sentence1: Changes in miR-146a and miR-146b expression and/or binding have also been implicated in the metastatic and proliferative response associated with the development of papillary thyroid carcinoma (PTC) and cervical cancer, ovarian cancer, breast cancer and pancreatic cancer and prostate cancer.
sentence2: Additionally, loss of LATS2 stimulated reduplication, an activity comparable to that observed when Cyclin E is overexpressed in the absence of p53