News Finding: SPINART 3 year randomised study Tertiary Prophy vs On demand in adults with #haemophilia. With prophy 94% less bleeds. 1/3 no bleeds at all, 3/4 &lt;2 bleeds per year. Higher quality of life. No change in MRI - bony changes are irreversible.  #hemophilia
Paper Finding: Conclusions: Over a period of 3 years, prophylaxis versus OD in adults with severe hemophilia A and arthropathy led to decreased bleeding, pain, and HRU, better joint health, activity, satisfaction, and HRQoL, but no reduction in structural arthropathy progression, suggesting that preexisting joint arthropathy may be irreversible.
News Context: SPINART 3 year randomised study Tertiary Prophy vs On demand in adults with #haemophilia. With prophy 94% less bleeds. 1/3 no bleeds at all, 3/4 &lt;2 bleeds per year. Higher quality of life. No change in MRI - bony changes are irreversible.  #hemophilia
Paper Context: • Prophylaxis improved function, quality of life, activity and pain but not joint structure by MRI. Conclusions: Over a period of 3 years, prophylaxis versus OD in adults with severe hemophilia A and arthropathy led to decreased bleeding, pain, and HRU, better joint health, activity, satisfaction, and HRQoL, but no reduction in structural arthropathy progression, suggesting that preexisting joint arthropathy may be irreversible. • Prophylaxis improved function, quality of life, activity and pain but not joint structure by MRI.