', 'snippet': 'ARMGO Pharma has announced the initiation of a clinical trial of ARM-210 \n(S-48168) for the treatment for patients with ryanodine receptor...', 'thumbnail': 'https://serpapi.com/searches/6723d489f60b6f6962215197/images/f52d9f103f610ad9c7cbf9dee20d63dc177a439ac0e5e62a7e566838743f3f0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8976263999938965}",,,,,,,,,,['neutral'],neutral,1 NCT02105948,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1708208', 'title': 'Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease', 'source': 'The New England Journal of Medicine', 'date': 'Sep 12, 2017', 'snippet': 'We performed two phase 3, randomized, placebo-controlled, double-blind, \nparallel-group trials comparing mepolizumab (100 mg in METREX,...', 'thumbnail': 'https://serpapi.com/searches/6723d49ca2e99c954cff3b19/images/74ccc71da01a9b5490c7a73938aceeb3a7870759884f9224a353f3f2cad3f055.png', 'sentiment': 'neutral', 'sentiment_prob': 0.860298752784729}","{'position': 2, 'link': 'https://copdnewstoday.com/news/mepolizumab-antibody-copd-lessens-exacerbations-improves-quality-of-life/', 'title': 'Mepolizumab Lessens Exacerbations, Improves Quality of Life', 'source': 'COPD News Today', 'date': 'Aug 9, 2021', 'snippet': 'mepolizumab, an antibody designed to lower the levels of eosinophils — \nimmune cells linked with worse chronic obstructive pulmonary disease (...', 'thumbnail': 'https://serpapi.com/searches/6723d49ca2e99c954cff3b19/images/74ccc71da01a9b54e131fbfb667a5c61336e71d903df66c58b16ddc7779b8e6d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6641448736190796}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03654274,"{'position': 1, 'link': 'https://www.empr.com/home/news/myfembree-approved-for-management-of-endometriosis-pain/', 'title': 'Myfembree Approved for Management of Endometriosis Pain', 'source': 'Medical Professionals Reference', 'date': 'Aug 8, 2022', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of \nMyfembree® (relugolix, estradiol, and norethindrone acetate) to include...', 'thumbnail': 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Aeruginosa Infection in NCFBE Patients', 'source': 'Bronchiectasis News Today', 'date': 'Jul 28, 2017', 'snippet': 'Aradigm has submitted a new drug application (NDA) to the US Food and Drug \nAdministration (FDA) for Linhaliq (ciprofloxacin) as a treatment for \nnon-cystic...', 'thumbnail': 'https://serpapi.com/searches/6723d50c48c429c80104c466/images/d11681bda91ea643e80d2b619a051ac35a660e875a560e329d8dc2c03acbf6f0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921363890171051}","{'position': 3, 'link': 'https://bronchiectasisnewstoday.com/2017/09/26/fda-accepts-aradigms-nda-for-linhaliq-to-treat-non-cystic-fibrosis-bronchiectasis/', 'title': ""Aradigm's NDA for Linhaliq for non-CF Bronchiectasis Accepted by FDA"", 'source': 'Bronchiectasis News Today', 'date': 'Sep 26, 2017', 'snippet': 'A new drug application (NDA) submitted by Aradigm for Linhaliq (inhaled \nciprofloxacin) was recently accepted for filing with priority review...', 'thumbnail': 'https://serpapi.com/searches/6723d50c48c429c80104c466/images/d11681bda91ea64313c6bb19d64b6434584dc1676c70ffb8e8fb5576484a4775.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7861056923866272}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03150862,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-021-01632-2', 'title': 'Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours', 'source': 'Nature', 'date': 'Nov 18, 2021', 'snippet': 'Pamiparib, a PARP1/2 inhibitor, demonstrated antitumor activity in \npreclinical models. This Phase 1A/1B dose-escalation/dose-expansion study...', 'thumbnail': 'https://serpapi.com/searches/6723d5115235f6e4905ed5ac/images/d7931de8c5b7549ce17e06d56f3218f767950d7ab0d5923ac15089f2d7cca262.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8837805390357971}",,,,,,,,,,['neutral'],neutral,1 NCT05297578,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/pneumococcal-24-valent-conjugate-vaccine-gets-fast-track-designation/', 'title': 'Pneumococcal 24-Valent Conjugate Vaccine Gets Fast Track Designation', 'source': 'Medical Professionals Reference', 'date': 'Aug 4, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted Fast Track designation \nto VAX-24 for the prevention of invasive pneumococcal disease in adults 18 \nyears of...', 'thumbnail': 'https://serpapi.com/searches/6723d517b6e4dbfe4c292d08/images/ce456507ce012e9284a5df35d2881579362d632e95baf0092adfea5a3f0ce653.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Oncology Therapeutics', 'source': 'Clinical Leader', 'date': 'Apr 21, 2023', 'snippet': 'On April 6, 2023, AbbVie announced that it was voluntarily withdrawing \nibrutinib, which was granted accelerated approval for two...', 'thumbnail': 'https://serpapi.com/searches/6723d53bcdf1558f138a344b/images/63f2c7d3fe747eb69a23e1cd4053a585b75fc5f054965da42d3b89cd4e05cef5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8708025217056274}","{'position': 2, 'link': 'https://www.oncnursingnews.com/view/ibrutinib-is-no-longer-available-for-mantle-cell-lymphoma-or-marginal-zone-lymphoma-in-the-united-states', 'title': 'Ibrutinib is No Longer Available for Mantle Cell Lymphoma or Marginal Zone Lymphoma in the United States', 'source': 'Oncology Nursing News', 'date': 'Apr 14, 2023', 'snippet': 'AbbVie has withdrawn the indications for previously pretreated patients \nwith mantle cell lymphoma and marginal zone lymphoma.', 'thumbnail': 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evaluate the \nsafety and effectiveness of its experimental anti-inflammatory therapy \nZYIL1 in people...', 'thumbnail': 'https://serpapi.com/searches/6723d741861b9d38e4f1e6fc/images/9293230fcde1ef67def5b3a056f3c142d675594624b8a38d5a04641774c8b6c9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8816696405410767}","{'position': 2, 'link': 'https://health.economictimes.indiatimes.com/news/pharma/pharma-industry/zydus-begins-phase-ii-trial-of-zyil1-nlrp3-inhibitor-in-patients-with-als/104689856', 'title': 'Zydus begins Phase II trial of ZYIL1, NLRP3 inhibitor in patients with ALS', 'source': 'ET HealthWorld', 'date': 'Oct 25, 2023', 'snippet': ""Zydus Life Sciences is to initiate the Phase II clinical study of NLRP3 \ninhibitor 'ZYIL1' in patients with amyotrophic lateral sclerosis (ALS)."", 'thumbnail': 'https://serpapi.com/searches/6723d741861b9d38e4f1e6fc/images/9293230fcde1ef67510d66e6574492f648e9d62aeef3d4f8e4a4975f02505e1e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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""The data from two Phase III trials demonstrated GLP-1/glucagon agonist's \nefficacy in reducing blood glucose and weight."", 'thumbnail': 'https://serpapi.com/searches/6723d75139e23253ca9df388/images/fae2385cfec4ee7059d645c9a3b7466ef1035050467084b7be8a945d28317f87.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7004231810569763}","{'position': 2, 'link': 'https://www.manilatimes.net/2024/09/12/tmt-newswire/pr-newswire/head-to-head-superiority-over-dulaglutide-innovents-phase-3-clinical-trial-dreams-2-of-mazdutide-in-chinese-patients-with-type-2-diabetes-were-orally-presented-at-easd-2024/1970914', 'title': ""Head-to-head Superiority over Dulaglutide: Innovent's Phase 3 Clinical Trial DREAMS-2 of Mazdutide in Chinese Patients with Type 2 Diabetes were Orally Presented at EASD 2024"", 'source': 'The Manila Times', 'date': '1 month ago', 'snippet': 'SAN FRANCISCO and SUZHOU, China, Sept. 12, 2024 /PRNewswire/ -- Innovent \nBiologics, Inc. (Innovent) (HKEX: 01801), a world-class...', 'thumbnail': 'https://serpapi.com/searches/6723d75139e23253ca9df388/images/fae2385cfec4ee70d6e942ecb5f4c13bc13f3c6d25f1830f714b9539f66ed8f1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7202430963516235}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02770378,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-024-02608-8', 'title': 'Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro', 'source': 'Nature', 'date': 'Feb 23, 2024', 'snippet': 'Glioblastoma represents a brain tumor with a notoriously poor prognosis. \nFirst-line therapy may include adjunctive Tumor Treating Fields...', 'thumbnail': 'https://serpapi.com/searches/6723d756fc183d321a411178/images/c37f870e663f334374ac1d9d350b830752071a5d57c53feea5ebca97f0271d58.jpeg', 'sentiment': 'negative', 'sentiment_prob': 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cysteine-dependent \nproteases that are involved in many vital cellular processes including...', 'thumbnail': 'https://serpapi.com/searches/6723d5712b5fa75457cfec6c/images/9d94480568179dac0f29c5be783d75ee35b8ee7da3914fd2092af5eab55a0481.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8237717151641846}",,,,,,,,,,['neutral'],neutral,1 NCT04001803,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1909512', 'title': 'Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection', 'source': 'The New England Journal of Medicine', 'date': 'Mar 4, 2020', 'snippet': 'Long-acting injectable regimens may simplify therapy for patients with \nhuman immunodeficiency virus type 1 (HIV-1) infection.We conducted a phase \n3,...', 'thumbnail': 'https://serpapi.com/searches/6723d57b2a7727c51fde5564/images/82e94ca81ce0cab70238da7e32bc2b4de032239b3bd9465400451350eb5790d3.png', 'sentiment': 'neutral', 'sentiment_prob': 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'Aug 8, 2022', 'snippet': ""The U.S. Food and Drug Administration has affirmed its decision rejecting \nNuplazid as a treatment for Alzheimer's disease-related psychosis."", 'thumbnail': 'https://serpapi.com/searches/6723d6fe30dfc1525c009357/images/8e02d1ff37d05cf6032d542ede0bfed3fac2da900adbdf27b115f91f7f33152b.png', 'sentiment': 'negative', 'sentiment_prob': 0.6054498553276062}",,,,,,,,,,['negative'],negative,0 NCT03267316,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/fda-grants-orphan-drug-designation-to-nt-i7-in-advanced-pancreatic-cancer', 'title': 'FDA Grants Orphan Drug Designation to NT-I7 in Advanced Pancreatic Cancer', 'source': 'Cancer Network', 'date': 'Feb 5, 2024', 'snippet': 'Treatment with NT-I7 may boost the immune system and enhance antitumor \nactivity in patients with pancreatic cancer and other solid tumors.', 'thumbnail': 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'https://www.cancernetwork.com/view/atezolizumab-plus-bevacizumab-induces-promising-clinical-responses-in-neuroendocrine-tumors', 'title': 'Atezolizumab Plus Bevacizumab Induces Promising Clinical Responses in Neuroendocrine Tumors', 'source': 'Cancer Network', 'date': 'Jul 19, 2022', 'snippet': 'The use of atezolizumab (Tecentriq) and bevacizumab (Avastin) yielded \npromising clinical responses and progression-free survival (PFS) in...', 'thumbnail': 'https://serpapi.com/searches/6723d6d9e10f0aab3a6244d9/images/22a1972b0aea68f35df365f995f311ab7c0c25fc56f43653c75a22a8417c2dc9.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5143183469772339}","{'position': 4, 'link': 'https://www.cancernetwork.com/view/eileen-m-oreilly-md-challenges-treating-patients-pancreatic-cancer', 'title': 'Eileen M. O’Reilly, MD, on the Challenges of Treating Patients with Pancreatic Cancer', 'source': 'Cancer Network', 'date': 'Jan 27, 2020', 'snippet': 'The medical oncologist from Memorial Sloan Kettering Cancer Center \ndiscussed challenges in treating patients with pancreatic center,...', 'thumbnail': 'https://serpapi.com/searches/6723d6d9e10f0aab3a6244d9/images/22a1972b0aea68f38900f73a3fb0d1341d9f0030d40382b2740b17c48751ce1b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9265167713165283}","{'position': 5, 'link': 'https://www.cancernetwork.com/view/frontline-nalirifox-approved-by-fda-in-metastatic-pdac', 'title': 'Frontline NALIRIFOX Approved by FDA in Metastatic PDAC', 'source': 'Cancer Network', 'date': 'Feb 13, 2024', 'snippet': 'Patients with metastatic pancreatic ductal adenocarcinoma may now receive \nirinotecan liposome in combination with 5-fluorouracil/leucovorin...', 'thumbnail': 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nadunolimab in treatment of pancreatic c', 'source': 'Notimérica', 'date': 'May 26, 2022', 'snippet': '(NASDAQ Stockholm: CANTA) today reported extended interim results in \nfirst-line pancreatic cancer (PDAC)...', 'thumbnail': 'https://serpapi.com/searches/6723d6d9e10f0aab3a6244d9/images/22a1972b0aea68f3898509639828c2db8b1cde81ad971ac29e4bd7f60bc95729.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7977784276008606}",,,"['positive', 'neutral', 'positive', 'neutral', 'neutral', 'neutral', 'neutral', 'positive']",neutral,1 NCT04039113,"{'position': 1, 'link': 'https://copdnewstoday.com/news/adults-with-moderate-severe-copd-saw-fewer-exacerabations-with-tezepelumab/', 'title': 'Adults with moderate, severe COPD saw fewer exacerbations with tezepelumab', 'source': 'COPD News Today', 'date': 'May 20, 2024', 'snippet': 'Tezepelumab, which is approved for severe asthma, tended to reduce the \nfrequency of exacerbations in adults with moderate to very severe chronic \nobstructive...', 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It is mainly used in familial...', 'thumbnail': 'https://serpapi.com/searches/6723d6707c1712ec9a29f3ee/images/9cd397c5696edb5a460876184479063523e76e2f36b1452d2017b174918ea5f3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8262351751327515}",,,,,,,,,,['neutral'],neutral,1 NCT02948569,"{'position': 1, 'link': 'https://liverdiseasenews.com/news/denifanstat-safely-treat-nash-phase-2b-clinical-trial/', 'title': 'Denifanstat seen to safely treat NASH in Phase 2b clinical trial', 'source': 'Liver Disease News', 'date': 'Feb 5, 2024', 'snippet': 'Denifanstat outperformed a placebo at resolving nonalcoholic \nsteatohepatitis in patients with moderate to severe liver fibrosis \ntreated...', 'thumbnail': 'https://serpapi.com/searches/6723d684b57db8ce1fd87bd0/images/38b2eebc4ac1336efbd29004633023957427054e242d88da3d2d5ee56ef92b16.png', 'sentiment': 'positive', 'sentiment_prob': 0.5272930264472961}",,,,,,,,,,['positive'],positive,1 NCT04674189,"{'position': 1, 'link': 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now-discontinued experimental treatment for Sanfilippo syndrome \ntype A, was generally well-tolerated in a clinical trial.', 'thumbnail': 'https://serpapi.com/searches/6723d772910986a69be96212/images/ba3fc45cee08ddb7d0802106a1235d7a23b8f467f04bd2429117cb0ea94aac7a.png', 'sentiment': 'positive', 'sentiment_prob': 0.7193895578384399}",,,,,,,,,,['positive'],positive,1 NCT02941328,"{'position': 1, 'link': 'https://smanewstoday.com/news/top-10-sma-stories-2023/', 'title': 'Top 10 SMA stories of 2023', 'source': 'SMA News Today', 'date': 'Jan 3, 2024', 'snippet': 'Here are the Top 10 spinal muscular atrophy news stories brought to our SMA \nNews Today readers in 2023.', 'thumbnail': 'https://serpapi.com/searches/6723d78bce1e107b7720327e/images/1262457feea2a7efaa82445e9cb4d5dfc766c478d0aa83839dddb6c53cff9fb9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9062528610229492}","{'position': 2, 'link': 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is as safe and effective \nas the twice-weekly regimen used for the initial treatment of multiple \nmyeloma...', 'thumbnail': 'https://serpapi.com/searches/6723d7a90053c76d043be7ce/images/fe3694714c112ff965248224f45ba2fc1f11b86105ec588a4ad583324087f5f1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5886017084121704}",,,,,,,,,,['neutral'],neutral,1 NCT05279131,"{'position': 1, 'link': 'https://www.empr.com/home/news/klisyri-approved-to-treat-actinic-keratosis-over-larger-surface-areas/', 'title': 'Klisyri Approved to Treat Actinic Keratosis Over Larger Surface Areas', 'source': 'Medical Professionals Reference', 'date': 'Jun 10, 2024', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of Klisyri \n(tirbanibulin) to include the treatment of actinic keratosis on areas of \nthe face...', 'thumbnail': 'https://serpapi.com/searches/6723d7db11db456d905d7916/images/925ba557ff222beee66b8230ad80f0ecf8c5dbe9df3f2bec9e52e81a953792ac.jpeg', 'sentiment': 'neutral', 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clinical outcomes.', 'thumbnail': 'https://serpapi.com/searches/6723d7f90be2f6aacef183d7/images/181d0bbe50437b78d4d3bc0d697a04e21a1ba3b7f854e29da8fca42c8e2e36de.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8579881191253662}","['neutral', 'neutral', 'neutral', 'neutral', 'positive', 'neutral', 'negative', 'neutral', 'neutral', 'neutral']",neutral,1 NCT02072070,"{'position': 1, 'link': 'https://www.nature.com/articles/s41536-018-0055-2', 'title': 'Trends in clinical trials for articular cartilage repair by cell therapy', 'source': 'Nature', 'date': 'Oct 11, 2018', 'snippet': 'In this study, we examined the clinical research trends related to cell \ntherapy products in the cartilage repair field based on data obtained from \nthe...', 'thumbnail': 'https://serpapi.com/searches/6723d80b6f9f63a05efdfada/images/540d6187a68b9118093f7fe0dde6ad327ca5c8cf8005cc062279d78e2ef17ddf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9175892472267151}",,,,,,,,,,['neutral'],neutral,1 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'snippet': 'Following an agreement with Pfizer, Axsome Therapeutics now has exclusive \nrights to develop and commercialize AXS-14 (esreboxetine) — a drug...', 'thumbnail': 'https://serpapi.com/searches/6723d898fbde0d882067e606/images/27f4f0031ce970a627d2df8a4bf6fef8ce26a353e99958ea6a6e67244487cad6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8637092709541321}",,,,,,,,,,['neutral'],neutral,1 NCT03077685,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20231010850022/en/Interim-Results-from-a-NanOlogy-Phase-2-Clinical-Trial-of-its-Intratumoral-Investigational-Drug-in-the-Treatment-of-Locally-Advanced-Pancreatic-Cancer', 'title': 'Interim Results from a NanOlogy Phase 2 Clinical Trial of its Intratumoral Investigational Drug in the Treatment of Locally Advanced Pancreatic Cancer', 'source': 'Business Wire', 'date': 'Oct 10, 2023', 'snippet': 'Research article published in Pancreas Journal reports initial safety and \nclinical outcome data from a Phase 2a clinical 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NCT02228369,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.19.00457', 'title': 'Osimertinib in Patients With Epidermal Growth Factor Receptor Mutation–Positive Non–Small-Cell Lung Cancer and Leptomeningeal Metastases: The BLOOM Study', 'source': 'ASCO Publications', 'date': 'Dec 6, 2019', 'snippet': 'PURPOSEIn this phase I study (BLOOM), osimertinib, a third-generation \nepidermal growth factor receptor (EGFR) tyrosine kinase inhibitor...', 'thumbnail': 'https://serpapi.com/searches/6723d8c77ca6b38082a7f69a/images/46848478050de8ffdb306a9cbc10c058b25a16bda5884853a895f043562035f5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8860406875610352}","{'position': 2, 'link': 'https://lungcancernewstoday.com/2017/06/15/phase-3-trial-shows-70-percent-of-brain-cancer-originating-in-lungs-responds-to-tagrisso/', 'title': '70% of Patients with Brain Cancer Originating in the Lungs Responded to Tagrisso, Trial Shows', 'source': 'Lung Cancer News Today', 'date': 'Jun 15, 2017', 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with corticosteroids for the treatment of \neosinophilic granulomatosis with polyangiitis, a study says.', 'thumbnail': 'https://serpapi.com/searches/6723d9297c1712ec9a29f48f/images/d4351ccd7f9550e526337c8b220749bba84905c02260bae5cfbe762dc3cfb0a6.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7394481301307678}",,,,,,,,"['neutral', 'positive', 'positive']",positive,1 NCT00938912,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Vimpat-lacosamide', 'title': 'Lacosamide (Vimpat®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Epilepsy, A Study to Evaluate the Efficacy and Safety of Adjunctive Therapy \nWith Lacosamide in Adults With Partial Onset Seizures, Phase 3...', 'thumbnail': 'https://serpapi.com/searches/6723d939707fd33e0a051dcc/images/5899963e45e9c379ba8f2967e54e0908095cdca0b5574791361ccaf36d40022b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9128645658493042}",,,,,,,,,,['neutral'],neutral,1 NCT02187003,"{'position': 1, 'link': 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2 Years Following Administration', 'source': 'Pharmacy Times', 'date': '1 month ago', 'snippet': 'The investigators of the phase 3b trial (NCT04838444) will continue to \nfollow up with patients for up to 10 years.', 'thumbnail': 'https://serpapi.com/searches/6723da20c821271837d7b109/images/564ca8cc39920bf0df418ed607971b4304525e59a0525e5de5a2b021e479e18f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8918190598487854}","{'position': 3, 'link': 'https://www.europeanpharmaceuticalreview.com/news/159755/chikungunya-vaccine-effective-in-98-5-percent-of-participants/', 'title': 'Chikungunya vaccine effective in 98.5 percent of participants', 'source': 'European Pharmaceutical Review', 'date': 'Aug 6, 2021', 'snippet': ""Valneva's single-shot chikungunya vaccine induced neutralising antibody \ntiters in 98.5 percent of participants in a Phase III study."", 'thumbnail': 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tested in CDM1 children in a clinical \ntrial, showed promise in a Duchenne MD mouse model.', 'thumbnail': 'https://serpapi.com/searches/6723da0717a2e2703ff743a6/images/450026c21baaee867ba188d434720174185178a1dad7cda101dc748dbbba4382.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7822775840759277}",,,,,,,,,,['neutral'],neutral,1 NCT03355365,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/04/25/aan-2023-stem-cell-therapy-aids-walking-progressive-ms/', 'title': 'AAN 2023: MSC-NP aids walking in advanced progressive MS patients', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 25, 2023', 'snippet': 'Primary and secondary progressive MS patients with EDSS scores of 6-6.5 \nshowed walking ability gains after MSC-NP treatment in Phase 2...', 'thumbnail': 'https://serpapi.com/searches/6723da0717b10e8d8c777066/images/0078dcfebd805361b1a03b64ce335195e8b5f345eb389ec13a0f1b4407df22ba.png', 'sentiment': 'neutral', 'sentiment_prob': 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Sadiq, MD, FAAN', 'source': 'Neurology live', 'date': 'May 8, 2023', 'snippet': 'The director and chief research scientist at Tisch MS Research Center of \nNew York talked about a phase 2 data study on stem cell treatment...', 'thumbnail': 'https://serpapi.com/searches/6723da0717b10e8d8c777066/images/0078dcfebd8053615330b55b91f1a8743414f60e24ad3a5870178267a48fe6e5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.92734295129776}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02142738,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1606774', 'title': 'Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 9, 2016', 'snippet': 'In this open-label, phase 3 trial, we randomly assigned 305 patients who \nhad previously untreated advanced NSCLC with PD-L1 expression on at...', 'thumbnail': 'https://serpapi.com/searches/6723da0b7ac7318c72f6d958/images/83941f527f73ed05b303e979d1216bd4cce5478c6e971abe5c102f28977f80d2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9094976782798767}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/new-5-year-keynote-024-data-show-pembrolizumab-continues-to-prolong-os-in-nsclc', 'title': 'New 5-Year KEYNOTE-024 Data Show Pembrolizumab Continues to Prolong OS in NSCLC', 'source': 'Cancer Network', 'date': 'May 11, 2021', 'snippet': 'New 5-year data from the closely watched KEYNOTE-024 trial (NCT02142738) \nshow pembrolizumab (Keytruda) roughly doubles 5-year overall survival (OS) \nrates.', 'thumbnail': 'https://serpapi.com/searches/6723da0b7ac7318c72f6d958/images/83941f527f73ed05a8f2f9de3a886efa2949d397c293a386b8e779365e138ab1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8887069225311279}","{'position': 3, 'link': 'https://immuno-oncologynews.com/2017/09/27/first-line-lung-cancer-treatment-keytruda-approved-in-canada/', 'title': 'Keytruda Approved as First-Line Lung Cancer Treatment in Canada', 'source': 'Immuno-Oncology News', 'date': 'Sep 27, 2017', 'snippet': ""Canadian patients with metastatic non-small cell lung cancer (NSCLC) can \nnow receive Merck's Keytruda (pembrolizumab) as their first..."", 'thumbnail': 'https://serpapi.com/searches/6723da0b7ac7318c72f6d958/images/83941f527f73ed052b1cd52a9686bc56935b98acb4d7c7c59f1b98094fc60a78.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.750982940196991}","{'position': 4, 'link': 'https://lungcancernewstoday.com/2017/06/13/update-shows-lung-cancer-therapy-keytruda-outperforms-standard-chemo/', 'title': 'Lung Cancer Therapy Keytruda Outperforms Standard Chemo, Update Shows', 'source': 'Lung Cancer News Today', 'date': 'Jun 13, 2017', 'snippet': 'Read about an update of a Phase 3 clinical trial showing that Keytruda \noutperforms standard chemo as a treatment for non-small cell lung...', 'thumbnail': 'https://serpapi.com/searches/6723da0b7ac7318c72f6d958/images/83941f527f73ed05affbd45d4580e0b21e9a979fa9ad2438ae57c250a0f56937.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8445651531219482}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00004067,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa052122', 'title': 'Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Oct 20, 2005', 'snippet': 'We present the combined results of two trials that compared adjuvant \nchemotherapy with or without concurrent trastuzumab in women with...', 'thumbnail': 'https://serpapi.com/searches/6723da0cf963e7cdccd22b0a/images/040e5fc8681d6245bde28fde8d5787a6fca92921a3a77d2e3af096f17dc8b437.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9143195152282715}",,,,,,,,,,['neutral'],neutral,1 NCT03043313,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/reports/tucatinib-trastuzumab-her2-metastatic-crc/', 'title': 'Tucatinib Plus Trastuzumab Shows ""Clinically Meaningful"" Activity in HER2+ Metastatic CRC', 'source': 'Cancer Therapy Advisor', 'date': 'Jun 18, 2024', 'snippet': 'Treatment with tucatinib and trastuzumab can produce durable responses in \nadults with previously treated, HER2-positive, RAS-wildtype, unresectable \nor...', 'thumbnail': 'https://serpapi.com/searches/6723d965e1d1ad99be01b879/images/83388c52a3093f73095aaaec97595b0734f42f8d77623f04dcdf535c52df2a4d.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6085677742958069}",,,,,,,,,,['positive'],positive,1 NCT01292603,"{'position': 1, 'link': 'https://www.nature.com/articles/bjc2013371', 'title': 'Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase', 'source': 'Nature', 'date': 'Sep 3, 2013', 'snippet': 'Rituximab and trastuzumab were the first therapeutic monoclonal antibodies \n(mAbs) approved in oncology. Both antibodies are delivered by the...', 'thumbnail': 'https://serpapi.com/searches/6723d9722c83d5927f338d85/images/9f7dd113710194d79e6a7c647a4b6dfbc4da626be22b5572907e838d90b46044.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.807932436466217}",,,,,,,,,,['neutral'],neutral,1 NCT02274155,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-21383-1', 'title': 'Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells', 'source': 'Nature', 'date': '١٦\u200f/٠٢\u200f/٢٠٢١', 'snippet': 'Despite the success of checkpoint blockade in some cancer patients, there \nis an unmet need to improve outcomes.', 'thumbnail': 'https://serpapi.com/searches/6723d9a45f97789cdc77acab/images/0ed67b8c91fa31eae8661318cae98f847565a0b33018169ec3b648ccead1e6dd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.645016610622406}",,,,,,,,,,['neutral'],neutral,1 NCT02329327,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.057844', 'title': 'Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors', 'source': 'American Heart Association Journals', 'date': 'Feb 20, 2023', 'snippet': 'Background:Andexanet alfa is a modified recombinant inactive factor Xa \n(FXa) designed to reverse FXa inhibitors. 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Goy, MD, discusses how the ZUMA-18 trial data support the benefit \nof earlier-line use of brexucabtagene autoleucel in mantle cell...', 'thumbnail': 'https://serpapi.com/searches/6723dabb08abe4f8e76af46d/images/c1295e64d1cb7847cdd8e75ba5e68aeefbe192e3aa183db2b47385acc5e8998d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.581397533416748}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1914347', 'title': 'KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma', 'source': 'The New England Journal of Medicine', 'date': 'Apr 1, 2020', 'snippet': 'KTE-X19, an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, may \nhave benefit in patients with relapsed or refractory mantle-cell lymphoma.', 'thumbnail': 'https://serpapi.com/searches/6723dabb08abe4f8e76af46d/images/c1295e64d1cb78474e5da3305af7e91cf8ad91257acd3b78373b32b51d959b4a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8843450546264648}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02682927,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Fenfluramine%20%20%28Fintepla%29', 'title': 'Fenfluramine (Fintepla)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Dravet Syndrome, A Study to Evaluate Safety, Tolerability, and \nPharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to \nLess...', 'thumbnail': 'https://serpapi.com/searches/6723dabdd16915e4d3acc90e/images/051c791fed0f8e09ca5b5258708b9b90e13090f4e9ae1ed3d88bc399568e8579.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8484590649604797}","{'position': 2, 'link': 'https://dravetsyndromenews.com/news/finteplas-potential-dual-mechanism-of-action-may-explain-effectiveness-at-reducing-seizures-in-dravet-syndrome/', 'title': 'Fintepla Fares Well in Study of Seizure Reduction in Dravet Syndrome', 'source': 'Dravet Syndrome News', 'date': 'Apr 14, 2020', 'snippet': 'The potential dual mechanism of action of Fintepla may explain its strong \nand durable effectiveness at reducing seizures in patients with...', 'thumbnail': 'https://serpapi.com/searches/6723dabdd16915e4d3acc90e/images/051c791fed0f8e097abbb396409486dc859c5d2cd1597a2eb451a3128ca5f546.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5350711345672607}","{'position': 3, 'link': 'https://dravetsyndromenews.com/news/zx008-receives-fda-breakthrough-therapy-designation-dravet-syndrome/', 'title': 'Investigative Antiepileptic ZX008 Receives FDA’s Breakthrough Therapy Tag', 'source': 'Dravet Syndrome News', 'date': 'Feb 22, 2018', 'snippet': 'The US Food and Drug Administration has granted breakthrough therapy \ndesignation to ZX008 to treat seizures associated with Dravet syndrome.', 'thumbnail': 'https://serpapi.com/searches/6723dabdd16915e4d3acc90e/images/051c791fed0f8e098564cbfe4c7077c823787725355fbd99af10541b69db07bf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7138826251029968}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04181723,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02398-1', 'title': 'Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study', 'source': 'Nature', 'date': 'Jun 8, 2023', 'snippet': 'Rett syndrome is a rare, genetic neurodevelopmental disorder. 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the adverse effects of conventional chemotherapy, \ninhibits PARP, and has antitumor activity in cancer associated with the \nBRCA1 or BRCA2...', 'thumbnail': 'https://serpapi.com/searches/6723dbd8c76a22c3c0f854e6/images/1b1ce13fccbd901dd85c317cdf9a22fcb9ec1085dd2ef26eebf988a85dd58246.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7652683854103088}",,,,,,,,,,['neutral'],neutral,1 NCT00000611,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/news/calcium-vitamin-d-supplement-use-cancer-mortality/', 'title': 'Calcium and Vitamin D Supplement Use Decreases Cancer Mortality', 'source': 'Endocrinology Advisor', 'date': 'Apr 18, 2024', 'snippet': 'Calcium and vitamin D supplementation is associated with decreased overall \ncancer mortality but increased cardiovascular disease (CVD)...', 'thumbnail': 'https://serpapi.com/searches/6723dbd96f9f63a00dd9b71f/images/27dc6f8952795b01c5a7bf592f5940264f01110b016dd4e635dada683cac7601.png', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'Humanetics Corporation (Humanetics) announced the publication of two \nnoteworthy manuscripts detailing the development of BIO 300 as a...', 'thumbnail': 'https://serpapi.com/searches/6723dbdbf963e7ce0fc7db47/images/3de9a2b71df1250907de42467c2a4c5459296851d9ecf01e7eac556af105a08e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8621382117271423}",,,,,,,,,,['neutral'],neutral,1 NCT03230318,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0334-0', 'title': 'Derazantinib (ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive intrahepatic cholangiocarcinoma', 'source': 'Nature', 'date': 'Nov 13, 2018', 'snippet': 'Next-generation sequencing has identified actionable genetic aberrations in \nintrahepatic cholangiocarcinomas (iCCA), including the...', 'thumbnail': 'https://serpapi.com/searches/6723dbf07ac7318c72f6d9df/images/392e314e7efcc16c5fdb09f341c1e00250676af388947411e6faaf12e63323e2.png', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': ""The US Food & Drug Administration (FDA) has tentatively approved Alembic \nPharmaceuticals' generic formulation of injectable selexipag as a treatment \nfor..."", 'thumbnail': 'https://serpapi.com/searches/6723dc1f88bcde1b95c7ca80/images/72c912d51c7c8374806900049ee2532fa927af990bd7aeb76b16e08c1e812885.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9098172783851624}",,,,,,,,,,['neutral'],neutral,1 NCT03300050,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-022-00583-w', 'title': 'Transcriptome signatures preceding the induction of anti-stalk antibodies elicited after universal influenza vaccination', 'source': 'Nature', 'date': 'Dec 10, 2022', 'snippet': 'A phase 1 clinical trial to test the immunogenicity of a chimeric group 1 \nHA (cHA) universal influenza virus vaccine targeting the conserved...', 'thumbnail': 'https://serpapi.com/searches/6723dc1f21b01bd60031052b/images/e082ee5e68ebc0b5d30dc9e869f4aa78ddf5181f8f240377842cd861c968d15a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9300333857536316}",,,,,,,,,,['neutral'],neutral,1 NCT03610334,"{'position': 1, 'link': 'https://alsnewstoday.com/news/boosting-cell-stress-response-may-be-promising-approach-treating-als-phase-2-trial-suggests/', 'title': 'Boosting Cell Stress Response May Be Promising Therapy Approach', 'source': 'ALS News Today', 'date': 'May 6, 2021', 'snippet': 'Boosting the unfolded protein response, a cellular stress-response \nmechanism, may slow disease progression in early ALS patients,...', 'thumbnail': 'https://serpapi.com/searches/6723dc882bab90360de140ac/images/d1e1643ee2afd25bdd6c8befc3204dfdde235f728f31d07b50df53575b9419f4.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7019141912460327}",,,,,,,,,,['positive'],positive,1 NCT02268552,"{'position': 1, 'link': 'https://smanewstoday.com/news/novartis-stopping-development-branaplam-sma-oral-therapy/', 'title': 'Novartis Stopping Work on Branaplam as Oral SMA Therapy', 'source': 'SMA News Today', 'date': 'Jul 26, 2021', 'snippet': 'Novartis is stopping the clinical development of branaplam (LMI070), its \nexperimental oral treatment for spinal muscular atrophy (SMA) being \nevaluated in a...', 'thumbnail': 'https://serpapi.com/searches/6723dcb008abe4f8e76af4f3/images/498563dcb9ff7e97b71bee437e51f8df938da4b410d5921a8e1a9f8133043026.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6980227828025818}",,,,,,,,,,['negative'],negative,0 NCT04529538,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32541-1/fulltext', 'title': 'Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials', 'source': 'The Lancet', 'date': 'Dec 9, 2020', 'snippet': 'Two novel type 2 oral poliovirus vaccine (OPV2) candidates, novel OPV2-c1 \nand novel OPV2-c2, designed to be more genetically stable than the...', 'thumbnail': 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'https://www.dermatologytimes.com/view/final-ecztend-study-results-confirm-long-term-safety-and-efficacy-of-tralokinumab-for-moderate-to-severe-atopic-dermatitis', 'title': 'Final ECZTEND Study Results Confirm Long-Term Safety and Efficacy of Tralokinumab for Moderate-to-Severe Atopic Dermatitis', 'source': 'Dermatology Times', 'date': '5 days ago', 'snippet': 'LEO Pharma announced final results of the phase 3 ECZTEND study \n(NCT03587805) at the Fall Clinical Dermatology Conference .1 The data,...', 'thumbnail': 'https://serpapi.com/searches/6723dcc6b691a7869c2a6feb/images/41730331e68a96bff35f441f20488fd62e398b02fa72311b104424a38158f9dc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.859636127948761}",,,,,,,,,,['neutral'],neutral,1 NCT04878055,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1002/eji.202250010', 'title': 'Neutrophil activation and neutrophil extracellular traps (NETs) in COVID-19 ARDS and immunothrombosis', 'source': 'Wiley Online Library', 'date': 'Oct 14, 2022', 'snippet': 'Neutrophils play a role in the immunopathology SARS-CoV-2 infection by \ntriggering the formation of NETs, producing cytokines including...', 'thumbnail': 'https://serpapi.com/searches/6723dc2e5bb6a2a9d05e94d0/images/2f9a1ea8da2ef9551cd17a95b9231a5e907a383885bc9dfd8ae04e7742a516f5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6651533842086792}",,,,,,,,,,['neutral'],neutral,1 NCT05582629,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00577-7/fulltext', 'title': 'Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study', 'source': 'The Lancet', 'date': 'Nov 22, 2023', 'snippet': 'Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in \nChina: a multicentre, double-blind, phase 3, randomised controlled study', 'thumbnail': 'https://serpapi.com/searches/6723dc3929e6fb4fb01112db/images/0670cb435e8e8fb868a4b700ea0721d0dfcf73d4a3a58cff071808804a0ec077.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8359487056732178}",,,,,,,,,,['neutral'],neutral,1 NCT05105035,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2022/09/28/2524718/33448/en/Idera-Pharmaceuticals-Acquires-Aceragen.html', 'title': 'Idera Pharmaceuticals Acquires Aceragen', 'source': 'GlobeNewswire', 'date': 'Sep 28, 2022', 'snippet': 'Acquisition includes late-stage rare disease portfolio with anticipated \n2023 clinical milestones and first potential product approval as early as \nlate 2024.', 'thumbnail': 'https://serpapi.com/searches/6723dc6bfc40bf31d0398afa/images/13af37850bb6f51d120e408e99ab3005253ee7d12d6c601df7a375972868dd8b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8883594870567322}",,,,,,,,,,['neutral'],neutral,1 NCT02694328,"{'position': 1, 'link': 'https://www.empr.com/home/news/lybalvi-approved-for-schizophrenia-bipolar-i-disorder/', 'title': 'Lybalvi Approved for Schizophrenia, Bipolar I Disorder', 'source': 'Medical Professionals Reference', 'date': 'Jun 2, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Lybalvi™ (olanzapine \nand samidorphan) for the treatment of schizophrenia,...', 'thumbnail': 'https://serpapi.com/searches/6723dc7a2b5fa7541e6e4df6/images/2cacb057793e35bca8b56bfae319d462b5cd0c1cfac897dba492842d3e4c4df8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8041929006576538}",,,,,,,,,,['neutral'],neutral,1 NCT02005471,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1713976', 'title': 'Venetoclax–Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Mar 21, 2018', 'snippet': 'Venetoclax inhibits BCL2, an antiapoptotic protein that is pathologically \noverexpressed and that is central to the survival of chronic...', 'thumbnail': 'https://serpapi.com/searches/6723dce306f4f25c8742cf96/images/ed0f910ef84ebde3a2f71240052ca2c82fb578ef3b36dfb7f79887de7470e88f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8034161925315857}",,,,,,,,,,['neutral'],neutral,1 NCT02538536,"{'position': 1, 'link': 'https://lungdiseasenews.com/2017/10/26/ipf-therapy-ofev-shows-long-term-effectiveness-regardless-of-baseline-lung-function-early-analysis/', 'title': 'Early Analysis of Ofev in INPULSIS-ON Trial Shows Long-Term Effectiveness in Treating IPF', 'source': 'Lung Disease News', 'date': 'Oct 26, 2017', 'snippet': 'Read about how Ofev (nintedanib) was shown to slow down IPF progression \nregardless of baseline lung function in the Phase 3 INPULSIS...', 'thumbnail': 'https://serpapi.com/searches/6723dcea0377562eb44f3432/images/da7248cb7119cd18a0deef712f7a422c987ea35edfc6608484473efefe99d9d6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6172102093696594}","{'position': 2, 'link': 'https://lungdiseasenews.com/2018/02/21/pbi-4050-pulmonary-fibrosis-targets-new-antifibrotic-pathway/', 'title': 'PF Therapy PBI-4050 Targets New Antifibrotic Pathway, Study Shows', 'source': 'Lung Disease News', 'date': 'Feb 21, 2018', 'snippet': ""PBI-4050, Prometics' lead therapy candidate, targets a new antifibrotic \npathway by regulating two receptors that play an opposite role in..."", 'thumbnail': 'https://serpapi.com/searches/6723dcea0377562eb44f3432/images/da7248cb7119cd1892a39a3efe8b3c83ca94f174af2ca799e5caa9d7114e37ad.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9064428210258484}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05415462,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-39376-7', 'title': 'Safety and immunogenicity of a phase 1/2 randomized clinical trial of a quadrivalent, mRNA-based seasonal influenza vaccine (mRNA-1010) in healthy adults: interim analysis', 'source': 'Nature', 'date': 'Jun 19, 2023', 'snippet': 'Despite vaccine availability, influenza remains a substantial global public \nhealth concern. Here, we report interim findings on the primary...', 'thumbnail': 'https://serpapi.com/searches/6723dd4eef60cb9afd658a6d/images/451ac8fb865d96cafd252b415ecf45c37f1504fe4258d76b4fdbe114e2672503.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8802207112312317}",,,,,,,,,,['neutral'],neutral,1 NCT03607838,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/intradiscal-injection-of-condoliase-looks-promising-for-lumbar-herniation/', 'title': 'Intradiscal Injection of Condoliase Looks Promising for Lumbar Herniation', 'source': 'Medical Professionals Reference', 'date': 'May 26, 2023', 'snippet': 'Topline results were announced from a phase 3 trial evaluating SI-6603 \n(condoliase), an investigational treatment for lumbar disc...', 'thumbnail': 'https://serpapi.com/searches/6723dd59861b9d3920a7a60f/images/18fa1cb2a498f531396a582be696e48a3173b160a9ec10545e69bbd467eb0074.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.697502076625824}","{'position': 2, 'link': 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with...', 'thumbnail': 'https://serpapi.com/searches/6723ddcd5a461a60b367e2c6/images/4c71566c8dde80e0d63b46284d9f471da8ae6af0f9c596931bf74306c82beb69.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.539388120174408}",,,,,,,,,,['positive'],positive,1 NCT02655952,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-021-00701-5', 'title': 'Wnt/β-catenin signaling in cancers and targeted therapies', 'source': 'Nature', 'date': 'Aug 30, 2021', 'snippet': 'In this study, we systematically reviewed the most updated knowledge of \nWnt/β-catenin signaling in cancers and relatively targeted therapies.', 'thumbnail': 'https://serpapi.com/searches/6723ddd41fc7c5f7684d276a/images/008a0ed8a9d34c5a19d9921208bc6d70474deada9bdc9a194bfce42d8513ad5c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9130144715309143}",,,,,,,,,,['neutral'],neutral,1 NCT01194219,"{'position': 1, 'link': 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'National Institute on Aging (.gov)', 'date': 'Jun 16, 2022', 'snippet': 'Preliminary results from an NIH-funded clinical trial appear to show that \nan investigational anti-amyloid drug, crenezumab, did not...', 'thumbnail': 'https://serpapi.com/searches/6723e1950f2a2cff75e55802/images/f1afd30f51df6ecd55f2774e2c282e89520db118af2434efd99b47904e7e89e8.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5876600742340088}",,,,,,,,,,['negative'],negative,0 NCT03524170,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-019-0133-7', 'title': 'If we build it they will come: targeting the immune response to breast cancer', 'source': 'Nature', 'date': 'Oct 29, 2019', 'snippet': 'Historically, breast cancer tumors have been considered immunologically \nquiescent, with the majority of tumors demonstrating low lymphocyte...', 'thumbnail': 'https://serpapi.com/searches/6723e1a317b10e8d8c777228/images/911992f750464a94864a840f5e5102fe6cfe1f51369f1f3c193ff6abbd96fce1.jpeg', 'sentiment': 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'snippet': 'Semaglutide reduced the risk of clinically important kidney outcomes and \ndeath from cardiovascular causes in patients with type 2 diabetes and \nchronic kidney...', 'thumbnail': 'https://serpapi.com/searches/6723df6ef7adbffe3f0d89fa/images/057e2ea37812ebd9144fd582946d15c3a1718447f6f9f3acdae554aa4d9d397f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.747295618057251}","{'position': 3, 'link': 'https://www.nature.com/articles/s41591-024-03133-0', 'title': 'Effects of semaglutide with and without concomitant SGLT2 inhibitor use in participants with type 2 diabetes and chronic kidney disease in the FLOW trial', 'source': 'Nature', 'date': 'Jun 24, 2024', 'snippet': 'People with type 2 diabetes and chronic kidney disease have a high risk for \nkidney failure and cardiovascular (CV) complications.', 'thumbnail': 'https://serpapi.com/searches/6723df6ef7adbffe3f0d89fa/images/057e2ea37812ebd9ce3fee4614eafd992edd8c88f30031453e52076bb40283d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7017889022827148}","{'position': 4, 'link': 'https://www.pharmacypracticenews.com/Clinical/Article/10-24/Pharm-Capsules/75038', 'title': 'Pharm Capsules', 'source': 'Pharmacy Practice News', 'date': '4 weeks ago', 'snippet': 'The glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide helps \nprevent the progression of chronic kidney disease in patients with type 2 \ndiabetes.', 'thumbnail': 'https://serpapi.com/searches/6723df6ef7adbffe3f0d89fa/images/057e2ea37812ebd9b752ba63bb2b03b1076e512c7a74d746c18f1a87d1d6ce57.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7873850464820862}","{'position': 5, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/semaglutide-kidney-outcomes-trial-ends-early/', 'title': 'Semaglutide Kidney Outcomes Trial Ends Early; Findings Appear Positive - MPR', 'source': 'Medical Professionals Reference', 'date': 'Oct 11, 2023', 'snippet': 'Novo Nordisk has stopped its phase 3 FLOW trial evaluating semaglutide on \nthe 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Patients May Need a Shorter Chemotherapy Course, International Study Finds', 'source': 'Colon Cancer News Today', 'date': 'Jun 6, 2017', 'snippet': 'Chemotherapy following surgery could be reduced from six to three months in \ncertain colon cancer patients, according to an analysis of over...', 'thumbnail': 'https://serpapi.com/searches/6723e15e49ea55e4487da6f3/images/0b5fdd1c66d03a0a2708597ca46b9ad2cc64ec7258273d0a34bce97dffa59c31.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.738676130771637}",,,,,,,,,,['neutral'],neutral,1 NCT04546425,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20240306876116/en/European-Commission-Approves-Pfizer%E2%80%99s-PREVENAR-20%C2%AE-to-Help-Protect-Infants-and-Children-Against-Pneumococcal-Disease', 'title': 'to Help Protect Infants and Children Against Pneumococcal Disease', 'source': 'Business Wire', 'date': 'Mar 13, 2024', 'snippet': ""The European Commission (EC) has granted marketing authorization for the \ncompany's 20-valent pneumococcal conjugate vaccine, marketed in the \nEuropean Union..."", 'thumbnail': 'https://serpapi.com/searches/6723e175e95dbfe4d9d2a3c1/images/c43e532f6ba23b1116fd4cff5d766a21aa6e1ad1a206168a7546b26ffa2d2289.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8275774717330933}","{'position': 2, 'link': 'https://www.indianpharmapost.com/drug-approval/european-commission-approves-pfizers-prevenar-20-to-help-protect-infants-and-children-against-pneumococcal-disease-15390', 'title': 'European Commission approves Pfizer’s Prevenar 20 to help protect infants and children against pneumococcal disease', 'source': 'Indian Pharma Post', 'date': 'Mar 13, 2024', 'snippet': 'PREVENAR offers the broadest serotype coverage of any pediatric \npneumococcal conjugate vaccine to help protect infants and children from \nthe 20 serotypes.', 'thumbnail': 'https://serpapi.com/searches/6723e175e95dbfe4d9d2a3c1/images/c43e532f6ba23b110b7e894141a456b377e596ad15d444de332261360ec0383e.png', 'sentiment': 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'Jul 20, 2018', 'snippet': 'Based on our previous study of the combination of sorafenib with \n5-azacytidine (AZA) in relapsed/refractory patients with FLT3 mutated acute \nmyeloid leukemia (...', 'thumbnail': 'https://serpapi.com/searches/6723de0ecaddc3538c8557db/images/c75e1187d6c625c4a55bc51b326494d07f80bb94e3230296c5dac6faa23c48c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.834568440914154}",,,,,,,,,,['neutral'],neutral,1 NCT02473289,"{'position': 1, 'link': 'https://www.nature.com/articles/s41380-019-0471-8', 'title': 'Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders', 'source': 'Nature', 'date': 'Aug 19, 2019', 'snippet': 'Novel immune-therapeutics can produce antidepressant effects in depressed \npatients with primary inflammatory disorders that are not entirely \nexplained by...', 'thumbnail': 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In the ongoing phase 2 MagnetisMM-3 trial,...', 'thumbnail': 'https://serpapi.com/searches/6723de17717bffe990a03cad/images/bbc6cf1bb66bd969fa40b97042a2f760bb6d2b0021416cb21a9b985ccf40b6e7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9085099101066589}",,,,,,,,,,['neutral'],neutral,1 NCT02141672,"{'position': 1, 'link': 'https://www.rheumatologyadvisor.com/features/belimumab-or-voclosporin-for-lupus-nephritis-debated-by-michelle-petri-brad-rovin-at-acr-2021/', 'title': 'ACR 2021 Debate: Enhancing Standard Lupus Nephritis Therapy With Belimumab or Voclosporin', 'source': 'Rheumatology Advisor', 'date': 'Nov 12, 2021', 'snippet': 'Lupus nephritis (LN) is known to affect approximately 40% of patients with \nsystemic lupus erythematous (SLE),1 with kidney disease being one...', 'thumbnail': 'https://serpapi.com/searches/6723de18ef60cb9afd658a9f/images/0276fd5a5d988b69290a26ed156ecfa28ee91c34c8b9564725d4dcf9ee8be2d3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7611857056617737}",,,,,,,,,,['neutral'],neutral,1 NCT03525600,"{'position': 1, 'link': 'https://www.ophthalmologytimes.com/view/asrs-live-a-novel-glyco-mimetic-nanoparticle-for-the-treatment-of-geographic-atrophy', 'title': 'ASRS Live: A novel glyco-mimetic nanoparticle for the treatment of geographic atrophy', 'source': 'Ophthalmology Times', 'date': 'Aug 2, 2023', 'snippet': 'Tarek Hassan, MD, spoke with our team about a novel glyco-mimetic \nnanoparticle for the treatment of geographic atrophy at the 2023 ASRS...', 'thumbnail': 'https://serpapi.com/searches/6723de36f3622a497245938a/images/11f769b942d01fa6b38d67bec186cbebc56dc51148f71707b50412acfae0afdb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9001842141151428}","{'position': 2, 'link': 'https://www.empr.com/home/news/syfovre-approved-for-geographic-atrophy-secondary-to-amd/', 'title': 'Syfovre Approved for Geographic Atrophy Secondary to AMD', 'source': 'Medical Professionals Reference', 'date': 'Feb 21, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Syfovre™ (pegcetacoplan \ninjection, for intravitreal use) for the treatment of geographic...', 'thumbnail': 'https://serpapi.com/searches/6723de36f3622a497245938a/images/11f769b942d01fa6863253a08b4e081c4a155ebd9633c3ffa3cc10fa54840ac6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8288508653640747}","{'position': 3, 'link': 'https://www.ophthalmologytimes.com/view/asrs-2023-pegcetacoplan-vs-avacincaptad-pegol-in-patients-with-geographic-atrophy', 'title': 'ASRS 2023: Pegcetacoplan vs avacincaptad pegol in patients with geographic atrophy', 'source': 'Ophthalmology Times', 'date': 'Aug 4, 2023', 'snippet': 'Paul Hahn, MD, PhD, spoke with our team about comparing the relative \nefficacy of pegcetacoplan versus avacincaptad pegol in patients with...', 'thumbnail': 'https://serpapi.com/searches/6723de36f3622a497245938a/images/11f769b942d01fa695fff27ffe6f0f2fe3e1d5b624f3da45b203ee1d46c1bed9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9235212802886963}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02139267,"{'position': 1, 'link': 'https://cervicalcancernews.com/2016/11/18/genexine-merck-collaborate-clinical-trial-therapy-combo-hpv-induced-cervical-cancer/', 'title': 'Clinical Trial in HPV-induced Cervical Cancer to Evaluate Drug Combo', 'source': 'Cervical cancer News', 'date': 'Nov 18, 2016', 'snippet': 'Read about how Genexine and Merck are collaborating in a clinical trial to \nevaluate a therapy combination for patients with HPV-induced...', 'thumbnail': 'https://serpapi.com/searches/6723de506cca5ed2960d3006/images/7aa2c2adb6f599565310b817555aa58d619eb4a5d3928a2ad4e2701742d9dc1a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9329053163528442}",,,,,,,,,,['neutral'],neutral,1 NCT01007552,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00324-2', 'title': 'Overview of current targeted therapy in gallbladder cancer', 'source': 'Nature', 'date': 'Oct 7, 2020', 'snippet': 'Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary \ntract tumor. Unfortunately, only a small population of cancer...', 'thumbnail': 'https://serpapi.com/searches/6723de67f59d009e78054575/images/0ef7f351577aca28708ade8a229adf09dfabb9ca0c86104990b19c1f449f40c8.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7814876437187195}",,,,,,,,,,['negative'],negative,0 NCT00802347,"{'position': 1, 'link': 'https://www.drugdiscoverytrends.com/quark-pharmaceuticals-reports-positive-phase-2-results-to-evaluate-the-efficacy-and-safety-of-qpi-1002/', 'title': 'Quark Pharmaceuticals Reports Positive Phase 2 Results to Evaluate the Efficacy and Safety of QPI-1002', 'source': 'drugdiscoverytrends.com', 'date': 'Jul 28, 2017', 'snippet': 'Quark Pharmaceuticals announced successful completion of a randomized, \ndouble-blinded, placebo-controlled multicenter Phase 2 trial of...', 'thumbnail': 'https://serpapi.com/searches/6723de68e10f0aab7ad452df/images/32007432b77fe922847a8e27947d4feeb85365796070cfe203a8bfccc52d9989.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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'snippet': 'The use of darbepoetin alfa to treat anemia in patients with lower-risk \nmyelodysplastic syndromes (MDS) was evaluated in a phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/6723df7ed0c98349f3f119f5/images/786d652e25934d736816eb56eefd2575962017493e6ded92d36591a21b8d0db8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9045476913452148}",,,,,,,,,,['neutral'],neutral,1 NCT02926222,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30675-2/fulltext', 'title': 'Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial', 'source': 'The Lancet', 'date': 'Dec 3, 2018', 'snippet': 'Regorafenib compared with lomustine in patients with relapsed glioblastoma \n(REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial', 'thumbnail': 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a functional status decline."", 'thumbnail': 'https://serpapi.com/searches/6723df87e335ec621cd25020/images/a867d5890b9be392b18e8a07dafa24061398107206e6686f9eb73e70fe4c926a.png', 'sentiment': 'negative', 'sentiment_prob': 0.6226062178611755}","{'position': 4, 'link': 'https://musculardystrophynews.com/news/study-upper-limb-function-fshd-improved-stabilized-with-losmapimod/', 'title': 'Losmapimod improved, stabilized FSHD upper limb function: Study', 'source': 'Muscular Dystrophy News', 'date': 'Jul 11, 2024', 'snippet': 'One year of twice daily losmapimod improved or stabilized upper limb \nfunction in adults with facioscapulohumeral muscular dystrophy (FSHD).', 'thumbnail': 'https://serpapi.com/searches/6723df87e335ec621cd25020/images/a867d5890b9be392bdf1838b67fe29c4e01a8b4ca463df8097829886ec632f81.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8635152578353882}","{'position': 5, 'link': 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We compared the \neffect of...', 'thumbnail': 'https://serpapi.com/searches/6723e13ed771bdcb8c632589/images/bf4b188cee1e15bdb9c6738d9e2c22880f86c7737096241535669acc8d7eda16.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8532211780548096}",,,,,,,,,,['neutral'],neutral,1 NCT02931929,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/61/12/1749', 'title': 'MITIGATE-NeoBOMB1, a Phase I/IIa Study to Evaluate Safety, Pharmacokinetics, and Preliminary Imaging of', 'source': 'Journal of Nuclear Medicine', 'date': 'Dec 1, 2020', 'snippet': 'This phase I/IIa study provides safety data for 68 Ga-NeoBOMB1, a promising \nradiopharmaceutical for targeting GRPR-expressing tumors.', 'thumbnail': 'https://serpapi.com/searches/6723e145f9f90497df3e4ad1/images/e5b9f3a8e62a665d5fd3658dd0dfefaef600cdee44815fb778062e8bc7b0d9be.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7982731461524963}",,,,,,,,,,['neutral'],neutral,1 NCT03626012,"{'position': 1, 'link': 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NCT01251367,"{'position': 1, 'link': 'https://cerebralpalsynewstoday.com/2017/06/19/fda-expands-dysport-approval-for-treatment-of-lower-limb-spasticity-in-adults/', 'title': 'FDA Expands Dysport Approval for Treatment of Lower Limb Spasticity in Adults', 'source': 'Cerebral Palsy News Today', 'date': 'Jun 19, 2017', 'snippet': 'The US Food and Drug Administration (FDA) has expanded approval of Dysport \n(abobotulinumtoxinA) for the treatment of lower limb spasticity in adults.', 'thumbnail': 'https://serpapi.com/searches/6723e0318e13c9143cc5b384/images/4d0a7c700ac99c52c57bf9314f2545de7c8b0151bdf5375a012d08c718d30473.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7941434383392334}",,,,,,,,,,['neutral'],neutral,1 NCT04440163,"{'position': 1, 'link': 'https://www.biopharma-reporter.com/Article/2022/09/15/Pfizer-Phase-3-results-for-pentavalent-meningococcal-vaccine', 'title': 'Pfizer: Phase 3 results for pentavalent meningococcal vaccine', 'source': 'biopharma-reporter.com', 'date': 'Sep 15, 2022', 'snippet': 'Pfizer will submit a Biologics License Application (BLA) for its \ninvestigational pentavalent meningococcal vaccine (MenABCWY) to the US \nFood...', 'thumbnail': 'https://serpapi.com/searches/6723e12330dfc1521a48b561/images/db414187439cef6d9eb592d9f2f4486dc65cbc40514735932d77729f2735720e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9041036367416382}",,,,,,,,,,['neutral'],neutral,1 NCT00075764,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1811714', 'title': 'Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Mar 27, 2019', 'snippet': 'The addition of fulvestrant to anastrozole was associated with increased \nlong-term survival as compared with anastrozole alone.', 'thumbnail': 'https://serpapi.com/searches/6723e056d9c3e6603367c235/images/e2e4db6c9529c56b71e4d1bd38ac9b639189f0f5526518144f6b38929f2c3094.png', 'sentiment': 'neutral', 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therapy is a promising new immunotherapy that weaponizes a \npatient's own T cells to fight blood cancers like leukemia & lymphoma."", 'thumbnail': 'https://serpapi.com/searches/6723e0606aa364537522b8b2/images/6496e9c4ffef084e3ccd2a5ae6f5115f5a32eb7c325eb713e13068e40c29d849.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7965629696846008}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03375086,"{'position': 1, 'link': 'https://www.drugtargetreview.com/article/151965/out-of-the-lab-and-into-patients-targeting-ape1-ref-1/', 'title': 'Out of the lab and into patients: targeting APE1/Ref-1', 'source': 'Drug Target Review', 'date': 'Aug 8, 2024', 'snippet': 'Dr Mark R. Kelley elucidates what makes APE1/Ref-1 a promising target for \ncancer therapy.', 'thumbnail': 'https://serpapi.com/searches/6723e0d3c024d1935d72d733/images/6079bb99e8849d5bd1b18449bbf6c5d84d32e708bbdcf6d0ca91c7f657a6bdb3.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5830124616622925}",,,,,,,,,,['positive'],positive,1 NCT01922258,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/schizophrenia-medication-brexpiprazole-lowered-agitation-in-alzheimers-patients-in-phase-3-study/', 'title': ""Alzheimer's Agitation Seen to Ease with Schizophrenia Drug, Brexpiprazole, in Clinical Trial"", 'source': ""Alzheimer's News Today"", 'date': 'May 5, 2017', 'snippet': ""Read about how the schizophrenia medication brexpiprazole seemed to reduce \nsymptoms of agitation in Alzheimer's disease patients."", 'thumbnail': 'https://serpapi.com/searches/6723e0de15c740d14127f744/images/07eb924935c019d7f21c132f0556544e80d9d29a40d83bccec0b470dd850aee5.jpeg', 'sentiment': 'neutral', 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Migraine', 'source': 'Medical Professionals Reference', 'date': 'Jul 6, 2023', 'snippet': 'Zavzpret (zavegepant) nasal spray is now available for the acute treatment \nof migraine with or without aura in adults.', 'thumbnail': 'https://serpapi.com/searches/6723e0dd63a844cf0f6aec1d/images/60333bcdae733f019925f31c7679ff553b34b48ebd832e72b7ef9acf148f2c59.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8405698537826538}","{'position': 2, 'link': 'https://www.empr.com/home/news/zavzpret-nasal-spray-approved-for-acute-treatment-of-migraine/', 'title': 'Zavzpret Nasal Spray Approved for Acute Treatment of Migraine', 'source': 'Medical Professionals Reference', 'date': 'Mar 10, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Zavzpret™ (zavegepant) \nnasal spray, a calcitonin gene-related peptide (CGRP) receptor...', 'thumbnail': 'https://serpapi.com/searches/6723e0dd63a844cf0f6aec1d/images/60333bcdae733f01b75ecff69fddd9fd0396f5647b670911b74140527bc375b9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6946619749069214}","{'position': 3, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/significant-pain-relief-observed-with-intranasal-zavegepant-in-migraine-trial/', 'title': 'Significant Pain Relief Observed With Intranasal Zavegepant in Migraine Trial', 'source': 'Medical Professionals Reference', 'date': 'Dec 6, 2021', 'snippet': 'Topline results were announced from a phase 3 trial evaluating intranasal \nzavegepant for the acute treatment of migraines in adults.', 'thumbnail': 'https://serpapi.com/searches/6723e0dd63a844cf0f6aec1d/images/60333bcdae733f0181d3bd4bd9c85a5d1a6cf1ec8242a7508f954dbb2c710dd8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7664857506752014}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01998971,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-023-00805-x', 'title': 'Daratumumab, carfilzomib, and dexamethasone in relapsed or refractory myeloma: final analysis of PLEIADES and EQUULEUS | Blood Cancer Journal', 'source': 'Nature', 'date': 'Mar 7, 2023', 'snippet': 'We report final data from PLEIADES and EQUULEUS, with a median follow-up of \n12.4 and 23.7 months, respectively.', 'thumbnail': 'https://serpapi.com/searches/6723e0efa88278ea4c0d0526/images/dbcfa68a19d2d76cdd13e36a779704b9621747d9f12dcdb5514ab39c9e0a373c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9076092839241028}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/fda-approves-combo-therapy-that-includes-darzalex-as-multiple-myeloma-treatment/', 'title': 'Multiple Myeloma Combo Therapy That Includes Darzalex Wins FDA Approval', 'source': 'Myeloma Research News', 'date': 'Jun 21, 2017', 'snippet': 'The U.S. Federal Drug Administration approves a combination therapy that \nincludes Darzalex for treating multiple myeloma patients.', 'thumbnail': 'https://serpapi.com/searches/6723e0efa88278ea4c0d0526/images/dbcfa68a19d2d76c2293179f095a9345be7403385106adef2a0ef9153b76d393.jpeg', 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'title': 'Mitochondria and the Many Disorders That Compose ""Mitochondrial...', 'source': 'Mitochondrial Disease News', 'date': 'Aug 26, 2015', 'snippet': 'Mitochondria (singular mitochondrion) are tiny subunits present inside \nevery cell of the human body except red blood cells, from the skin to...', 'thumbnail': 'https://serpapi.com/searches/6723e108b4b72de02896341d/images/7057ae3bbf0748985d3337d5799dbad7a13346c183b44b5ed525e90f566f761f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.889778733253479}",,,,,,,,,,['neutral'],neutral,1 NCT02713178,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/exparel-application-under-review-for-sciatic-and-femoral-nerve-blocks/', 'title': 'Exparel Application Under Review for Sciatic and Femoral Nerve Blocks', 'source': 'Medical Professionals Reference', 'date': 'Mar 31, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted the supplemental New \nDrug Application (sNDA) for Exparel (bupivacaine 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'https://myelomaresearchnews.com/news/once-weekly-kyprolis-effective-untreated-multiple-myeloma-patients/', 'title': 'Once-weekly Kyprolis Safe, Effective for Untreated Multiple Myeloma Patients, Study Finds', 'source': 'Myeloma Research News', 'date': 'Mar 6, 2019', 'snippet': 'Treatment with Kyprolis (carfilzomib) once a week is as safe and effective \nas the twice-weekly regimen used for the initial treatment of multiple \nmyeloma...', 'thumbnail': 'https://serpapi.com/searches/6723e1b2a32436068562daab/images/5e42584e1711a99c9db91b88002fd1ededb878b4af2d9de89e262879661cb0ad.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5886017084121704}",,,,,,,,,,['neutral'],neutral,1 NCT04414345,"{'position': 1, 'link': 'https://alsnewstoday.com/news/long-term-survival-benefit-seen-cnm-au8-healey-als-analyses-trial/', 'title': 'Long-term ALS survival benefit with CNM-Au8 seen in trial analyses...', 'source': 'ALS News Today', 'date': 'Sep 28, 2023', 'snippet': 'New HEALEY ALS trial analyses showed a significant long-term survival \nbenefit for ALS patients treated with CNM-Au8 for up to 2.5 years.', 'thumbnail': 'https://serpapi.com/searches/6723e1b72a48823c174de8a4/images/92104293b7e2214e474d921d55c025be4b89ed789c869289d570658831775383.png', 'sentiment': 'positive', 'sentiment_prob': 0.6370849609375}","{'position': 2, 'link': 'https://alsnewstoday.com/news/cnm-au8-expanded-access-program-will-enroll-more-als-patients/', 'title': 'Clene expanding CNM-Au8 expanded access program in US', 'source': 'ALS News Today', 'date': 'Jun 3, 2024', 'snippet': 'Clene has expanded by 80% the number of ALS patients to be enrolled in a \nsoon-to-launch expanded access program (EAP) for CNM-Au8.', 'thumbnail': 'https://serpapi.com/searches/6723e1b72a48823c174de8a4/images/92104293b7e2214e749cf0f2e258477b1c6fda99bb490c55bfef47fab1126905.png', 'sentiment': 'positive', 'sentiment_prob': 0.7117204666137695}","{'position': 3, 'link': 'https://alsnewstoday.com/news/cnm-au8-delayed-clinical-worsening-als-patients-healey-trial/', 'title': 'CNM-Au8 found to delay clinical worsening in ALS HEALEY trial |...', 'source': 'ALS News Today', 'date': 'Mar 10, 2023', 'snippet': ""Treatment with Clene's CNM-Au8 significantly delayed clinical worsening in \nALS patients participating in an arm of the HEALEY platform..."", 'thumbnail': 'https://serpapi.com/searches/6723e1b72a48823c174de8a4/images/92104293b7e2214ec6a1d38f0f637a28262894ca6251a6b676d106542e932ddf.png', 'sentiment': 'negative', 'sentiment_prob': 0.5408130288124084}",,,,,,,,"['positive', 'positive', 'negative']",positive,1 NCT02644460,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2023.1248753/full', 'title': 'Ewing sarcoma from molecular biology to the clinic', 'source': 'Frontiers', 'date': 'Jun 25, 2024', 'snippet': 'In Europe, with an incidence of 7.5 cases per million, Ewing sarcoma (ES) \nis the second most common primary malignant bone tumor in children,...', 'thumbnail': 'https://serpapi.com/searches/6723e1c13d629b1615675369/images/7400813e35313a175bc10e64a9df558e266724511ec4fcd5d918470c45d3edda.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6943160891532898}",,,,,,,,,,['neutral'],neutral,1 NCT03127514,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1916945', 'title': 'Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 2, 2020', 'snippet': 'Sodium phenylbutyrate–taurursodiol resulted in slower functional decline \nthan placebo as measured by the ALSFRS-R score over a period of 24 weeks.', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda8065808ffb531ca07ebb3ae2e68fc8224021d8ad7e1a0cdd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.63248211145401}","{'position': 2, 'link': 'https://alsnewstoday.com/amx0035/', 'title': 'What is Relyvrio for ALS?', 'source': 'ALS News Today', 'date': 'Apr 11, 2024', 'snippet': 'Relyvrio was an oral treatment approved in the U.S. and Canada for adults \nwith amyotrophic lateral sclerosis that has now been discontinued.', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda7303b884dbb0a5d0030f54935d323dbd1c07b9c37b5bc529.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5614924430847168}","{'position': 3, 'link': 'https://www.pharmaceutical-technology.com/news/amylyx-axes-als-drug-from-market-after-phase-iii-failure/', 'title': 'Amylyx axes ALS drug from market after Phase III failure', 'source': 'Pharmaceutical Technology', 'date': 'Apr 5, 2024', 'snippet': 'Last month, Amylyx announced that the Phase III confirmatory trial of ALS \ndrug Relyvrio failed to meet its primary and secondary endpoints.', 'thumbnail': 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'source': 'ALS News Today', 'date': 'Feb 6, 2023', 'snippet': ""A Phase 3 clinical trial confirming the safety and efficacy of Amylyx's \napproved ALS therapy Relyvrio, formerly AMX0035, is fully enrolled."", 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda72145bd219c89b70c490806397071a98316dd91fff6b9780.png', 'sentiment': 'positive', 'sentiment_prob': 0.5213114023208618}","{'position': 6, 'link': 'https://alsnewstoday.com/news/amx0035-survival-als-patients-centaur-clinical-trial-analysis-amylyx/', 'title': 'AMX0035 Extended Survival in ALS Patients By More Than 10 Months', 'source': 'ALS News Today', 'date': 'May 6, 2022', 'snippet': 'AMX0035 significantly extended median survival by more than 10 months in \nthe Phase 2 CENTAUR clinical trial, a new analysis indicates.', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda5c1fae98a4a9be91970942d1c3b67bf9d504495b8bb6c00d.png', 'sentiment': 'positive', 'sentiment_prob': 0.7468807697296143}","{'position': 7, 'link': 'https://alsnewstoday.com/news/centaur-data-relyvrio-lowers-als-inflammatory-biomarkers/', 'title': 'Relyvrio reduces inflammatory biomarkers in ALS: CENTAUR data', 'source': 'ALS News Today', 'date': 'Dec 18, 2023', 'snippet': 'Treatment with Relyvrio significantly reduced levels of neuroinflammatory \nbiomarkers in the bloodstream of ALS patients after three months.', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda8d2988df105a8ea9e33ace82f793afe7183b6bc3ffac5c15.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5478339195251465}","{'position': 8, 'link': 'https://alsnewstoday.com/news/als-therapies-amx-0035-radicava-ors-may-add-benefit-cost-effective/', 'title': 'AMX0035, Radicava ORS Costs Could Cloud Therapies’ Benefits: ICER', 'source': 'ALS News Today', 'date': 'Aug 9, 2022', 'snippet': 'Note: This story was updated Aug. 10, 2022, to clarify the U.S. Food and \nDrug Administration advisory committee voted there is no...', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda567318592d828b27af0566be9af439d173a79b6010e44aca.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8640235066413879}","{'position': 9, 'link': 'https://alsnewstoday.com/news/amx0035-oral-als-therapy-called-albrioza-approved-canada/', 'title': 'AMX0035, Oral ALS Therapy Now Known as Albrioza, Approved in Canada', 'source': 'ALS News Today', 'date': 'Jun 13, 2022', 'snippet': 'Albrioza, formerly AMX0035, was conditionally approved by Health Canada \nprovided safety and efficacy shown in ongoing Phase 3 PHOENIX trial.', 'thumbnail': 'https://serpapi.com/searches/6723e1cd9062f835cfd4679a/images/d53bb38d36904bda3851cedec66eebac672cd88797fbbedd6230873ce82ae929.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7737936973571777}",,"['neutral', 'neutral', 'negative', 'neutral', 'positive', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03907969,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.998388/full', 'title': 'Anti-cancer immune responses to DNA damage response inhibitors: Molecular mechanisms and progress toward clinical translation', 'source': 'Frontiers', 'date': 'Jun 29, 2023', 'snippet': 'DNA damage response inhibitors are widely used anti-cancer agents that have \npotent activity against tumor cells with deficiencies in various DNA \ndamage...', 'thumbnail': 'https://serpapi.com/searches/6723e1d1a2e99c954cff3ddb/images/3a4f9a463332c947d202669a1b3455e4eac0a83e76ebc7621211d78892b8720e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7443199753761292}",,,,,,,,,,['neutral'],neutral,1 NCT02094573,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/long-term-efficacy-continues-with-brigatinib-in-alk-nsclc-after-crizotinib', 'title': 'Long-Term Efficacy Continues With Brigatinib in ALK+ NSCLC After Crizotinib', 'source': 'Cancer Network', 'date': 'Jun 10, 2021', 'snippet': 'Long-term efficacy and safety results from the phase 1/2 (NCT01449461) and \nphase 2 ALTA (NCT02094573) trials reported at the 2021 American...', 'thumbnail': 'https://serpapi.com/searches/6723e1d5db3ac9f357ce498a/images/2a2ed3f334ccf2f0437c7a928544810808571e1f74bb6871375c0239782c3c7d.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6142606735229492}",,,,,,,,,,['positive'],positive,1 NCT01356498,"{'position': 1, 'link': 'https://www.rheumatologyadvisor.com/news/remission-criteria-validated-new-criteria-defined-for-complete-response-in-chronic-refractory-gout/', 'title': 'Remission Criteria Validated, New Criteria Defined for Complete Response in Chronic Refractory Gout', 'source': 'Rheumatology Advisor', 'date': 'Dec 17, 2019', 'snippet': 'The objective of this study was to generate evidence-based criteria for \ngout remission and develop new criteria for complete response using data \nfrom...', 'thumbnail': 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'title': 'HPV16 infection decreases vaccine-induced HPV16 antibody avidity: the CVT trial', 'source': 'Nature', 'date': 'Mar 29, 2022', 'snippet': 'The HPV vaccine has shown sustained efficacy and consistent stabilization \nof antibody levels, even after a single dose.', 'thumbnail': 'https://serpapi.com/searches/6723e227b2ebaec13d1f0e4b/images/e9bdc0e3831e6bcbd81df12cbe2c53cd8210e8ad1d9045e66f526586ce7774d7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.785798966884613}",,,,,,,,,,['neutral'],neutral,1 NCT03852251,"{'position': 1, 'link': 'https://www.nature.com/articles/s41388-024-03066-5', 'title': 'Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4 - Oncogene', 'source': 'Nature', 'date': 'May 28, 2024', 'snippet': 'The combination of programmed cell death protein 1 (PD-1) and cytotoxic T \nlymphocyte antigen 4 (CTLA-4) antibodies has potential for...', 'thumbnail': 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'title': 'Immunogenicity of CAR-T Cell Therapeutics: Evidence, Mechanism and Mitigation', 'source': 'Frontiers', 'date': 'May 23, 2022', 'snippet': 'Chimeric antigen receptor T cell (CAR-T) therapy demonstrated remarkable \nsuccess in long-term remission of cancers and other autoimmune...', 'thumbnail': 'https://serpapi.com/searches/6723e245d771bdcb8c6325cc/images/ba9d3f1f500b158e2e68efda18a2425de5013448bb6d9d189893f8f8d93301cb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6530438661575317}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-024-52503-2', 'title': 'Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion', 'source': 'Nature', 'date': '1 month ago', 'snippet': 'Chimeric antigen receptor-modified T cell (CAR-T) immunotherapy has \nrevolutionised blood cancer treatment. 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Astellas Pharma US, Inc) became the first medication \nwithin its class to be approved by the US Food and Drug Administration (FDA)', 'thumbnail': 'https://serpapi.com/searches/6723e2a8316650c2f97c9544/images/00637858a2398c39dbc6be691d18fe081722d1b3b61eb17326511d8c6a291552.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7362357974052429}","{'position': 2, 'link': 'https://www.empr.com/home/news/veozah-approved-for-moderate-to-severe-vasomotor-symptoms-due-to-menopause/', 'title': 'Veozah Approved for Moderate to Severe Vasomotor Symptoms Due to Menopause', 'source': 'Medical Professionals Reference', 'date': '15 may 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Veozah™ (fezolinetant) \nfor the treatment of moderate to severe vasomotor symptoms due to...', 'thumbnail': 'https://serpapi.com/searches/6723e2a8316650c2f97c9544/images/00637858a2398c39f20a79f5660a3849fa1ecab16318087d4849177f43f88835.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7814399600028992}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02636582,"{'position': 1, 'link': 'https://breastcancer-news.com/2019/08/19/phase-2-trial-of-sellas-neuvax-vaccine-her2-positive-dcis-breast-cancer-fully-enrolled/', 'title': 'Phase 2 Trial of NeuVax Vaccine for HER2-positive DCIS Fully Enrolled, Sellas Announces', 'source': 'breastcancer-news.com', 'date': 'Aug 19, 2019', 'snippet': ""Early data from the Phase 2 trial evaluating NeuVax in 13 women with early \nstage HER2-positive ductal carcinoma in situ is likely by year's..."", 'thumbnail': 'https://serpapi.com/searches/6723e2b1a5aae9313a6baa93/images/54bffc226ff7c917c595e143f8132cfeac1f8c36e45e98bcafb89827e2c3b853.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9314606785774231}",,,,,,,,,,['neutral'],neutral,1 NCT00436046,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(10)70157-2/abstract', 'title': 'Needle-free influenza vaccination', 'source': 'The Lancet', 'date': 'Nov 1, 2010', 'snippet': 'Vaccination is the cornerstone of influenza control in epidemic and \npandemic situations. 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Measurable residual disease (MRD) is now considered as one of \nthe most important prognostic factors for B cell acute...', 'thumbnail': 'https://serpapi.com/searches/6723e2f9fd3b5abd7063d59b/images/1f5960eb7a604d835b106c215c5d032324215b11253871f1aa080deb1ad3d2de.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9013963341712952}",,,,,,,,,,['neutral'],neutral,1 NCT02756611,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00070-6/fulltext', 'title': 'Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial', 'source': 'The Lancet', 'date': 'Mar 8, 2024', 'snippet': 'Most patients with chronic lymphocytic leukaemia progress after treatment \nor retreatment with targeted therapy or chemoimmunotherapy and...', 'thumbnail': 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'link': 'https://copdnewstoday.com/news/two-trials-demonstrate-rpl554-potential-as-add-on-therapy-for-copd/', 'title': 'Trials Demonstrate RPL554 Has Potential as Add-on Therapy for COPD', 'source': 'COPD News Today', 'date': 'Sep 7, 2018', 'snippet': ""The addition of Verona Pharma's investigational agent RPL554 to standard \nshort- and long-acting bronchodilators offers greater clinical..."", 'thumbnail': 'https://serpapi.com/searches/6723e342993688064fac03d0/images/e69c222211a67adc0c19ba253f60033ca32c21dc7796e82faf91d2ec79b7662a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5002123117446899}","{'position': 2, 'link': 'https://copdnewstoday.com/news/verona-pharma-rpl554-copd-named-ensifentrine/', 'title': 'Verona Pharma’s Candidate RPL554 for COPD Will Be Named Ensifentrine', 'source': 'COPD News Today', 'date': 'Jan 15, 2019', 'snippet': ""The World Health Organization approved the name ensifentrine for Verona \nPharma's investigational bronchodilator and anti-inflammatory agent,..."", 'thumbnail': 'https://serpapi.com/searches/6723e342993688064fac03d0/images/e69c222211a67adc8a757c745f1b62768a560158f7bb480c6e2b8bd7bcfcdb0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8575579524040222}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03697161,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/combination-therapy-gaboxadol-ibudilast-effective-fragile-x-mouse-model/', 'title': 'Combination therapy gaboxadol, ibudilast effective in fragile X mouse model', 'source': 'Fragile X News Today', 'date': 'Mar 1, 2024', 'snippet': 'A combination of ibudilast and gaboxadol was shown to normalize behavior \nand improve memory in a mouse model of fragile X syndrome.', 'thumbnail': 'https://serpapi.com/searches/6723e34898d8de76ab11bb78/images/8d0e875974c34d8ad617f16f5b2864d8c9705bb2caac3bcf867dc17a67240118.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5454389452934265}","{'position': 2, 'link': 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'date': 'Sep 17, 2018', 'snippet': 'An early-stage clinical trial testing the safety and immune-stimulating \nability of an experimental nasal influenza vaccine in healthy 9- to \n17-year-old...', 'thumbnail': 'https://serpapi.com/searches/6723e3e752a04e94a93f192f/images/0892867ef3170a6dd7622257470670946b73b7fbede4c8ad53f020f7a2c6f7e4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8606119155883789}",,,,,,,,,,['neutral'],neutral,1 NCT03976349,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-024-00660-y', 'title': 'G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage', 'source': 'Nature', 'date': 'Mar 1, 2024', 'snippet': ""Pathogenic mutations in LRRK2 cause Parkinson's disease (PD). The G2019S \nvariant is the most common, which results in abnormally high kinase..."", 'thumbnail': 'https://serpapi.com/searches/6723e60eb9ab86664a9fd180/images/2e9c49b6fdf52818722f830436cd6fe0290542da3ce603ca9751595c17e46e66.png', 'sentiment': 'negative', 'sentiment_prob': 0.8432062864303589}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.00807/full', 'title': 'Pharmacodynamic Biomarkers for Emerging LRRK2 Therapeutics', 'source': 'Frontiers', 'date': 'Aug 6, 2020', 'snippet': ""Genetic studies have identified variants in the LRRK2 gene as important \ncomponents of Parkinson's disease (PD) pathobiology."", 'thumbnail': 'https://serpapi.com/searches/6723e60eb9ab86664a9fd180/images/2e9c49b6fdf52818ee1907d32c3358f3abde99acdde6cace1096eadb6f0bf38e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9109451770782471}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT01782963,"{'position': 1, 'link': 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National Institute of Allergy and Infectious Diseases \n(NIAID) are conducting a clinical trial designed to help...', 'thumbnail': 'https://serpapi.com/searches/6723e400671f3f492b26ed15/images/1d1545461ffb1d4d0e46870a0c63f9040c4df0f5da1a7ed613bf9d5629201346.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8957304358482361}",,,,,,,,,,['neutral'],neutral,1 NCT02252211,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-022-04984-6', 'title': 'Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1', 'source': 'Nature', 'date': 'Jun 6, 2022', 'snippet': 'The cell signaling factors EGFR, EphA2, and Ephexin1 are associated with \nlung and colorectal cancer and play an important role in tumorigenesis.', 'thumbnail': 'https://serpapi.com/searches/6723e41c93584cf63bb0290e/images/9065ccd4b32e25b13ca8fb7ab5ee245b516b7714a34557117635a3fcb4f8a69f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8681862950325012}",,,,,,,,,,['neutral'],neutral,1 NCT03995888,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/62/12/1719', 'title': 'Detection Efficacy of 18F‐rhPSMA‐7.3 PET/CT and Impact on Management in Patients with Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy and Before Potential Salvage Treatment', 'source': 'Journal of Nuclear Medicine', 'date': 'Dec 1, 2021', 'snippet': '18 F-rhPSMA-7.3 PET offered high detection efficacy in patients with \nbiochemical recurrence after radical prostatectomy and before potential \nsalvage therapy.', 'thumbnail': 'https://serpapi.com/searches/6723e5ea3b3c321342fab432/images/0d4c3d204ead60e463dcb338341f7443dddc26a7f349b96eeaccf34bf9056b21.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7946215271949768}",,,,,,,,,,['neutral'],neutral,1 NCT04184063,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2021.720220/full', 'title': 'Novel Therapies for Parkinsonian Syndromes–Recent Progress and Future Perspectives', 'source': 'Frontiers', 'date': 'Jun 26, 2024', 'snippet': ""1Students' Scientific Association of the Department of Neurology, Medical \nUniversity of Warsaw, Warsaw, Poland; 2Department of Neurology, Medical \nUniversity..."", 'thumbnail': 'https://serpapi.com/searches/6723e5f8c1c8ddff1711d2ff/images/9cca4754d112e6a0da5a5819421e047010b14c88b842314ac4dfdcf41e7e6fee.png', 'sentiment': 'neutral', 'sentiment_prob': 0.93094402551651}",,,,,,,,,,['neutral'],neutral,1 NCT02564055,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/gsk-sells-psoriasis-dermatitis-candidate-tapinarof-to-dermavant/', 'title': 'GSK Sells Psoriasis/Dermatitis Candidate Tapinarof to Dermavant', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Jul 12, 2018', 'snippet': 'Dermavant agreed to pay up to £250M ($330M) for mostly-global rights to the \ntherapeutic aryl hydrocarbon receptor modulating agent (TAMA),...', 'thumbnail': 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'https://www.nature.com/articles/nrd3687', 'title': 'Steps towards an HCV vaccine', 'source': 'Nature', 'date': 'Feb 17, 2012', 'snippet': 'Results from a clinical study (ClinicalTrials.gov identifier: NCT01070407) \nof an investigational adenovirus-based vaccine against hepatitis...', 'thumbnail': 'https://serpapi.com/searches/6723e4d4caddc3538c855966/images/ae70670cc3a79dc3185fdd6551113247f54276bb5719c3048bcda2cd6a3b16e8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9137281179428101}",,,,,,,,,,['neutral'],neutral,1 NCT02224157,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1715275', 'title': 'As-Needed Budesonide–Formoterol versus Maintenance Budesonide in Mild Asthma', 'source': 'The New England Journal of Medicine', 'date': 'May 16, 2018', 'snippet': 'Patients with mild asthma often rely on inhaled short-acting β2-agonists \nfor symptom relief and have poor adherence to maintenance therapy.', 'thumbnail': 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effectiveness, including in almost 50% of \nponatinib pretreated patients, and confirm its risk-benefit profile."", 'thumbnail': 'https://serpapi.com/searches/6723e6b0993688064fac049b/images/27e2e4718579870e81cc4ea26f2ecce83fb562d1ebdad88019bfa7c233ca056a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6183647513389587}",,,,,,,,,,['neutral'],neutral,1 NCT00931632,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/inhaled-nitric-oxide-and-survival-in-preterm-infants-without-bronchopulmonary-dysplasia/', 'title': 'Inhaled Nitric Oxide and Survival in Preterm Infants Without Bronchopulmonary Dysplasia', 'source': 'Pulmonology Advisor', 'date': 'Oct 18, 2017', 'snippet': 'The use of inhaled nitric oxide in premature infants without \nbronchopulmonary dysplasia (BPD) appears to be safe, but it does not \nimprove survival rates.', 'thumbnail': 'https://serpapi.com/searches/6723e6c58de63cf49777b1e3/images/ae7b2e7e8f04a01dc6588c0294160f664cf9ae927aa8da3bc4777b7fb196aec0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7672607898712158}",,,,,,,,,,['neutral'],neutral,1 NCT04121221,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/03/11/fda-declines-us-approval-ga-depot-relapsing-ms-treatment/', 'title': 'FDA declines to approve GA Depot as treatment for relapsing MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 11, 2024', 'snippet': 'The U.S. Food and Drug Administration (FDA) has decided not to approve an \napplication seeking clearance of GA Depot — a long-acting formulation...', 'thumbnail': 'https://serpapi.com/searches/6723e6cfdc969f85ff181446/images/c093819cf27482011a412654b48b99c0dd9db49e4bfb4ae65d665097ac43e813.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5317093729972839}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/long-acting-glatiramer-acetate-depot-under-review-for-relapsing-ms/', 'title': 'Long-Acting Glatiramer Acetate Depot Under Review for Relapsing MS', 'source': 'Medical Professionals Reference', 'date': 'Aug 7, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted for review the New Drug \nApplication for glatiramer acetate (GA) Depot 40mg for the treatment of \nrelapsing...', 'thumbnail': 'https://serpapi.com/searches/6723e6cfdc969f85ff181446/images/c093819cf2748201bb0c4646deac16e972ddc82a9d61f46cfe46649dce339af5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8663263916969299}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/fda-decision-ga-depot-relapsing-ms-expected-march-2024/', 'title': 'FDA decision on GA Depot for relapsing MS expected March 2024 –...', 'source': 'Multiple Sclerosis News Today', 'date': 'Aug 8, 2023', 'snippet': ""The U.S. Food and Drug Administration (FDA) has agreed to review Viatris \nand Mapi Pharma's application seeking approval of GA Depot for the..."", 'thumbnail': 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Learn about uses, side effects, and clinical testing.', 'thumbnail': 'https://serpapi.com/searches/6723e6cfdc969f85ff181446/images/c093819cf27482016343345f8f494ed78fa9af79528bfb843ddaffb0c94e8995.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9161229729652405}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT05007951,"{'position': 1, 'link': 'https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00317-6/fulltext', 'title': 'Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial - eClinicalMedicine', 'source': 'The Lancet', 'date': 'Sep 7, 2023', 'snippet': 'GBP510 vaccine contains self-assembling, recombinant nanoparticles \ndisplaying SARS-CoV-2 spike receptor-binding domains.', 'thumbnail': 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'Myasthenia Gravis News', 'date': 'Jan 25, 2024', 'snippet': 'Rystiggo (rozanolixizumab-noli) is an injection therapy approved for adults \nwith generalized myasthenia gravis (gMG) who have antibodies against the...', 'thumbnail': 'https://serpapi.com/searches/6723e7015f97789cdc77af8d/images/1f70d30e97dd2924603e5643c7c637347a9a679ef1c16a86695190b667cd4f02.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8568547368049622}",,,,,,,,,,['neutral'],neutral,1 NCT03099304,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/jdv.20236', 'title': 'Journal of the European Academy of Dermatology and Venereology', 'source': 'Wiley Online Library', 'date': 'Jul 16, 2024', 'snippet': 'Ruxolitinib cream produced clinically meaningful repigmentation of all body \nareas, including hands and feet.', 'thumbnail': 'https://serpapi.com/searches/6723e71e0664c95f199942e6/images/42c909639e2fb24a391b652e1d0e0094b82c02f4936a380bd7df9468342b6515.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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progression in SPMS', 'source': 'Multiple Sclerosis News Today', 'date': '1 month ago', 'snippet': 'Confirmed six-month disability progression rates over 4 years were similar \nin patients given the oral statin or a placebo in Phase 3 trial.', 'thumbnail': 'https://serpapi.com/searches/6723e98ce45f33ae4e644522/images/8d2c636aad025b7552c8c4a4f0e5e7acbcbbf79c53e28763486c61a25a4cf7f8.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7357134819030762}",,,,,,,,,,['negative'],negative,0 NCT02961257,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/cabazitaxel-at-lowered-dose-increased-frequency-reduces-neutropenic-complications-in-older-patients-with-mcrpc', 'title': 'Cabazitaxel at Lowered Dose, Increased Frequency Reduces Neutropenic Complications in Older Patients With mCRPC', 'source': 'Cancer Network', 'date': 'Oct 25, 2022', 'snippet': 'Results of the randomized phase 3 CABASTY trial (NCT02961257), which were \nrecently presented at the 2022 European Society for Medical...', 'thumbnail': 'https://serpapi.com/searches/6723e74f0f1a336e05f582a0/images/67984c641d43640c9e718e38e3c121d32cc6b3fbed84fe8e3c2420437676ce31.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8543075323104858}",,,,,,,,,,['neutral'],neutral,1 NCT02507219,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-04875-y', 'title': 'Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial', 'source': 'Nature', 'date': '١٧\u200f/٠١\u200f/٢٠٢٢', 'snippet': 'This double-blind, randomized, within-subjects design evaluated whether \nacute administration of an anti-inflammatory drug modulates...', 'thumbnail': 'https://serpapi.com/searches/6723e773db3ac9f318304d31/images/b981b56a37a2844fba57fe07e94ad15076fc178f2484411929bd210253e1565a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.836776614189148}",,,,,,,,,,['neutral'],neutral,1 NCT02741323,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-clinical-trial-track-outcomes-kidney-transplantation-hiv-positive-donors-hiv-positive-recipients', 'title': 'NIH clinical trial to track outcomes of kidney transplantation from HIV-positive donors to HIV-positive recipients', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'May 7, 2018', 'snippet': 'The first large-scale clinical trial to study kidney transplantations \nbetween people with HIV has begun at clinical centers across the United \nStates.', 'thumbnail': 'https://serpapi.com/searches/6723e8eafd3b5abd335a573d/images/1f64e7b096d8c53bd11c97fb9989f354fd673e0995118871e0c7d597caa1160e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9262402653694153}","{'position': 2, 'link': 'https://news.emory.edu/stories/2016/09/pearson_hiv_positive_kidney_transplant_drug_trial/index.html', 'title': 'Emory will study use of FDA-approved drug in HIV positive patients receiving kidney transplants', 'source': 'Emory University', 'date': 'Sep 1, 2016', 'snippet': 'Thomas Pearson, MD, is the principal investigator of an Emory clinical \ntrial testing a FDA-approved drug in HIV positive patients receiving a \nkidney transplant.', 'thumbnail': 'https://serpapi.com/searches/6723e8eafd3b5abd335a573d/images/1f64e7b096d8c53bbf9cce90cf3bb6b604512e0be7ed572bfbc55c74e41222ed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9237295389175415}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02030860,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2022.1020888/full', 'title': 'Culprits of PDAC resistance to gemcitabine and immune checkpoint inhibitor: Tumour microenvironment components', 'source': 'Frontiers', 'date': 'Oct 9, 2022', 'snippet': 'In our review, we shed light on how crosstalk of complex environmental \ncomponents modulates PDAC drug resistance, and we summarize related \nclinical trials.', 'thumbnail': 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'Benralizumab for patients with mild to moderate, persistent asthma (BISE): a randomised, double-blind, placebo-controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'May 22, 2017', 'snippet': 'Benralizumab is a humanised, anti-interleukin 5 receptor α monoclonal \nantibody that directly and rapidly depletes eosinophils, reduces asthma \nexacerbations,...', 'thumbnail': 'https://serpapi.com/searches/6723e917e1c27684e5a655ad/images/293b580063bd251ae1fd00b2e9ede06b8268a10d62ec86f6084406b6958de6f3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8085067868232727}",,,,,,,,,,['neutral'],neutral,1 NCT03758924,"{'position': 1, 'link': 'https://rettsyndromenews.com/news/anavex-2-73-shows-promise-rett-children-but-misses-trial-goal/', 'title': 'Anavex 2-73 shows promise for Rett children but misses trial goal', 'source': 'Rett Syndrome News', 'date': 'Jan 2, 2024', 'snippet': 'Treatment with Anavex 2-73 led to improvements in behavior for Rett \nsyndrome children, but a Phase 2/3 clinical trial failed to meet its...', 'thumbnail': 'https://serpapi.com/searches/6723e9194a4a1dafcdcf2e50/images/dd7d89e203c8bdf70cb0576c84a2b99edc196f6dbf5d46eab259e7dd87056f3b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5686342120170593}","{'position': 2, 'link': 'https://rettsyndromenews.com/news/trial-results-anavex-2-73-rett-syndrome-very-promising/', 'title': 'Latest Trial Results of Anavex 2-73 ‘Very Promising’', 'source': 'Rett Syndrome News', 'date': 'Jun 23, 2021', 'snippet': 'Clinical improvements with Anavex 2-73, by Anavex Life Sciences, correlated \nwith activation of the SIGMAR1 gene in a Phase 2 clinical trial.', 'thumbnail': 'https://serpapi.com/searches/6723e9194a4a1dafcdcf2e50/images/dd7d89e203c8bdf75f4800e02515e3d18bc4d2596151810f26b8b2f2e45ccc66.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8713425993919373}","{'position': 3, 'link': 'https://www.nature.com/articles/s41598-021-94079-7', 'title': 'Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy | Scientific Reports', 'source': 'Nature', 'date': 'Aug 25, 2021', 'snippet': 'Fragile X syndrome (FXS), a disorder of synaptic development and function, \nis the most prevalent genetic form of intellectual disability and...', 'thumbnail': 'https://serpapi.com/searches/6723e9194a4a1dafcdcf2e50/images/dd7d89e203c8bdf7a14f56639574d5740da1f516ec9a81e4a1d6122c9e4c5fec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7516513466835022}","{'position': 4, 'link': 'https://rettsyndromenews.com/news/phase-2-extension-trial-shows-sustained-benefits-anavex-2-73/', 'title': 'Phase 2 extension trial shows sustained benefits of Anavex 2-73 –...', 'source': 'Rett Syndrome News', 'date': 'Jul 5, 2023', 'snippet': 'The benefits of Anavex 2-73 observed in a Phase 2 clinical trial were \nsustained in an open-label extension phase.', 'thumbnail': 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'https://liverdiseasenews.com/news/tirzepatide-weight-treats-fatty-liver-disease-phase-2-trial/', 'title': 'Tirzepatide for weight loss treats fatty liver disease in Phase 2 trial', 'source': 'Liver Disease News', 'date': 'Feb 12, 2024', 'snippet': 'Weekly injections of tirzepatide, an approved obesity and diabetes \ntreatment, showed promise in people with nonalcoholic steatohepatitis \n(NASH).', 'thumbnail': 'https://serpapi.com/searches/6723e9199e5bd54156a5ed31/images/bad94597ce305927e72d0fe4b88111bd42cecd201332c616c910969d87e68134.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6470713019371033}","{'position': 3, 'link': 'https://www.thelancet.com/journals/landia/article/PIIS2213-8587(22)00074-2/fulltext', 'title': 'Tirzepatide adds hepatoprotection to its armoury', 'source': 'The Lancet', 'date': 'Apr 22, 2022', 'snippet': 'In The Lancet Diabetes & Endocrinology, Amalia Gastaldelli and colleagues. \n1. Gastaldelli, A ∙ Cusi, K ∙ Fernández Landó, L ∙ et al.', 'thumbnail': 'https://serpapi.com/searches/6723e9199e5bd54156a5ed31/images/bad94597ce3059271dca105d26ef0d26093dccb3b0ff7179610524c21ce71d45.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6948352456092834}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02573259,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20240530243565/en/Onc.AI-to-Present-Collaboration-Results-Demonstrating-Immunotherapy-Response-Prediction-Using-a-Radiomic-Signature-in-Late-Stage-Lung-Cancer', 'title': 'Onc.AI to Present Collaboration Results Demonstrating Immunotherapy Response Prediction Using a Radiomic Signature in Late-Stage Lung Cancer', 'source': 'Business Wire', 'date': 'May 30, 2024', 'snippet': 'Onc.AI, a digital health company developing a novel oncology clinical \nmanagement solution, today announced that new data will be presented...', 'thumbnail': 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eye drops found safe and effective in diabetic retinopathy and diabetic macular edema in New trial', 'source': 'Medical Dialogues', 'date': 'Mar 14, 2024', 'snippet': 'New eye drop treatment has been found to be safe and tolerable with 100% \nparticipants completing the study for diabetic retinopathy and...', 'thumbnail': 'https://serpapi.com/searches/6723e8bb1b4e34015b421f08/images/1b7b8064432ce33ee51361123377e5038acd650e337179b6107facbc0d566b9b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8344739675521851}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02962908,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/abs/pii/S014181302400062X', 'title': 'Self-adjuvant multiepitope nanovaccine based on ferritin induced long-lasting and effective mucosal immunity against H3N2 and H1N1 viruses in mice', 'source': 'ScienceDirect.com', 'date': 'Jan 7, 2024', 'snippet': 'The prokaryotically expressed multiepitope nanovaccine elicits long-lasting \nmucosal immunity, 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NCT02256436,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1613683', 'title': 'Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma', 'source': 'The New England Journal of Medicine', 'date': 'Feb 17, 2017', 'snippet': 'In this open-label, international, phase 3 trial, we randomly assigned 542 \npatients with advanced urothelial cancer that recurred or...', 'thumbnail': 'https://serpapi.com/searches/6723e7ba2b5fa7541e6e5082/images/155da3d5a683bcf88540367d90c76d1b00540107487f8e744c44231489521842.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8931952714920044}",,,,,,,,,,['neutral'],neutral,1 NCT04580407,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/obizur-effective-acquired-hemophilia-a-treatment-study/', 'title': 'Obizur effective as acquired hemophilia A treatment: Study', 'source': 'Hemophilia News Today', 'date': '1 month ago', 'snippet': 'Obizur was effective and safe in treating severe bleeding episodes in \nJapanese patients with acquired hemophilia A, per a study.', 'thumbnail': 'https://serpapi.com/searches/6723e80fe30abce600f7676e/images/9c640409ccb3d78cae946bb0a5bef66e1ca6de2d213ea3c353508f4531427d91.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5109249949455261}",,,,,,,,,,['neutral'],neutral,1 NCT01894958,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/decisional-intervention-may-be-beneficial-for-parents-of-fxs-chidren/', 'title': 'Information, Support May Persuade Parents of FXS Children to Join Trials', 'source': 'Fragile X News Today', 'date': 'Feb 19, 2019', 'snippet': 'Parents of children with intellectual disability, in particular those \naffected by fragile X syndrome, may benefit from more information and \ndedicated support.', 'thumbnail': 'https://serpapi.com/searches/6723e8330c08f2dbea83031d/images/90e7e8c2f18376ac68f8f854f00c4a34d0f48b652a74e5ec2d1953e5c792115b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6160650849342346}",,,,,,,,,,['neutral'],neutral,1 NCT02782741,"{'position': 1, 'link': 'https://pompediseasenews.com/news/nexviadyme-next-generation-ert-now-available-uk-nhs/', 'title': 'Nexviadyme, next-generation ERT for Pompe, is now available in UK...', 'source': 'Pompe Disease News', 'date': 'Feb 9, 2023', 'snippet': ""Nexviadyme (avalglucosidase alfa), a next-generation enzyme replacement \ntherapy for Pompe disease, will be available through the U.K.'s NHS."", 'thumbnail': 'https://serpapi.com/searches/6723e9a05416d8fd44a56d32/images/1adb8b48e5f033108fc6981ff5548fb9d665754b13d0cf7ce9139988207a9f85.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7312231659889221}","{'position': 2, 'link': 'https://pompediseasenews.com/news/fda-approves-nexviazyme-next-generation-enzyme-replacement-therapy-late-onset-pompe-disease/', 'title': 'Next-generation ERT Nexviazyme Approved by FDA for Late-onset Pompe', 'source': 'Pompe Disease News', 'date': 'Aug 9, 2021', 'snippet': 'The US Food and Drug Administration (FDA) has approved Nexviazyme \n(avalglucosidase alfa), a next-generation enzyme replacement therapy for \nlate-onset Pompe...', 'thumbnail': 'https://serpapi.com/searches/6723e9a05416d8fd44a56d32/images/1adb8b48e5f033106ff60ff0a8d01d87649b3a58f7ecf81a15d13b7754e6266a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.798860490322113}","{'position': 3, 'link': 'https://pompediseasenews.com/news/eu-approval-urged-new-pompe-ert-avalglucosidase-alfa/', 'title': 'EU Approval Urged for New Sanofi ERT Avalglucosidase Alfa', 'source': 'Pompe Disease News', 'date': 'Jul 27, 2021', 'snippet': 'A European Medicines Agency committee recommended that avalglucosidase alfa \nbe approved as an enzyme replacement therapy for Pompe disease.', 'thumbnail': 'https://serpapi.com/searches/6723e9a05416d8fd44a56d32/images/1adb8b48e5f033104882d1c811c240de5b24cfe374a88aa8814d3bdb4cf581c5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8937884569168091}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03951623,"{'position': 1, 'link': 'https://www.onclive.com/view/nmpa-accepts-and-grants-priority-review-to-nda-for-sovleplenib-in-primary-immune-thrombocytopenia', 'title': 'NMPA Accepts and Grants Priority Review to NDA for Sovleplenib in Primary Immune Thrombocytopenia', 'source': 'OncLive', 'date': 'Jan 11, 2024', 'snippet': 'The China National Medical Products Administration has accepted the NDA \nseeking approval of sovleplenib in patients with primary immune...', 'thumbnail': 'https://serpapi.com/searches/6723eb02c024d1931bae8118/images/7d4d7dd5d02be36c2874f2755a6c47f7fde25a588d9b0cceb424fe04c95e84c8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8363224864006042}",,,,,,,,,,['neutral'],neutral,1 NCT01810393,"{'position': 1, 'link': 'https://www.onclive.com/view/subcutaneous-trastuzumab-proves-safe-and-tolerable-in-her2-metastatic-breast-cancer', 'title': 'Subcutaneous Trastuzumab Proves Safe and Tolerable in HER2+ Metastatic Breast Cancer', 'source': 'OncLive', 'date': 'Aug 28, 2023', 'snippet': 'The safety profile of subcutaneous trastuzumab (Herceptin) was consistent \nwith the known profile of intravenous administration of the agent and there \nwere no...', 'thumbnail': 'https://serpapi.com/searches/6723eb04c821271837d7b487/images/08de0b266d16ff872a5324897164fca5a2ac523a4795d1b3e6551e007ffa508c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5896600484848022}",,,,,,,,,,['neutral'],neutral,1 NCT05059301,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-023-00729-4', 'title': 'Immunogenicity of an AS01-adjuvanted respiratory syncytial virus prefusion F (RSVPreF3) vaccine in animal models', 'source': 'Nature', 'date': 'Sep 29, 2023', 'snippet': 'Respiratory syncytial virus (RSV) causes a high disease burden in older \nadults. 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first-of-its-kind fixed dose study, once weekly insulin efsitora alfa leads to A1C reduction similar to daily insulin', 'source': 'PR Newswire', 'date': 'Sep 5, 2024', 'snippet': 'PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced positive \ntopline results from the QWINT-1 and QWINT-3 phase 3 clinical...', 'thumbnail': 'https://serpapi.com/searches/6723e9f41a5b542101c410fc/images/a6693ae3d43e288d7a6e5e593d68d9b6f6c6dbfdeb562ad3b96bf55d1329fdd1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8551015853881836}","{'position': 2, 'link': 'https://www.endocrinologyadvisor.com/news/insulin-efsitora-alfa/', 'title': 'Insulin Efsitora Alfa Demonstrates Non-Inferior Glycemic Control in T2D', 'source': 'Endocrinology Advisor', 'date': '1 month ago', 'snippet': 'Treatment with once-weekly insulin efsitora alfa, compared with daily basal \ninsulins, effects non-inferior glycemic control and a similar safety \nprofile.', 'thumbnail': 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'https://www.psychiatrist.com/pcc/subanalysis-of-subjective-cognitive-measures-from-a-phase-2-double-blind-randomized-trial-of-rel-1017-in-patients-with-major-depressive-disorder/', 'title': 'Subanalysis of Subjective Cognitive Measures From a Phase 2, Double-Blind, Randomized Trial of REL-1017 in Patients With Major Depressive Disorder', 'source': 'Psychiatrist.com', 'date': 'Feb 14, 2023', 'snippet': 'In a Phase 2a clinical trial, REL-1017 improved subjective measures of \ncognitive impairment, in addition to improving total MADRS and SDQ scores.', 'thumbnail': 'https://serpapi.com/searches/6723ea38fc40bf31d0398dac/images/bf60e2a8cc24f1e339a29ecf1929f5f110e631c9188882bef014573fd8fac44e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.776265025138855}",,,,,,,,,,['neutral'],neutral,1 NCT00972179,"{'position': 1, 'link': 'https://www.dermatologyadvisor.com/news/two-phase-1-studies-evaluate-safety-of-tezepelumab-for-atopic-dermatitis/', 'title': 'Two Phase 1 Studies Evaluate Safety of Tezepelumab for Atopic Dermatitis', 'source': 'Dermatology Advisor', 'date': 'Mar 22, 2019', 'snippet': 'Two phase 1 studies assessed the safety, tolerability, and pharmacokinetics \nof tezepelumab with evidence of efficacy in asthma and potential...', 'thumbnail': 'https://serpapi.com/searches/6723ea41c82127187f68d9d7/images/9d037f00a876e142c73ec899b330f112ed2f4411b219831c859487c388dd41f7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8194459676742554}",,,,,,,,,,['neutral'],neutral,1 NCT04728360,"{'position': 1, 'link': 'https://www.biospace.com/bio-thera-solutions-announces-positive-results-from-phase-3-study-of-bat2206-a-proposed-biosimilar-referencing-stelara', 'title': 'Bio-Thera Solutions Announces Positive Results from Phase 3 Study of BAT2206, a Proposed Biosimilar Referencing Stelara', 'source': 'BioSpace', 'date': 'Nov 29, 2023', 'snippet': 'Bio-Thera Solutions, Ltd., a commercial-stage biopharmaceutical company \ndeveloping a pipeline of biosimilars and innovative assets,...', 'thumbnail': 'https://serpapi.com/searches/6723ea6facf7f88b430d6f81/images/85b76f9261ca59bfd6de2525845cbc0d10e4cbee5079a606538c16165005aed7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5072025060653687}",,,,,,,,,,['neutral'],neutral,1 NCT01837251,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2020/07/30/liposomal-doxorubicin-based-regimen-improves-outcomes-in-platinum-sensitive-recurrent-ovarian-cancer/', 'title': 'In Platinum-sensitive OC, Liposomal Doxorubicin Found to Extend Survival', 'source': 'Ovarian Cancer News Today', 'date': 'Jul 30, 2020', 'snippet': 'A combination of bevacizumab, carboplatin, and liposomal doxorubicin may \nimprove the outcomes of platinum-sensitive ovarian cancer patients,...', 'thumbnail': 'https://serpapi.com/searches/6723eac00f2a2cff3865edce/images/a8cf070273cf414a1bac74aedfe1ac0e780d4d0905b3a745668ef69dcde83766.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5243479609489441}",,,,,,,,,,['neutral'],neutral,1 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multiple \norgan damages which may cause mortality and is usually accompanied...', 'thumbnail': 'https://serpapi.com/searches/6723eb3263a844cecdffd725/images/36505c50a74ecf163dba8aacb4904c3b0c2ff5a472a4cc5c8308fec3d220ac5a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5149408578872681}",,,,,,,,,,['neutral'],neutral,1 NCT05668754,"{'position': 1, 'link': 'https://www.stocktitan.net/news/ZVRA/zevra-therapeutics-to-present-top-line-data-from-the-phase-2-rm8qea7dn9fn.html', 'title': 'Zevra Therapeutics to Present Top-Line Data from the Phase 2 Clinical Trial of KP1077 for Idiopathic Hypersomnia at Sleep Europe 2024', 'source': 'Stock Titan', 'date': '1 month ago', 'snippet': ""Zevra's KP1077 shows promise for idiopathic hypersomnia in Phase 2 trial. \nLearn about the clinically meaningful benefits and future Phase 3..."", 'thumbnail': 'https://serpapi.com/searches/6723eb36b9458db6b3587b85/images/904c74c0764eaaaa78388e7f87592fd706de2bb786232a736f0525509ec753d7.jpeg', 'sentiment': 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5, 2024', 'snippet': 'The US Food and Drug Administration (FDA) has approved Bkemv \n(eculizumab-aeeb), the first interchangeable biosimilar to Soliris \n(eculizumab), to treat people...', 'thumbnail': 'https://serpapi.com/searches/6723eb3d7ef9fa2958e91daf/images/2fbaeefaa1b7375e82bc7a02781913d3d26e51ff7805f8a5d3e99afa143304cc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7452104091644287}",,,,,,,,,,['neutral'],neutral,1 NCT00574288,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/characteristics-myeloma-disease-may-impact-exposure-darzalex-study-reports/', 'title': 'Type of Multiple Myeloma May Affect Responses to Darzalex, Study Finds', 'source': 'Myeloma Research News', 'date': 'Oct 20, 2017', 'snippet': 'A new study reports that the specific type of multiple myeloma (MM) may \naffect how long the drug Darzalex (daratumumab) remains in circulation.', 'thumbnail': 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'link': 'https://www.nature.com/articles/s41698-022-00341-0', 'title': 'BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study | npj Precision Oncology', 'source': 'Nature', 'date': 'Feb 18, 2023', 'snippet': 'We performed a pooled analysis of four phase one studies evaluating the \nsafety and efficacy of vemurafenib monotherapy and vemurafenib combined \nwith targeted...', 'thumbnail': 'https://serpapi.com/searches/6723ec9fc024d1935d72d9c8/images/e32e8f23b37e52272032042f269c20bece3039a83aca83ba9450ee9bed26dc6d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9065907597541809}",,,,,,,,,,['neutral'],neutral,1 NCT01030861,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1902226', 'title': 'An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Jun 9, 2019', 'snippet': 'We 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'date': 'Nov 16, 2019', 'snippet': 'Experimental and clinical evidence supports the role of inflammation in \natherosclerosis and its complications. 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Administration (FDA) has approved Keytruda \n(pembrolizumab) as a treatment for people with recurrent or metastatic \ncutaneous squamous cell...', 'thumbnail': 'https://serpapi.com/searches/6723ebf193bb5713f02df4a8/images/4f449ea20fb15f88004f08430e04fcbb5e18aa00b2b7a1c3f5091d04591ad2ef.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7842790484428406}",,,,,,,,,,['neutral'],neutral,1 NCT04209634,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-greenlights-veopoz-the-first-treatment-for-chaple-disease/', 'title': 'FDA Greenlights Veopoz, the First Treatment for CHAPLE Disease', 'source': 'Medical Professionals Reference', 'date': 'Aug 21, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Veopoz™ \n(pozelimab-bbfg) for the treatment of adult and pediatric patients 1 year \nof age...', 'thumbnail': 'https://serpapi.com/searches/6723ec16d78a98c21a5e27f0/images/097adef8310ff1aae38ee1f6602128b48469d21c96a37b4e611a08fe3c03d6b7.jpeg', 'sentiment': 'neutral', 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'source': 'Melanoma News Today', 'date': 'Apr 25, 2017', 'snippet': ""Read about the approval for the third cohort of a Phase 1 melanoma trial \nassessing the combination of Prima Biomed's IMP321 and Keytruda."", 'thumbnail': 'https://serpapi.com/searches/6723ed874791c44b726c20ff/images/968a6b5bff41a4942f3f5393b2b3ab7d285bbf2209ba4b10b7a39c55158ed7f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8649411201477051}",,,,,,,,,,['neutral'],neutral,1 NCT04003389,"{'position': 1, 'link': 'https://www.empr.com/home/news/veozah-approved-for-moderate-to-severe-vasomotor-symptoms-due-to-menopause/', 'title': 'Veozah Approved for Moderate to Severe Vasomotor Symptoms Due to Menopause', 'source': 'Medical Professionals Reference', 'date': 'May 15, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Veozah™ (fezolinetant) \nfor the treatment of moderate to severe vasomotor symptoms due to...', 'thumbnail': 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'thumbnail': 'https://serpapi.com/searches/6723ee02a88278e9fc574d1d/images/68f1caa809c3d835ae22fdd05571031a33b9b9f92795610a897d887d0b7e796c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7561503052711487}",,,,,,,,,,['neutral'],neutral,1 NCT03440814,"{'position': 1, 'link': 'https://praderwillinews.com/news/children-switch-dccr-placebo-worsening-hyperphagia-trial/', 'title': 'PWS children who switch from DCCR see worsening hyperphagia: Trial', 'source': 'Prader-Willi Syndrome News', 'date': 'Oct 5, 2023', 'snippet': 'PWS patients who switched from daily treatment with DCCR (diazoxide choline \nextended-release tablets) to a placebo experienced worsening excessive \nhunger, or...', 'thumbnail': 'https://serpapi.com/searches/6723ee1cfab27313b26fb84b/images/cc4eecc221972a3159308a9003ac8f9c1ae86ce75437378450dc63d1af755f36.png', 'sentiment': 'neutral', 'sentiment_prob': 0.565572202205658}","{'position': 2, 'link': 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Disposition of patients in ACTIVExtend (extension trial of...', 'source': 'ResearchGate', 'date': 'Mar 15, 2020', 'snippet': 'To assess the efficacy and safety of 18 months of subcutaneous \nabaloparatide (ABL-SC) or placebo (PBO) followed by 6 months of alendronate \n(ALN)', 'thumbnail': 'https://serpapi.com/searches/6723ef2fb2ebaec178350856/images/725c90dc74d48b1ef0cebfb2af4855f8f9c62af0c15561294acf680f22732eaa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8821626305580139}",,,,,,,,,,['neutral'],neutral,1 NCT00004074,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.01544/full', 'title': 'Interplay between Natural Killer Cells and Anti-HER2 Antibodies: Perspectives for Breast Cancer Immunotherapy', 'source': 'Frontiers', 'date': 'Feb 10, 2024', 'snippet': '1Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain; 2Department \nof Oncology, Hospital del Mar-CIBERONC, Barcelona, Spain...', 'thumbnail': 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17, 2023', 'snippet': ""Illumina's Q2 revenue rose nearly 1% from $1.162 billion to $1.172 billion, \nahead of company guidance and analyst estimates."", 'thumbnail': 'https://serpapi.com/searches/6723f12d207c88686f8a26ea/images/a636e559b87f6a2e624e14c49d54b8730161d2529b80357edb6b67fd7ca75e87.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6198692321777344}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT04932434,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/top-10-parkinsons-news-stories-bionews-published-2023/', 'title': 'Top 10 Parkinson’s stories of 2023', 'source': ""Parkinson's News Today"", 'date': 'Jan 2, 2024', 'snippet': ""Here are the 10 most widely read stories published in 2023 by Parkinson's \nNews Today, which reports on disease discoveries and developments."", 'thumbnail': 'https://serpapi.com/searches/6723f14faab36de63561a60e/images/ffffc5183f49259b21be7a54482a059a4b600fb01aef50e4e0adb083714c69fa.png', 'sentiment': 'neutral', 'sentiment_prob': 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'Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib', 'source': 'The New England Journal of Medicine', 'date': 'Nov 16, 2014', 'snippet': 'The BRAF inhibitors vemurafenib and dabrafenib have shown efficacy as \nmonotherapies in patients with previously untreated metastatic...', 'thumbnail': 'https://serpapi.com/searches/6723f2282bab90365063b331/images/6d499a3dde8a004019f125cd1f98315093e904e39ba1b1b4943ffc6c1fd0f5ff.png', 'sentiment': 'positive', 'sentiment_prob': 0.5727618932723999}",,,,,,,,,,['positive'],positive,1 NCT05172934,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.027', 'title': 'Abstract 027: Adjunctive Intra‐Arterial Tenecteplase Following Mechanical Thrombectomy. (ALLY) Pilot Trial', 'source': 'American Heart Association Journals', 'date': 'Nov 10, 2023', 'snippet': 'This study evaluated the safety and efficacy of intraarterial Tenecteplase \n(IA TNK) as an adjunctive therapy to mechanical thrombectomy in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/6723f23858e433cfdc869519/images/94a4e92e0294dbffa82c54625d6bd1ed4d5622ae550dd9e93a7f7a445b19cd7c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8906093835830688}",,,,,,,,,,['neutral'],neutral,1 NCT02185417,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2212270', 'title': 'Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events', 'source': 'The New England Journal of Medicine', 'date': 'Dec 14, 2022', 'snippet': 'Whether chlorthalidone is superior to hydrochlorothiazide for preventing \nmajor adverse cardiovascular events in patients with hypertension is \nunclear.', 'thumbnail': 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with Finerenone in Kidney Disease and Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Aug 28, 2021', 'snippet': 'Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, \nhas favorable effects on cardiorenal outcomes in patients with \npredominantly stage...', 'thumbnail': 'https://serpapi.com/searches/6723f1997ca6b38026f05303/images/ae385cf0e9d82a6efcdf76f32d7483da4c7c5a179d830a0aef54579c3c70a546.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8563430309295654}","{'position': 2, 'link': 'https://www.thecardiologyadvisor.com/news/finerenone-cardiovascular-events-chronic-kidney-disease-ckd-type-2-diabetes-t2d/', 'title': 'Edoxaban Non-Inferior to Vitamin K Antagonists in Atrial Fibrillation Post-TAVR', 'source': 'The Cardiology Advisor', 'date': 'Dec 28, 2021', 'snippet': 'Patients with type 2 diabetes and chronic kidney disease who received \nfinerenone had a lower heart failure hospitalization rate,...', 'thumbnail': 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hormone \nreplacement..."", 'thumbnail': 'https://serpapi.com/searches/6723f1c89e5bd5411c0a6dcb/images/c40231f6d192e7f126aadee931c1b25ca30fbcfc7d1ceb4041dc1e4d7e3096c7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.914821445941925}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02363855,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/darolutamide-yields-positive-safety-data-in-mcrpc', 'title': 'Darolutamide Yields Positive Safety Data in mCRPC', 'source': 'Cancer Network', 'date': 'Feb 18, 2022', 'snippet': 'Patients with metastatic castration-resistant prostate cancer were observed \nto have a tolerable safety profile when treated with...', 'thumbnail': 'https://serpapi.com/searches/6723f2425bb6a2a9d05e9986/images/d0b79c8c13bfa29701ae4b41a1ce7e4e40409f748c62aa46b828a2ab239516f6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.665687620639801}",,,,,,,,,,['neutral'],neutral,1 NCT02602119,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-30265-z', 'title': 'Targeted detection of cancer at the cellular level during biopsy by near-infrared confocal laser endomicroscopy', 'source': 'Nature', 'date': 'May 17, 2022', 'snippet': 'Suspicious nodules detected by radiography are often investigated by \nbiopsy, but the diagnostic yield of biopsies of small nodules is poor.', 'thumbnail': 'https://serpapi.com/searches/6723f24b17b10eb84e16b634/images/dfcc126537b6fb008a0cfb3c43799e1e90b26b7ad61baa82164990e55805e009.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6216023564338684}",,,,,,,,,,['neutral'],neutral,1 NCT02676986,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-022-01849-9', 'title': 'Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer | British Journal of Cancer', 'source': 'Nature', 'date': 'May 26, 2022', 'snippet': 'Radiation therapy (RT) and hormone receptor (HR) inhibition are used for \nthe treatment of HR-positive breast cancers; however,...', 'thumbnail': 'https://serpapi.com/searches/6723f25181bab7b92fca11b7/images/b59be5951b2a73ec731203f3603459e18a1518c13842f60715d1f4757ffb3518.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9168511033058167}",,,,,,,,,,['neutral'],neutral,1 NCT00918983,"{'position': 1, 'link': 'https://bphnews.com/news-posts/2017/06/07/studies-show-enlarged-prostate-therapy-fexapotide-improves-sexual-function/', 'title': 'Enlarged Prostate Therapy Fexapotide Actually Improves Patients’ Sexual Function, Studies Show', 'source': 'BPH News', 'date': 'Jun 7, 2017', 'snippet': 'Fexapotide triflutate improves the sexual functioning of men with an \nenlarged prostate, according to combined results of four Phase 3 clinical \ntrials.', 'thumbnail': 'https://serpapi.com/searches/6723f25a3b3c32388571a899/images/77af5d809809fed0c00dd6a3bcb1195e47d7a1f5ee94b554d57eb44cee76e57a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6826880574226379}",,,,,,,,,,['positive'],positive,1 NCT00974311,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1207506', 'title': 'Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy', 'source': 'The New England Journal of Medicine', 'date': 'Aug 15, 2012', 'snippet': 'In our phase 3, double-blind, placebo-controlled trial, we stratified 1199 \nmen with castration-resistant prostate cancer after chemotherapy...', 'thumbnail': 'https://serpapi.com/searches/6723f275aab36d0ca8ac0c3d/images/0531194e44e51d9c497f33eb4fe95c88cb816f4cc91a544e946c93d35efee574.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6584006547927856}",,,,,,,,,,['neutral'],neutral,1 NCT04004208,"{'position': 1, 'link': 'https://www.empr.com/home/news/eylea-approved-for-preterm-infants-with-retinopathy-of-prematurity/', 'title': 'Eylea Approved for Preterm Infants With Retinopathy of Prematurity', 'source': 'Medical Professionals Reference', 'date': 'Feb 9, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Eylea (aflibercept) for \nthe treatment of preterm infants with retinopathy of prematurity (ROP).', 'thumbnail': 'https://serpapi.com/searches/6723f2784677bf90f1c1a308/images/10fc36e966b742e8ee7edf504689538d53521c3e11bae103835726fba0a4501e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8532078266143799}",,,,,,,,,,['neutral'],neutral,1 NCT01588132,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-91165-8', 'title': 'In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα', 'source': 'Nature', 'date': 'Jun 3, 2021', 'snippet': 'The interaction of platelet GPIbα with von Willebrand factor (VWF) is \nessential to initiate platelet adhesion and thrombosis,...', 'thumbnail': 'https://serpapi.com/searches/6723f282544c49d507809eef/images/8b4c601291c8d0dccce32be2c7b2e548c0c33206a83701ff6d17bd2b55ce90ea.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'Dec 13, 2019', 'snippet': 'Some patients with B-cell non-Hodkin lymphoma Lymphoma (NHL) become \nrefractory to rituximab (anti-CD20 antibody) therapy associated with...', 'thumbnail': 'https://serpapi.com/searches/6723f2cfc024d1be854f2256/images/d7ef6b2bc3b0024d2d6818c5cbd8483d10ea5d55ebb3385ccb5472d2ffe748d5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7524910569190979}",,,,,,,,,,['neutral'],neutral,1 NCT02657889,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-020-15315-8', 'title': 'Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer', 'source': 'Nature', 'date': 'Mar 19, 2020', 'snippet': 'Combined PARP and immune checkpoint inhibition has yielded encouraging \nresults in ovarian cancer, but predictive biomarkers are lacking.', 'thumbnail': 'https://serpapi.com/searches/6723f2dec0028efea8a60b55/images/b256625247414e9734381e0b32b06877bfd4cd56f2e0001edc86f63b51c3d77c.png', 'sentiment': 'neutral', 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'snippet': 'Fremanezumab as a preventive treatment for chronic migraine resulted in a \nlower frequency of headache than placebo in this 12-week trial.', 'thumbnail': 'https://serpapi.com/searches/6723f3012c83d5b81af4bd21/images/4058d5e5ee78736f45fa83733c98bb4dc2c9c5f18fa498cf922fc75789fb24ae.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8298872113227844}",,,,,,,,,,['neutral'],neutral,1 NCT05116891,"{'position': 1, 'link': 'https://www.notimerica.com/comunicados/noticia-comunicado-cantargia-presents-new-data-at-sitc-2022-supporting-nadunolimabs-promising-antitumor-clinical-efficacy-20221107141601.html', 'title': ""Cantargia presents new data at SITC 2022 supporting nadunolimab's promising antitumor clinical efficacy"", 'source': 'Notimérica', 'date': 'Nov 7, 2022', 'snippet': 'Data shows nadunolimab dual mechanism potently reduces levels of \ntumor-promoting molecules. LUND, Sweden, Nov.', 'thumbnail': 'https://serpapi.com/searches/6723f303f963e7f4ae6a7e46/images/99074ebc9056637adb7e09eef92d1c02dc61e584e92609e9390d6399abdb24b2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8620907068252563}","{'position': 2, 'link': 'https://www.notimerica.com/comunicados/noticia-comunicado-cantargia-asco-2022-presentation-strengthens-positive-phase-iia-interim-results-for-nadunolimab-in-nsclc-20220527002150.html', 'title': 'Cantargia: ASCO 2022 presentation strengthens positive phase IIa interim results for nadunolimab in NSCLC', 'source': 'Notimérica', 'date': 'May 26, 2022', 'snippet': 'today reported updated interim results for non-small cell lung cancer \n(NSCLC) patients treated with...', 'thumbnail': 'https://serpapi.com/searches/6723f303f963e7f4ae6a7e46/images/99074ebc9056637a257cadb1c1bde98f4cbc545eed6d94d47deb00fce7742583.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5094895958900452}","{'position': 3, 'link': 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confirming promising effects of nadunolimab in treatment of pancreatic c', 'source': 'Notimérica', 'date': 'May 26, 2022', 'snippet': '(NASDAQ Stockholm: CANTA) today reported extended interim results in \nfirst-line pancreatic cancer (PDAC)...', 'thumbnail': 'https://serpapi.com/searches/6723f303f963e7f4ae6a7e46/images/99074ebc9056637a17bb522f23f9f207dc2e7a2a9fbde8eef2193ef2f19131ad.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7977784276008606}",,,,,,,"['positive', 'positive', 'positive', 'positive']",positive,1 NCT00496769,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1107039', 'title': 'Apixaban versus Warfarin in Patients with Atrial Fibrillation', 'source': 'The New England Journal of Medicine', 'date': 'Aug 30, 2011', 'snippet': 'In patients with atrial fibrillation, apixaban was superior to warfarin in \npreventing stroke or systemic embolism, caused less bleeding, and resulted \nin lower...', 'thumbnail': 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Fails to Show Benefits of Tominersen', 'source': ""Huntington's Disease News"", 'date': 'May 6, 2021', 'snippet': ""Treatment with tominersen failed to show evidence of clinical benefit in \nadults with Huntington's disease during the Phase 3 trial..."", 'thumbnail': 'https://serpapi.com/searches/6723f3508b7ba7dbdcee4b59/images/4f9464099dbdccf098a0e6e02a3ce03aeb61f188cecadeadc0f8e1beaa4ca4a6.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7655267715454102}",,,,,,,,,,['negative'],negative,0 NCT03385928,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/STROKEAHA.123.043209', 'title': 'Exploring Hematoma Expansion Shift With Recombinant Factor VIIa: A Pooled Analysis of 4 Randomized Controlled Trials', 'source': 'American Heart Association Journals', 'date': 'Oct 8, 2023', 'snippet': 'rFVIIa (recombinant factor VIIa) is a hemostatic agent that reduces \nhematoma expansion in patients presenting with acute intracerebral \nhemorrhage (ICH).', 'thumbnail': 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PSA-PFS2 was prolonged with the...', 'thumbnail': 'https://serpapi.com/searches/6723f42b76585795dffb18f3/images/7db0850cfd3d35e9ad32963e023bf87019c1568bac26b78948896036d4720419.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8476401567459106}",,,,,,,,,,['neutral'],neutral,1 NCT02416453,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-022-00564-z', 'title': 'Non-human primate to human immunobridging demonstrates a protective effect of Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola | npj Vaccines', 'source': 'Nature', 'date': 'Nov 30, 2022', 'snippet': 'Without clinical efficacy data, vaccine protective effect may be \nextrapolated from animals to humans using an immunologic marker that...', 'thumbnail': 'https://serpapi.com/searches/6723f431059caf911a6bd567/images/957d7d769de9f46eb67ac5db20ad63b70c12cf3686adb0823cf021c3ffc8b6eb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8734168410301208}",,,,,,,,,,['neutral'],neutral,1 NCT01180036,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1814427', 'title': 'Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy', 'source': 'The New England Journal of Medicine', 'date': 'Jul 3, 2019', 'snippet': 'Rituximab was noninferior to cyclosporine in inducing complete or partial \nremission of proteinuria at 12 months and was superior in maintaining \nproteinuria...', 'thumbnail': 'https://serpapi.com/searches/6723f563577da558bd156352/images/f4020a96b72d8e1963c6ae667a694bbc8d79acae4dd9d70a96e6de53dd3e3105.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8242969512939453}",,,,,,,,,,['neutral'],neutral,1 NCT03472040,"{'position': 1, 'link': 'https://angioedemanews.com/news/orladeyo-set-to-launch-by-years-end-if-approved-biocryst-says/', 'title': ""HAE Drug Orladeyo to Launch by Year's End if Approved, BioCryst Says"", 'source': 'Angioedema News', 'date': 'Aug 19, 2020', 'snippet': ""BioCryst Pharmaceuticals will launch Orladeyo (berotralstat) by year's end \nif this oral drug for hereditary angioedema is approved,..."", 'thumbnail': 'https://serpapi.com/searches/6723f59af79a01c19a37e29e/images/7a0a9bdf3eaeae913632f2ef107615c27ab81f409409dcb1a3f8e4bf718abda7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.840570867061615}","{'position': 2, 'link': 'https://angioedemanews.com/news/argentina-approves-orladeyo-prevent-hae-attacks/', 'title': 'Argentina approves oral Orladeyo to prevent HAE attacks', 'source': 'Angioedema News', 'date': 'Dec 7, 2023', 'snippet': ""Argentina's regulatory body has approved Orladeyo to prevent swelling \nattacks in adults and adolescents, ages 12 and older, with HAE."", 'thumbnail': 'https://serpapi.com/searches/6723f59af79a01c19a37e29e/images/7a0a9bdf3eaeae9186561844e9d4055f8759ace30256017cfb54271c94a1ce82.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8729593753814697}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04737876,"{'position': 1, 'link': 'https://ibdnewstoday.com/2021/02/08/biomxs-ibd-phage-therapy-bx002-shows-promise-first-in-human-clinical-trial/', 'title': ""BiomX's IBD Phage Therapy BX002 Shows Promise in First-in-human Trial"", 'source': 'IBD News Today', 'date': 'Feb 8, 2021', 'snippet': 'BX002, an oral phage therapy BiomX is developing for inflammatory bowel \ndisease (IBD), showed a good safety profile, as well as the ability to \neffectively...', 'thumbnail': 'https://serpapi.com/searches/6723f4ec69012193a5fecbd2/images/e2e1f06e8961c0ae72b928ff505f2a25b87af5d270eb7328760c4f347b464254.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6927630305290222}",,,,,,,,,,['positive'],positive,1 NCT00781391,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1310907', 'title': 'Edoxaban versus Warfarin in Patients with Atrial Fibrillation', 'source': 'The New England Journal of Medicine', 'date': 'Nov 19, 2013', 'snippet': 'We conducted a randomized, double-blind, double-dummy trial comparing two \nonce-daily regimens of edoxaban with warfarin in 21,105 patients...', 'thumbnail': 'https://serpapi.com/searches/6723f4f9d771bdf6b3351c2e/images/fee46ccd9eba223f404a82dc65abc33692d0a671c9bd3943e3c600376a46e5d9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9197425246238708}",,,,,,,,,,['neutral'],neutral,1 NCT03815825,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/ionis-partner-licenses-rare-kidney-disease-treatment-and-will-advance-into-phase-3-clinical-study-301583315.html', 'title': 'Ionis partner licenses rare kidney disease treatment and will advance into Phase 3 clinical study', 'source': 'PR Newswire', 'date': 'Jul 11, 2022', 'snippet': 'PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS), today announced \nthat its long-standing partner, Roche, will license and advance...', 'thumbnail': 'https://serpapi.com/searches/6723f5439062f85c40db746d/images/6be8dd3e0f68c8711d67161a5fad28e3f0a90f9ff32fc8ac88accaf1600fa074.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.672743022441864}",,,,,,,,,,['neutral'],neutral,1 NCT01474512,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1512711', 'title': 'Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis', 'source': 'The New England Journal of Medicine', 'date': 'Jun 8, 2016', 'snippet': 'Ixekizumab, a monoclonal antibody against interleukin-17A, was superior to \nplacebo and etanercept in the treatment of moderate-to-severe psoriasis.', 'thumbnail': 'https://serpapi.com/searches/6723f54581262ade5a9c4e9a/images/ad6be2d26caeea1e04fd3a74e46cc5bb98d061d6ced3292d9cd5521e963ced12.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7625470161437988}","{'position': 2, 'link': 'https://psoriasisnewstoday.com/2017/02/14/study-shows-retreatment-of-psoriasis-with-taltz-after-interruption-of-therapy-is-effective/', 'title': 'Retreatment of Psoriasis with Taltz after Interruption in Therapy Is Effective, Study Suggests', 'source': 'Psoriasis News Today', 'date': 'Feb 14, 2017', 'snippet': 'Retreatment with Taltz (ixekizumab), after the end of initial treatment led \nto a relapse, restored response in most psoriasis patients, according to a \nstudy.', 'thumbnail': 'https://serpapi.com/searches/6723f54581262ade5a9c4e9a/images/ad6be2d26caeea1e398137c97d598f3520e2348ca32f96782b1c3183da15a7fd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6104496717453003}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04476017,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/dalzanemdor-sage-718-fails-improve-cognition-phase-2-trial/', 'title': 'Dalzanemdor, formerly SAGE-718, fails to aid cognition in Phase 2 trial', 'source': ""Parkinson's News Today"", 'date': 'Apr 24, 2024', 'snippet': ""Dalzanemdor (formerly SAGE-718), a medication for mild cognitive impairment \ndue to Parkinson's, failed to outperform a placebo in a trial."", 'thumbnail': 'https://serpapi.com/searches/6723f467fda26d2cf83e91fe/images/c9978c0864ffbbcee219ce1c11f9dc293b83a239ee3e52d88e94d6261c651b02.png', 'sentiment': 'negative', 'sentiment_prob': 0.8312615752220154}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/sage-718-showing-potential-aid-cognition-phase-2-paradigm-trial/', 'title': 'SAGE-718 Showing Potential to Aid Patients’ Thinking, Memory in Trial', 'source': ""Parkinson's News Today"", 'date': 'Mar 18, 2022', 'snippet': ""Early results from the Phase 2 clinical trial of oral SAGE-718 showed the \ninvestigative therapy's use was associated with cognitive gains in people \nwith mild..."", 'thumbnail': 'https://serpapi.com/searches/6723f467fda26d2cf83e91fe/images/c9978c0864ffbbceabd996a0070eac5de57da57fba41d4d4dc07ee004f20102d.png', 'sentiment': 'positive', 'sentiment_prob': 0.5563304424285889}",,,,,,,,,"['negative', 'positive']",negative,0 NCT02851797,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00036-X/fulltext', 'title': 'Safety and efficacy of givinostat in boys with Duchenne muscular dystrophy (EPIDYS): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'Apr 18, 2024', 'snippet': 'Duchenne muscular dystrophy, the most common childhood muscular dystrophy, \nis caused by dystrophin deficiency. 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(givinostat), a newly approved treatment for Duchenne muscular \ndystrophy (DMD), is now available in the US.', 'thumbnail': 'https://serpapi.com/searches/6723f49ac5d7698b697f62e7/images/35d00584df105161833372b05a6e30ad9c4d61174e166e4ea0bd3e99bbb72aba.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5288257598876953}","{'position': 8, 'link': 'https://www.contractpharma.com/contents/view_breaking-news/2024-03-22/italfarmaco-spas-duvyzat-approved-by-fda/', 'title': 'Italfarmaco S.p.A.’s Duvyzat Approved By FDA', 'source': 'Contract Pharma', 'date': 'Mar 22, 2024', 'snippet': 'Orally administered treatment for Duchenne muscular dystrophy approved in \npatients 6 years and older.', 'thumbnail': 'https://serpapi.com/searches/6723f49ac5d7698b697f62e7/images/35d00584df105161298b4978f2051a916dc1c6e1f77cde7a360a3c95cda3e170.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7186108827590942}","{'position': 9, 'link': 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'While the majority of renal cell carcinoma (RCC) cases present at an early \nstage, a significant number of patients are diagnosed with either locally...', 'thumbnail': 'https://serpapi.com/searches/6723f4bf7f3719505b760612/images/0fcccebfe7e5973bc87d78ed8efb645c3861106cabe37d9306fcdcadbdf633c3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8618273138999939}",,,,,,,,,,['neutral'],neutral,1 NCT02664181,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1122352/full', 'title': 'Prospects and feasibility of synergistic therapy with radiotherapy, immunotherapy, and DNA methyltransferase inhibitors in non-small cell lung cancer', 'source': 'Frontiers', 'date': 'Feb 8, 2024', 'snippet': 'The morbidity and mortality of lung cancer are increasing, seriously \nthreatening human health and life. Non-small cell lung cancer (NSCLC) has \nan insidious...', 'thumbnail': 'https://serpapi.com/searches/6723f4d4efad2183fae89338/images/038e818be8cc580f7f85e929ebde9d46f67e57171f6c4d790a364806184650ab.png', 'sentiment': 'negative', 'sentiment_prob': 0.6864020824432373}",,,,,,,,,,['negative'],negative,0 NCT00471497,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-020-01111-2', 'title': 'Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis', 'source': 'Nature', 'date': 'Jan 7, 2021', 'snippet': 'In the ENESTnd study, with ≥10 years follow-up in patients with newly \ndiagnosed chronic myeloid leukemia (CML) in chronic phase,...', 'thumbnail': 'https://serpapi.com/searches/6723f5b754605c243c1bb941/images/86555888f480f6b3b5589756bdf6595c48a27dba987615133e748eeb139d8cd3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8985676765441895}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0912614', 'title': 'Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'Jan 26, 2017', 'snippet': 'Nilotinib at a dose of either 300 mg or 400 mg twice daily was superior to \nimatinib in patients with newly diagnosed chronic-phase Philadelphia \nchromosome–...', 'thumbnail': 'https://serpapi.com/searches/6723f5b754605c243c1bb941/images/86555888f480f6b3c6c3f8771b5eef0755b5f1eb5c3942266d3350e21a0c0c50.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8109325170516968}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03410992,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-bimzelx-for-plaque-psoriasis/', 'title': 'FDA Approves Bimzelx for Moderate to Severe Plaque Psoriasis', 'source': 'Medical Professionals Reference', 'date': 'Oct 18, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Bimzelx \n(bimekizumab-bkzx) for the treatment of moderate to severe plaque psoriasis \nin adults.', 'thumbnail': 'https://serpapi.com/searches/6723f5bedb3ac91c61a1f5a2/images/5447b7517d385d6808951bc671677b21c5ce91e7bf2cf82d001dae076c231a1c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7481014132499695}",,,,,,,,,,['neutral'],neutral,1 NCT05113862,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01557-7', 'title': 'Vaccine adjuvants: mechanisms and platforms - Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': '١٩\u200f/٠٧\u200f/٢٠٢٣', 'snippet': 'Adjuvants are defined as various components that enhance the immunogenicity \nof vaccines when administered in conjunction with vaccine antigens.', 'thumbnail': 'https://serpapi.com/searches/6723f5d2b691a7acb28e8e16/images/2913b499c27b8f183b07ddff972f6f30504b64582f2c9b83f338fe11c20f1e89.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9136331677436829}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/ddr.21969', 'title': 'The potential of developing a protective peptide‐based vaccines against SARS‐CoV‐2', 'source': 'Wiley Online Library', 'date': '٢٥\u200f/٠٦\u200f/٢٠٢٢', 'snippet': 'Peptide-based vaccines hold great promise in countering COVID-19 as they \nmay overcome most of the shortcomings of RNA/DNA and protein vaccines.', 'thumbnail': 'https://serpapi.com/searches/6723f5d2b691a7acb28e8e16/images/2913b499c27b8f18f7413e8193f2942ac147ab1ba020f750e921d3c71ae51482.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.824072003364563}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT00783718,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1215734', 'title': 'Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis', 'source': 'The New England Journal of Medicine', 'date': 'Aug 22, 2013', 'snippet': 'We conducted two integrated randomized, double-blind, placebo-controlled \ntrials of vedolizumab in patients with active disease.', 'thumbnail': 'https://serpapi.com/searches/6723f5e506f4f28543e6b8ad/images/116b9ed7297dec5c1632bc2991d026448a706ca5dba67db4d2eb93be1a923895.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8720484972000122}",,,,,,,,,,['neutral'],neutral,1 NCT01179217,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1715971', 'title': 'A Phase 3 Trial of l-Glutamine in Sickle Cell Disease | NEJM', 'source': 'The New England Journal of Medicine', 'date': 'Jul 18, 2018', 'snippet': 'Oxidative stress contributes to the complex pathophysiology of sickle cell \ndisease. Oral therapy with pharmaceutical-grade l-glutamine (USAN...', 'thumbnail': 'https://serpapi.com/searches/6723f5fa5ddfba8fdaa1f67e/images/3b90aa2aceafa49b7e455575ba44063d9b8c645abbe9a874c115e0a504a81a08.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7132492661476135}","{'position': 2, 'link': 'https://sicklecellanemianews.com/news/emmaus-seeks-approval-oral-endari-medication-scd-kuwait/', 'title': 'Emmaus Seeks Approval of Oral Medication Endari in Kuwait', 'source': 'Sickle Cell Disease News', 'date': 'Jul 20, 2021', 'snippet': 'Emmaus Life Sciences has submitted an application seeking the approval of \nEndari as a treatment for sickle cell disease in Kuwait.', 'thumbnail': 'https://serpapi.com/searches/6723f5fa5ddfba8fdaa1f67e/images/3b90aa2aceafa49b9e8126dc8aa5b87d845d0f4afb37ca224a7c362034bcc252.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921515703201294}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01006980,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1103782', 'title': 'Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation', 'source': 'The New England Journal of Medicine', 'date': 'Aug 2, 2014', 'snippet': 'Phase 1 and 2 clinical trials of the BRAF kinase inhibitor vemurafenib \n(PLX4032) have shown response rates of more than 50% in patients with \nmetastatic...', 'thumbnail': 'https://serpapi.com/searches/6723f5feeda5f52faf00ead7/images/673a74dc58b71259c482630f91cf506be2ad2ae7d45e0f4767d16e290b212ed7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5213320851325989}",,,,,,,,,,['neutral'],neutral,1 NCT02852551,"{'position': 1, 'link': 'https://lungdiseasenews.com/2017/08/28/pharmaakea-completes-phase-1-clinical-trial-of-pulmonary-fibrosis-therapy-pat-1251/', 'title': ""Pulmonary Fibrosis Therapy PAT-1251's Phase 1 Clinical Trial Is Over"", 'source': 'Lung Disease News', 'date': 'Aug 28, 2017', 'snippet': 'Read about PharmaAkea completing a Phase 1 clinical trial indicating that \nits PAT-1251 therapy binds with an enzyme linked to pulmonary...', 'thumbnail': 'https://serpapi.com/searches/6723f600c024d1be4923cc1e/images/45a6acd3fcad479b75dba4af6a70b620dd5f54234760742cc028e5e8b7d5d820.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8932006359100342}",,,,,,,,,,['neutral'],neutral,1 NCT00811889,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1105351', 'title': 'Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Jun 24, 2011', 'snippet': 'Chronic kidney disease (CKD) associated with type 2 diabetes is the leading \ncause of kidney failure, with both inflammation and oxidative...', 'thumbnail': 'https://serpapi.com/searches/6723f6262c566d38f2509662/images/6875fdd9c432581ab51c5b7e91da4aead8fd10f73a1767eefbb99bfb19464c71.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6634526252746582}",,,,,,,,,,['negative'],negative,0 NCT01743651,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/arbaclofen-er-tablets-similar-potency-spasticity-baclofen/', 'title': 'Arbaclofen ER Tablets Show Similar Potency for Spasticity as Baclofen', 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 28, 2019', 'snippet': 'Read about how arbaclofen extended-release tablets can reduce spasticity in \npatients with MS similarly to the standard baclofen treatment.', 'thumbnail': 'https://serpapi.com/searches/6723f66fdda9d9effefd2cf1/images/9c0981ac99c62e3ac2fecf101ed992d6d881756a3d660317fb47891b9bc0c4ff.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7216485738754272}",,,,,,,,,,['neutral'],neutral,1 NCT02684058,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02321-8', 'title': 'Dabrafenib plus trametinib in BRAFV600E -mutated rare cancers: the phase 2 ROAR trial', 'source': 'Nature', 'date': 'Apr 14, 2023', 'snippet': 'Here we present final efficacy and safety results of a phase 2 basket trial \nof dabrafenib (BRAF kinase inhibitor) plus trametinib (MEK inhibitor) in \neight...', 'thumbnail': 'https://serpapi.com/searches/6723f674be324f9cf1aca366/images/e319749236215c96937db7bd6f44afbf2b94a54915a5723960cf05372c1ae868.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8969771862030029}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2303815', 'title': 'Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations', 'source': 'The New England Journal of Medicine', 'date': 'Sep 20, 2023', 'snippet': 'Detection of the BRAF V600E mutation in pediatric low-grade glioma has been \nassociated with a lower response to standard chemotherapy.', 'thumbnail': 'https://serpapi.com/searches/6723f674be324f9cf1aca366/images/e319749236215c965adbcf746026cdf03d3a5cc376ccd18757cff0caf28f04e2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5143287777900696}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/fda-approves-dabrafenib-plus-trametinib-in-low-grade-glioma-with-braf-v600e-mutation', 'title': 'FDA Approves Dabrafenib Plus Trametinib in Low-Grade Glioma With BRAF V600E Mutation', 'source': 'Cancer Network', 'date': 'Mar 17, 2023', 'snippet': 'Results from the phase 2 CDRB436G2201 trial lead to the approval of \ndabrafenib plus trametinib in patients with low-grade glioma and a BRAF...', 'thumbnail': 'https://serpapi.com/searches/6723f674be324f9cf1aca366/images/e319749236215c9693f823591419f861d09c32a3e1e391da44bd03ff37014a49.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7758387327194214}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03056339,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02785-8', 'title': 'Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19', 'source': 'Nature', 'date': 'Jan 18, 2024', 'snippet': 'We conducted a phase 1/2 trial of cord blood-derived natural killer (NK) \ncells expressing anti-CD19 chimeric antigen receptor and interleukin-15 \n(CAR19/IL-15)...', 'thumbnail': 'https://serpapi.com/searches/6723f695e335ec8a493129fa/images/e40530aee34749f3d864f929b74ef84da37f0dfb637e3f10466560810e2d1422.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8290050029754639}","{'position': 2, 'link': 'https://lymphomanewstoday.com/2020/02/25/car-nk-cells-demonstrate-high-response-rate-safety-lymphoma-leukemia-early-trial/', 'title': 'NHL, CLL Respond to Anti-CD19 CAR NK Cell Therapy, Early Data Show', 'source': 'Lymphoma News Today', 'date': 'Feb 25, 2020', 'snippet': ""CAR NK cells targeting CD19 show a high response rate and safety in \nnon-Hodgkin's lymphoma and chronic lymphocytic leukemia, early trial..."", 'thumbnail': 'https://serpapi.com/searches/6723f695e335ec8a493129fa/images/e40530aee34749f3d1c4359a979a19e7ed06f7bf161ff2bd977e7f235f43729e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6805907487869263}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03259074,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2018/01/10/phase-3-trial-in-ankylosing-spondylitis-compares-cosentyx-to-adalimumab-biosimilar/', 'title': 'Novartis Initiates Phase 3 Trial in AS Comparing Cosentyx to Adalimumab Biosimilar', 'source': 'Ankylosing Spondylitis News', 'date': 'Jan 10, 2018', 'snippet': 'Novartis recently initiated a Phase 3 clinical trial comparing its \nFDA-approved therapy Cosentyx (secukinumab) with GP2017 — an adalimumab...', 'thumbnail': 'https://serpapi.com/searches/6723f797e50bc005c852d2cf/images/cb25c26f190dc35628bc76b7778a48d95e56e25de1810de432661a43fe62f5eb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9141103625297546}",,,,,,,,,,['neutral'],neutral,1 NCT04105010,"{'position': 1, 'link': 'https://www.onclive.com/view/golidocitinib-nda-under-nmpa-review-for-relapsed-refractory-ptcl', 'title': 'Golidocitinib NDA Under NMPA Review for Relapsed/Refractory PTCL', 'source': 'OncLive', 'date': 'Sep 14, 2023', 'snippet': ""The Center for Drug Evaluation of China's National Medical Products \nAdministration has accepted the new drug application seeking the approval \nof golidocitinib."", 'thumbnail': 'https://serpapi.com/searches/6723f7a4d771bdf678dc5166/images/0677b2284a34c9fe4505e2e3bb13e00eee55b6d3d601fd4c74634d6cb476c7d4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9207753539085388}","{'position': 2, 'link': 'https://lymphomahub.com/medical-information/phase-i-data-of-golidocitinib-rr-peripheral-t-cell-lymphoma-jackpot8-trial', 'title': 'Phase I data of golidocitinib for R/R peripheral T-cell lymphoma: JACKPOT8 trial', 'source': 'Lymphoma Hub', 'date': 'Aug 8, 2022', 'snippet': 'The study met its primary endpoint, elucidating the adverse events \nassociated with golidocitinib in patients with R/R PTCL.', 'thumbnail': 'https://serpapi.com/searches/6723f7a4d771bdf678dc5166/images/0677b2284a34c9fe5aa5826a51518b6d90e9501e6ce61a14c1a808605656689e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7840216755867004}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02700685,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S1756464622003164', 'title': 'Clinical Investigation of French Maritime Pine Bark Extract on Attention-Deficit Hyperactivity Disorder as compared to Methylphenidate and Placebo: Part 1: Efficacy in a Randomised Trial', 'source': 'ScienceDirect.com', 'date': 'Sep 14, 2022', 'snippet': 'PBE is a valuable treatment option in paediatric ADHD especially for those \nnot willing to take standard medication or experiencing side effects.', 'thumbnail': 'https://serpapi.com/searches/6723f7c7d910393e41a1ada7/images/1c4e5c0c6e597d9984782d43b06aa9d050f52be4ca81e8472d1d2b2410e9213f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6286596655845642}",,,,,,,,,,['neutral'],neutral,1 NCT01450761,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01522-4', 'title': 'Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends', 'source': 'Nature', 'date': 'Aug 28, 2023', 'snippet': 'Immune checkpoint blockade (ICB) drugs have been initially approved as \nearly as 2011 for the treatment of unresectable advanced melanoma after \nclassical...', 'thumbnail': 'https://serpapi.com/searches/6723f7d70f1a3393cf1ee9f4/images/319790ffd2cb8dcae8680166a1065ee310e3c4fb23e23bc694b3eeb5845c986e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8954232335090637}",,,,,,,,,,['neutral'],neutral,1 NCT04147234,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1485546/full', 'title': 'Clinical applications of STING agonists in cancer immunotherapy: current progress and future prospects', 'source': 'Frontiers', 'date': '1 month ago', 'snippet': 'The STING (Stimulator of Interferon Genes) pathway is pivotal in activating \ninnate immunity, making it a promising target for cancer...', 'thumbnail': 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'https://ascopost.com/news/april-2023/update-on-withdrawal-of-ibrutinib-accelerated-approvals-for-mcl-and-mzl-in-the-united-states/', 'title': 'Update on Withdrawal of Ibrutinib Accelerated Approvals for MCL and MZL in the United States', 'source': 'The ASCO Post', 'date': 'Apr 12, 2023', 'snippet': 'AbbVie announced that it intends to voluntarily withdraw, in the United \nStates, accelerated ibrutinib (Imbruvica) approvals for patients with \nmantle cell...', 'thumbnail': 'https://serpapi.com/searches/6723f6b603775653ac4aa78c/images/bcefa027bc9f9948481c1e3a27546d39bf48ed0cf610a25ae1e5330c21d3be4c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9219139218330383}","{'position': 2, 'link': 'https://www.clinicalleader.com/doc/new-fda-guidance-clinical-trial-considerations-to-support-accelerated-approval-of-oncology-therapeutics-0001', 'title': 'New FDA Guidance Clinical Trial Considerations To Support Accelerated Approval Of Oncology Therapeutics', 'source': 'Clinical Leader', 'date': 'Apr 21, 2023', 'snippet': 'On April 6, 2023, AbbVie announced that it was voluntarily withdrawing \nibrutinib, which was granted accelerated approval for two...', 'thumbnail': 'https://serpapi.com/searches/6723f6b603775653ac4aa78c/images/bcefa027bc9f994812730fed0a84a663e6c6e37cb34d78642578c64436714fe7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8708025217056274}","{'position': 3, 'link': 'https://www.cancertherapyadvisor.com/news/imbruvica-no-longer-approved-to-treat-mcl-mzl/', 'title': 'Imbruvica No Longer Approved to Treat MCL, MZL in the US', 'source': 'Cancer Therapy Advisor', 'date': 'Apr 12, 2023', 'snippet': 'Janssen and AbbVie are withdrawing the accelerated approvals of Imbruvica \n(ibrutinib) for mantle cell lymphoma (MCL) and marginal zone lymphoma (MZL)', 'thumbnail': 'https://serpapi.com/searches/6723f6b603775653ac4aa78c/images/bcefa027bc9f9948d1d35565e18d0dce7257fe236450a5166ef0bb56495461c0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Pulmonology Advisor', 'date': 'Oct 3, 2022', 'snippet': 'Long-term sotatercept use may allow patients with PAH to maintain \nsignificantly reduced pulmonary vascular resistance.', 'thumbnail': 'https://serpapi.com/searches/6723f6cd861b9d63abef856a/images/248f9e1bdd18e9cd3211f76c79a1a00aa406c707529239c749146445b1f4aaee.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6029508709907532}",,,,,,,,,,['positive'],positive,1 NCT04510987,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062353', 'title': 'Pharmacology and Clinical Development of Factor XI Inhibitors | Circulation', 'source': 'American Heart Association Journals', 'date': 'Mar 13, 2023', 'snippet': 'This article reviews the rationale, pharmacology, results of medium or \nsmall phase 2 studies, and future perspectives of drugs inhibiting FXI.', 'thumbnail': 'https://serpapi.com/searches/6723f6e1c5d7698b996f414d/images/8d805aec9677b7e5d5576fee3e4ad60efb4d6bb83b10a01c5109e82410882a4e.png', 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'source': 'European Pharmaceutical Review', 'date': 'May 26, 2021', 'snippet': 'In a trial pegcetacoplan resulted in 86 percent of paroxysmal nocturnal \nhaemoglobinuria (PNH) patients achieving haemoglobin stabilisation.', 'thumbnail': 'https://serpapi.com/searches/6723f8367e1d1fae374b52b0/images/f952a8f33bcf9f46b0757fb40ef27da49ef31990dd18743acb376f6180f2e96e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.694446861743927}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02926066,"{'position': 1, 'link': 'https://www.cgtlive.com/view/upstaza-approved-aadc-deficiency-uk', 'title': 'Upstaza Approved for AADC Deficiency in UK', 'source': 'CGTLive®', 'date': 'Nov 21, 2022', 'snippet': 'Upstaza (eladocagene exuparvovec), a recombinant adeno-associated virus \nserotype 2 (AAV2)-based gene therapy intended to treat aromatic L–amino \nacid...', 'thumbnail': 'https://serpapi.com/searches/6723f838b28e6b6e596dd7fa/images/6100cfe5bc6d2cf8f436d424b95de7974b98366c1e3111df5fd35696c2144680.jpeg', 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Taiwan University Hospital, about Upstaza as well as \nhis work in Pompe...', 'thumbnail': 'https://serpapi.com/searches/6723f838b28e6b6e596dd7fa/images/6100cfe5bc6d2cf8b3ea48da96895671925fa24375f7ceaad443e430db1d73ee.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9344761371612549}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02220894,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32409-7/fulltext', 'title': 'Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial', 'source': 'The Lancet', 'date': 'Apr 4, 2019', 'snippet': 'First-line pembrolizumab monotherapy improves overall and progression-free \nsurvival in patients with untreated metastatic non-small-cell...', 'thumbnail': 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Ensifentrine for Treatment of COPD', 'source': 'Drug Topics', 'date': 'Jun 27, 2024', 'snippet': 'The FDA has approved ensifentrine (Ohtuvayre) for the maintenance treatment \nof chronic obstructive pulmonary disease (COPD) in adult patients.', 'thumbnail': 'https://serpapi.com/searches/6723f84e74f0a4921704ea9e/images/96aeab566eed0a28a64eae68f8ecd0ebd40ff3ee439681d7426e9a684de1141b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7171338796615601}","{'position': 3, 'link': 'https://copdnewstoday.com/news/enhance-1-trial-testing-ensifentrine-copd-completes-enrollment/', 'title': 'Enrollment Complete – Tops 800 – in ENHANCE-1 Trial of Ensifentrine', 'source': 'COPD News Today', 'date': 'Jun 16, 2022', 'snippet': ""Enrollment is now complete in ENHANCE-1, a Phase 3 clinical trial testing \nVerona Pharma's experimental inhalation therapy ensifentrine in more than \n800 people."", 'thumbnail': 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The efficacy and safety of...', 'thumbnail': 'https://serpapi.com/searches/6723f84e7d533e68053dcb81/images/a81d4fd6a9e3186716d375b7d1f341601a4265a35cac770d8a76bb726f05772c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8939939141273499}",,,,,,,,,,['neutral'],neutral,1 NCT02279160,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/long-term-safety-and-tolerability-of-ralinepag-in-pah/', 'title': 'Long-Term Safety, Tolerability of Ralinepag in Pulmonary Arterial Hypertension', 'source': 'Pulmonology Advisor', 'date': 'May 31, 2022', 'snippet': 'An open-label extension study of the long-term safety of ralinepag for PAH \nfound a positive risk-benefit ratio similar to that of the parent...', 'thumbnail': 'https://serpapi.com/searches/6723f8620053c79278d24911/images/f8d2400354eec98a48dec93bd14601e108241e99edc4d55c0c22d2b789b18cbc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8393498659133911}",,,,,,,,,,['neutral'],neutral,1 NCT04508621,"{'position': 1, 'link': 'https://fibromyalgianewstoday.com/2020/09/08/enrollment-open-in-second-phase-3-trial-of-higher-tnx-102-sl-dose-for-managing-fm/', 'title': 'Enrollment Open in Second Phase 3 Trial of Higher TNX-102 SL Dose for Managing FM', 'source': 'Fibromyalgia News Today', 'date': 'Sep 8, 2020', 'snippet': ""The second Phase 3 clinical trial examining a higher dose of TNX-102 SL \n(sublingual cyclobenzaprine), Tonix Pharmaceuticals' bedtime..."", 'thumbnail': 'https://serpapi.com/searches/6723f8643c944b934c0ea887/images/f25750ad05bcba56b073a70acee5c8c6f1e1f2526beaff3f7ad12cbb48c0798a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9358941316604614}",,,,,,,,,,['neutral'],neutral,1 NCT03411161,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-66244-1', 'title': 'A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line', 'source': 'Nature', 'date': 'Jul 10, 2024', 'snippet': 'A genome-wide CRISPR interference and knockout screen in the PANC-1 cell \nline with the drug nab-paclitaxel has identified a group of spindle \nassembly...', 'thumbnail': 'https://serpapi.com/searches/6723f8ce29e6fb794b244596/images/87b717f17b63d8bd364298e8933ca8d5c46ff57325c8812ec6cafcccfba70d7a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.834575355052948}",,,,,,,,,,['neutral'],neutral,1 NCT01006265,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/08/30/long-term-ponvory-treatment-safe-effective-rrms-trial-data/', 'title': 'Long-term Ponvory Treatment Safe, Effective in RRMS, Trial Data Show', 'source': 'Multiple Sclerosis News Today', 'date': 'Aug 30, 2022', 'snippet': 'Long-term treatment with Ponvory was found to reduce the rate of relapses \nand prevent brain volume loss in relapsing-remitting MS patients.', 'thumbnail': 'https://serpapi.com/searches/6723f8ddfd3b5ae60890cbe8/images/56774a592d50f7103c602d762cc97475e35baa153c33819d1177acbfaddcaf9c.png', 'sentiment': 'positive', 'sentiment_prob': 0.6364147067070007}",,,,,,,,,,['positive'],positive,1 NCT01668849,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-27893-2', 'title': 'Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2', 'source': 'Nature', 'date': 'Jan 20, 2022', 'snippet': 'The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused \nthe pandemic of the coronavirus induced disease 2019 (COVID-19)...', 'thumbnail': 'https://serpapi.com/searches/6723f8eafc40bf5af06cdd46/images/730d53f9dd83ee82057ef990d07462fc160ab8baf3526857005582afacc1f914.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6649355888366699}",,,,,,,,,,['negative'],negative,0 NCT02574598,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.6453', 'title': 'The efficacy and safety of immune checkpoint inhibitors for patients with EGFR-mutated non-small cell lung cancer who progressed on EGFR tyrosine-kinase inhibitor therapy: A systematic review and network meta-analysis', 'source': 'Wiley Online Library', 'date': 'Aug 16, 2023', 'snippet': 'Cancer Medicine is an open access, broad-scope oncology journal covering \nclinical cancer research, cancer biology, cancer prevention,...', 'thumbnail': 'https://serpapi.com/searches/6723f8fbcc487953868270a7/images/1b0498b7b5e551d045efd01da8371fdb6e7b29d999c5b2b3756aa64ea2841390.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8414208889007568}",,,,,,,,,,['neutral'],neutral,1 NCT01639339,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2001180', 'title': 'Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 16, 2020', 'snippet': 'In this trial involving patients with active lupus nephritis, more patients \nwho received belimumab plus standard therapy had a primary efficacy renal \nresponse.', 'thumbnail': 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'https://cushingsdiseasenews.com/news/recorlev-approved-adults-endogenous-cushings-syndrome/', 'title': 'FDA Approves Recorlev for Adults With Endogenous Cushing’s', 'source': ""Cushing's Disease News"", 'date': 'Jan 5, 2022', 'snippet': ""The U.S. Food and Drug Administration (FDA) has approved Recorlev \n(levoketoconazole), and it's expected to be available early this year."", 'thumbnail': 'https://serpapi.com/searches/6723f9323d629b3e007c6607/images/4e2c9617c31fa424e3b9445dce47236e8cab478dda3780263c8c9ab8e1e19746.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5631511211395264}","{'position': 3, 'link': 'https://cushingsdiseasenews.com/news/approved-therapy-recorlev-granted-orphan-drug-exclusivity-fda/', 'title': 'Approved Therapy Recorlev Now Wins FDA Orphan-drug Exclusivity', 'source': ""Cushing's Disease News"", 'date': 'Feb 1, 2023', 'snippet': ""The FDA has granted Xeris Pharmaceuticals orphan-drug exclusivity for \nRecorlev, its approved treatment for endogenous Cushing's syndrome."", 'thumbnail': 'https://serpapi.com/searches/6723f9323d629b3e007c6607/images/4e2c9617c31fa424a4b319194511eb4d39f43565860465811b872af40bf8cf5f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5163628458976746}",,,,,,,,"['positive', 'neutral', 'neutral']",neutral,1 NCT03289455,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-021-01497-1', 'title': 'CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial', 'source': 'Nature', 'date': 'Oct 12, 2021', 'snippet': 'Chimeric antigen receptor (CAR) T cells targeting CD19 or CD22 have shown \nremarkable activity in B cell acute lymphoblastic leukemia (B-ALL).', 'thumbnail': 'https://serpapi.com/searches/6723f936f6aa534e9217e4ed/images/283c66684c722f6af40751f95efbd333ca1b8558302fc77ce7fc73fb05e0b885.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9159050583839417}",,,,,,,,,,['neutral'],neutral,1 NCT01524978,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-022-00341-0', 'title': 'BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study | npj Precision Oncology', 'source': 'Nature', 'date': 'Feb 18, 2023', 'snippet': 'We performed a pooled analysis of four phase one studies evaluating the \nsafety and efficacy of vemurafenib monotherapy and vemurafenib combined \nwith targeted...', 'thumbnail': 'https://serpapi.com/searches/6723f9567ac731b61c940734/images/7475048598d1cb8f44fad53f5e53d9b2a920fa975e62aee045dc6e3a5d7bd428.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9065907597541809}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1502309', 'title': 'Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations', 'source': 'The New England Journal of Medicine', 'date': 'Aug 20, 2015', 'snippet': 'We undertook a histology-independent phase 2 “basket” study of vemurafenib \nin BRAF V600 mutation–positive nonmelanoma cancers.', 'thumbnail': 'https://serpapi.com/searches/6723f9567ac731b61c940734/images/7475048598d1cb8f73c0341ef207cb1772cfac1d0e9ac9ba2febc7c88ee16d22.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9230263233184814}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03178487,"{'position': 1, 'link': 'https://www.empr.com/home/news/rinvoq-approved-for-active-ankylosing-spondylitis/', 'title': 'Rinvoq Approved for Active Ankylosing Spondylitis', 'source': 'Medical Professionals Reference', 'date': 'May 2, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Rinvoq (upadacitinib) \nfor the treatment of adults with active ankylosing spondylitis (AS).', 'thumbnail': 'https://serpapi.com/searches/6723f9570e6db3745b1e2a9e/images/9c20dbe67bfdff2ed57336fdc11d75bf5ac700e5f7763095fcf7e979c49915d7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7677649855613708}",,,,,,,,,,['neutral'],neutral,1 NCT04332276,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/study-review-highlights-limits-levodopa-effectiveness/', 'title': 'Study review highlights limits of levodopa effectiveness', 'source': ""Parkinson's News Today"", 'date': '1 month ago', 'snippet': 'Levodopa becomes less effective with age and disease progression, per a \nstudy from Inbrain, which is developing a new form of the treatment.', 'thumbnail': 'https://serpapi.com/searches/6723f9660c666800a3357139/images/5accb66396e6e202af249a6256b6a329ad40be5c07fc03a6a104c14e2c78fca1.png', 'sentiment': 'negative', 'sentiment_prob': 0.622397780418396}",,,,,,,,,,['negative'],negative,0 NCT01239797,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1505654', 'title': 'Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'Jun 2, 2015', 'snippet': 'In this phase 3 study, we randomly assigned patients to receive either \nelotuzumab plus lenalidomide and dexamethasone (elotuzumab group) or...', 'thumbnail': 'https://serpapi.com/searches/6723f99f8db3765529660de2/images/e220a1dcc5cb6e48155f31e432f35ecf1ab8e714da45db2af97f8ae53f0fed73.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9350350499153137}","{'position': 2, 'link': 'https://www.nature.com/articles/s41408-020-00357-4', 'title': 'Elotuzumab, lenalidomide, and dexamethasone in RRMM: final overall survival results from the phase 3 randomized ELOQUENT-2 study', 'source': 'Nature', 'date': 'Sep 4, 2020', 'snippet': 'Prolonging overall survival (OS) remains an unmet need in relapsed or \nrefractory multiple myeloma (RRMM). In ELOQUENT-2 (NCT01239797),...', 'thumbnail': 'https://serpapi.com/searches/6723f99f8db3765529660de2/images/e220a1dcc5cb6e489e63cbb9ffe26e6b7a165c8e03c5f185a46fcd45beacc232.png', 'sentiment': 'neutral', 'sentiment_prob': 0.806358814239502}","{'position': 3, 'link': 'https://www.nature.com/articles/bcj201718', 'title': 'Randomized phase 3 study of elotuzumab for relapsed or refractory multiple myeloma: ELOQUENT-2 Japanese patient subanalysis', 'source': 'Nature', 'date': 'Mar 10, 2017', 'snippet': 'A phase 3, international, randomized clinical trial that investigated the \nefficacy and safety of ELd compared with lenalidomide/dexamethasone (Ld) in \npatients...', 'thumbnail': 'https://serpapi.com/searches/6723f99f8db3765529660de2/images/e220a1dcc5cb6e48ff2059e61d32b4b531bd6deb4bca2a88b8c108e952b3a532.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9092058539390564}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01095497,"{'position': 1, 'link': 'https://angioedemanews.com/cinryze/', 'title': 'Cinryze (human C1 esterase inhibitor) for hereditary angioedema', 'source': 'Angioedema News', 'date': 'Jan 9, 2024', 'snippet': 'Cinryze, marketed by Shire, is an approved injectable medicine to prevent \nsevere swelling attacks in people with hereditary angioedema...', 'thumbnail': 'https://serpapi.com/searches/6723f9a252a04ebbcc463b3a/images/55044db00070d18dc0d9ed630e0508e1b49937ca3c679e1418f8f5dbd4dc4a9b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8004082441329956}",,,,,,,,,,['neutral'],neutral,1 NCT01979952,"{'position': 1, 'link': 'https://pulmonaryfibrosisnews.com/news/ipf-patients-live-longer-on-nintedanib-pooled-data-from-six-trials-show/', 'title': 'IPF Patients Live Longer on Ofev Compared with Placebo, Analysis Shows', 'source': 'Pulmonary Fibrosis News', 'date': 'Apr 16, 2019', 'snippet': 'Treatment with Ofev (nintedanib) can significantly extend the survival of \npatients with idiopathic pulmonary fibrosis (IPF), an analysis of pooled \ndata from...', 'thumbnail': 'https://serpapi.com/searches/6723f9c8213c87df4d44ab93/images/eec62ea8cf06b1de5906744c8456a634be4f3fa27f030868d3164578cf32006f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.544462263584137}",,,,,,,,,,['neutral'],neutral,1 NCT02623699,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2204705', 'title': 'Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS', 'source': 'The New England Journal of Medicine', 'date': 'Sep 21, 2022', 'snippet': 'Tofersen reduced concentrations of SOD1 in CSF and of neurofilament light \nchains in plasma over 28 weeks but did not improve clinical end points and \nwas...', 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b190f0e92739110ea961f5943abf999dabad2f47f465cc15d180.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5358057022094727}","{'position': 2, 'link': 'https://investors.biogen.com/news-releases/news-release-details/biogen-announces-topline-results-tofersen-phase-3-study-and-its', 'title': 'Biogen Announces Topline Results from the Tofersen Phase 3 Study and its Open-Label Extension in SOD1-ALS', 'source': 'Biogen', 'date': 'Oct 17, 2021', 'snippet': 'In the Phase 3 VALOR study, the primary endpoint as measured by the Revised \nAmyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R)...', 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b190b666f1a7778b0ef42a29712444b4194318c7d91f23ab5edb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7961919903755188}","{'position': 3, 'link': 'https://www.nih.gov/news-events/news-releases/next-generation-als-drug-silences-inherited-form-disease-animal-models', 'title': 'Next-generation ALS drug silences inherited form of the disease in animal models', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jul 25, 2018', 'snippet': 'NIH-funded preclinical study suggests drug may be ready for early stage \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b19004a873b6ca0dbc29c5a1be82919c304e8db7df1d1db57434.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9003764986991882}","{'position': 4, 'link': 'https://alsnewstoday.com/news/fda-approves-tofersen-now-qalsody-treatment-adults-sod1-als/', 'title': 'FDA approves tofersen, now Qalsody, as treatment for SOD1-ALS |...', 'source': 'ALS News Today', 'date': 'Apr 25, 2023', 'snippet': ""The US Food and Drug Administration (FDA) has granted conditional approval \nto Biogen's tofersen, now named Qalsody, for the treatment of amyotrophic \nlateral..."", 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b1906ce44b6124b935656da0f469efb877ce0ee308921964ddf6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7133066058158875}","{'position': 5, 'link': 'https://alsnewstoday.com/news/phase-3-tofersen-trial-fails-slow-sod1-als-trends-hopeful-valor-trial/', 'title': 'Tofersen Fails to Slow SOD1-ALS in VALOR Trial, But Hopeful Trends Seen', 'source': 'ALS News Today', 'date': 'Oct 20, 2021', 'snippet': 'Top-line results of Phase 3 VALOR trial show tofersen failed to \nsignificantly slow disease progression in ALS patients with SOD1 mutations.', 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b1906a0b2870503937ad8bc2d1d8c7212f46728bc5c767572cfe.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5634244084358215}","{'position': 6, 'link': 'https://alsnewstoday.com/news/tofersen-to-treat-sod1-als-under-review-for-european-union/', 'title': 'Tofersen to Treat SOD1 ALS Under Review for European Union | EMA Joins FDA in Considering Approval', 'source': 'ALS News Today', 'date': 'Dec 6, 2022', 'snippet': ""The EMA will review Biogen's application for tofersen's approval in \ntreating ALS caused by SOD1 gene 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'title': ""Biogen's Qalsody approved in European Union to treat SOD1-ALS"", 'source': 'ALS News Today', 'date': 'May 31, 2024', 'snippet': 'The European Commission has approved Qalsody to treat ALS patients in the \nEU whose disease is associated with mutations in the SOD1 gene.', 'thumbnail': 'https://serpapi.com/searches/6723f9de4677bf90f1c1a4e6/images/0958658b8385b19097068ef9d2183b7f65c2866a27dedff959a1ea384add98d1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8798172473907471}","{'position': 9, 'link': 'https://alsnewstoday.com/news/panel-favors-tofersen-biomarker-data-mixed-on-efficacy-sod1-als/', 'title': 'Panel favors tofersen biomarker, is mixed on efficacy in SOD1-ALS...', 'source': 'ALS News Today', 'date': 'Mar 24, 2023', 'snippet': 'A FDA committee agrees that changes in NfL levels are reasonably likely to \npredict effectiveness from tofersen in people with SOD1-ALS.', 'thumbnail': 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inhaled glucocorticoid \nplus a fast-acting β2-agonist may be an alternative to conventional...', 'thumbnail': 'https://serpapi.com/searches/6723fd611677932211856f81/images/29875c24c360ebdac9a87a07700ae7a8e5691a4eed22aa1165c78efb02caf690.png', 'sentiment': 'neutral', 'sentiment_prob': 0.877912700176239}",,,,,,,,,,['neutral'],neutral,1 NCT05289037,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-evaluating-second-covid-19-booster-shots-adults', 'title': 'NIH begins clinical trial evaluating second COVID-19 booster shots in adults', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Mar 31, 2022', 'snippet': 'Adults interested in joining this study should visit clinicaltrials.gov and \nsearch identifier NCT05289037 for a list of sites and contacts.', 'thumbnail': 'https://serpapi.com/searches/6723fd6abd7cf00dff1d56d5/images/36b469637751018aa2f30724bfb76677c78bb458dee828573c85b32a49f07d3c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8881411552429199}","{'position': 2, 'link': 'https://www.nature.com/articles/s41591-023-02503-4', 'title': 'Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial', 'source': 'Nature', 'date': 'Aug 28, 2023', 'snippet': 'Our study shows that updated vaccines targeting Beta or Omicron BA.1 \nprovide broadly crossprotective neutralizing antibody responses against \ndiverse SARS-CoV-2...', 'thumbnail': 'https://serpapi.com/searches/6723fd6abd7cf00dff1d56d5/images/36b469637751018ae77b3bcbbc6d26877d3f16db05b677e72867f614b4f776bc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8610926866531372}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00287716,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/pirfenidone-may-be-effective-for-improving-exercise-capacity-dyspnea-in-idiopathic-pulmonary-fibrosis/', 'title': 'Pirfenidone May Be Effective for Improving Exercise Capacity, Dyspnea in Idiopathic Pulmonary Fibrosis', 'source': 'Pulmonology Advisor', 'date': 'Oct 10, 2018', 'snippet': 'When treated with pirfenidone, patients with idiopathic pulmonary fibrosis \nexperienced significant improvements in 6-minute walking distance...', 'thumbnail': 'https://serpapi.com/searches/6723fc69c7d4a1e0188e874a/images/a9c4b25403ea574ebd92c41a5145ec00eb9d7b9d98a56920bb30d12d488191c5.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5335983633995056}",,,,,,,,,,['positive'],positive,1 NCT00129090,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-024-02231-9', 'title': 'Radiotherapy in younger patients with advanced aggressive B-cell lymphoma—long-term results from the phase 3 R-MegaCHOEP trial | Leukemia', 'source': 'Nature', 'date': 'Mar 27, 2024', 'snippet': 'The R-MegaCHOEP trial investigated the use of high-dose chemotherapy and \nrituximab with subsequent autologous stem cell transplantations compared \nto...', 'thumbnail': 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'https://www.empr.com/home/news/fda-approves-21-valent-pneumococcal-conjugate-vaccine-capvaxive/', 'title': 'FDA Approves 21-Valent Pneumococcal Conjugate Vaccine Capvaxive', 'source': 'Medical Professionals Reference', 'date': 'Jun 18, 2024', 'snippet': 'The Food and Drug Administration (FDA) has approved Capvaxive™ (V116; \npneumococcal 21-valent conjugate vaccine) for:.', 'thumbnail': 'https://serpapi.com/searches/6723fc701397ba2adff5771f/images/679fb11da105ce3361f9eb69a92c01352fbf9b3a76846e045844015cdf41f292.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7008212804794312}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04626921,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/01/09/cnm-au8-leads-clinical-gains-rrms-patients-extension-study/', 'title': 'CNM-Au8 leads to clinical gains for RRMS patients in extension study', 'source': 'Multiple Sclerosis News Today', 'date': 'Jan 9, 2024', 'snippet': 'Daily treatment with CNM-Au8 led to visual and cognitive improvements \nsustained for up to about three years in relapsing MS patients,...', 'thumbnail': 'https://serpapi.com/searches/6723fc7872e5c4d03834f6f6/images/7ce5640c17776ba4c21bb2f435bf37b70fe9e03043c42312063fc257453ac70a.png', 'sentiment': 'positive', 'sentiment_prob': 0.8537219762802124}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/04/18/aan-2024-ms-study-long-term-cnm-au8-shows-myelin-nerve-cell-gains/', 'title': 'AAN 2024: In MS study, long-term CNM-Au8 shows myelin, nerve cell gains', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 18, 2024', 'snippet': 'After a year, patients given CNM-Au8 had improvements in vision and data \nsuggested the therapy improved the health of brain nerve fibers.', 'thumbnail': 'https://serpapi.com/searches/6723fc7872e5c4d03834f6f6/images/7ce5640c17776ba4111fe0e28f2557c8116ff28a874bcf1d814d53e1e25acee7.png', 'sentiment': 'positive', 'sentiment_prob': 0.6827456951141357}",,,,,,,,,"['positive', 'positive']",positive,1 NCT01468233,"{'position': 1, 'link': 'https://www.dermatologyadvisor.com/news/adalimumab-reduces-skin-pain-in-hidradenitis-suppurativa/', 'title': 'Adalimumab Reduces Skin Pain in Hidradenitis Suppurativa', 'source': 'Dermatology Advisor', 'date': 'Jun 22, 2018', 'snippet': 'Outcomes were examined in 2 randomized, double-blind, placebo-controlled, \nparallel-group clinical trials: PIONEER I (ClinicalTrials.gov...', 'thumbnail': 'https://serpapi.com/searches/6723fc84be1497ff0398eb1c/images/3bd1ec65a22f53e9be90074057ce823d190bf5c79e2658b4536e88e4ca15836c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.767997682094574}",,,,,,,,,,['neutral'],neutral,1 NCT01304524,"{'position': 1, 'link': 'https://cervicalcancernews.com/2017/02/15/inovio-and-apollobio-to-collaborate-on-development-and-commercialization-of-hpv-pre-cancer-immunotherapy-vgx-3100-in-greater-china/', 'title': 'HPV Vaccine for China, Taiwan to be Jointly Developed by Inovio, ApolloBio', 'source': 'Cervical cancer News', 'date': 'Feb 15, 2017', 'snippet': ""ApolloBio now has the exclusive right to develop and commercialize Inovio' \nsDNA immunotherapy product, VGX-3100, in China and Taiwan."", 'thumbnail': 'https://serpapi.com/searches/6723fcb1c97e35f1e2a60cbc/images/43e3294c6b3a2207270b109c2fbec930d45df9bf2b382873465d0c63d04187eb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8801657557487488}","{'position': 2, 'link': 'https://cervicalcancernews.com/2017/04/26/inovio-starts-phase-2-trial-of-vgx-3100-vaccine-for-pre-cancerous-vulvar-lesions/', 'title': 'Inovio Starts Phase 2 Trial of VGX-3100 Vaccine for Pre-cancerous Vulvar Lesions', 'source': 'Cervical cancer News', 'date': 'Apr 26, 2017', 'snippet': ""Inovio's Phase 2 trial assessing the effectiveness of VGX-3100 in patients \nwith pre-cancerous lesions of the vulva, or vulvar intraepithelial \nneoplasia (VIN),..."", 'thumbnail': 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'https://www.researchgate.net/publication/382334364_PBPK-led_assessment_of_antimalarial_drugs_as_candidates_for_Covid-19_Simulating_concentrations_at_the_site_of_action_to_inform_repurposing_strategies', 'title': 'for Covid- 19: Simulating concentrations at the site of action', 'source': 'ResearchGate', 'date': 'Jul 26, 2024', 'snippet': 'PDF | The urgent need for safe, efficacious, and accessible drug treatments \nto treat coronavirus disease 2019 (COVID‐19) prompted a global...', 'thumbnail': 'https://serpapi.com/searches/6723fd29cc48795386827179/images/870e4c8258b2b1d8aa32ab19feabd9e3f366231011e8088fa107f653748419b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8669917583465576}",,,,,,,,,,['neutral'],neutral,1 NCT04476043,"{'position': 1, 'link': 'https://www.termedia.pl/Hidradenitis-suppurativa-a-new-therapeutic-approach-for-an-old-disease,7,54608,1,1.html', 'title': 'Hidradenitis suppurativa: a new therapeutic approach for an old disease', 'source': 'Termedia', 'date': 'Aug 12, 2024', 'snippet': 'Hidradenitis suppurativa (HS) is a chronic inflammatory disease \ncharacterised by recurrent painful nodules, abscesses, fistulas and \nscarring...', 'thumbnail': 'https://serpapi.com/searches/6723fd382b5fa77e1b8859f2/images/ae7f86628ea705746d356cfd6a27a3c4f7eb4b41eaaf8bac798d944fcd7512da.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6704685091972351}",,,,,,,,,,['negative'],negative,0 NCT05355805,"{'position': 1, 'link': 'https://www.termedia.pl/Hidradenitis-suppurativa-a-new-therapeutic-approach-for-an-old-disease,7,54608,1,1.html', 'title': 'Hidradenitis suppurativa: a new therapeutic approach for an old disease', 'source': 'Termedia', 'date': 'Aug 12, 2024', 'snippet': 'Hidradenitis suppurativa (HS) is a chronic inflammatory disease \ncharacterised by recurrent painful nodules, abscesses, fistulas and \nscarring...', 'thumbnail': 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'title': 'SHINE Study: Ibrutinib Plus Bendamustine and Rituximab in Elderly Patients With MCL', 'source': 'OncLive', 'date': 'Jan 31, 2023', 'snippet': 'Transcript: Alexey V. Danilov, MD, PhD: We just discussed the TRIANGLE \nstudy [NCT02858258], which enrolled younger patients with mantle cell...', 'thumbnail': 'https://serpapi.com/searches/6723fce5361fd42d611f4508/images/86afae91f82bbf2e0e2ecfc1afec3e502012d281646de8694d3d1f5b8652aef2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8881753087043762}","{'position': 3, 'link': 'https://www.clinicalleader.com/doc/new-fda-guidance-clinical-trial-considerations-to-support-accelerated-approval-of-oncology-therapeutics-0001', 'title': 'New FDA Guidance Clinical Trial Considerations To Support Accelerated Approval Of Oncology Therapeutics', 'source': 'Clinical Leader', 'date': 'Apr 21, 2023', 'snippet': 'On April 6, 2023, AbbVie announced that it was voluntarily withdrawing \nibrutinib, which was granted accelerated approval for two...', 'thumbnail': 'https://serpapi.com/searches/6723fce5361fd42d611f4508/images/86afae91f82bbf2e7fc51bcfa6d508fad048c4d977023f7e5bbb8dc1f93f97fd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8708025217056274}","{'position': 4, 'link': 'https://ascopost.com/news/april-2023/update-on-withdrawal-of-ibrutinib-accelerated-approvals-for-mcl-and-mzl-in-the-united-states/', 'title': 'Update on Withdrawal of Ibrutinib Accelerated Approvals for MCL and MZL in the United States', 'source': 'The ASCO Post', 'date': 'Apr 12, 2023', 'snippet': 'AbbVie announced that it intends to voluntarily withdraw, in the United \nStates, accelerated ibrutinib (Imbruvica) approvals for patients with \nmantle cell...', 'thumbnail': 'https://serpapi.com/searches/6723fce5361fd42d611f4508/images/86afae91f82bbf2e8e7692eac69f6b3f26f84dc0eb8718371a02ce5c562a99c7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9219139218330383}","{'position': 5, 'link': 'https://www.cancertherapyadvisor.com/news/imbruvica-no-longer-approved-to-treat-mcl-mzl/', 'title': 'Imbruvica No Longer Approved to Treat MCL, MZL in the US', 'source': 'Cancer Therapy Advisor', 'date': 'Apr 12, 2023', 'snippet': 'Janssen and AbbVie are withdrawing the accelerated approvals of Imbruvica \n(ibrutinib) for mantle cell lymphoma (MCL) and marginal zone lymphoma (MZL)', 'thumbnail': 'https://serpapi.com/searches/6723fce5361fd42d611f4508/images/86afae91f82bbf2ee1ba7335a483e5d56fb66cdef29b4823df95ff209dc408a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.501125693321228}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT02419287,"{'position': 1, 'link': 'https://www.science.org/doi/10.1126/scitranslmed.abo3826', 'title': 'Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma', 'source': 'Science | AAAS', 'date': 'Jun 28, 2023', 'snippet': 'Blockade of PI3Kγ or CCR7 signaling together with ALK TKI treatment reduces \nprimary resistance and the survival of persister lymphoma cells in ALCL.', 'thumbnail': 'https://serpapi.com/searches/6723fcf46aa3647845dbdebc/images/d91c8bd0b3d3178bc8b9503ce531f357bc3261ae386dc16f4af05c63aabf10db.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7612215280532837}",,,,,,,,,,['neutral'],neutral,1 NCT02734160,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0246-z', 'title': 'Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer', 'source': 'Nature', 'date': 'Oct 15, 2018', 'snippet': 'Galunisertib is the first-in-class, first-in-human, oral small-molecule \ntype I transforming growth factor-beta receptor (ALK5)...', 'thumbnail': 'https://serpapi.com/searches/6723fcf67ac731b61c940814/images/2650686842ad26b996d501dbffd59b341d76cc173530397c53e243b8198d4cef.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8163897395133972}",,,,,,,,,,['neutral'],neutral,1 NCT02825940,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanwpc/article/PIIS2666-6065(22)00232-2/fulltext', 'title': 'Efficacy and safety of KL-A167 in previously treated recurrent or metastatic nasopharyngeal carcinoma: a multicenter, single-arm, phase 2 study', 'source': 'The Lancet', 'date': 'Oct 10, 2022', 'snippet': 'KL-A167 is a fully humanized monoclonal antibody targeting programmed cell \ndeath-ligand 1. This phase 2 study aimed to evaluate the efficacy...', 'thumbnail': 'https://serpapi.com/searches/6723fcf854605c248370e78e/images/35d3b0725001ffaef7217f909c2337dca9cab20dcdf88b6e59caf951756dbd21.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9025993943214417}",,,,,,,,,,['neutral'],neutral,1 NCT04076943,"{'position': 1, 'link': 'https://www.onclive.com/view/chinese-phase-3-trial-of-roxadustat-in-non-myeloid-malignancies-meets-primary-end-point', 'title': 'Chinese Phase 3 Trial of Roxadustat in Non-Myeloid Malignancies Meets Primary End Point', 'source': 'OncLive', 'date': 'May 18, 2023', 'snippet': 'Roxadustat proved to be noninferior to recombinant erythropoietin alfa with \nregard to change in hemoglobin level from baseline to an average...', 'thumbnail': 'https://serpapi.com/searches/6723fd177d533e68053dccdb/images/f11e777649455d2ca83de5fda4a886a5f27209e713f0a418da348d21260e7fa6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8067212104797363}",,,,,,,,,,['neutral'],neutral,1 NCT02472145,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-020-0773-5', 'title': 'Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study', 'source': 'Nature', 'date': 'Mar 16, 2020', 'snippet': 'Talacotuzumab, a humanized anti-CD123 monoclonal antibody, was evaluated in \ncombination with decitabine in elderly patients with acute myeloid leukemia \n(AML)...', 'thumbnail': 'https://serpapi.com/searches/6723fd1ed910393e41a1aeea/images/ad934a64aab9da3c12189490bc14c149f6a3dd014c78955cdf25927200f9b61d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.857531726360321}",,,,,,,,,,['neutral'],neutral,1 NCT03393520,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/avp-786-fails-ease-alzheimers-related-agitation-phase-3-trial/', 'title': 'AVP-786 fails to ease Alzheimer’s-related agitation in Phase 3 trial', 'source': ""Alzheimer's News Today"", 'date': 'Feb 29, 2024', 'snippet': ""A Phase 3 clinical trial of AVP-786 failed to meet its main goal of easing \nagitation in adults with dementia due to Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/6723fd97213c87df4d44ac84/images/65ed674586a620c84ef2537bfdd0a19dcd1552513cb6cca4776dcf3f9c02d0fe.png', 'sentiment': 'negative', 'sentiment_prob': 0.8483138084411621}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20240522034559/en/Otsuka-to-Terminate-Development-of-AVP-786', 'title': 'Otsuka to Terminate Development of AVP-786', 'source': 'Business Wire', 'date': 'May 22, 2024', 'snippet': 'Otsuka Pharmaceutical Development & Commercialization, Inc. (OPDC) announce \ntermination of development of the novel compound AVP-786.', 'thumbnail': 'https://serpapi.com/searches/6723fd97213c87df4d44ac84/images/65ed674586a620c81fceb611c4469460cf02eaf387ce41cbf706c0f4e04bda60.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7247691750526428}","{'position': 3, 'link': 'https://www.neurologylive.com/view/nd0612-receives-complete-letter-response-otsuka-terminates-avp-786-tsha-102-performs-phase-1-2-reveal-studies', 'title': 'ND0612 Receives Complete Letter Response, Otsuka Terminates AVP-786, TSHA-102 Performs in Phase 1/2 REVEAL Studies', 'source': 'Neurology live', 'date': 'Jun 23, 2024', 'snippet': 'Neurology News Network. for the week ending June 22, 2024. [WATCH TIME: 4 \nminutes]', 'thumbnail': 'https://serpapi.com/searches/6723fd97213c87df4d44ac84/images/65ed674586a620c8f09bb0e9f8ed9a42269599c1eadd078221dd5bae111e4965.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9419007897377014}","{'position': 4, 'link': 'https://alzheimersnewstoday.com/news/otsuka-stops-development-avp-786-agitation-alzheimers/', 'title': 'Otsuka stops developing AVP-786 therapy for Alzheimer’s agitation', 'source': ""Alzheimer's News Today"", 'date': 'May 23, 2024', 'snippet': ""Otsuka is stopping the development of AVP-786, its experimental therapy to \ntreat agitation in people with Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/6723fd97213c87df4d44ac84/images/65ed674586a620c8961cd60e6994df9ac462d546f121db90087410ceaa0e4c57.png', 'sentiment': 'negative', 'sentiment_prob': 0.7110889554023743}",,,,,,,"['negative', 'neutral', 'neutral', 'negative']",negative,0 NCT01854034,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-019-0038-9', 'title': 'Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Mar 8, 2019', 'snippet': 'Inframe insertions of three or more base pairs in exon 20 of the epidermal \ngrowth factor receptor (EGFR) gene were among the first EGFR...', 'thumbnail': 'https://serpapi.com/searches/6723fda151d84d4f569b65a3/images/d3e8d992a3232d0eb86cdbc9c03f3ac7473254d3230367578947a5605c16b6d5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8813299536705017}",,,,,,,,,,['neutral'],neutral,1 NCT00600249,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-021-00334-5', 'title': 'Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies', 'source': 'Nature', 'date': 'Sep 17, 2021', 'snippet': 'Our results indicate that high expression of cell cycle genes, combined \nwith cold immunological phenotype, may predict strong TNBC resistance to \nNAT and rapid...', 'thumbnail': 'https://serpapi.com/searches/6723fdaad9c3e68834f91862/images/b755d43add6d4199d85a6c855c2de3deae9b05b1033a336ac4cec7496cd16101.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8336379528045654}",,,,,,,,,,['neutral'],neutral,1 NCT03263429,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/61/supplement_1/630', 'title': 'PET imaging of glutamine metabolism in a clinical trial of metastatic colorectal cancer', 'source': 'Journal of Nuclear Medicine', 'date': 'May 1, 2020', 'snippet': 'Allison Cohen, Adria Payne, Gary Smith, Jennifer Whisenant, Todd Peterson, \nKristen Ciombor, Dana Cardin, Cathy Eng, Laura Goff, Satya Das,...', 'thumbnail': 'https://serpapi.com/searches/6723fdc0a505f777dd204287/images/116330fb6a70ec93236f60df07f6c7219cdfcfb1e0bb23c434aab395fcc63de8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9362392425537109}",,,,,,,,,,['neutral'],neutral,1 NCT03298087,"{'position': 1, 'link': 'https://www.urologytimes.com/view/dr-nickols-on-phase-2-solar-trial-of-multimodal-therapy-in-prostate-cancer', 'title': 'Dr. Nickols on phase 2 SOLAR trial of multimodal therapy in prostate cancer', 'source': 'Urology Times', 'date': '1 month ago', 'snippet': 'In this video, Nicholas G. Nickols, MD, PhD, highlights the background and \ninitial findings from the phase 2 SOLAR trial (NCT03298087).', 'thumbnail': 'https://serpapi.com/searches/6723fde6922cceedec28834c/images/89bfb8b05af48ef4837db41a76beea2cde381307ab8a94c58cad3aafda3ed383.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9172107577323914}",,,,,,,,,,['neutral'],neutral,1 NCT02783482,"{'position': 1, 'link': 'https://www.biospace.com/gc-biopharma-announces-us-fda-approval-for-alyglo-immune-globulin-intravenous-human-stwk-10-percent-liquid-for-adults-with-primary-humoral-immunodeficiency-pi', 'title': 'GC Biopharma Announces US FDA Approval for ALYGLO™ (Immune Globulin Intravenous, Human-stwk) 10% Liquid for Adults with Primary Humoral Immunodeficiency (PI)', 'source': 'BioSpace', 'date': 'Dec 17, 2023', 'snippet': 'The US Food and Drug Administration has approved ALYGLO 10% Liquid, \nformerly referred to as “GC5107,” for the treatment of adult patients aged \n17 years and...', 'thumbnail': 'https://serpapi.com/searches/6723fdfbea57e958c5952254/images/b5c9a4eb7f0774495ff9e25f81357028298a551bb51e0ac94a25c7a201897b11.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8150995969772339}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/investigational-ivig-product-under-review-for-primary-immunodeficiency/', 'title': 'Investigational IVIG Product Under Review for Primary Immunodeficiency', 'source': 'Medical Professionals Reference', 'date': 'Jul 31, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted the resubmitted \nBiologics License Application (BLA) for GC5107B (immune globulin \nintravenous [human])', 'thumbnail': 'https://serpapi.com/searches/6723fdfbea57e958c5952254/images/b5c9a4eb7f077449b27c3e562fe5ed7f11557a3fc467dff02852b94e1567f000.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.911652147769928}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00028990,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa072113', 'title': 'Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Mar 27, 2016', 'snippet': 'In an open-label, randomized, phase 3 trial, we compared the efficacy and \nsafety of paclitaxel with that of paclitaxel plus bevacizumab, a \nmonoclonal...', 'thumbnail': 'https://serpapi.com/searches/6723fe2ef410441876f4f6ba/images/076044cc4a6e0e07a1be658447148d6c160d0f387a0a9e5a0b2e4639419eae7b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8797870874404907}",,,,,,,,,,['neutral'],neutral,1 NCT03777059,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2035908', 'title': 'Atogepant for the Preventive Treatment of Migraine', 'source': 'The New England Journal of Medicine', 'date': 'Aug 24, 2021', 'snippet': 'Oral atogepant once daily was effective in reducing the number of migraine \ndays and headache days over a period of 12 weeks. Adverse events included...', 'thumbnail': 'https://serpapi.com/searches/6723fe3471c62b8d36d24d58/images/3761f74dc5cfc8c5a11c9e6fd6be8f0c6fac14f8f42953ffdd5071c3b86f9d40.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7206376194953918}",,,,,,,,,,['neutral'],neutral,1 NCT01397461,"{'position': 1, 'link': 'https://www.infectiousdiseaseadvisor.com/home/topics/skin-infections/topical-antibacterial-agent-effective-for-treatment-of-impetigo/', 'title': 'Topical Antibacterial Agent Effective for Treatment of Impetigo', 'source': 'Infectious Disease Advisor', 'date': 'Dec 3, 2018', 'snippet': 'Topical ozenoxacin 1% cream is a rapid and effective treatment for patients \nwith impetigo. The agent demonstrates consistent clinical and bacteriologic \neffects.', 'thumbnail': 'https://serpapi.com/searches/6723fe460664c983dca14474/images/3cbdc4b145921ea9cec1337d4aecf9577b638f0b2c6a228666898a34d11a21cd.png', 'sentiment': 'positive', 'sentiment_prob': 0.7753939628601074}",,,,,,,,,,['positive'],positive,1 NCT01110486,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0020-2', 'title': 'Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial', 'source': 'Nature', 'date': 'Mar 19, 2018', 'snippet': 'Ilorasertib (ABT-348) inhibits Aurora and VEGF receptor (VEGFR) kinases. \nPatients with advanced solid tumours participated in a phase 1 \ndose-escalation trial.', 'thumbnail': 'https://serpapi.com/searches/6723fe508cf8aebaab22c641/images/916a27025804ba00342d9472676cff814a44c3daa172680e1045371ee2143d92.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9103592038154602}",,,,,,,,,,['neutral'],neutral,1 NCT05247489,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2118828', 'title': 'Two Phase 3, Randomized, Controlled Trials of Ruxolitinib Cream for Vitiligo', 'source': 'The New England Journal of Medicine', 'date': 'Oct 19, 2022', 'snippet': 'Vitiligo is a chronic autoimmune disease that causes skin depigmentation. A \ncream formulation of ruxolitinib (an inhibitor of Janus kinase 1...', 'thumbnail': 'https://serpapi.com/searches/6723fe6917b10eb87f490a11/images/a8e2ce6910b1b97a687a50c8adefbb26dbdd2d719219958bcc25d65e69545738.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6550623774528503}",,,,,,,,,,['neutral'],neutral,1 NCT05310422,"{'position': 1, 'link': 'https://www.cgtlive.com/view/sylentis-sirna-therapy-fails-to-improve-symptoms-dry-eye-disease-sjogren', 'title': 'Sylentis’ siRNA Therapy Fails to Improve Symptoms of Dry Eye Disease Due to Sjögren’s Syndrome', 'source': 'CGTLive®', 'date': 'Feb 13, 2024', 'snippet': ""Sylentis' phase 3 clinical trial (NCT04819269) of tivanisiran RNA therapy \nhas failed the primary endpoint of improving dry eye symptoms associated \nwith Sjögren..."", 'thumbnail': 'https://serpapi.com/searches/6723fe7b9936882cb5f0ccd2/images/a65f169b6229d0002a2ec0f1edaca4dc8a07ee43723daf5e26453e13dc220263.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8161905407905579}",,,,,,,,,,['negative'],negative,0 NCT05005845,"{'position': 1, 'link': 'https://www.science.org/doi/10.1126/sciadv.adk4946', 'title': 'Effect of NFX-179 MEK inhibitor on cutaneous neurofibromas in persons with neurofibromatosis type 1', 'source': 'Science | AAAS', 'date': 'May 1, 2024', 'snippet': 'This phase 2a trial investigated the efficacy of NFX-179 Topical Gel, a \nmetabolically labile MEK inhibitor, in the treatment of cutaneous \nneurofibromas (cNFs)...', 'thumbnail': 'https://serpapi.com/searches/6723fea2d771bdf6b3351eb4/images/5e50ffe4c5a0e68b891b3e37143598f30146fb867fd34eb9cc430b26eb615953.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8717843294143677}",,,,,,,,,,['neutral'],neutral,1 NCT04722003,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0264410X23000865', 'title': 'Vaccine value profile for Neisseria gonorrhoeae', 'source': 'ScienceDirect.com', 'date': 'Jul 25, 2024', 'snippet': 'This vaccine value profile (VVP) provides a high level, holistic assessment \nof the current data to inform the potential public health, economic and \nsocietal...', 'thumbnail': 'https://serpapi.com/searches/6723feaed0253e3d8bb51033/images/28a3f363ded8cb2956fb33587245303c5083959d0ff30fbe01fea2e0e23a8bd5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8531647324562073}",,,,,,,,,,['neutral'],neutral,1 NCT00856492,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-023-00535-0', 'title': 'Image analysis-based tumor infiltrating lymphocytes measurement predicts breast cancer pathologic complete response in SWOG S0800 neoadjuvant chemotherapy trial | npj Breast Cancer', 'source': 'Nature', 'date': 'May 13, 2023', 'snippet': 'We assessed the predictive value of an image analysis-based \ntumor-infiltrating lymphocytes (TILs) score for pathologic complete \nresponse (pCR) and event-free...', 'thumbnail': 'https://serpapi.com/searches/6723feb254163de3afe419a5/images/457a83cf4ba856622e3ee5729e8bfc520f32afc90550c6467c46ed3ee9262807.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8688086271286011}",,,,,,,,,,['neutral'],neutral,1 NCT02445794,"{'position': 1, 'link': 'https://friedreichsataxianews.com/news/retrotope-gives-fda-the-design-of-a-pivotal-trial-for-its-friedreichs-ataxia-therapy/', 'title': ""Friedreich's Ataxia Therapy Maker Retrotope Submits Pivotal-Trial Design to FDA"", 'source': ""Friedreich's Ataxia News"", 'date': 'Apr 19, 2018', 'snippet': ""Read about Retrotope submitting the design of a pivotal clinical trial for \nits Friedreich's ataxia therapy RT001 to the U.S. Food and Drug..."", 'thumbnail': 'https://serpapi.com/searches/6723feb77a12fd60490b6cab/images/d365ba4631026cba3cec423bc50b9b8769fb81caba62fd75dea75c564930939f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8871482014656067}",,,,,,,,,,['neutral'],neutral,1 NCT03529175,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02170-9', 'title': 'Clinical and biological markers predictive of treatment response associated with metastatic pancreatic adenocarcinoma', 'source': 'Nature', 'date': 'Feb 22, 2023', 'snippet': 'Readily measurable patient variables can aid the prediction of outcomes \nfrom combination chemotherapy used to treat metastatic PDAC.', 'thumbnail': 'https://serpapi.com/searches/6723febd72f7163db9b6fd20/images/a1ff6ea3375d898a2ebb919238581a7ef806e49f7cea850f385fc18415504e52.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8889390826225281}",,,,,,,,,,['neutral'],neutral,1 NCT04539262,"{'position': 1, 'link': 'https://www.nature.com/articles/s41564-023-01356-4', 'title': 'Therapeutics for COVID-19', 'source': 'Nature', 'date': 'May 4, 2023', 'snippet': 'Vaccines and monoclonal antibody treatments to prevent severe coronavirus \ndisease 2019 (COVID-19) illness were available within a year of the \npandemic being...', 'thumbnail': 'https://serpapi.com/searches/6723fec0bcd65222896571e3/images/f3ecaa2ee672d813e2de1d633078f5516967bff06ca652a7001a5adf10006584.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7230387330055237}",,,,,,,,,,['neutral'],neutral,1 NCT06105528,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2024/10/30/2971622/0/en/ProMIS-Neurosciences-Presents-Positive-Data-from-PMN310-Phase1a-Clinical-Trial-at-the-17th-Clinical-Trials-on-Alzheimer-s-Disease-Conference.html', 'title': 'ProMIS Neurosciences Presents Positive Data from PMN310', 'source': 'GlobeNewswire', 'date': '1 day ago', 'snippet': 'Results indicated PMN310 was generally well-tolerated and monthly dosing \ncan provide CSF levels adequate for target engagement Initiation of...', 'thumbnail': 'https://serpapi.com/searches/6723fec9f60b6f8f33efe041/images/86a088210923e6946ec1c7715f06a0112603cdd9582892b89be78c5875796fd7.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8455473780632019}","{'position': 2, 'link': 'https://www.globenewswire.com/news-release/2024/04/01/2855463/0/en/ProMIS-Neurosciences-Announces-Full-Year-2023-Financial-Results-and-Recent-Highlights.html', 'title': 'ProMIS Neurosciences Announces Full Year 2023 Financial Results and Recent Highlights', 'source': 'GlobeNewswire', 'date': 'Apr 1, 2024', 'snippet': ""Top-line data from first-in-human Phase 1a clinical trial of PMN310 as a \ntreatment for Alzheimer's disease on track for mid-2024..."", 'thumbnail': 'https://serpapi.com/searches/6723fec9f60b6f8f33efe041/images/86a088210923e694f7c2bcd5defcefd5c419f3f79d1f7c2b1970855205cc36b7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8202195167541504}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT04380701,"{'position': 1, 'link': 'https://www.nature.com/articles/s41586-020-2814-7', 'title': 'COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses', 'source': 'Nature', 'date': 'Sep 30, 2020', 'snippet': 'Here we present antibody and T cell responses after vaccination with \nBNT162b1 from a second, non-randomized open-label phase I/II trial in \nhealthy adults.', 'thumbnail': 'https://serpapi.com/searches/6723fedac05eb54546b6878e/images/1fe91fc51711fc830c24b739a1bdf6f77aa2e55e9e48249e2c018c310115e614.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9030770063400269}","{'position': 2, 'link': 'https://www.nature.com/articles/s41586-021-03653-6', 'title': 'BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans', 'source': 'Nature', 'date': 'May 27, 2021', 'snippet': 'BNT162b2, a nucleoside-modified mRNA formulated in lipid nanoparticles that \nencodes the SARS-CoV-2 spike glycoprotein (S) stabilized in its...', 'thumbnail': 'https://serpapi.com/searches/6723fedac05eb54546b6878e/images/1fe91fc51711fc839a3d36eebc51a3d671c51bf71a5000d85c2ee5b1607776dd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8637851476669312}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05412004,"{'position': 1, 'link': 'https://www.appliedclinicaltrialsonline.com/view/tirzepatide-shows-significant-reduction-in-severity-of-obstructive-sleep-apnea-in-patients-with-obesity', 'title': 'Tirzepatide Shows Significant Reduction in Severity of Obstructive Sleep Apnea in Patients with Obesity', 'source': 'Applied Clinical Trials', 'date': 'Apr 17, 2024', 'snippet': ""Findings from the Phase III SURMOUNT-OSA (NCT05412004) clinical trial \ndemonstrated the efficacy of Eli Lilly's tirzepatide in lowering the..."", 'thumbnail': 'https://serpapi.com/searches/6723fee624296a895db7aa07/images/3b2407b4d46c491b51360c828df2019569dcb9415e17179f051c767d4d5c96f3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5443980693817139}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/tirzepatide-reduced-sleep-apnea-severity-by-up-to-nearly-two-thirds-in-adults-with-obstructive-sleep-apnea-osa-and-obesity-302118929.html', 'title': 'Tirzepatide reduced sleep apnea severity by up to nearly two-thirds in adults with obstructive sleep apnea (OSA) and obesity', 'source': 'PR Newswire', 'date': 'Apr 17, 2024', 'snippet': 'PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced positive \ntopline results of the SURMOUNT-OSA phase 3 clinical trials that...', 'thumbnail': 'https://serpapi.com/searches/6723fee624296a895db7aa07/images/3b2407b4d46c491b8f86e204ac04d3b9eaec6c18a2453599cbf63ecd577ffe29.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.62837815284729}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03093259,"{'position': 1, 'link': 'https://ibdnewstoday.com/2020/12/21/abivax-completes-enrollment-for-phase-2b-trial-testing-abx464-for-moderate-to-severe-ulcerative-colitis-uc/', 'title': 'Abivax Completes Enrollment in ABX464 Trial for Ulcerative Colitis', 'source': 'IBD News Today', 'date': 'Dec 21, 2020', 'snippet': 'Abivax completed patient enrollment ahead of schedule for a trial testing \nABX464 for people with moderate to severe ulcerative colitis.', 'thumbnail': 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in the brains of people with Parkinson's \ndisease and..."", 'thumbnail': 'https://serpapi.com/searches/6724017f98721799073fefe4/images/4ba0231e34725232716bc098eb7b42316d235c42722b32ebe4cde91b4aa3c389.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6706705689430237}",,,,,,,,,,['neutral'],neutral,1 NCT04759131,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/fda-approves-updated-altuviiio-label-full-xtend-kids-data/', 'title': 'FDA approves updated Altuviiio label with full XTEND-Kids data', 'source': 'Hemophilia News Today', 'date': '١٥\u200f/٠٥\u200f/٢٠٢٤', 'snippet': 'The US Food and Drug Administration (FDA) has approved an update to the \nprescribing information for Altuviiio (efanesoctocog alfa), a long-lasting \nfactor VIII...', 'thumbnail': 'https://serpapi.com/searches/6724018d9062f85c40db7784/images/5a81247f7a62540b4407702878486b38fcb823ba0aaade122643327e07fbebed.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7442442774772644}","{'position': 2, 'link': 'https://www.contemporarypediatrics.com/view/fda-approves-altuviiio-updated-label-for-bleed-protection-in-children-with-hemophilia-a', 'title': 'FDA approves ALTUVIIIO updated label for bleed protection in children with hemophilia', 'source': 'Contemporary Pediatrics', 'date': '١٣\u200f/٠٥\u200f/٢٠٢٤', 'snippet': 'The extended label approval is based on full evidence from the XTEND-Kids \nstudy.', 'thumbnail': 'https://serpapi.com/searches/6724018d9062f85c40db7784/images/5a81247f7a62540b62d7a3ba3ae11ee40ac2fef0a8503b697cebd749d28ccf09.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8187620043754578}","{'position': 3, 'link': 'https://www.hematologyadvisor.com/news/hemophilia-efanesoctocog-alfa-prevent-inhibitor-development-treatment-risk/', 'title': 'Efanesoctocog Alfa Appears to Prevent Inhibitor Development, Reduce Bleeding in Children With Severe Hemophilia A', 'source': 'Hematology Advisor', 'date': '١٧\u200f/٠٧\u200f/٢٠٢٣', 'snippet': 'The phase 3 XTEND-Kids study met its primary endpoint, with no inhibitor \ndevelopment seen with treatment in children with severe hemophilia...', 'thumbnail': 'https://serpapi.com/searches/6724018d9062f85c40db7784/images/5a81247f7a62540bf79ce1f742df542351a517458a66237fe88a5e6d2bc78661.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8442665338516235}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04775953,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00104-2/fulltext', 'title': 'European society of clinical microbiology and infectious diseases (ESCMID) global 2024', 'source': 'The Lancet', 'date': 'May 20, 2024', 'snippet': 'The 34th Congress of the European Society of Clinical Microbiology and \nInfectious Diseases (ESCMID Global) took place in Barcelona under its new \nbrand name.', 'thumbnail': 'https://serpapi.com/searches/672404210c08f201ce46d9dc/images/d5c2da71310326a82cf48b7885a75236c442b4609aa8d8102cbf9e65c7bc358b.jpeg', 'sentiment': 'neutral', 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infection and...', 'source': 'ResearchGate', 'date': 'Sep 8, 2018', 'snippet': 'γδ T cells undergo massive expansion in the peripheral blood of renal \ntransplant recipients who are infected with cytomegalovirus (CMV).', 'thumbnail': 'https://serpapi.com/searches/672404346aa364780f49ce38/images/b584755660f5511b996e2b39c59eba779a9c0d870c7e6790f94e27007df6fa75.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5117400884628296}",,,,,,,,,,['neutral'],neutral,1 NCT05584657,"{'position': 1, 'link': 'https://www.drugtopics.com/view/fda-approves-sulopenem-etzadroxil-and-probenecid-for-uncomplicated-urinary-tract-infections', 'title': 'FDA Approves Sulopenem Etzadroxil and Probenecid for Uncomplicated UTIs', 'source': 'Drug Topics', 'date': '6 days ago', 'snippet': 'The FDA has approved just the second treatment for uncomplicated urinary \ntract infections (UTIs) in the last 2 decades.', 'thumbnail': 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Oral Sulopenem (Orlynvah) for Uncomplicated Urinary Tract Infections', 'source': 'Contagion Live', 'date': '2 days ago', 'snippet': 'Iterum Therapeutics receives approval for Orlynvah as the first oral penem \nfor treating uncomplicated urinary tract infections in adult...', 'thumbnail': 'https://serpapi.com/searches/67240436d0c9837151d48334/images/accd70f36f4fbd57a16d2991217bc34b2178f1338683fa294bc2c0684f2dfd1b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8403930068016052}","{'position': 4, 'link': 'https://www.urologytimes.com/view/live-updates-from-fda-advisory-committee-meeting-on-oral-sulopenem-for-uuti', 'title': 'FDA Advisory Committee meets to discuss NDA of oral sulopenem for uUTI', 'source': 'Urology Times', 'date': '1 month ago', 'snippet': ""Follow Urology Times' coverage of the full-day FDA advisory committee \nmeeting regarding Iterum Therapeutics' new drug application for oral..."", 'thumbnail': 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'snippet': 'mRESVIA is the first mRNA vaccine approved for a disease other than \nCOVID-19.', 'thumbnail': 'https://serpapi.com/searches/67240436d0c9837151d48334/images/accd70f36f4fbd5719a0b3350ad6a81a73a4839461d70c8b1dfd4839276f556d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6358482241630554}","{'position': 7, 'link': 'https://www.drugtopics.com/view/fda-roundup-agency-highlights-from-june-2024', 'title': 'FDA Roundup: Agency Highlights From June 2024', 'source': 'Drug Topics', 'date': 'Jun 28, 2024', 'snippet': 'The FDA approved ensifentrine (Ohtuvayre) for the maintenance treatment of \nchronic obstructive pulmonary disease (COPD) in adult patients,...', 'thumbnail': 'https://serpapi.com/searches/67240436d0c9837151d48334/images/accd70f36f4fbd575ba2477048bbfd2d9bfc300b99ab86969b153921e8695b7d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8896152973175049}","{'position': 8, 'link': 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\napproved by the FDA in May and will have a whole acquisition cost of...', 'thumbnail': 'https://serpapi.com/searches/67240436d0c9837151d48334/images/accd70f36f4fbd5769f117d9063adb566ea046d2a251ca904c262a91ce7ffb69.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8044151663780212}","{'position': 10, 'link': 'https://www.drugtopics.com/view/rsv-poses-more-danger-to-older-adults-than-covid-19-flu', 'title': 'RSV Poses More Danger to Older Adults Than COVID-19, Flu', 'source': 'Drug Topics', 'date': 'Oct 11, 2023', 'snippet': 'A new study found that more patients hospitalized with RSV needed standard \nflow oxygen, HFNC, NIV, and ICU admission than the patients with...', 'thumbnail': 'https://serpapi.com/searches/67240436d0c9837151d48334/images/accd70f36f4fbd57510aacd24ab38748fe31656c140db58f03d124cc82657de0.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5299963355064392}","['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'negative', 'neutral', 'negative']",neutral,1 NCT01791595,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-0727-8', 'title': 'A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965 | British Journal of Cancer', 'source': 'Nature', 'date': 'Feb 20, 2020', 'snippet': 'A 47-year-old man with metastatic melanoma presented with refractory \nhyperlactaemic acidosis following the first dose of the...', 'thumbnail': 'https://serpapi.com/searches/672403e0fd3b5ae5d2b98a7c/images/d05734b348a4ad07cdec90d7d5b055436420abd9713dd00c9c37d0bc81567919.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6695555448532104}",,,,,,,,,,['neutral'],neutral,1 NCT01274182,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/granulomatosis-with-polyangiitis-and-microscopic-polyangiitis-patients-can-use-mabthera-biosimilar-rixathon-following-ec-approval/', 'title': 'EC Approves MabThera Biosimilar Rixathon for 2 AAV Disorders', 'source': 'ANCA Vasculitis News', 'date': 'Jul 14, 2017', 'snippet': ""The EC has approved the use and marketing of Sandoz's Mabthera biosimilar \ndrug Rixathon for the treatment of blood cancers and immunological..."", 'thumbnail': 'https://serpapi.com/searches/672403e093584c2b3cbbfa07/images/f5794a3bd80a9affc2737edc8e62225770abc2d0ef7b7734d850ed308995d1ae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8589828014373779}",,,,,,,,,,['neutral'],neutral,1 NCT02292758,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.756214/full', 'title': 'Efficacy and Safety of Systemic Treatments Among Colorectal Cancer Patients: A Network Meta-Analysis of Randomized Controlled Trials', 'source': 'Frontiers', 'date': 'Jun 27, 2023', 'snippet': 'This study aimed to provide the complete efficacy and safety profiles and \nranking of systemic therapies for the treatment of unresectable advanced \nor...', 'thumbnail': 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'https://www.empr.com/home/news/drugs-in-the-pipeline/atopic-dermatitis-improvement-observed-with-ruxolitinib-cream-in-pediatric-trial/', 'title': 'Atopic Dermatitis Improvement Observed With Ruxolitinib Cream in Pediatric Trial', 'source': 'Medical Professionals Reference', 'date': 'Jul 12, 2023', 'snippet': 'Positive topline results were announced from a phase 3 trial evaluating the \nefficacy and safety of ruxolitinib cream in pediatric patients with \natopic...', 'thumbnail': 'https://serpapi.com/searches/672401a96531cb6eb855f93b/images/4dd75f0900b4ecca7a01c363b821b35ca92958450c4200e55a776af70bf2f1e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6511391997337341}",,,,,,,,,,['neutral'],neutral,1 NCT02456740,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1705848', 'title': 'A Controlled Trial of Erenumab for Episodic Migraine', 'source': 'The New England Journal of Medicine', 'date': 'Jan 5, 2018', 'snippet': 'We tested erenumab, a fully human monoclonal antibody that inhibits the \ncalcitonin gene–related peptide receptor, for the prevention of episodic \nmigraine.', 'thumbnail': 'https://serpapi.com/searches/672401aab5ecbb920dded6ed/images/e978cbe18b3c240ce488e83e857d6d1a9cbe9f7163537c7af10f60be2ef84599.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8950312733650208}",,,,,,,,,,['neutral'],neutral,1 NCT01669252,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-021-00282-0', 'title': 'The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers', 'source': 'Nature', 'date': 'Jun 7, 2021', 'snippet': 'The biology of breast cancer response to neoadjuvant therapy is \nunderrepresented in the literature and provides a window-of-opportunity \nto...', 'thumbnail': 'https://serpapi.com/searches/672401adf93388521a29a789/images/7b7a34cdd4d7fd4205fb565bbb4058226ec434e1e288d597e15ca29528fd2adc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Jamie Rossjohn, PhD, Monash Biomedicine Discovery Institute, \nAustralia...', 'thumbnail': 'https://serpapi.com/searches/672401ca7ec4ae3813c71f54/images/ce0c9e167a214d9fe3884808d9f063b345d25eaf3d44e85ac37177253077ea25.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9315586090087891}",,,,,,,,,,['neutral'],neutral,1 NCT03960580,"{'position': 1, 'link': 'https://www.pennmedicine.org/news/news-releases/2024/january/exhalation-system-improves-symptoms-of-chronic-sinus-infections', 'title': ""'Exhalation' System Improves Symptoms of Chronic Sinus Infections"", 'source': 'Penn Medicine', 'date': 'Jan 18, 2024', 'snippet': ""An exhalation delivery system that uses a patient's own breath to carry the \nanti-inflammatory compound fluticasone (EDS-FLU) directly to the sinuses \nreduced..."", 'thumbnail': 'https://serpapi.com/searches/672401e80664c984116fd9df/images/6d2e88b11747b7d67ad4a8c9475b52f5739e30bb298379179d8f858b5528b6be.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8489072918891907}",,,,,,,,,,['neutral'],neutral,1 NCT05616221,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/ap-pa02-safely-treat-pseudomonas-aeruginosa-infection/', 'title': 'Phage cocktail, AP-PA02, may safely treat Pseudomonas aeruginosa...', 'source': 'Cystic Fibrosis News Today', 'date': 'Mar 7, 2023', 'snippet': 'The phage therapy was well tolerated and eased Pseudomonas aeruginosa \nairway load in treated trial patients, Phase 2b CF study proposed.', 'thumbnail': 'https://serpapi.com/searches/672401f18e13c94185f183b7/images/504f77fbd38e83144fe86d88e3ee55c2f4d55652d3b318a3f09aaebddfdb12d3.png', 'sentiment': 'positive', 'sentiment_prob': 0.8077670931816101}",,,,,,,,,,['positive'],positive,1 NCT02311673,"{'position': 1, 'link': 'https://praderwillinews.com/news/prader-willi-syndrome-investigational-therapy-rm-853-acquired-rhythm-pharmaceuticals/', 'title': 'Rhythm Pharmaceuticals Acquires Rights to Develop Investigational Therapy RM-853', 'source': 'Prader-Willi Syndrome News', 'date': 'Apr 9, 2018', 'snippet': 'Rhythm Pharmaceuticals has acquired the rights to develop and commercialize \nRM-853, an investigational therapy currently in preclinical research for \nPrader-...', 'thumbnail': 'https://serpapi.com/searches/6724020f2da15795533ddac8/images/5255d25d08cf3fe696bee9dde62afdb85be2657a5a18707523092ea8b318e605.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.906080961227417}",,,,,,,,,,['neutral'],neutral,1 NCT04785144,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-clinical-trial-evaluating-moderna-covid-19-variant-vaccine-begins', 'title': 'NIH clinical trial evaluating Moderna COVID-19 variant vaccine begins', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Mar 31, 2021', 'snippet': 'This trial is enrolling adult volunteers in the Atlanta, Cincinnati, \nNashville and Seattle areas. At this time, the research sites...', 'thumbnail': 'https://serpapi.com/searches/67240216e45f33d6d2690976/images/6609609ef79ebbca82e5f2e717a67a49ef2af5b727aa108025aadb15da54e7e8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9455243349075317}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-022-29219-2', 'title': 'Protein-based SARS-CoV-2 spike vaccine booster increases cross-neutralization against SARS-CoV-2 variants of concern in non-human primates', 'source': 'Nature', 'date': 'Mar 31, 2022', 'snippet': 'The emergence of severe acute respiratory syndrome coronavirus 2 \n(SARS-CoV-2) variants that partly evade neutralizing antibodies raises...', 'thumbnail': 'https://serpapi.com/searches/67240216e45f33d6d2690976/images/6609609ef79ebbca74a5faf8754f2e49b4b3e83004073dc6e43f9540a494d958.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5325437784194946}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT05295875,"{'position': 1, 'link': 'https://www.pharmaceutical-technology.com/news/ada-2024-altimmunes-glp-1-drug-shows-weight-loss-potential/', 'title': 'ADA 2024: Altimmune’s GLP-1 drug shows weight loss potential', 'source': 'Pharmaceutical Technology', 'date': 'Jun 24, 2024', 'snippet': 'As the obesity drug development space gains traction, Altimmune shared \npositive data from a Phase II trial for pemvidutide.', 'thumbnail': 'https://serpapi.com/searches/672402186de1e482835ae27b/images/49ade9080485b795e0443facb433a09f78b698386a415c38551948a697fe6e2e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7039597034454346}",,,,,,,,,,['positive'],positive,1 NCT01304927,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-22734-8', 'title': 'RANKL regulates male reproductive function', 'source': 'Nature', 'date': 'Apr 23, 2021', 'snippet': 'This translational study suggests that RANKL is a regulator of male \nreproductive function, however, predictive biomarkers for treatment-outcome \nrequires...', 'thumbnail': 'https://serpapi.com/searches/67240230ec54100b3215bcbd/images/2580b0c07a9101d55f267c990ebaa6bf05417cee7b9e9dbadf733123850260f6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9219090342521667}",,,,,,,,,,['neutral'],neutral,1 NCT03670953,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/amneals-extended-release-carbidopa-levodopa-to-get-review/', 'title': 'Amneal’s Extended-release Carbidopa/Levodopa to Get Review |...', 'source': ""Parkinson's News Today"", 'date': 'Nov 14, 2022', 'snippet': ""The U.S. Food and Drug Administration (FDA) will review Amneal \nPharmaceuticals' application for IPX203, its extended-release..."", 'thumbnail': 'https://serpapi.com/searches/672403cef60b6f8ef9bda30e/images/3dd07681f4efffba33346ed0c38104c18278c17033101f1dae29c0d90c6bd04e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9473481774330139}","{'position': 2, 'link': 'https://www.neurologylive.com/view/rise-parkinson-disease-study-ipx-203-alberto-espay', 'title': 'The RISE-PD Study of IPX-203: Alberto J. Espay, MD, MSc', 'source': 'Neurology live', 'date': 'Oct 12, 2021', 'snippet': ""The research chair for Parkinson's Disease and Movement Disorders at \nUniversity of Cincinnati Health discussed the therapy's results in a..."", 'thumbnail': 'https://serpapi.com/searches/672403cef60b6f8ef9bda30e/images/3dd07681f4efffba4f3d95316c1d53fdba1fe486944775c241f7b7401e320563.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.953052818775177}","{'position': 3, 'link': 'https://parkinsonsnewstoday.com/news/application-parkinsons-therapy-ipx203-resubmitted-fda/', 'title': ""Application for Parkinson's therapy IPX203 resubmitted to FDA"", 'source': ""Parkinson's News Today"", 'date': 'Feb 12, 2024', 'snippet': ""Amneal Pharmaceuticals' IPX203 formulation for Parkinson's disease is \ndesigned to maintain steady bodily levels of carbidopa and levodopa."", 'thumbnail': 'https://serpapi.com/searches/672403cef60b6f8ef9bda30e/images/3dd07681f4efffba8eb634723faba8382d6d1346dfd934258f6fe152ab85540d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9042649269104004}","{'position': 4, 'link': 'https://parkinsonsnewstoday.com/news/aan-2022-ipx-203-extended-release-gives-more-good-on-time-dose-parkinsons-trial/', 'title': ""#AAN2022 - IPX-203 Reduced Parkinsons' 'Off Time' 1.5+ Hours in Trial"", 'source': ""Parkinson's News Today"", 'date': 'Mar 28, 2022', 'snippet': 'IPX-203, an extended-release version of CD/LD therapy, performed better \nthan immediate-release medicine, according to clinical trial data.', 'thumbnail': 'https://serpapi.com/searches/672403cef60b6f8ef9bda30e/images/3dd07681f4efffba1f44ae8186697514c5ba2fbfe23d513de74bc7832f0e752a.png', 'sentiment': 'positive', 'sentiment_prob': 0.5773031115531921}",,,,,,,"['neutral', 'neutral', 'neutral', 'positive']",neutral,1 NCT03035591,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-01077-z', 'title': 'First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours', 'source': 'Nature', 'date': 'Sep 29, 2020', 'snippet': 'Bromodomain and extra-terminal domain (BET) proteins are reported to be \nepigenetic anti-cancer drug targets. This first-in-human study...', 'thumbnail': 'https://serpapi.com/searches/6724024516779322118570c2/images/c8f2458204dd087d0b58d2737707c7a30d5f810fbb26e723826dba803d106007.png', 'sentiment': 'neutral', 'sentiment_prob': 0.90174800157547}",,,,,,,,,,['neutral'],neutral,1 NCT02294058,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/06/30/long-term-data-zeposia-help-cognitive-function-patients/', 'title': 'Long-term Zeposia May Help Cognitive Function in Patients, Data Show', 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 30, 2022', 'snippet': 'Long-term treatment with Zeposia stabilizes or even improves cognitive \nfunction in most adults with relapsing forms of MS, data show.', 'thumbnail': 'https://serpapi.com/searches/6724024d48b9f7f46b77579d/images/15d2aa0de0664ce9d2d1ba338d7894a609816199ac07bdba4e657f96beef27c2.png', 'sentiment': 'positive', 'sentiment_prob': 0.6353581547737122}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/02/14/zeposia-not-affect-heart-heath-long-term-use-trials/', 'title': 'Zeposia’s long-term use doesn’t affect heart health, Phase 3 trials show', 'source': 'Multiple Sclerosis News Today', 'date': 'Feb 14, 2023', 'snippet': 'Relapsing MS patients treated with oral Zeposia for up to 2 years in Phase \n3 trials show no clinically significant changes in heart health.', 'thumbnail': 'https://serpapi.com/searches/6724024d48b9f7f46b77579d/images/15d2aa0de0664ce942181746d03fe4f6f04d4b1a8ce88a55588391c911a6d990.png', 'sentiment': 'neutral', 'sentiment_prob': 0.705949604511261}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00289211,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0805538', 'title': 'Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema', 'source': 'The New England Journal of Medicine', 'date': 'Aug 5, 2010', 'snippet': 'We report the results of two randomized trials of nanofiltered C1 inhibitor \nconcentrate for the management of hereditary angioedema.', 'thumbnail': 'https://serpapi.com/searches/67240254316650e9680477db/images/a8fcf14e32675d743a7e647671110d0f317d6f8a6911a320ccfe979cbe0ea585.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9361838698387146}","{'position': 2, 'link': 'https://angioedemanews.com/cinryze/', 'title': 'Cinryze (human C1 esterase inhibitor) for hereditary angioedema', 'source': 'Angioedema News', 'date': 'Jan 9, 2024', 'snippet': 'Cinryze, marketed by Shire, is an approved injectable medicine to prevent \nsevere swelling attacks in people with hereditary angioedema...', 'thumbnail': 'https://serpapi.com/searches/67240254316650e9680477db/images/a8fcf14e32675d74db1ab0affb3d534a4c90dc0eaa116bf41ff2eebe279b6a21.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8004082441329956}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02191826,"{'position': 1, 'link': 'https://fapnewstoday.com/news/new-molecule-potentially-potent-fap-treatment/', 'title': 'New molecule seen as potentially potent FAP treatment', 'source': 'FAP News Today', 'date': 'Oct 30, 2023', 'snippet': 'Scientists in Spain developed PITB, a second-generation TTR stabilizer that \nwas more potent and effective than tolcapone in lab studies.', 'thumbnail': 'https://serpapi.com/searches/67240260be8013c71954fb24/images/3d7160dccd5aede226f37cab3a6744ca385069b7a743d5bf67f086a56049c1a5.png', 'sentiment': 'positive', 'sentiment_prob': 0.7142612338066101}","{'position': 2, 'link': 'https://www.nature.com/articles/ncomms10787', 'title': 'Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity', 'source': 'Nature', 'date': 'Feb 23, 2016', 'snippet': 'Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal \nsystemic amyloidoses. TTR tetramer dissociation precedes...', 'thumbnail': 'https://serpapi.com/searches/67240260be8013c71954fb24/images/3d7160dccd5aede2ad1fbc5a99dff98f85d64d414aa46aeb75b7bb6ab7b60312.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6535580158233643}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02752113,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-35589-4', 'title': 'Determinants of arterial stiffness in patients with type 2 diabetes mellitus: a cross sectional analysis', 'source': 'Nature', 'date': 'Jun 2, 2023', 'snippet': 'This is a cross-sectional analysis of arterial stiffness in 266 patients in \nthe early stage of T2DM who did not have cardiovascular or renal \ncomplications.', 'thumbnail': 'https://serpapi.com/searches/6724027ec7d4a1e0188e88c2/images/eeb6ad58be55f091eefc38eabec0374ba8ac3c979cda4e5bbea5143fbcb3d06d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9014810919761658}",,,,,,,,,,['neutral'],neutral,1 NCT00402831,"{'position': 1, 'link': 'https://www.empr.com/home/news/m-m-r-ii-varivax-proquad-vaccines-approved-for-intramuscular-administration/', 'title': 'M-M-R II, Varivax, ProQuad Vaccines Approved for Intramuscular Administration', 'source': 'Medical Professionals Reference', 'date': 'Mar 6, 2023', 'snippet': ""The Food and Drug Administration (FDA) has expanded the approval for \nMerck's MMR II (measles, mumps, and rubella virus vaccine live), Varivax \n(varicella virus..."", 'thumbnail': 'https://serpapi.com/searches/672402df2c83d5b81af4c11f/images/b813f186228b9d7517f4828ff586363b1751f440fd3fead8f82e9ba9a0fed19d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8451946973800659}",,,,,,,,,,['neutral'],neutral,1 NCT03010527,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/bimekizumab-UCB4940', 'title': 'Bimekizumab (Bimzelx®)', 'source': 'UCB', 'date': 'Oct 16, 2018', 'snippet': 'Ankylosing Spondylitis, A Multicenter Study to Evaluate the Efficacy and \nSafety of Different Doses of Bimekizumab in Subjects With Active \nAnkylosing...', 'thumbnail': 'https://serpapi.com/searches/6724029376079d039968ff9d/images/44098e76aa3c26570c8f047801882c70e92a92b34bdcc1e9bc12bf89a3ea8f0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8456552028656006}",,,,,,,,,,['neutral'],neutral,1 NCT02138916,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1905248', 'title': 'Benralizumab for the Prevention of COPD Exacerbations', 'source': 'The New England Journal of Medicine', 'date': 'May 20, 2019', 'snippet': 'In the GALATHEA and TERRANOVA trials, we enrolled patients with COPD (at a \nratio of approximately 2:1 on the basis of eosinophil count [≥220 per \ncubic...', 'thumbnail': 'https://serpapi.com/searches/67240298316650e93040c5be/images/6707c2d5928c1d4358d2ff6ff653d909b01bd8ff69a759a2936f949615b5d767.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8859856724739075}","{'position': 2, 'link': 'https://lungdiseasenews.com/2018/01/16/severe-eosinophilic-asthma-therapy-fasenra-benralizumab-astrazeneca-receives-eu-approval/', 'title': 'Fasenra Approved in EU for Treatment of Severe Eosinophilic Asthma', 'source': 'Lung Disease News', 'date': 'Jan 16, 2018', 'snippet': 'Read about the approval of Fasenra (benralizumab) in the EU for the \ntreatment of severe eosinophilic asthma. The U.S. FDA approved Fasenra...', 'thumbnail': 'https://serpapi.com/searches/67240298316650e93040c5be/images/6707c2d5928c1d439ad26619ec24fb54d0d20a60e23c2a9b58c81cab202f4c25.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.831265389919281}","{'position': 3, 'link': 'https://copdnewstoday.com/news/no-reduction-copd-exacerbations-add-on-fasenra-phase-3-trials/', 'title': 'No Reduction in COPD Exacerbations with Fasenra Add-on in Phase 3 Trials', 'source': 'COPD News Today', 'date': 'Jun 11, 2019', 'snippet': 'Add-on treatment with Fasenra (benralizumab) failed to reduce annual \nexacerbations in patients with moderate to very severe COPD,...', 'thumbnail': 'https://serpapi.com/searches/67240298316650e93040c5be/images/6707c2d5928c1d438a10895f35277e2210b7733d7b373a5022067ec8794c4984.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7574577331542969}",,,,,,,,"['neutral', 'neutral', 'negative']",neutral,1 NCT02969382,"{'position': 1, 'link': 'https://www.nature.com/articles/s41537-021-00190-z', 'title': 'Safety and effectiveness of ulotaront (SEP-363856) in schizophrenia: results of a 6-month, open-label extension study', 'source': 'Nature', 'date': 'Dec 9, 2021', 'snippet': 'Ulotaront, a trace amine-associated receptor 1 (TAAR1) and serotonin 5-HT1A \nreceptors agonist, has demonstrated efficacy in the treatment of...', 'thumbnail': 'https://serpapi.com/searches/672402a1bb55ff6f6c744400/images/a8d78613aaabab4f6164f90cab29d097c2ede73760055f4b3ca2fe351847d1c3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7764618396759033}",,,,,,,,,,['neutral'],neutral,1 NCT03597295,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2021/01/25/retifanlimab-under-fda-priority-review-for-advanced-anal-canal-cancer/', 'title': 'Retifanlimab Under FDA Priority Review for Advanced Anal Canal Cancer', 'source': 'Immuno-Oncology News', 'date': 'Jan 25, 2021', 'snippet': 'Retifanlimab is under FDA review for treating adults with advanced squamous \ncell carcinoma of the anal canal, who progressed after initial...', 'thumbnail': 'https://serpapi.com/searches/672402b62b5fa77e1b885b41/images/2d117e81697dfc00a8e80da10c457fca5e2e73a5379492a95639eebfc0c2e017.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8957542777061462}",,,,,,,,,,['neutral'],neutral,1 NCT02965001,"{'position': 1, 'link': 'https://jnm.snmjournals.org/content/63/8/1169', 'title': 'Prognostic Value of Urokinase-Type Plasminogen Activator Receptor PET/CT in Head and Neck Squamous Cell Carcinomas and Comparison with 18F-FDG PET/CT: A Single-Center Prospective Study', 'source': 'Journal of Nuclear Medicine', 'date': 'Aug 1, 2022', 'snippet': 'Abstract. The aim of this phase II clinical trial (NCT02965001) was to \nevaluate the prognostic value of urokinase-type plasminogen activator...', 'thumbnail': 'https://serpapi.com/searches/672402bfd403e1663f070f6a/images/fbea3c88dbf06e753926d4bc048c2ed9e9b52d8c38d8d061c77e5c102136e5a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8865150809288025}",,,,,,,,,,['neutral'],neutral,1 NCT00441207,"{'position': 1, 'link': 'https://www.researchgate.net/publication/355780963_High-dose_intravenous_vitamin_C_a_promising_multi-targeting_agent_in_the_treatment_of_cancer', 'title': '(PDF) High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer', 'source': 'ResearchGate', 'date': 'Nov 4, 2021', 'snippet': 'Mounting evidence indicates that vitamin C has the potential to be a potent \nanti-cancer agent when administered intravenously and in high doses \n(high-dose IVC).', 'thumbnail': 'https://serpapi.com/searches/672402c56de1e482835ae296/images/7f92810abdb5eb139656c28e84830c0aa9b54d46f5ae0db04a45ef1cce170920.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7034693956375122}",,,,,,,,,,['positive'],positive,1 NCT01764841,"{'position': 1, 'link': 'https://bronchiectasisnewstoday.com/2017/07/18/ciprofloxacin-dpi-bayer-treating-non-cystic-fibrosis-bronchiectasis/', 'title': 'Bayer’s Ciprofloxacin DPI Shows Promise in Treating Non-cystic Fibrosis Bronchiectasis', 'source': 'Bronchiectasis News Today', 'date': 'Jul 18, 2017', 'snippet': 'Bayer is conducting two Phase 3 clinical trials evaluating ciprofloxacin \nDry Powder for Inhalation (ciprofloxacin DPI) as a treatment for...', 'thumbnail': 'https://serpapi.com/searches/672402c78a7c0972a22e3525/images/b91c10e1bd445f0cc2023b8abd5863bd17607f075db39c16b5d816ac721a0090.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7611814737319946}","{'position': 2, 'link': 'https://bronchiectasisnewstoday.com/2017/11/17/fda-panel-opposed-ciprofloxacin-dry-powder-for-inhalation-cipro-dpi-to-treat-non-cf-bronchiectasis/', 'title': 'FDA Panel Opposes Use of Cipro DPI to Treat Non-CF Bronchiectasis', 'source': 'Bronchiectasis News Today', 'date': 'Nov 17, 2017', 'snippet': 'A US Food and Drug Administration (FDA) advisory panel voted not to \nrecommend ciprofloxacin dry powder for inhalation (Cipro DPI), being \ndeveloped by Bayer, to...', 'thumbnail': 'https://serpapi.com/searches/672402c78a7c0972a22e3525/images/b91c10e1bd445f0c1835a7e9c01816840176d738d0680e03428778e8f7f49cd8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5384337902069092}","{'position': 3, 'link': 'https://bronchiectasisnewstoday.com/2018/01/04/top-10-bronchiectasis-stories-2017/', 'title': 'Top 10 Bronchiectasis Stories of 2017', 'source': 'Bronchiectasis News Today', 'date': 'Jan 4, 2018', 'snippet': ""Here are Bronchiectasis News Today's Top 10 most-read stories of 2017 with \nsummaries of why they were interesting to bronchiectasis patients..."", 'thumbnail': 'https://serpapi.com/searches/672402c78a7c0972a22e3525/images/b91c10e1bd445f0c852361e8b986483bf4eb78911ba197dd4d7fb618f2c5a068.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5398268699645996}",,,,,,,,"['neutral', 'neutral', 'positive']",neutral,1 NCT04874350,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/lpcn-1148-phase-2-study-meets-primary-endpoint-in-patients-with-cirrhosis-301886930.html', 'title': 'LPCN 1148 Phase 2 Study Meets Primary Endpoint in Patients with Cirrhosis', 'source': 'PR Newswire', 'date': 'Jul 27, 2023', 'snippet': 'This Phase 2 proof of concept study is an ongoing randomized \nplacebo-controlled study in sarcopenic male patients with cirrhosis on the \nliver transplant...', 'thumbnail': 'https://serpapi.com/searches/6724032f4a4a1df3ffaf03e2/images/aff36becaef0228807fb0165398d66314c7dd70ea2a22bd854ac05553f649dea.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9118776917457581}",,,,,,,,,,['neutral'],neutral,1 NCT02128958,"{'position': 1, 'link': 'https://www.onclive.com/view/state-of-science-summit-gastrointestinal-cancer---chaired-by-tanios-bekaii-saab-md-and-darshil-shah-md-mph', 'title': 'State of Science Summit: Gastrointestinal Cancer - Chaired by: Tanios Bekaii-Saab, MD and Darshil Shah, MD, MPH', 'source': 'OncLive', 'date': '1 month ago', 'snippet': 'State of Science Summit: Gastrointestinal Cancer - Chaired by: Tanios \nBekaii-Saab, MD and Darshil Shah, MD, MPH.', 'thumbnail': 'https://serpapi.com/searches/67240348b2ebaee6e82f3ba2/images/8df87159b5d6879539fcc9fc823652a318c40716dc06f4390d10d1e346bfc182.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8446627259254456}","{'position': 2, 'link': 'https://www.onclive.com/view/dr-sapisochin-on-neoadjuvant-treatment-for-hcc', 'title': 'Dr. Sapisochin on Neoadjuvant Treatment for HCC', 'source': 'OncLive', 'date': 'Sep 20, 2018', 'snippet': 'Gonzalo Sapisochin, MD, assistant professor of surgery, University of \nToronto, discusses neoadjuvant treatment for patients with hepatocellular \ncarcinoma (HCC).', 'thumbnail': 'https://serpapi.com/searches/67240348b2ebaee6e82f3ba2/images/8df87159b5d68795ba431e2524ba186951f6a53e3840383946200ac436747427.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9181070327758789}","{'position': 3, 'link': 'https://www.onclive.com/view/dr-hidalgo-medina-on-treatment-considerations-in-pancreatic-cancer', 'title': 'Dr. Hidalgo Medina on Treatment Considerations in Pancreatic Cancer', 'source': 'OncLive', 'date': 'Dec 4, 2019', 'snippet': 'Manuel Hidalgo Medina, MD, PhD, chief, Division of Hematology and Medical \nOncology, Weill Cornell Medicine/NewYork-Presbyterian Hospital,...', 'thumbnail': 'https://serpapi.com/searches/67240348b2ebaee6e82f3ba2/images/8df87159b5d68795f48dd6bb1186b0c5bba37adef6ca46c5155cab9ed9cee8c2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.934554398059845}","{'position': 4, 'link': 'https://www.onclive.com/view/dr-oneil-on-neuroendocrine-tumors', 'title': ""Dr. O'Neil on Neuroendocrine Tumors"", 'source': 'OncLive', 'date': 'May 21, 2018', 'snippet': ""Bert O'Neil, MD, the Joseph W. and Jackie J. Cusick Professor of Oncology, \nprofessor of medicine, and director of the Phase I and..."", 'thumbnail': 'https://serpapi.com/searches/67240348b2ebaee6e82f3ba2/images/8df87159b5d687956682399807616ebae8441115871a9eba7111b712ade142a1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9435071349143982}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04685265,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.852003/full', 'title': ""Alpha-Synuclein Targeting Therapeutics for Parkinson's Disease and Related Synucleinopathies"", 'source': 'Frontiers', 'date': 'Feb 13, 2024', 'snippet': 'Here, we review recent pre-clinical and clinical work that offers promising \ntreatment strategies to sequester, degrade, or silence asyn expression.', 'thumbnail': 'https://serpapi.com/searches/67240349f3cbfa2f8b13c134/images/d35ca066d46bbee5858c641b6959118708de976f392b1ad9e3572297e84fc480.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8726274967193604}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-022-32797-w', 'title': 'The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils', 'source': 'Nature', 'date': 'Sep 14, 2022', 'snippet': 'Aggregation of amyloidogenic proteins is a characteristic of multiple \nneurodegenerative diseases. Atomic resolution of small molecule...', 'thumbnail': 'https://serpapi.com/searches/67240349f3cbfa2f8b13c134/images/d35ca066d46bbee570fd00430ae8368ce84c17b5ce37ef7636ad43f3f86bd251.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8575400710105896}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03105128,"{'position': 1, 'link': 'https://ibdnewstoday.com/2021/01/18/risankizumab-induces-clinical-endoscopic-remission-after-12-weeks-in-crohns-disease-clinical-trials/', 'title': ""Crohn's Remission Shown After 12 Weeks in Risankizumab Clinical Trial"", 'source': 'ibdnewstoday.com', 'date': 'Jan 18, 2021', 'snippet': ""Treatment with risankizumab for 12 weeks induced both clinical and \nendoscopic remission in people with Crohn's disease, trial data show."", 'thumbnail': 'https://serpapi.com/searches/6724034b7d533e6839e29268/images/1260b470d06b690eba5ba639de63c36a8315197b600bc99ddab164dfac6da297.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.879081130027771}",,,,,,,,,,['neutral'],neutral,1 NCT02040298,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00027-9/fulltext?rss=yes', 'title': 'Clinical trials for progressive multiple sclerosis: progress, new lessons learned, and remaining challenges', 'source': 'The Lancet', 'date': 'Feb 15, 2024', 'snippet': 'Several immunomodulatory approaches that have modest but clinically \nmeaningful effects have been approved for the management of progressive \nmultiple sclerosis.', 'thumbnail': 'https://serpapi.com/searches/672403559fd3095e762f8e10/images/c29c1e3afc75c5cb1e4b52bb341bb75cb2a0de101468a51be2dc99a97a082d95.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8122972249984741}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/tavist-clemastinetavist-clemastine/', 'title': 'Tavist (Clemastine) for RRMS', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 13, 2017', 'snippet': 'Tavist (clemastine) is an over-the-counter antihistamine that is being \ndeveloped as a potential treatment for relapsing remitting multiple \nsclerosis (RRMS).', 'thumbnail': 'https://serpapi.com/searches/672403559fd3095e762f8e10/images/c29c1e3afc75c5cb6b0765f8c7ba3b0fec7279f8ac31d75ae4f5952f04966fd5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8968601822853088}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04089579,"{'position': 1, 'link': 'https://www.vice.com/en/article/duke-stem-cells-autism-cryocell/', 'title': 'Duke Has Quietly Discontinued a Costly, Unproven Autism Treatment', 'source': 'VICE', 'date': 'Apr 17, 2023', 'snippet': 'For several years, parents of autistic children have paid between $10,000 \nand $15,000 to have their children undergo unproven stem cell and...', 'thumbnail': 'https://serpapi.com/searches/6724036274f0a4921704ed49/images/532ef8ac461d5908c2b870e62c69ee83e0ba7cfc3d0fd9f2982f03530d440d68.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5620641708374023}",,,,,,,,,,['neutral'],neutral,1 NCT03831295,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-023-00364-1', 'title': 'Applications and clinical trial landscape using Toll-like receptor agonists to reduce the toll of cancer', 'source': 'Nature', 'date': 'Mar 8, 2023', 'snippet': 'In this review, we describe the TLR agonists that are being evaluated \nclinically as new therapies for solid tumors.', 'thumbnail': 'https://serpapi.com/searches/6724036b9872179945fc35ac/images/205a9ac660bd7e76ffa07be419454e7b162d9cfd73e07cc2b1cf3a027d914222.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9042466282844543}",,,,,,,,,,['neutral'],neutral,1 NCT03422510,"{'position': 1, 'link': 'https://www.nature.com/articles/s41581-021-00427-1', 'title': 'Therapeutic trials in adult FSGS: lessons learned and the road forward', 'source': 'Nature', 'date': 'May 20, 2021', 'snippet': 'Focal segmental glomerulosclerosis (FSGS) is not a specific disease entity \nbut a lesion that primarily targets the podocyte.', 'thumbnail': 'https://serpapi.com/searches/6724037f1fc7c51f052f05c5/images/5a40d8a56331359ed162f6b4d449996e306f60f1bb67cf76e575b43f0aa7fe99.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8861932754516602}",,,,,,,,,,['neutral'],neutral,1 NCT04369586,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01323-9', 'title': 'Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial', 'source': 'Nature', 'date': 'Jan 30, 2023', 'snippet': 'Meplazumab, a humanized CD147 antibody, has shown favourable safety and \nefficacy in our previous clinical studies. In DEFLECT (NCT04586153)...', 'thumbnail': 'https://serpapi.com/searches/672403a5708e2e993b0dd95e/images/97d45dfba701ff28b0eae2c442bf0c6351fd556c753b99796fd8d6562931b47a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5692375302314758}",,,,,,,,,,['neutral'],neutral,1 NCT02606682,"{'position': 1, 'link': 'https://www.apdaparkinson.org/article/future-parkinsons-disease-treatments/', 'title': 'The Future of Parkinson’s Disease Treatments', 'source': 'American Parkinson Disease Association', 'date': 'Aug 25, 2020', 'snippet': 'There are many new and exciting potential therapies that are under \ninvestigation and we will continue to update you as results of these trials \nare available.', 'thumbnail': 'https://serpapi.com/searches/672403b4f9f904be4fe0a50a/images/763fdf5e92e755a3ce90d18ef6c37c675703119d777e6f1d4b4e114f2775d3ac.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7533977031707764}",,,,,,,,,,['positive'],positive,1 NCT04561258,"{'position': 1, 'link': 'https://www.europeanpharmaceuticalreview.com/news/155658/first-patient-treated-with-potentially-curative-hiv-cell-and-gene-therapy/', 'title': 'First patient treated with potentially curative HIV cell and gene therapy', 'source': 'European Pharmaceutical Review', 'date': 'Jun 1, 2021', 'snippet': 'The first-in-human study will evaluate the safety and efficacy AGT103-T, a \ncell and gene therapy product for HIV, in up to six participants.', 'thumbnail': 'https://serpapi.com/searches/672403c2d364b4f6fa6df322/images/4d874fa47c16accf1c4c670cca27e9f3b1dda3ece05d882350ca1224f03d22f7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8429476022720337}","{'position': 2, 'link': 'https://www.cgtlive.com/view/conant-more-research-needed-hiv-therapies', 'title': 'Marcus Conant, MD, on More Research Needed With HIV Therapies', 'source': 'CGTLive®', 'date': 'Jun 4, 2024', 'snippet': 'The Chief Medical Officer of Addimmune discussed the unmet need with HIV \nand research the company is conducting.', 'thumbnail': 'https://serpapi.com/searches/672403c2d364b4f6fa6df322/images/4d874fa47c16accf1410a4018a02000786358e809b21e663187f6c451c190d19.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9322260618209839}","{'position': 3, 'link': 'https://www.prnewswire.com/news-releases/agt-announces-progress-with-hiv-cure-program-phase-1-clinical-trial-301300466.html', 'title': 'AGT Announces Progress with HIV Cure Program, Phase 1 Clinical Trial', 'source': 'PR Newswire', 'date': 'May 27, 2021', 'snippet': 'PRNewswire/ -- American Gene Technologies (AGT), a clinical-stage \nbiotechnology company, announced treatment of the first participant in \nits...', 'thumbnail': 'https://serpapi.com/searches/672403c2d364b4f6fa6df322/images/4d874fa47c16accfc3114bcfc29f299bb2c022afe893a83aee70fa5215e74bd0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7963420748710632}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01592370,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/hematology/articles/10.3389/frhem.2023.1244494/full', 'title': 'Nivolumab and daratumumab combination regimens for the treatment of relapsed and refractory multiple myeloma: results of a randomized phase I/II clinical trial', 'source': 'Frontiers', 'date': 'Sep 12, 2023', 'snippet': 'PurposeThe phase I/II trial CheckMate 039 (NCT01592370) evaluated the \nsafety, tolerability, and efficacy of nivolumab-daratumumab (ND) in...', 'thumbnail': 'https://serpapi.com/searches/672403c158e433cfdc86995c/images/2ea290601f982697039cd6ff5162882c1df9c5691961b3217eedf82c5abb21f8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9009431004524231}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/safety-concerns-prompt-fda-to-put-a-hold-on-opdivo-combination-trials-for-myeloma/', 'title': '3 Myeloma Trials of Opdivo Put on Hold Due to Safety Concerns Over Other Therapies', 'source': 'Myeloma Research News', 'date': 'Sep 8, 2017', 'snippet': 'The US Food and Drug Administration has ordered Bristol-Myers Squibb to put \na hold on three clinical trials evaluating Opdivo (nivolumab) in \ncombination with...', 'thumbnail': 'https://serpapi.com/searches/672403c158e433cfdc86995c/images/2ea290601f982697af35f930eb56b23458154036ffc0b641531f42c7ce6c0a35.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7855069041252136}","{'position': 3, 'link': 'https://www.nature.com/articles/s41598-023-50262-6', 'title': 'Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab', 'source': 'Nature', 'date': 'Jan 7, 2024', 'snippet': 'Lirilumab, the most clinically advanced NK cell checkpoint inhibitor, \ntargets inhibitory killer immunoglobulin-like receptors (KIRs), however it \nhas yet to...', 'thumbnail': 'https://serpapi.com/searches/672403c158e433cfdc86995c/images/2ea290601f982697620876972e98c1bc4460926e6ad977638fad2323afe4dbe0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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increase the clinical applicability of PET-MPI \nby designing and synthesizing fluorinated ammonium salt derivatives.', 'thumbnail': 'https://serpapi.com/searches/67240487f922f6c63082ec99/images/8e0202b8ea802854d96029bb35901dc8ec3459bbe2ab4eadc78365ac58357768.png', 'sentiment': 'neutral', 'sentiment_prob': 0.871613621711731}",,,,,,,,,,['neutral'],neutral,1 NCT00809562,"{'position': 1, 'link': 'https://www.psychiatrictimes.com/view/ketamine-induced-optimism-new-hope-development-rapid-acting-antidepressants', 'title': 'Ketamine-Induced Optimism: New Hope for the Development of Rapid-Acting Antidepressants', 'source': 'Psychiatric Times', 'date': 'Jul 13, 2012', 'snippet': 'There is rapidly escalating interest in drugs that target the glutamatergic \nneurotransmitter system, especially NMDA receptor modulators.', 'thumbnail': 'https://serpapi.com/searches/67240495d997ab53a5e9a57d/images/5f49d7a12e3882f1791e8cb10847ad2ba9cfef1bf9f7fb36584ddb22412aecd0.jpeg', 'sentiment': 'positive', 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We also show that tofacitinib improves cardiometabolic and \nimmunologic parameters."", 'thumbnail': 'https://serpapi.com/searches/672404e0cb33d0457864580d/images/844e9cafacd69a994a4782de7b56156b5bf4c0f12438c7159494157b3d8b2710.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6576781868934631}",,,,,,,,,,['positive'],positive,1 NCT02323412,"{'position': 1, 'link': 'https://www.bmj.com/content/367/bmj.l5654', 'title': 'Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial', 'source': 'The BMJ', 'date': 'Oct 16, 2019', 'snippet': '... placebo controlled, multicentre trial. BMJ 2019; 367 doi: \nhttps://doi.org/10.1136/bmj.l5654 (Published 16 October 2019) Cite this as: \nBMJ 2019;367:l5654.', 'thumbnail': 'https://serpapi.com/searches/672404fc6cca5eff81971515/images/c0c78698d47bea707a8f9bad16129a65bc86209b6342eda46b3d5bedfd256870.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8757321238517761}",,,,,,,,,,['neutral'],neutral,1 NCT01740557,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1018962/full', 'title': 'Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': '1Department of Immunology, School of Medicine, Iran University of Medical \nSciences, Tehran, Iran; 2Immunology Research Center, Institute of \nImmunology and...', 'thumbnail': 'https://serpapi.com/searches/67240501123457bbbd4c2516/images/dd2b73ed15a16e99c56312af44ed67edf75a2194d146e9feb314824139b49e5b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7887113094329834}",,,,,,,,,,['neutral'],neutral,1 NCT01563263,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-023-00672-4', 'title': 'Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa | npj Vaccines', 'source': 'Nature', 'date': 'May 25, 2023', 'snippet': 'Pseudomonas aeruginosa (PA) is a leading cause of hospital-acquired and \nventilator-associated pneumonia. The multidrug-resistance (MDR) rate...', 'thumbnail': 'https://serpapi.com/searches/67240521059caf91502b3f5c/images/030e314329f4e15d32e78c370b006db5da486f6e34684e957b18e71f37ed99c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7648937106132507}",,,,,,,,,,['neutral'],neutral,1 NCT00117676,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0802878', 'title': 'Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B', 'source': 'The New England Journal of Medicine', 'date': 'Dec 4, 2008', 'snippet': 'Tenofovir disoproxil fumarate (DF) is a nucleotide analogue and a potent \ninhibitor of human immunodeficiency virus type 1 reverse...', 'thumbnail': 'https://serpapi.com/searches/67240523a5aae957db4375b1/images/43310ec6f3d15ef402057d0eb3ea2e4fd93e924ab1eec4aaec1662c3b737d399.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8598584532737732}",,,,,,,,,,['neutral'],neutral,1 NCT02354131,"{'position': 1, 'link': 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20, 2023', 'snippet': 'The phase 3 VAPAUS study evaluated QTORIN™ 3.9% rapamycin anhydrous gel for \nthe treatment of adults with pachyonychia congenita.', 'thumbnail': 'https://serpapi.com/searches/67240535400bd5fee9261208/images/a82546bab7b643404ad147ebcb8754f5387ad577f9b01f111282f381e84e1467.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8269616365432739}",,,,,,,,,,['neutral'],neutral,1 NCT02138162,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/jcpt.12503', 'title': 'A comparison of the pharmacokinetics and safety of enzalutamide in subjects with hepatic impairment and matched healthy subjects', 'source': 'Wiley Online Library', 'date': 'Mar 1, 2017', 'snippet': 'Enzalutamide, an androgen receptor inhibitor approved for the treatment of \nmetastatic castration-resistant prostate cancer, is eliminated...', 'thumbnail': 'https://serpapi.com/searches/672405427ebde514439a8312/images/9f87039a8ea2702154bb5e5f2f8d5e32957abf86cdd1c5afaa53e3354c45c42c.png', 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'Pharmacy Practice News', 'date': 'Nov 23, 2023', 'snippet': 'Phase 3 clinical trial results demonstrating that semaglutide 2.4 mg \nreduces the incidence of major cardiovascular events may enable the drug to \nbe...', 'thumbnail': 'https://serpapi.com/searches/67240559b4e8d6482d623285/images/215b3d4a34c84d4dc8bc0ce6062e15fce8188e1a3181e939095e819664e23803.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6485494375228882}","{'position': 2, 'link': 'https://www.clinicaltrialsarena.com/features/obesity-trial-surge-puts-the-focus-back-on-decentralisation/', 'title': 'Obesity trial surge puts the focus back on decentralisation', 'source': 'Clinical Trials Arena', 'date': '3 weeks ago', 'snippet': 'As obesity clinical trials evolve, there is a growing emphasis on how \ndecentralisation and new technologies can play a role.', 'thumbnail': 'https://serpapi.com/searches/67240559b4e8d6482d623285/images/215b3d4a34c84d4d1454c878cc78484353b4a80e925684d57721728ee94dca47.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6600452065467834}","{'position': 3, 'link': 'https://www.drugtopics.com/view/aha-semaglutide-significantly-reduces-mace-in-adults-with-overweight-or-obesity-cvd', 'title': 'AHA: Semaglutide Significantly Reduces MACE in Adults With Overweight or Obesity, CVD', 'source': 'Drug Topics', 'date': 'Nov 14, 2023', 'snippet': 'Data demonstrated a 20% risk reduction for major adverse cardiovascular \nevents in adults with overweight or obesity and established cardiovascular \ndisease.', 'thumbnail': 'https://serpapi.com/searches/67240559b4e8d6482d623285/images/215b3d4a34c84d4daecddca1291079882bca8550ffe896d55c16b35796f92038.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7996431589126587}","{'position': 4, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/semaglutide-2-4mg-cuts-mace-risk-in-obese-overweight-patients/', 'title': 'Semaglutide 2.4mg Cuts MACE Risk in Obese, Overweight Patients', 'source': 'Medical Professionals Reference', 'date': 'Aug 8, 2023', 'snippet': 'Semaglutide 2.4 mg reduces the risk of major adverse cardiovascular events \nby 20% in adults with overweight or obesity in the SELECT trial.', 'thumbnail': 'https://serpapi.com/searches/67240559b4e8d6482d623285/images/215b3d4a34c84d4d98fe5c1d886d2bf373249f72c10f237e3216deb791a64ed8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7005930542945862}",,,,,,,"['positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT02698735,"{'position': 1, 'link': 'https://epidermolysisbullosanews.com/news/antibiotic-gentamicin-may-show-promise-certain-epidermolysis-bullosa-patients/', 'title': 'Some Epidermolysis Bullosa Patients May Benefit from Use of Gentamicin', 'source': 'Epidermolysis Bullosa News', 'date': 'Aug 24, 2017', 'snippet': 'Short-term application of the antibiotic gentamicin, either topical or \nintradermal, reversed the effect of nonsense mutations in a small group of \npatients.', 'thumbnail': 'https://serpapi.com/searches/6724056e123457bbede2d22b/images/4492e6b8bf31efd5079ca1b500c5a44f1e670f2db2601d46b5ffc94193b0384c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.720325231552124}","{'position': 2, 'link': 'https://epidermolysisbullosanews.com/news/gentamicin-may-improve-outcome-80-percent-herlitz-jeb-patients/', 'title': 'In Herlitz JEB, Gentamicin May Improve Outcome in 80% of Patients', 'source': 'Epidermolysis Bullosa News', 'date': 'Jul 30, 2018', 'snippet': 'Read about a study showing that the antibiotic gentamicin may be beneficial \nfor about 80% of patients with Herlitz JEB who have LAMB3...', 'thumbnail': 'https://serpapi.com/searches/6724056e123457bbede2d22b/images/4492e6b8bf31efd5fd9551d65294b32a6503115f02917caaa9c1134bed343a6b.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8839682936668396}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02775435,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1810865', 'title': 'Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 25, 2018', 'snippet': 'Standard first-line therapy for metastatic, squamous non–small-cell lung \ncancer (NSCLC) is platinum-based chemotherapy or pembrolizumab (for...', 'thumbnail': 'https://serpapi.com/searches/6724057b7ebde51475550db8/images/4a5472c92830fe89e96be74e3819fa77129ec5b335956250de055a2971c6bd76.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8316283226013184}",,,,,,,,,,['neutral'],neutral,1 NCT00749450,"{'position': 1, 'link': 'https://coloncancernewstoday.com/2017/06/06/certain-colon-cancer-patients-may-require-shorter-chemotherapy-course/', 'title': 'Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds', 'source': 'Colon Cancer News Today', 'date': 'Jun 6, 2017', 'snippet': 'Chemotherapy following surgery could be reduced from six to three months in \ncertain colon cancer patients, according to an analysis of 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A Position Paper From the SAAWP of the EBMT', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': '1Department of Clinical Medicine and Surgery, Federico II University of \nNaples, Naples, Italy; 2Severe Aplastic Anemia Working Party of the \nEuropean Group...', 'thumbnail': 'https://serpapi.com/searches/67240841d0253e3d8bb512a8/images/fd89841dc056e52062085be14995ecdc69e3d640625a51d924a7675331c0bb2b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7861200571060181}",,,,,,,,,,['neutral'],neutral,1 NCT03069703,"{'position': 1, 'link': 'https://ancavasculitisnews.com/news/higher-dose-pneumonia-vaccine-boosts-immunity-aav-rituximab/', 'title': 'Higher Dose Pneumonia Vaccine Boosts Immunity for AAV Patients |...', 'source': 'ANCA Vasculitis News', 'date': 'Nov 14, 2022', 'snippet': 'AAV patients in trial given a pneumonia vaccination at higher dose showed \nstronger immune responses to bacteria than those on standard...', 'thumbnail': 'https://serpapi.com/searches/672405bad771bdf678dc54e6/images/03a1d6f91d712dc539afe59bd4c691dcaada84f9eb5123c2031d42fd68f1ed77.png', 'sentiment': 'positive', 'sentiment_prob': 0.5563899874687195}",,,,,,,,,,['positive'],positive,1 NCT05051579,"{'position': 1, 'link': 'https://investor.lilly.com/news-releases/news-release-details/lillys-phase-2-results-published-new-england-journal-medicine', 'title': ""Lilly's phase 2 results published in the New England Journal of Medicine show orforglipron, a once-daily oral nonpeptide GLP-1 receptor agonist, achieved up to 14.7% mean weight reduction at 36 weeks in adults with obesity or overweight"", 'source': 'Eli Lilly and Company', 'date': 'Jun 23, 2023', 'snippet': 'Orforglipron, a once-daily oral nonpeptide GLP-1 receptor agonist, achieved \nup to 14.7% mean weight reduction at 36 weeks in adults with obesity or \noverweight.', 'thumbnail': 'https://serpapi.com/searches/672405d0707fd367742aa251/images/748143c7fea99b48c1771120f55084cb1a57d4e463b42b1b5247c542b0128245.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8391620516777039}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2302392', 'title': 'Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity', 'source': 'The New England Journal of Medicine', 'date': 'Jun 23, 2023', 'snippet': 'Obesity is a major risk factor for many leading causes of illness and death \nworldwide. 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with EPP spend more time in the sun with bitopertin: Phase 2 trial', 'source': 'Porphyria News', 'date': 'Dec 13, 2023', 'snippet': 'Treatment with the oral therapy bitopertin substantially increased sunlight \ntolerance for adults with erythropoietic protoporphyria (EPP) in a Phase 2 \nclinical...', 'thumbnail': 'https://serpapi.com/searches/6724066d163bdf81353cfecc/images/d18aa7980af96a6988e9cb3f661d2fdb12a4eff07c33595a292ba993a643e95d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6675302386283875}","{'position': 2, 'link': 'https://www.sciencedirect.com/science/article/abs/pii/S1550413124000846?via%3Dihub', 'title': 'A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis', 'source': 'ScienceDirect.com', 'date': 'Apr 2, 2024', 'snippet': 'We found that bitopertin, a clinical-stage glycine uptake inhibitor, \nsuppresses osteoclast differentiation and ameliorates ovariectomy-induced \nbone loss by...', 'thumbnail': 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patients', 'source': 'Porphyria News', 'date': 'Jun 14, 2023', 'snippet': 'Bitopertin increased sunlight tolerance and life quality for erythropoietic \nprotoporphyria (EPP) patients in a clinical trial, results show.', 'thumbnail': 'https://serpapi.com/searches/6724066d163bdf81353cfecc/images/d18aa7980af96a69665597ec00e35914d729787c16561f0c2384475ae9336f39.png', 'sentiment': 'positive', 'sentiment_prob': 0.7560920119285583}","{'position': 5, 'link': 'https://porphyrianews.com/news/beacon-aurora-trials-of-bitopertin-complete-enrollment/', 'title': 'BEACON, AURORA trials of bitopertin complete enrollment', 'source': 'Porphyria News', 'date': 'Nov 15, 2023', 'snippet': 'The BEACON and AURORA Phase 2 clinical trials testing the investigational \noral therapy bitopertin in people with erythropoietic porphyrias...', 'thumbnail': 'https://serpapi.com/searches/6724066d163bdf81353cfecc/images/d18aa7980af96a69ce25351b584cb31ad901386d0761aa642fad247d5a27b0bf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8817107081413269}",,,,,,"['neutral', 'neutral', 'positive', 'positive', 'neutral']",neutral,1 NCT03918629,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0264410X23012963', 'title': 'A phase 3 study evaluating the lot consistency, immunogenicity, safety, and tolerability of a Clostridioides difficile vaccine in healthy adults 65 to 85 years of age', 'source': 'ScienceDirect.com', 'date': 'Dec 7, 2023', 'snippet': 'Three doses (Months 0,1,6) of toxoid-based C difficile vaccine induced \nrobust neutralizing antibody responses and were well tolerated in healthy \nparticipants...', 'thumbnail': 'https://serpapi.com/searches/6724066d069e5712506e0bae/images/dca7a3132e90146495ece7727330450c875f8c2cac7194990459232764f1bce2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7878576517105103}",,,,,,,,,,['neutral'],neutral,1 NCT02048865,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1814468', 'title': 'Apixaban to Prevent Venous Thromboembolism in Patients with Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Dec 4, 2018', 'snippet': 'Patients with active cancer have an increased risk of venous \nthromboembolism, which results in substantial morbidity, mortality,...', 'thumbnail': 'https://serpapi.com/searches/67240783069e5712506e0be1/images/8dbb50845d32e3fe36500ea84b67d141df4dcf3ee3c931c235ef4ce3ac31ad65.png', 'sentiment': 'negative', 'sentiment_prob': 0.6136891841888428}",,,,,,,,,,['negative'],negative,0 NCT03969888,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/addition-3-cftr-modulators-sionas-efforts-cf-franchise/', 'title': ""Addition of 3 CFTR modulators aids Sionna's efforts to expand CF 'franchise '"", 'source': 'Cystic Fibrosis News Today', 'date': 'Jul 17, 2024', 'snippet': 'Sionna has won the rights to three AbbVie clinical-stage compounds to \nexpand its pipeline of small molecules for restoring CFTR function.', 'thumbnail': 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'source': 'Frontiers', 'date': 'May 23, 2022', 'snippet': 'Chimeric antigen receptor T cell (CAR-T) therapy demonstrated remarkable \nsuccess in long-term remission of cancers and other autoimmune...', 'thumbnail': 'https://serpapi.com/searches/672407f6bcd65222bfec9063/images/ee2fd838907c92fa2ef8a8200d0621b60c4d783b44d2610fb40bd5bd3eab31b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6530438661575317}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2024/01/23/fda-grants-fast-track-status-kyv-101-progressive-forms-ms/', 'title': 'FDA grants fast track status to KYV-101 for progressive forms of MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Jan 23, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has granted fast track status to \nKYV-101, Kyverna Therapeutics' cell-based therapy candidate for people \nwith..."", 'thumbnail': 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'https://www.targetedonc.com/view/recent-long-term-data-on-parp-inhibitors-in-ovarian-cancer', 'title': 'Recent Long-Term Data on PARP Inhibitors in Ovarian Cancer', 'source': 'Targeted Oncology', 'date': 'Jun 16, 2023', 'snippet': 'Case: A 55-Year-Old Woman with BRCA-Mutated Ovarian Cancer. A 55-year-old \npresents to her PCP for heartburn and abdominal pain that started...', 'thumbnail': 'https://serpapi.com/searches/672406b648b9f7f4a84c72ac/images/6578c6e7c134720da622400024c443f050f3abcfbdae73ed96c5d9015adcd322.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6634000539779663}",,,,,,,,,,['neutral'],neutral,1 NCT03300947,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-39812-0', 'title': 'Improvement in OCD symptoms associated with serotoninergic psychedelics: a retrospective online survey', 'source': 'Nature', 'date': 'Aug 17, 2023', 'snippet': 'A renewed interest in the use of psychedelics for treating obsessive \ncompulsive disorder (OCD) has emerged in the last 20 years.', 'thumbnail': 'https://serpapi.com/searches/672406ba13e5d85abd9d796a/images/57bfc13080b9b71562cf99e3754415e822d8acc1c41c27312005ee520a666478.png', 'sentiment': 'positive', 'sentiment_prob': 0.597964346408844}",,,,,,,,,,['positive'],positive,1 NCT04681833,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00291-2/fulltext', 'title': 'Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape', 'source': 'The Lancet', 'date': 'Aug 8, 2022', 'snippet': 'A study to evaluate the safety and efficacy of mRNA-1345 vaccine targeting \nrespiratory syncytial virus (RSV) in adults ≥60 years of age.', 'thumbnail': 'https://serpapi.com/searches/672406df54163de37cb7c2e2/images/c2bc12b26d7d146e8a8415d8639765b99418e3e01eabb047d95ddaa675470dbd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8734835982322693}",,,,,,,,,,['neutral'],neutral,1 NCT04663737,"{'position': 1, 'link': 'https://www.nature.com/articles/s12276-023-01062-5', 'title': 'SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways', 'source': 'Nature', 'date': 'Aug 1, 2023', 'snippet': 'Solute carrier family 39 member 10 (SLC39A10) belongs to a subfamily of \nzinc transporters and plays a key role in B-cell development.', 'thumbnail': 'https://serpapi.com/searches/672406e18d0417f53161710d/images/497bc56597d897271bd670f2c0f50dcd0644899aeaf646201b8e00eec0a26e9d.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5658173561096191}",,,,,,,,,,['negative'],negative,0 NCT05074498,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/signs-alzheimers-reversed-eased-after-3-months-tb006/', 'title': '3 months of TB006 eased, reversed signs of Alzheimer’s disease: Trial', 'source': ""Alzheimer's News Today"", 'date': 'Apr 21, 2023', 'snippet': ""Nearly half the Alzheimer's disease patients treated with TrueBinding's \ninvestigational therapy TB006 showed cognitive improvement signs."", 'thumbnail': 'https://serpapi.com/searches/672406f75ed3ca4f9d3c285d/images/573716688d805d03171db61d0bd54288790b088f41ad7e17eecd5acf3eabb5cb.png', 'sentiment': 'positive', 'sentiment_prob': 0.5443678498268127}",,,,,,,,,,['positive'],positive,1 NCT03754309,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-023-00992-4', 'title': 'The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment', 'source': 'Nature', 'date': 'Mar 16, 2023', 'snippet': 'Atopic dermatitis (AD) is the most common inflammatory skin disease, and it \nis considered a complex and heterogeneous condition.', 'thumbnail': 'https://serpapi.com/searches/6724072b9936882cb5f0cf37/images/0f779b3d48893ee19e441e8f9e11ae7a5175540d96559a8e155a690acc273e51.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7401643991470337}",,,,,,,,,,['neutral'],neutral,1 NCT05355402,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2402309', 'title': 'Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk', 'source': 'The New England Journal of Medicine', 'date': 'Apr 7, 2024', 'snippet': 'Reducing the levels of triglycerides and triglyceride-rich lipoproteins \nremains an unmet clinical need. Olezarsen is an antisense...', 'thumbnail': 'https://serpapi.com/searches/6724072f3ad34db6ba164d1d/images/f092e5bf3e01c4fb5cc17904ffaccbbba84a0995c2b2e3d01043c24391a80793.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5698548555374146}",,,,,,,,,,['negative'],negative,0 NCT04368728,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2110345', 'title': 'Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months', 'source': 'The New England Journal of Medicine', 'date': 'Sep 15, 2021', 'snippet': 'BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA \nvaccine encoding a prefusion-stabilized, membrane-anchored severe acute...', 'thumbnail': 'https://serpapi.com/searches/67240735657c66db78be63b0/images/3cb5adb4f7be2f46c5f8c793eb43ba5ca13760935ea15779f863dfa9cd9712fd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8851207494735718}","{'position': 2, 'link': 'https://www.nature.com/articles/s41586-020-2798-3', 'title': 'SARS-CoV-2 vaccines in development', 'source': 'Nature', 'date': 'Sep 23, 2020', 'snippet': 'A phase I trial started in March 2020 and there are currently more than 180 \nvaccines at various stages of development.', 'thumbnail': 'https://serpapi.com/searches/67240735657c66db78be63b0/images/3cb5adb4f7be2f4635d861936d2744747db88598e760b3fd1cda2f760a310d63.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8990486264228821}","{'position': 3, 'link': 'https://www.thelancet.com/article/S0140-6736(20)32137-1/fulltext', 'title': 'SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates', 'source': 'The Lancet', 'date': 'Dec 29, 2020', 'snippet': 'In this Review, we discuss what is currently known about human humoral and \ncellular immune responses to severe acute respiratory syndrome coronavirus 2', 'thumbnail': 'https://serpapi.com/searches/67240735657c66db78be63b0/images/3cb5adb4f7be2f462bff94946e5f9db1dba15e05d506cba1c89add9a2a257d22.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'SCD411 has equivalent efficacy compared with reference aflibercept in \npatients with neovascular age-related macular degeneration and has a \ncomparable safety...', 'thumbnail': 'https://serpapi.com/searches/672407448de63c1a678fffa9/images/4eda15e2a01e811f22a6d4f3300917dd23ee1d4ea9cdeda32f92fac9ebbedc88.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6794275641441345}",,,,,,,,,,['neutral'],neutral,1 NCT05925647,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223017687', 'title': 'Boosting the therapeutic potential of cell secretome against osteoarthritis: Comparison of cytokine-based priming strategies', 'source': 'ScienceDirect.com', 'date': 'Dec 2, 2023', 'snippet': 'The secretome, or conditioned medium (CM), from Mesenchymal Stem/stromal \nCells (MSCs) has recently emerged as a promising cell-free therapeutic \nagainst...', 'thumbnail': 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'snippet': 'The FDA has approved just the second treatment for uncomplicated urinary \ntract infections (UTIs) in the last 2 decades.', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d0951a17d9222d0f2045c02a8c1015e372b8a42b9017f8b5d4e3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6426243782043457}","{'position': 2, 'link': 'https://www.drugtopics.com/view/breaking-fda-approves-moderna-s-mrna-rsv-vaccine-mresvia', 'title': 'Breaking: FDA Approves Moderna’s mRNA RSV Vaccine, mRESVIA', 'source': 'Drug Topics', 'date': 'May 31, 2024', 'snippet': 'The FDA has approved mRESVIA (mRNA-1345) an mRNA respiratory syncytial \nvirus (RSV) vaccine for adults aged 60 years and older to protect against \nlower...', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d0953a3e3b107901f67f123ac6c82e5ab966ba79284e2e1814d9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7456569671630859}","{'position': 3, 'link': 'https://www.drugtopics.com/view/small-doses-october-21-to-october-25', 'title': 'Small Doses: October 21 to October 25', 'source': 'Drug Topics', 'date': '5 days ago', 'snippet': ""The FDA has approved Iterum Therapeutics' sulopenem etzadroxil and \nprobenecid (Orlynvah) for the treatment of uUTIs in adult women who have..."", 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d0953ca5a7f0b30a38e3b91f777eb0749d666dc7bdb3d027d160.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.84382164478302}","{'position': 4, 'link': 'https://www.drugtopics.com/view/discussing-the-fda-panel-s-rejection-of-mdma-assisted-therapy-for-ptsd', 'title': 'Discussing the FDA Panel’s Rejection of MDMA-Assisted Therapy for PTSD', 'source': 'Drug Topics', 'date': 'Jun 10, 2024', 'snippet': 'The Psychopharmacologic Drugs Advisory Committee voted against the use of \nmidomafetamine (MDMA)-assisted therapy to treat post-traumatic stress \ndisorder (PTSD).', 'thumbnail': 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'snippet': 'The FDA approved ensifentrine (Ohtuvayre) for the maintenance treatment of \nchronic obstructive pulmonary disease (COPD) in adult patients,...', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d0951a3883925f22fca93904eb339bc6b85f94583b7ae5286a0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8896152973175049}","{'position': 7, 'link': 'https://www.drugtopics.com/view/majority-of-infants-in-icu-for-rsv-have-no-underlying-health-conditions', 'title': 'Majority of Infants in ICU for RSV Have No Underlying Health Conditions', 'source': 'Drug Topics', 'date': 'Aug 21, 2023', 'snippet': 'A recent study found that Infants younger than 3 months, those born \nprematurely, and those who were publicly insured were at a higher risk...', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d095a02d10c2eea53ffdabe0c029f45658ef85ca1e0f607d740f.jpeg', 'sentiment': 'negative', 'sentiment_prob': 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needed standard \nflow oxygen, HFNC, NIV, and ICU admission than the patients with...', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d095bf7e07b821437a874bac23082dab901eec2ca6ee011e61e4.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5299963355064392}","{'position': 10, 'link': 'https://www.drugtopics.com/view/shingles-on-the-face-complications-and-treatment', 'title': 'Shingles On the Face: Complications and Treatment', 'source': 'Drug Topics', 'date': 'Aug 3, 2021', 'snippet': 'The patient is at risk for potentially serious complications like facial \npain, numbness, tingling, or paralysis; damage to the eyes, and hair loss.', 'thumbnail': 'https://serpapi.com/searches/672407c435853912625195f5/images/6879bbc0ffa6d095b9f8eef5dcec717935c5b63a7b32745668e34e1c4caa9900.png', 'sentiment': 'negative', 'sentiment_prob': 0.7037845849990845}","['neutral', 'neutral', 'neutral', 'negative', 'neutral', 'neutral', 'negative', 'neutral', 'negative', 'negative']",neutral,1 NCT04536688,"{'position': 1, 'link': 'https://www.biospace.com/regulus-therapeutics-announces-top-line-data-from-the-first-cohort-of-phase-1b-clinical-trial-of-rgls4326-for-the-treatment-of-patients-with-autosomal-dominant-polycystic-kidney-disease-adpkd', 'title': 'Regulus Therapeutics Announces Top-Line Data from the First Cohort of Phase 1b Clinical Trial of RGLS4326 for the Treatment of Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)', 'source': 'BioSpace', 'date': 'May 3, 2021', 'snippet': 'Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company \nfocused on the discovery and development of innovative medicines targeting \nmicroRNAs.', 'thumbnail': 'https://serpapi.com/searches/672407d7fda26d2cf83e96ad/images/8b5680b6e72a67ec32fac50096907f86500c22f941007b9338a5a1a410e8ece6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8504105806350708}",,,,,,,,,,['neutral'],neutral,1 NCT03828617,"{'position': 1, 'link': 'https://www.pfizer.com/sites/default/files/investors/financial_reports/annual_reports/2021/story/new-data-to-support-vaccination-adherence/', 'title': 'Top-line study results support potential for co-administration of PREVNAR 20™ and seasonal flu vaccine in single appointment in line with CDC guidance', 'source': 'Pfizer', 'date': 'Mar 19, 2022', 'snippet': 'Top-line results from a phase 3 clinical trial we conducted demonstrated \nthat PREVNAR 20™ (Pneumococcal 20-valent Conjugate Vaccine) and a \nseasonal...', 'thumbnail': 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effective for some CAD patients in Phase 2 trial', 'source': 'Cold Agglutinin Disease News', 'date': '1 week ago', 'snippet': ""About half of the cold agglutinin disease patients in a small Phase 2 trial \nresponded to Incyte's experimental oral therapy parsaclisib."", 'thumbnail': 'https://serpapi.com/searches/6724088f17a2e29b4744d695/images/7e3b9a899e84d5cda3bf3e51925eda9770687e0f99c39573176a6f4b50c63f52.png', 'sentiment': 'positive', 'sentiment_prob': 0.6235363483428955}",,,,,,,,,,['positive'],positive,1 NCT02926898,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Fenfluramine%20%20%28Fintepla%29', 'title': 'Fenfluramine (Fintepla)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Dravet Syndrome, A Study to Evaluate Safety, Tolerability, and \nPharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to \nLess...', 'thumbnail': 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'https://virologyj.biomedcentral.com/articles/10.1186/s12985-021-01630-z', 'title': 'Efficacy and safety of oncolytic viruses in advanced or metastatic cancer: a network meta-analysis', 'source': 'Virology Journal', 'date': 'Jul 31, 2021', 'snippet': 'Oncolytic viruses (OVs) have shown prospects in advanced and metastatic \ncancer, and many clinical trials have been carried out.', 'thumbnail': 'https://serpapi.com/searches/672408a1861b9d63abef89ff/images/4c8bc1493a2312e592fd6322d8fa8eb8a75ab75d69b15e1da4acb4ebfb0b873c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8832862377166748}",,,,,,,,,,['neutral'],neutral,1 NCT06141889,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/with-170m-bioage-joins-lilly-in-oral-muscle-preserving-obesity-treatment/', 'title': 'With $170M, BioAge Joins Lilly in Oral, Muscle Preserving Obesity Treatment', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Feb 15, 2024', 'snippet': 'BioAge Labs has completed an oversubscribed $170 million Series D \nfinancing, the proceeds of which will support Phase II trials of a \ntherapy...', 'thumbnail': 'https://serpapi.com/searches/672408b424296a895db7ac56/images/488e081705331bb5e6bca6b4b69d06006582e3051a0bd0997eafb1d60f35b078.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6264560222625732}",,,,,,,,,,['neutral'],neutral,1 NCT02144714,"{'position': 1, 'link': 'https://juvenilearthritisnews.com/2018/10/19/imraldi-humira-biosimilar-now-available-eu-ja-other-conditions/', 'title': 'Imraldi, BioSimilar to Humira, Now Available in Europe to Treat JIA, Other Conditions', 'source': 'Juvenile Arthritis News', 'date': 'Oct 19, 2018', 'snippet': 'Imraldi, an adalimumab biosimilar to Humira, will now be available in the \nEuropean Union for the treatment of juvenile arthritis and other...', 'thumbnail': 'https://serpapi.com/searches/672408cdd1691523570522ff/images/52c1235ee7549ffb1dae31b409e975c154e1274a0fc877335371849721e88d52.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8594298958778381}",,,,,,,,,,['neutral'],neutral,1 NCT03361748,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2024850', 'title': 'Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'Feb 24, 2021', 'snippet': 'Idecabtagene vicleucel (ide-cel, also called bb2121) showed promising \nefficacy in a phase 1 study involving patients with relapsed or refractory \nmyeloma.', 'thumbnail': 'https://serpapi.com/searches/672409252a7727e9d2444000/images/0894aa7d84f6fd179976ac601d5b297157b184a40284cc09bda2f260379f51ce.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7197477221488953}","{'position': 2, 'link': 'https://www.nature.com/articles/s41408-021-00507-2', 'title': 'KarMMa-RW: comparison of idecabtagene vicleucel with real-world outcomes in relapsed and refractory multiple myeloma', 'source': 'Nature', 'date': 'Jun 18, 2021', 'snippet': 'This study demonstrated that ide-cel significantly improved responses and \nsurvival compared with currently available therapies in triple-class \nexposed RRMM.', 'thumbnail': 'https://serpapi.com/searches/672409252a7727e9d2444000/images/0894aa7d84f6fd176179b316cbd74e655da2f24c0fb546a6b9e107bfcc832a29.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6598561406135559}","{'position': 3, 'link': 'https://www.ajmc.com/view/ash-abstracts-reveal-disparate-car-t-cell-therapy-access-and-outcomes-in-mm-dlbcl', 'title': 'ASH Abstracts Reveal Disparate CAR T-Cell Therapy Access and Outcomes in MM, DLBCL', 'source': 'AJMC', 'date': 'Jan 7, 2023', 'snippet': 'Access to and outcomes of chimeric antigen receptor (CAR) T-cell therapies \nmay differ by characteristics such as race, ethnicity, gender,...', 'thumbnail': 'https://serpapi.com/searches/672409252a7727e9d2444000/images/0894aa7d84f6fd1706e2fd6f264c4fbfa653584b12cfb7ffff03b9ff713e0de4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.696790874004364}","{'position': 4, 'link': 'https://www.ajmc.com/view/ash-2022-car-t-cell-therapy', 'title': 'ASH 2022: CAR T-Cell Therapy', 'source': 'AJMC', 'date': 'Feb 5, 2023', 'snippet': 'Investigators detailed patient and financial outcomes associated with \nchimeric antigen receptor (CAR) T-cell therapies vs standard of care (SOC) \nfor treatment...', 'thumbnail': 'https://serpapi.com/searches/672409252a7727e9d2444000/images/0894aa7d84f6fd174490878e4603bdfa82184f38ade7fef422014d373ff788fa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9080037474632263}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT05082051,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/cdx-7108-shows-promise-epi-common-symptom-phase-1-trial/', 'title': 'CDX-7108 shows promise for EPI, common CF symptom, in Phase 1...', 'source': 'Cystic Fibrosis News Today', 'date': 'Feb 27, 2023', 'snippet': 'CDX-7108, an experimental treatment for exocrine pancreatic insufficiency, \nmay safely boost fat absorption in CF, according to trial data.', 'thumbnail': 'https://serpapi.com/searches/6724092cce1e10a40aec6225/images/1f7178e7a0404e862aab07d471a54c466cb40879f09045ccfd861fc3072837b8.png', 'sentiment': 'positive', 'sentiment_prob': 0.7909238338470459}",,,,,,,,,,['positive'],positive,1 NCT04196491,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02496-0', 'title': 'Idecabtagene vicleucel for relapsed and refractory multiple myeloma: post hoc 18-month follow-up of a phase 1 trial', 'source': 'Nature', 'date': 'Aug 17, 2023', 'snippet': 'Idecabtagene vicleucel (ide-cel) is a B-cell-maturation antigen \n(BCMA)-directed chimeric antigen receptor T cell therapy.', 'thumbnail': 'https://serpapi.com/searches/6724093621b01bfe86d64afb/images/d1ff65a19f8cdfdc03d09babc77b4b8129bf6ab05f8200b2e7924a08335b8325.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9099538326263428}",,,,,,,,,,['neutral'],neutral,1 NCT01283516,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1311107', 'title': 'Ceritinib in ALK -Rearranged Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jan 25, 2017', 'snippet': 'Non–small-cell lung cancer (NSCLC) harboring the anaplastic lymphoma kinase \ngene (ALK) rearrangement is sensitive to the ALK inhibitor crizotinib,...', 'thumbnail': 'https://serpapi.com/searches/672409908b7ba7dc1574cdac/images/1822ee99e267911f8a86a5561cf7a7485e4e60c5744422cc6488c323a2cd2f63.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6633459329605103}",,,,,,,,,,['neutral'],neutral,1 NCT02631044,"{'position': 1, 'link': 'https://www.onclive.com/view/subgroup-analysis-makes-the-case-for-earlier-liso-cel-administration-in-r-r-mcl', 'title': 'Subgroup Analysis Makes the Case for Earlier Liso-Cel Administration in R/R MCL', 'source': 'OncLive', 'date': 'Aug 13, 2024', 'snippet': 'Manali Kamdar, MD, discusses responses with liso-cel according to prior \nlines of therapy and BTK inhibitor exposure in mantle cell lymphoma.', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f44a0dd89a5178545ee2112229307a3c3d0c6eb9c1ca8c014.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9156875610351562}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/liso-cel-may-show-benefit-in-earlier-therapy-lines-for-lymphoma-subgroups', 'title': 'Liso-cel May Show Benefit in Earlier Therapy Lines for Lymphoma Subgroups', 'source': 'Cancer Network', 'date': 'Jun 14, 2024', 'snippet': 'Investigators must continue to explore the space for lisocabtagene \nmaraleucel in mantle cell lymphoma, according to Manali Kamdar, MD.', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1fccec4e224cd9c14e163b22baf5c1a4b4c1826c37eb0454d7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7087181210517883}","{'position': 3, 'link': 'https://www.cgtlive.com/view/wang-liso-cel-approval-mantle-cell-lymphoma', 'title': ""Michael Wang, MD, on Liso-Cel's Approval in Mantle Cell Lymphoma"", 'source': 'CGTLive®', 'date': 'Jun 6, 2024', 'snippet': 'The professor in the Department of Lymphoma/Myeloma at MD Anderson Cancer \nCenter discussed the advantages the newly approved CAR-T has for...', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f76cb0f752d656cd854c2c3c65346847f1d33b7ca458436e5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7924081087112427}","{'position': 4, 'link': 'https://www.onclive.com/view/liso-cel-elicits-clinically-meaningful-activity-in-heavily-pretreated-relapsed-refractory-mcl', 'title': 'Liso-Cel Elicits Clinically Meaningful Activity in Heavily Pretreated, Relapsed/Refractory MCL', 'source': 'OncLive', 'date': 'Jun 20, 2024', 'snippet': 'Liso-cel demonstrated clinically meaningful activity regardless of the \nnumber of previous lines of systemic therapy or response to prior BTK...', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1fb35868f228b8f85d6a48936c0172d35ab3a21f9e20e54924.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8159653544425964}","{'position': 5, 'link': 'https://immuno-oncologynews.com/2021/02/10/car-t-cell-therapy-breyanzi-approved-large-b-cell-lymphomas/', 'title': 'CAR T-cell Therapy Breyanzi Approved for Large B-cell Lymphomas', 'source': 'Immuno-Oncology News', 'date': 'Feb 10, 2021', 'snippet': 'The US Food and Drug Administration (FDA) has approved the CAR T-cell \ntherapy Breyanzi (lisocabtagene maraleucel) for treating adults with \nrelapsed or...', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f48a78ccc552c139bcd15309bccc5f6b0c8c52ab1ef1ef40c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8064560890197754}","{'position': 6, 'link': 'https://lymphomanewstoday.com/2020/01/07/potential-lymphoma-therapy-liso-cel-submitted-for-fda-approval/', 'title': 'Bristol-Myers Seeks FDA Approval of CAR T-cell Therapy Liso-Cel for Aggressive Large B-cell Lymphomas', 'source': 'Lymphoma News Today', 'date': 'Jan 7, 2020', 'snippet': 'Bristol-Myers Squibb has asked the US Food and Drug Administration (FDA) to \napprove its investigational CAR T-cell therapy lisocabtagene maraleucel \n(liso-cel)...', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f5d3e16cffed8c74406d16fc63aee5d36f3bb732a6427bc12.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9084925651550293}","{'position': 7, 'link': 'https://www.onclive.com/view/lisocabtagene-maraleucel-in-r-r-mcl-primary-analysis-results-from-the-mcl-cohort-of-the-single-arm-multicenter-seamless-design-transcend-nhl-001-study', 'title': 'Lisocabtagene Maraleucel in R/R MCL: Primary Analysis Results from the MCL Cohort of the Single-Arm, Multicenter, Seamless Design TRANSCEND NHL 001 Study', 'source': 'OncLive', 'date': 'Dec 5, 2023', 'snippet': 'Alexey Danilov, MD, PhD, reviews data from the TRANSCEND NHL 001 study \ninvestigating lisocabtagene maraleucel in patients with...', 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f6dbd9389aee088011de0d6a06893b7134bbe919bdc511156.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9374514222145081}","{'position': 8, 'link': 'https://www.onclive.com/view/patient-prioritization-is-the-foundation-for-a-successful-neurologic-oncology-career-with-d-ross-camidge-md-phd-and-douglas-ney-md', 'title': 'Patient Prioritization Is the Foundation for a Successful Neurologic Oncology Career: With D. Ross Camidge, MD, PhD; and Douglas Ney, MD', 'source': 'OncLive', 'date': '1 week ago', 'snippet': ""Drs Camidge and Ney discuss Dr Ney's journey to becoming a neurologic \noncologist and his experience as a physician with Tourette syndrome."", 'thumbnail': 'https://serpapi.com/searches/672409ddfcd69e091e955ab4/images/4d13f06767571e1f51dd0b3f38292fe27e5d3c24e33c4a9811d96751996d8ef9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6013492345809937}",,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04338958,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-023-01979-w', 'title': 'The JAK1/2 inhibitor ruxolitinib in patients with COVID-19 triggered hyperinflammation: the RuxCoFlam trial', 'source': 'Nature', 'date': 'Jul 28, 2023', 'snippet': 'Dysregulated hyperinflammatory response is key in the pathogenesis in \npatients with severe COVID-19 leading to acute respiratory distress...', 'thumbnail': 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'date': 'Mar 12, 2019', 'snippet': 'PURPOSERadiotherapy (RT) plus long-term androgen suppression (AS) are a \nstandard treatment option for patients with high-risk localized...', 'thumbnail': 'https://serpapi.com/searches/67240982dc969faceef7c216/images/246ff694216108ecbaacdd38749df9f326c5d3c82589e15fb28ed21740eb21b9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9201226234436035}",,,,,,,,,,['neutral'],neutral,1 NCT02292238,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/45m-grant-funds-trial-benfotiamine-vitamin-b1-precursor-cognitive-decline/', 'title': '$45M Grant Funds Trial of Vitamin B1 Precursor for Cognitive Decline', 'source': ""Alzheimer's News Today"", 'date': 'Jul 14, 2022', 'snippet': ""A clinical trial was given a $45-million NIH grant to test benfotiamine, a \nprecursor of thiamine, for slowing Alzheimer's cognitive decline."", 'thumbnail': 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(NASDAQ: ARWR) announced today that it has \ngained rights to ARO-PNPLA3, formerly called JNJ-75220795,...', 'thumbnail': 'https://serpapi.com/searches/672409de81262ade2810abbc/images/4c589304a73e86e93977af81995f8e5dbd654f92e6f1f64a44126683ec33e10c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7633824348449707}",,,,,,,,,,['neutral'],neutral,1 NCT00927836,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/strokeaha.113.001531', 'title': 'Granulocyte Colony–Stimulating Factor in Patients With Acute Ischemic Stroke:', 'source': 'American Heart Association Journals', 'date': 'Aug 20, 2013', 'snippet': 'Background and Purpose—Granulocyte colony–stimulating factor (G-CSF; AX200; \nFilgrastim) is a stroke drug candidate with excellent...', 'thumbnail': 'https://serpapi.com/searches/672409e064f11d07486b2679/images/2e36a35034773208f43e4353f80ede6e0a04edb718df2ba6ea38b535ff54a412.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7083484530448914}",,,,,,,,,,['neutral'],neutral,1 NCT04660643,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/tirzepatide-demonstrated-significant-and-superior-weight-loss-compared-to-placebo-in-two-pivotal-studies-301887287.html', 'title': 'Tirzepatide demonstrated significant and superior weight loss compared to placebo in two pivotal studies', 'source': 'PR Newswire', 'date': 'Jul 27, 2023', 'snippet': 'PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) announced results of two \nphase 3 tirzepatide studies in adults with obesity or overweight...', 'thumbnail': 'https://serpapi.com/searches/672409e4f8b05d9ece9f13dd/images/11259507ec07782cc8fa3e79edac4bfe8fb715341855e44b0239ea3a12e9f49c.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6481562852859497}",,,,,,,,,,['positive'],positive,1 NCT04819776,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/iloperidone-benefits-patients-with-bipolar-i-disorder-in-phase-3-trial/', 'title': 'Iloperidone Benefits Patients With Bipolar I Disorder in Phase 3 Trial', 'source': 'Medical Professionals Reference', 'date': 'Dec 19, 2022', 'snippet': 'Iloperidone was associated with significant improvement in adults with \nbipolar I disorder, according to results from a phase 3 study.', 'thumbnail': 'https://serpapi.com/searches/672409ed0664c984116fdc2e/images/d059bf0f52e2e8ffe0c43384b9264cae29a41577a5de51529078b8ec7b92fa77.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7241905331611633}",,,,,,,,,,['positive'],positive,1 NCT01101035,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1710895', 'title': 'Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout', 'source': 'The New England Journal of Medicine', 'date': 'Mar 12, 2018', 'snippet': 'Cardiovascular risk is increased in patients with gout. We compared \ncardiovascular outcomes associated with febuxostat, a nonpurine xanthine...', 'thumbnail': 'https://serpapi.com/searches/672409fe81bab7b92fca17d0/images/3aba9bc48dd99b15567b72986afa24faa7d994d1c7537201e1999ccc4460f70e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6810529828071594}",,,,,,,,,,['neutral'],neutral,1 NCT04725877,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-024-00818-y', 'title': 'Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV—workshop report | npj Vaccines', 'source': 'Nature', 'date': 'Feb 21, 2024', 'snippet': 'The goal of this workshop was to review data on leading vaccine candidates \nand to discuss the best strategies for combining these approaches to \noptimize...', 'thumbnail': 'https://serpapi.com/searches/67240a0db4fe875869b7a179/images/d940fc65a24191b40e506796ab97cb68a0eef600a8c757730295144583d872ef.png', 'sentiment': 'neutral', 'sentiment_prob': 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'OncLive', 'date': 'Jul 25, 2024', 'snippet': 'Bintrafusp alfa showcased clinical activity in patients with recurrent or \nmetastatic cervical cancer with disease progression during or...', 'thumbnail': 'https://serpapi.com/searches/67240a1bc05eb54577d2384c/images/51225fcc3a4579dc3f53b216ad82fdc8a9850bc5119cf7d0e41891a45a777821.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9027925729751587}",,,,,,,,,,['neutral'],neutral,1 NCT03631706,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-021-00868-x', 'title': 'Emerging new therapeutic antibody derivatives for cancer treatment | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Feb 7, 2022', 'snippet': 'In this review, we summarize antibodies of various molecular types, \nantibody applications in cancer therapy, and details of clinical study \nadvances.', 'thumbnail': 'https://serpapi.com/searches/67240a1ff922f6c63082ee00/images/a40273889b31936216bc0216a1f8868a6b7965165b802474ec1d6222f48a6f78.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8890555500984192}",,,,,,,,,,['neutral'],neutral,1 NCT00326898,"{'position': 1, 'link': 'https://www.onclive.com/view/kim-1-demonstrates-potential-utility-as-a-biomarker-with-worse-dfs-outcomes-in-kim-1-high-rcc', 'title': 'KIM-1 Demonstrates Potential Utility as a Biomarker With Worse DFS Outcomes in KIM-1–High RCC', 'source': 'OncLive', 'date': 'Jul 21, 2024', 'snippet': 'A third prospective trial has shown that higher KIM-1 levels at baseline \nresult in worse disease-free survival (DFS) outcomes for patients with \nresected high-...', 'thumbnail': 'https://serpapi.com/searches/67240a35f9f904be4fe0a67b/images/678807e2f73649ceaeb02adc0e6a15e7f538e78c2e113020356e3bf7daab1180.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6850661039352417}",,,,,,,,,,['negative'],negative,0 NCT02926950,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1238399/full', 'title': 'Comparative safety of different sodium-glucose transporter 2 inhibitors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials', 'source': 'Frontiers', 'date': 'Feb 5, 2024', 'snippet': 'BackgroundsThe safety of different sodium-glucose transporter 2 (SGLT-2) \ninhibitors remains uncertain due to the lack of head-to-head comparisons.', 'thumbnail': 'https://serpapi.com/searches/67240a48ecf150501c764808/images/58002a8ec4fe44c6ae7b3632614885987ce3f0abd2f3e67ddca3b20092203b2f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8960149884223938}",,,,,,,,,,['neutral'],neutral,1 NCT03028441,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/niaid-sponsored-trial-experimental-chikungunya-vaccine-begins', 'title': 'NIAID-Sponsored Trial of Experimental Chikungunya Vaccine Begins', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jun 5, 2017', 'snippet': 'A clinical trial of an experimental vaccine to prevent infection with \nchikungunya virus is now enrolling healthy adult volunteers at three sites \nin the United...', 'thumbnail': 'https://serpapi.com/searches/67240a57b6a79c9a7bf4c1ef/images/736c69a0937e5004b2f3df4c303c2de8509edac4f20cb2b95fcfda22e1b37a7e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9215162992477417}",,,,,,,,,,['neutral'],neutral,1 NCT04317040,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20201123005593/en/Merck-to-Acquire-OncoImmune', 'title': 'Merck to Acquire OncoImmune', 'source': 'Business Wire', 'date': 'Nov 23, 2020', 'snippet': 'Merck will accelerate development of CD24Fc, a candidate for the treatment \nof patients with severe and critical COVID-19...', 'thumbnail': 'https://serpapi.com/searches/67240a5f48e668587c2366e4/images/1701f3bdc693cdf7503cbe65e73fd99a7a966f1f7e366b833f2232f085f5f930.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6530737280845642}",,,,,,,,,,['neutral'],neutral,1 NCT01733186,"{'position': 1, 'link': 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A pathway to clinical success', 'source': 'Nature', 'date': 'Apr 25, 2023', 'snippet': 'We evaluated 15 randomized controlled clinical trials (RCTs) and 11 \nnonrandomized RCTs using culture-expanded MSCs in the treatment of knee OA, \nand we found...', 'thumbnail': 'https://serpapi.com/searches/67240a6b2da15795533ddc95/images/7d4c7a6dae122b92f9cf31ebe3a2c73bedfb8f6e7b1427718bf6ba6c3c9d08e5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8233572840690613}",,,,,,,,,,['neutral'],neutral,1 NCT04927065,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02517-y', 'title': 'Original SARS-CoV-2 monovalent and Omicron BA.4/BA.5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results', 'source': 'Nature', 'date': 'Aug 31, 2023', 'snippet': 'This ongoing, open-label, phase 2/3 trial compared the safety and \nimmunogenicity of the Omicron BA.4/BA.5-containing bivalent mRNA-1273.222...', 'thumbnail': 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Medicine', 'date': 'Jan 26, 2022', 'snippet': 'Neutralization of the omicron variant was assessed in serum samples \nobtained from persons who had received an mRNA-1273 booster.', 'thumbnail': 'https://serpapi.com/searches/67240a988cf8aebaab22c965/images/5bfad3f4179328821e846cb1318fe8dc52edd026cfec248edfc0c3642bc1a801.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7621810436248779}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01204749,"{'position': 1, 'link': 'https://www.nature.com/articles/bjc2012541', 'title': 'Targeted anti-vascular therapies for ovarian cancer: current evidence', 'source': 'Nature', 'date': 'Feb 5, 2013', 'snippet': 'This review attempts to discuss progress to date in tackling a more general \ntarget applicable to ovary cancer—angiogenesis...', 'thumbnail': 'https://serpapi.com/searches/67240ab40e6db374244f6e96/images/ad29760b360d4b0b52724d826ec78c1d95d5c8ccc46e629854f2033d15a81b7e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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CX-5461 exhibits synthetic lethality in BRCA1-/BRCA2-deficient \ncells, it also causes extensive, nonselective, collateral mutagenesis in \nall three cell...', 'thumbnail': 'https://serpapi.com/searches/67240b25acf7f8b0d80cf6da/images/704c69d7a8407c95dd46ee66c54d6e947171d81dc7e4c42ac87546bedf3ff2dd.png', 'sentiment': 'negative', 'sentiment_prob': 0.7724517583847046}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-022-31199-2', 'title': 'Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies', 'source': 'Nature', 'date': 'Jun 24, 2022', 'snippet': 'CX-5461 is a G-quadruplex stabilizer that exhibits synthetic lethality in \nhomologous recombination-deficient models.', 'thumbnail': 'https://serpapi.com/searches/67240b25acf7f8b0d80cf6da/images/704c69d7a8407c95b4e7ba2a18eaf25df9b68f0ffa0ac19cce2a2e4493dbacf8.png', 'sentiment': 'negative', 'sentiment_prob': 0.6291135549545288}","{'position': 3, 'link': 'https://ovariancancernewstoday.com/2020/07/21/small-inhibitor-may-boost-effectiveness-of-parp-inhibitors-in-some-ovarian-cancers-mouse-study-finds/', 'title': 'Small Inhibitor May Boost Effectiveness of PARP Inhibitors in Some Ovarian Cancers, Mouse Study Finds', 'source': 'Ovarian Cancer News Today', 'date': 'Jul 21, 2020', 'snippet': 'A small inhibitor that prevents cells from making ribosomes may improve \nPARP inhibitor efficacy across ovarian cancers with mutations in DNA...', 'thumbnail': 'https://serpapi.com/searches/67240b25acf7f8b0d80cf6da/images/704c69d7a8407c9502624899283edea49fa3e83da97c3ec7133d176e9717da96.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.614351749420166}",,,,,,,,"['negative', 'negative', 'neutral']",negative,0 NCT00233324,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1208506', 'title': 'Neurodevelopmental Outcomes in the Early CPAP and Pulse Oximetry Trial', 'source': 'The New England Journal of Medicine', 'date': 'Dec 27, 2012', 'snippet': 'Previous results from our trial of early treatment with continuous positive \nairway pressure (CPAP) versus early surfactant treatment in...', 'thumbnail': 'https://serpapi.com/searches/67240b2a8a7c0972a22e3706/images/194fd90c445de0c1faca65c15a9f6671a0b69cadf24dbd1c9a05aa496bc90606.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9130668640136719}",,,,,,,,,,['neutral'],neutral,1 NCT03611751,"{'position': 1, 'link': 'https://www.thepharmaletter.com/biotechnology/2-9-billion-in-sales-forecast-for-bms-sotyktu-by-2029', 'title': '$2.9 billion in sales forecast for BMS’ Sotyktu by 2029', 'source': 'The Pharma Letter', 'date': 'May 11, 2023', 'snippet': ""$2.9 billion in sales forecast for BMS' Sotyktu by 2029. Biotechnology. 11 \nMay 2023. bristol_myers_squibb_shutterstock_large."", 'thumbnail': 'https://serpapi.com/searches/67240ade167793224537b7fb/images/adbfb6a36999c2329132239a2d3c3cac3571b5dfa3634a69b3164687c8a2738d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7873889207839966}","{'position': 2, 'link': 'https://www.empr.com/home/news/fda-approves-sotyktu-for-moderate-to-severe-plaque-psoriasis/', 'title': 'FDA Approves Sotyktu for Moderate to Severe Plaque Psoriasis', 'source': 'Medical Professionals Reference', 'date': 'Sep 12, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Sotyktu™ \n(deucravacitinib) for the treatment of adults with moderate to severe \nplaque...', 'thumbnail': 'https://serpapi.com/searches/67240ade167793224537b7fb/images/adbfb6a36999c23206b152fa72c5a6d2a1b8032258dd5656fdaa960e1e606a7c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7778393626213074}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02570308,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20180521006120/en/Immunocore-to-Present-New-Data-from-IMCgp100-102-Trial-in-Metastatic-Uveal-Melanoma-at-2018-ASCO-Annual-Meeting', 'title': 'Immunocore to Present New Data from IMCgp100-102 Trial in Metastatic Uveal Melanoma at 2018 ASCO Annual Meeting', 'source': 'Business Wire', 'date': 'May 22, 2018', 'snippet': 'OXFORD, United Kingdom & CONSHOHOCKEN, Pa.--(BUSINESS WIRE)--Immunocore \nLimited, a leading T cell receptor (TCR) company focused on...', 'thumbnail': 'https://serpapi.com/searches/67240af5acf7f8b0d80cf6cc/images/0916090242846d6644e608a5a4a5bec1ea30b57eb8e9328ef53d8c00b9b697b3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9128562211990356}",,,,,,,,,,['neutral'],neutral,1 NCT02588105,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0286-4', 'title': 'pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry', 'source': 'Nature', 'date': 'Nov 2, 2018', 'snippet': 'AZD0156 and AZD6738 are potent and selective inhibitors of \nataxia-telangiectasia-kinase (ATM) and ataxia-telangiectasia-mutated and...', 'thumbnail': 'https://serpapi.com/searches/67240b095bb6a2d5bbfd1709/images/3211434848e21f5150e49d90b3749d0bb6c387d6712de2758c71bdb54d521e59.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8375502228736877}","{'position': 2, 'link': 'https://news.cuanschutz.edu/cancer-center/irinotecan-breaks-cancer-cell-dna', 'title': 'Irinotecan breaks cancer cell DNA – AZD0156 keeps the body from repairing it', 'source': 'University of Colorado Anschutz Medical Campus', 'date': 'Apr 3, 2019', 'snippet': 'The chemotherapy drug irinotecan creates DNA damage leading to cell death \nand is used to treat colorectal cancer, among other cancer types.', 'thumbnail': 'https://serpapi.com/searches/67240b095bb6a2d5bbfd1709/images/3211434848e21f510f8c5541f8b6206e4a9b39ebc17db083d2eba3369de8dd4b.png', 'sentiment': 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V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients', 'source': 'Nature', 'date': 'Oct 1, 2019', 'snippet': 'V565 is an engineered TNFα-neutralising single domain antibody formulated \ninto enteric coated mini-tablets to enable release in the intestine after \noral...', 'thumbnail': 'https://serpapi.com/searches/67240b42a5aae957db43771c/images/c55bb2722445eb0e41c231656fdf8f6c5f9e42d30e5e5077e5771dbe0010fdd1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8417642712593079}",,,,,,,,,,['neutral'],neutral,1 NCT02308969,"{'position': 1, 'link': 'https://www.nature.com/articles/tp201754', 'title': 'Acute effects of LSD on amygdala activity during processing of fearful stimuli in healthy subjects', 'source': 'Nature', 'date': 'Apr 4, 2017', 'snippet': 'Lysergic acid diethylamide (LSD) induces profound changes in various mental \ndomains, including perception, self-awareness and emotions.', 'thumbnail': 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'https://multiplesclerosisnewstoday.com/news-posts/nervgen-completes-dosing-group-ms-candidate-nvg-291/', 'title': 'NervGen Completes Dosing Another Group With MS Candidate NVG-291', 'source': 'Multiple Sclerosis News Today', 'date': 'Nov 18, 2022', 'snippet': ""A Phase 1 trial testing NVG-291, NervGen Pharma's candidate for MS, has \ncompleted dosing in the final group of healthy postmenopausal women."", 'thumbnail': 'https://serpapi.com/searches/67240b675a461a844d4dccba/images/b9ec3d34cd92b8a68c5197f72bd9c017724665ebed0bee0c5a313506d63958d0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9050969481468201}",,,,,,,,,,['neutral'],neutral,1 NCT01437397,"{'position': 1, 'link': 'https://copdnewstoday.com/news/duaklir-available-copd-patients-us/', 'title': 'Duaklir Now Available to COPD Patients in the U.S.', 'source': 'COPD News Today', 'date': 'Oct 29, 2019', 'snippet': 'Duaklir is now available to patients with chronic obstructive pulmonary \ndisease (COPD) living in the U.S., Circassia Pharmaceuticals...', 'thumbnail': 'https://serpapi.com/searches/67240b6a6a5dd30cfdf5f9d3/images/8c1b6cbb5da6776ddc9894ce64b84cae6cf2e2810060b7716f20d636099069af.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7435298562049866}",,,,,,,,,,['neutral'],neutral,1 NCT03665285,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-13997-2', 'title': 'Prognostic value of PD-L1 and Siglec-15 expression in patients with nasopharyngeal carcinoma', 'source': 'Nature', 'date': 'Jun 21, 2022', 'snippet': 'Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) might be \ninvolved in the activation of important pathways related to tumor...', 'thumbnail': 'https://serpapi.com/searches/67240b73a324362e226c5cb7/images/eb5c4eb1a6b559f9c60e95125d04d4c810b1963fa2f6a7afd50c2a6fa532de3e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8968281149864197}",,,,,,,,,,['neutral'],neutral,1 NCT03588130,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/mediwound-reinforces-wound-therapy-escharex-data-ahead-of-phase-iii-trial/', 'title': 'MediWound reinforces wound therapy EscharEx data ahead of Phase III trial', 'source': 'Clinical Trials Arena', 'date': 'Jul 30, 2024', 'snippet': 'MediWound has published Phase II trial data showing that its wound \ndebridement therapy, EscharEx, is superior at treating venous leg ulcers \nthan other non-...', 'thumbnail': 'https://serpapi.com/searches/67240b8f7ca6b3ab4347d760/images/f0de7046fe5e75e842db3e8006253bd43d76dc8d37c753b46b081b06b4740037.png', 'sentiment': 'positive', 'sentiment_prob': 0.7243747711181641}",,,,,,,,,,['positive'],positive,1 NCT03399786,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2004215', 'title': 'Evinacumab for Homozygous Familial Hypercholesterolemia', 'source': 'The New England Journal of Medicine', 'date': 'Aug 19, 2020', 'snippet': 'Evinacumab, a monoclonal antibody against ANGPTL3, has shown potential \nbenefit in patients with homozygous familial hypercholesterolemia.', 'thumbnail': 'https://serpapi.com/searches/67240baeb6a79c9a7bf4c23b/images/9ff15079438ed670df7d53240fa46cd3d942ad1452ed977472eebf22de9cd39e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7179078459739685}",,,,,,,,,,['neutral'],neutral,1 NCT00634712,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0805450', 'title': 'Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction', 'source': 'The New England Journal of Medicine', 'date': 'May 1, 2018', 'snippet': 'Approximately 50% of patients with heart failure have a left ventricular \nejection fraction of at least 45%, but no therapies have been shown to \nimprove the...', 'thumbnail': 'https://serpapi.com/searches/67240bbf98d8de9a4cffa089/images/43bb73587daadab440417f01ba4be41bfb556396b2110b48fb5fa9e21b190897.png', 'sentiment': 'negative', 'sentiment_prob': 0.6149664521217346}",,,,,,,,,,['negative'],negative,0 NCT01935973,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-0199-6', 'title': 'Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence', 'source': 'Nature', 'date': 'Jul 29, 2020', 'snippet': 'Advanced and recurrent gynecological cancers are associated with poor \nprognosis and lack of effective treatment. The developments of the...', 'thumbnail': 'https://serpapi.com/searches/67240bc893584c2b705856e6/images/4b21a89701e72e1f57d4cd5870f36b217e780307db089b4b5ec2dfc1f3679e15.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6648945212364197}",,,,,,,,,,['neutral'],neutral,1 NCT02474290,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01614-1', 'title': 'Impact of genetic patterns on sorafenib efficacy in patients with FLT3-ITD acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation: a multi-center, cohort study', 'source': 'Nature', 'date': 'Sep 14, 2023', 'snippet': 'Sorafenib therapy improves overall survival (OS) in patients with FLT3 \ninternal tandem duplication (ITD) acute myeloid leukemia (AML)...', 'thumbnail': 'https://serpapi.com/searches/67240bcafcd69e0952237cad/images/fe98535e38d7d1abe1939fd4682372142a8589081dd5750c251735c4ced3c7b1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.673363983631134}",,,,,,,,,,['neutral'],neutral,1 NCT04242498,"{'position': 1, 'link': 'https://www.ajmc.com/view/bimekizumab-elicits-clinically-meaningful-responses-in-moderate-to-severe-hidradenitis-suppurativa', 'title': 'Bimekizumab Elicits Clinically Meaningful Responses in Moderate to Severe Hidradenitis Suppurativa', 'source': 'AJMC', 'date': 'May 24, 2024', 'snippet': 'In newly published findings from the pivotal phase 3 BE HEARD I \n(NCT04242446) and BE HEARD II (NCT04242498) trials, bimekizumab was well...', 'thumbnail': 'https://serpapi.com/searches/67240be6400bd5fea40fd58f/images/d17c06d7aa86505bbf371933d2565d41faebf11dc1cfecfcc6a62f86fe2a73b6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6742416024208069}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/phase-3-data-analysis-presented-at-eadv-2023-showed-bimekizumab-achieved-high-thresholds-of-clinical-response-in-hidradenitis-suppurativa-301955218.html', 'title': 'Phase 3 Data Analysis Presented at EADV 2023 Showed Bimekizumab Achieved High Thresholds of Clinical Response in Hidradenitis Suppurativa', 'source': 'PR Newswire', 'date': 'Oct 12, 2023', 'snippet': 'Bimekizumab treatment resulted in clinically meaningful improvements in \nHiSCR50 and the more stringent endpoints HiSCR75,...', 'thumbnail': 'https://serpapi.com/searches/67240be6400bd5fea40fd58f/images/d17c06d7aa86505be13c7a8c453101694f6c575530a4019345d671ed6b3cabd0.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6450156569480896}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT03697109,"{'position': 1, 'link': 'https://cushingsdiseasenews.com/news/significant-benefits-seen-relacorilant-trial-cushings-patients/', 'title': 'Relacorilant shows significant benefits in Cushing’s patients in trial', 'source': ""Cushing's Disease News"", 'date': 'Apr 24, 2024', 'snippet': ""Relacorilant treatment is being seen to reduce high blood pressure and \nblood sugar levels in Cushing's syndrome patients in a Phase 3 trial."", 'thumbnail': 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complete enrollment', 'source': ""Cushing's Disease News"", 'date': 'Mar 3, 2023', 'snippet': ""Enrollment is nearly complete for the GRACE Phase 3 trial testing \nrelacorilant in people with Cushing's syndrome due to any underlying..."", 'thumbnail': 'https://serpapi.com/searches/67240bf7c05eb54546b68afa/images/18dbca316189c28664b71311ed37fd7b8cdce74dd2363319df928e50b6fb43d4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7574314475059509}","{'position': 4, 'link': 'https://cushingsdiseasenews.com/news/corcept-attributes-revenue-boost-better-recognition/', 'title': 'Corcept attributes its revenue boost to better recognition of Cushing’s', 'source': ""Cushing's Disease News"", 'date': 'Nov 3, 2023', 'snippet': ""Corcept Therapeutics is expected to earn nearly $500 million this year, due \nto the increased awareness about Cushing's,..."", 'thumbnail': 'https://serpapi.com/searches/67240bf7c05eb54546b68afa/images/18dbca316189c28687bd763f8fb812eb4338110b48d2565c9a9adf4571f35e66.png', 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participants', 'source': ""Parkinson's News Today"", 'date': 'Mar 29, 2023', 'snippet': ""Athira Pharma is completing its Phase 2 clinical trial of the experimental \ntherapy fosgonimeton in people with Parkinson's disease dementia or \ndementia with..."", 'thumbnail': 'https://serpapi.com/searches/67240c34a5d702d2fbdaac4f/images/d32b218adce7211b37e703dd2357fd9969bf6a261f02d0dd71cbee585925b684.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8284434676170349}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/fosgonimeton-shows-potential-dementia-treatment-athira/', 'title': 'Fosgonimeton shows potential as dementia treatment, Athira says', 'source': ""Parkinson's News Today"", 'date': 'Mar 13, 2024', 'snippet': ""Data presented at a neurological diseases conference support fosgonimeton's \npotential to treat dementia in Parkinson's and Alzheimer's."", 'thumbnail': 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'title': 'A pivotal bridging study of lurbinectedin as second-line therapy in Chinese patients with small cell lung cancer', 'source': 'Nature', 'date': 'Feb 13, 2024', 'snippet': 'This single-arm, multi-center clinical trial aimed to evaluate the safety, \ntolerability, DLT, recommended dose (RD), preliminary efficacy,...', 'thumbnail': 'https://serpapi.com/searches/67240c4290b57c018e6f3afd/images/480bed35aeaa1e83cc51e42880c7cdc8a1ddae2eb44c2a5899cbc4edd5dc4980.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7706957459449768}",,,,,,,,,,['neutral'],neutral,1 NCT05325775,"{'position': 1, 'link': 'https://pharmaceutical-journal.com/article/feature/managing-menopause-treating-hot-flushes-without-hormones', 'title': 'Managing menopause: treating hot flushes without hormones', 'source': 'The Pharmaceutical Journal', 'date': 'Nov 17, 2022', 'snippet': ""A new class of drugs is in clinical trials — neurokinin 3 receptor (NK3R) \nantagonists, which act on the brain's thermoregulatory centres to..."", 'thumbnail': 'https://serpapi.com/searches/67240c4290b57c018e6f3afe/images/86d5c656b44521a484b45507e5fbc5b3a02028a0c00734b7dca935c2429b4e33.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8747931718826294}",,,,,,,,,,['neutral'],neutral,1 NCT05338099,"{'position': 1, 'link': 'https://www.cgtlive.com/view/genetic-medicine-in-dmd-end-points-assessment-and-approvals', 'title': 'Genetic Medicine in DMD: End Points, Assessment, and Approvals', 'source': 'CGTLive®', 'date': 'Jun 16, 2023', 'snippet': 'CGTLive takes a look at challenges that have beset the first gene therapy \ncoming close to market for treating Duchenne muscular dystrophy in 2023.', 'thumbnail': 'https://serpapi.com/searches/67240c49cc48795386827569/images/489edfe535dbcea160b78c48879228a8ba965caf44e94b494e4b4ed7b7d3883a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9204220771789551}",,,,,,,,,,['neutral'],neutral,1 NCT01548404,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1314768', 'title': 'Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 10, 2014', 'snippet': 'We performed randomized, double-blind, placebo-controlled trials involving \nadults who had moderate-to-severe atopic dermatitis despite treatment with \ntopical...', 'thumbnail': 'https://serpapi.com/searches/67240c4e98876dfdc6bb4a5c/images/b6793db9c20180b421869caf3f00b51e3ee188edd6d98ae7c9fffe5c3a5fe84f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8305745720863342}",,,,,,,,,,['neutral'],neutral,1 NCT00063206,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/randomized-double-blind-placebo-controlled-trial-desvenlafaxine/', 'title': 'A Randomized, Double-Blind, Placebo-Controlled Trial of Desvenlafaxine Succinate in Adult Outpatients With Major Depressive Disorder', 'source': 'Psychiatrist.com', 'date': 'Oct 21, 2023', 'snippet': 'This study evaluated the efficacy and tolerability of desvenlafaxine \nsuccinate (desvenlafaxine) in the treatment of major depressive disorder \n(MDD).', 'thumbnail': 'https://serpapi.com/searches/67240c60dda9d9effefd3292/images/840ac977cc8cbaa8415e603957199f692e7d089a47b2b4659a7bb8d1712965da.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8758249878883362}",,,,,,,,,,['neutral'],neutral,1 NCT05413161,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20240725869572/en/Kashiv-BioSciences-Announces-Completion-of-Enrollment-for-Phase-III-Clinical-Trial-of-ADL018-a-Biosimilar-Candidate-to-XOLAIR%C2%AE-omalizumab', 'title': 'Kashiv BioSciences Announces Completion of Enrollment for Phase III Clinical Trial of ADL018, a Biosimilar Candidate to XOLAIR® (omalizumab)', 'source': 'Business Wire', 'date': 'Jul 25, 2024', 'snippet': 'Kashiv BioSciences, LLC today announced the completion of patient \nenrollment for its Phase III clinical trial of ADL018, a biosimilar \ncandidate to XOLAIR®.', 'thumbnail': 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Cemiplimab, \nthe fully human programmed cell death 1 (PD-1)–blocking antibody...', 'thumbnail': 'https://serpapi.com/searches/67240cf3db3ac91c252ac325/images/bd5e32001c6706b6c7ac9c7007d8ba02e5f9bdb98d104334120d0d9c29f0a426.png', 'sentiment': 'negative', 'sentiment_prob': 0.8167092204093933}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/cemiplimab-as-second-line-monotherapy-confers-long-term-survival-benefit-in-recurrent-metastatic-cervical-cancer', 'title': 'Cemiplimab as Second-Line Monotherapy Confers Long-Term Survival Benefit in Recurrent/Metastatic Cervical Cancer', 'source': 'Cancer Network', 'date': 'Sep 10, 2022', 'snippet': 'Findings from long-term follow-up of the EMPOWER-Cervical 1 study \ndemonstrated that cemiplimab improved survival vs chemotherapy and...', 'thumbnail': 'https://serpapi.com/searches/67240cf3db3ac91c252ac325/images/bd5e32001c6706b6078d72fee7ea5e20523da106924e46daa080823fe669ea25.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7015032768249512}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT02469090,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/kynmobi-discontinued-us-canada-limited-use-sunovion/', 'title': 'Kynmobi to be discontinued in US and Canada due to limited use |...', 'source': ""Parkinson's News Today"", 'date': 'Jun 12, 2023', 'snippet': ""Kynmobi (apomorphine hydrochloride), an under-the-tongue therapy approved \nto help manage off episodes in Parkinson's disease, is being discontinued \nin the US..."", 'thumbnail': 'https://serpapi.com/searches/67240cfb4a4a1df3ffaf0675/images/6bd6fafa111b4d1e96b116188548c36f791c07514e4594dd2e3a5c4965851aca.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5540068745613098}",,,,,,,,,,['negative'],negative,0 NCT04279314,"{'position': 1, 'link': 'https://rettsyndromenews.com/news/long-term-daybue-led-continual-improvements-patients-data/', 'title': 'Long-term Daybue led to continual improvements in patients: Studies', 'source': 'Rett Syndrome News', 'date': 'Jul 24, 2024', 'snippet': 'Long-term treatment with Daybue (trofinetide) led to continual improvements \nin symptoms in people with Rett syndrome in extension studies,...', 'thumbnail': 'https://serpapi.com/searches/67240cf7bd7cf00dff1d5a9d/images/9789e79d4503fdad16d55d53ac06fabc3d27f7c09162e3fe4a30b0b3dfe2a4e2.png', 'sentiment': 'positive', 'sentiment_prob': 0.6373507380485535}",,,,,,,,,,['positive'],positive,1 NCT02729298,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.811247/full', 'title': 'The Development of AXL Inhibitors in Lung Cancer: Recent Progress and Challenges', 'source': 'Frontiers', 'date': 'Jun 28, 2023', 'snippet': 'AXL, along with MER and TYRO3, is a receptor tyrosine kinase from the TAM \nfamily. Although AXL itself is not thought to be a potent oncogenic \ndriver,...', 'thumbnail': 'https://serpapi.com/searches/67240d1b76585795dffb1f14/images/4d97b0f353f7688a5235ac7d5e980f36a538cd613ef8a3d228033d4e9c358ed6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9306911826133728}",,,,,,,,,,['neutral'],neutral,1 NCT04090684,"{'position': 1, 'link': 'https://alsnewstoday.com/news/als-combination-therapy-primec-receives-fdas-orphan-drug-designation-enters-clinical-trials/', 'title': ""ALS Combo Therapy PrimeC Granted FDA's Orphan Drug Status"", 'source': 'ALS News Today', 'date': 'Feb 12, 2020', 'snippet': 'PrimeC, a combination treatment by NeuroSense Therapeutics to slow down or \nhalt the progression of ALS, has received orphan drug status from...', 'thumbnail': 'https://serpapi.com/searches/67240c852c83d5b81af4c39e/images/08a8fd8bcec5ec0bdd8ccc833c6e2d5dddd59f7245eb71983b35a9ff8813f8fb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8949474096298218}",,,,,,,,,,['neutral'],neutral,1 NCT02401347,"{'position': 1, 'link': 'https://www.nature.com/articles/s43018-022-00439-1', 'title': 'A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes', 'source': 'Nature', 'date': 'Oct 17, 2022', 'snippet': 'Talazoparib, a PARP inhibitor, is active in germline BRCA1 and BRCA2 \n(gBRCA1/2)-mutant advanced breast cancer, but its activity beyond...', 'thumbnail': 'https://serpapi.com/searches/67240c92310300962cf1b322/images/b1effafb884a5c42d1da1f9bf21b9a416dfdef2abb63c5d08805e1872b768425.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8995737433433533}",,,,,,,,,,['neutral'],neutral,1 NCT04030026,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/trevi-therapeutics-to-present-final-data-from-phase-2-trial-of-oral-nalbuphine-extended-release-for-chronic-cough-in-ipf-at-bts-winter-meeting-301660829.html', 'title': ""Trevi Therapeutics to Present Final Data from Phase 2 Trial of Oral Nalbuphine Extended Release for Chronic Cough in IPF at BTS' Winter Meeting"", 'source': 'PR Newswire', 'date': 'Oct 27, 2022', 'snippet': 'PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage \nbiopharmaceutical company developing an investigational therapy...', 'thumbnail': 'https://serpapi.com/searches/67240c93ce1e10a40aec62f0/images/0b96ed3fc020bc3ad6938aefc83abcfcf28778ce18f69024f1db0cec1ab1946e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9143315553665161}",,,,,,,,,,['neutral'],neutral,1 NCT01640067,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-019-1582-5', 'title': 'Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats | Cell Death & Disease', 'source': 'Nature', 'date': 'Apr 25, 2019', 'snippet': 'Stem cells are emerging as a therapeutic option for incurable diseases, \nsuch as Amyotrophic Lateral Sclerosis (ALS).', 'thumbnail': 'https://serpapi.com/searches/67240c94f6aa534e9217e9a8/images/580c29a86b18194fd52a488bf4cd98c6281ee9b966197e2cc9fa8b80ded25284.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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outcomes with first-line Versamune HPV plus \npembrolizumab in HPV16–positive recurrent or metastatic HNSCC.', 'thumbnail': 'https://serpapi.com/searches/67240cb9272a8712a14a4efb/images/8fa4a7bdd884cf8e7093900ee39b7e82ff4631f4a6d43019c4043a32f195cf76.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9437682032585144}",,,,,,,,,,['neutral'],neutral,1 NCT03922308,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/news/ittp-thrombotic-purpura-recombitant-adamtd13-clinical-promise-treatment-risk/', 'title': 'Recombinant ADAMTS13 Shows Clinical Promise in iTTP', 'source': 'Hematology Advisor', 'date': 'Jul 6, 2023', 'snippet': 'Recombinant ADAMTS13 (rADAMTS13) appears to confer clinical benefit to \npatients with immune-mediated thrombotic thrombocytopenic purpura (iTTP), \naccording to...', 'thumbnail': 'https://serpapi.com/searches/67240cc15ddfba8fdaa1fc0d/images/769c77fd47bb54b641221461c743bc7672210c4b385302c5bbe663f72e01fa17.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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\nefficacy and safety of posaconazole as compared with the efficacy and \nsafety of...', 'thumbnail': 'https://serpapi.com/searches/67240d30b4b72d05f511ffb8/images/d4fe81c206f85e6fe4b1508fc3c2210c4c5bcfbb48174754df6d5c69cf4784e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8674216866493225}",,,,,,,,,,['neutral'],neutral,1 NCT03926117,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/ziltivekimab-reduced-inflammatory-biomarkers-associated-with-atherosclerosis-in-people-with-chronic-kidney-disease-in-phase-2-trial-301292574.html', 'title': 'Ziltivekimab reduced inflammatory biomarkers associated with atherosclerosis in people with chronic kidney disease in phase 2 trial', 'source': 'PR Newswire', 'date': 'May 17, 2021', 'snippet': 'PRNewswire/ -- Novo Nordisk today presented results from RESCUE, a phase 2 \nrandomised, double-blind, placebo controlled clinical trial...', 'thumbnail': 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'https://www.sciencedirect.com/science/article/pii/S0264410X20313712', 'title': 'The respiratory syncytial virus fusion protein-specific B cell receptor repertoire reshaped by post-fusion subunit vaccination', 'source': 'ScienceDirect.com', 'date': 'Nov 25, 2020', 'snippet': 'Respiratory syncytial virus (RSV) is the major cause of acute lower \nrespiratory illness in children of less than 5 years of age which...', 'thumbnail': 'https://serpapi.com/searches/67240d5471b0e8fa83649468/images/607ebfc9da9e947c88800119bcb1c3105886b885345262d92cddc68f05b2701a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6357153654098511}","{'position': 2, 'link': 'https://www.canada.ca/en/public-health/services/reports-publications/canada-communicable-disease-report-ccdr/monthly-issue/2020-46/issue-4-april-2-2020/article-1-challenges-developing-vaccine-respiratory-syncytial-virus.html', 'title': 'Overview of the respiratory syncytial virus vaccine candidate pipeline in Canada, CCDR 46(4)', 'source': 'Canada.ca', 'date': 'Apr 2, 2020', 'snippet': 'A vaccine for respiratory syncytial virus (RSV) has been actively sought \nfor over 60 years due to the health impacts of RSV disease in infants.', 'thumbnail': 'https://serpapi.com/searches/67240d5471b0e8fa83649468/images/607ebfc9da9e947c844e9c78b91a65990242e064c8d1ce52e56c548c7bc953c6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.867176353931427}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT01829295,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/two-commonly-used-uveitis-drugs-perform-similarly-nih-funded-clinical-trial', 'title': 'Two commonly used uveitis drugs perform similarly in NIH-funded clinical trial', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Sep 10, 2019', 'snippet': 'Methotrexate and the more expensive mycophenolate mofetil performed \nsimilarly in a head-to-head clinical trial that compared the two drugs for \ntreating...', 'thumbnail': 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Teriflunomide, an oral inhibitor of pyrimidine...', 'thumbnail': 'https://serpapi.com/searches/67240e60d771bdf678dc5744/images/a772ff9c88cff77bf8ce62e09564b4f0487596032eefb7acf90ed9171c23605d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8694962859153748}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/06/27/ms-patients-kesimpta-4-years-saw-no-disease-activity-trials/', 'title': 'MS Patients on Kesimpta for 4 Years Saw No Disease Activity in Trials', 'source': 'Multiple Sclerosis News Today', 'date': 'Jun 28, 2022', 'snippet': 'ALITHIOS trial participants who started on Kesimpta were about four times \nmore likely to have no MS symptoms than those starting on Aubagio.', 'thumbnail': 'https://serpapi.com/searches/67240e60d771bdf678dc5744/images/a772ff9c88cff77bf11ac9193500902b128801ae53d022a575de59081412cdbf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6928902268409729}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/07/06/fewer-ms-relapses-brain-lesions-seen-up-5-years-with-kesimpta/', 'title': 'Fewer MS relapses, brain lesions seen for up to 5 years with Kesimpta', 'source': 'Multiple Sclerosis News Today', 'date': 'Jul 6, 2023', 'snippet': 'In people with relapsing MS, treatment with Kesimpta resulted in reductions \nin relapse rates and brain lesions, and increases in NEDA-3.', 'thumbnail': 'https://serpapi.com/searches/67240e60d771bdf678dc5744/images/a772ff9c88cff77b704afbb1c0eb06a69ebf4f223f9f7e95c73fec2da1aa0e38.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8175560235977173}","{'position': 4, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2020/09/08/novartis-data-at-actrims-ectrims-highlight-the-strength-of-leading-multiple-sclerosis-ms-portfolio-with-life-changing-therapies-for-people-across-the-ms-spectrum/', 'title': '#MSVirtual2020 – Novartis to Present Latest Data on Kesimpta, Mayzent and Gilenya', 'source': 'Multiple Sclerosis News Today', 'date': 'Sep 11, 2020', 'snippet': 'Novartis will present latest study findings on its approved therapies for \nrelapsing MS at the MSVirtual2020 meeting running Sept. 11 to 13..', 'thumbnail': 'https://serpapi.com/searches/67240e60d771bdf678dc5744/images/a772ff9c88cff77bc2aec63cdee2b7ce475d1b310e942198e9a696c00cc9c9de.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.857699453830719}","{'position': 5, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2022/10/25/iv-ofatumumab-reduces-relapses-but-not-better-than-kesimpta/', 'title': 'IV Ofatumumab Reduces Relapses in MS, But Not Better Than Kesimpta', 'source': 'Multiple Sclerosis News Today', 'date': 'Oct 25, 2022', 'snippet': 'An into-the-vein formulation of ofatumumab reduced relapse rates for MS \npatients, but not by as much as the approved under-the-skin...', 'thumbnail': 'https://serpapi.com/searches/67240e60d771bdf678dc5744/images/a772ff9c88cff77b047d91ae9f67ade6d262fd78270fcf80d148331d51ca4ce9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5159135460853577}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT00105443,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0708857', 'title': 'Sorafenib in Advanced Hepatocellular Carcinoma', 'source': 'The New England Journal of Medicine', 'date': 'Apr 28, 2018', 'snippet': 'No effective systemic therapy exists for patients with advanced \nhepatocellular carcinoma. A preliminary study suggested that sorafenib, an \noral multikinase...', 'thumbnail': 'https://serpapi.com/searches/67240e6496a32968339e6251/images/0ce2af43f79dd96563bf06407eb2e19a51e2143ad9106354f164d4d7ff945f69.png', 'sentiment': 'negative', 'sentiment_prob': 0.8031277060508728}",,,,,,,,,,['negative'],negative,0 NCT02721069,"{'position': 1, 'link': 'https://dravetsyndromenews.com/news/fda-approves-valtoco-to-treat-seizure-clusters-in-epilepsy-patients-6-and-older/', 'title': 'FDA Approves Valtoco Nasal Spray to Treat Seizure Clusters in Epilepsy Patients, 6 and Older', 'source': 'Dravet Syndrome News', 'date': 'Jan 28, 2020', 'snippet': 'The United States Food and Drug Administration (FDA) has approved Valtoco \n(diazepam nasal spray) as a rescue treatment for acute, repetitive seizures \n(seizure...', 'thumbnail': 'https://serpapi.com/searches/67240e7e3c9575b4e24ead82/images/3455b0060bee105bd2e6fa9f0366eea0b81c7699b499c4085546d7f1c7d0bcd9.jpeg', 'sentiment': 'neutral', 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in patients with MCL \nreveal encouraging efficacy outcomes with concurrent ibrutinib and \nvenetoclax.', 'thumbnail': 'https://serpapi.com/searches/67240eb92407935cc5390db8/images/5cf54f410be74b6c673fd6adaa2b637e80e8dc134750e74b9411c582377cc032.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6122835278511047}",,,,,,,,,,['neutral'],neutral,1 NCT04102579,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/news/ingrezza-effects-chorea-stronger-over-time-trial-analysis/', 'title': 'Ingrezza’s effects on chorea become stronger over time: Trial analysis', 'source': ""Huntington's Disease News"", 'date': 'Jun 11, 2024', 'snippet': ""Ingrezza's effects on Huntington's-associated chorea appear stronger over \ntime, according to an analysis of the Phase 3 KINECT-HD trial."", 'thumbnail': 'https://serpapi.com/searches/67240ec31397ba2adff57b8e/images/21af894216da2367dbb70e123b5ccaac9dc59ca87fd8124166f67fd6ab3aa2a5.png', 'sentiment': 'neutral', 'sentiment_prob': 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valbenazine for Huntington's-associated chorea."", 'thumbnail': 'https://serpapi.com/searches/67240ec31397ba2adff57b8e/images/21af894216da2367b3f995a9473b1fac37361cc7af46d4e4f0842d29a7c83df4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9441635608673096}","{'position': 7, 'link': 'https://huntingtonsdiseasenews.com/news/kinect-hd2-study-oral-valbenazine-chorea-enrolling/', 'title': ""Huntington's Patients Sought for KINECT-HD2 Study of Oral Valbenazine"", 'source': ""Huntington's Disease News"", 'date': 'Dec 7, 2021', 'snippet': ""The Huntington Study Group seeks 30 patients to join KINECT-HD2, a U.S. and \nCanada study of valbenazine capsules for chorea in Huntington's."", 'thumbnail': 'https://serpapi.com/searches/67240ec31397ba2adff57b8e/images/21af894216da2367ebaca8959a714c584e6adff53da44eba6ea72bf8bbdd8efa.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9417083263397217}",,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 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an interview, Mirum CEO Chris Peetz called patient responses ""dramatic"" \nfor now-approved therapy Livmarli in the broadest-ever PFIC...', 'thumbnail': 'https://serpapi.com/searches/67240ec471b0e8fa836494b8/images/296e858e3c5bbeb042a854304e9c4e6b77b039dbea51b38834e7121137d5cdd5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7903364300727844}","{'position': 3, 'link': 'https://liverdiseasenews.com/news/mirums-livmarli-approved-us-pfic-patients-ages-5-older/', 'title': ""Mirum's Livmarli approved in US for PFIC patients ages 5 and older"", 'source': 'Liver Disease News', 'date': 'Mar 13, 2024', 'snippet': ""The US Food and Drug Administration (FDA) has approved Mirum \nPharmaceuticals' Livmarli (maralixibat) to reduce pruritus, or itching, in \nadults and children, 5..."", 'thumbnail': 'https://serpapi.com/searches/67240ec471b0e8fa836494b8/images/296e858e3c5bbeb04e6533d292dce7500d38621ba8a054e002467c01900bcf59.png', 'sentiment': 'neutral', 'sentiment_prob': 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Genetic variants on one allele...', 'thumbnail': 'https://serpapi.com/searches/67240ee3d169152357052468/images/b26c94d891d16eacc4d112874e68df934ac3e56e86b7189a31be522ce3c0968d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6038366556167603}",,,,,,,,,,['neutral'],neutral,1 NCT04631016,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-36642-y', 'title': 'Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction', 'source': 'Nature', 'date': 'Jun 17, 2023', 'snippet': 'Interleukin (IL)-33 is a broad-acting alarmin cytokine that can drive \ninflammatory responses following tissue damage or infection and is a...', 'thumbnail': 'https://serpapi.com/searches/67240ef83ad34db6ba164f0d/images/e643e8e6a23448d455b25231fe5187d5888c4a8597eee13393149e36a640813a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8236860036849976}",,,,,,,,,,['neutral'],neutral,1 NCT02913482,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2009965', 'title': 'Risdiplam in Type 1 Spinal Muscular Atrophy', 'source': 'The New England Journal of Medicine', 'date': 'Feb 24, 2021', 'snippet': 'In infants with type 1 spinal muscular atrophy, treatment with oral \nrisdiplam led to an increased expression of functional SMN protein in the \nblood.', 'thumbnail': 'https://serpapi.com/searches/67240f260197dd4dd75e85de/images/36bca74b50ae808a3de0be00d64720797cef31492408629f25853315425b1b3e.png', 'sentiment': 'negative', 'sentiment_prob': 0.5097610950469971}","{'position': 2, 'link': 'https://smanewstoday.com/news/british-columbia-funds-evrysdi-canadian-province-sma-patients/', 'title': 'Evrysdi for SMA Patients in British Columbia Being Offered at No Cost', 'source': 'SMA News Today', 'date': 'Feb 21, 2022', 'snippet': 'The provincial government of British Columbia will cover the cost of \nEvrysdi (risdiplam), the oral spinal muscular atrophy (SMA) therapy \napproved by Health...', 'thumbnail': 'https://serpapi.com/searches/67240f260197dd4dd75e85de/images/36bca74b50ae808ac4a0b2a620092558945127b966709c08885d3a1ab927c79f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9134345054626465}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT02435849,"{'position': 1, 'link': 'https://www.nejm.org/doi/abs/10.1056/NEJMoa1709866', 'title': 'Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia', 'source': 'The New England Journal of Medicine', 'date': 'May 2, 2018', 'snippet': 'In a single-center phase 1–2a study, the anti-CD19 chimeric antigen \nreceptor (CAR) T-cell therapy tisagenlecleucel produced high rates of \ncomplete remission...', 'thumbnail': 'https://serpapi.com/searches/67240f44a3657a0b1b93349a/images/376bd3c636d57558885b411cee1292f6a893db10b831279f75fd21e836f3ce6e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8682266473770142}",,,,,,,,,,['neutral'],neutral,1 NCT01253629,"{'position': 1, 'link': 'https://fragilexnewstoday.com/news/decisional-intervention-may-be-beneficial-for-parents-of-fxs-chidren/', 'title': 'Information, Support May Persuade Parents of FXS Children to Join Trials', 'source': 'Fragile X News Today', 'date': 'Feb 19, 2019', 'snippet': 'Parents of children with intellectual disability, in particular those \naffected by fragile X syndrome, may benefit from more information and \ndedicated support.', 'thumbnail': 'https://serpapi.com/searches/67240f43671f3f6cb4ef6937/images/c356a640c4ad8b7a51ea8b83e5d7a580497becbfaf879a8f0ff74febb122b2d7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6160650849342346}",,,,,,,,,,['neutral'],neutral,1 NCT03493854,"{'position': 1, 'link': 'https://www.targetedonc.com/view/pharmacokinetics-of-subcutaneous-her2-therapy-noninferior-in-bc', 'title': 'Pharmacokinetics of Subcutaneous HER2 Therapy Noninferior in BC', 'source': 'Targeted Oncology', 'date': 'Feb 29, 2024', 'snippet': 'Rebecca A. Shatsky, MD, discusses the outcomes of the phase 3 FeDeriCa \nstudy of subcutaneous trastuzumab and pertuzumab in patients with...', 'thumbnail': 'https://serpapi.com/searches/67240f47f933885255e2a916/images/ef0c2bb4f847fbca9a4d6e64087685ea476b2a92948f6ba54c99c746a395711a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9377185702323914}",,,,,,,,,,['neutral'],neutral,1 NCT02578680,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.22.01989', 'title': 'Pembrolizumab Plus Pemetrexed and Platinum in Nonsquamous Non–Small-Cell Lung Cancer: 5-Year Outcomes From the Phase 3 KEYNOTE-189 Study | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Feb 21, 2023', 'snippet': 'Clinical trials frequently include multiple end points that mature at \ndifferent times. The initial report, typically on the based on the...', 'thumbnail': 'https://serpapi.com/searches/67240f49be1497febb69e31c/images/69fa963e7d62a308b9341e1c04f2efa2dd4a35a06de2129658bb6df91b97b5e1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9086083769798279}",,,,,,,,,,['neutral'],neutral,1 NCT00328653,"{'position': 1, 'link': 'https://www.empr.com/home/news/verkazia-approved-for-vernal-keratoconjunctivitis/', 'title': 'Verkazia Approved for Vernal Keratoconjunctivitis', 'source': 'Medical Professionals Reference', 'date': 'Jun 24, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Verkazia™ (cyclosporine \nophthalmic emulsion) 0.1% for the treatment of vernal...', 'thumbnail': 'https://serpapi.com/searches/67240f4cf79a01c1cc6c4326/images/a8e20ae82a3fed7ff67dcf0d0bdaec685da2f9db0c0e4d4c285c37580a183da2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.849105179309845}",,,,,,,,,,['neutral'],neutral,1 NCT03225651,"{'position': 1, 'link': 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(NCT01303172),...', 'thumbnail': 'https://serpapi.com/searches/67240f57b4b72d05f5120035/images/cae5d65a2fc2a1089a139f78cce867d933d438503a2e1fedde5609711fe2ada7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8937485814094543}",,,,,,,,,,['neutral'],neutral,1 NCT02062060,"{'position': 1, 'link': 'https://www.empr.com/home/news/xeglyze-abametapir-head-lice-treatment-approved/', 'title': 'Head Lice Treatment Xeglyze Gets FDA Approval', 'source': 'Medical Professionals Reference', 'date': 'Jul 29, 2020', 'snippet': ""The Food and Drug Administration (FDA) has approved Xeglyze™ (abametapir; \nDr. Reddy's Laboratories) for the treatment of head lice..."", 'thumbnail': 'https://serpapi.com/searches/67240fc998876dfdc6bb4b43/images/4004f09e3131124d1016e4a00e0e6d8bd9d9a3069873c40349e7ac690644849d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7157039046287537}",,,,,,,,,,['neutral'],neutral,1 NCT05438602,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2309002', 'title': 'Oral Nirmatrelvir–Ritonavir as Postexposure Prophylaxis for Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Jul 17, 2024', 'snippet': 'Clinical trials of treatments for coronavirus disease 2019 (Covid-19) have \nnot shown a significant benefit of postexposure prophylaxis.', 'thumbnail': 'https://serpapi.com/searches/67240f9c5c7cb9f0907716d8/images/a79be84c4a5721f7343a5d20ec1996a512f2690515524418742eeef297b699ce.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5386345982551575}","{'position': 2, 'link': 'https://pharmaceutical-journal.com/article/ld/webinar-covid-19-antivirals-where-are-we-now', 'title': 'Webinar: COVID-19 antivirals — where are we now?', 'source': 'The Pharmaceutical Journal', 'date': 'Sep 25, 2023', 'snippet': 'A panel of experts discuss the use of antivirals for the treatment of \nCOVID-19, with consideration for the current landscape and future variants.', 'thumbnail': 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biomarkers assessed by scoring of \nimmunohistochemically (IHC)-stained tissue, which is subjective,...', 'thumbnail': 'https://serpapi.com/searches/67240fab08abe42058644364/images/22b746555f0a1e6c01e90e410efefc7d228a38e0f2431bcaf627c048906760c8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8105503916740417}","{'position': 3, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19%2930097-X/fulltext', 'title': 'Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive breast cancer previously treated with trastuzumab emtansine: a dose-expansion, phase 1 study', 'source': 'The Lancet', 'date': 'Apr 29, 2019', 'snippet': 'Trastuzumab deruxtecan (DS-8201a) is a novel HER2-targeted antibody–drug \nconjugate with a humanised anti-HER2 antibody,...', 'thumbnail': 'https://serpapi.com/searches/67240fab08abe42058644364/images/22b746555f0a1e6caba2414df2e90318d47779b060b5dadebe6832e34207abd9.png', 'sentiment': 'neutral', 'sentiment_prob': 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(Rystiggo®)', 'source': 'UCB', 'date': 'Aug 30, 2024', 'snippet': 'Autoimmune Encephalitis, A Study to Test the Efficacy, Safety, and \nPharmacokinetics of Rozanolixizumab in Adult Study Participants With...', 'thumbnail': 'https://serpapi.com/searches/67240fbaa88278108589f26c/images/469d1f1d65fa4e8d87fb79faab049dbdc34303ce00dbe8510197831edd5d65a0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8345304131507874}","{'position': 2, 'link': 'https://myastheniagravisnews.com/rozanolixizumab-ucb7665/', 'title': 'Rystiggo (rozanolixizumab-noli) for myasthenia gravis', 'source': 'Myasthenia Gravis News', 'date': 'Jan 25, 2024', 'snippet': 'Rystiggo (rozanolixizumab-noli) is an injection therapy approved for adults \nwith generalized myasthenia gravis (gMG) who have antibodies against the...', 'thumbnail': 'https://serpapi.com/searches/67240fbaa88278108589f26c/images/469d1f1d65fa4e8d43b5ea1ec64e995d6a2912853599110d7a48989df462a5a7.png', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'Apr 26, 2024', 'snippet': 'Alteplase, a biosynthetic form of human tissue‐type plasminogen activator, \nis Food and Drug Administration‐approved for the treatment of...', 'thumbnail': 'https://serpapi.com/searches/67241001460b15a5b5a4b7f1/images/a259ae7735156aa4aa585c7000eaccf10e117b9b0a1a68a86051aa976f4f8ad7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9013330936431885}",,,,,,,,,,['neutral'],neutral,1 NCT01384734,"{'position': 1, 'link': 'https://life4me.plus/en/news/fostemsavir-5423/', 'title': 'On CROI were presented the latest data of the effectiveness and safety of fostemsavir', 'source': 'Life4me+', 'date': 'Aug 12, 2019', 'snippet': 'In Seattle were released the latest information about studies of \nfostemsavir - a drug for the treatment of HIV infection of a fundamentally \nnew type.', 'thumbnail': 'https://serpapi.com/searches/672410018db376555d9e59c8/images/3617882acf256bb49073606bfd994e6780fd4fd90ef0c1c45a0b8fae1520c791.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8979955315589905}",,,,,,,,,,['neutral'],neutral,1 NCT02057341,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCGEN.122.003730', 'title': 'Efficacy and Safety of ARRY-371797 in LMNA -Related Dilated Cardiomyopathy: A Phase 2 Study', 'source': 'American Heart Association Journals', 'date': 'Dec 14, 2022', 'snippet': 'Background:Lamin A/C gene (LMNA)-related dilated cardiomyopathy is a \nserious and life-threatening condition with a high unmet medical need.', 'thumbnail': 'https://serpapi.com/searches/672410288b84c422b06ed859/images/5cbb9e4a30e88055f6524e6923f168572b798e5d570ef878a7295a6cced91f91.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7965096831321716}","{'position': 2, 'link': 'https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2020.00761/full', 'title': 'The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype', 'source': 'Frontiers', 'date': 'Jul 3, 2020', 'snippet': '1Humanitas Clinical and Research Center – IRCCS, Rozzano, Italy; 2Institute \nof Genetic and Biomedical Research (IRGB) – UOS of Milan,...', 'thumbnail': 'https://serpapi.com/searches/672410288b84c422b06ed859/images/5cbb9e4a30e88055c128c6fab487ece1d09c32ae0dde5c6010c92dff7d1e416f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9251209497451782}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02974855,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/marstacimab-lowers-bleed-rates-hemophilia-patients-no-inhibitors/', 'title': 'Marstacimab seen to lower bleed rates in hemophilia in Phase 3 trial', 'source': 'Hemophilia News Today', 'date': '٣١\u200f/٠٥\u200f/٢٠٢٣', 'snippet': ""In a Phase 3 clinical trial, Pfizer's marstacimab was found to lower bleed \nrates for both hemophilia A and B patients without inhibitors."", 'thumbnail': 'https://serpapi.com/searches/672410294791c4792972095f/images/e169e39effb17a7a1b03e3fec80b1d798ea8ff88112cbbd7f8ccc647ebdc9136.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6721058487892151}","{'position': 2, 'link': 'https://hemophilianewstoday.com/news/hemophilia-patients-treated-with-marstacimab-see-fewer-bleeds-study/', 'title': 'Hemophilia Patients Treated With Marstacimab See Fewer Bleeds: Study', 'source': 'Hemophilia News Today', 'date': '٢٣\u200f/٠٩\u200f/٢٠٢٢', 'snippet': 'The positive results with the experimental antibody marstacimab held up for \nboth hemophilia A and B patients, even those with an inhibitor.', 'thumbnail': 'https://serpapi.com/searches/672410294791c4792972095f/images/e169e39effb17a7a24de2fde45d0c1a7fac78c377acf0cffa9c1c3ca75a7f291.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6740753054618835}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00102739,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa073275', 'title': 'Eltrombopag for the Treatment of Chronic Idiopathic Thrombocytopenic Purpura', 'source': 'The New England Journal of Medicine', 'date': 'Mar 13, 2017', 'snippet': 'This study was designed to assess whether eltrombopag could safely increase \nplatelet counts in adults with relapsed or refractory chronic ITP.', 'thumbnail': 'https://serpapi.com/searches/67241031a324362e226c5de4/images/27a75636bea1b0b9a7c096bccff6bb1fe538a7e5374d9d8c25221ce38ddaa480.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8934575915336609}","{'position': 2, 'link': 'https://www.hematologyadvisor.com/home/topics/anemia/alvaiz-approved-for-itp-thrombocytopenia-with-hep-c-and-severe-aplastic-anemia/', 'title': 'Alvaiz Approved for ITP, Thrombocytopenia With Hep C, and Severe Aplastic Anemia', 'source': 'Hematology Advisor', 'date': 'Dec 5, 2023', 'snippet': 'The Food and Drug Administration has approved Alvaiz (eltrombopag tablets), \na thrombopoietin receptor agonist.', 'thumbnail': 'https://serpapi.com/searches/67241031a324362e226c5de4/images/27a75636bea1b0b9d8a34d4b9db53e5018a9f29aa275789b00f6aab57a0e1c4c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7984627485275269}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00428948,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1205511', 'title': 'Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease', 'source': 'The New England Journal of Medicine', 'date': 'Nov 3, 2012', 'snippet': 'In this phase 3, multicenter, double-blind, placebo-controlled, 3-year \ntrial, we randomly assigned 1445 patients, 18 to 50 years of age,...', 'thumbnail': 'https://serpapi.com/searches/6724103a9e5bd566565c442b/images/835e7ffae9fbee07334ced9e2385328dc44be7447e957742ee92f5f25e7df701.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8659112453460693}","{'position': 2, 'link': 'https://www.researchgate.net/figure/New-treatment-proposals-for-chronic-kidney-diseases_tbl2_374836838', 'title': 'New treatment proposals for chronic kidney diseases.', 'source': 'ResearchGate', 'date': 'Nov 24, 2023', 'snippet': 'Chronic kidney disease (CKD) is characterized by renal parenchymal damage \nleading to a reduction in the glomerular filtration rate.', 'thumbnail': 'https://serpapi.com/searches/6724103a9e5bd566565c442b/images/835e7ffae9fbee0791301004fd06268b6e2544ca0c3ad9ec827b58b81d1df311.png', 'sentiment': 'negative', 'sentiment_prob': 0.6147511005401611}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT01142726,"{'position': 1, 'link': 'https://www.rheumatologyadvisor.com/news/baseline-mri-inflammation-may-predict-treatment-response-in-rheumatoid-arthritis/', 'title': 'Baseline MRI Inflammation May Predict Treatment Response in Early Rheumatoid Arthritis', 'source': 'Rheumatology Advisor', 'date': 'Oct 23, 2019', 'snippet': 'Patients with early RA and a high level of MRI inflammation at baseline \nwere more likely to achieve clinical remission with abatacept plus MTX \ncompared with...', 'thumbnail': 'https://serpapi.com/searches/6724104ba5e502cdefc57101/images/53510f0803000bfdb81c63eb341514162f85a42a2769e1dd22c9e57c0ee754fb.jpeg', 'sentiment': 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In recent years, chimeric antigen receptor...', 'thumbnail': 'https://serpapi.com/searches/6724104df8b05d9e91665a0d/images/85f520fb17d7727648af155199074b250b0cec2e21d2fb3318463685fc7a76a5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6280092597007751}",,,,,,,,,,['neutral'],neutral,1 NCT02736266,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.18.01148', 'title': 'Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Oct 20, 2018', 'snippet': 'In the PURE-01 study, patients had a predominant urothelial carcinoma \nhistology and clinical (c)T≤3bN0 stage tumor.', 'thumbnail': 'https://serpapi.com/searches/672410583c944b931648f33e/images/406fceefa75d995e85779e83bec91b3ca8cbcd4e7cdce98c4006b5deceaf1e48.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8714836835861206}","{'position': 2, 'link': 'https://www.nature.com/articles/s41467-023-37568-9', 'title': 'Expression-based subtypes define pathologic response to neoadjuvant immune-checkpoint inhibitors in muscle-invasive bladder cancer', 'source': 'Nature', 'date': 'Apr 27, 2023', 'snippet': 'Our study identifies signatures associated with response to CPI that can be \nused to molecularly stratify patients and suggests therapeutic alternatives.', 'thumbnail': 'https://serpapi.com/searches/672410583c944b931648f33e/images/406fceefa75d995e2f4e4081af60b6515463c87097fe4cb95f5e4a9a62d3c216.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8693649172782898}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02320812,"{'position': 1, 'link': 'https://www.nature.com/articles/s41419-020-02955-3', 'title': 'Stem/progenitor cell-based transplantation for retinal degeneration: a review of clinical trials | Cell Death & Disease', 'source': 'Nature', 'date': 'Sep 23, 2020', 'snippet': 'We provide a comprehensive overview on the progression of clinical trials \nfor RD treatment using four types of stem/progenitor cell-based \ntransplantation.', 'thumbnail': 'https://serpapi.com/searches/6724105f39e2327bf63a6edf/images/976cde1b450f8f0a45df4465d6b3cc8d20d5f2ad617111ac3f773a164d4ac431.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9178408980369568}",,,,,,,,,,['neutral'],neutral,1 NCT01546818,"{'position': 1, 'link': 'https://pharmafile.com/news/hiv-vaccine-candidate-successfully-optimised-for-industrial-production/', 'title': 'HIV vaccine candidate successfully optimised for industrial production', 'source': 'Pharmafile', 'date': '1 day ago', 'snippet': 'Natalia Elliot | October 30, 2024 | News story | Research and Development | \nHIV, HIV/AIDS, Naobios, Sumagen, Vaccine, agreement.', 'thumbnail': 'https://serpapi.com/searches/6724106b167793224537b949/images/ad8ad597b60297f5271b5cb15bdac969d998f99c1e4d6a431874de538b4db62a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6182410717010498}",,,,,,,,,,['positive'],positive,1 NCT02933697,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062779', 'title': 'A Randomized Controlled Trial Comparing Apixaban With the Vitamin K Antagonist Phenprocoumon in Patients on Chronic Hemodialysis: The AXADIA-AFNET 8 Study | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 6, 2022', 'snippet': 'Background:Non–vitamin K oral anticoagulants have become the standard \ntherapy for preventing stroke and ischemic thromboembolism in most...', 'thumbnail': 'https://serpapi.com/searches/67241074a9210b5559bfdc13/images/471003ae5327eadb6a421b549d69428547113d48039aa66bb54bdd5095f2655e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9289031028747559}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061647', 'title': 'Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and End-Stage Renal Disease: Lessons Learned', 'source': 'American Heart Association Journals', 'date': 'Dec 5, 2022', 'snippet': 'Observational studies suggest that warfarin is associated with net harm in \npatients with AF on dialysis, 3 but the data are of low quality.', 'thumbnail': 'https://serpapi.com/searches/67241074a9210b5559bfdc13/images/471003ae5327eadbbe846d54e50befd5a1b85a53b0c3034ad9624aba17f626b3.png', 'sentiment': 'negative', 'sentiment_prob': 0.6714184880256653}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT05333289,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-39376-7', 'title': 'Safety and immunogenicity of a phase 1/2 randomized clinical trial of a quadrivalent, mRNA-based seasonal influenza vaccine (mRNA-1010) in healthy adults: interim analysis', 'source': 'Nature', 'date': 'Jun 19, 2023', 'snippet': 'Despite vaccine availability, influenza remains a substantial global public \nhealth concern. Here, we report interim findings on the primary...', 'thumbnail': 'https://serpapi.com/searches/6724107eec54100b6f92697c/images/f9a6f0d53259978b39ebd6c2d6cd9316321bda1c255558ef8e3f19a0ba5a46ec.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8802207112312317}",,,,,,,,,,['neutral'],neutral,1 NCT01743768,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1411776', 'title': 'Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme', 'source': 'The New England Journal of Medicine', 'date': 'May 17, 2015', 'snippet': 'The most prevalent phenotype of asthma is characterized by \neosinophil-dominated inflammation that is driven by a type 2 helper T cell \n(Th2).', 'thumbnail': 'https://serpapi.com/searches/67241082ca6f0c90182439cd/images/fabec85ac2aef8165bb81fe3cec2867e70fb75917e23db6c1135fefc45f6e706.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5749281644821167}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202300374', 'title': 'Therapeutic DNAzymes: From Structure Design to Clinical Applications - Yan - 2023 - Advanced Materials', 'source': 'Wiley Online Library', 'date': 'Feb 4, 2023', 'snippet': 'During the tortuous development period, the research direction of \ntherapeutic deoxyribozymes changes from verification of therapeutic...', 'thumbnail': 'https://serpapi.com/searches/67241082ca6f0c90182439cd/images/fabec85ac2aef81699b524cdc4a616d6cc966ad6daf694a9bbcdb4cb08d8de81.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8990408778190613}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01901432,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-020-0735-y', 'title': 'Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part Phase Ib/II study', 'source': 'Nature', 'date': 'Feb 11, 2020', 'snippet': 'Polycythemia vera (PV) is a chronic myeloproliferative neoplasm (cMPN) \ncharacterized by stem cell-derived clonal myeloproliferation...', 'thumbnail': 'https://serpapi.com/searches/6724109e7b05ca37a09e4a1a/images/23f9c506787b4a53ecf460eabf66a5c093dba3eb59ff71888885329b6861e716.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8484344482421875}",,,,,,,,,,['neutral'],neutral,1 NCT01761266,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2020/11/06/tecentriq-avastin-combo-approved-europe-to-treat-advanced-or-inoperable-liver-cancer/', 'title': 'Tecentriq-Avastin Combo Approved in Europe for Advanced or Inoperable Liver Cancer', 'source': 'Immuno-Oncology News', 'date': 'Nov 6, 2020', 'snippet': 'Tecentriq plus Avastin was found to be superior to standard care as a \nfirst-line treatment of adults with advanced or inoperable...', 'thumbnail': 'https://serpapi.com/searches/672410a25ddfba8fdaa1fcf6/images/c1109c06f82b40996153efc92fe382c33d6ff0a640c2308c375969fa10f77ebf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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placebo-controlled, phase 3 studies', 'source': 'The Lancet', 'date': 'Mar 2, 2023', 'snippet': 'Etrasimod as induction and maintenance therapy for ulcerative colitis \n(ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies', 'thumbnail': 'https://serpapi.com/searches/672410ba2fab6292b8d52dde/images/731fdba1ea8363b56207092852a6434bd7b283d27a0b0ba52cf65d0ebcf565b2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7826459407806396}","{'position': 2, 'link': 'https://www.genengnews.com/topics/drug-discovery/pfizer-to-acquire-arena-for-6-7b-expanding-immuno-inflammatory-pipeline/', 'title': 'Pfizer to Acquire Arena for $6.7B, Expanding Immuno-Inflammatory Pipeline', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Dec 13, 2021', 'snippet': ""Pfizer has agreed to acquire Arena Pharmaceuticals for approximately $6.7 \nbillion, the companies said today, in a deal designed to expand the buyer's \nimmuno-..."", 'thumbnail': 'https://serpapi.com/searches/672410ba2fab6292b8d52dde/images/731fdba1ea8363b5f988b644e8faf2d6654272fedd1ccac97edd8b49c6ee9360.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8256548047065735}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01259050,"{'position': 1, 'link': 'https://www.cbsnews.com/detroit/news/adeona-reports-positive-study-results-for-zinc-treatment-of-als/', 'title': 'Adeona Reports Positive Study Results For Zinc Treatment Of ALS', 'source': 'CBS News', 'date': 'Nov 30, 2011', 'snippet': 'ANN ARBOR -- Adeona Pharmaceuticals (NYSE Amex: AEN) Wednesday said that \nits clinical collaborator for amyotrophic lateral sclerosis (ALS),...', 'thumbnail': 'https://serpapi.com/searches/672410cbf9f904be0f4593a5/images/0a3e83ab9162d21b2688464235df2f2d01b62b5db02f5f6f6bc19dd1018d7a12.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5707696676254272}",,,,,,,,,,['neutral'],neutral,1 NCT04155645,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/abs/10.1161/circ.144.suppl_1.9747', 'title': 'Abstract 9747: Safety, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of AZD8233, Targeting PCSK9, in Patients with Dyslipidemia', 'source': 'American Heart Association Journals', 'date': 'Nov 8, 2021', 'snippet': 'Introduction: Inhibition of proprotein convertase subtilisin/kexin type 9 \n(PCSK9) reduces cardiovascular risk by lowering low-density...', 'thumbnail': 'https://serpapi.com/searches/672410dbe45f33d6d2690d01/images/a890bc4c1a9486bf20884cb9f50a17132f17dee38befb5b27af0a04f11f5f818.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8961273431777954}",,,,,,,,,,['neutral'],neutral,1 NCT02623322,"{'position': 1, 'link': 'https://www.nature.com/articles/d41587-019-00013-8', 'title': 'Drug makers chase anti-flu pill', 'source': 'Nature', 'date': 'May 12, 2019', 'snippet': 'Drug makers are targeting flu virus vulnerabilities to develop antivirals \nthat not only stop infections in their tracks, but also temper emergence of \ndrug...', 'thumbnail': 'https://serpapi.com/searches/672410efb57db8f4c1c62dab/images/b3281d41d9f5af7a42d7b1ac47e86e3703bfb74ebd616246813845c9d2eaba1d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7620350122451782}",,,,,,,,,,['neutral'],neutral,1 NCT03343626,"{'position': 1, 'link': 'https://www.nature.com/articles/s41579-018-0039-7', 'title': 'Zika virus vaccines', 'source': 'Nature', 'date': 'Jun 19, 2018', 'snippet': 'In this Progress article, we discuss recent preclinical studies and lessons \nlearned from first-in-human clinical trials with ZIKV vaccines.', 'thumbnail': 'https://serpapi.com/searches/67241102b28e6b6e596dddef/images/5ba23ed7d8aae9568f623b611acded9f4599d93f1c44b8b40bfb7bb7877b55c3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9234530925750732}",,,,,,,,,,['neutral'],neutral,1 NCT04084951,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-023-00641-x', 'title': 'Microfluidic cell squeeze-based vaccine comes into clinical investigation', 'source': 'Nature', 'date': 'May 4, 2023', 'snippet': 'Cancer immunotherapy has been widely applied to fight various cancers as \none of the most successful anticancer therapeutic approaches in...', 'thumbnail': 'https://serpapi.com/searches/672411238b7ba7dbdcee52ab/images/2da2e67f6701e135ddaeb342c20f1352de8293b2d158cec82ed766933d58daae.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5192486047744751}",,,,,,,,,,['positive'],positive,1 NCT01566695,"{'position': 1, 'link': 'https://ascopubs.org/doi/abs/10.1200/JCO.20.02619', 'title': 'Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes | Journal of Clinical Oncology', 'source': 'ASCO Publications', 'date': 'Mar 25, 2021', 'snippet': 'Treatment options are limited for patients with lower-risk myelodysplastic \nsyndromes (LR-MDS). This phase III, placebo-controlled trial...', 'thumbnail': 'https://serpapi.com/searches/672411250f1a3394018c9e6e/images/8149385868d4827f7df6218fcddc9a8eb4abae2ec2f6fff9c0a7df708e5c4b71.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7065016031265259}",,,,,,,,,,['neutral'],neutral,1 NCT05375838,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1412478/full', 'title': 'Towards broad-spectrum protection: the development and challenges of combined respiratory virus vaccines', 'source': 'Frontiers', 'date': 'Jun 29, 2024', 'snippet': 'This review delves into the major advancements in the field of combined \nvaccine research, underscoring the strategic use of various platforms.', 'thumbnail': 'https://serpapi.com/searches/67241139d1691523570524dc/images/d2e49ac7e8c39252729200517ff34d045ea3f823251c9fbe13af04def6b785d2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5735475420951843}",,,,,,,,,,['positive'],positive,1 NCT03418688,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/all-patients-gain-trial-show-signs-gum-disease-bacteria-porphyromonas-gingivalis/', 'title': 'All Patients in GAIN Trial Show Signs of Gum Disease Bacteria', 'source': ""Alzheimer's News Today"", 'date': 'Aug 30, 2021', 'snippet': ""Every participant in the Phase 2/3 GAIN clinical trial, which is testing \nCortexyme's experimental medication COR388 (atuzaginstat) in people..."", 'thumbnail': 'https://serpapi.com/searches/6724114f1f3d4b758d225a36/images/771df91804708d00714f836549879dc6d7c7a9920c2acae44dc3f11a86234c5a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7752336263656616}",,,,,,,,,,['neutral'],neutral,1 NCT01920711,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1908655', 'title': 'Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction', 'source': 'The New England Journal of Medicine', 'date': 'Sep 1, 2019', 'snippet': 'The angiotensin receptor–neprilysin inhibitor sacubitril–valsartan led to a \nreduced risk of hospitalization for heart failure or death from \ncardiovascular...', 'thumbnail': 'https://serpapi.com/searches/672411692a7727e9d24441c4/images/cb7484a2f2056406c2ced4e3c6e1fdd0bc48b1147e65465bc9d3711c53dbf254.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6263095140457153}",,,,,,,,,,['neutral'],neutral,1 NCT01247324,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1601277', 'title': 'Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 21, 2016', 'snippet': 'In two identical phase 3 trials, we randomly assigned 821 and 835 patients \nwith relapsing multiple sclerosis to receive intravenous...', 'thumbnail': 'https://serpapi.com/searches/6724116bcc487953868276a6/images/672047ae58d60d02bff1208903f859d517174c4e3bdd3fd268e669f9d70dbea2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9104704856872559}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/03/14/ocrevus-blood-levels-confirmed-disability-progression/', 'title': 'Higher blood levels of Ocrevus lower confirmed disability progression risk', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 14, 2023', 'snippet': 'Higher blood levels of Ocrevus associate with a significantly lower risk of \nconfirmed disability progression during treatment,...', 'thumbnail': 'https://serpapi.com/searches/6724116bcc487953868276a6/images/672047ae58d60d0235a2aea612378ab1fc4f077cfceac47d15c1b88299821667.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7976104617118835}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04821479,"{'position': 1, 'link': 'https://alsnewstoday.com/news/mesenchymal-stem-cell-therapy-safe-potential-slow-als-progression-trial/', 'title': 'ALS Stem Cell Therapy Safe, Shows Potential to Slow Progression in Trial', 'source': 'ALS News Today', 'date': 'Dec 3, 2021', 'snippet': 'A small trial found repeat injections of mesenchymal stem cells safe, with \na potential to significantly slow the rate of ALS progression.', 'thumbnail': 'https://serpapi.com/searches/6724117681bab7b8fdf0d45f/images/e1728962f5126d78447c1b6b0d50d77d3b99c3bd3c268258c6152b2543fbf634.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6009451150894165}",,,,,,,,,,['neutral'],neutral,1 NCT00949949,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00324-2', 'title': 'Overview of current targeted therapy in gallbladder cancer', 'source': 'Nature', 'date': 'Oct 7, 2020', 'snippet': 'Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary \ntract tumor. Unfortunately, only a small population of cancer...', 'thumbnail': 'https://serpapi.com/searches/6724117be30abc0f5d3da90b/images/9a37ec817b1bb5567a0ebb656600b50c924b1b4d33adee06157542c0ec64c56e.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7814876437187195}",,,,,,,,,,['negative'],negative,0 NCT02611817,"{'position': 1, 'link': 'https://www.empr.com/home/news/entyvio-for-subcutaneous-use-approved-for-maintenance-in-crohn-disease/', 'title': 'Entyvio for Subcutaneous Use Approved for Maintenance in Crohn Disease', 'source': 'Medical Professionals Reference', 'date': 'Apr 19, 2024', 'snippet': 'The Food and Drug Administration (FDA) has approved the subcutaneous (SC) \nadministration of Entyvio (vedolizumab) for maintenance therapy in adults.', 'thumbnail': 'https://serpapi.com/searches/6724117fce1a752257c17e81/images/a464dd904abec412e20ce3b085a5945f0fd016c3cabcc7ae067190908ef2dd18.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8533787131309509}","{'position': 2, 'link': 'https://ibdnewstoday.com/2020/02/26/new-entyvio-formulation-given-injection-at-home-leads-crohns-remission-after-one-year-phase-3-trial-results-takeda-announces/', 'title': ""New Entyvio Formulation – Given as Injection at Home – Leads to Crohn's Remission After One Year, Takeda Announces"", 'source': 'IBD News Today', 'date': 'Feb 26, 2020', 'snippet': ""Entyvio maintenance therapy – given as a self-injection at home – led to \nCrohn's disease remission after one year in a Phase 3 study,..."", 'thumbnail': 'https://serpapi.com/searches/6724117fce1a752257c17e81/images/a464dd904abec4124735bf513700663d908ed2312c9744c62423592409907907.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9027442932128906}","{'position': 3, 'link': 'https://ibdnewstoday.com/2020/03/04/panel-recommends-european-approval-of-entyvio-at-home-injection/', 'title': ""At-Home Entyvio Injection for Crohn's Recommended for Europe Approval"", 'source': 'IBD News Today', 'date': 'Mar 4, 2020', 'snippet': ""A European Medicines Agency panel recommended approval of an at-home \ninjection of Entyvio, which is used to treat Crohn's and ulcerative..."", 'thumbnail': 'https://serpapi.com/searches/6724117fce1a752257c17e81/images/a464dd904abec412968dc37e9b06a5dd8770affc040a029cde06a71f48a32e8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8984673619270325}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02276222,"{'position': 1, 'link': 'https://copdnewstoday.com/news/analyses-phase-3-trials-sun-101-eflow-safe-effective-copd/', 'title': 'Analyses of Phase 3 Trials Show SUN-101/eFlow Safe, Effective for COPD', 'source': 'COPD News Today', 'date': 'Nov 2, 2017', 'snippet': 'Pooled data from three Phase 3 clinical trials shows that the investigative \nSUN-101/eFlow product is well-tolerated and improves lung...', 'thumbnail': 'https://serpapi.com/searches/672411811397ba2adff57c25/images/a178281535f3e944b9b4a3deb05ba52644819667ff95775c62fff69f085b83ef.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6960063576698303}","{'position': 2, 'link': 'https://www.researchgate.net/figure/Study-Schematic-for-the-GOLDEN-3-and-GOLDEN-4-studies-a_fig1_318552432', 'title': 'Fig. 1. Study Schematic for the GOLDEN 3 and GOLDEN 4 studies. a', 'source': 'ResearchGate', 'date': 'Mar 3, 2020', 'snippet': 'SUN-101 is a combination of glycopyrrolate delivered through an innovative, \nelectronic nebulizer, intended for the treatment of patients with COPD.', 'thumbnail': 'https://serpapi.com/searches/672411811397ba2adff57c25/images/a178281535f3e944ca11de918b00980983f7b62893415803c992b778622a2254.png', 'sentiment': 'neutral', 'sentiment_prob': 0.907075822353363}","{'position': 3, 'link': 'https://copdnewstoday.com/news/new-drug-application-sunovion-copd-therapy-accepted-fda/', 'title': 'New Drug Application for Sunovion’s COPD Therapy Accepted by FDA', 'source': 'COPD News Today', 'date': 'Oct 20, 2016', 'snippet': ""Read about the FDA acceptance of a New Drug Application for Sunovion's COPD \ntreatment SUN-101 delivered with the eFlow nebulizer."", 'thumbnail': 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'https://www.researchgate.net/publication/337858993_Transcriptomic_analysis_of_human_primary_breast_cancer_identifies_fatty_acid_oxidation_as_a_target_for_metformin', 'title': '(PDF) Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin', 'source': 'ResearchGate', 'date': 'Jan 15, 2020', 'snippet': 'PDF | Epidemiological studies suggest that metformin may reduce the \nincidence of cancer in patients with diabetes and multiple late phase \nclinical.', 'thumbnail': 'https://serpapi.com/searches/6724118a96a32968339e6306/images/36bc91641efbbf89424e4786bcc157de2bab94685bf2beb5b5427f2fed711d55.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8698205947875977}",,,,,,,,,,['neutral'],neutral,1 NCT02445248,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1804980', 'title': 'Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma', 'source': 'The New England Journal of Medicine', 'date': 'Dec 1, 2018', 'snippet': 'The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets \nand eliminates CD19-expressing B cells and showed efficacy against B-cell \nlymphomas.', 'thumbnail': 'https://serpapi.com/searches/6724119235853912a0cb0993/images/3a683ae888bf257d2776fd9d8d76a95e04b1156a8e9395dccc344448046c1168.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8563516139984131}","{'position': 2, 'link': 'https://www.uchicagomedicine.org/forefront/immunotherapy-articles/2018/november/car-t-cell-update-phase-2-clinical-trial', 'title': 'CAR T-cell update: therapy improves outcomes for patients with B-cell lymphoma', 'source': 'UChicago Medicine', 'date': 'Nov 30, 2018', 'snippet': 'An international phase-2 trial of a CAR T-cell therapy found that 52 \npercent of patients responded favorably.', 'thumbnail': 'https://serpapi.com/searches/6724119235853912a0cb0993/images/3a683ae888bf257d448c1a11066029b7b705a1eea37074ccddc8a226beb7afea.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.820311427116394}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04003155,"{'position': 1, 'link': 'https://www.empr.com/cch/veozah-for-the-treatment-of-vasomotor-symptoms-due-to-menopause/', 'title': 'Veozah for the Treatment of Vasomotor Symptoms Due to Menopause', 'source': 'Medical Professionals Reference', 'date': 'Jun 1, 2023', 'snippet': 'Veozah (fezolinetant; Astellas Pharma US, Inc) became the first medication \nwithin its class to be approved by the US Food and Drug Administration (FDA)', 'thumbnail': 'https://serpapi.com/searches/6724119469f8ecce36647418/images/78052b22ac7b8c69b4513feb9782dcde0fe1baa0e8d5c306854e519a1053067a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7362357974052429}","{'position': 2, 'link': 'https://www.empr.com/home/news/veozah-approved-for-moderate-to-severe-vasomotor-symptoms-due-to-menopause/', 'title': 'Veozah Approved for Moderate to Severe Vasomotor Symptoms Due to Menopause', 'source': 'Medical Professionals Reference', 'date': 'May 15, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Veozah™ (fezolinetant) \nfor the treatment of moderate to severe vasomotor symptoms due to...', 'thumbnail': 'https://serpapi.com/searches/6724119469f8ecce36647418/images/78052b22ac7b8c69bb9e1dd6890ac9027ae398ffec1c8170925711dc467d319f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7814399600028992}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00880620,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/parkinsons-disease-treatments-motor-symptoms-rytary/', 'title': 'Rytary (carbidopa and levodopa) for Parkinson’s disease', 'source': ""Parkinson's News Today"", 'date': 'May 8, 2023', 'snippet': ""Rytary is an approved extended-release formulation of carbidopa and \nlevodopa that can help ease disease symptoms in people with Parkinson's."", 'thumbnail': 'https://serpapi.com/searches/6724119fb4fe875869b7a359/images/2346314bc968beab908937df3d552c277bb62ebbc1dd546087d93391d11c605e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6894364356994629}",,,,,,,,,,['neutral'],neutral,1 NCT05232461,"{'position': 1, 'link': 'https://www.prnewswire.com/il/news-releases/neurosense-therapeutics-commences-enrollment-and-dosing-in-its-pharmacokinetic-study-of-primec-for-als-301522680.html', 'title': 'NeuroSense Therapeutics Commences Enrollment and Dosing in its Pharmacokinetic Study of PrimeC for ALS', 'source': 'PR Newswire', 'date': 'Apr 11, 2022', 'snippet': 'It has enrolled and dosed the first healthy volunteer in its \npharmacokinetic (PK) study (NCT05232461) of its lead combination drug \ncandidate PrimeC.', 'thumbnail': 'https://serpapi.com/searches/672411a821b01bfe86d64cef/images/05cf84cd7181ad91b2a00a35ca8306f2e18ecbaf1b2c516d509a54f8d089a441.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8010069727897644}",,,,,,,,,,['neutral'],neutral,1 NCT03496662,"{'position': 1, 'link': 'https://www.nature.com/articles/s43018-022-00349-2', 'title': 'Translational advances in pancreatic ductal adenocarcinoma therapy', 'source': 'Nature', 'date': 'Mar 29, 2022', 'snippet': 'Here, we review recent advances in targeted therapy and immunotherapy for \ntreating subtypes of PDAC with diverse molecular alterations.', 'thumbnail': 'https://serpapi.com/searches/672411b8c0028efedf6861d2/images/e5b2a2513fc003ad627576afc8cf2c9bae5f49694a62b64f1f58d71d40c99678.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8488385677337646}",,,,,,,,,,['neutral'],neutral,1 NCT01363401,"{'position': 1, 'link': 'https://alsnewstoday.com/news/corestem-shares-protocol-long-term-neuronata-r-phase-3-als-trial/', 'title': 'Corestem Shares Protocol for Long-term NeuroNata-R Phase 3 ALS Trial', 'source': 'ALS News Today', 'date': 'Jul 7, 2022', 'snippet': 'Corestem is still enrolling participants in its Phase 3 clinical trial of \nNeuroNata-R (lenzumestrocel), a stem cell therapy that is...', 'thumbnail': 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'Phase 2 Trial Dosing Starts for Experimental Dementia Treatment AL001', 'source': ""Alzheimer's News Today"", 'date': 'May 18, 2022', 'snippet': 'Alzamend Neuro has dosed the first patient in the multiple ascending dose \nportion of its Phase 2a clinical trial of AL001, an investigational oral \ntherapy for...', 'thumbnail': 'https://serpapi.com/searches/6724121afc40bf5b24977fb7/images/2cdedad8d2fbe7f01da677195ba62f23c36846e2894f4846844590b7d9fe2319.png', 'sentiment': 'neutral', 'sentiment_prob': 0.909375786781311}","{'position': 3, 'link': 'https://alzheimersnewstoday.com/news/trial-results-expected-june-lithium-formulation-alzheimers/', 'title': 'Phase 2 trial of lithium formulation for Alzheimer’s now complete', 'source': ""Alzheimer's News Today"", 'date': 'Mar 24, 2023', 'snippet': 'Alzamend Neuro has completed the clinical portion of a Phase 2 trial \ntesting AL001, an investigational formulation of lithium that the company \nis developing to...', 'thumbnail': 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QW: weekly; Q2W: every 2 weeks', 'source': 'ResearchGate', 'date': 'Jun 13, 2021', 'snippet': 'This phase 1 study determined the safety, tolerability, \npharmacokinetics-pharmacodynamics, immunogenicity, and efficacy of the \nanti–CSF-1R antibody LY3.', 'thumbnail': 'https://serpapi.com/searches/67241229f3622a70cad26f36/images/67f22c68ceb8d6bc628b0751a17c39deecc9d64ab5eeb05dae64fcd6829450af.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8917114734649658}",,,,,,,,,,['neutral'],neutral,1 NCT03434379,"{'position': 1, 'link': 'https://www.targetedonc.com/view/atezolizumab-bevacizumab-shows-survival-and-qol-benefit-in-hcc', 'title': 'Atezolizumab/Bevacizumab Shows Survival and QOL Benefit in HCC', 'source': 'Targeted Oncology', 'date': 'May 1, 2024', 'snippet': 'Stacey Stein, MD, discusses the background and outcomes of the IMbrave150 \ntrial of atezolizumab plus bevacizumab in patients with advanced...', 'thumbnail': 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study evaluating vibegron in men with OAB symptoms receiving \npharmacological therapy for BPH met its coprimary and all secondary...', 'thumbnail': 'https://serpapi.com/searches/67241326e50bc005c852d9fe/images/3c626a151c4f2ec378d763c37298cbc66cdd54dd01e4bab8a6d47ea39b7a88a1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7995201945304871}",,,,,,,,,,['neutral'],neutral,1 NCT03529877,"{'position': 1, 'link': 'https://epidermolysisbullosanews.com/news/rdeb-wound-closure-promoted-with-skin-derived-stem-cells/', 'title': 'Skin-derived stem cells promoted wound closure in RDEB: Study', 'source': 'Epidermolysis Bullosa News', 'date': 'Apr 21, 2023', 'snippet': 'Skin-derived stem cells enhanced wound closure in people with recessive \ndystrophic epidermolysis bullosa (RDEB), according to clinical trial data.', 'thumbnail': 'https://serpapi.com/searches/6724125488bcde40dd0324e1/images/33c6f0590b6aa8bdacdb541596ad0ffdc7aa3112ca2e5a0e2e99d213ef9be444.png', 'sentiment': 'neutral', 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'The gene therapy nadofaragene firadenovec-vncg (Adstiladrin) continued to \ndemonstrate durable clinical activity in patients with high-risk, \nBCG-unresponsive...', 'thumbnail': 'https://serpapi.com/searches/672412d0ec54100b3215c0f7/images/51b13b6a496f1df27cc89e3362645ee01a8dabb0ed4a40afa76953e7c5654480.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5285101532936096}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.6768', 'title': 'Novel immunotherapeutic options for BCG-unresponsive high-risk non-muscle-invasive bladder cancer', 'source': 'Wiley Online Library', 'date': 'Dec 1, 2023', 'snippet': 'There are limited therapeutic options for BCG-unresponsive patients with \nnon-muscle-invasive bladder cancer. 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'https://www.nature.com/articles/s41423-023-00992-4', 'title': 'The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment', 'source': 'Nature', 'date': 'Mar 16, 2023', 'snippet': 'Atopic dermatitis (AD) is the most common inflammatory skin disease, and it \nis considered a complex and heterogeneous condition.', 'thumbnail': 'https://serpapi.com/searches/672412dc577da5588d9471da/images/0d9c1ea360fd7ca7b71bf5e3071ac83e72f6eb5de93ae52e6099f3a56014e195.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7401643991470337}",,,,,,,,,,['neutral'],neutral,1 NCT03096314,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1911124', 'title': 'Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients', 'source': 'The New England Journal of Medicine', 'date': 'Dec 11, 2019', 'snippet': 'We conducted a randomized, double-blind, placebo-controlled, phase 3 trial \nof early vitamin D 3 supplementation in critically ill, vitamin D–deficient \npatients...', 'thumbnail': 'https://serpapi.com/searches/672412f2bb64ac868baba277/images/a4311811c055a54306305fd2e50b620be08e454465a1d5fff30b67165bba12af.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8818767070770264}",,,,,,,,,,['neutral'],neutral,1 NCT01997333,"{'position': 1, 'link': 'https://www.nature.com/articles/s41523-021-00244-6', 'title': 'Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer (“METRIC”): a randomized multicenter study | npj Breast Cancer', 'source': 'Nature', 'date': 'May 20, 2021', 'snippet': 'The METRIC study (NCT#0199733) explored a novel antibody–drug conjugate, \nglembatumumab vedotin (GV), targeting gpNMB that is overexpressed...', 'thumbnail': 'https://serpapi.com/searches/672412f3059caf91502b42b8/images/3e5e36b47510530b3c8c2cee43fa3a9a7d3b3dacbf46ee08471cfffcc2a9f7ee.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8773122429847717}",,,,,,,,,,['neutral'],neutral,1 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an initial decline in \nestimated glomerular filtration rate (eGFR).', 'thumbnail': 'https://serpapi.com/searches/672412fabcd65222bfec92c5/images/8187f1b32b6a19ef8c069515ed4d4380d7f76846d912d8da5655577b769b7ef7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7206818461418152}","{'position': 2, 'link': 'https://investor.lilly.com/news-releases/news-release-details/boehringer-ingelheim-and-lilly-expand-heart-failure-program', 'title': 'Boehringer Ingelheim and Lilly expand heart failure program for Jardiance® with new exercise capacity trials', 'source': 'Eli Lilly and Company', 'date': 'Apr 6, 2018', 'snippet': 'EMPERIAL clinical trials will evaluate the effect of Jardiance \n(empagliflozin) on exercise ability and heart failure symptoms in people \nwith chronic heart...', 'thumbnail': 'https://serpapi.com/searches/672412fabcd65222bfec92c5/images/8187f1b32b6a19ef7206920225b56592aa8f82808e63dad686b3a185d62f6967.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'Immunization with radiation-attenuated Plasmodium falciparum (Pf) \nsporozoites (SPZ) in PfSPZ Vaccine, has provided better vaccine efficacy...', 'thumbnail': 'https://serpapi.com/searches/6724126768831e1cdffbda7c/images/a806b6fbec30c301978e214592c0e7f8121ae4f9ae24fda6df32af042a1eb75e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6426528692245483}",,,,,,,,,,['neutral'],neutral,1 NCT01850238,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/aadvac1-alzheimers-vaccine-lessens-signs-neurodegeneration-phase-2-adamant-trial/', 'title': 'Vaccine Seen to Lessen Signs of Neurodegeneration in Phase 2 Trial', 'source': ""Alzheimer's News Today"", 'date': 'Jul 22, 2021', 'snippet': ""AADvac1, an investigational vaccine targeting abnormal tau protein, a \nhallmark of Alzheimer's disease, was found to be safe and effectively \nreduced the signs..."", 'thumbnail': 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The mist-delivered treatment widens airway passages to the \nlungs.', 'thumbnail': 'https://serpapi.com/searches/6724126ca505f777dd2047c0/images/898d8a4214f7975014a1621a3460a22cb36e5a90434a7f67d814587a86844b83.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9299271702766418}",,,,,,,,,,['neutral'],neutral,1 NCT02623426,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/intraocular-corticosteroids-best-treating-complications-chronic-inflammatory-eye-condition', 'title': 'Intraocular corticosteroids best for treating complications of chronic inflammatory eye condition', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Jun 13, 2023', 'snippet': 'Repeat treatment with corticosteroid injections improved vision in people \nwith persistent or recurrent uveitis-related macular edema better than two \nother...', 'thumbnail': 'https://serpapi.com/searches/67241278cc4879535044e67b/images/5509c71851d9a2216c01f64a3bc403b88ad62010d6ef360193c0baa697a85ad2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5174453258514404}",,,,,,,,,,['positive'],positive,1 NCT01468207,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1504370', 'title': 'Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa', 'source': 'The New England Journal of Medicine', 'date': 'Aug 4, 2016', 'snippet': 'Treatment with adalimumab (40 mg weekly), as compared with placebo, \nresulted in significantly higher clinical response rates in both trials at \n12 weeks.', 'thumbnail': 'https://serpapi.com/searches/6724127df3cbfa2fbc7c75f0/images/a61f6e82b0bbf06aad020c4af7cec2ebca216cccfab69fac74225b272b43b0e6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8673570156097412}","{'position': 2, 'link': 'https://www.dermatologyadvisor.com/news/adalimumab-reduces-skin-pain-in-hidradenitis-suppurativa/', 'title': 'Adalimumab Reduces Skin Pain in Hidradenitis Suppurativa', 'source': 'Dermatology Advisor', 'date': 'Jun 22, 2018', 'snippet': 'Outcomes were examined in 2 randomized, double-blind, placebo-controlled, \nparallel-group clinical trials: PIONEER I (ClinicalTrials.gov...', 'thumbnail': 'https://serpapi.com/searches/6724127df3cbfa2fbc7c75f0/images/a61f6e82b0bbf06aa7bda045521d76cd553183441993409ab32431ff94ba9e83.png', 'sentiment': 'neutral', 'sentiment_prob': 0.767997682094574}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03841110,"{'position': 1, 'link': 'https://health.ucsd.edu/news/press-releases/2019-04-01-uc-san-diego-health-treats-cancer-patient-with-stem-cell-derived-natural-killer-cells/', 'title': 'UC San Diego Health Treats 1st Cancer Patient with Stem-Cell Derived Natural Killer Cells', 'source': 'UC San Diego Health', 'date': 'Apr 1, 2019', 'snippet': 'Ruff became the first patient in the world to be treated for cancer with a \nhuman-induced pluripotent stem cell (iPSC)-derived cell therapy called \nFT500.', 'thumbnail': 'https://serpapi.com/searches/672412962379380c131b48cf/images/1fae65866d287361e6b369d38536d88eb53b8587cb929813eb4d60e795798a22.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8793442249298096}",,,,,,,,,,['neutral'],neutral,1 NCT02054806,"{'position': 1, 'link': 'https://cervicalcancernews.com/2017/05/26/early-analysis-of-keytruda-in-advanced-cervical-cancer-showing-promise-in-phase-2-trial/', 'title': 'Keytruda Shows Promise in People with Advanced Disease, Early Phase 2 Trial Results Show', 'source': 'Cervical cancer News', 'date': 'May 26, 2017', 'snippet': 'Read about how Keytruda seems to benefit women with advanced cervical \nsquamous cell cancer in a preliminary analysis of clinical trial data.', 'thumbnail': 'https://serpapi.com/searches/672412a569f8ecce3664745d/images/b7e4841c167a1aed147665b3a96d84ba6af350221fae3ae4b6d6110a1d11ea1e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.774665355682373}",,,,,,,,,,['positive'],positive,1 NCT00291642,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Xyzal-levocetirizine', 'title': 'Levocetirizine (Xyzal®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Allergic Rhinitis, Efficacy and Safety of Levocetirizine 8 Weeks Prior and \nAfter the Onset of the Grass Pollen Season in Subjects With SAR...', 'thumbnail': 'https://serpapi.com/searches/672412a7b7d31dd6bebdbc27/images/79fae632296aca5f2674afa69342843811e1d9c91b15ddad3e5a5ca3fc1f0718.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8934985995292664}",,,,,,,,,,['neutral'],neutral,1 NCT02807636,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30230-0/fulltext', 'title': 'Atezolizumab with or without chemotherapy in metastatic urothelial cancer (IMvigor130): a multicentre, randomised, placebo-controlled phase 3 trial', 'source': 'The Lancet', 'date': 'May 16, 2020', 'snippet': 'Atezolizumab can induce sustained responses in metastatic urothelial \ncarcinoma. 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phase IIa trial (COMBAT study, NCT02826486) to evaluate...', 'thumbnail': 'https://serpapi.com/searches/672414465f9778ca2b75c534/images/4b1ac69a8a9af64256613eff23fdab657053392cdbd61baf0ea8d06faea2b713.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5100520849227905}",,,,,,,,,,['neutral'],neutral,1 NCT03056989,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/columns/cystic-fibrosis-epithelium-sodium-channel-spx-101-spyryx/', 'title': 'Cystic Fibrosis and the Epithelium Sodium Channel: Could SPX-101 Fix It?', 'source': 'Cystic Fibrosis News Today', 'date': 'Mar 26, 2018', 'snippet': ""Columnist Reid D'Amico shares background on an investigational CF therapy \ncalled SPX-101, developed by Spyryx Biosciences, which has shown..."", 'thumbnail': 'https://serpapi.com/searches/6724145dcc4879538682775f/images/f4f78f99ebdc7e8137f2fe24da4dee0bf329f843f1bac1c9704b079198a76264.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8881894946098328}",,,,,,,,,,['neutral'],neutral,1 NCT04735432,"{'position': 1, 'link': 'https://www.neurologylive.com/view/understanding-adapt-sc-results-subcutaneous-efgartigimod-tuan-vu', 'title': 'Understanding the ADAPT-SC Results of Subcutaneous Efgartigimod: Tuan Vu, MD', 'source': 'Neurology live', 'date': 'Nov 2, 2023', 'snippet': 'An overview of the open-label findings from ADAPT-SC, a phase 3 study \nassessing subcutaneous efgartigimod in patients with myasthenia gravis.', 'thumbnail': 'https://serpapi.com/searches/6724138d0197dd4da32e64a7/images/5274a4647b124b1a033fb06115968bcaea274cbdfbf63a6a33865415deb65a72.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9305896759033203}","{'position': 2, 'link': 'https://www.empr.com/home/news/sc-injectable-vyvgart-hytrulo-gets-fda-nod-for-generalized-myasthenia-gravis/', 'title': 'SC Injectable Vyvgart Hytrulo Gets FDA Nod for Generalized Myasthenia Gravis', 'source': 'Medical Professionals Reference', 'date': 'Jun 21, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Vyvgart Hytrulo \n(efgartigimod alfa and hyaluronidase-qvfc) for the treatment of generalized \nmyasthenia...', 'thumbnail': 'https://serpapi.com/searches/6724138d0197dd4da32e64a7/images/5274a4647b124b1a954c3a2f47f31ba08688510d0694469fc744e801f4f6ef27.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8111444115638733}","{'position': 3, 'link': 'https://myastheniagravisnews.com/news/mda-2024-vyvgart-hytrulo-eases-generalized-myasthenia-gravis-symptoms/', 'title': 'MDA 2024: Vyvgart Hytrulo eases disease severity, boosts life quality', 'source': 'Myasthenia Gravis News', 'date': 'Mar 7, 2024', 'snippet': ""Across a Phase 3 extension study's multiple treatment cycles, Vyvgart \nHytrulo reduced myasthenia gravis severity and improved quality of..."", 'thumbnail': 'https://serpapi.com/searches/6724138d0197dd4da32e64a7/images/5274a4647b124b1ae09962fc572824f25de4ef32a3cd49a605ee0e05b7d12abf.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6409837603569031}","{'position': 4, 'link': 'https://myastheniagravisnews.com/news/fda-approves-subcutaneous-efgartigimod-vyvgart-hytrulo-gmg/', 'title': 'FDA approves under-the-skin Vyvgart Hytrulo as treatment for gMG |...', 'source': 'Myasthenia Gravis News', 'date': 'Jun 21, 2023', 'snippet': 'Note: This story was updated June 28, 2023, to correct the time frame of \nthe ADAPT-SC+ clinical trial, in which patients will be treated for...', 'thumbnail': 'https://serpapi.com/searches/6724138d0197dd4da32e64a7/images/5274a4647b124b1ae210bbe630dd6532231a077669b0d563126d2f5b93c8cc37.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9257835149765015}","{'position': 5, 'link': 'https://myastheniagravisnews.com/news/under-skin-vyvgart-injection-approved-europe-achr-positive-gmg/', 'title': 'Under-the-skin Vyvgart approved in Europe for AChR-positive gMG', 'source': 'Myasthenia Gravis News', 'date': 'Nov 17, 2023', 'snippet': 'A new under-the-skin injectable formulation of Vyvgart (efgartigimod alfa) \nhas been approved by the European Commission for adults with generalized \nmyasthenia...', 'thumbnail': 'https://serpapi.com/searches/6724138d0197dd4da32e64a7/images/5274a4647b124b1a37fb4aba6c71c1f533cb5bd27064614131dc730c0c6f11d4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7352441549301147}",,,,,,"['neutral', 'neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT02684006,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1816047', 'title': 'Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma', 'source': 'The New England Journal of Medicine', 'date': 'Feb 16, 2019', 'snippet': 'In a single-group, phase 1b trial, avelumab plus axitinib resulted in \nobjective responses in patients with advanced renal-cell carcinoma.', 'thumbnail': 'https://serpapi.com/searches/672413b2f8b05d9e91665aeb/images/64530f482d7df12249ebbbb57804cc3c4df4b129200656c32906f3619a17e273.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8833085298538208}",,,,,,,,,,['neutral'],neutral,1 NCT00351468,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/home/topics/anemia/alvaiz-approved-for-itp-thrombocytopenia-with-hep-c-and-severe-aplastic-anemia/', 'title': 'Alvaiz Approved for ITP, Thrombocytopenia With Hep C, and Severe Aplastic Anemia', 'source': 'Hematology Advisor', 'date': 'Dec 5, 2023', 'snippet': 'The Food and Drug Administration has approved Alvaiz (eltrombopag tablets), \na thrombopoietin receptor agonist.', 'thumbnail': 'https://serpapi.com/searches/672413e817b10eb84e16bed3/images/798e35d097c59fea87b4157ee1b283e0eaf72171a8e918ef66e89ad6174ba462.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7984627485275269}",,,,,,,,,,['neutral'],neutral,1 NCT05333406,"{'position': 1, 'link': 'https://charcot-marie-toothnews.com/news/stem-cell-therapy-en001-eases-cmt1a-symptoms-small-trial/', 'title': 'Stem cell therapy safely eases CMT1A symptoms in small trial', 'source': 'Charcot-Marie-Tooth News', 'date': 'Jul 3, 2024', 'snippet': 'EN001, a stem cell therapy being developed by Encell, safely eased symptoms \nof CMT1A in a Phase 1 clinical trial involving nine patients.', 'thumbnail': 'https://serpapi.com/searches/672413eea86921b78b34a999/images/6c7afc2c210d42906a9f25e72362c414330414a0560496c29af6905a373f43b5.png', 'sentiment': 'positive', 'sentiment_prob': 0.579399049282074}",,,,,,,,,,['positive'],positive,1 NCT02586025,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45591-7', 'title': 'Neoadjuvant–adjuvant pertuzumab in HER2-positive early breast cancer: final analysis of the randomized phase III PEONY trial', 'source': 'Nature', 'date': 'Mar 9, 2024', 'snippet': 'The randomized, multicenter, double-blind, placebo-controlled, phase III \nPEONY trial (NCT02586025) demonstrated significantly improved total...', 'thumbnail': 'https://serpapi.com/searches/67241409d1119590a4975da7/images/4864fe00ebd34965ac6d2b953a511bf7f3332fa53f228ec23ff07cbf5dcf6695.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Evaluate Safety of Tezepelumab for Atopic Dermatitis', 'source': 'Dermatology Advisor', 'date': 'Mar 22, 2019', 'snippet': 'Two phase 1 studies assessed the safety, tolerability, and pharmacokinetics \nof tezepelumab with evidence of efficacy in asthma and potential...', 'thumbnail': 'https://serpapi.com/searches/672416830d379f62864f8520/images/2ac871a9902d85d66526072cc19e0681982a039334b123145d526cbf812fb144.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8194459676742554}",,,,,,,,,,['neutral'],neutral,1 NCT02312245,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-87470-x', 'title': 'Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting', 'source': 'Nature', 'date': 'Apr 13, 2021', 'snippet': 'Repeated measures studies are frequently performed in patient-derived \nxenograft (PDX) models to evaluate drug activity or compare...', 'thumbnail': 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'https://pulmonaryfibrosisnews.com/news/clinical-studies-ipf-treatment-candidate-advancing-china-us/', 'title': 'Clinical studies of oral IPF treatment INS018_055 advancing in US, China', 'source': 'Pulmonary Fibrosis News', 'date': 'Jul 12, 2024', 'snippet': 'A Phase 2a clinical trial testing the safety of treatment candidate \nINS018_055 among idiopathic pulmonary fibrosis (IPF) patients in the US is \nstill seeking...', 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84a005f793594c8a53aedd6c2fa63a52eeedf70b064dae0a4f6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9229093194007874}","{'position': 2, 'link': 'https://www.eurekalert.org/news-releases/1058384', 'title': 'Insilico Medicine reports positive Phase IIa results for ISM001-055, a novel first-in-class drug treatment for idiopathic pulmonary fibrosis (IPF) designed using generative AI', 'source': 'EurekAlert!', 'date': '1 month ago', 'snippet': 'Insilico Medicine reports positive Phase IIa results for ISM001-055, a \nnovel first-in-class drug treatment for idiopathic pulmonary fibrosis (IPF) \ndesigned...', 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84a3a2516c758af9c97bf8616a9962843eefc2d35fc5637a20f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6900705099105835}","{'position': 3, 'link': 'https://www.nature.com/articles/s41587-024-02143-0', 'title': 'A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models', 'source': 'Nature', 'date': 'Mar 8, 2024', 'snippet': 'Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung \ndisease with a high mortality rate. Putative drug targets in IPF have...', 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84a3db8fc0042b7fcd637c95c2f7d863686c28fc34743910451.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5609192252159119}","{'position': 4, 'link': 'https://pharmatimes.com/news/insilico-medicine-reports-positive-results-for-idiopathic-pulmonary-fibrosis-therapy/', 'title': 'Insilico Medicine reports positive results for idiopathic pulmonary fibrosis therapy', 'source': 'PharmaTimes', 'date': '1 month ago', 'snippet': 'Insilico Medicine, a clinical-stage generative AI-driven drug discovery \ncompany, has announced positive preliminary results from its Phase 2a \nclinical trial of...', 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84aea316f02e392eb62f1da51183d98deee89f273a9c6ebe00a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6266455054283142}","{'position': 5, 'link': 'https://www.eurekalert.org/news-releases/1048870', 'title': 'Insilico Medicine completes patient enrollment in its Phase IIa Study in China investigating INS018_055 for Idiopathic Pulmonary Fibrosis (IPF)', 'source': 'EurekAlert!', 'date': 'Jun 20, 2024', 'snippet': 'The randomized, double-blind, placebo-controlled study is being conducted \nacross 29 clinical centers in China and has completed enrollment...', 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84a3f2389aa742ba09d4dc2b467e64ac92223a5433662fb9813.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8771718144416809}","{'position': 6, 'link': 'https://www.unite.ai/ai-driven-drug-discovery-achieves-milestone-with-insilico-medicines-phase-iia-success-in-treating-pulmonary-fibrosis/', 'title': 'AI-Driven Drug Discovery Achieves Milestone with Insilico Medicine’s Phase IIa Success in Treating Pulmonary Fibrosis', 'source': 'Unite.AI', 'date': '1 month ago', 'snippet': ""Insilico Medicine's Generative AI-designed Drug ISM001-055 Shows Promising \nResults in Phase IIa Clinical Trials."", 'thumbnail': 'https://serpapi.com/searches/672416d221e77bd9839ca8dd/images/2098aad2b1b0b84ae4bb3b07ade871bd359838f244d84132ebad12e9ad9dd6ac.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8786435127258301}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'positive']",neutral,1 NCT00760149,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00191-X/fulltext', 'title': 'Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials', 'source': 'The Lancet', 'date': 'Oct 10, 2023', 'snippet': 'Respiratory tract microbiota has been described as the gatekeeper for \nrespiratory health. We aimed to assess the impact of standard-of-care...', 'thumbnail': 'https://serpapi.com/searches/672416d42c83d5b853e6b908/images/d067471a2841385e022e37dfe16c3af29d761d1d445089eb9a778f3e7c0e1ed5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9092090129852295}",,,,,,,,,,['neutral'],neutral,1 NCT03180437,"{'position': 1, 'link': 'https://www.nature.com/articles/s41423-020-0515-7', 'title': 'Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer', 'source': 'Nature', 'date': 'Sep 16, 2020', 'snippet': 'Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. \nDue to their HLA-independent mode of action, allogeneic Vγ9Vδ2 T...', 'thumbnail': 'https://serpapi.com/searches/672416d611db4595229e7504/images/737737db5e084f45c17f34710914b206b2c7309e14c0d05adb1f4bceef2d2acd.png', 'sentiment': 'positive', 'sentiment_prob': 0.7890372276306152}","{'position': 2, 'link': 'https://www.nature.com/articles/s41392-020-00260-1', 'title': 'Irreversible electroporation plus allogenic Vγ9Vδ2 T cells enhances antitumor effect for locally advanced pancreatic cancer patients', 'source': 'Nature', 'date': 'Oct 23, 2020', 'snippet': 'Immunotherapy has limited efficacy against locally advanced pancreatic \ncancer (LAPC) due to the presence of an immunosuppressive...', 'thumbnail': 'https://serpapi.com/searches/672416d611db4595229e7504/images/737737db5e084f45e24b523dbd6f0aa5cc34caf5410e20e7b96cc78b495e4e17.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4920717477798462}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02546440,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1264842/full', 'title': 'Novel potential pharmacological applications of dimethyl fumarate—an overview and update', 'source': 'Frontiers', 'date': 'Feb 7, 2024', 'snippet': 'Dimethyl fumarate (DMF) is an FDA-approved drug for the treatment of \npsoriasis and multiple sclerosis. DMF is known to stabilize the \ntranscription factor...', 'thumbnail': 'https://serpapi.com/searches/67241474cc4879535044e6fb/images/3f00ba4b7993a5c58a1d2ac1b4034c76dbc01dd8079fdb4a948f4c6272637dd7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6468765139579773}",,,,,,,,,,['neutral'],neutral,1 NCT00985725,"{'position': 1, 'link': 'https://www.nature.com/articles/npp2013334', 'title': 'Lisdexamfetamine Dimesylate Augmentation in Adults With Persistent Executive Dysfunction After Partial or Full Remission of Major Depressive Disorder', 'source': 'Nature', 'date': 'Dec 6, 2013', 'snippet': 'In this trial, LDX augmentation significantly improved executive \ndysfunction and depressive symptoms in participants with mild MDD.', 'thumbnail': 'https://serpapi.com/searches/6724154c460b15a5b5a4b933/images/c4ea4eb8b42ffaa7eff2ec0665ab609eb4c5fa4036618cb851ac3e811401e7e8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7135171294212341}",,,,,,,,,,['neutral'],neutral,1 NCT01487863,"{'position': 1, 'link': 'http://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/61648-asco-2013-poster-a-randomized-phase-ii-trial-of-sipuleucel-t-with-concurrent-or-sequential-abiraterone-acetate-plus-prednisone-in-metastatic-castrate-resistant-prostate-cancer-mcrpc.html', 'title': 'ASCO 2013 - Poster: A randomized, phase II trial of sipuleucel-T with concurrent or sequential abiraterone acetate plus prednisone in metastatic castrate-resistant prostate cancer (mCRPC)', 'source': 'UroToday', 'date': 'Jun 10, 2013', 'snippet': 'CHICAGO, IL USA (UroToday.com) - Presented by Small EJ,1 Lance RS,2 Redfern \nCH,3 Millard FE,4 Gardner TA,5 Karsh LI,6 Dawson N,7 McCoy C,8...', 'thumbnail': 'https://serpapi.com/searches/6724154f8cf8aebae1372273/images/16598361c6c8b27a21bbd675ee1c92ddb6a2cad99e5ea1484a45a6bedc721f39.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9061769843101501}",,,,,,,,,,['neutral'],neutral,1 NCT02851407,"{'position': 1, 'link': 'https://www.nature.com/articles/s41409-023-02007-2', 'title': 'Prevention of veno-occlusive disease/sinusoidal obstruction syndrome: a never-ending story and no easy answer', 'source': 'Nature', 'date': 'May 25, 2023', 'snippet': 'The Harmony Trial (NCT02851407), a prospective randomized trial conducted \namong adults and children, reported that defibrotide was not...', 'thumbnail': 'https://serpapi.com/searches/67241550f79a01c1cc6c448e/images/4b4b3af7d984f889877c83cccbeebdb7142c6da49aa4a530b2964b04c5c43825.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5698968768119812}","{'position': 2, 'link': 'https://www.nature.com/articles/s41409-019-0474-8', 'title': 'Systematic review of defibrotide studies in the treatment of veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS)', 'source': 'Nature', 'date': 'Feb 25, 2019', 'snippet': 'Veno-occlusive disease (VOD), also called sinusoidal obstruction syndrome \n(SOS), is a potentially life-threatening complication of...', 'thumbnail': 'https://serpapi.com/searches/67241550f79a01c1cc6c448e/images/4b4b3af7d984f8898f2ab47935c741affa91c582d2aaa49dd734ff8dbbf184fa.png', 'sentiment': 'negative', 'sentiment_prob': 0.5912196636199951}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT01596335,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-017-18387-7', 'title': 'Infliximab versus intravenous immunoglobulin for refractory Kawasaki disease: a phase 3, randomized, open-label, active-controlled, parallel-group, multicenter trial', 'source': 'Nature', 'date': 'Jan 31, 2018', 'snippet': 'We compared the efficacy and safety of infliximab with intravenous \nimmunoglobulin (IVIG), a standard therapy, in a phase 3 trial...', 'thumbnail': 'https://serpapi.com/searches/6724155069012193a5fed36d/images/711599a13e9821aaafd8df2123e1cd2da69f4f6a5237438045cb1c0cda036d6a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8821622729301453}",,,,,,,,,,['neutral'],neutral,1 NCT01119833,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/phase-3-trial-recruiting-to-test-rivipansel-for-vaso-occlusive-crisis-in-sickle-cell-disease/', 'title': 'Clinical Trial Seeking Vaso-Occlusive Sickle Cell Patients to Test Rivipansel', 'source': 'Sickle Cell Disease News', 'date': 'May 11, 2017', 'snippet': 'A Phase 3 clinical trial to test the effectiveness and safety of the drug \ncandidate rivipansel (GMI-1070) for the treatment of vaso-occlusive crisis \n(VOC) in...', 'thumbnail': 'https://serpapi.com/searches/6724155e642c3189bcbd539a/images/99ac5a983febbbecab4ae38249c75821f9b4d938e9574a2a78bc6330a5b6b5ae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8787412643432617}",,,,,,,,,,['neutral'],neutral,1 NCT04094142,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-47198-4', 'title': 'Combination of acalabrutinib with lenalidomide and rituximab in relapsed/refractory aggressive B-cell non-Hodgkin lymphoma: a single-arm phase II trial', 'source': 'Nature', 'date': 'Mar 30, 2024', 'snippet': 'The authors report a single-arm phase II clinical trial of combination of \nacalabrutinib, lenalidomide and rituximab (R2A) in patients with aggressive \nrelapsed/...', 'thumbnail': 'https://serpapi.com/searches/6724155ed9c3e6887205ef06/images/6107c3b1253085177757ce6bf78c5c8ef69bc5f40b0b36ab70f3d2a0d8f510a4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.903610348701477}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/hon.3164_326', 'title': 'Combination of acalabrutinib with rituximab and lenalidomide in relapsed/refractory B cell non-Hodgkin lymphoma', 'source': 'Wiley Online Library', 'date': 'Jun 9, 2023', 'snippet': 'Previous studies have shown that combination of acalabrutinib with \nrituximab and lenalidomide has a synergistic effect in killing NHL cells.', 'thumbnail': 'https://serpapi.com/searches/6724155ed9c3e6887205ef06/images/6107c3b125308517e5329a1fc4deb06ec9c1e1e2e1d1d445c9480b371e426357.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6753286123275757}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00420212,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/tecfidera-generics-availability-europe/', 'title': 'Generics of Tecfidera not available in Europe until at least 2025', 'source': 'Multiple Sclerosis News Today', 'date': 'Dec 22, 2023', 'snippet': 'The European Commission withdraws its marketing authorizations for generic \nversions of Tecfidera (dimethyl fumarate), a RRMS oral therapy.', 'thumbnail': 'https://serpapi.com/searches/6724157cefad2183fae89b8a/images/4c4bb47576d6b81729729bbd37fa70e41c1b9db96bbf33a9f60e99bb70f6b498.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5986100435256958}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/tecfidera-dimethyl-fumarate-multiple-sclerosis/', 'title': 'Tecfidera (dimethyl fumarate) for MS | Uses, side effects, and more', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 22, 2022', 'snippet': 'Tecfidera (dimethyl fumarate) is an oral treatment for relapsing forms of \nMS. Learn more about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/6724157cefad2183fae89b8a/images/4c4bb47576d6b81757343b4cae65af78db5c68b0f61cb5ae245b0813b09abf6b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8988696932792664}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00274352,"{'position': 1, 'link': 'https://sarcoidosisnews.com/news/adalimumab-humira-can-improve-verrucous-sarcoidosis-case-report/', 'title': 'Benefits of Adalimumab (Humira) in Verrucous Sarcoidosis Cited in Case Report', 'source': 'Sarcoidosis News', 'date': 'Nov 6, 2018', 'snippet': 'Adalimumab can help treat verrucous sarcoidosis — a rare type of skin \nsarcoidosis — associated with human papillomavirus (HPV), according to...', 'thumbnail': 'https://serpapi.com/searches/6724159c20e6ebd6b690e170/images/09f5ae249a0a2fcab2087b60d0bdb58ea37c241f0d0e8e5cc3fcddf52d64911d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6959171891212463}",,,,,,,,,,['neutral'],neutral,1 NCT04737187,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2214963', 'title': 'Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer', 'source': 'The New England Journal of Medicine', 'date': 'May 3, 2023', 'snippet': 'In a previous phase 3 trial, treatment with trifluridine–tipiracil \n(FTD–TPI) prolonged overall survival among patients with metastatic...', 'thumbnail': 'https://serpapi.com/searches/672414c97e1d1fae374b59b8/images/fe16294867b8f512571121e492b496313e0cf6ac234111a102dc2f643499b1f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8692559599876404}","{'position': 2, 'link': 'https://dailynews.ascopubs.org/do/trifluridine-tipiracil-plus-bevacizumab-provides-benefit-refractory-metastatic', 'title': 'Trifluridine/Tipiracil Plus Bevacizumab Provides Benefit in Refractory Metastatic Colorectal Cancer', 'source': 'ASCO Daily News', 'date': 'Jan 21, 2023', 'snippet': 'In the global phase 3 SUNLIGHT study, adding bevacizumab to \ntrifluridine/tipiracil in the treatment of refractory metastatic \ncolorectal...', 'thumbnail': 'https://serpapi.com/searches/672414c97e1d1fae374b59b8/images/fe16294867b8f5122fdec964b30d634aa2164d0028145762c936a69b321b86d3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.785142183303833}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/trifluridine-tipiracil-receives-fda-approval-in-metastatic-crc', 'title': 'Trifluridine/Tipiracil Receives FDA Approval in Metastatic CRC', 'source': 'Cancer Network', 'date': 'Aug 2, 2023', 'snippet': 'Results from the phase 3 SUNLIGHT trial support the approval of \ntrifluridine/tipiracil plus bevacizumab in patients with previously \ntreated,...', 'thumbnail': 'https://serpapi.com/searches/672414c97e1d1fae374b59b8/images/fe16294867b8f512793248ff8cc9482f4f88690c9b35e9a72f23abb5ab15aa79.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7108086347579956}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02682693,"{'position': 1, 'link': 'https://www.onclive.com/view/addition-of-denosumab-to-neoadjuvant-chemo-does-not-lead-to-significant-idfs-differences-in-early-breast-cancer', 'title': 'Addition of Denosumab to Neoadjuvant Chemo Does Not Lead to Significant iDFS Differences in Early Breast Cancer', 'source': 'OncLive', 'date': 'May 17, 2024', 'snippet': 'Adding denosumab to neoadjuvant nab-paclitaxel did not improve 5-year \ninvasive disease-free survival rates in patients with early-stage...', 'thumbnail': 'https://serpapi.com/searches/672414fad0d7e31d070b74b9/images/6e95e5c45472d09580a2dcf36b320055a53285015f06e78b747113f7d32b5769.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.621461808681488}",,,,,,,,,,['negative'],negative,0 NCT03228836,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-021-00768-0', 'title': 'Sintilimab for relapsed/refractory extranodal NK/T cell lymphoma: a multicenter, single-arm, phase 2 trial (ORIENT-4)', 'source': 'Nature', 'date': 'Oct 27, 2021', 'snippet': 'This study (ORIENT-4) aimed to assess the efficacy and safety of \nsintilimab, a humanized anti-PD-1 antibody, in patients with...', 'thumbnail': 'https://serpapi.com/searches/672415165416d82ea72807f5/images/4ac2701d25a52895ada5e5358bf03a8d386aff8ae6537d353b4e61207711a0d8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.880325436592102}",,,,,,,,,,['neutral'],neutral,1 NCT04908462,"{'position': 1, 'link': 'https://fabrydiseasenews.com/news/first-clinical-site-china-opens-phase-2-trial-al01211/', 'title': 'First clinical site in China opens for Phase 2 trial of AL01211 –...', 'source': 'Fabry Disease News', 'date': 'Aug 18, 2023', 'snippet': 'AceLink Therapeutics opened its first clinical site in China for a Phase 2 \nclinical trial testing AL01211 as a treatment for Fabry disease.', 'thumbnail': 'https://serpapi.com/searches/672415e090b57c018e6f3d1b/images/906abbdfba61e2d15f72c0a9c3162e41d41487cb393f305857ea137a5ff4d71d.png', 'sentiment': 'neutral', 'sentiment_prob': 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Advances in Pharmaceutics', 'source': 'Wiley Online Library', 'date': 'Jan 28, 2015', 'snippet': 'Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common \ndisorder of the tear film caused by decreased tear production or...', 'thumbnail': 'https://serpapi.com/searches/67241606361fd42d611f4ad4/images/6017bf8f05cf4d151da37fcf1021c39532585903e9d3f9e20c0ca156da2f5452.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8953704237937927}",,,,,,,,,,['neutral'],neutral,1 NCT05061693,"{'position': 1, 'link': 'https://www.dermatologytimes.com/view/late-breaking-data-povorcitinib-significantly-improves-itch-and-lesions-in-prurigo-nodularis', 'title': 'Late-Breaking Data: Povorcitinib Significantly Improves Itch and Lesions in Prurigo Nodularis', 'source': 'Dermatology Times', 'date': 'Mar 12, 2024', 'snippet': 'Shawn Kwatra, MD, shares positive updates on phase 2 oral povorcitinib for \nprurigo nodularis at AAD 2024.', 'thumbnail': 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'Highlights from SABCS Annual Symposium 2019: HER2-Positive Breast Cancer Updates', 'source': 'Breast Cancer Research Foundation', 'date': '١٥\u200f/٠١\u200f/٢٠٢٠', 'snippet': 'Reports from clinical trials in HER2-positive breast cancer highlight \npromising new agents for patients with advanced disease.', 'thumbnail': 'https://serpapi.com/searches/6724162dbe324f9cf1acab43/images/e1f84ce66f2c48341597245a4cc0bd6ea60ea6fce1dd62f8de7b9f3bc5354047.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5301448702812195}","{'position': 3, 'link': 'https://breastcancer-news.com/2021/01/25/enhertu-conditionally-approved-in-european-union-eu-for-inoperable-advanced-her2-positive-breast-cancer/', 'title': 'Enhertu Approved in EU for Inoperable, Advanced Breast Cancer', 'source': 'Breast Cancer News', 'date': '٢٥\u200f/٠١\u200f/٢٠٢١', 'snippet': 'The European Commission has conditionally approved Enhertu (trastuzumab \nderuxtecan) for adults in the EU with inoperable or metastatic \nHER2-positive breast...', 'thumbnail': 'https://serpapi.com/searches/6724162dbe324f9cf1acab43/images/e1f84ce66f2c48348876f0a488cd4770851e6b6e0a4c7d6ffbf0efff58a2347a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7442876100540161}","{'position': 4, 'link': 'https://breastcancer-news.com/2020/04/30/enhertu-approved-in-japan-to-treat-her2-positive-inoperable-or-metastatic-breast-cancer/', 'title': 'Enhertu Approved for HER2-Positive Inoperable or Metastatic Cancer in Japan', 'source': 'Breast Cancer News', 'date': '٣٠\u200f/٠٤\u200f/٢٠٢٠', 'snippet': ""Enhertu, an antibody-drug conjugate, was approved in Japan to treat adults \nwith inoperable or metastatic breast cancer that's resistant to..."", 'thumbnail': 'https://serpapi.com/searches/6724162dbe324f9cf1acab43/images/e1f84ce66f2c483473a39ed3eeedd31d50dc6df4cac1cc63a7d6c02a950f3248.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.808199942111969}",,,,,,,"['neutral', 'positive', 'neutral', 'neutral']",neutral,1 NCT00729664,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1200694', 'title': 'Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 2, 2012', 'snippet': 'Antibody-mediated blockade of PD-L1 induced durable tumor regression \n(objective response rate of 6 to 17%) and prolonged stabilization of \ndisease.', 'thumbnail': 'https://serpapi.com/searches/67241641b7d31dd6bebdbd10/images/3e4825d465decd1b34913677087b024038ecf5f026083ce583e29bb413c8fdf9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8075860738754272}",,,,,,,,,,['neutral'],neutral,1 NCT02442765,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/avp-786-fails-ease-alzheimers-related-agitation-phase-3-trial/', 'title': 'AVP-786 fails to ease Alzheimer’s-related agitation in Phase 3 trial', 'source': ""Alzheimer's News Today"", 'date': 'Feb 29, 2024', 'snippet': ""A Phase 3 clinical trial of AVP-786 failed to meet its main goal of easing \nagitation in adults with dementia due to Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/672416455a461a841bce4a49/images/91822a38a61756316a0c6a225a052a0aa6a7ed938d8ca25a6f9d6a3528aadde5.png', 'sentiment': 'negative', 'sentiment_prob': 0.8483138084411621}",,,,,,,,,,['negative'],negative,0 NCT03611946,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-live-attenuated-zika-vaccine', 'title': 'NIH begins clinical trial of live, attenuated Zika vaccine', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Aug 16, 2018', 'snippet': 'Vaccinations have begun in a first-in-human trial of an experimental live, \nattenuated Zika virus vaccine developed by scientists at the...', 'thumbnail': 'https://serpapi.com/searches/67241657bb55ff6f6c7448a0/images/0250c23472eb70bdba009b8abd3b38db406a5735024ca2f0671586a1e5b4b57a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9299003481864929}",,,,,,,,,,['neutral'],neutral,1 NCT05028582,"{'position': 1, 'link': 'https://www.pharmacytimes.com/view/fda-accepts-snda-of-roflumilast-foam-for-scalp-and-body-psoriasis', 'title': 'FDA Accepts sNDA of Roflumilast Foam for Scalp and Body Psoriasis', 'source': 'Pharmacy Times', 'date': '1 month ago', 'snippet': 'The FDA assigned a Prescription Drug User Fee Act action date of May 22, \n2025.', 'thumbnail': 'https://serpapi.com/searches/6724166a7b05ca376cd59059/images/11aa4b30f5fe9fe15c22bbcca1fb638d3663a7bc3e6cd30eafc425fadcdebd2a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9067659378051758}",,,,,,,,,,['neutral'],neutral,1 NCT03006926,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2020/09/04/fda-rejects-keytruda-lenvima-combo-as-first-line-treatment-for-liver-cancer/', 'title': 'FDA Rejects Keytruda-Lenvima Combo as First-line Treatment for Liver Cancer', 'source': 'Immuno-Oncology News', 'date': 'Sep 4, 2020', 'snippet': 'The U.S. Food and Drug Administration (FDA) has issued a complete response \nletter stating that it will not approve the combination of...', 'thumbnail': 'https://serpapi.com/searches/672416782a7727e9d2444312/images/742113a7ab73c34cfa9866dcf7b0ad89fb6f8fea11705e2f1b464ae67993b64e.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6010357737541199}",,,,,,,,,,['negative'],negative,0 NCT03931681,"{'position': 1, 'link': 'https://news.cuanschutz.edu/cancer-center/onkure-and-cu-cancer-center-announce-first-patient-enrolled-in-clinical-trial-of-oki-179', 'title': 'OnKure and CU Cancer Center announce first patient enrolled in clinical trial of OKI-179, a potent and selective HDAC inhibitor', 'source': 'University of Colorado Anschutz Medical Campus', 'date': 'Jun 17, 2019', 'snippet': 'OnKure, Inc. and the University of Colorado Cancer Center announced \nenrollment of the first patient in a first-in-human phase 1 clinical trial.', 'thumbnail': 'https://serpapi.com/searches/6724167cbd7cf00e347d3124/images/11755ccddec38544219b6b671124055cb02b09c666a21d578362f2f62a5b68bd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.934752345085144}",,,,,,,,,,['neutral'],neutral,1 NCT01757184,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1501365', 'title': 'A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency', 'source': 'The New England Journal of Medicine', 'date': 'Sep 10, 2015', 'snippet': 'Sebelipase alfa therapy resulted in a reduction in multiple disease-related \nhepatic and lipid abnormalities in children and adults with lysosomal acid \nlipase...', 'thumbnail': 'https://serpapi.com/searches/6724179f2da15795533ddf3c/images/65c68207089ea1d4c9bb12d8e15d7e63120cd8057f498ed653d726befb44e4ef.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8553785681724548}",,,,,,,,,,['neutral'],neutral,1 NCT02211209,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1715944', 'title': 'Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome', 'source': 'The New England Journal of Medicine', 'date': 'Aug 7, 2019', 'snippet': 'Familial chylomicronemia syndrome is a rare genetic disorder that is caused \nby loss of lipoprotein lipase activity and characterized by...', 'thumbnail': 'https://serpapi.com/searches/672417afd997ab53a5e9aa0b/images/cb98e0da1cb6cae4392f5c1d7241ffbd78ad5cef6883e9699671b1b0b7a2248d.png', 'sentiment': 'negative', 'sentiment_prob': 0.6402949094772339}",,,,,,,,,,['negative'],negative,0 NCT03953235,"{'position': 1, 'link': 'https://www.globenewswire.com/en/news-release/2024/04/15/2862633/0/en/Nature-Medicine-Publishes-Interim-Results-from-Gritstone-bio-s-Phase-1-2-Study-of-Off-the-Shelf-Neoantigen-Vaccine-Platform-SLATE.html', 'title': 'Nature Medicine Publishes Interim Results from Gritstone', 'source': 'GlobeNewswire', 'date': 'Apr 15, 2024', 'snippet': ""Paper details vaccine design optimization process of Gritstone's \n“off-the-shelf” or shared neoantigen vaccine platform, SLATE."", 'thumbnail': 'https://serpapi.com/searches/672417c3ee4682bcbcfc474a/images/50a7ea1a101bce8197f4ed733401bc1c8d8656dc04ccaebc9ccc21cfb874be66.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9221785068511963}",,,,,,,,,,['neutral'],neutral,1 NCT02277743,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1610020', 'title': 'Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis', 'source': 'The New England Journal of Medicine', 'date': 'Oct 1, 2016', 'snippet': 'In two randomized, placebo-controlled, phase 3 trials of identical design \n(SOLO 1 and SOLO 2), we enrolled adults with moderate-to-severe...', 'thumbnail': 'https://serpapi.com/searches/672417f64791c47929720b04/images/25c230bead31c862548675d72c27e3fd661da4532b2f2741a29a0703bcde16bb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8945711851119995}","{'position': 2, 'link': 'https://www.researchgate.net/publication/377449873_Efficacy_Comparison_of_Targeted_Systemic_Monotherapies_Including_Lebrikizumab_for_Moderate-to-Severe_Atopic_Dermatitis_a_Network_Meta-Analysis', 'title': 'Moderate to- Severe Atopic Dermatitis: a Network Meta Analysis', 'source': 'ResearchGate', 'date': 'Jan 19, 2024', 'snippet': 'PDF | Background: Atopic dermatitis (AD) is a chronic inflammatory skin \ndisease affecting 2–7% of adults globally, with 30% experiencing.', 'thumbnail': 'https://serpapi.com/searches/672417f64791c47929720b04/images/25c230bead31c8628c3394e6344bbc9b4985e196b3db34c4f435b5354a41d579.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5824444890022278}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00672191,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-022-01007-w', 'title': 'mRNA-based therapeutics: powerful and versatile tools to combat diseases | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'May 21, 2022', 'snippet': 'The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat \na wide range of incurable diseases. Recent rapid advances in...', 'thumbnail': 'https://serpapi.com/searches/672417fbdc969fad1f5ae655/images/6f5ef6ae6c30f43ebc72cf5ce58854c63014adc1d812db4b0db524b585547b39.png', 'sentiment': 'positive', 'sentiment_prob': 0.7752447724342346}",,,,,,,,,,['positive'],positive,1 NCT02644668,"{'position': 1, 'link': 'https://smanewstoday.com/ck-2127107-ck-107/', 'title': 'Reldesemtiv for SMA', 'source': 'SMA News Today', 'date': 'Aug 16, 2024', 'snippet': 'Reldesemtiv (formerly CK-2127107) was being developed by Cytokinetics to \ntreat spinal muscular atrophy and ALS.', 'thumbnail': 'https://serpapi.com/searches/67241814f9f904be0f459556/images/e24d6322f11e68e83410237d06377c9d806717570ba955d0cda9300a94eda401.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9099122881889343}",,,,,,,,,,['neutral'],neutral,1 NCT05271552,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/on-demand-bxcl501-seen-ease-alzheimers-agitation-phase-3-trial/', 'title': ""BXCL501 seen to ease Alzheimer's agitation in Phase 3 trial |..."", 'source': ""Alzheimer's News Today"", 'date': 'Jun 30, 2023', 'snippet': ""On-demand treatment with BXCL501 was found to significantly ease episodes \nof agitation for Alzheimer's patients in a Phase 3 clinical trial."", 'thumbnail': 'https://serpapi.com/searches/67241816f8b05d9e91665be5/images/90f1fa62ebba5dea07f603471be23d688707c7522400eb95fe60af045d65c2b8.png', 'sentiment': 'positive', 'sentiment_prob': 0.5488898754119873}",,,,,,,,,,['positive'],positive,1 NCT04073602,"{'position': 1, 'link': 'https://www.onclive.com/view/disitamab-vedotin-shows-efficacy-in-her2-negative-metastatic-urothelial-carcinoma', 'title': 'Disitamab Vedotin Shows Efficacy in HER2-Negative Metastatic Urothelial Carcinoma', 'source': 'OncLive', 'date': 'Jun 30, 2022', 'snippet': 'Disitamab vedotin (RC48-ADC) demonstrated promising efficacy with a \ntolerable safety profile in patients with HER2-negative metastatic \nurothelial carcinoma.', 'thumbnail': 'https://serpapi.com/searches/67241824e92456ab794d42cf/images/f672edf9049ee52c712ca9847d3a3c1f642f0747732eef24a59cbfb9ce4f710f.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6696291565895081}",,,,,,,,,,['positive'],positive,1 NCT03347279,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2034975', 'title': 'Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma', 'source': 'The New England Journal of Medicine', 'date': 'May 12, 2021', 'snippet': 'We conducted a phase 3, multicenter, randomized, double-blind, \nplacebo-controlled trial. Patients (12 to 80 years of age) were randomly...', 'thumbnail': 'https://serpapi.com/searches/67241868d364b4f6c8975ad2/images/0dc1473abb6c3984b05a030a5b56a2992c7f6f038b469d31127a9c33252615e0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8530923128128052}",,,,,,,,,,['neutral'],neutral,1 NCT04770220,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/alz-801-sustains-cognition-2-year-early-alzheimers-trial-data/', 'title': 'ALZ-801 for 2 years seen to sustain cognition in early Alzheimer’s...', 'source': ""Alzheimer's News Today"", 'date': 'Sep 22, 2023', 'snippet': ""Two years of oral ALZ-801 sustained cognition and lower levels of \ndisease-related biomarkers in early Alzheimer's patients with APOE4..."", 'thumbnail': 'https://serpapi.com/searches/6724187f5ddfba8fdaa1fefb/images/b2e281e64f04fcce6921af0423ddca72829625a5471fa90fb65fd001dd7a39a3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6040478348731995}",,,,,,,,,,['neutral'],neutral,1 NCT03803007,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/abs/10.1161/SVIN.03.suppl_2.006', 'title': 'Abstract 006: Glenzocimab Is Associated With Less Haemorrhagic Transformation Using Artificial Intelligence Imaging In Mechanical Thrombectomy Patients', 'source': 'American Heart Association Journals', 'date': 'Nov 10, 2023', 'snippet': 'IntroductionLesion volume measurement provides an objective and \nquantitative assessment of stroke severity and it is often used as a...', 'thumbnail': 'https://serpapi.com/searches/672418813ad34db6889491c3/images/bf1b37174f51dd2520590d046966d6e8f5530f5874d3b77ad4c52ed86bd688b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9045994877815247}",,,,,,,,,,['neutral'],neutral,1 NCT01556776,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/news/lenalidomide-chronic-leukemia-phase-3-cllm1-trial-treatment-risk/', 'title': 'Lenalidomide Maintenance Therapy Linked With B-Cell Acute Lymphoblastic Leukemia in Patients With Chronic Lymphocytic Leukemia', 'source': 'Hematology Advisor', 'date': 'Mar 25, 2021', 'snippet': 'Study of 3 patients from phase 3 CLLM1 trial, researchers showed a link to \nthe development of B-cell ALL with lenalidomide treatment for...', 'thumbnail': 'https://serpapi.com/searches/67241893b5ecbb920ddedc16/images/60e5dd725a8fb92d6a652430f8fb335f8d89b9de81fc607f781ba4d96023cdf7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9085406064987183}",,,,,,,,,,['neutral'],neutral,1 NCT03708328,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-021-00868-x', 'title': 'Emerging new therapeutic antibody derivatives for cancer treatment | Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': '٠٧\u200f/٠٢\u200f/٢٠٢٢', 'snippet': 'In this review, we summarize antibodies of various molecular types, \nantibody applications in cancer therapy, and details of clinical study \nadvances.', 'thumbnail': 'https://serpapi.com/searches/6724189fd997ab53a5e9aa4c/images/1650d23dcc72a9481aba531f07e913b71b51febd30823599b22140bbc751ce53.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8890555500984192}",,,,,,,,,,['neutral'],neutral,1 NCT01194570,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1606468', 'title': 'Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Dec 21, 2016', 'snippet': 'Among patients with primary progressive multiple sclerosis, ocrelizumab was \nassociated with lower rates of clinical and MRI progression than placebo.', 'thumbnail': 'https://serpapi.com/searches/672418a9ba114203b64bb2d6/images/165140e2601530380e5a9c511ba845cf3c4cad697f50ca6b3f396c0f7949fbc0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8376652002334595}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/ocrevus-ocrelizumab-primary-progressive-relapsing-multiple-sclerosis/', 'title': 'Ocrevus (Ocrelizumab) for MS: Uses, Side Effects, and More', 'source': 'Multiple Sclerosis News Today', 'date': 'Mar 17, 2022', 'snippet': 'Ocrevus (ocrelizumab) is a disease-modifying therapy for PPMS and relapsing \nMS. Learn more about its uses, indications, and side effects.', 'thumbnail': 'https://serpapi.com/searches/672418a9ba114203b64bb2d6/images/165140e260153038fa519856bd0cf48e02647dceaa06619bbc8b4b360c5168c9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9069978594779968}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2020/04/28/new-6-year-data-for-genentechs-ocrevus-ocrelizumab-show-earlier-treatment-initiation-nearly-halves-risk-of-needing-walking-aid-in-relapsing-multiple-sclerosis/', 'title': 'Ocrevus in MS Trials Seen to Lower Need for Walking Aid Over 6 Years', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 29, 2020', 'snippet': 'Data at 6 years show relapsing MS patients who started on Ocrevus in trials \nless likely to attain a 6.0 EDSS score than those who switched...', 'thumbnail': 'https://serpapi.com/searches/672418a9ba114203b64bb2d6/images/165140e2601530385511df390b34d6400992e50f66285b5feb1789aeae847962.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7668011784553528}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT00203112,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/minocycline-for-rrms/', 'title': 'Minocycline in MS | Experimental MS Treatments', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 6, 2022', 'snippet': 'Minocycline is an oral antibiotic being evaluated as a potential treatment \nfor MS. Learn more about its uses, side effects, and clinical...', 'thumbnail': 'https://serpapi.com/searches/672418ab9f8bfc44aaac8a80/images/0473df366c037d9290b78b7c552d5e2e8f6764821787c5ec6884a61f6bb2ffb2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9326553344726562}",,,,,,,,,,['neutral'],neutral,1 NCT02231866,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-024-00833-z', 'title': 'Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials', 'source': 'Nature', 'date': 'Mar 29, 2024', 'snippet': 'Ebola virus disease (EVD) is a filoviral infection caused by virus species \nof the Ebolavirus genus including Zaire ebolavirus (EBOV) and...', 'thumbnail': 'https://serpapi.com/searches/672418bfefad2183fae89c4d/images/fbce37e792eeafb6f8ef932751d86d2fd22a9e74eee07b8765904d9d1e99d5f6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.788805365562439}",,,,,,,,,,['neutral'],neutral,1 NCT03084926,"{'position': 1, 'link': 'https://ascopubs.org/doi/10.1200/JCO.20.00596', 'title': 'First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors', 'source': 'ASCO Publications', 'date': 'Dec 10, 2020', 'snippet': 'PURPOSEA first-in-human study was performed with MP0250, a DARPin drug \ncandidate. MP0250 specifically inhibits both vascular endothelial...', 'thumbnail': 'https://serpapi.com/searches/672418cb48b9f7f46b775d07/images/e6b6f08e5e75547c47b31b52129b1d90f930168e627717a7319230594d9f60d9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9029291272163391}",,,,,,,,,,['neutral'],neutral,1 NCT02857569,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-0994-4', 'title': 'Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectives', 'source': 'Nature', 'date': 'Jul 27, 2020', 'snippet': 'The emergence of human intratumoural immunotherapy (HIT-IT) is a major step \nforward in the management of unresectable melanoma.', 'thumbnail': 'https://serpapi.com/searches/672418e20197dd4da32e65aa/images/00e871fe0e17aeaf6e8762ae9ccd4f24ed4f6ecfe1fe6c7ed1ec69808d42a4ab.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8569298386573792}",,,,,,,,,,['neutral'],neutral,1 NCT03517176,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-21858-1', 'title': 'Tumor-penetrating therapy for β5 integrin-rich pancreas cancer', 'source': 'Nature', 'date': 'Mar 9, 2021', 'snippet': 'Pancreatic ductal adenocarcinoma (PDAC) is characterized by marked \ndesmoplasia and drug resistance due, in part, to poor drug delivery to...', 'thumbnail': 'https://serpapi.com/searches/672418fb0197dd4da32e65ad/images/66e5c8d3afc7a68b27379e7afb1ba6a658e86a005b3e9e140045dc7a9c74c932.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6579923033714294}",,,,,,,,,,['negative'],negative,0 NCT01568099,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/experimental-treatments/affitope-pd01a/', 'title': 'ACI-7104 for Parkinson’s disease', 'source': ""Parkinson's News Today"", 'date': 'Jun 14, 2024', 'snippet': 'Last updated June 14, 2024, by Marta Figueiredo, PhD ✓ Fact-checked by Ana \nde Barros, PhD. How ACI-7104 works. Administration. Clinical trials. Side \neffects...', 'thumbnail': 'https://serpapi.com/searches/6724192648c429ecf8b683ef/images/d3faf14b8bd33cabcbb9e0387c3889bccd7304735fb09f37e38a1d6d95955df8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9401443600654602}",,,,,,,,,,['neutral'],neutral,1 NCT02101385,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/triple-negative-breast-cancer-ngs-guided-therapy-did-not-improve-outcomes/', 'title': 'NGS-Guided Therapy Did Not Improve Outcomes in Triple-Negative Breast Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Jan 10, 2022', 'snippet': 'Genomically directed therapy did not improve outcomes in patients who had \nresidual triple-negative breast cancer after neoadjuvant...', 'thumbnail': 'https://serpapi.com/searches/6724193b81bab7b8fdf0d64f/images/387a45fe1048c53f4764349a9597a106299a923129e81231bada2f5b1720d939.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8586665391921997}",,,,,,,,,,['negative'],negative,0 NCT05086276,"{'position': 1, 'link': 'https://www.genengnews.com/topics/drug-discovery/stockwatch-regenerons-all-ears-for-hearing-loss-drug-developer/', 'title': 'StockWatch: Regeneron’s All Ears for Hearing Loss Drug Developer', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Aug 11, 2023', 'snippet': 'Decibel Therapeutics finds a buyer as Regeneron Pharmaceuticals agrees to \nbuy the hearing loss drug developer for up to $213 million.', 'thumbnail': 'https://serpapi.com/searches/6724195e2da15795533ddf8e/images/a72b163cfa7d4c008b0f7c4325c8212d34403a554287696a8dfcad7c977cde58.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8836510181427002}","{'position': 2, 'link': 'https://www.genengnews.com/gen-edge/frequency-change-korro-bio-edits-its-message-rewrites-its-future-with-reverse-merger/', 'title': 'Frequency Change: Korro Bio Edits Its Message, Rewrites Its Future with Reverse Merger', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Aug 7, 2023', 'snippet': 'Korro Bio plans a reverse merger with Frequency Therapeutics to fund \nclinical studies of its lead candidate, designed to treat alpha-1...', 'thumbnail': 'https://serpapi.com/searches/6724195e2da15795533ddf8e/images/a72b163cfa7d4c00157e32282589b1d9d59e16ad55a889ddd8d165ba1756d6a8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8689308762550354}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04577404,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/mitsubishi-tanabe-pharma-america-presents-new-results-of-radicava-edaravone-for-people-living-with-als-at-the-european-network-to-cure-als-encals-meeting-2024-302172441.html', 'title': 'Mitsubishi Tanabe Pharma America Presents New Results of RADICAVA® (edaravone) for People Living with ALS at the European Network to Cure ALS (ENCALS) Meeting 2024', 'source': 'PR Newswire', 'date': 'Jun 17, 2024', 'snippet': 'PRNewswire/ -- Mitsubishi Tanabe Pharma America, Inc. (MTPA) today \nannounced results from two studies of RADICAVA® (edaravone) for...', 'thumbnail': 'https://serpapi.com/searches/67241a17efad2183fae89c9b/images/874490850a28bec464189434bf5108dff595c33b214b4f41d391d8be0bb5e8f2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9170039296150208}",,,,,,,,,,['neutral'],neutral,1 NCT04871711,"{'position': 1, 'link': 'https://nationaleczema.org/blog/leo-12622/', 'title': 'LEO Pharma Announces Positive Phase 3 Topline Results From DELTA 1 Trial With Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (CHE)', 'source': 'National Eczema Association', 'date': 'Dec 6, 2022', 'snippet': 'The first phase 3 clinical trial (DELTA 1) with delgocitinib cream in \nadults with moderate to severe chronic hand eczema (CHE) met primary...', 'thumbnail': 'https://serpapi.com/searches/67241a3571c62b8d36d253c4/images/fc6366bf096c5a59eb290de56a4e9feda6c15f029a318afb60a6773209cc2250.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5227524638175964}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/delgocitinib-cream-significantly-improves-chronic-hand-eczema-in-trial/', 'title': 'Delgocitinib Cream Significantly Improves Chronic Hand Eczema in Trial', 'source': 'Medical Professionals Reference', 'date': 'Dec 6, 2022', 'snippet': 'Delgocitinib cream significantly improved chronic hand eczema in adult \npatients, according to topline results from the DELTA 1 study.', 'thumbnail': 'https://serpapi.com/searches/67241a3571c62b8d36d253c4/images/fc6366bf096c5a59f568b1998490d90e8fa2447de3e81d1613b900daa18a5127.png', 'sentiment': 'positive', 'sentiment_prob': 0.8139118552207947}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02643862,"{'position': 1, 'link': 'https://www.thelancet.com/journals/langas/article/PIIS2468-1253(17)30392-8/fulltext?elsca1=tlpr', 'title': 'Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial', 'source': 'The Lancet', 'date': 'Dec 11, 2017', 'snippet': 'We did a pilot study testing whether anti-IgE (omalizumab) combined with \nmultifood oral immunotherapy benefited multifood allergic patients.', 'thumbnail': 'https://serpapi.com/searches/67241a3eb691a7ace56a85f8/images/ad9b5c776c1e2b6e1d6d9f8d6e1fea8fd732edf27d70183e593db8539e02cdc3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8796260952949524}",,,,,,,,,,['neutral'],neutral,1 NCT00846040,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/eating-habits-body-fat-related-differences-brain-chemistry', 'title': 'Eating habits, body fat related to differences in brain chemistry', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Sep 9, 2014', 'snippet': 'NIH study ties eating in response to food cues to habit-forming region in \nobese adults.', 'thumbnail': 'https://serpapi.com/searches/67241a48708e2e993b0dde62/images/a8c60ea0a81d2212f8d565e76be060c597a20f4ac8765965ad8c203977d8ca2b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9214413166046143}",,,,,,,,,,['neutral'],neutral,1 NCT04569435,"{'position': 1, 'link': 'https://alsnewstoday.com/news/annexon-anx005-slows-als-progression-phase-2-study/', 'title': ""Annexon's ANX005 Slows ALS Progression in Phase 2a Study"", 'source': 'ALS News Today', 'date': 'Jan 13, 2023', 'snippet': ""ANX005, Annexon Biosciences' lead experimental medication, slowed disease \nprogression in adults with ALS, study results show."", 'thumbnail': 'https://serpapi.com/searches/67241a60e1d1adc069a08148/images/c3997f2c269b61cf8616fa79c7daa82afd2612a80f0749e58ada0ae673317781.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6895772814750671}",,,,,,,,,,['neutral'],neutral,1 NCT04886622,"{'position': 1, 'link': 'https://www.nature.com/articles/s41420-022-01296-8', 'title': 'Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice | Cell Death Discovery', 'source': 'Nature', 'date': 'Jan 2, 2023', 'snippet': 'Small-cell lung cancer (SCLC) is an aggressive malignancy with limited \ntherapeutic options. The dismal prognosis in SCLC is in part...', 'thumbnail': 'https://serpapi.com/searches/67241a62ce1e10a40aec6650/images/e55c15a0e37e8d0703fb2f8aa59fe81e0e55ffa37cbc90ba75e454fa8dee2bf6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6004174947738647}",,,,,,,,,,['neutral'],neutral,1 NCT02795429,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-00264-x', 'title': 'Targeted therapy for hepatocellular carcinoma - Signal Transduction and Targeted Therapy', 'source': 'Nature', 'date': 'Aug 11, 2020', 'snippet': 'The last 3 years have seen the emergence of promising targeted therapies \nfor the treatment of hepatocellular carcinoma (HCC).', 'thumbnail': 'https://serpapi.com/searches/67241a692c83d5b81af4c6c4/images/5a5b8df2aab3ffb3620a95ab8d29bbf41645ccbe523a7397422e3191cb319fe3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6826193332672119}",,,,,,,,,,['neutral'],neutral,1 NCT05136885,"{'position': 1, 'link': 'https://alsnewstoday.com/news/enrollment-complete-als-phase-2-3-trial-sls-005/', 'title': 'Enrollment complete in HEALEY Phase 2/3 trial arm of SLS-005', 'source': 'ALS News Today', 'date': 'Feb 15, 2023', 'snippet': 'Seelos Therapeutics has completed patient enrollment in its Phase 2/3 \nclinical trial evaluating SLS-005 as a treatment for ALS.', 'thumbnail': 'https://serpapi.com/searches/67241a73c117a94b2401b8f6/images/322240eeb7344601b8688c4005e6c7b3e83afab82f8ed9da50414ea50a9dd0cc.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8740873336791992}","{'position': 2, 'link': 'https://alsnewstoday.com/news/expanded-access-program-sls-005-trehalose-dosing/', 'title': 'Expanded access program for SLS-005 begins treating first ALS patient', 'source': 'ALS News Today', 'date': 'Apr 11, 2023', 'snippet': 'An expanded access program treating ALS patients ineligible for clinical \ntrials with SLS-005, containing trehalose, has dosed a first...', 'thumbnail': 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BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma', 'source': 'Nature', 'date': 'May 8, 2020', 'snippet': 'Chimeric antigen receptor (CAR)-T cell therapy has shown remarkable \nclinical efficacy against B-cell malignancies, yet marked vulnerability...', 'thumbnail': 'https://serpapi.com/searches/67241a7d9fd3095e762f9325/images/d1ebc42727554aace315afe703a3d087bea1a7f89b1819a9ac053e705c50e386.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7855530977249146}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02955355,"{'position': 1, 'link': 'https://www.empr.com/home/news/hyqvia-reduces-relapse-in-chronic-inflammatory-demyelinating-polyradiculoneuropathy-trial/', 'title': 'Hyqvia Reduces Relapse in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Trial', 'source': 'Medical Professionals Reference', 'date': 'Jul 21, 2022', 'snippet': 'Topline data were announced from a phase 3 trial evaluating the efficacy \nand safety of Hyqvia® (immune globulin infusion 10% [human] with...', 'thumbnail': 'https://serpapi.com/searches/67241a88f8b05d9ece9f1798/images/902a7492ce0211fa475c739fb30e76e7a94909e81f5a3d4e03b5c087d085d402.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7634502649307251}",,,,,,,,,,['neutral'],neutral,1 NCT01757535,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2004444', 'title': 'Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission', 'source': 'The New England Journal of Medicine', 'date': 'Dec 23, 2020', 'snippet': 'We conducted a phase 3, randomized, double-blind, placebo-controlled trial \nof the oral formulation of azacitidine (CC-486, a hypomethylating...', 'thumbnail': 'https://serpapi.com/searches/67241a895235f60c4e295b9d/images/5ee9c1a6d940b411c194092d81104f9a916423786176bc92cb2504d40d592302.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9053488969802856}","{'position': 2, 'link': 'https://www.cancertherapyadvisor.com/news/leukemia-aml-oral-azacitidine-maintenance-therapy-post-remission-new-standard/', 'title': 'Postremission Oral Azacitidine Maintenance Therapy Proposed As a New Standard of Care in Some Patients With AML', 'source': 'Cancer Therapy Advisor', 'date': 'Dec 12, 2019', 'snippet': 'Eligibility criteria for this study included intermediate- or high-risk \ncytogenetics, and CR or CR with incomplete count recovery following...', 'thumbnail': 'https://serpapi.com/searches/67241a895235f60c4e295b9d/images/5ee9c1a6d940b411118aa402cda231e6c320dfaa446f86257341ed016022bcc8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8953773975372314}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02908685,"{'position': 1, 'link': 'https://smanewstoday.com/news/british-columbia-funds-evrysdi-canadian-province-sma-patients/', 'title': 'Evrysdi for SMA Patients in British Columbia Being Offered at No Cost', 'source': 'SMA News Today', 'date': 'Feb 21, 2022', 'snippet': 'The provincial government of British Columbia will cover the cost of \nEvrysdi (risdiplam), the oral spinal muscular atrophy (SMA) therapy \napproved by Health...', 'thumbnail': 'https://serpapi.com/searches/6724199e23a4b5ab47584d11/images/47b58a4ae3852300ced0592d2a80d43305847ff5d47752da3002b2447911ac3a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9134345054626465}","{'position': 2, 'link': 'https://smanewstoday.com/evrysdi-risdiplam/', 'title': 'Evrysdi (risdiplam) for spinal muscular atrophy', 'source': 'SMA News Today', 'date': 'Aug 8, 2020', 'snippet': 'Evrysdi (risdiplam) is a daily disease-modifying therapy approved for \nchildren and adults with spinal muscular atrophy (SMA).', 'thumbnail': 'https://serpapi.com/searches/6724199e23a4b5ab47584d11/images/47b58a4ae3852300a14bbbdd11d89a2b2ae4f359390c2235861dfed463efed3e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8439708948135376}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03834688,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/twenty-years-of-advancing-discoveries-and-treatment-of-mantle-cell-lymphoma', 'title': 'Twenty Years of Advancing Discoveries and Treatment of Mantle Cell Lymphoma', 'source': 'Cancer Network', 'date': 'Feb 8, 2024', 'snippet': 'In 2023, the Lymphoma Research Foundation hosted the Mantle Cell Lymphoma \nScientific Consortium and Workshop to discuss treatment...', 'thumbnail': 'https://serpapi.com/searches/6724199f740bdbfb13b90964/images/f7420c77fee35091b8d888e81b8b0d69853000fb8f37343b831294175a84b2eb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8921674489974976}",,,,,,,,,,['neutral'],neutral,1 NCT04013672,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.966696/full', 'title': 'Efficacy and safety of innate and adaptive immunotherapy combined with standard of care in high-grade gliomas: a systematic review and meta-analysis', 'source': 'Frontiers', 'date': 'Feb 6, 2024', 'snippet': 'BackgroundMalignant glioma is the most common intracranial malignant tumor \nwith the highest mortality. In the era of immunotherapy, it is important \nto...', 'thumbnail': 'https://serpapi.com/searches/67241a9a577da558bd156c65/images/c2b309afd07520d97f9e4048cfdbab2187e2635a8bdbbb8f46183270679df7d1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8517996072769165}",,,,,,,,,,['neutral'],neutral,1 NCT02871791,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-024-45835-6', 'title': 'Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial', 'source': 'Nature', 'date': 'Mar 19, 2024', 'snippet': 'Here we present the final results of a phase Ib/IIa, open-label trial \n(NCT02871791) of exemestane plus everolimus and palbociclib for \nCDK4/6i-resistant...', 'thumbnail': 'https://serpapi.com/searches/67241aa9175de69837edd3ea/images/5a0570c9a46ce9fc347ccef630e50421fe671f926318dd4bb4a3d312c685ac23.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9008781313896179}",,,,,,,,,,['neutral'],neutral,1 NCT00514683,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1103690', 'title': 'Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'Apr 30, 2018', 'snippet': 'BIBF 1120 is a potent intracellular inhibitor of tyrosine kinases that is \nin clinical development for the treatment of idiopathic pulmonary fibrosis \nand a...', 'thumbnail': 'https://serpapi.com/searches/67241abe49ea5508c8ff20c3/images/eba38665fe5102603944b41a007653b6e1613eb1346ce922e33ee8cb8e0eef35.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8839802145957947}","{'position': 2, 'link': 'https://lungdiseasenews.com/2017/10/24/analysis-shows-ofev-improves-long-term-lung-function-of-pulmonary-fibrosis-patients/', 'title': ""IPF Patients' Long-term Lung Function Improves with Ofev, Study Shows"", 'source': 'Lung Disease News', 'date': 'Oct 24, 2017', 'snippet': ""Read about a Phase 2 trial and extension showing that Ofev improves \npulmonary fibrosis patients' long-term lung function and reduces their..."", 'thumbnail': 'https://serpapi.com/searches/67241abe49ea5508c8ff20c3/images/eba38665fe5102601a90c353032baaf23262f34fd6578c4c3698a4af24a9a0c0.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6028978228569031}","{'position': 3, 'link': 'https://pulmonaryfibrosisnews.com/news/ipf-patients-live-longer-on-nintedanib-pooled-data-from-six-trials-show/', 'title': 'IPF Patients Live Longer on Ofev Compared with Placebo, Analysis Shows', 'source': 'Pulmonary Fibrosis News', 'date': 'Apr 16, 2019', 'snippet': 'Treatment with Ofev (nintedanib) can significantly extend the survival of \npatients with idiopathic pulmonary fibrosis (IPF), an analysis of pooled \ndata from...', 'thumbnail': 'https://serpapi.com/searches/67241abe49ea5508c8ff20c3/images/eba38665fe510260653217e684fdb71399d6facac13dc28bf028bbe41a3fa1c9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.544462263584137}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT02981407,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2307983', 'title': 'Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia', 'source': 'The New England Journal of Medicine', 'date': 'Nov 11, 2023', 'snippet': 'A strategy of administering a transfusion only when the hemoglobin level \nfalls below 7 or 8 g per deciliter has been widely adopted. However, \npatients with...', 'thumbnail': 'https://serpapi.com/searches/67241ac3be1497ff0398f231/images/bea366c3442a5a23cc5a1b7d41a54aa45e53717df7f8dd52b4ceda4ce21bffea.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8786980509757996}","{'position': 2, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.057909', 'title': 'One-Year Major Cardiovascular Events After Restrictive Versus Liberal Blood Transfusion Strategy in Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Trial', 'source': 'American Heart Association Journals', 'date': 'Feb 7, 2022', 'snippet': 'Uncertainty exists on the optimal transfusion strategy in patients with \nanemia and acute myocardial infarction (AMI). Observational studies...', 'thumbnail': 'https://serpapi.com/searches/67241ac3be1497ff0398f231/images/bea366c3442a5a236762ca4d77f55896481f12ceb09f6d45a9e9075250331ef9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6346853971481323}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04506463,"{'position': 1, 'link': 'https://www.pharmaceutical-technology.com/news/sun-pharma-moebius-osteoarthritis-treatment/', 'title': 'Sun Pharma and Moebius gain FDA fast track for osteoarthritis drug', 'source': 'Pharmaceutical Technology', 'date': '1 month ago', 'snippet': 'Sun Pharma and Moebius Medical have received fast track designation (FTD) \nfrom the US Food and Drug Administration (FDA) for MM-II.', 'thumbnail': 'https://serpapi.com/searches/67241afe93584c2b3cbbffd0/images/37bacbd5acdc84aa7b416b63538d900ce436885100e31a1908de7c9e1df10d08.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5669798254966736}","{'position': 2, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332223016177', 'title': 'Harnessing the multifunctionality of lipid-based drug delivery systems for the local treatment of osteoarthritis', 'source': 'ScienceDirect.com', 'date': 'Nov 7, 2023', 'snippet': 'This review emphasizes recent advancements in lipid-based drug delivery \nsystems (DDSs) for intra-articular administration of OA therapeutics.', 'thumbnail': 'https://serpapi.com/searches/67241afe93584c2b3cbbffd0/images/37bacbd5acdc84aaeb13b8861ba9783211dbfdc7b9e1d8ee3c5ce40bf13e0b0a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.650626003742218}","{'position': 3, 'link': 'https://www.biospectrumasia.com/news/25/24855/israels-moebius-medical-indias-sun-pharma-receive-fast-track-designation-for-osteoarthritis-knee-pain-medicine.html', 'title': ""Israel's Moebius Medical & India's Sun Pharma receive fast track designation for osteoarthritis knee pain medicine"", 'source': 'BioSpectrum Asia', 'date': '1 month ago', 'snippet': 'The US Food and Drug Administration (FDA) has granted Fast Track \ndesignation (FTD) to MM-II (Large Liposomes of DPPC and DMPC) for the \ntreatment of...', 'thumbnail': 'https://serpapi.com/searches/67241afe93584c2b3cbbffd0/images/37bacbd5acdc84aa6475b177e784ee961b9b15478c8b3a94559390c6f83d4956.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8736117482185364}","{'position': 4, 'link': 'https://www.expresspharma.in/data-shows-durability-of-pain-relief-for-patients-with-knee-osteoarthritis-oa/', 'title': 'Data shows durability of pain relief for patients with knee osteoarthritis (OA)', 'source': 'Express Pharma', 'date': 'Jun 14, 2024', 'snippet': 'Sun Pharmaceutical Industries, (including its subsidiaries or associate \ncompanies) and Israel-based Moebius Medical presented data...', 'thumbnail': 'https://serpapi.com/searches/67241afe93584c2b3cbbffd0/images/37bacbd5acdc84aad92c73634eef18d90f42e12b551d34a69d34223ec559bc02.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8590989112854004}","{'position': 5, 'link': 'https://www.indianpharmapost.com/drug-approval/sun-pharma-and-moebius-medical-granted-ftd-to-mm-ii-for-treatment-of-osteoarthritis-knee-pain-16140', 'title': 'Sun Pharma and Moebius Medical granted FTD to MM-II for treatment of osteoarthritis knee pain', 'source': 'Indian Pharma Post', 'date': '1 month ago', 'snippet': 'The US Food and Drug Administration (FDA) has granted Fast Track \nDesignation (FTD) to MM-II (Large Liposomes of DPPC and DMPC) for the \ntreatment of...', 'thumbnail': 'https://serpapi.com/searches/67241afe93584c2b3cbbffd0/images/37bacbd5acdc84aa6c314f2057f7bf39d5ba263c848cf8a9907e69aa944f314a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9046306014060974}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01270074,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/azithromycin-reduces-airway-wall-thickness-infants-study/', 'title': 'Azithromycin reduces airway wall thickness in infants: Study', 'source': 'Cystic Fibrosis News Today', 'date': 'May 3, 2024', 'snippet': 'Azithromycin reduces bronchial wall thickening in CF infants, which may \ntranslate into smoother blood flow to the lungs, per a study.', 'thumbnail': 'https://serpapi.com/searches/67241b2d2da983780b740e3a/images/c6c8f287aa418a1c74eca699b090d511e51d5d07ffb6482ec04e452878a68892.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8316199779510498}",,,,,,,,,,['neutral'],neutral,1 NCT04199169,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-022-00592-9', 'title': 'ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys', 'source': 'Nature', 'date': 'Dec 21, 2022', 'snippet': 'Nipah virus (NiV) is a highly pathogenic and re-emerging virus, which \ncauses sporadic but severe infections in humans.', 'thumbnail': 'https://serpapi.com/searches/67241b2ff60b6f8f33efe72d/images/d2addc037f3d02885e09b14b206917be6b642e3546fad56afa282ddc027c487a.png', 'sentiment': 'negative', 'sentiment_prob': 0.5253660678863525}",,,,,,,,,,['negative'],negative,0 NCT02274766,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-022-00291-1', 'title': 'Amantadine delayed release/extended release capsules significantly reduce OFF time in Parkinson’s disease', 'source': 'Nature', 'date': 'Mar 18, 2022', 'snippet': 'An amantadine delayed release/extended release (DR/ER) formulation (Gocovri \n® ) indicated for dyskinesia received additional FDA approval as an adjunct \nto...', 'thumbnail': 'https://serpapi.com/searches/67241bba361fd42d611f4c2d/images/4098283d435f6156920733253cfd279809da34f0e7eae2024f4ff285271031a3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6950205564498901}",,,,,,,,,,['neutral'],neutral,1 NCT03461276,"{'position': 1, 'link': 'https://www.neurologylive.com/view/neurovoices-david-greeley-ar1001-oral-pde5-inhibitor-alzheimers', 'title': 'NeuroVoices: David Greeley, MD, on AR1001, an Oral PDE5 Inhibitor for Alzheimer Disease', 'source': 'Neurology live', 'date': 'Nov 1, 2023', 'snippet': 'David Greeley, MD, chief medical officer at AriBio and study author, \nprovided commentary on the mechanism of action of AR1001, its promising...', 'thumbnail': 'https://serpapi.com/searches/67241bcad771bdf678dc5a44/images/8a0c88ac4a8c5b41efa6c12f6edf8b7a137b85a60c9b400c1d2258eaea3119d9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8086296916007996}",,,,,,,,,,['neutral'],neutral,1 NCT02056665,"{'position': 1, 'link': 'https://angelmansyndromenews.com/minocycline/', 'title': 'Angelman Syndrome in Children Improves with Minocycline, Studies Show', 'source': 'Angelman Syndrome News', 'date': 'Nov 19, 2017', 'snippet': 'Read about studies indicating that the antibiotic minocycline can improve \nthe symptoms of children with Angelman syndrome.', 'thumbnail': 'https://serpapi.com/searches/67241bddc5d7698b996f4a6c/images/0420a780ef895e9ec4084cbf654d0f68939a006ed6773d2c29f3539408e93822.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5991294384002686}",,,,,,,,,,['neutral'],neutral,1 NCT02295826,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.119.027569', 'title': 'Dabigatran Treatment of Acute Noncardioembolic Ischemic Stroke', 'source': 'American Heart Association Journals', 'date': 'Feb 26, 2020', 'snippet': 'Background and Purpose—Patients with transient ischemic attack (TIA) and \nminor ischemic stroke are at risk for early recurrent cerebral...', 'thumbnail': 'https://serpapi.com/searches/67241be6b57db8f48f367cae/images/ddc89f7f9b9f640636b8dc9bbb3667aee7851e611ad729b820208d89e99e6bb1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6758471727371216}",,,,,,,,,,['neutral'],neutral,1 NCT01958021,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2114663', 'title': 'Overall Survival with Ribociclib plus Letrozole in Advanced Breast Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Mar 10, 2022', 'snippet': 'In a previous analysis of this phase 3 trial, first-line ribociclib plus \nletrozole resulted in significantly longer progression-free survival than \nletrozole...', 'thumbnail': 'https://serpapi.com/searches/67241c20f59d00c57d4022eb/images/f8fad5df7edf75345adc4184b478ca9daf625346fc522d9e7ce9641db4b41f7d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6093955039978027}","{'position': 2, 'link': 'https://ascopubs.org/doi/10.1200/JCO.20.02977', 'title': 'Correlative Biomarker Analysis of Intrinsic Subtypes and Efficacy Across the MONALEESA Phase III Studies', 'source': 'ASCO Publications', 'date': 'Mar 26, 2021', 'snippet': 'PURPOSEThe prognostic and predictive value of intrinsic subtypes in hormone \nreceptor–positive, human epidermal growth factor receptor...', 'thumbnail': 'https://serpapi.com/searches/67241c20f59d00c57d4022eb/images/f8fad5df7edf75349c60c3054c4cf87211a2d092f90f6c750358bd4116828369.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9209080934524536}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/ribociclib-dose-reductions-maintain-comparable-outcomes-in-hr-her2-negative-advanced-breast-cancer', 'title': 'Comparable Outcomes Maintained With Ribociclib Dose Reductions in HR+/HER2-Negative Advanced Breast Cancer', 'source': 'Cancer Network', 'date': 'Jun 7, 2022', 'snippet': 'Dose reductions of ribociclib administered during the phase 2 MONALEESA-2 \ntrial did not have an impact on overall survival for patients with...', 'thumbnail': 'https://serpapi.com/searches/67241c20f59d00c57d4022eb/images/f8fad5df7edf7534d1d08c16ce41540fb27e120d66d9b5b53eb8527e35d08667.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8730349540710449}","{'position': 4, 'link': 'https://breastcancer-news.com/2017/06/05/kisqali-femara-shows-promise-in-hr-positive-her2-negative-advanced-breast-cancer/', 'title': 'In Certain Advanced Breast Cancer, Kisqali, Femara Combo Shows Promise', 'source': 'breastcancer-news.com', 'date': 'Jun 5, 2017', 'snippet': ""The latest results from the Phase 3 MONALEESA-2 study showed that adding \nNovartis' Kisqali (ribociclib) to \u200eFemara (letrozole) for the..."", 'thumbnail': 'https://serpapi.com/searches/67241c20f59d00c57d4022eb/images/f8fad5df7edf753428859ccec79db0181ae1b00793557e89ec8d3dc3548b7fa9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.779985785484314}","{'position': 5, 'link': 'https://dailynews.ascopubs.org/do/making-sense-paloma-2-and-monaleesa-2-data-treatment-hr-positive-her2-negative', 'title': 'Making Sense of PALOMA-2 and MONALEESA-2 Data for the Treatment of HR-Positive/HER2-Negative Metastatic Breast Cancer', 'source': 'ASCO Daily News', 'date': 'May 3, 2023', 'snippet': 'PALOMA-2 studied palbociclib, MONALEESA-2 studied ribociclib, and MONARCH-3 \nevaluated abemaciclib. The initial results of these pivotal studies—...', 'thumbnail': 'https://serpapi.com/searches/67241c20f59d00c57d4022eb/images/f8fad5df7edf7534dac83d9eef3e39605265b6ef9353b6625e1dd8de3d79b245.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9260327219963074}",,,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT01295827,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1501824', 'title': 'Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Feb 6, 2017', 'snippet': 'We assessed the efficacy and safety of programmed cell death 1 (PD-1) \ninhibition with pembrolizumab in patients with advanced non–small-cell lung \ncancer...', 'thumbnail': 'https://serpapi.com/searches/67241c2b81bab7b92fca1c27/images/f5c239c5aa07451a8c98df74a233132937ba5d433f682f181044a0d3f2829af3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8554887771606445}",,,,,,,,,,['neutral'],neutral,1 NCT01286987,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222008472', 'title': 'PARP inhibitors in small cell lung cancer: The underlying mechanisms and clinical implications', 'source': 'ScienceDirect.com', 'date': 'Jul 23, 2022', 'snippet': 'Since the concept, DNA damage repair has been stated as a natural \nbiological event, and research has increasingly revealed its strong \nassociation to tumors,...', 'thumbnail': 'https://serpapi.com/searches/67241c46b6e4db2835632e9d/images/319b84461322d7964e1577c669dea1797d4ae18474b3c9282e7c2d7083cbb90f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7746975421905518}",,,,,,,,,,['neutral'],neutral,1 NCT03469284,"{'position': 1, 'link': 'https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02579-8', 'title': 'Methylene blue for intractable pain from oral mucositis related to cancer treatment: a randomized phase 2 clinical trial', 'source': 'BMC Medicine', 'date': 'Nov 3, 2022', 'snippet': 'Oral mucositis (OM) in patients receiving cancer therapy is thus far not \nwell managed with standard approaches. We aimed to assess the...', 'thumbnail': 'https://serpapi.com/searches/67241d26adc33b14f874ebd6/images/2723452f1475b8a8a2550db7e76d700f69f97aa392c461caf9181ca86d8f40e0.png', 'sentiment': 'negative', 'sentiment_prob': 0.5885791778564453}",,,,,,,,,,['negative'],negative,0 NCT03341689,"{'position': 1, 'link': 'https://psychedelicalpha.com/news/single-dose-of-psilocybin-reduces-migraines-for-at-least-2-weeks', 'title': 'Single Dose of Psilocybin Reduces Migraines for at Least 2 Weeks', 'source': 'Psychedelic Alpha', 'date': 'Nov 14, 2020', 'snippet': 'New research from Yale finds that a single low dose of psilocybin reduces \nthe frequency of migraine headaches for 2 weeks.', 'thumbnail': 'https://serpapi.com/searches/67241d4421e77bd9839caa8f/images/22008069792cb690eb33d18c4cdccf1c071d0e6020e4d62fc3436d47eddd527d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5920467376708984}",,,,,,,,,,['neutral'],neutral,1 NCT04211740,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/10/13/ectrims-2023-och-shows-promise-treating-spms-small-trial/', 'title': 'ECTRIMS 2023: Treating SPMS with OCH shows promise in small study...', 'source': 'Multiple Sclerosis News Today', 'date': 'Oct 13, 2023', 'snippet': 'Five of six people with secondary progressive MS treated with OCH in a \nsmall clinical trial experienced no disease activity over six months.', 'thumbnail': 'https://serpapi.com/searches/67241c568db376552966162c/images/97f795ac1a8587256cf7b701d651f2c7b7bc5aaeb42e0ab030376060996ee9f7.png', 'sentiment': 'positive', 'sentiment_prob': 0.6194054484367371}",,,,,,,,,,['positive'],positive,1 NCT02436096,"{'position': 1, 'link': 'https://fibromyalgianewstoday.com/2020/09/08/enrollment-open-in-second-phase-3-trial-of-higher-tnx-102-sl-dose-for-managing-fm/', 'title': 'Enrollment Open in Second Phase 3 Trial of Higher TNX-102 SL Dose for Managing FM', 'source': 'Fibromyalgia News Today', 'date': 'Sep 8, 2020', 'snippet': ""The second Phase 3 clinical trial examining a higher dose of TNX-102 SL \n(sublingual cyclobenzaprine), Tonix Pharmaceuticals' bedtime..."", 'thumbnail': 'https://serpapi.com/searches/67241c629819f3cca7de750f/images/4059d25dc2ef9ff422556ee8ed3206b0e720314a1ddf4ab1975189273030f1a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9358941316604614}",,,,,,,,,,['neutral'],neutral,1 NCT02157792,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-021-01405-x', 'title': 'Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours', 'source': 'Nature', 'date': 'May 26, 2021', 'snippet': 'Berzosertib (formerly M6620, VX-970) is a highly potent and selective, \nfirst-in-class inhibitor of ataxia telangiectasia and Rad3-related...', 'thumbnail': 'https://serpapi.com/searches/67241c64cc2987a5b0417be4/images/b6ff5a137e12c94a5eb8be285a97495d522b152b2b33ba7ef0a4e7c9732fcc1f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7692916989326477}","{'position': 2, 'link': 'https://www.targetedonc.com/view/atr-inhibitor-combinations-begin-to-tackle-dna-damage-repair-in-solid-tumors', 'title': 'ATR Inhibitor Combinations Begin to Tackle DNA Damage Repair in Solid Tumors', 'source': 'Targeted Oncology', 'date': 'Dec 17, 2021', 'snippet': ""ATR's integral role in DNA damage repair has made it an appealing target \nfor cancer treatment, and several ATR inhibitors are being..."", 'thumbnail': 'https://serpapi.com/searches/67241c64cc2987a5b0417be4/images/b6ff5a137e12c94af5ce4fd1868e5e6b31d1ef40ee7ba2910a8be9ba2bb41f3e.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5164445042610168}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT02347774,"{'position': 1, 'link': 'https://copdnewstoday.com/news/analyses-phase-3-trials-sun-101-eflow-safe-effective-copd/', 'title': 'Analyses of Phase 3 Trials Show SUN-101/eFlow Safe, Effective for COPD', 'source': 'COPD News Today', 'date': 'Nov 2, 2017', 'snippet': 'Pooled data from three Phase 3 clinical trials shows that the investigative \nSUN-101/eFlow product is well-tolerated and improves lung...', 'thumbnail': 'https://serpapi.com/searches/67241c8890b57c015b7287ca/images/f329bc52528cd40285f0c62462992a1356cd6898d146c7513ff9bf14d304c990.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6960063576698303}","{'position': 2, 'link': 'https://copdnewstoday.com/news/new-drug-application-sunovion-copd-therapy-accepted-fda/', 'title': 'New Drug Application for Sunovion’s COPD Therapy Accepted by FDA', 'source': 'COPD News Today', 'date': 'Oct 20, 2016', 'snippet': ""Read about the FDA acceptance of a New Drug Application for Sunovion's COPD \ntreatment SUN-101 delivered with the eFlow nebulizer."", 'thumbnail': 'https://serpapi.com/searches/67241c8890b57c015b7287ca/images/f329bc52528cd402341bdfb8ad0f937b33a2a84be842750c442f6ad450777788.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7361782193183899}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02586038,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-021-00590-5', 'title': 'Ixazomib-based induction regimens plus ixazomib maintenance in transplant-ineligible, newly diagnosed multiple myeloma: the phase II, multi-arm, randomized UNITO-EMN10 trial', 'source': 'Nature', 'date': 'Dec 7, 2021', 'snippet': 'Here we present the results of the UNITO-EMN10 trial assessing four \nixazomib-based induction regimens followed by ixazomib maintenance in \nelderly, transplant-...', 'thumbnail': 'https://serpapi.com/searches/67241c9c910986cafe52bb15/images/8b24439da860dcfa98ba6a6ef616b82d9c5d706325a58117b4501d0f5063d001.png', 'sentiment': 'neutral', 'sentiment_prob': 0.917239248752594}",,,,,,,,,,['neutral'],neutral,1 NCT02417064,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/response-to-esketamine-after-initial-nonresponse/', 'title': 'Treatment Response With Esketamine Nasal Spray Plus an Oral 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Institutes of Health (NIH) (.gov)', 'date': 'Jun 28, 2022', 'snippet': 'A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating \nhealthy adult volunteers at the National Institutes of Health Clinical \nCenter in...', 'thumbnail': 'https://serpapi.com/searches/67241fb3910986cafe52bc6c/images/30ac80eb2182188796552b86489d32ea69cc60b6f3628a130d340b8807f58d49.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9052539467811584}",,,,,,,,,,['neutral'],neutral,1 NCT04070326,"{'position': 1, 'link': 'https://www.pharmaceutical-technology.com/news/takeda-wins-eu-approval-for-paediatric-use-of-takhzyro-in-hae/', 'title': 'Takeda wins EU approval for paediatric use of Takhzyro in HAE', 'source': 'Pharmaceutical Technology', 'date': 'Nov 20, 2023', 'snippet': 'Takhzyro has been approved for the routine prevention of recurrent \nhereditary angioedema attacks in patients aged two years and older.', 'thumbnail': 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'source': 'The New England Journal of Medicine', 'date': 'Sep 18, 2016', 'snippet': 'Romosozumab, a monoclonal antibody that binds sclerostin, increases bone \nformation and decreases bone resorption.', 'thumbnail': 'https://serpapi.com/searches/67241ff83c9575b4b1b6c54b/images/7976cee1d81bc700341d7d02de98a299213a9e4133810e925d89a99b195222ce.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8609321117401123}","{'position': 2, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/EVENITY-Romosozumab', 'title': 'Romosozumab (EVENITY®)', 'source': 'UCB', 'date': 'Aug 1, 2024', 'snippet': 'Osteoporosis, A study to learn how romosozumab worked in women with \nosteoporosis who had gone through menopause, Phase 3, 20070337', 'thumbnail': 'https://serpapi.com/searches/67241ff83c9575b4b1b6c54b/images/7976cee1d81bc7001757c0b2b313e2e9dacd6f21854f241c8116dffb5f76155b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8978717923164368}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01921712,"{'position': 1, 'link': 'https://copdnewstoday.com/news/copd-clinical-trial-shows-pur0200-good-as-spiriva-handihaler/', 'title': 'Phase 1 Trial Shows PUR0200 for COPD as Good as Spiriva HandiHaler', 'source': 'COPD News Today', 'date': 'Jun 19, 2018', 'snippet': 'PUR0200 was shown to promote similar improvements in lung function in \npatients with chronic obstructive pulmonary disease (COPD), but at \nsignificantly lower...', 'thumbnail': 'https://serpapi.com/searches/672420244e9efc855e4bd551/images/d59738989ae703ea27b4e406cdf19b1b2dfd1f703a3c2eb9ece281c72683cb09.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5749086141586304}",,,,,,,,,,['positive'],positive,1 NCT03541174,"{'position': 1, 'link': 'https://www.pharmaceutical-technology.com/news/fda-approves-idorsias-once-daily-antihypertensive-tryvio/', 'title': 'FDA approves Idorsia’s once-daily antihypertensive Tryvio', 'source': 'Pharmaceutical Technology', 'date': 'Mar 20, 2024', 'snippet': 'Switzerland-based Idorsia has received approval from the US Food and Drug \nAdministration (FDA) for the use of Tryvio (aprocitentan) as a combination \ntreatment...', 'thumbnail': 'https://serpapi.com/searches/672420261a5b544a73491ff6/images/af5999a6099b640d742f7d1e1e12c7778021ac3a7ac2f705acdb86daca1363f2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.689048707485199}",,,,,,,,,,['neutral'],neutral,1 NCT05630833,"{'position': 1, 'link': 'https://www.nature.com/articles/s41429-023-00629-8', 'title': 'Antibiotics in the clinical pipeline as of December 2022 - The Journal of Antibiotics', 'source': 'Nature', 'date': 'Jun 8, 2023', 'snippet': 'The need for new antibacterial drugs to treat the increasing global \nprevalence of drug-resistant bacterial infections has clearly attracted...', 'thumbnail': 'https://serpapi.com/searches/67241deb5809e75d7c4f6ff9/images/6ffc981a3a7a243f321156744847b22accbf4af91f76253328f990f4f299438c.png', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'New HEALEY ALS trial analyses showed a significant long-term survival \nbenefit for ALS patients treated with CNM-Au8 for up to 2.5 years.', 'thumbnail': 'https://serpapi.com/searches/67241f899fd3095eab7ea103/images/339d934d1f9e216e5be86d517357ebed3ab175d84db8a8840a8b3643eed9ca76.png', 'sentiment': 'positive', 'sentiment_prob': 0.6370849609375}","{'position': 2, 'link': 'https://alsnewstoday.com/news/cnm-au8-seen-to-extend-survival-by-more-than-1-5-years-in-als-trial/', 'title': 'CNM-Au8 seen to extend survival by more than 1.5 years in ALS trial', 'source': 'ALS News Today', 'date': 'Aug 31, 2023', 'snippet': 'CNM-Au8 was associated with prolonged survival and delayed disease \nprogression among ALS patients in the RESCUE-ALS clinical trial.', 'thumbnail': 'https://serpapi.com/searches/67241f899fd3095eab7ea103/images/339d934d1f9e216e60c7e76bcdd2ec355e24519918aba3d70b0939629346c8a7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.815616250038147}","{'position': 3, 'link': 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NCT03958656,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-43416-7', 'title': 'Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma', 'source': 'Nature', 'date': 'Nov 18, 2023', 'snippet': 'Chimeric Antigen Receptor (CAR) T cells directed to B cell maturation \nantigen (BCMA) mediate profound responses in patients with multiple...', 'thumbnail': 'https://serpapi.com/searches/67241e74d16915235705289a/images/3016fcb47d42eac415947bcc352afe06c0716a482ac6d038c31907b50024a344.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8046839237213135}","{'position': 2, 'link': 'https://www.nature.com/articles/s41408-021-00469-5', 'title': 'CAR T-cell therapy in multiple myeloma: more room for improvement - Blood Cancer Journal', 'source': 'Nature', 'date': 'Apr 29, 2021', 'snippet': 'The emergence of various novel therapies over the last decade has changed \nthe therapeutic landscape for multiple myeloma. While the clinical...', 'thumbnail': 'https://serpapi.com/searches/67241e74d16915235705289a/images/3016fcb47d42eac42246a5154a24d49564fd65634c793ade3e2981714516f5c6.png', 'sentiment': 'positive', 'sentiment_prob': 0.5632189512252808}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT00964340,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-55923-8', 'title': 'Emerging roles of SIRT1 activator, SRT2104, in disease treatment', 'source': 'Nature', 'date': 'Mar 6, 2024', 'snippet': 'Silent information regulator 1 (SIRT1) is a NAD+-dependent class III \ndeacetylase that plays important roles in the pathogenesis of numerous...', 'thumbnail': 'https://serpapi.com/searches/67241e7c1ec32ff94367ba24/images/f24cd9c295d235f25f1c28d2f83fd8ce8f864c382dc32e114790b648e798f4d0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8164551258087158}",,,,,,,,,,['neutral'],neutral,1 NCT02492789,"{'position': 1, 'link': 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19, 2022', 'snippet': 'In this study, narsoplimab treatment was safe, significantly improved \nlaboratory TMA markers, and resulted in clinical response and favorable \noverall survival.', 'thumbnail': 'https://serpapi.com/searches/67241e842da983780b740fb8/images/2df20b4aa1e861e1e69f531b35c85b9111f72d6c09200a634f0fd65c6648997f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7991372346878052}",,,,,,,,,,['neutral'],neutral,1 NCT03954743,"{'position': 1, 'link': 'https://www.empr.com/home/news/new-formulation-of-rotarix-removes-the-need-for-reconstitution/', 'title': 'New Formulation of Rotarix Removes the Need for Reconstitution', 'source': 'Medical Professionals Reference', 'date': 'Nov 9, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved an oral-dosing \napplicator-only presentation (liquid formulation) of Rotarix (rotavirus...', 'thumbnail': 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We \nperformed this phase 3 trial to confirm a previous study in which...', 'thumbnail': 'https://serpapi.com/searches/67241e98cc48795386827a54/images/a5ee9a00e5719fb1aea5e8492785b0bf5fb841edbcb6aab7752c258038bcf7d6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5381135940551758}",,,,,,,,,,['neutral'],neutral,1 NCT01882439,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1615977', 'title': 'Tofacitinib for Psoriatic Arthritis in Patients with an Inadequate Response to TNF Inhibitors', 'source': 'The New England Journal of Medicine', 'date': 'Oct 19, 2017', 'snippet': 'Tofacitinib is an oral Janus kinase inhibitor that is under investigation \nfor the treatment of psoriatic arthritis. 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Circulating tumor DNA \nfraction...', 'thumbnail': 'https://serpapi.com/searches/67241ef3f41044183f19b64f/images/ac65785d933bd44097030d360426b3ed8af71b8495094c7f2064727b8e52e49b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5421239137649536}","{'position': 2, 'link': 'https://prostatecancernewstoday.com/2019/01/27/xtandi-should-follow-zytiga-for-castration-resistant-prostate-cancer-phase-2-trial/', 'title': 'CRPC Patients Should Take Xtandi After Zytiga, Phase 2 Trial Shows', 'source': 'prostatecancernewstoday.com', 'date': 'Jan 27, 2019', 'snippet': 'The trial showed that when deciding first- and second-line treatment for \nmen with advanced prostate cancers, Zytiga should be offered first.', 'thumbnail': 'https://serpapi.com/searches/67241ef3f41044183f19b64f/images/ac65785d933bd440ed3abb7d088764ce96877be641e991afee78b32186ed1c96.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8925011157989502}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02991482,"{'position': 1, 'link': 'https://www.asbestos.com/treatment/immunotherapy/keytruda/', 'title': 'Keytruda for Mesothelioma: FDA-Approved Immunotherapy Drug', 'source': 'Mesothelioma Center', 'date': 'Jul 21, 2017', 'snippet': 'Pembrolizumab (Keytruda) is an FDA-approved second-line mesothelioma \ntreatment. 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'thumbnail': 'https://serpapi.com/searches/672421126aa364780f49d58a/images/871893de37d16d4b99e41177e9aa308ab1c386c9567f7d7058fc8ce85958f040.png', 'sentiment': 'positive', 'sentiment_prob': 0.5697094202041626}",,,,,,,,,,['positive'],positive,1 NCT05018806,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/sanofi-gears-up-for-approval-of-its-btk-inhibitor-meets-phase-iii-endpoint/', 'title': 'Sanofi gears up for approval of its BTK inhibitor, meets Phase III endpoint', 'source': 'Clinical Trials Arena', 'date': 'Apr 23, 2024', 'snippet': ""Sanofi's rilzabrutinib met the primary endpoint in the Phase III persistent \nor chronic immune thrombocytopenia trial."", 'thumbnail': 'https://serpapi.com/searches/67242143bb64ac868baba67c/images/6401338221eede70e5fbc84c838e372b26de57a848fcd7d327310e3df9b3bbdf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6001195311546326}",,,,,,,,,,['neutral'],neutral,1 NCT02638207,"{'position': 1, 'link': 'https://www.empr.com/home/news/panzyga-immune-globulin-ifas-approved-chronic-inflammatory-demyelinating-polynueuropathy/', 'title': 'Panzyga Approved for Chronic Inflammatory Demyelinating Polyneuropathy', 'source': 'Medical Professionals Reference', 'date': 'Feb 16, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Panzyga (immune \nglobulin intravenous [human] – ifas 10% liquid preparation; Pfizer) for the \ntreatment of...', 'thumbnail': 'https://serpapi.com/searches/6724215014c31ed5c411cfdc/images/215f4f18e4d762dada617a8ef2b54d07af84ead39c8572a643acfe261087bb81.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8948565125465393}",,,,,,,,,,['neutral'],neutral,1 NCT02720263,"{'position': 1, 'link': 'https://www.nature.com/articles/s41386-020-00908-0', 'title': 'Phase 1 randomized study on the safety, tolerability, and pharmacodynamic cognitive and electrophysiological effects of a dopamine D1 receptor positive allosteric modulator in patients with schizophrenia | Neuropsychopharmacology', 'source': 'Nature', 'date': 'Nov 17, 2020', 'snippet': 'ASP4345, a novel dopamine D1 receptor positive allosteric modulator, is \nbeing evaluated for the treatment of cognitive impairment associated...', 'thumbnail': 'https://serpapi.com/searches/6724215b7c171214322e9ef7/images/2420c200c8701efb7bf435dda052058a07690bbbdbd7df102803c547592d8604.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9120137095451355}",,,,,,,,,,['neutral'],neutral,1 NCT03805347,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0378874122004743', 'title': 'Effect of the traditional Chinese herb Helminthostachys zeylanica on postsurgical recovery in patients with ankle fracture: A double-blinded randomized controlled clinical trial', 'source': 'ScienceDirect.com', 'date': 'Sep 15, 2022', 'snippet': 'Oral administration of HZ for 42 days can increase serum PINP level and \nreduce the RHT. Therefore, HZ can be used to treat patients with ankle \nfractures...', 'thumbnail': 'https://serpapi.com/searches/67242185f60b6f8ef9bdaaea/images/85284354a2a6eb10f7d2587a4d0309e46dd8f1d96d115c7ace856eb5f4be180d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.738072395324707}",,,,,,,,,,['neutral'],neutral,1 NCT02257567,"{'position': 1, 'link': 'https://lymphomanewstoday.com/2020/01/23/polivy-triple-combo-approved-in-europe-for-select-patients-with-advanced-dlbcl/', 'title': 'Polivy Triple Combo Approved in Europe for Select Patients with Advanced DLBCL', 'source': 'Lymphoma News Today', 'date': 'Jan 23, 2020', 'snippet': ""Conditional approval was given to Roche's Polivy, used with rituximab and \nbendamustine, to treat relapsed or refractory DLBCL patients..."", 'thumbnail': 'https://serpapi.com/searches/672421dcfc183d5decdfb7b2/images/5b64a8c98b1f0f0ace91fb5611be296840f0645aac932957c38cbccd9e74debd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8473636507987976}","{'position': 2, 'link': 'https://lymphomanewstoday.com/2019/11/22/chmp-favors-eu-approval-of-polivy-with-rituxan-and-bendamustine-for-advanced-dlbcl/', 'title': 'EU Advisory Committee Favors Approval of Polivy with MabThera and Bendamustine for Advanced DLBCL', 'source': 'Lymphoma News Today', 'date': 'Nov 22, 2019', 'snippet': ""The European Medicines Agency's advisory committee has recommended the \napproval of Polivy with Rituxan and bendamustine for the treatment of..."", 'thumbnail': 'https://serpapi.com/searches/672421dcfc183d5decdfb7b2/images/5b64a8c98b1f0f0a02a20e7b96be87f9e168c4c29d1ba60cbfbcbaa8f85dfd2f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8113265037536621}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02842827,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01341-7', 'title': 'Targeting epigenetic regulators to overcome drug resistance in cancers', 'source': 'Nature', 'date': 'Feb 17, 2023', 'snippet': 'Drug resistance is mainly responsible for cancer recurrence and poor \nprognosis. Epigenetic regulation is a heritable change in gene...', 'thumbnail': 'https://serpapi.com/searches/672421e10c08f201ce46e13d/images/99c6f8658a40c45eab2e8098aad2ec39b76180049b6290e0ecbce17fdcf3d216.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6539433002471924}",,,,,,,,,,['negative'],negative,0 NCT03625466,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/preschool-aged-childrens-cf-lung-damage-reduced-orkambi/', 'title': ""Preschool-aged children's CF lung damage reduced by Orkambi |..."", 'source': 'Cystic Fibrosis News Today', 'date': 'Apr 3, 2023', 'snippet': 'The main purpose of the small Phase 2 clinical trial was to see how \ntreatment with Orkambi (lumacaftor/ivacaftor) affects MRI global scores.', 'thumbnail': 'https://serpapi.com/searches/67242217cdf155b9fbb89f34/images/eedc34e654abd089446420b4bbba0ae9a38eb4caebcd751d014240e9f4e8d559.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8653139472007751}",,,,,,,,,,['neutral'],neutral,1 NCT05249829,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-30878-4', 'title': 'Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2', 'source': 'Nature', 'date': 'Jun 6, 2022', 'snippet': 'We generate an Omicron-specific lipid nanoparticle (LNP) mRNA vaccine \ncandidate, and test its activity in animals, both alone and as a \nheterologous booster to...', 'thumbnail': 'https://serpapi.com/searches/67242220361fd42d28a88cc5/images/90656de2b01257f244920df5c41a1d01881f7e4f5043053b64f11cb84d7880e1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9088650345802307}",,,,,,,,,,['neutral'],neutral,1 NCT03564821,"{'position': 1, 'link': 'https://www.researchgate.net/figure/History-of-AML-therapies-Timeline-of-approved-clinical-therapies-in-the-United-States_fig1_347673267', 'title': 'Fig. 1 History of AML therapies. Timeline of approved clinical...', 'source': 'ResearchGate', 'date': 'May 8, 2022', 'snippet': 'For many years, treatment options for AML remained stagnant, with the \nstandard 7+3 regimen of cytarabine and daunorubicin and SCT being the only \noption for...', 'thumbnail': 'https://serpapi.com/searches/672422231315022822549dce/images/a86c5d18cecf3575a89e36bbe7e1311ff4dd0bd64a32a0a1fa0579894146caea.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5696207880973816}",,,,,,,,,,['neutral'],neutral,1 NCT01216644,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30531-9/fulltext', 'title': 'Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): res', 'source': 'The Lancet', 'date': 'Oct 21, 2016', 'snippet': 'Prospective, randomized, multicenter, phase III study of fluorouracil, \nleucovorin, and irinotecan versus epirubicin, cisplatin, and capecitabine \nin advanced...', 'thumbnail': 'https://serpapi.com/searches/67242252e10f0ad85e5e2f6a/images/ae9045f27fb2eac9a25068cbc0fa16ea3509bed1c6e5ccc0ca6088b0282a5e78.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8513209223747253}",,,,,,,,,,['neutral'],neutral,1 NCT00094718,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMp2301816', 'title': 'Combating West Nile Virus Disease — Time to Revisit Vaccination', 'source': 'The New England Journal of Medicine', 'date': 'Apr 29, 2023', 'snippet': 'WNV remains a public health threat in many areas of the world, and current \napproaches to primary prevention have limitations.', 'thumbnail': 'https://serpapi.com/searches/67242256861b9d63abef912f/images/9eabf85bd9e81ab1a430701fc41cbe59063816cf56c34bd48a6d61fc644dffb9.png', 'sentiment': 'negative', 'sentiment_prob': 0.7227003574371338}",,,,,,,,,,['negative'],negative,0 NCT01491893,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1716435', 'title': 'Recurrent Glioblastoma Treated with Recombinant Poliovirus', 'source': 'The New England Journal of Medicine', 'date': 'Jun 28, 2018', 'snippet': 'The prognosis of patients with recurrent World Health Organization (WHO) \ngrade IV malignant glioma is dismal, and there is currently no...', 'thumbnail': 'https://serpapi.com/searches/6724226008abe42058644933/images/254614f9da9eb8b511e18abf895c1935388e674224b86f3f7b7c1c40cabe8de8.png', 'sentiment': 'negative', 'sentiment_prob': 0.8526854515075684}",,,,,,,,,,['negative'],negative,0 NCT00605514,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-024-00833-z', 'title': 'Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials', 'source': 'Nature', 'date': 'Mar 29, 2024', 'snippet': 'Ebola virus disease (EVD) is a filoviral infection caused by virus species \nof the Ebolavirus genus including Zaire ebolavirus (EBOV) and...', 'thumbnail': 'https://serpapi.com/searches/67242677b6e4db2835633206/images/d87e79f0d7a15079dbf425477eca788d0db7cf0024151723804f25fa23a8859f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.788805365562439}",,,,,,,,,,['neutral'],neutral,1 NCT02626130,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-021-26415-4', 'title': 'Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma', 'source': 'Nature', 'date': 'Nov 4, 2021', 'snippet': 'Cryoablation in combination with immune checkpoint therapy was previously \nreported to improve anti-tumor immune responses in pre-clinical...', 'thumbnail': 'https://serpapi.com/searches/6724269d360f4e3ba57d84ee/images/49629e27e5e7a65c2620743388b3d2f345b36d4a6be607a74e6f6971d3525a8b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8851354122161865}",,,,,,,,,,['neutral'],neutral,1 NCT03125902,"{'position': 1, 'link': 'https://www.empr.com/home/news/tecentriq-indication-for-triple-negative-breast-cancer-withdrawn/', 'title': 'Tecentriq Indication for Triple-Negative Breast Cancer Withdrawn', 'source': 'Medical Professionals Reference', 'date': 'Aug 30, 2021', 'snippet': 'Roche is voluntarily withdrawing the indication for Tecentriq \n(atezolizumab) in combination with chemotherapy (Abraxane, paclitaxel bound \nto albumin [human];...', 'thumbnail': 'https://serpapi.com/searches/672426a83ad34db6ba165597/images/23ce9b4961d5f5c199039efbab47bad4f47e4967e73af1439b4c129f70166e83.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6629008054733276}",,,,,,,,,,['neutral'],neutral,1 NCT04765449,"{'position': 1, 'link': 'https://www.cgtlive.com/view/second-cohort-dosed-in-covid-19-cell-therapy-trial', 'title': 'COVID-19 Cell Therapy Trial Completes Dosing', 'source': 'CGTLive®', 'date': 'Feb 3, 2022', 'snippet': 'The second, higher-dose cohort has finished dosing in the phase 1 study \n(NCT04765449) of TVGN-489, an investigational allogeneic SARS-CoV-2 \nspecific CD8+ T-...', 'thumbnail': 'https://serpapi.com/searches/672426df9936882cebcb8791/images/1b718d5205588006abe27858d81fbcb8e46a90e9b90051940715f34d05776d4e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9122409224510193}",,,,,,,,,,['neutral'],neutral,1 NCT00997607,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-024-00833-z', 'title': 'Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials', 'source': 'Nature', 'date': 'Mar 29, 2024', 'snippet': 'Ebola virus disease (EVD) is a filoviral infection caused by virus species \nof the Ebolavirus genus including Zaire ebolavirus (EBOV) and...', 'thumbnail': 'https://serpapi.com/searches/672426e07ebde514439a8baf/images/b413708034ffcec82948f3f5f342f7d6f5779a46d53a5f0a618f21aeab463137.png', 'sentiment': 'neutral', 'sentiment_prob': 0.788805365562439}",,,,,,,,,,['neutral'],neutral,1 NCT00605215,"{'position': 1, 'link': 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Medicine', 'date': 'Sep 25, 2019', 'snippet': 'Ustekinumab was more effective than placebo for inducing and maintaining \nremission in patients with moderate-to-severe ulcerative colitis.', 'thumbnail': 'https://serpapi.com/searches/672425ae167793224537bf48/images/ed5523fd357568d20fae29a92b7e991a6b2cc8f8990cbe406247e5d9cb48c0e7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4859568178653717}","{'position': 2, 'link': 'https://ibdnewstoday.com/2020/06/01/nice-recommends-stelara-for-moderate-severe-ulcerative-colitis-uk/', 'title': 'Ulcerative Colitis Therapy Stelara Recommended for UK Approval by NICE', 'source': 'IBD News Today', 'date': 'Jun 1, 2020', 'snippet': 'The U.K. National Institute for Health and Care Excellence has recommended \nStelara to treat ulcerative colitis patients who do not respond...', 'thumbnail': 'https://serpapi.com/searches/672425ae167793224537bf48/images/ed5523fd357568d2ab61675bed80dc985750a1f580cb750a9ab118a39f8a133b.jpeg', 'sentiment': 'neutral', 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Kuo, Giuseppe Esposito, Gary A. Ulaner, Don Yoo, Katherine \nZukotynski, Gregory C. Ravizzini, Ross Penny, Matthew P. Miller,...', 'thumbnail': 'https://serpapi.com/searches/6724234c72e5c4d06f86cc81/images/5feb0a81aa28e7b514aca8a239b09753163b1ac49386913c0b2557bf95df128b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9256315231323242}","{'position': 3, 'link': 'https://www.biospace.com/news/results-of-posluma-flotufolastat-f-18-performance-in-recurrent-prostate-cancer-after-radical-prostatectomy-at-low-prostate-specific-antigen-psa-levels-presented-at-astro', 'title': 'Results of POSLUMA® (Flotufolastat F 18) Performance in Recurrent Prostate Cancer After Radical Prostatectomy at Low Prostate Specific Antigen (PSA) Levels Presented at ASTRO', 'source': 'BioSpace', 'date': '1 month ago', 'snippet': 'Results demonstrated 69% and 67% detection rates for POSLUMA in men with \nPSA < 1 ng/mL (82/119) and < 0.5 ng/mL (57/85), respectively.', 'thumbnail': 'https://serpapi.com/searches/6724234c72e5c4d06f86cc81/images/5feb0a81aa28e7b558b719f09fca1b16b6b1f1c11c06756a7bc3d1d71b001261.png', 'sentiment': 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alfa not only restores normal blood cell counts in patients with \npolycythemia vera (PV) but can diminish the mutant JAK2V617F...', 'thumbnail': 'https://serpapi.com/searches/6724238e18787da4074e8ce2/images/858147cd50eb8fd15155989795d0867e8d0b3234f7b89d103f93dddf0b0ea977.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7943735122680664}",,,,,,,,,,['neutral'],neutral,1 NCT03138733,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2300220', 'title': 'Ceftobiprole for Treatment of Complicated Staphylococcus aureus Bacteremia', 'source': 'The New England Journal of Medicine', 'date': 'Sep 27, 2023', 'snippet': 'Ceftobiprole is a cephalosporin that may be effective for treating \ncomplicated Staphylococcus aureus bacteremia, including \nmethicillin-resistant S. aureus.', 'thumbnail': 'https://serpapi.com/searches/6724246493584c2b3cbc033c/images/9e3e8a44b275ebdf3ed9d50dac6b9eddff1a7bf84cf8b4d71e7d213a0a523fbe.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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iron chelator deferiprone can reduce \nnigrostriatal iron content in persons with Parkinson's disease."", 'thumbnail': 'https://serpapi.com/searches/672423e8d19f1542acb32fa3/images/ebda5a0d4242151194634287fd08c82e6304e13579f3df0df1ad7ce55b668eec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8972376585006714}",,,,,,,,,,['neutral'],neutral,1 NCT02836873,"{'position': 1, 'link': 'https://www.empr.com/home/news/brenzavvy-approved-for-adults-with-type-2-diabetes/', 'title': 'Brenzavvy Approved for Adults With Type 2 Diabetes', 'source': 'Medical Professionals Reference', 'date': 'Jan 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Brenzavvy™ \n(bexagliflozin) as an adjunct to diet and exercise to improve glycemic...', 'thumbnail': 'https://serpapi.com/searches/672423eab2ebaee6e82f445b/images/cd16a24be4869345bd6945f79ec5e68e924423f4e45a81f6ba042315300b742f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6072625517845154}",,,,,,,,,,['neutral'],neutral,1 NCT05516316,"{'position': 1, 'link': 'https://copdnewstoday.com/news/fda-oks-phase-2-clinical-trial-ep395-copd-patients/', 'title': 'FDA OKs Phase 2 Clinical Trial of EP395 for COPD Patients', 'source': 'COPD News Today', 'date': 'Nov 28, 2022', 'snippet': 'The US Food and Drug Administration (FDA) has authorized EpiEndo \nPharmaceuticals to conduct a Phase 2a clinical trial of its antibiotic \ntreatment EP395 in...', 'thumbnail': 'https://serpapi.com/searches/672423f481bab7b8fdf0d98c/images/2ed3313bc6b677791175a5a59c778955526b2cf19f1b87a791ae5894d02f4a8a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8805156350135803}",,,,,,,,,,['neutral'],neutral,1 NCT01094158,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-022-01119-3', 'title': 'Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)', 'source': 'Nature', 'date': 'Aug 13, 2022', 'snippet': 'In this review, we discussed recent developments in etiology 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neutralizing antibodies protect monkeys from HIV-like virus', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Apr 16, 2018', 'snippet': 'NIH scientists report single dose elicited long-term protection.', 'thumbnail': 'https://serpapi.com/searches/6724245c2a7727e9d24446e9/images/c2184a39fa69b9aa043b956d68015b5d1ae7c32a81108dcbe1c503bfbc5c04e9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6590275168418884}",,,,,,,,,,['neutral'],neutral,1 NCT01854918,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1500858', 'title': 'Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events', 'source': 'The New England Journal of Medicine', 'date': 'Mar 15, 2015', 'snippet': 'Evolocumab, a monoclonal antibody that inhibits proprotein convertase \nsubtilisin–kexin type 9 (PCSK9), significantly reduced low-density...', 'thumbnail': 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with Dysglycemia', 'source': 'The New England Journal of Medicine', 'date': 'Feb 27, 2017', 'snippet': 'The use of n–3 fatty acids may prevent cardiovascular events in patients \nwith recent myocardial infarction or heart failure. Their effects in \npatients with...', 'thumbnail': 'https://serpapi.com/searches/672424fbb5ecbb920ddedfd1/images/f5779ce914ebdf6399ec4a1f2bf12372d90f5ae06115fd890ea7f004fac0688a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.705805242061615}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03525548,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/benefits-trikafta-cf-sustained-3-5-years-extension-trial/', 'title': 'Benefits of Trikafta for CF sustained 3.5+ years in extension trial', 'source': 'Cystic Fibrosis News Today', 'date': 'Jun 14, 2023', 'snippet': 'Long-term treatment with Trikafta leads to sustained lung function gains, \neasing of respiratory symptoms, and better nutritional status.', 'thumbnail': 'https://serpapi.com/searches/6724252ae9b691746b5d2192/images/504aa91550b00834b6f3a66be4ec3cc175bcc847c113a7f44615ad838a5e69fc.png', 'sentiment': 'positive', 'sentiment_prob': 0.8928873538970947}","{'position': 2, 'link': 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N-methyl-D-aspartate (NMDA) receptor antagonist ketamine \ndisplays rapid antidepressant effects in patients with...', 'thumbnail': 'https://serpapi.com/searches/67242533d9c3e6887205f3a2/images/a1e4831e7bc18d1d71e4aa62082f3d4da6039541e2e74395e71fe9bc653b04d4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8738411664962769}","{'position': 2, 'link': 'https://www.psychiatrictimes.com/view/ketamine-induced-optimism-new-hope-development-rapid-acting-antidepressants', 'title': 'Ketamine-Induced Optimism: New Hope for the Development of Rapid-Acting Antidepressants', 'source': 'Psychiatric Times', 'date': 'Jul 13, 2012', 'snippet': 'There is rapidly escalating interest in drugs that target the glutamatergic \nneurotransmitter system, especially NMDA receptor modulators.', 'thumbnail': 'https://serpapi.com/searches/67242533d9c3e6887205f3a2/images/a1e4831e7bc18d1d1e7744b6b1d9b75fb45be6aeeaebb01cffadb9295aa15138.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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'snippet': 'In this review, we summarize and discuss the latest developments in \nnanoparticles (NPs) for cancer immuno-oncology therapy with a focus on \nlipid-based NPs (...', 'thumbnail': 'https://serpapi.com/searches/6724279708abe42058644a7b/images/a889c28568966c8cfdbb3f37ca1e25a9b3bf74645879f583d6e2244982defd80.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9235424399375916}",,,,,,,,,,['neutral'],neutral,1 NCT02407990,"{'position': 1, 'link': 'https://immuno-oncologynews.com/2016/07/26/beigene-presents-initial-clinical-data-showing-anti-cancer-activity-in-range-of-solid-tumors/', 'title': ""Immunotherapy Trial's Early Results Show Activity in Solid Tumors"", 'source': 'Immuno-Oncology News', 'date': 'Jul 26, 2016', 'snippet': 'Preliminary study results revealed that BGB-A317 was well-tolerated and \ndisplayed anti-tumor activity in a number of solid tumors.', 'thumbnail': 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adults with moderately to severely active Crohn \ndisease.', 'thumbnail': 'https://serpapi.com/searches/672427f552a04ebc00472a4a/images/379655d1eb11a3f0b50b681b505aeebae33ed40f33d3fcff69102938b651f1f5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8569288849830627}","{'position': 2, 'link': 'https://www.pharmacypracticenews.com/FDA-News/GI-Disorders/Article/05-23/FDA-Grants-New-Indication-for-Rinvoq%E2%80%94Once-Daily-Pill-for-Crohns-Disease/70347', 'title': 'FDA Grants New Indication for Rinvoq—Once-Daily Pill for Crohn’s Disease', 'source': 'Pharmacy Practice News', 'date': 'May 19, 2023', 'snippet': ""The FDA granted a new indication for Rinvoq to treat adults with moderate \nto severe active Crohn's disease who have not responded adequately..."", 'thumbnail': 'https://serpapi.com/searches/672427f552a04ebc00472a4a/images/379655d1eb11a3f00db937261469e3131a0c96bc0d3855515eb42c07e635416a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8453056812286377}",,,,,,,,,"['neutral', 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'snippet': ""Find more about the new Repros Therapeutics's patent on the therapeutic use \nof Proellex for treatment of endometriosis and uterine fibrosis."", 'thumbnail': 'https://serpapi.com/searches/6724282afcd69e09522383d6/images/6ee8a03066d55702a2e59208b6619a64a8549ee47e55614ef9adea4157a19086.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7862261533737183}",,,,,,,,,,['neutral'],neutral,1 NCT04349241,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-85227-0', 'title': 'RETRACTED ARTICLE: Safety and efficacy of favipiravir versus hydroxychloroquine in management of COVID-19: A randomised controlled trial', 'source': 'Nature', 'date': 'Mar 31, 2021', 'snippet': 'Favipiravir is considered a potential treatment for COVID-19 due its \nefficacy against different viral infections.', 'thumbnail': 'https://serpapi.com/searches/672428a13c863da09593e423/images/3cb64b2401c4e2a08f1c3822b09c6e4b61dcf96f9fb47488890624ec658793d3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8897945284843445}","{'position': 2, 'link': 'https://retractionwatch.com/2021/09/22/study-comparing-hydroxychloroquine-and-antiviral-drug-for-covid-19-retracted/', 'title': 'Study comparing hydroxychloroquine and antiviral drug for COVID-19 retracted', 'source': 'Retraction Watch', 'date': 'Sep 22, 2021', 'snippet': 'The authors of a study comparing hydroxychloroquine and the antiviral agent \nfavipiravir as treatments for COVID-19 have lost the paper after...', 'thumbnail': 'https://serpapi.com/searches/672428a13c863da09593e423/images/3cb64b2401c4e2a0b9be4d20abb82bb16c4d7a51d4f89b1191b0066e857ca19a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5473102331161499}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT03520946,"{'position': 1, 'link': 'https://www.onclive.com/view/ramucirumab-plus-tas-102-fails-to-improve-os-in-heavily-pretreated-mcrc', 'title': 'Ramucirumab Plus TAS-102 Fails to Improve OS in Heavily Pretreated mCRC', 'source': 'OncLive', 'date': '1 month ago', 'snippet': 'Ramucirumab plus trifluridine/tipiracil failed to improve overall survival \nvs TAS-102 alone in patients with heavily pretreated metastatic...', 'thumbnail': 'https://serpapi.com/searches/672428a9b57db8f4c1c6344d/images/b8bfc8b98fffe774b7387f66286cf016325fa89facaab659a911e159fe186145.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.8171577453613281}",,,,,,,,,,['negative'],negative,0 NCT00074971,"{'position': 1, 'link': 'https://fabrydiseasenews.com/fabrazyme-is-first-fabry-disease-therapy/', 'title': 'Fabrazyme (agalsidase beta) for Fabry disease', 'source': 'Fabry Disease News', 'date': 'Mar 4, 2024', 'snippet': 'Fabrazyme is an enzyme replacement therapy and the first treatment that \nscientists developed specifically for Fabry disease.', 'thumbnail': 'https://serpapi.com/searches/672428c47ca6b3ab0d2b4fac/images/3ca6f9c22d71ac237b5c1584ff908002a94999c3801c3419723e6a89e96fbd21.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': 'Abstract Background Bevacizumab has been studied in numerous clinical \ntrials in multiple types of cancer; however, patients may receive...', 'thumbnail': 'https://serpapi.com/searches/672428d717b10eb87f4914dc/images/3bb5121066f12fdadfd320e32b1f292cf1d4a3ba8a75cfa7e04cee6fc6bef6a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9322308897972107}",,,,,,,,,,['neutral'],neutral,1 NCT02716038,"{'position': 1, 'link': 'https://www.onclive.com/view/dr-henick-on-the-use-of-neoadjuvant-atezolizumab-plus-chemotherapy-in-nsclc', 'title': 'Dr Henick on the Use of Neoadjuvant Atezolizumab Plus Chemotherapy in NSCLC', 'source': 'OncLive', 'date': 'May 16, 2023', 'snippet': 'Brian Henick, MD, associate director, Experimental Therapeutics, director, \nTranslational Research in Aerodigestive Cancers in Medical...', 'thumbnail': 'https://serpapi.com/searches/672428f1e50bc00593807b3f/images/ae9feef2ebe0f946fc3fe9f6e6498a67d1cd976ef2a626a1d6c470e80551c2bf.jpeg', 'sentiment': 'neutral', 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'source': 'Frontiers', 'date': 'Oct 19, 2023', 'snippet': 'In this review, we outline the current progress and latest updates on \nmicrobial therapeutics, with particular emphasis on gut commensal \nengineering driven by...', 'thumbnail': 'https://serpapi.com/searches/67242a7d360f4e3ba57d85e4/images/fc5b9df3324bee92b6f8c21b02e9229e696d36e3aa7e19cc9cb5d92e4eb9f56c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9050130844116211}",,,,,,,,,,['neutral'],neutral,1 NCT03006276,"{'position': 1, 'link': 'https://www.neurologyadvisor.com/news/celecoxib-effective-migraine-pain-relief-symptoms-aura-status-ahs-2022/', 'title': 'Celecoxib Effective for Migraine Pain Relief, Symptoms Regardless of Aura Status', 'source': 'Neurology Advisor', 'date': 'Jun 15, 2022', 'snippet': 'Oral celecoxib is more effective than placebo for the treatment of acute \nmigraine with or without aura, according to a pooled analysis of data from \n2 clinical...', 'thumbnail': 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'snippet': 'We have a variety of ongoing clinical trials in different therapeutic \nareas, which are detailed below.', 'thumbnail': 'https://serpapi.com/searches/67242ab874f0a4921704f810/images/8a1f9ee0e3afbacf8583115df2a614af2d8d4cecbf5c6cd92b75ab04c988f50a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8589240908622742}",,,,,,,,,,['neutral'],neutral,1 NCT04849429,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.992476/full', 'title': 'Exosomes and exosomal miRNAs: A new therapy for intervertebral disc degeneration', 'source': 'Frontiers', 'date': 'Sep 8, 2022', 'snippet': 'The aim of this paper is to identify the latest research results, potential \napplications and challenges of this emerging treatment strategy.', 'thumbnail': 'https://serpapi.com/searches/672429482bab905d51ccb89d/images/495ee0f75d905071504da24545e77d840d2579c421fa5b4f5f0d209b39842d02.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8698508143424988}",,,,,,,,,,['neutral'],neutral,1 NCT02926833,"{'position': 1, 'link': 'https://lymphomahub.com/medical-information/primary-analysis-of-phase-iii-of-the-zuma-6-trial-axicabtagene-ciloleucel-plus-atezolizumab-for-patients-with-refractory-dlbcl', 'title': 'Primary analysis of phase I/II of the ZUMA-6 trial – axicabtagene ciloleucel plus atezolizumab for patients with refractory DLBCL', 'source': 'Lymphoma Hub', 'date': 'Jun 5, 2020', 'snippet': 'The phase I/II of the ZUMA-6 (NCT02926833) study is currently investigating \nthe safety and efficacy of axi-cel in combination with the...', 'thumbnail': 'https://serpapi.com/searches/6724296f7a12fd607b597824/images/3a216ef0ed74a999824e093a850eeaff84fa36330e15c03c00051bf9fdcb3e81.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9170985817909241}",,,,,,,,,,['neutral'],neutral,1 NCT04662281,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/postherpetic-neuralgia-market-to-accelerate-significantly-at-a-cagr-of-14-by-2034--delveinsight-302168037.html', 'title': 'Postherpetic Neuralgia Market to Accelerate Significantly at a CAGR of 14% by 2034 | DelveInsight', 'source': 'PR Newswire', 'date': 'Jun 10, 2024', 'snippet': 'The postherpetic neuralgia market is expected to show positive growth, \nmainly attributed to increased incidence and the anticipated launch of \nnovel therapies.', 'thumbnail': 'https://serpapi.com/searches/6724298d3c9575b4e24eb4d4/images/85429a991056f6b9eb6ee1ffc56963d25130bc9b91151d7a86049653ca21963a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.8809778094291687}",,,,,,,,,,['positive'],positive,1 NCT01696396,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222015633', 'title': 'Breaking through the therapeutic ceiling of inflammatory bowel disease: Dual-targeted therapies', 'source': 'ScienceDirect.com', 'date': 'Dec 31, 2022', 'snippet': 'Emerging biologics and small molecule drugs are navigating the clinical \nlandscape of inflammatory bowel disease (IBD).', 'thumbnail': 'https://serpapi.com/searches/67242999cb33d04548491b7a/images/08647b64b6a01410dc351b8dbf67b3062e3d75d4848db7631c6af2b4e6639a8c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.830076277256012}",,,,,,,,,,['neutral'],neutral,1 NCT03474198,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2212537', 'title': 'Treatment Strategy for Rifampin-Susceptible Tuberculosis', 'source': 'The New England Journal of Medicine', 'date': 'Feb 20, 2023', 'snippet': 'In this adaptive, open-label, noninferiority trial, we randomly assigned \nparticipants with rifampin-susceptible pulmonary tuberculosis to undergo \neither...', 'thumbnail': 'https://serpapi.com/searches/6724299bce1e10a3d76f1d9e/images/4d05260030c563090bbf6accd9051f624b8487a5929bc414333f0aa071d68e1e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8868440389633179}",,,,,,,,,,['neutral'],neutral,1 NCT04103060,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.986918/full', 'title': 'Advances in vitiligo: Update on therapeutic targets', 'source': 'Frontiers', 'date': 'Aug 30, 2022', 'snippet': 'Vitiligo, whose treatment remains a serious concern and challenge, is an \nautoimmune skin disease characterized by patches of depigmentation.', 'thumbnail': 'https://serpapi.com/searches/672429bc75f97436c9f2c084/images/d761c99f244dc0a7af50ff2ff9d32817264ae05d187549c50801d21da4c4a636.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6913387775421143}",,,,,,,,,,['neutral'],neutral,1 NCT01889186,"{'position': 1, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00070-6/fulltext', 'title': 'Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial', 'source': 'The Lancet', 'date': 'Mar 8, 2024', 'snippet': 'Most patients with chronic lymphocytic leukaemia progress after treatment \nor retreatment with targeted therapy or chemoimmunotherapy and...', 'thumbnail': 'https://serpapi.com/searches/672429e41fc7c51f052f0fc0/images/39b010b783722fabd86c55d8ce3fad2140ff692a8e974dcf701d4201111eed31.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8870301842689514}","{'position': 2, 'link': 'https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30019-5/fulltext', 'title': 'Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study', 'source': 'The Lancet', 'date': 'May 10, 2016', 'snippet': 'Deletion of chromosome 17p (del[17p]) in patients with chronic lymphocytic \nleukaemia confers very poor prognosis when treated with standard...', 'thumbnail': 'https://serpapi.com/searches/672429e41fc7c51f052f0fc0/images/39b010b783722faba67a3b92c070545a43ff6cf67e122747287f181ef9713e4d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6274240016937256}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02260791,"{'position': 1, 'link': 'https://juvenilearthritisnews.com/2020/07/10/hulio-biosimilar-of-humira-wins-fda-approval-jia-but-not-available-until-2023/', 'title': 'Hulio Use for JIA Approved by FDA, Biosimilar of Humira', 'source': 'Juvenile Arthritis News', 'date': 'Jul 10, 2020', 'snippet': 'The US Food and Drug Administration (FDA) has approved Hulio, a biosimilar \nof Humira (adalimumab), for the treatment of juvenile idiopathic arthritis \n(JIA) in...', 'thumbnail': 'https://serpapi.com/searches/67242acd03775653ac4ab52a/images/7a47396e5c40cb87538e0ccb9a8e92b9ffcd8508a6181be382904478c7591089.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.773018479347229}",,,,,,,,,,['neutral'],neutral,1 NCT02041533,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1613493', 'title': 'First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jun 22, 2017', 'snippet': 'Nivolumab has been associated with longer overall survival than docetaxel \namong patients with previously treated non–small-cell lung cancer...', 'thumbnail': 'https://serpapi.com/searches/67242b0e3b3c3238b924e5cb/images/796a6a638c68b4e0a0192e923c958b64f8a5c051aabb7f259cd9ed583742b87e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8376302123069763}",,,,,,,,,,['neutral'],neutral,1 NCT02675790,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2000146', 'title': 'Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa', 'source': 'The New England Journal of Medicine', 'date': 'Jun 24, 2020', 'snippet': 'Hydroxyurea with dose escalation had superior clinical efficacy to that of \nfixed-dose hydroxyurea, with equivalent safety.', 'thumbnail': 'https://serpapi.com/searches/67242b3c8a7c0972a22e3eff/images/1fe0d44d9e7f18856493190f7b379d4c400623f525ebfdaea9fec5633543199b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.4917817711830139}",,,,,,,,,,['neutral'],neutral,1 NCT01691521,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1403290', 'title': 'Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma', 'source': 'The New England Journal of Medicine', 'date': 'Sep 8, 2014', 'snippet': 'Some patients with severe asthma have frequent exacerbations associated \nwith persistent eosinophilic inflammation despite continuous...', 'thumbnail': 'https://serpapi.com/searches/67242b46360f4e3b5cd9a69e/images/8138e474412c1153a345f0cc365f18d7e3f571602f65648fbbb681b3d1683560.png', 'sentiment': 'negative', 'sentiment_prob': 0.5234540104866028}","{'position': 2, 'link': 'https://www.pulmonologyadvisor.com/news/severe-asthma-benefits-from-mepolizumab-regardless-of-background-therapies/', 'title': 'Mepolizumab Effective in Asthma Regardless of Background Controller Therapies', 'source': 'Pulmonology Advisor', 'date': 'Nov 1, 2019', 'snippet': 'Mepolizumab consistently reduced the annual rate of exacerbations in severe \neosinophilic asthma compared with placebo, according to research.', 'thumbnail': 'https://serpapi.com/searches/67242b46360f4e3b5cd9a69e/images/8138e474412c11536b153c32f6bc02bb25156f56ed8fc6650793afb5b0a60294.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5463080406188965}",,,,,,,,,"['negative', 'positive']",negative,0 NCT00122460,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0802656', 'title': 'Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Jan 27, 2017', 'snippet': 'Cetuximab is effective in platinum-resistant recurrent or metastatic \nsquamous-cell carcinoma of the head and neck. We investigated the efficacy \nof cetuximab...', 'thumbnail': 'https://serpapi.com/searches/67242b6788bcde41116354ec/images/cc05c169387494615167777ec17225bcac1c706c1181e5362b7261b084c6e8ab.png', 'sentiment': 'neutral', 'sentiment_prob': 0.752274751663208}",,,,,,,,,,['neutral'],neutral,1 NCT01492686,"{'position': 1, 'link': 'https://alsnewstoday.com/news/radicava-edaravone-slows-decline-als-poorer-lung-function/', 'title': 'Radicava Slows Decline in ALS Patients With Poorer Lung Function |...', 'source': 'ALS News Today', 'date': 'Jul 19, 2022', 'snippet': 'Post-hoc analysis showed slower progression in ALS patients on Radicava \n(edaravone), including those low FVC values; early start supported.', 'thumbnail': 'https://serpapi.com/searches/67242ffd707fd36741531b2d/images/64095e55515b5cff982e58cd07df0dfd3d1378b4623fbf017670fb48700cdad8.png', 'sentiment': 'negative', 'sentiment_prob': 0.537021815776825}","{'position': 2, 'link': 'https://alsnewstoday.com/news/als-early-radicava-lowers-risk-ventilation-hospitalization-mortality/', 'title': 'In ALS, early Radicava lowers risk of ventilation, hospitalization, mortality', 'source': 'ALS News Today', 'date': 'Aug 15, 2023', 'snippet': 'ALS patients in Study 19 on Radicava continuously were 53% less likely to \nhave those events over those who started it six months later.', 'thumbnail': 'https://serpapi.com/searches/67242ffd707fd36741531b2d/images/64095e55515b5cff3419bce7e151e12229f6ad1d12d31c7ed81b43fa983421b9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7491136193275452}","{'position': 3, 'link': 'https://www.empr.com/home/news/oral-suspension-formulation-of-edaravone-approved-for-als/', 'title': 'Oral Suspension Formulation of Edaravone Approved for ALS', 'source': 'Medical Professionals Reference', 'date': 'May 13, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Radicava ORS \n(edaravone) oral suspension for the treatment of adults with amyotrophic \nlateral sclerosis (...', 'thumbnail': 'https://serpapi.com/searches/67242ffd707fd36741531b2d/images/64095e55515b5cffa21a31d9f7bc67545b5a9a7c98f2b4bd27b137760e35c2cf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8913319110870361}","{'position': 4, 'link': 'https://alsnewstoday.com/news/radicava-suggests-more-real-world-data-needed-to-determine-efficacy-of-edaravone-in-als/', 'title': 'Radicava’s Effectiveness for ALS Not Established, Real-life Use Suggests', 'source': 'ALS News Today', 'date': 'Nov 17, 2020', 'snippet': 'A review of Radicava (edaravone), an approved amyotrophic lateral sclerosis \n(ALS) treatment, found the medication generally well tolerated in real-life \nuse by...', 'thumbnail': 'https://serpapi.com/searches/67242ffd707fd36741531b2d/images/64095e55515b5cff583054c5528622e933b5f7f5fb562970ab0b6e912a6f1dbb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6735977530479431}","{'position': 5, 'link': 'https://alsnewstoday.com/news/radicava-prolongs-survival-als-patients-study-japan/', 'title': 'Radicava Prolongs Survival in ALS Patients, Study from Japan Indicates', 'source': 'ALS News Today', 'date': 'Aug 18, 2021', 'snippet': 'Long-term treatment with Radicava (edaravone) is generally safe and nearly \ndoubles survival time in adults with amyotrophic lateral...', 'thumbnail': 'https://serpapi.com/searches/67242ffd707fd36741531b2d/images/64095e55515b5cffc84519553b8b4bc058f6daa649270a010a9b29c89391966d.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5691385865211487}",,,,,,"['negative', 'neutral', 'neutral', 'neutral', 'positive']",neutral,1 NCT02804750,"{'position': 1, 'link': 'https://cushingsdiseasenews.com/news/interim-phase-2-trial-data-shows-relacorilant-potential-manage-cortisol-effects-cushings/', 'title': ""In Phase 2 Cushing's Trial, Relacorilant Shows Early Positive Results"", 'source': ""Cushing's Disease News"", 'date': 'May 11, 2018', 'snippet': ""Relacorilant, developed by Corcept Therapeutics, may effectively manage the \neffects of excess cortisol in Cushing's syndrome patients,..."", 'thumbnail': 'https://serpapi.com/searches/6724300e30dfc1771aa82e92/images/0b0ef65c816baacb01d9febbfdcc7eb85fc56a5334d3d61000f9e8a322172e50.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6322821378707886}",,,,,,,,,,['positive'],positive,1 NCT03943264,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/clinical-hold-lifted-phase-2-trial-xpro1595-mild/', 'title': 'Clinical hold lifted for Phase 2 trial of XPro1595 in mild Alzheimer’s', 'source': ""Alzheimer's News Today"", 'date': 'Feb 22, 2024', 'snippet': ""The U.S. Food and Drug Administration (FDA) has lifted a clinical hold on a \nPhase 2 trial testing INmune Bio's investigational treatment..."", 'thumbnail': 'https://serpapi.com/searches/67243011a86921b7552efe19/images/d6308d658c6e933c299a8860c4cdaec5fa58cb26d97091ec1ea5ce7bbe129a31.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9154505133628845}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/07/13/xpro1595-may-promote-myelin-restoration-ms-mouse-study-finds/', 'title': 'XPro1595 may promote myelin restoration, new mouse study finds |...', 'source': 'Multiple Sclerosis News Today', 'date': 'Jul 13, 2023', 'snippet': 'Through the activation of two types of nervous system support cells, \nXPro1595 may promote myelin restoration that could help MS patients.', 'thumbnail': 'https://serpapi.com/searches/67243011a86921b7552efe19/images/d6308d658c6e933c820d92be200663114d471ce3ec969ec84be61167d7a1c7e8.png', 'sentiment': 'positive', 'sentiment_prob': 0.7108244299888611}","{'position': 3, 'link': 'https://alzheimersnewstoday.com/news/alzheimers-phase-2-trial-xpro1595-begins-dosing-patients/', 'title': 'Dosing Begins in Phase 2 Trial of XPro1595, Targeting Inflammation', 'source': ""Alzheimer's News Today"", 'date': 'Apr 20, 2022', 'snippet': ""A first patient has been dosed in a Phase 2 trial of XPro1595, which aims \nto treat mild Alzheimer's patients by lowering neuroinflammation."", 'thumbnail': 'https://serpapi.com/searches/67243011a86921b7552efe19/images/d6308d658c6e933c5b9b469137259278bd5e330e102fffb54f00bfe8cf46982a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.917678952217102}",,,,,,,,"['neutral', 'positive', 'neutral']",neutral,1 NCT02994927,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2023386', 'title': 'Avacopan for the Treatment of ANCA-Associated Vasculitis', 'source': 'The New England Journal of Medicine', 'date': 'Feb 17, 2021', 'snippet': 'In this randomized, controlled trial, we assigned patients with \nANCA-associated vasculitis in a 1:1 ratio to receive oral avacopan at a \ndose...', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d6820914636c00f3c5e526890d71aaa16f1cccc9d16f6f1aa557c92cd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.895490825176239}","{'position': 2, 'link': 'https://ancavasculitisnews.com/news/fda-approves-tavneos-avacopan-add-on-mpa-gpa-therapy/', 'title': 'FDA Approves Tavneos as Add-on Therapy for Severe MPA, GPA', 'source': 'ANCA Vasculitis News', 'date': 'Oct 11, 2021', 'snippet': 'The US Food and Drug Administration (FDA) has approved Tavneos (avacopan) \nas an add-on therapy for people with severe active microscopic polyangiitis \n(MPA) and...', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d682091462d621f862a6eea860448bc8bf032fc01d695733e41208c08.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7773008346557617}","{'position': 3, 'link': 'https://ancavasculitisnews.com/news/tavneos-plus-rituximab-aids-sustained-remission-aav/', 'title': 'Tavneos plus rituximab induction aids sustained remission with AAV', 'source': 'ANCA Vasculitis News', 'date': 'Nov 27, 2023', 'snippet': 'In a Phase 3 ADVOCATE trial, sustained one-year remission rates were higher \nin an AAV patient subgroup on rituximab induction plus Tavneos.', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d6820914629e180e949f0e4ac582a531d9df0fbe4a8ca01d56dd2e1ed.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7185574769973755}","{'position': 4, 'link': 'https://ancavasculitisnews.com/news/chemocentryx-on-track-present-topline-data-advocate-trial-avacopan/', 'title': ""AAV: ADVOCATE Trial's Topline Data Expected to be Presented This Year"", 'source': 'ANCA Vasculitis News', 'date': 'May 14, 2019', 'snippet': 'ChemoCentryx remains on track to report topline results later this year \nfrom its ongoing Phase 3 clinical trial assessing the safety and...', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d682091460753dedd7ecc744881a09168df5afe309ae474cd21b1fceb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8710752725601196}","{'position': 5, 'link': 'https://ancavasculitisnews.com/news/tavneos-better-than-prednisone-treating-aav-ear-nose-throat-symptoms/', 'title': 'Tavneos better than prednisone for treating ear, nose, throat symptoms', 'source': 'ANCA Vasculitis News', 'date': 'Jul 1, 2024', 'snippet': ""Topline data from the Phase 3 ADVOCATE clinical trial supported Tavneos' \napproval as an add-on to standard treatment for GPA, MPA."", 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d68209146ffa3c78128649b22b578d3c532496c7c6614556a8cdd1dab.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6747206449508667}","{'position': 6, 'link': 'https://ancavasculitisnews.com/news/anca-associated-vasculitis-remission-rates-high-with-tavenos-study/', 'title': 'ANCA-associated vasculitis remission rates high with Tavneos: Study', 'source': 'ANCA Vasculitis News', 'date': 'Apr 17, 2024', 'snippet': 'Tavneos (avacopan) safely and effectively promotes clinical remission in \npeople with newly diagnosed or relapsing ANCA-associated vasculitis (AAV),', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d682091462f3e4c5ae818f7d4b0d9e468eb8ed777d5515a42890865b0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5173897743225098}","{'position': 7, 'link': 'https://ancavasculitisnews.com/news/abstract-on-how-avacopan-affects-kidney-function-makes-committee-top-10-list/', 'title': 'Abstract on How Avacopan Affects Kidney Function Makes Top 10 List', 'source': 'ANCA Vasculitis News', 'date': 'Jun 16, 2021', 'snippet': 'Avacopan can improve kidney function in AAV patients to a greater extent \nthan steroids, especially among people with advanced kidney disease...', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d68209146a4133deced661712a0d119f0f63a929146a570e4e8d90b39.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7190611958503723}","{'position': 8, 'link': 'https://ancavasculitisnews.com/news/canada-tavneos-approval-add-on-treatment-severe-aav-mpa-gpa-anca-vasculitis/', 'title': 'Canada Approves Tavneos as Add-on Treatment for Severe AAV', 'source': 'ANCA Vasculitis News', 'date': 'Apr 27, 2022', 'snippet': 'Health Canada has approved the oral medicine Tavneos (avacopan) as an \nadd-on therapy to treat adults with severe ANCA-associated vasculitis (AAV).', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d682091463c5996b072bced7c86ba130f9d917a1ba7553f1c7180ecb1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7907763719558716}","{'position': 9, 'link': 'https://ancavasculitisnews.com/news/tavneos-mpa-gpa-approved-japan-marketed-by-kissei/', 'title': 'Tavneos for MPA, GPA Approved in Japan; Will Be Marketed by Kissei', 'source': 'ANCA Vasculitis News', 'date': 'Sep 29, 2021', 'snippet': 'Tavneos has been approved by the Japanese Ministry of Health, Labor, and \nWelfare for the treatment of MPA and GPA patients in Japan.', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d68209146e409b33de9945252fa006361a318ae59b31af1348bbaa67c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8002713918685913}","{'position': 10, 'link': 'https://ancavasculitisnews.com/news/tavneos-approved-european-union-oral-add-on-treatment-mpa-gpa/', 'title': 'Tavneos Approved in EU as Oral Add-on Treatment for MPA, GPA', 'source': 'ANCA Vasculitis News', 'date': 'Jan 24, 2022', 'snippet': 'The European Commission has approved Tavneos (avacopan) as an add-on \ntherapy for adults with severe granulomatosis polyangiitis (GPA) or \nmicroscopic...', 'thumbnail': 'https://serpapi.com/searches/6724303454605c243c1bc75f/images/1d66c27d68209146e8af079f685c5a7494feff2abba2df23ab252ff028cb5847.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7375460267066956}","['neutral', 'neutral', 'neutral', 'neutral', 'positive', 'neutral', 'positive', 'neutral', 'neutral', 'neutral']",neutral,1 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NCT03809767,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-023-02431-7', 'title': 'A first-in-human phase 1 study of nofazinlimab, an anti-PD-1 antibody, in advanced solid tumors and in combination with regorafenib in metastatic colorectal cancer', 'source': 'Nature', 'date': 'Sep 20, 2023', 'snippet': 'We assessed nofazinlimab, an anti-PD-1 antibody, in solid tumors and \ncombined with regorafenib in metastatic colorectal cancer (mCRC).', 'thumbnail': 'https://serpapi.com/searches/67242f4ac4bcf5b104d291a1/images/8edd052e7fb8175f79d06d8dd90949db8b27573f537b9cfb17bdd3305ded6fdb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8887736797332764}",,,,,,,,,,['neutral'],neutral,1 NCT02927262,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1902688', 'title': 'Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3 -Mutated AML', 'source': 'The New England Journal of Medicine', 'date': 'Oct 30, 2019', 'snippet': 'Patients with relapsed or refractory acute myeloid leukemia (AML) with \nmutations in the FMS-like tyrosine kinase 3 gene (FLT3) infrequently...', 'thumbnail': 'https://serpapi.com/searches/67242f51ea57e958c5952e64/images/393cedd00e1d3ae3824eadee89d0e71c2ce8d8550eedc7de64abfc723bca8fd1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7907082438468933}",,,,,,,,,,['neutral'],neutral,1 NCT02951767,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/news/fda-grants-atezolizumab-accelerated-approval-for-bladder-cancer/', 'title': 'FDA Grants Atezolizumab Accelerated Approval for Bladder Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Apr 18, 2017', 'snippet': 'The US Food and Drug Administration (FDA) has granted the PD-L1-targeting \nmonoclonal antibody atezolizumab (Tecentriq) accelerated approval for \nfirst-line...', 'thumbnail': 'https://serpapi.com/searches/67242d5fdc969fad1f5aec4f/images/de34a12306b6cb7a1b6ac2b107009b38a96c06d3766331a7b0edf8e8fe8546ca.jpeg', 'sentiment': 'neutral', 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motor neurons in ALS, orphan drug', 'source': 'ALS News Today', 'date': 'Oct 24, 2023', 'snippet': ""The U.S. Food and Drug Administration (FDA) has given orphan drug \ndesignation to CB03, Zhimeng Biopharma's small molecule treatment..."", 'thumbnail': 'https://serpapi.com/searches/67242d670e6db3745b1e3839/images/ca8479d98ec155a51301d0c3b0aed5c152e822aa1f692f4a74c1a299df9b4335.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7899766564369202}",,,,,,,,,,['neutral'],neutral,1 NCT03559699,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/mitapivat-safely-increases-hemoglobin-levels-in-patients-early-data-phase-1-trial/', 'title': 'SCD Trial Shows Mitapivat Safely Boosts Hemoglobin Levels in Patients', 'source': 'Sickle Cell Disease News', 'date': 'Jun 25, 2020', 'snippet': 'Early Phase 1 trial results show mitapivat safely increases hemoglobin \nlevels and lowers red blood cell damage in adults with sickle cell...', 'thumbnail': 'https://serpapi.com/searches/67242d6d6273fb28dc5d819a/images/d69360a40d24b8f009004ccfa300d230caa5c2826dd26d3e8ed6a5e4fb74eae0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5431870222091675}",,,,,,,,,,['neutral'],neutral,1 NCT05034952,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209870', 'title': 'Selective Inhibition of NaV1.8 with VX-548 for Acute Pain', 'source': 'The New England Journal of Medicine', 'date': 'Aug 2, 2023', 'snippet': 'The NaV1.8 voltage-gated sodium channel, expressed in peripheral \nnociceptive neurons, plays a role in transmitting nociceptive signals.', 'thumbnail': 'https://serpapi.com/searches/67242d7075f97436c9f2c186/images/0dea481f3471c7bbbddf28030e57c70c09636ad62b9ed7b22b945bb8c6a3884f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8272075057029724}",,,,,,,,,,['neutral'],neutral,1 NCT03301090,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/monoclonal-antibodies-against-mers-coronavirus-show-promise-phase-1-nih-sponsored-trial', 'title': 'Monoclonal antibodies against MERS coronavirus show promise in Phase 1 NIH-sponsored trial', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Feb 23, 2021', 'snippet': 'A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal \nantibodies (mAbs) directed against the coronavirus that causes Middle \nEast...', 'thumbnail': 'https://serpapi.com/searches/67242d866ad3c9c2f7a6a9d4/images/70f42141faa0919b8c2e2a293777893e4aaf7e21d4ceb86e9a564aa42fb39e79.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6738982200622559}",,,,,,,,,,['neutral'],neutral,1 NCT02720744,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-once-nightly-lumryz-for-patients-with-narcolepsy/', 'title': 'FDA Approves Once-Nightly Lumryz for Patients With Narcolepsy', 'source': 'Medical Professionals Reference', 'date': 'May 1, 2023', 'snippet': 'The Food and Drug Administration (FDA) has granted final approval to Lumryz \n(sodium oxybate) for the treatment of cataplexy or excessive daytime \nsleepiness in...', 'thumbnail': 'https://serpapi.com/searches/67242d9eb5ecbb920ddee1ec/images/19a538cc1be6df381d017a6ef4d93202ec0b66963e889e274d9fe864f3509817.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8342679738998413}","{'position': 2, 'link': 'https://www.pharmacytimes.com/view/expert-philosophical-about-pharmacy-services-how-community-health-worker-training-can-bolster-technician-s-role', 'title': 'Expert: ""Philosophical"" About Pharmacy Services, How Community Health Worker Training Can Bolster Technician’s Role', 'source': 'Pharmacy Times', 'date': 'Jul 7, 2023', 'snippet': 'Nancy Lyons, BSPharm, MBA, CDCES, VP, the Chief Pharmacy Officer at Health \nMart, a part of McKesson Corporation, expands on her first...', 'thumbnail': 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NCT02124772,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02321-8', 'title': 'Dabrafenib plus trametinib in BRAFV600E -mutated rare cancers: the phase 2 ROAR trial', 'source': 'Nature', 'date': 'Apr 14, 2023', 'snippet': 'Here we present final efficacy and safety results of a phase 2 basket trial \nof dabrafenib (BRAF kinase inhibitor) plus trametinib (MEK inhibitor) in \neight...', 'thumbnail': 'https://serpapi.com/searches/67242dad63a844f82690f941/images/ffb37f5d69497925ffaa4d3e337843e407381258cfaed41bf70da1fa7cdc404c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8969771862030029}",,,,,,,,,,['neutral'],neutral,1 NCT01872598,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/fda-approves-phase-3-trial-of-masitinib-alzheimers-disease/', 'title': 'FDA Greenlights Phase 3 Trial of Masitinib for Alzheimer’s Disease', 'source': ""Alzheimer's News Today"", 'date': 'Dec 20, 2022', 'snippet': ""AB Science is initiating a Phase 3 trial to evaluate the safety and \nefficacy of its candidate therapy masitinib in patients with mild to \nmoderate Alzheimer's..."", 'thumbnail': 'https://serpapi.com/searches/67242dbd4300ce9a4f716467/images/eae315ee454853bfbfcbdcefeebb0d6611d1ece919759e6dd7f0ca9cbddf4896.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8828580975532532}",,,,,,,,,,['neutral'],neutral,1 NCT04161495,"{'position': 1, 'link': 'https://hemophilianewstoday.com/news/altuviiio-approved-hemophilia-a-japan-taiwan/', 'title': 'Altuviiio approved as hemophilia A treatment in Japan and Taiwan |...', 'source': 'Hemophilia News Today', 'date': 'Sep 27, 2023', 'snippet': 'Regulators in Japan and Taiwan approved Altuviiio (efanesoctocog alfa) to \nprevent and control bleeds in children, adults with hemophilia A.', 'thumbnail': 'https://serpapi.com/searches/67242df7b6e4db286c8d19e1/images/1df8248236a540bba104aa81619706a365c424f9144504992f9f6043d9fbe570.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7902185916900635}","{'position': 2, 'link': 'https://www.empr.com/home/news/altuviiio-approved-as-once-weekly-factor-viii-therapy-for-hemophilia-a/', 'title': 'Altuviiio Approved as Once-Weekly Factor VIII Therapy for Hemophilia A', 'source': 'Medical Professionals Reference', 'date': 'Feb 24, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Altuviiio™ \n(antihemophilic factor [recombinant], Fc-VWF-XTEN fusion protein-ehtl),...', 'thumbnail': 'https://serpapi.com/searches/67242df7b6e4db286c8d19e1/images/1df8248236a540bbfb899ede552930f90de4f6b9667b9d8419cf45978b0cfaec.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.744762659072876}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02480153,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2019/11/21/fda-approves-abrilada-biosimilar-humira-for-adults-with-active-ankylosing-spondylitis/', 'title': 'Adults with Active Ankylosing Spondylitis Have Option of Abrilada, Biosimilar to Humira, FDA Says', 'source': 'Ankylosing Spondylitis News', 'date': 'Nov 21, 2019', 'snippet': 'Abrilada (adalimumab-afzb), a biosimilar to Humira (adalimumab), has been \napproved by the US Food and Drug Administration (FDA) to treat people with \nseven...', 'thumbnail': 'https://serpapi.com/searches/67242dfe9fd3095eab7ea4cd/images/8c8f4fc5a36b2b6d9cfeb09fe46aefb4b2ba509ae6dcb477a1ff6bb2f7ed5d05.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8899936676025391}",,,,,,,,,,['neutral'],neutral,1 NCT01031901,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0073-2', 'title': 'Cutaneous neurofibromas in the genomics era: current understanding and open questions', 'source': 'Nature', 'date': 'Apr 26, 2018', 'snippet': 'Cutaneous neurofibromas (cNF) are a nearly ubiquitous symptom of \nneurofibromatosis type 1 (NF1), a disorder with a broad phenotypic \nspectrum...', 'thumbnail': 'https://serpapi.com/searches/67242e12b6a79c9a27f66914/images/270af7f168f63a773e807b5b131160c7c76d87e68ae472cc8e93400067d4e838.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8099650740623474}",,,,,,,,,,['neutral'],neutral,1 NCT00111319,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0801479', 'title': 'Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma', 'source': 'The New England Journal of Medicine', 'date': 'Aug 28, 2008', 'snippet': 'The standard treatment for patients with multiple myeloma who are not \ncandidates for high-dose therapy is melphalan and prednisone.', 'thumbnail': 'https://serpapi.com/searches/67242e3b3b3c3238b924e696/images/82aca6061ffd40b35e4bbc4d2b3ff66c7e47dcb727c7bf8d8e7a75a90ce536fd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8991239666938782}",,,,,,,,,,['neutral'],neutral,1 NCT03830203,"{'position': 1, 'link': 'https://www.empr.com/home/news/generics-news/tofidence-tocilizumab-biosimilar-approved/', 'title': 'FDA Approves Tofidence, the First Biosimilar to Tocilizumab', 'source': 'Medical Professionals Reference', 'date': 'Oct 2, 2023', 'snippet': 'The Food and Drug Administration has approved Tofidence (tocilizumab-bavi), \nthe first biosimilar to Actemra (tocilizumab).', 'thumbnail': 'https://serpapi.com/searches/67242e5cc4bcf5b0c882c067/images/0aed7cca41ad63d69c9f227029a79b0acb6329976dd5dd8f108c80b6a3915694.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5141994953155518}","{'position': 2, 'link': 'https://investors.biogen.com/news-releases/news-release-details/biogen-and-bio-thera-solutions-present-positive-phase-3-data', 'title': 'Biogen and Bio-Thera Solutions Present Positive Phase 3 Data for Tocilizumab Biosimilar Candidate at the Annual European Congress of Rheumatology (EULAR 2022)', 'source': 'Biogen', 'date': 'Jun 3, 2022', 'snippet': 'CAMBRIDGE, Mass. and GUANGZHOU, China, June 03, 2022 (GLOBE NEWSWIRE) -- \nBiogen Inc. (Nasdaq: BIIB) and Bio-Thera Solutions, Ltd. (688177.', 'thumbnail': 'https://serpapi.com/searches/67242e5cc4bcf5b0c882c067/images/0aed7cca41ad63d6bc165bb1e032ad5107eed26374b85b9346a2fb7f88ce8e1f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7950824499130249}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00700102,"{'position': 1, 'link': 'https://theoncologist.onlinelibrary.wiley.com/doi/10.1002/onco.13971', 'title': 'A Long‐Term Extension Study of Bevacizumab in Patients With Solid Tumors - Oza - 2021', 'source': 'The Oncologist', 'date': 'Sep 9, 2021', 'snippet': 'Abstract Background Bevacizumab has been studied in numerous clinical \ntrials in multiple types of cancer; however, patients may receive...', 'thumbnail': 'https://serpapi.com/searches/67242e7c21b01bfe522bb70d/images/2fb2aa638f90a0f457f6b6d8dc69eb90410bf66a871e710e8a994cc4f2c525d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9322308897972107}",,,,,,,,,,['neutral'],neutral,1 NCT00193856,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/cohort-study-identified-optimal-minimum-treatment-duration-for-adt-in-high-risk-prostate-cancer', 'title': 'Cohort Study Identified Optimal Minimum Treatment Duration for ADT in High-Risk Prostate Cancer', 'source': 'Cancer Network', 'date': 'Jun 24, 2022', 'snippet': 'A cohort study found that the optimal minimum duration for androgen \ndeprivation therapy (ADT) plus high-dose external beam radiotherapy (EBRT) \nwas more than 18...', 'thumbnail': 'https://serpapi.com/searches/67242e8eee4682bcee5df66d/images/bb69cc8452ec18cdc693ddf5c6dd4b3fb32bb83e74275943cc34114b169a3de0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9076136350631714}",,,,,,,,,,['neutral'],neutral,1 NCT03342053,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/ionis-httrx-rg6042/', 'title': 'Tominersen for Huntington’s disease', 'source': ""Huntington's Disease News"", 'date': 'Jun 6, 2024', 'snippet': 'Last updated June 6, 2024, by Marisa Wexler, MS ✓ Fact-checked by Marta \nFigueiredo, PhD. How tominersen works. Administration. Clinical trials. \nSide effects...', 'thumbnail': 'https://serpapi.com/searches/67242e8f7f3719505b76151f/images/f37818a2a2fa9f6fb8702d3cb931032a918637bc0570e89ceca8e7452f583f66.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9408097863197327}","{'position': 2, 'link': 'https://www.nature.com/articles/s41587-021-00955-y', 'title': 'Questions swirl around failures of disease-modifying Huntington’s drugs', 'source': 'Nature', 'date': 'Jun 10, 2021', 'snippet': ""Researchers hope that antisense oligo clinical trial failures in \nHuntington's will shed light on mechanism and drug biodistribution and \ngalvanize ongoing drug..."", 'thumbnail': 'https://serpapi.com/searches/67242e8f7f3719505b76151f/images/f37818a2a2fa9f6f28aff94da1f6f9b8b05cf71ccb55e4d00073b563b1535308.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6443971395492554}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03761537,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/bjd.20832', 'title': 'Tralokinumab plus topical corticosteroids in adults with severe atopic dermatitis and inadequate response to or intolerance of ciclosporin A: a placebo-controlled, randomized, phase III clinical trial (ECZTRA 7)', 'source': 'Wiley Online Library', 'date': 'Oct 26, 2021', 'snippet': 'Tralokinumab 300 mg plus TCS as needed was effective and well tolerated in \npatients with severe AD whose disease was not adequately controlled with \nCSA.', 'thumbnail': 'https://serpapi.com/searches/67242e92c76a3af3eaa52198/images/7ca7e219b71f5dc9a2d6c816269dd479450f54a5efdc3ccdd33e324064e97376.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7460282444953918}",,,,,,,,,,['neutral'],neutral,1 NCT01522469,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-018-08263-x', 'title': 'Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms', 'source': 'Nature', 'date': 'Jan 16, 2019', 'snippet': 'FLT3 mutations are prevalent in AML patients and confer poor prognosis. \nCrenolanib, a potent type I pan-FLT3 inhibitor, is effective against...', 'thumbnail': 'https://serpapi.com/searches/672430857a12fd607b597a2b/images/9a37cc896f9fa93a456effef02447ff4e6ae4e8d80a2dc001d0521a779c67b0b.png', 'sentiment': 'negative', 'sentiment_prob': 0.5016843676567078}",,,,,,,,,,['negative'],negative,0 NCT04125732,"{'position': 1, 'link': 'https://www.cgtlive.com/view/thomas-povsic-unmet-needs-refractory-angina-xc001', 'title': 'Thomas Povsic, MD, PhD, on Addressing Unmet Needs in Refractory Angina With Gene Therapy', 'source': 'CGTLive®', 'date': 'Aug 25, 2023', 'snippet': '“The phase 1 study results, in general, suggested that there was a dose \nresponse with greater efficacy observed in patients in terms of a...', 'thumbnail': 'https://serpapi.com/searches/672430f7ef60cbc4eeb398df/images/3437428e67e47902481ae31ae22f2d3e26a0a731e0bea6a58c785dba8f96a154.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7850585579872131}",,,,,,,,,,['neutral'],neutral,1 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complete response \nletter to Galera Therapeutics related to the new drug application for \navasopasem...', 'thumbnail': 'https://serpapi.com/searches/672430fc24296a895db7b630/images/04ad23c771d7f516708cdba2186ad60ce6a7d9994328ff974f9dcd2521445c19.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5011367201805115}",,,,,,,,,,['neutral'],neutral,1 NCT02855944,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2021/01/05/phase-3-trial-confirms-rubraca-clinical-benefit-over-chemotherapy-top-line-data/', 'title': 'Rubraca Shows Clinical Benefit Over Chemo for Advanced Ovarian Cancer', 'source': 'Ovarian Cancer News Today', 'date': 'Jan 5, 2021', 'snippet': 'Rubraca (rucaparib) is superior to chemotherapy at prolonging life without \ndisease worsening in people with advanced ovarian cancer who received at \nleast two...', 'thumbnail': 'https://serpapi.com/searches/67245b6a708e2e98ffa84bd3/images/2bb10887c058c58365d9e01109177908a6636bda0bbdfdc1d150b45c01a86eac.jpeg', 'sentiment': 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exacerbation of...', 'thumbnail': 'https://serpapi.com/searches/67245ba359f911b9ca52eeb9/images/93d240225d45b3213de3ac29f70fe5aead9f43b4594fa74d8a1d5520945d3fe4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8938841223716736}",,,,,,,,,,['neutral'],neutral,1 NCT00136981,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa071359', 'title': 'Effect of Torcetrapib on Carotid Atherosclerosis in Familial Hypercholesterolemia', 'source': 'The New England Journal of Medicine', 'date': 'Jul 5, 2017', 'snippet': 'Torcetrapib, an inhibitor of cholesteryl ester transfer protein, may reduce \natherosclerotic vascular disease by increasing levels of high-density \nlipoprotein (...', 'thumbnail': 'https://serpapi.com/searches/67245bb89872179945fc4a7f/images/c7a76fdb2ee9c6f2d60de5a5a8215ce71d68f92c07767d16bd8105689f534c93.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8226796984672546}",,,,,,,,,,['neutral'],neutral,1 NCT04015076,"{'position': 1, 'link': 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'date': 'Nov 9, 2016', 'snippet': 'Advaxis has begun its Phase 3 clinical trial evaluating axalimogene \nfilolisbac, or AXAL, in women with high-risk, locally advanced cervical...', 'thumbnail': 'https://serpapi.com/searches/67245c6fa9210b55286be393/images/eab54731a458ff922abe4e11c3d1feeab3afbe841ed2d168f647d2fd763a3b3e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9055874943733215}",,,,,,,,,,['neutral'],neutral,1 NCT00046930,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-022-00736-z', 'title': 'Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999', 'source': 'Nature', 'date': 'Sep 23, 2022', 'snippet': ""Integrative analysis identifies an older female-linked AML patient group \nwith better risk in ECOG-ACRIN Cancer Research Group's clinical trial."", 'thumbnail': 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marker of nerve \ndamage, are associated with long-term disability progression in people \nwith...', 'thumbnail': 'https://serpapi.com/searches/67245c8d17b10eb84e16d054/images/81beefbb6c766536605ec9fcdd010f79f992342d9ce8e4cb6889795731557c92.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8781910538673401}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT00805194,"{'position': 1, 'link': 'https://www.thelancet.com/article/S1470-2045(13)70586-2/abstract', 'title': 'Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial', 'source': 'The Lancet', 'date': 'Jan 9, 2014', 'snippet': 'The phase 3 LUME-Lung 1 study assessed the efficacy and safety of docetaxel \nplus nintedanib as second-line therapy for non-small-cell lung cancer \n(NSCLC).', 'thumbnail': 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Lilly plans to complete...', 'thumbnail': 'https://serpapi.com/searches/67245cc15bb6a2d585edb93d/images/c6feaefafa3099ffaf7776804ca8b42695e640ea0229785aa51224b92c8bad73.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6582523584365845}","{'position': 3, 'link': 'https://www.empr.com/home/news/zepbound-approved-for-chronic-weight-management/', 'title': 'Zepbound Approved for Chronic Weight Management', 'source': 'Medical Professionals Reference', 'date': 'Nov 8, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Zepbound™ (tirzepatide) \nas an adjunct to a reduced-calorie diet and increased physical...', 'thumbnail': 'https://serpapi.com/searches/67245cc15bb6a2d585edb93d/images/c6feaefafa3099ffa24316e1aaf69088d7b556b9733dc746ad14f2680bd7abf8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6654108166694641}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT00370331,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/home/topics/anemia/alvaiz-approved-for-itp-thrombocytopenia-with-hep-c-and-severe-aplastic-anemia/', 'title': 'Alvaiz Approved for ITP, Thrombocytopenia With Hep C, and Severe Aplastic Anemia', 'source': 'Hematology Advisor', 'date': 'Dec 5, 2023', 'snippet': 'The Food and Drug Administration has approved Alvaiz (eltrombopag tablets), \na thrombopoietin receptor agonist.', 'thumbnail': 'https://serpapi.com/searches/67245cdafda26d2cf83eaa11/images/1d42372689bd16d93c09a27d0c0b070717bccb6599ae98072de81c043070b382.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7984627485275269}",,,,,,,,,,['neutral'],neutral,1 NCT03333915,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-021-01632-2', 'title': 'Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours', 'source': 'Nature', 'date': 'Nov 18, 2021', 'snippet': 'Pamiparib, a PARP1/2 inhibitor, demonstrated antitumor activity in \npreclinical models. 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This is mainly due to drug resistance, recurrence,...', 'thumbnail': 'https://serpapi.com/searches/67245ce3d364b4f6fa6e080f/images/e0c8de132c7521e2a3d0cc8e8d8eb6619a9b84933093ecf7c5125295f55f05cf.png', 'sentiment': 'negative', 'sentiment_prob': 0.5102999210357666}",,,,,,,,,,['negative'],negative,0 NCT04828005,"{'position': 1, 'link': 'https://www.empr.com/home/news/opvee-nasal-spray-approved-for-treatment-of-opioid-overdose/', 'title': 'Opvee Nasal Spray Approved for Treatment of Opioid Overdose', 'source': 'Medical Professionals Reference', 'date': 'May 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Opvee (nalmefene) nasal \nspray for the emergency treatment of known or suspected overdose induced by \nnatural...', 'thumbnail': 'https://serpapi.com/searches/67245d01642c3189bcbd653f/images/56f8589d225e7517bb76d6f406a03db6dde6821b0992f8b28be781ad86150adc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8920722007751465}",,,,,,,,,,['neutral'],neutral,1 NCT02292654,"{'position': 1, 'link': 'https://www.nature.com/articles/s41436-021-01156-3', 'title': 'One-year results of a clinical trial of olipudase alfa enzyme replacement therapy in pediatric patients with acid sphingomyelinase deficiency', 'source': 'Nature', 'date': 'Apr 19, 2021', 'snippet': 'In this study in children with chronic ASMD, olipudase alfa was generally \nwell-tolerated with significant, comprehensive improvements in disease \npathology.', 'thumbnail': 'https://serpapi.com/searches/67245e0635853912a0cb1c41/images/f78f705708f82a8db7a1568fd0ec8da48920b5b337e497ceae010518c79bceb2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.777836799621582}",,,,,,,,,,['neutral'],neutral,1 NCT00078611,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa054693', 'title': 'Evaluation of Patients Treated with Natalizumab for Progressive Multifocal Leukoencephalopathy', 'source': 'The New England Journal of Medicine', 'date': 'Mar 2, 2006', 'snippet': 'We invited patients who had participated in clinical trials in which they \nreceived recent or long-term treatment with natalizumab for...', 'thumbnail': 'https://serpapi.com/searches/67245f47e1d1adc069a091ae/images/2b52bed45f0316f4f179bf0cd3ac8c0f3c00fd8e0e3edff5516efa4c7a6855c1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9142276048660278}",,,,,,,,,,['neutral'],neutral,1 NCT00203060,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0809335', 'title': ""A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease"", 'source': 'The New England Journal of Medicine', 'date': 'Sep 24, 2009', 'snippet': ""A therapy that slows disease progression is the major unmet need in \nParkinson's disease.In this double-blind trial, we examined the..."", 'thumbnail': 'https://serpapi.com/searches/67245f71910986cafe52cba7/images/1e966702e475297816ada0f3f077175f9b840d9e3de85a9ec4f4f3c86cce3e25.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7325910925865173}",,,,,,,,,,['neutral'],neutral,1 NCT04505722,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2034201', 'title': 'Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine', 'source': 'The New England Journal of Medicine', 'date': 'Jan 13, 2021', 'snippet': 'Efficacious vaccines are urgently needed to contain the ongoing coronavirus \ndisease 2019 (Covid-19) pandemic of infection with severe acute...', 'thumbnail': 'https://serpapi.com/searches/672460a221b01bfe522bc17c/images/54d600bcfd75c362c9cbb0219183a079cf889635fcff8dcde12825f0b727a055.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5869097113609314}","{'position': 2, 'link': 'https://www.nature.com/articles/s41564-022-01262-1', 'title': 'Immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial', 'source': 'Nature', 'date': 'Nov 10, 2022', 'snippet': 'Measuring immune correlates of disease acquisition and protection in the \ncontext of a clinical trial is a prerequisite for improved vaccine...', 'thumbnail': 'https://serpapi.com/searches/672460a221b01bfe522bc17c/images/54d600bcfd75c3627c8b9f172cfca69d13565b4d69f96f9865f934348c882b02.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7268779873847961}","{'position': 3, 'link': 'https://www.pulmonologyadvisor.com/news/jansson-covid19-vaccine-granted-emergency-use-authorization-2/', 'title': 'Janssen’s Single-Shot COVID-19 Vaccine Receives Emergency Use Authorization', 'source': 'Pulmonology Advisor', 'date': 'Mar 4, 2021', 'snippet': ""The Food and Drug Administration (FDA) has granted Emergency Use \nAuthorization (EUA) to Janssen's single-dose vaccine for active \nimmunization to prevent..."", 'thumbnail': 'https://serpapi.com/searches/672460a221b01bfe522bc17c/images/54d600bcfd75c3623a30058101ae1cf1a402c1413f42c8847452e9b56f8fd9f5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.909311830997467}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01986881,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2004967', 'title': 'Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Sep 23, 2020', 'snippet': 'Among patients with type 2 diabetes and atherosclerotic cardiovascular \ndisease, ertugliflozin was noninferior to placebo with respect to major \nadverse...', 'thumbnail': 'https://serpapi.com/searches/67246147a2e99cbceea0bcbc/images/fe5166bd862bf6a1ff383ddb578e94d0a82a8720cfdd7cc221148d862a8587b9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6275863647460938}",,,,,,,,,,['neutral'],neutral,1 NCT03722147,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01600-7', 'title': 'Long-term survival benefit of anti-PD-1 therapy in patients with relapsed or refractory classical Hodgkin lymphoma', 'source': 'Nature', 'date': 'Sep 20, 2023', 'snippet': 'Anti-programmed cell death-1 (anti-PD-1) therapies have shown a favorable \nefficacy and good tolerance for relapsed or refractory (r/r) classical \nHodgkin...', 'thumbnail': 'https://serpapi.com/searches/67245df4a2e99cbd222de05b/images/99260a262f535e6cdfa81c635474cbcc698f6acb7ce07ca11153df1dd2b9fa9d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.668369472026825}",,,,,,,,,,['neutral'],neutral,1 NCT01982942,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1803583', 'title': 'Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis', 'source': 'The New England Journal of Medicine', 'date': 'Aug 29, 2018', 'snippet': 'Ibudilast was associated with slower progression of brain atrophy than \nplacebo but was associated with higher rates of gastrointestinal side \neffects, headache,...', 'thumbnail': 'https://serpapi.com/searches/67245ec848c97dfdbdfd91c7/images/89c0b26675ea13d42c8bca3d9e6db39fb4fe9e0bc7352ecf346428d5953b4cf7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.625451922416687}","{'position': 2, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2021/08/19/medicinova-planning-phase-3-ibudilast-trial-secondary-progressive-ms/', 'title': 'Phase 3 Trial of Ibudilast in Secondary Progressive MS Being Planned', 'source': 'Multiple Sclerosis News Today', 'date': 'Aug 19, 2021', 'snippet': 'MediciNova is planning to launch a Phase 3 clinical trial that will \nevaluate its investigational oral candidate ibudilast (MN-166) in people \nwith secondary...', 'thumbnail': 'https://serpapi.com/searches/67245ec848c97dfdbdfd91c7/images/89c0b26675ea13d47e59701f31e19d3d5d78d066ab3f56abaacec8298c7f941e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8921599388122559}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/12/18/ibudilast-interferon-beta-european-patent-ms/', 'title': 'Ibudilast plus interferon-beta to get European patent for progressive MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Dec 18, 2023', 'snippet': 'A European patent will cover various uses of ibudilast in combination with \ninterferon-beta medications in treating progressive MS forms.', 'thumbnail': 'https://serpapi.com/searches/67245ec848c97dfdbdfd91c7/images/89c0b26675ea13d4d9b99c07973c8f960957ced1f9c1f5d12de27ea088a7b0a1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7368255853652954}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04535531,"{'position': 1, 'link': 'https://www.contemporarypediatrics.com/view/fda-approves-prescription-berdazimer-gel-10-3-to-treat-molluscum-contagiosum', 'title': 'FDA approves prescription berdazimer gel, 10.3% to treat molluscum contagiosum', 'source': 'Contemporary Pediatrics', 'date': 'Jan 5, 2024', 'snippet': 'Berdazimer gel, 10.3% demonstrated positive, topline data in the phase 3 \nrandomized clinical B-SIMPLE4 trial (NCT04535531) that featured a...', 'thumbnail': 'https://serpapi.com/searches/67245ed3b28e6b6e596def5f/images/4920c5d15701406f790422355e966c75a59c94017698338601251ac511cad129.png', 'sentiment': 'positive', 'sentiment_prob': 0.5087462663650513}","{'position': 2, 'link': 'https://www.empr.com/home/news/topical-antiviral-gel-looks-promising-for-molluscum-contagiosum/', 'title': 'Topical Antiviral Gel Looks Promising for Molluscum Contagiosum', 'source': 'Medical Professionals Reference', 'date': 'Jun 11, 2021', 'snippet': 'Positive topline results were announced from a pivotal phase 3 study \nevaluating SB206, a topical antiviral gel, for the treatment of molluscum \ncontagiosum.', 'thumbnail': 'https://serpapi.com/searches/67245ed3b28e6b6e596def5f/images/4920c5d15701406f8aa3fab66b359c79dc8b66546ad5f33041621aef8438ec62.png', 'sentiment': 'positive', 'sentiment_prob': 0.8182651996612549}",,,,,,,,,"['positive', 'positive']",positive,1 NCT04774237,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20211130005414/en/Visus-Therapeutics-Announces-Positive-Topline-Clinical-Data-from-Phase-2-VIVID-Study-of-BRIMOCHOL-for-the-Treatment-of-Presbyopia', 'title': 'Visus Therapeutics Announces Positive Topline Clinical Data from Phase 2 VIVID Study of BRIMOCHOL for the Treatment of Presbyopia', 'source': 'Business Wire', 'date': 'Nov 30, 2021', 'snippet': 'Visus Therapeutics Inc., a clinical-stage pharmaceutical company focused on \ndeveloping innovative ophthalmic therapies to improve vision for...', 'thumbnail': 'https://serpapi.com/searches/67245ed6ce1e10a3d76f2836/images/f5e387c99a08f34e2652be1910c16a4fa7b71b695fb6922c39eddc66735f8a71.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5042712092399597}",,,,,,,,,,['neutral'],neutral,1 NCT05219669,"{'position': 1, 'link': 'https://www.empr.com/home/news/opvee-nasal-spray-approved-for-treatment-of-opioid-overdose/', 'title': 'Opvee Nasal Spray Approved for Treatment of Opioid Overdose', 'source': 'Medical Professionals Reference', 'date': 'May 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Opvee (nalmefene) nasal \nspray for the emergency treatment of known or suspected overdose induced by \nnatural...', 'thumbnail': 'https://serpapi.com/searches/67245f1972f7163d8322042d/images/fee18490e5542a6716cb387e5bb55c571d12f4dd5c13771f3ba46d09a7aafe62.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8920722007751465}",,,,,,,,,,['neutral'],neutral,1 NCT02342379,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-021-81841-0', 'title': 'Phase 2 trial of hypoxia activated evofosfamide (TH302) for treatment of recurrent bevacizumab-refractory glioblastoma', 'source': 'Nature', 'date': 'Jan 27, 2021', 'snippet': 'Evofosfamide (Evo or TH302) is a hypoxia-activated prodrug which is reduced \nleading to the release of alkylating agent...', 'thumbnail': 'https://serpapi.com/searches/67245f285416d82ea72819bf/images/e5f780a66edc0a5254330f8824b839d41367d1a4f238f6ba2721ef993650b68e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8631384968757629}",,,,,,,,,,['neutral'],neutral,1 NCT03777332,"{'position': 1, 'link': 'https://www.nature.com/articles/s41433-021-01766-w', 'title': 'An update on long-acting therapies in chronic sight-threatening eye diseases of the posterior segment: AMD, DMO, RVO, uveitis and glaucoma', 'source': 'Nature', 'date': 'Jan 1, 2022', 'snippet': 'In the real-world setting, there is suboptimal compliance with treatments \nthat require frequent administration and assessment visits.', 'thumbnail': 'https://serpapi.com/searches/67245e5974f0a4921705035b/images/7fc408c8d825ff2cf15b5b79662883f2f2da5fc21f3bd04956be9cd334dfc2e1.png', 'sentiment': 'negative', 'sentiment_prob': 0.590781033039093}",,,,,,,,,,['negative'],negative,0 NCT05566639,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-39376-7', 'title': 'Safety and immunogenicity of a phase 1/2 randomized clinical trial of a quadrivalent, mRNA-based seasonal influenza vaccine (mRNA-1010) in healthy adults: interim analysis', 'source': 'Nature', 'date': 'Jun 19, 2023', 'snippet': 'Despite vaccine availability, influenza remains a substantial global public \nhealth concern. Here, we report interim findings on the primary...', 'thumbnail': 'https://serpapi.com/searches/67245e6df93388521a29bd7b/images/c21acaf6909995964565485dfb6cd3248cbc21b1703be95e3a980fc7ad3ac0af.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8802207112312317}",,,,,,,,,,['neutral'],neutral,1 NCT03536143,"{'position': 1, 'link': 'https://www.cgtlive.com/view/krystal-dystrophic-epidermolysis-bullosa-gene-therapy-b-vec-under-review-eu', 'title': 'Krystal’s Dystrophic Epidermolysis Bullosa Gene Therapy B-VEC Under Review in EU', 'source': 'CGTLive®', 'date': 'Nov 27, 2023', 'snippet': ""An investigational gene therapy intended to treat dystrophic epidermolysis \nbullosa (DEB), has been validated by the European Medicines Agency's (EMA) \nCommittee..."", 'thumbnail': 'https://serpapi.com/searches/67245e72b4e8d64861817c4b/images/5dae00e588cb63fe380fb87cb0e72f56687ad23cf6ffe6708927031f252e3b93.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8852711319923401}","{'position': 2, 'link': 'https://epidermolysisbullosanews.com/news/first-rdeb-adult-patients-fare-well-clinical-trial-gene-therapy-kb103/', 'title': 'First RDEB Adult Patients Fare Well in Clinical Trial With Gene Therapy KB103', 'source': 'Epidermolysis Bullosa News', 'date': 'Oct 17, 2018', 'snippet': 'Read about positive results from the first two adult RDEB patients treated \nwith the topical gene therapy candidate KB103.', 'thumbnail': 'https://serpapi.com/searches/67245e72b4e8d64861817c4b/images/5dae00e588cb63fecc05a0f7cc45de67208e6c5448a81ee9d28dff5d2f0d484f.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6569815874099731}","{'position': 3, 'link': 'https://www.cgtlive.com/view/upcoming-fda-decisions-for-rare-diseases-in-2023', 'title': 'Upcoming FDA Decisions for Rare Diseases in 2023', 'source': 'CGTLive®', 'date': 'Feb 28, 2023', 'snippet': 'CGTLive is taking a look at some of the upcoming FDA decisions on selected \ngene and cell therapies for rare diseases.', 'thumbnail': 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obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial', 'source': 'Nature', 'date': 'Aug 27, 2023', 'snippet': 'In the STEP-HFpEF trial, semaglutide improved symptoms, physical \nlimitations and exercise function and reduced body weight in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/67245e7b1b4e342854b6ebcb/images/a75caf3062c053b0e1a26d3036062967a169ba34560932d1c03edc6576562d12.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7419707179069519}","{'position': 3, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.067505', 'title': 'Effects of Semaglutide on Symptoms, Function, and Quality of Life in Patients With Heart Failure With Preserved Ejection Fraction and Obesity: A Prespecified Analysis of the STEP-HFpEF Trial | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 12, 2023', 'snippet': 'BACKGROUND:Patients with heart failure (HF) with preserved ejection \nfraction (HFpEF) and obesity experience a high burden of symptoms and...', 'thumbnail': 'https://serpapi.com/searches/67245e7b1b4e342854b6ebcb/images/a75caf3062c053b0179db9c1844e52455d98806b3db505c1abc2fb72627aef38.png', 'sentiment': 'neutral', 'sentiment_prob': 0.769500195980072}","{'position': 4, 'link': 'https://finance.yahoo.com/news/novo-nordisk-announces-presentation-data-120000906.html', 'title': 'Novo Nordisk announces presentation of data from key semaglutide clinical trials in diabetes, obesity and chronic kidney disease at the 84th Scientific Sessions of the American Diabetes Association', 'source': 'Yahoo Finance', 'date': 'Jun 18, 2024', 'snippet': 'FLOW kidney outcomes trial data evaluating efficacy and safety of \nonce-weekly semaglutide 1.0 mg in people with type 2 diabetes1SELECT...', 'thumbnail': 'https://serpapi.com/searches/67245e7b1b4e342854b6ebcb/images/a75caf3062c053b072c1cb1e53657d5eb5dedcd1394841d4f2ce0bc63fb7071c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'Oct 9, 2020', 'snippet': 'Ibrutinib is an oral inhibitor of Bruton tyrosine kinase (BTK) that \nreceived accelerated approval by the U.S. Food and Drug Administration...', 'thumbnail': 'https://serpapi.com/searches/67245f8418787da3d4090e03/images/aea837cf8bfbefe077c27a911248961b2b054132120307a28a0c1551c734e9a0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8486211895942688}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02218736,"{'position': 1, 'link': 'https://www.nih.gov/news-events/news-releases/fast-fail-trial-shows-new-approach-identifying-brain-targets-clinical-treatments', 'title': 'Fast-fail trial shows new approach to identifying brain targets for clinical treatments', 'source': 'National Institutes of Health (NIH) (.gov)', 'date': 'Mar 30, 2020', 'snippet': 'NIH-funded study identifies receptor as possible target for treating \nanhedonia.', 'thumbnail': 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Clinical Stability of Patients With Heart Failure and a Reduced Ejection Fraction:', 'source': 'American Heart Association Journals', 'date': 'Oct 21, 2020', 'snippet': 'Background:Empagliflozin reduces the risk of cardiovascular death or \nhospitalization for heart failure in patients with heart failure and a...', 'thumbnail': 'https://serpapi.com/searches/6724603189055ecfb6d62741/images/cf11e2f19678410468986eb534673d27a41370fe9c92524bd6427b81ef08d033.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8130537271499634}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01969721,"{'position': 1, 'link': 'https://lungdiseasenews.com/2016/02/10/lung-function-copd-patients-shows-promise-stiolto-respimat-inhalation-spray/', 'title': 'Lung Function in COPD Patients Shows Promise With STIOLTO RESPIMAT Inhalation Spray', 'source': 'Lung Disease News', 'date': 'Feb 10, 2016', 'snippet': ""Read about promising data on Boehringer Ingelheim' STIOLTO RESPIMAT, which \nis able to improve lung function 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Randomized Study', 'source': 'Frontiers', 'date': 'Apr 29, 2022', 'snippet': '1Department of Radiation Oncology, National Cancer Center/National Clinical \nResearch Center for Cancer/Cancer Hospital, Chinese Academy of...', 'thumbnail': 'https://serpapi.com/searches/67245fe3d0c983711b6fcd01/images/5e21eb0c4ab0d3f121f28df64c0a9ae95b4dd35758b844d4af080212d4842ed6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9293925762176514}",,,,,,,,,,['neutral'],neutral,1 NCT00585195,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1406766', 'title': 'Crizotinib in ROS1 -Rearranged Non–Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Apr 30, 2018', 'snippet': 'In this study, crizotinib showed marked antitumor activity in patients with \nadvanced ROS1-rearranged NSCLC.', 'thumbnail': 'https://serpapi.com/searches/67245fe6c821274057f72961/images/3f3d07e9ef171b70c9b111a6d2201875b04c2a57f4661c98a59cfe5f3f046e08.jpeg', 'sentiment': 'neutral', 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Formulation of Infliximab, Approved for IBD', 'source': 'Medical Professionals Reference', 'date': 'Oct 23, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Zymfentra \n(infliximab-dyyb) for the maintenance treatment of adults with moderately \nto severely active...', 'thumbnail': 'https://serpapi.com/searches/672460fa1397ba2adff58fb9/images/c82d318307dd825a3df1af00b5d725b52cc0320196ab4c0b436e1c39d89bb307.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.762981116771698}",,,,,,,,,,['neutral'],neutral,1 NCT00330330,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S0753332222010988', 'title': 'Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders', 'source': 'ScienceDirect.com', 'date': 'Sep 20, 2022', 'snippet': 'PTP1B is involved in several pathophysiological mechanisms affecting \nneurons. PTP1B inhibition decreases neuroinflammation, insulin resistance \nand reticulum...', 'thumbnail': 'https://serpapi.com/searches/672460fd69012193a5fee478/images/a27ef4fa8c8181f6022570e949caef60d9ac9a3636139b8c7280182f48bd78c2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7960569262504578}",,,,,,,,,,['neutral'],neutral,1 NCT03635489,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-020-0199-6', 'title': 'Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence', 'source': 'Nature', 'date': 'Jul 29, 2020', 'snippet': 'Advanced and recurrent gynecological cancers are associated with poor \nprognosis and lack of effective treatment. The developments of the...', 'thumbnail': 'https://serpapi.com/searches/6724613aa25104e3b9e6fd7d/images/5ecd2ceae29be190e2839aab120dc61f7bd40633cd51233ad2c3395a9d5a39c4.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6648945212364197}",,,,,,,,,,['neutral'],neutral,1 NCT02279745,"{'position': 1, 'link': 'https://www.pulmonologyadvisor.com/news/long-term-safety-and-tolerability-of-ralinepag-in-pah/', 'title': 'Long-Term Safety, Tolerability of Ralinepag in Pulmonary Arterial Hypertension', 'source': 'Pulmonology Advisor', 'date': 'May 31, 2022', 'snippet': 'An open-label extension study of the long-term safety of ralinepag for PAH \nfound a positive risk-benefit ratio similar to that of the parent...', 'thumbnail': 'https://serpapi.com/searches/6724613b9872179945fc4be3/images/4e690663fc6e2e98ce455b6eb78242425201e3e25821aa691692ef9bcc83d429.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8393498659133911}",,,,,,,,,,['neutral'],neutral,1 NCT01757808,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/circresaha.115.303827', 'title': 'Current Clinical Management of Pulmonary Arterial Hypertension', 'source': 'American Heart Association Journals', 'date': 'Jun 20, 2014', 'snippet': 'In this article, we discuss the clinical approach and management of PAH \nfrom the perspective of a single US-based academic institution.', 'thumbnail': 'https://serpapi.com/searches/6724618ef410441876f50dd2/images/6f3a88a8a7ca4c209934e36901273202b0682bfe7c004e883cd80a0380012690.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9431232810020447}",,,,,,,,,,['neutral'],neutral,1 NCT00095654,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa065061', 'title': 'Effect of Ramipril on the Incidence of Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'May 1, 2018', 'snippet': 'Previous studies have suggested that blockade of the renin–angiotensin \nsystem may prevent diabetes in people with cardiovascular disease or \nhypertension.', 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response in the HAWK and HARRIER trials using deep learning in retinal fluid volume and compartment analysis | Eye', 'source': 'Nature', 'date': 'May 6, 2022', 'snippet': 'To assess the therapeutic response to brolucizumab and aflibercept by deep \nlearning/OCT-based analysis of macular fluid volumes in neovascular \nage-related...', 'thumbnail': 'https://serpapi.com/searches/672462a92fab62d9c7da4094/images/e4f88c0e6985293b7d78772d7914ae25e45e57bf78f27e07434f970e8b9dbe45.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.895088255405426}",,,,,,,,,,['neutral'],neutral,1 NCT05032196,"{'position': 1, 'link': 'https://huntingtonsdiseasenews.com/news/wve-003-safely-lowers-mutant-huntingtin-protein-trial/', 'title': 'WVE-003 Safely Lowers Mutant Huntingtin Protein in Phase 1/2 Trial', 'source': ""Huntington's Disease News"", 'date': 'Oct 11, 2022', 'snippet': ""The Wave therapy candidate WVE-003 safely lowered levels of the mutant \nhuntingtin protein in Huntington's disease patients, trial data show."", 'thumbnail': 'https://serpapi.com/searches/6724619a96a329686adfcee3/images/ea510b30aeb26687b0196a0a7a16584b4a12c3619c745704c82bf96236f5df7d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8356421589851379}","{'position': 2, 'link': 'https://www.globenewswire.com/news-release/2022/09/20/2519092/0/en/Wave-Life-Sciences-Announces-Positive-Update-from-Phase-1b-2a-SELECT-HD-Trial-with-Initial-Results-Indicating-Allele-Selective-Target-Engagement-with-WVE-003-in-Huntington-s-Diseas.html', 'title': 'Wave Life Sciences Announces Positive Update from Phase', 'source': 'GlobeNewswire', 'date': 'Sep 20, 2022', 'snippet': 'Single doses of WVE-003 appear generally safe and well-tolerated CSF mutant \nhuntingtin (mHTT) protein was reduced following single doses of...', 'thumbnail': 'https://serpapi.com/searches/6724619a96a329686adfcee3/images/ea510b30aeb2668794891c885e223727bee101252d0df3fbfb28f8538aeaec74.png', 'sentiment': 'positive', 'sentiment_prob': 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2018', 'snippet': 'Learn more about how Charlotte and Gwyneth Gray were treated in a clinical \ntrial for their form of Batten disease. Clinical trials often are...', 'thumbnail': 'https://serpapi.com/searches/672461aa98fad6bca024606b/images/b3e48213a4d342c96f242db1a9625d253e0b594b9ee2a6b14d4b902eaef0f378.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8681191802024841}",,,,,,,,,,['neutral'],neutral,1 NCT03430479,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-022-27048-3', 'title': 'Phase Ib/II study of nivolumab combined with palliative radiation therapy for bone metastasis in patients with HER2-negative metastatic breast cancer | Scientific Reports', 'source': 'Nature', 'date': 'Dec 27, 2022', 'snippet': 'This phase I/II study investigated the efficacy and safety of nivolumab \nplus RT in HER2-negative metastatic breast cancer requiring palliative RT \nfor bone...', 'thumbnail': 'https://serpapi.com/searches/672461fb9f8bfc8b73899d6d/images/eb8ec4690beba31968c9c50448a06a749f67521899561f19f09e9ff2bc7f0db2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.892707109451294}",,,,,,,,,,['neutral'],neutral,1 NCT01896271,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/home/cancer-topics/general-oncology/radio-immunotherapy-combination-may-be-effective-on-specific-tumor-types/', 'title': 'Radio/Immunotherapy Combination May Be Effective on Specific Tumor Types', 'source': 'Cancer Therapy Advisor', 'date': 'Jul 11, 2016', 'snippet': 'A combination of radiotherapy with local and systemic immunotherapy may be \nclinically beneficial for treating some types of tumors.', 'thumbnail': 'https://serpapi.com/searches/6724620429e6fbc169a86d80/images/3c689e2158e8de1bb9db60223d2fc8a1e2eedff337a68333c31b82911f8f81da.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5377838611602783}",,,,,,,,,,['neutral'],neutral,1 NCT04442295,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/stoke-therapeutics-clinical-hold-released/', 'title': 'Stoke Therapeutics eyes Phase III Dravet syndrome trial, as FDA releases hold', 'source': 'Clinical Trials Arena', 'date': 'Aug 8, 2024', 'snippet': 'Stoke Therapeutics has revealed it will move to Phase III trials of its \nDravet syndrome drug zorevunersen after the US Food and Drug Administration \n(FDA)...', 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e8aee3db71f47df1cbb3741c64a636528c246e48947bbeff1b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.917353630065918}","{'position': 2, 'link': 'https://dravetsyndromenews.com/news/stk-001-trials-update-benefits-seizures-cognition-behavior/', 'title': 'STK-001 still showing potential as Dravet syndrome treatment |...', 'source': 'Dravet Syndrome News', 'date': 'Aug 1, 2023', 'snippet': 'STK-001 can reduce seizure frequency and aid cognition and behavior in \nyoung Dravet syndrome, new data from Phase 1/2 clinical trials show.', 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e8f6f4ef56c2e944af5f8d7ea20e78e10bed81fa33d080acff.png', 'sentiment': 'positive', 'sentiment_prob': 0.6383975148200989}","{'position': 3, 'link': 'https://dravetsyndromenews.com/news/stoke-phase-3-trial-stk-001-planned-next-year-phase-1-2a-data/', 'title': ""Stoke's Phase 3 Trial of STK-001 for Dravet Planned for Next Year..."", 'source': 'Dravet Syndrome News', 'date': 'Jan 10, 2023', 'snippet': ""New safety and efficacy data from two Phase 1/2a clinical trials testing \nSTK-001, Stoke Therapeutics' investigational treatment for children and \nadolescents..."", 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e88a6027e9d22c005145c8286bccfc09aabcbf41dc93e67954.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8406557440757751}","{'position': 4, 'link': 'https://dravetsyndromenews.com/news/stk-001-lowers-seizures-aids-cognition-behavior-trials/', 'title': 'STK-001 lowers seizures, aids cognition and behavior in clinical trials', 'source': 'Dravet Syndrome News', 'date': 'Dec 5, 2023', 'snippet': 'An update on open-label studies in young Dravet patients finds STK-001 \nmarkedly reduces seizure frequency, improves cognition and behavior.', 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e8e0721d9912e0d8b6335a3e30bd2f381d213b1e1d27f50aa7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8194456100463867}","{'position': 5, 'link': 'https://dravetsyndromenews.com/news/fda-allows-testing-stk-001-high-dose-monarch-trial/', 'title': 'FDA allows testing of STK-001 at single high dose in MONARCH trial...', 'source': 'Dravet Syndrome News', 'date': 'Mar 21, 2023', 'snippet': 'A 70 mg single dose of STK-001 is being added to the MONARCH trial in \nchildren with Dravet; multiple high dosing is part of ongoing UK...', 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e81d9b3b404ee5cc1c90f968568513082a0d10b87f02886ccf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8700740337371826}","{'position': 6, 'link': 'https://dravetsyndromenews.com/news/stokes-tango-boosts-dravet-protein-in-mice-brains-study-finds/', 'title': 'Stoke’s TANGO Found to Boost Dravet Protein in Mice Brains', 'source': 'Dravet Syndrome News', 'date': 'Jan 26, 2021', 'snippet': ""Stoke Therapeutics' TANGO antisense oligonucleotide-based technology \nboosted NaV1.1 protein – lacking in Dravet patients – in mice brains."", 'thumbnail': 'https://serpapi.com/searches/67246209f963e73c2b2ed7c0/images/06039b51a2ca26e85dd0560f28b45c7b249214c6dfb0c5c2bbcc84584c3bd8e2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8645341992378235}",,,,,"['neutral', 'positive', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03157037,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/hansa-biopharma-imlifidase/', 'title': 'Hansa starts dosing in Phase III trial in anti-GBM disease', 'source': 'Clinical Trials Arena', 'date': 'May 30, 2023', 'snippet': 'The global Phase III trial will evaluate the renal function of patients \nwith a rare autoimmune condition that receive imlifidase and SoC.', 'thumbnail': 'https://serpapi.com/searches/672462291fc7c565347ded9a/images/9a886a47c366b0e0bdf343a49c0af694b80039663dbb4b60701b7556fe6a715b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9224563837051392}",,,,,,,,,,['neutral'],neutral,1 NCT01839487,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2022.1020888/full', 'title': 'Culprits of PDAC resistance to gemcitabine and immune checkpoint inhibitor: Tumour microenvironment components', 'source': 'Frontiers', 'date': 'Oct 9, 2022', 'snippet': 'In our review, we shed light on how crosstalk of complex environmental \ncomponents modulates PDAC drug resistance, and we summarize related \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/6724624c64f11d5673dd9ae1/images/71796ceb37d8c963b7e9b865a81b9f37aaf760350347a60bc592c0b34f295540.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8721804618835449}",,,,,,,,,,['neutral'],neutral,1 NCT03233776,"{'position': 1, 'link': 'https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04847-5', 'title': 'Anakinra: efficacy in the management of fever during neutropenia and mucositis in autologous stem cell transplantation (AFFECT-2)—study protocol for a multicenter randomized double-blind placebo-controlled trial', 'source': 'BioMed Central', 'date': 'Nov 23, 2020', 'snippet': 'The aim of the AFFECT-2 study is to determine the efficacy of anakinra in \npreventing fever during neutropenia (FN) and mucositis in this study \npopulation.', 'thumbnail': 'https://serpapi.com/searches/672462cf20e6eb1dbbbe32c2/images/01a9c861aafb2d7b9ef982e2c5dcbfa90ed3101a01a6ca7f688e78566174cc8a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8506823182106018}",,,,,,,,,,['neutral'],neutral,1 NCT03274804,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-37872-4', 'title': 'CAR-neutrophil mediated delivery of tumor-microenvironment responsive nanodrugs for glioblastoma chemo-immunotherapy', 'source': 'Nature', 'date': 'Apr 20, 2023', 'snippet': 'This biomimetic CAR-neutrophil drug delivery system is a safe, potent and \nversatile platform for treating GBM and possibly other devastating diseases.', 'thumbnail': 'https://serpapi.com/searches/672464fce6862b708a062a86/images/4583a564ccc52542479e3971a729574523e0a1a23fa612dc597d8a21247c51d6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7221992015838623}",,,,,,,,,,['neutral'],neutral,1 NCT05463744,"{'position': 1, 'link': 'https://www.researchgate.net/publication/380177828_Once-weekly_insulins_a_promising_approach_to_reduce_the_treatment_burden_in_people_with_diabetes', 'title': '(PDF) Once-weekly insulins: a promising approach to reduce the treatment burden in people with diabetes', 'source': 'ResearchGate', 'date': 'Aug 30, 2024', 'snippet': 'PDF | Despite the availability of new classes of glucose-lowering drugs \nthat improve glycaemic levels and minimise long-term complications,...', 'thumbnail': 'https://serpapi.com/searches/6724650aa5e50212a2fc23de/images/39014b7eb8f104f0e0ac2bca5a7a6416b7c76003aaf864aaa40d148ece72b09f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5478062033653259}",,,,,,,,,,['neutral'],neutral,1 NCT05425732,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-21-valent-pneumococcal-conjugate-vaccine-capvaxive/', 'title': 'FDA Approves 21-Valent Pneumococcal Conjugate Vaccine Capvaxive', 'source': 'Medical Professionals Reference', 'date': 'Jun 18, 2024', 'snippet': 'The Food and Drug Administration (FDA) has approved Capvaxive™ (V116; 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Una revisión exhaustiva de 87 \nprogramas clínicos de tratamientos para la retina.', 'thumbnail': 'https://serpapi.com/searches/672462e614c31e1ae795a990/images/4e702172ba9e1fe03fe37916b94341b256aea10606399ea800d36d9cafe24f0c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9071215987205505}",,,,,,,,,,['neutral'],neutral,1 NCT00421213,"{'position': 1, 'link': 'https://lymphomanewstoday.com/2019/10/22/phase-2-trial-darinaparsin-ptcl-reaches-complete-patient-enrollment/', 'title': 'Phase 2 Trial Testing Darinaparsin Completes Enrollment of Asian Patients with Relapsed or Refractory PTCL', 'source': 'Lymphoma News Today', 'date': 'Oct 22, 2019', 'snippet': ""A Phase 2 clinical trial assessing Solasia Pharma's lead candidate \ndarinaparsin as a treatment for relapsed or refractory peripheral T-cell..."", 'thumbnail': 'https://serpapi.com/searches/672462e9207c88d3232df4e0/images/357729ab5cbfdebd67f50116da322bae417ba35f4f41f15bff6b41eee282a740.jpeg', 'sentiment': 'neutral', 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clinical activity in \npatients with MSI-H and/or dMMR mCRC after progression on standard \nchemotherapy.', 'thumbnail': 'https://serpapi.com/searches/6724630d671f3fada070da7b/images/64b152b8a21bb40a23a1f09fe8e74c328d0bfc76329fe56518ef59392bc0848d.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5896679759025574}","{'position': 3, 'link': 'https://immuno-oncologynews.com/2020/07/01/fda-approves-keytruda-first-line-therapy-certain-advanced-colorectal-cancers/', 'title': 'FDA Approves Keytruda as First-line Therapy for Certain Advanced Colorectal Cancers', 'source': 'Immuno-Oncology News', 'date': 'Jul 1, 2020', 'snippet': 'The U.S. Food and Drug Administration (FDA) has approved Keytruda \n(pembrolizumab) as a first-line therapy for people with inoperable or...', 'thumbnail': 'https://serpapi.com/searches/6724630d671f3fada070da7b/images/64b152b8a21bb40af7e66a7f34ceb7e49344e2604e41eff523aae16f2fc98d75.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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results', 'source': 'Cystic Fibrosis News Today', 'date': 'Jan 10, 2024', 'snippet': 'Results of three global clinical trials of a new triple-combination CFTR \nmodulator therapy for cystic fibrosis (CF) — vanzacaftor, tezacaftor...', 'thumbnail': 'https://serpapi.com/searches/672463657ebde5567687a12e/images/81ff9926e46d0b5fc70d00c724875953713a1854e2c5592abb0574c2fde91b23.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8913163542747498}",,,,,,,,,,['neutral'],neutral,1 NCT01818492,"{'position': 1, 'link': 'https://www.biospace.com/fda-approves-gamifant-emapalumab-lzsg-the-first-and-only-treatment-indicated-for-primary-hemophagocytic-lymphohistiocytosis-hlh', 'title': 'FDA Approves Gamifant® (emapalumab-lzsg), the First and Only Treatment Indicated for Primary Hemophagocytic Lymphohistiocytosis (HLH)', 'source': 'BioSpace', 'date': 'Nov 20, 2018', 'snippet': 'The US Food and Drug Administration (FDA) has approved Gamifant \n(emapalumab-lzsg), an interferon gamma (IFNγ) blocking antibody for the \ntreatment of pediatric...', 'thumbnail': 'https://serpapi.com/searches/67246373f6aa53974ffe6f1a/images/6ad2e847d5d4b062a20af43f8f4e9b49227260aa17af604aaa58ee9e97b0c8e2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5843455791473389}",,,,,,,,,,['neutral'],neutral,1 NCT01803867,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/rhigm22-multiple-sclerosis/', 'title': 'rHIgM22 for Multiple Sclerosis', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 23, 2019', 'snippet': 'rHIgM22 is an investigational remyelinating antibody being developed by \nAcorda Therapeutics in collaboration with the Mayo Foundation for Medical \nEducation...', 'thumbnail': 'https://serpapi.com/searches/67246396f9f904fdc2c98332/images/893b5138f14f64ec8e28f535672cc46d6a1cb2ecd77c6f508150336410aba653.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9288907647132874}",,,,,,,,,,['neutral'],neutral,1 NCT02008357,"{'position': 1, 'link': 'https://keck.usc.edu/news/data-from-largest-clinical-trial-of-pre-symptomatic-alzheimers-disease-now-widely-available/', 'title': 'Data from largest clinical trial of pre-symptomatic Alzheimer’s disease now widely available', 'source': 'Keck School of Medicine of USC', 'date': 'Jul 23, 2024', 'snippet': 'Researchers from the Keck School of Medicine of USC, who conducted the \nfirst and largest phase 3 clinical trial of pre-symptomatic...', 'thumbnail': 'https://serpapi.com/searches/672463a4d364b43b71ad04c4/images/f9bf738f0644fa6df6837c7aca6f10a20044174a0bc86adc4ff747253577bddc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9137422442436218}","{'position': 2, 'link': 'https://www.nia.nih.gov/news/alzheimers-trial-screening-data-links-high-amyloid-levels-early-stage-disease', 'title': ""Alzheimer's trial screening data links high amyloid levels with early stage disease"", 'source': 'National Institute on Aging (.gov)', 'date': 'Apr 6, 2020', 'snippet': 'The first paper from the NIH-funded A4 study supports the hypothesis that \nhigher levels of amyloid protein in the brain represent an early...', 'thumbnail': 'https://serpapi.com/searches/672463a4d364b43b71ad04c4/images/f9bf738f0644fa6de8a3f3fd5e21911657a7cb36e867084b12d687954fb40bb1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9027205109596252}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02344004,"{'position': 1, 'link': 'https://bronchiectasisnewstoday.com/2020/10/30/arikayce-approved-europe-for-mac-lung-infections-non-cf-adults/', 'title': 'Arikayce Approved in Europe for MAC Lung Infections in Non-CF Adults', 'source': 'Bronchiectasis News Today', 'date': 'Oct 30, 2020', 'snippet': 'The European Commission has approved Arikayce as a treatment for lung \ninfections caused by MAC bacteria in adults without cystic fibrosis.', 'thumbnail': 'https://serpapi.com/searches/672463a50f2a2c7159533100/images/03cedbd90b70e6fd18f63e7ccbe2a6bfeba54dc8d388afa7070fff30d9ba0464.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7679176926612854}",,,,,,,,,,['neutral'],neutral,1 NCT02953665,"{'position': 1, 'link': 'https://www.nature.com/articles/s41380-022-01792-4', 'title': 'Incretin and insulin signaling as novel therapeutic targets for Alzheimer’s and Parkinson’s disease', 'source': 'Nature', 'date': 'Oct 18, 2022', 'snippet': 'Incretin mimetics may act through the restoration of insulin signaling \npathways, inducing further neuroprotective effects.', 'thumbnail': 'https://serpapi.com/searches/672463f0861b9da4bf287ae0/images/887bc0432230a41258becd1d7171b581596c815571ab5f4b594dfc99fc75915a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8566185832023621}",,,,,,,,,,['neutral'],neutral,1 NCT00623740,"{'position': 1, 'link': 'https://www.nature.com/articles/s41390-024-03601-w', 'title': 'Bronchopulmonary dysplasia to predict neurodevelopmental impairment in infants born extremely preterm', 'source': 'Nature', 'date': '1 week ago', 'snippet': 'Bronchopulmonary dysplasia (BPD) in extremely low gestational age neonates \n(ELGANs) was associated with neurodevelopmental impairment (NDI).', 'thumbnail': 'https://serpapi.com/searches/67246403361fd472bcccae88/images/6918bf41613f8e03181f1f53d6776b2977d1e06b4b851cfc70ada24c9d0bd6bf.png', 'sentiment': 'negative', 'sentiment_prob': 0.6061035990715027}","{'position': 2, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/dmcn.15470', 'title': 'Neurocognitive outcomes at age 5 years after prophylactic hydrocortisone in infants born extremely preterm', 'source': 'Wiley Online Library', 'date': 'Nov 23, 2022', 'snippet': 'Hydrocortisone treatment was significantly associated with a greater chance \nto survive at 5 years of age with a full-scale IQ equal to or greater than \n90...', 'thumbnail': 'https://serpapi.com/searches/67246403361fd472bcccae88/images/6918bf41613f8e038d17a96f625367a80f066d157194a1aa85bac4b7d0887f81.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7614339590072632}","{'position': 3, 'link': 'https://www.nature.com/articles/s41390-023-02785-x', 'title': 'The beneficial effect of prophylactic hydrocortisone treatment in extremely preterm infants improves upon adjustment of the baseline characteristics', 'source': 'Nature', 'date': 'Aug 31, 2023', 'snippet': 'Prophylactic low-dose hydrocortisone (HC) was found to improve survival \nwithout bronchopulmonary dysplasia (BPD) in extremely preterm...', 'thumbnail': 'https://serpapi.com/searches/67246403361fd472bcccae88/images/6918bf41613f8e0325e09bc9ef669be6dd4d5ada6ea91bb4aa8e29b383827d70.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6055935621261597}",,,,,,,,"['negative', 'neutral', 'positive']",negative,0 NCT02464033,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.624568/full', 'title': 'Evolving Antibody Therapies for the Treatment of Type 1 Diabetes', 'source': 'Frontiers', 'date': 'Feb 6, 2024', 'snippet': 'Type 1 diabetes (T1D) is widely considered to be a T cell driven autoimmune \ndisease resulting in reduced insulin production due to \ndysfunction/destruction...', 'thumbnail': 'https://serpapi.com/searches/672465cd5ed3ca94b4679a60/images/ae686c97bb4ef7c3d39f57766a9a478bbf7a30b5c784b4b110a82a9104e216a6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5459937453269958}",,,,,,,,,,['neutral'],neutral,1 NCT03041363,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-30578-z', 'title': 'Maximum dose, safety, tolerability and ketonemia after triheptanoin in glucose transporter type 1 deficiency (G1D)', 'source': 'Nature', 'date': 'Mar 1, 2023', 'snippet': 'Augmentation of anaplerosis, or replenishment of carbon lost during \nintermediary metabolic transitions, is desirable in energy metabolism...', 'thumbnail': 'https://serpapi.com/searches/672465e5707fd3a645c49fd5/images/3e2d27effb0a2a9cc3ad30cc920970020000bc5feae2874a02051256cdc00413.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7260956764221191}",,,,,,,,,,['neutral'],neutral,1 NCT04830397,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/oncology-acute-pharyngitis-clinical-trials/', 'title': 'Pipeline Moves: Premature Phase II end of cancer, acute pharyngitis clinical trials leads to advancement shot drop', 'source': 'Clinical Trials Arena', 'date': '17 May 2022', 'snippet': 'The Clinical Trials Arena team also reviews three separate early-phase \ntrial completions in type 2 diabetes, ophthalmic issues, and cancer.', 'thumbnail': 'https://serpapi.com/searches/672465f456f970aa14165782/images/095f860d6b97cde35253c8987d6e073bf2fadf66078e1f00c0871290150f0db6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.826110303401947}",,,,,,,,,,['neutral'],neutral,1 NCT04658186,"{'position': 1, 'link': 'https://www.nature.com/articles/s41531-023-00552-7', 'title': 'In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson’s disease', 'source': 'Nature', 'date': 'Jul 17, 2023', 'snippet': ""Direct targeting of alpha-synuclein (ASYN) has emerged as a \ndisease-modifying strategy for Parkinson's disease and other \nsynucleinopathies..."", 'thumbnail': 'https://serpapi.com/searches/672467401a5b548bf79a89cd/images/0faa4602b735309eb68d66963797d9b75153faaf4fbad100b889442df2e0e745.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8450441360473633}","{'position': 2, 'link': 'https://parkinsonsnewstoday.com/news/mice-ucb0599-parkinsons-lowers-inflammation-improves-coordination/', 'title': 'UCB0599 reduces inflammation, improves coordination in mice', 'source': ""Parkinson's News Today"", 'date': 'Aug 4, 2023', 'snippet': 'The experimental oral therapy UCB0599 — now in clinical trials — improves \nmotor coordination and reduces inflammation and levels of the...', 'thumbnail': 'https://serpapi.com/searches/672467401a5b548bf79a89cd/images/0faa4602b735309e047eebb87c1cd90503518e4f09c70665f93f4100b90bbdeb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6931576728820801}","{'position': 3, 'link': 'https://www.apdaparkinson.org/article/american-academy-of-neurology-2021/', 'title': 'Highlights from the 2021 AAN Annual Meeting', 'source': 'American Parkinson Disease Association', 'date': 'Apr 27, 2021', 'snippet': ""Dr. Gilbert reviews the latest updates in Parkinson's research from the \n2021 American Academy of Neurology Annual Meeting."", 'thumbnail': 'https://serpapi.com/searches/672467401a5b548bf79a89cd/images/0faa4602b735309e6be532bc7555ebbe87049ab85f5f5b829bfe196d2e68bdc4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.791485607624054}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02032277,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/os-and-efs-improved-with-neoadjuvant-chemotherapy-carboplatin-for-locally-advanced-tnbc', 'title': 'OS and EFS Improved With Neoadjuvant Chemotherapy/Carboplatin for Locally Advanced TNBC', 'source': 'Cancer Network', 'date': 'Dec 10, 2022', 'snippet': 'Patients with operable, locally advanced triple-negative breast cancer \nexperienced notable improvements in survival following treatment with...', 'thumbnail': 'https://serpapi.com/searches/672466d013e5d89c18174b81/images/80e42b6c623d130eee01b49a940efaf31b2b4829d1c74380be63f8849f902612.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5052809119224548}",,,,,,,,,,['positive'],positive,1 NCT05667779,"{'position': 1, 'link': 'https://alsnewstoday.com/news/first-healthy-volunteers-dosed-mad-study-testing-als-therapy-qrl-101/', 'title': 'First group of healthy volunteers dosed in QRL-101 MAD study', 'source': 'ALS News Today', 'date': '1 month ago', 'snippet': 'The Phase 1 clinical trial is expected to enroll about 60 participants to \ntest how safe and well tolerated multiple doses of QRL-101 are.', 'thumbnail': 'https://serpapi.com/searches/672466f41b4e346ca366c64b/images/bff8c67cbed7b4472c703b9bb95dacbb97ff4082935aafd644cf6f6520a35d01.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7422958612442017}","{'position': 2, 'link': 'https://alsnewstoday.com/news/first-participants-dosed-phase-1-trial-als-therapy-qrl-101/', 'title': 'Dosing Starts in First-in-human Phase 1 Trial of QRL-101 for ALS', 'source': 'ALS News Today', 'date': 'Jan 11, 2023', 'snippet': 'A Phase 1 clinical trial has begun dosing healthy volunteers to investigate \nQRL-101, an oral treatment candidate for ALS.', 'thumbnail': 'https://serpapi.com/searches/672466f41b4e346ca366c64b/images/bff8c67cbed7b44728bc0c09111ffd0b43e9fa1fc3a5a5762e72f5bb54d43069.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9149633049964905}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04777201,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-52942-3', 'title': 'Efficacy and safety of intravitreal faricimab for neovascular age-related macular degeneration: a systematic review and meta-analysis | Scientific Reports', 'source': 'Nature', 'date': 'Jan 30, 2024', 'snippet': 'We conducted a systematic review and meta-analysis to evaluate the visual, \nanatomical, and safety outcomes of the intravitreal faricimab,...', 'thumbnail': 'https://serpapi.com/searches/67246722f7adbf72b3a17a62/images/8dfad76682d55f79d6920b31b2a9f4bd5e2f41e6492d4c49ed648b6922931b32.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8612781763076782}","{'position': 2, 'link': 'https://www.globenewswire.com/news-release/2024/07/30/2920702/0/en/European-Commission-approves-Roche-s-Vabysmo-for-treatment-of-retinal-vein-occlusion-RVO.html', 'title': 'European Commission approves Roche’s Vabysmo for treatment of retinal vein occlusion (RVO)', 'source': 'GlobeNewswire', 'date': 'Jul 30, 2024', 'snippet': 'Approval is based on data from two Phase III studies in branch and central \nretinal vein occlusion (RVO) showing early and sustained vision...', 'thumbnail': 'https://serpapi.com/searches/67246722f7adbf72b3a17a62/images/8dfad76682d55f79737d26c4b4a8092885828c7d7d153759eecbc6e0925e08c5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6009171605110168}","{'position': 3, 'link': 'https://www.stocktitan.net/news/RHHBY/roche-s-vabysmo-improved-vision-in-underrepresented-populations-with-y3hygys486ou.html', 'title': 'Roche’s Vabysmo improved vision in underrepresented populations with diabetic macular edema (DME) in a first-of-its-kind study', 'source': 'Stock Titan', 'date': '2 weeks ago', 'snippet': 'Roche announced positive one-year results from the ELEVATUM study, \nevaluating Vabysmo® (faricimab) for diabetic macular edema (DME) in...', 'thumbnail': 'https://serpapi.com/searches/67246722f7adbf72b3a17a62/images/8dfad76682d55f7999efbff0664e08bb07ed5af18c5b9eccd76e3218533aa779.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7804692983627319}","{'position': 4, 'link': 'https://www.globenewswire.com/de/news-release/2024/07/17/2914761/0/en/Roche-s-Vabysmo-showed-extended-durability-continued-efficacy-and-a-consistent-safety-profile-in-long-term-diabetic-macular-edema-DME-study.html', 'title': 'Roche’s Vabysmo showed extended durability, continued', 'source': 'GlobeNewswire', 'date': 'Jul 17, 2024', 'snippet': 'More than 90% of patients had absence of DME after four years in a \npre-specified exploratory endpointPeople treated with Vabysmo sustained...', 'thumbnail': 'https://serpapi.com/searches/67246722f7adbf72b3a17a62/images/8dfad76682d55f7974b92db3d4d1a88ea668846e6267fb5d506b0424b956096f.png', 'sentiment': 'positive', 'sentiment_prob': 0.5305542945861816}",,,,,,,"['neutral', 'neutral', 'positive', 'positive']",neutral,1 NCT03249103,"{'position': 1, 'link': 'https://fibromyalgianewstoday.com/2019/10/30/non-opioid-therapy-nyx-2925-shows-potential-treat-fibromyalgia-blocks-pain-processing-biomarkers/', 'title': 'NYX-2925 Non-Opioid Therapy Shows Potential to Treat Fibromyalgia, Study Shows', 'source': 'Fibromyalgia News Today', 'date': 'Oct 30, 2019', 'snippet': 'Treatment with the new, non-opioid therapy NYX-2925 can block \nhypersensitivity to pain in patients with fibromyalgia, results from a...', 'thumbnail': 'https://serpapi.com/searches/67246733c76a222c5beb883c/images/c42bad2f47dd0d78a97d779aac50c3be5876b3c85ca20a9e2490864b9d5724b3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6133267879486084}",,,,,,,,,,['neutral'],neutral,1 NCT03361865,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2018.00423/full', 'title': 'Updates in the Clinical Development of Epacadostat and Other Indoleamine 2,3-Dioxygenase 1 Inhibitors (IDO1) for Human Cancers', 'source': 'Frontiers', 'date': 'Oct 3, 2018', 'snippet': 'This minireview will primarily focus on recent clinical research of \nEpacadostat (E) and other IDO1 inhibitors and discuss available data and \nfuture...', 'thumbnail': 'https://serpapi.com/searches/6724663c52a04e033204445c/images/3f8b3ffd347359221de5f73bf33a2ce508c16c515c2b3e28379fa65c622d5783.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9207820296287537}",,,,,,,,,,['neutral'],neutral,1 NCT03533114,"{'position': 1, 'link': 'https://www.psychiatryadvisor.com/news/idiopathic-hypersomnia-treated-with-lxb-weight-loss-equal-to-or-greater-than-5-is-common-in-more-than-25-of-patients/', 'title': 'Weight Changes with Lower-Sodium Oxybate in Idiopathic Hypersomnia', 'source': 'Psychiatry Advisor', 'date': 'Jun 6, 2022', 'snippet': 'Adults with idiopathic hypersomnia treated with LXB, weight loss equal to \nor greater than 5% is common in more than 25% of patients.', 'thumbnail': 'https://serpapi.com/searches/6724663d2fab62d9c7da41a8/images/b364fa305adf50ffb68b4cd1f6a663d8f3a15a9912850d0c21c4a9220b0d56c0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7807514667510986}",,,,,,,,,,['neutral'],neutral,1 NCT02752074,"{'position': 1, 'link': 'https://www.genengnews.com/news/incyte-merck-co-halt-phase-iii-trial-after-epacadostat-keytruda-combination-fails-in-melanoma/', 'title': 'Incyte, Merck & Co. Halt Phase III Trial After Epacadostat/Keytruda Combination Fails in Melanoma', 'source': 'Genetic Engineering and Biotechnology News', 'date': 'Apr 6, 2018', 'snippet': ""A Phase III trial assessing the combination of Incyte's lead cancer \nimmunotherapy candidate epacadostat (INCB024360) and Merck & Co."", 'thumbnail': 'https://serpapi.com/searches/6724665f1f3d4bc2ce222446/images/6dba32f5a7ceeb94687cd054486a659e13f139b204d62c3c9189f924ebc911c0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5240946412086487}",,,,,,,,,,['neutral'],neutral,1 NCT03594110,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2204233', 'title': 'Empagliflozin in Patients with Chronic Kidney Disease', 'source': 'The New England Journal of Medicine', 'date': 'Nov 4, 2022', 'snippet': 'The effects of empagliflozin in patients with chronic kidney disease who \nare at risk for disease progression are not well understood. The \nEMPA-KIDNEY trial...', 'thumbnail': 'https://serpapi.com/searches/6724669b7a12fda58f0b6304/images/d1622d540791aeafe4b05c3a7e87df7ca652e0dd0206d8e61c2697d08206a0c4.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.5813755393028259}","{'position': 2, 'link': 'https://www.thelancet.com/journals/landia/article/PIIS2213-8587(23)00322-4/fulltext', 'title': 'Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial', 'source': 'The Lancet', 'date': 'Dec 4, 2023', 'snippet': 'The EMPA-KIDNEY trial showed that empagliflozin reduced the risk of the \nprimary composite outcome of kidney disease progression or cardiovascular \ndeath in...', 'thumbnail': 'https://serpapi.com/searches/6724669b7a12fda58f0b6304/images/d1622d540791aeafbb9a1003d0c72e6c48cb75fbf74ad9dd64d1ea9c0d58defb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8561785817146301}","{'position': 3, 'link': 'https://www.drugtopics.com/view/fda-approves-empagliflozin-for-use-in-ckd', 'title': 'FDA Approves Empagliflozin for Use in CKD', 'source': 'Drug Topics', 'date': 'Sep 22, 2023', 'snippet': 'This is the fourth approval for the drug stemming from the EMPOWER clinical \ntrial program.', 'thumbnail': 'https://serpapi.com/searches/6724669b7a12fda58f0b6304/images/d1622d540791aeaf510b3032fef5a24ca657e90e8476153c14ab6dd5f084a08a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6430405974388123}",,,,,,,,"['negative', 'neutral', 'positive']",negative,0 NCT04033068,"{'position': 1, 'link': 'https://www.nature.com/articles/s41541-022-00464-2', 'title': 'Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract', 'source': 'Nature', 'date': 'Apr 19, 2022', 'snippet': 'Zika virus (ZIKV) can cause devastating effects in the unborn fetus of \npregnant women. 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fails at ISLAND primary goal', 'source': 'Lupus News Today', 'date': 'Mar 2, 2023', 'snippet': 'A middle dose of rezpegaldesleukin, an experimental medicine being \ndeveloped by Nektar Therapeutics, led to clinically meaningful gains in \nmeasures of disease...', 'thumbnail': 'https://serpapi.com/searches/672467c98cf8ae01ba365256/images/a26e19da1269d69ac303edef6caa977d46c5a7a7b202efb98b3e45ad4f98ea93.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7214007377624512}",,,,,,,,,,['neutral'],neutral,1 NCT05842213,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2024/04/24/2868337/0/en/Alvotech-Announces-Topline-Results-from-a-Confirmatory-Clinical-Study-for-AVT05-a-Proposed-Biosimilar-for-Simponi-golimumab.html', 'title': 'Alvotech Announces Topline Results from a Confirmatory', 'source': 'GlobeNewswire', 'date': 'Apr 24, 2024', 'snippet': 'The confirmatory clinical safety and efficacy study for AVT05, biosimilar \ncandidate to Simponi® and Simponi Aria® (golimumab),...', 'thumbnail': 'https://serpapi.com/searches/672467f648c97d44855d28e2/images/4bd51a20672829f14de04bc003265c6c99bc0ad2df7e2f8c192dd31c8d0070da.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7174261212348938}","{'position': 2, 'link': 'https://ankylosingspondylitisnews.com/2023/12/04/in-early-trial-avt05-shows-similar-pharmacological-profile-to-simponi/', 'title': 'In early trial, AVT05 shows similar pharmacological profile to Simponi', 'source': 'Ankylosing Spondylitis News', 'date': 'Dec 4, 2023', 'snippet': ""AVT05, Alvotech's biosimilar candidate to treat ankylosing spondylitis, \nshowed a similar pharmacological profile to Simponi (golimumab)."", 'thumbnail': 'https://serpapi.com/searches/672467f648c97d44855d28e2/images/4bd51a20672829f10d903b8c01a6798434b5dc582331fca0b7f44fbe8f538176.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8694635629653931}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02162303,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.060308', 'title': 'Noninvasive Plaque Imaging to Accelerate Coronary Artery Disease Drug Development | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 28, 2022', 'snippet': 'Coronary artery disease (CAD) remains the leading cause of adult mortality \nglobally. Targeting known modifiable risk factors has had...', 'thumbnail': 'https://serpapi.com/searches/672468035f97781090a129f3/images/9d84263085deb8a61a832c9d782c73cac608586bb34a5ce1b3ead134b1197cd4.png', 'sentiment': 'negative', 'sentiment_prob': 0.6367948055267334}",,,,,,,,,,['negative'],negative,0 NCT05160415,"{'position': 1, 'link': 'https://musculardystrophynews.com/news/edg-5506-helping-preserve-muscles-becker-md-phase-1-trial/', 'title': 'EDG-5506 helping to preserve muscles in Becker MD Phase 1 trial |...', 'source': 'Muscular Dystrophy News', 'date': 'Jun 29, 2023', 'snippet': 'Most men with Becker muscular dystrophy in Phase 1 ARCH trial show stable \nor improved motor function after one year of EDG-5506 treatment.', 'thumbnail': 'https://serpapi.com/searches/6724680bd771bd3d1c3e32fa/images/9d12c5ebb893bf4d1af5d81aebfda7f0ea7c2cac8c75462c0112b79c726021ce.png', 'sentiment': 'positive', 'sentiment_prob': 0.6553616523742676}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20230626317214/en/Edgewise-Therapeutics-Announces-Positive-12-Month-Topline-Results-from-the-ARCH-Open-Label-Study-of-EDG-5506-in-Adults-with-Becker-Muscular-Dystrophy-BMD', 'title': 'Edgewise Therapeutics Announces Positive 12-Month Topline Results from the ARCH Open Label Study of EDG-5506 in Adults with Becker Muscular Dystrophy (BMD)', 'source': 'Business Wire', 'date': 'Jun 26, 2023', 'snippet': 'Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a clinical-stage \nbiopharmaceutical company focused on developing orally bioavailable, \ntargeted,...', 'thumbnail': 'https://serpapi.com/searches/6724680bd771bd3d1c3e32fa/images/9d12c5ebb893bf4d365db8c63df440c174a357612376b3fe8a14e88484e3e030.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5894675850868225}","{'position': 3, 'link': 'https://musculardystrophynews.com/news/2-year-edg-5506-treatment-helps-preserve-motor-function-bmd/', 'title': '2-year EDG-5506 treatment helps preserve motor function in BMD', 'source': 'Muscular Dystrophy News', 'date': 'Apr 18, 2024', 'snippet': 'Oral treatment with EDG-5506 continued to stabilize muscle function after \ntwo years in men with Becker MD taking part in a Phase 1 trial.', 'thumbnail': 'https://serpapi.com/searches/6724680bd771bd3d1c3e32fa/images/9d12c5ebb893bf4df190dfc3f4c715829ae15cd9566f099dd0af39b4b71795ba.png', 'sentiment': 'neutral', 'sentiment_prob': 0.497831255197525}","{'position': 4, 'link': 'https://musculardystrophynews.com/news/edg-5506-treatment-shows-promise-becker-md-clinical-trial/', 'title': 'EDG-5506 Treatment Shows Promise in Becker MD Clinical Trial |...', 'source': 'Muscular Dystrophy News', 'date': 'Oct 20, 2022', 'snippet': 'Experimental treatment EDG-5506 continues to lower Becker MD-associated \nmuscle damage and improve motor function in a Phase 1 clinical...', 'thumbnail': 'https://serpapi.com/searches/6724680bd771bd3d1c3e32fa/images/9d12c5ebb893bf4d85d826bb4e1b1ff503ab52b3b716644ab25afaca3f7e3b54.png', 'sentiment': 'positive', 'sentiment_prob': 0.6245688796043396}","{'position': 5, 'link': 'https://musculardystrophynews.com/news/top-10-muscular-dystrophy-stories-2023/', 'title': 'Top 10 muscular dystrophy stories of 2023', 'source': 'Muscular Dystrophy News', 'date': 'Jan 2, 2024', 'snippet': 'Throughout 2023, Muscular Dystrophy News Today worked diligently to cover \nnew scientific research, treatment developments, and clinical...', 'thumbnail': 'https://serpapi.com/searches/6724680bd771bd3d1c3e32fa/images/9d12c5ebb893bf4dca87f3007d244d28151aafcb82af9e9e590ab4d6e974bcf1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5096873641014099}",,,,,,"['positive', 'neutral', 'neutral', 'positive', 'neutral']",neutral,1 NCT04129164,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-024-03009-3', 'title': 'CD40 ligand antagonist dazodalibep in Sjögren’s disease: a randomized, double-blinded, placebo-controlled, phase 2 trial', 'source': 'Nature', 'date': 'Jun 5, 2024', 'snippet': ""Sjögren's disease (SjD) is a chronic, systemic autoimmune disease with no \napproved disease-modifying therapies. Dazodalibep (DAZ), a novel..."", 'thumbnail': 'https://serpapi.com/searches/672468495235f64ee067fe04/images/74687fc9f40950cecff16a733a340617eaf4fbb31ce40a44036880d684fde546.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7201964259147644}","{'position': 2, 'link': 'https://sjogrenssyndromenews.com/news/dazodalibep-clinical-trial-sjogrens-syndrome-meets-goal/', 'title': ""Dazodalibep Clinical Trial for Sjogren's Syndrome Meets New Goal |..."", 'source': ""Sjogren's Syndrome News"", 'date': 'Jan 20, 2023', 'snippet': ""Dazodalibep significantly eased symptoms in a second group of patients \nenrolled in a clinical trial for Sjogren's syndrome."", 'thumbnail': 'https://serpapi.com/searches/672468495235f64ee067fe04/images/74687fc9f40950cef1af2cf0033b2733848da9c14b6e20faa1f594193f8b3e57.png', 'sentiment': 'positive', 'sentiment_prob': 0.7016016840934753}","{'position': 3, 'link': 'https://sjogrenssyndromenews.com/news/dazodalibep-eases-sjogrens-syndrome-symptoms-phase-2-trial/', 'title': 'Dazodalibep seen to ease Sjögren’s syndrome symptoms in Phase 2 trial', 'source': ""Sjogren's Syndrome News"", 'date': 'Jun 6, 2023', 'snippet': ""Dazodalibep, Horizon's experimental therapy for Sjögren's syndrome, safely \nand effectively eased symptoms in two groups of patients in..."", 'thumbnail': 'https://serpapi.com/searches/672468495235f64ee067fe04/images/74687fc9f40950cef2bb7c56913028b7433ea93e58dd0e8f1a8c69d9221948ff.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6257803440093994}","{'position': 4, 'link': 'https://sjogrenssyndromenews.com/news/dazodalibep-eases-moderate-high-disease-activity-sjogrens-patients/', 'title': 'Dazodalibep Eases Moderate-to-high Disease Activity in Sjögren’s Patients: Trial Data', 'source': ""Sjogren's Syndrome News"", 'date': 'Sep 13, 2022', 'snippet': ""Dazodalibep markedly eased disease activity in Sjögren's syndrome patients \nwho live with moderate-to-high systemic disease activity."", 'thumbnail': 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will be launching a Phase 2 clinical trial to...', 'thumbnail': 'https://serpapi.com/searches/6724689cd0c983b24b1ff907/images/232ba13dac20cf1fac4abec24e9745ed406f14c70a2b9f8c5220eb4ecebc810f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.824338436126709}",,,,,,,,,,['neutral'],neutral,1 NCT01611558,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1292166/full', 'title': 'Limitations and potential of immunotherapy in ovarian cancer', 'source': 'Frontiers', 'date': 'Feb 7, 2024', 'snippet': 'In this perspective, we discuss our view of the current state of some of \nthe combination immunotherapies in the treatment of advanced OC, their \nlimitations,...', 'thumbnail': 'https://serpapi.com/searches/672468a7bb55ffb4294ab331/images/b6f2542301a17495d5fddc8241b94ff488bf52fcbd841f9f9bde1879285e22ee.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8876572847366333}",,,,,,,,,,['neutral'],neutral,1 NCT04064242,"{'position': 1, 'link': 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Show', 'source': 'Multiple Sclerosis News Today', 'date': 'Aug 30, 2022', 'snippet': 'Long-term treatment with Ponvory was found to reduce the rate of relapses \nand prevent brain volume loss in relapsing-remitting MS patients.', 'thumbnail': 'https://serpapi.com/searches/67246ba9fc40bf9c975998ad/images/732b0cf18803627845db4ffd285abad7bf682c5604561c8e39988a01c2640168.png', 'sentiment': 'positive', 'sentiment_prob': 0.6364147067070007}",,,,,,,,,,['positive'],positive,1 NCT05341609,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2208822', 'title': 'VV116 versus Nirmatrelvir–Ritonavir for Oral Treatment of Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Dec 28, 2022', 'snippet': 'VV116 was noninferior to nirmatrelvir–ritonavir with respect to the time to \nsustained clinical recovery, with fewer safety concerns.', 'thumbnail': 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\n・組織学的または細胞学的に診断されたステージIIIB(局所的に進行または再発し、根治療法の...', 'thumbnail': 'https://serpapi.com/searches/67246e0154605c64279507fa/images/a88deb56b02c58d1a3c3902fb1c04744b4011e7f0534e1cd3c07399a2028321e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8164567351341248}",,,,,,,,,,['neutral'],neutral,1 NCT00573495,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.828386/full', 'title': 'Breast Cancer Vaccines: Disappointing or Promising?', 'source': 'Frontiers', 'date': 'Feb 7, 2024', 'snippet': '1Department of Breast Surgery, Fudan University Shanghai Cancer Center, \nShanghai, China; 2Shanghai Medical College, Fudan University, Shanghai, \nChina.', 'thumbnail': 'https://serpapi.com/searches/67246e16f7adbf72b3a17c42/images/118b4528939e1fa7592ae3aa86eb26a696b761f09693649f981bf5b37a25e931.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6253421306610107}",,,,,,,,,,['neutral'],neutral,1 NCT00231153,"{'position': 1, 'link': 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'source': 'Nature', 'date': 'Jun 20, 2024', 'snippet': 'IXA + BEV has activity in heavily pre-treated ovarian cancers and offers \nsignificant improvement in ORR and PFS/OS compared to IXA, despite prior \ntaxane...', 'thumbnail': 'https://serpapi.com/searches/67246e41ef60cb0a53d48499/images/47107da075449fc1019988bf166b4af1ebcfb42fec924bc9b7affa002d67dec5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8542064428329468}","{'position': 2, 'link': 'https://www.nature.com/articles/s41416-022-01717-6', 'title': 'Randomised phase II trial of weekly ixabepilone ± biweekly bevacizumab for platinum-resistant or refractory ovarian/fallopian tube/primary peritoneal cancer', 'source': 'Nature', 'date': 'Feb 11, 2022', 'snippet': 'IXA + BEV is a well-tolerated, effective combination for \nplatinum/taxane-resistant ovarian cancer that extends PFS and likely OS \nrelative to IXA monotherapy.', 'thumbnail': 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Particle Influenza A (H7N9) Vaccine', 'source': 'The New England Journal of Medicine', 'date': 'May 1, 2018', 'snippet': 'Influenza A (H7N9) emerged earlier this year as a health threat in China. \nEfforts to develop a vaccine are under way. This letter presents initial \nphase 1...', 'thumbnail': 'https://serpapi.com/searches/67246e5324296ac82b89b0db/images/100509bb19e552b80e85f2bc2a974879219d0118232c87c77c9cf0556f3cbaf0.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6529706120491028}",,,,,,,,,,['negative'],negative,0 NCT05643794,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/features/pipeline-moves-moderna-pandemic-trial-vaccine-completes/', 'title': 'Pipeline Moves: Moderna’s pandemic influenza vaccine trial completes', 'source': 'Clinical Trials Arena', 'date': '19 Ağu 2024', 'snippet': 'The Clinical Trials Arena team investigates assets in oncology, central \nnervous system and infectious diseases.', 'thumbnail': 'https://serpapi.com/searches/67246e5e48c97d44c3140095/images/bd03762e4d1c3680512db7c2ed210bd87cccb8ac16168dd8120ad87d909cd8af.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8368623852729797}","{'position': 2, 'link': 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recommended the approval of toripalimab-tpzi..."", 'thumbnail': 'https://serpapi.com/searches/67246e6390b57c461dea52f3/images/b823b7b746f85bec3720921eb086662c2cca1686bb1ff1cad4cf28690f29695b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9107452630996704}",,,,,,,,,,['neutral'],neutral,1 NCT04427501,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2029849', 'title': 'SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Oct 28, 2020', 'snippet': 'Virus-neutralizing monoclonal antibodies are predicted to reduce viral \nload, ameliorate symptoms, and prevent hospitalization.', 'thumbnail': 'https://serpapi.com/searches/67246e84b57db83ec2d863ea/images/e9fe7eb8f10f349ef3cd6fd53a6dbaf431e14172c29d97f4db8efb2f6845dafd.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8533226847648621}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2102685', 'title': 'Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'Jul 14, 2021', 'snippet': 'Patients with underlying medical conditions are at increased risk for \nsevere coronavirus disease 2019 (Covid-19).', 'thumbnail': 'https://serpapi.com/searches/67246e84b57db83ec2d863ea/images/e9fe7eb8f10f349eaab4b8da877ebb60e96f7dd055b8bcf63b739e13eaf23f78.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5249709486961365}","{'position': 3, 'link': 'https://www.empr.com/home/news/emergency-use-authorization-eua-bamlanivimab-etesevimab-covid-19/', 'title': 'FDA OKs Emergency Use of Bamlanivimab Plus Etesevimab for COVID-19', 'source': 'Medical Professionals Reference', 'date': 'Feb 10, 2021', 'snippet': ""The Food and Drug Administration (FDA) has issued an Emergency Use \nAuthorization (EUA) for Lilly's severe acute respiratory syndrome..."", 'thumbnail': 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We isolated patient-derived...', 'thumbnail': 'https://serpapi.com/searches/67246eb1a505f7b906091d88/images/80311099b3dea6ef127046f084db1978bbccd77917d98c3b27ac27553bebfdec.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7944258451461792}",,,,,,,,,,['negative'],negative,0 NCT00896532,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1305224', 'title': 'Romosozumab in Postmenopausal Women with Low Bone Mineral Density', 'source': 'The New England Journal of Medicine', 'date': 'Jan 1, 2014', 'snippet': 'Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. The \nmonoclonal antibody romosozumab binds to sclerostin and increases...', 'thumbnail': 'https://serpapi.com/searches/67246ebbb4e8d68e084e05fd/images/ce000a7aa2438030ea0708716f8950e9c83d64b31d8df46423d16202866afaae.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9022723436355591}",,,,,,,,,,['neutral'],neutral,1 NCT02349841,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMc1513236', 'title': 'β-Lactams against Tuberculosis — New Trick for an Old Dog? | NEJM', 'source': 'The New England Journal of Medicine', 'date': 'Jul 13, 2016', 'snippet': 'Meropenem combined with amoxicillin–clavulanic acid not only resisted \nhydrolysis well but also showed synergistic antituberculosis activity.', 'thumbnail': 'https://serpapi.com/searches/67246ec7ec54104fb652d131/images/f484524852228309906f760f26e2f9f72d25ff70a4dcebd09e2bed96172afca1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8760133981704712}",,,,,,,,,,['neutral'],neutral,1 NCT03497975,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/trevi-therapeutics-reports-positive-results-from-the-ph2b3-prism-trial-of-haduvio-in-the-treatment-of-prurigo-nodularis-301577632.html', 'title': 'Trevi Therapeutics Reports Positive Results from the Ph2b/3 PRISM Trial of Haduvio™ in the Treatment of Prurigo Nodularis', 'source': 'PR Newswire', 'date': 'Jun 29, 2022', 'snippet': 'PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage \nbiopharmaceutical company developing an investigational therapy...', 'thumbnail': 'https://serpapi.com/searches/67246ec854605c645e4eef2c/images/b8876216a87cbf0cb969f3fd60fe3aa76468e4c64c0933f077f9c045f3b4a1d9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.666989803314209}",,,,,,,,,,['neutral'],neutral,1 NCT02307682,"{'position': 1, 'link': 'https://www.nature.com/articles/s41433-022-02077-4', 'title': 'Therapeutic response in the HAWK and HARRIER trials using deep learning in retinal fluid volume and compartment analysis | Eye', 'source': 'Nature', 'date': 'May 6, 2022', 'snippet': 'To assess the therapeutic response to brolucizumab and aflibercept by deep \nlearning/OCT-based analysis of macular fluid volumes in neovascular \nage-related...', 'thumbnail': 'https://serpapi.com/searches/67246ee068831e63a4ce282c/images/8281f9befe6b87c5c3fcbc2a166b985357de4fb0729ce937c6d52616d6cdd07d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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2022', 'snippet': 'A clinical trial of 22 adults with Fragile X syndrome showed combining \nlovastatin and minocycline significantly improved several behaviors.', 'thumbnail': 'https://serpapi.com/searches/67246ef14a4a1d3f6d80ff44/images/7e849d0ecc377bde925146a9998ca9bcbc7f78921f598e2114ac2d0d10fed76a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6776238083839417}",,,,,,,,,,['neutral'],neutral,1 NCT03575104,"{'position': 1, 'link': 'https://www.empr.com/home/news/quviviq-approved-for-the-treatment-of-insomnia/', 'title': 'Quviviq Approved for the Treatment of Insomnia', 'source': 'Medical Professionals Reference', 'date': 'Jan 10, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Quviviq™ (daridorexant) \nfor the treatment of adults with insomnia characterized by...', 'thumbnail': 'https://serpapi.com/searches/67246efda5aae9a0ed5c355a/images/764c67043fc8e201093a2346628f55a6653f480e317835d67373e8bb59ab6882.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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2023', 'snippet': 'The cancer stem cell (CSC, also named tumor-initiating cell) model states \nthat tumor growth is driven by a subset of CSCs.', 'thumbnail': 'https://serpapi.com/searches/67246f5b1397ba76f05c85d3/images/abb7f9cdeafdae3611ceb5a3ed650589da8448fba8918914f3db7a867dfd4802.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9208656549453735}",,,,,,,,,,['neutral'],neutral,1 NCT01730534,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1812389', 'title': 'Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes', 'source': 'The New England Journal of Medicine', 'date': 'Nov 10, 2018', 'snippet': 'The cardiovascular safety profile of dapagliflozin, a selective inhibitor \nof sodium–glucose cotransporter 2 that promotes glucosuria in...', 'thumbnail': 'https://serpapi.com/searches/67246f0ca505f7b93bf42878/images/90964dc8e908f0ac87c63016d4e9cb1c36f8c941e0d6bafae56cc8c81682727c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'date': 'May 31, 2024', 'snippet': 'In this phase 3, double-blind, three-way crossover trial, we randomly \nassigned participants at least 12 years of age with type 1 or type 2...', 'thumbnail': 'https://serpapi.com/searches/67246f1164f11d5673dd9e35/images/0d00320807e3166cbf2fd9cb2da68a41e91c92282ff51e40f301d7b240411188.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9219282865524292}","{'position': 2, 'link': 'https://angioedemanews.com/news/young-children-with-hae-tested-new-clinical-trial-oral-sebetralstat/', 'title': 'Young children with HAE to be tested in new clinical trial of oral sebetralstat', 'source': 'Angioedema News', 'date': 'Jul 8, 2024', 'snippet': 'KalVista Pharmaceuticals has started a clinical trial to test the oral \nmedication sebetralstat as an on-demand treatment for swelling attacks in \nchildren with...', 'thumbnail': 'https://serpapi.com/searches/67246f1164f11d5673dd9e35/images/0d00320807e3166c7fec182e12575e8df11001ca2a43073894132d0e71205db7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9251697063446045}","{'position': 3, 'link': 'https://angioedemanews.com/news/phase-3-trial-sebetralstat-kvd900-fully-enrolled/', 'title': 'Phase 3 trial of sebetralstat (KVD900) in treating attacks fully...', 'source': 'Angioedema News', 'date': 'Jul 10, 2023', 'snippet': 'The Phase 3 clinical trial of oral sebetralstat as an on-demand treatment \nfor swelling attacks in people with hereditary angioedema (HAE) has reached \nits...', 'thumbnail': 'https://serpapi.com/searches/67246f1164f11d5673dd9e35/images/0d00320807e3166cfc62b4722696e646749b48dc16437e02221af7ffdd40368b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8326175808906555}","{'position': 4, 'link': 'https://angioedemanews.com/news/targeted-treated-attack-number-met-phase-3-sebetralstat-trial/', 'title': 'Targeted treated attack number met in Phase 3 sebetralstat trial', 'source': 'Angioedema News', 'date': 'Dec 4, 2023', 'snippet': 'The Phase 3 KONFIDENT trial, testing oral 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'snippet': 'SER-109 is an investigational microbiome therapeutic composed of purified \nFirmicutes spores for the treatment of recurrent C. difficile infection.', 'thumbnail': 'https://serpapi.com/searches/67247030a2e99c0092bb1df0/images/9a18245629394d14261812bce5f20194ee1d80b27fd685c2266107ed00be258f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8969530463218689}","{'position': 2, 'link': 'https://www.empr.com/home/news/vowst-approved-to-prevent-recurrent-c-difficile-infection/', 'title': 'Vowst Approved to Prevent Recurrent C. difficile Infection - MPR', 'source': 'Medical Professionals Reference', 'date': 'Apr 27, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Vowst™ (fecal \nmicrobiota spores, live-brpk) to prevent the recurrence of Clostridioides...', 'thumbnail': 'https://serpapi.com/searches/67247030a2e99c0092bb1df0/images/9a18245629394d14cf12b9a9359f5af6ddbbb064a53c33e637130e0bab84139e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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2024', 'snippet': 'A high dose of oral PSC treatment bexotegrast safely reduced markers of \nprimary sclerosing cholangitis progression in a trial.', 'thumbnail': 'https://serpapi.com/searches/67247340e92456efd939a92c/images/a981bf690932686f62f003d6fb4e02ae86310a3ed29e944dd6f6ccd830e01be9.png', 'sentiment': 'positive', 'sentiment_prob': 0.5395350456237793}","{'position': 2, 'link': 'https://liverdiseasenews.com/news/bexotegrast-shows-positive-signs-psc-treatment-phase-2-trial/', 'title': 'Bexotegrast shows positive signs as PSC treatment in Phase 2 trial', 'source': 'Liver Disease News', 'date': 'Feb 21, 2024', 'snippet': 'All doses of bexotegrast tested in primary sclerosing cholangitis patients \nin a clinical trial showed signs of efficacy as a PSC treatment.', 'thumbnail': 'https://serpapi.com/searches/67247340e92456efd939a92c/images/a981bf690932686fcc0e67eb7231d9266acc97002d366caeb284961dafb54bbd.png', 'sentiment': 'positive', 'sentiment_prob': 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for eligible adults with multiple..."", 'thumbnail': 'https://serpapi.com/searches/67247208ce1a756514f99615/images/5b2eb8d3504ae4117fe7a014e1e9febb662fd0731d8f402c71ecb91cf9d86970.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7035571336746216}",,,,,,,"['positive', 'neutral', 'neutral', 'neutral']",neutral,1 NCT02921789,"{'position': 1, 'link': 'https://www.nature.com/articles/s41581-021-00427-1', 'title': 'Therapeutic trials in adult FSGS: lessons learned and the road forward', 'source': 'Nature', 'date': 'May 20, 2021', 'snippet': 'Focal segmental glomerulosclerosis (FSGS) is not a specific disease entity \nbut a lesion that primarily targets the podocyte.', 'thumbnail': 'https://serpapi.com/searches/672472e4123457faf321159e/images/91c8c349f7d041541f1298b8e1a8e19d546e36946c46f346ea925bbb33c363a5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8861932754516602}",,,,,,,,,,['neutral'],neutral,1 NCT02949128,"{'position': 1, 'link': 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'date': 'Sep 17, 2007', 'snippet': 'Topiramate added to CBT improved the efficacy of the later, increasing \nbinge remission and weight loss in the short run. 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Previous meta-analyses have...', 'thumbnail': 'https://serpapi.com/searches/672490af213c87213e78a155/images/a8a596586ccdf9288b258fc013d60a84453bc12312d519e3b51f27300b6cd05d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6487038731575012}",,,,,,,,,,['neutral'],neutral,1 NCT02770716,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2008290', 'title': 'Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome', 'source': 'The New England Journal of Medicine', 'date': 'Mar 3, 2021', 'snippet': 'The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome \n(HRS-1) in many parts of the world and is part of the clinical...', 'thumbnail': 'https://serpapi.com/searches/672490b2e1c276ffa027f432/images/232e6feb41b9078853710ecb24e6b7906a18ad72ae48b1802d20980671c82e04.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9108983874320984}","{'position': 2, 'link': 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'title': 'Measuring Blood Vessel Activity May Predict Multiple Myeloma Prognosis', 'source': 'Myeloma Research News', 'date': 'Feb 4, 2019', 'snippet': 'A panel of blood markers that identifies tumors with more active blood \nvessels may help stratify multiple myeloma patients according to...', 'thumbnail': 'https://serpapi.com/searches/6724935674f0a4d3e31994fb/images/f529f217648b4dd060f55e4d1bb172107749bf649a1328cea471f72484866924.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9216383099555969}",,,,,,,,,,['neutral'],neutral,1 NCT02763579,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1809064', 'title': 'First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Sep 25, 2018', 'snippet': 'Enhancing tumor-specific T-cell immunity by inhibiting programmed death \nligand 1 (PD-L1)–programmed death 1 (PD-1) signaling has shown...', 'thumbnail': 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high/intermediate-risk myelofibrosis \n(MF) received momelotinib (MMB; JAK1/2 inhibitor) between 2009...', 'thumbnail': 'https://serpapi.com/searches/672492b754163d250a675ac0/images/9bbde2d4e4063c4f5b111a1dd49920122d91898c59b23198faa99109e4af9f76.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9240283966064453}",,,,,,,,,,['neutral'],neutral,1 NCT05413668,"{'position': 1, 'link': 'https://www.itnonline.com/content/new-gadolinium-free-mri-contrast-agent-advances-safer-patient-care', 'title': 'New Gadolinium-Free MRI Contrast Agent Advances Safer Patient Care', 'source': 'Imaging Technology News', 'date': 'Mar 9, 2023', 'snippet': 'Reveal Pharmaceuticals doses first subjects in Phase 1 Clinical Trial of \nRVP‑001.', 'thumbnail': 'https://serpapi.com/searches/672492c46f9f6308c9430536/images/be7b6cb654a88ece1fd6555c06013d95534a7bff6edd2005d26d7f4fc23a359d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8355599045753479}",,,,,,,,,,['neutral'],neutral,1 NCT03835975,"{'position': 1, 'link': 'https://www.empr.com/home/news/fda-approves-20-valent-pneumococcal-conjugate-vaccine-prevnar-20/', 'title': 'FDA Approves 20-Valent Pneumococcal Conjugate Vaccine Prevnar 20', 'source': 'Medical Professionals Reference', 'date': 'Jun 9, 2021', 'snippet': 'The Food and Drug Administration (FDA) has granted accelerated approval to \nPrevnar 20™ (pneumococcal 20-valent conjugate vaccine) for the...', 'thumbnail': 'https://serpapi.com/searches/672491651fc7c5650202e6c3/images/60dd0eec4bdf54faefb324d156c2a92473782451e0ee83e4a6723f1e8440d6e9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7787243127822876}","{'position': 2, 'link': 'https://www.koreabiomed.com/news/articleView.html?idxno=13140', 'title': 'Pfizer scores European approval for 20-valent pneumococcal vaccine', 'source': 'KBR', 'date': 'Feb 16, 2022', 'snippet': 'Pfizer, which dominated the global pneumococcal vaccine market with \n13-valent Prevnar 13, said it won approval for a 20-valent vaccine in \nEurope.', 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'https://onlinelibrary.wiley.com/doi/10.1002/ehf2.14097', 'title': 'Sacubitril/valsartan in heart failure: efficacy and safety in and outside clinical trials', 'source': 'Wiley Online Library', 'date': 'Aug 3, 2022', 'snippet': 'The angiotensin receptor-neprilysin inhibitor sacubitril/valsartan (S/V) \nhas an important role in the treatment of patients with HFrEF.', 'thumbnail': 'https://serpapi.com/searches/672492299062f89c9a2d4421/images/b02018af1609ca04b2dfdf536d69563426a6d7d9294026ebd3230e53ba6e43bd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7455959320068359}","{'position': 2, 'link': 'https://www.news-medical.net/news/20231218/Common-heart-medication-causes-false-positives-on-Alzheimers-blood-test.aspx', 'title': ""Common heart medication causes false positives on Alzheimer's blood test"", 'source': 'News-Medical', 'date': 'Dec 18, 2023', 'snippet': 'The drug Entresto (sacubitril/valsartan) which is commonly used for the \ntreatment of cardiac failure leads to a marked 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2023', 'snippet': 'This review discusses a narrative opinion and critical review of COPD. We \npresent different aspects of the disease, from cellular and inflammatory \nresponses to...', 'thumbnail': 'https://serpapi.com/searches/672495cff9f904fd8c1736a4/images/22ef429ddf0ab26523683aaea1707f4fcb9e1d6fbc41db6f88a69da681e6c5e6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.930492639541626}",,,,,,,,,,['neutral'],neutral,1 NCT00297388,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/double-blind-study-doses-long-acting-risperidone/', 'title': 'A 1-Year Double-Blind Study of 2 Doses of Long-Acting Risperidone in Stable Patients With Schizophrenia or Schizoaffective Disorder.', 'source': 'Psychiatrist.com', 'date': 'Oct 29, 2023', 'snippet': 'George M. Simpson, MD; Ramy A. Mahmoud, MD; Robert A. Lasser, MD; Mary \nKujawa, MD; Cynthia A. Bossie, PhD; Ibrahim Turkoz, MS; Steven Rodriguez, \nMS;...', 'thumbnail': 'https://serpapi.com/searches/672494f0dda9d931278ca58a/images/02fe05bc2c830983319438bc90028823b4d12d310ff644ef93510bbefacbc5cf.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9112716317176819}",,,,,,,,,,['neutral'],neutral,1 NCT03339882,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/abs/pii/S0378874118319159', 'title': 'Effect of cimicifuga racemosa on menopausal syndrome caused by LHRH-a in breast cancer', 'source': 'ScienceDirect.com', 'date': 'Jun 28, 2019', 'snippet': 'Cimicifuga racemose is previously proved effective on nature menopausal \nsyndrome (MPS). However, its clinical value in treating with MPS...', 'thumbnail': 'https://serpapi.com/searches/67249513e10f0a1c4155b849/images/8d71ce17d4a38efa3eeee8007d304b242e0e179d7d75ce2aaa79b0e23cdb6fae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8092305064201355}",,,,,,,,,,['neutral'],neutral,1 NCT01830920,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.864509/full', 'title': 'A Process for the Design and Development of Novel Bone Morphogenetic Protein-7 (BMP-7) Mimetics With an Example: THR-184', 'source': 'Frontiers', 'date': 'Feb 12, 2024', 'snippet': '1Division of Cardiology, Mass General Hospital/Harvard, Boston, MA, United \nStates; 2Harvard Medical School, Boston, MA, United States; 3Therapeutics \nBy...', 'thumbnail': 'https://serpapi.com/searches/67249522c05eb58836389c51/images/6189dfe4b7d087c087c3542e0b29cf18df8904c810e8f02a28a51869f9bb14b9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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dose-escalation study of the \nnovel checkpoint kinase 1 (Chk1) inhibitor SRA737.', 'thumbnail': 'https://serpapi.com/searches/672495677a12fda5c3c3fd70/images/3802f4fc94fe3d3ca4a6f54fdb21ea2157bd2c8a52765a82426440e6b85eb976.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9178969860076904}",,,,,,,,,,['neutral'],neutral,1 NCT03901144,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/ced.15141', 'title': 'Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis', 'source': 'Wiley Online Library', 'date': 'Feb 15, 2022', 'snippet': 'This study compares the barrier-strengthening properties of a new \nmoisturizer, containing urea and glycerol, to a glycerol-containing...', 'thumbnail': 'https://serpapi.com/searches/672494330197dd91dd3b7bc8/images/db36806806bb8ffd3a2bd787c969b30d886ec4841ac045637141a89bbd1b359d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'snippet': ""Trikafta's developer Vertex Pharmaceuticals presented the findings from two \nopen-label extension studies at the 2023 NACFC in Phoenix."", 'thumbnail': 'https://serpapi.com/searches/672494af58e4331656c95ff4/images/e32d69fb4ffb6a3ce49042095a4c0bd2f7e6d13b20efbc3a69ea1c68bc32b086.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5179463624954224}","{'position': 2, 'link': 'https://www.empr.com/home/news/trikafta-approved-for-children-with-cystic-fibrosis-as-young-as-2-years/', 'title': 'Trikafta Approved for Children With Cystic Fibrosis as Young as 2 Years', 'source': 'Medical Professionals Reference', 'date': 'Apr 26, 2023', 'snippet': 'The Food and Drug Administration (FDA) has expanded the approval of \nTrikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor) to include \nchildren with cystic...', 'thumbnail': 'https://serpapi.com/searches/672494af58e4331656c95ff4/images/e32d69fb4ffb6a3c532a877f405c094fbca3224dd71053e38fc5b2ad2acc6ca8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8349416851997375}","{'position': 3, 'link': 'https://cysticfibrosisnewstoday.com/news/fda-expands-approval-trikafta-younger-children-ages-2-to-5/', 'title': 'FDA expands its approval of Trikafta to children ages 2 to 5', 'source': 'Cystic Fibrosis News Today', 'date': 'Apr 27, 2023', 'snippet': 'The US Food and Drug Administration (FDA) has approved the expanded use of \nTrikafta (elexacaftor, tezacaftor, and ivacaftor) to children with cystic \nfibrosis (...', 'thumbnail': 'https://serpapi.com/searches/672494af58e4331656c95ff4/images/e32d69fb4ffb6a3ce54ba307495ab85b8f1b02995383535ae24edfbdb7af1c6d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5731809139251709}","{'position': 4, 'link': 'https://cysticfibrosisnewstoday.com/news/vertex-phase-3-trials-vx121-vx561-tezacaftor-triple-combination-cf-therapy/', 'title': 'Vertex Planning Phase 3 Trials in New Triple Combo Therapy for CF', 'source': 'Cystic Fibrosis News Today', 'date': 'Jul 30, 2021', 'snippet': 'Vertex Pharmaceuticals is initiating two Phase 3 clinical trials into the \nsafety and efficacy of a potentially new, next-generation triple \ncombination therapy...', 'thumbnail': 'https://serpapi.com/searches/672494af58e4331656c95ff4/images/e32d69fb4ffb6a3c5918e0c85a5fcb40ea68330f07486365d3c56c4c19209823.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.881530225276947}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT04559568,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1002/mco2.481', 'title': 'Drug development advances in human genetics‐based targets - Zhang - 2024 - MedComm', 'source': 'Wiley Online Library', 'date': 'Feb 9, 2024', 'snippet': 'Progress in drug discovery based on targets with favorable LOF variants \nidentified by WES, WGS, and GWAS. 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Janjigian Joins Sairiyo Therapeutics Scientific and Clinical Advisory Board', 'source': 'Psychedelic Alpha', 'date': 'May 20, 2022', 'snippet': 'Toronto, Ontario–(Newsfile Corp. – March 4, 2021) – PharmaDrug Inc. (CSE: \nBUZZ) (OTC Pink: LMLLF) (“PharmaDrug” or the “Company”) wholly-owned \nsubsidiary…', 'thumbnail': 'https://serpapi.com/searches/672495eb9e38e5ac2d35e3fa/images/cb5cdcd3d99d79ae36172e4db438d60dea625b7feca2b5ee41b00e0ff37b6c54.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8563597202301025}","{'position': 3, 'link': 'https://immuno-oncologynews.com/2020/10/28/opdivo-combo-extends-survival-advanced-stomach-and-esophageal-cancers-phase-3-trial-shows/', 'title': 'Opdivo Combo Found to Extend Survival in Advanced Stomach, Esophageal Cancers', 'source': 'Immuno-Oncology News', 'date': 'Oct 28, 2020', 'snippet': 'Adding Opdivo (nivolumab) to standard first-line chemotherapy significantly \nextends overall survival and delays disease progression or death in adults.', 'thumbnail': 'https://serpapi.com/searches/672495eb9e38e5ac2d35e3fa/images/cb5cdcd3d99d79aeb71ccacbecc3004c250e0f8b31ebcc91c3e552eb7d74d05e.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7953006625175476}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03765073,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2116045', 'title': 'Potential for Maternally Administered Vaccine for Infant Group B Streptococcus', 'source': 'The New England Journal of Medicine', 'date': 'Jul 19, 2023', 'snippet': 'Natural history studies have correlated serotype-specific anti–capsular \npolysaccharide (CPS) IgG in newborns with a reduced risk of group B...', 'thumbnail': 'https://serpapi.com/searches/672498f0707fd3a645c4accf/images/ae473016b78922717e66073e7fbaad9386e2c51dc139e4c0c1e2ec9dcc41bd8a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8743211627006531}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/maternal-vaccine-candidate-for-gbs-prevention-in-infants-gets-breakthrough-tx-status/', 'title': 'Maternal Vaccine Candidate for GBS Prevention in Infants Gets Breakthrough Tx Status', 'source': 'Medical Professionals Reference', 'date': 'Sep 7, 2022', 'snippet': 'The Food and Drug Administration (FDA) has granted Breakthrough Therapy \ndesignation to an investigational Group B Streptococcus (GBS) vaccine \ncandidate.', 'thumbnail': 'https://serpapi.com/searches/672498f0707fd3a645c4accf/images/ae473016b7892271d93cd3cf76382b11736bcaa3388aedcfb227faa3102069a6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6908876299858093}","{'position': 3, 'link': 'https://www.researchgate.net/figure/GBS-vaccine-candidates-in-the-development-pathway_tbl1_368357442', 'title': 'GBS vaccine candidates in the development pathway', 'source': 'ResearchGate', 'date': 'Jul 5, 2023', 'snippet': 'Purpose of review: Intrapartum antibiotic prophylaxis (IAP) is currently \nthe only preventive approach against clinical consequences of maternal \nGroup B...', 'thumbnail': 'https://serpapi.com/searches/672498f0707fd3a645c4accf/images/ae473016b78922718fe6ef4b2d6d0123810927249b8cf3da1797cd27b40eac75.png', 'sentiment': 'neutral', 'sentiment_prob': 0.901256799697876}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT03202758,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-023-02497-z', 'title': 'First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial', 'source': 'Nature', 'date': 'Aug 10, 2023', 'snippet': 'The single-arm, phase 1b/2 MEDITREME trial evaluated the safety and \nefficacy of durvalumab plus tremelimumab combined with mFOLFOX6 \nchemotherapy in first line.', 'thumbnail': 'https://serpapi.com/searches/67249942069e5753851d323e/images/147997f720ff5d3c0b01aa31158c41fdd03881f65e9f39b61c62a48875ab60d0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8836589455604553}",,,,,,,,,,['neutral'],neutral,1 NCT00270374,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1100171', 'title': 'Effect of Nesiritide in Patients with Acute Decompensated Heart Failure', 'source': 'The New England Journal of Medicine', 'date': 'Jul 7, 2011', 'snippet': 'Nesiritide is approved in the United States for early relief of dyspnea in \npatients with acute heart failure. Previous meta-analyses have...', 'thumbnail': 'https://serpapi.com/searches/672496317ebde5567687ae56/images/e94bbe97f3a8870b7bccabadb7481bc6e5615f5cf5373931bb9f6ba1db24f5e5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6487038731575012}",,,,,,,,,,['neutral'],neutral,1 NCT05053165,"{'position': 1, 'link': 'https://liverdiseasenews.com/news/lb-p8-probiotic-primary-sclerosing-cholangitis-fda-fast-track/', 'title': 'LB-P8 probiotic on FDA fast track for primary sclerosing cholangitis', 'source': 'Liver Disease News', 'date': 'Apr 3, 2024', 'snippet': 'The FDA has given fast track status to LB-P8, an experimental probiotic \nheading to Phase 2 clinical testing for primary sclerosing...', 'thumbnail': 'https://serpapi.com/searches/67249642cf32e043b585f875/images/33425ed71f2e5c3662df615e19f9fe48b5cdb5acde244f5451250d522a64a3ec.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7736496925354004}","{'position': 2, 'link': 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improved the clinical benefit and \nsurvival of patients with metastatic triple-negative breast cancer \nwithout...', 'thumbnail': 'https://serpapi.com/searches/672496c9861b9da4bf288707/images/f6356496a2138f0ea35606c1d72617db8b1c36321329edc12c4f0808ab394cf6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5897843837738037}",,,,,,,,,,['neutral'],neutral,1 NCT00833781,"{'position': 1, 'link': 'https://www.sciencedirect.com/science/article/pii/S2405844024030020', 'title': 'The clinical impact of mRNA therapeutics in the treatment of cancers, infections, genetic disorders, and autoimmune diseases', 'source': 'ScienceDirect.com', 'date': 'Mar 15, 2024', 'snippet': 'mRNA-based therapeutics have revolutionized medicine and the pharmaceutical \nindustry. The recent progress in the optimization and...', 'thumbnail': 'https://serpapi.com/searches/672496d0dda9d931278ca5e1/images/22e3ee5f21a60caf91746a2e4308712cc287a7059885b8e47423abf95c199940.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6543469429016113}",,,,,,,,,,['positive'],positive,1 NCT03443869,"{'position': 1, 'link': 'https://www.empr.com/home/news/prevymis-approved-for-cmv-disease-prevention-in-kidney-transplant-recipients/', 'title': 'Prevymis Approved for CMV Disease Prevention in Kidney Transplant Recipients', 'source': 'Medical Professionals Reference', 'date': 'Jun 6, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Prevymis (letermovir) \nfor prophylaxis of cytomegalovirus (CMV) disease in adult kidney \ntransplant...', 'thumbnail': 'https://serpapi.com/searches/672496dbb2ebae2669c54936/images/56516c55294ca446d206f59836c8fb01591b859f2a3b0ef1f61f7e737bcdde57.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8343550562858582}","{'position': 2, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/fda-to-review-letermovir-for-cmv-disease-prevention-in-kidney-transplant-recipients/', 'title': 'FDA to Review Letermovir for CMV Disease Prevention in Kidney Transplant Recipients', 'source': 'Medical Professionals Reference', 'date': 'Feb 17, 2023', 'snippet': 'The Food and Drug Administration (FDA) has accepted for Priority Review the \nsupplemental New Drug Application (sNDA) for letermovir for...', 'thumbnail': 'https://serpapi.com/searches/672496dbb2ebae2669c54936/images/56516c55294ca44682e1407e2b65036c222006ee2f817b6ca4163f13bb77f5a2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8933071494102478}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01017185,"{'position': 1, 'link': 'https://www.nature.com/articles/s41417-019-0129-3', 'title': 'Oncolytic activity of HF10 in head and neck squamous cell carcinomas', 'source': 'Nature', 'date': 'Sep 3, 2019', 'snippet': 'HF10 killed HNSCC cells and induced antitumoral 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NCT01621490,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-34877-3', 'title': 'A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma', 'source': 'Nature', 'date': 'Nov 25, 2022', 'snippet': 'Acral melanoma is a dismal subtype of melanoma occurring in glabrous acral \nskin, and has a higher incidence in East Asians.', 'thumbnail': 'https://serpapi.com/searches/6724985c8d147358ee7a5b87/images/5a170dd49d7ff19668ec375dd47cf8f742cc5eb063cc2e793eb7bfd360a11ec6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6061059236526489}",,,,,,,,,,['neutral'],neutral,1 NCT04634409,"{'position': 1, 'link': 'https://investor.lilly.com/news-releases/news-release-details/lillys-bebtelovimab-receives-emergency-use-authorization', 'title': ""Lilly's bebtelovimab receives Emergency Use Authorization for the treatment of mild-to-moderate COVID-19"", 'source': 'Eli Lilly and Company', 'date': 'Feb 11, 2022', 'snippet': 'FDA has authorized bebtelovimab for emergency use for certain \nnon-hospitalized patients with mild-to-moderate COVID-19 at high risk of \nprogression to severe...', 'thumbnail': 'https://serpapi.com/searches/67249882483e5b5046d32623/images/bcfd507f2e1a5fa8cbe4eb62dd8327c46f8f5e1088c18aa1d143a5a7b24fc6c0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8874615430831909}",,,,,,,,,,['neutral'],neutral,1 NCT02688608,"{'position': 1, 'link': 'https://www.targetedonc.com/view/immune-checkpoint-inhibitors-show-promising-efficacy-in-anaplastic-thyroid-cancer', 'title': 'Immune Checkpoint Inhibitors Show Promising Efficacy in Anaplastic Thyroid Cancer', 'source': 'Targeted Oncology', 'date': 'Sep 1, 2022', 'snippet': 'Immune checkpoint blockade was well tolerated and had a similar toxicity \nprofile to PD-1/PD-L1-targeting therapies for patients with anaplastic \nthyroid cancer...', 'thumbnail': 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mRNA-1273 SARS-CoV-2 Vaccine in Adolescents', 'source': 'The New England Journal of Medicine', 'date': 'Aug 11, 2021', 'snippet': 'The incidence of coronavirus disease 2019 (Covid-19) among adolescents \nbetween 12 and 17 years of age was approximately 900 per 100000...', 'thumbnail': 'https://serpapi.com/searches/6724984e39e232bf613925e9/images/a22b2ba20b90523461c45bf31554beb589c7ea27984fecc83bbd664ee3c47ed0.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6496191024780273}",,,,,,,,,,['neutral'],neutral,1 NCT00721409,"{'position': 1, 'link': 'https://breastcancer-news.com/2018/11/05/faslodex-ibrance-combo-improves-survival-advanced-breast-cancer-patients/', 'title': 'In Breast Cancer, Ibrance-Faslodex Combo Improves Survival, Phase 3 Data Shows', 'source': 'breastcancer-news.com', 'date': 'Nov 5, 2018', 'snippet': ""Adding Pfizer's Ibrance to standard treatment Faslodex significantly \nextended the survival of advanced breast cancer patients in a Phase 3..."", 'thumbnail': 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Natural \nKiller (NK) cells are unique immune cells capable of efficient...', 'thumbnail': 'https://serpapi.com/searches/6724997cf410445e4dd81bea/images/8486bb24d90ce54f131b1300677e69e01e092bdb25d2571c21e30011a498f49c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7305735945701599}",,,,,,,,,,['neutral'],neutral,1 NCT02346201,"{'position': 1, 'link': 'https://www.nia.nih.gov/news/ritalin-reduced-apathy-nia-funded-alzheimers-clinical-trial', 'title': 'Ritalin reduced apathy in NIA-funded Alzheimer’s clinical trial', 'source': 'National Institute on Aging (.gov)', 'date': 'Dec 2, 2021', 'snippet': ""The stimulant drug methylphenidate, commonly known as Ritalin, safely \nreduced measures of apathy among adults with Alzheimer's disease,..."", 'thumbnail': 'https://serpapi.com/searches/6724999c23793852a787739e/images/6b698ca54eb99d9f08038d4f9f017745aae9508cb32db38826d41cce8bcbb456.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7688660621643066}",,,,,,,,,,['neutral'],neutral,1 NCT05400655,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2203067', 'title': 'Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria', 'source': 'The New England Journal of Medicine', 'date': 'Aug 3, 2022', 'snippet': 'In this small trial, L9LS administered intravenously or subcutaneously \nprotected recipients against malaria after controlled infection, without \nevident safety...', 'thumbnail': 'https://serpapi.com/searches/67249e50c76a3a3c4c1e19a5/images/6adfa40f2d3baed1b9767372897c43f0cf0bcbdcb3ee0dcd19cccc6fb0de98de.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7041404843330383}",,,,,,,,,,['neutral'],neutral,1 NCT03401112,"{'position': 1, 'link': 'https://sicklecellanemianews.com/news/imara-begins-phase-2-sickle-cell-trial-testing-imr-687/', 'title': 'Imara Begins Phase 2 Sickle Cell Disease Trial Testing IMR-687 in Adults', 'source': 'Sickle Cell Disease News', 'date': 'Feb 15, 2018', 'snippet': 'Imara, a pharmaceutical company developing new therapies for sickle cell \ndisease, has successfully dosed the first patient enrolled in its...', 'thumbnail': 'https://serpapi.com/searches/67249e62d19f158f2a67b89b/images/f1ef6abadf9a8257e6b3ba7ce2b8e368c9178cf30aae0171ea793fd2d8c210bb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.692392110824585}",,,,,,,,,,['neutral'],neutral,1 NCT03243851,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01637-8', 'title': 'From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress', 'source': 'Nature', 'date': 'Oct 20, 2023', 'snippet': 'Glioblastoma, a rare, and highly lethal form of brain cancer, poses \nsignificant challenges in terms of therapeutic resistance, and poor...', 'thumbnail': 'https://serpapi.com/searches/672499ce21b01b4574751d5d/images/9255cf984277a42a16d30ac90112053eb03ca392fbcd48ae7d9d778c3e5bdefc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5414822101593018}",,,,,,,,,,['neutral'],neutral,1 NCT03358875,"{'position': 1, 'link': 'https://www.biopharminternational.com/view/european-commission-approves-tislelizumab-for-non-small-cell-lung-cancer', 'title': 'European Commission Approves Tislelizumab for Non-Small Cell Lung Cancer', 'source': 'BioPharm International', 'date': 'Apr 25, 2024', 'snippet': 'The approval, given across three indications, follows a previous approval \nfor second-line use in esophageal squamous cell carcinoma.', 'thumbnail': 'https://serpapi.com/searches/672499d0f60b6fda68648472/images/4402b2d71cb8c0a922febd88cd962a0a74e2b8c714c10ff535bab0fdb255cbe7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8108032941818237}","{'position': 2, 'link': 'https://immuno-oncologynews.com/2020/12/09/tislelizumab-safely-prolongs-survival-advanced-lung-cancer-patients-interim-data-show/', 'title': 'Tislelizumab Safely Prolongs Survival in Advanced Lung Cancer Patients, Interim Data Show', 'source': 'Immuno-Oncology News', 'date': 'Dec 9, 2020', 'snippet': 'Interim data from a Phase 3 trial showed tislelizumab safely prolonged the \nsurvival of adults with advanced non-small cell lung cancer.', 'thumbnail': 'https://serpapi.com/searches/672499d0f60b6fda68648472/images/4402b2d71cb8c0a969a197c0dd4e6d493c44d9543d41cd23745dfa57d21b37ed.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5863035321235657}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04014335,"{'position': 1, 'link': 'https://www.prnewswire.com/news-releases/ionis-presents-positive-phase-2-data-in-patients-with-iga-nephropathy-at-american-society-of-nephrologys-kidney-week-2022-301669838.html', 'title': ""Ionis presents positive Phase 2 data in patients with IgA Nephropathy at American Society of Nephrology's Kidney Week 2022"", 'source': 'PR Newswire', 'date': 'Nov 7, 2022', 'snippet': 'PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today presented \npositive results from a Phase 2 clinical study of IONIS-FB-LRx in...', 'thumbnail': 'https://serpapi.com/searches/672499d1b4b72d4dda145d04/images/1da0126ac4ad69135f9885336636cf35a3e1380e46cd4893b32932f0d5e61b41.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5928696990013123}",,,,,,,,,,['neutral'],neutral,1 NCT02305758,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-018-0343-z', 'title': 'A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer', 'source': 'Nature', 'date': 'Dec 11, 2018', 'snippet': 'Metastatic colorectal cancer (mCRC) has low survival rates. We assessed if \naddition of veliparib, concurrent to FOLFIRI, improves survival...', 'thumbnail': 'https://serpapi.com/searches/672499f5fda26d6e63e8d6a7/images/30fc77bc1072572a1529439b9e3588d04f2700ed25edce8ed8a943900fdba428.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7744810581207275}",,,,,,,,,,['neutral'],neutral,1 NCT02343120,"{'position': 1, 'link': 'https://www.onclive.com/view/indirect-comparison-of-efficacy-of-zanubrutinib-versus-acalabrutinib-in-the-treatment-of-patients-with-relapsed-or-refractory-mantle-cell-lymphoma', 'title': 'Indirect Comparison of Efficacy of Zanubrutinib Versus Acalabrutinib in the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma', 'source': 'OncLive', 'date': 'Jul 5, 2024', 'snippet': 'The study assessed the comparative efficacy of zanubrutinib vs \nacalabrutinib in patients with R/R MCL, in the absence of head-to-head \nclinical trials.', 'thumbnail': 'https://serpapi.com/searches/67249a1b163bdfc2b2af4f9e/images/5d7cf62f5bc82b967eb4a5f5b3e50b0e0fa113407117009cae964805ea289d0d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.884205162525177}",,,,,,,,,,['neutral'],neutral,1 NCT01644890,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0391-z', 'title': 'A multi-national, randomised, open-label, parallel, phase III non-inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients', 'source': 'Nature', 'date': 'Feb 12, 2019', 'snippet': 'NK105 is a novel nanoparticle drug delivery formulation that encapsulates \npaclitaxel (PTX) in polymeric micelles. We conducted an open-label...', 'thumbnail': 'https://serpapi.com/searches/67249a25e281eed93b036019/images/3733c9f82ee4de973dd95ab1bd152e7a80d8dab9d601247990d4e636a4bb13b9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8983117938041687}",,,,,,,,,,['neutral'],neutral,1 NCT05553366,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209870', 'title': 'Selective Inhibition of NaV1.8 with VX-548 for Acute Pain', 'source': 'The New England Journal of Medicine', 'date': 'Aug 2, 2023', 'snippet': 'The NaV1.8 voltage-gated sodium channel, expressed in peripheral \nnociceptive neurons, plays a role in transmitting nociceptive signals.', 'thumbnail': 'https://serpapi.com/searches/67249e1517b10ef88bd2d2a2/images/acbb14466dfc0ad8c2a49d072f5341d771c1068f496f15e6ba02141eb4d041e4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8272075057029724}",,,,,,,,,,['neutral'],neutral,1 NCT04123886,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2021.628332/full', 'title': 'The TRAIL in the Treatment of Human Cancer: An Update on Clinical Trials', 'source': 'Frontiers', 'date': 'Mar 10, 2021', 'snippet': 'TRAIL (tumor-necrosis factor related apoptosis-inducing ligand, CD253) and \nits death receptors TRAIL-R1 and TRAIL-R2 selectively trigger the...', 'thumbnail': 'https://serpapi.com/searches/67249e1b6273fb68b4d8233e/images/cb6099d4c8c44412db4b14e58308af37a2b1d5b7914815bbee3f4001605660d6.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7822306156158447}",,,,,,,,,,['neutral'],neutral,1 NCT01335477,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1402584', 'title': 'Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis', 'source': 'The New England Journal of Medicine', 'date': 'May 18, 2014', 'snippet': 'A phase 2 trial suggested that treatment with 150 mg of nintedanib twice \ndaily reduced lung-function decline and acute exacerbations in patients \nwith...', 'thumbnail': 'https://serpapi.com/searches/67249e2d361fd472bcccbcd0/images/89581440c9f83602b217c95c344c46a41f180c3b7a039388918ded8f3da14987.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8697701692581177}","{'position': 2, 'link': 'https://lungdiseasenews.com/2017/10/26/ipf-therapy-ofev-shows-long-term-effectiveness-regardless-of-baseline-lung-function-early-analysis/', 'title': 'Early Analysis of Ofev in INPULSIS-ON Trial Shows Long-Term Effectiveness in Treating IPF', 'source': 'Lung Disease News', 'date': 'Oct 26, 2017', 'snippet': 'Read about how Ofev (nintedanib) was shown to slow down IPF progression \nregardless of baseline lung function in the Phase 3 INPULSIS...', 'thumbnail': 'https://serpapi.com/searches/67249e2d361fd472bcccbcd0/images/89581440c9f83602eed88dffc2b30f87abbda9c86e097ab0671a32977b535a02.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6172102093696594}","{'position': 3, 'link': 'https://pulmonaryfibrosisnews.com/news/ofev-effective-elderly-patients-comorbidities-ipf-idiopathic-pulmonary-fibrosis/', 'title': 'Ofev Effective in Elderly IPF Patients, Those With Several Comorbidities', 'source': 'Pulmonary Fibrosis News', 'date': 'Apr 30, 2021', 'snippet': 'Study suggests Ofev can preserve lung function in older idiopathic \npulmonary fibrosis patients and those who have several other health...', 'thumbnail': 'https://serpapi.com/searches/67249e2d361fd472bcccbcd0/images/89581440c9f83602db6345265d4a4d0eb42b7dc7720aa8db6dbc4d36a3adca05.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7142563462257385}","{'position': 4, 'link': 'https://pulmonaryfibrosisnews.com/news/ipf-patients-live-longer-on-nintedanib-pooled-data-from-six-trials-show/', 'title': 'IPF Patients Live Longer on Ofev Compared with Placebo, Analysis Shows', 'source': 'Pulmonary Fibrosis News', 'date': 'Apr 16, 2019', 'snippet': 'Treatment with Ofev (nintedanib) can significantly extend the survival of \npatients with idiopathic pulmonary fibrosis (IPF), an analysis of pooled \ndata from...', 'thumbnail': 'https://serpapi.com/searches/67249e2d361fd472bcccbcd0/images/89581440c9f83602d746b3d3e1f920930c4281a6b13e96767c94c1f404e17b31.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.544462263584137}",,,,,,,"['neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT02983708,"{'position': 1, 'link': 'https://cerebralpalsynewstoday.com/2017/02/17/stimulating-production-certain-white-blood-cells-improve-cp-symptoms-children/', 'title': 'CP Symptoms in Children Improved by Stimulating Production of Certain White Blood Cells', 'source': 'Cerebral Palsy News Today', 'date': 'Feb 17, 2017', 'snippet': 'Read about a study suggesting that stimulating the production of certain \ntypes of white blood cells improves the development of the nervous...', 'thumbnail': 'https://serpapi.com/searches/67249e301397ba76bd3ea55d/images/77e23f186a555f200d3b96abe046b9fb8db85de2fa6b9142309ca4cbf26a4ad4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7238370180130005}",,,,,,,,,,['neutral'],neutral,1 NCT03902691,"{'position': 1, 'link': 'https://www.renalandurologynews.com/news/pegmolesatide-maintains-hemoglobin-in-patients-on-dialysis/', 'title': 'Pegmolesatide Maintains Hemoglobin in Patients on Dialysis', 'source': 'Renal and Urology News', 'date': 'Feb 20, 2024', 'snippet': 'This phase 3 trial is the first to assess the efficacy and safety of a \nnovel EPO-mimetic since the withdrawal of peginesatide from the...', 'thumbnail': 'https://serpapi.com/searches/67249a38544c496fb1cad798/images/901f531be0cec307a943ba41bd9dc5cb9195ccd4087b7505fe65604a6d66f5da.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8224786520004272}",,,,,,,,,,['neutral'],neutral,1 NCT05275400,"{'position': 1, 'link': 'https://www.endocrinologyadvisor.com/news/insulin-efsitora-alfa/', 'title': 'Insulin Efsitora Alfa Demonstrates Non-Inferior Glycemic Control in T2D', 'source': 'Endocrinology Advisor', 'date': '1 month ago', 'snippet': 'Treatment with once-weekly insulin efsitora alfa, compared with daily basal \ninsulins, effects non-inferior glycemic control and a similar safety \nprofile.', 'thumbnail': 'https://serpapi.com/searches/67249a3a360f4e87ed13a2ec/images/779fa01c471bce91d5509c5cd33a50bbd032e214c2ec31fe3292291a1fee7d32.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8644056916236877}",,,,,,,,,,['neutral'],neutral,1 NCT04227470,"{'position': 1, 'link': 'https://myastheniagravisnews.com/news/phase-2-trial-testing-batoclimab-for-mg-begins-dosing/', 'title': 'Phase 2 MG Trial Testing Batoclimab Begins Dosing', 'source': 'Myasthenia Gravis News', 'date': 'Oct 2, 2020', 'snippet': ""A Phase 2 clinical trial of Harbour BioMed's investigational therapy \nbatoclimab, also known as HBM9161, for myasthenia gravis (MG),..."", 'thumbnail': 'https://serpapi.com/searches/67249cde7e1d1ff6c37fd974/images/4912636f97f0d6b1840fa489f0c44af6a0214b47563f8716a946902fee0d8349.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9191279411315918}",,,,,,,,,,['neutral'],neutral,1 NCT04333914,"{'position': 1, 'link': 'https://www.nature.com/articles/s43018-020-00120-5', 'title': 'Determinants of the outcomes of patients with cancer infected with SARS-CoV-2: results from the Gustave Roussy cohort', 'source': 'Nature', 'date': 'Sep 22, 2020', 'snippet': 'Patients with cancer are presumed to be at increased risk of severe \nCOVID-19 outcomes due to underlying malignancy and treatment-induced \nimmunosuppression.', 'thumbnail': 'https://serpapi.com/searches/67249d91e10f0a1c7374cbdb/images/6eb29f499cbdfbd9259d90b8855ef74a8a029206207c62cdff67199f9c06191d.png', 'sentiment': 'negative', 'sentiment_prob': 0.5159276723861694}",,,,,,,,,,['negative'],negative,0 NCT03525444,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/news/benefits-trikafta-cf-sustained-3-5-years-extension-trial/', 'title': 'Benefits of Trikafta for CF sustained 3.5+ years in extension trial', 'source': 'Cystic Fibrosis News Today', 'date': 'Jun 14, 2023', 'snippet': 'Long-term treatment with Trikafta leads to sustained lung function gains, \neasing of respiratory symptoms, and better nutritional status.', 'thumbnail': 'https://serpapi.com/searches/67249dc2d0253e868c227f5f/images/95ba711df3d6880394cb3fcb67c678a40ecc49feab6ca31ff9b225629b35c408.png', 'sentiment': 'positive', 'sentiment_prob': 0.8928873538970947}","{'position': 2, 'link': 'https://cysticfibrosisnewstoday.com/news/northern-ireland-reaches-deal-with-vertex-for-access-to-kaftrio/', 'title': 'CF Drug Kaftrio Will be Available in Northern Ireland After Deal With Vertex', 'source': 'Cystic Fibrosis News Today', 'date': 'Aug 3, 2020', 'snippet': 'Northern Ireland reached a deal with Vertex Pharmaceuticals to make Kaftrio \navailable for treating cystic fibrosis, once the drug gets its...', 'thumbnail': 'https://serpapi.com/searches/67249dc2d0253e868c227f5f/images/95ba711df3d68803a692995aef7a8186c53fe0311e73fd810ecdd5cb4266bdc5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7986085414886475}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT00128453,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1208536', 'title': 'A Randomized Trial of Colchicine for Acute Pericarditis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 1, 2013', 'snippet': 'Colchicine is effective for the treatment of recurrent pericarditis. \nHowever, conclusive data are lacking regarding the use of colchicine...', 'thumbnail': 'https://serpapi.com/searches/67249dcad403e1b06e08e8c5/images/458fdfec58e1d25f29b1002fd42201fa5780e57ea84ac4c57bf08bfd74234ce3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8339667320251465}",,,,,,,,,,['neutral'],neutral,1 NCT03823300,"{'position': 1, 'link': 'https://www.globenewswire.com/news-release/2023/04/25/2654401/0/en/New-Vabysmo-data-suggest-greater-retinal-drying-versus-aflibercept-in-nAMD-and-DME.html', 'title': 'New Vabysmo data suggest greater retinal drying versus aflibercept in nAMD and DME', 'source': 'GlobeNewswire', 'date': 'Apr 25, 2023', 'snippet': ""Post-hoc analyses from four phase III studies indicate Vabysmo dried \nretinal fluid faster with fewer injections in neovascular or 'wet'..."", 'thumbnail': 'https://serpapi.com/searches/67249dee17b10ef88bd2d293/images/492be2dc7853d7323deb8cd06087794cff13b4456461d5eb4527fced68299c29.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8941206932067871}",,,,,,,,,,['neutral'],neutral,1 NCT02799602,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/time-to-progression-in-mhspc-cohort-prolonged-with-darolutamide', 'title': 'Time to Progression in mHSPC Cohort Prolonged With Darolutamide', 'source': 'Cancer Network', 'date': 'Jun 3, 2024', 'snippet': 'The rate of subsequent anticancer therapy was reduced with darolutamide vs \nplacebo in patients with mHSPC in the ARASENS trial.', 'thumbnail': 'https://serpapi.com/searches/67249df24a4a1d3f6d810b5d/images/59aeb2ad75caf7e1001c293ba123d736d6fa0c842beb267e96c89dddb665a7bf.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.840165913105011}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2119115', 'title': 'Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'Feb 17, 2022', 'snippet': 'Darolutamide is a potent androgen-receptor inhibitor that has been \nassociated with increased overall survival among patients with \nnonmetastatic, castration-...', 'thumbnail': 'https://serpapi.com/searches/67249df24a4a1d3f6d810b5d/images/59aeb2ad75caf7e133b9a0107f675eadb331609c220bba681890150f68d1de7f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7056580781936646}","{'position': 3, 'link': 'https://www.urologytimes.com/view/os-benefit-with-darolutamide-maintained-throughout-mhspc-treatment-course', 'title': 'OS benefit with darolutamide maintained throughout mHSPC treatment course', 'source': 'Urology Times', 'date': 'Feb 19, 2024', 'snippet': '""Post-hoc sensitivity analyses from the phase 3 ARASENS trial presented at \nASCO GU were consistent with and supportive of the ARASENS...', 'thumbnail': 'https://serpapi.com/searches/67249df24a4a1d3f6d810b5d/images/59aeb2ad75caf7e124c7fcd9b04c6e44544fb102b2a39ffb3960a0cb311f4bf2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5970762968063354}","{'position': 4, 'link': 'https://www.cancernetwork.com/view/darolutamide-plus-adt-and-docetaxel-improves-quality-of-life-vs-placebo-in-mhspc', 'title': 'Darolutamide Plus ADT and Docetaxel Improves Quality of Life Vs Placebo in mHSPC', 'source': 'Cancer Network', 'date': 'Oct 31, 2022', 'snippet': 'Quality of life data from the phase 3 ARASENS study highlighted how early \ntreatment intensification with darolutamide plus standard androgen...', 'thumbnail': 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New England Journal of Medicine', 'date': 'Jan 25, 2023', 'snippet': 'Participants who had received three doses of BNT162b2 vaccine received \neither a fourth dose or a bivalent vaccine containing BA.4–BA.5 mRNA;...', 'thumbnail': 'https://serpapi.com/searches/67249bb8f7adbf728190c3a5/images/2c6990faf3ac8d02869f496bfd1a908d367c0fb2046e285c4f560a5a9ca1e129.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9136152863502502}",,,,,,,,,,['neutral'],neutral,1 NCT01611090,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-018-0276-9', 'title': 'Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine, and rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma', 'source': 'Nature', 'date': 'Oct 12, 2018', 'snippet': 'We report follow-up results from the randomized, placebo-controlled, phase \n3 HELIOS trial of ibrutinib+bendamustine and rituximab (BR) for...', 'thumbnail': 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showcase improved survival vs placebo when used as an adjuvant \ntreatment in...', 'thumbnail': 'https://serpapi.com/searches/67249bd935853954fd9f3fbd/images/4c260aae3a0668cd890d670e28d39b899d71cb397a21d6bb77735f6abcb20334.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6742091774940491}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01345019,"{'position': 1, 'link': 'https://myelomaresearchnews.com/xgeva-denosumab/', 'title': 'XGEVA (Denosumab)', 'source': 'Myeloma Research News', 'date': 'Feb 9, 2018', 'snippet': 'Xgeva (denosumab) was approved by the US Food and Drug Administration (FDA) \nto treat bone problems (skeletal-related events) in multiple myeloma (MM) \npatients.', 'thumbnail': 'https://serpapi.com/searches/67249be2e10f0a1c4155b9c2/images/411fce72dfd312d7e879564f2c62edf1d7a587e2d64875b2dc09c19ada39bb9a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7067121267318726}","{'position': 2, 'link': 'https://myelomaresearchnews.com/news/fda-approves-xgeva-to-treat-myeloma-patients-with-bone-lesions/', 'title': 'FDA Extends Xgeva Approval to Include Myeloma Patients with Bone Lesions', 'source': 'Myeloma Research News', 'date': 'Jan 8, 2018', 'snippet': ""The U.S. Food and Drug Administration (FDA) has agreed to extend Xgeva's \n(denosumab) approval to include patients with multiple myeloma who..."", 'thumbnail': 'https://serpapi.com/searches/67249be2e10f0a1c4155b9c2/images/411fce72dfd312d737f0849400b23a054f6239e72ea08e109674c9dadf95a629.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8024888038635254}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT00262600,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa0905561', 'title': 'Dabigatran versus Warfarin in Patients with Atrial Fibrillation', 'source': 'The New England Journal of Medicine', 'date': 'Aug 30, 2009', 'snippet': 'Dabigatran administered at a dose of 150 mg, as compared with warfarin, was \nassociated with lower rates of stroke and systemic embolism but similar \nrates of...', 'thumbnail': 'https://serpapi.com/searches/67249c9064f11d5673dda938/images/ba016c2223ab9a0aecd0a9e2f7b4c9e3ffd80940b086707ced70218ab5cc8efa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8747334480285645}",,,,,,,,,,['neutral'],neutral,1 NCT02207231,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1501646', 'title': 'A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis', 'source': 'The New England Journal of Medicine', 'date': 'Jul 9, 2015', 'snippet': 'Little is known about the effect of specific anti–interleukin-23 therapy, \nas compared with established anti–tumor necrosis factor therapies,...', 'thumbnail': 'https://serpapi.com/searches/67249c93e10f0a1c7374cb8d/images/0d38a4393f609d871372e816bfcbd2a5d7810dddd43e6611d088960c41a0cc14.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7835938930511475}","{'position': 2, 'link': 'https://psoriasisnewstoday.com/2017/05/25/janssens-phase-3-trials-on-guselkumab-for-plaque-psoriasis-and-psoriatic-arthritis/', 'title': 'Janssen’s Phase 3 Trials for Guselkumab to Focus on Plaque Psoriasis, Psoriatic Arthritis', 'source': 'Psoriasis News Today', 'date': 'May 25, 2017', 'snippet': 'Janssen announced two new Phase 3 clinical trials for psoriasis for its \ninvestigational drug guselkumab. The company intends to explore the...', 'thumbnail': 'https://serpapi.com/searches/67249c93e10f0a1c7374cb8d/images/0d38a4393f609d87a16edb53221fbeb7f625e56788d090228cd815c7cf91e15f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9209516644477844}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT02519322,"{'position': 1, 'link': 'https://www.nature.com/articles/s41586-022-05368-8', 'title': 'Neoadjuvant relatlimab and nivolumab in resectable melanoma', 'source': 'Nature', 'date': '٢٦\u200f/١٠\u200f/٢٠٢٢', 'snippet': 'Relatlimab and nivolumab combination immunotherapy improves \nprogression-free survival over nivolumab monotherapy in patients with \nunresectable advanced...', 'thumbnail': 'https://serpapi.com/searches/67249c9eee677f09ee97d9c6/images/569fafb0bd32c3795b160742ad0465b5a8132881999a5df04e57ec148fe39e22.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7452478408813477}",,,,,,,,,,['neutral'],neutral,1 NCT01673009,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-020-0903-x', 'title': 'Translating current basic research into future therapies for neurofibromatosis type 1', 'source': 'Nature', 'date': 'May 22, 2020', 'snippet': 'Neurofibromatosis type 1 (NF1) is a hereditary tumour syndrome that \npredisposes to benign and malignant tumours originating from neural...', 'thumbnail': 'https://serpapi.com/searches/67249b4a163bdfc2e8bebf0f/images/ae327f0f085cefa4b548574a3f1c546e5d26ca7cdbd0e54cd77b6fb6744967b5.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.803081214427948}",,,,,,,,,,['neutral'],neutral,1 NCT00871910,"{'position': 1, 'link': 'https://www.nature.com/articles/bjc2017288', 'title': 'Phase 1 safety, pharmacokinetic and pharmacodynamic study of the cyclin-dependent kinase inhibitor dinaciclib administered every three weeks in patients with advanced malignancies', 'source': 'Nature', 'date': 'Aug 31, 2017', 'snippet': 'Dinaciclib is a potent inhibitor of cell cycle and transcriptional \ncyclin-dependent kinases. This Phase 1 study evaluated the safety,...', 'thumbnail': 'https://serpapi.com/searches/67249a7698876d3da3da3360/images/ee2816685608698886f5b4e16b90064af11a2c3192a4915d8c119364ac21fe09.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8695429563522339}",,,,,,,,,,['neutral'],neutral,1 NCT00772538,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1208606', 'title': 'Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy', 'source': 'The New England Journal of Medicine', 'date': 'Sep 3, 2012', 'snippet': 'In two replicate, randomized, controlled trials involving 912 patients with \nasthma who were receiving inhaled glucocorticoids and LABAs,...', 'thumbnail': 'https://serpapi.com/searches/67249a7bd9c3e6ccf76a19c9/images/c1de719ce73f96cc17246e8a1aaa4f4a5421e287edd111c643783422334878d1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5179815888404846}",,,,,,,,,,['neutral'],neutral,1 NCT02576509,"{'position': 1, 'link': 'https://www.mayoclinicproceedings.org/article/S0025-6196(18)30002-8/fulltext', 'title': 'Multiple Cranial Neuropathies From Nivolumab in a Patient With Metastatic Hepatocellular Carcinoma', 'source': 'Mayo Clinic Proceedings', 'date': 'Apr 30, 2018', 'snippet': 'Nivolumab is a checkpoint inhibitor immunotherapy with multiple clinical \nindications. Based on encouraging activity from a phase 1/2 single-arm \nstudy,.', 'thumbnail': 'https://serpapi.com/searches/67249aa4ec54104fb652dbfa/images/ec651a09b604949821ebcaca1832a95597b3e2883f284235ba4468c0c36bcb94.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9014251828193665}",,,,,,,,,,['neutral'],neutral,1 NCT04871737,"{'position': 1, 'link': 'https://www.mountsinai.org/about/newsroom/2023/castlevax-inc-receives-barda-project-nextgen-award-valued-at-up-to-three-hundred-thirty-eight-million-to-advance-intranasal-ndvbased-covid-booster-vaccine-into-phase-twob-clinical-efficacy-testing', 'title': 'CastleVax Inc. Receives BARDA Project NextGen Award Valued at up to $338 Million to Advance Intranasal NDV-based COVID-19 Booster Vaccine into Phase 2b Clinical Efficacy Testing', 'source': 'Mount Sinai', 'date': 'Oct 17, 2023', 'snippet': 'CastleVax, a clinical stage vaccine platform company, has received a \nProject NexGen award valued at up to $338 million from the Biomedical...', 'thumbnail': 'https://serpapi.com/searches/67249adfe9b691b4208dc4bd/images/48842c8136046263d54ac00fb74280d547215837c9088244cc1bf206baa007c7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7130514979362488}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20240730713002/en/CastleVax-Inc.-Receives-34-Million-from-BARDA-to-Continue-Advancing-Intranasal-NDV-based-COVID-19-Vaccine-into-Phase-2b-Clinical-Efficacy-Testing', 'title': 'CastleVax Inc. Receives $34 Million from BARDA to Continue Advancing Intranasal NDV-based COVID-19 Vaccine into Phase 2b Clinical Efficacy Testing', 'source': 'Business Wire', 'date': 'Jul 30, 2024', 'snippet': 'CastleVax, a clinical stage mucosal vaccine platform company, has received \nan additional Project NextGen award valued at approximately $34...', 'thumbnail': 'https://serpapi.com/searches/67249adfe9b691b4208dc4bd/images/48842c813604626399fd67a2af9d857d165b68393819c0641cdd1c99ff84d869.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6780118346214294}","{'position': 3, 'link': 'https://www.mountsinai.org/about/newsroom/2022/mount-sinai-announces-the-formation-of-castlevax-inc-a-clinical-stage-infectious-diseases-company-developing-novel-vaccines-and-therapeutics-targeting-pandemic-threats-and-diseases-of-unmet-medical-need', 'title': 'Mount Sinai Announces the Formation of CastleVax Inc., a Clinical-Stage Infectious Diseases Company Developing Novel Vaccines and Therapeutics, Targeting Pandemic Threats and Diseases of Unmet Medical Need', 'source': 'Mount Sinai', 'date': 'Aug 9, 2022', 'snippet': 'The Mount Sinai Health System in New York, NY, has launched CastleVax, Inc. \n(CastleVax), a clinical-stage vaccine research and development company.', 'thumbnail': 'https://serpapi.com/searches/67249adfe9b691b4208dc4bd/images/48842c813604626325529b99be7fb0c8213e2f5120933693c74d3594492f2693.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8842910528182983}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT01296932,"{'position': 1, 'link': 'https://www.nature.com/articles/s41375-019-0475-z', 'title': 'Phase 1 first-in-human trial of the anti-CD37 antibody BI 836826 in relapsed/refractory chronic lymphocytic leukemia', 'source': 'Nature', 'date': 'May 14, 2019', 'snippet': 'Chronic lymphocytic leukemia (CLL) remains incurable for most patients, \nrequiring repeated therapy [1]. The tetraspanin CD37 is...', 'thumbnail': 'https://serpapi.com/searches/67249ae017b10ef85e9c1e3c/images/3769faf858e5b1a376f63fd13f623268f80e5f645df0e8ad562a833a18c8a667.png', 'sentiment': 'negative', 'sentiment_prob': 0.5485190749168396}",,,,,,,,,,['negative'],negative,0 NCT03165617,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2024848', 'title': 'Efficacy of a Cell-Culture–Derived Quadrivalent Influenza Vaccine in Children', 'source': 'The New England Journal of Medicine', 'date': 'Oct 13, 2021', 'snippet': 'Cell-culture–derived influenza vaccines may enable a closer antigenic match \nto circulating strains of influenza virus by avoiding...', 'thumbnail': 'https://serpapi.com/searches/67249ae2b4fe87984be9a68c/images/b48255bb5fd8ca8c42fd9d84fb90b3cb66212463894a4917794c56684eb1fb2c.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8928518891334534}",,,,,,,,,,['neutral'],neutral,1 NCT04349072,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062534', 'title': 'Dose-Blinded Myosin Inhibition in Patients With Obstructive Hypertrophic Cardiomyopathy Referred for Septal Reduction Therapy: Outcomes Through 32 Weeks | Circulation', 'source': 'American Heart Association Journals', 'date': 'Nov 6, 2022', 'snippet': '32 weeks of mavacamten treatment showed sustained reduction in the \nproportion proceeding to SRT or remaining guideline eligible, with similar \neffects observed...', 'thumbnail': 'https://serpapi.com/searches/67249ae5a47167925e857d6f/images/68e5bf3613a37b4e771987d9a01bf7f155fdb4b8563b57b7924d891472bc462b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8345443606376648}",,,,,,,,,,['neutral'],neutral,1 NCT02277769,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1610020', 'title': 'Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis', 'source': 'The New England Journal of Medicine', 'date': 'Oct 1, 2016', 'snippet': 'In two randomized, placebo-controlled, phase 3 trials of identical design \n(SOLO 1 and SOLO 2), we enrolled adults with moderate-to-severe...', 'thumbnail': 'https://serpapi.com/searches/67249c0020e6eb1defbc3545/images/20bd83cfea45195768c31149a6b3613a7f8b0eaac63a09da889bdce3316b92e6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8945711851119995}","{'position': 2, 'link': 'https://www.dermatologytimes.com/view/when-to-progress-to-systemic-therapy', 'title': 'When to Progress to Systemic Therapy', 'source': 'Dermatology Times', 'date': 'Aug 11, 2022', 'snippet': 'This is an exciting time for offering safe and effective novel therapies to \npatients with moderate-to-severe AD who are inadequately controlled with \ntopical...', 'thumbnail': 'https://serpapi.com/searches/67249c0020e6eb1defbc3545/images/20bd83cfea451957eb4af8ae4ea76b542f7adbf08a9186e137cb832e4720ddf5.png', 'sentiment': 'positive', 'sentiment_prob': 0.7247567772865295}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04308681,"{'position': 1, 'link': 'https://pulmonaryfibrosisnews.com/news/ipf-lung-function-decline-may-slow-with-lpa1-antagonist-bms-986278/', 'title': 'IPF lung function decline may slow with LPA1 antagonist BMS-986278...', 'source': 'Pulmonary Fibrosis News', 'date': 'May 26, 2023', 'snippet': 'BMS-986278 did better than a placebo at slowing lung function decline for \nup to 26 weeks in people with idiopathic pulmonary fibrosis.', 'thumbnail': 'https://serpapi.com/searches/67249c0a9819f30f3cbfcfd4/images/48bc97cdf3cf4ffc08914448ef02f9ed4192cf804e6723d1925601970ebc1736.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6781575083732605}","{'position': 2, 'link': 'https://pulmonaryfibrosisnews.com/news/bms-986278-slows-lung-function-decline-progressive-pf-trial/', 'title': 'Oral BMS-986278 slows lung decline in progressive PF, Phase 2 trial finds', 'source': 'Pulmonary Fibrosis News', 'date': 'Sep 25, 2023', 'snippet': 'The experimental oral therapy BMS-986278, taken at 60 mg twice daily for 26 \nweeks, resulted in a 69% reduction in the rate of lung function decline in \nadults...', 'thumbnail': 'https://serpapi.com/searches/67249c0a9819f30f3cbfcfd4/images/48bc97cdf3cf4ffcf87584e47b16d363c8bf3ab199b81c941dd77311ad7544be.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8356699347496033}","{'position': 3, 'link': 'https://pulmonaryfibrosisnews.com/news/bms-986278-breakthrough-therapy-status-progressive-pf/', 'title': 'BMS-986278 earns breakthrough therapy status for progressive PF', 'source': 'Pulmonary Fibrosis News', 'date': 'Oct 27, 2023', 'snippet': ""The U.S. Food and Drug Administration has granted Bristol Myers Squibb's \ninvestigational therapy BMS-986278 breakthrough therapy status."", 'thumbnail': 'https://serpapi.com/searches/67249c0a9819f30f3cbfcfd4/images/48bc97cdf3cf4ffc24ad930768a120bdd93402ff379a93b5622fb5fbadca2736.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5977893471717834}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT04776317,"{'position': 1, 'link': 'https://newsroom.uw.edu/news-releases/second-generation-covid-19-vaccine-clinical-trial-starts', 'title': 'Second-generation COVID-19 vaccine clinical trial starts', 'source': 'UW Medicine | Newsroom', 'date': 'Nov 28, 2023', 'snippet': 'Phase 1 clinical trial at UW Medicine will determine safety, tolerability, \nand immune response to Gritstone experimental vaccine candidate.', 'thumbnail': 'https://serpapi.com/searches/67249c22642c31cda3d5d0dc/images/6bce4b3cf480d129fa94138c543de7378842021a2ddc4e3c476adeb338152f20.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9083326458930969}","{'position': 2, 'link': 'https://www.nature.com/articles/s41591-022-01937-6', 'title': 'Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results', 'source': 'Nature', 'date': 'Aug 15, 2022', 'snippet': 'Checkpoint inhibitor (CPI) therapies provide limited benefit to patients \nwith tumors of low immune reactivity. T cell-inducing vaccines hold...', 'thumbnail': 'https://serpapi.com/searches/67249c22642c31cda3d5d0dc/images/6bce4b3cf480d129679f05a9c9837b1755867037f167f4b9c1ba7053ef95196a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.547188937664032}","{'position': 3, 'link': 'https://newsroom.uw.edu/news-releases/ongoing-booster-vaccine-trial-seeks-vaccinated-volunteers', 'title': 'Ongoing booster vaccine trial seeks vaccinated volunteers', 'source': 'UW Medicine | Newsroom', 'date': 'Nov 28, 2023', 'snippet': 'Researchers are still enrolling study participants who have not already \nreceived a vaccine booster against SARS-CoV-2.', 'thumbnail': 'https://serpapi.com/searches/67249c22642c31cda3d5d0dc/images/6bce4b3cf480d1295a9a91420f6773b553d47611d930d6480af753a3d973ec87.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8936087489128113}","{'position': 4, 'link': 'https://newsroom.uw.edu/news-releases/next-generation-covid-19-vaccine-trial-seeks-volunteers', 'title': '2nd-generation COVID-19 vaccine trial seeks volunteers', 'source': 'UW Medicine | Newsroom', 'date': 'Nov 28, 2023', 'snippet': 'This study is recruiting COVID-19-vaccinated and boosted persons interested \nin receiving additional investigational vaccination against SARS-CoV-2.', 'thumbnail': 'https://serpapi.com/searches/67249c22642c31cda3d5d0dc/images/6bce4b3cf480d129ce4b6cbde380a00c098b4ef1c78eba162eeb68dfe6200bff.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.861581027507782}",,,,,,,"['neutral', 'negative', 'neutral', 'neutral']",neutral,1 NCT01290939,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1707358', 'title': 'Lomustine and Bevacizumab in Progressive Glioblastoma', 'source': 'The New England Journal of Medicine', 'date': 'Nov 16, 2017', 'snippet': 'Treatment with lomustine plus bevacizumab did not confer a survival \nadvantage over treatment with lomustine alone in patients with progressive \nglioblastoma.', 'thumbnail': 'https://serpapi.com/searches/67249c4cd0d7e3608f18697e/images/533484bd3c643681dae573320faa13a2e4fbfd423a8357f6949b48247fff874d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.49823349714279175}",,,,,,,,,,['neutral'],neutral,1 NCT03187678,"{'position': 1, 'link': 'https://www.empr.com/home/news/uptravi-selexipag-injection-approved-for-pulmonary-arterial-hypertension/', 'title': 'FDA Approves IV Formulation of Uptravi for Pulmonary Arterial Hypertension', 'source': 'Medical Professionals Reference', 'date': 'Aug 2, 2021', 'snippet': 'The Food and Drug Administration (FDA) has approved Uptravi® (selexipag) \ninjection for intravenous (IV) use for the treatment of pulmonary...', 'thumbnail': 'https://serpapi.com/searches/67249c6e7ef9fadce9afafdd/images/4e85d697be074fa08776e56250f8f749b5090abf051d53361fed8e64bc8d1ee0.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8002889752388}",,,,,,,,,,['neutral'],neutral,1 NCT01492361,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1812792', 'title': 'Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia', 'source': 'The New England Journal of Medicine', 'date': 'Nov 12, 2018', 'snippet': 'We performed a multicenter, randomized, double-blind, placebo-controlled \ntrial involving patients with established cardiovascular disease or...', 'thumbnail': 'https://serpapi.com/searches/67249c70bcd65263817dbca4/images/b4ceba36cc923b07f58045d231a09c3b664102fc4740fd9b2fc8a1fb0f9d8d3a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8963292837142944}",,,,,,,,,,['neutral'],neutral,1 NCT03356821,"{'position': 1, 'link': 'https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(22)00117-X/abstract', 'title': 'Feasibility and safety of intranasally administered mesenchymal stromal cells after perinatal arterial ischaemic stroke in the Netherlands (PASSIoN): a first-in-human, open-label intervention study', 'source': 'The Lancet', 'date': 'Oct 3, 2022', 'snippet': 'Perinatal arterial ischaemic stroke (PAIS) is an important cause of \nneurodevelopmental disabilities. 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Zuranolone is a neuroactive steroid \ngamma-aminobutyric acid...', 'thumbnail': 'https://serpapi.com/searches/67249cfab2ebae2669c54b10/images/f1ff91119e50a5d681bad23fc47ab52e322009d802c73c2ad95b1673bc934acd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.879035234451294}",,,,,,,,"['neutral', 'negative', 'neutral']",neutral,1 NCT02240407,"{'position': 1, 'link': 'https://pompediseasenews.com/raav9-des-hgaa/', 'title': 'rAAV9-DES-hGAA for Pompe disease', 'source': 'Pompe Disease News', 'date': 'Jun 26, 2023', 'snippet': 'An experimental gene therapy, meaning it replaces a faulty gene with a \nhealthy one, rAAV9-DES-hGAA has been tested in clinical trials as a \ntreatment for Pompe...', 'thumbnail': 'https://serpapi.com/searches/67249d0a2e33c879f5aecdbc/images/5cb6795d72bb3df0b48e2ead3e0c259ce4e24d2512f275b48ff5cde404d879e3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7026476860046387}",,,,,,,,,,['neutral'],neutral,1 NCT03174184,"{'position': 1, 'link': 'https://www.infectiousdiseaseadvisor.com/news/meropenem-plus-clavulanate-and-rifampin-treatment-drug-resistant-tuberculosis-tb/', 'title': 'Meropenem Plus Clavulanate and Rifampin for Treatment of Drug-Resistant TB', 'source': 'Infectious Disease Advisor', 'date': 'Mar 29, 2022', 'snippet': 'A clinical trial found that intravenous meropenem plus \namoxicillin/clavulanate, while effective at certain doses, is poorly \ntolerated by...', 'thumbnail': 'https://serpapi.com/searches/67249d1d8d041735fe1ce5c2/images/169be0b84645f1e9bb85644e029aaf1a500f3f6c07498181d34943d68172dfc1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.563075840473175}",,,,,,,,,,['neutral'],neutral,1 NCT00537147,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMp2301816', 'title': 'Combating West Nile Virus Disease — Time to Revisit Vaccination', 'source': 'The New England Journal of Medicine', 'date': 'Apr 29, 2023', 'snippet': 'WNV remains a public health threat in many areas of the world, and current \napproaches to primary prevention have limitations.', 'thumbnail': 'https://serpapi.com/searches/67249d3771c62bd52d0da5aa/images/91397909a0b339a4e6b463fe6bcefb3c80e675c60ca1590c3aec4965c4329de9.png', 'sentiment': 'negative', 'sentiment_prob': 0.7227003574371338}",,,,,,,,,,['negative'],negative,0 NCT00094302,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.12660', 'title': 'Variation in clinical and patient-reported outcomes among complex heart failure with preserved ejection fraction phenotypes', 'source': 'Wiley Online Library', 'date': 'Mar 11, 2020', 'snippet': 'Aims The aim of this study is to use six previously described heart failure \nwith preserved ejection fraction (HFpEF) phenotypes to describe...', 'thumbnail': 'https://serpapi.com/searches/67249d6a1f3d4bc29b7b350e/images/3b6cdcacf2d9e2237c4d540e36619aa472da15f654f2e8b2f9dd9de7c0e85970.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9017375111579895}",,,,,,,,,,['neutral'],neutral,1 NCT03928704,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2024/09/30/bimekizumab-bimzelx-wins-fda-approval-of-active-as-nr-axspa/', 'title': 'FDA approves bimekizumab, now Bimzelx, for active AS and nr-axSpA', 'source': 'Ankylosing Spondylitis News', 'date': '1 month ago', 'snippet': ""Data from two Phase 3 clinical trials, BE MOBILE 1 and BE MOBILE 2, \nsupported Bimzelx's approvals for active nr-axSpA and AS."", 'thumbnail': 'https://serpapi.com/searches/67249e83cf32e043b585fadc/images/760bd9b439a4c11830f5a026026930f38cfa4a1b22ee4e8bd9024531235a1d17.png', 'sentiment': 'neutral', 'sentiment_prob': 0.694316565990448}",,,,,,,,,,['neutral'],neutral,1 NCT01494506,"{'position': 1, 'link': 'https://www.researchgate.net/figure/NAPOLI-1-and-exploratory-post-hoc-analysis-patient-disposition-flow-diagram_fig1_347280190', 'title': 'NAPOLI-1 and exploratory post hoc analysis: patient disposition flow diagram.', 'source': 'ResearchGate', 'date': 'Mar 5, 2021', 'snippet': 'Background Chemotherapy dose modification to manage adverse events is \ncommonplace in clinical practice. This exploratory analysis evaluates the \nimpact of...', 'thumbnail': 'https://serpapi.com/searches/67249faa2a4882ac457455f0/images/520bc3e7afa7ec9483829c967f3133e9f312c3b21ca032d910443413606ac152.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9004329442977905}",,,,,,,,,,['neutral'],neutral,1 NCT02999178,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1908681', 'title': 'Nintedanib in Progressive Fibrosing Interstitial Lung Diseases', 'source': 'The New England Journal of Medicine', 'date': 'Sep 29, 2019', 'snippet': 'Preclinical data have suggested that nintedanib, an intracellular inhibitor \nof tyrosine kinases, inhibits processes involved in the progression of \nlung...', 'thumbnail': 'https://serpapi.com/searches/67249fc5f79a01079bee74f2/images/c5d2fd340c973e500f5c6c1d244347c287e2abc9eec468f4ccb318880bd95ba9.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8144998550415039}","{'position': 2, 'link': 'https://lungdiseasenews.com/2017/03/28/phase-3-study-of-ofev-in-progressive-fibrosing-lung-diseases-enrolling-patients/', 'title': ""Ofev's Efficacy to Be Tested in Progressive Fibrosing Lung Disease Patients in Phase 3 Study"", 'source': 'Lung Disease News', 'date': 'Mar 28, 2017', 'snippet': ""The first patient has been enrolled in Boehringer Ingelheim's Phase 3 \nclinical trial investigating the effectiveness and safety of Ofev..."", 'thumbnail': 'https://serpapi.com/searches/67249fc5f79a01079bee74f2/images/c5d2fd340c973e50aeeeecd0e09331768ddef7e0ee406c2308cdf6f33e3c6ccc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.878416895866394}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03164603,"{'position': 1, 'link': 'https://www.nature.com/articles/s41416-019-0664-6', 'title': 'The therapeutic potential of targeting tryptophan catabolism in cancer', 'source': 'Nature', 'date': 'Dec 10, 2019', 'snippet': 'Based on its effects on both tumour cell intrinsic malignant properties as \nwell as anti-tumour immune responses, tryptophan catabolism has...', 'thumbnail': 'https://serpapi.com/searches/67249ed09936886f64d2e40d/images/61aa2d0b192a62bcec626ae557cf0a217d08d05b3e715d702fccea83ff787f56.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7628021240234375}",,,,,,,,,,['neutral'],neutral,1 NCT03093324,"{'position': 1, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2021/04/13/vumerity-better-quality-of-life-than-tecfidera-for-patients-evolve-ms-2-study/', 'title': 'Vumerity Linked to Better Quality of Life Than Tecfidera in RRMS Trial', 'source': 'Multiple Sclerosis News Today', 'date': 'Apr 13, 2021', 'snippet': 'Vumerity (diroximel fumarate) is easier on the gastrointestinal tract than \nTecfidera (dimethyl fumarate), and this translates into better quality of \nlife for...', 'thumbnail': 'https://serpapi.com/searches/67249f39b4fe87984be9a844/images/6a93be02ed229c6e3cf75212311ae406595f87aceb2b4c3c016b07a2b6f26bbb.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6973385810852051}",,,,,,,,,,['positive'],positive,1 NCT04889209,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2116414', 'title': 'Homologous and Heterologous Covid-19 Booster Vaccinations', 'source': 'The New England Journal of Medicine', 'date': 'Jan 26, 2022', 'snippet': 'Although the three vaccines against coronavirus disease 2019 (Covid-19) \nthat have received emergency use authorization in the United States...', 'thumbnail': 'https://serpapi.com/searches/67249f3ca505f7b93bf4348a/images/c610d6262f148407fc6e70c33c76f59f34f6433e9357fd50c6771c68e42f1623.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8153026103973389}",,,,,,,,,,['neutral'],neutral,1 NCT04533022,"{'position': 1, 'link': 'https://pulmonaryfibrosisnews.com/news/vicore-nippon-reach-285m-deal-ipf-treatment-c21-rights-japan/', 'title': 'Nippon awarded exclusive rights in Japan to IPF treatment C21', 'source': 'Pulmonary Fibrosis News', 'date': 'Feb 23, 2024', 'snippet': 'In a deal that could be worth up to $285 million, Vicore Pharma granted \nNippon Shinyaku exclusive rights in Japan to its IPF treatment C21.', 'thumbnail': 'https://serpapi.com/searches/67249f44bd7cf05235f5ad98/images/6a49a15327b76f9d4462756a430d3eda59ef6ea1bb66bcc72f364b12eddf7400.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8054866194725037}",,,,,,,,,,['neutral'],neutral,1 NCT05924243,"{'position': 1, 'link': 'https://www.apdaparkinson.org/article/new-parkinsons-treatment-in-clinical-trials-2023/', 'title': 'New Parkinson’s Treatments in the Clinical Trial Pipeline for 2024', 'source': 'American Parkinson Disease Association', 'date': 'Sep 26, 2023', 'snippet': ""Extensive research is underway to develop new medications for Parkinson's \ndisease (PD), with several promising candidates at different..."", 'thumbnail': 'https://serpapi.com/searches/67249f4924296ac7f50bb3db/images/1160d4fefd9761b0bbb196420af1fc5ec796ff5a78f6ebbf3cb9e6c73fed6168.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5578852891921997}",,,,,,,,,,['positive'],positive,1 NCT02726581,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/safety-concerns-prompt-fda-to-put-a-hold-on-opdivo-combination-trials-for-myeloma/', 'title': '3 Myeloma Trials of Opdivo Put on Hold Due to Safety Concerns Over Other Therapies', 'source': 'Myeloma Research News', 'date': 'Sep 8, 2017', 'snippet': 'The US Food and Drug Administration has ordered Bristol-Myers Squibb to put \na hold on three clinical trials evaluating Opdivo (nivolumab) in \ncombination with...', 'thumbnail': 'https://serpapi.com/searches/6724a1e7bbc18b33ac2dc1b8/images/d605b0a71ba3e2ace2d67f53236bcc5ba5a400af4d26b88cc41e592734959589.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7855069041252136}",,,,,,,,,,['neutral'],neutral,1 NCT04968574,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20240501177434/en/Endeavor-BioMedicines-to-Present-New-Data-From-Phase-2a-Clinical-Trial-of-ENV-101-at-American-Thoracic-Society-2024-International-Conference', 'title': 'Endeavor BioMedicines to Present New Data From Phase 2a Clinical Trial of ENV-101 at American Thoracic Society 2024 International Conference', 'source': 'Business Wire', 'date': 'May 1, 2024', 'snippet': ""Data from a completed Phase 2a clinical trial evaluating the company's lead \ninvestigational candidate ENV-101 in patients with idiopathic pulmonary \nfibrosis (..."", 'thumbnail': 'https://serpapi.com/searches/6724a1eb68831e63a4ce34e2/images/c6f52aa8cd5f79f056adf19dcc17169042894d73892dfb23153e5d3b1ef0481a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.886804461479187}","{'position': 2, 'link': 'https://pulmonaryfibrosisnews.com/news/lung-function-gains-scarring-descreases-seen-study-ipf-therapy-env-101/', 'title': 'Lung function gains, scarring decreases seen in study of 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Atrasentan may reduce insulin...', 'thumbnail': 'https://serpapi.com/searches/6724a07515c740400600f8aa/images/ca0f769a0a7773d5f34cf1f3a80bd88ed42bb370383274579dc3ef5fa28e89f9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7896155714988708}",,,,,,,,,,['neutral'],neutral,1 NCT00098878,"{'position': 1, 'link': 'https://ovariancancernewstoday.com/2020/08/04/study-tests-used-to-predict-response-to-parp-inhibitors-yield-inconsistent-result/', 'title': 'Study: Tests Used to Predict Response to PARP Inhibitors Yield Inconsistent Result', 'source': 'Ovarian Cancer News Today', 'date': 'Aug 4, 2020', 'snippet': 'Tests used in clinical trials of ovarian cancer to determine if tumors lack \nthe ability to repair their DNA — a status termed “homologous...', 'thumbnail': 'https://serpapi.com/searches/6724a07bd771bd3d1c3e40a6/images/d6647d6bc25cde7c69f0cdca3b0fcf226f681ac0691f73a6d9fb5669df99dbc4.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.757084310054779}",,,,,,,,,,['neutral'],neutral,1 NCT02303678,"{'position': 1, 'link': 'https://www.researchgate.net/figure/a-A-brain-histopathologic-picture-shows-that-the-encephalomalacia-ECM-within-the-red_fig2_289367333', 'title': 'a A brain histopathologic picture shows that the encephalomalacia (ECM,...', 'source': 'ResearchGate', 'date': 'Apr 5, 2021', 'snippet': 'Pseudomonas aeruginosa exotoxin A-based immunotoxins (PE-ITs) are fusion \nproteins that harness targeting and toxin moieties. 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Learn \nmore about its uses, side effects, and clinical testing.', 'thumbnail': 'https://serpapi.com/searches/6724a0c98b84c4690f808b48/images/127cda1ee9fef3556f9b9f09347b08da61458b064146dee98c063882642fff36.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9291795492172241}",,,,,,,,,,['neutral'],neutral,1 NCT03472365,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-32570-z', 'title': 'Predicting response to immunotherapy in gastric cancer via multi-dimensional analyses of the tumour immune microenvironment', 'source': 'Nature', 'date': 'Aug 18, 2022', 'snippet': 'A single biomarker is not adequate to identify patients with gastric cancer \n(GC) who have the potential to benefit from anti-PD-1/PD-L1...', 'thumbnail': 'https://serpapi.com/searches/6724a0cb06f4f2e5cefaec56/images/a969764fceaf3f569815ec8661c2db56b50776ce170af8e61a636cf02920636f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6853904724121094}",,,,,,,,,,['neutral'],neutral,1 NCT01171859,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/jnc.15233', 'title': 'Targeting transthyretin - Mechanism-based treatment approaches and future perspectives in hereditary amyloidosis', 'source': 'Wiley Online Library', 'date': 'Nov 6, 2020', 'snippet': 'TTR stabilization and knockdown are approved therapies to mitigate the \notherwise lethal disease course. 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'sentiment_prob': 0.6689450144767761}",,,,,,,,,,['neutral'],neutral,1 NCT02669810,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-47079-8', 'title': 'Development of a potency assay for CD34+ cell-based therapy - Scientific Reports', 'source': 'Nature', 'date': 'Nov 11, 2023', 'snippet': 'We have previously shown that intracardiac delivery of autologous CD34+ \ncells after acute myocardial infarction (AMI) is safe and leads to...', 'thumbnail': 'https://serpapi.com/searches/6724a288fbde0d025ef89c19/images/8814ae75b719811c19e556ad3c4acaff17b1844b5a2e5bf620be2ce9dde5a399.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5865443348884583}","{'position': 2, 'link': 'https://www.europeanpharmaceuticalreview.com/article/184185/regenerative-potential-cell%E2%80%91based-therapies-for-heart-failure/', 'title': 'Regenerative potential: cell‑based therapies for heart failure', 'source': 'European Pharmaceutical Review', 'date': 'Jul 27, 2023', 'snippet': 'Dr Ibon Garitaonandia shares how CD34+ cell therapies are demonstrating \npromise in clinical studies as an alternative to heart transplants.', 'thumbnail': 'https://serpapi.com/searches/6724a288fbde0d025ef89c19/images/8814ae75b719811c136239f0471eb491d48075688b07b0a0d735403447b15dbd.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5993127226829529}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT04721223,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01589-z', 'title': 'Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials', 'source': 'Nature', 'date': 'Sep 6, 2023', 'snippet': 'In this review, we focus on the recent development of drug discovery \ntargeting “undruggable” proteins and their application in clinic.', 'thumbnail': 'https://serpapi.com/searches/6724a29c90b57c461dea5f81/images/b72ef227e8eb7d2d1dc06b630fed5cbba905856b0812173b47585572556dfbae.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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Today', 'date': 'Mar 2, 2020', 'snippet': ""Remsima, an approved biosimilar of Remicade for active Crohn's and \nulcerative colitis, was safe and effective given as a potential..."", 'thumbnail': 'https://serpapi.com/searches/6724a2b9cf32e043b585fc4f/images/b00b9e3d42c033a23000a07ebbf7a45a9e0f039340943050b7bc1fa803048ca2.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6795647144317627}",,,,,,,,,,['positive'],positive,1 NCT05017480,"{'position': 1, 'link': 'https://nationaleczema.org/blog/connect-1522/', 'title': 'Connect Biopharma Reports Detailed Positive Dataset from the Global Phase 2b Trial of CBP-201 in Adult Patients with Moderate-to-Severe Atopic Dermatitis', 'source': 'National Eczema Association', 'date': 'Feb 10, 2022', 'snippet': 'Connect Biopharma today reported detailed positive data from the global \nPhase 2b clinical trial of CBP-201 administered subcutaneously (SC)...', 'thumbnail': 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'Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape', 'source': 'The Lancet', 'date': 'Aug 8, 2022', 'snippet': 'A study to evaluate the safety and efficacy of mRNA-1345 vaccine targeting \nrespiratory syncytial virus (RSV) in adults ≥60 years of age.', 'thumbnail': 'https://serpapi.com/searches/6724a2e91315026fdb94b99b/images/9793bbf8cef5cbc52a3a2877ae525f7ad06c979957534c512ec0d464f9c28f3f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8734835982322693}",,,,,,,,,,['neutral'],neutral,1 NCT04896086,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-54876-2', 'title': 'Mosaic quadrivalent influenza vaccine single nanoparticle characterization | Scientific Reports', 'source': 'Nature', 'date': 'Feb 24, 2024', 'snippet': 'Recent work by our laboratory and others indicates that co-display of \nmultiple antigens on protein-based nanoparticles may be key to induce...', 'thumbnail': 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resubmits request for batoclimab approval in China', 'source': 'Myasthenia Gravis News', 'date': 'Jul 2, 2024', 'snippet': 'Harbour BioMed resubmitted an application to regulators in China, with \nadded long-term safety data, seeking approval of batoclimab for gMG.', 'thumbnail': 'https://serpapi.com/searches/6724a36a1fc7c565347dfd98/images/1a2eb80087f61bdc1b9c65f851c827f3ed62b32e71f8a3243d2f07ded7a9c985.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8841829299926758}","{'position': 2, 'link': 'https://myastheniagravisnews.com/news/mg-therapy-batoclimab-hits-phase-3-trial-main-secondary-goals/', 'title': 'MG therapy batoclimab hits Phase 3 trial main, secondary goals |...', 'source': 'Myasthenia Gravis News', 'date': 'Mar 7, 2023', 'snippet': 'Batoclimab eased the symptoms of generalized myasthenia gravis and their \nimpact on daily function in a Phase 3 clinical trial in China.', 'thumbnail': 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'source': 'Nature', 'date': 'Jan 29, 2024', 'snippet': 'Pre-clinical studies suggest AZD1775, a WEE1 kinase inhibitor, potentiates \nthe activity of various chemotherapeutic agents.', 'thumbnail': 'https://serpapi.com/searches/6724a55717b10ef88bd2d49b/images/c603b595868fe2c02ae058176a8274653012c4021d16aa76ab3f0fb355da3cec.png', 'sentiment': 'neutral', 'sentiment_prob': 0.86203533411026}",,,,,,,,,,['neutral'],neutral,1 NCT02089685,"{'position': 1, 'link': 'https://melanomanewstoday.com/2016/10/20/keytruda-pembrolizumab-plus-yervoy-ipilimumab-seen-as-safe-effective-for-advanced-melanoma-in-study/', 'title': 'Advanced Melanomas Seen to Respond to Keytruda-Yervoy Combo in Study', 'source': 'Melanoma News Today', 'date': 'Oct 20, 2016', 'snippet': 'Data from a Phase 1/2 study found a Keytruda-Yervoy combination to have \npotent anti-tumor activity and acceptable toxicity in advanced...', 'thumbnail': 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levels in RAP-ALS trial', 'source': 'ALS News Today', 'date': 'Nov 1, 2023', 'snippet': 'The RAP-ALS trial enrolled 63 participants who were randomly assigned to \nreceive one of two doses of rapamycin or a placebo for 18 weeks.', 'thumbnail': 'https://serpapi.com/searches/6724a5848e13c9b4d3ecae55/images/31fe5454f713a47c32a1c7d30968c177bc49c041dadea51a2975c0f6794dcf2a.png', 'sentiment': 'negative', 'sentiment_prob': 0.5977686047554016}",,,,,,,,,"['neutral', 'negative']",neutral,1 NCT01772472,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/reports/t-dm1-improves-os-vs-trastuzumab-breast-cancer-residual-disease/', 'title': 'T-DM1 Improves OS vs Trastuzumab in Breast Cancer Patients With Residual Disease', 'source': 'Cancer Therapy Advisor', 'date': 'Dec 12, 2023', 'snippet': 'Updated results from the KATHERINE trial suggest that ado-trastuzumab \nemtansine(T-DM1) can improve overall survival (OS) when compared to \ntrastuzumab.', 'thumbnail': 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invasive disease in KATHERINE', 'source': 'Nature', 'date': 'Sep 19, 2022', 'snippet': 'In this descriptive report we provide available outcome information in \nKATHERINE patients with HER2-negative status on re-testing of residual \ndisease after...', 'thumbnail': 'https://serpapi.com/searches/6724a5bafc40bf9c9759a6ec/images/e761e511104e4df7b98ae5373367f3696bc13f7e3144939068311d815f9feee8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8909833431243896}","{'position': 4, 'link': 'https://www.targetedonc.com/view/gupta-discusses-t-dm1-s-role-in-her2-breast-cancer-treatment', 'title': 'Gupta Discusses T-DM1’s Role in HER2+ Breast Cancer Treatment', 'source': 'Targeted Oncology', 'date': '1 week ago', 'snippet': 'Tanya Gupta, MD, medical oncologist in the Stanford University Department \nof Medicine, Division of Medical Oncology, discusses the use of...', 'thumbnail': 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Agents like T-DM1, T-DXd, and sacituzumab govitecan \ncontinue to change...', 'thumbnail': 'https://serpapi.com/searches/6724a5bafc40bf9c9759a6ec/images/e761e511104e4df7883cdb638ed7cd8a33a85e3eda7fce3c057de430a930d418.png', 'sentiment': 'positive', 'sentiment_prob': 0.5587568879127502}","{'position': 6, 'link': 'https://www.nature.com/articles/bjc2015426', 'title': 'Pathological complete response and prognosis after neoadjuvant chemotherapy for HER2 -positive breast cancers before and after trastuzumab era: results from a real-life cohort', 'source': 'Nature', 'date': 'Dec 10, 2015', 'snippet': 'Trastuzumab was introduced a decade ago and has improved outcomes for \nHER2-positive breast cancer. We investigated the factors predictive of...', 'thumbnail': 'https://serpapi.com/searches/6724a5bafc40bf9c9759a6ec/images/e761e511104e4df7a22aa4791be0834eb0ebdf477b86ca53817012188c3f39d2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5087625980377197}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'positive', 'neutral']",neutral,1 NCT01607957,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1414325', 'title': 'Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer', 'source': 'The New England Journal of Medicine', 'date': 'May 14, 2015', 'snippet': 'Early clinical trials conducted primarily in Japan have shown that TAS-102, \nan oral agent that combines trifluridine and tipiracil...', 'thumbnail': 'https://serpapi.com/searches/6724a5f1b4b72d4da19d6533/images/5dcfa2f3e82f3ed8694026204e23c00ac0abb988db4dd2e1d387b068ae29d4a7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9155271053314209}",,,,,,,,,,['neutral'],neutral,1 NCT04576988,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2213558', 'title': 'Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension', 'source': 'The New England Journal of Medicine', 'date': 'Mar 6, 2023', 'snippet': 'Sotatercept is a fusion protein that traps activins and growth \ndifferentiation factors involved in pulmonary arterial hypertension.', 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d16729b236c32fe5872abac9d648ca37ca4a9361d14c68a0bd610d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9086381196975708}","{'position': 2, 'link': 'https://www.biospace.com/drug-development/winrevair-sotatercept-is-now-authorized-for-use-in-canada-for-adults-with-pulmonary-arterial-hypertension', 'title': 'WINREVAIR® (sotatercept) is now authorized for use in Canada for Adults with Pulmonary Arterial Hypertension', 'source': 'BioSpace', 'date': 'Sep 4, 2024', 'snippet': 'KIRKLAND, QC, Sept. 4, 2024 /CNW/ - Merck (NYSE: MRK), known as MSD outside \nof the United States and Canada, announced that WINREVAIR®...', 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d16729ace9bc3678a79d598fa2141c07256d3af5172e8ded419153.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7694499492645264}","{'position': 3, 'link': 'https://www.renalandurologynews.com/news/winrevair-approved-for-pulmonary-arterial-hypertension/', 'title': 'Winrevair Approved for Pulmonary Arterial Hypertension', 'source': 'Renal and Urology News', 'date': 'Apr 5, 2024', 'snippet': 'The Food and Drug Administration (FDA) has approved Winrevair™ \n(sotatercept-csrk) for the treatment of adults with pulmonary arterial...', 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d16729527de7f64bd168b7ee4451e92a4249721b9b64677eb3b2f3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8045995235443115}","{'position': 4, 'link': 'https://pulmonaryhypertensionnews.com/news/winrevair-pah-treatment-adults-available-soon-us/', 'title': 'Winrevair, PAH treatment for adults, likely available soon in US', 'source': 'Pulmonary Hypertension News', 'date': 'Apr 10, 2024', 'snippet': 'The PAH injection therapy, recently approved in U.S., is expected to be \navailable via CVS and Accredo pharmacies by late April, Merck says.', 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d167290385e8409c28bc6167c49b13f73eb75d95abf048d7770f94.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7326827645301819}","{'position': 5, 'link': 'https://pulmonaryhypertensionnews.com/news/treatment-safety-efficacy-sotatercept-affected-antibodies/', 'title': 'Treatment safety, efficacy of sotatercept not affected by antibodies', 'source': 'Pulmonary Hypertension News', 'date': 'Dec 20, 2023', 'snippet': ""Antibodies that targeted sotatercept were not found to affect the therapy's \nsafety or effectiveness in an analysis of a clinical trial."", 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d16729a6e271458f00d23b55761d799f5db98cf8ab0e9d159b44c2.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8010830879211426}","{'position': 6, 'link': 'https://pulmonaryhypertensionnews.com/news/model-predicts-sotatercept-therapy-extend-survival-pah-patients/', 'title': 'Model predicts sotatercept will extend survival in PAH patients', 'source': 'Pulmonary Hypertension News', 'date': 'Nov 8, 2023', 'snippet': 'A prediction model estimated that add-on sotatercept will prolong survival \nby threefold for pulmonary arterial hypertension (PAH) patients.', 'thumbnail': 'https://serpapi.com/searches/6724a60008abe4633d04cf57/images/dba6759850d1672963babaa7002f3e353cb4c712fbdc2621ff955570c5741cf8.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5423300266265869}",,,,,"['neutral', 'neutral', 'neutral', 'neutral', 'neutral', 'neutral']",neutral,1 NCT03672604,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/nly01-fails-slow-motor-symptom-progression-phase-2-trial/', 'title': 'NLY01 fails to slow motor symptom progression in Phase 2 trial |...', 'source': ""Parkinson's News Today"", 'date': 'Mar 28, 2023', 'snippet': ""A Phase 2 clinical trial of Neuraly's NLY01 failed to show the experimental \ntherapy was superior to a placebo at significantly slowing motor..."", 'thumbnail': 'https://serpapi.com/searches/6724a608483e5b507c61e0fc/images/94cc9e97b86907edd3d0c75ca1bc453ac9b31da09264c7e47369ee5eb272ed16.png', 'sentiment': 'negative', 'sentiment_prob': 0.732501208782196}","{'position': 2, 'link': 'https://alzheimersnewstoday.com/news/fda-clears-neuraly-begin-phase-2b-clinical-trial-nly01-alzheimers-patients/', 'title': ""Neuraly Cleared by FDA for Phase 2 Trial of NLY01 in Alzheimer's Patients"", 'source': ""Alzheimer's News Today"", 'date': 'Nov 16, 2020', 'snippet': 'The U.S. Food and Drug Administration has given clearance for a Phase 2B \nclinical trial to evaluate the safety, tolerability, and efficacy...', 'thumbnail': 'https://serpapi.com/searches/6724a608483e5b507c61e0fc/images/94cc9e97b86907ed8889f455dd78ed060c66395f42ef2107da2622d9482fbf00.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8326922059059143}",,,,,,,,,"['negative', 'neutral']",negative,0 NCT02546167,"{'position': 1, 'link': 'https://www.nature.com/articles/s41408-021-00469-5', 'title': 'CAR T-cell therapy in multiple myeloma: more room for improvement - Blood Cancer Journal', 'source': 'Nature', 'date': 'Apr 29, 2021', 'snippet': 'The emergence of various novel therapies over the last decade has changed \nthe therapeutic landscape for multiple myeloma. While the clinical...', 'thumbnail': 'https://serpapi.com/searches/6724a62ea869211c6ffe4ec4/images/5a170cc807c313df5f6638f1f41b6412b0c8b4e5332c22b8f9a0a380180439ae.png', 'sentiment': 'positive', 'sentiment_prob': 0.5632189512252808}",,,,,,,,,,['positive'],positive,1 NCT03792633,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1111/ejh.14132', 'title': 'Determinants of outcomes and advances in CD19-directed chimeric antigen receptor therapy for B-cell acute lymphoblastic leukemia', 'source': 'Wiley Online Library', 'date': 'Dec 17, 2023', 'snippet': 'European Journal of Haematology is an international haematology journal for \nbasic & clinical research, covering all diseases of the blood,...', 'thumbnail': 'https://serpapi.com/searches/6724a66a0a545a252611fc33/images/9cf10dd09871a36e7444839c16e2c89da917da9e2878e5ebee239dd192cc02d1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9273737072944641}",,,,,,,,,,['neutral'],neutral,1 NCT05607680,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/easd-2024-innovent-shows-off-mazdutides-efficacy-in-diabetes-and-obesity/', 'title': 'EASD 2024: Innovent shows off mazdutide’s efficacy in diabetes and obesity', 'source': 'Clinical Trials Arena', 'date': '1 month ago', 'snippet': ""The data from two Phase III trials demonstrated GLP-1/glucagon agonist's \nefficacy in reducing blood glucose and weight."", 'thumbnail': 'https://serpapi.com/searches/6724a68498d8dedb6c797900/images/83be1f6a5c74044a5a138734913c2d7a0f1a369960436eb3fdf78bff17bf4e52.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7004231810569763}","{'position': 2, 'link': 'https://www.prnewswire.com/news-releases/innovent-announces-mazdutide-demonstrates-80-2-reduction-in-liver-fat-content-in-exploratory-analysis-of-phase-3-weight-management-glory-1-study-at-ada-2024--302180984.html', 'title': 'Innovent Announces Mazdutide Demonstrates 80.2% Reduction in Liver Fat Content in Exploratory Analysis of Phase 3 Weight Management GLORY-1 Study at ADA 2024', 'source': 'PR Newswire', 'date': 'Jun 24, 2024', 'snippet': 'The results of the GLORY-1 study further support that mazdutide may promote \nliver fat metabolism through the stimulation of GCGR and significantly \nreduce liver...', 'thumbnail': 'https://serpapi.com/searches/6724a68498d8dedb6c797900/images/83be1f6a5c74044aba4bda7bf8149e3149565084edcd98d7cd53e586386bb613.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5326186418533325}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT03006705,"{'position': 1, 'link': 'https://www.cancertherapyadvisor.com/reports/adjuvant-nivolumab-gastric-gej-cancer-no-benefit/', 'title': 'No Benefit Seen With Adjuvant Nivolumab in Gastric/GEJ Cancer', 'source': 'Cancer Therapy Advisor', 'date': 'Jun 3, 2023', 'snippet': 'Adding nivolumab to adjuvant chemotherapy did not improve relapse-free \nsurvival in a phase 3 trial of patients with gastric/GEJ cancer.', 'thumbnail': 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'https://www.ajmc.com/view/tolebrutinib-96-week-mri-results-promising-for-the-investigational-btk-inhibitor', 'title': 'Tolebrutinib 96-Week MRI Results Promising for the Investigational BTK Inhibitor', 'source': 'AJMC', 'date': 'Apr 25, 2023', 'snippet': 'Two-year data on MRI, efficacy, and safety findings from the long-term \nsafety extension study of the investigational Bruton tyrosine kinase...', 'thumbnail': 'https://serpapi.com/searches/6724a6ad0a545a252611fc49/images/1f57434d9ddcee883d61400b9848ac46c416c9699168e1dc34f41e113d2e2752.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7719200253486633}","{'position': 3, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2020/12/14/sanofi-enrolling-for-2-gemini-clinical-trials-testing-experimental-tolebrutinib-vs-aubagio-for-relapsing-ms/', 'title': 'Sanofi Enrolling for 2 GEMINI Trials Testing Tolebrutinib vs. Aubagio for Relapsing MS', 'source': 'Multiple Sclerosis News Today', 'date': 'Dec 14, 2020', 'snippet': ""Sanofi Genzyme's global clinical trials GEMINI 1 and 2, comparing \ntolebrutinib versus Aubagio, are enrolling 1800 relapsing MS patients."", 'thumbnail': 'https://serpapi.com/searches/6724a6ad0a545a252611fc49/images/1f57434d9ddcee88c3a7ae6631b0ea6ecf50ab5d48309c166e7ee1fb317f0e72.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9530969858169556}","{'position': 4, 'link': 'https://multiplesclerosisnewstoday.com/news-posts/2023/10/16/ectrims-2023-tolebrutinib-prevents-relapses-lesions-3-years/', 'title': 'ECTRIMS 2023: Tolebrutinib found to show benefits for up to 3 years', 'source': 'Multiple Sclerosis News Today', 'date': 'Oct 16, 2023', 'snippet': 'Three years of treatment with tolebrutinib was linked to low relapses rates \nand few new brain lesions among relapsing MS patients,...', 'thumbnail': 'https://serpapi.com/searches/6724a6ad0a545a252611fc49/images/1f57434d9ddcee88d39e6c872fcc47bb3388f4fba0432af67710b0fb5e10c6f5.png', 'sentiment': 'positive', 'sentiment_prob': 0.7722958922386169}",,,,,,,"['neutral', 'neutral', 'neutral', 'positive']",neutral,1 NCT00473382,"{'position': 1, 'link': 'https://www.nature.com/articles/s41746-019-0172-3', 'title': 'Deep learning algorithm predicts diabetic retinopathy progression in individual patients | npj Digital Medicine', 'source': 'Nature', 'date': 'Sep 20, 2019', 'snippet': 'We describe an algorithm to predict DR progression by means of deep \nlearning (DL), using as input color fundus photographs (CFPs) acquired at a \nsingle visit...', 'thumbnail': 'https://serpapi.com/searches/6724b353f3cbfaa2d1619239/images/1d7a77ff4041f1ce57241338a1c87d3f15f99f5138d99843de7e3bccb2448274.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9201077818870544}",,,,,,,,,,['neutral'],neutral,1 NCT03239340,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-35961-y', 'title': 'Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer', 'source': 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agonist of kappa \nopioid receptors that are considered to be important in modulating pruritus \nin...', 'thumbnail': 'https://serpapi.com/searches/6724b31cadc33b8213216a3e/images/cb28385c312f2e9e39d1471fb82df3f930d25e15c5fcdd68fc07279e5cd2d73c.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9009538888931274}","{'position': 2, 'link': 'https://www.empr.com/home/news/korsuva-approved-for-chronic-kidney-disease-associated-pruritus/', 'title': 'Korsuva Approved for Chronic Kidney Disease-Associated Pruritus', 'source': 'Medical Professionals Reference', 'date': 'Aug 24, 2021', 'snippet': 'The Food and Drug Administration has approved Korsuva™ (difelikefalin) \ninjection for the treatment of moderate to severe pruritus associated...', 'thumbnail': 'https://serpapi.com/searches/6724b31cadc33b8213216a3e/images/cb28385c312f2e9e854e1f1b80b190bcad167207dd52a173c9fddf664bb87ef8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.87298184633255}","{'position': 3, 'link': 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appropriate mouse models is likely one of the reasons of a \nlimited translational success rate of therapeutic vaccines against...', 'thumbnail': 'https://serpapi.com/searches/6724a72230dfc1bbc8a085b8/images/8a7ceede7dbe49c6639b40f02f95dfdb666dc1da1957b7900ec2ddf822b33de3.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6804020404815674}",,,,,,,,,,['negative'],negative,0 NCT05514548,"{'position': 1, 'link': 'https://www.clinicaltrialsarena.com/news/novo-nordisk-weight-loss-drug-questions-remain/', 'title': 'Questions over Novo Nordisk $1bn weight loss drug after Phase IIa trial', 'source': 'Clinical Trials Arena', 'date': '1 month ago', 'snippet': 'Novo Nordisk acquired monlunabant in a $1bn deal in 2023, but the Phase IIa \ntrial raises questions over the efficacy and safety ratio.', 'thumbnail': 'https://serpapi.com/searches/6724a731310300dc7f4f1315/images/b370adf81c1da88be13ae2e8043587fdfe270dc2c5ce413cf278e791d9692375.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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'May 16, 2024', 'snippet': ""Roche's GLP-1/GIP receptor agonist, which it gained in the Carmot \nacquisition, showed 18.8% weight loss in a Phase Ib trial."", 'thumbnail': 'https://serpapi.com/searches/6724a77f7f371998d77793b1/images/975bd46c111f6be39378632cca6cf1b12873ccdcfb198628c96cff9a4b99131c.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6271388530731201}",,,,,,,,,,['positive'],positive,1 NCT05006352,"{'position': 1, 'link': 'https://alsnewstoday.com/news/dnl343-well-tolerated-interim-als-clinical-trial-data/', 'title': 'DNL343 Well-tolerated, Interim ALS Clinical Trial Data Show', 'source': 'ALS News Today', 'date': 'Dec 15, 2022', 'snippet': 'DNL343 can enter the brain and reduce the cellular stress response that \ncontributes to disease progression, ALS clinical trial analysis...', 'thumbnail': 'https://serpapi.com/searches/6724a77fb57db83e86a1eaa6/images/1f7b08faf9ab3c60ddba8719da16b1bd1b12e491114d2c4f30417203f667b699.png', 'sentiment': 'positive', 'sentiment_prob': 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""The World Health Organization approved the name ensifentrine for Verona \nPharma's investigational bronchodilator and anti-inflammatory agent,..."", 'thumbnail': 'https://serpapi.com/searches/6724a7c948c4292d95eb3e28/images/75be26e02c2b2df42fcb4488aa57399faee668abfa0ed47ea4d37b79272debd2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8575579524040222}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT01346358,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Dose-Cohort-Assignment-QW-weekly-Q2W-every-2weeks_fig1_349542499', 'title': 'Dose Cohort Assignment. QW: weekly; Q2W: every 2 weeks', 'source': 'ResearchGate', 'date': 'Jun 13, 2021', 'snippet': 'This phase 1 study determined the safety, tolerability, \npharmacokinetics-pharmacodynamics, immunogenicity, and efficacy of the \nanti–CSF-1R antibody LY3.', 'thumbnail': 'https://serpapi.com/searches/6724a8033c9575fb6f910a49/images/2af96679d363288d2a311111ecad6fa573fdef6d31222c4715710d9894468454.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8917114734649658}",,,,,,,,,,['neutral'],neutral,1 NCT01447017,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-023-41581-9', 'title': 'Novel cationic cryptides in Penaeus vannamei demonstrate antimicrobial and anti-cancer activities', 'source': 'Nature', 'date': 'Sep 6, 2023', 'snippet': 'In the current study, we employed an in silico approach to identify novel \ncationic cryptides with potential antimicrobial and anti-cancer activities.', 'thumbnail': 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'title': 'Immunogenicity and safety of AZD2816, a beta (B.1.351) variant COVID-19 vaccine, and AZD1222 (ChAdOx1 nCoV-19) as third-dose boosters for previously vaccinated adults: a multicentre, randomised, partly double-blinded, phase 2/3 non-inferiority immuno', 'source': 'The Lancet', 'date': 'Sep 29, 2023', 'snippet': 'A multicentre, randomised, partly double-blinded, phase 2/3 non-inferiority \nimmunobridging study in the UK and Poland', 'thumbnail': 'https://serpapi.com/searches/6724a85af79a0107d03b7138/images/806d734610e2f155cc32d722ebc6015b0bfd0efbd4f9e156ff9b37ea21ea1509.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8618715405464172}",,,,,,,,,,['neutral'],neutral,1 NCT04398433,"{'position': 1, 'link': 'https://www.empr.com/home/news/ino-3107-recurrent-respiratory-papillomatosis-breakthrough-status/', 'title': 'DNA Therapy Gets Breakthrough Status for Recurrent Respiratory Papillomatosis', 'source': 'Medical Professionals Reference', 'date': 'Sep 7, 2023', 'snippet': 'The Food and Drug Administration (FDA) has granted Breakthrough Therapy \ndesignation to INO-3107 for the treatment of recurrent respiratory \npapillomatosis.', 'thumbnail': 'https://serpapi.com/searches/6724a8681397ba76bd3ea7f2/images/98e68753d95aba31e9416952885eb47610e5168087e3fe855900d9e28df7b80b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6652581095695496}",,,,,,,,,,['neutral'],neutral,1 NCT04163016,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/Cimzia', 'title': 'Certolizumab Pegol (Cimzia®)', 'source': 'UCB', 'date': 'Oct 12, 2018', 'snippet': 'Axial Spondyloarthritis, Certolizumab Pegol in Subjects With Active Axial \nSpondyloarthritis, Phase 3, AKS001 Completed, NCT01087762 · 2009-011719-19 \n· LINK', 'thumbnail': 'https://serpapi.com/searches/6724a8729936886f9ed7a89c/images/350149cb62698a4ef1f6f8636d3b1645c397203b77250cea659898498b351ea8.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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by 31%', 'source': 'Clinical Trials Arena', 'date': '1 month ago', 'snippet': 'After missing primary endpoints in relapsing forms of MS, tolebrutinib has \nproved its efficacy in secondary progressive MS patients.', 'thumbnail': 'https://serpapi.com/searches/6724a8c18d147358ee7a5fd5/images/2ffc77b3f9a8ea054bbcd3ac15422ce140b331334c94ad8ebb396f3bb8643afc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.4900601804256439}",,,,,,,,,,['neutral'],neutral,1 NCT01591447,"{'position': 1, 'link': 'https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6206a3.htm', 'title': 'CDC Grand Rounds: The Growing Threat of Multidrug-Resistant Gonorrhea', 'source': 'Centers for Disease Control and Prevention (.gov)', 'date': 'Feb 15, 2013', 'snippet': 'Although gonorrhea has afflicted humans for centuries, and the causative \nbacterium, Neisseria gonorrhoeae, was identified more than a...', 'thumbnail': 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that support Ovid Therapeutics' \ndecision to stop clinical testing of OV101 for Angelman..."", 'thumbnail': 'https://serpapi.com/searches/6724a99b358539552e83d3fc/images/e6aa35a846864260b0ebb9f65e58ca30a520452c5470ff2f6fe88eb9b6d1a50a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8800973892211914}",,,,,,,,,,['neutral'],neutral,1 NCT04383574,"{'position': 1, 'link': 'https://www.researchgate.net/figure/Examples-of-marketed-Vero-cell-based-vaccines_tbl1_343465585', 'title': 'Examples of marketed Vero cell-based vaccines.', 'source': 'ResearchGate', 'date': 'Sep 21, 2020', 'snippet': 'The Vero cell line is considered the most used continuous cell line for the \nproduction of viral vectors and vaccines.', 'thumbnail': 'https://serpapi.com/searches/6724b2b7b4fe87c770de3eb3/images/f9e8e5db90b9aa7f58319a25a8472fb007840084f22b9ddbf313c0672405c77f.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8455920219421387}",,,,,,,,,,['neutral'],neutral,1 NCT00412984,"{'position': 1, 'link': 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Receives BARDA Project NextGen Award Valued at up to $338 Million to Advance Intranasal NDV-based COVID-19 Booster Vaccine into Phase 2b Clinical Efficacy Testing', 'source': 'Mount Sinai', 'date': 'Oct 17, 2023', 'snippet': 'CastleVax, a clinical stage vaccine platform company, has received a \nProject NexGen award valued at up to $338 million from the Biomedical...', 'thumbnail': 'https://serpapi.com/searches/6724a9fd0377569610781db2/images/f361b4d34203c9c2a982dc1b0c3f94cd45491edc311f0da388bdfc82319bdeeb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7130514979362488}","{'position': 2, 'link': 'https://www.businesswire.com/news/home/20240730713002/en/CastleVax-Inc.-Receives-34-Million-from-BARDA-to-Continue-Advancing-Intranasal-NDV-based-COVID-19-Vaccine-into-Phase-2b-Clinical-Efficacy-Testing', 'title': 'CastleVax Inc. Receives $34 Million from BARDA to Continue Advancing Intranasal NDV-based COVID-19 Vaccine into Phase 2b Clinical Efficacy Testing', 'source': 'Business Wire', 'date': 'Jul 30, 2024', 'snippet': 'CastleVax, a clinical stage mucosal vaccine platform company, has received \nan additional Project NextGen award valued at approximately $34...', 'thumbnail': 'https://serpapi.com/searches/6724a9fd0377569610781db2/images/f361b4d34203c9c2d5fd1e9b9ab908af3fe680b2d34c4ea8696096e040f9d2f5.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6780118346214294}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03969212,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/10.1111/irv.13302', 'title': 'Comparative Effectiveness of Baloxavir Marboxil and Oseltamivir Treatment in Reducing Household Transmission of Influenza: A Post Hoc Analysis of the BLOCKSTONE Trial', 'source': 'Wiley Online Library', 'date': 'May 6, 2024', 'snippet': 'Background The transmission of influenza virus in households, especially by \nchildren, is a major route of infection. Prior studies suggest...', 'thumbnail': 'https://serpapi.com/searches/6724aa0e6273fb687d1a9e47/images/a7697010f95a81a80d85eec73399938dd0ecae485d4b1f61e451c5915e533d00.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7998299598693848}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1915341', 'title': 'Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts', 'source': 'The New England Journal of Medicine', 'date': 'Jul 8, 2020', 'snippet': 'Baloxavir marboxil (baloxavir) is a polymerase acidic protein (PA) \nendonuclease inhibitor with clinical efficacy in the treatment of...', 'thumbnail': 'https://serpapi.com/searches/6724aa0e6273fb687d1a9e47/images/a7697010f95a81a8bf94423b06c3e58120e6ea89fec26225555074433efb3a63.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8460713624954224}","{'position': 3, 'link': 'https://www.koreabiomed.com/news/articleView.html?idxno=20241', 'title': ""Influenza drug 'Xofluza' expands indication to over 1 year old 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Janjigian, MD, discusses results from the primary \nprogression-free survival and interim overall survival analyses of the \nphase 3...', 'thumbnail': 'https://serpapi.com/searches/6724aa52d9c3e6cd2651b633/images/72011a88512b16041fcb1fda253a400f55b41c396fb2f9be66e3e81777cdd691.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9270865321159363}",,,,,,,,,,['neutral'],neutral,1 NCT01668784,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1510665', 'title': 'Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma', 'source': 'The New England Journal of Medicine', 'date': 'Nov 6, 2016', 'snippet': 'Nivolumab, a programmed death 1 (PD-1) checkpoint inhibitor, was associated \nwith encouraging overall survival in uncontrolled studies involving \npreviously...', 'thumbnail': 'https://serpapi.com/searches/6724aa60765857d753f25859/images/6ae9f3b284cb4177db0b65858c94a6352c47383acf4a7138c74a59188b80db03.png', 'sentiment': 'neutral', 'sentiment_prob': 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installement of Clinical Quandaries, Abigail Mateos-Soria, MD, and \ncolleagues present a case of an 38-year-old woman who has a...', 'thumbnail': 'https://serpapi.com/searches/6724aa9a717bff511bd207e7/images/2feb654599fa537407fb391c37d45c169fc9fa836b9f9092da5391f54a8d3696.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9248615503311157}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01455701,"{'position': 1, 'link': 'https://juvenilearthritisnews.com/2019/09/10/tocilizumab-is-safe-and-effective-to-treat-sjia-infants-younger-than-2/', 'title': 'Tocilizumab Safe, Effective to Treat Systemic JIA Infants 2 and Younger', 'source': 'Juvenile Arthritis News', 'date': 'Sep 10, 2019', 'snippet': 'Data from a Phase 1 clinical trial demonstrated that treatment with \ntocilizumab is a safe and effective treatment for sJIA in infants...', 'thumbnail': 'https://serpapi.com/searches/6724aab29109860c4561e89b/images/4d45e0b33bec893bd0e96dd5e387327c66888c02664aea9241fa6982c670a140.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5793243646621704}",,,,,,,,,,['positive'],positive,1 NCT00091949,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1506930', 'title': 'Pioglitazone after Ischemic Stroke or Transient Ischemic Attack', 'source': 'The New England Journal of Medicine', 'date': 'Feb 17, 2016', 'snippet': 'Pioglitazone would reduce the rates of stroke and myocardial infarction \nafter ischemic stroke or TIA in patients without diabetes who have insulin \nresistance.', 'thumbnail': 'https://serpapi.com/searches/6724aabdf6aa53974ffe804a/images/3ebbacc17a70874092bce16c4a0f2dc611efd770100858e0ebfc662280dc9864.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7776960730552673}",,,,,,,,,,['neutral'],neutral,1 NCT03877510,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/sustained-parkinsons-symptom-control-seen-with-ipx203-rise-pd-extension/', 'title': ""Sustained Parkinson's symptom control seen with IPX203 in RISE-PD extension"", 'source': ""Parkinson's News Today"", 'date': 'Jan 3, 2024', 'snippet': 'The final published results of the extension study, which included 419 \nparticipants from RISE-PD, indicate IPX203 remained safe and...', 'thumbnail': 'https://serpapi.com/searches/6724aac6ea57e998e6b6d599/images/57a6b14659ef5adb159196a17173aebbbca7f62b9dc09f0229989b19bda9f837.png', 'sentiment': 'neutral', 'sentiment_prob': 0.826775312423706}",,,,,,,,,,['neutral'],neutral,1 NCT03873116,"{'position': 1, 'link': 'https://angioedemanews.com/news/hae-attacks-fall-long-term-orladeyo-use-phase-3-trial-japan/', 'title': 'HAE attacks in adults fall with long-term use of Orladeyo: Phase 3 trial', 'source': 'Angioedema News', 'date': 'Mar 25, 2024', 'snippet': 'Swelling attacks safely declined and life quality rose among adults in \nJapan treated with Orladeyo daily in a roughly 2-year clinical trial.', 'thumbnail': 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'https://www.nejm.org/doi/abs/10.1056/NEJMoa2209856', 'title': 'A Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis', 'source': 'The New England Journal of Medicine', 'date': 'Apr 12, 2024', 'snippet': 'Peresolimab is a humanized IgG1 monoclonal antibody designed to stimulate \nthe endogenous programmed cell death protein 1 (PD-1) inhibitory pathway.', 'thumbnail': 'https://serpapi.com/searches/6724aad0a5aae9a127b6a712/images/bc1d704b3ba3aaa8a0375ad979ae3a6268f5ea335759d50bfed51e240f9bbd8d.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8992647528648376}","{'position': 2, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2209856', 'title': 'A Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis', 'source': 'The New England Journal of Medicine', 'date': 'May 17, 2023', 'snippet': 'Peresolimab is a humanized IgG1 monoclonal antibody designed to stimulate \nthe endogenous programmed cell death protein 1 (PD-1) inhibitory...', 'thumbnail': 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Study evaluated a novel approach to treating \npatients with...', 'thumbnail': 'https://serpapi.com/searches/6724aad0a5aae9a127b6a712/images/bc1d704b3ba3aaa819490f7de8abb8c2d8ca135a5c7beadcd97f92240dd63cc7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6089026927947998}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT02113982,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1815105', 'title': 'Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm', 'source': 'The New England Journal of Medicine', 'date': 'Apr 24, 2019', 'snippet': 'Blastic plasmacytoid dendritic-cell neoplasm (BPDCN) is an aggressive \nhematologic cancer that is caused by transformed plasmacytoid...', 'thumbnail': 'https://serpapi.com/searches/6724aad1e6862b708a063a5c/images/a933e08089b84d3777d8ad79837bfab7aedb6a2c4506d84752d20150bad6cbb5.png', 'sentiment': 'negative', 'sentiment_prob': 0.6274949908256531}","{'position': 2, 'link': 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patients with \nschizophrenia, with efficacy similar to AOM 400.', 'thumbnail': 'https://serpapi.com/searches/6724aae41fc7c5650202ed4f/images/509720ca3449900591984861a32eee5cb6f4d97d11d463a427b96f1497a2cfad.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5956546664237976}",,,,,,,,,,['positive'],positive,1 NCT03085095,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2004325', 'title': 'Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer', 'source': 'The New England Journal of Medicine', 'date': 'May 29, 2020', 'snippet': 'Injectable luteinizing hormone–releasing hormone agonists (e.g., \nleuprolide) are the standard agents for achieving androgen deprivation \nfor...', 'thumbnail': 'https://serpapi.com/searches/6724aba3213c874a9e41e8a8/images/8526a9359f8c95ee9405fcaf5d3332a0b356dd26aa496e7a37da0960387005d7.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7869049310684204}",,,,,,,,,,['neutral'],neutral,1 NCT04440592,"{'position': 1, 'link': 'https://sclerodermanews.com/news/mt-7117-reduces-symptoms-scleroderma-mouse-model/', 'title': 'MT-7117 Reduces Symptoms of Scleroderma in Mouse Model |...', 'source': 'Scleroderma News', 'date': 'Sep 20, 2022', 'snippet': 'Treatment with the experimental therapy reduced lung inflammation, skin \nfibrosis, and blood vessel impairment in a scleroderma mouse model.', 'thumbnail': 'https://serpapi.com/searches/6724b20a360f4ebaf6f9cb71/images/f57b814c2764c74ac20fb1c74464ae3cac893cfb01b671ef4192a6abfc505b68.png', 'sentiment': 'neutral', 'sentiment_prob': 0.652198314666748}",,,,,,,,,,['neutral'],neutral,1 NCT03239392,"{'position': 1, 'link': 'https://www.cancernetwork.com/view/phase-3-trial-of-bnz-1-to-be-initiated-for-treatment-of-relapsed-refractory-ctcl', 'title': 'Phase 3 Trial of BNZ-1 To Be Initiated for Treatment of Relapsed/Refractory CTCL', 'source': 'Cancer Network', 'date': 'Jan 27, 2021', 'snippet': 'Bioniz Therapeutics announced it intends to launch a phase 3 clinical trial \nof the multi-cytokine inhibitor, BNZ-1, for the treatment of patients with \nrelapsed...', 'thumbnail': 'https://serpapi.com/searches/6724aafdcc4879b17e4d2d99/images/952f7f61cf064945e2ff52308212dcb37b8b4e5c198ed6fd4aeac899ed27ef58.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9129712581634521}",,,,,,,,,,['neutral'],neutral,1 NCT02491684,"{'position': 1, 'link': 'https://copdnewstoday.com/news/copd-patients-synairgen-sng001-flu-colds-phase-2-trial/', 'title': 'COPD Patients Get Synairgen’s SNG001 for Flu, Colds in Phase 2 Trial', 'source': 'COPD News Today', 'date': 'Oct 30, 2018', 'snippet': ""With SNG001, researchers hope to boost the body's antiviral system to fight \nrespiratory infections that tend to worsen COPD symptoms."", 'thumbnail': 'https://serpapi.com/searches/6724ab0e861b9da48b37be05/images/c5741db7cddc24c45c216764163116852a3389867f26698cc44d6e78d371552a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8367211222648621}",,,,,,,,,,['neutral'],neutral,1 NCT02612779,"{'position': 1, 'link': 'https://myelomaresearchnews.com/news/safety-concerns-prompt-fda-to-put-a-hold-on-opdivo-combination-trials-for-myeloma/', 'title': '3 Myeloma Trials of Opdivo Put on Hold Due to Safety Concerns Over Other Therapies', 'source': 'Myeloma Research News', 'date': 'Sep 8, 2017', 'snippet': 'The US Food and Drug Administration has ordered Bristol-Myers Squibb to put \na hold on three clinical trials evaluating Opdivo (nivolumab) in \ncombination with...', 'thumbnail': 'https://serpapi.com/searches/6724ab2bbcd6526351ce4fa4/images/6e05f69d544e808abcd7330355fc2db6cb8ffedce668653f47ebc24556187f20.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7855069041252136}",,,,,,,,,,['neutral'],neutral,1 NCT00933530,"{'position': 1, 'link': 'https://www.nature.com/articles/s41598-024-55923-8', 'title': 'Emerging roles of SIRT1 activator, SRT2104, in disease treatment', 'source': 'Nature', 'date': 'Mar 6, 2024', 'snippet': 'Silent information regulator 1 (SIRT1) is a NAD+-dependent class III \ndeacetylase that plays important roles in the pathogenesis of numerous...', 'thumbnail': 'https://serpapi.com/searches/6724ab4e17a2e2dbc6752d5a/images/b891353359872dc324d7d1c7bf263594a1d72e0ae0a09ec4ac79bab5967127fb.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8164551258087158}",,,,,,,,,,['neutral'],neutral,1 NCT04551547,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-34280-y', 'title': 'Safety and immunogenicity following a homologous booster dose of CoronaVac in children and adolescents', 'source': 'Nature', 'date': 'Nov 14, 2022', 'snippet': 'Data on safety and immunity elicited by a third booster dose of inactivated \nCOVID-19 vaccine in children and adolescents are scarce.', 'thumbnail': 'https://serpapi.com/searches/6724ab528a7c09b49ca09b46/images/b0def5c06bc1930c46ecb3e7631cf62e0456c2d9f9ef68669f729e4249891914.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8404264450073242}",,,,,,,,,,['neutral'],neutral,1 NCT02066181,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1805052', 'title': 'Sorafenib for Advanced and Refractory Desmoid Tumors', 'source': 'The New England Journal of Medicine', 'date': 'Dec 19, 2018', 'snippet': 'In this double-blind, phase 3 trial, we randomly assigned 87 patients with \nprogressive, symptomatic, or recurrent desmoid tumors to receive...', 'thumbnail': 'https://serpapi.com/searches/6724ab618b84c4694456d640/images/7b8f08099a380dbde87980e2b2570b89c39669afda2bb750291a18fcd12cda7e.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9053760766983032}",,,,,,,,,,['neutral'],neutral,1 NCT03112603,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2033122', 'title': 'Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease', 'source': 'The New England Journal of Medicine', 'date': 'Jul 14, 2021', 'snippet': 'Chronic graft-versus-host disease (GVHD), a major complication of \nallogeneic stem-cell transplantation, becomes glucocorticoid-refractory \nor...', 'thumbnail': 'https://serpapi.com/searches/6724ab8bb7d31d18676f5a97/images/b6005957a784c4c6ce469335a0a8ca9619eed8fdce2f01fa41eb1739e9f7c1e8.png', 'sentiment': 'negative', 'sentiment_prob': 0.663324773311615}",,,,,,,,,,['negative'],negative,0 NCT02668653,"{'position': 1, 'link': 'https://ascopost.com/news/july-2023/fda-approves-quizartinib-for-newly-diagnosed-flt3-itd-positive-acute-myeloid-leukemia/', 'title': 'FDA Approves Quizartinib for Newly Diagnosed FLT3 -ITD–Positive Acute Myeloid Leukemia', 'source': 'The ASCO Post', 'date': 'Jul 21, 2023', 'snippet': 'The US Food and Drug Administration (FDA) approved quizartinib (Vanflyta) \nwith standard cytarabine and anthracycline induction and cytarabine \nconsolidation.', 'thumbnail': 'https://serpapi.com/searches/6724abdb3ad34d26809da1f4/images/9c7dae9b57e710e01b55e6d28977c570decadb66deb456a4d06aa8cad03dfa99.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7984702587127686}","{'position': 2, 'link': 'https://www.cancernetwork.com/view/continued-quizartinib-may-show-benefit-in-select-flt3-itd-aml-population', 'title': 'Continued Quizartinib May Show Benefit in Select FLT3-ITD+ AML Population', 'source': 'Cancer Network', 'date': 'Jun 17, 2024', 'snippet': 'Additional analyses of patient-reported outcomes and MRD status in the \nQuANTUM-First trial are also ongoing, says Harry P. Erba, MD, PhD.', 'thumbnail': 'https://serpapi.com/searches/6724abdb3ad34d26809da1f4/images/9c7dae9b57e710e054a226adb793a512242938357db2b13a4cc18eeea49651dc.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8261187672615051}","{'position': 3, 'link': 'https://www.cancerhealth.com/blog/fda-approves-vanflyta-newly-diagnosed-acute-myeloid-leukemia', 'title': 'FDA Approves Vanflyta for Newly Diagnosed Acute Myeloid Leukemia', 'source': 'Cancer Health', 'date': 'Jul 21, 2023', 'snippet': 'Trial showed that treatment with quizartinib led to a significant \nimprovement in overall survival.', 'thumbnail': 'https://serpapi.com/searches/6724abdb3ad34d26809da1f4/images/9c7dae9b57e710e069db637f7b3679b86e7c5e8915ac0e483bd5d3991c65e70a.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7023189067840576}",,,,,,,,"['neutral', 'neutral', 'positive']",neutral,1 NCT01721044,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1507247', 'title': 'Baricitinib in Patients with Refractory Rheumatoid Arthritis', 'source': 'The New England Journal of Medicine', 'date': 'Mar 31, 2016', 'snippet': 'In phase 2 studies, baricitinib, an oral Janus kinase 1 and 2 inhibitor, \nreduced disease activity in patients with rheumatoid arthritis who...', 'thumbnail': 'https://serpapi.com/searches/6724ac0617b10e2469e2ca1b/images/14fc814316688715dd21f35e8c3b78d6a41aed6451210a737280545cab4eaa7b.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8679934144020081}","{'position': 2, 'link': 'https://rheumatoidarthritisnews.com/baricitinib-olumiant-for-rheumatoid-arthritis/', 'title': 'Baricitinib (Olumiant) for Rheumatoid Arthritis', 'source': 'Rheumatoid Arthritis News', 'date': 'Apr 24, 2017', 'snippet': 'Read about Baricitinib (Olumiant), which inhibits the inflammation \nassociated with rheumatoid arthritis, easing the joint pain that stems from \nthe disease.', 'thumbnail': 'https://serpapi.com/searches/6724ac0617b10e2469e2ca1b/images/14fc8143166887159351828a3e7428a298892aac3e66708de9f22e2ac590ea21.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.7946578860282898}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT03738215,"{'position': 1, 'link': 'https://www.empr.com/home/news/drugs-in-the-pipeline/vraylar-approved-as-adjunctive-therapy-for-major-depressive-disorder/', 'title': 'Vraylar Approved as Adjunctive Therapy for Major Depressive Disorder', 'source': 'Medical Professionals Reference', 'date': 'Dec 19, 2022', 'snippet': 'The Food and Drug Administration (FDA) has approved Vraylar (cariprazine) \nas adjunctive therapy to antidepressants for the treatment of major \ndepressive...', 'thumbnail': 'https://serpapi.com/searches/6724ac381f3d4bf4cd7b3fd0/images/6474e965e2256fd70e9c1c4c1418d0c63a0d1abd582b8ef4c30be7634b919004.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8091797828674316}",,,,,,,,,,['neutral'],neutral,1 NCT04292899,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2015301', 'title': 'Remdesivir for 5 or 10 Days in Patients with Severe Covid-19', 'source': 'The New England Journal of Medicine', 'date': 'May 27, 2020', 'snippet': 'In patients with severe Covid-19 not requiring mechanical ventilation, our \ntrial did not show a significant difference between a 5-day course and a \n10-day...', 'thumbnail': 'https://serpapi.com/searches/6724aca58e13c9e2203a3a08/images/fbf0b027415a9e820c563b333377ca3b3209dd468b1929be3d1cbbf70d579ec3.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6665990948677063}",,,,,,,,,,['neutral'],neutral,1 NCT02481674,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-022-01919-8', 'title': 'Pepinemab antibody blockade of SEMA4D in early Huntington’s disease: a randomized, placebo-controlled, phase 2 trial', 'source': 'Nature', 'date': 'Aug 8, 2022', 'snippet': 'A multicenter, randomized, double-blind, placebo-controlled phase 2 study \n(no. NCT02481674) established to evaluate pepinemab, a semaphorin 4D \n(SEMA4D)-...', 'thumbnail': 'https://serpapi.com/searches/6724afecd9c3e602db8cb197/images/22dae4a967b61f6bd3d33ecf53e93399924635092c78a7f06a0d5a4467ca55b1.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8687688708305359}",,,,,,,,,,['neutral'],neutral,1 NCT00087867,"{'position': 1, 'link': 'https://www.science.org/doi/10.1126/scitranslmed.aaw8412', 'title': 'Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials', 'source': 'Science | AAAS', 'date': 'Sep 11, 2019', 'snippet': 'Ninety-seven percent of drug-indication pairs that are tested in clinical \ntrials in oncology never advance to receive U.S. Food and Drug...', 'thumbnail': 'https://serpapi.com/searches/6724afefbd7cf082585b2d78/images/2d1d4a011b038560b18c3a921927e2991be8e584a2504274893958225b39931a.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.7454726099967957}",,,,,,,,,,['negative'],negative,0 NCT00357669,"{'position': 1, 'link': 'https://www.ucb.com/clinical-studies/Clinical-studies-index/brivaracetam', 'title': 'Brivaracetam (Briviact®)', 'source': 'UCB', 'date': 'Aug 30, 2024', 'snippet': 'Epilepsy, A Study to Evaluate the Pharmacokinetics, Safety, and \nTolerability of Intravenous Brivaracetam in Subjects >= 1 Month to < 16...', 'thumbnail': 'https://serpapi.com/searches/6724b198a47167bf2db0b4de/images/6e84d2c7ba83962f317bc4ffe2e478e4dc63dae8645bf58e5346233b14fd5efb.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.901799738407135}",,,,,,,,,,['neutral'],neutral,1 NCT04816669,"{'position': 1, 'link': 'https://www.nature.com/articles/s41587-022-01294-2', 'title': 'The clinical progress of mRNA vaccines and immunotherapies', 'source': 'Nature', 'date': 'May 9, 2022', 'snippet': 'The emergency use authorizations (EUAs) of two mRNA-based severe acute \nrespiratory syndrome coronavirus (SARS-CoV)-2 vaccines approximately...', 'thumbnail': 'https://serpapi.com/searches/6724b19958e433512ffb0ab4/images/74f07323d03d2cb02014ad339235a4ed6ed2a76698108a73e60f7220c9fcfae3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.921474814414978}",,,,,,,,,,['neutral'],neutral,1 NCT00935012,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/10.1161/circheartfailure.117.004769', 'title': 'TTR (Transthyretin) Stabilizers Are Associated With Improved Survival in Patients With TTR Cardiac Amyloidosis', 'source': 'American Heart Association Journals', 'date': 'Apr 3, 2018', 'snippet': 'Background:TTR (transthyretin) cardiac amyloidosis is caused by \ndissociation of TTR into monomers, which misassemble into amyloid fibrils.', 'thumbnail': 'https://serpapi.com/searches/6724b1d80a545a517f22bcf7/images/fe7fdef8957f37b5a200bf734ab088c2dac0f2f37d7c2afbac607cef71c96b48.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8781768679618835}",,,,,,,,,,['neutral'],neutral,1 NCT03131570,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1250504/full', 'title': 'Multi-omics segregate different transcriptomic impacts of anti-IL-17A blockade on type 17 T-cells and regulatory immune cells in psoriasis skin', 'source': 'Frontiers', 'date': 'Sep 11, 2023', 'snippet': 'The purpose of the study was to find translational evidence that systemic \nIL-17A blockade promotes regulatory transcriptome modification in human \npsoriasis...', 'thumbnail': 'https://serpapi.com/searches/6724ad77e95dbf79479328cc/images/e052e3acbb68a4fbd9d4b55a7d1022a4157691e88214f36185060af34ad4a954.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8213093280792236}",,,,,,,,,,['neutral'],neutral,1 NCT02963506,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2017/12/20/bimekizumab-shows-promise-for-ankylosing-spondylitis-patients-in-phase-2b-trial/', 'title': 'Ankylosing Spondylitis Trial of Bimekizumab Shows Promise for Patients', 'source': 'Ankylosing Spondylitis News', 'date': 'Dec 20, 2017', 'snippet': ""UCB's bimekizumab shows significant improvements in symptoms of ankylosing \nspondylitis patients after 12 weeks of treatment in a Phase 2b..."", 'thumbnail': 'https://serpapi.com/searches/6724ad890f2a2c9de44be505/images/5b79d8a52a4e05a23478df9134f75f89d8c58c5e496de9449c60ecc7222d5705.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.6875741481781006}",,,,,,,,,,['positive'],positive,1 NCT03254758,"{'position': 1, 'link': 'https://onlinelibrary.wiley.com/doi/full/10.1002/cbin.11725', 'title': 'The role of mesenchymal stem cells in liver injury - Sun - 2022 - Cell Biology International', 'source': 'Wiley Online Library', 'date': 'Dec 9, 2021', 'snippet': 'Abstract Recently, mesenchymal stem cell (MSC) therapy has been suggested \nas an effective alternative approach for the treatment of hepatic...', 'thumbnail': 'https://serpapi.com/searches/6724af82e10f0a4d9ab9f8b2/images/9c006c85646bd206a3392369a4141222be083802d596cf51ff5b6565d9a1cd42.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9039925336837769}",,,,,,,,,,['neutral'],neutral,1 NCT00372593,"{'position': 1, 'link': 'https://www.nature.com/articles/s41698-024-00643-5', 'title': 'Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials | npj Precision Oncology', 'source': 'Nature', 'date': 'Aug 1, 2024', 'snippet': 'In this study, we leveraged machine-learning tools by evaluating expression \nof genes of pharmacological relevance to standard-AML...', 'thumbnail': 'https://serpapi.com/searches/6724af83e45f334645884051/images/720a0271d9626f7a3d0301b184f068462b681b843be6734e3e243fc89e16ab15.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.894627571105957}",,,,,,,,,,['neutral'],neutral,1 NCT02224560,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1714631', 'title': 'Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome', 'source': 'The New England Journal of Medicine', 'date': 'May 16, 2018', 'snippet': 'Cannabidiol has been used for treatment-resistant seizures in patients with \nsevere early-onset epilepsy. We investigated the efficacy and...', 'thumbnail': 'https://serpapi.com/searches/6724af8d24296af4b17607a6/images/7b58b2cf148021b01fe8afa29003e3fc1a98d6ed67c2131804a99c3311b79db6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8694579005241394}",,,,,,,,,,['neutral'],neutral,1 NCT01868997,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1614949', 'title': 'Teprotumumab for Thyroid-Associated Ophthalmopathy', 'source': 'The New England Journal of Medicine', 'date': 'May 4, 2017', 'snippet': 'In patients with active ophthalmopathy, teprotumumab was more effective \nthan placebo in reducing proptosis and the Clinical Activity Score.', 'thumbnail': 'https://serpapi.com/searches/6724acb7e10f0a4b53aabe00/images/5031f48ae2b256c8725b5db1a2a6327e5eb880ea2dce8edbb7567b44f5d54b48.png', 'sentiment': 'positive', 'sentiment_prob': 0.5693291425704956}","{'position': 2, 'link': 'https://www.nature.com/articles/s41433-021-01539-5', 'title': 'Teprotumumab for thyroid eye disease: early response is not required for benefit', 'source': 'Nature', 'date': 'Jun 28, 2021', 'snippet': 'In recent trials, 50% of patients treated with teprotumumab for thyroid eye \ndisease had significant improvements in proptosis at 6 weeks.', 'thumbnail': 'https://serpapi.com/searches/6724acb7e10f0a4b53aabe00/images/5031f48ae2b256c8c3200e7e94a8505579c9e212dc926c814ce0662fda45a96d.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5698319673538208}",,,,,,,,,"['positive', 'neutral']",positive,1 NCT02960581,"{'position': 1, 'link': 'https://www.nature.com/articles/s41591-021-01509-0', 'title': 'Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial', 'source': 'Nature', 'date': 'Oct 7, 2021', 'snippet': 'Human immunodeficiency virus (HIV)-1-specific broadly neutralizing \nmonoclonal antibodies are currently under development to treat and...', 'thumbnail': 'https://serpapi.com/searches/6724acbddc969f174722f880/images/07361dd61bbad045c128a8951d326f1379fbf8ec6f6d11e8ce88beb0f8f45b3a.png', 'sentiment': 'neutral', 'sentiment_prob': 0.846068799495697}",,,,,,,,,,['neutral'],neutral,1 NCT02435992,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2033617', 'title': 'Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis', 'source': 'The New England Journal of Medicine', 'date': 'Sep 29, 2021', 'snippet': 'We conducted a phase 3, multicenter, randomized, double-blind, \nplacebo-controlled trial of ozanimod as induction and maintenance therapy \nin...', 'thumbnail': 'https://serpapi.com/searches/6724acd4aab36d7f847b5045/images/623bbb75e30e9ab41b51015b26ebc5a3ba3bb6bb872ce175b721496d38ece6d6.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8953365683555603}","{'position': 2, 'link': 'https://ibdnewstoday.com/2021/01/04/eu-reviewing-zeposia-as-ulcerative-colitis-treatment-for-adults/', 'title': 'Zeposia Under Review in EU to Treat Active Ulcerative Colitis in Adults', 'source': 'ibdnewstoday.com', 'date': 'Jan 4, 2021', 'snippet': 'The anti-inflammatory medication Zeposia (ozanimod) is under review in the \nEuropean Union to treat ulcerative colitis in adults.', 'thumbnail': 'https://serpapi.com/searches/6724acd4aab36d7f847b5045/images/623bbb75e30e9ab4081b75d8cdbfab898b8d27973b2f8e07c31bb955f17426b1.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8333906531333923}","{'position': 3, 'link': 'https://ibdnewstoday.com/2020/10/19/zeposia-effective-in-keeping-ulcerative-colitis-in-remission-phase-3-ibd-study-shows/', 'title': 'Zeposia Effective in Keeping Ulcerative Colitis in Remission, Phase 3 Study Shows', 'source': 'ibdnewstoday.com', 'date': 'Oct 19, 2020', 'snippet': 'Zeposia, an investigational anti-inflammatory medicine, significantly \nincreased clinical remission in ulcerative colitis patients in a...', 'thumbnail': 'https://serpapi.com/searches/6724acd4aab36d7f847b5045/images/623bbb75e30e9ab488bf5763b14adf15259eb2d0c852ff5f538ef01accb16ad8.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.5019934177398682}",,,,,,,,"['neutral', 'neutral', 'positive']",neutral,1 NCT02680249,"{'position': 1, 'link': 'https://cysticfibrosisnewstoday.com/ctp-656-cystic-fibrosis/', 'title': 'VX-561 (Formerly CTP-656)', 'source': 'Cystic Fibrosis News Today', 'date': 'Aug 20, 2019', 'snippet': 'CTP-656, now known as VX-561, is the deuterated, or deuterium-modified form \nof Kalydeco (ivacaftor), an FDA-approved treatment for cystic fibrosis (CF).', 'thumbnail': 'https://serpapi.com/searches/6724acda8d04175e361fbe85/images/bb8431c34c87fe548f7b4412b7d465f678f61764f97c15ee23facbfd5ed2200a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.863865852355957}",,,,,,,,,,['neutral'],neutral,1 NCT02904954,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-023-44195-x', 'title': 'Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial', 'source': 'Nature', 'date': 'Dec 19, 2023', 'snippet': 'We previously reported the results of a randomized phase II trial \n(NCT02904954) in patients with early-stage non-small cell lung cancer...', 'thumbnail': 'https://serpapi.com/searches/6724ace668831e95e9de198c/images/0be472c84bf6cee26b915688f3a3df3bc1cb8f06985cfdc71c6a60b2dc834609.png', 'sentiment': 'neutral', 'sentiment_prob': 0.9007678627967834}",,,,,,,,,,['neutral'],neutral,1 NCT04032093,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2106062', 'title': 'Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy', 'source': 'The New England Journal of Medicine', 'date': 'Apr 27, 2022', 'snippet': 'Respiratory syncytial virus (RSV), a major cause of illness and death in \ninfants worldwide, could be prevented by vaccination during...', 'thumbnail': 'https://serpapi.com/searches/6724ad3598d8de07c2d59202/images/9b49bf11520e8bcb33c283eab00cac0f83c68f3785f363b5778a0e23076a6d9e.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6773319840431213}",,,,,,,,,,['negative'],negative,0 NCT04523207,"{'position': 1, 'link': 'https://www.targetedonc.com/view/studying-apalutamide-with-adt-in-high-risk-localized-prostate-cancer', 'title': 'Studying Apalutamide With ADT in High-Risk Localized Prostate Cancer', 'source': 'Targeted Oncology', 'date': 'Jun 20, 2024', 'snippet': 'Vitaly Margulis, MD, professor of urology at UT Southwestern Medical \nCenter, discusses the Apa-RP study (NCT04523207) of adjuvant treatment...', 'thumbnail': 'https://serpapi.com/searches/6724ad36b4e8d6b9b2dad243/images/370358015dddc4f6b7d56f26514f4fc872465de18a378a675a64d0b1949675fa.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9437883496284485}","{'position': 2, 'link': 'https://www.urologytimes.com/view/apalutamide-combo-hits-high-2-year-rfs-rate-in-prostate-cancer', 'title': 'Apalutamide combo hits high 2-year RFS rate in prostate cancer', 'source': 'Urology Times', 'date': 'May 3, 2024', 'snippet': 'Treatment with apalutamide and androgen deprivation therapy led to a 2-year \nbiochemical recurrence-free survival rate of 100% in patients...', 'thumbnail': 'https://serpapi.com/searches/6724ad36b4e8d6b9b2dad243/images/370358015dddc4f63ecd22d3cad3c250ff48b27f93c21c94200702e39705d301.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8000161647796631}",,,,,,,,,"['neutral', 'neutral']",neutral,1 NCT01004991,"{'position': 1, 'link': 'https://www.nature.com/articles/bcj201765', 'title': 'Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells | Blood Cancer Journal', 'source': 'Nature', 'date': 'Jul 21, 2017', 'snippet': 'The Ten Eleven Translocation (TET) enzymes have been found to be mutated in \nboth diffuse large B-cell (DLBCL) and peripheral T-cell (PTCL)...', 'thumbnail': 'https://serpapi.com/searches/6724ad61c117a9b6706ca1b3/images/d8e8624e4f4d3c29b4e6d31b96d8d85949bf2d88b4fae80e42d67f96a96b4f5b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6271765232086182}",,,,,,,,,,['neutral'],neutral,1 NCT01584440,"{'position': 1, 'link': 'https://alzheimersnewstoday.com/news/avp-786-fails-ease-alzheimers-related-agitation-phase-3-trial/', 'title': 'AVP-786 fails to ease Alzheimer’s-related agitation in Phase 3 trial', 'source': ""Alzheimer's News Today"", 'date': 'Feb 29, 2024', 'snippet': ""A Phase 3 clinical trial of AVP-786 failed to meet its main goal of easing \nagitation in adults with dementia due to Alzheimer's disease."", 'thumbnail': 'https://serpapi.com/searches/6724ae5dd997abefdfc4f9da/images/f4d741efbda300496ab16c908debb685b9b03f8aec7694f6368389a74f3ea36b.png', 'sentiment': 'negative', 'sentiment_prob': 0.8483138084411621}",,,,,,,,,,['negative'],negative,0 NCT03486834,"{'position': 1, 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We \npresent different aspects of the disease, from cellular and inflammatory \nresponses to...', 'thumbnail': 'https://serpapi.com/searches/6724ba28ee468238b3e0630e/images/f84737bd0a7df13d7693ed62743f95e1468baf226e26031e7d346fb0bcddd56a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.930492639541626}",,,,,,,,,,['neutral'],neutral,1 NCT02760498,"{'position': 1, 'link': 'https://www.onclive.com/view/cemiplimab-monotherapy-continues-to-generate-responses-in-locally-advanced-or-metastatic-cscc', 'title': 'Cemiplimab Monotherapy Continues to Generate Responses in Locally Advanced or Metastatic CSCC', 'source': 'OncLive', 'date': 'Oct 25, 2022', 'snippet': 'Single-agent cemiplimab demonstrated safety and efficacy in patients with \nlocally advanced or metastatic cutaneous squamous cell carcinoma...', 'thumbnail': 'https://serpapi.com/searches/6724ba317b05cab001f2bbe5/images/cb2a8b7373ed7547b635cb8e7a7bd27ea33517476cc86335fd4e1bd50a350ce3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 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gene therapy intended to treat dystrophic epidermolysis \nbullosa (DEB), has been validated by the European Medicines Agency's (EMA) \nCommittee..."", 'thumbnail': 'https://serpapi.com/searches/6724ba3d66d9955adeca3b25/images/c3be17e54dfe454ee277542d42244cad9cba23f2ec4004dff35c85a5a668fa6f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8852711319923401}","{'position': 3, 'link': 'https://epidermolysisbullosanews.com/news/phase-3-deb-trial-testing-topical-gene-therapy-b-vec-now-complete/', 'title': 'Phase 3 DEB Trial Testing Topical Gene Therapy B-VEC Now Complete', 'source': 'Epidermolysis Bullosa News', 'date': 'Nov 5, 2021', 'snippet': 'A Phase 3 clinical trial testing B-VEC (beremagene geperpavec), a topical \ngene therapy for treating skin wounds in patients with dystrophic \nepidermolysis...', 'thumbnail': 'https://serpapi.com/searches/6724ba3d66d9955adeca3b25/images/c3be17e54dfe454e6865c592afd584aa8d25c4fe37d55adeea6b2af55ecde94e.png', 'sentiment': 'neutral', 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LC350189 achieved a treatment target of sUA < 5...', 'thumbnail': 'https://serpapi.com/searches/6724ba56a5d702549f3682fe/images/3b379054c007da1a8e704533807c7a05e6de222e7551fa65515dbbecb3a657e4.png', 'sentiment': 'positive', 'sentiment_prob': 0.756885290145874}",,,,,,,,,,['positive'],positive,1 NCT02916537,"{'position': 1, 'link': 'https://www.businesswire.com/news/home/20170412005094/en/Cancer-Targeted-Technology-Announces-Advances-with-its-PSMA-targeted-PET-Imaging-and-Radiotherapeutic-Agents-for-Prostate-Cancer-at-Upcoming-Conferences', 'title': 'Cancer Targeted Technology Announces Advances with its PSMA-targeted PET Imaging and Radiotherapeutic Agents for Prostate Cancer at Upcoming Conferences', 'source': 'Business Wire', 'date': 'Apr 12, 2017', 'snippet': 'Cancer Targeted Technology presents data on its PET imaging agent, CTT1057, \nfrom a prostate cancer clinical trial, and its radiotherapeutic...', 'thumbnail': 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vaccine axalimogene filolisbac, also \nknown as ADXS11-001 or AXAL, to be well tolerated at higher doses.', 'thumbnail': 'https://serpapi.com/searches/6724b6cf6de1e4f859151213/images/046884a4ba931ac9694e91d46bdad399df01c8700d9a73fa1d7ea3b3a5fba157.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.4984729588031769}",,,,,,,,,"['neutral', 'positive']",neutral,1 NCT04711005,"{'position': 1, 'link': 'https://www.nimh.nih.gov/news/science-news/2024/new-hope-for-rapid-acting-depression-treatment', 'title': 'New Hope for Rapid-Acting Depression Treatment', 'source': 'National Institute of Mental Health (NIMH) (.gov)', 'date': '1 week ago', 'snippet': 'A new study, funded in part by the National Institute of Mental Health, \nshowed that a new medication derived from ketamine is safe and...', 'thumbnail': 'https://serpapi.com/searches/6724b3fea8827886cf8fc7a8/images/eba1184900aaf080cc150b8f1dc0f28721b61c2a22e6e5b697b730e9367c3f6f.jpeg', 'sentiment': 'positive', 'sentiment_prob': 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\nthymectomies in myasthenia gravis patients, a Singapore study...', 'thumbnail': 'https://serpapi.com/searches/6724b3ff5c7cb95e509264bc/images/74f19a3dc6a1403d7d77025f432e8ab880c56e39d2a39e085c31171df321d7a3.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6862289309501648}","{'position': 3, 'link': 'https://myastheniagravisnews.com/news/clinical-trial-shows-thymus-surgery-helps-myasthenia-gravis-patients-more-than-medicine/', 'title': 'Myasthenia Gravis Patients Do Better with Thymus Surgery, Trial Reports', 'source': 'Myasthenia Gravis News', 'date': 'Jul 20, 2017', 'snippet': 'Read about a Phase 3 clinical trial showing that thymus surgery plus \nmedicine is better than medicine alone as a treatment for myasthenia...', 'thumbnail': 'https://serpapi.com/searches/6724b3ff5c7cb95e509264bc/images/74f19a3dc6a1403dc00a1cb7b0f2de15d887af1cc93ce077972066089f7de756.jpeg', 'sentiment': 'positive', 'sentiment_prob': 0.7658814787864685}",,,,,,,,"['positive', 'neutral', 'positive']",positive,1 NCT02167139,"{'position': 1, 'link': 'https://ankylosingspondylitisnews.com/2022/08/18/fda-approves-higher-concentration-hadlima-humira-biosimilar/', 'title': 'FDA Approves Higher Concentration of Hadlima, a Humira Biosimilar...', 'source': 'Ankylosing Spondylitis News', 'date': 'Aug 18, 2022', 'snippet': ""The US Food and Drug Administration (FDA) has approved a new, more highly \nconcentrated formulation of Hadlima (adalimumab-bwwd), a biosimilar to \nAbbVie's..."", 'thumbnail': 'https://serpapi.com/searches/6724b456e30abc8b5967ef2c/images/7d1248b28f50ad1d98cb02bc3cd21b8486e49ef6286c674a5d6b4c5e2ebe7920.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5983152985572815}",,,,,,,,,,['neutral'],neutral,1 NCT04603027,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1292406/full', 'title': 'A randomized, double-blinded, phase 2 trial of EDP1815, an oral immunomodulatory preparation of Prevotella histicola, in adults with mild-to-moderate plaque psoriasis', 'source': 'Frontiers', 'date': 'May 14, 2024', 'snippet': '1Oregon Medical Research Center, Portland, OR, United States; 2Yale \nUniversity School of Medicine, New Haven, CT, United States...', 'thumbnail': 'https://serpapi.com/searches/6724b45eba13f2dee66bc7db/images/5ebeffc95034be016f182d23354a04d71fef1c8fd91a186a455ba44e997a767a.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9029088020324707}",,,,,,,,,,['neutral'],neutral,1 NCT02939391,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/kyowa-kirin-stops-kw-6356-program-despite-promising-phase-2-results/', 'title': 'Kyowa Kirin Stops KW-6356 Program Despite Promising Phase 2 Results', 'source': ""Parkinson's News Today"", 'date': 'Jul 25, 2022', 'snippet': ""Kyowa Kirin is terminating the clinical development program for KW-6356, \nits investigational treatment for Parkinson's disease."", 'thumbnail': 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promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer', 'source': 'Nature', 'date': 'Sep 16, 2020', 'snippet': 'Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. \nDue to their HLA-independent mode of action, allogeneic Vγ9Vδ2 T...', 'thumbnail': 'https://serpapi.com/searches/6724b54d8a7c09edb272e583/images/92cf414377f6b226c3841334fd6eac4e5b41301de971af765e881c35dcb280a3.png', 'sentiment': 'positive', 'sentiment_prob': 0.7890372276306152}",,,,,,,,,,['positive'],positive,1 NCT04551534,"{'position': 1, 'link': 'https://parkinsonsnewstoday.com/news/potential-parkinsons-therapy-dnl201-safely-targets-enzyme-studies/', 'title': ""Potential Parkinson's Therapy DNL201 Safely Targets Enzyme: Studies"", 'source': ""Parkinson's News Today"", 'date': 'Jun 23, 2022', 'snippet': ""DNL201, an investigational therapy for Parkinson's, was tolerated in \nhealthy volunteers and patients, and engaged with the LRRK2 protein."", 'thumbnail': 'https://serpapi.com/searches/6724b589db3ac996fe588f02/images/423b82dbf6e548fb92ccd32c474627e3b52eeea06cbc6bb8e15d8f8e292b1693.png', 'sentiment': 'neutral', 'sentiment_prob': 0.5823979377746582}",,,,,,,,,,['neutral'],neutral,1 NCT01202591,"{'position': 1, 'link': 'https://www.nature.com/articles/s41467-022-30666-0', 'title': 'Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer', 'source': 'Nature', 'date': 'Jun 10, 2022', 'snippet': 'We conducted a phase IIa, multi-centre, open label, single arm study \n(RADICAL; NCT01791985) of AZD4547 (a potent and selective inhibitor of...', 'thumbnail': 'https://serpapi.com/searches/6724b49848c4295adb38cf44/images/c72f0ea103ced71a4258df91537a39387f329823008a41397ed63d4e509eba03.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8903841972351074}",,,,,,,,,,['neutral'],neutral,1 NCT02065557,"{'position': 1, 'link': 'https://ibdnewstoday.com/ibd-treatment/humira-adalimumab/', 'title': 'Range of Bowel Diseases Can Be Treated with Humira', 'source': 'ibdnewstoday.com', 'date': 'Aug 31, 2017', 'snippet': 'Humira (adalimumab) is a biological therapy that the US Food and Drug \nAdministration approved for treating inflammatory bowel disease, or IBD.', 'thumbnail': 'https://serpapi.com/searches/6724b4aa0c666878cdff8f39/images/3537412aa6578c8ecd3ae42bc8da55b24d73d907198f8017a1119c5a1d9f86ba.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.9108577370643616}",,,,,,,,,,['neutral'],neutral,1 NCT01245062,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa1203421', 'title': 'Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma', 'source': 'The New England Journal of Medicine', 'date': 'Jun 4, 2012', 'snippet': 'Activating mutations in serine–threonine protein kinase B-RAF (BRAF) are \nfound in 50% of patients with advanced melanoma.', 'thumbnail': 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Traditional smallpox vaccines are based on...', 'thumbnail': 'https://serpapi.com/searches/6724b4d449ea557bf0b6e171/images/6236677fee46f11fc33be506fc4e57a0aa73f4d907d851dd65805718b54bd697.png', 'sentiment': 'neutral', 'sentiment_prob': 0.8469113111495972}",,,,,,,,,,['neutral'],neutral,1 NCT04666298,"{'position': 1, 'link': 'https://www.nature.com/articles/s41392-023-01690-3', 'title': 'Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): from bench to bedside', 'source': 'Nature', 'date': 'Jan 8, 2024', 'snippet': 'Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a \npivotal enzyme in lipid metabolism and a revolutionary therapeutic...', 'thumbnail': 'https://serpapi.com/searches/6724b4d6c4bcf5253169013a/images/9aecfe465cae530ac9b49ebfeabde3f8f91cf157ba07e427710d56373159248b.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6380511522293091}",,,,,,,,,,['neutral'],neutral,1 NCT03296696,"{'position': 1, 'link': 'https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1255611/full', 'title': 'Immunotherapy: a promising approach for glioma treatment', 'source': 'Frontiers', 'date': 'Feb 8, 2024', 'snippet': 'Gliomas are the most prevalent primary malignant brain tumors worldwide, \nwith glioblastoma (GBM) being the most common and aggressive type.', 'thumbnail': 'https://serpapi.com/searches/6724b4e8e45f334645884124/images/90bc9201632a6f983abc895482f0d2c4606864508d8480e0d6b672dd93e4e5b9.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6341026425361633}",,,,,,,,,,['neutral'],neutral,1 NCT03104413,"{'position': 1, 'link': 'https://ibdnewstoday.com/2021/01/18/risankizumab-induces-clinical-endoscopic-remission-after-12-weeks-in-crohns-disease-clinical-trials/', 'title': ""Crohn's Remission Shown After 12 Weeks in Risankizumab Clinical Trial"", 'source': 'ibdnewstoday.com', 'date': 'Jan 18, 2021', 'snippet': ""Treatment with risankizumab for 12 weeks induced both clinical and 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'Aug 15, 2023', 'snippet': 'The US Food and Drug Administration (FDA) has issued a complete response \nletter to Galera Therapeutics related to the new drug application for \navasopasem...', 'thumbnail': 'https://serpapi.com/searches/6724b514a8692161d8caa8db/images/0f27a7a4b20db85b9d3b61c092eda32d078f96e0e03416f831a4c1c0833ca3b7.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.5011367201805115}",,,,,,,,,,['neutral'],neutral,1 NCT02970942,"{'position': 1, 'link': 'https://www.nejm.org/doi/full/10.1056/NEJMoa2028395', 'title': 'A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis', 'source': 'The New England Journal of Medicine', 'date': 'Nov 13, 2020', 'snippet': 'This phase 2 trial involving patients with NASH showed that treatment with \nsemaglutide resulted in a significantly higher percentage of patients with \nNASH...', 'thumbnail': 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'source': 'The New England Journal of Medicine', 'date': 'Mar 28, 2020', 'snippet': 'Patients with peripheral artery disease who have undergone lower-extremity \nrevascularization are at high risk for major adverse limb and \ncardiovascular...', 'thumbnail': 'https://serpapi.com/searches/6724b5aac7d4a15132363d25/images/a142e72b22f41a142e544fd10a86a0b0e4a95bb0099f2a191e21c675471edd25.png', 'sentiment': 'neutral', 'sentiment_prob': 0.6069828867912292}",,,,,,,,,,['neutral'],neutral,1 NCT04173494,"{'position': 1, 'link': 'https://www.hematologyadvisor.com/cch/ojjaara-for-intermediate-or-high-risk-myelofibrosis/', 'title': 'Ojjaara for Intermediate or High-Risk Myelofibrosis', 'source': 'Hematology Advisor', 'date': 'Sep 18, 2023', 'snippet': 'In September 2023, the US Food and Drug Administration (FDA) approved \nOjjaara (momelotinib; GlaxoSmithKline), a kinase inhibitor,...', 'thumbnail': 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Gerds, MD, MS, unpacks data seen with momelotinib for patients \nwith anemic myelofibrosis.', 'thumbnail': 'https://serpapi.com/searches/6724b5b9bcd6529295704a3b/images/544916e16adb36e85a0edfd5856779316e40c2af9df62eb699c5fc6161e1242f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.913780152797699}","{'position': 3, 'link': 'https://www.cancernetwork.com/view/momelotinib-receives-fda-approval-for-myelofibrosis-with-anemia', 'title': 'Momelotinib Receives FDA Approval for Myelofibrosis With Anemia', 'source': 'Cancer Network', 'date': 'Sep 15, 2023', 'snippet': 'The FDA has approved momelotinib (Ojjaara) for the treatment of patients \nwith intermediate- or high-risk myelofibrosis, including primary and \nsecondary...', 'thumbnail': 'https://serpapi.com/searches/6724b5b9bcd6529295704a3b/images/544916e16adb36e82407f91018951f5af9cf6efa1a2b3e4175f56676dfab91e2.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8063039183616638}",,,,,,,,"['neutral', 'neutral', 'neutral']",neutral,1 NCT05322473,"{'position': 1, 'link': 'https://www.termedia.pl/Hidradenitis-suppurativa-a-new-therapeutic-approach-for-an-old-disease,7,54608,1,1.html', 'title': 'Hidradenitis suppurativa: a new therapeutic approach for an old disease', 'source': 'Termedia', 'date': 'Aug 12, 2024', 'snippet': 'Hidradenitis suppurativa (HS) is a chronic inflammatory disease \ncharacterised by recurrent painful nodules, abscesses, fistulas and \nscarring...', 'thumbnail': 'https://serpapi.com/searches/6724b5c5d0c983dd0f53c76a/images/f603b6aab4454eda70b2e3fcbac1971207424e277904b25d1d5995df51ccd418.jpeg', 'sentiment': 'negative', 'sentiment_prob': 0.6704685091972351}",,,,,,,,,,['negative'],negative,0 NCT04279613,"{'position': 1, 'link': 'https://www.nature.com/articles/s41435-023-00221-y', 'title': 'IL-2 immunotherapy for targeting regulatory T cells in autoimmunity', 'source': 'Nature', 'date': 'Sep 23, 2023', 'snippet': 'A new and promising focus in drug development are IL-2-based approaches for \nin vivo targeted expansion of T reg or for enhancement of their \nsuppressive...', 'thumbnail': 'https://serpapi.com/searches/6724b5d62c83d523bce210e8/images/35f4ea24dffbed6700751784fe8a97c4dc305a52120c340b41592e335cede424.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.6119940280914307}",,,,,,,,,,['neutral'],neutral,1 NCT04674761,"{'position': 1, 'link': 'https://www.empr.com/home/news/bylvay-approved-for-cholestatic-pruritus-due-to-alagille-syndrome/', 'title': 'Bylvay Approved for Cholestatic Pruritus Due to Alagille Syndrome', 'source': 'Medical Professionals Reference', 'date': 'Jun 14, 2023', 'snippet': 'The Food and Drug Administration (FDA) has approved Bylvay (odevixibat) for \nthe treatment of cholestatic pruritus in patients 12 months of age and \nolder with...', 'thumbnail': 'https://serpapi.com/searches/6724b5df708e2e0aabc4b0db/images/6484d2857d906b5d6e994432ada786b9687ee017870e2d2fa7afdc0c055f034f.jpeg', 'sentiment': 'neutral', 'sentiment_prob': 0.8768388628959656}",,,,,,,,,,['neutral'],neutral,1 NCT00132470,"{'position': 1, 'link': 'https://www.ahajournals.org/doi/full/10.1161/strokeaha.110.579508', 'title': 'AXIS | Stroke', 'source': 'American Heart Association Journals', 'date': 'Oct 14, 2010', 'snippet': 'Background and Purpose—Granulocyte colony-stimulating factor (G-CSF) is a \npromising stroke drug candidate. The present phase IIa study...', 'thumbnail': 'https://serpapi.com/searches/6724b606ba11427ba37ffd12/images/b288402b58b432ecbb7a5bf930ccf25f001dcf8d6efe9569aa2a5cc92e022408.png', 'sentiment': 'neutral', 'sentiment_prob': 0.7770700454711914}",,,,,,,,,,['neutral'],neutral,1 NCT01469377,"{'position': 1, 'link': 'https://www.psychiatrist.com/jcp/efficacy-safety-adjunctive-cariprazine-inadequate/', 'title': 'Efficacy and Safety of Adjunctive Cariprazine in Inadequate Responders to Antidepressants: A Randomized, Double-Blind, Placebo-Controlled Study in Adult Patients With Major Depressive Disorder', 'source': 'Psychiatrist.com', 'date': 'Mar 23, 2016', 'snippet': 'These results show that adjunctive cariprazine 2–4.5 mg/d was effective and \ngenerally well tolerated in adults with MDD who had inadequate responses \nto...', 'thumbnail': 'https://serpapi.com/searches/6724b61a08abe491c5adc7fa/images/b851d9b9df9ee61c5364264c0b9d5ead7f69d1d89d76a014f363d26609570708.jpeg', 'sentiment': 'neutral', 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