News Finding: This is not good enough and so we are delighted to support this research that has led to these fascinating findings.
Paper Finding: Anti-inflammatory activity of cordycepin is evident in murine macrophages in vitro and attributed to the repression of NF-ĸB dependent gene expression .
News Context: The results from this new research provides the possibility of a more effective treatment for osteoarthritis suffers that is less toxic, so will have reduced side effects for patients. This is not good enough and so we are delighted to support this research that has led to these fascinating findings. Although in its early stages, the study has great potential for helping people suffering pain of musculoskeletal conditions and demonstrates the high value and impact of novel discovery-led research on understanding and treating diseases."
Paper Context: Synovial inflammation is associated with cartilage damage and bone changes in OA, and is significantly associated with joint pain. Anti-inflammatory activity of cordycepin is evident in murine macrophages in vitro and attributed to the repression of NF-ĸB dependent gene expression . Identification of the mechanisms driving synovial inflammation have the potential to reveal new targets to relieve OA pain.