press_release_conclusion: Researchers at the Universities of Edinburgh and Tokyo have found that building on existing knowledge activates a key set of genes in the brain.
abstract_conclusion: In experiments with rats, we found that the hippocampal-dependent learning of new paired associates is associated with a striking up-regulation of immediate early genes in the prelimbic region of the medial prefrontal cortex, and that pharmacological interventions targeted at that area can prevent both new learning and the recall of remotely and even recently consolidated information.