News Finding: They hope this will improve the effectiveness of neoadjuvant therapy.
Paper Finding: In particular, PTX increased the incidence (Fig.
News Context: When the researchers neutralised annexin-A6 or blocked the monocytes, the experimental breast tumour no longer spread to the lungs. They hope this will improve the effectiveness of neoadjuvant therapy. 'While this observation supports the significance of our findings, at the moment we don't know if annexin-A6 has any pro-metastatic activity in human breast cancer,' Professor De Palma added.
Paper Context: However, it resulted in increased pulmonary tumour deposits in a fraction of the mice, in line with previous findings . In particular, PTX increased the incidence (Fig. 1f,g ) and mean size (Fig.