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\n1 \u9001\u68c0\u4fe1\u606f 1 1. 2 \u68c0\u6d4b\u9879\u76ee\u53ca\u7ed3\u679c 1 1. 3 \u4e34\u5e8a\u7528\u836f\u63d0\u793a 2 1. 3. 1 \u9776\u5411\u7528\u836f\u63d0\u793a 2 1. 3. 2 \u514d\u75ab\u7528\u836f\u63d0\u793a 2 1. 3. 3 \u5316\u7597\u7528\u836f\u63d0\u793a 2 02 \u68c0\u6d4b\u7ed3\u679c\u8be6\u7ec6\u89e3\u8bfb 2. 1 \u4e34\u5e8a\u5e38\u89c4\u9776\u5411\u836f\u7269\u57fa\u56e0\u68c0\u6d4b\u7ed3\u679c 3 2. 2 \u9776\u5411\u57fa\u56e0\u7ed3\u679c\u89e3\u8bfb 4 2. 3 \u514d\u75ab\u6cbb\u7597\u76f8\u5173\u68c0\u6d4b\u7ed3\u679c\u89e3\u8bfb 9 2. 3. 1 \u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB\uff09 9 2. 3. 2 \u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\uff08MSI\uff09 11 2. 3. 3 DNA \u9519\u914d\u4fee\u590d\u57fa\u56e0\uff08MMR\uff09 12 2. 3.\n \u51fa\u5904 [3] xx_ZL0123936.pdf
\n\u7528\u836f\u9700\u9075\u533b\u5631\uff0c\u8c28\u614e\u7528\u836f\u3002 1. 3. 3 \u5316\u7597\u7528\u836f\u63d0\u793a \u5177\u4f53\u5206\u6790\u7ed3\u679c\u89c1 2. 4\u8282\u3002 \u5b89\u5fbd\u7701\u5408\u80a5\u5e02\u5e90\u9633\u533a\u961c\u9633\u5317\u8def\u4e0e\u5317\u57ce\u5927\u9053\u4ea4\u53e3\u521b\u667a\u5929\u5730 A6 \u53f7\u697c (400-801-9858) \u7b2c 2 \u9875/\u5171 36 \u9875 \u59d3\u540d\uff1a\u8096\u84d3 | \u62a5\u544a\u7f16\u53f7\uff1a502491 \u5b89\u62e9\u5eb7 \u00ae 02\u68c0\u6d4b\u7ed3\u679c\u8be6\u7ec6\u89e3\u8bfb Detailed analysis of test results 2. 1\u4e34\u5e8a\u5e38\u89c4\u9776\u5411\u836f\u7269\u57fa\u56e0\u68c0\u6d4b\u7ed3\u679c \u672c\u5217\u8868\u5c55\u793a\u6307\u5357\u53ca\u5171\u8bc6\u63a8\u8350\u68c0\u6d4b\u5b9e\u4f53\u7624\u76f8\u5173\u70ed\u70b9\u57fa\u56e0\u7684\u7a81\u53d8\u60c5\u51b5\uff1a AKT1 \u70b9\u7a81\u53d8 \u9634\u6027 - - ALK \n \u51fa\u5904 [4] xx_ZL0123936.pdf
\n3. 4 \u6f5c\u5728\u5f71\u54cd\u514d\u75ab\u6cbb\u7597\u7597\u6548\u7684\u57fa\u56e0\u68c0\u6d4b\u7ed3\u679c \u5b89\u62e9\u5eb7\u2013NGS \u5b9e\u4f53\u7624 658 \u57fa\u56e0 TMB \u68c0\u6d4b\u5305\u542b\u4e0e\u514d\u75ab\u6cbb\u7597\u7597\u6548\u76f8\u5173\u57fa\u56e0\uff1a\u6b63\u76f8\u5173\u3001\u8d1f\u76f8\u5173\u4ee5\u53ca\u8d85\u8fdb\u5c55\u76f8\u5173\u57fa\u56e0\uff0c \u8fd9\u4e9b\u57fa\u56e0 \u6765\u6e90\u4e8e\u90e8\u5206\u764c\u79cd\u7684\u4e34\u5e8a\u524d\u6216\u521d\u671f\u7814\u7a76\u7ed3\u679c\uff0c \u68c0\u6d4b\u7ed3\u679c\u4ec5\u4f9b\u4e34\u5e8a\u53c2\u8003\u3002 \u3010\u5b9e\u4f53\u7624\u3011 MLH1 \u6b63\u76f8\u5173 \u672a\u89c1\u76f8\u5173\u53d8\u5f02 - - DNA \u9519\u914d\u4fee\u590d\u57fa\u56e0\uff08MMR\uff09\u53d1\u751f\u81f4\u75c5\u6216\u7591\u4f3c\u81f4\u75c5\u53d8\u5f02 \u65f6\uff0c\u53ef\u80fd\u4f1a\u5bfc\u81f4 MSI-H \u6216 dMMR\uff0c\u4e0e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236 \u5242\uff08ICIs\uff09\u7597\u6548\u5448\u6b63\u76f8\u5173\u3002\n "], ["\u836f\u7269\u8be2\u8bc1\u662f\u6307\u4ec0\u4e48\uff1f", "\u836f\u7269\u8be2\u8bc1\u662f\u6307\u9488\u5bf9\u53d7\u68c0\u8005\u80bf\u7624\u7c7b\u578b\uff0c\u6240\u5217\u751f\u7269\u6807\u5fd7\u7269\u4e0e\u836f\u7269\u54cd\u5e94\u5173\u7cfb\u7684\u8bc1\u636e\u6765\u6e90\u3002\u672c\u62a5\u544a\u6240\u91c7\u7528\u836f\u7269\u8be2\u8bc1\u7b49\u7ea7\u662f\u5728\u80bf\u7624\u7cbe\u51c6\u7528\u836f\u6570\u636e\u5e93 OncoKB \u836f\u7269\u8be2\u8bc1\u7b49\u7ea7\u7684\u57fa\u7840\u4e0a\uff0c\u878d\u5165 NMPA \u836f\u54c1\u8bf4\u660e\u4e66\u53ca\u56fd\u5185\u6307\u5357\u5171\u8bc6\u53ca\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u636e\uff0c\u5171\u5212\u5206\u4e3a 6 \u4e2a\u7b49\u7ea7\uff0c\u5305\u62ec\u672c\u764c\u79cd\u7528\u836f\u63d0\u793a\u654f\u611f\u5305\u62ec 1 \u7ea7\u548c 2 \u7ea7\u8be2\u8bc1\u836f\u7269\uff0c\u53ef\u80fd\u654f\u611f\u5305\u62ec 3A \u7ea7\u548c 4 \u7ea7\u8be2\u8bc1\u836f\u7269\uff0c\u6f5c\u5728\u8010\u836f\u5305\u62ec R1 \u7ea7\u548c R2 \u7ea7\u8be2\u8bc1\u836f\u7269\u3002
\n \u51fa\u5904 [1] xx_ZL0123936.pdf
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\n R2 \u7ea7\uff1a\u672c\u764c\u79cd\u4e2d\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u793a\u8be5\u751f\u7269\u6807\u5fd7\u7269\u53ef\u80fd\u5bfc\u81f4\u8010\u836f\uff1b \u6216\u5176\u4ed6\u764c\u79cd\u7684\u836f\u54c1\u8bf4\u660e\u4e66\u6216\u6307\u5357\u6307\u51fa\u8be5\u751f\u7269\u6807\u5fd7\u7269\u9884\u6d4b\u540c\u79cd\u836f \u7269\u7684\u8010\u836f\u6027\u3002 2. \u7a81\u53d8\u4e30\u5ea6\uff1a\u67d0\u4e2a\u57fa\u56e0\u4f4d\u70b9\u7684\u7a81\u53d8\u7b49\u4f4d\u57fa\u56e0\u5360\u6240\u6709\u7b49\u4f4d\u57fa\u56e0\u7684\u6bd4\u4f8b\uff0c\u5373\u7b49\u4e8e\u7a81\u53d8\u578b/\uff08\u7a81\u53d8\u578b + \u91ce\u751f\u578b\uff09\uff0c\u4e00\u822c\u9488\u5bf9\u70b9\u7a81\u53d8\u6216 \u5c0f\u7247\u6bb5\u63d2\u5165\u7f3a\u5931\u60c5\u51b5\uff1b \u62f7\u8d1d\u6570\uff1a\u53d7\u68c0\u8005\u57fa\u56e0\u62f7\u8d1d\u6570\u53d8\u5316\u60c5\u51b5\uff0c\u4ee5 2 \u4e3a\u6b63\u5e38\u503c\u3002 \u7a81\u53d8\u4e30\u5ea6\u548c\u62f7\u8d1d\u6570\u53d7\u80bf\u7624\u7ec6\u80de\u542b\u91cf\u548c\u53d6\u6750\u7b49\u56e0 \u7d20\u7684\u5f71\u54cd\u3002 3. \u672c\u62a5\u544a\u68c0\u6d4b\u7ed3\u679c\u53ca\u7528\u836f\u63a8\u8350\u4ec5\u4f9b\u4e34\u5e8a\u53c2\u8003\uff0c\u5177\u4f53\u9700\u4e34\u5e8a\u533b\u751f\u7ed3\u5408\u60a3\u8005\u5b9e\u9645\u60c5\u51b5\u786e\u5b9a\u5408\u7406\u7684\u6cbb\u7597\u65b9\u6848\u3002\n \u51fa\u5904 [2] xx_ZL0123936.pdf
\n 3. \u7ed3\u679c\u63d0\u793a\uff1a\u82e5\u68c0\u6d4b\u7ed3\u679c\u4e3a MSI-H\uff0c\u63d0\u793a\u4ece\u514d\u75ab\u6cbb\u7597\u4e2d\u83b7\u76ca\u53ef\u80fd\u6027\u8f83\u9ad8\uff1b \u82e5\u68c0\u6d4b\u7ed3\u679c\u4e3a MSS\uff0c\u63d0\u793a\u4ece\u514d\u75ab\u6cbb\u7597\u4e2d\u83b7\u76ca\u53ef\u80fd\u6027 \u8f83\u4f4e\uff0c\u9700\u7ed3\u5408\u5176\u4ed6\u6307\u6807\u7efc\u5408\u8bc4\u4f30\u7528\u836f\u3002 \u6807\u5fd7\u7269\u89e3\u6790\uff1a 1. \u59d3\u540d\uff1a\u8096\u84d3 | \u62a5\u544a\u7f16\u53f7\uff1a502491 \u5b89\u62e9\u5eb7 \u00ae 2. 3. 3 DNA \u9519\u914d\u4fee\u590d\u57fa\u56e0\uff08MMR\uff09 - - DNA \u9519\u914d\u4fee\u590d\u57fa\u56e0\uff08MMR\uff09- - \u57fa\u56e0 \u5916\u663e\u5b50 \u6838\u82f7\u9178\u53d8\u5f02 \u6c28\u57fa\u9178\u53d8\u5f02 \u7a81\u53d8\u4e30\u5ea6 \u4e34\u5e8a\u610f\u4e49 \u7a81\u53d8\u6765\u6e90 MLH1 - - - - - - - - - - - - MSH2 - - - \n \u51fa\u5904 [3] xx_ZL0123936.pdf
\n636G>A p. A212A 1. 70% COSV58998843 \u201c.\u201d\u8868\u793a\u8be5\u7a81\u53d8\u672a\u6709 cosmic \u6570\u636e\u5e93\u8bb0\u5f55 - - \u57fa\u56e0\u62f7\u8d1d\u6570\u5206\u6790\u7ed3\u679c - - \u57fa\u56e0 \u67d3\u8272\u4f53\u4f4d\u7f6e \u62f7\u8d1d\u6570 JUN chr1 9. 03 - - \u57fa\u56e0\u91cd\u6392\u5206\u6790\u7ed3\u679c - - 5 \u2032 \u7aef\u7a81\u53d8 3 \u2032 \u7aef\u7a81\u53d8 \u53d8\u5f02 \u57fa\u56e0 \u8f6c\u5f55\u672c \u5916\u663e\u5b50 \u57fa\u56e0 \u8f6c\u5f55\u672c \u5916\u663e\u5b50 \u7a81\u53d8\u4e30\u5ea6 - - - - - - - - - - - - - - - - \u5b89\u5fbd\u7701\u5408\u80a5\u5e02\u5e90\u9633\u533a\u961c\u9633\u5317\u8def\u4e0e\u5317\u57ce\u5927\u9053\u4ea4\u53e3\u521b\u667a\u5929\u5730 A6 \u53f7\u697c (400-801-9858) \u7b2c 25 \u9875/\u5171 36 \u9875 \u59d3\u540d\uff1a\u8096\u84d3 | \u62a5\u544a\u7f16\u53f7\uff1a502491 \u5b89\u62e9\u5eb7 \u00ae - - \u80da\u7cfb\u81f4\u75c5\u6027\u53d8\u5f02\u5206\u6790\u7ed3\u679c - - \u57fa\u56e0 \u8f6c\u5f55\u672c \u5916\u663e\u5b50 \u6838\u82f7\u9178\u53d8\u5f02 \u6c28\u57fa\u9178\u53d8\u5f02 \u7a81\u53d8\u4e30\u5ea6 \u4e34\u5e8a\u610f\u4e49 - - - - - - - - - - - - - - - - \u672a\u68c0\u6d4b\u5230\u53d8\u5f02\u7684\u70ed\u70b9\u57fa\u56e0 - - CDKN2B PDGFRA SMAD4 HRAS ATM EGFR RET CTNNB1 AKT1 MAP2K1 EZH2 RAD51B EPCAM FH BRIP1 TSC2 ROS1 TSC1 RAD51D BAP1 \n "]]