press_release_conclusion: Many pain-sensing nerves in the body are thought to respond to all types of ‘painful events’, but new UCL research in mice reveals that in fact most are specialised to respond to specific types such as heat, cold or mechanical pain.
abstract_conclusion: After intraplantar treatment with prostaglandin E2, neurons in vivo respond more intensely to noxious thermal and mechanical stimuli, and additional neurons (silent nociceptors) are unmasked.