News Finding: Synergistic effect of Aβ burden and Framingham (vascular disease) risk score ( on cognitive decline in normal older adults:
  
Paper Finding: Vascular risk maintained a strong association with cognitive decline beyond that of commonly used imaging biomarkers, including β-amyloid, hippocampal volume, fludeoxyglucose F18-labeled positron emission tomography, and white matter hyperintensities.
News Context: Synergistic effect of Aβ burden and Framingham (vascular disease) risk score ( on cognitive decline in normal older adults:
  
Paper Context: Findings In this study, Framingham and other vascular risk algorithms were associated with longitudinal cognitive decline, both alone and synergistically with β-amyloid burden. Vascular risk maintained a strong association with cognitive decline beyond that of commonly used imaging biomarkers, including β-amyloid, hippocampal volume, fludeoxyglucose F18-labeled positron emission tomography, and white matter hyperintensities. Meaning Vascular risk may complement other imaging biomarkers in assessing risk of cognitive decline in older adults with preclinical Alzheimer disease.