Species
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values | eccDNA ID
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14
| Genome version
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values | Location
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25
| Chr
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float64 1
249M
⌀ | End
float64 1.47k
249M
⌀ | Health/Disease
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56
| Disease Name
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51
| Experiment/Prediction
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141
| Treatment
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237
| Source
stringlengths 13
295
| Library type
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| Public Date
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494
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2.89k
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Homo sapiens | ecDNA | ec_hsa_501 | hg19 | chr5:15720175-16140433 | chr5 | 15,720,175 | 16,140,433 | Disease | Brain | Glioblastoma | Experiment | FISH&Quantitative PCR&Chromosome Walking | Not Available | Not Available | By literature | Not Available | 20056677 | 2010 | Copy number amplification | This amplicon together with multiple chromosome segments to form the ecDNA:chr5:11153687-13433241,chr9:14439810-15510315,chr9:2561839-2986369,chr5:56354804-56497898,chr5:1104330-1300928. |
Homo sapiens | ecDNA | ec_hsa_502 | hg19 | chr9:2561839-2986369 | chr9 | 2,561,839 | 2,986,369 | Disease | Brain | Glioblastoma | Experiment | FISH&Quantitative PCR&Chromosome Walking | Not Available | Not Available | By literature | Not Available | 20056677 | 2010 | Copy number amplification | This amplicon together with multiple chromosome segments to form the ecDNA:chr5:11153687-13433241,chr9:14439810-15510315,chr5:15720175-16140433,chr5:56354804-56497898,chr5:1104330-1300928. |
Homo sapiens | ecDNA | ec_hsa_503 | hg19 | chr5:56354804-56497898 | chr5 | 56,354,804 | 56,497,898 | Disease | Brain | Glioblastoma | Experiment | FISH&Quantitative PCR&Chromosome Walking | Not Available | Not Available | By literature | Not Available | 20056677 | 2010 | Copy number amplification | This amplicon together with multiple chromosome segments to form the ecDNA:chr5:11153687-13433241,chr9:14439810-15510315,chr5:15720175-16140433,chr9:2561839-2986369,chr5:1104330-1300928. |
Homo sapiens | ecDNA | ec_hsa_504 | hg19 | chr5:1104330-1300928 | chr5 | 1,104,330 | 1,300,928 | Disease | Brain | Glioblastoma | Experiment | FISH&Quantitative PCR&Chromosome Walking | Not Available | Not Available | By literature | Not Available | 20056677 | 2010 | Copy number amplification | This amplicon together with multiple chromosome segments to form the ecDNA:chr5:11153687-13433241,chr9:14439810-15510315,chr5:15720175-16140433,chr9:2561839-2986369,chr5:56354804-56497898. |
Homo sapiens | ecDNA | ec_hsa_505 | hg19 | chr8:128032011-128806493 | chr8 | 128,032,011 | 128,806,493 | Disease | HF-2354 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | MYC,PCAT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_506 | hg19 | chr8:129573241-130968628 | chr8 | 129,573,241 | 130,968,628 | Disease | HF-2354 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_507 | hg19 | chr7:54929292-55441765 | chr7 | 54,929,292 | 55,441,765 | Disease | HF-2927 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_508 | hg19 | chr12:57603753-57621879 | chr12 | 57,603,753 | 57,621,879 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_509 | hg19 | chr12:57639418-58215685 | chr12 | 57,639,418 | 58,215,685 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | AGAP2,CDK4,DDIT3,GLI1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_510 | hg19 | chr7:54910016-55158745 | chr7 | 54,910,016 | 55,158,745 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_511 | hg19 | chr7:55189107-55235603 | chr7 | 55,189,107 | 55,235,603 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_512 | hg19 | chr7:55240808-55377598 | chr7 | 55,240,808 | 55,377,598 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_513 | hg19 | chr8:128216468-130393662 | chr8 | 128,216,468 | 130,393,662 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | MYC,PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_514 | hg19 | chr8:130401182-130405320 | chr8 | 130,401,182 | 130,405,320 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_515 | hg19 | chr8:130416078-130537190 | chr8 | 130,416,078 | 130,537,190 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_516 | hg19 | chr8:130560626-130693908 | chr8 | 130,560,626 | 130,693,908 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_517 | hg19 | chr8:130717776-131148654 | chr8 | 130,717,776 | 131,148,654 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_518 | hg19 | chr8:131172024-131187476 | chr8 | 131,172,024 | 131,187,476 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_519 | hg19 | chr8:131199169-131340108 | chr8 | 131,199,169 | 131,340,108 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_520 | hg19 | chr8:131348437-131365459 | chr8 | 131,348,437 | 131,365,459 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_521 | hg19 | chr8:131373255-131411104 | chr8 | 131,373,255 | 131,411,104 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_522 | hg19 | chr8:131443982-131892876 | chr8 | 131,443,982 | 131,892,876 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_523 | hg19 | chr8:135219161-135991091 | chr8 | 135,219,161 | 135,991,091 | Disease | HF-3016 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_524 | hg19 | chr12:57603753-57621879 | chr12 | 57,603,753 | 57,621,879 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_525 | hg19 | chr12:57749466-57797657 | chr12 | 57,749,466 | 57,797,657 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_526 | hg19 | chr12:57872514-57906516 | chr12 | 57,872,514 | 57,906,516 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_527 | hg19 | chr12:57914344-57964995 | chr12 | 57,914,344 | 57,964,995 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_528 | hg19 | chr12:58136186-58161608 | chr12 | 58,136,186 | 58,161,608 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | CDK4 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_529 | hg19 | chr12:58198004-58215685 | chr12 | 58,198,004 | 58,215,685 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_530 | hg19 | chr7:54910016-55158745 | chr7 | 54,910,016 | 55,158,745 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_531 | hg19 | chr7:55189107-55235603 | chr7 | 55,189,107 | 55,235,603 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_532 | hg19 | chr7:55240808-55377598 | chr7 | 55,240,808 | 55,377,598 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | EGFR | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_533 | hg19 | chr8:128216468-128494866 | chr8 | 128,216,468 | 128,494,866 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_534 | hg19 | chr8:128608023-128804027 | chr8 | 128,608,023 | 128,804,027 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | MYC | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_535 | hg19 | chr8:128821521-128901747 | chr8 | 128,821,521 | 128,901,747 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_536 | hg19 | chr8:128921637-128939392 | chr8 | 128,921,637 | 128,939,392 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_537 | hg19 | chr8:128966453-129030077 | chr8 | 128,966,453 | 129,030,077 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_538 | hg19 | chr8:129050386-129087164 | chr8 | 129,050,386 | 129,087,164 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_539 | hg19 | chr8:129138835-129275515 | chr8 | 129,138,835 | 129,275,515 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_540 | hg19 | chr8:129309690-129346561 | chr8 | 129,309,690 | 129,346,561 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_541 | hg19 | chr8:129771519-129813209 | chr8 | 129,771,519 | 129,813,209 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_542 | hg19 | chr8:129856581-129901946 | chr8 | 129,856,581 | 129,901,946 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_543 | hg19 | chr8:129950014-130369689 | chr8 | 129,950,014 | 130,369,689 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_544 | hg19 | chr8:130423550-130441106 | chr8 | 130,423,550 | 130,441,106 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_545 | hg19 | chr8:130664286-130694946 | chr8 | 130,664,286 | 130,694,946 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_546 | hg19 | chr8:130718851-130930542 | chr8 | 130,718,851 | 130,930,542 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_547 | hg19 | chr8:131048033-131148654 | chr8 | 131,048,033 | 131,148,654 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_548 | hg19 | chr8:131199169-131254686 | chr8 | 131,199,169 | 131,254,686 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_549 | hg19 | chr8:131262806-131287610 | chr8 | 131,262,806 | 131,287,610 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_550 | hg19 | chr8:131443982-131842476 | chr8 | 131,443,982 | 131,842,476 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_551 | hg19 | chr8:135219161-135246785 | chr8 | 135,219,161 | 135,246,785 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_552 | hg19 | chr8:135323700-135337092 | chr8 | 135,323,700 | 135,337,092 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_553 | hg19 | chr8:135345699-135372294 | chr8 | 135,345,699 | 135,372,294 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_554 | hg19 | chr8:135482680-135563156 | chr8 | 135,482,680 | 135,563,156 | Disease | HF-3177 | Glioblastoma | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | Not Available |
Homo sapiens | ecDNA | ec_hsa_555 | hg19 | chr8:112340001-112380000 | chr8 | 112,340,001 | 112,380,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_556 | hg19 | chr8:119550001-119740000 | chr8 | 119,550,001 | 119,740,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_557 | hg19 | chr8:119740001-119950000 | chr8 | 119,740,001 | 119,950,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_558 | hg19 | chr8:120060001-120130000 | chr8 | 120,060,001 | 120,130,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_559 | hg19 | chr8:122370001-122490000 | chr8 | 122,370,001 | 122,490,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_560 | hg19 | chr8:122860001-122970000 | chr8 | 122,860,001 | 122,970,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_561 | hg19 | chr8:124960001-125160000 | chr8 | 124,960,001 | 125,160,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_562 | hg19 | chr8:127320001-127580000 | chr8 | 127,320,001 | 127,580,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_563 | hg19 | chr8:127580001-127660000 | chr8 | 127,580,001 | 127,660,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_564 | hg19 | chr8:128730001-128850000 | chr8 | 128,730,001 | 128,850,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | MYC,PVT1 | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_565 | hg19 | chr8:129560001-129660000 | chr8 | 129,560,001 | 129,660,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_566 | hg19 | chr8:131460001-131710000 | chr8 | 131,460,001 | 131,710,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_567 | hg19 | chr8:131710001-131740000 | chr8 | 131,710,001 | 131,740,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_568 | hg19 | chr8:131740001-131880000 | chr8 | 131,740,001 | 131,880,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_569 | hg19 | chr8:133860001-133910000 | chr8 | 133,860,001 | 133,910,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_570 | hg19 | chr8:134670001-134790000 | chr8 | 134,670,001 | 134,790,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_571 | hg19 | chr8:134790001-134840000 | chr8 | 134,790,001 | 134,840,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_572 | hg19 | chr8:137580001-137660000 | chr8 | 137,580,001 | 137,660,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_573 | hg19 | chr8:137880001-138380000 | chr8 | 137,880,001 | 138,380,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_574 | hg19 | chr8:139250001-139350000 | chr8 | 139,250,001 | 139,350,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_575 | hg19 | chr8:139350001-139470000 | chr8 | 139,350,001 | 139,470,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_576 | hg19 | chr8:139470001-139560000 | chr8 | 139,470,001 | 139,560,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_577 | hg19 | chr8:140190001-140380000 | chr8 | 140,190,001 | 140,380,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_578 | hg19 | chr8:140600001-140650000 | chr8 | 140,600,001 | 140,650,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_579 | hg19 | chr8:142200001-142290000 | chr8 | 142,200,001 | 142,290,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_580 | hg19 | chr8:145210001-145600000 | chr8 | 145,210,001 | 145,600,000 | Disease | PC3 | Prostate Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | All data described in this study are being deposited in NCBI's Gene Expression Omnibus:GSE124769. Whole-genome sequencing data for PC3 ecDNA (+) and ecDNA (-) cell lines were obtained from SRA SRR4009277 and SRR5263237 | WGS | 33836152 | 2021 | 1.ecDNAs display widespread, genome-wide chromatin interactions;2.ecDNA-chromosomal contacts converge on non-coding regions with high H3K27ac signals;3.ecDNAs are enriched for enhancer signatures and are associated with transcriptionally active chromosomal genes;4.Perturbation of ecDNA identity and level resulted in the dysregulation of chromosomal gene transcription | From PC3 ecDNA (+) cancer cell line |
Homo sapiens | ecDNA | ec_hsa_581 | hg19 | chr1:695666-716261 | chr1 | 695,666 | 716,261 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:695666-716261,chr1:16411224-16411820,chr2:32991485-33241936,chr4:33823405-33864000,chr4:120350550-120391145,chr6:32476766-32517361,chr6:134831238-134851834,chr7:32982634-33053842,chr7:39886375-39926970,chr7:45787730-45812936,chr7:50661787-63116350,chr7:63167917-63168513,chr7:64444705-64675301,chr7:65217646-65388242,chr7:142771616-142792211,chr7:151690230-151690826,chr11:50236231-50256826,chr14:45515747-45516343,chr17:20771647-20792243,chr18:30221408-30222004,chr20:25741621-25782216,chrX:33532824-33533420,chrX:140309373-140329969 |
Homo sapiens | ecDNA | ec_hsa_582 | hg19 | chr1:1193163-1193631 | chr1 | 1,193,163 | 1,193,631 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:1193163-1193631,chr2:114246153-114446621,chr2:233917503-233917971,chr7:54632320-56104875,chr12:1-24689138,chr20:61458697-63025520 |
Homo sapiens | ecDNA | ec_hsa_583 | hg19 | chr1:1259208-1459727 | chr1 | 1,259,208 | 1,459,727 | Disease | Uterine Corpus Endometrial | Uterine Corpus Endometrial Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_584 | hg19 | chr1:2022154-2390081 | chr1 | 2,022,154 | 2,390,081 | Disease | Stomach | Gastric Cancer | Prediction | AmpliconArchitect | Not Available | SKI | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:2022154-2390081,chr8:13923395-14435566,chr8:80993467-82165402,chr15:86276720-86477108,chr15:90679258-91430475,chr18:45727851-46927242 |
Homo sapiens | ecDNA | ec_hsa_585 | hg19 | chr1:6027724-7159639 | chr1 | 6,027,724 | 7,159,639 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:6027724-7159639,chr1:192774533-192775106,chr2:33041296-33241868,chr12:108861917-108862490,chr19:32575508-32576081 |
Homo sapiens | ecDNA | ec_hsa_586 | hg19 | chr1:6772112-12619985 | chr1 | 6,772,112 | 12,619,985 | Disease | Pancreatic | Pancreatic Cancer | Prediction | AmpliconArchitect | Not Available | MTOR,PARK7,RERE,TNFRSF1B | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_587 | hg19 | chr1:7983900-8184324 | chr1 | 7,983,900 | 8,184,324 | Disease | Bladder | Bladder Cancer | Prediction | AmpliconArchitect | Not Available | PARK7 | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_588 | hg19 | chr1:8882186-10508136 | chr1 | 8,882,186 | 10,508,136 | Disease | Ovary | Ovarian Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_589 | hg19 | chr1:9049646-9260120 | chr1 | 9,049,646 | 9,260,120 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:9049646-9260120,chr1:10458973-11046928 |
Homo sapiens | ecDNA | ec_hsa_590 | hg19 | chr1:9958395-11333238 | chr1 | 9,958,395 | 11,333,238 | Disease | Stomach | Gastric Cancer | Prediction | AmpliconArchitect | Not Available | MTOR | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_591 | hg19 | chr1:10440297-11210278 | chr1 | 10,440,297 | 11,210,278 | Disease | Stomach | Gastric Cancer | Prediction | AmpliconArchitect | Not Available | MTOR | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_592 | hg19 | chr1:10458973-11046928 | chr1 | 10,458,973 | 11,046,928 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:9049646-9260120,chr1:10458973-11046928 |
Homo sapiens | ecDNA | ec_hsa_593 | hg19 | chr1:10670875-10671478 | chr1 | 10,670,875 | 10,671,478 | Disease | Skin | Skin Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:10670875-10671478,chr4:612083-812685,chr4:1235325-2399704,chr4:2421243-2639081,chr4:2804432-3041555,chr4:3139534-3371524,chr4:4730973-4751576,chr4:5125076-15921178,chr4:17211214-17411816,chr4:17624542-17825145,chr4:18106523-18127126,chr4:21770448-21971050,chr4:22090374-22400272,chr4:22621561-22822163,chr4:28708715-28769118,chr4:29081788-29082391,chr4:29474683-29679738,chr4:31929378-32250617,chr5:0-1471536,chr5:1644560-1857851,chr5:3207354-3416942,chr5:4602132-4706341,chr5:5434777-5654936,chr5:6946726-7193653,chr5:7211316-9665894,chr5:11299991-11394190,chr5:11539638-11575454,chr5:12048380-12412964,chr5:12543715-12544318,chr5:12950628-16359352,chr5:17787426-17993134,chr5:18017459-18253571,chr5:19125556-20587415,chr5:27519678-27800007,chr5:30322291-30757281,chr5:35427012-38390396,chrY:13215914-13976517,chrY:23519418-23520021,chrY:23535850-23536453,chrY:24885985-24906587,chrY:24919741-24940343,chrY:26519738-26540340,chrY:27067934-27068537,chrY:27422053-27422656,chrY:28684309-28924912,chrY:58706213-59156854 |
Homo sapiens | ecDNA | ec_hsa_594 | hg19 | chr1:10870892-10881609 | chr1 | 10,870,892 | 10,881,609 | Disease | Stomach | Gastric Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:10870892-10881609 |
Homo sapiens | ecDNA | ec_hsa_595 | hg19 | chr1:11362379-11362906 | chr1 | 11,362,379 | 11,362,906 | Disease | Lung | Lung Adenocarcinoma | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_596 | hg19 | chr1:11436535-11952212 | chr1 | 11,436,535 | 11,952,212 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:11436535-11952212,chr1:11957767-11958351 |
Homo sapiens | ecDNA | ec_hsa_597 | hg19 | chr1:11886955-11887509 | chr1 | 11,886,955 | 11,887,509 | Disease | Bladder | Bladder Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:11886955-11887509,chr3:10070994-10111547,chr3:11085602-13193994,chr3:45356162-46726716,chr3:47835932-47836486,chr3:147526586-147547140,chr4:116567328-116567882,chr5:51072638-51073192,chr5:124951456-124972010,chr6:17707310-17727863,chr6:123336639-123357193,chr7:79408403-79408957,chr8:4301272-4301826,chr8:61258072-61258626,chr8:96139845-96140399,chr9:82099966-82100520,chr11:1601205-1601759,chr13:36817074-36817628,chr17:6414753-6415307,chr17:9735271-9735825,chr18:19596362-19596916,chr18:67911272-67911826,chrX:102445885-102446439,chrX:132350829-133784891 |
Homo sapiens | ecDNA | ec_hsa_598 | hg19 | chr1:11957767-11958351 | chr1 | 11,957,767 | 11,958,351 | Disease | Esophagus | Esophageal Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | These chromosome segments together form the ecDNA:chr1:11436535-11952212,chr1:11957767-11958351 |
Homo sapiens | ecDNA | ec_hsa_599 | hg19 | chr1:13525425-13546065 | chr1 | 13,525,425 | 13,546,065 | Disease | Ovary | Ovarian Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |
Homo sapiens | ecDNA | ec_hsa_600 | hg19 | chr1:13724100-14321304 | chr1 | 13,724,100 | 14,321,304 | Disease | Ovary | Ovarian Cancer | Prediction | AmpliconArchitect | Not Available | Not Available | Information on accessing the data from the International Cancer Genomics Consortium, including raw read files, can be found at https://docs.icgc.org/pcawg/data/. All open-access TCGA data are publicly available through NCI Genomic Data Commons (https://gdc.cancer.gov/). | WGS | 32807987 | 2021 | EcDNA amplifications resulted in higher levels of oncogene transcription compared to copy number-matched linear DNA, coupled with enhanced chromatin accessibility, and more frequently resulted in transcript fusions. | Not Available |