News Finding: Possible mechanism behind #sleep defects in #FragileX and #autism 
Paper Finding: Conceivably, this means that subtle defects in neuronal ensemble dynamics that alter spontaneous replay and learning, particularly at early stages of cortical development, could result in intellectual dysfunction or autism.
News Context: Possible mechanism behind #sleep defects in #FragileX and #autism 
Paper Context: For example, sleep replay of awake experience in the cortex is probably critical for memory consolidation 4 . Conceivably, this means that subtle defects in neuronal ensemble dynamics that alter spontaneous replay and learning, particularly at early stages of cortical development, could result in intellectual dysfunction or autism. Such hyperexcitability could be triggered by defects in how network activity emerges in the cortex during development 15 or how it is modulated by different behavioral brain states .