News Finding: Using the pure extractions of each protein, Petry's team was able to see that in a test tube, neither protein can nucleate microtubules without the other.
Paper Finding: 8C) .
News Context: This was chiefly the contribution of Rachel Kadzik, a postdoctoral researcher in Petry's lab and a co-first-author on the paper who purified the g-TuRC and, with Thawani, purified the XMAP215. Using the pure extractions of each protein, Petry's team was able to see that in a test tube, neither protein can nucleate microtubules without the other. "If we take XMAP215 out, not a single microtubule forms.
Paper Context: 7 and Supplementary Fig. 8C) . Surprisingly, the C-terminal construct containing TOG5 and the C-terminal domain (TOG5-CT) strongly shifted γ -tubulin to an earlier elution volume, similar to the full-length XMAP215 (Fig.