News Finding: 'While this observation supports the significance of our findings, at the moment we don't know if annexin-A6 has any pro-metastatic activity in human breast cancer,' Professor De Palma added.
Paper Finding: Both PTX and doxorubicin (DOX)-an anthracycline also used in breast cancer therapy 6 -increased the ability of perivascular TIE2
News Context: They hope this will improve the effectiveness of neoadjuvant therapy. 'While this observation supports the significance of our findings, at the moment we don't know if annexin-A6 has any pro-metastatic activity in human breast cancer,' Professor De Palma added. The authors also stress their findings should not discourage people from receiving neoadjuvant chemo when it is needed.
Paper Context: N eoadjuvant chemotherapy provides long-term clinical benefits to patients diagnosed with invasive breast cancer, especially when the primary tumour fully regresses before surgery . Both PTX and doxorubicin (DOX)-an anthracycline also used in breast cancer therapy 6 -increased the ability of perivascular TIE2 PTX enhances pulmonary metastasis in mouse mammary tumour models.