press_release_conclusion: Antibiotics can still kill drug-resistant bacteria if they 'push' hard enough into bacterial cells, finds new UCL-led research funded by the Engineering and Physical Sciences Research Council.
abstract_conclusion: We examined the surface forces generated by four antibiotics; vancomycin, ristomycin, chloroeremomycin and oritavancin against drug-susceptible and drug-resistant targets on a cantilever and demonstrated significant differences in mechanical response when drug-resistant targets are challenged with different antibiotics although no significant differences were observed when using susceptible targets.