News Finding: RT Going from 2 X's to 1: Mammalian X inactivation relies on stepwise folding of #chromosome compartments aided by SMCHD1  MGH_RI harvardmed HHMINEWS 
Paper Finding: With its ATPase domain Chen et al., 2016) , SMCHD1 might serve as Xist's engine to drive attenuation of both compartments and TADs to complete the final Xi transformation.
News Context: RT Going from 2 X's to 1: Mammalian X inactivation relies on stepwise folding of #chromosome compartments aided by SMCHD1  MGH_RI harvardmed HHMINEWS 
Paper Context: This idea is supported by the nearly homogeneous distribution of SMCHD1 on the Xi, contacting both S1 and S2 compartments ( Figure 6 ). With its ATPase domain Chen et al., 2016) , SMCHD1 might serve as Xist's engine to drive attenuation of both compartments and TADs to complete the final Xi transformation. Future work will test our stepwise folding Origami Model.