News Finding: Our new study just out in @username on how a #helminth #parasite infection hinders co-infection witb #prions. Great collaboration with Rick Maizels @username 
   #intestine #parasitology #prion #OperaAwards2019 #dendriticcells
Paper Finding: Since the lambs in the above study 65 were co-infected with T. circumcincta long after prion neuroinvasion from the intestine is likely to have occurred 62 , the reduced survival times are unlikely to be a consequence of effects of the parasite infection on the uptake or accumulation of the prions within the GALT.
News Context: Our new study just out in @username on how a #helminth #parasite infection hinders co-infection witb #prions. Great collaboration with Rick Maizels @username 
   #intestine #parasitology #prion #OperaAwards2019 #dendriticcells
Paper Context: Treatments that can delay the accumulation of prions in the GALT do not influence disease pathogenesis once neuroinvasion has occurred and the prions have established infection in the peripheral nervous system 5 . Since the lambs in the above study 65 were co-infected with T. circumcincta long after prion neuroinvasion from the intestine is likely to have occurred 62 , the reduced survival times are unlikely to be a consequence of effects of the parasite infection on the uptake or accumulation of the prions within the GALT. However, it is plausible that the parasite-mediated damage to the abomasum stimulated the systemic release of inflammatory mediators that exacerbated the development of neuropathology within the CNS 68 .