Update README.md

README.md

@@ -9,335 +9,398 @@ tags:
 - dataset_size:26147930
 - loss:MultipleNegativesRankingLoss
 widget:
-- source_sentence: '[YEAR_RANGE] 2020-2024 [TEXT] Vitamin B-6 Prevents Heart Failure
-    with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model.'
+- source_sentence: >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Vitamin B-6 Prevents Heart Failure with
+    Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model.
   sentences:
-  - '[YEAR_RANGE] 2020-2024 [TEXT] Colorectal cancer (CRC) is a complex and genetically
-    heterogeneous disease presenting a specific metastatic pattern, with the liver
-    being the most common site of metastasis. Around 20%-25% of patients with CRC
-    will develop exclusively hepatic metastatic disease throughout their disease history.
-    With its specific characteristics and therapeutic options, liver-limited disease
-    (LLD) should be considered as a specific entity. The identification of these patients
-    is particularly relevant in view of the growing interest in liver transplantation
-    in selected patients with advanced CRC. Identifying why some patients will develop
-    only LLD remains a challenge, mainly because of a lack of a systemic understanding
-    of this complex and interlinked phenomenon given that cancer has traditionally
-    been investigated according to distinct physiological compartments. Recently,
-    multidisciplinary efforts and new diagnostic tools have made it possible to study
-    some of these complex issues in greater depth and may help identify targets and
-    specific treatment strategies to benefit these patients. In this review we analyze
-    the underlying biology and available tools to help clinicians better understand
-    this increasingly common and specific disease.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] PURPOSE: Secondary breast cancer is a frequent
-    late adverse event of mediastinal Hodgkin lymphoma radiotherapy. Secondary breast
-    cancers overwhelmingly correspond to ductal carcinoma and develop from the glandular
-    mammary tissue. In addition, during childhood, radiation overexposure of the glandular
-    tissue may lead to a late breast hypotrophy at adult age. The aim of this study
-    was to evaluate the radiation exposure to the glandular tissue in patients treated
-    for mediastinal Hodgkin lymphoma with intensity-modulated proton therapy, in order
-    to evaluate the potential dosimetric usefulness of its delineation for breast
-    sparing. MATERIALS AND METHODS: Sixteen consecutive intermediate-risk mediastinal
-    female patients with Hodgkin lymphoma treated with consolidation radiation with
-    deep inspiration breath hold intensity-modulated proton therapy to the total dose
-    of 30Gy were included. Breasts were delineated according to the European Society
-    for Radiotherapy and Oncology guidelines for treatment optimization ("clinical
-    organ at risk"). The glandular tissue ("glandular organ at risk") was retrospectively
-    contoured on the initial simulation CT scans based on Hounsfield unit (HU) values,
-    using a range between -80HU and 500HU. RESULTS: The mean and maximum doses delivered
-    to the glandular organ at risk were significantly lower than the mean and maximum
-    doses delivered to the clinical organ at risk, but were statistically correlated.
-    Glandular organ at risk volumes were significantly smaller. CONCLUSION: Optimizing
-    the treatment plans on the clinical breast contours will systematically lead to
-    overestimation of the dose received to the glandular tissue and, consequently,
-    to an indistinct and involuntary improved glandular tissue sparing. As such, our
-    findings do not support the consideration of the glandular tissue as an additional
-    organ at risk when planning intensity-modulated proton therapy for mediastinal
-    Hodgkin lymphoma in female patients.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] BACKGROUND: There is an urgent need to develop
-    an efficient therapeutic strategy for heart failure with preserved ejection fraction
-    (HFpEF), which is mediated by phenotypic changes in cardiac macrophages. We previously
-    reported that vitamin B-6 inhibits macrophage-mediated inflammasome activation.
-    OBJECTIVES: We sought to examine whether the prophylactic use of vitamin B-6 prevents
-    HFpEF. METHODS: HFpEF model was elicited by a combination of high-fat diet and
-    Nω-nitro-l-arginine methyl ester supplement in mice. Cardiac function was assessed
-    using conventional echocardiography and Doppler imaging. Immunohistochemistry
-    and immunoblotting were used to detect changes in the macrophage phenotype and
-    myocardial remodeling-related molecules. RESULTS: Co-administration of vitamin
-    B-6 with HFpEF mice mitigated HFpEF phenotypes, including diastolic dysfunction,
-    cardiac macrophage phenotypic shifts, fibrosis, and hypertrophy. Echocardiographic
-    improvements were observed, with the E/E'' ratio decreasing from 42.0 to 21.6
-    and the E/A ratio improving from 2.13 to 1.17. The exercise capacity also increased
-    from 295.3 to 657.7 min. However, these beneficial effects were negated in downstream
-    of kinase (DOK) 3-deficient mice. Mechanistically, vitamin B-6 increased DOK3
-    protein concentrations and inhibited macrophage phenotypic changes, which were
-    abrogated by an AMP-activated protein kinase inhibitor. CONCLUSIONS: Vitamin B-6
-    increases DOK3 signaling to lower risk of HFpEF by inhibiting phenotypic changes
-    in cardiac macrophages.'
-- source_sentence: '[YEAR_RANGE] 2020-2024 [TEXT] Resolving phylogenetic relationships
-    and taxonomic revision in the Pseudogastromyzon (Cypriniformes, Gastromyzonidae)
-    genus: molecular and morphological evidence for a new genus, Labigastromyzon.'
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Colorectal cancer (CRC) is a complex and
+    genetically heterogeneous disease presenting a specific metastatic pattern,
+    with the liver being the most common site of metastasis. Around 20%-25% of
+    patients with CRC will develop exclusively hepatic metastatic disease
+    throughout their disease history. With its specific characteristics and
+    therapeutic options, liver-limited disease (LLD) should be considered as a
+    specific entity. The identification of these patients is particularly
+    relevant in view of the growing interest in liver transplantation in
+    selected patients with advanced CRC. Identifying why some patients will
+    develop only LLD remains a challenge, mainly because of a lack of a systemic
+    understanding of this complex and interlinked phenomenon given that cancer
+    has traditionally been investigated according to distinct physiological
+    compartments. Recently, multidisciplinary efforts and new diagnostic tools
+    have made it possible to study some of these complex issues in greater depth
+    and may help identify targets and specific treatment strategies to benefit
+    these patients. In this review we analyze the underlying biology and
+    available tools to help clinicians better understand this increasingly
+    common and specific disease.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] PURPOSE: Secondary breast cancer is a frequent
+    late adverse event of mediastinal Hodgkin lymphoma radiotherapy. Secondary
+    breast cancers overwhelmingly correspond to ductal carcinoma and develop
+    from the glandular mammary tissue. In addition, during childhood, radiation
+    overexposure of the glandular tissue may lead to a late breast hypotrophy at
+    adult age. The aim of this study was to evaluate the radiation exposure to
+    the glandular tissue in patients treated for mediastinal Hodgkin lymphoma
+    with intensity-modulated proton therapy, in order to evaluate the potential
+    dosimetric usefulness of its delineation for breast sparing. MATERIALS AND
+    METHODS: Sixteen consecutive intermediate-risk mediastinal female patients
+    with Hodgkin lymphoma treated with consolidation radiation with deep
+    inspiration breath hold intensity-modulated proton therapy to the total dose
+    of 30Gy were included. Breasts were delineated according to the European
+    Society for Radiotherapy and Oncology guidelines for treatment optimization
+    ("clinical organ at risk"). The glandular tissue ("glandular organ at risk")
+    was retrospectively contoured on the initial simulation CT scans based on
+    Hounsfield unit (HU) values, using a range between -80HU and 500HU. RESULTS:
+    The mean and maximum doses delivered to the glandular organ at risk were
+    significantly lower than the mean and maximum doses delivered to the
+    clinical organ at risk, but were statistically correlated. Glandular organ
+    at risk volumes were significantly smaller. CONCLUSION: Optimizing the
+    treatment plans on the clinical breast contours will systematically lead to
+    overestimation of the dose received to the glandular tissue and,
+    consequently, to an indistinct and involuntary improved glandular tissue
+    sparing. As such, our findings do not support the consideration of the
+    glandular tissue as an additional organ at risk when planning
+    intensity-modulated proton therapy for mediastinal Hodgkin lymphoma in
+    female patients.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] BACKGROUND: There is an urgent need to develop
+    an efficient therapeutic strategy for heart failure with preserved ejection
+    fraction (HFpEF), which is mediated by phenotypic changes in cardiac
+    macrophages. We previously reported that vitamin B-6 inhibits
+    macrophage-mediated inflammasome activation. OBJECTIVES: We sought to
+    examine whether the prophylactic use of vitamin B-6 prevents HFpEF. METHODS:
+    HFpEF model was elicited by a combination of high-fat diet and
+    Nω-nitro-l-arginine methyl ester supplement in mice. Cardiac function was
+    assessed using conventional echocardiography and Doppler imaging.
+    Immunohistochemistry and immunoblotting were used to detect changes in the
+    macrophage phenotype and myocardial remodeling-related molecules. RESULTS:
+    Co-administration of vitamin B-6 with HFpEF mice mitigated HFpEF phenotypes,
+    including diastolic dysfunction, cardiac macrophage phenotypic shifts,
+    fibrosis, and hypertrophy. Echocardiographic improvements were observed,
+    with the E/E' ratio decreasing from 42.0 to 21.6 and the E/A ratio improving
+    from 2.13 to 1.17. The exercise capacity also increased from 295.3 to 657.7
+    min. However, these beneficial effects were negated in downstream of kinase
+    (DOK) 3-deficient mice. Mechanistically, vitamin B-6 increased DOK3 protein
+    concentrations and inhibited macrophage phenotypic changes, which were
+    abrogated by an AMP-activated protein kinase inhibitor. CONCLUSIONS: Vitamin
+    B-6 increases DOK3 signaling to lower risk of HFpEF by inhibiting phenotypic
+    changes in cardiac macrophages.
+- source_sentence: >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Resolving phylogenetic relationships and
+    taxonomic revision in the Pseudogastromyzon (Cypriniformes, Gastromyzonidae)
+    genus: molecular and morphological evidence for a new genus,
+    Labigastromyzon.
   sentences:
-  - '[YEAR_RANGE] 2020-2024 [TEXT] Bats contain a diverse spectrum of viral species
-    in their bodies. The RNA virus family Paramyxoviridae tends to infect several
-    vertebrate species, which are accountable for a variety of devastating infections
-    in both humans and animals. Viruses of this kind include measles, mumps, and Hendra.
-    Some synonymous codons are favoured over others in mRNAs during gene-to-protein
-    synthesis process. Such phenomenon is termed as codon usage bias (CUB). Our research
-    emphasized many aspects that shape the CUB of genes in the Paramyxoviridae family
-    found in bats. Here, the nitrogenous base A occurred the most. AT was found to
-    be abundant in the coding sequences of the Paramyxoviridae family. RSCU data revealed
-    that A or T ending codons occurred more frequently than predicted. Furthermore,
-    3 overrepresented codons (CAT, AGA, and GCA) and 7 underrepresented codons (CCG,
-    TCG, CGC, CGG, CGT, GCG and ACG) were detected in the viral genomes. Correspondence
-    analysis, neutrality plot, and parity plots highlight the combined impact of mutational
-    pressure and natural selection on CUB. The neutrality plot of GC12 against GC3
-    yielded a regression coefficient value of 0.366, indicating that natural selection
-    had a significant (63.4 %) impact. Moreover, RNA editing analysis was done, which
-    revealed the highest frequency of C to T mutations. The results of our research
-    revealed the pattern of codon usage and RNA editing sites in Paramyxoviridae genomes.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: The preoperative inclination angle of
-    mandibular incisors was crucial for surgical and postoperative stability while
-    the effect of proclined mandibular incisors on skeletal stability has not been
-    investigated. This study aimed to evaluate the effects of differences in presurgical
-    mandibular incisor inclination on skeletal stability after orthognathic surgery
-    in patients with skeletal Class III malocclusion. METHODS: A retrospective cohort
-    study of 80 consecutive patients with skeletal Class III malocclusion who underwent
-    bimaxillary orthognathic surgery was conducted. According to incisor mandibular
-    plane angle (IMPA), patients were divided into 3 groups: retroclined inclination
-    (IMPA < 87°), normal inclination (87° ≤ IMPA < 93°) and proclined inclination
-    (IMPA ≥ 93°). Preoperative characteristics, surgical changes and postoperative
-    stability were compared based on lateral cephalograms obtained 1 week before surgery
-    (T0), 1 week after surgery (T1), and at 6 to 12 months postoperatively (T2). RESULTS:
-    The mandible demonstrated a forward and upward relapse in all three groups. No
-    significant differences in skeletal relapse were observed in the 3 groups of patients.
-    However, the proclined inclination group showed a negative overbite tendency postoperatively
-    compared with the other two groups and a clinically significant mandibular relapse
-    pattern. Proclined IMPA both pre- and postoperatively was correlated with mandibular
-    relapse. CONCLUSION: Sufficient presurgical mandibular incisor decompensation
-    was of crucial importance for the maintenance of skeletal stability in patients
-    with skeletal Class III malocclusion who subsequently underwent orthognathic surgery.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] The Pseudogastromyzon genus, consisting of species
-    predominantly distributed throughout southeastern China, has garnered increasing
-    market attention in recent years due to its ornamental appeal. However, the overlapping
-    diagnostic attributes render the commonly accepted criteria for interspecific
-    identification unreliable, leaving the phylogenetic relationships among Pseudogastromyzon
-    species unexplored. In the present study, we undertake molecular phylogenetic
-    and morphological examinations of the Pseudogastromyzon genus. Our phylogenetic
-    analysis of mitochondrial genes distinctly segregated Pseudogastromyzon species
-    into two clades: the Pseudogastromyzon clade and the Labigastromyzon clade. A
-    subsequent morphological assessment revealed that the primary dermal ridge (specifically,
-    the second ridge) within the labial adhesive apparatus serves as an effective
-    and precise interspecific diagnostic characteristic. Moreover, the distributional
-    ranges of Pseudogastromyzon and Labigastromyzon are markedly distinct, exhibiting
-    only a narrow area of overlap. Considering the morphological heterogeneity of
-    the labial adhesive apparatus and the substantial division within the molecular
-    phylogeny, we advocate for the elevation of the Labigastromyzon subgenus to the
-    status of a separate genus. Consequently, we have ascertained the validity of
-    the Pseudogastromyzon and Labigastromyzon species, yielding a total of six valid
-    species. To facilitate future research, we present comprehensive descriptions
-    of the redefined species and introduce novel identification keys.'
-- source_sentence: '[YEAR_RANGE] 2020-2024 [TEXT] PCa-RadHop: A transparent and lightweight
-    feed-forward method for clinically significant prostate cancer segmentation.'
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Bats contain a diverse spectrum of viral
+    species in their bodies. The RNA virus family Paramyxoviridae tends to
+    infect several vertebrate species, which are accountable for a variety of
+    devastating infections in both humans and animals. Viruses of this kind
+    include measles, mumps, and Hendra. Some synonymous codons are favoured over
+    others in mRNAs during gene-to-protein synthesis process. Such phenomenon is
+    termed as codon usage bias (CUB). Our research emphasized many aspects that
+    shape the CUB of genes in the Paramyxoviridae family found in bats. Here,
+    the nitrogenous base A occurred the most. AT was found to be abundant in the
+    coding sequences of the Paramyxoviridae family. RSCU data revealed that A or
+    T ending codons occurred more frequently than predicted. Furthermore, 3
+    overrepresented codons (CAT, AGA, and GCA) and 7 underrepresented codons
+    (CCG, TCG, CGC, CGG, CGT, GCG and ACG) were detected in the viral genomes.
+    Correspondence analysis, neutrality plot, and parity plots highlight the
+    combined impact of mutational pressure and natural selection on CUB. The
+    neutrality plot of GC12 against GC3 yielded a regression coefficient value
+    of 0.366, indicating that natural selection had a significant (63.4 %)
+    impact. Moreover, RNA editing analysis was done, which revealed the highest
+    frequency of C to T mutations. The results of our research revealed the
+    pattern of codon usage and RNA editing sites in Paramyxoviridae genomes.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: The preoperative inclination angle
+    of mandibular incisors was crucial for surgical and postoperative stability
+    while the effect of proclined mandibular incisors on skeletal stability has
+    not been investigated. This study aimed to evaluate the effects of
+    differences in presurgical mandibular incisor inclination on skeletal
+    stability after orthognathic surgery in patients with skeletal Class III
+    malocclusion. METHODS: A retrospective cohort study of 80 consecutive
+    patients with skeletal Class III malocclusion who underwent bimaxillary
+    orthognathic surgery was conducted. According to incisor mandibular plane
+    angle (IMPA), patients were divided into 3 groups: retroclined inclination
+    (IMPA < 87°), normal inclination (87° ≤ IMPA < 93°) and proclined
+    inclination (IMPA ≥ 93°). Preoperative characteristics, surgical changes and
+    postoperative stability were compared based on lateral cephalograms obtained
+    1 week before surgery (T0), 1 week after surgery (T1), and at 6 to 12 months
+    postoperatively (T2). RESULTS: The mandible demonstrated a forward and
+    upward relapse in all three groups. No significant differences in skeletal
+    relapse were observed in the 3 groups of patients. However, the proclined
+    inclination group showed a negative overbite tendency postoperatively
+    compared with the other two groups and a clinically significant mandibular
+    relapse pattern. Proclined IMPA both pre- and postoperatively was correlated
+    with mandibular relapse. CONCLUSION: Sufficient presurgical mandibular
+    incisor decompensation was of crucial importance for the maintenance of
+    skeletal stability in patients with skeletal Class III malocclusion who
+    subsequently underwent orthognathic surgery.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] The Pseudogastromyzon genus, consisting of
+    species predominantly distributed throughout southeastern China, has
+    garnered increasing market attention in recent years due to its ornamental
+    appeal. However, the overlapping diagnostic attributes render the commonly
+    accepted criteria for interspecific identification unreliable, leaving the
+    phylogenetic relationships among Pseudogastromyzon species unexplored. In
+    the present study, we undertake molecular phylogenetic and morphological
+    examinations of the Pseudogastromyzon genus. Our phylogenetic analysis of
+    mitochondrial genes distinctly segregated Pseudogastromyzon species into two
+    clades: the Pseudogastromyzon clade and the Labigastromyzon clade. A
+    subsequent morphological assessment revealed that the primary dermal ridge
+    (specifically, the second ridge) within the labial adhesive apparatus serves
+    as an effective and precise interspecific diagnostic characteristic.
+    Moreover, the distributional ranges of Pseudogastromyzon and Labigastromyzon
+    are markedly distinct, exhibiting only a narrow area of overlap. Considering
+    the morphological heterogeneity of the labial adhesive apparatus and the
+    substantial division within the molecular phylogeny, we advocate for the
+    elevation of the Labigastromyzon subgenus to the status of a separate genus.
+    Consequently, we have ascertained the validity of the Pseudogastromyzon and
+    Labigastromyzon species, yielding a total of six valid species. To
+    facilitate future research, we present comprehensive descriptions of the
+    redefined species and introduce novel identification keys.
+- source_sentence: >-
+    [YEAR_RANGE] 2020-2024 [TEXT] PCa-RadHop: A transparent and lightweight
+    feed-forward method for clinically significant prostate cancer segmentation.
   sentences:
-  - '[YEAR_RANGE] 2020-2024 [TEXT] According to the importance of time in treatment
-    of thrombosis disorders, faster than current treatments are required. For the
-    first time, this research discloses a novel strategy for rapid dissolution of
-    blood clots by encapsulation of a fibrinolytic (Reteplase) into a Thrombin sensitive
-    shell formed by polymerization of acrylamide monomers and bisacryloylated peptide
-    as crosslinker. Degradability of the peptide units in exposure to Thrombin, creates
-    the Thrombin-sensitive Reteplase nanocapsules (TSRNPs) as a triggered release
-    system. Accelerated thrombolysis was achieved by combining three approaches including:
-    deep penetration of TSRNPs into the blood clots, changing the clot dissolution
-    mechanism by altering the distribution pattern of TSRNPs to 3D intra-clot distribution
-    (based on the distributed intra-clot thrombolysis (DIT) model) instead of peripheral
-    and unidirectional distribution of unencapsulated fibrinolytics and, enzyme-stimulated
-    release of the fibrinolytic. Ex-vivo study was carried out by an occluded tube
-    model that mimics in-vivo brain stroke as an emergency situation where faster
-    treatment in short time is a golden key. In in vivo, efficacy of the developed
-    formulation was confirmed by PET scan and laser Doppler flowmetry (LDF). As the
-    most important achievements, 40.0 ± 0.7 (n = 3) % and 37.0 ± 0.4 (n = 3) % reduction
-    in the thrombolysis time (faster reperfusion) were observed by ex-vivo and in-vivo
-    experiments, respectively. Higher blood flow and larger digestion mass of clot
-    at similar times in comparison to non-encapsulated Reteplase were observed that
-    means more effective thrombolysis by the developed strategy.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] Prostate Cancer is one of the most frequently occurring
-    cancers in men, with a low survival rate if not early diagnosed. PI-RADS reading
-    has a high false positive rate, thus increasing the diagnostic incurred costs
-    and patient discomfort. Deep learning (DL) models achieve a high segmentation
-    performance, although require a large model size and complexity. Also, DL models
-    lack of feature interpretability and are perceived as "black-boxes" in the medical
-    field. PCa-RadHop pipeline is proposed in this work, aiming to provide a more
-    transparent feature extraction process using a linear model. It adopts the recently
-    introduced Green Learning (GL) paradigm, which offers a small model size and low
-    complexity. PCa-RadHop consists of two stages: Stage-1 extracts data-driven radiomics
-    features from the bi-parametric Magnetic Resonance Imaging (bp-MRI) input and
-    predicts an initial heatmap. To reduce the false positive rate, a subsequent stage-2
-    is introduced to refine the predictions by including more contextual information
-    and radiomics features from each already detected Region of Interest (ROI). Experiments
-    on the largest publicly available dataset, PI-CAI, show a competitive performance
-    standing of the proposed method among other deep DL models, achieving an area
-    under the curve (AUC) of 0.807 among a cohort of 1,000 patients. Moreover, PCa-RadHop
-    maintains orders of magnitude smaller model size and complexity.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: To evaluate rates of remission, recovery,
-    relapse, and recurrence in suicidal youth who participated in a clinical trial
-    comparing Dialectical Behavior Therapy (DBT) and Individual and Group Supportive
-    Therapy (IGST). METHOD: Participants were 173 youth, aged 12 to 18 years, with
-    repetitive self-harm (including at least 1 prior suicide attempt [SA]) and elevated
-    suicidal ideation (SI). Participants received 6 months of DBT or IGST and were
-    followed for 6 months post-treatment. The sample was 95% female, 56.4% White,
-    and 27.49% Latina. Remission was defined as absence of SA or nonsuicidal self-injury
-    (NSSI) across one 3-month interval; recovery was defined across 2 or more consecutive
-    intervals. Relapse and recurrence were defined as SA or NSSI following remission
-    or recovery. Cross-tabulation with χ2 was used for between-group contrasts. RESULTS:
-    Over 70% of the sample reported remission of SA at each treatment and follow-up
-    interval. There were significantly higher rates of remission and recovery and
-    lower rates of relapse and recurrence for SA in DBT than for IGST. Across treatments
-    and time points, SA had higher remission and recovery rates and lower relapse
-    and recurrence rates than NSSI. There were no significant differences in NSSI
-    remission between conditions; however, participants receiving DBT had significantly
-    higher NSSI recovery rates than those receiving IGST for the 3- to 9-month, 3-
-    to 12-month, and 6- to 12-month intervals. CONCLUSION: Results showed higher percentages
-    of SA remission and recovery for DBT as compared to IGST. NSSI was less likely
-    to remit than SA. PLAIN LANGUAGE SUMMARY: This study examined rates of remission,
-    recovery, relapse, and recurrence of suicide attempts (SA) and nonsuicidal self-injury
-    (NSSI) among the participants in the CARES Study, a randomized clinical trial
-    of 6 months of Dialectical Behavior Therapy or Individual and Group Supportive
-    Therapy. 173 youth aged 12 to 18 years participated in the study and were followed
-    for 6 months post treatment. Over 70% of the sample reported remission of SA at
-    each treatment and follow-up interval. There were significantly higher rates of
-    remission and recovery and lower rates of relapse and recurrence for SA among
-    participants who received Dialectical Behavioral Therapy. Across both treatments,
-    remission and recovery rates were lower and relapse and recurrence rates were
-    higher for NSSI than for SA. These results underscore the value of Dialectical
-    Behavioral Therapy as a first line treatment for youth at high risk for suicide.
-    DIVERSITY & INCLUSION STATEMENT: We worked to ensure race, ethnic, and/or other
-    types of diversity in the recruitment of human participants. CLINICAL TRIAL REGISTRATION
-    INFORMATION: Collaborative Adolescent Research on Emotions and Suicide (CARES);
-    https://www. CLINICALTRIALS: gov/; NCT01528020.'
-- source_sentence: '[YEAR_RANGE] 2020-2024 [TEXT] Predicting Recovery After Concussion
-    in Pediatric Patients: A Meta-Analysis.'
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] According to the importance of time in
+    treatment of thrombosis disorders, faster than current treatments are
+    required. For the first time, this research discloses a novel strategy for
+    rapid dissolution of blood clots by encapsulation of a fibrinolytic
+    (Reteplase) into a Thrombin sensitive shell formed by polymerization of
+    acrylamide monomers and bisacryloylated peptide as crosslinker.
+    Degradability of the peptide units in exposure to Thrombin, creates the
+    Thrombin-sensitive Reteplase nanocapsules (TSRNPs) as a triggered release
+    system. Accelerated thrombolysis was achieved by combining three approaches
+    including: deep penetration of TSRNPs into the blood clots, changing the
+    clot dissolution mechanism by altering the distribution pattern of TSRNPs to
+    3D intra-clot distribution (based on the distributed intra-clot thrombolysis
+    (DIT) model) instead of peripheral and unidirectional distribution of
+    unencapsulated fibrinolytics and, enzyme-stimulated release of the
+    fibrinolytic. Ex-vivo study was carried out by an occluded tube model that
+    mimics in-vivo brain stroke as an emergency situation where faster treatment
+    in short time is a golden key. In in vivo, efficacy of the developed
+    formulation was confirmed by PET scan and laser Doppler flowmetry (LDF). As
+    the most important achievements, 40.0 ± 0.7 (n = 3) % and 37.0 ± 0.4 (n = 3)
+    % reduction in the thrombolysis time (faster reperfusion) were observed by
+    ex-vivo and in-vivo experiments, respectively. Higher blood flow and larger
+    digestion mass of clot at similar times in comparison to non-encapsulated
+    Reteplase were observed that means more effective thrombolysis by the
+    developed strategy.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Prostate Cancer is one of the most frequently
+    occurring cancers in men, with a low survival rate if not early diagnosed.
+    PI-RADS reading has a high false positive rate, thus increasing the
+    diagnostic incurred costs and patient discomfort. Deep learning (DL) models
+    achieve a high segmentation performance, although require a large model size
+    and complexity. Also, DL models lack of feature interpretability and are
+    perceived as "black-boxes" in the medical field. PCa-RadHop pipeline is
+    proposed in this work, aiming to provide a more transparent feature
+    extraction process using a linear model. It adopts the recently introduced
+    Green Learning (GL) paradigm, which offers a small model size and low
+    complexity. PCa-RadHop consists of two stages: Stage-1 extracts data-driven
+    radiomics features from the bi-parametric Magnetic Resonance Imaging
+    (bp-MRI) input and predicts an initial heatmap. To reduce the false positive
+    rate, a subsequent stage-2 is introduced to refine the predictions by
+    including more contextual information and radiomics features from each
+    already detected Region of Interest (ROI). Experiments on the largest
+    publicly available dataset, PI-CAI, show a competitive performance standing
+    of the proposed method among other deep DL models, achieving an area under
+    the curve (AUC) of 0.807 among a cohort of 1,000 patients. Moreover,
+    PCa-RadHop maintains orders of magnitude smaller model size and complexity.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: To evaluate rates of remission,
+    recovery, relapse, and recurrence in suicidal youth who participated in a
+    clinical trial comparing Dialectical Behavior Therapy (DBT) and Individual
+    and Group Supportive Therapy (IGST). METHOD: Participants were 173 youth,
+    aged 12 to 18 years, with repetitive self-harm (including at least 1 prior
+    suicide attempt [SA]) and elevated suicidal ideation (SI). Participants
+    received 6 months of DBT or IGST and were followed for 6 months
+    post-treatment. The sample was 95% female, 56.4% White, and 27.49% Latina.
+    Remission was defined as absence of SA or nonsuicidal self-injury (NSSI)
+    across one 3-month interval; recovery was defined across 2 or more
+    consecutive intervals. Relapse and recurrence were defined as SA or NSSI
+    following remission or recovery. Cross-tabulation with χ2 was used for
+    between-group contrasts. RESULTS: Over 70% of the sample reported remission
+    of SA at each treatment and follow-up interval. There were significantly
+    higher rates of remission and recovery and lower rates of relapse and
+    recurrence for SA in DBT than for IGST. Across treatments and time points,
+    SA had higher remission and recovery rates and lower relapse and recurrence
+    rates than NSSI. There were no significant differences in NSSI remission
+    between conditions; however, participants receiving DBT had significantly
+    higher NSSI recovery rates than those receiving IGST for the 3- to 9-month,
+    3- to 12-month, and 6- to 12-month intervals. CONCLUSION: Results showed
+    higher percentages of SA remission and recovery for DBT as compared to IGST.
+    NSSI was less likely to remit than SA. PLAIN LANGUAGE SUMMARY: This study
+    examined rates of remission, recovery, relapse, and recurrence of suicide
+    attempts (SA) and nonsuicidal self-injury (NSSI) among the participants in
+    the CARES Study, a randomized clinical trial of 6 months of Dialectical
+    Behavior Therapy or Individual and Group Supportive Therapy. 173 youth aged
+    12 to 18 years participated in the study and were followed for 6 months post
+    treatment. Over 70% of the sample reported remission of SA at each treatment
+    and follow-up interval. There were significantly higher rates of remission
+    and recovery and lower rates of relapse and recurrence for SA among
+    participants who received Dialectical Behavioral Therapy. Across both
+    treatments, remission and recovery rates were lower and relapse and
+    recurrence rates were higher for NSSI than for SA. These results underscore
+    the value of Dialectical Behavioral Therapy as a first line treatment for
+    youth at high risk for suicide. DIVERSITY & INCLUSION STATEMENT: We worked
+    to ensure race, ethnic, and/or other types of diversity in the recruitment
+    of human participants. CLINICAL TRIAL REGISTRATION INFORMATION:
+    Collaborative Adolescent Research on Emotions and Suicide (CARES);
+    https://www. CLINICALTRIALS: gov/; NCT01528020.
+- source_sentence: >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Predicting Recovery After Concussion in
+    Pediatric Patients: A Meta-Analysis.
   sentences:
-  - '[YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: The authors examined licensing requirements
-    for select children''s behavioral health care providers. METHODS: Statutes and
-    regulations as of October 2021 were reviewed for licensed clinical social workers,
-    licensed professional counselors, and licensed marriage and family therapists
-    for all 50 U.S. states and the District of Columbia. RESULTS: All jurisdictions
-    had laws regarding postgraduate training and license portability. No jurisdiction
-    included language about specialized postgraduate training related to serving children
-    and families or cultural competence. Other policies that related to the structure,
-    composition, and authority of licensing boards varied across states and licensure
-    types. CONCLUSIONS: In their efforts to address barriers to licensure, expand
-    the workforce, and ensure that children have access to high-quality and culturally
-    responsive care, states could consider their statutes and regulations.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] Magnetic Resonance Imaging (MRI) plays a pivotal
-    role in the accurate measurement of brain subcortical structures in macaques,
-    which is crucial for unraveling the complexities of brain structure and function,
-    thereby enhancing our understanding of neurodegenerative diseases and brain development.
-    However, due to significant differences in brain size, structure, and imaging
-    characteristics between humans and macaques, computational tools developed for
-    human neuroimaging studies often encounter obstacles when applied to macaques.
-    In this context, we propose an Anatomy Attentional Fusion Network (AAF-Net), which
-    integrates multimodal MRI data with anatomical constraints in a multi-scale framework
-    to address the challenges posed by the dynamic development, regional heterogeneity,
-    and age-related size variations of the juvenile macaque brain, thus achieving
-    precise subcortical segmentation. Specifically, we generate a Signed Distance
-    Map (SDM) based on the initial rough segmentation of the subcortical region by
-    a network as an anatomical constraint, providing comprehensive information on
-    positions, structures, and morphology. Then we construct AAF-Net to fully fuse
-    the SDM anatomical constraints and multimodal images for refined segmentation.
-    To thoroughly evaluate the performance of our proposed tool, over 700 macaque
-    MRIs from 19 datasets were used in this study. Specifically, we employed two manually
-    labeled longitudinal macaque datasets to develop the tool and complete four-fold
-    cross-validations. Furthermore, we incorporated various external datasets to demonstrate
-    the proposed tool''s generalization capabilities and promise in brain development
-    research. We have made this tool available as an open-source resource at https://github.com/TaoZhong11/Macaque_subcortical_segmentation
-    for direct application.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] CONTEXT: Prognostic prediction models (PPMs) can
-    help clinicians predict outcomes. OBJECTIVE: To critically examine peer-reviewed
-    PPMs predicting delayed recovery among pediatric patients with concussion. DATA
-    SOURCES: Ovid Medline, Embase, Ovid PsycInfo, Web of Science Core Collection,
-    Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Google
-    Scholar. STUDY SELECTION: The study had to report a PPM for pediatric patients
-    to be used within 28 days of injury to estimate risk of delayed recovery at 28
-    days to 1 year postinjury. Studies had to have at least 30 participants. DATA
-    EXTRACTION: The Critical Appraisal and Data Extraction for Systematic Reviews
-    of Prediction Modeling Studies checklist was completed. RESULTS: Six studies of
-    13 PPMs were included. These studies primarily reflected male patients in late
-    childhood or early adolescence presenting to an emergency department meeting the
-    Concussion in Sport Group concussion criteria. No study authors used the same
-    outcome definition nor evaluated the clinical utility of a model. All studies
-    demonstrated high risk of bias. Quality of evidence was best for the Predicting
-    and Preventing Postconcussive Problems in Pediatrics (5P) clinical risk score.
-    LIMITATIONS: No formal PPM Grading of Recommendations, Assessment, Development,
-    and Evaluations (GRADE) process exists. CONCLUSIONS: The 5P clinical risk score
-    may be considered for clinical use. Rigorous external validations, particularly
-    in other settings, are needed. The remaining PPMs require external validation.
-    Lack of consensus regarding delayed recovery criteria limits these PPMs.'
-- source_sentence: '[YEAR_RANGE] 2020-2024 [TEXT] Intraoperative Monitoring of the
-    External Urethral Sphincter Reflex: A Novel Adjunct to Bulbocavernosus Reflex
-    Neuromonitoring for Protecting the Sacral Neural Pathways Responsible for Urination,
-    Defecation and Sexual Function.'
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] OBJECTIVE: The authors examined licensing
+    requirements for select children's behavioral health care providers.
+    METHODS: Statutes and regulations as of October 2021 were reviewed for
+    licensed clinical social workers, licensed professional counselors, and
+    licensed marriage and family therapists for all 50 U.S. states and the
+    District of Columbia. RESULTS: All jurisdictions had laws regarding
+    postgraduate training and license portability. No jurisdiction included
+    language about specialized postgraduate training related to serving children
+    and families or cultural competence. Other policies that related to the
+    structure, composition, and authority of licensing boards varied across
+    states and licensure types. CONCLUSIONS: In their efforts to address
+    barriers to licensure, expand the workforce, and ensure that children have
+    access to high-quality and culturally responsive care, states could consider
+    their statutes and regulations.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Magnetic Resonance Imaging (MRI) plays a
+    pivotal role in the accurate measurement of brain subcortical structures in
+    macaques, which is crucial for unraveling the complexities of brain
+    structure and function, thereby enhancing our understanding of
+    neurodegenerative diseases and brain development. However, due to
+    significant differences in brain size, structure, and imaging
+    characteristics between humans and macaques, computational tools developed
+    for human neuroimaging studies often encounter obstacles when applied to
+    macaques. In this context, we propose an Anatomy Attentional Fusion Network
+    (AAF-Net), which integrates multimodal MRI data with anatomical constraints
+    in a multi-scale framework to address the challenges posed by the dynamic
+    development, regional heterogeneity, and age-related size variations of the
+    juvenile macaque brain, thus achieving precise subcortical segmentation.
+    Specifically, we generate a Signed Distance Map (SDM) based on the initial
+    rough segmentation of the subcortical region by a network as an anatomical
+    constraint, providing comprehensive information on positions, structures,
+    and morphology. Then we construct AAF-Net to fully fuse the SDM anatomical
+    constraints and multimodal images for refined segmentation. To thoroughly
+    evaluate the performance of our proposed tool, over 700 macaque MRIs from 19
+    datasets were used in this study. Specifically, we employed two manually
+    labeled longitudinal macaque datasets to develop the tool and complete
+    four-fold cross-validations. Furthermore, we incorporated various external
+    datasets to demonstrate the proposed tool's generalization capabilities and
+    promise in brain development research. We have made this tool available as
+    an open-source resource at
+    https://github.com/TaoZhong11/Macaque_subcortical_segmentation for direct
+    application.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] CONTEXT: Prognostic prediction models (PPMs)
+    can help clinicians predict outcomes. OBJECTIVE: To critically examine
+    peer-reviewed PPMs predicting delayed recovery among pediatric patients with
+    concussion. DATA SOURCES: Ovid Medline, Embase, Ovid PsycInfo, Web of
+    Science Core Collection, Cumulative Index to Nursing and Allied Health
+    Literature, Cochrane Library, Google Scholar. STUDY SELECTION: The study had
+    to report a PPM for pediatric patients to be used within 28 days of injury
+    to estimate risk of delayed recovery at 28 days to 1 year postinjury.
+    Studies had to have at least 30 participants. DATA EXTRACTION: The Critical
+    Appraisal and Data Extraction for Systematic Reviews of Prediction Modeling
+    Studies checklist was completed. RESULTS: Six studies of 13 PPMs were
+    included. These studies primarily reflected male patients in late childhood
+    or early adolescence presenting to an emergency department meeting the
+    Concussion in Sport Group concussion criteria. No study authors used the
+    same outcome definition nor evaluated the clinical utility of a model. All
+    studies demonstrated high risk of bias. Quality of evidence was best for the
+    Predicting and Preventing Postconcussive Problems in Pediatrics (5P)
+    clinical risk score. LIMITATIONS: No formal PPM Grading of Recommendations,
+    Assessment, Development, and Evaluations (GRADE) process exists.
+    CONCLUSIONS: The 5P clinical risk score may be considered for clinical use.
+    Rigorous external validations, particularly in other settings, are needed.
+    The remaining PPMs require external validation. Lack of consensus regarding
+    delayed recovery criteria limits these PPMs.
+- source_sentence: >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Intraoperative Monitoring of the External
+    Urethral Sphincter Reflex: A Novel Adjunct to Bulbocavernosus Reflex
+    Neuromonitoring for Protecting the Sacral Neural Pathways Responsible for
+    Urination, Defecation and Sexual Function.
   sentences:
-  - '[YEAR_RANGE] 2020-2024 [TEXT] Early menarche has been associated with adverse
-    health outcomes, such as depressive symptoms. Discovering effect modifiers across
-    these conditions in the pediatric population is a constant challenge. We tested
-    whether movement behaviours modified the effect of the association between early
-    menarche and depression symptoms among adolescents. This cross-sectional study
-    included 2031 females aged 15-19 years across all Brazilian geographic regions.
-    Data were collected using a self-administered questionnaire; 30.5% (n = 620) reported
-    having experienced menarche before age 12 years (that is, early menarche). We
-    used the Patient Health Questionnaire (PHQ-9) to evaluate depressive symptoms.
-    Accruing any moderate-vigorous physical activity during leisure time, limited
-    recreational screen time, and having good sleep quality were the exposures investigated.
-    Adolescents who experienced early menarche and met one (B: -4.45, 95% CI: (-5.38,
-    -3.51)), two (B: -6.07 (-7.02, -5.12)), or three (B: -6.49 (-7.76, -5.21)), and
-    adolescents who experienced not early menarche and met one (B: -5.33 (-6.20; -4.46)),
-    two (B: -6.12 (-6.99; -5.24)), or three (B: -6.27 (-7.30; -5.24)) of the movement
-    behaviour targets had lower PHQ-9 scores for depression symptoms than adolescents
-    who experienced early menarche and did not meet any of the movement behaviours.
-    The disparities in depressive symptoms among the adolescents (early menarche versus
-    not early menarche) who adhered to all three target behaviours were not statistically
-    significant (B: 0.41 (-0.19; 1.01)). Adherence to movement behaviours modified
-    the effect of the association between early menarche and depression symptoms.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] PURPOSE: Intraoperative bulbocavernosus reflex
-    neuromonitoring has been utilized to protect bowel, bladder, and sexual function,
-    providing a continuous functional assessment of the somatic sacral nervous system
-    during surgeries where it is at risk. Bulbocavernosus reflex data may also provide
-    additional functional insight, including an evaluation for spinal shock, distinguishing
-    upper versus lower motor neuron injury (conus versus cauda syndromes) and prognosis
-    for postoperative bowel and bladder function. Continuous intraoperative bulbocavernosus
-    reflex monitoring has been utilized to provide the surgeon with an ongoing functional
-    assessment of the anatomical elements involved in the S2-S4 mediated reflex arc
-    including the conus, cauda equina and pudendal nerves. Intraoperative bulbocavernosus
-    reflex monitoring typically includes the electrical activation of the dorsal nerves
-    of the genitals to initiate the afferent component of the reflex, followed by
-    recording the resulting muscle response using needle electromyography recordings
-    from the external anal sphincter. METHODS: Herein we describe a complementary
-    and novel technique that includes recording electromyography responses from the
-    external urethral sphincter to monitor the external urethral sphincter reflex.
-    Specialized foley catheters embedded with recording electrodes have recently become
-    commercially available that provide the ability to perform intraoperative external
-    urethral sphincter muscle recordings. RESULTS: We describe technical details and
-    the potential utility of incorporating external urethral sphincter reflex recordings
-    into existing sacral neuromonitoring paradigms to provide redundant yet complementary
-    data streams. CONCLUSIONS: We present two illustrative neurosurgical oncology
-    cases to demonstrate the utility of the external urethral sphincter reflex technique
-    in the setting of the necessary surgical sacrifice of sacral nerve roots.'
-  - '[YEAR_RANGE] 2020-2024 [TEXT] BACKGROUND: Limited data are available on the appropriate
-    choice of blood pressure management strategy for patients with acute basilar artery
-    occlusion assessed by the standard deviation (SD). Multivariate logistic models
-    were used to investigate the association between BPV, the primary outcome (futile
-    recanalization, 90-day modified Rankin Scale score 3-6), and the secondary outcome
-    (30-day mortality). Subgroup analysis was performed as a sensitivity test. RESULTS:
-    Futile recanalization occurred in 60 (56 %) patients, while 26 (24 %) patients
-    died within 30 days. In the fully adjusted model, MAP SD was associated with a
-    higher risk of futile recanalization (OR adj=1.36, per 1 mmHg increase, 95 % CI:
-    1.09-1.69, P=0.006) and 30-day mortality (OR adj=1.56, per 1 mmHg increase, 95
-    % CI: 1.20-2.04, P=0.001). A significant interaction between MAP SD and the lack
-    of hypertension history on futile recanalization (P<0.05) was observed. CONCLUSIONS:
-    Among recanalized acute BAO ischemic patients, higher blood pressure variability
-    during the first 24 h after MT was associated with worse outcomes. This association
-    was stronger in patients without a history of hypertension.'
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] Early menarche has been associated with
+    adverse health outcomes, such as depressive symptoms. Discovering effect
+    modifiers across these conditions in the pediatric population is a constant
+    challenge. We tested whether movement behaviours modified the effect of the
+    association between early menarche and depression symptoms among
+    adolescents. This cross-sectional study included 2031 females aged 15-19
+    years across all Brazilian geographic regions. Data were collected using a
+    self-administered questionnaire; 30.5% (n = 620) reported having experienced
+    menarche before age 12 years (that is, early menarche). We used the Patient
+    Health Questionnaire (PHQ-9) to evaluate depressive symptoms. Accruing any
+    moderate-vigorous physical activity during leisure time, limited
+    recreational screen time, and having good sleep quality were the exposures
+    investigated. Adolescents who experienced early menarche and met one (B:
+    -4.45, 95% CI: (-5.38, -3.51)), two (B: -6.07 (-7.02, -5.12)), or three (B:
+    -6.49 (-7.76, -5.21)), and adolescents who experienced not early menarche
+    and met one (B: -5.33 (-6.20; -4.46)), two (B: -6.12 (-6.99; -5.24)), or
+    three (B: -6.27 (-7.30; -5.24)) of the movement behaviour targets had lower
+    PHQ-9 scores for depression symptoms than adolescents who experienced early
+    menarche and did not meet any of the movement behaviours. The disparities in
+    depressive symptoms among the adolescents (early menarche versus not early
+    menarche) who adhered to all three target behaviours were not statistically
+    significant (B: 0.41 (-0.19; 1.01)). Adherence to movement behaviours
+    modified the effect of the association between early menarche and depression
+    symptoms.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] PURPOSE: Intraoperative bulbocavernosus reflex
+    neuromonitoring has been utilized to protect bowel, bladder, and sexual
+    function, providing a continuous functional assessment of the somatic sacral
+    nervous system during surgeries where it is at risk. Bulbocavernosus reflex
+    data may also provide additional functional insight, including an evaluation
+    for spinal shock, distinguishing upper versus lower motor neuron injury
+    (conus versus cauda syndromes) and prognosis for postoperative bowel and
+    bladder function. Continuous intraoperative bulbocavernosus reflex
+    monitoring has been utilized to provide the surgeon with an ongoing
+    functional assessment of the anatomical elements involved in the S2-S4
+    mediated reflex arc including the conus, cauda equina and pudendal nerves.
+    Intraoperative bulbocavernosus reflex monitoring typically includes the
+    electrical activation of the dorsal nerves of the genitals to initiate the
+    afferent component of the reflex, followed by recording the resulting muscle
+    response using needle electromyography recordings from the external anal
+    sphincter. METHODS: Herein we describe a complementary and novel technique
+    that includes recording electromyography responses from the external
+    urethral sphincter to monitor the external urethral sphincter reflex.
+    Specialized foley catheters embedded with recording electrodes have recently
+    become commercially available that provide the ability to perform
+    intraoperative external urethral sphincter muscle recordings. RESULTS: We
+    describe technical details and the potential utility of incorporating
+    external urethral sphincter reflex recordings into existing sacral
+    neuromonitoring paradigms to provide redundant yet complementary data
+    streams. CONCLUSIONS: We present two illustrative neurosurgical oncology
+    cases to demonstrate the utility of the external urethral sphincter reflex
+    technique in the setting of the necessary surgical sacrifice of sacral nerve
+    roots.
+  - >-
+    [YEAR_RANGE] 2020-2024 [TEXT] BACKGROUND: Limited data are available on the
+    appropriate choice of blood pressure management strategy for patients with
+    acute basilar artery occlusion assessed by the standard deviation (SD).
+    Multivariate logistic models were used to investigate the association
+    between BPV, the primary outcome (futile recanalization, 90-day modified
+    Rankin Scale score 3-6), and the secondary outcome (30-day mortality).
+    Subgroup analysis was performed as a sensitivity test. RESULTS: Futile
+    recanalization occurred in 60 (56 %) patients, while 26 (24 %) patients died
+    within 30 days. In the fully adjusted model, MAP SD was associated with a
+    higher risk of futile recanalization (OR adj=1.36, per 1 mmHg increase, 95 %
+    CI: 1.09-1.69, P=0.006) and 30-day mortality (OR adj=1.56, per 1 mmHg
+    increase, 95 % CI: 1.20-2.04, P=0.001). A significant interaction between
+    MAP SD and the lack of hypertension history on futile recanalization
+    (P<0.05) was observed. CONCLUSIONS: Among recanalized acute BAO ischemic
+    patients, higher blood pressure variability during the first 24 h after MT
+    was associated with worse outcomes. This association was stronger in
+    patients without a history of hypertension.
+base_model:
+- pankajrajdeo/UMLS-ED-Bioformer-16L-V-1.25-SpecialTokensUntrained
 ---
 
 # SentenceTransformer
@@ -346,8 +409,6 @@ This is a [sentence-transformers](https://www.SBERT.net) model trained on the pa
 
 ## Model Details
 
-**BASE MODEL:** pankajrajdeo/UMLS-ED-Bioformer-16L-V-1.5-SpecialTokensUntrained
-
 ### Model Description
 - **Model Type:** Sentence Transformer
 <!-- - **Base model:** [Unknown](https://huggingface.co/unknown) -->