News Finding: "The identification and characterization of CD8 T cell epitopes in mice immunized with a Zika RNA vaccine is a very useful
Paper Finding: Additional bands (indicated by asterisks) were detected that may correspond to incompletely processed ZIKV E protein.
News Context: They identified a sequence of eight amino acids that the activated T cells in the mouse respond to. Now that this sequence, also called an epitope, is known, other researchers can use it to test their own experimental Zika vaccines in the appropriate mouse models. "The identification and characterization of CD8 T cell epitopes in mice immunized with a Zika RNA vaccine is a very useful
Paper Context: Expression of the expected ~54 kDa protein product was observed ( Fig. Additional bands (indicated by asterisks) were detected that may correspond to incompletely processed ZIKV E protein. The full-length prM-E polyprotein segment encoded in the replicon has a predicted molecular weight of 73.4 kDa after signal peptidase processing to release the prM N-terminus.