News Finding: "Restoring function might require a person to generate a new pattern of neural activity.
Paper Finding: Within-manifold perturbations altered the relationship between factors and cursor kinematics.
News Context: "These findings could be the basis for novel rehabilitation procedures for the many neural disorders that are characterized by improper neural activity," Yu says. "Restoring function might require a person to generate a new pattern of neural activity. We could use techniques similar to what were used in this study to coach patients to generate proper neural activity."
Paper Context: We can expressx t in terms of the decoded velocity at the previous time stepx t{1 and the current z-scored spike count vector u t : Within-manifold perturbations altered the relationship between factors and cursor kinematics. This preserves the relationship between neural units and the intrinsic manifold, but changes the relationship between dimensions of the intrinsic manifold and cursor velocity.