diff --git "a/cohort_past_history_12072022.csv" "b/cohort_past_history_12072022.csv" new file mode 100644--- /dev/null +++ "b/cohort_past_history_12072022.csv" @@ -0,0 +1,135702 @@ +SUBJECT_ID,INDEX_HADM_ID,INDEX_ROW_ID,INDEX_CHARTDATE,ROW_ID,HADM_ID,CHARTDATE,CATEGORY,TEXT,days_from_index,ADMITTIME,DISCHTIME,ADMISSION_TYPE,ADMISSION_LOCATION,DISCHARGE_LOCATION,DIAGNOSIS,hospital_course_processed,Diagnosis_Description +109,140167.0,14802,2141-12-23,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",100,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,140167.0,14802,2141-12-23,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",90,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,140167.0,14802,2141-12-23,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",50,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,140167.0,14802,2141-12-23,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",30,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,140167.0,14802,2141-12-23,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",22,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,140167.0,14802,2141-12-23,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",9,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,173633.0,14801,2141-12-14,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",91,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,173633.0,14801,2141-12-14,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",81,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,173633.0,14801,2141-12-14,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",41,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,173633.0,14801,2141-12-14,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",21,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,173633.0,14801,2141-12-14,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",13,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,173633.0,14801,2141-12-14,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",97,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,140167.0,14802,2141-12-23,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",106,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,124657.0,14804,2142-01-20,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",118,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,124657.0,14804,2142-01-20,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",78,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,124657.0,14804,2142-01-20,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",58,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,124657.0,14804,2142-01-20,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",50,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,124657.0,14804,2142-01-20,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",37,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,124657.0,14804,2142-01-20,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",28,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,124657.0,14804,2142-01-20,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",8,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,135923.0,14803,2142-01-12,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",120,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,135923.0,14803,2142-01-12,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",110,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,135923.0,14803,2142-01-12,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",70,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,135923.0,14803,2142-01-12,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",50,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,135923.0,14803,2142-01-12,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",42,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,135923.0,14803,2142-01-12,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",29,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,135923.0,14803,2142-01-12,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",20,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,135923.0,14803,2142-01-12,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",126,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,124657.0,14804,2142-01-20,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",134,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,161950.0,14800,2141-12-01,15329,147469.0,2141-06-17,Discharge summary,"Admission Date: [**2141-6-11**] Discharge Date: [**2141-6-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +hypertensive urgency + +Major Surgical or Invasive Procedure: +arterial line + +History of Present Illness: +HPI: 23 F with h/o Lupus, ESRD not on HD (planned PD), labile +hypertension, RUE VTE on anticoagulation, recent facial swelling +who presents with hypertensive emergency. Patient developed +severe frontal HA last evenening, a/w nausea. BP was not [**Location (un) 1131**] +on home BP cuff. In the AM her HA was severe [**10-20**] a/w nausea +and vomiting yellow/green liquid and BP cuff again not able to +obtain BP. Patient was last seen by VNA this past Friday with BP +130/70. Patient denies any CP, shortness of breath, abd pain. +Her facial swelling is slightly worse today. She denies any +weakness, dizziness, difficulty with speach, no numbness or +tingling. She says that she is compliant with all of her +medications. She denies any GU/GI complaints despite +UA in ED. + +. +In the ED, VS: 98.2 92 SBP >300/P [**Telephone/Fax (3) 44541**]-131) 16 98 % RA. +Patient received zofran IV, Hydral IV, Labetalol 20 mg IV x 1, +Nipride gtt started. Kayexalate 30 mg x 1. Other po meds written +but patient did not take due to nausea. CT head showing no +hemorrhage but hypoattenuation in frontal area, which is change +from prior MRI in [**Month (only) **]. She is on coumadin for RUE VTE with +INR 2.1. Also with UTI in ED, started Cirpo x 1. Labs showing K +5.6 ECG with ?hyperacute T waves, otherwise no changes, given +kayexalate only. +. +Interval Hx: Patient was admitted [**2141-5-24**] to [**6-6**] with facial +swelling and hypertensive emergency requiring ICU care. She was +also admitted [**Date range (1) 43498**] with similar complaints. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 98.8 84 [**Telephone/Fax (2) 44542**]% RA +Gen: swollen face L>R, alert and cooperative, NAD, snoring when +asleep but easily arousable +Heent: OP clear, swollen eye lids L>R, Left eye retracted with +prosthesis, anicteric, OP moist +Neck: supple, no JVD elevation, no meningismus +CV: nl S1 S2, RRR, [**1-15**] SM +Lungs: CTAB +Abd: obese, soft, NT, ND, BS+ +Ext: dry, no c/c/e, diminished, +Neuro: Alert and oriented x 3, gets drowsy intermittently but +arousable, CN II-XII intact, strength 5/5 throughout, sensations +intact + + +Pertinent Results: +[**6-14**]: AXR:IMPRESSION: PD catheter with tip coiled in the pelvis. +[**6-11**]: IMPRESSION: 1. Areas of hypoattenuation in the high +bifrontal white matter, and subcortical hypoattenuation in the +left posterior temporal lobe with loss of [**Doctor Last Name 352**]-white +differentiation. These findings are new from MRI brain [**12-29**], [**2140**], and could represent areas of new edema with underlying +focal lesion or possibly areas of new infarcts. An MRI head +without and with Iv conrast is recommended for further +characterization. +2. No evidence of intracranial hemorrhage. + +[**6-11**]: PA AND LATERAL VIEWS OF THE CHEST: There has been an +interval increase in retrocardiac opacity obscuring the left +hemidiaphragm. The right lung and the left upper lung zone are +clear. The right costophrenic angle is slightly blunted, +suggesting a very small right pleural effusion. The heart is +slightly enlarged, but the cardiomediastinal silhouette is +unchanged. There is no hilar enlargement. Soft tissue and bony +structures are unremarkable. + +IMPRESSION: Interval increase in left basilar atelectasis with +pleural effusion. Superimposed pneumonia cannot be excluded. +Possible small right pleural effusion. + +[**6-11**]: MR [**Name13 (STitle) 430**]: INDINGS: In comparison with a prior CT of the +head, the previously described low attenuation areas in the +parietal regions appear with hyperintensity signal on the FLAIR +sequence, mildly hyperintense on the diffusion-weighted +sequence, and also slightly hyperintense on the corresponding +ADC maps, these findings are nonspecific and may represent +posterior reversible encephalopathic changes, please correlate +clinically. There is no evidence of acute hemorrhage, +hydrocephalus, or midline shift. A low-attenuation area is +identified on the right occipital region, likely consistent with +chronic deposits of hemosiderin, please correlate with the prior +MRI dated [**2140-12-28**]. + +IMPRESSION: Limited examination secondary to motion artifacts. +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. The prior low-attenuation area of the +right occipital lobe is unchanged and may represent chronic +deposits of hemosiderin. There is no evidence of hydrocephalus +or midline shifting. Followup with MRI of the head with and +without contrast under conscious sedation is recommended if +clinically warranted. + +Brief Hospital Course: +A/P: 23 F with SLE, ESRD not on HD, chronic VTE with RUE and +facial swelling p/w hypertensive emergency and delta MS +initially admitted to the [**Hospital Unit Name 153**]. + +In the [**Hospital Unit Name 153**] she was on a labetalol gtt as well as home +medications. She had head imaging (MRI) with following results; +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. She was evaluated by neurology who +considered PRES, though she did not seize. She was started on +keppra as she has had seizures before, and will follow up with +them. +. +# HTN Emergency. She has had multiple admissions in the past +with neurological involvement, hemolysis in the past. SBP >300 +in ED. Her BP was lowered slowly with a labetolol gtt in the +ICU. When it was stably below 180 she was transferred to the +medical floor on the [**Hospital Ward Name 517**]. She was continued on +clonidine TP, po labetalol, aliskiren. I/O goal was even. Her +BP remained between 120-170 before discharge, she no longer had +any headaches, or nausea. She was oriented times three. +Aliskiren was not covered by masshealth, and a prior auth was +faxed over. A supply from the pharmacy was sought but +unavailable. She was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. She was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# Delta MS. [**2-11**] to hypertension likely ischemic/hypertensive +changes on CT. AAO times three, no focal neurological signs +currently. Also likely component of OSA although this seems +chronic. No seizures although has had them in the past. +Neuro was consulted, and she was started on Keppra for question +of PRES, keppra for 6 weeks until f/u with neuro, has outpatient +MRI appointment as well. They will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#UTI-found on admission, was on Cipro-will complete course of 5 +days +. +# VTE. L Brachiocephalic VTE chronic with collaterals. Also h/o +other VTE [**2-11**] to lines in the past. Currently on coumadin. INR +2.1 coumadin was held in [**Hospital Unit Name 153**] for anticipation of procedures. +Her coumadin was restarted, has VNA set up and will be followed +by [**Hospital3 **]. +. +# Facial Swelling. Unclear etiology likely [**2-11**] to VTE in RUE +(brachiocephalic) vs. angioedema-pt now without swelling +. +# ESRD. Currently no on HD due to patient preference, awaiting +to start PD next week. Since patient has refused HD there was an +attempt to correct lytes and acid base with medications. Avoided +fluid overload with lasix, patient currently making urine. Lytes +- see below. She will commence PD as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on Monday. Her +ACE/[**Last Name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# Metabolic Acidosis/Electrolytes abnormalities. AG 15 likely +[**2-11**] to uremia. K elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. She received +kayexalate 30 mg tid until K <5 +Her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# SLE. On prednisone chronically, likely needs PCP [**Name9 (PRE) **] at some +point --Atovaquone to prevent hyperkalemia +Continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# Anemia-Hct and plts dropped on this admission but now stable + +. +# HOCM. Avoid dehydration. Currently on Labetalol. +. +# PPX: systemically anticoagulated, getting kayexalate, PPI +# FEN: Electrolytes as above, no standing fluids I/Os goal even. + +# Access: 2x PIV currently +# Code: Full +# Dispo: home + + +Medications on Admission: + Pantoprazole 40 mg daily +- Clonidine TP 0.3/24 hrs q wednesday +- Prednisone 10 mg daily (just decreased from 15 mg) +- Calcitriol 0.25 mcg daily +- Sodium bicarbonate 650 mg 2 tabs daily +- Vit D3 400 mg daily +- Vit D2 50,000 q wed, x 10 weeks +- Labetalol 300 mg po 3 tabs TID +- Nifedipine SR 90 mg [**Hospital1 **] +- Warfarin 2 mg daily +- Hydral 25 mg TID +- Lasix 40 mg [**Hospital1 **] (started friday) +- Benadryl 25 mg po prn +- Ativan 1 mg [**Hospital1 **] prn +- Colace 100 mg [**Hospital1 **] prn +- Morphine 15 mg po q 6 hrs x 14 days +- Diovan 320 mg daily +- Dilaudid prn + + +Discharge Medications: +1. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +on alternating days with 15mg. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed. +4. Levetiracetam 250 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*60 Capsule(s)* Refills:*2* +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +Disp:*60 Tablet(s)* Refills:*0* +7. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day): please take as directed when blood pressure is above +180. +Disp:*90 Tablet(s)* Refills:*2* +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +9. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +Disp:*405 Tablet(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO BID (2 times a day). +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) +as needed for hold for sbp < 130. +Disp:*10 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +14. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO TID +(3 times a day). +15. Outpatient Lab Work +for [**Known firstname **] [**Known lastname **] DOB [**2117-8-7**] +please check INR once a week and have results faxed to +[**Hospital3 **] at [**Hospital1 18**] phone-[**Telephone/Fax (1) 14650**], fax-[**Telephone/Fax (1) 44543**] +16. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO once a day: +hold for sbp<130. +Disp:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +-hypertensive emergency +-Lupus - [**2134**]. Diagnosed after she began to have swolen fingers, +a rash and painful joints. +-ESRD secodary to SLE - [**2135**]. Was initially on cytoxan, 1 dose +every 3 months for 2 years until began dialysis 3 times a week +in [**2137**] (T, Th, Sat). Now no longer on Hemodialysis, with +hyperkalemia/Hypocalcemia/Hyperphosphatemia/Elevated +PTH/Metabolic Acidosis; PD Catheter placed [**5-18**] +-h/o seizures, ICU admissions; h/o two intraparenchymal +hemorrhages that were thought due to the posterior reversible +leukoencephalopathy syndrome, associated with LE paresis in [**2140**] +that resolved +-Uveitis secondary to SLE - [**4-16**]; s/p surgery [**2-16**]; she had +blood cleared and cataract removed as well as glaucoma. +-HOCM - per Echo in [**2137**] +-Mulitple episodes of dialysis reactions +-Anemia +-H/O SVC thrombus [**10-16**] [**2-11**] catheter placement, was on coumadin +then stopped; Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], +[**9-/2140**]); Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]); Negative Beta-2 glycoprotein antibody ([**4-/2138**], +[**8-/2140**]) +-Facial and left breast swelling - attributed to angioedema vs +chronic L Brachiocephalic vein occlusion +-Thrombophilia ?????? likely related to SLE, h/o recurrent VTE +-Thrombocytopenia NOS +-TTP (got plasmapheresisis) versus malignant HTN +-History of left eye enucleation [**2139-4-20**] for fungal infection + + +Discharge Condition: +stable, afebrile, SBP 120's-170's + + +Discharge Instructions: +You were admitted with hypertensive emergency, your blood +pressure was extremely high. You had a head CT and MRI that +showed some changes concerning for PRES (posterior reversible +leukoencephalopathy syndrome), and neurology recommended +initiating Keppra. Your blood pressure was brought under +control in the intensive care unit and now you have a new +regimen of medications. In addition peritoneal dialysis was +attempted but there were difficulties with your catheter. This +will be further addressed by your outpatient nephrologist. You +will continue to have your INR drawn and sent to coumadin +clinic. +You should take all your medications as prescribed, you will be +taking the keppra until you follow up with a neurologist in +approximately 6 weeks. You will also be taking the Aliskiren +following discharge. You will be discharged on hydralazine +(which you will take three times daily EVERY DAY), as well as +when your blood pressure gets too high as follows; +if you blood pressure is above 180 please take an extra dose of +hydralazine, check your blood pressure in 10 minutes, if it is +still not take another dose and recheck your blood pressure in +another 10 minutes-if it is still elevated take another 25mg +hydralazine and recheck in 10 minutes-if it is still elevated +please call your doctor or go to the ER. +Continue taking your coumadin and having your INR sent to +coumadin clinic. +Please seek medication attention if you have any headaches, +chest pain, shortness of breath, dizzyness, nausea or any other +concerning symptoms. +Please follow up as outlined below. + +Followup Instructions: +-Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Name12 (NameIs) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2141-6-30**] +10:00 +-Your renal team will contact you regarding follow up-you should +call CB for home teaching. +-Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-7-12**] 10:30 +-MRI Tuesday [**7-25**]-9:30am, [**Location (un) **] [**Hospital Ward Name 23**] Building +-[**Company 191**] [**Telephone/Fax (1) 250**] N.P-[**7-25**] 1:40pm +-Stroke center Dr. [**Last Name (STitle) **] at the [**Hospital Ward Name 23**] center, [**Location (un) **]-Tuesday [**8-1**], 5:00pm-you will need to call your PCP +for [**Name Initial (PRE) **] referral +-Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Company 191**] ([**Hospital Ward Name 23**] Building) Tuesday [**8-15**] 2:00pm + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2141-6-19**]",167,2141-06-11 10:17:00,2141-06-17 16:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE EMERGENCY," +a/p: 23 f with sle, esrd not on hd, chronic vte with rue and +facial swelling p/w hypertensive emergency and delta ms +initially admitted to the [**hospital unit name 153**]. + +in the [**hospital unit name 153**] she was on a labetalol gtt as well as home +medications. she had head imaging (mri) with following results; +on the flair sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. she was evaluated by neurology who +considered pres, though she did not seize. she was started on +keppra as she has had seizures before, and will follow up with +them. +. +# htn emergency. she has had multiple admissions in the past +with neurological involvement, hemolysis in the past. sbp >300 +in ed. her bp was lowered slowly with a labetolol gtt in the +icu. when it was stably below 180 she was transferred to the +medical floor on the [**hospital ward name 517**]. she was continued on +clonidine tp, po labetalol, aliskiren. i/o goal was even. her +bp remained between 120-170 before discharge, she no longer had +any headaches, or nausea. she was oriented times three. +aliskiren was not covered by masshealth, and a prior auth was +faxed over. a supply from the pharmacy was sought but +unavailable. she was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. she was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# delta ms. [**2-11**] to hypertension likely ischemic/hypertensive +changes on ct. aao times three, no focal neurological signs +currently. also likely component of osa although this seems +chronic. no seizures although has had them in the past. +neuro was consulted, and she was started on keppra for question +of pres, keppra for 6 weeks until f/u with neuro, has outpatient +mri appointment as well. they will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#uti-found on admission, was on cipro-will complete course of 5 +days +. +# vte. l brachiocephalic vte chronic with collaterals. also h/o +other vte [**2-11**] to lines in the past. currently on coumadin. inr +2.1 coumadin was held in [**hospital unit name 153**] for anticipation of procedures. +her coumadin was restarted, has vna set up and will be followed +by [**hospital3 **]. +. +# facial swelling. unclear etiology likely [**2-11**] to vte in rue +(brachiocephalic) vs. angioedema-pt now without swelling +. +# esrd. currently no on hd due to patient preference, awaiting +to start pd next week. since patient has refused hd there was an +attempt to correct lytes and acid base with medications. avoided +fluid overload with lasix, patient currently making urine. lytes +- see below. she will commence pd as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on monday. her +ace/[**last name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# metabolic acidosis/electrolytes abnormalities. ag 15 likely +[**2-11**] to uremia. k elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. she received +kayexalate 30 mg tid until k <5 +her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# sle. on prednisone chronically, likely needs pcp [**name9 (pre) **] at some +point --atovaquone to prevent hyperkalemia +continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# anemia-hct and plts dropped on this admission but now stable + +. +# hocm. avoid dehydration. currently on labetalol. +. +# ppx: systemically anticoagulated, getting kayexalate, ppi +# fen: electrolytes as above, no standing fluids i/os goal even. + +# access: 2x piv currently +# code: full +# dispo: home + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other encephalopathy; Chronic glomerulonephritis in diseases classified elsewhere; Urinary tract infection, site not specified; Acidosis; Unspecified iridocyclitis; Acquired hemolytic anemia, unspecified; Systemic lupus erythematosus; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Swelling, mass, or lump in head and neck; Hyperpotassemia; Lump or mass in breast; Thrombocytopenia, unspecified; Hypocalcemia; Disorders of phosphorus metabolism]" +109,126055.0,14798,2141-11-03,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",50,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,126055.0,14798,2141-11-03,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",40,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,126055.0,14798,2141-11-03,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",150,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,126055.0,14798,2141-11-03,15329,147469.0,2141-06-17,Discharge summary,"Admission Date: [**2141-6-11**] Discharge Date: [**2141-6-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +hypertensive urgency + +Major Surgical or Invasive Procedure: +arterial line + +History of Present Illness: +HPI: 23 F with h/o Lupus, ESRD not on HD (planned PD), labile +hypertension, RUE VTE on anticoagulation, recent facial swelling +who presents with hypertensive emergency. Patient developed +severe frontal HA last evenening, a/w nausea. BP was not [**Location (un) 1131**] +on home BP cuff. In the AM her HA was severe [**10-20**] a/w nausea +and vomiting yellow/green liquid and BP cuff again not able to +obtain BP. Patient was last seen by VNA this past Friday with BP +130/70. Patient denies any CP, shortness of breath, abd pain. +Her facial swelling is slightly worse today. She denies any +weakness, dizziness, difficulty with speach, no numbness or +tingling. She says that she is compliant with all of her +medications. She denies any GU/GI complaints despite +UA in ED. + +. +In the ED, VS: 98.2 92 SBP >300/P [**Telephone/Fax (3) 44541**]-131) 16 98 % RA. +Patient received zofran IV, Hydral IV, Labetalol 20 mg IV x 1, +Nipride gtt started. Kayexalate 30 mg x 1. Other po meds written +but patient did not take due to nausea. CT head showing no +hemorrhage but hypoattenuation in frontal area, which is change +from prior MRI in [**Month (only) **]. She is on coumadin for RUE VTE with +INR 2.1. Also with UTI in ED, started Cirpo x 1. Labs showing K +5.6 ECG with ?hyperacute T waves, otherwise no changes, given +kayexalate only. +. +Interval Hx: Patient was admitted [**2141-5-24**] to [**6-6**] with facial +swelling and hypertensive emergency requiring ICU care. She was +also admitted [**Date range (1) 43498**] with similar complaints. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 98.8 84 [**Telephone/Fax (2) 44542**]% RA +Gen: swollen face L>R, alert and cooperative, NAD, snoring when +asleep but easily arousable +Heent: OP clear, swollen eye lids L>R, Left eye retracted with +prosthesis, anicteric, OP moist +Neck: supple, no JVD elevation, no meningismus +CV: nl S1 S2, RRR, [**1-15**] SM +Lungs: CTAB +Abd: obese, soft, NT, ND, BS+ +Ext: dry, no c/c/e, diminished, +Neuro: Alert and oriented x 3, gets drowsy intermittently but +arousable, CN II-XII intact, strength 5/5 throughout, sensations +intact + + +Pertinent Results: +[**6-14**]: AXR:IMPRESSION: PD catheter with tip coiled in the pelvis. +[**6-11**]: IMPRESSION: 1. Areas of hypoattenuation in the high +bifrontal white matter, and subcortical hypoattenuation in the +left posterior temporal lobe with loss of [**Doctor Last Name 352**]-white +differentiation. These findings are new from MRI brain [**12-29**], [**2140**], and could represent areas of new edema with underlying +focal lesion or possibly areas of new infarcts. An MRI head +without and with Iv conrast is recommended for further +characterization. +2. No evidence of intracranial hemorrhage. + +[**6-11**]: PA AND LATERAL VIEWS OF THE CHEST: There has been an +interval increase in retrocardiac opacity obscuring the left +hemidiaphragm. The right lung and the left upper lung zone are +clear. The right costophrenic angle is slightly blunted, +suggesting a very small right pleural effusion. The heart is +slightly enlarged, but the cardiomediastinal silhouette is +unchanged. There is no hilar enlargement. Soft tissue and bony +structures are unremarkable. + +IMPRESSION: Interval increase in left basilar atelectasis with +pleural effusion. Superimposed pneumonia cannot be excluded. +Possible small right pleural effusion. + +[**6-11**]: MR [**Name13 (STitle) 430**]: INDINGS: In comparison with a prior CT of the +head, the previously described low attenuation areas in the +parietal regions appear with hyperintensity signal on the FLAIR +sequence, mildly hyperintense on the diffusion-weighted +sequence, and also slightly hyperintense on the corresponding +ADC maps, these findings are nonspecific and may represent +posterior reversible encephalopathic changes, please correlate +clinically. There is no evidence of acute hemorrhage, +hydrocephalus, or midline shift. A low-attenuation area is +identified on the right occipital region, likely consistent with +chronic deposits of hemosiderin, please correlate with the prior +MRI dated [**2140-12-28**]. + +IMPRESSION: Limited examination secondary to motion artifacts. +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. The prior low-attenuation area of the +right occipital lobe is unchanged and may represent chronic +deposits of hemosiderin. There is no evidence of hydrocephalus +or midline shifting. Followup with MRI of the head with and +without contrast under conscious sedation is recommended if +clinically warranted. + +Brief Hospital Course: +A/P: 23 F with SLE, ESRD not on HD, chronic VTE with RUE and +facial swelling p/w hypertensive emergency and delta MS +initially admitted to the [**Hospital Unit Name 153**]. + +In the [**Hospital Unit Name 153**] she was on a labetalol gtt as well as home +medications. She had head imaging (MRI) with following results; +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. She was evaluated by neurology who +considered PRES, though she did not seize. She was started on +keppra as she has had seizures before, and will follow up with +them. +. +# HTN Emergency. She has had multiple admissions in the past +with neurological involvement, hemolysis in the past. SBP >300 +in ED. Her BP was lowered slowly with a labetolol gtt in the +ICU. When it was stably below 180 she was transferred to the +medical floor on the [**Hospital Ward Name 517**]. She was continued on +clonidine TP, po labetalol, aliskiren. I/O goal was even. Her +BP remained between 120-170 before discharge, she no longer had +any headaches, or nausea. She was oriented times three. +Aliskiren was not covered by masshealth, and a prior auth was +faxed over. A supply from the pharmacy was sought but +unavailable. She was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. She was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# Delta MS. [**2-11**] to hypertension likely ischemic/hypertensive +changes on CT. AAO times three, no focal neurological signs +currently. Also likely component of OSA although this seems +chronic. No seizures although has had them in the past. +Neuro was consulted, and she was started on Keppra for question +of PRES, keppra for 6 weeks until f/u with neuro, has outpatient +MRI appointment as well. They will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#UTI-found on admission, was on Cipro-will complete course of 5 +days +. +# VTE. L Brachiocephalic VTE chronic with collaterals. Also h/o +other VTE [**2-11**] to lines in the past. Currently on coumadin. INR +2.1 coumadin was held in [**Hospital Unit Name 153**] for anticipation of procedures. +Her coumadin was restarted, has VNA set up and will be followed +by [**Hospital3 **]. +. +# Facial Swelling. Unclear etiology likely [**2-11**] to VTE in RUE +(brachiocephalic) vs. angioedema-pt now without swelling +. +# ESRD. Currently no on HD due to patient preference, awaiting +to start PD next week. Since patient has refused HD there was an +attempt to correct lytes and acid base with medications. Avoided +fluid overload with lasix, patient currently making urine. Lytes +- see below. She will commence PD as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on Monday. Her +ACE/[**Last Name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# Metabolic Acidosis/Electrolytes abnormalities. AG 15 likely +[**2-11**] to uremia. K elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. She received +kayexalate 30 mg tid until K <5 +Her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# SLE. On prednisone chronically, likely needs PCP [**Name9 (PRE) **] at some +point --Atovaquone to prevent hyperkalemia +Continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# Anemia-Hct and plts dropped on this admission but now stable + +. +# HOCM. Avoid dehydration. Currently on Labetalol. +. +# PPX: systemically anticoagulated, getting kayexalate, PPI +# FEN: Electrolytes as above, no standing fluids I/Os goal even. + +# Access: 2x PIV currently +# Code: Full +# Dispo: home + + +Medications on Admission: + Pantoprazole 40 mg daily +- Clonidine TP 0.3/24 hrs q wednesday +- Prednisone 10 mg daily (just decreased from 15 mg) +- Calcitriol 0.25 mcg daily +- Sodium bicarbonate 650 mg 2 tabs daily +- Vit D3 400 mg daily +- Vit D2 50,000 q wed, x 10 weeks +- Labetalol 300 mg po 3 tabs TID +- Nifedipine SR 90 mg [**Hospital1 **] +- Warfarin 2 mg daily +- Hydral 25 mg TID +- Lasix 40 mg [**Hospital1 **] (started friday) +- Benadryl 25 mg po prn +- Ativan 1 mg [**Hospital1 **] prn +- Colace 100 mg [**Hospital1 **] prn +- Morphine 15 mg po q 6 hrs x 14 days +- Diovan 320 mg daily +- Dilaudid prn + + +Discharge Medications: +1. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +on alternating days with 15mg. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed. +4. Levetiracetam 250 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*60 Capsule(s)* Refills:*2* +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +Disp:*60 Tablet(s)* Refills:*0* +7. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day): please take as directed when blood pressure is above +180. +Disp:*90 Tablet(s)* Refills:*2* +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +9. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +Disp:*405 Tablet(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO BID (2 times a day). +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) +as needed for hold for sbp < 130. +Disp:*10 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +14. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO TID +(3 times a day). +15. Outpatient Lab Work +for [**Known firstname **] [**Known lastname **] DOB [**2117-8-7**] +please check INR once a week and have results faxed to +[**Hospital3 **] at [**Hospital1 18**] phone-[**Telephone/Fax (1) 14650**], fax-[**Telephone/Fax (1) 44543**] +16. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO once a day: +hold for sbp<130. +Disp:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +-hypertensive emergency +-Lupus - [**2134**]. Diagnosed after she began to have swolen fingers, +a rash and painful joints. +-ESRD secodary to SLE - [**2135**]. Was initially on cytoxan, 1 dose +every 3 months for 2 years until began dialysis 3 times a week +in [**2137**] (T, Th, Sat). Now no longer on Hemodialysis, with +hyperkalemia/Hypocalcemia/Hyperphosphatemia/Elevated +PTH/Metabolic Acidosis; PD Catheter placed [**5-18**] +-h/o seizures, ICU admissions; h/o two intraparenchymal +hemorrhages that were thought due to the posterior reversible +leukoencephalopathy syndrome, associated with LE paresis in [**2140**] +that resolved +-Uveitis secondary to SLE - [**4-16**]; s/p surgery [**2-16**]; she had +blood cleared and cataract removed as well as glaucoma. +-HOCM - per Echo in [**2137**] +-Mulitple episodes of dialysis reactions +-Anemia +-H/O SVC thrombus [**10-16**] [**2-11**] catheter placement, was on coumadin +then stopped; Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], +[**9-/2140**]); Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]); Negative Beta-2 glycoprotein antibody ([**4-/2138**], +[**8-/2140**]) +-Facial and left breast swelling - attributed to angioedema vs +chronic L Brachiocephalic vein occlusion +-Thrombophilia ?????? likely related to SLE, h/o recurrent VTE +-Thrombocytopenia NOS +-TTP (got plasmapheresisis) versus malignant HTN +-History of left eye enucleation [**2139-4-20**] for fungal infection + + +Discharge Condition: +stable, afebrile, SBP 120's-170's + + +Discharge Instructions: +You were admitted with hypertensive emergency, your blood +pressure was extremely high. You had a head CT and MRI that +showed some changes concerning for PRES (posterior reversible +leukoencephalopathy syndrome), and neurology recommended +initiating Keppra. Your blood pressure was brought under +control in the intensive care unit and now you have a new +regimen of medications. In addition peritoneal dialysis was +attempted but there were difficulties with your catheter. This +will be further addressed by your outpatient nephrologist. You +will continue to have your INR drawn and sent to coumadin +clinic. +You should take all your medications as prescribed, you will be +taking the keppra until you follow up with a neurologist in +approximately 6 weeks. You will also be taking the Aliskiren +following discharge. You will be discharged on hydralazine +(which you will take three times daily EVERY DAY), as well as +when your blood pressure gets too high as follows; +if you blood pressure is above 180 please take an extra dose of +hydralazine, check your blood pressure in 10 minutes, if it is +still not take another dose and recheck your blood pressure in +another 10 minutes-if it is still elevated take another 25mg +hydralazine and recheck in 10 minutes-if it is still elevated +please call your doctor or go to the ER. +Continue taking your coumadin and having your INR sent to +coumadin clinic. +Please seek medication attention if you have any headaches, +chest pain, shortness of breath, dizzyness, nausea or any other +concerning symptoms. +Please follow up as outlined below. + +Followup Instructions: +-Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Name12 (NameIs) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2141-6-30**] +10:00 +-Your renal team will contact you regarding follow up-you should +call CB for home teaching. +-Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-7-12**] 10:30 +-MRI Tuesday [**7-25**]-9:30am, [**Location (un) **] [**Hospital Ward Name 23**] Building +-[**Company 191**] [**Telephone/Fax (1) 250**] N.P-[**7-25**] 1:40pm +-Stroke center Dr. [**Last Name (STitle) **] at the [**Hospital Ward Name 23**] center, [**Location (un) **]-Tuesday [**8-1**], 5:00pm-you will need to call your PCP +for [**Name Initial (PRE) **] referral +-Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Company 191**] ([**Hospital Ward Name 23**] Building) Tuesday [**8-15**] 2:00pm + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2141-6-19**]",139,2141-06-11 10:17:00,2141-06-17 16:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE EMERGENCY," +a/p: 23 f with sle, esrd not on hd, chronic vte with rue and +facial swelling p/w hypertensive emergency and delta ms +initially admitted to the [**hospital unit name 153**]. + +in the [**hospital unit name 153**] she was on a labetalol gtt as well as home +medications. she had head imaging (mri) with following results; +on the flair sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. she was evaluated by neurology who +considered pres, though she did not seize. she was started on +keppra as she has had seizures before, and will follow up with +them. +. +# htn emergency. she has had multiple admissions in the past +with neurological involvement, hemolysis in the past. sbp >300 +in ed. her bp was lowered slowly with a labetolol gtt in the +icu. when it was stably below 180 she was transferred to the +medical floor on the [**hospital ward name 517**]. she was continued on +clonidine tp, po labetalol, aliskiren. i/o goal was even. her +bp remained between 120-170 before discharge, she no longer had +any headaches, or nausea. she was oriented times three. +aliskiren was not covered by masshealth, and a prior auth was +faxed over. a supply from the pharmacy was sought but +unavailable. she was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. she was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# delta ms. [**2-11**] to hypertension likely ischemic/hypertensive +changes on ct. aao times three, no focal neurological signs +currently. also likely component of osa although this seems +chronic. no seizures although has had them in the past. +neuro was consulted, and she was started on keppra for question +of pres, keppra for 6 weeks until f/u with neuro, has outpatient +mri appointment as well. they will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#uti-found on admission, was on cipro-will complete course of 5 +days +. +# vte. l brachiocephalic vte chronic with collaterals. also h/o +other vte [**2-11**] to lines in the past. currently on coumadin. inr +2.1 coumadin was held in [**hospital unit name 153**] for anticipation of procedures. +her coumadin was restarted, has vna set up and will be followed +by [**hospital3 **]. +. +# facial swelling. unclear etiology likely [**2-11**] to vte in rue +(brachiocephalic) vs. angioedema-pt now without swelling +. +# esrd. currently no on hd due to patient preference, awaiting +to start pd next week. since patient has refused hd there was an +attempt to correct lytes and acid base with medications. avoided +fluid overload with lasix, patient currently making urine. lytes +- see below. she will commence pd as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on monday. her +ace/[**last name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# metabolic acidosis/electrolytes abnormalities. ag 15 likely +[**2-11**] to uremia. k elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. she received +kayexalate 30 mg tid until k <5 +her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# sle. on prednisone chronically, likely needs pcp [**name9 (pre) **] at some +point --atovaquone to prevent hyperkalemia +continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# anemia-hct and plts dropped on this admission but now stable + +. +# hocm. avoid dehydration. currently on labetalol. +. +# ppx: systemically anticoagulated, getting kayexalate, ppi +# fen: electrolytes as above, no standing fluids i/os goal even. + +# access: 2x piv currently +# code: full +# dispo: home + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other encephalopathy; Chronic glomerulonephritis in diseases classified elsewhere; Urinary tract infection, site not specified; Acidosis; Unspecified iridocyclitis; Acquired hemolytic anemia, unspecified; Systemic lupus erythematosus; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Swelling, mass, or lump in head and neck; Hyperpotassemia; Lump or mass in breast; Thrombocytopenia, unspecified; Hypocalcemia; Disorders of phosphorus metabolism]" +109,172335.0,14797,2141-09-24,15329,147469.0,2141-06-17,Discharge summary,"Admission Date: [**2141-6-11**] Discharge Date: [**2141-6-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +hypertensive urgency + +Major Surgical or Invasive Procedure: +arterial line + +History of Present Illness: +HPI: 23 F with h/o Lupus, ESRD not on HD (planned PD), labile +hypertension, RUE VTE on anticoagulation, recent facial swelling +who presents with hypertensive emergency. Patient developed +severe frontal HA last evenening, a/w nausea. BP was not [**Location (un) 1131**] +on home BP cuff. In the AM her HA was severe [**10-20**] a/w nausea +and vomiting yellow/green liquid and BP cuff again not able to +obtain BP. Patient was last seen by VNA this past Friday with BP +130/70. Patient denies any CP, shortness of breath, abd pain. +Her facial swelling is slightly worse today. She denies any +weakness, dizziness, difficulty with speach, no numbness or +tingling. She says that she is compliant with all of her +medications. She denies any GU/GI complaints despite +UA in ED. + +. +In the ED, VS: 98.2 92 SBP >300/P [**Telephone/Fax (3) 44541**]-131) 16 98 % RA. +Patient received zofran IV, Hydral IV, Labetalol 20 mg IV x 1, +Nipride gtt started. Kayexalate 30 mg x 1. Other po meds written +but patient did not take due to nausea. CT head showing no +hemorrhage but hypoattenuation in frontal area, which is change +from prior MRI in [**Month (only) **]. She is on coumadin for RUE VTE with +INR 2.1. Also with UTI in ED, started Cirpo x 1. Labs showing K +5.6 ECG with ?hyperacute T waves, otherwise no changes, given +kayexalate only. +. +Interval Hx: Patient was admitted [**2141-5-24**] to [**6-6**] with facial +swelling and hypertensive emergency requiring ICU care. She was +also admitted [**Date range (1) 43498**] with similar complaints. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 98.8 84 [**Telephone/Fax (2) 44542**]% RA +Gen: swollen face L>R, alert and cooperative, NAD, snoring when +asleep but easily arousable +Heent: OP clear, swollen eye lids L>R, Left eye retracted with +prosthesis, anicteric, OP moist +Neck: supple, no JVD elevation, no meningismus +CV: nl S1 S2, RRR, [**1-15**] SM +Lungs: CTAB +Abd: obese, soft, NT, ND, BS+ +Ext: dry, no c/c/e, diminished, +Neuro: Alert and oriented x 3, gets drowsy intermittently but +arousable, CN II-XII intact, strength 5/5 throughout, sensations +intact + + +Pertinent Results: +[**6-14**]: AXR:IMPRESSION: PD catheter with tip coiled in the pelvis. +[**6-11**]: IMPRESSION: 1. Areas of hypoattenuation in the high +bifrontal white matter, and subcortical hypoattenuation in the +left posterior temporal lobe with loss of [**Doctor Last Name 352**]-white +differentiation. These findings are new from MRI brain [**12-29**], [**2140**], and could represent areas of new edema with underlying +focal lesion or possibly areas of new infarcts. An MRI head +without and with Iv conrast is recommended for further +characterization. +2. No evidence of intracranial hemorrhage. + +[**6-11**]: PA AND LATERAL VIEWS OF THE CHEST: There has been an +interval increase in retrocardiac opacity obscuring the left +hemidiaphragm. The right lung and the left upper lung zone are +clear. The right costophrenic angle is slightly blunted, +suggesting a very small right pleural effusion. The heart is +slightly enlarged, but the cardiomediastinal silhouette is +unchanged. There is no hilar enlargement. Soft tissue and bony +structures are unremarkable. + +IMPRESSION: Interval increase in left basilar atelectasis with +pleural effusion. Superimposed pneumonia cannot be excluded. +Possible small right pleural effusion. + +[**6-11**]: MR [**Name13 (STitle) 430**]: INDINGS: In comparison with a prior CT of the +head, the previously described low attenuation areas in the +parietal regions appear with hyperintensity signal on the FLAIR +sequence, mildly hyperintense on the diffusion-weighted +sequence, and also slightly hyperintense on the corresponding +ADC maps, these findings are nonspecific and may represent +posterior reversible encephalopathic changes, please correlate +clinically. There is no evidence of acute hemorrhage, +hydrocephalus, or midline shift. A low-attenuation area is +identified on the right occipital region, likely consistent with +chronic deposits of hemosiderin, please correlate with the prior +MRI dated [**2140-12-28**]. + +IMPRESSION: Limited examination secondary to motion artifacts. +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. The prior low-attenuation area of the +right occipital lobe is unchanged and may represent chronic +deposits of hemosiderin. There is no evidence of hydrocephalus +or midline shifting. Followup with MRI of the head with and +without contrast under conscious sedation is recommended if +clinically warranted. + +Brief Hospital Course: +A/P: 23 F with SLE, ESRD not on HD, chronic VTE with RUE and +facial swelling p/w hypertensive emergency and delta MS +initially admitted to the [**Hospital Unit Name 153**]. + +In the [**Hospital Unit Name 153**] she was on a labetalol gtt as well as home +medications. She had head imaging (MRI) with following results; +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. She was evaluated by neurology who +considered PRES, though she did not seize. She was started on +keppra as she has had seizures before, and will follow up with +them. +. +# HTN Emergency. She has had multiple admissions in the past +with neurological involvement, hemolysis in the past. SBP >300 +in ED. Her BP was lowered slowly with a labetolol gtt in the +ICU. When it was stably below 180 she was transferred to the +medical floor on the [**Hospital Ward Name 517**]. She was continued on +clonidine TP, po labetalol, aliskiren. I/O goal was even. Her +BP remained between 120-170 before discharge, she no longer had +any headaches, or nausea. She was oriented times three. +Aliskiren was not covered by masshealth, and a prior auth was +faxed over. A supply from the pharmacy was sought but +unavailable. She was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. She was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# Delta MS. [**2-11**] to hypertension likely ischemic/hypertensive +changes on CT. AAO times three, no focal neurological signs +currently. Also likely component of OSA although this seems +chronic. No seizures although has had them in the past. +Neuro was consulted, and she was started on Keppra for question +of PRES, keppra for 6 weeks until f/u with neuro, has outpatient +MRI appointment as well. They will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#UTI-found on admission, was on Cipro-will complete course of 5 +days +. +# VTE. L Brachiocephalic VTE chronic with collaterals. Also h/o +other VTE [**2-11**] to lines in the past. Currently on coumadin. INR +2.1 coumadin was held in [**Hospital Unit Name 153**] for anticipation of procedures. +Her coumadin was restarted, has VNA set up and will be followed +by [**Hospital3 **]. +. +# Facial Swelling. Unclear etiology likely [**2-11**] to VTE in RUE +(brachiocephalic) vs. angioedema-pt now without swelling +. +# ESRD. Currently no on HD due to patient preference, awaiting +to start PD next week. Since patient has refused HD there was an +attempt to correct lytes and acid base with medications. Avoided +fluid overload with lasix, patient currently making urine. Lytes +- see below. She will commence PD as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on Monday. Her +ACE/[**Last Name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# Metabolic Acidosis/Electrolytes abnormalities. AG 15 likely +[**2-11**] to uremia. K elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. She received +kayexalate 30 mg tid until K <5 +Her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# SLE. On prednisone chronically, likely needs PCP [**Name9 (PRE) **] at some +point --Atovaquone to prevent hyperkalemia +Continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# Anemia-Hct and plts dropped on this admission but now stable + +. +# HOCM. Avoid dehydration. Currently on Labetalol. +. +# PPX: systemically anticoagulated, getting kayexalate, PPI +# FEN: Electrolytes as above, no standing fluids I/Os goal even. + +# Access: 2x PIV currently +# Code: Full +# Dispo: home + + +Medications on Admission: + Pantoprazole 40 mg daily +- Clonidine TP 0.3/24 hrs q wednesday +- Prednisone 10 mg daily (just decreased from 15 mg) +- Calcitriol 0.25 mcg daily +- Sodium bicarbonate 650 mg 2 tabs daily +- Vit D3 400 mg daily +- Vit D2 50,000 q wed, x 10 weeks +- Labetalol 300 mg po 3 tabs TID +- Nifedipine SR 90 mg [**Hospital1 **] +- Warfarin 2 mg daily +- Hydral 25 mg TID +- Lasix 40 mg [**Hospital1 **] (started friday) +- Benadryl 25 mg po prn +- Ativan 1 mg [**Hospital1 **] prn +- Colace 100 mg [**Hospital1 **] prn +- Morphine 15 mg po q 6 hrs x 14 days +- Diovan 320 mg daily +- Dilaudid prn + + +Discharge Medications: +1. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +on alternating days with 15mg. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed. +4. Levetiracetam 250 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*60 Capsule(s)* Refills:*2* +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +Disp:*60 Tablet(s)* Refills:*0* +7. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day): please take as directed when blood pressure is above +180. +Disp:*90 Tablet(s)* Refills:*2* +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +9. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +Disp:*405 Tablet(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO BID (2 times a day). +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) +as needed for hold for sbp < 130. +Disp:*10 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +14. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO TID +(3 times a day). +15. Outpatient Lab Work +for [**Known firstname **] [**Known lastname **] DOB [**2117-8-7**] +please check INR once a week and have results faxed to +[**Hospital3 **] at [**Hospital1 18**] phone-[**Telephone/Fax (1) 14650**], fax-[**Telephone/Fax (1) 44543**] +16. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO once a day: +hold for sbp<130. +Disp:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +-hypertensive emergency +-Lupus - [**2134**]. Diagnosed after she began to have swolen fingers, +a rash and painful joints. +-ESRD secodary to SLE - [**2135**]. Was initially on cytoxan, 1 dose +every 3 months for 2 years until began dialysis 3 times a week +in [**2137**] (T, Th, Sat). Now no longer on Hemodialysis, with +hyperkalemia/Hypocalcemia/Hyperphosphatemia/Elevated +PTH/Metabolic Acidosis; PD Catheter placed [**5-18**] +-h/o seizures, ICU admissions; h/o two intraparenchymal +hemorrhages that were thought due to the posterior reversible +leukoencephalopathy syndrome, associated with LE paresis in [**2140**] +that resolved +-Uveitis secondary to SLE - [**4-16**]; s/p surgery [**2-16**]; she had +blood cleared and cataract removed as well as glaucoma. +-HOCM - per Echo in [**2137**] +-Mulitple episodes of dialysis reactions +-Anemia +-H/O SVC thrombus [**10-16**] [**2-11**] catheter placement, was on coumadin +then stopped; Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], +[**9-/2140**]); Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]); Negative Beta-2 glycoprotein antibody ([**4-/2138**], +[**8-/2140**]) +-Facial and left breast swelling - attributed to angioedema vs +chronic L Brachiocephalic vein occlusion +-Thrombophilia ?????? likely related to SLE, h/o recurrent VTE +-Thrombocytopenia NOS +-TTP (got plasmapheresisis) versus malignant HTN +-History of left eye enucleation [**2139-4-20**] for fungal infection + + +Discharge Condition: +stable, afebrile, SBP 120's-170's + + +Discharge Instructions: +You were admitted with hypertensive emergency, your blood +pressure was extremely high. You had a head CT and MRI that +showed some changes concerning for PRES (posterior reversible +leukoencephalopathy syndrome), and neurology recommended +initiating Keppra. Your blood pressure was brought under +control in the intensive care unit and now you have a new +regimen of medications. In addition peritoneal dialysis was +attempted but there were difficulties with your catheter. This +will be further addressed by your outpatient nephrologist. You +will continue to have your INR drawn and sent to coumadin +clinic. +You should take all your medications as prescribed, you will be +taking the keppra until you follow up with a neurologist in +approximately 6 weeks. You will also be taking the Aliskiren +following discharge. You will be discharged on hydralazine +(which you will take three times daily EVERY DAY), as well as +when your blood pressure gets too high as follows; +if you blood pressure is above 180 please take an extra dose of +hydralazine, check your blood pressure in 10 minutes, if it is +still not take another dose and recheck your blood pressure in +another 10 minutes-if it is still elevated take another 25mg +hydralazine and recheck in 10 minutes-if it is still elevated +please call your doctor or go to the ER. +Continue taking your coumadin and having your INR sent to +coumadin clinic. +Please seek medication attention if you have any headaches, +chest pain, shortness of breath, dizzyness, nausea or any other +concerning symptoms. +Please follow up as outlined below. + +Followup Instructions: +-Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Name12 (NameIs) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2141-6-30**] +10:00 +-Your renal team will contact you regarding follow up-you should +call CB for home teaching. +-Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-7-12**] 10:30 +-MRI Tuesday [**7-25**]-9:30am, [**Location (un) **] [**Hospital Ward Name 23**] Building +-[**Company 191**] [**Telephone/Fax (1) 250**] N.P-[**7-25**] 1:40pm +-Stroke center Dr. [**Last Name (STitle) **] at the [**Hospital Ward Name 23**] center, [**Location (un) **]-Tuesday [**8-1**], 5:00pm-you will need to call your PCP +for [**Name Initial (PRE) **] referral +-Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Company 191**] ([**Hospital Ward Name 23**] Building) Tuesday [**8-15**] 2:00pm + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2141-6-19**]",99,2141-06-11 10:17:00,2141-06-17 16:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE EMERGENCY," +a/p: 23 f with sle, esrd not on hd, chronic vte with rue and +facial swelling p/w hypertensive emergency and delta ms +initially admitted to the [**hospital unit name 153**]. + +in the [**hospital unit name 153**] she was on a labetalol gtt as well as home +medications. she had head imaging (mri) with following results; +on the flair sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. she was evaluated by neurology who +considered pres, though she did not seize. she was started on +keppra as she has had seizures before, and will follow up with +them. +. +# htn emergency. she has had multiple admissions in the past +with neurological involvement, hemolysis in the past. sbp >300 +in ed. her bp was lowered slowly with a labetolol gtt in the +icu. when it was stably below 180 she was transferred to the +medical floor on the [**hospital ward name 517**]. she was continued on +clonidine tp, po labetalol, aliskiren. i/o goal was even. her +bp remained between 120-170 before discharge, she no longer had +any headaches, or nausea. she was oriented times three. +aliskiren was not covered by masshealth, and a prior auth was +faxed over. a supply from the pharmacy was sought but +unavailable. she was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. she was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# delta ms. [**2-11**] to hypertension likely ischemic/hypertensive +changes on ct. aao times three, no focal neurological signs +currently. also likely component of osa although this seems +chronic. no seizures although has had them in the past. +neuro was consulted, and she was started on keppra for question +of pres, keppra for 6 weeks until f/u with neuro, has outpatient +mri appointment as well. they will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#uti-found on admission, was on cipro-will complete course of 5 +days +. +# vte. l brachiocephalic vte chronic with collaterals. also h/o +other vte [**2-11**] to lines in the past. currently on coumadin. inr +2.1 coumadin was held in [**hospital unit name 153**] for anticipation of procedures. +her coumadin was restarted, has vna set up and will be followed +by [**hospital3 **]. +. +# facial swelling. unclear etiology likely [**2-11**] to vte in rue +(brachiocephalic) vs. angioedema-pt now without swelling +. +# esrd. currently no on hd due to patient preference, awaiting +to start pd next week. since patient has refused hd there was an +attempt to correct lytes and acid base with medications. avoided +fluid overload with lasix, patient currently making urine. lytes +- see below. she will commence pd as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on monday. her +ace/[**last name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# metabolic acidosis/electrolytes abnormalities. ag 15 likely +[**2-11**] to uremia. k elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. she received +kayexalate 30 mg tid until k <5 +her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# sle. on prednisone chronically, likely needs pcp [**name9 (pre) **] at some +point --atovaquone to prevent hyperkalemia +continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# anemia-hct and plts dropped on this admission but now stable + +. +# hocm. avoid dehydration. currently on labetalol. +. +# ppx: systemically anticoagulated, getting kayexalate, ppi +# fen: electrolytes as above, no standing fluids i/os goal even. + +# access: 2x piv currently +# code: full +# dispo: home + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other encephalopathy; Chronic glomerulonephritis in diseases classified elsewhere; Urinary tract infection, site not specified; Acidosis; Unspecified iridocyclitis; Acquired hemolytic anemia, unspecified; Systemic lupus erythematosus; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Swelling, mass, or lump in head and neck; Hyperpotassemia; Lump or mass in breast; Thrombocytopenia, unspecified; Hypocalcemia; Disorders of phosphorus metabolism]" +109,172335.0,14797,2141-09-24,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",10,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,172335.0,14797,2141-09-24,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",16,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,172335.0,14797,2141-09-24,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",110,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,161950.0,14800,2141-12-01,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",84,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,126055.0,14798,2141-11-03,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",56,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,161950.0,14800,2141-12-01,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",78,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,161950.0,14800,2141-12-01,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",68,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,161950.0,14800,2141-12-01,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",28,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,161950.0,14800,2141-12-01,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",8,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,161950.0,14800,2141-12-01,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",178,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,125288.0,14799,2141-11-23,15329,147469.0,2141-06-17,Discharge summary,"Admission Date: [**2141-6-11**] Discharge Date: [**2141-6-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +hypertensive urgency + +Major Surgical or Invasive Procedure: +arterial line + +History of Present Illness: +HPI: 23 F with h/o Lupus, ESRD not on HD (planned PD), labile +hypertension, RUE VTE on anticoagulation, recent facial swelling +who presents with hypertensive emergency. Patient developed +severe frontal HA last evenening, a/w nausea. BP was not [**Location (un) 1131**] +on home BP cuff. In the AM her HA was severe [**10-20**] a/w nausea +and vomiting yellow/green liquid and BP cuff again not able to +obtain BP. Patient was last seen by VNA this past Friday with BP +130/70. Patient denies any CP, shortness of breath, abd pain. +Her facial swelling is slightly worse today. She denies any +weakness, dizziness, difficulty with speach, no numbness or +tingling. She says that she is compliant with all of her +medications. She denies any GU/GI complaints despite +UA in ED. + +. +In the ED, VS: 98.2 92 SBP >300/P [**Telephone/Fax (3) 44541**]-131) 16 98 % RA. +Patient received zofran IV, Hydral IV, Labetalol 20 mg IV x 1, +Nipride gtt started. Kayexalate 30 mg x 1. Other po meds written +but patient did not take due to nausea. CT head showing no +hemorrhage but hypoattenuation in frontal area, which is change +from prior MRI in [**Month (only) **]. She is on coumadin for RUE VTE with +INR 2.1. Also with UTI in ED, started Cirpo x 1. Labs showing K +5.6 ECG with ?hyperacute T waves, otherwise no changes, given +kayexalate only. +. +Interval Hx: Patient was admitted [**2141-5-24**] to [**6-6**] with facial +swelling and hypertensive emergency requiring ICU care. She was +also admitted [**Date range (1) 43498**] with similar complaints. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 98.8 84 [**Telephone/Fax (2) 44542**]% RA +Gen: swollen face L>R, alert and cooperative, NAD, snoring when +asleep but easily arousable +Heent: OP clear, swollen eye lids L>R, Left eye retracted with +prosthesis, anicteric, OP moist +Neck: supple, no JVD elevation, no meningismus +CV: nl S1 S2, RRR, [**1-15**] SM +Lungs: CTAB +Abd: obese, soft, NT, ND, BS+ +Ext: dry, no c/c/e, diminished, +Neuro: Alert and oriented x 3, gets drowsy intermittently but +arousable, CN II-XII intact, strength 5/5 throughout, sensations +intact + + +Pertinent Results: +[**6-14**]: AXR:IMPRESSION: PD catheter with tip coiled in the pelvis. +[**6-11**]: IMPRESSION: 1. Areas of hypoattenuation in the high +bifrontal white matter, and subcortical hypoattenuation in the +left posterior temporal lobe with loss of [**Doctor Last Name 352**]-white +differentiation. These findings are new from MRI brain [**12-29**], [**2140**], and could represent areas of new edema with underlying +focal lesion or possibly areas of new infarcts. An MRI head +without and with Iv conrast is recommended for further +characterization. +2. No evidence of intracranial hemorrhage. + +[**6-11**]: PA AND LATERAL VIEWS OF THE CHEST: There has been an +interval increase in retrocardiac opacity obscuring the left +hemidiaphragm. The right lung and the left upper lung zone are +clear. The right costophrenic angle is slightly blunted, +suggesting a very small right pleural effusion. The heart is +slightly enlarged, but the cardiomediastinal silhouette is +unchanged. There is no hilar enlargement. Soft tissue and bony +structures are unremarkable. + +IMPRESSION: Interval increase in left basilar atelectasis with +pleural effusion. Superimposed pneumonia cannot be excluded. +Possible small right pleural effusion. + +[**6-11**]: MR [**Name13 (STitle) 430**]: INDINGS: In comparison with a prior CT of the +head, the previously described low attenuation areas in the +parietal regions appear with hyperintensity signal on the FLAIR +sequence, mildly hyperintense on the diffusion-weighted +sequence, and also slightly hyperintense on the corresponding +ADC maps, these findings are nonspecific and may represent +posterior reversible encephalopathic changes, please correlate +clinically. There is no evidence of acute hemorrhage, +hydrocephalus, or midline shift. A low-attenuation area is +identified on the right occipital region, likely consistent with +chronic deposits of hemosiderin, please correlate with the prior +MRI dated [**2140-12-28**]. + +IMPRESSION: Limited examination secondary to motion artifacts. +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. The prior low-attenuation area of the +right occipital lobe is unchanged and may represent chronic +deposits of hemosiderin. There is no evidence of hydrocephalus +or midline shifting. Followup with MRI of the head with and +without contrast under conscious sedation is recommended if +clinically warranted. + +Brief Hospital Course: +A/P: 23 F with SLE, ESRD not on HD, chronic VTE with RUE and +facial swelling p/w hypertensive emergency and delta MS +initially admitted to the [**Hospital Unit Name 153**]. + +In the [**Hospital Unit Name 153**] she was on a labetalol gtt as well as home +medications. She had head imaging (MRI) with following results; +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. She was evaluated by neurology who +considered PRES, though she did not seize. She was started on +keppra as she has had seizures before, and will follow up with +them. +. +# HTN Emergency. She has had multiple admissions in the past +with neurological involvement, hemolysis in the past. SBP >300 +in ED. Her BP was lowered slowly with a labetolol gtt in the +ICU. When it was stably below 180 she was transferred to the +medical floor on the [**Hospital Ward Name 517**]. She was continued on +clonidine TP, po labetalol, aliskiren. I/O goal was even. Her +BP remained between 120-170 before discharge, she no longer had +any headaches, or nausea. She was oriented times three. +Aliskiren was not covered by masshealth, and a prior auth was +faxed over. A supply from the pharmacy was sought but +unavailable. She was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. She was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# Delta MS. [**2-11**] to hypertension likely ischemic/hypertensive +changes on CT. AAO times three, no focal neurological signs +currently. Also likely component of OSA although this seems +chronic. No seizures although has had them in the past. +Neuro was consulted, and she was started on Keppra for question +of PRES, keppra for 6 weeks until f/u with neuro, has outpatient +MRI appointment as well. They will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#UTI-found on admission, was on Cipro-will complete course of 5 +days +. +# VTE. L Brachiocephalic VTE chronic with collaterals. Also h/o +other VTE [**2-11**] to lines in the past. Currently on coumadin. INR +2.1 coumadin was held in [**Hospital Unit Name 153**] for anticipation of procedures. +Her coumadin was restarted, has VNA set up and will be followed +by [**Hospital3 **]. +. +# Facial Swelling. Unclear etiology likely [**2-11**] to VTE in RUE +(brachiocephalic) vs. angioedema-pt now without swelling +. +# ESRD. Currently no on HD due to patient preference, awaiting +to start PD next week. Since patient has refused HD there was an +attempt to correct lytes and acid base with medications. Avoided +fluid overload with lasix, patient currently making urine. Lytes +- see below. She will commence PD as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on Monday. Her +ACE/[**Last Name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# Metabolic Acidosis/Electrolytes abnormalities. AG 15 likely +[**2-11**] to uremia. K elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. She received +kayexalate 30 mg tid until K <5 +Her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# SLE. On prednisone chronically, likely needs PCP [**Name9 (PRE) **] at some +point --Atovaquone to prevent hyperkalemia +Continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# Anemia-Hct and plts dropped on this admission but now stable + +. +# HOCM. Avoid dehydration. Currently on Labetalol. +. +# PPX: systemically anticoagulated, getting kayexalate, PPI +# FEN: Electrolytes as above, no standing fluids I/Os goal even. + +# Access: 2x PIV currently +# Code: Full +# Dispo: home + + +Medications on Admission: + Pantoprazole 40 mg daily +- Clonidine TP 0.3/24 hrs q wednesday +- Prednisone 10 mg daily (just decreased from 15 mg) +- Calcitriol 0.25 mcg daily +- Sodium bicarbonate 650 mg 2 tabs daily +- Vit D3 400 mg daily +- Vit D2 50,000 q wed, x 10 weeks +- Labetalol 300 mg po 3 tabs TID +- Nifedipine SR 90 mg [**Hospital1 **] +- Warfarin 2 mg daily +- Hydral 25 mg TID +- Lasix 40 mg [**Hospital1 **] (started friday) +- Benadryl 25 mg po prn +- Ativan 1 mg [**Hospital1 **] prn +- Colace 100 mg [**Hospital1 **] prn +- Morphine 15 mg po q 6 hrs x 14 days +- Diovan 320 mg daily +- Dilaudid prn + + +Discharge Medications: +1. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +on alternating days with 15mg. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed. +4. Levetiracetam 250 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*60 Capsule(s)* Refills:*2* +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +Disp:*60 Tablet(s)* Refills:*0* +7. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day): please take as directed when blood pressure is above +180. +Disp:*90 Tablet(s)* Refills:*2* +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +9. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +Disp:*405 Tablet(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO BID (2 times a day). +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) +as needed for hold for sbp < 130. +Disp:*10 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +14. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO TID +(3 times a day). +15. Outpatient Lab Work +for [**Known firstname **] [**Known lastname **] DOB [**2117-8-7**] +please check INR once a week and have results faxed to +[**Hospital3 **] at [**Hospital1 18**] phone-[**Telephone/Fax (1) 14650**], fax-[**Telephone/Fax (1) 44543**] +16. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO once a day: +hold for sbp<130. +Disp:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +-hypertensive emergency +-Lupus - [**2134**]. Diagnosed after she began to have swolen fingers, +a rash and painful joints. +-ESRD secodary to SLE - [**2135**]. Was initially on cytoxan, 1 dose +every 3 months for 2 years until began dialysis 3 times a week +in [**2137**] (T, Th, Sat). Now no longer on Hemodialysis, with +hyperkalemia/Hypocalcemia/Hyperphosphatemia/Elevated +PTH/Metabolic Acidosis; PD Catheter placed [**5-18**] +-h/o seizures, ICU admissions; h/o two intraparenchymal +hemorrhages that were thought due to the posterior reversible +leukoencephalopathy syndrome, associated with LE paresis in [**2140**] +that resolved +-Uveitis secondary to SLE - [**4-16**]; s/p surgery [**2-16**]; she had +blood cleared and cataract removed as well as glaucoma. +-HOCM - per Echo in [**2137**] +-Mulitple episodes of dialysis reactions +-Anemia +-H/O SVC thrombus [**10-16**] [**2-11**] catheter placement, was on coumadin +then stopped; Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], +[**9-/2140**]); Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]); Negative Beta-2 glycoprotein antibody ([**4-/2138**], +[**8-/2140**]) +-Facial and left breast swelling - attributed to angioedema vs +chronic L Brachiocephalic vein occlusion +-Thrombophilia ?????? likely related to SLE, h/o recurrent VTE +-Thrombocytopenia NOS +-TTP (got plasmapheresisis) versus malignant HTN +-History of left eye enucleation [**2139-4-20**] for fungal infection + + +Discharge Condition: +stable, afebrile, SBP 120's-170's + + +Discharge Instructions: +You were admitted with hypertensive emergency, your blood +pressure was extremely high. You had a head CT and MRI that +showed some changes concerning for PRES (posterior reversible +leukoencephalopathy syndrome), and neurology recommended +initiating Keppra. Your blood pressure was brought under +control in the intensive care unit and now you have a new +regimen of medications. In addition peritoneal dialysis was +attempted but there were difficulties with your catheter. This +will be further addressed by your outpatient nephrologist. You +will continue to have your INR drawn and sent to coumadin +clinic. +You should take all your medications as prescribed, you will be +taking the keppra until you follow up with a neurologist in +approximately 6 weeks. You will also be taking the Aliskiren +following discharge. You will be discharged on hydralazine +(which you will take three times daily EVERY DAY), as well as +when your blood pressure gets too high as follows; +if you blood pressure is above 180 please take an extra dose of +hydralazine, check your blood pressure in 10 minutes, if it is +still not take another dose and recheck your blood pressure in +another 10 minutes-if it is still elevated take another 25mg +hydralazine and recheck in 10 minutes-if it is still elevated +please call your doctor or go to the ER. +Continue taking your coumadin and having your INR sent to +coumadin clinic. +Please seek medication attention if you have any headaches, +chest pain, shortness of breath, dizzyness, nausea or any other +concerning symptoms. +Please follow up as outlined below. + +Followup Instructions: +-Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Name12 (NameIs) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2141-6-30**] +10:00 +-Your renal team will contact you regarding follow up-you should +call CB for home teaching. +-Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-7-12**] 10:30 +-MRI Tuesday [**7-25**]-9:30am, [**Location (un) **] [**Hospital Ward Name 23**] Building +-[**Company 191**] [**Telephone/Fax (1) 250**] N.P-[**7-25**] 1:40pm +-Stroke center Dr. [**Last Name (STitle) **] at the [**Hospital Ward Name 23**] center, [**Location (un) **]-Tuesday [**8-1**], 5:00pm-you will need to call your PCP +for [**Name Initial (PRE) **] referral +-Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Company 191**] ([**Hospital Ward Name 23**] Building) Tuesday [**8-15**] 2:00pm + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2141-6-19**]",159,2141-06-11 10:17:00,2141-06-17 16:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE EMERGENCY," +a/p: 23 f with sle, esrd not on hd, chronic vte with rue and +facial swelling p/w hypertensive emergency and delta ms +initially admitted to the [**hospital unit name 153**]. + +in the [**hospital unit name 153**] she was on a labetalol gtt as well as home +medications. she had head imaging (mri) with following results; +on the flair sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. she was evaluated by neurology who +considered pres, though she did not seize. she was started on +keppra as she has had seizures before, and will follow up with +them. +. +# htn emergency. she has had multiple admissions in the past +with neurological involvement, hemolysis in the past. sbp >300 +in ed. her bp was lowered slowly with a labetolol gtt in the +icu. when it was stably below 180 she was transferred to the +medical floor on the [**hospital ward name 517**]. she was continued on +clonidine tp, po labetalol, aliskiren. i/o goal was even. her +bp remained between 120-170 before discharge, she no longer had +any headaches, or nausea. she was oriented times three. +aliskiren was not covered by masshealth, and a prior auth was +faxed over. a supply from the pharmacy was sought but +unavailable. she was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. she was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# delta ms. [**2-11**] to hypertension likely ischemic/hypertensive +changes on ct. aao times three, no focal neurological signs +currently. also likely component of osa although this seems +chronic. no seizures although has had them in the past. +neuro was consulted, and she was started on keppra for question +of pres, keppra for 6 weeks until f/u with neuro, has outpatient +mri appointment as well. they will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#uti-found on admission, was on cipro-will complete course of 5 +days +. +# vte. l brachiocephalic vte chronic with collaterals. also h/o +other vte [**2-11**] to lines in the past. currently on coumadin. inr +2.1 coumadin was held in [**hospital unit name 153**] for anticipation of procedures. +her coumadin was restarted, has vna set up and will be followed +by [**hospital3 **]. +. +# facial swelling. unclear etiology likely [**2-11**] to vte in rue +(brachiocephalic) vs. angioedema-pt now without swelling +. +# esrd. currently no on hd due to patient preference, awaiting +to start pd next week. since patient has refused hd there was an +attempt to correct lytes and acid base with medications. avoided +fluid overload with lasix, patient currently making urine. lytes +- see below. she will commence pd as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on monday. her +ace/[**last name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# metabolic acidosis/electrolytes abnormalities. ag 15 likely +[**2-11**] to uremia. k elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. she received +kayexalate 30 mg tid until k <5 +her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# sle. on prednisone chronically, likely needs pcp [**name9 (pre) **] at some +point --atovaquone to prevent hyperkalemia +continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# anemia-hct and plts dropped on this admission but now stable + +. +# hocm. avoid dehydration. currently on labetalol. +. +# ppx: systemically anticoagulated, getting kayexalate, ppi +# fen: electrolytes as above, no standing fluids i/os goal even. + +# access: 2x piv currently +# code: full +# dispo: home + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other encephalopathy; Chronic glomerulonephritis in diseases classified elsewhere; Urinary tract infection, site not specified; Acidosis; Unspecified iridocyclitis; Acquired hemolytic anemia, unspecified; Systemic lupus erythematosus; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Swelling, mass, or lump in head and neck; Hyperpotassemia; Lump or mass in breast; Thrombocytopenia, unspecified; Hypocalcemia; Disorders of phosphorus metabolism]" +109,125288.0,14799,2141-11-23,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",70,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,125288.0,14799,2141-11-23,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",60,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,125288.0,14799,2141-11-23,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",20,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,125288.0,14799,2141-11-23,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",76,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,125288.0,14799,2141-11-23,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",170,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,137510.0,14810,2142-04-22,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",170,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,137510.0,14810,2142-04-22,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",150,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,137510.0,14810,2142-04-22,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",142,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,137510.0,14810,2142-04-22,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",129,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,137510.0,14810,2142-04-22,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",120,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,137510.0,14810,2142-04-22,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",100,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,137510.0,14810,2142-04-22,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",92,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,137510.0,14810,2142-04-22,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",89,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,137510.0,14810,2142-04-22,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",64,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,137510.0,14810,2142-04-22,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",30,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,137510.0,14810,2142-04-22,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",22,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,137510.0,14810,2142-04-22,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",55,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,124398.0,14809,2142-03-31,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",148,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,124398.0,14809,2142-03-31,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",128,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,124398.0,14809,2142-03-31,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",120,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,124398.0,14809,2142-03-31,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",107,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,124398.0,14809,2142-03-31,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",98,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,124398.0,14809,2142-03-31,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",78,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,124398.0,14809,2142-03-31,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",70,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,124398.0,14809,2142-03-31,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",67,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,124398.0,14809,2142-03-31,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",33,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,124398.0,14809,2142-03-31,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",8,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,124398.0,14809,2142-03-31,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",42,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,131345.0,15330,2141-09-08,15327,166018.0,2141-03-28,Discharge summary,"Admission Date: [**2141-3-27**] Discharge Date: [**2141-3-28**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Oxycodone Hcl/Acetaminophen + +Attending:[**First Name3 (LF) 3984**] +Chief Complaint: +Hypertensive urgency. + +Major Surgical or Invasive Procedure: +None. + +History of Present Illness: +Ms. [**Known lastname **] is a 23 year-old woman with a history of SLE and renal +failure secondary to lupus nephritis, off HD for one year, who +presents with elevated blood pressures. + +Patient was in her usual state of health when she presented to +her nephrologist today. At that time appoinment, her blood +pressure was noted to be 240/130. Other than mild nausea, the +patient did not have specific complaints. In particular, she +denied any headache, chest pains, shortness of breath, +palpatations, edema or decreased urine output. She reports +taking her blood pressure medications, as prescribed. Given the +severity of the hypertension, the patient was referred to the ED +for further evaluation. + +In the ED, initial blood pressure was 221/134 with a heart rate +of 84. With use of 600mg labetolol, 40mg lisinopril, one inch of +nitropaste, 50mg PO hydralazine, then a labetolol drip, the +blood pressures improved to 160-180 systolic and 90-110s +diastolic. + +Currently, the patient feels well other than some mild nausea. +She is somewhat lightheaded. Upon arrival, labetolol gtt and +nitro paste were still on with a SBP in the 140s. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +- ADAMTS 13 negative +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school and has not continued studies due to her +systemic lupus erythematosus. The patient is on disability, and +participates in focus groups. The patient does not drink alcohol +or smoke, and has never used recreational drugs. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +VITALS - T 97.4, BP 148/89, HR 90, RR 25, 100% on room air. +GENERAL: Well appearing thin female, in good spirits. Sitting up +in bed in no distress. +HEENT: Prosthesis of left eye. No icteris or palor. No carotid +bruits. +CARDIAC: Regular rate/rhythm. Harsh systolic murmur. Possible +decrease with clenched fists. +LUNG: Clear bilaterally with no rales/wheeze. +ABDOMEN: Soft. Non-tender. +EXT: Warm. No edema. +NEURO: Alert. Oriented x3. Cranial nerves intact (except left +eye extraocular muscles). Sensation intact grossly. +Finger-to-nose normal. Strength 5/5 in all extremities. +SKIN: No rash noted. Nail bed changes with mild pitting noted. + +Pertinent Results: +ADMISSION LABS: +=============== +C3: 61 +C4: 16 + +137 108 32 AGap=13 +------------ +4.4 20 6.2 + +Ca: 8.2 P: 5.2 +ALT: 15 AP: 216 Tbili: 0.3 Alb: 3.8 +AST: 41 TProt: 6.5 + +WBC: 3.4 +PLT: 93 +HCT: 26.5 +N:53.8 L:38.2 M:4.5 E:3.0 Bas:0.4 + +STUDIES: +======== +ECG ([**2141-3-27**]): NSR at 85. Normal axis. Normal intervals. LAA. +LVH. No new ST or T-wave changes. + +CHEST ([**2141-3-27**]): +1. Patchy retrocardiac opacity, new, which may simply represent +atelectasis. Early pneumonic infiltrate cannot be excluded. +2. No CHF. + +Brief Hospital Course: +23 y.o. F with lupus and renal failure [**2-11**] SLE, not on HD x 1 +year, HTN, and cardiomyopathy admitted with elevated BPs. + +# Hypertensive Urgency: This has been an ongoing issue for this +patient with prior admissions with hypertensive emergency +(seizures, intraparenchymal hemorrhages). In the ER, she was on +a labetalol drip and given nitropaste. On presentation to the +ICU, her blood pressure was below her baseline, and the +labetalol drip was stopped, and the nitropaste was removed. She +was transitioned to PO meds alone. Her labetalol was increased +to 900 mg TID. Nicardipine was increased to 60 mg [**Hospital1 **]. IV +hydralazine was used prn. Goal SBP 160-190 with DBP<110. Her +pressures remained in range during her stay, and she was +discharged on her home medications with instructions to increase +her labetalol to 900 TID. + +# ESRD: Secondary to lupus nephritis. Has been off HD for almost +one year. Currently, the plan is for living related donor +(mother). The work-up for this is in progress. There are no +plans for dialysis while awaiting transplant. Renal consult +followed patient throughout hospitalization and assisted with BP +control. She was continued on Vitamin D. + +# Thrombocytopenia: At baseline. + +# SLE: Continued prednisone. On discharge, she was instructed to +decrease her prednisone to 10 mg daily per renal. PCP [**Name9 (PRE) **] +should be addressed as an outpatient. + +# FEN: Repleted lytes prn, renal diet + +# PPX: Heparin SQ, bowel regimen, PPI + +# CODE: Full + +# DISPO: Home with close follow up with renal. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hour patchy weekly +2. Hydralazine 50 mg TID +3. Labetalol 600 mg TID +4. Nicardipine SR 60 mg daily +5. Lisinopril 40 mg po BID +6. Valsartan 320 mg po daily +7. Prednisone 15 mg po daily +8. Aranesp 40 mcg/0.4 mL syringe as directed every 2 weeks +9. Vitamin D2 50,000 unit capsule by mouth, one tablet per week +x 5 weeks, then one tablet per month x 5 months +10. Lorazepam po q4 - q6 hours prn (rarely uses) +11. Hydrocortisone 2.5% ointment to affected areas (not +currently using) +12. Tacrolimus 0.1% ointment to affected areas (not currently +using) + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWEEK (). +2. Hydralazine 25 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Nicardipine 60 mg Capsule, Sustained Release Sig: One (1) +Capsule, Sustained Release PO once a day. +4. Lisinopril 40 mg Tablet Sig: One (1) Tablet PO twice a day. +5. Valsartan 320 mg Tablet Sig: One (1) Tablet PO once a day. +6. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +Disp:*270 Tablet(s)* Refills:*2* +7. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +8. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO monthly (). +9. Aranesp (Polysorbate) 40 mcg/0.4 mL Syringe Sig: One (1) +injection Injection every 2 weeks: as directed by your doctor. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Hypertensive urgency + +Secondary Diagnosis: +1. End Stage Renal Disease +2. Thrombocytopenia +3. Lupus + + +Discharge Condition: +Stable. Ambulating. Tolerating po's. Afebrile. + + +Discharge Instructions: +You were admitted for hypertension urgency. You were treated +with IV medications and then transitioned to medications by +mouth. You were seen by the kidney doctors who helped [**Name5 (PTitle) **] manage +your hypertension. Your blood pressure is now under control. It +is very important that you take your medications as prescribed. +. +The following changes have been made to your medications: +1. Please decrease your prednisone dose to 10 mg daily. +2. Please increase labetalol 900 mg three times a day. +. +Please keep all your medical appointments. +. +If you have any of the following symptoms, please contact your +physician or go to the nearest ER: fever>101, chest pain, +shortness of breath, acute change of vision, abdominal pain, +persistent nausea and vomiting, or any other concerning +symptoms. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 2540**], RN Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-4-5**] 8:30 +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-4-10**] 1:00 +Provider: [**Name Initial (NameIs) 11595**] (RHEUM LMOB) [**Doctor Last Name 11596**] Phone:[**Telephone/Fax (1) 2226**] +Date/Time:[**2141-4-10**] 3:30 + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 2437**] MD [**MD Number(1) 2438**] + +Completed by:[**2141-3-28**]",164,2141-03-27 21:08:00,2141-03-28 17:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +23 y.o. f with lupus and renal failure [**2-11**] sle, not on hd x 1 +year, htn, and cardiomyopathy admitted with elevated bps. + +# hypertensive urgency: this has been an ongoing issue for this +patient with prior admissions with hypertensive emergency +(seizures, intraparenchymal hemorrhages). in the er, she was on +a labetalol drip and given nitropaste. on presentation to the +icu, her blood pressure was below her baseline, and the +labetalol drip was stopped, and the nitropaste was removed. she +was transitioned to po meds alone. her labetalol was increased +to 900 mg tid. nicardipine was increased to 60 mg [**hospital1 **]. iv +hydralazine was used prn. goal sbp 160-190 with dbp<110. her +pressures remained in range during her stay, and she was +discharged on her home medications with instructions to increase +her labetalol to 900 tid. + +# esrd: secondary to lupus nephritis. has been off hd for almost +one year. currently, the plan is for living related donor +(mother). the work-up for this is in progress. there are no +plans for dialysis while awaiting transplant. renal consult +followed patient throughout hospitalization and assisted with bp +control. she was continued on vitamin d. + +# thrombocytopenia: at baseline. + +# sle: continued prednisone. on discharge, she was instructed to +decrease her prednisone to 10 mg daily per renal. pcp [**name9 (pre) **] +should be addressed as an outpatient. + +# fen: repleted lytes prn, renal diet + +# ppx: heparin sq, bowel regimen, ppi + +# code: full + +# dispo: home with close follow up with renal. + + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia, unspecified; ; Other postprocedural status; Other states following surgery of eye and adnexa]" +109,131345.0,15330,2141-09-08,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",94,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,131345.0,15330,2141-09-08,15329,147469.0,2141-06-17,Discharge summary,"Admission Date: [**2141-6-11**] Discharge Date: [**2141-6-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +hypertensive urgency + +Major Surgical or Invasive Procedure: +arterial line + +History of Present Illness: +HPI: 23 F with h/o Lupus, ESRD not on HD (planned PD), labile +hypertension, RUE VTE on anticoagulation, recent facial swelling +who presents with hypertensive emergency. Patient developed +severe frontal HA last evenening, a/w nausea. BP was not [**Location (un) 1131**] +on home BP cuff. In the AM her HA was severe [**10-20**] a/w nausea +and vomiting yellow/green liquid and BP cuff again not able to +obtain BP. Patient was last seen by VNA this past Friday with BP +130/70. Patient denies any CP, shortness of breath, abd pain. +Her facial swelling is slightly worse today. She denies any +weakness, dizziness, difficulty with speach, no numbness or +tingling. She says that she is compliant with all of her +medications. She denies any GU/GI complaints despite +UA in ED. + +. +In the ED, VS: 98.2 92 SBP >300/P [**Telephone/Fax (3) 44541**]-131) 16 98 % RA. +Patient received zofran IV, Hydral IV, Labetalol 20 mg IV x 1, +Nipride gtt started. Kayexalate 30 mg x 1. Other po meds written +but patient did not take due to nausea. CT head showing no +hemorrhage but hypoattenuation in frontal area, which is change +from prior MRI in [**Month (only) **]. She is on coumadin for RUE VTE with +INR 2.1. Also with UTI in ED, started Cirpo x 1. Labs showing K +5.6 ECG with ?hyperacute T waves, otherwise no changes, given +kayexalate only. +. +Interval Hx: Patient was admitted [**2141-5-24**] to [**6-6**] with facial +swelling and hypertensive emergency requiring ICU care. She was +also admitted [**Date range (1) 43498**] with similar complaints. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 98.8 84 [**Telephone/Fax (2) 44542**]% RA +Gen: swollen face L>R, alert and cooperative, NAD, snoring when +asleep but easily arousable +Heent: OP clear, swollen eye lids L>R, Left eye retracted with +prosthesis, anicteric, OP moist +Neck: supple, no JVD elevation, no meningismus +CV: nl S1 S2, RRR, [**1-15**] SM +Lungs: CTAB +Abd: obese, soft, NT, ND, BS+ +Ext: dry, no c/c/e, diminished, +Neuro: Alert and oriented x 3, gets drowsy intermittently but +arousable, CN II-XII intact, strength 5/5 throughout, sensations +intact + + +Pertinent Results: +[**6-14**]: AXR:IMPRESSION: PD catheter with tip coiled in the pelvis. +[**6-11**]: IMPRESSION: 1. Areas of hypoattenuation in the high +bifrontal white matter, and subcortical hypoattenuation in the +left posterior temporal lobe with loss of [**Doctor Last Name 352**]-white +differentiation. These findings are new from MRI brain [**12-29**], [**2140**], and could represent areas of new edema with underlying +focal lesion or possibly areas of new infarcts. An MRI head +without and with Iv conrast is recommended for further +characterization. +2. No evidence of intracranial hemorrhage. + +[**6-11**]: PA AND LATERAL VIEWS OF THE CHEST: There has been an +interval increase in retrocardiac opacity obscuring the left +hemidiaphragm. The right lung and the left upper lung zone are +clear. The right costophrenic angle is slightly blunted, +suggesting a very small right pleural effusion. The heart is +slightly enlarged, but the cardiomediastinal silhouette is +unchanged. There is no hilar enlargement. Soft tissue and bony +structures are unremarkable. + +IMPRESSION: Interval increase in left basilar atelectasis with +pleural effusion. Superimposed pneumonia cannot be excluded. +Possible small right pleural effusion. + +[**6-11**]: MR [**Name13 (STitle) 430**]: INDINGS: In comparison with a prior CT of the +head, the previously described low attenuation areas in the +parietal regions appear with hyperintensity signal on the FLAIR +sequence, mildly hyperintense on the diffusion-weighted +sequence, and also slightly hyperintense on the corresponding +ADC maps, these findings are nonspecific and may represent +posterior reversible encephalopathic changes, please correlate +clinically. There is no evidence of acute hemorrhage, +hydrocephalus, or midline shift. A low-attenuation area is +identified on the right occipital region, likely consistent with +chronic deposits of hemosiderin, please correlate with the prior +MRI dated [**2140-12-28**]. + +IMPRESSION: Limited examination secondary to motion artifacts. +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. The prior low-attenuation area of the +right occipital lobe is unchanged and may represent chronic +deposits of hemosiderin. There is no evidence of hydrocephalus +or midline shifting. Followup with MRI of the head with and +without contrast under conscious sedation is recommended if +clinically warranted. + +Brief Hospital Course: +A/P: 23 F with SLE, ESRD not on HD, chronic VTE with RUE and +facial swelling p/w hypertensive emergency and delta MS +initially admitted to the [**Hospital Unit Name 153**]. + +In the [**Hospital Unit Name 153**] she was on a labetalol gtt as well as home +medications. She had head imaging (MRI) with following results; +On the FLAIR sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. She was evaluated by neurology who +considered PRES, though she did not seize. She was started on +keppra as she has had seizures before, and will follow up with +them. +. +# HTN Emergency. She has had multiple admissions in the past +with neurological involvement, hemolysis in the past. SBP >300 +in ED. Her BP was lowered slowly with a labetolol gtt in the +ICU. When it was stably below 180 she was transferred to the +medical floor on the [**Hospital Ward Name 517**]. She was continued on +clonidine TP, po labetalol, aliskiren. I/O goal was even. Her +BP remained between 120-170 before discharge, she no longer had +any headaches, or nausea. She was oriented times three. +Aliskiren was not covered by masshealth, and a prior auth was +faxed over. A supply from the pharmacy was sought but +unavailable. She was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. She was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# Delta MS. [**2-11**] to hypertension likely ischemic/hypertensive +changes on CT. AAO times three, no focal neurological signs +currently. Also likely component of OSA although this seems +chronic. No seizures although has had them in the past. +Neuro was consulted, and she was started on Keppra for question +of PRES, keppra for 6 weeks until f/u with neuro, has outpatient +MRI appointment as well. They will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#UTI-found on admission, was on Cipro-will complete course of 5 +days +. +# VTE. L Brachiocephalic VTE chronic with collaterals. Also h/o +other VTE [**2-11**] to lines in the past. Currently on coumadin. INR +2.1 coumadin was held in [**Hospital Unit Name 153**] for anticipation of procedures. +Her coumadin was restarted, has VNA set up and will be followed +by [**Hospital3 **]. +. +# Facial Swelling. Unclear etiology likely [**2-11**] to VTE in RUE +(brachiocephalic) vs. angioedema-pt now without swelling +. +# ESRD. Currently no on HD due to patient preference, awaiting +to start PD next week. Since patient has refused HD there was an +attempt to correct lytes and acid base with medications. Avoided +fluid overload with lasix, patient currently making urine. Lytes +- see below. She will commence PD as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on Monday. Her +ACE/[**Last Name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# Metabolic Acidosis/Electrolytes abnormalities. AG 15 likely +[**2-11**] to uremia. K elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. She received +kayexalate 30 mg tid until K <5 +Her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# SLE. On prednisone chronically, likely needs PCP [**Name9 (PRE) **] at some +point --Atovaquone to prevent hyperkalemia +Continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# Anemia-Hct and plts dropped on this admission but now stable + +. +# HOCM. Avoid dehydration. Currently on Labetalol. +. +# PPX: systemically anticoagulated, getting kayexalate, PPI +# FEN: Electrolytes as above, no standing fluids I/Os goal even. + +# Access: 2x PIV currently +# Code: Full +# Dispo: home + + +Medications on Admission: + Pantoprazole 40 mg daily +- Clonidine TP 0.3/24 hrs q wednesday +- Prednisone 10 mg daily (just decreased from 15 mg) +- Calcitriol 0.25 mcg daily +- Sodium bicarbonate 650 mg 2 tabs daily +- Vit D3 400 mg daily +- Vit D2 50,000 q wed, x 10 weeks +- Labetalol 300 mg po 3 tabs TID +- Nifedipine SR 90 mg [**Hospital1 **] +- Warfarin 2 mg daily +- Hydral 25 mg TID +- Lasix 40 mg [**Hospital1 **] (started friday) +- Benadryl 25 mg po prn +- Ativan 1 mg [**Hospital1 **] prn +- Colace 100 mg [**Hospital1 **] prn +- Morphine 15 mg po q 6 hrs x 14 days +- Diovan 320 mg daily +- Dilaudid prn + + +Discharge Medications: +1. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +on alternating days with 15mg. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed. +4. Levetiracetam 250 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*60 Capsule(s)* Refills:*2* +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +Disp:*60 Tablet(s)* Refills:*0* +7. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day): please take as directed when blood pressure is above +180. +Disp:*90 Tablet(s)* Refills:*2* +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +9. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +Disp:*405 Tablet(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO BID (2 times a day). +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) +as needed for hold for sbp < 130. +Disp:*10 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +14. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO TID +(3 times a day). +15. Outpatient Lab Work +for [**Known firstname **] [**Known lastname **] DOB [**2117-8-7**] +please check INR once a week and have results faxed to +[**Hospital3 **] at [**Hospital1 18**] phone-[**Telephone/Fax (1) 14650**], fax-[**Telephone/Fax (1) 44543**] +16. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO once a day: +hold for sbp<130. +Disp:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +-hypertensive emergency +-Lupus - [**2134**]. Diagnosed after she began to have swolen fingers, +a rash and painful joints. +-ESRD secodary to SLE - [**2135**]. Was initially on cytoxan, 1 dose +every 3 months for 2 years until began dialysis 3 times a week +in [**2137**] (T, Th, Sat). Now no longer on Hemodialysis, with +hyperkalemia/Hypocalcemia/Hyperphosphatemia/Elevated +PTH/Metabolic Acidosis; PD Catheter placed [**5-18**] +-h/o seizures, ICU admissions; h/o two intraparenchymal +hemorrhages that were thought due to the posterior reversible +leukoencephalopathy syndrome, associated with LE paresis in [**2140**] +that resolved +-Uveitis secondary to SLE - [**4-16**]; s/p surgery [**2-16**]; she had +blood cleared and cataract removed as well as glaucoma. +-HOCM - per Echo in [**2137**] +-Mulitple episodes of dialysis reactions +-Anemia +-H/O SVC thrombus [**10-16**] [**2-11**] catheter placement, was on coumadin +then stopped; Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], +[**9-/2140**]); Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]); Negative Beta-2 glycoprotein antibody ([**4-/2138**], +[**8-/2140**]) +-Facial and left breast swelling - attributed to angioedema vs +chronic L Brachiocephalic vein occlusion +-Thrombophilia ?????? likely related to SLE, h/o recurrent VTE +-Thrombocytopenia NOS +-TTP (got plasmapheresisis) versus malignant HTN +-History of left eye enucleation [**2139-4-20**] for fungal infection + + +Discharge Condition: +stable, afebrile, SBP 120's-170's + + +Discharge Instructions: +You were admitted with hypertensive emergency, your blood +pressure was extremely high. You had a head CT and MRI that +showed some changes concerning for PRES (posterior reversible +leukoencephalopathy syndrome), and neurology recommended +initiating Keppra. Your blood pressure was brought under +control in the intensive care unit and now you have a new +regimen of medications. In addition peritoneal dialysis was +attempted but there were difficulties with your catheter. This +will be further addressed by your outpatient nephrologist. You +will continue to have your INR drawn and sent to coumadin +clinic. +You should take all your medications as prescribed, you will be +taking the keppra until you follow up with a neurologist in +approximately 6 weeks. You will also be taking the Aliskiren +following discharge. You will be discharged on hydralazine +(which you will take three times daily EVERY DAY), as well as +when your blood pressure gets too high as follows; +if you blood pressure is above 180 please take an extra dose of +hydralazine, check your blood pressure in 10 minutes, if it is +still not take another dose and recheck your blood pressure in +another 10 minutes-if it is still elevated take another 25mg +hydralazine and recheck in 10 minutes-if it is still elevated +please call your doctor or go to the ER. +Continue taking your coumadin and having your INR sent to +coumadin clinic. +Please seek medication attention if you have any headaches, +chest pain, shortness of breath, dizzyness, nausea or any other +concerning symptoms. +Please follow up as outlined below. + +Followup Instructions: +-Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Name12 (NameIs) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2141-6-30**] +10:00 +-Your renal team will contact you regarding follow up-you should +call CB for home teaching. +-Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-7-12**] 10:30 +-MRI Tuesday [**7-25**]-9:30am, [**Location (un) **] [**Hospital Ward Name 23**] Building +-[**Company 191**] [**Telephone/Fax (1) 250**] N.P-[**7-25**] 1:40pm +-Stroke center Dr. [**Last Name (STitle) **] at the [**Hospital Ward Name 23**] center, [**Location (un) **]-Tuesday [**8-1**], 5:00pm-you will need to call your PCP +for [**Name Initial (PRE) **] referral +-Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Company 191**] ([**Hospital Ward Name 23**] Building) Tuesday [**8-15**] 2:00pm + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2141-6-19**]",83,2141-06-11 10:17:00,2141-06-17 16:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE EMERGENCY," +a/p: 23 f with sle, esrd not on hd, chronic vte with rue and +facial swelling p/w hypertensive emergency and delta ms +initially admitted to the [**hospital unit name 153**]. + +in the [**hospital unit name 153**] she was on a labetalol gtt as well as home +medications. she had head imaging (mri) with following results; +on the flair sequence, there is evidence of hyperintensity areas +in the parietal regions, left occipital lobe, which are +nonspecific and may represent possible posterior reversible +encephalopathic changes. she was evaluated by neurology who +considered pres, though she did not seize. she was started on +keppra as she has had seizures before, and will follow up with +them. +. +# htn emergency. she has had multiple admissions in the past +with neurological involvement, hemolysis in the past. sbp >300 +in ed. her bp was lowered slowly with a labetolol gtt in the +icu. when it was stably below 180 she was transferred to the +medical floor on the [**hospital ward name 517**]. she was continued on +clonidine tp, po labetalol, aliskiren. i/o goal was even. her +bp remained between 120-170 before discharge, she no longer had +any headaches, or nausea. she was oriented times three. +aliskiren was not covered by masshealth, and a prior auth was +faxed over. a supply from the pharmacy was sought but +unavailable. she was given a prescription for 5 pills to bridge +her to the time when the prior auth would have been approved in +order to facilitate her paying for the prescription. she was +also given hydralazine and instructed on how to take extra doses +when her blood pressure increased. + +. +# delta ms. [**2-11**] to hypertension likely ischemic/hypertensive +changes on ct. aao times three, no focal neurological signs +currently. also likely component of osa although this seems +chronic. no seizures although has had them in the past. +neuro was consulted, and she was started on keppra for question +of pres, keppra for 6 weeks until f/u with neuro, has outpatient +mri appointment as well. they will likely keep her on keppra +until the changes in her parietal regions have resolved. + +. +#uti-found on admission, was on cipro-will complete course of 5 +days +. +# vte. l brachiocephalic vte chronic with collaterals. also h/o +other vte [**2-11**] to lines in the past. currently on coumadin. inr +2.1 coumadin was held in [**hospital unit name 153**] for anticipation of procedures. +her coumadin was restarted, has vna set up and will be followed +by [**hospital3 **]. +. +# facial swelling. unclear etiology likely [**2-11**] to vte in rue +(brachiocephalic) vs. angioedema-pt now without swelling +. +# esrd. currently no on hd due to patient preference, awaiting +to start pd next week. since patient has refused hd there was an +attempt to correct lytes and acid base with medications. avoided +fluid overload with lasix, patient currently making urine. lytes +- see below. she will commence pd as an outpatient (had issues +yesterday with catheter flushing)-still not working-will try +laxatives to relieve loops of bowel possibly wrapped around +catheter and she will follow up with renal on monday. her +ace/[**last name (un) **] were held, renally dosed her meds, and phos binder was +administered. +. +# metabolic acidosis/electrolytes abnormalities. ag 15 likely +[**2-11**] to uremia. k elevated to 5.6-6.0 however has been elevated +in the past, likely some chronic hyerkalemia. she received +kayexalate 30 mg tid until k <5 +her electrolytes stabilized and she was continued on her home +regimen of sodium bicarb (650mg two tabs daily). + +. +# sle. on prednisone chronically, likely needs pcp [**name9 (pre) **] at some +point --atovaquone to prevent hyperkalemia +continued on prednisone 10mg (dropped from 15mg 2 weeks ago) +. +# anemia-hct and plts dropped on this admission but now stable + +. +# hocm. avoid dehydration. currently on labetalol. +. +# ppx: systemically anticoagulated, getting kayexalate, ppi +# fen: electrolytes as above, no standing fluids i/os goal even. + +# access: 2x piv currently +# code: full +# dispo: home + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other encephalopathy; Chronic glomerulonephritis in diseases classified elsewhere; Urinary tract infection, site not specified; Acidosis; Unspecified iridocyclitis; Acquired hemolytic anemia, unspecified; Systemic lupus erythematosus; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Swelling, mass, or lump in head and neck; Hyperpotassemia; Lump or mass in breast; Thrombocytopenia, unspecified; Hypocalcemia; Disorders of phosphorus metabolism]" +109,147469.0,15329,2141-06-17,15327,166018.0,2141-03-28,Discharge summary,"Admission Date: [**2141-3-27**] Discharge Date: [**2141-3-28**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Oxycodone Hcl/Acetaminophen + +Attending:[**First Name3 (LF) 3984**] +Chief Complaint: +Hypertensive urgency. + +Major Surgical or Invasive Procedure: +None. + +History of Present Illness: +Ms. [**Known lastname **] is a 23 year-old woman with a history of SLE and renal +failure secondary to lupus nephritis, off HD for one year, who +presents with elevated blood pressures. + +Patient was in her usual state of health when she presented to +her nephrologist today. At that time appoinment, her blood +pressure was noted to be 240/130. Other than mild nausea, the +patient did not have specific complaints. In particular, she +denied any headache, chest pains, shortness of breath, +palpatations, edema or decreased urine output. She reports +taking her blood pressure medications, as prescribed. Given the +severity of the hypertension, the patient was referred to the ED +for further evaluation. + +In the ED, initial blood pressure was 221/134 with a heart rate +of 84. With use of 600mg labetolol, 40mg lisinopril, one inch of +nitropaste, 50mg PO hydralazine, then a labetolol drip, the +blood pressures improved to 160-180 systolic and 90-110s +diastolic. + +Currently, the patient feels well other than some mild nausea. +She is somewhat lightheaded. Upon arrival, labetolol gtt and +nitro paste were still on with a SBP in the 140s. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +- ADAMTS 13 negative +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school and has not continued studies due to her +systemic lupus erythematosus. The patient is on disability, and +participates in focus groups. The patient does not drink alcohol +or smoke, and has never used recreational drugs. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +VITALS - T 97.4, BP 148/89, HR 90, RR 25, 100% on room air. +GENERAL: Well appearing thin female, in good spirits. Sitting up +in bed in no distress. +HEENT: Prosthesis of left eye. No icteris or palor. No carotid +bruits. +CARDIAC: Regular rate/rhythm. Harsh systolic murmur. Possible +decrease with clenched fists. +LUNG: Clear bilaterally with no rales/wheeze. +ABDOMEN: Soft. Non-tender. +EXT: Warm. No edema. +NEURO: Alert. Oriented x3. Cranial nerves intact (except left +eye extraocular muscles). Sensation intact grossly. +Finger-to-nose normal. Strength 5/5 in all extremities. +SKIN: No rash noted. Nail bed changes with mild pitting noted. + +Pertinent Results: +ADMISSION LABS: +=============== +C3: 61 +C4: 16 + +137 108 32 AGap=13 +------------ +4.4 20 6.2 + +Ca: 8.2 P: 5.2 +ALT: 15 AP: 216 Tbili: 0.3 Alb: 3.8 +AST: 41 TProt: 6.5 + +WBC: 3.4 +PLT: 93 +HCT: 26.5 +N:53.8 L:38.2 M:4.5 E:3.0 Bas:0.4 + +STUDIES: +======== +ECG ([**2141-3-27**]): NSR at 85. Normal axis. Normal intervals. LAA. +LVH. No new ST or T-wave changes. + +CHEST ([**2141-3-27**]): +1. Patchy retrocardiac opacity, new, which may simply represent +atelectasis. Early pneumonic infiltrate cannot be excluded. +2. No CHF. + +Brief Hospital Course: +23 y.o. F with lupus and renal failure [**2-11**] SLE, not on HD x 1 +year, HTN, and cardiomyopathy admitted with elevated BPs. + +# Hypertensive Urgency: This has been an ongoing issue for this +patient with prior admissions with hypertensive emergency +(seizures, intraparenchymal hemorrhages). In the ER, she was on +a labetalol drip and given nitropaste. On presentation to the +ICU, her blood pressure was below her baseline, and the +labetalol drip was stopped, and the nitropaste was removed. She +was transitioned to PO meds alone. Her labetalol was increased +to 900 mg TID. Nicardipine was increased to 60 mg [**Hospital1 **]. IV +hydralazine was used prn. Goal SBP 160-190 with DBP<110. Her +pressures remained in range during her stay, and she was +discharged on her home medications with instructions to increase +her labetalol to 900 TID. + +# ESRD: Secondary to lupus nephritis. Has been off HD for almost +one year. Currently, the plan is for living related donor +(mother). The work-up for this is in progress. There are no +plans for dialysis while awaiting transplant. Renal consult +followed patient throughout hospitalization and assisted with BP +control. She was continued on Vitamin D. + +# Thrombocytopenia: At baseline. + +# SLE: Continued prednisone. On discharge, she was instructed to +decrease her prednisone to 10 mg daily per renal. PCP [**Name9 (PRE) **] +should be addressed as an outpatient. + +# FEN: Repleted lytes prn, renal diet + +# PPX: Heparin SQ, bowel regimen, PPI + +# CODE: Full + +# DISPO: Home with close follow up with renal. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hour patchy weekly +2. Hydralazine 50 mg TID +3. Labetalol 600 mg TID +4. Nicardipine SR 60 mg daily +5. Lisinopril 40 mg po BID +6. Valsartan 320 mg po daily +7. Prednisone 15 mg po daily +8. Aranesp 40 mcg/0.4 mL syringe as directed every 2 weeks +9. Vitamin D2 50,000 unit capsule by mouth, one tablet per week +x 5 weeks, then one tablet per month x 5 months +10. Lorazepam po q4 - q6 hours prn (rarely uses) +11. Hydrocortisone 2.5% ointment to affected areas (not +currently using) +12. Tacrolimus 0.1% ointment to affected areas (not currently +using) + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWEEK (). +2. Hydralazine 25 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Nicardipine 60 mg Capsule, Sustained Release Sig: One (1) +Capsule, Sustained Release PO once a day. +4. Lisinopril 40 mg Tablet Sig: One (1) Tablet PO twice a day. +5. Valsartan 320 mg Tablet Sig: One (1) Tablet PO once a day. +6. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +Disp:*270 Tablet(s)* Refills:*2* +7. Prednisone 10 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +8. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO monthly (). +9. Aranesp (Polysorbate) 40 mcg/0.4 mL Syringe Sig: One (1) +injection Injection every 2 weeks: as directed by your doctor. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Hypertensive urgency + +Secondary Diagnosis: +1. End Stage Renal Disease +2. Thrombocytopenia +3. Lupus + + +Discharge Condition: +Stable. Ambulating. Tolerating po's. Afebrile. + + +Discharge Instructions: +You were admitted for hypertension urgency. You were treated +with IV medications and then transitioned to medications by +mouth. You were seen by the kidney doctors who helped [**Name5 (PTitle) **] manage +your hypertension. Your blood pressure is now under control. It +is very important that you take your medications as prescribed. +. +The following changes have been made to your medications: +1. Please decrease your prednisone dose to 10 mg daily. +2. Please increase labetalol 900 mg three times a day. +. +Please keep all your medical appointments. +. +If you have any of the following symptoms, please contact your +physician or go to the nearest ER: fever>101, chest pain, +shortness of breath, acute change of vision, abdominal pain, +persistent nausea and vomiting, or any other concerning +symptoms. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 2540**], RN Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-4-5**] 8:30 +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2141-4-10**] 1:00 +Provider: [**Name Initial (NameIs) 11595**] (RHEUM LMOB) [**Doctor Last Name 11596**] Phone:[**Telephone/Fax (1) 2226**] +Date/Time:[**2141-4-10**] 3:30 + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 2437**] MD [**MD Number(1) 2438**] + +Completed by:[**2141-3-28**]",81,2141-03-27 21:08:00,2141-03-28 17:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +23 y.o. f with lupus and renal failure [**2-11**] sle, not on hd x 1 +year, htn, and cardiomyopathy admitted with elevated bps. + +# hypertensive urgency: this has been an ongoing issue for this +patient with prior admissions with hypertensive emergency +(seizures, intraparenchymal hemorrhages). in the er, she was on +a labetalol drip and given nitropaste. on presentation to the +icu, her blood pressure was below her baseline, and the +labetalol drip was stopped, and the nitropaste was removed. she +was transitioned to po meds alone. her labetalol was increased +to 900 mg tid. nicardipine was increased to 60 mg [**hospital1 **]. iv +hydralazine was used prn. goal sbp 160-190 with dbp<110. her +pressures remained in range during her stay, and she was +discharged on her home medications with instructions to increase +her labetalol to 900 tid. + +# esrd: secondary to lupus nephritis. has been off hd for almost +one year. currently, the plan is for living related donor +(mother). the work-up for this is in progress. there are no +plans for dialysis while awaiting transplant. renal consult +followed patient throughout hospitalization and assisted with bp +control. she was continued on vitamin d. + +# thrombocytopenia: at baseline. + +# sle: continued prednisone. on discharge, she was instructed to +decrease her prednisone to 10 mg daily per renal. pcp [**name9 (pre) **] +should be addressed as an outpatient. + +# fen: repleted lytes prn, renal diet + +# ppx: heparin sq, bowel regimen, ppi + +# code: full + +# dispo: home with close follow up with renal. + + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia, unspecified; ; Other postprocedural status; Other states following surgery of eye and adnexa]" +109,147469.0,15329,2141-06-17,15328,170149.0,2141-06-06,Discharge summary,"Admission Date: [**2141-5-24**] Discharge Date: [**2141-6-6**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Face, Left arm and breast swelling + +Major Surgical or Invasive Procedure: +Intravenous Catheterization of SVC/IVC. + +History of Present Illness: +23 year old woman with ESRD, SLE, recently placed PD catheter +who presents with periorbital swelling and Hypertensive urgency. +Of note she was recently admitted for tongue swelling on +[**4-7**]. At that time she was treated with Solu-Medrol, +famotidine and Benadryl in the emergency room, which was +continued for a total of three doses on the floor. The swelling +improved throughout her stay. She had been on both an ACE, [**Last Name (un) **] +and DRI at home, which she has been taking for many years. +Patient states that the tongue swelling is most likely due to a +sardine allergy. However, she had recently added Dilaudid to her +medications following PD catheter placement, so allergy to +Dilaudid was also considered. The ACE, [**Last Name (un) **] and DRI were held on +the day of admission for ?angioedema but restarted on day of +discharge without incident so she was discharged on them. + +She returned to the ED [**5-24**] with acute onset bilateral eye +swelling since night of [**5-23**]. VS T 97.9 HR 78 BP 231/120 RR 20 +Sat 100% RA. She was given IV solumedrol 125iv, benadryl IV, and +pepcid. Her BP was noted to be 240's despite labetolol 900mg po, +then labetolol 20mg iv x2 so was started on labetolol gtt: +highest dose 2mg/min. This was stopped after 35 minutes, in +favor of nitro gtt. States compliant with meds at home. + +Patient was comfortable on admission to the MICU. Notes pain in +abdomen 7.5/10 related to PD catheter placement (has had since +then), improves with morphine. Also notes swelling in eyes/face +since last night (has had in the past but never this severe, +always goes away on its own). She feels whole body is swollen +slightly but no more upper extremities than lower. She denies +visual changes, HA, change in hearing/tinitus, congestion, sore +throat, cough, SOB, chest pain, palpitations, nausea, vomitting, +diarrhea. Has baseline constipation (takes stool softener), last +BM 2 days ago (normal), no melena, brbpr, diarrhea. No dysuria, +hematuria, change in uop, increase weight or size (clothes fit +the same), tingling, numbness, weakness, discoordination, rash, +joint pain, recent travel, ill contacts, exotic foods. She notes +episode of throat swelling over weekend resolved, seemed to be +related to sardine eating (not new for her). + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient +denies past or current alcohol, tobacco, or illicit drug use. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +ON ADMISSION: +VS: T 98.0 BP 187/120 HR 77 RR 17 Sat 100% on RA +GEN: NAD +HEENT: + periorbital edema, AT, NC, PERRLA, EOMI, no conjuctival +injection, anicteric, OP clear, MMM +Neck: supple, no LAD, no carotid bruits +CV: RRR, nl s1, s2, II/VI HSM at R/L USB, S4, no rub +PULM: CTAB, no w/r/r with good air movement throughout +ABD: soft, mildly tender at PD catheter, ND, + BS, no HSM +EXT: warm, dry, +2 distal pulses BL, no femoral bruits, trace +non-pitting edema +NEURO: alert & oriented, CN II-XII grossly intact, 5/5 strength +throughout. No sensory deficits to light touch appreciated. No +asterixis +PSYCH: appropriate affect + +ON [**6-6**]: +-General: AAOx3, in NAD. +-VS: Tc: 95.2, Tmax (24hrs): 97.8 BP: 172/98 (80/43, 240/110 on +[**5-30**]; 120/70, 218/120 over last 24 hrs), P: 80 (80, 98), RR: 16, +O2: 98% RA. +-HEENT: Head NC, AT. MMM. Face, Neck swollen: equal bilaterally. +-Neck: Supple, No JVD, No tracheal deviation. +-CV: RRR, S1,S2. Grade II/XII holosystolic murmur radiating to R +carotid. JVP not elevated. No S4. +-Lungs: CTAB, no w/r. +-Abdomen: +BS, soft, nontender. +-Extremities: Warm, no lower extremity edema. L arm appears +slightly less swollen than yesterday. Dorsalis pedis and radial +pulses strong bilaterally. No evidence of rashes, ulcers or +varicose veins. +-Breast: L breast still swollen relative to R, but diminished +from initial presentation of swelling. Skin no longer tense. + +Pertinent Results: + WBC-3.9* RBC-2.19* Hgb-6.6* Hct-20.4* MCV-93 MCH-30.3 MCHC-32.4 +RDW-19.7* Plt Ct-114* + - Neuts-52.8 Lymphs-39.9 Monos-5.0 Eos-2.0 Baso-0.2 +PT-20.5* PTT-89.9* INR(PT)-1.9* +Fibrino-268 +Thrombn-37.4*# +AT III-92 ProtCFn-65* ProtCAg-PND ProtSFn-68 +Glucose-105 UreaN-62* Creat-8.1* Na-139 K-4.5 Cl-109* HCO3-17* +ALT-14 AST-35 LD(LDH)-254* CK(CPK)-176* AlkPhos-137* +Amylase-277* TotBili-0.4 +Calcium-6.8* Phos-5.9* Mg-1.5* +Hapto-90 +Homocys-37.8* +PTH-1603* + +UA: Color Straw Appear Clear SpecGr 1.009 pH 6.0 Urobil Neg Bili +Neg Leuk Sm Bld Neg Nitr Neg Prot 30 Glu Neg Ket Neg RBC 0-2 WBC +[**11-30**] Bact Few Yeast None Epi 0-2 + +U Tox: Urine Opiates Pos;Urine Benzos, Barbs, Cocaine, Amphet, +Mthdne Negative; UCG: Negative + +STUDIES: +Portable CXR [**5-24**]: Small left pleural effusion with associated +atelectasis, although early pneumonia cannot be excluded. No +CHF. + +ECG [**5-24**]: NSR (87), nl axis and intervals, TWI V5-V6, no change +from [**5-20**]. + +MRA [**5-24**]: +1. Occlusion of the right internal jugular vein below the +mandible which communicates with external jugular and subclavian +vein. Appearance suggest chronic disease. +2. Patent SVC. +3. Patent but narrowed left internal jugular vein but left +brachiocephalic +vein not visualized (possibly from technique). +4. Bibasilar atelectasis + +US upper extremity [**5-26**]: +[**Doctor Last Name **]-scale, color and Doppler son[**Name (NI) 1417**] of the left IJ, +subclavian, +axillary, brachial, basilic, and cephalic veins were performed. +There is +normal flow, compression, and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the left arm. + +MRV Chest [**5-30**]: +1. Limited study which demonstrates a chronically occluded and +completely +atrophic left brachiocephalic vein. +2. Right internal jugular vein not identified, likely +chronically occluded. Left internal jugular vein is very +diminuitive as before. +3. Large right external jugular vein emptying into the +subclavian vein. + +Venogram [**5-31**]: +1. Occlusion of the left brachiocephalic vein at the junction of +the subclavian and internal jugular with extensive collateral +formation consistent with chronic obstruction. +2. Patent left brachial, axillary, subclavian, and distal +internal jugular +vein. +3. Unsuccessful attempt to recanalize the left brachiocephalic +vein using a catheter and guidewire technique. + +Brief Hospital Course: +Ms. [**Known lastname **] is a 23yo woman with a history of SLE, ESRD and HTN +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into L sided facial, L arm +and L breast swelling throughout her stay. + +# L facial/arm and breast swelling: Initially this presented +only as facial swellingand ACE and [**Last Name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. We then suspected possible venous +thrombus with occlusion leading to edema. US of upper left +extremity failed to show evidence of acute occlusion, but showed +R IJ occlusion consistent with prior studies. MRA could not +visualize the L brachiocephalic vein. Repeat MRV suggested +chronic occlusion of the L brachiocephalic vein. Venogram +performed on [**5-31**] showed extensive collateralization of the L +brachiocephalic vein with patent flow through these collaterals. +Intervention on the L brachiocephalic vein was attempted by IR, +but was unsuccessful. The primary team, renal team, [**Month/Year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the L brachiocephalic vein. For this reason, the patient was +placed on Heparin IV as a bridge to coumadin anticoagulation +with goal INR [**2-12**]. Per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. The patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, Beta-2 glycoprotein +and AT3 antibodies. Protein C and S levels were unremarkable. +Although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). Her INR will be followed first by Dr. [**Last Name (STitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**Company 191**]. It +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. This was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for INR testing and varying +her coumadin dose as directed. +. +# Hypertension: The patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. It +remains unclear why her blood pressure is so chronically labile. +The hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. The patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. We stopped her Ace and [**Last Name (un) **] as above. We +discharged her to home on a regimen that was reviewed with her +nephrologist, Dr. [**Last Name (STitle) 4883**]. She is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine CR 90mg po +bid, hydralazine 35mg po tid. These medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. She is discharged with home VNA for blood pressure +checks and assistance with meds. She has purchased a portable BP +cuff and will keep a BP diary to bring to subsequent +appointments as well. The importance of BP control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. Her goal SBP is 140-160 at this time. +. +# ESRD: The patient has ESRD due to lupus nephritis. PD catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. The renal team followed her +closely throughout her stay. She was treated for hypocalcemia as +well as hyperkalemia. Her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. She plans to start HD within 1-2 weeks of discharge. She +will call [**Doctor First Name 3040**] the PD nurse tomorrow to set up an appointment +to have her catheter flushed and to start PD. She will be +closely followed by Dr. [**Last Name (STitle) 4883**] at PD. + +# SLE: The patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. She has no symptoms of acute +SLE flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: The pt is noted to have an abnormal pap +and colpo two years ago with CIN 2 and high risk HPV. This has +never been repeated, as the patient failed to schedule +appointments and DNK others. We discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +The patient was discharged to home with a clear plan to call +[**Doctor First Name 3040**], the PD nurse on the day after discharge to set up an +appointment to have her PD catheter flushed later this week, as +well as to set a date to start her PD. She will see Dr. [**Last Name (STitle) 44539**] +in [**Hospital **] clinic within the next 1-2 weeks. She will have her blood +drawn for INR in two days and faxed to Dr. [**Last Name (STitle) 4883**], +subsequently this will be faxed to the [**Company 191**] coumadin clinic and +her dose will be adjusted for INR [**2-12**]. We have also given her +the phone number to call [**Company 191**] and establish care with a new PCP, +[**Name10 (NameIs) 3**] her old PCP has now graduated and her complex management +makes a PCP [**Name Initial (PRE) 44540**]. (Her PCP must be at [**Company 191**] for the [**Company 191**] +coumadin clinic to follow her as well.) Finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed CIN 2 with high +risk HPV and this has not been followed. + +The above plan and appoitnments were reviewed with the pt and +her mother extensively. [**Name2 (NI) **] medication hcanges were also +extensively reviewed. + +Medications on Admission: +Hydralazine 50 mg PO TID +Labetalol 900 mg PO TID +Nicardipine 60 mg Sustained Release PO once a day +Cinacalcet 30 mg PO DAILY: she is not sure if taking +Calcium Acetate 667 mg PO TID W/MEALS +Sodium Bicarbonate 1300 mg PO TID +Aliskiren 150 mg PO once a day (was never taking) +Pantoprazole 40 mg PO once a day +Valsartan 320mg PO DAILY +Lisinopril 40 mg PO bid +Clonidine 0.3 mg/24 hr Patch Weekly QSUN: not sure when last +placed +Prednisone 15 mg PO DAILY +Morphine 15 mg Tablet PO Q6H as needed +Ergocalciferol (Vitamin D2) 50,000 unit Capsule daily: states +not taking +Epo 4,000 units M/W/F: states not taking +colace + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +Disp:*4 Patch Weekly(s)* Refills:*2* +3. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +4. Calcitriol 0.25 mcg Capsule Sig: One (1) Capsule PO once a +day. +Disp:*30 Capsule(s)* Refills:*2* +5. Sodium Bicarbonate 650 mg Tablet Sig: Two (2) Tablet PO once +a day. +Disp:*60 Tablet(s)* Refills:*2* +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO qwednesday (): for 10 weeks. +Disp:*10 Capsule(s)* Refills:*0* +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*2* +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO twice a day. +Disp:*60 Tablet Sustained Release(s)* Refills:*2* +10. Warfarin 1 mg Tablet Sig: Two (2) Tablet PO once a day: dose +to be adjusted by coumadin clinic. +Disp:*120 Tablet(s)* Refills:*2* +11. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO three times +a day. +Disp:*90 Tablet(s)* Refills:*2* +12. Benadryl 25 mg Capsule Sig: One (1) Capsule PO every six (6) +hours as needed for itching. +Disp:*50 Capsule(s)* Refills:*0* +13. Ativan 1 mg Tablet Sig: One (1) Tablet PO twice a day as +needed for anxiety. +Disp:*60 Tablet(s)* Refills:*0* +14. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day as +needed for constipation. +Disp:*60 Capsule(s)* Refills:*0* +15. Morphine 15 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 14 days. +Disp:*56 Tablet(s)* Refills:*0* +16. Outpatient Lab Work +Please have blood drawn on Friday, [**6-9**] for PT/INR. Please have +result faxed to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you +to adjust your coumadin (also called warfarin) dose as needed. +17. Outpatient Lab Work +Please have blood drawn on Monday [**2141-6-12**] for PT/INR and twice +per week thereafter until told by coumadin clinic that you can +decrease lab draws. Please have result faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 3534**]. They will call you to adjust +your coumadin (also called warfarin) dose as needed. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnoses: +Malignant Hypertension (Hypertensive Urgency) +Acute Exacerbation of Chronic Left Brachiocephalic vein +occlusion +Anemia + +Secondary Diagnoses: +SLE +ESRD +Hypertrophic Cardiomyopathy +Thrombocytopenia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted and treated for an acute exacerbation of a +chronic left brachiocephalic vein occlusion (a chronically +obstructed large vein closed off entirely) and hypertensive +urgency (very high blood pressure). We attempted to remove the +clot in your left brachiocephalic vein, but were unable to do +so. You have been started on long-term Coumadin (also called +warfarin) therapy to prevent future blood clots and to allow +natural dissolution of your current blood clot. + +Please change your medicines to only those you are given here! +There were many changes and it is very important that you stick +to the medication list as you have large, life-threatening +swings in the blood pressure when not taking consistently. + +We also treated you for high potassium levels and anemia, and +low vitamin D and calcium levels, which are related to your +kidney failure. Please follow up with Dr. [**Last Name (STitle) 4883**] for long term +treatment. + +Please check your blood pressure three times per day and keep a +blood pressure diary to bring with you to all medical +appointments. + +Please have your blood drawn on Friday [**6-9**] for PT/INR and faxed +to Dr. [**Last Name (STitle) 4883**] at [**Telephone/Fax (1) 434**]. He will call you if needed to +adjust your coumadin (warfarin) dose. After that, please have +your blood drawn on Monday [**6-12**] for PT/INR and faxed to the [**Hospital1 18**] +coumadin clinic at [**Telephone/Fax (1) 434**]. They will follow you in a +regular way to adjust your coumadin dose as needed. + +MEDICINES FOR BLOOD PRESSURE: +LABETALOL 900mg three times per day (same as before) +HYDRALAZINE 25mg three times per day (lower dose than before) +CLONIDINE PATCH 0.3mg qWednesday (same as before) +NIFEDIPINE SR 90mg twice per day (new medicine!) +**stop taking your lisinopril, nicardipine, Diovan and +Aliskerin!** + +MEDICINES FOR RENAL FAILURE: +ERGOCALCIFEROL [**Numeric Identifier 1871**] units pill every Wednesday (same as before) +CHOLECALCIFEROL 400 units every day (new) +CALCITRIOL 0.25 mg every day (new) +SODIUM BICARBONATE 1300mg once per day (less often then before) +** stop taking your calcium acetate (phoslo), cinecalcet, and +epo injection (you'll get it at peritoneal dialysis only)** + +OTHER MEDICINES: +PANTOPRAZOLE 40mg every day (same as before) +PREDNISONE 15mg every day (same as before) +MORPHINE 15mg every 6 hrs if needed for pain (same as before) +ATIVAN 1mg as needed for anxiety (same as before) +BENADRYL 25mg every 6 hrs if needed for itch (new) +COLACE 100mg twice per day if needed for constipation(same as +before) + +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + +If you have increased swelling, fever greater than 101, +shortness of breath, chest pain, or if you at any time become +concerned about your health please contact Dr. [**Last Name (STitle) 4883**] or go to +the nearest ER. + + +Followup Instructions: +APPOINTMENTS: +**1. Be sure to call [**Doctor First Name 3040**] tomorrow for an appointment on +Friday to flush your dialysis catheter and start dialysis next +week! + +2. gynecology appointment: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Doctor Last Name **], Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2141-6-30**] 10:00AM + +3. nephrology appointment: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], Phone:[**Telephone/Fax (1) 435**] +Date/Time: [**2141-6-13**] 9:30AM + +**4. Please call [**Hospital3 **] next week to make an +appointment with a new primary doctor. I recommend Dr. +[**Last Name (STitle) 11009**], who is a resident who works with [**First Name8 (NamePattern2) 2426**] [**Last Name (NamePattern1) 2427**]. IT +IS VERY IMPORTANT THAT YOU KEEP THIS APPOINTMENT SO YOU CAN BE +FOLLOWED IN [**Hospital **] CLINIC. + +**5. Please have your blood drawn as above. Your coumadin level +will be followed by the [**Hospital 197**] clinic. Their phone # is +[**Telephone/Fax (1) 2173**]. Their fax # is [**Telephone/Fax (1) 3534**]. + + + +Completed by:[**2141-6-17**]",11,2141-05-24 14:47:00,2141-06-06 19:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ACUTE RENAL FAILURE," +ms. [**known lastname **] is a 23yo woman with a history of sle, esrd and htn +who presented with acute onset bilateral facial swelling and +hypertensive urgency, which developed into l sided facial, l arm +and l breast swelling throughout her stay. + +# l facial/arm and breast swelling: initially this presented +only as facial swellingand ace and [**last name (un) **] were held for possible +angioedema, however holding medications nad giving benadryl +failed to relieve symptoms. we then suspected possible venous +thrombus with occlusion leading to edema. us of upper left +extremity failed to show evidence of acute occlusion, but showed +r ij occlusion consistent with prior studies. mra could not +visualize the l brachiocephalic vein. repeat mrv suggested +chronic occlusion of the l brachiocephalic vein. venogram +performed on [**5-31**] showed extensive collateralization of the l +brachiocephalic vein with patent flow through these collaterals. +intervention on the l brachiocephalic vein was attempted by ir, +but was unsuccessful. the primary team, renal team, [**month/year (2) **] +team and hematology team suspect that the most likely etiology +of her swelling is an acute-on-chronic (now occlusive) thrombus +of the l brachiocephalic vein. for this reason, the patient was +placed on heparin iv as a bridge to coumadin anticoagulation +with goal inr [**2-12**]. per consult with hematology the patient is to +remain on this regimen for at least 6 months, and will then +revisit as an outpatient the question of possible lifelong +anticoagulation. the patient has had extensive negative testing +for hypercoagulable states, including during this work-up with +negative anticardiolipin, antiphospholipid, beta-2 glycoprotein +and at3 antibodies. protein c and s levels were unremarkable. +although her clots seem to have all occured in the setting of +lines, her continued thrombosis is likey due to +hypercoagulability from her lupus (in absence of lupus +anticoagulant). her inr will be followed first by dr. [**last name (stitle) 4883**], +her nephrologist, and then by the coumadin clinic of [**company 191**]. it +will be especially important that her coumadin be well titrated +given her risk of intracranial bleed with hypertension. this was +communicated tothe patient and she understands and plans to be +compliant with frequent blood draws for inr testing and varying +her coumadin dose as directed. +. +# hypertension: the patient has chronically labile hypertension, +with frequent episodes of hypertensive urgency over systolic +200, as well as lows as far as the 80s during this admission. it +remains unclear why her blood pressure is so chronically labile. +the hope is that once she starts dialysis this will help to +stabilize her blood pressure, however in the interim various +adjustments were made to her regimen. the patient received +frequent extra doses during her stay (especially of +hydralazine), however, this occasionally causes her blood +pressure to swing too low to tolerate her subsequent standing +dose of medication. we stopped her ace and [**last name (un) **] as above. we +discharged her to home on a regimen that was reviewed with her +nephrologist, dr. [**last name (stitle) 4883**]. she is discharged on clonidine +patch 0.3mg qweek, labetalol 900mg po tid, nifedipine cr 90mg po +bid, hydralazine 35mg po tid. these medications were reviewed +extensively with the patient and she was given prescriptions for +all meds. she is discharged with home vna for blood pressure +checks and assistance with meds. she has purchased a portable bp +cuff and will keep a bp diary to bring to subsequent +appointments as well. the importance of bp control, especially +in the setting of new anticoagulation, was discussed extensively +with the patient. her goal sbp is 140-160 at this time. +. +# esrd: the patient has esrd due to lupus nephritis. pd catheter +was placed before admission and the patient received morphine +prn pain at her catheter site. the renal team followed her +closely throughout her stay. she was treated for hypocalcemia as +well as hyperkalemia. her regimen was changed to calcitriol +0.25mcg po qday, sodium bicarb 1300mg po qday, cholecalciferol +400units po qday, ergocalciferol 50,000 units po qweek for ten +weeks. she plans to start hd within 1-2 weeks of discharge. she +will call [**doctor first name 3040**] the pd nurse tomorrow to set up an appointment +to have her catheter flushed and to start pd. she will be +closely followed by dr. [**last name (stitle) 4883**] at pd. + +# sle: the patient was maintained on her home dose of prednisone +15mg po qday throughout her stay. she has no symptoms of acute +sle flare, so her nephrologist and outpatient physicians may +attempt to wean this down as an outpatient. +. +# abnormal pap smear: the pt is noted to have an abnormal pap +and colpo two years ago with cin 2 and high risk hpv. this has +never been repeated, as the patient failed to schedule +appointments and dnk others. we discussed the importance of +following this up with the patient, and at her request scheduled +her for an ob/gyn appointment as an outpatient shortly after +discharge. + +the patient was discharged to home with a clear plan to call +[**doctor first name 3040**], the pd nurse on the day after discharge to set up an +appointment to have her pd catheter flushed later this week, as +well as to set a date to start her pd. she will see dr. [**last name (stitle) 44539**] +in [**hospital **] clinic within the next 1-2 weeks. she will have her blood +drawn for inr in two days and faxed to dr. [**last name (stitle) 4883**], +subsequently this will be faxed to the [**company 191**] coumadin clinic and +her dose will be adjusted for inr [**2-12**]. we have also given her +the phone number to call [**company 191**] and establish care with a new pcp, +[**name10 (nameis) 3**] her old pcp has now graduated and her complex management +makes a pcp [**name initial (pre) 44540**]. (her pcp must be at [**company 191**] for the [**company 191**] +coumadin clinic to follow her as well.) finally, the patient was +given an appointment with ob/gyn to have a follow up pap smear, +as her last pap and colpo two years ago showed cin 2 with high +risk hpv and this has not been followed. + +the above plan and appoitnments were reviewed with the pt and +her mother extensively. [**name2 (ni) **] medication hcanges were also +extensively reviewed. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Compression of vein; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Hyperpotassemia; Hyperparathyroidism, unspecified; Other iatrogenic hypotension; Nausea with vomiting; ; Abnormal glandular Papanicolaou smear of cervix; Abdominal pain, other specified site; Other specified disorders of pancreatic internal secretion; Adrenal cortical steroids causing adverse effects in therapeutic use]" +109,113189.0,14806,2142-02-17,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",156,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,113189.0,14806,2142-02-17,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",146,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,113189.0,14806,2142-02-17,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",106,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,113189.0,14806,2142-02-17,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",86,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,113189.0,14806,2142-02-17,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",78,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,113189.0,14806,2142-02-17,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",65,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,113189.0,14806,2142-02-17,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",56,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,113189.0,14806,2142-02-17,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",36,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,113189.0,14806,2142-02-17,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",28,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,113189.0,14806,2142-02-17,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",25,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,113189.0,14806,2142-02-17,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",162,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,176760.0,14805,2142-01-23,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",137,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,176760.0,14805,2142-01-23,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",131,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,176760.0,14805,2142-01-23,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",121,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,176760.0,14805,2142-01-23,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",81,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,176760.0,14805,2142-01-23,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",61,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,176760.0,14805,2142-01-23,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",53,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,176760.0,14805,2142-01-23,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",40,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,176760.0,14805,2142-01-23,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",31,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,176760.0,14805,2142-01-23,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",11,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,176760.0,14805,2142-01-23,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",3,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,158943.0,14808,2142-03-23,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",140,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,158943.0,14808,2142-03-23,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",120,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,158943.0,14808,2142-03-23,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",112,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,158943.0,14808,2142-03-23,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",99,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,158943.0,14808,2142-03-23,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",90,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,158943.0,14808,2142-03-23,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",70,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,158943.0,14808,2142-03-23,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",62,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,158943.0,14808,2142-03-23,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",59,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,158943.0,14808,2142-03-23,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",25,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,158943.0,14808,2142-03-23,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",34,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,158995.0,14807,2142-02-26,15330,131345.0,2141-09-08,Discharge summary,"Admission Date: [**2141-9-5**] Discharge Date: [**2141-9-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +right leg pain, hypertension + +Major Surgical or Invasive Procedure: +blood transfusion x2 + + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. The pain +is worst when she tried to bear weight on the leg, or when she +uses it to roll over or adjust her position in bed. The pain +begins in her buttock and travels down the posterior thigh and +calf but stops before reaching the ankle. It occasionally feels +like it is coming from her low back. She denies any +parasthesias or weakness in the leg, and she denies any numbness +in her foot or groin. She denies any fevers or incontinence. +The pain was unrelieved by Vicodin that she had at home, so she +scheduled an urgent visit with her nephrologist yesterday +[**2141-9-4**]. At her nephrologist??????s office, she was hypertensive to +250/145 and so she was referred to the ED. She ended up leaving +the ED against medical advice yesterday, but returned today +because of persistent leg pain. She reports that she took all +of her morning and noon BP meds. + + + +She denies any fevers, headaches, visual changes, nausea (prior +to coming to the ED), or leg weakness. + + + +Upon arrival to the ED today, she was afebrile, BP 237/146, HR +97, RR 16, Sat 100% on room air. She received a total of 90 mg +of IV labetalol and nitropaste, and was eventually put on a +labetalol drip for her hypertension. With these interventions, +her SBP dropped to the 180s, but she reported feeling nauseous +and so the drip was discontinued. She was also given 4 mg of IV +morphine and 1 mg of IV hydromorphone for her leg pain with +decent relief. Due to a urinalysis suggestive of infection, she +was given one tablet of DS TMP/SMX. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +to be due to the posterior reversible leukoencephalopathy +syndrome +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + +PAST SURGICAL HISTORY: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +MICU physical: +Tmax: 36.3 ??????C (97.4 ??????F) +Tcurrent: 36.3 ??????C (97.4 ??????F) +HR: 92 (92 - 94) bpm +BP: 209/138(152) {201/134(151) - 209/138(152)} mmHg +RR: 19 (19 - 30) insp/min +SpO2: 91% +Heart rhythm: SR (Sinus Rhythm) +Height: 59 Inch +General: well-appearing young woman in no acute distress +HEENT: no scleral icterus; prosthetic right eye +Neck: supple +Chest: clear to auscultation throughout, no +wheezes/rales/ronchi +CV: regular rate/rhythm, normal s1s2, no murmurs +Abdomen: soft, nontender, nondistended, PD catheter in place in +left abdomen +Back: very mild spinal tenderness over approx L3 level of spine +Extremities: no edema, 1+ PT pulses, warm +Skin: no rashes or jaundice +Neuro: alert, oriented x3, 5/5 strength in bilateral deltoids, +biceps, triceps, hip flexors/extensors, ankle flexors/extensors; +unable to elicit patellar reflexes bilaterally; negative +straight leg raise bilaterally + + +Pertinent Results: +138 111 54 +-----------------< 83 +5.4 14 8.2 +. +WBC: 3.7 +HCT: 19 +PLT: 101 +N:69.3 L:23.4 M:5.5 E:1.7 Bas:0.1 +PT: 21.9 PTT: 48.2 INR: 2.1 +. +Trends: +HCT: 19 -> 22 w 1u then received another unit. +INR 3.4 on discharge +Discharge chem: +Glucose-104 UreaN-51* Creat-8.4* Na-136 K-5.3* Cl-106 HCO3-18* +AnGap-17 +. +[**2141-9-8**] 07:30AM BLOOD CK(CPK)-126 +[**2141-9-5**] 02:50PM BLOOD HCG-<5 +. +[**2141-9-8**] 1:37 pm PERITONEAL FLUID + + GRAM STAIN (Final [**2141-9-8**]): + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count +. +MRI L-spine: +IMPRESSION: Diffuse low-signal intensity is identified in the +bone marrow of the lumbar and lower thoracic spine as described +above, possibly related with anemic changes, please correlate +clinically. There is no evidence of spinal canal stenosis or +neural foraminal narrowing at the different intervertebral disc +spaces. +. +CXR admit: IMPRESSION: Moderate cardiomegaly, bilateral pleural +effusions, and pulmonary vascular prominence consistent with +pulmonary edema. +. +Hip film: +FINDINGS: No comparisons. No acute fracture or dislocation is +seen. No +lucent or sclerotic lesion is noted. There is a distal aspect of +a catheter or shunt seen in the pelvis. Soft tissues are +otherwise unremarkable. There is minimal degenerative change of +the pubic symphysis. +IMPRESSION: No acute fracture or dislocation. +. +Abdominal film: +FINDINGS: A PD catheter is seen with its tip coiled in the +pelvis. There is normal bowel gas. The underlying osseous +structures are unremarkable. +IMPRESSION: PD catheter with tip coiled in the pelvis +. +CXR [**9-8**]: IMPRESSION: Marked cardiomegaly, unchanged. Interval +resolution of pulmonary edema. + + +Brief Hospital Course: +Ms [**Known lastname **] is a 24 year old woman with SLE, CKD V, and multiple +admissions for labile hypertension who presented to the ED +complaining of about a weeks?????? worth of right leg pain. She was +initially admitted to the MICU for hypertensive urgency and then +transfered to the floor after a day. + +# Hypertensive urgency: had been on labetalol drip in the ED, +but this was stopped due to nausea (presumed that her BP was +coming down too fast). She was started on her home meds and +tolerated these fairly well. Transferred to the floor and noted +to have SPBs in the 90s. She required 1L IVF bolus since her +baseline SBP is thought to run in the 130-170 range. She also +had transient dizziness during this episode. BP meds were held +and later that night her SBP was in the 220s. BP meds +restarted. She remained stable thereafter with SBPs in the +130-170s. We opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# Right leg pain: no evidence of avascular necrosis or fracture +on plain film. MRI and plain films were ordered and showed no +acute pathology. The pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. CK was normal. Pain was treated with dilaudid +initially. On day of discharge, she was able to ambulate +without gait abnormality or pain. PT saw her and rec outpt PT +followup. +. +# CKD V: PD catheter placement in place. Pt was tried on PD on a +number of occasions but did not tolerate it [**2-11**] pain. KUB +confirmed tip in place. Cx of peritoneal fluid not suggestive +of peritonitis. K remained mildly elevated. Hyperpara treated +with sevelamer (although patient refused) then tums. Pt will +reconsider PD as outpatient. +. +# Anemia: chronic. Received 2u pRBC while inhouse for Hct in +the 18-19 range. Had appropriate response. Not on Epo given +hypertension +. +# ID: Rx with cipro for ? UTI although urine cx neg. Also had +temp to 101 on evening prior to discharge. No clear source. PD +fluid cultured and NGTD. Pt remainded HD stable on day of +discharge. +. +# Prior SVC thrombus. Continued warfarin with appropriate INR +checks. INR elevated on day of discharge. Rec holding coumadin +for 2d +. +# Systemic lupus erythematosus: cont home prednisone dose +. +# Dispo status: ambulating, pain free, BP in the 150/90 range + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +Vicodin prn +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily + + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime. +3. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO DAILY (Daily). +4. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +5. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO WEEKLY (). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +Disp:*20 Capsule(s)* Refills:*0* +9. Outpatient Physical Therapy +Please provide PT for right hamstring injury +10. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +Disp:*270 Tablet(s)* Refills:*0* +11. Coumadin 2 mg Tablet Sig: One (1) Tablet PO at bedtime: hold +dose until [**9-10**]. +Disp:*30 Tablet(s)* Refills:*0* +12. Lactulose 10 gram/15 mL Solution Sig: 15-30 ml PO once a +day: goal is [**1-11**] soft bowel movements per day. +Disp:*500 ml* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +- HTN urgency +- right leg pain - thought [**2-11**] hamstring injury +- chronic kidney disease - not currently on dialysis +- SLE +- anemia [**2-11**] CKD and SLE +- hx of SVC thrombosis on coumadin now +Secondary: +- hx hypertrophic obstructive cardiomyopathy +- chronic thrombocytopenia + + +Discharge Condition: +ambulating without difficulty. tolerating oral diet. afebrile +and SBP in the 130-150 range. + + +Discharge Instructions: +You came in with right leg pain and poorly controlled +hypertension. Your blood pressure was controlled initially with +IV medications then your home medications. Since your blood +pressure was occasionally low, we recommend that you hold your +labetalol if you are feeling lightheaded or have dizziness or +have blood pressure less than 110/60. + +In terms of your leg pain, we performed xrays, ultrasound, and +MRI without finding a cause. We suspect a hamstring injury +given its location. Please take pain medications if needed. We +recommend followup with physical therapy. + +You also had a fever which is suggestive of infection. We +treated you with cipro in case you had a UTI. Otherwise, your +cultures were unrevealing. + +We attempted peritoneal dialysis but this was unsuccessful. +Please followup with your nephrologist. + +Please return to the ED if you experience headache, chest pain, +shortness of breath, high fevers, or worsening leg pain. + +Please hold your coumadin for two days then restart as per +previously written. Please take lactulose for constipation. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name11 (NameIs) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-9-12**] 5:00 +Provider: [**Name10 (NameIs) 706**] NURSE Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] +2:00 +Provider: [**Name10 (NameIs) 7548**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2141-9-14**] 3:00 + +Please followup with your nephrologist and PCP. [**Name10 (NameIs) **] would like +you to see your nephrologist within the next 1-2 weeks. + + + +",171,2141-09-05 20:04:00,2141-09-08 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +ms [**known lastname **] is a 24 year old woman with sle, ckd v, and multiple +admissions for labile hypertension who presented to the ed +complaining of about a weeks?????? worth of right leg pain. she was +initially admitted to the micu for hypertensive urgency and then +transfered to the floor after a day. + +# hypertensive urgency: had been on labetalol drip in the ed, +but this was stopped due to nausea (presumed that her bp was +coming down too fast). she was started on her home meds and +tolerated these fairly well. transferred to the floor and noted +to have spbs in the 90s. she required 1l ivf bolus since her +baseline sbp is thought to run in the 130-170 range. she also +had transient dizziness during this episode. bp meds were held +and later that night her sbp was in the 220s. bp meds +restarted. she remained stable thereafter with sbps in the +130-170s. we opted to discharge her on her home regimen +(without decreasing doses) since she is more often having issues +with elevated blood pressures. +. +# right leg pain: no evidence of avascular necrosis or fracture +on plain film. mri and plain films were ordered and showed no +acute pathology. the pain was in the distribution of her right +hamstring and was worsened when it was stretched thus suggesting +a muscle injury. ck was normal. pain was treated with dilaudid +initially. on day of discharge, she was able to ambulate +without gait abnormality or pain. pt saw her and rec outpt pt +followup. +. +# ckd v: pd catheter placement in place. pt was tried on pd on a +number of occasions but did not tolerate it [**2-11**] pain. kub +confirmed tip in place. cx of peritoneal fluid not suggestive +of peritonitis. k remained mildly elevated. hyperpara treated +with sevelamer (although patient refused) then tums. pt will +reconsider pd as outpatient. +. +# anemia: chronic. received 2u prbc while inhouse for hct in +the 18-19 range. had appropriate response. not on epo given +hypertension +. +# id: rx with cipro for ? uti although urine cx neg. also had +temp to 101 on evening prior to discharge. no clear source. pd +fluid cultured and ngtd. pt remainded hd stable on day of +discharge. +. +# prior svc thrombus. continued warfarin with appropriate inr +checks. inr elevated on day of discharge. rec holding coumadin +for 2d +. +# systemic lupus erythematosus: cont home prednisone dose +. +# dispo status: ambulating, pain free, bp in the 150/90 range + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Nausea alone; Other antihypertensive agents causing adverse effects in therapeutic use; Hip and thigh injury; Unspecified accident; Hypotension, unspecified; Anemia, unspecified; Personal history of venous thrombosis and embolism; End stage renal disease; ; Urinary tract infection, site not specified; Hyperpotassemia; Acidosis; Disorders of phosphorus metabolism; Hypocalcemia; Secondary hyperparathyroidism (of renal origin)]" +109,158995.0,14807,2142-02-26,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",165,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,158995.0,14807,2142-02-26,14797,172335.0,2141-09-24,Discharge summary,"Admission Date: [**2141-9-18**] Discharge Date: [**2141-9-24**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +hip pain + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +24yo woman with hx SLE, CKD(not currently on HD or PD), labile +HTN here with right leg pain and HTN urgency. Patient was +recently d/ced on [**9-14**] following admission for the same +complaints. +. +Patient took her hydralazine dose on am of admission. BP at +presentation to the ER was 250/140 (The patient reportedly has +baseline SBPs in 130-170s) She was given 900 labetolol and 50 +hydralazine in the ED. BP following this was 175/124. Her EKG +was unchanged. K was 5.7. +. +Patient also complaining of [**10-20**] right hip pain. Patient was +d/ced on [**9-14**] with oral dilaudid for hip/leg pain. She took this +only for one day due to severe itching. Denies any +parasthesias/weakness. Her RLE/hip pain has been extensively +worked up with negative LENIs, Lumbar spine MRI and hip plain +films in the past. She was given 4mg IV morphine in the ER. +. +On admission to the floor, leg/hip pain somwhat improved with +morphine.She denies any headache, vision changes, double vision, +chest pain or SOB. Feels warm but no chills. + + +Past Medical History: + Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter + +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of + +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the + +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant + +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). + +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 97.3 HR 81 BP 135/91 RR 16 100%RA +Gen:NAD, happy, pleasant female +HEENT:NC/AT, L eye prosthesis, R PERRL, EOMI, MMM, facial +swelling, L side>R, scerla anicteric +Neck: supple, no JVD, no LAD, scars from prior CVL and HD lines +CV:S1S2+, 2/6 SEM LUSB, loud P2, RRR, no ectopy +Pulm: CTA B/L, good inspiratory effort +Abd: +BS, soft, nontender, slightly distended and resonant to +percussion, PD catheter in place in left abdomen +ext: no c/c/e, 2+DP b/L, L foream swollen>R, R hip is mobile +without pain elicited on passive or active movement +neuro: AAOx3, nonfocal exam, CN 2-12 intact, moves all 4 +extremities +psych: mood/affect appropriate + + +Pertinent Results: +MRI Right Hip ([**9-18**]): There is no signal abnormality on the +fluid-sensitive +sequences in the proximal femur, acetabulum, or other osseous +structure. On T1- weighted images, there is a focal rounded +region within the right femoral head measuring approximately 9 +mm in a subchondral location, which is nonspecific but may +represent an unusual focus of red marrow. No sclerosis is seen +on the corresponding plain films. There is a small right hip +joint effusion and a small amount of fluid in the left hip joint +as well, at the upper limits of normal. There is no soft tissue +abnormality, no muscular edema, and no fluid collections. +IMPRESSION: 1. Small right hip joint effusion. 2. No bone marrow +edema in the proximal femurs or the pelvis. 3. Nonspecific small +focus of low signal on T1-weighted images in the right femoral +head is nonspecific but may represent an unusual focus of red +marrow. + +TTE ([**9-21**]): The left atrium is moderately dilated. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF 80%). A mild (18 mmHg) mid-cavitary gradient is +identified. Right ventricular chamber size and free wall motion +are normal. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic stenosis. The +increased transaortic velocity is likely related to high cardiac +output. Mild (1+) aortic regurgitation is seen. There is no +systolic anterior motion of the mitral valve leaflets. Mild (1+) +mitral regurgitation is seen. There is moderate pulmonary artery +systolic hypertension. There is a small pericardial effusion. +The effusion appears circumferential. There are no +echocardiographic signs of tamponade. +IMPRESSION: Severe symmetric left ventricular hypertrophy with +hyperdynamic systolic function and mild mid-cavitary gradient. +Mild aortic regurgitation. Moderate pulmonary hypertension. +Findings consistent with hyperrtophic cardiomyopathy. +Compared with the prior study (images reviewed) of [**2140-8-26**], +pulmonary hypertension has developed (also present on the study +from [**2140-5-20**]). Pericardial effusion is also new. + +V/Q scan ([**9-21**]): Ventilation images obtained with Tc-[**Age over 90 **]m aerosol +in 8 views demonstrate no focal defects with improved +ventilation to the posterior right basal segment. Perfusion +images in the same 8 views show improved perfusion to the +posterior right basal segement with a persistent small defect +but no new findings. +Chest x-ray shows cardiomgealy and left basilar atelectasis. +IMPRESSION: Improved V/Q scan from [**9-/2139**] with no findings to +suggest acute pulmonary embolism. + +B/L upper ext U/S ([**9-21**]): Grayscale and Doppler son[**Name (NI) 867**] of +the +right and left internal jugular, subclavian, axillary, brachial, +basilic and cephalic veins were performed. There is nonocclusive +focal thrombus seen in the left subclavian vein, where the vein +is not fully compressible. Flow is seen in the region, +indicating that the thrombus is nonocclusive. Elsewhere, normal +flow, augmentation, compressibility were appropriate and +waveforms are demonstrated. +IMPRESSION: +1. Focal nonocclusive thrombus in the left subclavian vein. +2. Otherwise, patent upper extremity veins as described. + +[**2141-9-18**] 02:15PM POTASSIUM-5.1 +[**2141-9-18**] 02:15PM HCT-21.2* +[**2141-9-18**] 08:45AM POTASSIUM-5.7* +[**2141-9-18**] 07:30AM GLUCOSE-88 UREA N-54* CREAT-8.6* SODIUM-136 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-15* ANION GAP-19 +[**2141-9-18**] 07:30AM estGFR-Using this +[**2141-9-18**] 07:30AM CALCIUM-7.3* PHOSPHATE-5.3* MAGNESIUM-1.6 +[**2141-9-18**] 07:30AM WBC-5.2 RBC-2.32* HGB-6.5* HCT-20.1* MCV-87 +MCH-28.1 MCHC-32.4 RDW-18.4* +[**2141-9-18**] 07:30AM NEUTS-78.0* LYMPHS-14.7* MONOS-3.9 EOS-3.2 +BASOS-0.3 +[**2141-9-18**] 07:30AM PLT COUNT-107* +[**2141-9-18**] 07:30AM PT-20.8* PTT-43.3* INR(PT)-2.0* +. +[**2141-9-21**] CXR: +There is no significant change when compared to the recent +previous +examination. +The previously described left retrocardiac opacity is unchanged +in appearance. +Cardiomegaly is also unchanged. The mediastinal contour, bony +thorax and +pulmonary vasculature are normal. +IMPRESSION: No significant change compared to study done roughly +7 hours +prior. + + +Brief Hospital Course: +24 yo with h/o of Lupus, HTN, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for R hip pain. Patient was on the floor on [**9-20**], +given morphine for the hip pain. She then had an episode of +hypotension and unresponsiveness and transferred to the MICU for +closer monitoring. The patient got 2L IVFs and narcan and +improved, in fact, found to be hypertensive upon arrival to +MICU. +. +MICU Course: On [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +Concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. Mental status cleared +somewhat with narcan. Renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. V/Q scan +demonstrated improvement since prior study. Patient's home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. She was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. PD fluid was not c/w SBP. CXR was +clear. Urine culture and blood cultures are pending. Patient's +BP was in the 110s so hydralazine was stopped. Her other BP meds +were otherwise continued. Plan was/is to follow renal recs for +PD. If, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. Would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. If patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. Would add neurontin 100mg TID with +room to titrate up to 300mg TID. Neuro also recommended PT with +TENS unit and referral to pain clinic although patient's pain is +currently absent. +. +FYI **** per Dr. [**Last Name (STitle) **] --- Because of ? increase in +cardiomegaly on CXR, she got an echo yesterday. In addition to +her known HOCM, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm Hg. They probably need to be followed up over +time (particularly the pulmonary hypertension). We did +evaluated the PHTN with a VQ scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +It would be good if we could arrange a PULMONARY CLINIC FOLLOW +UP for Ms. [**Known lastname **] after discharge with either [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] or [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **].**** + +. +She underwent CT head, and V/Q scan which were unremarkable. +Her steroid dose was increased to 15mg given concern for need +for stress dose steroids. After transfer from the MICU, her +steroids were dropped back to 5mg, her home dose with the +approval of [**Last Name (un) **]. +. +Her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. Her +hydralazine was discontinued. On day 2 of her MICU stay, she +developed a fever to 102. She was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +Broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. There was question of retrocardiac +opacity on CXR, though not clear. Rheum consult obtained given +hip discomfort, who felt septic joint unlikely. Neurology +consult obtained who felt autonomic seizure unlikely. +. +Pt initiated peritoneal dialysis. In this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising BPs. She is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. Her hip pain has resolved completely +without further intervention. +. +Floor course: +Fever: Spike fever in MICU to 102. Started on Levoquin, +Aztreonam, and Vanc. Source unclear at this point, but CXR with +question of retrocardiac opacity. There is a possibility of +aspiration pneumonitis. Other etiologies include peritoneal +fluid (PD cath), urine, and blood (though patient does not have +any indwelling lines). Hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. Peritoneal dialysis cultures negative so far. +Continued levo/vanco/aztreonam for 2 days empirically. Then +d/ced the Abx as no infectious etiologies were found. Steroids +back to home dosage. BCx, UCx (final neg), Peritoneal cultures +negative at discharge. +. +# Labile blood pressure: h/o of difficult to control BP with +episodes of hypertensive emergency in the past. Normal SBP runs +in 170s. Having nausea in setting of new PD, no evidence of +intracranial bleeding on clinical exam, though INR had been +supratherapeutic so remains in differential, though not +bradycardic. Continue home BP meds :Labetalol 900 mg PO TID but +difficult for patient to tolerate due to nausea, Aliskiren *NF* +150 mg Oral [**Hospital1 **], NIFEdipine CR 60 mg PO DAILY, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# Right leg/hip pain: no evidence of avascular necrosis or +fracture on MRI though there is a small effusion. Pain resolved +without intervention. Continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +Physical therapy to follow as an outpatient. [**Last Name (un) 18183**] followed. +Please see consult note. +. +# Hyperkalemia: Chronic issue. Patient takes kayexalate +intermittently per her report (last dose [**Last Name (un) 766**]). Monitored K +but patient did not need it on floor. + +# CKD V: Renal following. Did well with PD on [**9-22**] but did +report some nause and cramping. She was not tolerating all 1.5L +in exchanges on discharge. + +# Anemia: Hct stable around 20. S/p 1 U PRBCs in MICU with Hct +20.1 to 21.9. Likely due to chronic hemolysis consistent with +SLE> + +#. Prior SVC thrombus: Physical exam with L arm swelling +consistent with this. No flow limitations. INR 3.5 on ICU +admission. Held warfarin but restarted home 2mg daily the day +before discharge. + +# Systemic lupus erythematosus: Home prednisone dose 5mg. +Currently on 15mg in setting of acute illness (day 2). + +# General care: FEN: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, PD initiated, +Proph: INR therapeutic, no indication for PPI, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +Code: Full code, confirmed with patient Communication: with the +patient and her mother [**Name (NI) **] [**Name (NI) **], [**Telephone/Fax (2) 43497**]contact. Access: 2 +PIVs + + +Medications on Admission: +Nifedipine 60 mg PO qhs +Labetalol 900 mg PO tid +Hydralazine 50 mg PO tid +Clonidine 0.3 mg/hr patch qWED +Vitamin D once weekly +dilaudid PO prn +benadryl prn +lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 5 mg daily +coumadin 2mg PO qday +calcitriol 1 mcg daily + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +9. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO Q6H +(every 6 hours) as needed for itching. +10. Sodium Bicarbonate 650 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +12. Calcitriol 0.25 mcg Capsule Sig: Four (4) Capsule PO DAILY +(Daily). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: +Hypertensive urgency +Transient Hypotension due to Narcotics +Sciatica +. +Secondary: +End stage renal disease +Systemic Lupus Erythematosus +Anemia + + +Discharge Condition: +Stable. Blood pressures at baseline. Hip/leg pain resolved. +Ambulating without assistance. + + +Discharge Instructions: +You were admitted to the hospital with high blood pressure and +right leg/hip pain. We gave you pain medications and blood +pressure lowering medications. Your blood pressure then dropped +which was caused by the pain medication, and you were +transferred to the Intensive Care Unit(ICU) where you recovered +quickly. During your stay in the ICU, you developed a fever and +were started on antibiotics. However, the cultures that were +obtained were negative, and we discontinued the Antibiotics. +During your hospitalization, your blood pressure normalized on +your home regimen, and your right leg/hip pain resolved. You had +an MRI of your hip done, which did not show an acute infection. +You were seen by the kidney doctors and they recommended +starting peritoneal dialysis. You were also given some blood for +your anemia. + +Please follow up with the Peritoneal Dialysis nurse at the +scheduled day/time. Please make an appointment to meet with your +PCP in the next couple of weeks. + +Your Hip pain may benefit from physical therapy or outpatient +anesthetic joint injection. Please discuss these options with +your rheumatologist. +. +Please call the number given below to schedule outpatient +physical therapy. +. +Please restart your home medications. You were also started on +Sodium Bicarb 650mg by mouth three times a day. +. +If you develop fevers, chills, trouble breathing, chest pain, +worsening of hip pain, headaches, changes in your vision or any +other symptoms that concern you please return to the emergency +room or call your doctor. + +Followup Instructions: +Please follow up with your Peritoneal Dialysis nurse ([**Doctor First Name 3040**]) on +[**Doctor First Name 766**] [**2141-9-25**] +. +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2141-9-28**] 10:00 +. +Please call to schedule Outpatient Physical Therapy:[**Telephone/Fax (1) 2484**] + + + +Completed by:[**2141-9-25**]",155,2141-09-18 10:32:00,2141-09-24 13:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,LEG PAIN," +24 yo with h/o of lupus, htn, and lupus nephropathy started on +peitoneal dialysis during this admissionwho was admitted +initially for r hip pain. patient was on the floor on [**9-20**], +given morphine for the hip pain. she then had an episode of +hypotension and unresponsiveness and transferred to the micu for +closer monitoring. the patient got 2l ivfs and narcan and +improved, in fact, found to be hypertensive upon arrival to +micu. +. +micu course: on [**9-20**], the patient triggered for hypotension +(82/45), hypothermia (92.9) and altered mental status with +difficult arousability in setting of recent blood transfusion. +concern was for sepsis, autonomic seizure, transfusion reaction, +pulmonary embolus and/or narcosis. mental status cleared +somewhat with narcan. renal c/s felt episode likely [**2-11**] +accumulation of morphine active metabolites. v/q scan +demonstrated improvement since prior study. patients home +prednisone dose was increased from 5 to 15mg with thought that +patient may be stressed in setting of acute illness. she was +febrile on [**9-21**] and resultingly started in vancomycin, +aztreonam, and levofloxacin. pd fluid was not c/w sbp. cxr was +clear. urine culture and blood cultures are pending. patients +bp was in the 110s so hydralazine was stopped. her other bp meds +were otherwise continued. plan was/is to follow renal recs for +pd. if, in 24-48 hours (once cultures have had 48-72 hours to +grow) no source has been located, would d/c antibiotics except +for levofloxacin. would continue levoflox for total 5 day +course for pneumonia possibly ? aspiration pneumonitis during +episode of altered mental status. if patient has leg pain +again, may consider neurogenic source such a piriformis syndrome +as suggested by neurology. would add neurontin 100mg tid with +room to titrate up to 300mg tid. neuro also recommended pt with +tens unit and referral to pain clinic although patients pain is +currently absent. +. +fyi **** per dr. [**last name (stitle) **] --- because of ? increase in +cardiomegaly on cxr, she got an echo yesterday. in addition to +her known hocm, this showed (1) a small pericardial effusion, +and (2) pulmonary hypertension with an estimated tricuspid +gradient of 50 mm hg. they probably need to be followed up over +time (particularly the pulmonary hypertension). we did +evaluated the phtn with a vq scan which was unremarkable, making +chronic thromboembolic disease much lower on the differential. +it would be good if we could arrange a pulmonary clinic follow +up for ms. [**known lastname **] after discharge with either [**first name4 (namepattern1) **] [**last name (namepattern1) **] or [**first name4 (namepattern1) **] +[**last name (namepattern1) **].**** + +. +she underwent ct head, and v/q scan which were unremarkable. +her steroid dose was increased to 15mg given concern for need +for stress dose steroids. after transfer from the micu, her +steroids were dropped back to 5mg, her home dose with the +approval of [**last name (un) **]. +. +her hypotensive episode was thought to be due to a delayed +clearing of the morphine due to her renal failure. her +hydralazine was discontinued. on day 2 of her micu stay, she +developed a fever to 102. she was pan-cultured (blood, urine, +peritoneal dialysate) without obvious source of infection. +broad spectrum abx were started (vanco, cipro, aztreonam (pcn +allergy)) empirically. there was question of retrocardiac +opacity on cxr, though not clear. rheum consult obtained given +hip discomfort, who felt septic joint unlikely. neurology +consult obtained who felt autonomic seizure unlikely. +. +pt initiated peritoneal dialysis. in this setting she has been +having some nausea, which has made taking her home labetalol +difficult, resulting in some rising bps. she is called out to +medical service for ongoing management and workup of fever, +nausea, and hypertension. her hip pain has resolved completely +without further intervention. +. + +fever: spike fever in micu to 102. started on levoquin, +aztreonam, and vanc. source unclear at this point, but cxr with +question of retrocardiac opacity. there is a possibility of +aspiration pneumonitis. other etiologies include peritoneal +fluid (pd cath), urine, and blood (though patient does not have +any indwelling lines). hip, due to small effusion, could be +septic arthritis but no pain with movement on exam makes this +less likely. peritoneal dialysis cultures negative so far. +continued levo/vanco/aztreonam for 2 days empirically. then +d/ced the abx as no infectious etiologies were found. steroids +back to home dosage. bcx, ucx (final neg), peritoneal cultures +negative at discharge. +. +# labile blood pressure: h/o of difficult to control bp with +episodes of hypertensive emergency in the past. normal sbp runs +in 170s. having nausea in setting of new pd, no evidence of +intracranial bleeding on clinical exam, though inr had been +supratherapeutic so remains in differential, though not +bradycardic. continue home bp meds :labetalol 900 mg po tid but +difficult for patient to tolerate due to nausea, aliskiren *nf* +150 mg oral [**hospital1 **], nifedipine cr 60 mg po daily, clonidine patch, +hydralazine given hypertensive in setting of nausa. +. +# right leg/hip pain: no evidence of avascular necrosis or +fracture on mri though there is a small effusion. pain resolved +without intervention. continued to monitor +and would avoid narcotics, restart slowly if pain resumes. +physical therapy to follow as an outpatient. [**last name (un) 18183**] followed. +please see consult note. +. +# hyperkalemia: chronic issue. patient takes kayexalate +intermittently per her report (last dose [**last name (un) 766**]). monitored k +but patient did not need it on floor. + +# ckd v: renal following. did well with pd on [**9-22**] but did +report some nause and cramping. she was not tolerating all 1.5l +in exchanges on discharge. + +# anemia: hct stable around 20. s/p 1 u prbcs in micu with hct +20.1 to 21.9. likely due to chronic hemolysis consistent with +sle> + +#. prior svc thrombus: physical exam with l arm swelling +consistent with this. no flow limitations. inr 3.5 on icu +admission. held warfarin but restarted home 2mg daily the day +before discharge. + +# systemic lupus erythematosus: home prednisone dose 5mg. +currently on 15mg in setting of acute illness (day 2). + +# general care: fen: low sodium, renal diet; treatment of +hyperkalemia as above, replete other lytes prn, pd initiated, +proph: inr therapeutic, no indication for ppi, kayexalate as +needed for hyperkalemia and lactulose prn as per home regimen. +code: full code, confirmed with patient communication: with the +patient and her mother [**name (ni) **] [**name (ni) **], [**telephone/fax (2) 43497**]contact. access: 2 +pivs + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Pneumonia, organism unspecified; Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Hyperpotassemia; Sciatica; Other iatrogenic hypotension; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Anemia of other chronic disease; Hypocalcemia]" +109,158995.0,14807,2142-02-26,14798,126055.0,2141-11-03,Discharge summary,"Admission Date: [**2141-10-13**] Discharge Date: [**2141-11-3**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 6734**] +Chief Complaint: +Nausea, Vomitting, Abdominal Pain, HTN Urgenc + +Major Surgical or Invasive Procedure: +Upper GI endoscopy +Exploratory laparotomy +Tunneled hemodialysis catheter in R femoral vein +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y/o F with h/o ESRD, HTN who started +peritoneal dialysis during the week of [**2141-10-8**] and presented +with a 1 day history of acute onset N/V, sharp abdominal pain on +[**2141-10-13**]. (Of note, the patient had presented to the ED on +[**10-11**] with hypotension, SBPs in the 80s off after approximately +1.5L was taken off during dialysis in the setting of taking her +PO Anti-HTNs. On [**2141-10-11**] she received 0.5L IVF, labs WNL, and +was d/c'd home). On the day of admission on [**2141-10-13**], the +patient reported that the previous night, she was awoken from +sleep with severe, sharp abdominal pain, 6 episodes of frothy +emesis, 10+ yellowish BMs without melena or BRBRP.She was +admitted for further work- up of this abdminal pain. +. +In the ED here vitals were as follows: T: 97.0 HR: 101 BP: +240/180 RR: 17 O2sat: 100%RA. She received Labetolol 20mg IV +and was subsequently placed on a labetolol drip. She also +received ceftriaxone 1gm IV, Flagyl 500mg IV, Dilaudid 0.5-1mg +IV q1hr and Zofran. Her abdominal CT showed multifocal areas of +small bowel wall thickening. Her peritoneal Cell count was +negtaive for SBP. She had some signs of peritonitis and thus +surgery was consulted. Her lactate was normal. +. +Upon arrival to the MICU the patient was mentating well with +complaints of diffuse sharp abdominal pain that radiated to the +back and diarrhea. She had no headache or visual changes. + + +Past Medical History: +- SLE DX ([**2134**] - 16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous + +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +Placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). + +- Negative anticardiolipin antibodies IgG and IgM x4 +([**2137**]-[**2140**]). +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. + +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does + not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VITALS: 98.4 HR 98 192/131 21 100%RA +GEN: Mild Distress, AOx3 +HEENT: PEERLA, EOMI +NECK: Supple, No LAD, No bruit +RESP: CTAB +CARD: 2/6 systolic ejection murmur +ABD: soft, moderately tender with +/- guarding, BS+ +EXTR: Warm well perfused +NEURO: Motor Grossly Intact +RECTAL: Yellow Stool +BACK: B CVAT + + +Pertinent Results: +[**2141-11-3**] 08:50AM BLOOD WBC-3.5* RBC-2.55* Hgb-7.8* Hct-23.6* +MCV-92 MCH-30.6 MCHC-33.2 RDW-16.8* Plt Ct-176 +[**2141-11-3**] 03:55PM BLOOD PT-15.5* PTT-50.8* INR(PT)-1.4* +[**2141-11-3**] 08:50AM BLOOD Glucose-121* UreaN-33* Creat-5.2*# Na-140 +K-4.2 Cl-104 HCO3-28 AnGap-12 + +[**2141-10-26**] 06:15AM BLOOD ALT-11 AST-49* AlkPhos-122* Amylase-186* +TotBili-0.2 DirBili-0.1 IndBili-0.1 +[**2141-10-26**] 06:15AM BLOOD Lipase-30 +[**2141-11-3**] 08:50AM BLOOD Albumin-2.5* Calcium-7.8* Phos-4.1 Mg-1.9 +[**2141-10-30**] 06:55AM BLOOD HBsAg-NEGATIVE +[**2141-10-17**] 10:48AM BLOOD HBsAg-NEGATIVE HBsAb-POSITIVE +HBcAb-NEGATIVE HAV Ab-NEGATIVE IgM HBc-NEGATIVE IgM HAV-NEGATIVE +[**2141-10-25**] 11:56AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.014 +[**2141-10-25**] 11:56AM URINE Blood-TR Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2141-10-25**] 11:56AM URINE RBC-0-2 WBC-[**3-15**] Bacteri-FEW Yeast-NONE +Epi-21-50 + +Blood cultures: all negative + +EKG ([**2141-10-13**]): Sinus rhythm. Findings are within normal limits. +Compared to the previous tracing of [**2141-10-2**] there is no +significant diagnostic change. + +CXR ([**2141-10-13**]): No acute cardiopulmonary abnormality. No free +air under the diaphragms. + +CT chest/abdomen/pelvis ([**2141-10-13**]): There is a moderate-sized +pericardial +effusion, similar in appearance from [**2141-10-13**]. The great +vessels are normal in caliber, without aneurysmal dilatation. +Evaluation of the great vessels is limited without IV contrast. + +Interstitial thickening, particularly within the perihilar +regions, is +suggestive of fluid overload. There is bibasilar atelectasis +with a small +focus of consolidation in the right lower lobe (2:35) unchanged +from [**2141-10-13**], and may reflect aspiration or pneumonia. Scattered +bilateral nodules are largely stable from as far back as +[**2139-10-9**]. Specifically, there is a 5 mm nodule in the right +middle lobe (2:25), two adjacent nodules in the right lower lobe +measuring 5 mm and 2 mm (2:24), and a 4 mm pleural based nodule +within the left lower lobe. A nodular density seen adjacent and +anterior to the right main pulmonary artery (2:23) may reflect a +vessel. There is a small right pleural effusion. + +Axillary lymphadenopathy, with axillary nodes measuring up to +approximately 10 mm in short axis, is seen. Ill- defined soft +tissue thickening within the hilus bilaterally may reflect hilar +lymphadenopathy, but assessment is limited without IV contrast. +A catheter is visualized within the visualized right upper +extremity, which may reflect a PICC line that terminates within +the right subclavian vein. + +The esophagus is distended and filled with contrast, with marked +wall +thickening and edema throughout its entire length, a new +finding. There is a moderate- sized hiatal hernia. + +CT OF THE ABDOMEN WITHOUT IV CONTRAST: There has been interval +development of a moderate amount of free intraperitoneal air, +that layers anteriorly and along the anterior abdominal wall. +Additional small clustered foci of extraluminal air is seen +adjacent to the proximal stomach and the gastroesophageal +junction, with a focus of air tracking into the fissure of +ligamentum venosum. Additionally, there appears to be air +tracking into the anterior subcutaneous tissues in the region of +the umbilicus. These findings are all new from the prior CT on +[**2141-10-13**], but free air was present on chest radiograph performed +[**2141-10-25**]. There is no obvious evidence of extravasation of oral +contrast into the peritoneum. Of note, a peritoneal dialysis +catheter is in place that could represent a route of entry of +intraperitoneal air. + +The stomach, small bowel, and colon are filled with contrast, +without evidence of obstruction. Evaluation for wall thickening +is limited without IV contrast. + +Limited non-contrast views of the liver demonstrates a rounded +1.6 cm x 1.2 cm hypodensity in the right lobe of the liver, +previously characterized as a hemangioma. The liver is otherwise +unremarkable. The gallbladder, spleen, pancreas, and adrenal +glands demonstrate no gross abnormality. Both kidneys are +atrophic. Evaluation of solid organs is limited by lack of IV +contrast. + +There is a peritoneal dialysis catheter, coiled within the +pelvis, unchanged. There is a large amount of free fluid +throughout the abdomen, similar in appearance to the prior +study. + +CT OF THE PELVIS WITHOUT IV CONTRAST: Uterus and rectum are +grossly +unremarkable. However, assessment of the rectal wall is limited +without IV contrast. + +OSSEOUS STRUCTURES: Bones are diffusely sclerotic, which may be +related to renal osteodystrophy. There is bilateral +sacroiliitis. + +IMPRESSION: +1. Interval development of a moderate amount of free +intraperitoneal air, new from [**2141-10-13**]. A peritoneal +dialysis catheter is in place and could represent the route of +entry of free intraperitoneal air. However, as foci of air is +seen in the region of the proximal stomach and GE junction in +the setting of a recent endoscopy, perforation cannot be +excluded, though no frank extravasation of contrast is +identified. +2. New dilation and wall thickening of the entire esophagus, a +nonspecific finding that could relate to infectious or +inflammatory esophagitis; clinical correlation is recommended. +Esophagus is contrast-filled possibly representing reflux. +Hiatal hernia. +3. Anasarca, with moderate-sized pericardial effusion, pulmonary +edema, and small right pleural effusion. +4. Large amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. Imaging cannot exclude SBP, which should be +evaluated for clinically. +5. Focus of consolidation within the right lower lobe, could +represent +aspiration or pneumonia, but unchanged from the prior study. + +Gastric Biopsies ([**2141-10-18**]): Antrum: Corpus-type mucosa, no +diagnostic abnormalities recognized. Jejunum: Small intestinal +mucosa, no diagnostic abnormalities recognized. + +UE Venous U/S: No evidence of DVT of the left upper extremity, +without thrombus identified within the left subclavian vein. + + +Brief Hospital Course: +This is a 24 year old woman with ESRD secondary to SLE (started +peritoneal dialysis approximately one week prior to admission), +malignant HTN, h/o SVC syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. Her hospital course was +complicated by multiple transfers between the MICU and the floor +secondary to hypertensive urgency. + +# Abdominal Pain/Diarrhea: During the patient's admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. Infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. However, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. The patient was empirically placed on IV +flagyl, but this was discontinued when stool samples were +negative for C.difficile. Serial abdominal exams showed no +peritoneal signs. Peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. CT of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. Other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to SLE vasculitis, malignant +HTN, or microthrombosis and SLE enteritis. Surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. A heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible GI bleed. With regards to SLE vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to SLE. On [**10-18**], GI performed an EGD which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +Approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. Both cardiac, GI, and pulmonary etiologies were +considered for the origin of her epigastric pain. Pericarditis +was considered, but her EKG was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. Her lungs were also essentially unchanged from +[**2141-10-13**]. However, her abdominal CT on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. As a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. There were no major +findings: no evidence of perforation, obstruction, or infection. + The patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. At discharge, the patient only complained of +some mild incisional pain. + +# Hypertensive urgency: The patient was initially admitted to +the MICU with a blood pressure of 240/180. Her hospital course +was complicated by extremely labile HTN and was transferred back +and forth between the MICU and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +SBPs > 260. Throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. Her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. Multiple medication regimens +were attempted and changed throughout her hospital course. +However, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for SBPs > 180. At discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg PO. + +Her regimen as per Dr. [**Last Name (STitle) 4883**]: +Nifedipine SR 90 mg daily +Aliskiren 150 mg [**Hospital1 **] +Labetalol 300 mg TID +Hydralazine 75 mg TID +Clonidine patch 0.3 mg/24 hr patch qWed +When SBP>180, she then uses a hydralazine sliding scale. When +SBP>180, give 25 mg PO hydral every 30 min until SBP<150. You +can +use this for up to 2-3 hours. In between PO hydral doses, can +then also use 10 IV hydralazine. + +# ESRD: The etiology of the patient's ESRD is secondary to SLE. +Her Creatinine on admission was 7.9, which was near her baseline +of 8 - 9. During her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. Prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2L +per PD. After her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +Initially, the patient adamantly refused hemodialysis. However, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. As a +result, after a long coversation with her primary renal +physician, [**Name10 (NameIs) **] agreed to restart hemodialysis. A tunneled +catheter was placed in her R femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. She underwent hemodialysis two more times prior +to discharge. Upon discharge, her electrolytes were back to her +baseline. She is expected to undergo hemodialysis +(Tues/[**Last Name (un) **]/SAT) as an outpatient. + +# Anemia: During her admission, the patient's HCT was monitored +daily with HCT to low-mid 20's. On [**2141-10-17**], she was found to +have guaiac positive stools and her HCT was found to have +dropped to a low of 18.6. The patient was transfused a total of +2 units of [**Date Range **] between [**2141-10-17**] and [**2141-10-18**]. Epo Alfa SC was +also given on [**2141-10-17**]. She remained hemodynamically stable. GI +consulted and EGD results were as stated above. The patient's +HCT remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. Between [**2141-10-23**] - [**2141-10-24**], the patient had a HCT +drop from 26 to 20 in the setting of occult positive emesis. +She received two units of [**Month/Day/Year **] and her HCT returned to 28. GI +was aware and planned to perform a non-urgent EGD on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her HCT +returned to baseline. However, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +HCt remained stable and near baseline for the remiainder of her +hospital course. + +# H/O Thrombosis: The patient was initially placed on her home +dose of warfarin 2mg qd. Her INR on admission was 1.2. She was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. However, this was stopped +for her EGD and after she had evidence of a GI bleed. The +heparin drip was discontinued on [**10-22**]. The patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +HCT and in preparation for a possible GI intervention. After her +surgery, her coumadin was held and she was off the heparin drip, +but her INR continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. This was mostly attributed to nutritional deficiency +[**2-11**] poor PO intake, but there was concern for possible synthetic +dysfunction as well. As a result, she was given a test dose of +vitamin K, which she responded to well (Her INR came back down +to 1.4). As a result, her home dose of coumadin at 2 mg qday +was restarted. At discharge, her INR was still sub- therapeutic +at 1.4. + +Of note, the patient has a history of SVC syndrome and had a L +subclavian venous thrombosis. During the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her L face was noted to be slightly more swollen +than previously noted. As a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a DVT within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# SLE: Rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. Her outside rheumatologist +was also consulted. Both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# Obstructive sleep apnea: The patient was noted to have OSA +based on clinical nocturnal exam during admission. Patient +attempted 1 trial of CPAP at 2L/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +The paitent stated that she would pursue further work-up and +treatment for OSA as an outpatient. While the mask and CPAP +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# Metabolic Acidosis: The patient's bicarbonate on admission +was 13. Her baseline is normally between 16-20. She received +150mEq NaHCO3 over 24hrs from [**Date range (1) 43500**]. During her brief +returns to the MICU, her HC03 was 18-19, which was presumed to +be her baseline at home secondary to her CRF. At discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + +Medications on Admission: +Nifedipine 60 mg PO daily +Labetalol 900 mg PO TID +Hydralazine 50 mg PO TID +Clonidine 0.3 mg/24hr patch qWED +Lactulose 30 ml TID +Aliskiren 150 mg [**Hospital1 **] +Prednisone 4 mg daily +Warfarin 2mg PO daily +Calcitriol 1 mcg daily +Calcium carbonate 500mg QID +Dilaudid 2mg PO Q4-6hr prn pain + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*30 Patch Weekly(s)* Refills:*2* +2. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Hospital1 **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +5. Warfarin 2 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup Sig: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough. +[**Hospital1 **]:*1500 ML(s)* Refills:*0* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO Twice daily +(). +[**Hospital1 **]:*60 Tablet(s)* Refills:*2* +8. Hydralazine 25 mg Tablet Sig: Three (3) Tablet PO TID (3 +times a day): In addition to 75 mg TID, if SBP>180, take 1 tab +every 30 min until BP decreases to 150. If no improvement after +2 hours, call your doctor. +[**Last Name (Titles) **]:*300 Tablet(s)* Refills:*6* +9. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO DAILY +(Daily). +[**Last Name (Titles) **]:*1500 ML(s)* Refills:*2* +10. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Last Name (Titles) **]:*30 Tablet Sustained Release(s)* Refills:*2* +11. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO every six (6) +hours as needed for pain for 5 days. +[**Last Name (Titles) **]:*30 Tablet(s)* Refills:*0* +12. Colace 100 mg Capsule Sig: One (1) Capsule PO once a day. +[**Last Name (Titles) **]:*30 Capsule(s)* Refills:*2* +13. Miralax 17 gram (100 %) Powder in Packet Sig: One (1) PO +once a day. +[**Last Name (Titles) **]:*30 packets* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +end stage renal disease +malignant hypertension +abdominal free air +subclavian deep vein thrombosis +initiation of hemodialysis + +Secondary: +SLE +Anemia + + +Discharge Condition: +stable, pain well controlled, blood pressure at baseline + + +Discharge Instructions: +You were admitted for abdominal pain and then subsequently had a +very long hospital course with high blood pressures, severe +abdominal pain, some free air in your abdomen resulting in an +exploratory laparotomy. + +You have also been initiated on hemodialysis on +Tuesday/Thursday/Saturday schedule. + +Please take all medications as prescribed in the list that you +will be given at discharge. There have been some changes to your +medications. + +Please call your doctor if you have any worsening abdominal +pain, fevers, chills, nausea, vomiting, headache, palpitations, +diarrhea or any other concerning symptoms. + +Followup Instructions: +You will see Dr. [**Last Name (STitle) 4883**] at hemodialysis on Tuesday, [**11-7**], [**2141**]. You should have your coumadin level checked at this +appointment. + +Call Dr.[**Name (NI) 6045**] office at [**Telephone/Fax (1) 5189**] to schedule an +appointment in [**1-11**] weeks to have your staples removed. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 6735**] + +",115,2141-10-13 23:10:00,2141-11-03 18:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +this is a 24 year old woman with esrd secondary to sle (started +peritoneal dialysis approximately one week prior to admission), +malignant htn, h/o svc syndrome, and multiple thrombotic events +(on warfarin) who is presenting with persistent suprapubic/lower +abdominal pain and new onset severe epigastric pain w/ nausea +and vomiting, and hypertension. her hospital course was +complicated by multiple transfers between the micu and the floor +secondary to hypertensive urgency. + +# abdominal pain/diarrhea: during the patients admission, her +complaints of abdominal pain, nausea, diarrhea, and vomiting +progressively improved although no clear source of the symptoms +was found. infectious causes, including viral gastroenteritis, +peritonitis or c. dif colitis, were considered. however, during +the initial part of her admission, the patient remained afebrile +with an initial relative leukocytosis which trended to within +baseline limits. the patient was empirically placed on iv +flagyl, but this was discontinued when stool samples were +negative for c.difficile. serial abdominal exams showed no +peritoneal signs. peritoneal dialysis fluid analysis was +negative for leukocytosis without organisms on gram stain. ct of +the abdomen on [**10-13**] showed evidence of multifocal small bowel +thickening and gastric wall edema, but no acute process. other +etiologies of her abdomoinal pain were also considered including +mesenteric ischemia bowel secondary to sle vasculitis, malignant +htn, or microthrombosis and sle enteritis. surgery was +consulted and felt that the patient did not have an ischemic +bowel as serial lactates were negative and serial abdominal +exams showed improvement in pain. a heparin drip and warfarin +were started for treatment of possible microthrombotic ischemia, +although this was stopped when the patient had evidence of a +possible gi bleed. with regards to sle vasculitis/enteritis, +rheumatology was consulted and they did not believe her symptoms +were related to sle. on [**10-18**], gi performed an egd which showed +erosion in the gastroesophageal junction yet an otherwise normal +small bowel enteroscopy to third part of the duodenum; biopsies +of stomach antrum and proximal jejunum were negative. + +approximately halfway through her hospital course, the patient +complained of severe epigastric pain in addition to her lower +abdominal pain. both cardiac, gi, and pulmonary etiologies were +considered for the origin of her epigastric pain. pericarditis +was considered, but her ekg was unchanged from prior studies and +there had been on interval increase in her pericardial effusion +since [**2141-10-13**]. her lungs were also essentially unchanged from +[**2141-10-13**]. however, her abdominal ct on [**2141-10-26**] showed a large +amount of free intra-abdominal fluid in the setting of +peritoneal dialysis. as a result, the patient underwent an +exploaratory laparotomy on [**2141-10-27**]. there were no major +findings: no evidence of perforation, obstruction, or infection. + the patient tolerated the procedure well and immediately +reported that both her epigastric and suprapubic pain were gone +after the surgery. at discharge, the patient only complained of +some mild incisional pain. + +# hypertensive urgency: the patient was initially admitted to +the micu with a blood pressure of 240/180. her hospital course +was complicated by extremely labile htn and was transferred back +and forth between the micu and the floor on three separate +occasions ([**10-19**], [**10-21**], and [**10-22**]) for identical episodes of +sbps > 260. throughout all of these episodes of hypertensive +urgency, the patient remained asymptomatic from a neuro and +cardiac standpoint except for occasional headache. her final +transfer to the floor occured [**2141-10-25**], where she remained for +the rest of her hospital course. multiple medication regimens +were attempted and changed throughout her hospital course. +however, her blood pressures finally stabilized when she was +placed back on her oral home regimen, which includes nifedipine, +clonidine patch, labetalol, aliskiren, and hydralazine, with a +hydralazine sliding scale for sbps > 180. at discharge, the +only change from her home regimen that was made was increasing +her nifedipine to 90 mg po. + +her regimen as per dr. [**last name (stitle) 4883**]: +nifedipine sr 90 mg daily +aliskiren 150 mg [**hospital1 **] +labetalol 300 mg tid +hydralazine 75 mg tid +clonidine patch 0.3 mg/24 hr patch qwed +when sbp>180, she then uses a hydralazine sliding scale. when +sbp>180, give 25 mg po hydral every 30 min until sbp<150. you +can +use this for up to 2-3 hours. in between po hydral doses, can +then also use 10 iv hydralazine. + +# esrd: the etiology of the patients esrd is secondary to sle. +her creatinine on admission was 7.9, which was near her baseline +of 8 - 9. during her admission, the patient underwent multiple +trials of peritoneal dialysis, but was unable to tolerate it on +a consistent basis secondary to abdominal pain. prior to her +exploratory laparotomy, she was scheduled to have peritoneal +dialysis four times per day over 4hrs with 2% solution at 1.2l +per pd. after her exploratory laparotomy, surgery strongly +advised the medical team that she should not restart peritoneal +dialysis until she was at least 3 weeks out from her surgery. +initially, the patient adamantly refused hemodialysis. however, +over several days, she became hyperkalemic and increased +swelling was noted bilaterally in her ankles and feet. as a +result, after a long coversation with her primary renal +physician, [**name10 (nameis) **] agreed to restart hemodialysis. a tunneled +catheter was placed in her r femoral vein on [**2141-11-1**] and she +subsequently started hemodialysis the same day, which she +tolerated well. she underwent hemodialysis two more times prior +to discharge. upon discharge, her electrolytes were back to her +baseline. she is expected to undergo hemodialysis +(tues/[**last name (un) **]/sat) as an outpatient. + +# anemia: during her admission, the patients hct was monitored +daily with hct to low-mid 20s. on [**2141-10-17**], she was found to +have guaiac positive stools and her hct was found to have +dropped to a low of 18.6. the patient was transfused a total of +2 units of [**date range **] between [**2141-10-17**] and [**2141-10-18**]. epo alfa sc was +also given on [**2141-10-17**]. she remained hemodynamically stable. gi +consulted and egd results were as stated above. the patients +hct remained stable (hovering between 25 - 27) from [**2141-10-19**] - +[**2141-10-23**]. between [**2141-10-23**] - [**2141-10-24**], the patient had a hct +drop from 26 to 20 in the setting of occult positive emesis. +she received two units of [**month/day/year **] and her hct returned to 28. gi +was aware and planned to perform a non-urgent egd on [**10-25**] or +[**10-26**] as the patient was hemodynamically stable and her hct +returned to baseline. however, this did not occur as the +patient went for an exploratory laparotomy on [**2141-10-27**] and her +hct remained stable and near baseline for the remiainder of her +hospital course. + +# h/o thrombosis: the patient was initially placed on her home +dose of warfarin 2mg qd. her inr on admission was 1.2. she was +also started heparin drip secondary to concern for ischemic +bowel [**2-11**] microthrombotic disease. however, this was stopped +for her egd and after she had evidence of a gi bleed. the +heparin drip was discontinued on [**10-22**]. the patient remained off +heparin and coumadin from [**2141-10-23**] - [**2141-10-25**] given her drop in +hct and in preparation for a possible gi intervention. after her +surgery, her coumadin was held and she was off the heparin drip, +but her inr continued to drift up, getting as high as 2.6 on +[**2141-10-30**]. this was mostly attributed to nutritional deficiency +[**2-11**] poor po intake, but there was concern for possible synthetic +dysfunction as well. as a result, she was given a test dose of +vitamin k, which she responded to well (her inr came back down +to 1.4). as a result, her home dose of coumadin at 2 mg qday +was restarted. at discharge, her inr was still sub- therapeutic +at 1.4. + +of note, the patient has a history of svc syndrome and had a l +subclavian venous thrombosis. during the last few days of her +hospital stay, the patient complained of increased tongue +swelling and her l face was noted to be slightly more swollen +than previously noted. as a result, she underwent upper +extremity venous ultrasound on [**2141-11-2**], which showed no +evidence of a dvt within the left upper extremity and the +previously noted thrombus within the left subclavian vein was +not seen as well. + +# sle: rheumatology was consulted several times throughout her +hospital course, but they did not think that a lupus flare was +contributing to her presentation. her outside rheumatologist +was also consulted. both parties wanted to keep the patient on +her home dose of prednisone of 4 mg qday, which was continued +throughout her entire hospital course. + +# obstructive sleep apnea: the patient was noted to have osa +based on clinical nocturnal exam during admission. patient +attempted 1 trial of cpap at 2l/min for 1-2 hrs with nasal mask, +however did not tolerate as she complained of claustrophobia. +the paitent stated that she would pursue further work-up and +treatment for osa as an outpatient. while the mask and cpap +machine were at her bedside throughout her hospital course, the +patient rarely used it. + +# metabolic acidosis: the patients bicarbonate on admission +was 13. her baseline is normally between 16-20. she received +150meq nahco3 over 24hrs from [**date range (1) 43500**]. during her brief +returns to the micu, her hc03 was 18-19, which was presumed to +be her baseline at home secondary to her crf. at discharge, +having undergone three rounds of hemodialysis, her bicarbonate +was within normal limits at 28. + + ","PRIMARY: [Malignant essential hypertension] +SECONDARY: [Renal dialysis status; Epilepsy, unspecified, without mention of intractable epilepsy; Constipation, unspecified; Anemia in chronic kidney disease; Abnormal coagulation profile; Obstructive sleep apnea (adult)(pediatric); Other diseases of lung, not elsewhere classified; Other chest pain; Fever, unspecified; Rash and other nonspecific skin eruption; Other chronic pulmonary heart diseases; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified disease of pericardium; Other ascites; Acidosis; Hyposmolality and/or hyponatremia; Abdominal pain, other specified site; Abdominal pain, epigastric; Nausea with vomiting; Diarrhea; Systemic lupus erythematosus; Hyperparathyroidism, unspecified; Anemia, unspecified; Thrombocytopenia, unspecified; Esophageal reflux]" +109,158995.0,14807,2142-02-26,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",95,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,158995.0,14807,2142-02-26,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",87,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,158995.0,14807,2142-02-26,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",74,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,158995.0,14807,2142-02-26,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",65,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,158995.0,14807,2142-02-26,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",45,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,158995.0,14807,2142-02-26,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",37,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,158995.0,14807,2142-02-26,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",34,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,158995.0,14807,2142-02-26,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",9,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,124657.0,14804,2142-01-20,14796,139061.0,2141-09-14,Discharge summary,"Admission Date: [**2141-9-11**] Discharge Date: [**2141-9-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Right leg pain. + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 y.o. F with lupus, Chronic Kidney Disease V +(not currently on HD or PD), and multiple admissions for +hypertensive urgency/emergency, who presented to the ED for +continued R leg pain that starts in her R buttocks and refers +down her R leg. She describes it as feeling like the pain is +deep within her bone. The pain was [**10-20**] in the AM, and she +felt like she couldn't get out of bed. Denies any swelling of +her RLE. When getting VS in [**Name (NI) **], pt noted to be very +hypertensive at 263/176. The patient reportedly has baseline +SBPs in 130-170s. She took her hydralazine, aliskirien, and +labetalol at 5 AM on day of admission. She denies any recent +recrational drug use including cocaine and amphetamines. She +denies headache, vision changes, double vision, chest pain, +shortness of breath, abdominal pain, BRBPR, dysuria. During MD +interview, the patient was nauseous and had small amount of +emesis of a recent Coolata. Pt states that flushing her PD cath +causes a large amount of stomach pain. +. +Of note, the patient was recently admitted from 08.26-29.08. The +patient initially presented to the ED after referral from her +nephrologist's office where she had complaints of right leg pain +and was found to be hypertensive to 250/145. She was admitted +after initiation of a labetalol drip and nitropaste with +improvement in sbp to 180. The patient did receive 2 U of PRBC's +during this hospitalization for baseline anemia. The patient did +have a work-up for her right leg pain complaints with plain +films of the right hip and MRI of the L-spine which did not +reveal an explanation for her symptoms and did rule out +avascular necrosis. The patient received dilaudid for pain +control and was ambulating without pain prior to discharge. In +addition, the patient completed a course of ciprofloxacin for a +positive UA with negative cultures. The patient was unable to +tolerate peritoneal dialysis for unclear reasons. Peritoneal +dialysate culture was negative for infection. +. +In the ED: VS T 98.2 HR 101 BP 263/176 RR 20 O2 sat 100% RA. +BPs in ED ranged from [**Telephone/Fax (3) 43494**]-175 with HR in 96-108. +Initially given labetalol 10 mg IV x 1 and then started on +labetalol gtt for her elevated blood pressures and titrated to 3 +mg/min. LENI of R leg was negative. CXR performed. Given +morphine 4 mg IV x 1 for leg pain. Per ED, cannot do V/Q scan +due to volume overload after talking with radiology. Renal c/s +initiated. A-line placed. + +Past Medical History: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]). +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD. +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome. +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN. +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], 8/[**2140**]). +- HOCM: Last noted on echo [**8-17**]. +- Anemia. +- History of left eye enucleation [**2139-4-20**] for fungal infection. +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +. +PAST SURGICAL HISTORY: +- Placement of multiple catheters including dialysis. +- Tonsillectomy. +- Left eye enucleation in [**2140-4-10**]. +- PD catheter placement in [**2141-5-11**]. + +Social History: +Single. Recently moved into her own apartment. On disability. +Denies EtOH, tobacco or recreational drug use. + +Family History: +Negative for autoimmune diseases, thrombophilic disorders. +Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: T 98.9 [**Telephone/Fax (2) 43495**] 99$% RA +GEN: NAD, pleasant female sitting in bed with moon facies +HEENT: EOMI of R eye, L eye prosthesis, no exudate, no erythema, +MMM, no LAD +CHEST: CTAB except at R base with decreased breath sounds; no +w/r/r +CV: tachy, normal S1S2, II/VI systolic murmur accentuated with +Valsalva +ABD: NDNT, soft, NABS, PD cathether placed in LLQ, dressing +c/d/i +EXT: no c/c/e, strength of LEs [**5-15**] and symmetric bilaterally. +Negative straight leg test, no pain with internal rotation, +external rotation, extension, adduction or abduction. Some pain +on flexion at the hip. +NEURO: II - XII intact to direct testing. No deficit in light +tough sensation. Gait normal. +DERM: no rashes noted + + +Pertinent Results: +LABS AT ADMISSION: +[**2141-9-11**] 11:43AM GLUCOSE-86 UREA N-49* CREAT-8.1* SODIUM-139 +POTASSIUM-5.0 CHLORIDE-110* TOTAL CO2-16* ANION GAP-18 +[**2141-9-11**] 11:43AM CALCIUM-6.2* PHOSPHATE-5.8* MAGNESIUM-1.6 +[**2141-9-11**] 11:43AM PT-18.4* PTT-42.8* INR(PT)-1.7* +[**2141-9-11**] 07:00AM WBC-5.5 RBC-2.88* HGB-8.1* HCT-24.7* MCV-86 +MCH-28.1 MCHC-32.8 RDW-18.0* +[**2141-9-11**] 07:00AM NEUTS-74.7* LYMPHS-17.5* MONOS-4.2 EOS-3.3 +BASOS-0.2 +[**2141-9-11**] 07:00AM PLT COUNT-101* +UA: moderate leuk, small blood, negative nitrite, protein 100, +21-50 WBC +. +MICROBIOLOGY: +Urine culture ([**2141-9-11**]): Mixed flora +. +STUDIES: +Cardiology Report ECG Study Date of [**2141-9-11**] 6:55:16 AM +Sinus tachycardia. The tracing is marred by baseline artifact. +There is +left atrial enlargement. Compared to the previous tracing of +[**2141-9-5**] +the rate has increased. The axis is more rightward. Otherwise, +no diagnostic interim change. +. +UNILAT LOWER EXT VEINS RIGHT Study Date of [**2141-9-11**] 8:54 AM +[**Doctor Last Name **]-scale and Doppler son[**Name (NI) 1417**] of the right common femoral, +superficial +femoral, and popliteal veins demonstrate normal flow, +compressibility, +augmentation, waveforms. Appropriate color flow and compression +is noted +within the calf veins. No intraluminal thrombus is present. +IMPRESSION: No evidence of right lower extremity DVT. +. +TTE ([**2140-8-26**]): The left atrium is normal in size. There is +severe symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Regional left ventricular +wall motion is normal. Left ventricular systolic function is +hyperdynamic (EF>75%). There is a mild resting left ventricular +outflow tract obstruction. The gradient increased with the +Valsalva manuever. The findings are consistent with hypertrophic +obstructive cardiomyopathy (HOCM). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) appear +structurally normal with good leaflet excursion. No masses or +vegetations are seen on the aortic valve. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is a trivial/physiologic pericardial effusion. +. +R HIP XR [**2141-9-6**]: No acute fracture or dislocation. +. +MRI L-SPINE [**2141-9-6**]: Diffuse low-signal intensity is identified +in the bone marrow of the lumbar and lower thoracic spine as +described above, possibly related with anemic changes, please +correlate clinically. There is no evidence of spinal canal +stenosis or neural foraminal narrowing at the different +intervertebral disc spaces. + +LAB RESULTS AT DISCHARGE: +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2141-9-14**] 06:15AM 4.0 2.63* 7.6* 23.1* 88 29.1 33.0 18.0* +100* +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2141-9-14**] 06:15AM 100 44* 8.1* 137 4.8 109* 17* 16 +CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2141-9-14**] 06:15AM 6.8* 5.4* 1.6 +CALCIUM freeCa +[**2141-9-14**] 11:30AM 0.94* + + +Brief Hospital Course: +ICU course: +EKG showed no change from prior, and CXR showed a suggestion of +RLL/R diaphragm haziness. IV labetalol was started, and SBPS +dropped from 200s to 130s-160s. The patient had no symptoms of +end-organ damage. The renal team was consulted, and recommended +no change to home medication regimen. The patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + When stable, patient succesfully switched to PO meds and +transferred to the floor. +. +[**Hospital1 **] history: +. +1. Hypertensive urgency: During the patient's [**Hospital1 **] stay, her +SBPs ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. She was maintained on her home oral +medication regimen. At night, she became more hypertensive, +with SBP to the 170s-180s, which was controlled with both IV +hydralazine and PO nifedipine. PO nifedipine was most +successful at bringing her SBP back to her baseline. SBP at +discharge was 140. Throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. The renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. Right leg pain: Upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in R buttock and posterior thigh, much +exacerbated with standing. Of note, lumbar spine MRI and R hip +XR on most recent admission were both negative. Her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. Her pain when she was symptomatic +was controlled well with PO dilaudid. If the pain recurs, an +MRI of the right hip can be considered to evaluate for +osteonecrosis. +. +3. UTI: The patient had a urinalysis suggestive of UTI, though +she remained asymptomatic throughout. She was treated with a +three day course of ciprofloxacin. Her urine culture showed +mixed flora consistent with skin contamination. +. +4. ESRD: The patient has end-stage renal disease due to her +lupus. The patient's creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. She was followed by the renal consult +service. Her potassium remained stable. Her calcium was low +during admission, and supplemental calcium was given in addition +to starting Calcitriol. She was not dialyzed through her PD +catheter secondary to discomfort, but may reinitiate PD as an +outpatient. Her laboratories will be checked as an outpatient +in renal clinic. +. +5. Anemia: The patient's hematocrit remained near her baseline +low 20s throughout her stay. She has anemia from chronic kidney +disease and chronic disease. The patient is not on Epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. Prior SVC thrombus: The patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with INR goal 2.5 to 3.0. +. +7. Systemic lupus erythematosus: No active issues. The +patient's home prednisone regimen was continued. + +Medications on Admission: +- Prednisone 5 mg Daily +- Coumadin 2 mg at bedtime +- Nifedipine 60 mg Sustained Release Daily +- Hydralazine 50 mg every 8 hours +- Clonidine 0.3 mg/24 hr Patch Weekly every Wednesday +- Ergocalciferol (Vitamin D2) 50,000 unit WEEKLY +- Aliskiren 150 mg Twice daily +- Docusate Sodium 100 mg 2 times a day +- Labetalol 900 mg three times a day +- Lactulose 15-30 ml once a day: goal is [**1-11**] soft bowel +movements per day + +Discharge Medications: +1. Prednisone 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO QID (4 times a day). +4. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +5. Calcitriol 0.5 mcg Capsule Sig: Two (2) Capsule PO DAILY +(Daily). +Disp:*60 Capsule(s)* Refills:*0* +6. Hydromorphone 2 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed for Pain. +7. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Hydralazine 50 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours). +11. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +Q6H (every 6 hours) as needed for itching. + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary diagnosis: +- Hypertensive urgency +- Right lower extremity pain +- Urinary tract infection + +Secondary diagnosis: +- Systemic lupus erythematosus. Diagnosed [**2134**] (16 years old) +when she had swollen fingers, arm rash and arthralgias. Previous +treatment with cytoxan, cellcept; currently on prednisone. +Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +- CKD/ESRD. Diagosed [**2135**]. Initiated dialysis [**2137**]. PD catheter +placement [**5-18**]. Pt reluctant to start PD +- Malignant hypertension. Baseline BPs 180's - 120's. History of +hypertensive crisis with seizures. History of two +intraparenchymal hemorrhages that were thought to be due to the +posterior reversible leukoencephalopathy syndrome +- Thrombocytopenia. TTP (got plasmapheresisis) versus malignant +HTN +- Thrombotic events. SVC thrombosis ([**2139**]); related to a +catheter. Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], 9/[**2140**]). +Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]). +Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +- HOCM: Last noted on echo [**8-17**] +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion. +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] + + +Discharge Condition: +Stable systolic blood pressure over past 24 hours. + + +Discharge Instructions: +You were admitted to the hospital for uncontrolled high blood +pressure. You spent one day in the intensive care unit, where +you were treated with intravenous medication to lower your blood +pressure. You were then transferred to a regular hospital +floor, where your blood pressure was managed with your home oral +medications. You were also treated for urinary tract infection +with antibiotics. Your right leg pain improved during +admission, and we are unsure of the cause of this pain. You +should discuss the need for an MRI of the hip if the pain +returns when you meet with your primary care doctor. + +Please call your physician or return to the emergency room if +you experience fever, chills, chest pain, difficulty breathing, +abdominal pain, headache, changes in your vision, or any other +symptoms that are concerning. + +Please take your medications as prescribed. +- Calcitriol was added to your medications. +- You should hold Coumadin for two days and restart Saturday, +[**2141-9-16**]. You should have your INR checked at your visit in +kidney clinic [**2141-9-18**]. +- You can take Dilaudid 2-4 mg every eight hours as needed for +pain. You should be vigilant about taking lactulose if you need +to take Dilaudid. +- You should continue Lactulose as per Dr.[**Name (NI) 12913**] +instructions. +- No other changes were made. + +Please keep follow up appointments as described below. + +Followup Instructions: +Please call the office of your kidney doctor, Dr. [**Last Name (STitle) 4883**], at +([**Telephone/Fax (1) 773**] to schedule an appointment for [**Last Name (LF) 766**], [**9-19**] as discussed. + +Follow up with your lung doctor: Provider: [**First Name8 (NamePattern2) **] [**Name8 (MD) **], MD +Phone:[**Telephone/Fax (1) 612**] Date/Time:[**2141-9-21**] 1:00 + +Follow up with your new primary care doctor: Provider: [**First Name11 (Name Pattern1) 488**] +[**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] Date/Time:[**2141-9-28**] 10:00 + + + +",128,2141-09-11 10:12:00,2141-09-14 20:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +icu course: +ekg showed no change from prior, and cxr showed a suggestion of +rll/r diaphragm haziness. iv labetalol was started, and sbps +dropped from 200s to 130s-160s. the patient had no symptoms of +end-organ damage. the renal team was consulted, and recommended +no change to home medication regimen. the patient was found to +by hypocalcemic, and was started on calcium replacement therapy. + when stable, patient succesfully switched to po meds and +transferred to the floor. +. +[**hospital1 **] history: +. +1. hypertensive urgency: during the patients [**hospital1 **] stay, her +sbps ranged from 140s-160s during the day, which is her baseline +systolic blood pressure. she was maintained on her home oral +medication regimen. at night, she became more hypertensive, +with sbp to the 170s-180s, which was controlled with both iv +hydralazine and po nifedipine. po nifedipine was most +successful at bringing her sbp back to her baseline. sbp at +discharge was 140. throughout her hospitalization, the patient +had no symptoms/signs of hypertensive emergency, including no +seizures, no acute worsening of renal function, no headache, +nausea, visual and mental status disturbances, chest pain, +abdominal pain, or urinary symptoms. the renal service followed +her throughout her course and did not recommend any changes to +her regimen, but will follow her closely as an outpatient. +. +2. right leg pain: upon arrival on the floor, the patient +complained of [**2143-4-15**] pain in r buttock and posterior thigh, much +exacerbated with standing. of note, lumbar spine mri and r hip +xr on most recent admission were both negative. her pain was +intermittent, likely secondary to sciatica, and had resolved by +the time of her discharge. her pain when she was symptomatic +was controlled well with po dilaudid. if the pain recurs, an +mri of the right hip can be considered to evaluate for +osteonecrosis. +. +3. uti: the patient had a urinalysis suggestive of uti, though +she remained asymptomatic throughout. she was treated with a +three day course of ciprofloxacin. her urine culture showed +mixed flora consistent with skin contamination. +. +4. esrd: the patient has end-stage renal disease due to her +lupus. the patients creatinine remained stable at 7.9-8.4 +throughout her hospitalization, which was similar to her +baseline renal function. she was followed by the renal consult +service. her potassium remained stable. her calcium was low +during admission, and supplemental calcium was given in addition +to starting calcitriol. she was not dialyzed through her pd +catheter secondary to discomfort, but may reinitiate pd as an +outpatient. her laboratories will be checked as an outpatient +in renal clinic. +. +5. anemia: the patients hematocrit remained near her baseline +low 20s throughout her stay. she has anemia from chronic kidney +disease and chronic disease. the patient is not on epopoeitin +as an outpatient, likely due to her malignant hypertension. +. +6. prior svc thrombus: the patient has a reported history of +prior thrombus related to catheter placement in [**2139**], and was +maintained on warfarin with inr goal 2.5 to 3.0. +. +7. systemic lupus erythematosus: no active issues. the +patients home prednisone regimen was continued. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Chronic glomerulonephritis in diseases classified elsewhere; Chronic kidney disease, Stage V; Urinary tract infection, site not specified; Other primary cardiomyopathies; Systemic lupus erythematosus; Sciatica; Hyperpotassemia; Thrombocytopenia, unspecified; Abnormal coagulation profile; Hyperparathyroidism, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism]" +109,131376.0,14862,2142-07-08,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",177,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,131376.0,14862,2142-07-08,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",169,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,131376.0,14862,2142-07-08,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",166,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,131376.0,14862,2142-07-08,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",141,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,131376.0,14862,2142-07-08,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",132,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,131376.0,14862,2142-07-08,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",107,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,131376.0,14862,2142-07-08,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",99,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,131376.0,14862,2142-07-08,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",77,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,196721.0,14863,2142-07-23,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",66,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,196721.0,14863,2142-07-23,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",48,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,196721.0,14863,2142-07-23,14860,136572.0,2142-06-20,Discharge summary,"Admission Date: [**2142-6-18**] Discharge Date: [**2142-6-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2145**] +Chief Complaint: +Acute Onset Dyspnea + +Major Surgical or Invasive Procedure: +Dialysis + + +History of Present Illness: +Please see MICU note for full details. In brief this is a 24 +y.o. woman with SLE, ESRD on HD, hx malignant HTN, h/o SVC +syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, frequently admitted +with hypertensive urgency/emergency who was admitted with acute +onset dyspnea after 2 weeks without dialysis given to unable to +get transportation ? despite Dr. [**Last Name (STitle) 7473**] attempting to arrange +transport for her (? refused to come). She was admitted +therefore on [**6-18**] to micu with VS: T 100.4 HR 108 BP 240/180 RR +28 POx100 RA. She was treated with nitro gtt, labetolol gtt and +dilaudid-these gtts were stopped at 0700. In the micu she was +dialyzed with 1.7L fluid removal (though + 300cc given +tranfusion). Her SOB is improved. Her hct was also noted to be +low (18->from 22 [**2142-6-5**]) so transfused 2 units PRBC's, recent +EGD with gastric ulcer [**5-29**], guaiac negative in ED, no BM in +unit, hemolysis w/u negative. BP in icu 140/106 currently but of +note was hypotensive on HD to 86/62. She notes sob improved +rapidly on arrival. + +ROS: Currently she has no complaints. She notes at home her +abdominal pain is at baseline for her, felt mid epigastric, for +which she takes dilaudid 4mg up to [**Hospital1 **]. She has been getting HD +via right femoral catheter which is not painful, no discharge +from the sight. She denies HA, visual changes, cough, chest pain +or pressure, orthostatic changes, palpitations, nausea, +vomiting, constipation, diarrhea, melena, brbpr, dysuria, +hematuria, rash, swelling, orthopnea, pnd. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - T: 97.7, BP: 140/99 P: 88 R: 19 O2: 98% on RA +General: Sleeping comfortably but awakens easily, alert, +oriented x3 +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM, moon facies +Neck: supple, JVP flat, no LAD, full ROM, left EJ in place +Lungs: coarse BS throughout, no W/R/R, no decreased BS at bases + +CV: S1, S2 nl, no m/r/g appreciated +Abdomen: Firm, non-tender to palpation, no masses or +organomegally +Ext: Warm, well perfused, 1+ DP/PT, no clubbing, cyanosis or +edema +Neuro: a&o x3, motor [**5-15**] UE/LE bilaterally + + +Pertinent Results: +[**2142-6-18**] 05:28PM HCT-26.0*# +[**2142-6-18**] 11:38AM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-NORMAL MICROCYT-OCCASIONAL POLYCHROM-NORMAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-6-18**] 05:04AM GLUCOSE-85 UREA N-72* CREAT-10.4* SODIUM-139 +POTASSIUM-5.5* CHLORIDE-109* TOTAL CO2-14* ANION GAP-22* +[**2142-6-18**] 05:04AM LD(LDH)-264* TOT BILI-0.2 +[**2142-6-18**] 05:04AM CALCIUM-6.6* PHOSPHATE-6.5* MAGNESIUM-1.6 +[**2142-6-18**] 05:04AM HAPTOGLOB-142 +[**2142-6-18**] 05:04AM WBC-3.4* RBC-1.93* HGB-5.8* HCT-17.0* MCV-88 +MCH-30.0 MCHC-34.2 RDW-18.4* +[**2142-6-18**] 05:04AM PLT COUNT-97* +[**2142-6-18**] 01:34AM GLUCOSE-84 UREA N-70* CREAT-10.5*# SODIUM-136 +POTASSIUM-5.6* CHLORIDE-108 TOTAL CO2-14* ANION GAP-20 +[**2142-6-18**] 01:34AM estGFR-Using this +[**2142-6-18**] 01:34AM ALT(SGPT)-10 AST(SGOT)-39 ALK PHOS-108 TOT +BILI-0.2 +[**2142-6-18**] 01:34AM LIPASE-115* +[**2142-6-18**] 01:34AM ALBUMIN-3.2* CALCIUM-6.6* PHOSPHATE-6.8* +MAGNESIUM-1.7 +[**2142-6-18**] 01:34AM WBC-4.5 RBC-2.08* HGB-6.0* HCT-18.3* MCV-88 +MCH-28.6 MCHC-32.5 RDW-18.6* +[**2142-6-18**] 01:34AM NEUTS-78.5* LYMPHS-16.5* MONOS-3.0 EOS-1.4 +BASOS-0.6 +[**2142-6-18**] 01:34AM PLT COUNT-104* +[**2142-6-18**] 01:34AM PT-15.0* PTT-33.6 INR(PT)-1.3* + +Brief Hospital Course: +# Dyspnea: Pt's dypsnea improved on admission to the ED prior to +HD. Based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. Upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# Anemia: Pt's baseline 1 month ago noted to be low 30s, since +then her Hct has trended down to 22 several week prior to +admission. As she missed dialysis she was not able to reserve +her Eopgen which likely complicated her anemia. Pt underwent +hemolysis workup in the ICU which was ultimately negative. She +was given several units of PRBC and bumped her Hct +appropriately. She was noted to be guaiac negative on +examination. + +# Hypertension: Pt was initially admitted with hypertension. +Following transition to the floor she was placed on her home +regimen. She was noted to be hypotensive in dialysis which is +likely due to her being on Labetalol, Nitro gtt on dialysis. Pt +was discharged on her home BP regimen with follow up with her +nephrologist. + +# Chronic Abdominal Pain: Pt had noted some intermittent +abdominal pain which has been chronic. Lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. Pt was able to tolerate a PO diet prior to her +discharge. Pt was continued on her outpatient regimen of +Dilaudid, Fentanyl patch, Neurontin. + +# GE junction Ulcer: Pt was continued on her PPI regimen [**Hospital1 **]. + +# SLE: Pt was continued on her home regimen of Prednisone 4mg +daily + +# History of DVT: Pt had a sub-therapeutic INR on admission. She +was discharged on Warfarin 3mg daily. + +# ESRD on HD: Pt was admitted for dyspnea in the setting of +missing 2 weeks of HD. The renal team followed Ms. [**Known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. Pt was continued on Sevelamer and +Epogen. + +# Seizure D/O: Pt was continued on her home regimen of keppra. + +# Depression: Pt was continued on her home regimen of Celexa. + + +Medications on Admission: +1. Nifedipine 90 mg Tablet Sustained Release PO QAM +2. Nifedipine 60 mg Tablet Sustained Release PO QHS +3. Lidocaine 5 % transdermal one daily +4. Aliskiren 150 mg PO BID +5. Citalopram 20 mg PO DAILY (Daily). +6. Fentanyl 25 mcg/hr Patch Q72H (every 72 hours). +7. Prednisone 4mg PO DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Transdermal QSAT +9. Clonidine 0.3 mg/24 hr Patch Weekly Transdermal QSAT +10. Sevelamer HCl 400 mg Four (4) Tablet PO TID W/MEALS +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +13. Hydralazine 100 mg PO Q8H +14. Hydromorphone 2 mg 1-2 Tablets PO Q6H as needed for pain. +15. Pantoprazole 40 mg PO Q12H +16. LeVETiracetam 1,000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24 H (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: Malignant HTN, ESRD on HD, Shortness of breath +Secondary: Lupus + + +Discharge Condition: +Stable, afebrile + + +Discharge Instructions: +You were admitted to the hospital after you noticed some +shortness of breath. Whilst in the hospital you were noted to +have a low blood level (anemia) and you some fluid in your +lungs. We think your blood level was low because you were not +receiving your Epo shots, we think the fluid is from not +receiving dialysis. Before you were discharged from the hospital +your breathing was better. + +We recommend that you continue going to dialysis. + +We made no changes to your medications. + +If you notice any fevers, chills, nausea, vomiting, shortness of +breath, lightheadedness please return to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 +Provider: [**First Name4 (NamePattern1) **] [**Name Initial (NameIs) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-27**] 2:00 + + + [**Name6 (MD) **] [**Name8 (MD) **] MD [**MD Number(2) 2158**] + +",33,2142-06-18 03:11:00,2142-06-20 16:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ANEMIA," +# dyspnea: pts dypsnea improved on admission to the ed prior to +hd. based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# anemia: pts baseline 1 month ago noted to be low 30s, since +then her hct has trended down to 22 several week prior to +admission. as she missed dialysis she was not able to reserve +her eopgen which likely complicated her anemia. pt underwent +hemolysis workup in the icu which was ultimately negative. she +was given several units of prbc and bumped her hct +appropriately. she was noted to be guaiac negative on +examination. + +# hypertension: pt was initially admitted with hypertension. +following transition to the floor she was placed on her home +regimen. she was noted to be hypotensive in dialysis which is +likely due to her being on labetalol, nitro gtt on dialysis. pt +was discharged on her home bp regimen with follow up with her +nephrologist. + +# chronic abdominal pain: pt had noted some intermittent +abdominal pain which has been chronic. lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. pt was able to tolerate a po diet prior to her +discharge. pt was continued on her outpatient regimen of +dilaudid, fentanyl patch, neurontin. + +# ge junction ulcer: pt was continued on her ppi regimen [**hospital1 **]. + +# sle: pt was continued on her home regimen of prednisone 4mg +daily + +# history of dvt: pt had a sub-therapeutic inr on admission. she +was discharged on warfarin 3mg daily. + +# esrd on hd: pt was admitted for dyspnea in the setting of +missing 2 weeks of hd. the renal team followed ms. [**known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. pt was continued on sevelamer and +epogen. + +# seizure d/o: pt was continued on her home regimen of keppra. + +# depression: pt was continued on her home regimen of celexa. + + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Anemia of other chronic disease; Hyperpotassemia; Systemic lupus erythematosus; Abdominal pain, other specified site; Other chronic pain; Hypotension, unspecified; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Depressive disorder, not elsewhere classified; Personal history of venous thrombosis and embolism; Noncompliance with renal dialysis]" +109,196721.0,14863,2142-07-23,14861,174489.0,2142-07-04,Discharge summary,"Admission Date: [**2142-7-3**] Discharge Date: [**2142-7-4**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2817**] +Chief Complaint: +dyspnea, hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +discharged on [**7-1**] after presenting for hypertensive urgency and +dyspnea for which she received iv medication in the ED, but was +otherwised managed with oral antihypertensives and CPAP. +. +She was doing well until the evening of [**7-2**] when she notes the +gradual onset of dyspnea. She denied f/c/cp/ha/abd +pain/diarrhea, or constipation. She was having regular, soft, +daily BMs. +. +On [**7-3**] she awoke, and describes n/v x 2, with increasing +dyspnea, and headache. She did not want to wait until dialysis +at 4PM and therefore presented to [**Hospital1 18**]. +. +In ED VS= 97.7 [**Telephone/Fax (2) 43606**] 100%RA. Labs were notable for HCT +23, PLT 66, WBC 3.3, all roughly at baseline. CXR without acute +process, ECG unchanged from prior. No UA sent, though she does +make some urine. She was started on nitro gtt with modest +improvement of SBPs to 210s, then labetalol 20mg iv x1 followed +by labetalol gtt with BP 221/130 at the time of transfer. She +refused abdominal CT. Renal was consulted, but felt HD not +indicated today. +. +. +ROS: Negative for fevers, chills, chest pain, diarrhea, rash, +joint pains. +n/v as above. +abdominal pain unchanged from her +baseline. +dyspnea, +HA. denies visual changes, slurrring +speech, numbness, weeakness. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - 97.7 88 220/150 19 100%2L BC. +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM. +Neck: supple, no LAD, full ROM. +Lungs: CTA B, with few crackles at bases. +CV: RR, nl S1, S2 +S3, no rubs appreciated. +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation, negative [**Doctor Last Name **], no rebound, gaurding. +Ext: WWP, 1+ dp/pt pluses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +Lab Results on Admission: + +[**2142-7-3**] 11:37AM GLUCOSE-95 UREA N-40* CREAT-7.4*# SODIUM-140 +POTASSIUM-3.8 CHLORIDE-105 TOTAL CO2-23 ANION GAP-16 +ALT(SGPT)-14 AST(SGOT)-44* LD(LDH)-264* ALK PHOS-115 TOT +BILI-0.4 ALBUMIN-3.2* +WBC-3.6* RBC-2.61* HGB-7.6* HCT-23.4* MCV-90 MCH-29.0 MCHC-32.4 +RDW-18.3* +[**2142-7-3**] 11:37AM NEUTS-71.6* LYMPHS-23.0 MONOS-3.7 EOS-1.5 +BASOS-0.2 PLT COUNT-66* PT-14.0* PTT-34.5 INR(PT)-1.2* +[**2142-7-3**] 06:00PM CK-MB-5 cTropnT-0.17*CK(CPK)-58 + +[**2142-7-3**] CXR: +IMPRESSION: Unchanged moderate cardiomegaly with pulmonary +edema. Again +underlying pneumonia in the lung bases cannot be completely +excluded and +evaluation after appropriate diuresis could be performed if +pneumonia remains a clinical concern. + + +Brief Hospital Course: +24F with h/o SLE, ESRD on HD, malignant HTN, h/o SVC syndrome, +PRES, prior ICH, and recent SBO, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - On presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her PO +meds. Hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below SBP 120. She evenutally became hypotensive to SBP +of 90 which resolved on its own. She was continued on CPAP +overnight and discontinued in the am. She was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. She remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - On presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. She +did have hypoactive bowel sounds on admission. She was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with HD with plan to follow BMs +closley. Her pain improved the am of discharge and she had no +further vomiting. +. +# ESRD on HD - She is currently getting HD SaTuTh, though did +not get HD on the day of presenation. As there was no acute +indication for HD on presentation, she received HD on the +following am, day of discharge. She was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] CKD and SLE, currently +above baseline, though has h/o GIB. She received 2 unit PRBCs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of PPI [**Hospital1 **]. +. +# SLE - continue home regimen of prednisone 4mg po qdaily. +. +# h/o SVC thrombosis - pt with goal INR [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic INR. INR +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg PO 3X/WEEK +(TU,TH,SA). +. +# depression - continued on celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24H (every 24 hours). + +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) patch Transdermal +every seventy-two (72) hours. +6. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for hypertension. +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +11. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +12. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). Tablet(s) +14. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +15. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +VNA + +Discharge Diagnosis: +Primary: +hypertensive emergency +anemia, erythropoetin deficiency + +Secondary: +chronic renal failure on hemodialysis +lupus nephritis + + +Discharge Condition: +Hemodynamically stable. + + +Discharge Instructions: +You were admitted for hypertensive urgency and treated in the +intensvie care unit with IV medications to decrease your blood +pressure. You also received 2 units of blood and hemodialysis +before you were discharged home. + +It is essential that you take all of your prescribed blood +pressure medications and present regularly for your Tuesday, +Thursday, Saturday dialysis. + +Please return to the emergency department or call your primary +care physician if you develop any chest pain, shortness of +breath, fevers, or any other concerning symptoms. + +Followup Instructions: +You have the following appointment scheduled. Please contact +your provider if you are unable to make these appointments. + +Your dialysis is scheduled for Tuesday, Thursday, Saturday. + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",19,2142-07-03 14:48:00,2142-07-04 17:23:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24f with h/o sle, esrd on hd, malignant htn, h/o svc syndrome, +pres, prior ich, and recent sbo, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - on presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her po +meds. hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below sbp 120. she evenutally became hypotensive to sbp +of 90 which resolved on its own. she was continued on cpap +overnight and discontinued in the am. she was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. she remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - on presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. she +did have hypoactive bowel sounds on admission. she was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with hd with plan to follow bms +closley. her pain improved the am of discharge and she had no +further vomiting. +. +# esrd on hd - she is currently getting hd satuth, though did +not get hd on the day of presenation. as there was no acute +indication for hd on presentation, she received hd on the +following am, day of discharge. she was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] ckd and sle, currently +above baseline, though has h/o gib. she received 2 unit prbcs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of ppi [**hospital1 **]. +. +# sle - continue home regimen of prednisone 4mg po qdaily. +. +# h/o svc thrombosis - pt with goal inr [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic inr. inr +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg po 3x/week +(tu,th,sa). +. +# depression - continued on celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified iridocyclitis; Other primary cardiomyopathies; Abdominal pain, unspecified site; Other chronic pain; Nausea with vomiting; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other specified peripheral vascular diseases; Obstructive sleep apnea (adult)(pediatric); Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,174489.0,14861,2142-07-04,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",162,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,174489.0,14861,2142-07-04,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",137,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,174489.0,14861,2142-07-04,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",128,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,174489.0,14861,2142-07-04,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",103,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,174489.0,14861,2142-07-04,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",95,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,174489.0,14861,2142-07-04,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",73,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,196721.0,14863,2142-07-23,14862,131376.0,2142-07-08,Discharge summary,"Admission Date: [**2142-7-7**] Discharge Date: [**2142-7-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**Last Name (NamePattern1) 293**] +Chief Complaint: +dyspnea, Hypertension Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +admitted [**Date range (1) 43607**] after presenting for hypertensive urgency and +dyspnea for which she was started on nitroglycerin and labetalol +drips, which were weaned off in the ICU. She was also received +2U PRBCs during HD. She was discahrged home without any changes +to her medical regimen. +. +On the afternoon of [**7-4**] she notes increased dyspnea, she +therefore went to HD on Wednesday, and again on Thursday [**7-5**]. +After HD, her BP remained elevated, and she took an extra dose +of labetalol 1000mg x 1. On [**7-6**] her VNA noted SBP 250s. She +took extra doses of hydralazine, but otherwise felt well. She +then woke up this morning with HA. She took all of her BP meds +this morning, but remained with HA and SOB, thus prompting her +presentation to the ED. +. +No fevers, productive cough, taking all meds, had chronic +diarrhea that is unchanged, some n/v at baseline, no coffee +ground emesis, has some abdominal pain unchanged from baseline + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + + +Family History: +No known autoimmune disease. + +Pertinent Results: +08:00a +ALK,ALT,AST,CK,CPIS,LIP,BILI,TNT ADDED 12:29PM +141 103 29 82 AGap=13 + +3.4 28 6.5 ∆ +CK: 59 MB: Notdone Trop-T: 0.18 + +ALT: 21 AP: 126 Tbili: 0.4 Alb: +AST: 51 LDH: Dbili: TProt: +[**Doctor First Name **]: Lip: 56 + +PT: 15.0 PTT: 35.5 INR: 1.3 + + +N:69.8 L:21.9 M:5.5 E:2.5 Bas:0.3 +Hypochr: 1+ Anisocy: 2+ Macrocy: 1+ Microcy: 1+ Polychr: 1+ + + +Brief Hospital Course: +# Hypertensive Urgency - At the time of admission, the patient +denied chest pain but continued to have mild headache. She also +had resolving shortness of breath, likely secondary to +hypertension. She stated that she did take her PO meds. She +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. A sent of cardiac enzymes was sent and revealed a +CPK of 59 and a troponin of 0.18. The patient also underwent +dialysis in the ICU. After dialysis the labetalol drip was +weaned off. Overnight, SBP's ranged 109 to 182 mmHg. The +following day, her SBP's ranged 133 to 200. Ultimately, she was +discharged home on her normal medication regimen. + +# Abdominal Pain - The patient also presented complaining of +adbominal pain. She had recently been treated for SBO; however, +at the time of admit, she was without nausea or vomiting. She +had a soft abdomen, was passing flatus, and was having daily +bowel movements. She did have hypoactive bowel sounds. She was +continued of her outpatient pain regimen of PO dilaudid, +fentanyl patch, and lidoacine patch. An ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +Considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. This +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. After the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent SBO. + +# ESRD on HD - The patient gets hemodialysis on a Tu/Th/Sa +schedule. On admit, the patient was continued on her home does +of sevalemer. Renal was consulted, and the patient received +dialysis on [**7-7**] in the ICU. + +# Anemia/Pancytopenia - The patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her CKD and +SLE. On admit she was actually above baseline. She was +continued on her home does of epogen. + +# H/o Gastric Ulcer - The patient was continued on her PPI [**Hospital1 **]. + + +# SLE - The patient was continued on her home regimen of +prednisone 4mg po daily. + +# H/o SVC Thrombosis - The patient has a goal INR of [**2-13**]. +However, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic INR. On admit, her INR was +sub-therapeutic. Therefore, her warfarin was restarted at 3 mg +daily. + +# Seizure Disorder - The patient was continued on her home +regimen of keppra 1000 mg PO 3 times a week (Tu/Th/Sa). + +# Depression - The patient was continued on her home dose of +celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24HR (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +Disp:*QS Tablet(s)* Refills:*2* +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). +17. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive Urgency +Lupus Nephritis +End stage renal disease on hemodialysis +Ascites + + +Discharge Condition: +hemodynamically stable with blood pressures 130-140/70-80s. + + +Discharge Instructions: +You were evaluated and treated for you hypertension. You were +started on IV medications and transitioned to your home regimen +and received a session of hemodialysis. + +You also had an ultrasound to evaluate the fluid in your belly. +There was no evidence of blood clot contributing to the build up +of the fluid. + +Please continue to follow a low sodium diet at home and take all +of your blood pressure medications in addition to going to +dialysis. + +Followup Instructions: +You have the following appointments scheduled: +Please also keep your Tuesday/Thursday/Saturday Dialysis +schedule + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",15,2142-07-07 10:01:00,2142-07-08 18:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +# hypertensive urgency - at the time of admission, the patient +denied chest pain but continued to have mild headache. she also +had resolving shortness of breath, likely secondary to +hypertension. she stated that she did take her po meds. she +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. a sent of cardiac enzymes was sent and revealed a +cpk of 59 and a troponin of 0.18. the patient also underwent +dialysis in the icu. after dialysis the labetalol drip was +weaned off. overnight, sbps ranged 109 to 182 mmhg. the +following day, her sbps ranged 133 to 200. ultimately, she was +discharged home on her normal medication regimen. + +# abdominal pain - the patient also presented complaining of +adbominal pain. she had recently been treated for sbo; however, +at the time of admit, she was without nausea or vomiting. she +had a soft abdomen, was passing flatus, and was having daily +bowel movements. she did have hypoactive bowel sounds. she was +continued of her outpatient pain regimen of po dilaudid, +fentanyl patch, and lidoacine patch. an ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. this +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. after the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent sbo. + +# esrd on hd - the patient gets hemodialysis on a tu/th/sa +schedule. on admit, the patient was continued on her home does +of sevalemer. renal was consulted, and the patient received +dialysis on [**7-7**] in the icu. + +# anemia/pancytopenia - the patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her ckd and +sle. on admit she was actually above baseline. she was +continued on her home does of epogen. + +# h/o gastric ulcer - the patient was continued on her ppi [**hospital1 **]. + + +# sle - the patient was continued on her home regimen of +prednisone 4mg po daily. + +# h/o svc thrombosis - the patient has a goal inr of [**2-13**]. +however, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic inr. on admit, her inr was +sub-therapeutic. therefore, her warfarin was restarted at 3 mg +daily. + +# seizure disorder - the patient was continued on her home +regimen of keppra 1000 mg po 3 times a week (tu/th/sa). + +# depression - the patient was continued on her home dose of +celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Unspecified iridocyclitis; ; Other ascites; Other chronic pain; Abdominal pain, unspecified site; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,131376.0,14862,2142-07-08,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",51,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,131376.0,14862,2142-07-08,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",33,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,131376.0,14862,2142-07-08,14860,136572.0,2142-06-20,Discharge summary,"Admission Date: [**2142-6-18**] Discharge Date: [**2142-6-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2145**] +Chief Complaint: +Acute Onset Dyspnea + +Major Surgical or Invasive Procedure: +Dialysis + + +History of Present Illness: +Please see MICU note for full details. In brief this is a 24 +y.o. woman with SLE, ESRD on HD, hx malignant HTN, h/o SVC +syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, frequently admitted +with hypertensive urgency/emergency who was admitted with acute +onset dyspnea after 2 weeks without dialysis given to unable to +get transportation ? despite Dr. [**Last Name (STitle) 7473**] attempting to arrange +transport for her (? refused to come). She was admitted +therefore on [**6-18**] to micu with VS: T 100.4 HR 108 BP 240/180 RR +28 POx100 RA. She was treated with nitro gtt, labetolol gtt and +dilaudid-these gtts were stopped at 0700. In the micu she was +dialyzed with 1.7L fluid removal (though + 300cc given +tranfusion). Her SOB is improved. Her hct was also noted to be +low (18->from 22 [**2142-6-5**]) so transfused 2 units PRBC's, recent +EGD with gastric ulcer [**5-29**], guaiac negative in ED, no BM in +unit, hemolysis w/u negative. BP in icu 140/106 currently but of +note was hypotensive on HD to 86/62. She notes sob improved +rapidly on arrival. + +ROS: Currently she has no complaints. She notes at home her +abdominal pain is at baseline for her, felt mid epigastric, for +which she takes dilaudid 4mg up to [**Hospital1 **]. She has been getting HD +via right femoral catheter which is not painful, no discharge +from the sight. She denies HA, visual changes, cough, chest pain +or pressure, orthostatic changes, palpitations, nausea, +vomiting, constipation, diarrhea, melena, brbpr, dysuria, +hematuria, rash, swelling, orthopnea, pnd. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - T: 97.7, BP: 140/99 P: 88 R: 19 O2: 98% on RA +General: Sleeping comfortably but awakens easily, alert, +oriented x3 +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM, moon facies +Neck: supple, JVP flat, no LAD, full ROM, left EJ in place +Lungs: coarse BS throughout, no W/R/R, no decreased BS at bases + +CV: S1, S2 nl, no m/r/g appreciated +Abdomen: Firm, non-tender to palpation, no masses or +organomegally +Ext: Warm, well perfused, 1+ DP/PT, no clubbing, cyanosis or +edema +Neuro: a&o x3, motor [**5-15**] UE/LE bilaterally + + +Pertinent Results: +[**2142-6-18**] 05:28PM HCT-26.0*# +[**2142-6-18**] 11:38AM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-NORMAL MICROCYT-OCCASIONAL POLYCHROM-NORMAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-6-18**] 05:04AM GLUCOSE-85 UREA N-72* CREAT-10.4* SODIUM-139 +POTASSIUM-5.5* CHLORIDE-109* TOTAL CO2-14* ANION GAP-22* +[**2142-6-18**] 05:04AM LD(LDH)-264* TOT BILI-0.2 +[**2142-6-18**] 05:04AM CALCIUM-6.6* PHOSPHATE-6.5* MAGNESIUM-1.6 +[**2142-6-18**] 05:04AM HAPTOGLOB-142 +[**2142-6-18**] 05:04AM WBC-3.4* RBC-1.93* HGB-5.8* HCT-17.0* MCV-88 +MCH-30.0 MCHC-34.2 RDW-18.4* +[**2142-6-18**] 05:04AM PLT COUNT-97* +[**2142-6-18**] 01:34AM GLUCOSE-84 UREA N-70* CREAT-10.5*# SODIUM-136 +POTASSIUM-5.6* CHLORIDE-108 TOTAL CO2-14* ANION GAP-20 +[**2142-6-18**] 01:34AM estGFR-Using this +[**2142-6-18**] 01:34AM ALT(SGPT)-10 AST(SGOT)-39 ALK PHOS-108 TOT +BILI-0.2 +[**2142-6-18**] 01:34AM LIPASE-115* +[**2142-6-18**] 01:34AM ALBUMIN-3.2* CALCIUM-6.6* PHOSPHATE-6.8* +MAGNESIUM-1.7 +[**2142-6-18**] 01:34AM WBC-4.5 RBC-2.08* HGB-6.0* HCT-18.3* MCV-88 +MCH-28.6 MCHC-32.5 RDW-18.6* +[**2142-6-18**] 01:34AM NEUTS-78.5* LYMPHS-16.5* MONOS-3.0 EOS-1.4 +BASOS-0.6 +[**2142-6-18**] 01:34AM PLT COUNT-104* +[**2142-6-18**] 01:34AM PT-15.0* PTT-33.6 INR(PT)-1.3* + +Brief Hospital Course: +# Dyspnea: Pt's dypsnea improved on admission to the ED prior to +HD. Based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. Upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# Anemia: Pt's baseline 1 month ago noted to be low 30s, since +then her Hct has trended down to 22 several week prior to +admission. As she missed dialysis she was not able to reserve +her Eopgen which likely complicated her anemia. Pt underwent +hemolysis workup in the ICU which was ultimately negative. She +was given several units of PRBC and bumped her Hct +appropriately. She was noted to be guaiac negative on +examination. + +# Hypertension: Pt was initially admitted with hypertension. +Following transition to the floor she was placed on her home +regimen. She was noted to be hypotensive in dialysis which is +likely due to her being on Labetalol, Nitro gtt on dialysis. Pt +was discharged on her home BP regimen with follow up with her +nephrologist. + +# Chronic Abdominal Pain: Pt had noted some intermittent +abdominal pain which has been chronic. Lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. Pt was able to tolerate a PO diet prior to her +discharge. Pt was continued on her outpatient regimen of +Dilaudid, Fentanyl patch, Neurontin. + +# GE junction Ulcer: Pt was continued on her PPI regimen [**Hospital1 **]. + +# SLE: Pt was continued on her home regimen of Prednisone 4mg +daily + +# History of DVT: Pt had a sub-therapeutic INR on admission. She +was discharged on Warfarin 3mg daily. + +# ESRD on HD: Pt was admitted for dyspnea in the setting of +missing 2 weeks of HD. The renal team followed Ms. [**Known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. Pt was continued on Sevelamer and +Epogen. + +# Seizure D/O: Pt was continued on her home regimen of keppra. + +# Depression: Pt was continued on her home regimen of Celexa. + + +Medications on Admission: +1. Nifedipine 90 mg Tablet Sustained Release PO QAM +2. Nifedipine 60 mg Tablet Sustained Release PO QHS +3. Lidocaine 5 % transdermal one daily +4. Aliskiren 150 mg PO BID +5. Citalopram 20 mg PO DAILY (Daily). +6. Fentanyl 25 mcg/hr Patch Q72H (every 72 hours). +7. Prednisone 4mg PO DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Transdermal QSAT +9. Clonidine 0.3 mg/24 hr Patch Weekly Transdermal QSAT +10. Sevelamer HCl 400 mg Four (4) Tablet PO TID W/MEALS +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +13. Hydralazine 100 mg PO Q8H +14. Hydromorphone 2 mg 1-2 Tablets PO Q6H as needed for pain. +15. Pantoprazole 40 mg PO Q12H +16. LeVETiracetam 1,000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24 H (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: Malignant HTN, ESRD on HD, Shortness of breath +Secondary: Lupus + + +Discharge Condition: +Stable, afebrile + + +Discharge Instructions: +You were admitted to the hospital after you noticed some +shortness of breath. Whilst in the hospital you were noted to +have a low blood level (anemia) and you some fluid in your +lungs. We think your blood level was low because you were not +receiving your Epo shots, we think the fluid is from not +receiving dialysis. Before you were discharged from the hospital +your breathing was better. + +We recommend that you continue going to dialysis. + +We made no changes to your medications. + +If you notice any fevers, chills, nausea, vomiting, shortness of +breath, lightheadedness please return to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 +Provider: [**First Name4 (NamePattern1) **] [**Name Initial (NameIs) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-27**] 2:00 + + + [**Name6 (MD) **] [**Name8 (MD) **] MD [**MD Number(2) 2158**] + +",18,2142-06-18 03:11:00,2142-06-20 16:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ANEMIA," +# dyspnea: pts dypsnea improved on admission to the ed prior to +hd. based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# anemia: pts baseline 1 month ago noted to be low 30s, since +then her hct has trended down to 22 several week prior to +admission. as she missed dialysis she was not able to reserve +her eopgen which likely complicated her anemia. pt underwent +hemolysis workup in the icu which was ultimately negative. she +was given several units of prbc and bumped her hct +appropriately. she was noted to be guaiac negative on +examination. + +# hypertension: pt was initially admitted with hypertension. +following transition to the floor she was placed on her home +regimen. she was noted to be hypotensive in dialysis which is +likely due to her being on labetalol, nitro gtt on dialysis. pt +was discharged on her home bp regimen with follow up with her +nephrologist. + +# chronic abdominal pain: pt had noted some intermittent +abdominal pain which has been chronic. lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. pt was able to tolerate a po diet prior to her +discharge. pt was continued on her outpatient regimen of +dilaudid, fentanyl patch, neurontin. + +# ge junction ulcer: pt was continued on her ppi regimen [**hospital1 **]. + +# sle: pt was continued on her home regimen of prednisone 4mg +daily + +# history of dvt: pt had a sub-therapeutic inr on admission. she +was discharged on warfarin 3mg daily. + +# esrd on hd: pt was admitted for dyspnea in the setting of +missing 2 weeks of hd. the renal team followed ms. [**known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. pt was continued on sevelamer and +epogen. + +# seizure d/o: pt was continued on her home regimen of keppra. + +# depression: pt was continued on her home regimen of celexa. + + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Anemia of other chronic disease; Hyperpotassemia; Systemic lupus erythematosus; Abdominal pain, other specified site; Other chronic pain; Hypotension, unspecified; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Depressive disorder, not elsewhere classified; Personal history of venous thrombosis and embolism; Noncompliance with renal dialysis]" +109,131376.0,14862,2142-07-08,14861,174489.0,2142-07-04,Discharge summary,"Admission Date: [**2142-7-3**] Discharge Date: [**2142-7-4**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2817**] +Chief Complaint: +dyspnea, hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +discharged on [**7-1**] after presenting for hypertensive urgency and +dyspnea for which she received iv medication in the ED, but was +otherwised managed with oral antihypertensives and CPAP. +. +She was doing well until the evening of [**7-2**] when she notes the +gradual onset of dyspnea. She denied f/c/cp/ha/abd +pain/diarrhea, or constipation. She was having regular, soft, +daily BMs. +. +On [**7-3**] she awoke, and describes n/v x 2, with increasing +dyspnea, and headache. She did not want to wait until dialysis +at 4PM and therefore presented to [**Hospital1 18**]. +. +In ED VS= 97.7 [**Telephone/Fax (2) 43606**] 100%RA. Labs were notable for HCT +23, PLT 66, WBC 3.3, all roughly at baseline. CXR without acute +process, ECG unchanged from prior. No UA sent, though she does +make some urine. She was started on nitro gtt with modest +improvement of SBPs to 210s, then labetalol 20mg iv x1 followed +by labetalol gtt with BP 221/130 at the time of transfer. She +refused abdominal CT. Renal was consulted, but felt HD not +indicated today. +. +. +ROS: Negative for fevers, chills, chest pain, diarrhea, rash, +joint pains. +n/v as above. +abdominal pain unchanged from her +baseline. +dyspnea, +HA. denies visual changes, slurrring +speech, numbness, weeakness. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - 97.7 88 220/150 19 100%2L BC. +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM. +Neck: supple, no LAD, full ROM. +Lungs: CTA B, with few crackles at bases. +CV: RR, nl S1, S2 +S3, no rubs appreciated. +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation, negative [**Doctor Last Name **], no rebound, gaurding. +Ext: WWP, 1+ dp/pt pluses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +Lab Results on Admission: + +[**2142-7-3**] 11:37AM GLUCOSE-95 UREA N-40* CREAT-7.4*# SODIUM-140 +POTASSIUM-3.8 CHLORIDE-105 TOTAL CO2-23 ANION GAP-16 +ALT(SGPT)-14 AST(SGOT)-44* LD(LDH)-264* ALK PHOS-115 TOT +BILI-0.4 ALBUMIN-3.2* +WBC-3.6* RBC-2.61* HGB-7.6* HCT-23.4* MCV-90 MCH-29.0 MCHC-32.4 +RDW-18.3* +[**2142-7-3**] 11:37AM NEUTS-71.6* LYMPHS-23.0 MONOS-3.7 EOS-1.5 +BASOS-0.2 PLT COUNT-66* PT-14.0* PTT-34.5 INR(PT)-1.2* +[**2142-7-3**] 06:00PM CK-MB-5 cTropnT-0.17*CK(CPK)-58 + +[**2142-7-3**] CXR: +IMPRESSION: Unchanged moderate cardiomegaly with pulmonary +edema. Again +underlying pneumonia in the lung bases cannot be completely +excluded and +evaluation after appropriate diuresis could be performed if +pneumonia remains a clinical concern. + + +Brief Hospital Course: +24F with h/o SLE, ESRD on HD, malignant HTN, h/o SVC syndrome, +PRES, prior ICH, and recent SBO, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - On presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her PO +meds. Hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below SBP 120. She evenutally became hypotensive to SBP +of 90 which resolved on its own. She was continued on CPAP +overnight and discontinued in the am. She was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. She remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - On presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. She +did have hypoactive bowel sounds on admission. She was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with HD with plan to follow BMs +closley. Her pain improved the am of discharge and she had no +further vomiting. +. +# ESRD on HD - She is currently getting HD SaTuTh, though did +not get HD on the day of presenation. As there was no acute +indication for HD on presentation, she received HD on the +following am, day of discharge. She was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] CKD and SLE, currently +above baseline, though has h/o GIB. She received 2 unit PRBCs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of PPI [**Hospital1 **]. +. +# SLE - continue home regimen of prednisone 4mg po qdaily. +. +# h/o SVC thrombosis - pt with goal INR [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic INR. INR +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg PO 3X/WEEK +(TU,TH,SA). +. +# depression - continued on celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24H (every 24 hours). + +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) patch Transdermal +every seventy-two (72) hours. +6. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for hypertension. +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +11. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +12. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). Tablet(s) +14. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +15. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +VNA + +Discharge Diagnosis: +Primary: +hypertensive emergency +anemia, erythropoetin deficiency + +Secondary: +chronic renal failure on hemodialysis +lupus nephritis + + +Discharge Condition: +Hemodynamically stable. + + +Discharge Instructions: +You were admitted for hypertensive urgency and treated in the +intensvie care unit with IV medications to decrease your blood +pressure. You also received 2 units of blood and hemodialysis +before you were discharged home. + +It is essential that you take all of your prescribed blood +pressure medications and present regularly for your Tuesday, +Thursday, Saturday dialysis. + +Please return to the emergency department or call your primary +care physician if you develop any chest pain, shortness of +breath, fevers, or any other concerning symptoms. + +Followup Instructions: +You have the following appointment scheduled. Please contact +your provider if you are unable to make these appointments. + +Your dialysis is scheduled for Tuesday, Thursday, Saturday. + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",4,2142-07-03 14:48:00,2142-07-04 17:23:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24f with h/o sle, esrd on hd, malignant htn, h/o svc syndrome, +pres, prior ich, and recent sbo, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - on presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her po +meds. hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below sbp 120. she evenutally became hypotensive to sbp +of 90 which resolved on its own. she was continued on cpap +overnight and discontinued in the am. she was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. she remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - on presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. she +did have hypoactive bowel sounds on admission. she was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with hd with plan to follow bms +closley. her pain improved the am of discharge and she had no +further vomiting. +. +# esrd on hd - she is currently getting hd satuth, though did +not get hd on the day of presenation. as there was no acute +indication for hd on presentation, she received hd on the +following am, day of discharge. she was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] ckd and sle, currently +above baseline, though has h/o gib. she received 2 unit prbcs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of ppi [**hospital1 **]. +. +# sle - continue home regimen of prednisone 4mg po qdaily. +. +# h/o svc thrombosis - pt with goal inr [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic inr. inr +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg po 3x/week +(tu,th,sa). +. +# depression - continued on celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified iridocyclitis; Other primary cardiomyopathies; Abdominal pain, unspecified site; Other chronic pain; Nausea with vomiting; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other specified peripheral vascular diseases; Obstructive sleep apnea (adult)(pediatric); Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,174489.0,14861,2142-07-04,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",165,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,155726.0,14864,2142-08-16,14862,131376.0,2142-07-08,Discharge summary,"Admission Date: [**2142-7-7**] Discharge Date: [**2142-7-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**Last Name (NamePattern1) 293**] +Chief Complaint: +dyspnea, Hypertension Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +admitted [**Date range (1) 43607**] after presenting for hypertensive urgency and +dyspnea for which she was started on nitroglycerin and labetalol +drips, which were weaned off in the ICU. She was also received +2U PRBCs during HD. She was discahrged home without any changes +to her medical regimen. +. +On the afternoon of [**7-4**] she notes increased dyspnea, she +therefore went to HD on Wednesday, and again on Thursday [**7-5**]. +After HD, her BP remained elevated, and she took an extra dose +of labetalol 1000mg x 1. On [**7-6**] her VNA noted SBP 250s. She +took extra doses of hydralazine, but otherwise felt well. She +then woke up this morning with HA. She took all of her BP meds +this morning, but remained with HA and SOB, thus prompting her +presentation to the ED. +. +No fevers, productive cough, taking all meds, had chronic +diarrhea that is unchanged, some n/v at baseline, no coffee +ground emesis, has some abdominal pain unchanged from baseline + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + + +Family History: +No known autoimmune disease. + +Pertinent Results: +08:00a +ALK,ALT,AST,CK,CPIS,LIP,BILI,TNT ADDED 12:29PM +141 103 29 82 AGap=13 + +3.4 28 6.5 ∆ +CK: 59 MB: Notdone Trop-T: 0.18 + +ALT: 21 AP: 126 Tbili: 0.4 Alb: +AST: 51 LDH: Dbili: TProt: +[**Doctor First Name **]: Lip: 56 + +PT: 15.0 PTT: 35.5 INR: 1.3 + + +N:69.8 L:21.9 M:5.5 E:2.5 Bas:0.3 +Hypochr: 1+ Anisocy: 2+ Macrocy: 1+ Microcy: 1+ Polychr: 1+ + + +Brief Hospital Course: +# Hypertensive Urgency - At the time of admission, the patient +denied chest pain but continued to have mild headache. She also +had resolving shortness of breath, likely secondary to +hypertension. She stated that she did take her PO meds. She +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. A sent of cardiac enzymes was sent and revealed a +CPK of 59 and a troponin of 0.18. The patient also underwent +dialysis in the ICU. After dialysis the labetalol drip was +weaned off. Overnight, SBP's ranged 109 to 182 mmHg. The +following day, her SBP's ranged 133 to 200. Ultimately, she was +discharged home on her normal medication regimen. + +# Abdominal Pain - The patient also presented complaining of +adbominal pain. She had recently been treated for SBO; however, +at the time of admit, she was without nausea or vomiting. She +had a soft abdomen, was passing flatus, and was having daily +bowel movements. She did have hypoactive bowel sounds. She was +continued of her outpatient pain regimen of PO dilaudid, +fentanyl patch, and lidoacine patch. An ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +Considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. This +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. After the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent SBO. + +# ESRD on HD - The patient gets hemodialysis on a Tu/Th/Sa +schedule. On admit, the patient was continued on her home does +of sevalemer. Renal was consulted, and the patient received +dialysis on [**7-7**] in the ICU. + +# Anemia/Pancytopenia - The patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her CKD and +SLE. On admit she was actually above baseline. She was +continued on her home does of epogen. + +# H/o Gastric Ulcer - The patient was continued on her PPI [**Hospital1 **]. + + +# SLE - The patient was continued on her home regimen of +prednisone 4mg po daily. + +# H/o SVC Thrombosis - The patient has a goal INR of [**2-13**]. +However, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic INR. On admit, her INR was +sub-therapeutic. Therefore, her warfarin was restarted at 3 mg +daily. + +# Seizure Disorder - The patient was continued on her home +regimen of keppra 1000 mg PO 3 times a week (Tu/Th/Sa). + +# Depression - The patient was continued on her home dose of +celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24HR (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +Disp:*QS Tablet(s)* Refills:*2* +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). +17. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive Urgency +Lupus Nephritis +End stage renal disease on hemodialysis +Ascites + + +Discharge Condition: +hemodynamically stable with blood pressures 130-140/70-80s. + + +Discharge Instructions: +You were evaluated and treated for you hypertension. You were +started on IV medications and transitioned to your home regimen +and received a session of hemodialysis. + +You also had an ultrasound to evaluate the fluid in your belly. +There was no evidence of blood clot contributing to the build up +of the fluid. + +Please continue to follow a low sodium diet at home and take all +of your blood pressure medications in addition to going to +dialysis. + +Followup Instructions: +You have the following appointments scheduled: +Please also keep your Tuesday/Thursday/Saturday Dialysis +schedule + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",39,2142-07-07 10:01:00,2142-07-08 18:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +# hypertensive urgency - at the time of admission, the patient +denied chest pain but continued to have mild headache. she also +had resolving shortness of breath, likely secondary to +hypertension. she stated that she did take her po meds. she +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. a sent of cardiac enzymes was sent and revealed a +cpk of 59 and a troponin of 0.18. the patient also underwent +dialysis in the icu. after dialysis the labetalol drip was +weaned off. overnight, sbps ranged 109 to 182 mmhg. the +following day, her sbps ranged 133 to 200. ultimately, she was +discharged home on her normal medication regimen. + +# abdominal pain - the patient also presented complaining of +adbominal pain. she had recently been treated for sbo; however, +at the time of admit, she was without nausea or vomiting. she +had a soft abdomen, was passing flatus, and was having daily +bowel movements. she did have hypoactive bowel sounds. she was +continued of her outpatient pain regimen of po dilaudid, +fentanyl patch, and lidoacine patch. an ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. this +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. after the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent sbo. + +# esrd on hd - the patient gets hemodialysis on a tu/th/sa +schedule. on admit, the patient was continued on her home does +of sevalemer. renal was consulted, and the patient received +dialysis on [**7-7**] in the icu. + +# anemia/pancytopenia - the patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her ckd and +sle. on admit she was actually above baseline. she was +continued on her home does of epogen. + +# h/o gastric ulcer - the patient was continued on her ppi [**hospital1 **]. + + +# sle - the patient was continued on her home regimen of +prednisone 4mg po daily. + +# h/o svc thrombosis - the patient has a goal inr of [**2-13**]. +however, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic inr. on admit, her inr was +sub-therapeutic. therefore, her warfarin was restarted at 3 mg +daily. + +# seizure disorder - the patient was continued on her home +regimen of keppra 1000 mg po 3 times a week (tu/th/sa). + +# depression - the patient was continued on her home dose of +celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Unspecified iridocyclitis; ; Other ascites; Other chronic pain; Abdominal pain, unspecified site; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,155726.0,14864,2142-08-16,14863,196721.0,2142-07-23,Discharge summary,"Admission Date: [**2142-7-12**] Discharge Date: [**2142-7-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Dyspnea, hypertension + +Major Surgical or Invasive Procedure: +1. Ultrasound Guided Tap +2. Venogram + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old female with a history of SLE, ESRD on +HD, h/o malignant HTN, SVC syndrome, PRES, prior ICH, with +frequent admission for hypertensive urgency/emergency, with +chronic abdominal pain that presented to the ED [**7-12**] with +critically high blood pressure and dyspnea. She was recently +discharged on [**7-8**] for hypertensive urgency and dyspnea. She +was treated with labetolol gtt, [**Month/Year (2) 2286**], and her home +medications with improvement of her BP. She was discharged home +in stable condition on [**7-8**]. She had been doing well at home, +but missed her HD session on [**7-10**] due to transportation issues. +She has been taking her medications without any difficulty. On +the morning of admission, she noted increase dyspnea, and had a +dry cough, although this is not particularly new. She presented +to the ER for dyspnea. She continues to have the chronic +abdominal pain which is unchanged, and is controlled right now. + + +In the emergency department, VS= 98.1, 240/140, 128, 30, 96%RA. +On initial evaluation, she was noted to have SBP 70s on the +right arm, 240s on the left arm. She did not complain of any +pain. She underwent CTA torso to eval for dissection which was +negative for dissection or PE. The imaging showed persistent SVC +thrombus. There was also note of bilateral ground glass and +nodularities therefore was given levofloxacin 750 mg IV x 1. She +was given labetalol IV, then started on a labetalol gtt. Her BP +remained elevated, therefore she was transferred to the ICU for +BP control and then [**Month/Year (2) 2286**]. She was also given dilaudid 1 mg +IV x 1 as well. + +Ms. [**Known lastname **] was taken to the MICU and treated for malignant +hypertension. She was given hemodialysis and her blood pressure +stabilized. She was transferred to the medical floor. She +continued to receive [**Known lastname 2286**] Tuesday, Thursday, and Saturday. +On [**7-16**], she had a paracentesis of her abdomen. She is +complaining of focal tenderness around the point of insertion. +On [**7-17**], she was transferred back to the MICU because of stridor +that was treated with Heliox. She was stabilized, and came back +to the floor on [**7-19**]. On [**7-19**], Ms. [**Known lastname **] had a venogram. On +[**7-23**], an angiography intervention for an occlusion of her left +brachiocephalic vein was discontinued because her occlusion was +not as drastic as prior imaging indicated when tested with a 22 +gauge needle. Ms. [**Known lastname **] was discharged on [**7-23**] with stable +blood pressures and abdominal pain controlled. + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD 3. Malignant hypertension with baseline SBP's +180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, + +Neck: supple, no LAD +Lungs: CTA B, with few crackles at bases. +CV: RRR, S1, S2 +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation +Ext: palpable DP/PT pulses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +[**2142-7-22**] 07:50AM BLOOD WBC-2.8* RBC-2.51* Hgb-7.3* Hct-23.1* +MCV-92 MCH-29.1 MCHC-31.8 RDW-21.1* Plt Ct-134* +[**2142-7-21**] 10:30AM BLOOD WBC-3.5* RBC-2.36* Hgb-6.8* Hct-21.6* +MCV-92 MCH-28.9 MCHC-31.6 RDW-20.5* Plt Ct-121* +[**2142-7-22**] 07:50AM BLOOD PT-14.7* PTT-35.0 INR(PT)-1.3* +[**2142-7-22**] 07:50AM BLOOD Glucose-154* UreaN-20 Creat-4.4* Na-138 +K-4.0 Cl-103 HCO3-23 AnGap-16 +[**2142-7-21**] 10:30AM BLOOD Vanco-17.8 +[**2142-7-20**] 09:35AM BLOOD WBC-3.8* RBC-2.39* Hgb-7.0* Hct-21.6* +MCV-90 MCH-29.2 MCHC-32.4 RDW-19.8* Plt Ct-120* +[**2142-7-19**] 12:30PM BLOOD WBC-3.6* RBC-2.49* Hgb-7.0* Hct-22.5* +MCV-90 MCH-28.3 MCHC-31.3 RDW-18.8* Plt Ct-121* +[**2142-7-20**] 09:35AM BLOOD Plt Ct-120* +[**2142-7-20**] 09:35AM BLOOD PT-19.7* PTT-38.4* INR(PT)-1.8* +[**2142-7-19**] 12:30PM BLOOD Plt Ct-121* +[**2142-7-19**] 12:30PM BLOOD PT-29.5* PTT-43.9* INR(PT)-2.9* +[**2142-7-20**] 09:35AM BLOOD Glucose-90 UreaN-19 Creat-4.2*# Na-138 +K-4.2 Cl-102 HCO3-25 AnGap-15 +[**2142-7-19**] 12:30PM BLOOD Glucose-72 UreaN-34* Creat-6.0*# Na-137 +K-4.5 Cl-102 HCO3-24 AnGap-16 +[**2142-7-19**] 12:30PM BLOOD Calcium-8.2* Phos-4.6* Mg-1.6 +[**2142-7-18**] 05:44AM BLOOD Calcium-8.9 Phos-5.1* Mg-1.7 +[**2142-7-12**] 12:27PM BLOOD [**Doctor First Name **]-POSITIVE * Titer-1:80 [**Last Name (un) **] +[**2142-7-12**] 12:27PM BLOOD C3-69* C4-17 +[**2142-7-19**] 12:30PM BLOOD Vanco-16.7 +[**2142-7-17**] 08:57AM BLOOD Vanco-15.9 +[**2142-7-14**] 04:16AM BLOOD Vanco-19.2 +[**2142-7-17**] 07:27AM BLOOD Type-ART pO2-66* pCO2-52* pH-7.30* +calTCO2-27 Base XS--1 +[**2142-7-12**] 02:06PM BLOOD Lactate-1.0 + + +Brief Hospital Course: +24 y/o female with h/o SLE, ESRD on HD, malignant HTN, h/o SVC +syndrome, PRES, prior ICH, and recent SBO, presented to ED on +[**7-12**] for dyspnea and hypertensive urgency. + +1. hypertensive urgency - pt presented to ER with SBP in 240s +and c/o dyspnea. Her blood pressures were reported as unequal +and CTA in ER was done. This study showed no signs of +dissection. Pt's blood pressure was controlled with labetalol +gtt. At time of transfer, she denied CP and SOB. CE's were +flat. She was started on her home BP regimen of oral labetalol +on [**2142-7-15**], and nifedipine/hydralazine/aliskerin soon after +admission. Pt was also continued on her HD regimen for ESRD, +for volume control. +. +2. angioedema - pt developed facial swelling and shortness of +breath while on medical floor. She was taken to ICU and +responded favorably to Heliox. Patient returned to floor and +has been comfortably breathing since. Given history of SVC, +venogram was ordered that did not indicate a complete occlusion +of the left brachiocephalic vein, as previously thought, with +help of 22 gauge needle. + +3. cough: pt presented with chronic cough/dyspnea without +fevers. Chest CT revealed bilateral infiltrates and +nodularities, noted possibly infectious vs edema. Pt was started +on vanc/zosyn given recent hospitalization, brief temp spike, +and pulm infiltrates. Abx were stopped after cultures were neg. +At time of transfer, pt's dyspnea was largely resolved and these +findings were felt to be more consistent with edema given +hypertensive urgency. +. +4. chronic abdominal pain - pt has had chronic abdominal pain, +which was well controlled at time of transfer. She was continued +on her current outpt pain regimen of po dilaudid, fentanyl +patch, lidoacine patch. Her LFTs and lipase were wnl. She had no +signs of SBO. +. +5. bacteremia - GPC in pairs and clusters; started on vanco on +[**2142-7-12**]. +. +6. Ascites - unclear etiology and new findings for her. Pt is +to get workup with liver team as outpatient. Her [**Date Range 2286**] seems +to have slightly improved this finding. Her coags were +unremarkable. She was seen by Hepatology in house who did not +have any specific recommendations at this time but asked to see +her in follow up as an outpatient. +. +7. ESRD on HD - HD SaTuTh,. Pt was continued on her HD regimen +while in house. Sevelamer was continued as well. +. +8. anemia/pancytopenia - chronic anemia, baseline pancytopenia, +likely [**2-12**] CKD and SLE, currently above baseline, though has h/o +GIB. Pt's pancytopenia remained stable; C3 and C4 studies were +performed and it was felt that her SLE was not active at this +time. Guiac stools were neg. EPO was continued at HD. +. +9. h/o gastric ulcer - PPI was continued throughout +hospitalization. +. +10. SLE - pt was continued on home regimen of prednisone 4mg po +qdaily. +. +11. h/o SVC thrombosis - patient's warfarin was discontinued +after discussion with Dr. [**Last Name (STitle) 4883**]. She frequently is outside +of therapeutic range on this medication and given the suspected +problems with medication compliance, it was felt it was safer to +discontinue it altogether. +. +12. seizure disorder - pt was continued on home regimen keppra +1000 mg PO 3X/WEEK (TU,TH,SA). +. +13. depression - pt was continued on her home celexa. +. + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Protonix 40 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO every twelve (12) hours. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QTHUR (every Thursday). +3. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO at bedtime. +4. Nifedipine 30 mg Tablet Sustained Release Sig: Three (3) +Tablet Sustained Release PO QAM (once a day (in the morning)). +5. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +8. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +9. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +10. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal every Thursday. +11. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +12. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day): Please hold if systolic blood pressure < 100 or HR < 55. + +14. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +15. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). +16. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +17. Vancomycin 500 mg Recon Soln Sig: One (1) Recon Soln +Intravenous HD PROTOCOL (HD Protochol). +18. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for Constipation. +Disp:*60 Tablet(s)* Refills:*2* +19. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +Disp:*60 Capsule(s)* Refills:*2* +20. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every six (6) hours +as needed for pain: do not drive or operate heavy machinery with +this medication as it can cause drowsiness. +Disp:*20 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Malignant Hypertension +Angioedema +Ascites +End Stage Renal Disease + +Secondary: +Chronic Abdominal Pain +Anemia/Pancytopenia +Lupus +Gastric Ulcer +SVC Thrombosis +Seizure Disorder +Depression + + +Discharge Condition: +Hemodynamically stable with blood pressures 130-140 / 60-90 + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] on [**2142-7-12**] because of critically high +blood pressure. While here, you were given IV antihypertensive +medications, and then you were switched to antihypertnsive +medications by mouth. You received multiple sessions of +hemodialysis. You had a distended, tender belly, and you +underwent a ultrasound guided tap to remove the fluid in your +abdomen. On [**2142-7-17**], you developed throat and facial swelling, +and you were transferred from the medical floor to the ICU. You +were given medication to help open your airway; you were +stabilized and went to hemodialysis several times. You were +transferred back to the medical floor. You had a venogram on +[**2142-7-20**], and the results at this time are still pending. + +You had blood cultures drawn that were positive for bacteria. +You received IV antibiotics while at hemodialysis. You will +continue to receive these antibiotics at your appointments. + +Please keep all of your medical appointments. + +Please go to the nearest emergency room if you experience any of +the following: + +1. Chest Pain +2. Headaches +3. Lightheadedness +4. Changes in vision +5. Nausea and Vomiting + + +Followup Instructions: +Please continue your regular hemodialysis schedule. + +You have the following appointments scheduled. Please call if +you need to cancel or change your appointments. + +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-7-21**] +12:00 + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 + +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +Completed by:[**2142-7-24**]",24,2142-07-12 15:27:00,2142-07-23 18:41:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,SHORTNESS OF BREATH," +24 y/o female with h/o sle, esrd on hd, malignant htn, h/o svc +syndrome, pres, prior ich, and recent sbo, presented to ed on +[**7-12**] for dyspnea and hypertensive urgency. + +1. hypertensive urgency - pt presented to er with sbp in 240s +and c/o dyspnea. her blood pressures were reported as unequal +and cta in er was done. this study showed no signs of +dissection. pts blood pressure was controlled with labetalol +gtt. at time of transfer, she denied cp and sob. ces were +flat. she was started on her home bp regimen of oral labetalol +on [**2142-7-15**], and nifedipine/hydralazine/aliskerin soon after +admission. pt was also continued on her hd regimen for esrd, +for volume control. +. +2. angioedema - pt developed facial swelling and shortness of +breath while on medical floor. she was taken to icu and +responded favorably to heliox. patient returned to floor and +has been comfortably breathing since. given history of svc, +venogram was ordered that did not indicate a complete occlusion +of the left brachiocephalic vein, as previously thought, with +help of 22 gauge needle. + +3. cough: pt presented with chronic cough/dyspnea without +fevers. chest ct revealed bilateral infiltrates and +nodularities, noted possibly infectious vs edema. pt was started +on vanc/zosyn given recent hospitalization, brief temp spike, +and pulm infiltrates. abx were stopped after cultures were neg. +at time of transfer, pts dyspnea was largely resolved and these +findings were felt to be more consistent with edema given +hypertensive urgency. +. +4. chronic abdominal pain - pt has had chronic abdominal pain, +which was well controlled at time of transfer. she was continued +on her current outpt pain regimen of po dilaudid, fentanyl +patch, lidoacine patch. her lfts and lipase were wnl. she had no +signs of sbo. +. +5. bacteremia - gpc in pairs and clusters; started on vanco on +[**2142-7-12**]. +. +6. ascites - unclear etiology and new findings for her. pt is +to get workup with liver team as outpatient. her [**date range 2286**] seems +to have slightly improved this finding. her coags were +unremarkable. she was seen by hepatology in house who did not +have any specific recommendations at this time but asked to see +her in follow up as an outpatient. +. +7. esrd on hd - hd satuth,. pt was continued on her hd regimen +while in house. sevelamer was continued as well. +. +8. anemia/pancytopenia - chronic anemia, baseline pancytopenia, +likely [**2-12**] ckd and sle, currently above baseline, though has h/o +gib. pts pancytopenia remained stable; c3 and c4 studies were +performed and it was felt that her sle was not active at this +time. guiac stools were neg. epo was continued at hd. +. +9. h/o gastric ulcer - ppi was continued throughout +hospitalization. +. +10. sle - pt was continued on home regimen of prednisone 4mg po +qdaily. +. +11. h/o svc thrombosis - patients warfarin was discontinued +after discussion with dr. [**last name (stitle) 4883**]. she frequently is outside +of therapeutic range on this medication and given the suspected +problems with medication compliance, it was felt it was safer to +discontinue it altogether. +. +12. seizure disorder - pt was continued on home regimen keppra +1000 mg po 3x/week (tu,th,sa). +. +13. depression - pt was continued on her home celexa. +. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other ascites; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Other primary cardiomyopathies; Unspecified disease of pericardium; Compression of vein; Systemic lupus erythematosus; Abdominal pain, unspecified site; Other chronic pain; Staphylococcus infection in conditions classified elsewhere and of unspecified site, other staphylococcus; Stridor; Angioneurotic edema, not elsewhere classified; Unspecified accident; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; ; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,155726.0,14864,2142-08-16,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",171,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,155726.0,14864,2142-08-16,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",146,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,155726.0,14864,2142-08-16,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",138,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,155726.0,14864,2142-08-16,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",116,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,155726.0,14864,2142-08-16,14861,174489.0,2142-07-04,Discharge summary,"Admission Date: [**2142-7-3**] Discharge Date: [**2142-7-4**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2817**] +Chief Complaint: +dyspnea, hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +discharged on [**7-1**] after presenting for hypertensive urgency and +dyspnea for which she received iv medication in the ED, but was +otherwised managed with oral antihypertensives and CPAP. +. +She was doing well until the evening of [**7-2**] when she notes the +gradual onset of dyspnea. She denied f/c/cp/ha/abd +pain/diarrhea, or constipation. She was having regular, soft, +daily BMs. +. +On [**7-3**] she awoke, and describes n/v x 2, with increasing +dyspnea, and headache. She did not want to wait until dialysis +at 4PM and therefore presented to [**Hospital1 18**]. +. +In ED VS= 97.7 [**Telephone/Fax (2) 43606**] 100%RA. Labs were notable for HCT +23, PLT 66, WBC 3.3, all roughly at baseline. CXR without acute +process, ECG unchanged from prior. No UA sent, though she does +make some urine. She was started on nitro gtt with modest +improvement of SBPs to 210s, then labetalol 20mg iv x1 followed +by labetalol gtt with BP 221/130 at the time of transfer. She +refused abdominal CT. Renal was consulted, but felt HD not +indicated today. +. +. +ROS: Negative for fevers, chills, chest pain, diarrhea, rash, +joint pains. +n/v as above. +abdominal pain unchanged from her +baseline. +dyspnea, +HA. denies visual changes, slurrring +speech, numbness, weeakness. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - 97.7 88 220/150 19 100%2L BC. +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM. +Neck: supple, no LAD, full ROM. +Lungs: CTA B, with few crackles at bases. +CV: RR, nl S1, S2 +S3, no rubs appreciated. +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation, negative [**Doctor Last Name **], no rebound, gaurding. +Ext: WWP, 1+ dp/pt pluses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +Lab Results on Admission: + +[**2142-7-3**] 11:37AM GLUCOSE-95 UREA N-40* CREAT-7.4*# SODIUM-140 +POTASSIUM-3.8 CHLORIDE-105 TOTAL CO2-23 ANION GAP-16 +ALT(SGPT)-14 AST(SGOT)-44* LD(LDH)-264* ALK PHOS-115 TOT +BILI-0.4 ALBUMIN-3.2* +WBC-3.6* RBC-2.61* HGB-7.6* HCT-23.4* MCV-90 MCH-29.0 MCHC-32.4 +RDW-18.3* +[**2142-7-3**] 11:37AM NEUTS-71.6* LYMPHS-23.0 MONOS-3.7 EOS-1.5 +BASOS-0.2 PLT COUNT-66* PT-14.0* PTT-34.5 INR(PT)-1.2* +[**2142-7-3**] 06:00PM CK-MB-5 cTropnT-0.17*CK(CPK)-58 + +[**2142-7-3**] CXR: +IMPRESSION: Unchanged moderate cardiomegaly with pulmonary +edema. Again +underlying pneumonia in the lung bases cannot be completely +excluded and +evaluation after appropriate diuresis could be performed if +pneumonia remains a clinical concern. + + +Brief Hospital Course: +24F with h/o SLE, ESRD on HD, malignant HTN, h/o SVC syndrome, +PRES, prior ICH, and recent SBO, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - On presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her PO +meds. Hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below SBP 120. She evenutally became hypotensive to SBP +of 90 which resolved on its own. She was continued on CPAP +overnight and discontinued in the am. She was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. She remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - On presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. She +did have hypoactive bowel sounds on admission. She was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with HD with plan to follow BMs +closley. Her pain improved the am of discharge and she had no +further vomiting. +. +# ESRD on HD - She is currently getting HD SaTuTh, though did +not get HD on the day of presenation. As there was no acute +indication for HD on presentation, she received HD on the +following am, day of discharge. She was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] CKD and SLE, currently +above baseline, though has h/o GIB. She received 2 unit PRBCs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of PPI [**Hospital1 **]. +. +# SLE - continue home regimen of prednisone 4mg po qdaily. +. +# h/o SVC thrombosis - pt with goal INR [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic INR. INR +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg PO 3X/WEEK +(TU,TH,SA). +. +# depression - continued on celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24H (every 24 hours). + +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) patch Transdermal +every seventy-two (72) hours. +6. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for hypertension. +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +11. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +12. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). Tablet(s) +14. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +15. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +VNA + +Discharge Diagnosis: +Primary: +hypertensive emergency +anemia, erythropoetin deficiency + +Secondary: +chronic renal failure on hemodialysis +lupus nephritis + + +Discharge Condition: +Hemodynamically stable. + + +Discharge Instructions: +You were admitted for hypertensive urgency and treated in the +intensvie care unit with IV medications to decrease your blood +pressure. You also received 2 units of blood and hemodialysis +before you were discharged home. + +It is essential that you take all of your prescribed blood +pressure medications and present regularly for your Tuesday, +Thursday, Saturday dialysis. + +Please return to the emergency department or call your primary +care physician if you develop any chest pain, shortness of +breath, fevers, or any other concerning symptoms. + +Followup Instructions: +You have the following appointment scheduled. Please contact +your provider if you are unable to make these appointments. + +Your dialysis is scheduled for Tuesday, Thursday, Saturday. + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",43,2142-07-03 14:48:00,2142-07-04 17:23:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24f with h/o sle, esrd on hd, malignant htn, h/o svc syndrome, +pres, prior ich, and recent sbo, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - on presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her po +meds. hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below sbp 120. she evenutally became hypotensive to sbp +of 90 which resolved on its own. she was continued on cpap +overnight and discontinued in the am. she was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. she remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - on presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. she +did have hypoactive bowel sounds on admission. she was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with hd with plan to follow bms +closley. her pain improved the am of discharge and she had no +further vomiting. +. +# esrd on hd - she is currently getting hd satuth, though did +not get hd on the day of presenation. as there was no acute +indication for hd on presentation, she received hd on the +following am, day of discharge. she was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] ckd and sle, currently +above baseline, though has h/o gib. she received 2 unit prbcs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of ppi [**hospital1 **]. +. +# sle - continue home regimen of prednisone 4mg po qdaily. +. +# h/o svc thrombosis - pt with goal inr [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic inr. inr +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg po 3x/week +(tu,th,sa). +. +# depression - continued on celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified iridocyclitis; Other primary cardiomyopathies; Abdominal pain, unspecified site; Other chronic pain; Nausea with vomiting; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other specified peripheral vascular diseases; Obstructive sleep apnea (adult)(pediatric); Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,155726.0,14864,2142-08-16,14860,136572.0,2142-06-20,Discharge summary,"Admission Date: [**2142-6-18**] Discharge Date: [**2142-6-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2145**] +Chief Complaint: +Acute Onset Dyspnea + +Major Surgical or Invasive Procedure: +Dialysis + + +History of Present Illness: +Please see MICU note for full details. In brief this is a 24 +y.o. woman with SLE, ESRD on HD, hx malignant HTN, h/o SVC +syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, frequently admitted +with hypertensive urgency/emergency who was admitted with acute +onset dyspnea after 2 weeks without dialysis given to unable to +get transportation ? despite Dr. [**Last Name (STitle) 7473**] attempting to arrange +transport for her (? refused to come). She was admitted +therefore on [**6-18**] to micu with VS: T 100.4 HR 108 BP 240/180 RR +28 POx100 RA. She was treated with nitro gtt, labetolol gtt and +dilaudid-these gtts were stopped at 0700. In the micu she was +dialyzed with 1.7L fluid removal (though + 300cc given +tranfusion). Her SOB is improved. Her hct was also noted to be +low (18->from 22 [**2142-6-5**]) so transfused 2 units PRBC's, recent +EGD with gastric ulcer [**5-29**], guaiac negative in ED, no BM in +unit, hemolysis w/u negative. BP in icu 140/106 currently but of +note was hypotensive on HD to 86/62. She notes sob improved +rapidly on arrival. + +ROS: Currently she has no complaints. She notes at home her +abdominal pain is at baseline for her, felt mid epigastric, for +which she takes dilaudid 4mg up to [**Hospital1 **]. She has been getting HD +via right femoral catheter which is not painful, no discharge +from the sight. She denies HA, visual changes, cough, chest pain +or pressure, orthostatic changes, palpitations, nausea, +vomiting, constipation, diarrhea, melena, brbpr, dysuria, +hematuria, rash, swelling, orthopnea, pnd. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - T: 97.7, BP: 140/99 P: 88 R: 19 O2: 98% on RA +General: Sleeping comfortably but awakens easily, alert, +oriented x3 +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM, moon facies +Neck: supple, JVP flat, no LAD, full ROM, left EJ in place +Lungs: coarse BS throughout, no W/R/R, no decreased BS at bases + +CV: S1, S2 nl, no m/r/g appreciated +Abdomen: Firm, non-tender to palpation, no masses or +organomegally +Ext: Warm, well perfused, 1+ DP/PT, no clubbing, cyanosis or +edema +Neuro: a&o x3, motor [**5-15**] UE/LE bilaterally + + +Pertinent Results: +[**2142-6-18**] 05:28PM HCT-26.0*# +[**2142-6-18**] 11:38AM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-NORMAL MICROCYT-OCCASIONAL POLYCHROM-NORMAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-6-18**] 05:04AM GLUCOSE-85 UREA N-72* CREAT-10.4* SODIUM-139 +POTASSIUM-5.5* CHLORIDE-109* TOTAL CO2-14* ANION GAP-22* +[**2142-6-18**] 05:04AM LD(LDH)-264* TOT BILI-0.2 +[**2142-6-18**] 05:04AM CALCIUM-6.6* PHOSPHATE-6.5* MAGNESIUM-1.6 +[**2142-6-18**] 05:04AM HAPTOGLOB-142 +[**2142-6-18**] 05:04AM WBC-3.4* RBC-1.93* HGB-5.8* HCT-17.0* MCV-88 +MCH-30.0 MCHC-34.2 RDW-18.4* +[**2142-6-18**] 05:04AM PLT COUNT-97* +[**2142-6-18**] 01:34AM GLUCOSE-84 UREA N-70* CREAT-10.5*# SODIUM-136 +POTASSIUM-5.6* CHLORIDE-108 TOTAL CO2-14* ANION GAP-20 +[**2142-6-18**] 01:34AM estGFR-Using this +[**2142-6-18**] 01:34AM ALT(SGPT)-10 AST(SGOT)-39 ALK PHOS-108 TOT +BILI-0.2 +[**2142-6-18**] 01:34AM LIPASE-115* +[**2142-6-18**] 01:34AM ALBUMIN-3.2* CALCIUM-6.6* PHOSPHATE-6.8* +MAGNESIUM-1.7 +[**2142-6-18**] 01:34AM WBC-4.5 RBC-2.08* HGB-6.0* HCT-18.3* MCV-88 +MCH-28.6 MCHC-32.5 RDW-18.6* +[**2142-6-18**] 01:34AM NEUTS-78.5* LYMPHS-16.5* MONOS-3.0 EOS-1.4 +BASOS-0.6 +[**2142-6-18**] 01:34AM PLT COUNT-104* +[**2142-6-18**] 01:34AM PT-15.0* PTT-33.6 INR(PT)-1.3* + +Brief Hospital Course: +# Dyspnea: Pt's dypsnea improved on admission to the ED prior to +HD. Based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. Upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# Anemia: Pt's baseline 1 month ago noted to be low 30s, since +then her Hct has trended down to 22 several week prior to +admission. As she missed dialysis she was not able to reserve +her Eopgen which likely complicated her anemia. Pt underwent +hemolysis workup in the ICU which was ultimately negative. She +was given several units of PRBC and bumped her Hct +appropriately. She was noted to be guaiac negative on +examination. + +# Hypertension: Pt was initially admitted with hypertension. +Following transition to the floor she was placed on her home +regimen. She was noted to be hypotensive in dialysis which is +likely due to her being on Labetalol, Nitro gtt on dialysis. Pt +was discharged on her home BP regimen with follow up with her +nephrologist. + +# Chronic Abdominal Pain: Pt had noted some intermittent +abdominal pain which has been chronic. Lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. Pt was able to tolerate a PO diet prior to her +discharge. Pt was continued on her outpatient regimen of +Dilaudid, Fentanyl patch, Neurontin. + +# GE junction Ulcer: Pt was continued on her PPI regimen [**Hospital1 **]. + +# SLE: Pt was continued on her home regimen of Prednisone 4mg +daily + +# History of DVT: Pt had a sub-therapeutic INR on admission. She +was discharged on Warfarin 3mg daily. + +# ESRD on HD: Pt was admitted for dyspnea in the setting of +missing 2 weeks of HD. The renal team followed Ms. [**Known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. Pt was continued on Sevelamer and +Epogen. + +# Seizure D/O: Pt was continued on her home regimen of keppra. + +# Depression: Pt was continued on her home regimen of Celexa. + + +Medications on Admission: +1. Nifedipine 90 mg Tablet Sustained Release PO QAM +2. Nifedipine 60 mg Tablet Sustained Release PO QHS +3. Lidocaine 5 % transdermal one daily +4. Aliskiren 150 mg PO BID +5. Citalopram 20 mg PO DAILY (Daily). +6. Fentanyl 25 mcg/hr Patch Q72H (every 72 hours). +7. Prednisone 4mg PO DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Transdermal QSAT +9. Clonidine 0.3 mg/24 hr Patch Weekly Transdermal QSAT +10. Sevelamer HCl 400 mg Four (4) Tablet PO TID W/MEALS +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +13. Hydralazine 100 mg PO Q8H +14. Hydromorphone 2 mg 1-2 Tablets PO Q6H as needed for pain. +15. Pantoprazole 40 mg PO Q12H +16. LeVETiracetam 1,000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24 H (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: Malignant HTN, ESRD on HD, Shortness of breath +Secondary: Lupus + + +Discharge Condition: +Stable, afebrile + + +Discharge Instructions: +You were admitted to the hospital after you noticed some +shortness of breath. Whilst in the hospital you were noted to +have a low blood level (anemia) and you some fluid in your +lungs. We think your blood level was low because you were not +receiving your Epo shots, we think the fluid is from not +receiving dialysis. Before you were discharged from the hospital +your breathing was better. + +We recommend that you continue going to dialysis. + +We made no changes to your medications. + +If you notice any fevers, chills, nausea, vomiting, shortness of +breath, lightheadedness please return to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 +Provider: [**First Name4 (NamePattern1) **] [**Name Initial (NameIs) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-27**] 2:00 + + + [**Name6 (MD) **] [**Name8 (MD) **] MD [**MD Number(2) 2158**] + +",57,2142-06-18 03:11:00,2142-06-20 16:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ANEMIA," +# dyspnea: pts dypsnea improved on admission to the ed prior to +hd. based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# anemia: pts baseline 1 month ago noted to be low 30s, since +then her hct has trended down to 22 several week prior to +admission. as she missed dialysis she was not able to reserve +her eopgen which likely complicated her anemia. pt underwent +hemolysis workup in the icu which was ultimately negative. she +was given several units of prbc and bumped her hct +appropriately. she was noted to be guaiac negative on +examination. + +# hypertension: pt was initially admitted with hypertension. +following transition to the floor she was placed on her home +regimen. she was noted to be hypotensive in dialysis which is +likely due to her being on labetalol, nitro gtt on dialysis. pt +was discharged on her home bp regimen with follow up with her +nephrologist. + +# chronic abdominal pain: pt had noted some intermittent +abdominal pain which has been chronic. lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. pt was able to tolerate a po diet prior to her +discharge. pt was continued on her outpatient regimen of +dilaudid, fentanyl patch, neurontin. + +# ge junction ulcer: pt was continued on her ppi regimen [**hospital1 **]. + +# sle: pt was continued on her home regimen of prednisone 4mg +daily + +# history of dvt: pt had a sub-therapeutic inr on admission. she +was discharged on warfarin 3mg daily. + +# esrd on hd: pt was admitted for dyspnea in the setting of +missing 2 weeks of hd. the renal team followed ms. [**known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. pt was continued on sevelamer and +epogen. + +# seizure d/o: pt was continued on her home regimen of keppra. + +# depression: pt was continued on her home regimen of celexa. + + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Anemia of other chronic disease; Hyperpotassemia; Systemic lupus erythematosus; Abdominal pain, other specified site; Other chronic pain; Hypotension, unspecified; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Depressive disorder, not elsewhere classified; Personal history of venous thrombosis and embolism; Noncompliance with renal dialysis]" +109,155726.0,14864,2142-08-16,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",72,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,155726.0,14864,2142-08-16,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",90,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,196721.0,14863,2142-07-23,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",156,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,196721.0,14863,2142-07-23,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",147,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,196721.0,14863,2142-07-23,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",122,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,196721.0,14863,2142-07-23,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",92,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,196721.0,14863,2142-07-23,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",114,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,174489.0,14861,2142-07-04,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",173,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,102024.0,14859,2142-06-05,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",18,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,102024.0,14859,2142-06-05,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",173,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,102024.0,14859,2142-06-05,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",164,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,102024.0,14859,2142-06-05,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",144,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,102024.0,14859,2142-06-05,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",136,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,102024.0,14859,2142-06-05,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",133,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,102024.0,14859,2142-06-05,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",108,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,102024.0,14859,2142-06-05,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",99,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,102024.0,14859,2142-06-05,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",74,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,102024.0,14859,2142-06-05,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",66,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,151240.0,14858,2142-05-18,14799,125288.0,2141-11-23,Discharge summary,"Admission Date: [**2141-11-18**] Discharge Date: [**2141-11-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Hypertensive Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +(from MICU admit note) +24yoF ESRD-HD, SLE, HTN presents with 1 month abdominal pain and +hypertension. Pt has had work-up over recent months for abd +pain, including exploratory laparotomy, all of which essentially +(-). +Was admitted [**Date range (1) 34629**], for abdominal pain, then returned [**11-16**] +for sob with (-)CTA, dc'ed [**11-17**]. +In [**Hospital1 18**] ED, T98.5 hr95 BP 220/110 then 183/133 RR13 O2 100% on +RA, rectal exam negative, guaiac(-), pelvic exam unremarkable +with no cervical motion tenderness. Renal was consulted, taken +for hemodialysis. CT abd showed large ascites, no other +pathology; CT head improved from prior with no acute ICH; +cxr(-). Given iv dilaudid for abdominal pain. BP treated with +10mg iv labetalol. Blood and urine cultures drawn, peritoneal +fluid cx sent from catheter. Admitted to MICU for hypertension +management. Access: R-HD catheter, 1 pIV in hand, 1 +non-functioning peritoneal dialysis catheter. + +Past Medical History: +PMH: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSH: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +PE: T:99.4 BP:158/108 HR:95 RR:12 O2 100% RA +GEN: NAD/ pt eyes closed due to pain/ pleasant despite pain +HEENT: AT, NC, PERRLA, EOMI on R eye, L eye prosthesis, no +conjuctival injection, anicteric, OP clear, MMM +Neck: supple, no LAD +CV: S1 & S2, RRR II/VI HSM at R/L USB, no rubs/gallops +PULM: CTAB, no w/r/r +ABD: soft, mildly tender at PD catheter, ND, + BS, midline +incision with steri-stripes, PD catheter dressing C/I/D +EXT: warm, dry, +2 distal pulses BL, no edema +NEURO: alert & oriented, CN II-XII grossly intact (except L +eye), 5/5 strength throughout. No sensory deficits to light +touch appreciated. No asterixis +PSYCH: appropriate affect + +Pertinent Results: +Admission Labs: +[**2141-11-18**] 07:00AM BLOOD WBC-3.7* RBC-3.35* Hgb-9.7* Hct-30.7* +MCV-92 MCH-28.9 MCHC-31.5 RDW-17.7* Plt Ct-142* +[**2141-11-18**] 07:00AM BLOOD PT-14.4* PTT-30.0 INR(PT)-1.3* +[**2141-11-18**] 07:00AM BLOOD Glucose-86 UreaN-22* Creat-5.0* Na-140 +K-4.3 Cl-105 HCO3-25 AnGap-14 +[**2141-11-18**] 07:00AM BLOOD ALT-8 AST-39 AlkPhos-92 TotBili-0.3 +[**2141-11-18**] 07:00AM BLOOD Lipase-76* +[**2141-11-18**] 07:00AM BLOOD Calcium-7.6* Phos-4.7* Mg-1.9 +[**2141-11-18**] 11:00PM ASCITES WBC-1265* RBC-1680* Polys-43* Lymphs-1* +Monos-2* Mesothe-11* Macroph-43* +[**2141-11-18**] 10:05AM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.010 +[**2141-11-18**] 10:05AM URINE Blood-NEG Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2141-11-18**] 10:05AM URINE RBC-0 WBC-0 Bacteri-OCC Yeast-NONE +Epi-[**3-15**] + +Discharge Labs: +[**2141-11-23**] 04:40AM BLOOD WBC-2.9* RBC-3.08* Hgb-9.0* Hct-28.3* +MCV-92 MCH-29.2 MCHC-31.8 RDW-17.5* Plt Ct-182 +[**2141-11-23**] 04:40AM BLOOD PT-20.8* PTT-76.1* INR(PT)-2.0* +[**2141-11-23**] 04:40AM BLOOD Glucose-80 UreaN-21* Creat-4.7* Na-139 +K-4.8 Cl-106 HCO3-24 AnGap-14 +[**2141-11-23**] 04:40AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.8 +[**2141-11-22**] 04:55AM BLOOD TSH-6.1* +[**2141-11-23**] 04:40AM BLOOD Free T4-1.2 + +Blood cx ([**11-18**], [**11-19**]): 1/4 bottles with coag neg Staph, [**3-14**] NGTD +Urine cx ([**11-18**]): mixed flora c/w contamination +Peritoneal fluid ([**11-18**]): Gram stain 2+ polys. Culture no growth. + +Imaging: +CXR Portable ([**11-18**]): Since [**2141-11-16**], heart size +enlargement is unchanged due to known pericardial effusion. +Lungs are otherwise clear. Hilar contours are normal. +Incidentally, widening of both acromioclavicular joints is +unchanged. + +CT A/P ([**11-18**]): +1. No evidence of bowel obstruction or rim-enhancing fluid +collection. +2. Large ascites, slightly increased from [**2141-11-13**], with +peritoneal dialysis catheter in place. Interval removal of +surgical skin staples along the abdomen. +3. Moderate pericardial effusion as before. +4. Symmetric heterogeneous attenuation of the kidneys could be +related to +renal failure; however, pyelonephritis could also give this +appearance. +Appearance of the kidneys is unchanged from [**2141-11-13**]. + +CT Head w/o contrast ([**11-18**]): +1. No evidence of acute intracranial hemorrhage. +2. Regions of hypoattenuation in the bifrontal white matter and +left +posterior temporal lobe have resolved since [**2141-6-11**]. No new +regions of +hypoattenuation seen. + +Brief Hospital Course: +1) Hypertension: Patient has history of extremely labile +hypertension on an aggressive outpatient regimen. Overnight in +the MICU, patient required IV and PO labetalol for SBP > 200. +Her hydralazine was increased from 75mg to 100mg TID with mild +improvement. Her labetalol was also increased from 300mg to +400mg TID. Her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. TSH +was sent and elevated, although free T4 was normal. Plasma +metanephrines were sent and pending at discharge. + +2) Abdominal pain: CT scan showed increasing ascites, but no +acute pathology. Peritoneal fluid was obtained and contained 544 +polys. Treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing GPC pairs/clusters. Blood cultures ended up growing 1 +out of 4 bottles coag-neg Staph, likely contaminant, so +vancomycin was stopped. Since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. The peritoneal +cultures remained negative. Her PD catheter was left in place as +the patient refuses HD any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) SVC/brachiocephalic thrombosis: Patient's INR was +subtherapeutic on admission at 1.3. Due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +This was continued during her admission and her warfarin was +increased to 5mg daily. Her INR reached 2.0 at discharge +(therapeutic range 2-3). The dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) Anxiety: Patient noted feeling short of breath and anxious +around the time of her recent admissions. Her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. They felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +TSH and metanephrines as above, and starting citalopram 20mg, +which was done. She was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h PRN. Patient +is agreeable to outpatient follow up with [**Company 191**] social work, and +potential CBT. These can be arranged by her PCP. + +Medications on Admission: +1. Aliskiren 150 mg [**Hospital1 **] +2. Clonidine 0.3 mg/24 qwk +3. Prochlorperazine Maleate 10 mg prn +4. Hydromorphone 2 mg Tablet Sig: [**1-11**] q6 prn +5. Bisacodyl 10mg [**Hospital1 **] +6. Ergocalciferol (Vitamin D2) 50,000 qmonth +7. Hydralazine 75mg tid +8. Hydralazine scale prn +9. Labetalol 300 mg tid +10. Nifedipine 90 mg qd +11. Prednisone 4mg qd +12. Warfarin 2 mg qd at 4pm + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +4. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Hospital1 766**]). +5. Labetalol 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +6. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +7. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Hospital1 **]:*180 Tablet(s)* Refills:*2* +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for 7 days. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +11. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q8H (every 8 +hours) as needed for anxiety. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +12. Celexa 20 mg Tablet Sig: One (1) Tablet PO once a day. +[**Hospital1 **]:*30 Tablet(s)* Refills:*2* +13. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed. +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +15. Hydralazine 25 mg Tablet Sig: One (1) Tablet PO q30 min prn +as needed for hypertension: for SBP > 180. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Hypertensive urgency +Headache +Abdominal pain +Anxiety + +Secondary Diagnosis: +HTN +SLE +ESRD on HD +SVC and IJ thrombosis, chronic +Anemia + + +Discharge Condition: +Stable, BPs improved. + + +Discharge Instructions: +You were admitted with elevated blood pressures, headache, and +abdominal pain. You were found to have increased amounts of +white blood cells in your abdominal cavity, but this was not +infected. Your abdominal pain resolved and you continued to have +intermittent headaches. Your blood pressure medications were +adjusted as below. You were also seen by psychiatry who +recommended starting new medications for your anxiety. + +The following changes were made to your medication regimen: +- We increased your hydralazine to 100 mg three times a day. +- We also increased your labetalol to 400 mg three times a day. +- We have started a medication called celexa 20 mg daily as well +as ativan 1 mg three times a day as needed for anxiety. +- We have increased your coumadin to 4 mg daily. +- Please continue taking all other medications as previously +prescribed. + +Call your doctor or return to the emergency room if you +experience any of the following: worsening abdominal pain, +nausea, vomiting, blurry vision, worsening headache, fever > +101. + +Followup Instructions: +Please follow-up with your PCP [**Name Initial (PRE) 176**] 1 week. + +Please continue to follow with your nephrologist and go to +outpatient dialysis as previously arranged. + +Please discuss with your PCP the possibility of talking to a +social worker at [**Name (NI) 191**]. + +You will need to continue to have your INR monitored at [**Hospital 191**] +[**Hospital 2786**] clinic. Please have this level checked on +[**Hospital 766**], [**11-27**]. + + + +Completed by:[**2141-11-23**]",176,2141-11-18 14:00:00,2141-11-23 16:42:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +1) hypertension: patient has history of extremely labile +hypertension on an aggressive outpatient regimen. overnight in +the micu, patient required iv and po labetalol for sbp > 200. +her hydralazine was increased from 75mg to 100mg tid with mild +improvement. her labetalol was also increased from 300mg to +400mg tid. her blood pressure also seemed to improve when her +pain decreased and was normal in the middle of the night. tsh +was sent and elevated, although free t4 was normal. plasma +metanephrines were sent and pending at discharge. + +2) abdominal pain: ct scan showed increasing ascites, but no +acute pathology. peritoneal fluid was obtained and contained 544 +polys. treatment was started with metronidazole and +levofloxacin, as well as vancomycin as 1 blood culture was +growing gpc pairs/clusters. blood cultures ended up growing 1 +out of 4 bottles coag-neg staph, likely contaminant, so +vancomycin was stopped. since nephrology felt her peritoneal +fluid polys were inflammatory but not infectious, the +levofloxacin and metronidazole were stopped. the peritoneal +cultures remained negative. her pd catheter was left in place as +the patient refuses hd any longer than necessitated by the +healing of her recent laparotomy (see prior d/c summaries). + +3) svc/brachiocephalic thrombosis: patients inr was +subtherapeutic on admission at 1.3. due to the proximal location +of her old venous thrombi, she was started on a heparin gtt. +this was continued during her admission and her warfarin was +increased to 5mg daily. her inr reached 2.0 at discharge +(therapeutic range 2-3). the dose was lowered to 4mg daily at +discharge to prevent overshooting the therapeutic range, but the +patient will have close follow up with coumadin clinic, with +dose titrations as needed. + +4) anxiety: patient noted feeling short of breath and anxious +around the time of her recent admissions. her nephrologist felt +this may be contributing to her recurrent pain and hypertension, +so psychiatry was consulted. they felt her symptoms were +suggestive of anxiety and panic attacks, recommended checking +tsh and metanephrines as above, and starting citalopram 20mg, +which was done. she was advised on breathing exercises, which +seemed to have benefit, and given lorazepam 1mg q8h prn. patient +is agreeable to outpatient follow up with [**company 191**] social work, and +potential cbt. these can be arranged by her pcp. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Anemia, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,102024.0,14859,2142-06-05,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",44,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,151240.0,14858,2142-05-18,14800,161950.0,2141-12-01,Discharge summary,"Admission Date: [**2141-11-24**] Discharge Date: [**2141-12-1**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Headache, abdominal pain + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24yo F w/PMHx of ESRD on HD, SLE, malignant HTN presents with +headache and abdominal pain beginning this morning, awakening +her from sleep. Had been previously discharged from [**Hospital1 **] +yesterday after being admitted for hypertension and abdominal +pain. Has had extensive work-up for abdominal pain including +ex-lap on [**2141-10-27**] which was negative. Upon discharge yesterday +she states her abdominal pain had subsided. She had HD +yesterday without complications. She awoke at 6am with a +headache and crampy, stabbing abdominal pain. Took 2mg PO +Dilaudid without relief and came to ED. No nausea/vomiting, no +changes in vision, no fevers, chills, night sweats. No chest +pain, SOB, diarrhea. + +In the ED, initial vitals were T98.7, BP260/130, HR70, RR16. +Was initially given 10mg IV Labetalol X 2, 4mg Zofran for +nausea. No improvement in BP and started on Labetolol gtt. Got +1mg IV Dilaudid for pain. + +Currently, patient continues to complain of headache and +abdominal pain, both [**7-17**]. No vision changes, chest pain or +shortness of breath. Has been feeling increased anxiety +recently and saw psychiatrist, was put on Celexa. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + +Physical Exam: +T98.2, BP176/135, HR94, RR 22, 100% RA +Gen: well-appearing african-american woman, lying comfortably +HEENT: anicteric, L eye prosthetic non-reactive, R pupil +reactive, MMM, neck supple with submanibular LAD +CV: RRR, II/VI SEM best heard at apex +Pulm: CTA b/l +Abd: hyperactive bowel sounds, midline scar well-healed, soft, +diffusely tender to palpation, +rebound, no guarding. PD +catheter in LLQ without erythema or purulent material draining. ++dullness on percusion with evidence of clinical ascites. +Ext: no edema, no clubbing, 2+ peripheral pulses DP and radial. +R femoral HD [**Last Name (un) **] in place without erythema, purulance +Neuro: A&O X 3, CN intact II-XII, [**5-15**] motor strength in upper +and lower extremities + + +Pertinent Results: +Admission labs: + +CBC: +[**2141-11-26**] 05:21AM BLOOD WBC-3.5* RBC-3.07* Hgb-9.3* Hct-27.5* +MCV-90 MCH-30.1 MCHC-33.6 RDW-17.6* Plt Ct-180 +CHEM 10: +[**2141-11-26**] 01:16PM BLOOD Glucose-87 UreaN-17 Creat-4.0* Na-136 +K-5.2* Cl-106 HCO3-23 AnGap-12 +[**2141-11-26**] 09:20PM BLOOD Calcium-7.6* Phos-3.8 Mg-1.8 +COAGS: +[**2141-11-26**] 01:16PM BLOOD PT-23.9* PTT-40.2* INR(PT)-2.3* + +STUDIES: +1)Peritoneal fluid ([**11-26**]): negative for malignant cells. +Reactive mesothelial cells, macrophages, eosinophils and +lymphocytes. +2)BILAT UP EXT VEINS US ([**11-26**]): No evidence of deep vein +thrombosis of the right or left upper extremity. +3) MRI/MRA ([**11-30**]): FINDINGS: Examination is somewhat limited by +patient motion. T2/FLAIR sequences are unremarkable with +interval resolve of previously noted posterior abnormalities. +The major vessels appear patent proximally. There are stable +areas of low signal in the left frontal and right +occipetal/temporal lobes. +IMPRESSION: +1. Interval resolution of previously noted posterior white +matter +abnormalities. +2. Stable prior areas of hemorrhage within the left frontal and +right +occipital/temporal regions. +3. Very limited MRA as above. + + +Brief Hospital Course: +24yo F with SLE, ESRD on HD and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**Hospital Unit Name 153**] course: +The patient was admitted for blood pressure management and +evaluation of abd pain. An A-line was placed. EKG showed no +change from prior, and Abd x-ray showed a suggestion of RLL/R +diaphragm haziness. IV labetalol was started, and SBPS dropped +from 200s to 130s-160s. The patient had no symptoms of end-organ +damage. The renal team was consulted, and recommended no change +to home med regimen. The patient was found to be hypocalcemic, +and was started on calcium replacement therapy. When stable, +patient succesfully switched to PO meds and transferred to the +floor. + +Upon transfer to the floor, the following was her course: + +1. Hypertensive Urgency: Pt had had hemodialysis one day prior +to admission, so unlikely that she was volume overloaded. +Unclear what precipitated this episode of hypertensive urgency, +although suspect secondary to abdominal pain leading to an +anxiety which then precipitates hypertension. She may not have +been taking her medications secondary to pain. Negative serum +tox. On the floor, we continued hemodialysis Tu, Th, Sat. She +was initially continued on PO Labetolol 400mg TID, Hydralazine +100mg PO q8H, Nifedipine 90mg PO qday and clonidine; she +received hydralazine 10mg IV for goal BP < 180/100. Renal team +followed patient during this hospitalization. Per renal team +recs, labetalol was increased to 800mg TID due to poor blood +pressure control. Pt discharged on clonidine 0.3mg patch, +Hydralazine 100mg three times a day, Aliskiren 150mg twice a +day, Nifedipine 90mg daily and lobatalol 800mg TID. This +regimen worked well. + +2. Abdominal Pain: Extensive prior workup unrevealing. Pt had +recent CT scan during prior admission which did not show source +of abdominal pain. On admission, LFTs were normal except for +slightly low albumin, lipase was slightly elevated and KUB was +negative for free air or evidence of SBO. Peritoneal fluid was +negative for malignant cells but showed reactive mesothelial +cells, macrophages, eosinophils and lymphocytes. Negative gram +stain or peritoneal fluid cultures, excluding SBP as a cause of +the abdominal pain. PD catheter was not removed. Pt was +continued on PO dilaudid 1-2mg Q6h and pain resolved. She denied +N/V/diarrhea or constipation. + +3. ESRD: Pt on hemodialysis, on T/Th/Sat schedule. Renal +following patient closely throughout this hospitalization. Lytes +were checked frequently and kayexalate given prn. + +4. Hx of SVC/brachiocephalic DVT: Pt was initially +subtherapeutic on coumadin. Unclear if she had not been taking +Coumadin although patient reported that she has been taking all +home meds. We started heparin gtt to bridge to Coumadin. Once +therapeutic, continued Coumadin 5mg PO qday. + +5. Anxiety: Likely contributing to medical problems and could +have very well been the etiology of this admission. Although pt +stated she was taking her current medications, she did report +increased anxiety which can lead to medication non-compliance +and hypertension. Pt recently saw psychiatrist who started her +on Celexa. She was continued on celexa 20mg PO qday, ativan 1mg +PO q8hours PRN and psychiatry was re-consulted. Per psych recs, +started standing clonazepam. Pt refused psych VNA. Outpatient +PCP followup recommended. + +6. Headache NOS: Pt complained of R-sided HA for several weeks, +radiating to R jaw where patient had previous tooth extraction. +Right upper extremity ultrasound was negative for DVT. She +did not have any focal neuro findings, no visual deficits. She +was initially treated with tylenol PRN Q6h; pt requested IV +dilaudid for HA, but use of this medication by IV route was +limited by team. It was felt by the pain service that her HA did +not fit migraine, tension type HA or rebound HA. They +recommended increasing dilaudid to 4-6mg Q6h PRN, continuing +tylenol and starting neurontin 300mg Qhs which was slowly +titrated to 300mg [**Hospital1 **] for better control. Per pain recs, a +neurology consult was also obtained during this admission. +MRI/MRA showed interval resolution of previously noted posterior +white matter abnormalities and stable prior areas of hemorrhage +within the left frontal and right occipital/temporal regions, +but very limited MRA as above. Per pain recs, dilaudid was +further increased to 4mg q4h for better control of her HA. +Neurology recommended outpt f/u and Pt scheduled with [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**]. + +7. Anemia: Likely related to ESRD. No evidence of acute +bleeding. Hct remained stable during this hospitalization. + +8. SLE: no acute issues. continued Prednisone 4mg PO qday + +9. FEN: tolerated regular diet, repleted lytes PRN + +9. Prophylaxis: Heparin gtt, then coumadin, bowel regigmen + + + +Medications on Admission: +(from prior discharge summary) +Bisacodyl 10mg PO qday PRN +Prednisone 4mg PO qday +Aliskiren 150mg PO BID +Clonidine 0.3mg / 24 hr patch weekly qmonday +Labetalol 400mg PO TID +Warfarin 4mg PO qday +Nifedipine 90mg PO qday +Hydralazine 100mg PO q8H +Hydromorphone 2-4mg PO q4H PRN +Lorazepam 1mg PO q8H +Celexa 20mg PO qday +Prochlorperazine 10mg PO q6H +Colace 100mg PO BID +Hydralazine 25mg PO q30min PRN for HTN + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every [**Year (4 digits) 766**]). +3. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QMONTH (). +4. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +5. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO QHS (once a day +(at bedtime)). +[**Year (4 digits) **]:*100 Tablet(s)* Refills:*2* +8. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +[**Year (4 digits) **]:*90 Capsule(s)* Refills:*2* +9. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for headache. +[**Year (4 digits) **]:*84 Tablet(s)* Refills:*0* +10. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +[**Year (4 digits) **]:*60 Capsule(s)* Refills:*2* +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +[**Year (4 digits) **]:*60 Tablet(s)* Refills:*0* +14. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours). +15. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO every eight +(8) hours. +[**Year (4 digits) **]:*360 Tablet(s)* Refills:*2* +16. Bisacodyl 5 mg Tablet Sig: One (1) Tablet PO once a day as +needed for constipation. +[**Year (4 digits) **]:*30 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +1. Hypertensive Emergency +2. SLE +3. Headache, NOS +4. Abdominal pain + + +Discharge Condition: +BP better controlled. Headache managed on oral meds + + +Discharge Instructions: +You were admitted with abdominal pain, high blood pressure, and +headache. Your abdominal pain resolved - no serious cause of +this pain was found. Your blood pressure medications were +continued, and with an increased in one medication, the +labetalol. Your blood pressure improved. You should continue +the clonidine 0.3mg patch changed on [**Year (4 digits) 766**], Hydralazine 100mg +three times a day, Aliskiren 150mg twice a day, and Nifedipine +90mg daily. The dose of Labetalol was increased to 800 mg three +times daily by you kidney doctor and you are given a new +prescription. Please take all medications as listed below. + +For your headache, you had an MRI and MRA of the head, which did +not show a new or serious abnormality. You were seen by the +neurology and pain services. You should follow up at [**Hospital 878**] +clinic with Dr. [**First Name (STitle) **] [**Name (STitle) **] on [**2141-12-12**] at 6:30 PM (in +the evening). Your pain was managed by oral dilaudid, 4mg. You +should take this medication every 4 hours as needed. You were +also started on Gabapentin (also called Neurontin) for the +headache. The dose was slowly increased to twice a day. You +may not need as much dilaudid for your headache and should wean +this medication as tolerated, given it's potential for side +effects (constipation, lethargy, dependence). Finally, you will +likely need medications for constipation while you take +dilaudid. Take colace (a stool softener), senna (a laxative), +and bisacodyl (another laxative), as needed. + +It is really important that you have a primary care doctor. You +are scheduled with Dr. [**Last Name (STitle) **] (see below) next Tuesday. You +will need your INR checked since you are on coumadin. + +Call your doctor if you have worsened headache, chest pain, +confusion, or any other concerning symptom. + +Followup Instructions: +Please make sure you attend the following doctor appointments: +1) Dr. [**Last Name (STitle) 4883**] (nephrologist) on Tuesday, [**2141-12-5**] at 10AM. +Phone number [**Telephone/Fax (1) 60**]. +2) Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], at [**Location (un) **], [**Hospital Ward Name 23**] center, [**Location (un) **]. Phone:[**Telephone/Fax (1) 250**]. Date/Time:[**2141-12-5**] 3:20 +3) Neurology: Dr. [**Last Name (STitle) 43502**] [**Name (STitle) **]. He is located on the [**Location (un) **] of the [**Hospital Ward Name 23**] building. Phone:[**Telephone/Fax (1) 2574**] +Date/Time:[**2141-12-12**] 6:30 PM + + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2141-12-2**]",168,2141-11-24 16:11:00,2141-12-01 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +24yo f with sle, esrd on hd and malignant hypertension who +presented with abdominal pain and headache and was admitted for +hypertensive urgency. + +[**hospital unit name 153**] +the patient was admitted for blood pressure management and +evaluation of abd pain. an a-line was placed. ekg showed no +change from prior, and abd x-ray showed a suggestion of rll/r +diaphragm haziness. iv labetalol was started, and sbps dropped +from 200s to 130s-160s. the patient had no symptoms of end-organ +damage. the renal team was consulted, and recommended no change +to home med regimen. the patient was found to be hypocalcemic, +and was started on calcium replacement therapy. when stable, +patient succesfully switched to po meds and transferred to the +floor. + +upon transfer to the floor, the following was her ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other ascites; ; Systemic lupus erythematosus; Headache; Anemia in chronic kidney disease; Anxiety state, unspecified; Other chest pain; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Renal dialysis status; Acquired absence of organ, eye]" +109,151240.0,14858,2142-05-18,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",146,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,151240.0,14858,2142-05-18,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",126,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,151240.0,14858,2142-05-18,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",118,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,151240.0,14858,2142-05-18,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",115,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,151240.0,14858,2142-05-18,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",90,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,151240.0,14858,2142-05-18,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",81,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,151240.0,14858,2142-05-18,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",56,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,151240.0,14858,2142-05-18,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",48,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,151240.0,14858,2142-05-18,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",26,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,151240.0,14858,2142-05-18,14801,173633.0,2141-12-14,Discharge summary,"Admission Date: [**2141-12-8**] Discharge Date: [**2141-12-14**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 8104**] +Chief Complaint: +abdominal pain & hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis +PICC Line [**12-11**] + +History of Present Illness: +Ms [**Known lastname **] is a 24 year old woman with a history of CKD V (on HD) +from lupus nephritis, chronic intermittent abdominal pain, and +multiple prior ICU admissions for hypertensive urgency who +presented to the ED complaining of two days' of abdominal pain, +nausea, and loose stools. She was feeling well until after her +hemodialysis session on Wednesday. Thereafter, she complained of +nausea with occasional vomitting and has been unable to keep +down any of her oral medications. She also has had diffuse +abdominal pain consistent with her prior flares of pain as well +as her typical diffuse headache. The headache in particular was +worsening and, for her, this is a sign of poorly-controlled +hypertension so she came to the [**Hospital1 18**] ED. Upon arrival to the +ED, she was afebrile, BP 240/184, HR 109, RR 16, Sat 99% on room +air. She was given 4 mg of IV ondansetron, [**1-11**] inch intropaste, +1 mg of IV hydromorphone x3, 1000cc of NS, and was put on a +labetalol drip which had to be increased up to 2 mg/min. A head +CT showed no acute abnormality (including hemorrhage) and an +abdominal CT showed some possible mild colitis, though it is +unclear if this is due to her recent peritoneal dialysis. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 97.9 BP 165/120 HR 93 RR 12 Sat 100% ra +Gen: mildly fatigued, but no distress +HEENT: oropharynx clear +Neck: no JVP, no LAD +Chest: clear to auscultation throughout, no w/r/r +CV: reg rate/rhythm, nl s1s2, ? s4, no murmurs or rubs heard +Abdomen: soft, tender diffusely to moderate palpation without +rebound or guarding; hyperactive bowel sounds; no masses or HSM, +PD catheter in palce +Extr: no edema, 2+ PT pulses +Neuro: alert, appropriate, strength grossly intact in all four +limbs +Skin: no rashes + + +Pertinent Results: +[**2141-12-14**] 05:53AM BLOOD WBC-4.3 RBC-2.81* Hgb-8.6* Hct-25.6* +MCV-91 MCH-30.7 MCHC-33.8 RDW-19.3* Plt Ct-148* +[**2141-12-14**] 05:53AM BLOOD PT-42.6* PTT-51.0* INR(PT)-4.7* +[**2141-12-10**] 05:10AM BLOOD Ret Aut-2.5 +[**2141-12-14**] 05:53AM BLOOD Glucose-83 UreaN-21* Creat-5.1*# Na-138 +K-5.3* Cl-105 HCO3-24 AnGap-14 +[**2141-12-10**] 05:10AM BLOOD LD(LDH)-234 Amylase-347* TotBili-0.1 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-10**] 05:10AM BLOOD Lipase-72* +[**2141-12-14**] 05:53AM BLOOD Calcium-8.2* Phos-4.5 Mg-1.7 +[**2141-12-10**] 05:10AM BLOOD Hapto-142 +[**2141-12-8**] 04:02AM BLOOD calTIBC-138* VitB12-445 Folate-18.5 +Ferritn-220* TRF-106* + +ON ADMISSION: +[**2141-12-7**] 09:50PM BLOOD WBC-4.5 RBC-2.78* Hgb-8.4* Hct-25.2* +MCV-91 MCH-30.2 MCHC-33.3 RDW-19.2* Plt Ct-158 +[**2141-12-7**] 09:50PM BLOOD Neuts-65.2 Lymphs-23.4 Monos-8.0 Eos-2.9 +Baso-0.4 +[**2141-12-7**] 09:50PM BLOOD PT-14.7* PTT-33.4 INR(PT)-1.3* +[**2141-12-8**] 04:02AM BLOOD Ret Aut-2.5 +[**2141-12-7**] 09:50PM BLOOD Glucose-89 UreaN-25* Creat-5.1*# Na-139 +K-4.8 Cl-104 HCO3-26 AnGap-14 +[**2141-12-7**] 09:50PM BLOOD ALT-14 AST-51* AlkPhos-94 TotBili-0.3 +[**2141-12-7**] 09:50PM BLOOD Lipase-89* +[**2141-12-7**] 09:50PM BLOOD Albumin-3.3* Calcium-8.3* Phos-4.9* +Mg-1.9 +[**2141-12-7**] 09:54PM BLOOD Glucose-75 Lactate-1.3 Na-139 K-4.8 +Cl-101 calHCO3-23 + +Micro: + +Blood Cx: [**12-7**], [**12-7**], [**12-11**], [**12-11**] No growth + +FECAL CULTURE (Final [**2141-12-10**]): NO SALMONELLA OR SHIGELLA +FOUND. + + CAMPYLOBACTER CULTURE (Final [**2141-12-10**]): NO CAMPYLOBACTER +FOUND. + + OVA + PARASITES (Final [**2141-12-8**]): + NO OVA AND PARASITES SEEN. + This test does not reliably detect Cryptosporidium, +Cyclospora or + Microsporidium. While most cases of Giardia are detected +by routine + O+P, the Giardia antigen test may enhance detection when +organisms + are rare. + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2141-12-8**]): + Feces negative for C.difficile toxin A & B by EIA. + (Reference Range-Negative). + +CT HEAD [**2141-12-8**]: +IMPRESSION: +1. No acute intracranial pathology including no hemorrhage. +2. The hypodensities noted in the parietal white matter are +stable. However +in the setting of the hypertension, PRES cannot be excluded. If +further +evaluation is required MR can be obtained. + +CT Abdomin/Pelvis [**2141-12-8**] +IMPRESSION: +1. Moderate amount of free fluid in the pelvis is compatible +with the +patient's known peritoneal dialysis. Unchanged peritoneal +enhancement. + +2. Stable liver hemangioma. + +CXR [**12-11**] +IMPRESSION: Small left pleural effusion. Left lower lobe opacity +which is +either atelectasis versus pneumonia. + + +Brief Hospital Course: +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +MICU course: +Current plan on transfer +24 year old woman with CKD V and severe hypertension due to SLE +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. Hypertensive urgency: +The patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. Initially her blood pressure over-corrected to +SBPs in the 80s (patient was asymptomatic). Her clonidine patch +and hydralazine was held and she again became hypertensive with +SBPs 190s. The patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. The following dialysis the +patient asymptomatic with SBPs in 80s, MAPs 60s asymptomatic +again. Her hydralazine was stopped and continued on all her +other home medications at the advice of renal. The patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + On [**12-11**] the patient's SBP dropped to the 80's and due to her +pain medications she was extremely lethargic, but arousable. A +PICC line was placed because lack of access and she was bolused +250cc NS. The patient's pressures responded and additional +narcotics were held due to her mental status. The patient's +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. The patient did require IV hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. A possible component to the patient's +malignant hypertension is likely due to OSA. An inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on BiPAP for OSA. The patient was continuned on her +admission hypertensive regimen. +. +2. Abdominal pain: The etiology of her abdominal pain is +unclear, but has been a chronic issue for her. A CT scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +The patient also had diarrhea, but stool studies were negative. +The patient's pain was initially treated with hydromorphone, but +because of the patient's lethargy on [**12-11**] they were initially +held. She continued to complain of severe abdominal pain. She +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. Surgery was +consulted in regards to removal of her PD catheter, but given +that she may return to PD it was deferred to the outpatient +setting. + +3. CKD V from lupus nephritis: The patient was continued on HD +during her admission. She was also continued on her home +prednisone dose. She was closely followed by the renal team. +. +4. History of SVC/subclavian vein thrombus: The patient was +found to have a subtherapeutic INR on admission 1.3. She was +started on a heparin gtt and continued on coumadin. The +patient's heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her PICC line was +placed. She was therapetuic the same day and her heparin gtt +was stopped. On discharge her coumadin was supratherapeutic +(4.7) and was held. She will have her INR checked at HD. +. +5. Anemia: The patient's Hct slowly trended down. She was +guaiac negative and hemolysis labs were negative. She was +transfused 1U pRBC at HD on [**12-12**]. She was also given epo at HD. + + + +Medications on Admission: +prednisone 4 mg daily +clonidine 0.3 mg/day patch qWeek +ergocalciferol 50,000 units qMonth +nifedipine SR 90 mg daily +hydralazine 100 mg q8h +citalopram 20 mg daily +warfarin 2 mg qhs +gabapentin 300 mg [**Hospital1 **] +hydromorphone 4 mg q4h prn +clonazepam 0.5 mg [**Hospital1 **] +alikiren 150 mg [**Hospital1 **] +docusate 100 mg [**Hospital1 **] +senna 8.6 mg [**Hospital1 **] prn +acetaminophen prn +labetalol 800 mg q8h +bisacodyl 5 mg daily prn + + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Hydromorphone 4 mg Tablet Sig: One (1) Tablet PO every four +(4) hours as needed for pain. +[**Hospital1 **]:*84 Tablet(s)* Refills:*0* +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain, fever. +10. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). +13. Ativan 0.5 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed: please take as needed for anxiety prior to CPAP at +bedtime. +[**Hospital1 **]:*30 Tablet(s)* Refills:*0* +14. CPAP +Home CPAP +Dx: OSA +Prefer: AutoCPAP/ Pressure setting [**5-20**] +Alt: Straight CPAP/ Pressure setting 7 + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Hypertensive Urgency +Abdominal Pain +ESRD on HD +SVC Thrombus + +Secondary: +Systemic lupus erythematosus +Malignant hypertension +Thrombocytopenia +HOCM +Anemia +History of left eye enucleation +History of vaginal bleeding +Thrombotic microangiopathy + + +Discharge Condition: +Stable + + +Discharge Instructions: +It was a pleasure taking care of you while you were in the +hospital. You were admitted to [**Hospital1 18**] because of elevated blood +pressure and abdominal pain. You were initially admitted to the +ICU and your blood pressure was controlled. You were stabilized +and transferred back to th floor. Your pressures remained +stable throughout the rest of your stay. Additionally, you had +abdominal pain and diarrhea. Your stool was tested for +infections and was negative. Your diarrhea resolved without +intervention. Your abdominal pain was controlled with pain +medications. You had a sleep study in the hospital which showed +that you had sleep apnea. + +Please continue to take your medications as prescribed. +1. Please do not take your coumadin until your doctor tells you +to. + +Please follow up with the appointments below. + +Please call your PCP or go to the ED if you experience chest +pain, palpitations, shortness of breath, nausea, vomiting, +fevers, chills, or other concerning symptoms. + +Followup Instructions: +You will have dialysis at [**Location (un) **] Dialysis on your normal +schedule. You need to go to dialysis on Saturday. + +Please follow-up with the Sleep Clinic in [**12-19**] @ 11:45 +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +[**Telephone/Fax (1) 612**] + +Please follow-up with your PCP [**Last Name (NamePattern4) **] [**1-11**] weeks +PCP: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] + + + +Completed by:[**2141-12-16**]",155,2141-12-08 01:40:00,2141-12-14 17:16:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +micu course: +current plan on transfer +24 year old woman with ckd v and severe hypertension due to sle +admitted with flare of chronic abdominal pain and hypertensive +urgency. + +1. hypertensive urgency: +the patient was initially maintained on a labetalol drip and +hydralazine iv prn until oral anti-hypertensives lowered her +blood pressure. initially her blood pressure over-corrected to +sbps in the 80s (patient was asymptomatic). her clonidine patch +and hydralazine was held and she again became hypertensive with +sbps 190s. the patient was restarted on a low dose clonidine +0.1 mg/24 hr patch, and hydralazine. the following dialysis the +patient asymptomatic with sbps in 80s, maps 60s asymptomatic +again. her hydralazine was stopped and continued on all her +other home medications at the advice of renal. the patient was +transferred to the floor on [**12-10**] after resolution of her +hypertensive urgency with a decreased blood pressure regimen due +to her hypotension in response to home doses of her medications. + on [**12-11**] the patients sbp dropped to the 80s and due to her +pain medications she was extremely lethargic, but arousable. a +picc line was placed because lack of access and she was bolused +250cc ns. the patients pressures responded and additional +narcotics were held due to her mental status. the patients +blood pressures continued to be labile and her clonidine patch +was increased to 0.3mg/24hr and her hydralazine was titrated +back to 100mg daily. the patient did require iv hydralazine prn +for control of her blood pressures initially, but was stablized +back on her home regimen. a possible component to the patients +malignant hypertension is likely due to osa. an inpatient sleep +study was performed overnight on [**12-13**] and the patient was sent +home on bipap for osa. the patient was continuned on her +admission hypertensive regimen. +. +2. abdominal pain: the etiology of her abdominal pain is +unclear, but has been a chronic issue for her. a ct scan was +performed that showed bowel wall changes that are likely +secondary to recent peritoneal dialysis and unrelated to pain. +the patient also had diarrhea, but stool studies were negative. +the patients pain was initially treated with hydromorphone, but +because of the patients lethargy on [**12-11**] they were initially +held. she continued to complain of severe abdominal pain. she +was slowly restarted back on her home regimen was 4mg po +hydromorphone q6 as her mental status improved. surgery was +consulted in regards to removal of her pd catheter, but given +that she may return to pd it was deferred to the outpatient +setting. + +3. ckd v from lupus nephritis: the patient was continued on hd +during her admission. she was also continued on her home +prednisone dose. she was closely followed by the renal team. +. +4. history of svc/subclavian vein thrombus: the patient was +found to have a subtherapeutic inr on admission 1.3. she was +started on a heparin gtt and continued on coumadin. the +patients heparin gtt was hled on [**12-10**] because of access +issues, but was restarted on [**12-11**] after her picc line was +placed. she was therapetuic the same day and her heparin gtt +was stopped. on discharge her coumadin was supratherapeutic +(4.7) and was held. she will have her inr checked at hd. +. +5. anemia: the patients hct slowly trended down. she was +guaiac negative and hemolysis labs were negative. she was +transfused 1u prbc at hd on [**12-12**]. she was also given epo at hd. + + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Systemic lupus erythematosus; Other and unspecified noninfectious gastroenteritis and colitis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other iatrogenic hypotension; Obstructive sleep apnea (adult)(pediatric); Hemangioma of intra-abdominal structures; Other chronic pain; Abdominal pain, unspecified site; Abnormal coagulation profile; Renal dialysis status; Personal history of venous thrombosis and embolism]" +109,136572.0,14860,2142-06-20,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",59,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,174489.0,14861,2142-07-04,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",47,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,174489.0,14861,2142-07-04,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",29,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,174489.0,14861,2142-07-04,14860,136572.0,2142-06-20,Discharge summary,"Admission Date: [**2142-6-18**] Discharge Date: [**2142-6-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2145**] +Chief Complaint: +Acute Onset Dyspnea + +Major Surgical or Invasive Procedure: +Dialysis + + +History of Present Illness: +Please see MICU note for full details. In brief this is a 24 +y.o. woman with SLE, ESRD on HD, hx malignant HTN, h/o SVC +syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, frequently admitted +with hypertensive urgency/emergency who was admitted with acute +onset dyspnea after 2 weeks without dialysis given to unable to +get transportation ? despite Dr. [**Last Name (STitle) 7473**] attempting to arrange +transport for her (? refused to come). She was admitted +therefore on [**6-18**] to micu with VS: T 100.4 HR 108 BP 240/180 RR +28 POx100 RA. She was treated with nitro gtt, labetolol gtt and +dilaudid-these gtts were stopped at 0700. In the micu she was +dialyzed with 1.7L fluid removal (though + 300cc given +tranfusion). Her SOB is improved. Her hct was also noted to be +low (18->from 22 [**2142-6-5**]) so transfused 2 units PRBC's, recent +EGD with gastric ulcer [**5-29**], guaiac negative in ED, no BM in +unit, hemolysis w/u negative. BP in icu 140/106 currently but of +note was hypotensive on HD to 86/62. She notes sob improved +rapidly on arrival. + +ROS: Currently she has no complaints. She notes at home her +abdominal pain is at baseline for her, felt mid epigastric, for +which she takes dilaudid 4mg up to [**Hospital1 **]. She has been getting HD +via right femoral catheter which is not painful, no discharge +from the sight. She denies HA, visual changes, cough, chest pain +or pressure, orthostatic changes, palpitations, nausea, +vomiting, constipation, diarrhea, melena, brbpr, dysuria, +hematuria, rash, swelling, orthopnea, pnd. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - T: 97.7, BP: 140/99 P: 88 R: 19 O2: 98% on RA +General: Sleeping comfortably but awakens easily, alert, +oriented x3 +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM, moon facies +Neck: supple, JVP flat, no LAD, full ROM, left EJ in place +Lungs: coarse BS throughout, no W/R/R, no decreased BS at bases + +CV: S1, S2 nl, no m/r/g appreciated +Abdomen: Firm, non-tender to palpation, no masses or +organomegally +Ext: Warm, well perfused, 1+ DP/PT, no clubbing, cyanosis or +edema +Neuro: a&o x3, motor [**5-15**] UE/LE bilaterally + + +Pertinent Results: +[**2142-6-18**] 05:28PM HCT-26.0*# +[**2142-6-18**] 11:38AM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-NORMAL MICROCYT-OCCASIONAL POLYCHROM-NORMAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-6-18**] 05:04AM GLUCOSE-85 UREA N-72* CREAT-10.4* SODIUM-139 +POTASSIUM-5.5* CHLORIDE-109* TOTAL CO2-14* ANION GAP-22* +[**2142-6-18**] 05:04AM LD(LDH)-264* TOT BILI-0.2 +[**2142-6-18**] 05:04AM CALCIUM-6.6* PHOSPHATE-6.5* MAGNESIUM-1.6 +[**2142-6-18**] 05:04AM HAPTOGLOB-142 +[**2142-6-18**] 05:04AM WBC-3.4* RBC-1.93* HGB-5.8* HCT-17.0* MCV-88 +MCH-30.0 MCHC-34.2 RDW-18.4* +[**2142-6-18**] 05:04AM PLT COUNT-97* +[**2142-6-18**] 01:34AM GLUCOSE-84 UREA N-70* CREAT-10.5*# SODIUM-136 +POTASSIUM-5.6* CHLORIDE-108 TOTAL CO2-14* ANION GAP-20 +[**2142-6-18**] 01:34AM estGFR-Using this +[**2142-6-18**] 01:34AM ALT(SGPT)-10 AST(SGOT)-39 ALK PHOS-108 TOT +BILI-0.2 +[**2142-6-18**] 01:34AM LIPASE-115* +[**2142-6-18**] 01:34AM ALBUMIN-3.2* CALCIUM-6.6* PHOSPHATE-6.8* +MAGNESIUM-1.7 +[**2142-6-18**] 01:34AM WBC-4.5 RBC-2.08* HGB-6.0* HCT-18.3* MCV-88 +MCH-28.6 MCHC-32.5 RDW-18.6* +[**2142-6-18**] 01:34AM NEUTS-78.5* LYMPHS-16.5* MONOS-3.0 EOS-1.4 +BASOS-0.6 +[**2142-6-18**] 01:34AM PLT COUNT-104* +[**2142-6-18**] 01:34AM PT-15.0* PTT-33.6 INR(PT)-1.3* + +Brief Hospital Course: +# Dyspnea: Pt's dypsnea improved on admission to the ED prior to +HD. Based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. Upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# Anemia: Pt's baseline 1 month ago noted to be low 30s, since +then her Hct has trended down to 22 several week prior to +admission. As she missed dialysis she was not able to reserve +her Eopgen which likely complicated her anemia. Pt underwent +hemolysis workup in the ICU which was ultimately negative. She +was given several units of PRBC and bumped her Hct +appropriately. She was noted to be guaiac negative on +examination. + +# Hypertension: Pt was initially admitted with hypertension. +Following transition to the floor she was placed on her home +regimen. She was noted to be hypotensive in dialysis which is +likely due to her being on Labetalol, Nitro gtt on dialysis. Pt +was discharged on her home BP regimen with follow up with her +nephrologist. + +# Chronic Abdominal Pain: Pt had noted some intermittent +abdominal pain which has been chronic. Lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. Pt was able to tolerate a PO diet prior to her +discharge. Pt was continued on her outpatient regimen of +Dilaudid, Fentanyl patch, Neurontin. + +# GE junction Ulcer: Pt was continued on her PPI regimen [**Hospital1 **]. + +# SLE: Pt was continued on her home regimen of Prednisone 4mg +daily + +# History of DVT: Pt had a sub-therapeutic INR on admission. She +was discharged on Warfarin 3mg daily. + +# ESRD on HD: Pt was admitted for dyspnea in the setting of +missing 2 weeks of HD. The renal team followed Ms. [**Known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. Pt was continued on Sevelamer and +Epogen. + +# Seizure D/O: Pt was continued on her home regimen of keppra. + +# Depression: Pt was continued on her home regimen of Celexa. + + +Medications on Admission: +1. Nifedipine 90 mg Tablet Sustained Release PO QAM +2. Nifedipine 60 mg Tablet Sustained Release PO QHS +3. Lidocaine 5 % transdermal one daily +4. Aliskiren 150 mg PO BID +5. Citalopram 20 mg PO DAILY (Daily). +6. Fentanyl 25 mcg/hr Patch Q72H (every 72 hours). +7. Prednisone 4mg PO DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Transdermal QSAT +9. Clonidine 0.3 mg/24 hr Patch Weekly Transdermal QSAT +10. Sevelamer HCl 400 mg Four (4) Tablet PO TID W/MEALS +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +13. Hydralazine 100 mg PO Q8H +14. Hydromorphone 2 mg 1-2 Tablets PO Q6H as needed for pain. +15. Pantoprazole 40 mg PO Q12H +16. LeVETiracetam 1,000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24 H (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: Malignant HTN, ESRD on HD, Shortness of breath +Secondary: Lupus + + +Discharge Condition: +Stable, afebrile + + +Discharge Instructions: +You were admitted to the hospital after you noticed some +shortness of breath. Whilst in the hospital you were noted to +have a low blood level (anemia) and you some fluid in your +lungs. We think your blood level was low because you were not +receiving your Epo shots, we think the fluid is from not +receiving dialysis. Before you were discharged from the hospital +your breathing was better. + +We recommend that you continue going to dialysis. + +We made no changes to your medications. + +If you notice any fevers, chills, nausea, vomiting, shortness of +breath, lightheadedness please return to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 +Provider: [**First Name4 (NamePattern1) **] [**Name Initial (NameIs) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-27**] 2:00 + + + [**Name6 (MD) **] [**Name8 (MD) **] MD [**MD Number(2) 2158**] + +",14,2142-06-18 03:11:00,2142-06-20 16:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ANEMIA," +# dyspnea: pts dypsnea improved on admission to the ed prior to +hd. based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# anemia: pts baseline 1 month ago noted to be low 30s, since +then her hct has trended down to 22 several week prior to +admission. as she missed dialysis she was not able to reserve +her eopgen which likely complicated her anemia. pt underwent +hemolysis workup in the icu which was ultimately negative. she +was given several units of prbc and bumped her hct +appropriately. she was noted to be guaiac negative on +examination. + +# hypertension: pt was initially admitted with hypertension. +following transition to the floor she was placed on her home +regimen. she was noted to be hypotensive in dialysis which is +likely due to her being on labetalol, nitro gtt on dialysis. pt +was discharged on her home bp regimen with follow up with her +nephrologist. + +# chronic abdominal pain: pt had noted some intermittent +abdominal pain which has been chronic. lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. pt was able to tolerate a po diet prior to her +discharge. pt was continued on her outpatient regimen of +dilaudid, fentanyl patch, neurontin. + +# ge junction ulcer: pt was continued on her ppi regimen [**hospital1 **]. + +# sle: pt was continued on her home regimen of prednisone 4mg +daily + +# history of dvt: pt had a sub-therapeutic inr on admission. she +was discharged on warfarin 3mg daily. + +# esrd on hd: pt was admitted for dyspnea in the setting of +missing 2 weeks of hd. the renal team followed ms. [**known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. pt was continued on sevelamer and +epogen. + +# seizure d/o: pt was continued on her home regimen of keppra. + +# depression: pt was continued on her home regimen of celexa. + + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Anemia of other chronic disease; Hyperpotassemia; Systemic lupus erythematosus; Abdominal pain, other specified site; Other chronic pain; Hypotension, unspecified; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Depressive disorder, not elsewhere classified; Personal history of venous thrombosis and embolism; Noncompliance with renal dialysis]" +109,136572.0,14860,2142-06-20,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",81,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,136572.0,14860,2142-06-20,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",89,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,136572.0,14860,2142-06-20,14807,158995.0,2142-02-26,Discharge summary,"Admission Date: [**2142-2-25**] Discharge Date: [**2142-2-26**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +altered mental status, solmolence, and relative hypotension + +Major Surgical or Invasive Procedure: +none, HD per schedule on the day of discharge, transfused 1u +PRBC + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, hx of +malignant HTN admitted with change in mental status. Patient +missed HD on [**2142-2-24**] and was found unresponsive and diaphoretic +by mother this morning after she took some dilaudid. EMS was +called, 1 mg of narcan was administered with slight improvement +in mental status. On arrival to the ED her vitals were 112/64 +62 16 99RA + + + +she was noted to be hyperkalemic in the absence of EKG changes +and was given calcium, D5, 10U regular insulin, 30 mg po +kayxalate and repeat K was 5.4. ABG: 7.29/38/199. Repeat +glucose was 41 and 1amp D50 was given. + + + +She was sent to the ICU for monitoring. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including [**Month/Year (2) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +HR: 80 (79 - 80) bpm +BP: 127/59(76) {127/59(76) - 139/64(82)} mmHg +RR: 34 (21 - 34) insp/min +SpO2: 100% +Heart rhythm: SR (Sinus Rhythm) + +Physical Examination +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact + + +Pertinent Results: +[**2142-2-25**] 01:50PM PT-14.9* PTT-36.8* INR(PT)-1.3* +[**2142-2-25**] 01:50PM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL STIPPLED-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-2-25**] 01:50PM WBC-5.0 RBC-2.21* HGB-6.4* HCT-20.7* MCV-94 +MCH-29.1 MCHC-31.1 RDW-19.6* +[**2142-2-25**] 10:30PM GLUCOSE-87 UREA N-66* CREAT-8.4* SODIUM-142 +POTASSIUM-5.9* CHLORIDE-110* TOTAL CO2-16* ANION GAP-22* + +HISTORY: Altered mental status. Evaluate underlying for +pneumonia. + +UPRIGHT PORTABLE CHEST: Comparison is made to [**2-14**] and +[**2142-2-19**], exams. + +Study is slightly limited by patient motion. In the interval, +the degree of +pulmonary edema appears improved with slightly decreased +prominence of the +pulmonary vascularity. There is unchanged extensive retrocardiac +consolidation +obscuring the majority of the left hemidiaphragm with persistent +blunting of +the left CP angle, likely related to small effusion. Exam is +otherwise +unchanged from prior with persistent cardiomegaly. A catheter is +seen +projecting over the abdomen, partially imaged. + +IMPRESSION: + +Slight improvement in pulmonary edema with persistent +retrocardiac opacity, +which again may represent atelectasis versus underlying +pneumonia. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted hypotension and +decreased mental status. Hypotension and altered mental status +were in the setting of excessive narcotic use. Patient's +narcotics were held, pressors returned to [**Location 213**] and patient was +mentating fine. Hct was below baseline and patient was +transfused 1u PRBC and was given HD before discharge. Patient is +to continue anti-hypertensive medications as previously +scheduled. Patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# Change in mental status: Resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +Patient received 1 dose of narcan with slight improvement in BP +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# Hypertension ?????? resumed outpatient regimen. Patient did not +have any hypertensive episodes requiring hydralizine 10mg IV. + +# Hypotension: resolved, Patient normotensive on arrival to ICU. + Relative hypotension likely due to dilaudid. Other +considerations include sepsis, although patient without +objective signs of infection. Held pain medications and +hypotension resolved. Resumed hypertensive medications. + +# Abdominal pain ?????? from previous peritoneal [**Location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# Hyperkalemia: Likely due to missed HD session. She received +calcium, D5, insulin and kayexalate in ED. HD in am + +ESRD: Renal following, had HD the day of discharge, transfused +while there. Will continue normal schedule as an outpatient +with HD T/Th/F this week. + +# Metabolic Acidosis: likely due to renal failure and missed HD. + + +# SLE: continued prednisone at 4 mg PO daily. + +# OSA: CPAP for sleep with 7 pressure, however patient refuses. +Continued to offer as inpatient. Should try to follow up with +sleep medicine. + + +Medications on Admission: +Prednisone 4mg qd +Citalopram 20 mg daily +Gabapentin 300 mg [**Hospital1 **] +Warfarin 4mg daily +Pantoprazole 40 mg qd +Clonidine 0.1 mg/24 QWED +Clonidine 0.3 mg/24 hr QWED +Labetalol 900 mg tid +Nifedipine 90 mg qd +Aliskiren 150 mg [**Hospital1 **] +Hydralazine 100 mg q8h +Morphine 7.5 mg q8h prn pain + + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Labetalol 100 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +9. Sevelamer HCl 400 mg Tablet Sig: Two (2) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +narcotic overdose +relative hypotension +anemia + +Secondary: +ESRD on HD [**2-12**] SLE +malignant hypertension + + +Discharge Condition: +stable - received HD prior to discharge + + +Discharge Instructions: +You were admitted for altered mental status after missing +hemodialysis. It was likely from the dilaudid you took as well +as missing your scheduled [**Month/Day (2) 2286**]. You were also relatively +hypotensive in the setting of excessive narcotic medicaiton +usage. Narcotic medications were held and hypotension and +altered mental status resolved. Please use narcotic medications +with caution. You are recommended to use morphine for pain +control rather than dilaudid. + +No medication changes were made. + +Please return to the ED if you have any altered mental status or +miss [**First Name (Titles) **] [**Last Name (Titles) 2286**] or have symptoms such as vision changes or +headache from your history of malignant hypertension. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) 488**] [**Last Name (NamePattern4) 43496**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-3-20**] 3:00 + +HD as previously scheduled + + + +Completed by:[**2142-2-26**]",114,2142-02-25 15:49:00,2142-02-26 16:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALTERED MENTAL STATUS," +24 yo woman with hx of sle, ersd on hd, admitted hypotension and +decreased mental status. hypotension and altered mental status +were in the setting of excessive narcotic use. patients +narcotics were held, pressors returned to [**location 213**] and patient was +mentating fine. hct was below baseline and patient was +transfused 1u prbc and was given hd before discharge. patient is +to continue anti-hypertensive medications as previously +scheduled. patient was encouraged to take less pain medications +and to use morphine (already previously written for) rather than +dilaudid for pain control. + +# change in mental status: resolved, patient took dilaudid this +morning and was noticed to be unresponsive shortly thereafter. +patient received 1 dose of narcan with slight improvement in bp +and mental status. patient without fevers or leuckocytosis +which argue against infection. + +# hypertension ?????? resumed outpatient regimen. patient did not +have any hypertensive episodes requiring hydralizine 10mg iv. + +# hypotension: resolved, patient normotensive on arrival to icu. + relative hypotension likely due to dilaudid. other +considerations include sepsis, although patient without +objective signs of infection. held pain medications and +hypotension resolved. resumed hypertensive medications. + +# abdominal pain ?????? from previous peritoneal [**location 2286**] hematoma ?????? +pain under control +patient should use morphine instead of dilaudid + +# hyperkalemia: likely due to missed hd session. she received +calcium, d5, insulin and kayexalate in ed. hd in am + +esrd: renal following, had hd the day of discharge, transfused +while there. will continue normal schedule as an outpatient +with hd t/th/f this week. + +# metabolic acidosis: likely due to renal failure and missed hd. + + +# sle: continued prednisone at 4 mg po daily. + +# osa: cpap for sleep with 7 pressure, however patient refuses. +continued to offer as inpatient. should try to follow up with +sleep medicine. + + + ","PRIMARY: [Poisoning by other opiates and related narcotics] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Thrombotic microangiopathy; Other primary cardiomyopathies; Acidosis; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Altered mental status; Other iatrogenic hypotension; Accidental poisoning by other opiates and related narcotics; Hyperpotassemia; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Nontraumatic hematoma of soft tissue; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,136572.0,14860,2142-06-20,14806,113189.0,2142-02-17,Discharge summary,"Admission Date: [**2142-2-14**] Discharge Date: [**2142-2-17**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 5119**] +Chief Complaint: +Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +From admission note: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome admitted with HTN and SOB in the setting +of missed HD. The patient reported missing HD yesterday because +she thinks she is being overdiuresed. She reports persistent +pain at site of rectus sheath hematoma. Denies N/V/D. + +Pt recently admitted from [**Date range (1) 13924**] with consistent abdominal +pain at the site of her known left abdominal wall hematoma, +hypertensive to 230's and hyperkalemic to 6.2 after missing her +last two dialysis sessions. At this time the pt. was dialyzed, +received a blood transfusion, and was administered her daily +antihypertensive medications. Pt. left AMA after her +transfusion despite the primary team's concerns to look for an +active area of bleeding. + +In the ED, patient complain of mild dyspnea, sating well on RA. +CXR mild volume overload. KUB with no evidence of obstruction. +She was started on a labetalol gtt. ECG - RAD, LVH no change +from prior. HCT stable at 21. The renal team evaluated pt and +recommended HD, however the patient refused. She was transferred +to ICU for BP control. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Gen: sleeping comfortably, easily awoken by verbal stimuli +HEENT: L eye prosthetic non-reactive, R pupil reactive, MMM +Heart: S1S2 RRR, III/VI SEM throughout the precordium +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, mild L TTP, no +rebound/guarding +Ext: no edema, no clubbing, WWP. R femoral HD [**Last Name (un) **] in place +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +[**2142-2-14**] 07:40AM WBC-3.9* RBC-2.38* HGB-7.0* HCT-21.3* MCV-90 +MCH-29.5 MCHC-33.0 RDW-18.9* +[**2142-2-14**] 07:40AM NEUTS-74.9* LYMPHS-18.7 MONOS-3.1 EOS-3.0 +BASOS-0.2 +[**2142-2-14**] 07:40AM PLT COUNT-101* +[**2142-2-14**] 07:40AM PT-16.3* PTT-36.6* INR(PT)-1.5* +[**2142-2-14**] 07:40AM CK-MB-6 +[**2142-2-14**] 07:40AM cTropnT-0.09* +[**2142-2-14**] 07:40AM LIPASE-80* +[**2142-2-14**] 07:40AM ALT(SGPT)-34 AST(SGOT)-72* CK(CPK)-120 ALK +PHOS-124* TOT BILI-0.4 +[**2142-2-14**] 07:40AM GLUCOSE-85 UREA N-32* CREAT-7.0* SODIUM-142 +POTASSIUM-4.3 CHLORIDE-110* TOTAL CO2-19* ANION GAP-17 +[**2142-2-14**] 07:44AM LACTATE-1.3 + +[**2142-2-14**] CXR: Stable cardiomegaly with mild CHF and a small left +pleural effusion. Left basilar air space disease which may +represent pneumonia. Clinical correlation and a follow up chest +x-ray to clearance is recommended. + +[**2142-2-14**] KUB: 1. Nonspecific bowel gas pattern with no evidence of +obstruction. 2. Left basilar airspace disease which may +represent pneumonia and a small left pleural effusion. Please +ensure follow-up to clearance. + + +Brief Hospital Course: +24 y.o female with SLE, ESRD on HD and malignant hypertension +who presents with HTN and SOB aftering missing HD. +. +# Malignant hypertension/hypertensive urgency: The patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and HD compliance. Has previously presented with +BP up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. Pt was treated per OMR +hypertensive protocol created by the patient's primary +providers, with a goal SBP of 160-180. With short course of IV +antihypertensives and hemodialysis, pt's BP fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# ESRD: Pt was followed by the renal service and underwent HD +without any complications. Pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting HD. She will discuss this further +with the Renal team as an outpatient. +. +# SLE: Pt was continued on her home dose of prednisone with no +sign of SLE flair. +. +# Coagulopathy/history of DVT: Patient on lifetime +anticoagulation for hx of multiple thrombotic events. Pt was +continued on coumadin. +. +# Pain management: Pt was treated with PO dilaudid for her +abdominal pain, as recommended per her OMR protocol. She asked +for IV dilaudid multiple times but there was no clinical +indication. She was also continued on gabapentin. +. +# Anemia: Secondary to AOCD and renal failure. The patietns Hct +remained stable in the low 20s during admission. No PRBC +infusions were needed. +. +# Depression/anxiety: Continued Celexa, clonazepam 0.5mg [**Hospital1 **] + +Medications on Admission: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QWED (every Wednesday). +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a + +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) + +Capsule PO once a month. + +Discharge Medications: +1. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +8. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO TID (3 times +a day). +9. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +10. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain. +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Malignant Hypertension + +Secondary: SLE, End stage renal disease on hemodialysis, SVC +syndrome + + +Discharge Condition: +Stable. SBP in 160s. + + +Discharge Instructions: +You were admitted with dangerously high hypertension and some +shortness of breath in the setting of missing several dialysis +sessions. You were admitted and treated with your usual regimen +of blood pressure meds and a short course of IV meds. With +dialysis, your symptoms improved. + +You also had some abdominal pain, which was well controlled on +your usual pain medications. + +We made no changes to your medications. Please take everything +as prescribed. + +Please call your PCP or return to the hospital if you develop +any headaches, visual changes, confusion or chest pain, or any +other concerning symptoms. + +Followup Instructions: +Please schedule a follow up with Dr [**Last Name (STitle) **] in [**Month (only) 958**] as +scheduled. + + [**First Name7 (NamePattern1) 1569**] [**Initial (NamePattern1) **] [**Name8 (MD) **] MD [**MD Number(2) 5122**] + +Completed by:[**2142-2-21**]",123,2142-02-14 10:42:00,2142-02-17 18:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 y.o female with sle, esrd on hd and malignant hypertension +who presents with htn and sob aftering missing hd. +. +# malignant hypertension/hypertensive urgency: the patient has a +well-documented history of paroxysmal hypertension believed to +possibly be related to pain, anxiety, narcotic withdrawal and +poor medication and hd compliance. has previously presented with +bp up to 260/160 but most often without evidence of end-organ +ischemia, as she did for this admission. pt was treated per omr +hypertensive protocol created by the patients primary +providers, with a goal sbp of 160-180. with short course of iv +antihypertensives and hemodialysis, pts bp fell appropriately +and was well maintained on oral outpt regimen of clonidine, +labetalol, aliskiren, nifedipine. +. +# esrd: pt was followed by the renal service and underwent hd +without any complications. pt states she would like to +reconsider peritoneal dialysis as she is experiencing increased +fatigue since instituting hd. she will discuss this further +with the renal team as an outpatient. +. +# sle: pt was continued on her home dose of prednisone with no +sign of sle flair. +. +# coagulopathy/history of dvt: patient on lifetime +anticoagulation for hx of multiple thrombotic events. pt was +continued on coumadin. +. +# pain management: pt was treated with po dilaudid for her +abdominal pain, as recommended per her omr protocol. she asked +for iv dilaudid multiple times but there was no clinical +indication. she was also continued on gabapentin. +. +# anemia: secondary to aocd and renal failure. the patietns hct +remained stable in the low 20s during admission. no prbc +infusions were needed. +. +# depression/anxiety: continued celexa, clonazepam 0.5mg [**hospital1 **] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Thrombotic microangiopathy; Systemic lupus erythematosus; Anemia in chronic kidney disease; Thrombocytopenia, unspecified; Obstructive sleep apnea (adult)(pediatric); Nontraumatic hematoma of soft tissue; Dysthymic disorder; Noncompliance with renal dialysis; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +109,136572.0,14860,2142-06-20,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",33,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,136572.0,14860,2142-06-20,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",15,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,136572.0,14860,2142-06-20,14802,140167.0,2141-12-23,Discharge summary,"Admission Date: [**2141-12-18**] Discharge Date: [**2141-12-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Malignant hypertension + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24 year old female with ESRD on HD, SLE, malignant HTN presents +with headache and abdominal pain beginning this morning. Patient +had her hemodialysis day before yesterday. She has had multiple +admissions to [**Hospital1 18**] with hypertensive urgency with symptoms of +headache and abdominal pain. Has had extensive work-up for +abdominal pain including ex-lap on [**2141-10-27**] which was negative. +Patient states that her headache and abdominal pain are similar +in characteristics to her previous admission. Patient denies any +fever, chills, nightsweats, chest pain, shortness of breath, +abdominal pain, nausea, vomitting, diarrhea, constipation, blood +in stool, dysuria, hematuria, change in vision, hearing, +weakness or numbness. + +In the ED, initial vitals were T97, BP253/170, HR100, RR24 +100%RA. Was initially given 10mg IV Labetalol once and then +started on drip at 2mg/hour. She also received hydralazine IV 10 +mg once and 2 inch nitropaste. She morphine 4mg once for pain +and 4mg Zofran for nausea. Her BP elevated as high as 270/174 +and his labetolol was switched to nicardipine 1mg/kg/min. + +On arrival to the MICU her vitals were T 96.4 HR 99 BP 175/120 +RR 15 100%RA. Patient was comfortable. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera +injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +. +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +Vitals: 97.5 122/80 88 18 100%RA. +Gen: sleeping, easily arousable, appears comfortable. +HEENT: AT/NC, L eye prosthetic non-reactive, R pupil reactive, +MMM. +Heart: S1S2 RRR, III/VI SEM heard best at apex, + S3 +Pulm: CTA b/l, no w/r/r. +Abd: normal bowel sounds, midline scar well-healed, soft, +nontender, prior PD site with dry dressing, patient with +tenderness to palpation over prior PD cath site, no +guarding/rebound +Ext: no edema, no clubbing, WWP. R femoral HD catheter in place. + +Neuro: following commands, answers appropriately, [**5-15**] motor +strength, sensation is intact. + + +Pertinent Results: +Admission: +[**2141-12-18**] 02:00AM BLOOD WBC-5.8 RBC-3.30* Hgb-10.1* Hct-30.3* +MCV-92 MCH-30.7 MCHC-33.5 RDW-20.7* Plt Ct-199 +[**2141-12-18**] 02:00AM BLOOD PT-14.2* PTT-32.1 INR(PT)-1.2* +[**2141-12-18**] 02:00AM BLOOD UreaN-35* Creat-5.0* Na-138 K-5.5* Cl-103 +HCO3-21* AnGap-20 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-18**] 02:00AM BLOOD Lipase-73* +[**2141-12-18**] 02:00AM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2141-12-19**] 06:45AM BLOOD Calcium-8.1* Phos-5.1* Mg-1.8 +[**2141-12-18**] 03:52PM BLOOD dsDNA-NEGATIVE +[**2141-12-18**] 03:52PM BLOOD CRP-11.5* +[**2141-12-18**] 03:52PM BLOOD C3-68* C4-19 +[**2141-12-20**] 12:09PM BLOOD Type-ART pO2-158* pCO2-42 pH-7.36 +calTCO2-25 Base XS--1 +[**2141-12-18**] 02:08AM BLOOD pO2-52* pCO2-38 pH-7.39 calTCO2-24 Base +XS--1 Comment-GREEN TOP +[**2141-12-20**] 12:09PM BLOOD Lactate-0.9 +[**2141-12-18**] 02:08AM BLOOD Glucose-68* Lactate-1.3 Na-140 K-4.8 +Cl-103 + +[**2141-12-23**] 03:00PM BLOOD WBC-4.7 RBC-2.35* Hgb-7.1* Hct-22.3* +MCV-95 MCH-30.3 MCHC-31.9 RDW-20.6* Plt Ct-131* +[**2141-12-23**] 12:55AM BLOOD PT-14.7* PTT-66.2* INR(PT)-1.3* +[**2141-12-18**] 03:52PM BLOOD ESR-21* +[**2141-12-23**] 03:00PM BLOOD Glucose-97 UreaN-42* Creat-6.6* Na-138 +K-4.3 Cl-106 HCO3-23 AnGap-13 +[**2141-12-18**] 02:00AM BLOOD ALT-16 AST-69* CK(CPK)-89 AlkPhos-109 +TotBili-0.4 +[**2141-12-23**] 03:00PM BLOOD Calcium-8.6 Phos-4.5 Mg-1.8 +[**2141-12-18**] 04:23PM URINE Color-Straw Appear-Hazy Sp [**Last Name (un) **]-1.008 +[**2141-12-18**] 04:23PM URINE Blood-NEG Nitrite-NEG Protein-100 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.5 Leuks-NEG +[**2141-12-18**] 04:23PM URINE RBC-<1 WBC-<1 Bacteri-FEW Yeast-NONE +Epi-12 TransE-<1 + +Micro: +Blood Cx- [**12-18**]: No growth +Urine Cx- [**12-18**]: No growth + +[**12-18**] TTE +The left atrium and right atrium are normal in cavity size. A +possible secundum type atrial septal defect is seen by color +Doppler (clip [**Clip Number (Radiology) **]) There is severe symmetric left ventricular +hypertrophy with normal cavity size and regional/global systolic +function. There is no significant resting LVOT gradient, but a +mild gradient (30mmHg peak) is seen with Valsalva manuever. +Right ventricular chamber size and free wall motion are normal. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion and no aortic stenosis. Mild (1+) aortic +regurgitation is seen. The mitral valve appears structurally +normal with trivial mitral regurgitation. There is mild +pulmonary artery systolic hypertension. There is a small +circumferential pericardial effusion without echocardiographic +signs of tamponade. + +IMPRESSION: Marked symmetric left ventricular hypertrophy with +normal regional/global systolic function and mild inducible LVOT +gradient. Mild aortic regurgitation. Mild pulmonary artery +systolic hypertension. Possible secundum type atrial septal +defect. +Compared with the prior study (images reviewed) of [**2141-10-19**], a +possible secundum type atrial septal defect is now suggested. +If clinically indicated, a follow-up study with saline contrast +and/or a TEE would be better able to characterize the possible +atrial septal defect. + +CLINICAL IMPLICATIONS: +Based on [**2140**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. + +[**12-18**] CXR +IMPRESSION: +1. Cardiomegaly with findings suggestive of mild pulmonary +edema. +2. Bibasilar linear opacities suggesting atelectasis, although +developing +pneumonia cannot be excluded. +3. No evidence of free intraperitoneal air. + +[**12-20**] MRV +IMPRESSION: +No appreciable change since the MRV chest exam dated [**2141-5-30**]. SVC is +patent. Again seen is occlusion of the right internal jugular +and left +brachiocephalic veins. Right external jugular vein is provides +the major +venous drainage from the neck. + + +Brief Hospital Course: +24 year old Female with SLE, ESRD on HD and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ED. + +1. Malignant Hypertension: The patient had her hemodialysis two +days prior to admission. Initially in the ED her BP was 253/170. +She was given 10mg IV Labetalol and started on a labatelol drip. +She also received hydralazine IV 10 mg once and 2 inches of +nitropaste. She had morphine 4mg and 4mg Zofran for nausea. Her +BP remained elevated so she was switched to nicardipine +1mg/kg/min. The patient was transferred to the MICU. In the ICU +she was continued on the Nicardapine drip and her pressures +decreased to 175/120. Nephrology was consulted and dialysis +initiated in the AM. The Nicardapine drip dc'd on [**12-19**] and pt +transferred to floor. + +While on the floor the patient had question of angioedema and +markedly elevated BP. She was readmitted to the MICU on +[**2141-12-20**]. Patient's Aliskerin was also held for conern for +angioedema. The renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. The patient's PD catheter was removed. The patient +was briefly on a nitro drip for hypertension. The patient's +nifedepine was increased to 120mg. The patient was transferred +to the floor with stable blood pressures, BP 124/72 on [**12-21**]. + +The morning of [**12-22**], the patient was noted to have a BP up to +247/120 at 0800. Hypertension persisted throughout the morning +with BPs 210s-240s systolic. HR during this time was in the 90s. +She received a total of 60 mg IV hydralazine over the course of +the morning as well as 0.1 mg PO clonidine. She was also given +her normal AM BP meds and restarted on aliskarin. Due to +persistent hypertension, she was transferred to the ICU for +further care. + +On arrival to the ICU, the patient reported severe abdominal +pain over the site of recently removed PD catheter. She denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. She reports bilateral calf cramping but no +leg swelling. She denies any difficulty breathing or chest pain. +She took her AM BP meds without difficulty. Her blood pressure +decreased to 130s-140s/60s without further intervention. She was +transferred back to the floor on [**12-23**] and signed out AMA. + +2. Angioedema: +On [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ENT. The patient reported that her face is more +swollen which was confirmed by her mother on the floor. The +patient was give lasix IV as she has been unable to have any +negative filtration with HD. The patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. Her +tekturna was discontinued for concern that it might be causing +angioedema. She denied difficulty with her breathing at that +time, but was very somnulent. On arrival to the MICU her vitals +were stable and oxygenating well at 100% on face mask. The +patient's airway was supported with a nasal trumpet. The patient +underwent MRV that showed no progression of her clot. Patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. She was treated with prednisone and +decadron, famotidine and benadryl for angioedema. The patient +was maintained on her heparin drip for her SVC syndrome. + +3. Abdominal Pain: The patient has had extensive prior workup +that has been unrevealing. The Transplant surgery team removed +the PD cath on [**12-21**]. She continued to have abdominal pain +post-op. She was continued on PO dilaudid 2mg po prn. She +continuned to complain of abdominal pain throughout her +admission and continued to requested IV dilaudid. + +4. ESRD: The patient is on a T/Th/Sat schedule. She was closely +followed by the renal team. She had dialysis on [**12-19**]. The +patient's tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. The patient also had her PD catheter removed on [**12-21**] +secondary to chronic abdominal pain. The patient was scheduled +to have dialysis on [**12-23**]. + +5. Hx of SVC/brachiocephalic DVT: Her coumadin was held during +last admission for supratherapeutic INR. She was admitted with a +subtherpeutic INR of 1.2 She was started on a heparin drip. She +was also started on Coumadin 2mg PO qday, but was held on [**12-19**] +in prep her PD catheter removal. She was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by IR. +However, the patient signed out AMA and thus it was not placed. + + +6. Anxiety: Pt recently saw psychiatrist who started her on +Celexa. She was continued on Celexa 20mg PO daily. + +7. Anemi of CKDa: The patient's Hct was 30.3 on admission. It +trended down to 22.3 on discharge when she left AMA. There was +no evidence of active, acute bleeding. THis is likely seoncdary +to her ESRD. The patient was closely monitored. + +8. Systemic Lupus Erythematosis: Rheumatology was consulted and +does not suspect acute flare and dsDNA, C3, C4 nl, ESR and CRP +slightly elevated. Her Echo did not suggest worsening +pericarditis. She was continued on her home prednisone dose of +4mg daily. + +9. Obstructive Sleep Apnea: CPAP for sleep with 7 pressure. + + +Medications on Admission: +Aliskiren 150 mg [**Hospital1 **] +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Warfarin held on discharge [**2141-12-14**] due to supratherap INR + +Discharge Medications: +As patient signed out AMA, no medications were issued. She was +told to resume her admission medications, however no +instructions were taken by the patient. + +Discharge Disposition: +Home + +Discharge Diagnosis: +1) Hypertensive urgency +2) Abdominal pain +3) End stage renal disease on hemodialysis +4) Venous thromboembolism + + +Discharge Condition: +Signed out AMA + + +Discharge Instructions: +Pt signed out AMA + +Return to the hospital with any concerning symptoms. Be sure to +call your doctor's office on [**Month/Day/Year 766**] to arrange hemodialysis and +review your medications and discuss follow-up plan. + +Followup Instructions: +Follow-up with your Dr. [**Last Name (STitle) **] next week, and call [**Last Name (STitle) 766**] to +arrange your hemodialysis. + + + +Completed by:[**2141-12-26**]",179,2141-12-18 03:50:00,2141-12-23 19:51:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24 year old female with sle, esrd on hd and malignant +hypertension presents with abdominal pain and headache +consistent with her usual hypertensive urgency and was found to +be in hypertensive urgency in ed. + +1. malignant hypertension: the patient had her hemodialysis two +days prior to admission. initially in the ed her bp was 253/170. +she was given 10mg iv labetalol and started on a labatelol drip. +she also received hydralazine iv 10 mg once and 2 inches of +nitropaste. she had morphine 4mg and 4mg zofran for nausea. her +bp remained elevated so she was switched to nicardipine +1mg/kg/min. the patient was transferred to the micu. in the icu +she was continued on the nicardapine drip and her pressures +decreased to 175/120. nephrology was consulted and dialysis +initiated in the am. the nicardapine drip dcd on [**12-19**] and pt +transferred to floor. + +while on the floor the patient had question of angioedema and +markedly elevated bp. she was readmitted to the micu on +[**2141-12-20**]. patients aliskerin was also held for conern for +angioedema. the renal team removed her tunneled dialysis +catheter that had a cuff out, and replaced it with a temporary +femoral line. the patients pd catheter was removed. the patient +was briefly on a nitro drip for hypertension. the patients +nifedepine was increased to 120mg. the patient was transferred +to the floor with stable blood pressures, bp 124/72 on [**12-21**]. + +the morning of [**12-22**], the patient was noted to have a bp up to +247/120 at 0800. hypertension persisted throughout the morning +with bps 210s-240s systolic. hr during this time was in the 90s. +she received a total of 60 mg iv hydralazine over the course of +the morning as well as 0.1 mg po clonidine. she was also given +her normal am bp meds and restarted on aliskarin. due to +persistent hypertension, she was transferred to the icu for +further care. + +on arrival to the icu, the patient reported severe abdominal +pain over the site of recently removed pd catheter. she denied +any headache, nausea, vomiting, diarrhea, constipation, or lower +extremity swelling. she reports bilateral calf cramping but no +leg swelling. she denies any difficulty breathing or chest pain. +she took her am bp meds without difficulty. her blood pressure +decreased to 130s-140s/60s without further intervention. she was +transferred back to the floor on [**12-23**] and signed out ama. + +2. angioedema: +on [**12-20**] the patietn developed facial swelling and evidence of +angioedema by ent. the patient reported that her face is more +swollen which was confirmed by her mother on the floor. the +patient was give lasix iv as she has been unable to have any +negative filtration with hd. the patient was started on decadron +10mg q8hr, famotidine, diphenhydramine for the edema. her +tekturna was discontinued for concern that it might be causing +angioedema. she denied difficulty with her breathing at that +time, but was very somnulent. on arrival to the micu her vitals +were stable and oxygenating well at 100% on face mask. the +patients airway was supported with a nasal trumpet. the patient +underwent mrv that showed no progression of her clot. patient +was diuresed with lasix and dialysis with significant +improvement in her symptoms. she was treated with prednisone and +decadron, famotidine and benadryl for angioedema. the patient +was maintained on her heparin drip for her svc syndrome. + +3. abdominal pain: the patient has had extensive prior workup +that has been unrevealing. the transplant surgery team removed +the pd cath on [**12-21**]. she continued to have abdominal pain +post-op. she was continued on po dilaudid 2mg po prn. she +continuned to complain of abdominal pain throughout her +admission and continued to requested iv dilaudid. + +4. esrd: the patient is on a t/th/sat schedule. she was closely +followed by the renal team. she had dialysis on [**12-19**]. the +patients tunneled dialysis catheter had a cuff that was out +and qas subsequently replaced with a temporary femoral line on +[**12-21**]. the patient also had her pd catheter removed on [**12-21**] +secondary to chronic abdominal pain. the patient was scheduled +to have dialysis on [**12-23**]. + +5. hx of svc/brachiocephalic dvt: her coumadin was held during +last admission for supratherapeutic inr. she was admitted with a +subtherpeutic inr of 1.2 she was started on a heparin drip. she +was also started on coumadin 2mg po qday, but was held on [**12-19**] +in prep her pd catheter removal. she was continuned on the +heparin drip and her coumadin continued to be held in +preparation for placement of a tunneled dialysis catheter by ir. +however, the patient signed out ama and thus it was not placed. + + +6. anxiety: pt recently saw psychiatrist who started her on +celexa. she was continued on celexa 20mg po daily. + +7. anemi of ckda: the patients hct was 30.3 on admission. it +trended down to 22.3 on discharge when she left ama. there was +no evidence of active, acute bleeding. this is likely seoncdary +to her esrd. the patient was closely monitored. + +8. systemic lupus erythematosis: rheumatology was consulted and +does not suspect acute flare and dsdna, c3, c4 nl, esr and crp +slightly elevated. her echo did not suggest worsening +pericarditis. she was continued on her home prednisone dose of +4mg daily. + +9. obstructive sleep apnea: cpap for sleep with 7 pressure. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Mechanical complication due to peritoneal dialysis catheter; ; Unspecified disease of pericardium; Angioneurotic edema, not elsewhere classified; Abdominal pain, other specified site; Systemic lupus erythematosus; ; Anemia in chronic kidney disease; Dysthymic disorder; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of steroids; Long-term (current) use of anticoagulants; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other antihypertensive agents causing adverse effects in therapeutic use]" +109,136572.0,14860,2142-06-20,14803,135923.0,2142-01-12,Discharge summary,"Admission Date: [**2142-1-8**] Discharge Date: [**2142-1-13**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Hypertensive Urgency and HA + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with HA in the setting of hypertension. Upon +arrival to the ED, her vitals were 284/140, HR 67, RR 28, 100% +on 4LNC. She was started on a nicardipine drip. She denied +shortness of breath or chest pain. She is due for HD today. She +has a left groin catheter which was recently placed [**2141-12-21**] and +is causing her pain. She was also given dilaudid IV 1 mg x 2 +with some relief. CXR was performed and showed no pulmonary +edema. +. +Upon arrival to the MICU, patient denies HA, CP, SOB, fevers, +chills. Patient reports mild abdominal pain at sight of left +anterior abdominal wall hematoma and left groin pain at site of +femoral HD line. She reports that she was taking her medications +as directed, including coumadin for SVC thrombus. + +Briefly, 24 yo F with ESRD on HD, SLE, malignant HTN admitted +for HA in the setting of HTN to 284/140 in ED. Initially, she +was treated with a nicardipine gtt to control her BP. Her +cardiac enzymes were flat, no new ECG changes. She was started +on a heparin gtt with transition to coumadin for a SVC +thrombosis. HTN secondary to med noncompliance. She was +restarted on her oral BP. She missed her PM meds yesterday, so +nicardipine was restarted, and then turned off this AM. She +received all her AM BP meds. Her BPs have been in the 160s/90s. +She had no neurological deficits. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: 176/105, 87, 18, 100% RA +General Appearance: Well nourished, No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: 2/6 systolic murmur LUSB +Respiratory / Chest: (Breath Sounds: Clear : ) +Abdominal: left ant wall abd hematoma, TTP +Extremities: Right: Trace, Left: Trace, left fem HD line without +oozing or drainage +Skin: Warm +Neurologic: AAO x 3 + + +Pertinent Results: +[**2142-1-8**] 05:15AM PT-13.7* PTT-33.6 INR(PT)-1.2* +[**2142-1-8**] 05:15AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-1+ SPHEROCYT-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-1+ STIPPLED-OCCASIONAL TEARDROP-1+ +BITE-NORMAL FRAGMENT-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2142-1-8**] 05:15AM cTropnT-0.08* +[**2142-1-8**] 05:15AM CK(CPK)-119 +[**2142-1-8**] 04:12PM PTT-120.8* +[**2142-1-8**] 10:41PM PTT-144.8* +[**2142-1-8**] 02:55PM CK-MB-NotDone cTropnT-0.06* + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. Patient was initially observed in the MICU +and placed on a nicardipine drip. Patient was stablized on home +medicaitons, suggesting medication non-compliance. Additionally, +patient presented subtheraputic on coumadin for SVC thrombosis. +Patient was started on heparin ggt. After the nicardipine drip +was turned off, patient was called out to the floor. Heparin +drip was continued until INR [**2-13**]. Pressures were managed to her +baseline. Pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with Narcan. Patient received dialysis 3x/wk as per outpatient +schedule. + +# Hypertension: Pt with extensive history of repeated admissions +for hypertension. Patient's BP improved with nicardipine drip +and after HD off drip on home PO medication regimen. Resumed +oral antihypertensives with improved BP control. HTn likely from +renal disease, possible medication noncompliance, lupus. No +evidence of MI. Continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. Renal increased +clonidine patch, and added Nicardipine with improvement of BP +control. Pt is to follow up with an appointment in the next week +to establish care at [**Company 191**], and to re-check her BP and adjust +medications further. + +# SLE: Stable, continued prednisone at 4 mg PO daily. + +# Left groin pain. Permanent HD line was placed on [**12-25**]. Line +and hematoma from prior peritoneal line on abdomen okay. No +leukocytosis or fevers to suggest infection. Patient was +oversedated on Dilaudid and had episode of oxygen desaturation +which was reversed with Narcan. Patient was solmolent with +morphine SR so that was d/c'ed as well, patient was given +standing tylenlol and Morphine IR PRN. Transplant surgery +removed remaining sutures today from L groin. Pt has a follow-up +appointment in the next week with Dr. [**First Name (STitle) **] (Transplant +Surgery). She will be sent home with low-dose Morphine IR and +Tylenol PRN pain. If L groin pain should become uncontrollable +on current meds, pt should return to the ED for re-evaluation. +It is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#ESRD: Renal following, continuing HD Th/Th/Sat. CaCO3 was +started for elevated calcium-phosphate product. Pt will +follow-up with Dr. [**Last Name (STitle) 7473**] in the next 1-2 weeks. + +# Anemia: Pt's baseline is 26. This is likely secondary to AOCD +and renal failure. Hct was stable on day of discharge at 25.9. + +# SVC thrombus: Pt has a history of an SVC thrombus, and is on +coumadin. She is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but INR subtherapeutic on arrival. +Heparin drip was stopped on the floor once the INR was +theraputic. INR was therapeutic on day of discharge. Pt will +need an INR check in the next week at her follow-up with her +PCP. + +# HOCM: Pt has evidence of myocardial hypertrophy on Echo. She +is currently not symptomatic. Echo did not show evidence of +worsening pericardial effusion. She was continued on her +beta-blocker and other BP medications. + +# Depression/anxiety: Stable. She was continued on Celexa and +Clonazepam. + +# OSA: Pt as continued on CPAP for sleep with 7 pressure. + +# FEN: regular diet + +# PPX: heparin drip --> coumadin, bowel regimen + +# ACCESS: PIV x2 / permanent dialysis cath L fem + +# CODE: FULL + +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +# DISPO: home with PCP and Renal [**Name9 (PRE) 702**] to re-check BP, INR +level. Follow-up with Transplant Surgery. + +Medications on Admission: +Clonidine 0.3mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 800mg PO TID +Hydromorphone 4mg PO q4H PRN +Nifedipine ER 90mg PO qday +Prednisone 4mg PO qday +Lorazepam 0.5mg PO qHS +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily +Aliskiren 150 [**Hospital1 **] + + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO Once Daily at 4 +PM. +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Nicardipine 30 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +11. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for pain for 2 weeks. +[**Hospital1 **]:*20 Tablet(s)* Refills:*0* +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours. +13. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QWED (every Wednesday). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: Hypertensive Urgency +End Stage Renal Disease + + +Discharge Condition: +stable, blood pressure moderately controlled, afebrile, +tolerating POs + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. Some of +medications were increased as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to take the coumadin as prescribed by your doctor, and have +your INR checked frequently per your PCP's recommendations. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep all +scheduled appointments. + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD (Renal) Phone:[**Telephone/Fax (1) 435**] +Date/Time:[**2142-1-15**] 3:00 +- Will follow-up Vitamin D [**2-4**] level + +Provider: [**First Name11 (Name Pattern1) 9604**] [**Last Name (NamePattern4) 43504**], MD ([**Company 191**]) Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-1-16**] 3:30 +- Will re-check your INR level + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD (Transplant Surgery) +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2142-1-19**] 2:50p + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-1-12**]",159,2142-01-08 06:36:00,2142-01-13 21:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE URGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. patient was initially observed in the micu +and placed on a nicardipine drip. patient was stablized on home +medicaitons, suggesting medication non-compliance. additionally, +patient presented subtheraputic on coumadin for svc thrombosis. +patient was started on heparin ggt. after the nicardipine drip +was turned off, patient was called out to the floor. heparin +drip was continued until inr [**2-13**]. pressures were managed to her +baseline. pain medications were decreased as patient has hypoxia +and altered mental status from over sedation, which was reversed +with narcan. patient received dialysis 3x/wk as per outpatient +schedule. + +# hypertension: pt with extensive history of repeated admissions +for hypertension. patients bp improved with nicardipine drip +and after hd off drip on home po medication regimen. resumed +oral antihypertensives with improved bp control. htn likely from +renal disease, possible medication noncompliance, lupus. no +evidence of mi. continued nifedipine, aliskerin labetalol, +hydralazine, and clonidine at current doses. renal increased +clonidine patch, and added nicardipine with improvement of bp +control. pt is to follow up with an appointment in the next week +to establish care at [**company 191**], and to re-check her bp and adjust +medications further. + +# sle: stable, continued prednisone at 4 mg po daily. + +# left groin pain. permanent hd line was placed on [**12-25**]. line +and hematoma from prior peritoneal line on abdomen okay. no +leukocytosis or fevers to suggest infection. patient was +oversedated on dilaudid and had episode of oxygen desaturation +which was reversed with narcan. patient was solmolent with +morphine sr so that was d/ced as well, patient was given +standing tylenlol and morphine ir prn. transplant surgery +removed remaining sutures today from l groin. pt has a follow-up +appointment in the next week with dr. [**first name (stitle) **] (transplant +surgery). she will be sent home with low-dose morphine ir and +tylenol prn pain. if l groin pain should become uncontrollable +on current meds, pt should return to the ed for re-evaluation. +it is anticipated that pain should resolve, as line placement +occured over 2 weeks ago. + +#esrd: renal following, continuing hd th/th/sat. caco3 was +started for elevated calcium-phosphate product. pt will +follow-up with dr. [**last name (stitle) 7473**] in the next 1-2 weeks. + +# anemia: pts baseline is 26. this is likely secondary to aocd +and renal failure. hct was stable on day of discharge at 25.9. + +# svc thrombus: pt has a history of an svc thrombus, and is on +coumadin. she is supposed to be on lifelong anticoagulation due +to recurrent thrombosis but inr subtherapeutic on arrival. +heparin drip was stopped on the floor once the inr was +theraputic. inr was therapeutic on day of discharge. pt will +need an inr check in the next week at her follow-up with her +pcp. + +# hocm: pt has evidence of myocardial hypertrophy on echo. she +is currently not symptomatic. echo did not show evidence of +worsening pericardial effusion. she was continued on her +beta-blocker and other bp medications. + +# depression/anxiety: stable. she was continued on celexa and +clonazepam. + +# osa: pt as continued on cpap for sleep with 7 pressure. + +# fen: regular diet + +# ppx: heparin drip --> coumadin, bowel regimen + +# access: piv x2 / permanent dialysis cath l fem + +# code: full + +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + +# dispo: home with pcp and renal [**name9 (pre) 702**] to re-check bp, inr +level. follow-up with transplant surgery. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Systemic lupus erythematosus; Hypoxemia; Other opiates and related narcotics causing adverse effects in therapeutic use; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Abdominal pain, other specified site; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Renal dialysis status; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Other postprocedural status]" +109,136572.0,14860,2142-06-20,14804,124657.0,2142-01-20,Discharge summary,"Admission Date: [**2142-1-14**] Discharge Date: [**2142-1-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 4028**] +Chief Complaint: +headache + +Major Surgical or Invasive Procedure: +HD + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with mild headache, mild shortness of breath and +consistent abdominal pain at the site of her known left +abdominal wall hematoma in the setting of hypertension. Her +last HD was yesterday. +. +Upon arrival to the ED, her vitals were BP 240's systolic, HR +90's, 93% on RA. A head CT scan was done which showed no acute +process. An abdominal CT was done given her femoral line pain, +which also was normal. She was given nitropaste X2 initially, +then switched to labetalol 100mg x2, then 200mg x2, then finally +started on nicardipine drip when she showed benefit with a +decrease in her BP to 170/123 and improvement in her headache. +. +Upon arrival to the MICU, patient denies any current symptoms. +She reports that her headache, shortness of breath and abdominal +pain all resolved with blood pressure management and pain +medications. +. +Pt was transferred to the floor when blood pressure was +controlled. + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +VS: HR 96 BP 171/111 RR 12 O2 98% on RA +Physical Exam: +General in NAD +HEENT NC, AT, EOMI, PERRLA, MMM +CVS RRR, 3/6 systolic murmur in all heart fields +RESP CTA BL, no crackles or wheezes +ABD soft, hematoma raised on left anterior abdominal wall, +BS, +mildly tender over hematoma +EXT left sided femoral HD line in place, no erythema, no edema +NEURO A+Ox3, CN2-12 intact, pt has left sided artificial eye, +motor and sensory intact + + + + + +Pertinent Results: +***LABS ON ADMISSION*** +[**2142-1-13**] 07:03AM WBC-5.2 RBC-2.79* HGB-8.5* HCT-26.3* MCV-94 +MCH-30.3 MCHC-32.2 RDW-19.2* +[**2142-1-13**] 07:03AM PLT COUNT-154 +[**2142-1-13**] 07:03AM PT-29.5* PTT-49.2* INR(PT)-3.0* +[**2142-1-13**] 07:03AM GLUCOSE-94 UREA N-53* CREAT-7.0* SODIUM-136 +POTASSIUM-5.1 CHLORIDE-102 TOTAL CO2-23 ANION GAP-16 +[**2142-1-13**] 07:03AM CALCIUM-8.8 PHOSPHATE-5.0* MAGNESIUM-1.9 +[**2142-1-14**] 12:00PM PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-14**] 12:00PM LIPASE-42 +[**2142-1-14**] 12:00PM ALT(SGPT)-12 AST(SGOT)-43* ALK PHOS-96 TOT +BILI-0.4 +[**2142-1-14**] 03:25PM URINE BLOOD-TR NITRITE-NEG PROTEIN-30 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-1-14**] 03:25PM URINE RBC-[**3-15**]* WBC-0-2 BACTERIA-OCC YEAST-NONE +EPI-[**3-15**] +[**2142-1-14**] 12:00PM BLOOD PT-43.8* PTT-56.1* INR(PT)-4.9* +[**2142-1-19**] 06:40AM BLOOD PT-18.6* PTT-38.7* INR(PT)-1.7* +. +***LABS ON DAY OF DISCHARGE*** + +[**2142-1-20**] 06:35AM BLOOD WBC-5.7 RBC-2.39* Hgb-7.1* Hct-22.1* +MCV-93 MCH-29.8 MCHC-32.2 RDW-18.6* Plt Ct-136* +[**2142-1-20**] 06:35AM BLOOD Glucose-107* UreaN-34* Creat-4.8* Na-137 +K-5.2* Cl-101 HCO3-27 AnGap-14 +[**2142-1-20**] 06:35AM BLOOD PT-22.8* PTT-42.3* INR(PT)-2.2* +. +IMAGING +[**2142-1-14**] EKG +Sinus rhythm. Possible left atrial abnormality. Borderline +voltage criteria +for left ventricular hypertrophy. Inferolateral ST-T wave +changes may be +related to left ventricular hypertrophy. Compared to the +previous tracing +of [**2142-1-8**] there is no significant diagnostic change. + Intervals Axes +Rate PR QRS QT/QTc P QRS T +99 190 86 368/436 13 100 24 + +[**2142-1-14**] CT ABD/PELV +IMPRESSION: +1. Interval decrease in size to subcutaneous anterior abdominal +wall +hematoma. +2. Infectious versus inflammatory process within the right lower +lobe of the +lung. Small right simple pleural effusion. +3. Cardiomegaly with slight decrease in size of moderate +pericardial +effusion. +4. Right lobe liver hemangioma, unchanged. + +[**2142-1-14**] CT HEAD +IMPRESSION: +1. Mildly limited study given administration of small amount of +IV contrast +material. However, no evidence of hemorrhage or mass effect. +NOTE ADDED AT ATTENDING REVIEW: This patient was administered +contrast for the +abdominal CT, and the head CT was performed after part of this +dose. +Therefore, this is neither a noncontrast examination, nor a +proper contrast +CT. + +[**2142-1-14**] CXR +CONCLUSION: +Persistent cardiomegaly and mild pulmonary edema. + + + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency. +. +# Hypertensive Urgency: Pt with extensive history of +hypertension. Patient's BP improved with nicardipine drip. +Became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +Restarted all home oral antihypertensives including nicardipine +30 Q8H, aliskerin 150mg [**Hospital1 **], labetalol 900mg TID, hydralazine +100mg TID, and clonidine 0.3mg + 0.1mg weekly at current doses. +Blood pressure remains labile and renal continues to follow +patient. + Pt was transferred to the floor as blood pressure stabilized. +BP has remained stable with systolics 140s-170s. In the MICU, +Nifedipine extended release was added in place of Nicardipine as +pt's blood pressures seemed to rise prior to Nicardipine doses. +. +# Hyperkalemia: Ocurred on the day after admission. Resolved +with administration of kayexalate. Pt continued hemodialysis on +TuThSat. +. +# Left abdominal wall hematoma: Abd CT showed a mild decrease +in the size. Pt reported that morphine did not help pain, and +was switched to dilaudid PO in the MICU. However, given pt's +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/c'ed on the floor. Pt was continued on +gabapentin, tylenol around the clock, and low-dose Morphine as +needed for pain. Narcotics should be avoided in the future. Pain +should also resolve in the next few weeks as hematoma resolves. +. +# SLE: Pt was continued on prednisone at 4 mg PO daily. +. +#ESRD: Renal was following during her stay. She continued HD on +her T, Th, Sat schedule. + +# Anemia: Hct was mildly decreased from baseline during +admission. This is likely secondary to AOCD and in the setting +of renal failure. +. +# SVC thrombus: Patient is on anticoagulation, likely lifelong. +Patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. Then INR became subtherapeutic, +so heparin gtt was used to bridge. On day of discharge, INR +became therapeutic, and pt was discharged home on Coumadin 4mg +PO daily, with INR to be checked next at hemodialysis +. +# HOCM: Pt has evidence of myocardial hypertrophy on recent +Echo. She was not symptomatic during her stay. She was continued +on her beta blocker. +. +# Depression/anxiety. She was continued on celexa and clonazepam +PRN. +. +# OSA: CPAP for sleep with 7 pressure. +. +# FEN: repleted lytes prn / regular diet +. +# PPX: coumadin, bowel regimen +. +# ACCESS: PIV/ permanent dialysis cath L fem +. +# CODE: FULL +. +# CONTACT: [**First Name8 (NamePattern2) **] [**Name (NI) **] (mother) [**Telephone/Fax (1) 43503**] + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nicardipine 30mg PO TID +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Morphine 15 mg Tablet Sig: 0.5 Tablet PO every eight (8) +hours as needed for breakthrough pain for 2 weeks. +2. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed for anxiety. +9. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +10. Warfarin 1 mg Tablet Sig: Four (4) Tablet PO once a day. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for pain. +12. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*1* +13. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*260 Tablet(s)* Refills:*1* +14. Respiratory Therapy +Please adjust settings of CPAP machine to a lower volume as it +is uncomfortable for the patient. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency + + +Discharge Condition: +Good, hemodynamically stable, afebrile, pain controlled + + +Discharge Instructions: +You were admitted for headaches and very high blood pressures. +You were started on an IV medication for your blood pressure +which controlled it. You were then started back on your home +medications with improvement of your blood pressure. One new +medication was added as your hypertension was difficult to +control. + +You were also started on a heparin drip while restarting your +coumadin since you have a known clot in your veins. You will +need to continue your Coumadin at 4mg daily and have your INR +checked AT DIALYSIS next week. + +Please take all medications as prescribed. It is important that +you do not miss doses of your medications since your blood +pressure is very sensitive to missed doses. Please keep ALL +scheduled appointments. +Medications changes include: +1. STOP NICARDIPINE +2. Start Nifedipine CR 90mg by mouth daily +3. INCREASE Labetalol to 900mg by mouth 3 times daily +4. Continue at Warfarin 4mg by mouth daily + +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + +Followup Instructions: +Please call your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] at [**Telephone/Fax (1) 250**] to set up +a follow-up appointment in 1-2weeks. + +Please continue your HD TuThSat. + + + +Completed by:[**2142-1-20**]",151,2142-01-14 17:34:00,2142-01-20 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency. +. +# hypertensive urgency: pt with extensive history of +hypertension. patients bp improved with nicardipine drip. +became increased yesterday when the patient missed a dose of +oral nicardipine, but came down after a replacement dose. +restarted all home oral antihypertensives including nicardipine +30 q8h, aliskerin 150mg [**hospital1 **], labetalol 900mg tid, hydralazine +100mg tid, and clonidine 0.3mg + 0.1mg weekly at current doses. +blood pressure remains labile and renal continues to follow +patient. + pt was transferred to the floor as blood pressure stabilized. +bp has remained stable with systolics 140s-170s. in the micu, +nifedipine extended release was added in place of nicardipine as +pts blood pressures seemed to rise prior to nicardipine doses. +. +# hyperkalemia: ocurred on the day after admission. resolved +with administration of kayexalate. pt continued hemodialysis on +tuthsat. +. +# left abdominal wall hematoma: abd ct showed a mild decrease +in the size. pt reported that morphine did not help pain, and +was switched to dilaudid po in the micu. however, given pts +recent prior admission required narcan following sensitivity to +narcotics, dilaudid was d/ced on the floor. pt was continued on +gabapentin, tylenol around the clock, and low-dose morphine as +needed for pain. narcotics should be avoided in the future. pain +should also resolve in the next few weeks as hematoma resolves. +. +# sle: pt was continued on prednisone at 4 mg po daily. +. +#esrd: renal was following during her stay. she continued hd on +her t, th, sat schedule. + +# anemia: hct was mildly decreased from baseline during +admission. this is likely secondary to aocd and in the setting +of renal failure. +. +# svc thrombus: patient is on anticoagulation, likely lifelong. +patient was supratherapeutic on coumadin on admission and +coumadin was subsequently held. then inr became subtherapeutic, +so heparin gtt was used to bridge. on day of discharge, inr +became therapeutic, and pt was discharged home on coumadin 4mg +po daily, with inr to be checked next at hemodialysis +. +# hocm: pt has evidence of myocardial hypertrophy on recent +echo. she was not symptomatic during her stay. she was continued +on her beta blocker. +. +# depression/anxiety. she was continued on celexa and clonazepam +prn. +. +# osa: cpap for sleep with 7 pressure. +. +# fen: repleted lytes prn / regular diet +. +# ppx: coumadin, bowel regimen +. +# access: piv/ permanent dialysis cath l fem +. +# code: full +. +# contact: [**first name8 (namepattern2) **] [**name (ni) **] (mother) [**telephone/fax (1) 43503**] + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; ; Other vascular complications of medical care, not elsewhere classified; Systemic lupus erythematosus; Hyperpotassemia; Phlebitis and thrombophlebitis of upper extremities, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,136572.0,14860,2142-06-20,14805,176760.0,2142-01-23,Discharge summary,"Admission Date: [**2142-1-21**] Discharge Date: [**2142-1-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Hypertensive Urgency and fevers + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old woman with ESRD on HD, SLE, malignant +HTN admitted with hypertensive urgency, subjective fevers, and +pain. +. +Of note, she had been hospitalized [**Date range (1) 43505**] with hypertensive +urgency. Her nicardipine was changed to nifedipine in hospital +and her labetalol was increased to 900mg TID from 800mg TID.BPs +were reportedly stable in the 140's-170's on the medical floor +on nifedipine, aliskerin, labetalol, clonidine, and hydralazine +prior to discharge. Last HD was [**1-20**]. +. +She reports feeling well at time of discharge [**1-20**], however woke +this evening feeling sweaty, hot, and mildly SOB. She did not +check her temperature and denies any rigors. She had total body +aching (worst in her left wrist at site of recent IV and abdomen +at site of known hematoma). +Palpitations overnight now +resolved. No CP, SOB, cough, diarrhea, dysuria, +erythema/tenderness/drainage from HD catheter. Denies recent +joint symptoms with her lupus. No sick contacts. Says she took +her BP meds. +. +Upon arrival to the ED, her vitals were 99.9 104 254/145 16 96% +on RA. She was started on a nicardipine drip, given 1"" +nitropaste with improvement in her BP. Did spike a fever while +in the ED, currently 101F 101 173/106 Given vancomycin and zoysn +for ?pna as CXR with right sided haziness. Also received 3mg IV +dilaudid for body pains. LUE ultrasound without evidence of DVT. + + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated dialysis [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought + +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 + +PSHx: +1. Placement of multiple catheters including dialysis. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Single and lives with her mother and a brother. She graduated +from high school. The patient is on disability. The patient does +not drink alcohol or smoke, and has never used recreational +drugs. + + +Family History: +Negative for autoimmune diseases including sle, thrombophilic +disorders. Maternal grandfather with HTN, MI, stroke in 70s. + + +Physical Exam: +T 98.5 P 92 Bp 173/116 RR 16 O2 100% on RA +General Pleasant young woman appearing comfortable +HEENT Cushingoid faces, L eye prosthesis, MMM +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 ?soft systolic murmur +Abd Soft +hematoma left abdomen unchanged from prior exam +Extrem Warm full distal pulses. Left hand with slight edema ++ +tender to palpation of wrist patient unable to make fist +secondary to pain, no erythema +warmth ?purulence at site of old +PIV +Skin No peripehral stigmata of endocarditis +Lines Left groin HD catheter site without erythema, purulence, +or tenderness +Neuro Alert and awake, moving all extremities + + +Pertinent Results: +CXR [**1-21**]: +In comparison with the earlier study of this date, the diffuse +pulmonary edema has substantially decreased, possibly following +hemodialysis. Enlargement of the cardiac silhouette persists and +there is no definite pleural effusion. Suggestion of an area of +increased opacification at the right base. This could merely +represent asymmetric edema, though the possibility of a +developing consolidation cannot be unequivocally excluded. +. +LUE US [**1-21**]: +IMPRESSION: No DVT in the left upper extremity. +. +L wrist xray [**1-21**]: +There is prominent soft tissue swelling about the wrist, +relatively diffuse, but quite prominent along the dorsum of the +wrist. No fracture, dislocation, degenerative change, focal +lytic or sclerotic lesion, or erosion is identified. No soft +tissue calcification or radiopaque foreign body is identified. A +tiny (1.7 mm) linear density is seen along the dorsum of the +wrist on the oblique view is seen only on that view and is +consistent with a small film artifact. + + +Brief Hospital Course: +24 yo woman with hx of SLE, ERSD on HD, admitted with +hypertensive urgency and left wrist pain. +. +1. Hypertensive urgency: Patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. Patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. She was started on nicardipine drip and 1"" nitropaste +and admitted to the ICU for further treatment. There was no +evidence of end-organ ischemia. Upon arrival to the ICU she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. It was felt that pain and anxiety were both +contributing to her elevated BPs. Her BP quickly stabilized and +she was called out to the medical floor where her SBP ranged +110-150. She was continued on nifepidine 90mg daily, aliskerin +150mg [**Hospital1 **], labetalol 900mg TID, hydralazine 100mg TID, and +clonidine 0.3mg + 0.1mg weekly at current doses. Given her +repeated admissions with hypertensive urgency a meeting was held +between the patient's nephrologist Dr. [**Last Name (STitle) 4883**], her ICU +physician and her [**Name9 (PRE) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +ICU where she quickly improves with simply continuing her home +medications. The following plan was drafted and placed in a +note in OMR titled "" Care Protocol"". +. +CARE PROTOCOL: +. +BLOOD PRESSURE MANAGEMENT: +. +For BP > 230/140 +1. Hydralazine: 100 mg PO OR 10 mg IV q 20 minutes until blood +pressure back to baseline*. +. +2. Give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. If after one hour of therapy AND/OR evidence of end organ +damage, transfer to the ICU. +. +* Note: Her usual blood pressure is ~ 160/100. Efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. In the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +PAIN MANAGEMENT: +. +As an outpatient, Ms. [**Name13 (STitle) **] takes dilaudid 2-4 mg PO q 4 +PRN.This is being slowly tapered, she should not be administered +IV pain medications. +. +ANTICOAGULATION: +. +In the absence of bleeding, warfarin does not need to be stopped +on admission. Similarly, in the absence of new thrombosis, +subtherapeutic INR's do not require bridging with IV UFH. +. +2. Fever: Possible sources included line infection, +thombophlebitis, septic arthritis, PNA. Received vanc/zosyn in +ED for possible PNA. UA without pyuria and urine culture +negative. CXR also without convinving infiltrate on repeat +PA/Lat so zosyn was discontinued. Patient was complaining of +severe pain at her IV site and was noted to have a small abscess +there which was felt to be the cause of her fever. She was +continued on IV vanco with HD for 10day course. She remained +afebrile and did not have a leukocytosis. +. +3. Left wrist pain: Began following IV placement during recent +hospitalization. Likely due to septic thrombophlebitis. Small +abscess was too small to drain. This was treated with warm +soaks and prn PO dilaudid. Vanco was continued for 10 day +course. L wrist films were enremarkable. +. +4. Left abdominal wall hematoma: Stable on exam from recent +admission. She was continued on pain management with morphine +7.5mg TID, gabapentin and tylenol as needed for pain. +. +5. SLE: Continued prednisone at 4 mg PO daily +. +6. ESRD: Continued on regularly scheduled dialysis. +. +7. Anemia: Baseline Hct 26. Her Hct was mildly decreased from +baseline. Secondary to AOCD and renal failure. There was no +evidence of bleeding. +. +8. SVC thrombus: Known SVC thrombus, therapeutic on coumadin. +Continued warfarin. +. +9. HOCM: evidence of myocardial hypertrophy on recent Echo. +Currently not symptomatic. Echo without evidence of worsening +pericardial effusion. Continued beta blocker +. +10. Depression/anxiety. Continued Celexa, clonazepam 0.5mg [**Hospital1 **] +. +11. OSA: Continued CPAP + + +Medications on Admission: +Clonidine 0.3mg + 0.1mg / 24 hr patch weekly qwednesday +Hydralazine 100mg PO q8H +Labetalol 900mg PO TID +Morphine 7.5mg Q8H PRN +Nifedipine 90mg PO daily +Aliskiren 150 [**Hospital1 **] +Prednisone 4mg PO qday +Clonazepam 0.5 mg [**Hospital1 **] +Celexa 20mg PO qday +Gabapentin 300 mg [**Hospital1 **] +Acetaminophen 325-650 mg q6H PRN +Ergocalciferol (Vitamin D2) 50,000 unit PO once a month +Coumadin 4 mg daily + +Discharge Medications: +1. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +[**Hospital1 **]:*90 Tablet(s)* Refills:*2* +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +[**Hospital1 **]:*4 Patch Weekly(s)* Refills:*2* +4. Labetalol 300 mg Tablet Sig: Three (3) Tablet PO three times +a day. +[**Hospital1 **]:*270 Tablet(s)* Refills:*2* +5. Morphine 15 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 hours) +as needed for pain. +[**Hospital1 **]:*15 Tablet(s)* Refills:*0* +6. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Hospital1 **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +11. Warfarin 4 mg Tablet Sig: One (1) Tablet PO once a day. +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Hospital1 **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +13. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO once a month. +14. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 7 days. +[**Hospital1 **]:*4 dose* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive urgency +Septic thrombophlebitis + + +Discharge Condition: +Stable, afebrile, BP improved. + + +Discharge Instructions: +You were admitted to the hospital with hypertensive urgency. +You required IV medications and were observed overnight in the +ICU. Your usual oral blood pressure medications were continued +and your blood pressure remained well-controlled. + +You were found to have an infection at your prior IV site on +your left hand. For this you were given IV vancomycin. You +will need 7 days more of antibiotics which will be given with +dialysis. + +Please resume your usual dialysis schedule. Your last dialysis +was [**1-23**]. + +Please continue to take your medications as prescribed. You +should hold your coumadin today. You can resume this on +wednesday at your normal dose. You should have your INR checked +at dialyis as usual on thursday. +. +If you develop any of the following concerning symptoms, please +call your PCP or go to the ED: fevers, chills, chest pains, +shortness of breath, nausea, vomiting, or headaches. + + +Followup Instructions: +Please follow up with your PCP [**Last Name (NamePattern4) **] [**1-12**] weeks. + + + +",148,2142-01-21 11:23:00,2142-01-23 16:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSIVE EMERGENCY," +24 yo woman with hx of sle, ersd on hd, admitted with +hypertensive urgency and left wrist pain. +. +1. hypertensive urgency: patient has an history of malignant +hypertension, with multiple recurrent admissions for +hypertensive urgency. patient represented the evening after her +discharge from the hospital and was found to be hypertensive to +254/145. she was started on nicardipine drip and 1"" nitropaste +and admitted to the icu for further treatment. there was no +evidence of end-organ ischemia. upon arrival to the icu she was +given her usual home antihypertensives and the nicardipine was +quickly weaned off. it was felt that pain and anxiety were both +contributing to her elevated bps. her bp quickly stabilized and +she was called out to the medical floor where her sbp ranged +110-150. she was continued on nifepidine 90mg daily, aliskerin +150mg [**hospital1 **], labetalol 900mg tid, hydralazine 100mg tid, and +clonidine 0.3mg + 0.1mg weekly at current doses. given her +repeated admissions with hypertensive urgency a meeting was held +between the patients nephrologist dr. [**last name (stitle) 4883**], her icu +physician and her [**name9 (pre) **] to come up with a plan for +treatment in order to try and avoid repeated admissions to the +icu where she quickly improves with simply continuing her home +medications. the following plan was drafted and placed in a +note in omr titled "" care protocol"". +. +care protocol: +. +blood pressure management: +. +for bp > 230/140 +1. hydralazine: 100 mg po or 10 mg iv q 20 minutes until blood +pressure back to baseline*. +. +2. give daily blood pressure medications, if she has not already +taken them before arrival. +. +3. if after one hour of therapy and/or evidence of end organ +damage, transfer to the icu. +. +* note: her usual blood pressure is ~ 160/100. efforts should +not be made to lower blood pressure further, as this may +precipitate end organ hypoperfusion. in the absence of clear +end-organ damage, parenteral blood pressure medications (other +than +hydralazine) are generally not required. +. +pain management: +. +as an outpatient, ms. [**name13 (stitle) **] takes dilaudid 2-4 mg po q 4 +prn.this is being slowly tapered, she should not be administered +iv pain medications. +. +anticoagulation: +. +in the absence of bleeding, warfarin does not need to be stopped +on admission. similarly, in the absence of new thrombosis, +subtherapeutic inrs do not require bridging with iv ufh. +. +2. fever: possible sources included line infection, +thombophlebitis, septic arthritis, pna. received vanc/zosyn in +ed for possible pna. ua without pyuria and urine culture +negative. cxr also without convinving infiltrate on repeat +pa/lat so zosyn was discontinued. patient was complaining of +severe pain at her iv site and was noted to have a small abscess +there which was felt to be the cause of her fever. she was +continued on iv vanco with hd for 10day course. she remained +afebrile and did not have a leukocytosis. +. +3. left wrist pain: began following iv placement during recent +hospitalization. likely due to septic thrombophlebitis. small +abscess was too small to drain. this was treated with warm +soaks and prn po dilaudid. vanco was continued for 10 day +course. l wrist films were enremarkable. +. +4. left abdominal wall hematoma: stable on exam from recent +admission. she was continued on pain management with morphine +7.5mg tid, gabapentin and tylenol as needed for pain. +. +5. sle: continued prednisone at 4 mg po daily +. +6. esrd: continued on regularly scheduled dialysis. +. +7. anemia: baseline hct 26. her hct was mildly decreased from +baseline. secondary to aocd and renal failure. there was no +evidence of bleeding. +. +8. svc thrombus: known svc thrombus, therapeutic on coumadin. +continued warfarin. +. +9. hocm: evidence of myocardial hypertrophy on recent echo. +currently not symptomatic. echo without evidence of worsening +pericardial effusion. continued beta blocker +. +10. depression/anxiety. continued celexa, clonazepam 0.5mg [**hospital1 **] +. +11. osa: continued cpap + + + ","PRIMARY: [Other vascular complications of medical care, not elsewhere classified] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; ; Systemic lupus erythematosus; Phlebitis and thrombophlebitis of upper extremities, unspecified]" +109,189332.0,14865,2142-08-30,14808,158943.0,2142-03-23,Discharge summary,"Admission Date: [**2142-3-21**] Discharge Date: [**2142-3-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +Abdominal Pain, Shortness of breath, Chest discomfort + +Major Surgical or Invasive Procedure: +HD [**2142-3-21**] and [**2142-3-23**] + + +History of Present Illness: +The pt is a 24 y.o. F with ESRD on HD, SLE, malignant HTN, +history of SVC syndrome, PRES, recently discharged on [**2142-3-18**] +after admission for abdominal pain, MSSA bacteremia, paroxysmal +hypertension and ESRD line, presents with central crampy +abdominal pain, chest discomfort, SOB, HTN to 230s. Pt states +that at around 11pm last night developed shortness of breath +that felt as though someone was sitting on her chest. She states +that she feels as though she cannot catch her breath. Pt also +describes chest discomfort which she states that she has not had +before. She also has her chronic abdominal pain. She states that +it comes and goes and is unchanged from her baseline. +. +In the ED, initial vitals: 98.9 [**Telephone/Fax (3) 43508**]4 100%RA. SBP as +high as 241 recorded. She received Labetalol 20 IV x 2 without +improvement. She was given hydral 20 IV without improvement, so +she was placed on a Labetalol gtt @ 4 mg/min with improvement of +SBP 220. She was given IV Zofran, IV dilaudid, Hydralazine 50mg +po, Labetolol 200mg po, Labetolol 100mg IV x 3, Levofloxacin +750mg IV, Ceftriaxone 1g IV, Vancomycin 1g IV, weregiven for +question of infiltrate on CXR prior to CT. Nitroprusside gtt +added and .5 mg/kg, pressure initially improved to 180s. Tried +to wean off the nitroprusside and pressure went back up to 208. +Chest pain has resolved, still SOB with abdominal pain. Pan-scan +w/o contrast showed interval worsening of chronic pulmonary +edema. Pleural and pericardial effusions stable. Ativan seemed +to help symptoms. + +One blood culture was sent in the ED. Per report, EKG showed +LVH, ST depression in V6. Trop a little more elevated than +normal but CKs flat. [**Telephone/Fax (3) **] was discussed with renal and it +was not felt that HTN is a volume issue so no need for emergent +[**Telephone/Fax (3) 2286**]. +. +Upon arrival to the floor, her SBP was 203. She continued to +complain of abdominal pain and shortness of breath though her +chest discomfort was improved. Respiratory rate up to 30. + + +Past Medical History: +1. Systemic lupus erythematosus: +- Diagnosed [**2134**] (16 years old) when she had swollen fingers, +arm rash and arthralgias +- Previous treatment with cytoxan, cellcept; currently on +prednisone +- Complicated by uveitis ([**2139**]) and ESRD ([**2135**]) +2. CKD/ESRD: +- Diagosed [**2135**] +- Initiated [**Year (4 digits) 2286**] [**2137**] but refused it as of [**2140**], has +survived despite this +- PD catheter placement [**5-18**] +3. Malignant hypertension +- Baseline BPs 180's - 120's +- History of hypertensive crisis with seizures +- History of two intraparenchymal hemorrhages that were thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] that resolved +4. Thrombocytopenia: +- TTP (got plasmapheresisis) versus malignant HTN +5. Thrombotic events: +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy: may be etiology of episodes of +worse hypertension given appears quite labile +12. Obstructive sleep apnea, AutoCPAP/ Pressure setting [**5-20**], +Straight CPAP/ Pressure setting 7 +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**], getting Vanc with HD. +. +PSHx: +1. Placement of multiple catheters including [**Year (4 digits) 2286**]. +2. Tonsillectomy. +3. Left eye enucleation in [**2140-4-10**]. +4. PD catheter placement in [**2141-5-11**]. +5. S/P Ex-lap for free air in abdomen, ex-lap normal [**2141-10-27**] + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +PE: 98.6 128/98 82 20 100% on 2L NC +vitals +Gen- NAD +HEENT- MMM +CV- Regular, nl S1, s2, + s3. +Lungs- CTA bilat +Abd- + BS, soft, ND. Tender only to deep palpation +Ext- 2+ DP bilat. trace pedal edema +Neuro- AA+Ox3. + + +Pertinent Results: +Admission Labs: + +[**2142-3-21**] 02:20AM WBC-5.0 RBC-2.61* HGB-7.7* HCT-23.5* MCV-90 +MCH-29.4 MCHC-32.6 RDW-19.3* +[**2142-3-21**] 02:20AM NEUTS-76.1* BANDS-0 LYMPHS-17.9* MONOS-4.5 +EOS-1.1 BASOS-0.5 +[**2142-3-21**] 02:20AM PLT SMR-NORMAL PLT COUNT-168 +[**2142-3-21**] 02:20AM PT-21.8* PTT-34.7 INR(PT)-2.1* +[**2142-3-21**] 02:20AM cTropnT-0.12* +[**2142-3-21**] 02:20AM ALT(SGPT)-46* AST(SGOT)-94* CK(CPK)-76 ALK +PHOS-173* TOT BILI-0.4 +[**2142-3-21**] 02:20AM GLUCOSE-74 UREA N-47* CREAT-7.3* SODIUM-140 +POTASSIUM-5.8* CHLORIDE-109* TOTAL CO2-19* ANION GAP-18 +[**2142-3-21**] 04:00AM URINE BLOOD-TR NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-21**] 08:00AM URINE BLOOD-SM NITRITE-NEG PROTEIN-500 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-7.0 +LEUK-NEG +[**2142-3-21**] 12:58PM CK-MB-NotDone cTropnT-0.12* +. +CT C/A/P - [**2142-3-20**] - +1. Interval worsening of pulmonary edema, now moderate to +severe. Unchanged moderate pericardial effusion. Periportal +edema persists. + +2. Small right pleural effusion, unchanged. + +3. Small amount of ascites. + +4. No evidence of bowel obstruction. Contrast material reaches +the rectum. + +5. Redemonstration of extensive mediastinal and hilar +lymphadenopathy. + +The study and the report were reviewed by the staff radiologist. + + +Discharge labs: + +[**2142-3-23**] 12:00PM BLOOD WBC-3.7* RBC-2.87* Hgb-8.7* Hct-26.1* +MCV-91 MCH-30.3 MCHC-33.3 RDW-19.4* Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD Plt Ct-130* +[**2142-3-23**] 12:00PM BLOOD PT-28.8* PTT-58.6* INR(PT)-2.9* +[**2142-3-23**] 12:00PM BLOOD Glucose-77 UreaN-31* Creat-6.0*# Na-137 +K-4.8 Cl-104 HCO3-24 AnGap-14 +[**2142-3-23**] 12:00PM BLOOD Calcium-8.4 Phos-5.7* Mg-1.9 + +Brief Hospital Course: +This is a 24 y.o F with SLE, ESRD on HD and malignant +hypertension + presenting with abd pain, diarrhea, and HTN. +. +# Hypertension: The patient had very high blood pressures on +presentation (200's/100's) that nevertheless are within levels +she's certainly reached during previous admissions. Initial +attempts were made to control her BP with hydralazine and +labetalol IV but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the ICU. This was then changed to a nicardipine +drip. She was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. The next day, her BP +remained within goal of 120's/80's. She was dialyzed and sent +home. +. +Tachypnea/Shortness of breath - On admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. Has OSA. CE's were cycled and were +negative. CPAP was continued as tolerated at home settings. SOB +resolved after HD on [**2142-3-21**] +. +# abdominal pain: Consistent with patient's baseline chronic +abdominal pain. Medication effect also possible. CT prelim neg +for small bowel obstruction. LFTs doubled from [**2142-3-18**]. On +arrival to the floor, abd pain was back to baseline and well +controlled on Dilaudid 2mg PO q 4hrs +. +# ESRD: Renal followed. HD given [**3-21**] and [**3-23**] +. +# Coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. Continued coumadin +. +# HOCM: evidence of myocardial hypertrophy on Echo. Currently +not symptomatic. Continued labetalol. + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. +14. Vancomycin at HD + + +Discharge Medications: +1. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at 4 +PM. +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid () as +needed for Severe HTN. +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Month/Year (2) **]:*30 Tablet(s)* Refills:*2* +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO Q8H (every 8 hours) as needed. +10. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +11. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). + + +Discharge Disposition: +Home + +Discharge Diagnosis: +SLE +ESRD on HD +Malignant hypertension +Chronic abdominal pain + + +Discharge Condition: +Good. Tolerating POs. BP 110's/80's + + +Discharge Instructions: +You were admitted with hypertension and abdominal pain. While +you were here, we treated your hypertension with medications and +dialyzed you. Your hypertension is resolved at the time of +discharge. Your belly pain partially resolved and at time of +discharge is comparable to your chronic belly pain. +. +Please follow up as below. +. +Please continue your medications as prescribed. +. +Please call your doctor or return to the ED if you have any +headaches, lightheadedness, changes in vision, vomitting, blood +in your stool, loss of consciousness or any other concerning +symptoms. + +Followup Instructions: +Please follow up with your primary care doctor within 1 week. +You need to schedule an appointment with either your PCP or +OB/GYN for a pap smear as soon as possible. You should also get +a repeat urinalysis and urine culture if you have any UTI +symptoms. +. +Please continue [**Month/Year (2) 2286**] sessions as directed by the nephrology +team- your next session should be on Tuesday. + + + +Completed by:[**2142-3-26**]",160,2142-03-21 09:25:00,2142-03-23 18:11:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CHEST PAIN;TELEMETRY," +this is a 24 y.o f with sle, esrd on hd and malignant +hypertension + presenting with abd pain, diarrhea, and htn. +. +# hypertension: the patient had very high blood pressures on +presentation (200s/100s) that nevertheless are within levels +shes certainly reached during previous admissions. initial +attempts were made to control her bp with hydralazine and +labetalol iv but after these failed to control her blood +pressure, she was started on a labetalol and nitroprusside drip +and admitted to the icu. this was then changed to a nicardipine +drip. she was successfully transitioned to home medications of +clonidine, labetalol, aliskiren, nifedipine and hydralazine on +[**3-22**] and transferred to the medicine floor. the next day, her bp +remained within goal of 120s/80s. she was dialyzed and sent +home. +. +tachypnea/shortness of breath - on admission, likely due to +pulmonary edema, however, cannot rule out cardiac etiology in +setting of small enzyme leak. has osa. ces were cycled and were +negative. cpap was continued as tolerated at home settings. sob +resolved after hd on [**2142-3-21**] +. +# abdominal pain: consistent with patients baseline chronic +abdominal pain. medication effect also possible. ct prelim neg +for small bowel obstruction. lfts doubled from [**2142-3-18**]. on +arrival to the floor, abd pain was back to baseline and well +controlled on dilaudid 2mg po q 4hrs +. +# esrd: renal followed. hd given [**3-21**] and [**3-23**] +. +# coagulopathy: patient on lifetime anticoagulation for hx of +multiple thrombotic events. continued coumadin +. +# hocm: evidence of myocardial hypertrophy on echo. currently +not symptomatic. continued labetalol. + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Compression of vein; Unspecified disease of pericardium; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Primary hypercoagulable state; Other primary cardiomyopathies; ; Abdominal pain, unspecified site; Urinary tract infection, site not specified; Acidosis; Other chest pain; Other chronic pain; Systemic lupus erythematosus; Noncompliance with renal dialysis; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Hyperpotassemia; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Kidney dialysis as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Methicillin resistant Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Obstructive sleep apnea (adult)(pediatric); Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,189332.0,14865,2142-08-30,14809,124398.0,2142-03-31,Discharge summary,"Admission Date: [**2142-3-24**] Discharge Date: [**2142-3-31**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet + +Attending:[**First Name3 (LF) 2167**] +Chief Complaint: +HTN, abdominal pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +24F with ESRD on HD, SLE, malignant HTN, history of SVC +syndrome, PRES, recently discharged on [**2142-3-18**] after admission +for abdominal pain, MSSA bacteremia, paroxysmal hypertension and +ESRD line, followed by readmission [**3-22**], now presents with usual +central crampy abdominal pain, 3 loose nonbloody stools this AM, +SOB, and HTN to 270s. Pt was d/c'd from [**Hospital1 18**] yesterday after HD +session, went home, states she took her PM meds, took her 8 AM +medds (hydral, labetalol), then developed these symptoms which +precluded her from taking her usual home meds (no afternoon meds +- nifedipine, labetalol, hydral). The abd pain comes and goes +and is unchanged from her baseline. While she has nausea, she is +asking for dinner. +. +In the ED, initial BP 272/148. CXR w/o evidence of volume +overload. No CT scan performed. Started on NTG gtt, given +Hydralazine 10 x 1, Dilaudid 2 mg, labetaolo 20mg IV x 1. +. +Upon arrival to the floor, her BP was 240/135. She continued to +complain of abdominal pain but was eating crackers, breathing +felt better. RR 17. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +98.2 97 [**Telephone/Fax (2) 43509**]0% on 2 L nC +Gen: pleasant, comfortable +HEENT: L eye enucleated. moon facies. Right pupil reactive +Heart: hrrr, no m/r/g +Pulm: CTA b/l +Abd: NABS, midline scar well-healed, soft, diffuse TTP, no +rebound/guarding +Ext: no c/c/e +Neuro: aox4, cn 2-12 intact grossly. + +Pertinent Results: +[**2142-3-24**] 07:17PM PT-22.4* PTT-43.64* INR(PT)-2.1* +[**2142-3-24**] 04:45PM URINE COLOR-Yellow APPEAR-Clear SP [**Last Name (un) 155**]-1.010 +[**2142-3-24**] 04:45PM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-NEG BILIRUBIN-NEG UROBILNGN-NEG PH-8.0 +LEUK-NEG +[**2142-3-24**] 04:45PM URINE RBC-0-2 WBC-0-2 BACTERIA-FEW YEAST-NONE +EPI-[**11-30**] +[**2142-3-24**] 02:05PM GLUCOSE-76 UREA N-21* CREAT-4.8*# SODIUM-139 +POTASSIUM-4.5 CHLORIDE-105 TOTAL CO2-26 ANION GAP-13 +[**2142-3-24**] 02:05PM ALT(SGPT)-78* AST(SGOT)-181* CK(CPK)-55 ALK +PHOS-192* TOT BILI-0.5 +[**2142-3-24**] 02:05PM cTropnT-0.12* +[**2142-3-24**] 02:05PM CK-MB-5 +[**2142-3-24**] 02:05PM WBC-3.6* RBC-2.90* HGB-8.9* HCT-26.6* MCV-92 +MCH-30.7 MCHC-33.4 RDW-19.8* +[**2142-3-24**] 02:05PM NEUTS-73.9* BANDS-0 LYMPHS-18.5 MONOS-3.8 +EOS-3.0 BASOS-0.8 +[**2142-3-24**] 02:05PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-2+ +MACROCYT-2+ MICROCYT-2+ POLYCHROM-OCCASIONAL +SPHEROCYT-OCCASIONAL OVALOCYT-1+ TARGET-1+ SCHISTOCY-OCCASIONAL +TEARDROP-1+ ELLIPTOCY-OCCASIONAL +[**2142-3-24**] 02:05PM PLT SMR-LOW PLT COUNT-129* +[**2142-3-23**] 12:00PM GLUCOSE-77 UREA N-31* CREAT-6.0*# SODIUM-137 +POTASSIUM-4.8 CHLORIDE-104 TOTAL CO2-24 ANION GAP-14 +[**2142-3-23**] 12:00PM estGFR-Using this +[**2142-3-23**] 12:00PM CALCIUM-8.4 PHOSPHATE-5.7* MAGNESIUM-1.9 +[**2142-3-23**] 12:00PM WBC-3.7* RBC-2.87* HGB-8.7* HCT-26.1* MCV-91 +MCH-30.3 MCHC-33.3 RDW-19.4* +[**2142-3-23**] 12:00PM PLT COUNT-130* +[**2142-3-23**] 12:00PM PT-28.8* PTT-58.6* INR(PT)-2.9* + +Brief Hospital Course: +The patient was admitted to the MICU on a NTG gtt from the ED. +Her abdominal pain had imporved and she was eating crackers and +peanut butter. She was given her usual afternoon home +medications, and transitioned to a Nicardipine gtt, which has +worked well for her in the past. Her BP goal was for a systolic +of 180-200. The Nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +On arrival to the floor, she in fact missed her morning +medications on [**Month/Day/Year 766**]. This resulted in elevate blood pressures +requiring IV hydralazing for control. She went to dialyisis +Tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**Month/Year (2) 2286**] from missing her AM doses. Instructions were +written for explicit AM administration and Nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. She was continued on +labetalol 900mg TID, Aliskerin, Hydralazine 100mg po TID, and +clonidine patch 0.4mg/24 weekly patch. +. +HEr BP remained relativly stable. She established a three three +times weekly Dialysus regemin. A PAP smear was attempted due to +her history of CIN I and no PCP follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +Her abdominal pain was also a chronic issue, which appeared +stable. She was not administered IV narcotics, only PO. It was +wihtout clear percipitating events or etiology. She will need GI +follow up. She was contact[**Name (NI) **] by phone several times to arrange +a GI follow up appointment but did not return messages. She has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +She was discharged to followup with her nephrologist, Dr. +[**Last Name (STitle) 4883**]. +. + + +Medications on Admission: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4PM. +5. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +6. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +7. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +8. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +10. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +12. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +13. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO three times a day as needed for nausea for 4 +days. + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +[**Last Name (STitle) **]:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*2* +3. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). +[**Last Name (STitle) **]:*120 Tablet(s)* Refills:*2* +4. Labetalol 200 mg Tablet Sig: 4.5 Tablets PO TID (3 times a +day). +[**Last Name (STitle) **]:*405 Tablet(s)* Refills:*2* +5. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*2* +6. Nifedipine 30 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +[**Last Name (STitle) **]:*30 Tablet Sustained Release(s)* Refills:*2* +8. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO bid (). +[**Last Name (STitle) **]:*60 Tablet(s)* Refills:*2* +9. Clonidine 0.2 mg/24 hr Patch Weekly Sig: Two (2) Patches +Transdermal once a week: Place two patches every week on +Fridays. +[**Last Name (STitle) **]:*8 Patches* Refills:*2* +10. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours. +[**Last Name (STitle) **]:*180 Tablet(s)* Refills:*0* +11. Clonidine 0.3 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for prn SBP>200: if nauseated and cannot keep down +meds, may use 1 sublingual clonidine if sbp>200. . +[**Last Name (STitle) **]:*30 Tablet(s)* Refills:*0* +12. Kayexalate Powder Sig: Thirty (30) grams PO once a day +for 2 days: please take [**2142-4-1**] and [**2142-4-2**] for elevated +potassium. +[**Month/Day/Year **]:*240 grams* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Systemic Lupus Erythematosus +End Stage Renal Disease +Hypertension +Abdominal Pain + + +Discharge Condition: +Blood pressure stable and abdominal pain at baseline + + +Discharge Instructions: +You were admitted with high blood pressure. You were in the ICU +overnight for treatment. Some of your medications were changed +and you were increased to three times weekly [**Location (un) 2286**]. Your +abdominal pain is a difficult problem, as the reason for the +pain is unclear. [**Name2 (NI) **] were continued on oral dilaudid. IV +dilaudid is strongly discouraged and will continue to be in the +future. + +You are now taking Nifedipine SR 30mg at night in addition to +90mg in the morning. Your other medications were the same. + +At home, if your blood pressure is above 200, then take 100mg +hydralazine. If after 1 hour, your blood pressure does not +decrease to below 200 with this, then take another 100mg +hydralazine. If you are nauseated and cannot take in oral meds, +then take sublingual clonidine, then wait 1 hour and repeat if +BP still > 200. + +Finally, your potassium has been high. Please take kayexalate +30gm tomorrow and the next day. + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-3-31**] +7:30 +Provider: [**Name10 (NameIs) **],[**Name11 (NameIs) **] [**Name Initial (NameIs) **]. [**Telephone/Fax (1) 250**] Call to schedule +appointment + +We will attempt to contact you on [**Name (NI) 766**] with appointment times +for you. + + + +",152,2142-03-24 16:34:00,2142-03-31 15:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +the patient was admitted to the micu on a ntg gtt from the ed. +her abdominal pain had imporved and she was eating crackers and +peanut butter. she was given her usual afternoon home +medications, and transitioned to a nicardipine gtt, which has +worked well for her in the past. her bp goal was for a systolic +of 180-200. the nicardipine gtt was titrated off quickly and she +was transfered to the floor. +. +on arrival to the floor, she in fact missed her morning +medications on [**month/day/year 766**]. this resulted in elevate blood pressures +requiring iv hydralazing for control. she went to dialyisis +tuesday [**3-27**] and again had markedly elevated blood pressures +while at [**month/year (2) 2286**] from missing her am doses. instructions were +written for explicit am administration and nifedipine long +acting 30mg was added at night, in addition to the 90mg long +acting she was taking in the morning. she was continued on +labetalol 900mg tid, aliskerin, hydralazine 100mg po tid, and +clonidine patch 0.4mg/24 weekly patch. +. +her bp remained relativly stable. she established a three three +times weekly dialysus regemin. a pap smear was attempted due to +her history of cin i and no pcp follow up, but was unsucesfull +due to a very small vaginal introutus and no small specuilum +available. +. +her abdominal pain was also a chronic issue, which appeared +stable. she was not administered iv narcotics, only po. it was +wihtout clear percipitating events or etiology. she will need gi +follow up. she was contact[**name (ni) **] by phone several times to arrange +a gi follow up appointment but did not return messages. she has +a history of multiple missed appointments and no appoitment was +made without confirming with the patient that she would attend. +. +she was discharged to followup with her nephrologist, dr. +[**last name (stitle) 4883**]. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; ; Systemic lupus erythematosus; Anemia in chronic kidney disease; Long-term (current) use of steroids; Other chronic pain; Obstructive sleep apnea (adult)(pediatric); Abdominal pain, generalized; Hyperpotassemia]" +109,189332.0,14865,2142-08-30,14810,137510.0,2142-04-22,Discharge summary,"Admission Date: [**2142-4-20**] Discharge Date: [**2142-4-22**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 1253**] +Chief Complaint: +Dyspnea, malignant hypertension + + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Briefly, 24 F with ESRD on hemodialysis, SLE, malignant +hypertension, history of SVC syndrome, PRES who presented with +abdominal pain and shortness of breath. On [**2142-4-19**] she refused +ultrafiltration at HD because she was at her dry weight. Awoke +at 3 AM feeling more short of breath. She also had worsening +abdominal pain and vomiting without hematemasis. She took all of +her medications as prescribed including two new lidocaine +patches, fentanyl patch and clonidine. She developed a slight +frontal headache but no blurry vision or neurologic symptoms. +ROS largely negative. +. +In the emergency room her initial vitals were T: 99.1 BP: +280/140 HR: 79 RR: 16 O2: 100% on RA. She had two large bore +peripheral IVs placed. She received 100 mg PO hydralazine, 200 +mg PO labetolol, zofran 4 mg IV, vancomycin 1 gram IV, +levofloxacin 750 mg IV x 1 and was started on labetolol and +nitroglycerin drips with control of her blood pressure to the +180s systolic. She had a CXR which was concerning for volume +overload. She was admitted the MICU for further evaluation. +. +In the MICU she was stablized and transitioned to her home meds. + Nephrology gave her HD with 2L UF and subjective improvement in +SOB. +. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of [**Year (4 digits) 2286**], currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +On Admission per MICU team: +Vitals: T: 96.5 BP: 162/120 HR: 79 RR: 13 O2: 100% on 4L +General: Pleasant, comfortable, no distress +HEENT: L eye enucleated. Moon facies. Right pupil reactive +Heart: Regular rate and rhythm, s1 + s2, soft systolic murmur at +RLSB, no rubs or gallops +Respiratory: Crackles at bases bilaterally, no wheezes, rales, +ronchi +GI: soft, non-tender, non-distended, +BS +GU: no foley +Ext: Warm and well perfused, no clubbing, cyanosis or edema +. + + +Pertinent Results: +[**2142-4-19**] 08:35AM WBC-3.8* RBC-2.53* HGB-7.6* HCT-23.4* MCV-93 +MCH-29.9 MCHC-32.3 RDW-19.9* +[**2142-4-19**] 08:35AM PLT COUNT-93* +. +[**2142-4-19**] 08:35AM GLUCOSE-88 UREA N-36* CREAT-6.0* SODIUM-135 +POTASSIUM-5.7* CHLORIDE-101 TOTAL CO2-25 ANION GAP-15 +[**2142-4-19**] 08:35AM CALCIUM-9.4 PHOSPHATE-5.3* MAGNESIUM-2.0 +. +[**2142-4-20**] 08:40AM PT-28.3* PTT-45.3* INR(PT)-2.9* +. +CXR PA and LAT: +IMPRESSION: +1. Persistent cardiomegaly with prominence of pulmonary +vasculature suggesting overhydration. Minimal costophrenic angle +blunting may suggest small effusions. +2. No definite consolidation, although increased retrocardiac +density is noted, most likely due to atelectasis and vascular +congestion. Repeat imaging following diuresis could be +considered. +. +INR trend: +[**2142-4-19**] 09:30AM BLOOD PT-30.4* INR(PT)-3.1* +[**2142-4-20**] 08:40AM BLOOD PT-28.3* PTT-45.3* INR(PT)-2.9* +[**2142-4-21**] 04:07AM BLOOD PT-29.9* PTT-48.9* INR(PT)-3.1* +[**2142-4-22**] 05:55AM BLOOD PT-33.3* PTT-54.1* INR(PT)-3.5* + +Brief Hospital Course: +24 F with ESRD on hemodialysis, SLE, malignant hypertension, +history of SVC syndrome, PRES who presented to the ICU for +hypertensive emergency, dyspnea, and headache, now resolved. +. +Hypertensive Emergency: Patient's blood pressure normalized with +transient nitroglycerin and labetalol drips. Likely precipitated +by lack of ultrafiltration at [**Year/Month/Day 2286**] yesterday. She has +received [**Year/Month/Day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- Nifedipine 150 mg Tablet SR daily +- Hydralazine 100 mg Tablet Q8H +- Labetalol 1000 mg Tablet TID +- Aliskiren 150 mg Tablet PO BID +- Clonidine 0.2 mg/24 hr Patch Weekly +- Hydralazine 100 mg PO PRN for SBP > 200 +- continue regular [**Year/Month/Day 2286**] schedule +. +Social Issues/repeated admissions: The ICU and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. These +episodes may be due to medication non-compliance and it may +benefit Ms. [**Known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. Ms. [**Known lastname **] [**Last Name (Titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. Of note, she has +missed [**Last Name (Titles) 2286**] sessions and often requests durations and flow +rates for her [**Last Name (Titles) 2286**] that contradict recommendations by her +nephrologist. This issue was left unresolved on discharge. +. +Chronic Abdominal Pain: Currently managed with PO dilaudid, +fentanyl patch and lidocaine patch. Per MICU team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue PO dilaudid +- continue lidocaine patch +. +Lupus Erythematous: Complicated by uveitis and ESRD. +- continued prednisone +. +ESRD: On [**Last Name (Titles) 2286**]. Ultrafiltrate of 2 L on initial HD - continue +outpatient regimen +. +Thrombocytopenia: Remained at baseline 80s to 130s. +. +Thrombotic Events: History of SVC thrombosis with negative +workup. INR drifted up and was 3.5 on discharge. She was asked +to hold her warfarin dose this PM and recheck her INR with VNA +services on [**2142-4-23**] to be faxed to coumadin clinic in [**Company 191**]. +- continued coumadin +. +Anemia: Hematocrit 24.5 initially. Baseline 23 to 28. +. + + +Medications on Admission: +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H +Prednisone 1 mg Tablet +Citalopram 20 mg Tablet +Pantoprazole 40 mg Tablet, +Warfarin 3 mg daily +Gabapentin 300 mg TID +Nifedipine 90 mg Tablet SR daily +Nifedipine 60 mg Tablet SR daily +Hydralazine 100 mg Tablet Q8H +Labetalol 1000 mg Tablet TID +Aliskiren 150 mg Tablet PO BID +Clonidine 0.2 mg/24 hr Patch Weekly +Docusate Sodium 100 mg Capsule PO BID +Senna 8.6 mg Tablet +Fentanyl 25 mcg/hr Patch 72 hr +Lidocaine 5 %(700 mg/patch) daily +Hydralazine 100 mg PO:PRN for SBP > 200 + +Discharge Medications: +1. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +2. Prednisone 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day: DO +NOT TAKE DOSE ON [**2142-4-22**]. Then restart per your PCP. +6. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +7. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +8. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +9. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +10. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +11. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +12. Clonidine 0.2 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal QSAT (every Saturday). +13. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +14. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +15. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +16. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +17. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID (2 times +a day) as needed: For systolic blood pressure > 200. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Malignant Hypertension +Systemic Lupus Erythematosus +End Stage Renal Disease +Abdominal Pain + + +Discharge Condition: +good, VSS, on room air, pain controlled. + + +Discharge Instructions: +You came to the hospital for shortness of breath and +hypertension. You were given antihypertensive drips and during +[**Location (un) 2286**] 2 liters were taken off with good improvement in your +shortness of breath. You will need to take your medications as +prescribed and follow-up with all of your doctors to prevent +coming into the hospital. +. +Medication changes: +- Please do not take your coumadin tonight because your INR is +too high. You will need to have it checked by VNA services and +adjusted. +- Please take ALL of your medications as prescribed. +. +Please call your doctor or return to the ED if you have +intractable headaches, shortness of breath, intractable pain or +other concerns. + +Followup Instructions: +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-4-26**] 3:30 +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-5-25**] 9:30 + + + +Completed by:[**2142-4-23**]",130,2142-04-20 13:39:00,2142-04-22 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PULMONARY EDEMA;HYPERTENSION," +24 f with esrd on hemodialysis, sle, malignant hypertension, +history of svc syndrome, pres who presented to the icu for +hypertensive emergency, dyspnea, and headache, now resolved. +. +hypertensive emergency: patients blood pressure normalized with +transient nitroglycerin and labetalol drips. likely precipitated +by lack of ultrafiltration at [**year/month/day 2286**] yesterday. she has +received [**year/month/day 2286**] and her blood pressures remained at her +baseline off the drips. +- continue home blood pressure regimen +- nifedipine 150 mg tablet sr daily +- hydralazine 100 mg tablet q8h +- labetalol 1000 mg tablet tid +- aliskiren 150 mg tablet po bid +- clonidine 0.2 mg/24 hr patch weekly +- hydralazine 100 mg po prn for sbp > 200 +- continue regular [**year/month/day 2286**] schedule +. +social issues/repeated admissions: the icu and medicine floor +addendings felt it important to express concern over her +repeated, frequent admissions for hypertensive urgency. these +episodes may be due to medication non-compliance and it may +benefit ms. [**known lastname **] to be evaluated by an extended care facility +to ensure proper blood pressure monitoring and health care in +general. ms. [**known lastname **] [**last name (titles) 323**] refused to go to a ""home"" and +declined to talk to social work at this time. of note, she has +missed [**last name (titles) 2286**] sessions and often requests durations and flow +rates for her [**last name (titles) 2286**] that contradict recommendations by her +nephrologist. this issue was left unresolved on discharge. +. +chronic abdominal pain: currently managed with po dilaudid, +fentanyl patch and lidocaine patch. per micu team, prior +authorization paperwork for fentanyl was sent during last +admission and is pending. +- continue fentanyl patch +- continue po dilaudid +- continue lidocaine patch +. +lupus erythematous: complicated by uveitis and esrd. +- continued prednisone +. +esrd: on [**last name (titles) 2286**]. ultrafiltrate of 2 l on initial hd - continue +outpatient regimen +. +thrombocytopenia: remained at baseline 80s to 130s. +. +thrombotic events: history of svc thrombosis with negative +workup. inr drifted up and was 3.5 on discharge. she was asked +to hold her warfarin dose this pm and recheck her inr with vna +services on [**2142-4-23**] to be faxed to coumadin clinic in [**company 191**]. +- continued coumadin +. +anemia: hematocrit 24.5 initially. baseline 23 to 28. +. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Unspecified iridocyclitis; Other primary cardiomyopathies; Unspecified disease of pericardium; ; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Noncompliance with renal dialysis; Personal history of noncompliance with medical treatment, presenting hazards to health; Surgical or other procedure not carried out because of patient's decision; Abdominal pain, left lower quadrant; Renal dialysis status; Thrombocytopenia, unspecified; Anemia of other chronic disease; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Peripheral vascular disease, unspecified; Acquired absence of organ, eye; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus]" +109,189332.0,14865,2142-08-30,14862,131376.0,2142-07-08,Discharge summary,"Admission Date: [**2142-7-7**] Discharge Date: [**2142-7-8**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**Last Name (NamePattern1) 293**] +Chief Complaint: +dyspnea, Hypertension Urgency + +Major Surgical or Invasive Procedure: +Hemodialysis + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +admitted [**Date range (1) 43607**] after presenting for hypertensive urgency and +dyspnea for which she was started on nitroglycerin and labetalol +drips, which were weaned off in the ICU. She was also received +2U PRBCs during HD. She was discahrged home without any changes +to her medical regimen. +. +On the afternoon of [**7-4**] she notes increased dyspnea, she +therefore went to HD on Wednesday, and again on Thursday [**7-5**]. +After HD, her BP remained elevated, and she took an extra dose +of labetalol 1000mg x 1. On [**7-6**] her VNA noted SBP 250s. She +took extra doses of hydralazine, but otherwise felt well. She +then woke up this morning with HA. She took all of her BP meds +this morning, but remained with HA and SOB, thus prompting her +presentation to the ED. +. +No fevers, productive cough, taking all meds, had chronic +diarrhea that is unchanged, some n/v at baseline, no coffee +ground emesis, has some abdominal pain unchanged from baseline + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + + +Family History: +No known autoimmune disease. + +Pertinent Results: +08:00a +ALK,ALT,AST,CK,CPIS,LIP,BILI,TNT ADDED 12:29PM +141 103 29 82 AGap=13 + +3.4 28 6.5 ∆ +CK: 59 MB: Notdone Trop-T: 0.18 + +ALT: 21 AP: 126 Tbili: 0.4 Alb: +AST: 51 LDH: Dbili: TProt: +[**Doctor First Name **]: Lip: 56 + +PT: 15.0 PTT: 35.5 INR: 1.3 + + +N:69.8 L:21.9 M:5.5 E:2.5 Bas:0.3 +Hypochr: 1+ Anisocy: 2+ Macrocy: 1+ Microcy: 1+ Polychr: 1+ + + +Brief Hospital Course: +# Hypertensive Urgency - At the time of admission, the patient +denied chest pain but continued to have mild headache. She also +had resolving shortness of breath, likely secondary to +hypertension. She stated that she did take her PO meds. She +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. A sent of cardiac enzymes was sent and revealed a +CPK of 59 and a troponin of 0.18. The patient also underwent +dialysis in the ICU. After dialysis the labetalol drip was +weaned off. Overnight, SBP's ranged 109 to 182 mmHg. The +following day, her SBP's ranged 133 to 200. Ultimately, she was +discharged home on her normal medication regimen. + +# Abdominal Pain - The patient also presented complaining of +adbominal pain. She had recently been treated for SBO; however, +at the time of admit, she was without nausea or vomiting. She +had a soft abdomen, was passing flatus, and was having daily +bowel movements. She did have hypoactive bowel sounds. She was +continued of her outpatient pain regimen of PO dilaudid, +fentanyl patch, and lidoacine patch. An ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +Considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. This +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. After the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent SBO. + +# ESRD on HD - The patient gets hemodialysis on a Tu/Th/Sa +schedule. On admit, the patient was continued on her home does +of sevalemer. Renal was consulted, and the patient received +dialysis on [**7-7**] in the ICU. + +# Anemia/Pancytopenia - The patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her CKD and +SLE. On admit she was actually above baseline. She was +continued on her home does of epogen. + +# H/o Gastric Ulcer - The patient was continued on her PPI [**Hospital1 **]. + + +# SLE - The patient was continued on her home regimen of +prednisone 4mg po daily. + +# H/o SVC Thrombosis - The patient has a goal INR of [**2-13**]. +However, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic INR. On admit, her INR was +sub-therapeutic. Therefore, her warfarin was restarted at 3 mg +daily. + +# Seizure Disorder - The patient was continued on her home +regimen of keppra 1000 mg PO 3 times a week (Tu/Th/Sa). + +# Depression - The patient was continued on her home dose of +celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24HR (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +Disp:*QS Tablet(s)* Refills:*2* +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). +17. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for abdominal pain. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Hypertensive Urgency +Lupus Nephritis +End stage renal disease on hemodialysis +Ascites + + +Discharge Condition: +hemodynamically stable with blood pressures 130-140/70-80s. + + +Discharge Instructions: +You were evaluated and treated for you hypertension. You were +started on IV medications and transitioned to your home regimen +and received a session of hemodialysis. + +You also had an ultrasound to evaluate the fluid in your belly. +There was no evidence of blood clot contributing to the build up +of the fluid. + +Please continue to follow a low sodium diet at home and take all +of your blood pressure medications in addition to going to +dialysis. + +Followup Instructions: +You have the following appointments scheduled: +Please also keep your Tuesday/Thursday/Saturday Dialysis +schedule + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",53,2142-07-07 10:01:00,2142-07-08 18:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,HYPERTENSION," +# hypertensive urgency - at the time of admission, the patient +denied chest pain but continued to have mild headache. she also +had resolving shortness of breath, likely secondary to +hypertension. she stated that she did take her po meds. she +was started on a labetalol drip and continued on her home +regimen of oral labetolol, nifedipine, hydralazine, and +aliskerin. a sent of cardiac enzymes was sent and revealed a +cpk of 59 and a troponin of 0.18. the patient also underwent +dialysis in the icu. after dialysis the labetalol drip was +weaned off. overnight, sbps ranged 109 to 182 mmhg. the +following day, her sbps ranged 133 to 200. ultimately, she was +discharged home on her normal medication regimen. + +# abdominal pain - the patient also presented complaining of +adbominal pain. she had recently been treated for sbo; however, +at the time of admit, she was without nausea or vomiting. she +had a soft abdomen, was passing flatus, and was having daily +bowel movements. she did have hypoactive bowel sounds. she was +continued of her outpatient pain regimen of po dilaudid, +fentanyl patch, and lidoacine patch. an ultrasound of her abd +was also performed and showed ascites in all 4 quadrants with +the largest in the left lower quadrant measuring 5.5cm. +considering her history of thrombosis, renal recommended getting +an abdominal ultrasound with doppler flow studies. this +ultrasound showed mild to moderate ascites, a 9mm hemangioma, +and no evidence of thrombosis. after the results of this +ultrasound were reviewed, the patient was discharged home with a +plan to follow-up with liver regarding her ascites and whether +it can be attributed to her recent sbo. + +# esrd on hd - the patient gets hemodialysis on a tu/th/sa +schedule. on admit, the patient was continued on her home does +of sevalemer. renal was consulted, and the patient received +dialysis on [**7-7**] in the icu. + +# anemia/pancytopenia - the patient has a chronic anemia and +baseline pancytopenia that are likely secondary to her ckd and +sle. on admit she was actually above baseline. she was +continued on her home does of epogen. + +# h/o gastric ulcer - the patient was continued on her ppi [**hospital1 **]. + + +# sle - the patient was continued on her home regimen of +prednisone 4mg po daily. + +# h/o svc thrombosis - the patient has a goal inr of [**2-13**]. +however, naticoagulation was stopped after a recent admission +secondary to a supratherapeutic inr. on admit, her inr was +sub-therapeutic. therefore, her warfarin was restarted at 3 mg +daily. + +# seizure disorder - the patient was continued on her home +regimen of keppra 1000 mg po 3 times a week (tu/th/sa). + +# depression - the patient was continued on her home dose of +celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Unspecified iridocyclitis; ; Other ascites; Other chronic pain; Abdominal pain, unspecified site; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,189332.0,14865,2142-08-30,14860,136572.0,2142-06-20,Discharge summary,"Admission Date: [**2142-6-18**] Discharge Date: [**2142-6-20**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2145**] +Chief Complaint: +Acute Onset Dyspnea + +Major Surgical or Invasive Procedure: +Dialysis + + +History of Present Illness: +Please see MICU note for full details. In brief this is a 24 +y.o. woman with SLE, ESRD on HD, hx malignant HTN, h/o SVC +syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, frequently admitted +with hypertensive urgency/emergency who was admitted with acute +onset dyspnea after 2 weeks without dialysis given to unable to +get transportation ? despite Dr. [**Last Name (STitle) 7473**] attempting to arrange +transport for her (? refused to come). She was admitted +therefore on [**6-18**] to micu with VS: T 100.4 HR 108 BP 240/180 RR +28 POx100 RA. She was treated with nitro gtt, labetolol gtt and +dilaudid-these gtts were stopped at 0700. In the micu she was +dialyzed with 1.7L fluid removal (though + 300cc given +tranfusion). Her SOB is improved. Her hct was also noted to be +low (18->from 22 [**2142-6-5**]) so transfused 2 units PRBC's, recent +EGD with gastric ulcer [**5-29**], guaiac negative in ED, no BM in +unit, hemolysis w/u negative. BP in icu 140/106 currently but of +note was hypotensive on HD to 86/62. She notes sob improved +rapidly on arrival. + +ROS: Currently she has no complaints. She notes at home her +abdominal pain is at baseline for her, felt mid epigastric, for +which she takes dilaudid 4mg up to [**Hospital1 **]. She has been getting HD +via right femoral catheter which is not painful, no discharge +from the sight. She denies HA, visual changes, cough, chest pain +or pressure, orthostatic changes, palpitations, nausea, +vomiting, constipation, diarrhea, melena, brbpr, dysuria, +hematuria, rash, swelling, orthopnea, pnd. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - T: 97.7, BP: 140/99 P: 88 R: 19 O2: 98% on RA +General: Sleeping comfortably but awakens easily, alert, +oriented x3 +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM, moon facies +Neck: supple, JVP flat, no LAD, full ROM, left EJ in place +Lungs: coarse BS throughout, no W/R/R, no decreased BS at bases + +CV: S1, S2 nl, no m/r/g appreciated +Abdomen: Firm, non-tender to palpation, no masses or +organomegally +Ext: Warm, well perfused, 1+ DP/PT, no clubbing, cyanosis or +edema +Neuro: a&o x3, motor [**5-15**] UE/LE bilaterally + + +Pertinent Results: +[**2142-6-18**] 05:28PM HCT-26.0*# +[**2142-6-18**] 11:38AM HYPOCHROM-2+ ANISOCYT-1+ POIKILOCY-1+ +MACROCYT-NORMAL MICROCYT-OCCASIONAL POLYCHROM-NORMAL OVALOCYT-1+ +SCHISTOCY-OCCASIONAL TEARDROP-OCCASIONAL +[**2142-6-18**] 05:04AM GLUCOSE-85 UREA N-72* CREAT-10.4* SODIUM-139 +POTASSIUM-5.5* CHLORIDE-109* TOTAL CO2-14* ANION GAP-22* +[**2142-6-18**] 05:04AM LD(LDH)-264* TOT BILI-0.2 +[**2142-6-18**] 05:04AM CALCIUM-6.6* PHOSPHATE-6.5* MAGNESIUM-1.6 +[**2142-6-18**] 05:04AM HAPTOGLOB-142 +[**2142-6-18**] 05:04AM WBC-3.4* RBC-1.93* HGB-5.8* HCT-17.0* MCV-88 +MCH-30.0 MCHC-34.2 RDW-18.4* +[**2142-6-18**] 05:04AM PLT COUNT-97* +[**2142-6-18**] 01:34AM GLUCOSE-84 UREA N-70* CREAT-10.5*# SODIUM-136 +POTASSIUM-5.6* CHLORIDE-108 TOTAL CO2-14* ANION GAP-20 +[**2142-6-18**] 01:34AM estGFR-Using this +[**2142-6-18**] 01:34AM ALT(SGPT)-10 AST(SGOT)-39 ALK PHOS-108 TOT +BILI-0.2 +[**2142-6-18**] 01:34AM LIPASE-115* +[**2142-6-18**] 01:34AM ALBUMIN-3.2* CALCIUM-6.6* PHOSPHATE-6.8* +MAGNESIUM-1.7 +[**2142-6-18**] 01:34AM WBC-4.5 RBC-2.08* HGB-6.0* HCT-18.3* MCV-88 +MCH-28.6 MCHC-32.5 RDW-18.6* +[**2142-6-18**] 01:34AM NEUTS-78.5* LYMPHS-16.5* MONOS-3.0 EOS-1.4 +BASOS-0.6 +[**2142-6-18**] 01:34AM PLT COUNT-104* +[**2142-6-18**] 01:34AM PT-15.0* PTT-33.6 INR(PT)-1.3* + +Brief Hospital Course: +# Dyspnea: Pt's dypsnea improved on admission to the ED prior to +HD. Based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. Upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# Anemia: Pt's baseline 1 month ago noted to be low 30s, since +then her Hct has trended down to 22 several week prior to +admission. As she missed dialysis she was not able to reserve +her Eopgen which likely complicated her anemia. Pt underwent +hemolysis workup in the ICU which was ultimately negative. She +was given several units of PRBC and bumped her Hct +appropriately. She was noted to be guaiac negative on +examination. + +# Hypertension: Pt was initially admitted with hypertension. +Following transition to the floor she was placed on her home +regimen. She was noted to be hypotensive in dialysis which is +likely due to her being on Labetalol, Nitro gtt on dialysis. Pt +was discharged on her home BP regimen with follow up with her +nephrologist. + +# Chronic Abdominal Pain: Pt had noted some intermittent +abdominal pain which has been chronic. Lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. Pt was able to tolerate a PO diet prior to her +discharge. Pt was continued on her outpatient regimen of +Dilaudid, Fentanyl patch, Neurontin. + +# GE junction Ulcer: Pt was continued on her PPI regimen [**Hospital1 **]. + +# SLE: Pt was continued on her home regimen of Prednisone 4mg +daily + +# History of DVT: Pt had a sub-therapeutic INR on admission. She +was discharged on Warfarin 3mg daily. + +# ESRD on HD: Pt was admitted for dyspnea in the setting of +missing 2 weeks of HD. The renal team followed Ms. [**Known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. Pt was continued on Sevelamer and +Epogen. + +# Seizure D/O: Pt was continued on her home regimen of keppra. + +# Depression: Pt was continued on her home regimen of Celexa. + + +Medications on Admission: +1. Nifedipine 90 mg Tablet Sustained Release PO QAM +2. Nifedipine 60 mg Tablet Sustained Release PO QHS +3. Lidocaine 5 % transdermal one daily +4. Aliskiren 150 mg PO BID +5. Citalopram 20 mg PO DAILY (Daily). +6. Fentanyl 25 mcg/hr Patch Q72H (every 72 hours). +7. Prednisone 4mg PO DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Transdermal QSAT +9. Clonidine 0.3 mg/24 hr Patch Weekly Transdermal QSAT +10. Sevelamer HCl 400 mg Four (4) Tablet PO TID W/MEALS +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +13. Hydralazine 100 mg PO Q8H +14. Hydromorphone 2 mg 1-2 Tablets PO Q6H as needed for pain. +15. Pantoprazole 40 mg PO Q12H +16. LeVETiracetam 1,000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24 H (). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary: Malignant HTN, ESRD on HD, Shortness of breath +Secondary: Lupus + + +Discharge Condition: +Stable, afebrile + + +Discharge Instructions: +You were admitted to the hospital after you noticed some +shortness of breath. Whilst in the hospital you were noted to +have a low blood level (anemia) and you some fluid in your +lungs. We think your blood level was low because you were not +receiving your Epo shots, we think the fluid is from not +receiving dialysis. Before you were discharged from the hospital +your breathing was better. + +We recommend that you continue going to dialysis. + +We made no changes to your medications. + +If you notice any fevers, chills, nausea, vomiting, shortness of +breath, lightheadedness please return to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 +Provider: [**First Name4 (NamePattern1) **] [**Name Initial (NameIs) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-27**] 2:00 + + + [**Name6 (MD) **] [**Name8 (MD) **] MD [**MD Number(2) 2158**] + +",71,2142-06-18 03:11:00,2142-06-20 16:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ANEMIA," +# dyspnea: pts dypsnea improved on admission to the ed prior to +hd. based on her imaging studies her dyspnea was likely related +to fluid overload (pt missed 2 weeks of dialysis) and her level +of anemia. upon transfer to the floor she was continued on her +dialysis regimen and discharged on room air. + +# anemia: pts baseline 1 month ago noted to be low 30s, since +then her hct has trended down to 22 several week prior to +admission. as she missed dialysis she was not able to reserve +her eopgen which likely complicated her anemia. pt underwent +hemolysis workup in the icu which was ultimately negative. she +was given several units of prbc and bumped her hct +appropriately. she was noted to be guaiac negative on +examination. + +# hypertension: pt was initially admitted with hypertension. +following transition to the floor she was placed on her home +regimen. she was noted to be hypotensive in dialysis which is +likely due to her being on labetalol, nitro gtt on dialysis. pt +was discharged on her home bp regimen with follow up with her +nephrologist. + +# chronic abdominal pain: pt had noted some intermittent +abdominal pain which has been chronic. lipases were noted to be +mildl elevated however no other concerning physical exam signs +of pancreatitis. pt was able to tolerate a po diet prior to her +discharge. pt was continued on her outpatient regimen of +dilaudid, fentanyl patch, neurontin. + +# ge junction ulcer: pt was continued on her ppi regimen [**hospital1 **]. + +# sle: pt was continued on her home regimen of prednisone 4mg +daily + +# history of dvt: pt had a sub-therapeutic inr on admission. she +was discharged on warfarin 3mg daily. + +# esrd on hd: pt was admitted for dyspnea in the setting of +missing 2 weeks of hd. the renal team followed ms. [**known lastname **] during +her hospitalization and she was continued on her outpatient +regimen of hemodialysis. pt was continued on sevelamer and +epogen. + +# seizure d/o: pt was continued on her home regimen of keppra. + +# depression: pt was continued on her home regimen of celexa. + + + ","PRIMARY: [] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Anemia of other chronic disease; Hyperpotassemia; Systemic lupus erythematosus; Abdominal pain, other specified site; Other chronic pain; Hypotension, unspecified; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Depressive disorder, not elsewhere classified; Personal history of venous thrombosis and embolism; Noncompliance with renal dialysis]" +109,189332.0,14865,2142-08-30,14861,174489.0,2142-07-04,Discharge summary,"Admission Date: [**2142-7-3**] Discharge Date: [**2142-7-4**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 2817**] +Chief Complaint: +dyspnea, hypertension + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +24F h/o SLE, ESRD on HD, h/o malignant HTN, SVC syndrome, PRES, +prior ICH, with frequent admission for hypertensive +urgency/emergency, with chronic abdominal pain. She was recently +discharged on [**7-1**] after presenting for hypertensive urgency and +dyspnea for which she received iv medication in the ED, but was +otherwised managed with oral antihypertensives and CPAP. +. +She was doing well until the evening of [**7-2**] when she notes the +gradual onset of dyspnea. She denied f/c/cp/ha/abd +pain/diarrhea, or constipation. She was having regular, soft, +daily BMs. +. +On [**7-3**] she awoke, and describes n/v x 2, with increasing +dyspnea, and headache. She did not want to wait until dialysis +at 4PM and therefore presented to [**Hospital1 18**]. +. +In ED VS= 97.7 [**Telephone/Fax (2) 43606**] 100%RA. Labs were notable for HCT +23, PLT 66, WBC 3.3, all roughly at baseline. CXR without acute +process, ECG unchanged from prior. No UA sent, though she does +make some urine. She was started on nitro gtt with modest +improvement of SBPs to 210s, then labetalol 20mg iv x1 followed +by labetalol gtt with BP 221/130 at the time of transfer. She +refused abdominal CT. Renal was consulted, but felt HD not +indicated today. +. +. +ROS: Negative for fevers, chills, chest pain, diarrhea, rash, +joint pains. +n/v as above. +abdominal pain unchanged from her +baseline. +dyspnea, +HA. denies visual changes, slurrring +speech, numbness, weeakness. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +Vitals - 97.7 88 220/150 19 100%2L BC. +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM. +Neck: supple, no LAD, full ROM. +Lungs: CTA B, with few crackles at bases. +CV: RR, nl S1, S2 +S3, no rubs appreciated. +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation, negative [**Doctor Last Name **], no rebound, gaurding. +Ext: WWP, 1+ dp/pt pluses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +Lab Results on Admission: + +[**2142-7-3**] 11:37AM GLUCOSE-95 UREA N-40* CREAT-7.4*# SODIUM-140 +POTASSIUM-3.8 CHLORIDE-105 TOTAL CO2-23 ANION GAP-16 +ALT(SGPT)-14 AST(SGOT)-44* LD(LDH)-264* ALK PHOS-115 TOT +BILI-0.4 ALBUMIN-3.2* +WBC-3.6* RBC-2.61* HGB-7.6* HCT-23.4* MCV-90 MCH-29.0 MCHC-32.4 +RDW-18.3* +[**2142-7-3**] 11:37AM NEUTS-71.6* LYMPHS-23.0 MONOS-3.7 EOS-1.5 +BASOS-0.2 PLT COUNT-66* PT-14.0* PTT-34.5 INR(PT)-1.2* +[**2142-7-3**] 06:00PM CK-MB-5 cTropnT-0.17*CK(CPK)-58 + +[**2142-7-3**] CXR: +IMPRESSION: Unchanged moderate cardiomegaly with pulmonary +edema. Again +underlying pneumonia in the lung bases cannot be completely +excluded and +evaluation after appropriate diuresis could be performed if +pneumonia remains a clinical concern. + + +Brief Hospital Course: +24F with h/o SLE, ESRD on HD, malignant HTN, h/o SVC syndrome, +PRES, prior ICH, and recent SBO, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - On presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her PO +meds. Hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below SBP 120. She evenutally became hypotensive to SBP +of 90 which resolved on its own. She was continued on CPAP +overnight and discontinued in the am. She was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. She remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - On presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. She +did have hypoactive bowel sounds on admission. She was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with HD with plan to follow BMs +closley. Her pain improved the am of discharge and she had no +further vomiting. +. +# ESRD on HD - She is currently getting HD SaTuTh, though did +not get HD on the day of presenation. As there was no acute +indication for HD on presentation, she received HD on the +following am, day of discharge. She was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] CKD and SLE, currently +above baseline, though has h/o GIB. She received 2 unit PRBCs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of PPI [**Hospital1 **]. +. +# SLE - continue home regimen of prednisone 4mg po qdaily. +. +# h/o SVC thrombosis - pt with goal INR [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic INR. INR +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg PO 3X/WEEK +(TU,TH,SA). +. +# depression - continued on celexa. + + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO DAILY (Daily). +2. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO HS (at bedtime). +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical Q24H (every 24 hours). + +4. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) patch Transdermal +every seventy-two (72) hours. +6. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +7. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for hypertension. +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +11. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. +12. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). Tablet(s) +14. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +15. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +16. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QTUTHSA +(TU,TH,SA). + + +Discharge Disposition: +Home With Service + +Facility: +VNA + +Discharge Diagnosis: +Primary: +hypertensive emergency +anemia, erythropoetin deficiency + +Secondary: +chronic renal failure on hemodialysis +lupus nephritis + + +Discharge Condition: +Hemodynamically stable. + + +Discharge Instructions: +You were admitted for hypertensive urgency and treated in the +intensvie care unit with IV medications to decrease your blood +pressure. You also received 2 units of blood and hemodialysis +before you were discharged home. + +It is essential that you take all of your prescribed blood +pressure medications and present regularly for your Tuesday, +Thursday, Saturday dialysis. + +Please return to the emergency department or call your primary +care physician if you develop any chest pain, shortness of +breath, fevers, or any other concerning symptoms. + +Followup Instructions: +You have the following appointment scheduled. Please contact +your provider if you are unable to make these appointments. + +Your dialysis is scheduled for Tuesday, Thursday, Saturday. + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +",57,2142-07-03 14:48:00,2142-07-04 17:23:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSION," +24f with h/o sle, esrd on hd, malignant htn, h/o svc syndrome, +pres, prior ich, and recent sbo, p/w n/v, and hypertensive +urgency. +. +# hypertensive urgency - on presentation she denies chest pain, +but continues to have mild headache, and resolving shortness of +breath, likely [**2-12**] hypertension. states she did take her po +meds. hypertensive urgency was treated as follows with nitro and +labetalol gtt which were quickly weaned as blood pressures +dropped below sbp 120. she evenutally became hypotensive to sbp +of 90 which resolved on its own. she was continued on cpap +overnight and discontinued in the am. she was continued on her +home regimen of oral labetolol, nifedipine, hydralazine, +aliskerin. she remained normotensive the following morning and +was taken to hemodialysis after which she was discharged home on +all of her old home medications. +. +# abdominal pain - on presentation she was without n/v, soft +abdomen, passing flatus, and having daily bowel movements. she +did have hypoactive bowel sounds on admission. she was +maintained on outpt pain regimen of po dilaudid, fentanyl patch, +lidoacine patch, neurontin with hd with plan to follow bms +closley. her pain improved the am of discharge and she had no +further vomiting. +. +# esrd on hd - she is currently getting hd satuth, though did +not get hd on the day of presenation. as there was no acute +indication for hd on presentation, she received hd on the +following am, day of discharge. she was continued on sevelamer. + +. +# anemia - chronic anemia, likely [**2-12**] ckd and sle, currently +above baseline, though has h/o gib. she received 2 unit prbcs +and epo with hemodialysis. +. +# h/o gastric ulcer - she was continued on her outpatient dose +of ppi [**hospital1 **]. +. +# sle - continue home regimen of prednisone 4mg po qdaily. +. +# h/o svc thrombosis - pt with goal inr [**2-13**], but this was +stopped after recent admission [**2-12**] supratherapeutic inr. inr +currently sub-therapeutic and she was resumed on warfarin at 3 +mg qdaily without heparin bridge. +. +# seizure disorder - continued on keppra 1000 mg po 3x/week +(tu,th,sa). +. +# depression - continued on celexa. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Unspecified iridocyclitis; Other primary cardiomyopathies; Abdominal pain, unspecified site; Other chronic pain; Nausea with vomiting; Systemic lupus erythematosus; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Other specified peripheral vascular diseases; Obstructive sleep apnea (adult)(pediatric); Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,189332.0,14865,2142-08-30,14858,151240.0,2142-05-18,Discharge summary,"Admission Date: [**2142-5-15**] Discharge Date: [**2142-5-18**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 613**] +Chief Complaint: +Headache, Hypertensive urgency + +Major Surgical or Invasive Procedure: +Hemodialysis x 2 + + +History of Present Illness: +24 year old female with SLE, ESRD on HD, hx malignant HTN, h/o +SVC syndrome, h/o posterior reversible encephalopathy syndrome +(PRES) and prior intracerebral hemorrhage, recently admitted +[**Date range (1) 17717**] with diarrhea, hypertensive urgency. Treated at that +time with nicardipine drip for a short period and then to her +home regimen. Yesterday onset of nausea with emesis and +inability to tolerate home meds including antihypertensives. +Diarrhea mild as prior. No fever, chills, no hematemesis or +hematochezia. No melena. Today reports onset of headache +therefore to the ED. + +In the ED, initial vs were 280/160, 99.4, 105, RR 18. She was +given dilaudid 2 mg PO x 2. Hydral 20 mg x 3 for BP. Calcium +gluconate 1 gram. Insulin 10 units, D 50 [**1-12**] amp, sodium +bicarbonate, kayexalate for K 6.7 (dialysis dependent +Tues/thurs/sat) but with report of peaked T waves. Renal +dialysis fellow was not contact[**Name (NI) **]. HCT 33.4, WBC 4.6, trop 0.10. +Admitted for hypertensive urgency to ICU. No gtt was started. Of +note usualy BP 160/100. + +Review of sytems: +patient tearful complaining of frontal headache and nausea + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD with intermittent refusal of dialysis, currently only + +agrees to be dialyzed one time/wk +3. Malignant hypertension with baseline SBP's 180's-120's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother. On disability for multiple medical problems. + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather + +Physical Exam: +Vitals: BP 240/146, 101, 98.6, +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: tachycardic, 3/6 SEM RUSB +Abdomen: soft, diffusely tender, no rebound or gaurding. +Ext: cachectic, warm, 2+ DP pulse no clubbing, cyanosis or edema + + +Pertinent Results: +[**2142-5-15**] 05:45AM GLUCOSE-83 UREA N-54* CREAT-7.6* SODIUM-138 +POTASSIUM-6.7* CHLORIDE-103 TOTAL CO2-23 ANION GAP-19 +[**2142-5-15**] 05:45AM CK(CPK)-96 +[**2142-5-15**] 05:45AM cTropnT-0.10* +[**2142-5-15**] 05:45AM CK-MB-NotDone +[**2142-5-15**] 05:45AM WBC-4.6 RBC-3.66* HGB-10.8* HCT-33.4* MCV-91 +MCH-29.6 MCHC-32.4 RDW-17.9* +[**2142-5-15**] 05:45AM NEUTS-65.4 LYMPHS-25.1 MONOS-4.8 EOS-4.1* +BASOS-0.7 +[**2142-5-15**] 05:45AM PLT COUNT-128* +[**2142-5-15**] 05:45AM PT-14.2* PTT-36.4* INR(PT)-1.2* +[**2142-5-15**] 07:14AM K+-6.0* +[**2142-5-15**] 12:17PM K+-5.3 + +Images: +CXR: Persistent severe cardiomegaly. + +Head CT: Normal brain CT. + +Brief Hospital Course: +24 yo female with ESRD on HD, malignant hypertension with hx of +intracerebral hemorrhage, SLE, chronic abdominal pain, and SVC +syndrome admitted due to hypertensive urgency after developing +N/V and being unable to take her po medications. + +# Hypertensive urgency: The patient was admitted to the MICU the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head CT was negative for +intracranial bleed. She was continued on her home regimen of +Aliskiren 150 mg po bid, Clonidine 0.4 mg/24 hr Patch Weekly, +Labetalol 1000 mg po TID, Nifedipine 60 mg Tablet Sustained +Release QPM and 90 mg Tablet Sustained Release QAM, and +Hydralazine 100 mg PO Q8H. During her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. Blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). She was discharged +on her home regimen. + +# Nausea/vomiting: The patient did not experience further +vomiting, but occasionally complained of nausea. The cause of +her nausea was unclear. She was able to tolerate po intake +prior to discharge. + +# Abdominal pain/Diarrhea: The patient has chronic abdominal +pain with previous negative workups. During this hospitalization +her pain was at its baseline. Since admission she denied +diarrhea. She was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# ESRD on HD: She was hyperkalemic in the emergency room and was +given kayexalate. She underwent two sessions of dialysis during +this hospitalization. + +# SLE: Stable, without symptoms. She was continued on 4 mg of +prednisone daily. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient, however her INR +was subtherapeutic on admission at 1.2. Previous documentation +in OMR states she does not need to be bridged while +subtherapeutic. She was initally continued on coumadin 4 mg po +daily, however her INR rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# OSA: She is on CPAP at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + +Medications on Admission: +Medications: as per last discharge summary +-Aliskiren 150 mg Tablet [**Hospital1 **] +-Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday) +-Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +-Labetalol 200 mg Tablet Sig 5 tab TID +-Nifedipine 60 mg Tablet Sustained Release QPM +-Nifedipine 90 mg Tablet Sustained Release QAM +-Citalopram 20 mg Tablet Sig daily +-Hydromorphone 2 mg Tablet Sig [**1-12**] Q4 PRN +-Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H +-Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO BID PRN +-Prednisone 4 mg daily +-Coumadin 4 mg daily at 4 PM + +Discharge Medications: +1. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +2. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QWED (every Wednesday). +3. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +6. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QPM (once a day (in the evening)). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +9. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +10. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +11. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours. +12. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for hypertension. +13. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO Once Daily at +4 PM. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary - +Hypertensive urgency +End-stage renal disease on dialysis + +Secondary - +Systemic lupus erythematous +History of thombosis and Superior vena cava syndrome +Obstructive sleep apnea + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted to the hospital due to dangerously elevated +blood pressure due to inability to take your medications +secondary to nausea. It is very important that you take your +blood pressure medications reguarly. Your nausea was controlled +with medication and your blood pressure decreased once back on +your home medication regimen. + +You underwent two sessions of dialysis during your +hospitalization. It is extremely important that you attend +dialysis three times weekly as an outpatient. + +Medication changes: +You should be taking 3 mg of coumadin daily. You will need to +have your INR checked at dialysis. + +Otherwise continue your outpatient medications as prescribed. + +Call your primary doctor, or go to the emergency room if you +experience fevers, chills, worsening headache, vision change, +inability to take your medications, blood in your stool, or dark +black stool. + +Followup Instructions: +It is very important that you keep your previously scheduled +appointments: + +You have an appointment with gynecology to evaluate an +abnormality recently seen on PAP smear. Provider: [**First Name4 (NamePattern1) **] +[**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2664**] Date/Time:[**2142-5-25**] 9:30 + +Provider: [**First Name8 (NamePattern2) 2353**] [**Last Name (NamePattern1) 4758**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-6-1**] 2:00 + + + [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 617**] + +Completed by:[**2142-5-19**]",104,2142-05-15 10:45:00,2142-05-18 15:58:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPERTENSIVE CRISIS," +24 yo female with esrd on hd, malignant hypertension with hx of +intracerebral hemorrhage, sle, chronic abdominal pain, and svc +syndrome admitted due to hypertensive urgency after developing +n/v and being unable to take her po medications. + +# hypertensive urgency: the patient was admitted to the micu the +night of admission where she was placed on a labetolol drip and +her home medications were restarted. head ct was negative for +intracranial bleed. she was continued on her home regimen of +aliskiren 150 mg po bid, clonidine 0.4 mg/24 hr patch weekly, +labetalol 1000 mg po tid, nifedipine 60 mg tablet sustained +release qpm and 90 mg tablet sustained release qam, and +hydralazine 100 mg po q8h. during her stay her blood pressure +fluctuated, occasionally becoming relatively low due to grouping +of her medications together. blood cultures were sent but have +been no growth to date and she remained without signs of +infection (afebrile with no leukocytosis). she was discharged +on her home regimen. + +# nausea/vomiting: the patient did not experience further +vomiting, but occasionally complained of nausea. the cause of +her nausea was unclear. she was able to tolerate po intake +prior to discharge. + +# abdominal pain/diarrhea: the patient has chronic abdominal +pain with previous negative workups. during this hospitalization +her pain was at its baseline. since admission she denied +diarrhea. she was continued on her outpatient regimen of [**2-14**] mg +po dilaudid q4h as needed. + +# esrd on hd: she was hyperkalemic in the emergency room and was +given kayexalate. she underwent two sessions of dialysis during +this hospitalization. + +# sle: stable, without symptoms. she was continued on 4 mg of +prednisone daily. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient, however her inr +was subtherapeutic on admission at 1.2. previous documentation +in omr states she does not need to be bridged while +subtherapeutic. she was initally continued on coumadin 4 mg po +daily, however her inr rose quickly to the therapeutic range, so +this was decreased to 3 mg po daily. + +# osa: she is on cpap at a setting of 7 as an outpatient and was +continued on this during her hospitalization. + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Hyperpotassemia; Nausea with vomiting; Diarrhea; Disorders of phosphorus metabolism; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Long-term (current) use of anticoagulants; Noncompliance with renal dialysis; Renal dialysis status; Personal history of noncompliance with medical treatment, presenting hazards to health]" +109,189332.0,14865,2142-08-30,14863,196721.0,2142-07-23,Discharge summary,"Admission Date: [**2142-7-12**] Discharge Date: [**2142-7-23**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 759**] +Chief Complaint: +Dyspnea, hypertension + +Major Surgical or Invasive Procedure: +1. Ultrasound Guided Tap +2. Venogram + + +History of Present Illness: +Ms. [**Known lastname **] is a 24 year old female with a history of SLE, ESRD on +HD, h/o malignant HTN, SVC syndrome, PRES, prior ICH, with +frequent admission for hypertensive urgency/emergency, with +chronic abdominal pain that presented to the ED [**7-12**] with +critically high blood pressure and dyspnea. She was recently +discharged on [**7-8**] for hypertensive urgency and dyspnea. She +was treated with labetolol gtt, [**Month/Year (2) 2286**], and her home +medications with improvement of her BP. She was discharged home +in stable condition on [**7-8**]. She had been doing well at home, +but missed her HD session on [**7-10**] due to transportation issues. +She has been taking her medications without any difficulty. On +the morning of admission, she noted increase dyspnea, and had a +dry cough, although this is not particularly new. She presented +to the ER for dyspnea. She continues to have the chronic +abdominal pain which is unchanged, and is controlled right now. + + +In the emergency department, VS= 98.1, 240/140, 128, 30, 96%RA. +On initial evaluation, she was noted to have SBP 70s on the +right arm, 240s on the left arm. She did not complain of any +pain. She underwent CTA torso to eval for dissection which was +negative for dissection or PE. The imaging showed persistent SVC +thrombus. There was also note of bilateral ground glass and +nodularities therefore was given levofloxacin 750 mg IV x 1. She +was given labetalol IV, then started on a labetalol gtt. Her BP +remained elevated, therefore she was transferred to the ICU for +BP control and then [**Month/Year (2) 2286**]. She was also given dilaudid 1 mg +IV x 1 as well. + +Ms. [**Known lastname **] was taken to the MICU and treated for malignant +hypertension. She was given hemodialysis and her blood pressure +stabilized. She was transferred to the medical floor. She +continued to receive [**Known lastname 2286**] Tuesday, Thursday, and Saturday. +On [**7-16**], she had a paracentesis of her abdomen. She is +complaining of focal tenderness around the point of insertion. +On [**7-17**], she was transferred back to the MICU because of stridor +that was treated with Heliox. She was stabilized, and came back +to the floor on [**7-19**]. On [**7-19**], Ms. [**Known lastname **] had a venogram. On +[**7-23**], an angiography intervention for an occlusion of her left +brachiocephalic vein was discontinued because her occlusion was +not as drastic as prior imaging indicated when tested with a 22 +gauge needle. Ms. [**Known lastname **] was discharged on [**7-23**] with stable +blood pressures and abdominal pain controlled. + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD 3. Malignant hypertension with baseline SBP's +180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Denies tobacco, alcohol or illicit drug use. Lives with mother +and is on disability for multiple medical problems. + +Family History: +No known autoimmune disease. + +Physical Exam: +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, + +Neck: supple, no LAD +Lungs: CTA B, with few crackles at bases. +CV: RRR, S1, S2 +Abdomen: soft, minimally distended, diffuse mild tenderness to +palpation +Ext: palpable DP/PT pulses, no clubbing, cyanosis or edema. +Neuro: CN 2-12 intact. moving all four extremities +spontaneously. + + +Pertinent Results: +[**2142-7-22**] 07:50AM BLOOD WBC-2.8* RBC-2.51* Hgb-7.3* Hct-23.1* +MCV-92 MCH-29.1 MCHC-31.8 RDW-21.1* Plt Ct-134* +[**2142-7-21**] 10:30AM BLOOD WBC-3.5* RBC-2.36* Hgb-6.8* Hct-21.6* +MCV-92 MCH-28.9 MCHC-31.6 RDW-20.5* Plt Ct-121* +[**2142-7-22**] 07:50AM BLOOD PT-14.7* PTT-35.0 INR(PT)-1.3* +[**2142-7-22**] 07:50AM BLOOD Glucose-154* UreaN-20 Creat-4.4* Na-138 +K-4.0 Cl-103 HCO3-23 AnGap-16 +[**2142-7-21**] 10:30AM BLOOD Vanco-17.8 +[**2142-7-20**] 09:35AM BLOOD WBC-3.8* RBC-2.39* Hgb-7.0* Hct-21.6* +MCV-90 MCH-29.2 MCHC-32.4 RDW-19.8* Plt Ct-120* +[**2142-7-19**] 12:30PM BLOOD WBC-3.6* RBC-2.49* Hgb-7.0* Hct-22.5* +MCV-90 MCH-28.3 MCHC-31.3 RDW-18.8* Plt Ct-121* +[**2142-7-20**] 09:35AM BLOOD Plt Ct-120* +[**2142-7-20**] 09:35AM BLOOD PT-19.7* PTT-38.4* INR(PT)-1.8* +[**2142-7-19**] 12:30PM BLOOD Plt Ct-121* +[**2142-7-19**] 12:30PM BLOOD PT-29.5* PTT-43.9* INR(PT)-2.9* +[**2142-7-20**] 09:35AM BLOOD Glucose-90 UreaN-19 Creat-4.2*# Na-138 +K-4.2 Cl-102 HCO3-25 AnGap-15 +[**2142-7-19**] 12:30PM BLOOD Glucose-72 UreaN-34* Creat-6.0*# Na-137 +K-4.5 Cl-102 HCO3-24 AnGap-16 +[**2142-7-19**] 12:30PM BLOOD Calcium-8.2* Phos-4.6* Mg-1.6 +[**2142-7-18**] 05:44AM BLOOD Calcium-8.9 Phos-5.1* Mg-1.7 +[**2142-7-12**] 12:27PM BLOOD [**Doctor First Name **]-POSITIVE * Titer-1:80 [**Last Name (un) **] +[**2142-7-12**] 12:27PM BLOOD C3-69* C4-17 +[**2142-7-19**] 12:30PM BLOOD Vanco-16.7 +[**2142-7-17**] 08:57AM BLOOD Vanco-15.9 +[**2142-7-14**] 04:16AM BLOOD Vanco-19.2 +[**2142-7-17**] 07:27AM BLOOD Type-ART pO2-66* pCO2-52* pH-7.30* +calTCO2-27 Base XS--1 +[**2142-7-12**] 02:06PM BLOOD Lactate-1.0 + + +Brief Hospital Course: +24 y/o female with h/o SLE, ESRD on HD, malignant HTN, h/o SVC +syndrome, PRES, prior ICH, and recent SBO, presented to ED on +[**7-12**] for dyspnea and hypertensive urgency. + +1. hypertensive urgency - pt presented to ER with SBP in 240s +and c/o dyspnea. Her blood pressures were reported as unequal +and CTA in ER was done. This study showed no signs of +dissection. Pt's blood pressure was controlled with labetalol +gtt. At time of transfer, she denied CP and SOB. CE's were +flat. She was started on her home BP regimen of oral labetalol +on [**2142-7-15**], and nifedipine/hydralazine/aliskerin soon after +admission. Pt was also continued on her HD regimen for ESRD, +for volume control. +. +2. angioedema - pt developed facial swelling and shortness of +breath while on medical floor. She was taken to ICU and +responded favorably to Heliox. Patient returned to floor and +has been comfortably breathing since. Given history of SVC, +venogram was ordered that did not indicate a complete occlusion +of the left brachiocephalic vein, as previously thought, with +help of 22 gauge needle. + +3. cough: pt presented with chronic cough/dyspnea without +fevers. Chest CT revealed bilateral infiltrates and +nodularities, noted possibly infectious vs edema. Pt was started +on vanc/zosyn given recent hospitalization, brief temp spike, +and pulm infiltrates. Abx were stopped after cultures were neg. +At time of transfer, pt's dyspnea was largely resolved and these +findings were felt to be more consistent with edema given +hypertensive urgency. +. +4. chronic abdominal pain - pt has had chronic abdominal pain, +which was well controlled at time of transfer. She was continued +on her current outpt pain regimen of po dilaudid, fentanyl +patch, lidoacine patch. Her LFTs and lipase were wnl. She had no +signs of SBO. +. +5. bacteremia - GPC in pairs and clusters; started on vanco on +[**2142-7-12**]. +. +6. Ascites - unclear etiology and new findings for her. Pt is +to get workup with liver team as outpatient. Her [**Date Range 2286**] seems +to have slightly improved this finding. Her coags were +unremarkable. She was seen by Hepatology in house who did not +have any specific recommendations at this time but asked to see +her in follow up as an outpatient. +. +7. ESRD on HD - HD SaTuTh,. Pt was continued on her HD regimen +while in house. Sevelamer was continued as well. +. +8. anemia/pancytopenia - chronic anemia, baseline pancytopenia, +likely [**2-12**] CKD and SLE, currently above baseline, though has h/o +GIB. Pt's pancytopenia remained stable; C3 and C4 studies were +performed and it was felt that her SLE was not active at this +time. Guiac stools were neg. EPO was continued at HD. +. +9. h/o gastric ulcer - PPI was continued throughout +hospitalization. +. +10. SLE - pt was continued on home regimen of prednisone 4mg po +qdaily. +. +11. h/o SVC thrombosis - patient's warfarin was discontinued +after discussion with Dr. [**Last Name (STitle) 4883**]. She frequently is outside +of therapeutic range on this medication and given the suspected +problems with medication compliance, it was felt it was safer to +discontinue it altogether. +. +12. seizure disorder - pt was continued on home regimen keppra +1000 mg PO 3X/WEEK (TU,TH,SA). +. +13. depression - pt was continued on her home celexa. +. + +Medications on Admission: +1.Nifedipine 90 mg PO DAILY (Daily). +2.Nifedipine 60 mg Tablet Sustained Release PO HS (at bedtime). + +3.Lidocaine 5 % PATCH Q24HR. +4.Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5.Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6.Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch Q72H +7.Prednisone 4 mg PO DAILY (Daily). +8.Clonidine 0.1 mg/24 hr Patch QSAT (every Saturday). +9.Clonidine 0.3 mg/24 hr Patch QSAT (every Saturday). +10.Sevelamer HCl 1600 mg PO TID W/MEALS (3 TIMES A DAY WITH +MEALS). +11.Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +12.Labetalol 1000 mg Tablet Tablet PO TID +13.Hydralazine 100 mg Tablet PO Q8H +14.Warfarin 3 mg Tablet PO Once Daily at 4 PM. +15.Pantoprazole 40 mg PO Q12H (every 12 hours). +16.Levetiracetam 1000 mg PO 3X/WEEK (TU,TH,SA). + +Discharge Medications: +1. Protonix 40 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO every twelve (12) hours. +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QTHUR (every Thursday). +3. Nifedipine 60 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO at bedtime. +4. Nifedipine 30 mg Tablet Sustained Release Sig: Three (3) +Tablet Sustained Release PO QAM (once a day (in the morning)). +5. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +6. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +7. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +8. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +9. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +10. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch +Weekly Transdermal every Thursday. +11. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +12. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +13. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day): Please hold if systolic blood pressure < 100 or HR < 55. + +14. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +15. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO 3X/WEEK +(TU,TH,SA). +16. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +17. Vancomycin 500 mg Recon Soln Sig: One (1) Recon Soln +Intravenous HD PROTOCOL (HD Protochol). +18. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for Constipation. +Disp:*60 Tablet(s)* Refills:*2* +19. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +Disp:*60 Capsule(s)* Refills:*2* +20. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every six (6) hours +as needed for pain: do not drive or operate heavy machinery with +this medication as it can cause drowsiness. +Disp:*20 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Malignant Hypertension +Angioedema +Ascites +End Stage Renal Disease + +Secondary: +Chronic Abdominal Pain +Anemia/Pancytopenia +Lupus +Gastric Ulcer +SVC Thrombosis +Seizure Disorder +Depression + + +Discharge Condition: +Hemodynamically stable with blood pressures 130-140 / 60-90 + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] on [**2142-7-12**] because of critically high +blood pressure. While here, you were given IV antihypertensive +medications, and then you were switched to antihypertnsive +medications by mouth. You received multiple sessions of +hemodialysis. You had a distended, tender belly, and you +underwent a ultrasound guided tap to remove the fluid in your +abdomen. On [**2142-7-17**], you developed throat and facial swelling, +and you were transferred from the medical floor to the ICU. You +were given medication to help open your airway; you were +stabilized and went to hemodialysis several times. You were +transferred back to the medical floor. You had a venogram on +[**2142-7-20**], and the results at this time are still pending. + +You had blood cultures drawn that were positive for bacteria. +You received IV antibiotics while at hemodialysis. You will +continue to receive these antibiotics at your appointments. + +Please keep all of your medical appointments. + +Please go to the nearest emergency room if you experience any of +the following: + +1. Chest Pain +2. Headaches +3. Lightheadedness +4. Changes in vision +5. Nausea and Vomiting + + +Followup Instructions: +Please continue your regular hemodialysis schedule. + +You have the following appointments scheduled. Please call if +you need to cancel or change your appointments. + +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-7-21**] +12:00 + +Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2142-7-30**] 2:00 + +Provider: [**Name10 (NameIs) 14201**] CLINIC Phone:[**Telephone/Fax (1) 2664**] +Date/Time:[**2142-8-8**] 3:15 + + + +Completed by:[**2142-7-24**]",38,2142-07-12 15:27:00,2142-07-23 18:41:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,SHORTNESS OF BREATH," +24 y/o female with h/o sle, esrd on hd, malignant htn, h/o svc +syndrome, pres, prior ich, and recent sbo, presented to ed on +[**7-12**] for dyspnea and hypertensive urgency. + +1. hypertensive urgency - pt presented to er with sbp in 240s +and c/o dyspnea. her blood pressures were reported as unequal +and cta in er was done. this study showed no signs of +dissection. pts blood pressure was controlled with labetalol +gtt. at time of transfer, she denied cp and sob. ces were +flat. she was started on her home bp regimen of oral labetalol +on [**2142-7-15**], and nifedipine/hydralazine/aliskerin soon after +admission. pt was also continued on her hd regimen for esrd, +for volume control. +. +2. angioedema - pt developed facial swelling and shortness of +breath while on medical floor. she was taken to icu and +responded favorably to heliox. patient returned to floor and +has been comfortably breathing since. given history of svc, +venogram was ordered that did not indicate a complete occlusion +of the left brachiocephalic vein, as previously thought, with +help of 22 gauge needle. + +3. cough: pt presented with chronic cough/dyspnea without +fevers. chest ct revealed bilateral infiltrates and +nodularities, noted possibly infectious vs edema. pt was started +on vanc/zosyn given recent hospitalization, brief temp spike, +and pulm infiltrates. abx were stopped after cultures were neg. +at time of transfer, pts dyspnea was largely resolved and these +findings were felt to be more consistent with edema given +hypertensive urgency. +. +4. chronic abdominal pain - pt has had chronic abdominal pain, +which was well controlled at time of transfer. she was continued +on her current outpt pain regimen of po dilaudid, fentanyl +patch, lidoacine patch. her lfts and lipase were wnl. she had no +signs of sbo. +. +5. bacteremia - gpc in pairs and clusters; started on vanco on +[**2142-7-12**]. +. +6. ascites - unclear etiology and new findings for her. pt is +to get workup with liver team as outpatient. her [**date range 2286**] seems +to have slightly improved this finding. her coags were +unremarkable. she was seen by hepatology in house who did not +have any specific recommendations at this time but asked to see +her in follow up as an outpatient. +. +7. esrd on hd - hd satuth,. pt was continued on her hd regimen +while in house. sevelamer was continued as well. +. +8. anemia/pancytopenia - chronic anemia, baseline pancytopenia, +likely [**2-12**] ckd and sle, currently above baseline, though has h/o +gib. pts pancytopenia remained stable; c3 and c4 studies were +performed and it was felt that her sle was not active at this +time. guiac stools were neg. epo was continued at hd. +. +9. h/o gastric ulcer - ppi was continued throughout +hospitalization. +. +10. sle - pt was continued on home regimen of prednisone 4mg po +qdaily. +. +11. h/o svc thrombosis - patients warfarin was discontinued +after discussion with dr. [**last name (stitle) 4883**]. she frequently is outside +of therapeutic range on this medication and given the suspected +problems with medication compliance, it was felt it was safer to +discontinue it altogether. +. +12. seizure disorder - pt was continued on home regimen keppra +1000 mg po 3x/week (tu,th,sa). +. +13. depression - pt was continued on her home celexa. +. + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other ascites; Infection and inflammatory reaction due to other vascular device, implant, and graft; Bacteremia; Other primary cardiomyopathies; Unspecified disease of pericardium; Compression of vein; Systemic lupus erythematosus; Abdominal pain, unspecified site; Other chronic pain; Staphylococcus infection in conditions classified elsewhere and of unspecified site, other staphylococcus; Stridor; Angioneurotic edema, not elsewhere classified; Unspecified accident; Thrombocytopenia, unspecified; Anemia in chronic kidney disease; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Anemia of other chronic disease; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Epilepsy, unspecified, without mention of intractable epilepsy; ; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits]" +109,189332.0,14865,2142-08-30,14864,155726.0,2142-08-16,Discharge summary,"Admission Date: [**2142-8-13**] Discharge Date: [**2142-8-16**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 5123**] +Chief Complaint: +Dyspnea and hypertensive emergency + +Major Surgical or Invasive Procedure: +Hemodialysis + + +History of Present Illness: +Ms. [**Known lastname **] is a 25 year old female with a history of SLE, end +stage renal disease on [**Known lastname 2286**], malignant hypertension, SVC +syndrome, PRES, prior ICH and frequent admissions for +hypertensive emergency now presenting with dyspnea and cough +productive of white sputum x 1-2 days with initial SBP 280s in +ED. Denies F/C, CP, HA, numbness, weakness, visual changes, N/V, +confusion. Reports compliance with meds but has noticed that +clonidine patches have fallen off last 24-48 hours. Her usual +crampy abdominal pain at baseline. Last BM yesterday normal. Pt +last dialyzed Saturday (day prior to admission). Most recently +admitted [**Date range (1) 43608**] with groin pain [**2-12**] HD site, [**Date range (1) 41780**] with +line infection, hypertension, last admitted to MICU [**7-12**] for +hypertensive emergency and discharged [**2142-7-23**]. +. +In ED, initial VS SBP 280/140s T100.3 HR 110 RR 28 SaO2 100%. +She recieved Hydralazine 40mg IV, was maxed out on Nitro drip +and SBP 240s. Also reportedly had fever to 101, CXR with +retrocardiac opacity and received Vancomycin 1g IV and +Levofloxacin 500mg. Has 18g PIV. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD +and now HD 3. Malignant hypertension with baseline SBP's +180's-220's and +history of hypertensive crisis with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**], not further worked up due to frequent +hospitalizations and inability to see in outpatient setting +17. Gastric ulcer +18. PRES + + +Social History: +Home: lives with mother +Occupation: on disability, previously employed with various temp +jobs +EtOH: Denies +Drugs: Denies +Tobacco: Denies + + +Family History: +No history of autoimmune disease + +Physical Exam: +General: A&Ox3. NAD, oriented x3. +HEENT: NC/AT; PERRLA on right, enucleated eye on left; OP clear, +nonerythematous, MMM. +Neck: supple, no LAD, full ROM. +Lungs: CTAB, with decreased BS right base, scant crackles. No +egophony, slight dullness to percussion bases. +CV: Regular, tachy, Prominent heart sounds, S1, S2 +S3, no rubs +appreciated. +Abdomen: Soft, minimally distended, diffuse mild tenderness to +deep palpation, no rebound, guarding. +Ext: WWP, 2+ dp/pt pluses, no clubbing, cyanosis or edema. +Neuro: AAOx3. CN 2-12 intact. 5./5 + + +Pertinent Results: +[**2142-8-13**] 02:15AM BLOOD WBC-6.1# RBC-2.66* Hgb-7.4* Hct-23.8* +MCV-90 MCH-27.9 MCHC-31.1 RDW-19.1* Plt Ct-169# +[**2142-8-13**] 07:52AM BLOOD WBC-4.9 RBC-2.45* Hgb-7.0* Hct-22.0* +MCV-90 MCH-28.7 MCHC-32.0 RDW-20.1* Plt Ct-150 +[**2142-8-14**] 11:44AM BLOOD WBC-3.8* RBC-2.40* Hgb-6.9* Hct-21.7* +MCV-90 MCH-28.8 MCHC-32.0 RDW-20.0* Plt Ct-154 +[**2142-8-13**] 02:15AM BLOOD Neuts-82.4* Bands-0 Lymphs-12.6* +Monos-3.2 Eos-1.6 Baso-0.3 +[**2142-8-13**] 07:52AM BLOOD Neuts-80.6* Lymphs-13.6* Monos-3.9 +Eos-1.7 Baso-0.3 +[**2142-8-14**] 11:44AM BLOOD Neuts-81.3* Lymphs-11.5* Monos-4.4 +Eos-2.4 Baso-0.4 +[**2142-8-13**] 02:15AM BLOOD PT-14.1* PTT-34.0 INR(PT)-1.2* +[**2142-8-13**] 07:52AM BLOOD PT-14.2* PTT-36.1* INR(PT)-1.2* +[**2142-8-14**] 11:44AM BLOOD PT-13.7* PTT-34.7 INR(PT)-1.2* +[**2142-8-13**] 02:15AM BLOOD Glucose-80 UreaN-35* Creat-5.8* Na-137 +K-4.8 Cl-100 HCO3-23 AnGap-19 +[**2142-8-13**] 07:52AM BLOOD Glucose-87 UreaN-37* Creat-6.2* Na-137 +K-4.0 Cl-100 HCO3-24 AnGap-17 +[**2142-8-14**] 11:44AM BLOOD Glucose-131* UreaN-46* Creat-7.1* Na-136 +K-5.5* Cl-102 HCO3-21* AnGap-19 +[**2142-8-13**] 07:52AM BLOOD Calcium-8.5 Phos-5.6* Mg-1.7 +[**2142-8-14**] 11:44AM BLOOD Calcium-8.0* Phos-6.7* Mg-1.7 +[**2142-8-13**] 07:52AM BLOOD Vanco-4.9* +[**2142-8-14**] 11:44AM BLOOD Vanco-5.1* + +Brief Hospital Course: +24F with h/o SLE, ESRD on HD, malignant HTN, h/o SVC syndrome +was admitted to the MICU with dyspnea and hypertensive emergency +with SBP 280s. She has frequent admissions for hypertensive +emergency. See below for specific hospital course on each +problem. +. +# HTN Urgency/Emergency: Patient was admitted directly to the +ICU with shortness of breath and hypertension. One of her +clonidine patches had fallen off and it was likely that this +could have caused some of the elevation in BP. She was started +on a nitro gtt in the ED, but in the MICU she was placed on a +labetolol drip. Lactate on admission was 0.9 and there was no +evidence of new end organ damage. She was restarted on all of +her home meds (except her qhs nifedipine) and transferred to the +floor the next day with SBP in the 160s. During her admission +renal was follwing and recommended that she be given a home +blood pressure cuff. For SBP > 200, she will have hydralazine +100mg PO. She will re-check in 30 mins with instructions to +repeat up to three times before seeking medical attention in the +Emergency room. She was also given dilaudid prn for her pain, +which is a continuation of her outpatient pain regimen. She did +not require hydralazine IV prn on the floor. Prior to discharge +her evening dose of nifedipine was restarted and she recieved +hemodialysis. She remained normotensive during the rest of her +admission and was discharged with stable vital signs. + +# Dyspnea: Patient was admitted with dyspnea, which improved +with resolution of her hypertension. She required supplementary +oxygen intermitantly during the admission but was saturation >92 +% on RA at discharge. There was concern for infection in the ED +and was given as above, likely secondary to pulmonary edema +/- +infection given fever, cough and infiltrate. She was started on +vancomycin in the ED, but that was discontinued and she was not +put on additional antibiotics. She remaine afebrile throughout +the rest of her stay. Blood cultures were negative at time of +discharge. +. +# Fever: Concerning for PNA given complaints of dyspnea and +cough and infiltrate on CXR. Other possible etiologies onclude +line infection given indwelling femoral HD line, however, the +femoral line had been exchanged during previous admission. See +above course in dyspnea section. +. +# Chronic abdominal pain - abdominal pain was well controlled +throughout the admission with PO dilaudid. She was moving her +bowels throughout the stay. Lidocaine patch was also +continued.ontinue neurontin per HD. +. +# ESRD on HD - HD SaTuTh. Sevelamer was continued during the +hospitalization. She recieved hemodialysis on Thursday, [**8-16**] +prior to discharge. +. +# anemia - Pt has chronic anemia, baseline pancytopenia, likely +[**2-12**] CKD and SLE, currently at/slightly below baseline, though +has h/o GIB. HCT 23 here, most recently 22 on discharge [**8-7**]. +We continued EPO per renal and was administered 2 units PRBC's +prior to hemodialysis. +. +# h/o gastric ulcer - continue PPI. +. +# SLE - continue home regimen of prednisone 4mg po qdaily. +. +# h/o SVC thrombosis - Now off anticoagulation secondary to +noncompliance with coumadin +. +# seizure disorder - continue keppra 1000 mg PO 3X/WEEK +(TU,TH,SA). +. +# depression - continue celexa. +. +# FEN: +- low salt diet. +. +# Prophylaxis: heparin SC, PPI. +# Access: PIVx2. +# Code: FULL +# Communication: Patient + + +Medications on Admission: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +2. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QMON (every Monday). +3. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet + +Sustained Release PO DAILY (Daily). +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY +6. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY +7. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly + +Transdermal QMON (every Monday). +9. Sevelamer HCl 400 mg Tablet Sig: One Tablet PO TID +10. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD +11. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID +12. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H 13. +Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for Pain. +14. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO DAYS +(TU,TH,SA). +15. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID +16. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +17. Alprazolam 0.25 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day) as needed for Anxiety. +18. Acetaminophen 325 mg Tablet Sig: One (1) Tablet PO Q6H +(every 6 hours) as needed for fever. +19. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO HS (at bedtime). + + +Discharge Medications: +1. Blood pressure machine +For home blood pressure monitoring three times daily +2. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +3. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every Monday). +4. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QMON (every Monday). +5. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +6. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +7. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +9. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily) as +needed for pain. +10. Sevelamer HCl 400 mg Tablet Sig: One (1) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO QHD (each +hemodialysis). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +15. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO QT, TH +SAT (). +16. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for Constipation. +17. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +18. Alprazolam 0.25 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day) as needed for anxiety. +19. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for fever or pain. +20. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) +Tablet Sustained Release PO DAILY (Daily). +21. Hydralazine 100 mg Tablet Sig: One (1) Tablet PO once as +needed for systolic blood pressure > 200: Take one tablet if +systolic blood pressure > 200. Re-check blood pressure in 30 +mins. Repeat up to 3 times. . +Disp:*30 Tablet(s)* Refills:*3* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Hypertensive Emergency +2. Dyspnea +3. End-Stage Renal Disease (renal failure) + +Secondary Diagnosis: +- Systemic lupus erythematosus +- End Stage Renal Disease on [**Month/Year (2) 2286**] +- Malignant hypertension +- Thrombocytopenia +- Thrombotic events with negative hypercoagulability work-up +- HOCM +- Anemia +- History of left eye enucleation [**2139-4-20**] for fungal infection +- History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +- History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +- Thrombotic microangiopathy +- Obstructive sleep apnea on CPAP +- Left abdominal wall hematoma +- MSSA bacteremia associated with HD line [**Month (only) 956**]-[**2142-3-11**]. + + + +Discharge Condition: +Stable, Vitals stable, asymptommatic + + +Discharge Instructions: +You were admitted to the hospital because of high blood +pressure. You were admitted to the Intensive Care Unit for IV +medications to stabilize your blood pressure while your home +medications were restarted. You the were transferred to the +floor for continued management. You recieved hemodialysis while +in the hospital. + +Changes to medication/management: +You have been given a blood pressure cuff to take your blood +presure at home. If your blood pressure is greater than 200, +take Hydralazine 100 mg by mouth. Recheck blood pressure in 30 +minutes. Repeat up to 3 times. + + +Followup Instructions: +Provider: [**Name10 (NameIs) **],SCHEDULE HEMODIALYSIS UNIT Date/Time:[**2142-8-16**] +12:00 +Provider: [**First Name11 (Name Pattern1) 2890**] [**Initial (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 2226**] +Date/Time:[**2142-8-22**] 8:30 +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 26**] [**Last Name (NamePattern1) 8402**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2142-8-28**] 2:45 + + + +",14,2142-08-13 04:03:00,2142-08-16 18:17:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,DYSPNEA," +24f with h/o sle, esrd on hd, malignant htn, h/o svc syndrome +was admitted to the micu with dyspnea and hypertensive emergency +with sbp 280s. she has frequent admissions for hypertensive +emergency. see below for specific hospital course on each +problem. +. +# htn urgency/emergency: patient was admitted directly to the +icu with shortness of breath and hypertension. one of her +clonidine patches had fallen off and it was likely that this +could have caused some of the elevation in bp. she was started +on a nitro gtt in the ed, but in the micu she was placed on a +labetolol drip. lactate on admission was 0.9 and there was no +evidence of new end organ damage. she was restarted on all of +her home meds (except her qhs nifedipine) and transferred to the +floor the next day with sbp in the 160s. during her admission +renal was follwing and recommended that she be given a home +blood pressure cuff. for sbp > 200, she will have hydralazine +100mg po. she will re-check in 30 mins with instructions to +repeat up to three times before seeking medical attention in the +emergency room. she was also given dilaudid prn for her pain, +which is a continuation of her outpatient pain regimen. she did +not require hydralazine iv prn on the floor. prior to discharge +her evening dose of nifedipine was restarted and she recieved +hemodialysis. she remained normotensive during the rest of her +admission and was discharged with stable vital signs. + +# dyspnea: patient was admitted with dyspnea, which improved +with resolution of her hypertension. she required supplementary +oxygen intermitantly during the admission but was saturation >92 +% on ra at discharge. there was concern for infection in the ed +and was given as above, likely secondary to pulmonary edema +/- +infection given fever, cough and infiltrate. she was started on +vancomycin in the ed, but that was discontinued and she was not +put on additional antibiotics. she remaine afebrile throughout +the rest of her stay. blood cultures were negative at time of +discharge. +. +# fever: concerning for pna given complaints of dyspnea and +cough and infiltrate on cxr. other possible etiologies onclude +line infection given indwelling femoral hd line, however, the +femoral line had been exchanged during previous admission. see +above course in dyspnea section. +. +# chronic abdominal pain - abdominal pain was well controlled +throughout the admission with po dilaudid. she was moving her +bowels throughout the stay. lidocaine patch was also +continued.ontinue neurontin per hd. +. +# esrd on hd - hd satuth. sevelamer was continued during the +hospitalization. she recieved hemodialysis on thursday, [**8-16**] +prior to discharge. +. +# anemia - pt has chronic anemia, baseline pancytopenia, likely +[**2-12**] ckd and sle, currently at/slightly below baseline, though +has h/o gib. hct 23 here, most recently 22 on discharge [**8-7**]. +we continued epo per renal and was administered 2 units prbcs +prior to hemodialysis. +. +# h/o gastric ulcer - continue ppi. +. +# sle - continue home regimen of prednisone 4mg po qdaily. +. +# h/o svc thrombosis - now off anticoagulation secondary to +noncompliance with coumadin +. +# seizure disorder - continue keppra 1000 mg po 3x/week +(tu,th,sa). +. +# depression - continue celexa. +. +# fen: +- low salt diet. +. +# prophylaxis: heparin sc, ppi. +# access: pivx2. +# code: full +# communication: patient + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic glomerulonephritis in diseases classified elsewhere; Other primary cardiomyopathies; Other ascites; Thrombocytopenia, unspecified; Compression of vein; ; Systemic lupus erythematosus; Abdominal pain, unspecified site; Other acute pain; Other chronic pain; Gastric ulcer, unspecified as acute or chronic, without mention of hemorrhage or perforation, without mention of obstruction; Esophageal reflux; Depressive disorder, not elsewhere classified; Anemia in chronic kidney disease; Anemia of other chronic disease; Epilepsy, unspecified, without mention of intractable epilepsy; Other disorders of bone and cartilage; Obstructive sleep apnea (adult)(pediatric); Other specified peripheral vascular diseases; Mild dysplasia of cervix; Noncompliance with renal dialysis; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +109,189332.0,14865,2142-08-30,14859,102024.0,2142-06-05,Discharge summary,"Admission Date: [**2142-5-20**] Discharge Date: [**2142-6-5**] + +Date of Birth: [**2117-8-7**] Sex: F + +Service: MEDICINE + +Allergies: +Penicillins / Percocet / Morphine + +Attending:[**First Name3 (LF) 3705**] +Chief Complaint: +abdominal pain, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Ms [**Known lastname **] is a 24 yo F with lupus since age 16, with ESRD on HD, +malignant HTN, history of SVC syndrome, and history of Posterior +Reversible Encephalopathy Syndrome (PRES) and intracerebral +hemorrhage, who has had multiple recent admissions [**Date range (1) 43604**], +[**Date range (1) 17717**], [**Date range (1) **], [**4-26**], [**Date range (1) 42063**], [**Date range (1) 43605**] mostly for +hypertension, but most recently for diarrhea in addition to +hypertension. +. +In the ED, vitals were 98 90 102/65 20 98% RA. She was +complaining of abdominal pain X 3 hours, more severe than usual +[**7-20**], no N/V/D. She received dilaudid 4 mg PO X 3, zofran 8mg +IV, hyperkalemia 6.2=>5.3 w/ Kayexalate. Initially, she was felt +stable for floor; however, BP rose during ED course to SBP 270. +She then received hydral 50 PO X 1, home aliskeren, labetalol +1000 PO X 1, 20 IV hydral X 2, labetalol 100 Iv X 1, nicardipine +2.5 mg IV X 1 and started on nicardipine gtt. +. +Upon arrival to the floor, she complains of severe abd pain +which started earlier today, it is sharp all over her abd and +constant. It feels different from her usual abd pain, although +she is not able to characterize it more. She has been having +some nausea and bilious emesis X 1 earlier today. She has been +having some mild diarrhea 2-3 episodes of loose, greenish stools +for the past few weeks. She denies any chest pain, headache, +vision changes. She was not able to take all of the medications +due to her GI distress. +. +While in the MICU she was weaned off a nicardipine drip and her +diarrhea resolved. Her BP remained WNL while on her home regimen +and she was transferred to the floor in stable condition. Last +HD was [**2142-5-21**]. + + +Past Medical History: +1. Systemic lupus erythematosus since age 16 complicated by +uveitis and end stage renal disease since [**2135**]. +-s/p treatment with cyclophosphamide and mycophenolate and now +maintained on prednisone +2. CKD/ESRD: Diagnosed in [**2135**] and has previously been on PD and +now HD with intermittent refusal of dialysis, currently only +agrees to be dialyzed one time/wk +3. Malignant hypertension and history of hypertensive crisis +with seizures. +4. Thrombocytopenia +5. Thrombotic events with negative hypercoagulability work-up +- SVC thrombosis ([**2139**]); related to a catheter +- Negative lupus anticoagulant ([**4-/2138**], [**8-/2138**], [**9-/2140**]) +- Negative anticardiolipin antibodies IgG and IgM x4 ([**2137**]-[**2140**]) + +- Negative Beta-2 glycoprotein antibody ([**4-/2138**], [**8-/2140**]) +6. HOCM: Last noted on echo [**8-17**] +7. Anemia +8. History of left eye enucleation [**2139-4-20**] for fungal infection + +9. History of vaginal bleeding [**2139**] lasting 2 months s/p +DepoProvera injection requiring transfusion +10. History of Coag negative Staph bacteremia and HD line +infection - [**6-16**] and [**5-17**] +11. Thrombotic microangiopathy +12. Obstructive sleep apnea on CPAP +13. Left abdominal wall hematoma +14. MSSA bacteremia associated with HD line [**Month (only) 956**]-[**Month (only) 958**], +[**2142**]. +15. Pericardial effusion +16. CIN I noted in [**2139**] and [**2142-4-12**], not further worked up due to +frequent hospitalizations and inability to see in outpatient +setting - has appt scheduled with gyn on [**5-25**] +17. History of two intraparenchymal hemorrhages that were +thought +due to the posterior reversible leukoencephalopathy syndrome, +associated with LE paresis in [**2140**] which has resolved + + +Social History: +Denies any substance abuse (EtOH, tobacco, illicits). She lives +with her mother and brother. On disability for multiple medical +problems. + + +Family History: +No known autoimmune disease but there is a history of +cardiovascular disease and cerebrovascular accident in her +grandfather. + +Physical Exam: +100/63 81 18 100RA +GENERAL: Pleasant, thin young female sitting in the bed in NAD +watching TV. +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. s/p left eye enucleation. PERRLA/EOMI. MMM. OP +clear. Neck Supple, No LAD. +CARDIAC: RRR. 4/6 systolic murmur heard best at the RUSB. +LUNGS: Breathing comfortably, CTAB, good air movement +biaterally. +ABDOMEN: + BS, soft ND, tenderness to palpation in her LUQ. No +rebound or guarding. +EXTREMITIES: No edema. Right femoral HD line nontender, +nonerythematous. +SKIN: Several subcutaneous cysts of different sizes 1 - 3 cm +scattered along her lower extremities. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Preserved +sensation to light touch throughout. 5/5 strength in her upper +and lower extremities +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2142-5-20**] 09:14PM LACTATE-0.9 +[**2142-5-20**] 09:13PM WBC-6.8 RBC-3.65* HGB-10.7* HCT-33.7* MCV-93 +MCH-29.2 MCHC-31.6 RDW-18.8* +[**2142-5-20**] 09:13PM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-1+ POLYCHROM-OCCASIONAL OVALOCYT-1+ +TEARDROP-OCCASIONAL +[**2142-5-20**] 09:13PM PLT COUNT-145* +[**2142-5-20**] 08:55PM GLUCOSE-98 UREA N-44* CREAT-7.7* SODIUM-137 +POTASSIUM-6.3* CHLORIDE-102 TOTAL CO2-20* ANION GAP-21* +[**2142-5-20**] 08:55PM CALCIUM-9.9 PHOSPHATE-5.8* MAGNESIUM-2.1 +[**2142-5-20**] 08:55PM ASA-NEG ACETMNPHN-NEG bnzodzpn-NEG +barbitrt-NEG tricyclic-NEG +[**2142-5-20**] 08:55PM WBC-7.0 RBC-3.69* HGB-11.1* HCT-34.2* MCV-93 +MCH-30.2 MCHC-32.5 RDW-19.2* +[**2142-5-20**] 08:55PM PLT COUNT-126* +[**2142-5-20**] 08:55PM PT-14.1* PTT-32.4 INR(PT)-1.2* +[**2142-5-20**] 07:40AM ALT(SGPT)-18 AST(SGOT)-55* ALK PHOS-118* TOT +BILI-0.4 +[**2142-5-20**] 07:40AM LIPASE-58 + +Brief Hospital Course: +KUB: SBO + +Head CT: (prelim read from radiology). unchanged from prior head +CT, no intracranial hemorrhage + +EKG: NSR, right axis, LVH, nl intervals, ST elevations V2-3 +(old), TW inversion V6 (new) compared to prior EKG [**5-15**]. + +CT CHEST/ABD: Preliminary Read +Normal aorta without dissection or acute abnormality. No PE. +Stable trace +ascites and small right pleural effusion. Unchanged small +pulmonary nodules +and lymphadenopathy in the chest. No acute abnormalities in the +abdomen to +explain epigastric pain. + +EGD: Ulcer at GE junction. + +# Hypertensive urgency: This is a chronic issue related to ESRD. +Head CT was negative for intracranial bleed. Weaned off +Nicardipine gtt and BP well controlled on home regimen. +Continued her home regimen of: Aliskiren 150 mg po bid, +Clonidine 0.4 mg/24 hr Patch Weekly, Labetalol 1000 mg po TID, +Nifedipine 60 mg Tablet Sustained Release QPM and 90 mg Tablet +Sustained Release QAM, Hydralazine 100 mg PO Q8H. When BPs were +lower (see below) patient's BP meds were held occasionally, but +as she was transfused and the BPs started to trend back up the +meds were re-initiated. She then developed hypotension in the +setting of poor PO intake during her SBO. BP meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# Abdominal pain/UGIB: The patient has chronic abdominal pain +with previous negative workups. At first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. GI was c/s re: abd pain and rec +CTA-abdomen to eval for mesenteric ischemia vs. partial SBO, +however with ESRD did not initially want to get CTA so KUB was +ordered. This showed no SBO. They recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +LFTs were at baseline. The patient then developed a different +type of pain associated with her incision site. Pain service was +consulted and did a bupivicaine injection at the site which did +help. They will continue to follow her. She then developed a +third type of pain associated with a burning sensation in her +chest. EKG was unchanged from prior. A few hours later she had 3 +episodes of coffee-ground emesis. She was placed on IV PPI and +transfused two units of blood. Afterward the pain resolved and +her hct remained stable. GI felt that the patient would need +general anesthesia in order to undergo an EGD which showed an +ulcer at the GE junction. She was started on empiric treatment +for H. Pylori and serologies were sent which came back negative +so the antibiotics were stopped. Her pain was controlled with +her outpatient regimen of PO dilaudid. She will follow up with +Dr. [**Last Name (STitle) **] in [**6-18**] weeks to have another EGD under MAC to see if +there has been resolution of the ulcer. + +# SBO: Continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine PRN +howeve she continued to have n/v. A KUB was done which showed an +SBO. Surgery was consulted, NGT was placed, she was made NPO and +serial abdominal exams were done. Eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. Fever: On hospital day #6 she spiked a fever to 101. Blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. She had an episode of hypoxia with this and was +transferred to the ICU. In the ICU LP was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. Broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. She improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. Seizure: This occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. Neurology was consulted +and felt she should be continued on keppra indefinitely. EEG was +non-revealing. She should be continued on keppra 1gm with +dialysis three times weekly. + +# ESRD on HD: Hyperkalemia resolved with kayexalate. Underwent +dialysis on normal schedule. + +# SLE: She was continued on prednisone 4mg daily. With multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. C3, c4 were equivocal for active lupus flare, and +[**Doctor First Name **] was positive, as would be expected in lupus. + +# Anemia: Has anemia of chronic renal disease and her Hct was +high on admission and epo was held per renal. However, her Hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie SBP 120) and she developed coffee ground +emesis so she was transfused 2 units. Afterward her Hct was +stable at 25. She was also re-started on EPO per renal for her +chronic anemia. Hemolysis labs were negative. + +# History of thrombotic events/SVC syndrome: She is +anticoagulated with warfarin as an outpatient. Previous +documentation in OMR states she does not need to be bridged +while subtherapeutic. Continued coumadin 4 mg po daily however +INR became supratherapeutic and the coumadin was then held. She +was started on heparin gtt while awaiting EGD. After EGD the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her INR was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when INR [**2-13**] +at dialysis. + +# OSA: She is on CPAP at a setting of 7 as an outpatient. +Continued CPAP + +#. CIN1: On last pap had CIN1. OB/GYN service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. Will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# RLL nodule: A new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal CT. +This should be reassessed in 3 months. + +# ACCESS: PIV, right groin HD line +# CODE: Full code + + +Medications on Admission: +1. Aliskiren 150 mg PO bid +2. Citalopram 20 mg PO DAILY +3. Clonidine 0.2 mg/24 hr Patch Weekly QSAT +4. Hydromorphone 2 mg 1-2 Tablets PO Q4H +5. Fentanyl 25 mcg/hr Patch 72 hr +6. Gabapentin 300 mg PO TID +7. Hydralazine 100 mg PO Q8H +8. Hydralazine 100 mg PO BID PRn fro SBP> 180. +9. Prednisone 4 mg PO DAILY +10. Pantoprazole 40 mg PO Q24H +11. Labetalol 1000 mg PO TID +12. Nifedipine 90 mg PO QAM +13. Nifedipine 60 mg PO QHS +14. Warfarin 3 mg PO Once Daily +15. Lidocaine 5 %(700 mg/patch) Topical once a day. +16. Nifedipine 90 mg PO once a day as needed for for SBP +persistently above 200. + +Discharge Medications: +1. Nifedipine 90 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO QAM (once a day (in the morning)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +2. Nifedipine 30 mg Tablet Sustained Release Sig: Two (2) Tablet +Sustained Release PO QHS (once a day (at bedtime)). +Disp:*30 Tablet Sustained Release(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Aliskiren 150 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Fentanyl 25 mcg/hr Patch 72 hr Sig: One (1) Patch 72 hr +Transdermal Q72H (every 72 hours). +7. Prednisone 1 mg Tablet Sig: Four (4) Tablet PO DAILY (Daily). + +8. Clonidine 0.1 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +9. Clonidine 0.3 mg/24 hr Patch Weekly Sig: One (1) Patch Weekly +Transdermal QSAT (every Saturday). +10. Sevelamer HCl 400 mg Tablet Sig: Four (4) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +11. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +12. Labetalol 200 mg Tablet Sig: Five (5) Tablet PO TID (3 times +a day). +13. Hydralazine 50 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +14. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours) for +30 days. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +16. LeVETiracetam 1,000 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +Disp:*90 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +UGIB- Ulcer at GE junction +Hypertensive Emergency +Anemia +ESRD on HD +SBO + + +Discharge Condition: +The patient was afebrile and hemodynamically stable prior to +discharge. + + +Discharge Instructions: +You were admitted to the hospital with abdominal pain. You had +an injection of lidocaine to help the pain around your surgery +sites. You then had some blood in your vomit. You were treated +for a bleed in your stomach with a blood transfusion and +medications. You stopped bleeding and felt better. You had a +scope of your abdomen that showed an ulcer. You were treated +with medications for this and need to have another scope of your +abdomen in 6 weeks. You also had high blood pressures while you +were here because you could not take your medicines with your +nausea and vomiting. Once you were on your home medicines your +blood pressure was better. + +Medication Changes: +CHANGE: Pantoprazole to 40mg TWICE daily + +Please call your PCP or come to the emergency room if you have +fevers, chills, worsening abdominal pain, nausea, vomiting, +blood in your vomit, blood in your stools, black/tarry stools or +any other concerning symptoms. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] (gastroenterology) in [**6-18**] +weeks for an EGD to re-look at your ulcer. + +Please follow up with the OB/[**Hospital **] clinic for a colposcopy on +Wednesday [**2142-8-8**] at 3:15pm in the [**Hospital Ward Name 23**] Building on the [**Location (un) **]. Their number is [**Telephone/Fax (1) 2664**]. + +Please follow up with Dr.[**Name (NI) **] at [**Hospital6 733**] in +the Shapria building on the [**Location (un) **] on [**2142-6-27**] at 2:00pm. + + + +Completed by:[**2142-6-6**]",86,2142-05-20 12:59:00,2142-06-05 16:18:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ABDOMINAL PAIN," +kub: sbo + +head ct: (prelim read from radiology). unchanged from prior head +ct, no intracranial hemorrhage + +ekg: nsr, right axis, lvh, nl intervals, st elevations v2-3 +(old), tw inversion v6 (new) compared to prior ekg [**5-15**]. + +ct chest/abd: preliminary read +normal aorta without dissection or acute abnormality. no pe. +stable trace +ascites and small right pleural effusion. unchanged small +pulmonary nodules +and lymphadenopathy in the chest. no acute abnormalities in the +abdomen to +explain epigastric pain. + +egd: ulcer at ge junction. + +# hypertensive urgency: this is a chronic issue related to esrd. +head ct was negative for intracranial bleed. weaned off +nicardipine gtt and bp well controlled on home regimen. +continued her home regimen of: aliskiren 150 mg po bid, +clonidine 0.4 mg/24 hr patch weekly, labetalol 1000 mg po tid, +nifedipine 60 mg tablet sustained release qpm and 90 mg tablet +sustained release qam, hydralazine 100 mg po q8h. when bps were +lower (see below) patients bp meds were held occasionally, but +as she was transfused and the bps started to trend back up the +meds were re-initiated. she then developed hypotension in the +setting of poor po intake during her sbo. bp meds were held and +then re-initiated as the pressure came back up once she was able +to eat. + +# abdominal pain/ugib: the patient has chronic abdominal pain +with previous negative workups. at first the pain resolved and +she was continued on her outpatient regimen of: 2-4 mg po +dilaudid q4 h as needed. gi was c/s re: abd pain and rec +cta-abdomen to eval for mesenteric ischemia vs. partial sbo, +however with esrd did not initially want to get cta so kub was +ordered. this showed no sbo. they recommended checking urine +porphyrobilinogen and serum lead levels which were negative and +lfts were at baseline. the patient then developed a different +type of pain associated with her incision site. pain service was +consulted and did a bupivicaine injection at the site which did +help. they will continue to follow her. she then developed a +third type of pain associated with a burning sensation in her +chest. ekg was unchanged from prior. a few hours later she had 3 +episodes of coffee-ground emesis. she was placed on iv ppi and +transfused two units of blood. afterward the pain resolved and +her hct remained stable. gi felt that the patient would need +general anesthesia in order to undergo an egd which showed an +ulcer at the ge junction. she was started on empiric treatment +for h. pylori and serologies were sent which came back negative +so the antibiotics were stopped. her pain was controlled with +her outpatient regimen of po dilaudid. she will follow up with +dr. [**last name (stitle) **] in [**6-18**] weeks to have another egd under mac to see if +there has been resolution of the ulcer. + +# sbo: continued to be nauseous and vomited intermittently. she +was started on reglan and continued on zofran and compazine prn +howeve she continued to have n/v. a kub was done which showed an +sbo. surgery was consulted, ngt was placed, she was made npo and +serial abdominal exams were done. eventually she was able to +transition to clear diet and then tolerated a regular diet +without pain or vomiting. + +#. fever: on hospital day #6 she spiked a fever to 101. blood +and urine cultures were sent and a cxr were negative, however +she then had a seizure and in the post-ictal state aspirated +after vomiting. she had an episode of hypoxia with this and was +transferred to the icu. in the icu lp was attempted to rule out +meningitis as a possible cause of a seizure but this was +unsuccessful. broad spectrum antibiotics were initiated (vanc +ctx) at meningeal dosing. she improved over the next few days +and antibiotics were discontinued because the suspicion for a +bacterial meningitis was low. + +#. seizure: this occured in the setting of fever, hypotension, +and initiation of reglan for vomiting. neurology was consulted +and felt she should be continued on keppra indefinitely. eeg was +non-revealing. she should be continued on keppra 1gm with +dialysis three times weekly. + +# esrd on hd: hyperkalemia resolved with kayexalate. underwent +dialysis on normal schedule. + +# sle: she was continued on prednisone 4mg daily. with multiple +abdominal symptoms it was thought she may have lupus flare in +the abdomen. c3, c4 were equivocal for active lupus flare, and +[**doctor first name **] was positive, as would be expected in lupus. + +# anemia: has anemia of chronic renal disease and her hct was +high on admission and epo was held per renal. however, her hct +trended all the way down to 20 and she was borderline +hypotensive for her (ie sbp 120) and she developed coffee ground +emesis so she was transfused 2 units. afterward her hct was +stable at 25. she was also re-started on epo per renal for her +chronic anemia. hemolysis labs were negative. + +# history of thrombotic events/svc syndrome: she is +anticoagulated with warfarin as an outpatient. previous +documentation in omr states she does not need to be bridged +while subtherapeutic. continued coumadin 4 mg po daily however +inr became supratherapeutic and the coumadin was then held. she +was started on heparin gtt while awaiting egd. after egd the +coumadin was re-started at 3mg daily however, in setting of poor +po intake her inr was supratherapeutic - likely [**2-12**] nutritional +deficiency of vitamin k. coumadin will be restarted when inr [**2-13**] +at dialysis. + +# osa: she is on cpap at a setting of 7 as an outpatient. +continued cpap + +#. cin1: on last pap had cin1. ob/gyn service was called re: +doing colposcopy in hospital as patient rarely makes o/p +appointments, hwoever they do not do this procedure in hospital +especially because it does not have to be done emergently - just +within one year. will need outpatient colposcopy at some point +in next few months as they do not do this procedure in the +hospital. + +# rll nodule: a new 10 x 5 mm nodularity was found incidentally +within the right lower lobe of the lung on an abdominal ct. +this should be reassessed in 3 months. + +# access: piv, right groin hd line +# code: full code + + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease] +SECONDARY: [End stage renal disease; Chronic or unspecified gastric ulcer with hemorrhage, without mention of obstruction; Acute posthemorrhagic anemia; Unspecified intestinal obstruction; Other primary cardiomyopathies; Unspecified disease of pericardium; Systemic lupus erythematosus; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Disorders of phosphorus metabolism; Hypotension, unspecified; Hyperpotassemia; Mononeuritis of unspecified site; Anemia of other chronic disease; Abdominal pain, left lower quadrant; Other chronic pain; Thrombocytopenia, unspecified; Diaphragmatic hernia without mention of obstruction or gangrene; Other specified peripheral vascular diseases; Carrier or suspected carrier of Methicillin resistant Staphylococcus aureus; Noncompliance with renal dialysis; Renal dialysis status; Long-term (current) use of anticoagulants; Personal history of noncompliance with medical treatment, presenting hazards to health]" +2208,144187.0,23610,2190-09-28,23609,162248.0,2190-08-24,Discharge summary,"Admission Date: [**2190-8-18**] Discharge Date: [**2190-8-24**] + +Date of Birth: [**2120-10-4**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Hydralazine + +Attending:[**First Name3 (LF) 13541**] +Chief Complaint: +Vomiting + +Major Surgical or Invasive Procedure: +1. Intraosseous access obtained. +2. Right internal jugular central venous catheter placed. +3. Left PICC placed. +4. Endotracheal intubation + +History of Present Illness: +69 year old male with h/o CVA and baseline non-communicative, +aspiration pna, hydrocephalus s/p VP shunt who was brought in +from NH by son for nausea and vomiting. Also noted to have +increased yellow secretions. Per sone, his father has been +pulling at his g-tube for past few days; unable to communicate +though so son unclear whether it was painful. Did not know +whether tube feeds have been a problem. Pt reports MS [**First Name (Titles) **] [**Last Name (Titles) 10252**]e; unchanged. + +On arrival to [**Name (NI) **], pt non-communicative (but at baseline), Fever +102. HR 120s, SBP 120. CXR was done which was wnl. WBC 22. +Lactate 1.9. CT head was done given h/o hydrocephalus and new +onset vomiting. CT was concerning for enlarged 3rd ventricle +thus neurosurgery evaluated pt and felt unlikely to represent +signficant change. CT Abd/Pelvis done which showed bibasilar +opacities c/w aspiration pneumonia. Pt given Vanc/Levo/Flagyl +for aspiration pna. + +In addition, central access was attempted x3; unsuccess femoral +line attempts on both R/L and subclavian secondary to return of +arterial blood; thus intraosseous access obtained. Also of note, +during the multiple line attemps, pt became increasing +tachycardic, hypotensive, vomiting with ?aspiration. NGT placed +with coffee-ground return. Pt hydrated with 4L NS. BP remained +stable however was tachycardic to 120s persistantly despite +fluids. 2 PIVs subsequently obtained. + +Of note, pt was admitted [**Date range (1) 39587**] with fever,cough and intially +tx for aspiration pna but subsequently found to have C.diff and +Proteus UTI; d/c'd with 10D meropenem and 14D flagyl. He was +then readmitted [**Date range (1) 27450**] for recurrent c.diff, VRE UTI and +yeast UTI and d/c'd on flagyl, fluconazole and tetracycline. Of +note, all c.diff toxin cultures from [**Month (only) **] were negative. + +Past Medical History: +Alzheimer's dementia +Bipolar disorder +PVD +DM type II +Hydrocephalus s/p VP shunt (son says it was placed 3-5 years ago + +at [**Hospital3 **] with no revisions, unknown cause of +hydrocephalus) +H/o subdural hemorrhages (unknown if before or after shunt +placed) +Hearing loss with hearing aids +Cataracts +Hypertension +Hypercholesterolemia +h/o SIADH with fluid restriction of 1L per day +h/o aspiration PNAs +s/p recent CVA ([**2190-6-3**]) +Recent C. diff infection +h/o VRE UTI + + +Social History: +Resides in NH. Used to work as an accountant, 100 pack year +smoking history, He is nonverbal at baseline with a PEG tube. He +is dependent on others for ADLs. + +Family History: +Type 2 diabetes mellitus, Alzheimer's and Bipolar Disease. + + +Physical Exam: +T:98 BP: 123/61 HR: 129 R 20 O2Sats 98% +on Vent support +Gen: Intubated, sedated, NG tube with some coffee-grounds. VP +shunt - scalp site easily compressible +HEENT: Pupils: 6-4 mm B/L +Neck: Supple. +Lungs: Coarse crackles B/L. +Cardiac: Heart sounds are irregularly irregular, with a +pansystolic murmur radiating to the axilla. +Abd: PEG site clean. Foley in situ. Hypoactive bowel sounds +Extrem: Cold peripheries. +Neuro: +Intubated and sedated, therefore could not be assessed, +therefore, mental status could not be assessed. +Pupils equally round and reactive to light. + + +Pertinent Results: +[**2190-8-18**] 04:15PM GLUCOSE-178* UREA N-82* CREAT-0.7 SODIUM-142 +POTASSIUM-5.4* CHLORIDE-100 TOTAL CO2-26 ANION GAP-21* +[**2190-8-24**] 06:15AM Glucose-216* UreaN-10 Creat-0.3* Na-139 K-5.0 +Cl-107 HCO3-22 AnGap-15 +[**2190-8-18**] 04:15PM CALCIUM-11.4* PHOSPHATE-4.9* MAGNESIUM-2.8* +[**2190-8-18**] 04:15PM WBC-22.8*# RBC-5.03# HGB-13.9*# HCT-41.9 +MCV-83# MCH-27.7 MCHC-33.3 RDW-16.0* PLTS: 422 +[**2190-8-18**] 04:15PM NEUTS-80.4* LYMPHS-13.9* MONOS-4.9 EOS-0.3 +BASOS-0.5 +WBC: 22.8 -> 11.0 +HCT: 41.9 ([**8-18**]) -> 23.1 ([**8-22**]) -> 31.9 ([**8-24**], after 2 units +RBCs) +Lactate: 1.9 +INR: 1.3 -> 1.7 -> 1.3 + +Imaging: +CT ABDOMEN/PELVIS ([**8-18**]): +IMPRESSION: +1. Extensive tree-in-[**Male First Name (un) 239**] opacities at the lung bases are +suggestive of aspiration. +2. Poorly defined areas of hypodensity in the left kidney are +new from a prior study from [**2188**] and raise concern for +infectious or ischemic process. +3. No evidence of acute bowel process. +4. VP shunt catheter tip in the right hemiabdomen appearing +unremarkable. + +CT Head ([**8-18**]): +Continued evolution of blood products of left MCA territory +infarction. No midline shift. Enlarged 3rd ventricle. Persistent +dilatation of the lateral ventricles. These findings may be +chronic but correlation with signs of increased cranial pressure +recommended. + +Renal U/S ([**8-19**]): +IMPRESSION: +No definite son[**Name (NI) 493**] correlates identified for bilateral +renal +hypodensities seen on previous CT, with no solid masses +identified. The +nephrographic abnormalities on recent CT are suspicious for +infectious or +ischemic process and their lack of visualization may relate to +limitations of this study. + +CXR ([**8-21**]): +FINDINGS: Comparison with study of [**8-20**], there are lower lung +volumes. There is still some right infrahilar and left +suprahilar opacification consistent with aspiration. However, +some of this may also reflect crowding of vessels due to poor +inspiration. + +Right UE U/S ([**8-23**]): +IMPRESSION: No DVT in the right upper extremity. Right cephalic +vein was not definitely identified. + +Brief Hospital Course: +# Aspiration pneumonia +Initially febrile with leukocytosis. Patient was intubated in +the ED for concerns regarding airway protection and continued +vomiting. He also received Vanc/Levo/ Flagyl in the ED. Vent +settings were gradually weaned and he was easily extubated on +[**2190-8-20**]. He had sputum cultures sent, which grew MRSA and +Klebsiella pneumonia. He was on aspiration precautions and +treated with a regimen of vanco and ceftriaxone. However, the +ceftriaxone was switched to meropenem given ESBL Klebsiella in +the urine. He will complete a 10d course of vanco and a 14d +course of meropenem. At time of discharge, his fevers and +leukocytosis have resolved, he continues to have SpO2 in the +upper 90s on room air, and his secretions have improved. + +# Hypovolemia +Labs initially suggestive of significant volume depletion with +hypotension, increased calcium, BUN, hematocrit. He is unable to +independently take POs, and had been vomiting. He received 4L IV +NS in the ED via intraosseous line as no peripherals or central +lines could be placed. Also, he was tachycardic, likely both +from volume depletion and holding his antihypertensives due to +hypotension. Once in the MICU, a R IJ TLC was placed. His blood +pressure and heart rate normalized with volume resuscitation, +and his TLC was d/c'd once PICC access was obtained with IR +assistance. + +# Hypertension +Occurred a few days after his hypovolemia and hypotension were +corrected. Likely due to a rebound effect from being off his +home antihypertensives, especially clonidine. The hypertension +resolved after these medications were resumed, albeit at lower +doses and with clonidine given PO. His EKG showed stable LVH and +new TWI in the anteroseptal leads. This is nonspecific, but due +to the possibility of ischemia, cardiac markers were checked and +were not elevated when compared to his baseline. He was also +continued on his home aspirin. +- Please note that he does NOT currently have a clonidine patch. +This was written in the discharge medications, but can be placed +at the ECF. +- Also, his other antihypertensives are at lower doses - please +titrate to his prior regimen as tolerated. + +# N/V +CT showed no acute abdominal pathology. LFTs WNL. Neurosurgery +was consulted initially for concern of worsening ICP in a +patient with a VP shunt, but felt his head CT was not suggestive +of this. [**Name (NI) **] son felt that his mental status was at +baseline. Following extubation, TFs were restarted gradually +with high residuals, so he was started on reglan for presumed +diabetic gastroparesis as the cause of his vomiting. There may +have also been contribution by his UTI, as this has caused these +symptoms in him previously. + +# UTI. Urine growing Proteus, ESBL Klebsiella, both sensitive to +meropenem. His inital ceftriaxone and bactrim were switched to +meropenem 500mg q6h and will be continued to complete a 14 day +course. His foley was d/c'd and replaced by a condom cath. + +# Anemia +Hematocrit initially 41.9 due to hemoconcentration from +dehydration. It gradually trended down to a nadir of 23.1. He +received 2 units pRBCs, and it remained stable around 32 +subsequently. No coffee grounds were noted since the ED, and his +stool was guaiac negative x2. He was started on lansoprazole. + +# FEN +Initially had to hold TF for high residuals, but after reglan +was started, we were able to advance him to a goal of 45ml/hr, +which was well tolerated. He received 35 units glargine qhs due +to initial decreased enteral intake, but this was increased to +60 units glargine qhs at discharge as he is at goal with TFs and +having glucose levels upper 200s, lower 300s. +- Please uptitrate the glargine to his prior regimen (listed as +78 units qhs) as tolerated. + +# R UE swelling +Doppler U/S performed and showed no evidence of DVT. + +# Dispo +His other chronic issues remained stable and were treated as +previously. He will be discharged back to the extended care +facility from which he was admitted. + +Medications on Admission: +Heparin (Porcine) 5,000 unit/mL Solution [**Name (NI) **]: 5000 (5000) +units Injection TID (3 times a day). +Chlorhexidine Gluconate 0.12 % Mouthwash [**Name (NI) **]: Fifteen (15) ML +Mucous membrane [**Hospital1 **] (2 times a day). +Clonidine 0.3 mg/24 hr Patch Weekly [**Hospital1 **]: One (1) Patch Weekly +Transdermal QTHUR (every Thursday). +Metoprolol Tartrate 75 mg Tablet [**Hospital1 **]: One (1) Tablet PO BID +(2 times a day). +Lisinopril 40 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY (Daily). +Aspirin 325 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY (Daily). +Simvastatin 40 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY +(Daily). +Levothyroxine 25 mcg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY +(Daily). +Docusate Sodium 50 mg/5 mL Liquid [**Hospital1 **]: One Hundred (100) mg +PO BID (2 times a day). +Bisacodyl 10 mg Suppository [**Hospital1 **]: One (1) Suppository Rectal +DAILY (Daily) as needed for constipation: Give if no bowel +movement within the last 24 hours. +Lantus 100 unit/mL Solution [**Hospital1 **]: Seventy-eight (78) units +Subcutaneous at bedtime. +Insulin Regular Human 100 unit/mL Solution [**Hospital1 **]: As directed +Injection every six (6) hours: Insulin sliding scale. +Acetaminophen 650mg q4h PRN +Furosemide 40mg PO daily +MVI 1 tab daily + +Discharge Medications: +1. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) [**Hospital1 **]: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +2. Heparin (Porcine) 5,000 unit/mL Solution [**Hospital1 **]: One (1) +Injection TID (3 times a day). +3. Aspirin 325 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY (Daily). +4. Simvastatin 40 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY +(Daily). +5. Docusate Sodium 100 mg Capsule [**Hospital1 **]: One (1) Capsule PO BID (2 +times a day) as needed. +6. Acetaminophen 325 mg Tablet [**Hospital1 **]: Two (2) Tablet PO every four +(4) hours as needed for fever or pain: Max 4g/day. +7. Levothyroxine 25 mcg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY +(Daily). +8. Metoprolol Tartrate 25 mg Tablet [**Hospital1 **]: One (1) Tablet PO three +times a day: Hold for SBP < 100, HR < 60. +9. Metoclopramide 10 mg Tablet [**Hospital1 **]: One (1) Tablet PO QID (4 +times a day). +10. Insulin Glargine 100 unit/mL Solution [**Hospital1 **]: Sixty (60) units +Subcutaneous at bedtime: plus sliding scale, see attached. +11. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization [**Hospital1 **]: One (1) Inhalation Q6H (every 6 hours) as +needed for wheezing on exam. +12. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] DAILY (Daily). +13. Vancomycin in Dextrose 1 gram/200 mL Piggyback [**Last Name (STitle) **]: One (1) +Intravenous Q 12H (Every 12 Hours) for 4 days: 10 day course to +finish on [**2190-8-27**]. +14. Clonidine 0.3 mg/24 hr Patch Weekly [**Date Range **]: One (1) Patch +Weekly Transdermal Q WEDNESDAY. +15. Heparin Flush (10 units/ml) 2 mL IV PRN line flush +PICC, heparin dependent: Flush with 10mL Normal Saline followed +by Heparin as above daily and PRN per lumen. +16. Meropenem 500 mg Recon Soln [**Date Range **]: One (1) Recon Soln +Intravenous Q6H (every 6 hours) for 13 days: 14 day course to +complete on [**2190-9-5**]. +17. Ondansetron 4 mg Tablet, Rapid Dissolve [**Date Range **]: One (1) Tablet, +Rapid Dissolve PO every eight (8) hours as needed for nausea. +18. Lisinopril 10 mg Tablet [**Date Range **]: One (1) Tablet PO once a day: +hold for SBP < 95. +19. insulin +see attached sliding scale for regular insulin + +Discharge Disposition: +Extended Care + +Facility: +Roscommon + +Discharge Diagnosis: +Primary: +Aspiration pneumonia +Complicated cystitis. + +Secondary diagnoses: +Diabetes mellitus type 2, controlled, with complications +Peripheral vascular disease +Hypertension +Prior cerebrovascular accident +Chronic anemia +Hydrocephalus with ventriculoperitoneal shunt + + +Discharge Condition: +Stable. + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] with vomiting. This was likely +because the tube feeds were passing through your bowels very +slowly, perhaps due to diabetes. Some of the vomit entered your +lungs and lead to a pneumonia. We also found a bladder +infection, and treated both infections with IV antibiotics. Your +blood pressure was initially low, which improved with fluids. It +became high later, but improved when we restarted your +outpatient medications. We also gave you 2 units of blood +because your red blood cell level was low. We will discharge you +back to your extended care facility. + +Please take all medications as prescribed and go to all follow +up appointments. We started another medication, reglan, to help +prevent your stomach from slowing down. We also started +lansoprazole due to concern about stomach irritation. + +If you experience any nausea, vomiting, difficulty breathing, +fevers, chills, increased sputum, blood in the vomit or stool, +or any other concerning symptoms, please seek medical attention +or come to the emergency room immediately. + +Followup Instructions: +Please follow up with your primary care provider at [**Name9 (PRE) 10246**] +within 1-2 weeks. + + + [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] MD [**MD Number(2) 13546**] + +Completed by:[**2190-8-24**]",35,2190-08-18 22:14:00,2190-08-24 15:27:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,PNEUMONIA," +# aspiration pneumonia +initially febrile with leukocytosis. patient was intubated in +the ed for concerns regarding airway protection and continued +vomiting. he also received vanc/levo/ flagyl in the ed. vent +settings were gradually weaned and he was easily extubated on +[**2190-8-20**]. he had sputum cultures sent, which grew mrsa and +klebsiella pneumonia. he was on aspiration precautions and +treated with a regimen of vanco and ceftriaxone. however, the +ceftriaxone was switched to meropenem given esbl klebsiella in +the urine. he will complete a 10d course of vanco and a 14d +course of meropenem. at time of discharge, his fevers and +leukocytosis have resolved, he continues to have spo2 in the +upper 90s on room air, and his secretions have improved. + +# hypovolemia +labs initially suggestive of significant volume depletion with +hypotension, increased calcium, bun, hematocrit. he is unable to +independently take pos, and had been vomiting. he received 4l iv +ns in the ed via intraosseous line as no peripherals or central +lines could be placed. also, he was tachycardic, likely both +from volume depletion and holding his antihypertensives due to +hypotension. once in the micu, a r ij tlc was placed. his blood +pressure and heart rate normalized with volume resuscitation, +and his tlc was d/cd once picc access was obtained with ir +assistance. + +# hypertension +occurred a few days after his hypovolemia and hypotension were +corrected. likely due to a rebound effect from being off his +home antihypertensives, especially clonidine. the hypertension +resolved after these medications were resumed, albeit at lower +doses and with clonidine given po. his ekg showed stable lvh and +new twi in the anteroseptal leads. this is nonspecific, but due +to the possibility of ischemia, cardiac markers were checked and +were not elevated when compared to his baseline. he was also +continued on his home aspirin. +- please note that he does not currently have a clonidine patch. +this was written in the discharge medications, but can be placed +at the ecf. +- also, his other antihypertensives are at lower doses - please +titrate to his prior regimen as tolerated. + +# n/v +ct showed no acute abdominal pathology. lfts wnl. neurosurgery +was consulted initially for concern of worsening icp in a +patient with a vp shunt, but felt his head ct was not suggestive +of this. [**name (ni) **] son felt that his mental status was at +baseline. following extubation, tfs were restarted gradually +with high residuals, so he was started on reglan for presumed +diabetic gastroparesis as the cause of his vomiting. there may +have also been contribution by his uti, as this has caused these +symptoms in him previously. + +# uti. urine growing proteus, esbl klebsiella, both sensitive to +meropenem. his inital ceftriaxone and bactrim were switched to +meropenem 500mg q6h and will be continued to complete a 14 day +course. his foley was d/cd and replaced by a condom cath. + +# anemia +hematocrit initially 41.9 due to hemoconcentration from +dehydration. it gradually trended down to a nadir of 23.1. he +received 2 units prbcs, and it remained stable around 32 +subsequently. no coffee grounds were noted since the ed, and his +stool was guaiac negative x2. he was started on lansoprazole. + +# fen +initially had to hold tf for high residuals, but after reglan +was started, we were able to advance him to a goal of 45ml/hr, +which was well tolerated. he received 35 units glargine qhs due +to initial decreased enteral intake, but this was increased to +60 units glargine qhs at discharge as he is at goal with tfs and +having glucose levels upper 200s, lower 300s. +- please uptitrate the glargine to his prior regimen (listed as +78 units qhs) as tolerated. + +# r ue swelling +doppler u/s performed and showed no evidence of dvt. + +# dispo +his other chronic issues remained stable and were treated as +previously. he will be discharged back to the extended care +facility from which he was admitted. + + ","PRIMARY: [Pneumonitis due to inhalation of food or vomitus] +SECONDARY: [Urinary tract infection, site not specified; Pressure ulcer, heel; Pressure ulcer, lower back; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Unspecified essential hypertension; Diabetes with peripheral circulatory disorders, type II or unspecified type, not stated as uncontrolled; Atherosclerosis of native arteries of the extremities, unspecified; Presence of cerebrospinal fluid drainage device; Friedl?nder's bacillus infection in conditions classified elsewhere and of unspecified site; Hypovolemia; Tachycardia, unspecified; Anemia, unspecified; Gastrostomy status; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Gastroparesis; Proteus (mirabilis) (morganii) infection in conditions classified elsewhere and of unspecified site; Abnormal coagulation profile]" +2338,184485.0,9336,2159-09-19,9335,147143.0,2159-08-27,Discharge summary,"Admission Date: [**2159-8-24**] Discharge Date: [**2159-8-27**] + +Date of Birth: [**2097-9-24**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2181**] +Chief Complaint: +Dyspnea + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +61 y.o. Male with h.o. CAD s/p 5v CABG, CHF s/p AICD, systolic +and diastolic dysfunction, hypothyroidism, A. fib p/w dyspnea. + +Pt states that yesterday evening he noted sudden onset of +shortness of breath. He denies any fevers, chills, nausea, +vomiting, chest pain, melena, hemetemesis, hematochezia, +diarrhea, constipation. + +In the [**Name (NI) **] pt's initial VS were noted to be T96.2, HR 68, BP +118/84, RR 24, Sat 96%. His initial EKG was concerning for +possible V tach however on further review it was noted to be A. +fib with aberrancy, pt was given 5mg IV Lopressor which resulted +in decrease of HR from 130s to the low 100s, SBP down to the mid +90s. Pt underwent CXR which showed fluid overload and he was +thus given Furosemide 40mg x 1. He was also given Vancomycin 1gm +IV x 1 due to concern for possible PNA. His labs were notable +for lactate of 13.7, mild leukocytosis of 12.3. ALT/AST were +noted to be 133/243, Alk Phos 257 with a TB of 5.1. His glc was +noted to be 42 with an anion gap acidosis. His INR was noted to +be 3.4, Digoxin level 0.3, BNP 6682. He received a RUQ U/S which +showed edematous gallbladder wall but no cholecystitis, pt also +had cholelithiasis. He also had a right IJ placed and underwent +a CT abdomen/pelvis without contrast to eval for source of high +lactate. CT scna was negative for bowel wall thickening, +pneumotosis but did showed ground glass opacities in the lung. +Prior to the CT scan he was given Levofloxacin and Zosyn given +his acutely ill appearance and elevated lactate. + + +Past Medical History: +CAD s/p CABG +Anterior MI [**2144**] +h/o massive UGIB in [**2154**] [**1-1**] gastritis [**1-1**] NSAIDs and +coumadin(intubated, c/b MRSA VAP, had tracheostomy) +CHF (EF 25% by last echo) with BiV pacer and ICD placement +L hip arthritis +Hyperlipidimia +Hypothyroidism +h/o Afib in past (not currently on coumadin) + +Social History: +Married > 25 years. Has three adult children. Lives with his +wife. Used to work in computers but on disability for health +reasons. Denies tobacco, occasional etoh. No illicits. + + +Family History: +FH: Father died of MI at age 52 + + +Physical Exam: +At Admission: + +General: Chronically sick appearing Male, appears jaundices +lying down in NARD. +HEENT: Left Sclera icteric, EOMI, PERRL +Neck: JVP noted at mandible +Lungs: Crackles noted over right hemithorax and left base. +CV: Distant S1, S2, irregularly irregular, no murmurs, rubs, +gallops +Abdomen: Soft, obese, non-tender, non-distended, bowel sounds +present, no rebound tenderness or guarding, no organomegaly, no +murphys +Ext: Lower extremities cool to touch, sensation intact, movement +intact. Healing wound noted on LLE. + + +Pertinent Results: +[**2159-8-24**] 12:10AM PT-33.9* PTT-35.9* INR(PT)-3.4* +[**2159-8-24**] 12:10AM PLT COUNT-234 +[**2159-8-24**] 12:10AM NEUTS-68.8 LYMPHS-24.3 MONOS-6.2 EOS-0.2 +BASOS-0.5 +[**2159-8-24**] 12:10AM WBC-12.3* RBC-4.98# HGB-12.2* HCT-42.1 +MCV-84# MCH-24.4*# MCHC-28.9*# RDW-18.3* +[**2159-8-24**] 12:10AM DIGOXIN-0.3* +[**2159-8-24**] 12:10AM CALCIUM-8.8 +[**2159-8-24**] 12:10AM CK-MB-6 proBNP-6682* +[**2159-8-24**] 12:10AM cTropnT-0.05* +[**2159-8-24**] 12:10AM LIPASE-25 +[**2159-8-24**] 12:10AM ALT(SGPT)-133* AST(SGOT)-243* CK(CPK)-116 ALK +PHOS-257* TOT BILI-5.1* DIR BILI-2.0* INDIR BIL-3.1 +[**2159-8-24**] 12:10AM GLUCOSE-42* UREA N-22* CREAT-1.5* SODIUM-137 +POTASSIUM-4.7 CHLORIDE-94* TOTAL CO2-17* ANION GAP-31* +[**2159-8-24**] 12:19AM K+-4.2 +[**2159-8-24**] 01:10AM URINE HYALINE-0-2 +[**2159-8-24**] 01:10AM URINE RBC-0-2 WBC-[**2-1**] BACTERIA-MOD YEAST-NONE +EPI-0-2 +[**2159-8-24**] 01:10AM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-15 BILIRUBIN-SM UROBILNGN-12* PH-6.5 LEUK-NEG +[**2159-8-24**] 01:10AM URINE COLOR-Amber APPEAR-Clear SP [**Last Name (un) 155**]-1.018 +[**2159-8-24**] 01:36AM LACTATE-13.7* +[**2159-8-24**] 05:42AM PT-43.7* PTT-42.5* INR(PT)-4.7* +[**2159-8-24**] 05:44AM PLT COUNT-182 +[**2159-8-24**] 05:44AM WBC-11.5* RBC-4.54* HGB-10.8* HCT-38.0* +MCV-84 MCH-23.7* MCHC-28.3* RDW-18.6* +[**2159-8-24**] 05:44AM ALBUMIN-3.5 CALCIUM-8.1* PHOSPHATE-4.4# +MAGNESIUM-2.0 +[**2159-8-24**] 05:44AM CK-MB-NotDone cTropnT-0.05* +[**2159-8-24**] 05:44AM ALT(SGPT)-284* AST(SGOT)-770* LD(LDH)-1290* +CK(CPK)-90 ALK PHOS-219* TOT BILI-5.2* +[**2159-8-24**] 05:44AM GLUCOSE-90 UREA N-24* CREAT-1.4* SODIUM-134 +POTASSIUM-4.2 CHLORIDE-94* TOTAL CO2-17* ANION GAP-27* +[**2159-8-24**] 05:53AM O2 SAT-73 +[**2159-8-24**] 05:53AM LACTATE-11.2* +[**2159-8-24**] 07:18AM TSH-2.8 +[**2159-8-24**] 07:18AM OSMOLAL-291 +[**2159-8-24**] 07:23AM O2 SAT-96 CARBOXYHB-2 +[**2159-8-24**] 07:23AM LACTATE-9.0* +[**2159-8-24**] 07:23AM TYPE-ART PO2-106* PCO2-33* PH-7.39 TOTAL +CO2-21 BASE XS--3 COMMENTS-ADD ON CAR +[**2159-8-24**] 08:33AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-NORMAL POLYCHROM-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2159-8-24**] 09:23AM URINE RBC-[**5-9**]* WBC-[**5-9**]* BACTERIA-MOD +YEAST-NONE EPI-0-2 +[**2159-8-24**] 09:23AM URINE BLOOD-LG NITRITE-NEG PROTEIN-TR +GLUCOSE-NEG KETONE-TR BILIRUBIN-SM UROBILNGN-8* PH-5.0 LEUK-NEG +[**2159-8-24**] 09:23AM URINE COLOR-Amber APPEAR-Clear SP [**Last Name (un) 155**]-1.023 +[**2159-8-24**] 12:49PM ASA-NEG ETHANOL-NEG ACETMNPHN-NEG +bnzodzpn-NEG barbitrt-NEG tricyclic-NEG +[**2159-8-24**] 12:49PM ALT(SGPT)-589* AST(SGOT)-[**2160**]* LD(LDH)-2362* +ALK PHOS-185* TOT BILI-3.8* +[**2159-8-24**] 12:49PM GLUCOSE-99 UREA N-27* CREAT-1.3* SODIUM-135 +POTASSIUM-3.6 CHLORIDE-98 TOTAL CO2-25 ANION GAP-16 +[**2159-8-24**] 12:59PM HGB-10.7* calcHCT-32 O2 SAT-59 +[**2159-8-24**] 12:59PM LACTATE-4.8* +[**2159-8-24**] 12:59PM TYPE-[**Last Name (un) **] PO2-37* PCO2-41 PH-7.37 TOTAL CO2-25 +BASE XS--1 +[**2159-8-24**] 01:33PM O2 SAT-63 +[**2159-8-24**] 07:31PM PLT COUNT-138* +[**2159-8-24**] 07:31PM WBC-10.0 RBC-4.22* HGB-10.4* HCT-34.4* MCV-82 +MCH-24.7* MCHC-30.2* RDW-19.7* +[**2159-8-24**] 07:31PM CALCIUM-8.0* PHOSPHATE-2.6*# MAGNESIUM-1.9 +[**2159-8-24**] 07:31PM ALT(SGPT)-711* AST(SGOT)-2094* LD(LDH)-1775* +ALK PHOS-201* TOT BILI-3.4* +[**2159-8-24**] 07:31PM GLUCOSE-75 UREA N-28* CREAT-1.4* SODIUM-135 +POTASSIUM-3.8 CHLORIDE-96 TOTAL CO2-28 ANION GAP-15 +[**2159-8-24**] 08:36PM LACTATE-3.4* + +Brief Hospital Course: +Patient was admitted on [**2159-8-24**] for acute onset dyspnea. + +Patient is a 61 yom with h.o. of severe systolic and diastolic +function s/p AICD, CAD s/p 5v CABG, hypothyroidism, A. fib p/w +acute onset dyspnea, elevated lactate, transaminitis and fluid +overloaded on exam. + +##. Elevated Lactate: Pt noted to have an elevated lactate of +13.7 on admission. Unclear as to the exact etiology of the +Lactate level. Initial workup included osmolar gap (1), serum +tox (negative), co-oximetry (negative), and cyanide (pending). +Level was followed an rapidly trended down to 3.4 with fluids +and diuresis. Infection was considered however in the setting of +a mild leukocytosis and lack of fever and unconvincing history, +this seemed less likely. Patient was pan cultured and a CXR was +performed demonstrating substantial fluid overload. It was later +felt that the lactate resulted from hypoperfusion stemming from +prolonged SVT with abberancy. Lactate level was 1.7 on the day +of discharge. + +##. Dyspnea/CHF exacerbation: Pt presented to ED with complaint +of SOB of sudden onset with no chest pain. On physical +examination pt noted to have JVP, elevated elevated BNP and CXR +which suggest fluid overload. CHF exacerbation was immediately +suspected, flash pulmonary edema during episode of AF with RVR. +Cardiac enzymes were cylced and were negative and dyspnea +quickly resolved with diuresis. He responded well to IV lasix +(negative > 3 liters on [**2159-8-26**]), and given the concern for +further excess fluid, he was instructed to take 60 mg PO daily +for two days after returning home instead of his usual 40 mg. + +##. Transaminitis/hyperbilirubinemia: Pt noted to have elevated +AST, ALT, TB on admission in the ED. In the ED he received a RUQ +ultrasound which showed cholelithiasis with GB wall edema, per +Radiology was not cholecystitis, as well as moderate ascites. Pt +does have cholelithiasis although no mention is made of any CBD +or prominence. Pt also fluid overloaded on examination, +transaminitis was thought to have resulted from congestive +hepatopathy with possible component of shock liver in setting of +hypoperfusion. Hepatitis serologies were drawn and statin was +held. Liver enzymes trended down over the course of the +admission. Therefore, medications with caution in hepatic +failure were held at discharge (including lorazepam, clonazepam, +simvastatin, midodrine, and zolpidem). + +##. Anion Gap Acidosis: Pt's noted to have metabolic acidosis +with an AG of 26. Likely due to lactic acidosis given his +lactate of 13.7. The gap resolved completely as lactate trended +down. + +##. A. fib with RVR: Pt noted to go into A. fib with RVR in the +ED. Although he received 10 of IV Lopressor, no response noted. +Pt has history of A. fib, not anticoagulated due to a prior GI +bleed whilst on Coumadin. Coumadin was held and sotalol was +continued. EP was consulted and pacer was interrogated +demonstrating no ventricular arrhythmias and multiple episodes +of SVT with aberrancy. They recommended starting amiodarone; +however, patient had allergic reaction to this [**Date Range 4085**] in +past. At discharge, patient was in a paced rhythm at 72 bpm. + +##. Hypothyroidism: patient was continued on synthroid + +##. Systolic/diastolic dysfunction: Pt received an Echo in +[**11/2158**] which was notable for an EF of 20% as well as Grade +III/IV LV diastolic dysfunction. Patient was continued on +digoxin. + +##. Depression: Patient continued on home regimen of Citalopram +and Bupropion. + +##. Insomnia: Patient was taking lorazepam and zolpidem QHS at +home. As these medications should be used with caution in +hepatic impairment, they were held during this admission. The +patient received a single dose of trazodone 25 mg PO. He was +discharged with a prescription for 14 days of trazodone 25 mg to +assist with insomnia until his LFTs can be re-evaluated and a +decision made about a long-term sleeping aid. + +*** FOLLOW UP CARE *** + +Mr. [**Known lastname 31930**] will return home with visiting nurse services to +attend to his wound care as well as to monitor his vitals (low +blood pressure 90s/60s during this admission, but asymptomatic) +and fluid status (assess for volume overload). Mr. [**Known lastname 31930**] will +see a health provider [**Last Name (NamePattern4) **] 1 week, and should have his LFTs, +electrolytes and CBC assessed at that time given the +abnormalities noted prior to discharge to confirm that these +values continue to stabilize. If LFTs have returned to [**Location 213**], +consider restarting prior home medications which were held in +the setting of transaminitis (statin, zolpidem, clonazepam, +lorazepam, midodrine). He should also have BP checked +(orthostatics performed, given his history) and volume status +assessed - he may require increase in baseline lasix. + +Medications on Admission: +Bupropion 100 mg po bid +Citalopram 10 mg daily +Clonazepam 0.5 mg po bid +Digoxin 125 mcg, 1 tab/2 tabs alterating +Lasix 40 mg daily +Levothyroxine 50 mcg daily +Lorazepam 4 mg qhs +Midodrine 1 mg po tid +Simvastatin 40 mg daily +Sotalol 120 mg po bid +Spironolactone 12.5 mg daily +Triamcinolone 0.1% ointment +Zolpidem 10 mg qhs + + +Discharge Medications: +1. Bupropion HCl 100 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +2. Digoxin 125 mcg Tablet Sig: 1-2 Tablets PO Alternate 1 or 2 +tabs every other day. +3. Citalopram 20 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +4. Levothyroxine 50 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +Take 1.5 tablets on [**2159-8-28**] (tomorrow) and [**2159-8-29**] (Wednesday), +then resume 1 tablet per day. +6. Sotalol 80 mg Tablet Sig: 1.5 Tablets PO BID (2 times a day). + +7. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +8. Trazodone 50 mg Tablet Sig: 0.5 Tablet PO at bedtime as +needed for insomnia for 7 days. +Disp:*7 Tablet(s)* Refills:*0* +9. Triamcinolone Acetonide 0.1 % Ointment Topical + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] Home Health Care + +Discharge Diagnosis: +Primary Diagnosis: +CHF exacerbation +Congestive hepatopathy +Paroxysmal atrial fibrillation with rapid ventricular rate + +Secondary Diagnosis: +Hypothyroidism +Orthostatic hypotension + + +Discharge Condition: +good, respiratory status back to baseline + + +Discharge Instructions: +You were admitted to the hospital because you developed acute +shortness of breath and weakness. Upon admission we discovered +that your heart was in an abnormal rhythm called atrial +fibrillation with rapid ventricular response. This means that +your heart was not able to pump blood appropriately because of +this and because of your congestive heart failure. This allowed +fluid to fill your lungs and made you feel short of breath. You +were initially admitted to the ICU were it was discovered that +this had not only affected your heart and lungs but also your +liver. You were treated with a [**Hospital 4085**] called lasix which +helped you cleared this fluid from your lungs. Your condition +improved with just one dose of this [**Hospital 4085**]. You were +subsequently transfered to the medical floor. We continued your +lasix and your condition improved even more. As a result of this +treatment your liver also recovered and it is now recovering. + +We made the following changes to your medications: +1. STOP TAKING simvastatin until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +2. STOP TAKING clonazepam until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +3. STOP TAKING lorazepam until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +4. STOP TAKING zolpidem until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +5. STOP TAKING midodrine until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +6. INCREASE DOSE of Lasix (furosemide) to 60 mg (1.5 tablets) by +mouth daily for 2 days (tomorrow and Wednesday). Then resume +your usual dose of 40 mg by mouth daily starting on Thursday. + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +Adhere to 2 gm sodium diet +Fluid Restriction: 1500 mL of fluid per day + +If you at any point experience chest pain, shortness of breath, +weakness, nausea, vomiting, abnormal heart beats, increased leg +swelling, defibrillator firing, fevers, chills or any other +symptom that concerns you please return to the hospital or +contact your PCP or your [**Name9 (PRE) 31931**] for further evaluation. + +Please keep the follow-up appointments as outlined below. + +Followup Instructions: +Please keep the following appointments: + +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone: [**Telephone/Fax (1) 250**] +Date/Time: [**2159-9-5**] at 2:10 pm + +Provider: [**Doctor Last Name 31929**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time: [**2159-9-21**] at 2:50 pm + +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] +Date/Time: [**2159-9-27**] 9:30 am + +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 62**] +Date/Time: [**2159-9-27**] 10:20 am + + + +Completed by:[**2159-8-27**]",23,2159-08-24 01:18:00,2159-08-27 17:33:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CONGESTIVE HEART FAILURE," +patient was admitted on [**2159-8-24**] for acute onset dyspnea. + +patient is a 61 yom with h.o. of severe systolic and diastolic +function s/p aicd, cad s/p 5v cabg, hypothyroidism, a. fib p/w +acute onset dyspnea, elevated lactate, transaminitis and fluid +overloaded on exam. + +##. elevated lactate: pt noted to have an elevated lactate of +13.7 on admission. unclear as to the exact etiology of the +lactate level. initial workup included osmolar gap (1), serum +tox (negative), co-oximetry (negative), and cyanide (pending). +level was followed an rapidly trended down to 3.4 with fluids +and diuresis. infection was considered however in the setting of +a mild leukocytosis and lack of fever and unconvincing history, +this seemed less likely. patient was pan cultured and a cxr was +performed demonstrating substantial fluid overload. it was later +felt that the lactate resulted from hypoperfusion stemming from +prolonged svt with abberancy. lactate level was 1.7 on the day +of discharge. + +##. dyspnea/chf exacerbation: pt presented to ed with complaint +of sob of sudden onset with no chest pain. on physical +examination pt noted to have jvp, elevated elevated bnp and cxr +which suggest fluid overload. chf exacerbation was immediately +suspected, flash pulmonary edema during episode of af with rvr. +cardiac enzymes were cylced and were negative and dyspnea +quickly resolved with diuresis. he responded well to iv lasix +(negative > 3 liters on [**2159-8-26**]), and given the concern for +further excess fluid, he was instructed to take 60 mg po daily +for two days after returning home instead of his usual 40 mg. + +##. transaminitis/hyperbilirubinemia: pt noted to have elevated +ast, alt, tb on admission in the ed. in the ed he received a ruq +ultrasound which showed cholelithiasis with gb wall edema, per +radiology was not cholecystitis, as well as moderate ascites. pt +does have cholelithiasis although no mention is made of any cbd +or prominence. pt also fluid overloaded on examination, +transaminitis was thought to have resulted from congestive +hepatopathy with possible component of shock liver in setting of +hypoperfusion. hepatitis serologies were drawn and statin was +held. liver enzymes trended down over the course of the +admission. therefore, medications with caution in hepatic +failure were held at discharge (including lorazepam, clonazepam, +simvastatin, midodrine, and zolpidem). + +##. anion gap acidosis: pts noted to have metabolic acidosis +with an ag of 26. likely due to lactic acidosis given his +lactate of 13.7. the gap resolved completely as lactate trended +down. + +##. a. fib with rvr: pt noted to go into a. fib with rvr in the +ed. although he received 10 of iv lopressor, no response noted. +pt has history of a. fib, not anticoagulated due to a prior gi +bleed whilst on coumadin. coumadin was held and sotalol was +continued. ep was consulted and pacer was interrogated +demonstrating no ventricular arrhythmias and multiple episodes +of svt with aberrancy. they recommended starting amiodarone; +however, patient had allergic reaction to this [**date range 4085**] in +past. at discharge, patient was in a paced rhythm at 72 bpm. + +##. hypothyroidism: patient was continued on synthroid + +##. systolic/diastolic dysfunction: pt received an echo in +[**11/2158**] which was notable for an ef of 20% as well as grade +iii/iv lv diastolic dysfunction. patient was continued on +digoxin. + +##. depression: patient continued on home regimen of citalopram +and bupropion. + +##. insomnia: patient was taking lorazepam and zolpidem qhs at +home. as these medications should be used with caution in +hepatic impairment, they were held during this admission. the +patient received a single dose of trazodone 25 mg po. he was +discharged with a prescription for 14 days of trazodone 25 mg to +assist with insomnia until his lfts can be re-evaluated and a +decision made about a long-term sleeping aid. + +*** follow up care *** + +mr. [**known lastname 31930**] will return home with visiting nurse services to +attend to his wound care as well as to monitor his vitals (low +blood pressure 90s/60s during this admission, but asymptomatic) +and fluid status (assess for volume overload). mr. [**known lastname 31930**] will +see a health provider [**last name (namepattern4) **] 1 week, and should have his lfts, +electrolytes and cbc assessed at that time given the +abnormalities noted prior to discharge to confirm that these +values continue to stabilize. if lfts have returned to [**location 213**], +consider restarting prior home medications which were held in +the setting of transaminitis (statin, zolpidem, clonazepam, +lorazepam, midodrine). he should also have bp checked +(orthostatics performed, given his history) and volume status +assessed - he may require increase in baseline lasix. + + ","PRIMARY: [Acute on chronic combined systolic and diastolic heart failure] +SECONDARY: [Acidosis; Other primary cardiomyopathies; Congestive heart failure, unspecified; Hepatitis, unspecified; Atrial fibrillation; Atherosclerosis of native arteries of the extremities with ulceration; Orthostatic hypotension; Ulcer of other part of foot; Unspecified acquired hypothyroidism; Impotence of organic origin; Other and unspecified hyperlipidemia; Aortocoronary bypass status; Dysthymic disorder; Automatic implantable cardiac defibrillator in situ]" +2338,114726.0,9337,2159-10-29,9335,147143.0,2159-08-27,Discharge summary,"Admission Date: [**2159-8-24**] Discharge Date: [**2159-8-27**] + +Date of Birth: [**2097-9-24**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2181**] +Chief Complaint: +Dyspnea + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +61 y.o. Male with h.o. CAD s/p 5v CABG, CHF s/p AICD, systolic +and diastolic dysfunction, hypothyroidism, A. fib p/w dyspnea. + +Pt states that yesterday evening he noted sudden onset of +shortness of breath. He denies any fevers, chills, nausea, +vomiting, chest pain, melena, hemetemesis, hematochezia, +diarrhea, constipation. + +In the [**Name (NI) **] pt's initial VS were noted to be T96.2, HR 68, BP +118/84, RR 24, Sat 96%. His initial EKG was concerning for +possible V tach however on further review it was noted to be A. +fib with aberrancy, pt was given 5mg IV Lopressor which resulted +in decrease of HR from 130s to the low 100s, SBP down to the mid +90s. Pt underwent CXR which showed fluid overload and he was +thus given Furosemide 40mg x 1. He was also given Vancomycin 1gm +IV x 1 due to concern for possible PNA. His labs were notable +for lactate of 13.7, mild leukocytosis of 12.3. ALT/AST were +noted to be 133/243, Alk Phos 257 with a TB of 5.1. His glc was +noted to be 42 with an anion gap acidosis. His INR was noted to +be 3.4, Digoxin level 0.3, BNP 6682. He received a RUQ U/S which +showed edematous gallbladder wall but no cholecystitis, pt also +had cholelithiasis. He also had a right IJ placed and underwent +a CT abdomen/pelvis without contrast to eval for source of high +lactate. CT scna was negative for bowel wall thickening, +pneumotosis but did showed ground glass opacities in the lung. +Prior to the CT scan he was given Levofloxacin and Zosyn given +his acutely ill appearance and elevated lactate. + + +Past Medical History: +CAD s/p CABG +Anterior MI [**2144**] +h/o massive UGIB in [**2154**] [**1-1**] gastritis [**1-1**] NSAIDs and +coumadin(intubated, c/b MRSA VAP, had tracheostomy) +CHF (EF 25% by last echo) with BiV pacer and ICD placement +L hip arthritis +Hyperlipidimia +Hypothyroidism +h/o Afib in past (not currently on coumadin) + +Social History: +Married > 25 years. Has three adult children. Lives with his +wife. Used to work in computers but on disability for health +reasons. Denies tobacco, occasional etoh. No illicits. + + +Family History: +FH: Father died of MI at age 52 + + +Physical Exam: +At Admission: + +General: Chronically sick appearing Male, appears jaundices +lying down in NARD. +HEENT: Left Sclera icteric, EOMI, PERRL +Neck: JVP noted at mandible +Lungs: Crackles noted over right hemithorax and left base. +CV: Distant S1, S2, irregularly irregular, no murmurs, rubs, +gallops +Abdomen: Soft, obese, non-tender, non-distended, bowel sounds +present, no rebound tenderness or guarding, no organomegaly, no +murphys +Ext: Lower extremities cool to touch, sensation intact, movement +intact. Healing wound noted on LLE. + + +Pertinent Results: +[**2159-8-24**] 12:10AM PT-33.9* PTT-35.9* INR(PT)-3.4* +[**2159-8-24**] 12:10AM PLT COUNT-234 +[**2159-8-24**] 12:10AM NEUTS-68.8 LYMPHS-24.3 MONOS-6.2 EOS-0.2 +BASOS-0.5 +[**2159-8-24**] 12:10AM WBC-12.3* RBC-4.98# HGB-12.2* HCT-42.1 +MCV-84# MCH-24.4*# MCHC-28.9*# RDW-18.3* +[**2159-8-24**] 12:10AM DIGOXIN-0.3* +[**2159-8-24**] 12:10AM CALCIUM-8.8 +[**2159-8-24**] 12:10AM CK-MB-6 proBNP-6682* +[**2159-8-24**] 12:10AM cTropnT-0.05* +[**2159-8-24**] 12:10AM LIPASE-25 +[**2159-8-24**] 12:10AM ALT(SGPT)-133* AST(SGOT)-243* CK(CPK)-116 ALK +PHOS-257* TOT BILI-5.1* DIR BILI-2.0* INDIR BIL-3.1 +[**2159-8-24**] 12:10AM GLUCOSE-42* UREA N-22* CREAT-1.5* SODIUM-137 +POTASSIUM-4.7 CHLORIDE-94* TOTAL CO2-17* ANION GAP-31* +[**2159-8-24**] 12:19AM K+-4.2 +[**2159-8-24**] 01:10AM URINE HYALINE-0-2 +[**2159-8-24**] 01:10AM URINE RBC-0-2 WBC-[**2-1**] BACTERIA-MOD YEAST-NONE +EPI-0-2 +[**2159-8-24**] 01:10AM URINE BLOOD-NEG NITRITE-NEG PROTEIN-100 +GLUCOSE-NEG KETONE-15 BILIRUBIN-SM UROBILNGN-12* PH-6.5 LEUK-NEG +[**2159-8-24**] 01:10AM URINE COLOR-Amber APPEAR-Clear SP [**Last Name (un) 155**]-1.018 +[**2159-8-24**] 01:36AM LACTATE-13.7* +[**2159-8-24**] 05:42AM PT-43.7* PTT-42.5* INR(PT)-4.7* +[**2159-8-24**] 05:44AM PLT COUNT-182 +[**2159-8-24**] 05:44AM WBC-11.5* RBC-4.54* HGB-10.8* HCT-38.0* +MCV-84 MCH-23.7* MCHC-28.3* RDW-18.6* +[**2159-8-24**] 05:44AM ALBUMIN-3.5 CALCIUM-8.1* PHOSPHATE-4.4# +MAGNESIUM-2.0 +[**2159-8-24**] 05:44AM CK-MB-NotDone cTropnT-0.05* +[**2159-8-24**] 05:44AM ALT(SGPT)-284* AST(SGOT)-770* LD(LDH)-1290* +CK(CPK)-90 ALK PHOS-219* TOT BILI-5.2* +[**2159-8-24**] 05:44AM GLUCOSE-90 UREA N-24* CREAT-1.4* SODIUM-134 +POTASSIUM-4.2 CHLORIDE-94* TOTAL CO2-17* ANION GAP-27* +[**2159-8-24**] 05:53AM O2 SAT-73 +[**2159-8-24**] 05:53AM LACTATE-11.2* +[**2159-8-24**] 07:18AM TSH-2.8 +[**2159-8-24**] 07:18AM OSMOLAL-291 +[**2159-8-24**] 07:23AM O2 SAT-96 CARBOXYHB-2 +[**2159-8-24**] 07:23AM LACTATE-9.0* +[**2159-8-24**] 07:23AM TYPE-ART PO2-106* PCO2-33* PH-7.39 TOTAL +CO2-21 BASE XS--3 COMMENTS-ADD ON CAR +[**2159-8-24**] 08:33AM HYPOCHROM-2+ ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-1+ MICROCYT-NORMAL POLYCHROM-OCCASIONAL +SCHISTOCY-OCCASIONAL BURR-OCCASIONAL ELLIPTOCY-OCCASIONAL +[**2159-8-24**] 09:23AM URINE RBC-[**5-9**]* WBC-[**5-9**]* BACTERIA-MOD +YEAST-NONE EPI-0-2 +[**2159-8-24**] 09:23AM URINE BLOOD-LG NITRITE-NEG PROTEIN-TR +GLUCOSE-NEG KETONE-TR BILIRUBIN-SM UROBILNGN-8* PH-5.0 LEUK-NEG +[**2159-8-24**] 09:23AM URINE COLOR-Amber APPEAR-Clear SP [**Last Name (un) 155**]-1.023 +[**2159-8-24**] 12:49PM ASA-NEG ETHANOL-NEG ACETMNPHN-NEG +bnzodzpn-NEG barbitrt-NEG tricyclic-NEG +[**2159-8-24**] 12:49PM ALT(SGPT)-589* AST(SGOT)-[**2160**]* LD(LDH)-2362* +ALK PHOS-185* TOT BILI-3.8* +[**2159-8-24**] 12:49PM GLUCOSE-99 UREA N-27* CREAT-1.3* SODIUM-135 +POTASSIUM-3.6 CHLORIDE-98 TOTAL CO2-25 ANION GAP-16 +[**2159-8-24**] 12:59PM HGB-10.7* calcHCT-32 O2 SAT-59 +[**2159-8-24**] 12:59PM LACTATE-4.8* +[**2159-8-24**] 12:59PM TYPE-[**Last Name (un) **] PO2-37* PCO2-41 PH-7.37 TOTAL CO2-25 +BASE XS--1 +[**2159-8-24**] 01:33PM O2 SAT-63 +[**2159-8-24**] 07:31PM PLT COUNT-138* +[**2159-8-24**] 07:31PM WBC-10.0 RBC-4.22* HGB-10.4* HCT-34.4* MCV-82 +MCH-24.7* MCHC-30.2* RDW-19.7* +[**2159-8-24**] 07:31PM CALCIUM-8.0* PHOSPHATE-2.6*# MAGNESIUM-1.9 +[**2159-8-24**] 07:31PM ALT(SGPT)-711* AST(SGOT)-2094* LD(LDH)-1775* +ALK PHOS-201* TOT BILI-3.4* +[**2159-8-24**] 07:31PM GLUCOSE-75 UREA N-28* CREAT-1.4* SODIUM-135 +POTASSIUM-3.8 CHLORIDE-96 TOTAL CO2-28 ANION GAP-15 +[**2159-8-24**] 08:36PM LACTATE-3.4* + +Brief Hospital Course: +Patient was admitted on [**2159-8-24**] for acute onset dyspnea. + +Patient is a 61 yom with h.o. of severe systolic and diastolic +function s/p AICD, CAD s/p 5v CABG, hypothyroidism, A. fib p/w +acute onset dyspnea, elevated lactate, transaminitis and fluid +overloaded on exam. + +##. Elevated Lactate: Pt noted to have an elevated lactate of +13.7 on admission. Unclear as to the exact etiology of the +Lactate level. Initial workup included osmolar gap (1), serum +tox (negative), co-oximetry (negative), and cyanide (pending). +Level was followed an rapidly trended down to 3.4 with fluids +and diuresis. Infection was considered however in the setting of +a mild leukocytosis and lack of fever and unconvincing history, +this seemed less likely. Patient was pan cultured and a CXR was +performed demonstrating substantial fluid overload. It was later +felt that the lactate resulted from hypoperfusion stemming from +prolonged SVT with abberancy. Lactate level was 1.7 on the day +of discharge. + +##. Dyspnea/CHF exacerbation: Pt presented to ED with complaint +of SOB of sudden onset with no chest pain. On physical +examination pt noted to have JVP, elevated elevated BNP and CXR +which suggest fluid overload. CHF exacerbation was immediately +suspected, flash pulmonary edema during episode of AF with RVR. +Cardiac enzymes were cylced and were negative and dyspnea +quickly resolved with diuresis. He responded well to IV lasix +(negative > 3 liters on [**2159-8-26**]), and given the concern for +further excess fluid, he was instructed to take 60 mg PO daily +for two days after returning home instead of his usual 40 mg. + +##. Transaminitis/hyperbilirubinemia: Pt noted to have elevated +AST, ALT, TB on admission in the ED. In the ED he received a RUQ +ultrasound which showed cholelithiasis with GB wall edema, per +Radiology was not cholecystitis, as well as moderate ascites. Pt +does have cholelithiasis although no mention is made of any CBD +or prominence. Pt also fluid overloaded on examination, +transaminitis was thought to have resulted from congestive +hepatopathy with possible component of shock liver in setting of +hypoperfusion. Hepatitis serologies were drawn and statin was +held. Liver enzymes trended down over the course of the +admission. Therefore, medications with caution in hepatic +failure were held at discharge (including lorazepam, clonazepam, +simvastatin, midodrine, and zolpidem). + +##. Anion Gap Acidosis: Pt's noted to have metabolic acidosis +with an AG of 26. Likely due to lactic acidosis given his +lactate of 13.7. The gap resolved completely as lactate trended +down. + +##. A. fib with RVR: Pt noted to go into A. fib with RVR in the +ED. Although he received 10 of IV Lopressor, no response noted. +Pt has history of A. fib, not anticoagulated due to a prior GI +bleed whilst on Coumadin. Coumadin was held and sotalol was +continued. EP was consulted and pacer was interrogated +demonstrating no ventricular arrhythmias and multiple episodes +of SVT with aberrancy. They recommended starting amiodarone; +however, patient had allergic reaction to this [**Date Range 4085**] in +past. At discharge, patient was in a paced rhythm at 72 bpm. + +##. Hypothyroidism: patient was continued on synthroid + +##. Systolic/diastolic dysfunction: Pt received an Echo in +[**11/2158**] which was notable for an EF of 20% as well as Grade +III/IV LV diastolic dysfunction. Patient was continued on +digoxin. + +##. Depression: Patient continued on home regimen of Citalopram +and Bupropion. + +##. Insomnia: Patient was taking lorazepam and zolpidem QHS at +home. As these medications should be used with caution in +hepatic impairment, they were held during this admission. The +patient received a single dose of trazodone 25 mg PO. He was +discharged with a prescription for 14 days of trazodone 25 mg to +assist with insomnia until his LFTs can be re-evaluated and a +decision made about a long-term sleeping aid. + +*** FOLLOW UP CARE *** + +Mr. [**Known lastname 31930**] will return home with visiting nurse services to +attend to his wound care as well as to monitor his vitals (low +blood pressure 90s/60s during this admission, but asymptomatic) +and fluid status (assess for volume overload). Mr. [**Known lastname 31930**] will +see a health provider [**Last Name (NamePattern4) **] 1 week, and should have his LFTs, +electrolytes and CBC assessed at that time given the +abnormalities noted prior to discharge to confirm that these +values continue to stabilize. If LFTs have returned to [**Location 213**], +consider restarting prior home medications which were held in +the setting of transaminitis (statin, zolpidem, clonazepam, +lorazepam, midodrine). He should also have BP checked +(orthostatics performed, given his history) and volume status +assessed - he may require increase in baseline lasix. + +Medications on Admission: +Bupropion 100 mg po bid +Citalopram 10 mg daily +Clonazepam 0.5 mg po bid +Digoxin 125 mcg, 1 tab/2 tabs alterating +Lasix 40 mg daily +Levothyroxine 50 mcg daily +Lorazepam 4 mg qhs +Midodrine 1 mg po tid +Simvastatin 40 mg daily +Sotalol 120 mg po bid +Spironolactone 12.5 mg daily +Triamcinolone 0.1% ointment +Zolpidem 10 mg qhs + + +Discharge Medications: +1. Bupropion HCl 100 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +2. Digoxin 125 mcg Tablet Sig: 1-2 Tablets PO Alternate 1 or 2 +tabs every other day. +3. Citalopram 20 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +4. Levothyroxine 50 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +Take 1.5 tablets on [**2159-8-28**] (tomorrow) and [**2159-8-29**] (Wednesday), +then resume 1 tablet per day. +6. Sotalol 80 mg Tablet Sig: 1.5 Tablets PO BID (2 times a day). + +7. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +8. Trazodone 50 mg Tablet Sig: 0.5 Tablet PO at bedtime as +needed for insomnia for 7 days. +Disp:*7 Tablet(s)* Refills:*0* +9. Triamcinolone Acetonide 0.1 % Ointment Topical + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] Home Health Care + +Discharge Diagnosis: +Primary Diagnosis: +CHF exacerbation +Congestive hepatopathy +Paroxysmal atrial fibrillation with rapid ventricular rate + +Secondary Diagnosis: +Hypothyroidism +Orthostatic hypotension + + +Discharge Condition: +good, respiratory status back to baseline + + +Discharge Instructions: +You were admitted to the hospital because you developed acute +shortness of breath and weakness. Upon admission we discovered +that your heart was in an abnormal rhythm called atrial +fibrillation with rapid ventricular response. This means that +your heart was not able to pump blood appropriately because of +this and because of your congestive heart failure. This allowed +fluid to fill your lungs and made you feel short of breath. You +were initially admitted to the ICU were it was discovered that +this had not only affected your heart and lungs but also your +liver. You were treated with a [**Hospital 4085**] called lasix which +helped you cleared this fluid from your lungs. Your condition +improved with just one dose of this [**Hospital 4085**]. You were +subsequently transfered to the medical floor. We continued your +lasix and your condition improved even more. As a result of this +treatment your liver also recovered and it is now recovering. + +We made the following changes to your medications: +1. STOP TAKING simvastatin until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +2. STOP TAKING clonazepam until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +3. STOP TAKING lorazepam until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +4. STOP TAKING zolpidem until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +5. STOP TAKING midodrine until directed to resume use by your +doctor. [**First Name (Titles) **] [**Last Name (Titles) 4085**] may cause liver damage if taken at this +time. +6. INCREASE DOSE of Lasix (furosemide) to 60 mg (1.5 tablets) by +mouth daily for 2 days (tomorrow and Wednesday). Then resume +your usual dose of 40 mg by mouth daily starting on Thursday. + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +Adhere to 2 gm sodium diet +Fluid Restriction: 1500 mL of fluid per day + +If you at any point experience chest pain, shortness of breath, +weakness, nausea, vomiting, abnormal heart beats, increased leg +swelling, defibrillator firing, fevers, chills or any other +symptom that concerns you please return to the hospital or +contact your PCP or your [**Name9 (PRE) 31931**] for further evaluation. + +Please keep the follow-up appointments as outlined below. + +Followup Instructions: +Please keep the following appointments: + +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone: [**Telephone/Fax (1) 250**] +Date/Time: [**2159-9-5**] at 2:10 pm + +Provider: [**Doctor Last Name 31929**], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time: [**2159-9-21**] at 2:50 pm + +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] +Date/Time: [**2159-9-27**] 9:30 am + +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 62**] +Date/Time: [**2159-9-27**] 10:20 am + + + +Completed by:[**2159-8-27**]",63,2159-08-24 01:18:00,2159-08-27 17:33:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CONGESTIVE HEART FAILURE," +patient was admitted on [**2159-8-24**] for acute onset dyspnea. + +patient is a 61 yom with h.o. of severe systolic and diastolic +function s/p aicd, cad s/p 5v cabg, hypothyroidism, a. fib p/w +acute onset dyspnea, elevated lactate, transaminitis and fluid +overloaded on exam. + +##. elevated lactate: pt noted to have an elevated lactate of +13.7 on admission. unclear as to the exact etiology of the +lactate level. initial workup included osmolar gap (1), serum +tox (negative), co-oximetry (negative), and cyanide (pending). +level was followed an rapidly trended down to 3.4 with fluids +and diuresis. infection was considered however in the setting of +a mild leukocytosis and lack of fever and unconvincing history, +this seemed less likely. patient was pan cultured and a cxr was +performed demonstrating substantial fluid overload. it was later +felt that the lactate resulted from hypoperfusion stemming from +prolonged svt with abberancy. lactate level was 1.7 on the day +of discharge. + +##. dyspnea/chf exacerbation: pt presented to ed with complaint +of sob of sudden onset with no chest pain. on physical +examination pt noted to have jvp, elevated elevated bnp and cxr +which suggest fluid overload. chf exacerbation was immediately +suspected, flash pulmonary edema during episode of af with rvr. +cardiac enzymes were cylced and were negative and dyspnea +quickly resolved with diuresis. he responded well to iv lasix +(negative > 3 liters on [**2159-8-26**]), and given the concern for +further excess fluid, he was instructed to take 60 mg po daily +for two days after returning home instead of his usual 40 mg. + +##. transaminitis/hyperbilirubinemia: pt noted to have elevated +ast, alt, tb on admission in the ed. in the ed he received a ruq +ultrasound which showed cholelithiasis with gb wall edema, per +radiology was not cholecystitis, as well as moderate ascites. pt +does have cholelithiasis although no mention is made of any cbd +or prominence. pt also fluid overloaded on examination, +transaminitis was thought to have resulted from congestive +hepatopathy with possible component of shock liver in setting of +hypoperfusion. hepatitis serologies were drawn and statin was +held. liver enzymes trended down over the course of the +admission. therefore, medications with caution in hepatic +failure were held at discharge (including lorazepam, clonazepam, +simvastatin, midodrine, and zolpidem). + +##. anion gap acidosis: pts noted to have metabolic acidosis +with an ag of 26. likely due to lactic acidosis given his +lactate of 13.7. the gap resolved completely as lactate trended +down. + +##. a. fib with rvr: pt noted to go into a. fib with rvr in the +ed. although he received 10 of iv lopressor, no response noted. +pt has history of a. fib, not anticoagulated due to a prior gi +bleed whilst on coumadin. coumadin was held and sotalol was +continued. ep was consulted and pacer was interrogated +demonstrating no ventricular arrhythmias and multiple episodes +of svt with aberrancy. they recommended starting amiodarone; +however, patient had allergic reaction to this [**date range 4085**] in +past. at discharge, patient was in a paced rhythm at 72 bpm. + +##. hypothyroidism: patient was continued on synthroid + +##. systolic/diastolic dysfunction: pt received an echo in +[**11/2158**] which was notable for an ef of 20% as well as grade +iii/iv lv diastolic dysfunction. patient was continued on +digoxin. + +##. depression: patient continued on home regimen of citalopram +and bupropion. + +##. insomnia: patient was taking lorazepam and zolpidem qhs at +home. as these medications should be used with caution in +hepatic impairment, they were held during this admission. the +patient received a single dose of trazodone 25 mg po. he was +discharged with a prescription for 14 days of trazodone 25 mg to +assist with insomnia until his lfts can be re-evaluated and a +decision made about a long-term sleeping aid. + +*** follow up care *** + +mr. [**known lastname 31930**] will return home with visiting nurse services to +attend to his wound care as well as to monitor his vitals (low +blood pressure 90s/60s during this admission, but asymptomatic) +and fluid status (assess for volume overload). mr. [**known lastname 31930**] will +see a health provider [**last name (namepattern4) **] 1 week, and should have his lfts, +electrolytes and cbc assessed at that time given the +abnormalities noted prior to discharge to confirm that these +values continue to stabilize. if lfts have returned to [**location 213**], +consider restarting prior home medications which were held in +the setting of transaminitis (statin, zolpidem, clonazepam, +lorazepam, midodrine). he should also have bp checked +(orthostatics performed, given his history) and volume status +assessed - he may require increase in baseline lasix. + + ","PRIMARY: [Acute on chronic combined systolic and diastolic heart failure] +SECONDARY: [Acidosis; Other primary cardiomyopathies; Congestive heart failure, unspecified; Hepatitis, unspecified; Atrial fibrillation; Atherosclerosis of native arteries of the extremities with ulceration; Orthostatic hypotension; Ulcer of other part of foot; Unspecified acquired hypothyroidism; Impotence of organic origin; Other and unspecified hyperlipidemia; Aortocoronary bypass status; Dysthymic disorder; Automatic implantable cardiac defibrillator in situ]" +2338,114726.0,9337,2159-10-29,9336,184485.0,2159-09-19,Discharge summary,"Admission Date: [**2159-9-14**] Discharge Date: [**2159-9-19**] + +Date of Birth: [**2097-9-24**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Amiodarone + +Attending:[**First Name3 (LF) 458**] +Chief Complaint: +ICD firing + +Major Surgical or Invasive Procedure: +external DC/CV +intubation + + +History of Present Illness: +Mr. [**Known lastname 31930**] is a 61 year old male with a history of coronary +artery disease s/p MI and CABG, chronic systolic heart failure, +recurrent VT s/p ICD placement and atrial fibrillation who +presents from home with recurrent ICD firing. Patient reports +being in his usual state of health until 3 PM on the day prior +to admission. He stopped taking his sotalol approximately 2 +weeks prior to admission for unclear reasons. He did not +discuss this with his cardiologist Dr. [**Last Name (STitle) **]. Over the past +few weeks since discontinuing this [**Last Name (STitle) 4085**] he has noted +decreased exercise tolerance and worsening dyspnea on exertion. +He typically can walk half a block but now can only walk around +his home. He has not been experiencing any fevers or chills. +He has not had any episodes of chest pain. He denies worsening +orthopnea or PND but does endorse worsening nocturia. He denies +worsening lower extremity edema. At 3 PM on the day prior to +admission his ICD fired. He has had firings before and he +denies any precipitating events. His ICD has since fired 8 +times in 12 hours. He has never had repeated firings before. +He decided to come to the emergency room. +. +In the ED, initial vitals were T: 97.8 BP: 150/98 HR: 73 RR: 18 +O2: 99% on RA. EKG shows atrial fibrillation with rapid +response in the 140s with intermittent demand pacing, +intraventricular conduction delay left bundle branch block +pattern, no gross ischemic changes, no change from prior dated +[**2159-8-24**]. Two episodes of vtach in the ED without firing. EP +recommended rate control of his RVR and some lasix. He received +diltiazem 10 mg IV x 1 and lasix 80 mg IV x 1. +. +On review of systems he denies fevers, chills, cough, +congestion, nausea, vomiting, abdominal pain, diarrhea, +constipation, dysuria, hematuria, leg pain. He denies chest +pain, orthopnea, PND. He endorses worsening dyspnea on exertion +and nocturia. He has significant lower extremity edema on exam +but denies worsening. + +Past Medical History: +Coronary Artery Disease s/p 5 vessel CABG in [**2144**] +Anterior MI [**2144**] +Large UGIB in [**2154**] thought to be secondary to a combination of +gastritis, nsaids, and coumadin (required intubation and +tracheostomy secondary to MRSA ventilator associated pneumonia) + +Chronic systolic heart failure (EF 20% by last echocardiogram) +History of VT s/p BiV pacer and ICD placement in [**2144**] now s/p +multiple device changes most recently in [**2157**]. +Left hip arthritis +Hyperlipidimia +Hypothyroidism +Atrial Fibrillation (not on anticoagulation secondary to GI +bleeding) +Osteomyelolitis on L foot +1. CARDIAC RISK FACTORS: Dyslipidemia +2. CARDIAC HISTORY: +-CABG: Five vessel CABG in [**2144**] +-PERCUTANEOUS CORONARY INTERVENTIONS: +-PACING/ICD: [**Company 1543**] Concerto biventricular ICD placed in +[**2158-3-30**]. He has three leads. The RV lead is a [**Company 1543**] 6943 +implanted [**2150-9-18**]. The atrial lead is a Guidant 4464 +also implanted in [**2150-8-30**]. His LV lead is a [**Company 1543**] 4193 +implanted in [**2153-7-30**] and the ICD device was implanted in +[**2158-3-30**]. + + +Physical Exam: +PHYSICAL EXAMINATION: +VS: T: 96.7 HR: 100 BP: 93/72 RR: 18 O2: 97% on RA +GENERAL: AOriented x3. Mood, affect appropriate. +HEENT: Sclera anicteric. PERRL, EOMI. Conjunctiva were pink, no +pallor or cyanosis of the oral mucosa. No xanthalesma. +NECK: +JVD +CARDIAC: irregularly irregular rhythm, tachy. No m/r/g. +LUNGS: Resp were unlabored, no accessory muscle use. bilateral +crackles half way up lung fields. ICD pocket w/o erythema, +warmth or any sign of infection +ABDOMEN: Soft, NTND. No HSM or tenderness. Abd aorta not +enlarged by palpation. No abdominial bruits. +EXTREMITIES: No c/c/e. No femoral bruits. erythema on L anterior +leg, no drainage or tenderness. healing ulcer on L foot. + + +Pertinent Results: +EKG: Afib RVR in the 140s with intermittent demand pacing, left +bundle branch block, no gross ischemic changes, no change from +prior dated [**2159-8-24**]. + +CXR [**2159-9-14**]: A right pectoral pacemaker power pack is +redemonstrated, with unchanged position of right atrial pacer +and right ventricular defibrillator leads on the single AP view. +Also old abandoned AICD and epicardial leads are unchanged, +projecting over the right and left heart, respectively. The +patient is status post CABG. Other lines projecting over the +patient are probably external to the patient. Right internal +jugular central venous catheter has been removed. +Moderate-to-severe cardiomegaly is relatively unchanged. There +is again increase in perihilar and bibasilar opacities, probably +representing pulmonary edema, although underlying infection +cannot be excluded. The upper lungs are relatively clear. +Appearance is not dissimilar to that seen on [**2159-8-24**]. The right +lateral sulcus is excluded, but there may be tiny bilateral +pleural +effusions. No pneumothorax is seen. + +[**2159-9-14**] WBC 11.2 Hb 10.8 Hct 36.6 Plts 300 +[**2159-9-14**] N 66.0 L 27.6 M 5.0 E 0.9 B 0.6 +[**2159-9-14**] PT 22.6 PTT 26.7 INR 2.1 +[**2159-9-14**] Gluc 105 BUN 19 Cr 1.0 Na 134 K 3.3 Cl 94 HCO3 26 +[**2159-9-14**] CK 98 TnT 0.05 +[**2159-9-14**] proBNP 8744 +[**2159-9-14**] Ca 8.8 Mg 2.0 +[**2159-9-14**] Digoxin 0.2 +[**2159-9-14**] UA neg + + +Brief Hospital Course: +61 year old male with a h/o CAD s/p MI and CABG in [**2144**], chronic +systolic heart failure (EF 20%), recurrent VT s/p ICD placement +and atrial fibrillation admitted now for recurrent ICD firing +after not taking home Sotalol for 2 weeks. +. +# Afib/VT: Pt has Afib, h/o VT, with several episodes of VT the +night PTA s/p shocks. On admission, pt was in Afib, with +occasional pacing, hemodynamically stable and rec'd Dilt for +rate control in the ED. On the morning of the 17th, he became +hemodynamically unstable with afib and RVR, and a code blue was +called during which the patient was intubated, shocked, and +administered a dose of amiodarone. On arrival to the CCU, the +patient's vital signs were 93, 101/52, 19, 88% on vent. He was +intubated, sedated, in sinus and intermittently paced and +hemodynamically stable. His labs returned with a K of 6.2 and +glucose of 48. Calcium gluconate, glucose, insulin, albuterol +and sodium bicarbonate were administered. Fentanyl and midazolam +were started for sedation. He was also continued on IV +amiodarone drip to maintain sinus rhythm, despite history of +hypothyroidism with amiodarone. He was stable after +self-extubation and was seen by EP who re-adjusted pacer +settings. He was started on amiodarone with good success and +transferred back to the floor on [**9-17**]. Pt remained in sinus +rhythm with intermittent pacing. Heparin gtt for anticoagulation +was eventually dc'd, and since pt has an elev INR at baseline, +it was decided not to start Coumadin as it would be difficult to +monitor. Pt was continued on Amiodarone 400mg daily to maintain +sinus rhythm as per EP recs. Home Sotalol has been dc'd. On +telemetry, pt continued to have frequent PVCs, NSVT. Also, pt +was started on Digoxin at cautious dose of 0.125mg every other +day since pt also on Amiodarone. +. +# Acute systolic heart failure: pt is volume overloaded per +exam, elev BNP and CXR, likely [**1-1**] to poor diet control and med +non compliance (dig level low). He improved with aggressive +diuresis with IV lasix, later switched to home Lasix dose. His +home simvastatin, midodrine, and spironolactone were continued. +Digoxin was temporarily held for renal failure but restarted at +a more cautious dose prior to discharge. The reason why the pt +was no on an ACE-I was not clear. Starting ACE-I during +admission was considered but decided to defer it to his +outpatient cardiologist. +. +# Hypothyroidism: [**1-1**] to Amiodarone toxicity, currently +asymptomatic. His home levothyroxine was continued. Will have +to recheck TSH since Amiodarone has been strated again, also +PFTs and LFTs. +. +# LLE Erythema and L heel ulcer: chronic, stable. No changes +indicating acute infection were seen. Pt was provided with wound +care. +. +# Insomnia: stable, home Ativan PRN and Ambien were continued. +. +# Depression: stable however likely contributing to his medical +non-compliance. Started on buproprion and Citalopram. SW was +following pt as well. +. +# Anemia: stable, at baseline, required no transfusions. Pt +could benefit from anemia work-up as outpatient. +. +# Elev INR: unclear etiology (perhaps [**1-1**] to hepatic congestion +from heart failure). Pt is off anticoagulation bc of h/o GIB. +Liver enzymes showed obstructive picture with nl ALT, AST +however elev Alk Phos and T bili of 3.1, however pt w/o abd +pain. Recent RUQ u/s negative, just an echogenic liver +consistent with fatty infiltration. + +# Pt was on a low Na cardiac diet, lytes were replted PRN. Pt +was on SC Heparin for DVT ppx. Pt was full code. + +Medications on Admission: +MEDICATIONS: +Sotalol 120 mg [**Hospital1 **] +Digoxin 125 mcg daily, 250mcg on alternative days +Ativan 2 mg QHS +Ambien 10 mg QHS +Levothyroxine 50 mcg daily +Midodrine 5 mg TID +Simvastatin 40 mg daily +Lasix 40mg daily +Spiranolactone 25mg daily +Bupoprion 50mg [**Hospital1 **] + + +Discharge Medications: +1. Midodrine 5 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +2. Levothyroxine 50 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Bupropion HCl 100 mg Tablet Sig: 0.5 Tablet PO BID (2 times a +day). +Disp:*30 Tablet(s)* Refills:*2* +4. Amiodarone 200 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +Disp:*60 Tablet(s)* Refills:*2* +5. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO EVERY OTHER DAY +(Every Other Day). +Disp:*15 Tablet(s)* Refills:*2* +7. Simvastatin 10 mg Tablet Sig: Four (4) Tablet PO DAILY +(Daily). +8. Spironolactone 25 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +9. Citalopram 20 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +Disp:*15 Tablet(s)* Refills:*2* +10. Ativan 2 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed for insomnia. +11. Ambien 10 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed for insomnia. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] Home Health Care + +Discharge Diagnosis: +ventricular tachycardia requiring external DC/CV +acute on chronic systolic heart failure + + +Discharge Condition: +good + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] because your ICD had fired multiple +times. It was noted that you were having frequent episodes of +irregular heart rate, likely due to the fact that you were not +taking one of your medications recently. During of one these +episodes, you became unresponsive, requiring shocking the heart, +placing a breathing tube to help your lungs breath and a brief +stay in the ICU. You subsequently recovered nicely from this +event and you were placed on optimal heart medications to help +your heart stay as regular as possible. + +Please make the following changes to your medications: +1. Start Amiodarone 400 mg DAILY +2. Start Digoxin 125 mcg EVERY OTHER DAY +3. Stop Digoxin 125 mcg and 250 mcg on alternative days +4. Start Citalopram 10 mg PO DAILY +5. Stop Sotalol +6. Start Buproprion 100mg twice a day + +Please seek immediate medical attention if you experience +frequent ICD firing, dizziness, fainting, palpatations, chest +pain, increased shortness of breath, high fevers or any other +concerning symptoms. + +Also, given your heart failure, please weigh yourself every +morning and call your PCP if weight goes up more than 3 lbs. +Adhere to 2 gm sodium diet and fluid restriction of 1500 cc per +day. + +Followup Instructions: +Please keep the following follow-up appointments: +[**2159-9-27**] 10:20a [**Doctor Last Name **]-CC7 + SC [**Hospital Ward Name **] CLINICAL CTR, [**Location (un) **] + CC7 CARDIOLOGY (SB) + +[**2159-9-27**] 09:30a DEVICE CLINIC (SB) + SC [**Hospital Ward Name **] CLINICAL CTR, [**Location (un) **] + DEVICE CLINIC (SB) + +[**2159-9-21**] 01:45p [**Last Name (LF) **],[**First Name8 (NamePattern2) 2671**] [**Last Name (NamePattern1) 31932**] + [**Hospital6 29**], [**Location (un) **] + [**Hospital 191**] MEDICAL UNIT + + + +Completed by:[**2159-9-22**]",40,2159-09-14 13:15:00,2159-09-19 18:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,AICD FIRING," +61 year old male with a h/o cad s/p mi and cabg in [**2144**], chronic +systolic heart failure (ef 20%), recurrent vt s/p icd placement +and atrial fibrillation admitted now for recurrent icd firing +after not taking home sotalol for 2 weeks. +. +# afib/vt: pt has afib, h/o vt, with several episodes of vt the +night pta s/p shocks. on admission, pt was in afib, with +occasional pacing, hemodynamically stable and recd dilt for +rate control in the ed. on the morning of the 17th, he became +hemodynamically unstable with afib and rvr, and a code blue was +called during which the patient was intubated, shocked, and +administered a dose of amiodarone. on arrival to the ccu, the +patients vital signs were 93, 101/52, 19, 88% on vent. he was +intubated, sedated, in sinus and intermittently paced and +hemodynamically stable. his labs returned with a k of 6.2 and +glucose of 48. calcium gluconate, glucose, insulin, albuterol +and sodium bicarbonate were administered. fentanyl and midazolam +were started for sedation. he was also continued on iv +amiodarone drip to maintain sinus rhythm, despite history of +hypothyroidism with amiodarone. he was stable after +self-extubation and was seen by ep who re-adjusted pacer +settings. he was started on amiodarone with good success and +transferred back to the floor on [**9-17**]. pt remained in sinus +rhythm with intermittent pacing. heparin gtt for anticoagulation +was eventually dcd, and since pt has an elev inr at baseline, +it was decided not to start coumadin as it would be difficult to +monitor. pt was continued on amiodarone 400mg daily to maintain +sinus rhythm as per ep recs. home sotalol has been dcd. on +telemetry, pt continued to have frequent pvcs, nsvt. also, pt +was started on digoxin at cautious dose of 0.125mg every other +day since pt also on amiodarone. +. +# acute systolic heart failure: pt is volume overloaded per +exam, elev bnp and cxr, likely [**1-1**] to poor diet control and med +non compliance (dig level low). he improved with aggressive +diuresis with iv lasix, later switched to home lasix dose. his +home simvastatin, midodrine, and spironolactone were continued. +digoxin was temporarily held for renal failure but restarted at +a more cautious dose prior to discharge. the reason why the pt +was no on an ace-i was not clear. starting ace-i during +admission was considered but decided to defer it to his +outpatient cardiologist. +. +# hypothyroidism: [**1-1**] to amiodarone toxicity, currently +asymptomatic. his home levothyroxine was continued. will have +to recheck tsh since amiodarone has been strated again, also +pfts and lfts. +. +# lle erythema and l heel ulcer: chronic, stable. no changes +indicating acute infection were seen. pt was provided with wound +care. +. +# insomnia: stable, home ativan prn and ambien were continued. +. +# depression: stable however likely contributing to his medical +non-compliance. started on buproprion and citalopram. sw was +following pt as well. +. +# anemia: stable, at baseline, required no transfusions. pt +could benefit from anemia work-up as outpatient. +. +# elev inr: unclear etiology (perhaps [**1-1**] to hepatic congestion +from heart failure). pt is off anticoagulation bc of h/o gib. +liver enzymes showed obstructive picture with nl alt, ast +however elev alk phos and t bili of 3.1, however pt w/o abd +pain. recent ruq u/s negative, just an echogenic liver +consistent with fatty infiltration. + +# pt was on a low na cardiac diet, lytes were replted prn. pt +was on sc heparin for dvt ppx. pt was full code. + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Acute kidney failure, unspecified; Paroxysmal ventricular tachycardia; Ulcer of heel and midfoot; Hyperosmolality and/or hypernatremia; Acquired coagulation factor deficiency; Other pulmonary insufficiency, not elsewhere classified; Chronic passive congestion of liver; Hyperpotassemia; Fitting and adjustment of other cardiac device; Personal history of noncompliance with medical treatment, presenting hazards to health; Congestive heart failure, unspecified; Old myocardial infarction; Atrial fibrillation; Other left bundle branch block; Other and unspecified hyperlipidemia; Unspecified acquired hypothyroidism; Depressive disorder, not elsewhere classified; Insomnia, unspecified; Anemia, unspecified; Aortocoronary bypass status]" +5060,119255.0,24311,2182-12-13,24310,193317.0,2182-10-11,Discharge summary,"Admission Date: [**2182-10-10**] Discharge Date: [**2182-10-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +alcoholic intoxication and heroin abuse + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Mr. [**Known lastname 24927**] is a 38 yo M with PMH of polysubstance abuse who +presents with acute alcoholic intoxication and heroin abuse. He +was found around [**Location (un) **] station and brought to [**Hospital1 18**]. On +arrival to [**Hospital1 18**], he reported also snorting heroin. +In the ED, VS: T 99 BP 98/73 HR 102 RR17 99%RA. He was initially +alert and awake, then became somnolent with RR of 6 and O2 sat +of 70%. He received naloxone with immediate awakening. RR +normalized and O2sat was normal. After several hours in [**Name (NI) **], pt +became increasingly agitated and received multiple doses of +valium for elevated CIWA scale, receiving total of 50mg PO. +Pt has frequent visits to [**Hospital1 18**]. Was recently admitted to MICU +Green on [**2182-10-5**]. At that time, seen by psychiatry who left +recommendation regarding administration of benzos as patient +frequently is administered high doses of benzodiazepines for +drug seeking behavior. + + +Past Medical History: +Per Discharge Summary ([**2182-6-18**]) +Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From previous DC summary. States he does not speak to any family +members, never married, no children. Homeless, states he does +not like shelters because he gets ""nervous around all the +people."" + +Family History: +Father with depression, OCD and alcoholism. Mother died of DM +complications + +Physical Exam: +VS: T 96 HR 86 BP 128/79 02sat 97% RR 12 +GEN: Disheveled, appears older than stated age +HEENT: EOMI, PERRL +NECK: Supple +CHEST: CTABL +CV: RRR, S1S2, no m/r/g +ABD:Soft, NT, ND +EXT: No c/c/e +Skin: Pruritic papular rash on trunk, groin, ankles bilaterally + +NEURO: speech slurred, unsteady gait, CN ii-xii intact; able to +answer questions appropriately +. + + +Pertinent Results: +[**2182-10-10**] 03:10PM GLUCOSE-83 UREA N-12 CREAT-0.8 SODIUM-143 +POTASSIUM-3.9 CHLORIDE-105 TOTAL CO2-26 ANION GAP-16 +[**2182-10-10**] 03:10PM estGFR-Using this +[**2182-10-10**] 03:10PM CALCIUM-9.0 PHOSPHATE-3.1 MAGNESIUM-1.8 +[**2182-10-10**] 03:10PM ASA-NEG ETHANOL-244* ACETMNPHN-NEG +bnzodzpn-POS barbitrt-NEG tricyclic-NEG +[**2182-10-10**] 03:10PM WBC-5.1# RBC-4.36* HGB-12.5* HCT-37.7* MCV-87 +MCH-28.6 MCHC-33.0 RDW-16.5* +[**2182-10-10**] 03:10PM NEUTS-33.2* BANDS-0 LYMPHS-58.8* MONOS-5.5 +EOS-1.6 BASOS-0.9 +[**2182-10-10**] 03:10PM HYPOCHROM-NORMAL ANISOCYT-NORMAL +POIKILOCY-NORMAL MACROCYT-NORMAL MICROCYT-NORMAL +POLYCHROM-NORMAL +[**2182-10-10**] 03:10PM PLT COUNT-239 + +Brief Hospital Course: +A/P: 38 yo M with PMH of ETOH abuse/withdrawal and multiple +hospitalizations presented with acute intoxication and heroin +use requiring naloxone in ED. +. +ETOH intoxication: ETOH level 244. Speech somewhat slurred on +exam. Pt admits to drinking rum and Listerine. Received Valium +50mg total in ED for CIWA >10. Had 5mg x 3 of Valium in the +MICU. Given thiamine, folate, MVI. Social work was contact[**Name (NI) **] and +paperwork for a section 35 was started. Pt left AMA before +paperwork could be completed (will take several days). Will need +to continue paperwork if pt returns in near future. + +Scabies: Pt was treated with permethrin cream and Ivermectin x +1. + +Pt left AMA before further care was done for pt. + + +Medications on Admission: +Per Discharge Summary ([**2182-6-18**]), Unknown Compliance +1. Folic Acid 1mg Daily +2. Thiamine 100mg Daily +3. MVT One tab Daily +4. Ferrous Sulfate 325mg One Tab Daily +5. Oxcarbazepine 300mg one tablet [**Hospital1 **] +6. Gabapentin 200mg PO Q8H +7. Prozac 40mg Once Daily + + +Discharge Medications: +left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +left AMA + +Discharge Condition: +left AMA + +Discharge Instructions: +left AMA + +Followup Instructions: +left AMA + + +Completed by:[**2182-10-11**]",63,2182-10-10 18:16:00,2182-10-11 13:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +a/p: 38 yo m with pmh of etoh abuse/withdrawal and multiple +hospitalizations presented with acute intoxication and heroin +use requiring naloxone in ed. +. +etoh intoxication: etoh level 244. speech somewhat slurred on +exam. pt admits to drinking rum and listerine. received valium +50mg total in ed for ciwa >10. had 5mg x 3 of valium in the +micu. given thiamine, folate, mvi. social work was contact[**name (ni) **] and +paperwork for a section 35 was started. pt left ama before +paperwork could be completed (will take several days). will need +to continue paperwork if pt returns in near future. + +scabies: pt was treated with permethrin cream and ivermectin x +1. + +pt left ama before further care was done for pt. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Opioid abuse, unspecified; Chronic hepatitis C without mention of hepatic coma; Obsessive-compulsive disorders; Anxiety state, unspecified; Cerebral degeneration, unspecified; Lack of housing; Scabies; Alcoholic polyneuropathy]" +5060,193317.0,24310,2182-10-11,24309,143525.0,2182-10-08,Discharge summary,"Admission Date: [**2182-10-7**] Discharge Date: [**2182-10-8**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +EtOH Intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Pt is a 38 yo male with a PMH significant for Etoh and Poly +substance abuse, Hep B, and Hep C. Pt was found down on the +street stating that he wanted to be run over by a car. Pt +recently was admitted to the MICU with EtOH intoxication +yesterday, pt left AMA. +In ED patient vitals were BP 93/58 - 156/89, HR 70-80s, T 98, +100% on 2L. Initially given 5mg haldol for agitation/combative +behavior, later given 10mg Valium PO. No access attained. +Complained of some tail bone pain which was worked up with plain +film of coccyx. ED was prepared for DC however pt reported +difficulty walking. + +Patient appears intoxicated and is not willing to answer +questions. Pt does not some abdomen, back, and extremity pain +globally. + +Past Medical History: +Per Discharge Summary ([**2182-6-18**]) +Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From previous DC summary. States he does not speak to any family +members, never married, no children. Homeless, states he does +not like shelters because he gets ""nervous around all the +people."" + +Family History: +Father with depression, OCD and alcoholism. Mother died of DM +complications + +Physical Exam: +T BP 121 HR 76 RR 20 O2sat 100% on RA +General - Resting comfortably in bed, no acute distress, Appears +intoxicated and is not interested in answering questions. +HEENT - Sclera anicteric, Lips dry +Neck - Supple, JVP not elevated, no LAD +Pulm - CTA bilaterally; no wheezes, rales, or rhonchi +CV - RRR, normal S1/S2; no murmurs, rubs, or gallops +Abdomen - Soft, Mild tenderness on palpation of abdomen +Ext - Warm, well perfused, radial and DP pulses 2+; no clubbing, +cyanosis or edema. Pain with palpation of lower extremity. +Neuro - Pt is not willing to participate with exam. Still +appears somewhat intoxicate, however mental status is improving. +Able to move all extremities. PERRL. EOMI. + + +Pertinent Results: +Radiograph Coccyx: Normal bony mineralization and alignment. No +evidence of fracture. Apparent mild sclerosis overlying the +right S1, S2 region is not appreciated on the more tilted views +and is likely artifactual. No evidence of fracture. Views of the +L5-S1 region do show some evidence of degenerative osteophyte +formation of the anterosuperior aspect of L5, probably some +posterior osteophytes of the L5-S1 disc interspace. + +Brief Hospital Course: +Pt is a 38 year old male with significant hx of +EtOH/Polysubstance abuse, who presented today with EtOH +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# Airway obstruction: Required a Code Blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. It resolved without intubation. Sats remained +normal. +. +#.EtOH Intoxication/Withdrawal: Received multiple doses of +ativan and valium. No objective signs of withdrawal by time of +his transfer to the MICU. Was also given MV and thiamine and +folate. +. +#. Scabies: Found to have extensive infection. Was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.Hep B/Hep C: Hep B infection cleared based on most recent +serologies. AST>ALT on recent liver function tests, most likely +was secondary to EtOH abuse. +. + +#. Code status: DNR/DNI confirmed 2 days prior with psych +. +Pt leave AMA on the morning of [**2182-10-8**]. + +Medications on Admission: +Per Discharge Summary ([**2182-6-18**]), Unknown Compliance +1. Folic Acid 1mg Daily +2. Thiamine 100mg Daily +3. MVT One tab Daily +4. Ferrous Sulfate 325mg One Tab Daily +5. Oxcarbazepine 300mg one tablet [**Hospital1 **] +6. Gabapentin 200mg PO Q8H +7. Prozac 40mg Once Daily + + +Discharge Medications: +left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Left AMA + + +Discharge Condition: +Left AMA + + +Discharge Instructions: +Left AMA + +Followup Instructions: +Left AMA + + + +Completed by:[**2182-10-9**]",3,2182-10-07 02:09:00,2182-10-08 09:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +pt is a 38 year old male with significant hx of +etoh/polysubstance abuse, who presented today with etoh +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# airway obstruction: required a code blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. it resolved without intubation. sats remained +normal. +. +#.etoh intoxication/withdrawal: received multiple doses of +ativan and valium. no objective signs of withdrawal by time of +his transfer to the micu. was also given mv and thiamine and +folate. +. +#. scabies: found to have extensive infection. was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.hep b/hep c: hep b infection cleared based on most recent +serologies. ast>alt on recent liver function tests, most likely +was secondary to etoh abuse. +. + +#. code status: dnr/dni confirmed 2 days prior with psych +. +pt leave ama on the morning of [**2182-10-8**]. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Suicidal ideation; Scabies; Other respiratory abnormalities; Obsessive-compulsive personality disorder; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing; Dysthymic disorder]" +5060,193317.0,24310,2182-10-11,24308,156497.0,2182-06-18,Discharge summary,"Admission Date: [**2182-6-13**] Discharge Date: [**2182-6-18**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 4365**] +Chief Complaint: +EtOH intoxication, hypertension. + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +Please see admission note for full details. Briefly, 37yoM w/ +h/o severe alcoholism with multiple admissions for withdrawal, +HBV, HCV, who was found passed out on [**6-14**] after drinking more +vodka that his usual amount. He also reported a recent h/o +fighting with a friend, resulting in R hand and substernal chest +pain. He was admitted to the MICU after being found to be in +acute withdrawal with HTN (SBP to 200s) and HR>100. + + +MICU Course: Mr. [**Known lastname 24927**] was started on folate, thiamine, MTV, +and valium prn for CIWA >10. He was found to have hypernatremia +and was treated with gentle IV hydration and drinking to thirst. +His musculoskeletal pain was managed with Percocet. Psychiatry +was consulted on day of admission to assess patient's capacity +to leave AMA. He initially agreed to voluntarily stay in the +hospital and completing a Section 35 on [**6-17**], as he did not meet +criteria for Section 12 for a psychiatric admission. He was +reported to manipulate nurses on floor asking for higher/more +frequent doses of Diazepam, with subjective complaints not +necessarily correlating to changes in vital signs. Patient was +reportedly [**Doctor Last Name **] high for tremor, anxiety, and reported +hallucinations with consistent stable vital signs. Psychiatry +recommended starting a standing Valium taper with CIWA for +objective signs of withdrawal only. + + +On arrival to the floor, the patient reported ""pain everywhere"", +and when elicited, focused on chest pain. He also reported +having ""withdrawal"", experiencing hot/cold flashes, skin +crawling, anxiety, and tremors. He wanted more pain medicine +(Percocet), and said that he would leave if he did not get +adequate pain medicine. + + +Past Medical History: +1. polysubstance abuse: ETOH, listerine, heroin, IVDU, +benzodiazepines +2. ethanol abuse, hx DTs and withdrawal seizures, intubated in +past +3. hepatitis C +4. hepatitis B +4. compartment syndrome RLE, [**2171**] +5. OCD and anxiety +6. depression with hx suicidal ideations and attempts +8. chronic bilateral hand swelling +9. severe peripheral neuropathy + +Social History: +He reports drinking [**2-8**] gallon vodka and listerine daily. +History of heroin, IVDU, benzodiazepine abuse, alcohol +withdrawal seizures and delerium tremens. +States he does not speak to any family members, never married, +no children. He is currently homeless and states he does not +like shelters because he gets ""nervous around all the people"". + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. +He reports his father had depression, alcoholism and +questionable OCD. + +Physical Exam: +VITALS: T: 97.7 BP 97/63 HR 68 RR 18 SpO2 97/RA +GENERAL: lying comfortably in bed, wearing cap, sheets pulled +tight over body, no obvious tremors +PSYCH: Combative +Pt refused all other components of PE + + +Pertinent Results: +Labs at Admission: +[**2182-6-13**] 06:50PM BLOOD WBC-4.4 RBC-4.61 Hgb-12.9* Hct-39.6* +MCV-86 MCH-27.9 MCHC-32.5 RDW-16.0* Plt Ct-158 +[**2182-6-13**] 06:50PM BLOOD Neuts-35.6* Lymphs-56.9* Monos-2.0 +Eos-4.7* Baso-0.8 +[**2182-6-13**] 06:50PM BLOOD Glucose-80 UreaN-8 Creat-0.8 Na-147* +K-4.2 Cl-109* HCO3-23 AnGap-19 +[**2182-6-14**] 07:09PM BLOOD ALT-55* AST-90* AlkPhos-98 TotBili-0.9 +[**2182-6-13**] 06:50PM BLOOD Calcium-8.6 Phos-4.0 Mg-1.9 +[**2182-6-13**] 06:50PM BLOOD ASA-NEG Ethanol-368* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Imaging Studies: + +Right hand plain film ([**6-14**]): +Abnormal curvilinear fragment identified just distal to the +first interphalangeal joint (volar aspect) as above. Please +correlate clinically, particularly on the volar aspect. This is +difficult to confirm given the lack of non- localizing symptoms. + +CXR ([**6-14**]): +Since [**2182-4-5**], lungs remain clear. The +cardiomediastinal silhouette and hilar contours are unchanged, +including minimal prominence of the ascending aorta, could be +related to systemic hypertension. There is no pleural effusion. + + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with a PMH s/f severe alcoholism with +several ICU admissions for management alchohol withdrawl in the +past, HCV, and HBV, admitted to the [**Hospital Unit Name 153**] for alcohol withdrawal. + +# Alcohol withdrawal: The patient was maintained on a CIWA scale +which required active intervention until the evening of [**6-16**]. +He was also continued on Folate, Thiamine and multivitamin. As +of the time of leaving the ICU, the patient had agreed to enter +Detox, but Psych/Social work had also started the Section 35 +process. The patient was called out to the floor after being +stable on decreasing doses of valium. He was started on a +standing valium taper when arriving on the floor. At time of +discharge, he had no signs of objective withdrawal. He was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# Hand pain: Questionable finger fracture on x-ray from recent +fighting. The patient was evaluated by hand and found to not +need operative intervention or splinting. Pain was controlled +with percocet while inpatient. + +# Hypernatremia: Attributed to dehydration from EtOH abuse. The +patient self corrected with PO intake and IV hydration. + +# Peripheral neuropathy: Attributed in the past to EtOH abuse. +Recent folate and B12 within normal limits. No hx of diabetes. +Pain was controlled with analgesics. + + +Medications on Admission: +(not taking any, but supposed to be on the following) +Prozac (pt thinks 40 mg daily) +Klonopin 1 mg TID +Trileptal (dose uncertain) +Remeron (dose uncertain) + +Discharge Medications: +1. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +2. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*0* +3. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +4. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +5. Oxcarbazepine 300 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +6. Gabapentin 100 mg Capsule Sig: Two (2) Capsule PO Q8H (every +8 hours). +Disp:*60 Capsule(s)* Refills:*0* +7. Prozac 40 mg Capsule Sig: One (1) Capsule PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses +Alcohol withdrawal +Right hand pain, no fracture + +Secondary Diagnoses +Anemia +Peripheral Neuropathy +Hepatitis B +Hepatitis C + + +Discharge Condition: +Patient afebrile with stable vital signs, discharged with plans +for alcohol detoxification program under section 35 + + +Discharge Instructions: +You have been admitted to the hospital for alcohol withdrawal. +You were discharged under section 35 with plans for +detoxification program. + +Please take all your medications as prescribed. The following +changes were made to your medication regimen. +1. Your klonopin was discontinued +2. Your remeron was discontinued +3. You were started on neurontin for pain +4. You were started on iron for your anemia +5. You were also started on thiamine, folate and multivitamins +for your nutritional health +Please keep all your follow up appointments as scheduled. + +Please seek medical attention or return to the emergency room if +you experience any fevers > 101 degrees, difficulty breathing, +chest pain, seizures, or any other concern symptoms. + +Followup Instructions: +Please make an appointment to see your primary care physician +[**Last Name (NamePattern4) **]. [**First Name (STitle) **]. He can be reached at [**Telephone/Fax (1) 61608**]. + + + +Completed by:[**2182-6-18**]",115,2182-06-14 20:51:00,2182-06-18 11:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with a pmh s/f severe alcoholism with +several icu admissions for management alchohol withdrawl in the +past, hcv, and hbv, admitted to the [**hospital unit name 153**] for alcohol withdrawal. + +# alcohol withdrawal: the patient was maintained on a ciwa scale +which required active intervention until the evening of [**6-16**]. +he was also continued on folate, thiamine and multivitamin. as +of the time of leaving the icu, the patient had agreed to enter +detox, but psych/social work had also started the section 35 +process. the patient was called out to the floor after being +stable on decreasing doses of valium. he was started on a +standing valium taper when arriving on the floor. at time of +discharge, he had no signs of objective withdrawal. he was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# hand pain: questionable finger fracture on x-ray from recent +fighting. the patient was evaluated by hand and found to not +need operative intervention or splinting. pain was controlled +with percocet while inpatient. + +# hypernatremia: attributed to dehydration from etoh abuse. the +patient self corrected with po intake and iv hydration. + +# peripheral neuropathy: attributed in the past to etoh abuse. +recent folate and b12 within normal limits. no hx of diabetes. +pain was controlled with analgesics. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Hyperosmolality and/or hypernatremia; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Unspecified essential hypertension; Anemia, unspecified; Pain in limb; Unarmed fight or brawl; Dysthymic disorder; Obsessive-compulsive disorders; Alcoholic polyneuropathy]" +5060,156497.0,24308,2182-06-18,24307,174823.0,2182-04-07,Discharge summary,"Admission Date: [**2182-4-4**] Discharge Date: [**2182-4-7**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 8263**] +Chief Complaint: +Alcohol intoxication +Altered mental status + +Major Surgical or Invasive Procedure: +Intubation [**2182-4-4**] +Extubation [**2182-4-5**] + +History of Present Illness: +Initial history and physical is as per ICU team. +.Mr. [**Known lastname 24927**] is a 37M with a history of severe alcoholism with +regular admissions to [**Hospital1 18**] for management of withdrawl, +complicated by DT's in the past, HBV, and HCV. Today at 2PM he +was found unresponsive by EMS at the T station, and brought to +the emergency department. +. +In the ED vitals were T=98.6, BP=111-134/79-96, HR=78-112, +RR=[**12-21**], O2sat=97%RA, FSBS 173. He was initially alert and +communicative, however, upon falling asleep, he became hypoxic +to 54% RA with an absent gag reflex, and was then intubated. +Sedated on a propofol drip, given 2mg Ativan given at 1442, 5mg +haldol, 2mg of narcan, and 1LNS. Right femoral CVL placed. +Labs were notable for an ETOH level of 280, and a leukocytosis +to 12,000. Otherwise tox screen was notable only for +benzodiazepines (patient was discharged on [**3-31**] for alcohol +intoxication, managed with BZDs). A head CT CT Cspine and CXR +were negative. + +Past Medical History: +1. polysubstance abuse: ETOH, listerine, heroin, IVDU, +benzodiazepines +2. hepatitis C +3. hepatitis B +4. compartment syndrome RLE, [**2171**] +5. OCD and anxiety +6. depression with hx suicidal ideations and attempts +7. ethanol abuse, hx DTs and withdrawal seizures, intubated in +past +8. chronic bilateral hand swelling +9. Severe peripheral neuropathy + + +Social History: +The patient has previously reported he is homeless and lives in +front of [**Location (un) 7073**] train station. He drinks regularly, often a +liter of listerine and a fifth of vodka and additional beer +every day. He has a history of IV heroin and smoking cocaine but +has insisted he quit both of those activities >10 years ago. He +also smoked cigarettes in the past but claims he stopped in +[**2167**]. + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +Admission PE: +Vitals: T: 96.6, HR 86, BP: 104/76 HR:75 +GEN: Sedated intubated +HEENT: Pupils pinpoint, equal and reactive bilaterally +NECK: No JVD, lymphadenopathy, trachea midline +CV: RRR, no M/R/G; 2+ radial, DP, and PT pulses bilaterally +PULM: Lungs CTAB, no W/R/R +ABD: Soft, NT, ND, +BS, no HSM, no masses +EXT: No C/C/E, no palpable cords +NEURO: Upon weaning propofol, opens eyes to voice, sits up, +moves all four extremities to command, babinskis downgoing, no +clonus. +SKIN: Lacerations at the left brow and cheek. + + +Pertinent Results: +Admission labs: + +[**2182-4-4**] 01:57PM BLOOD WBC-11.3*# RBC-4.55* Hgb-12.9* Hct-39.3* +MCV-86 MCH-28.3 MCHC-32.8 RDW-17.3* Plt Ct-426# +[**2182-4-4**] 01:57PM BLOOD Neuts-35.7* Bands-0 Lymphs-56.8* +Monos-3.2 Eos-3.5 Baso-0.9 +[**2182-4-4**] 01:57PM BLOOD Plt Ct-426# +[**2182-4-5**] 04:21AM BLOOD PT-13.0 PTT-28.5 INR(PT)-1.1 +[**2182-4-4**] 01:57PM BLOOD Glucose-129* UreaN-11 Creat-1.0 Na-142 +K-4.9 Cl-101 HCO3-32 AnGap-14 +[**2182-4-4**] 01:57PM BLOOD ALT-132* AST-110* AlkPhos-87 TotBili-0.2 +[**2182-4-4**] 01:57PM BLOOD Lipase-61* +[**2182-4-4**] 01:57PM BLOOD Calcium-9.1 Phos-4.4# Mg-2.2 +[**2182-4-4**] 01:57PM BLOOD ASA-NEG Ethanol-280* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG +[**2182-4-4**] 06:55PM BLOOD Type-ART pO2-545* pCO2-44 pH-7.40 +calTCO2-28 Base XS-2 Intubat-INTUBATED +[**2182-4-4**] 06:55PM BLOOD Lactate-1.7 + +[**2182-4-4**] CT head: 1. No intracranial hemorrhage or edema. +2. Unchanged depressed left nasal bone fracture. + +[**2182-4-5**] CT C spine: IMPRESSION: +No acute fracture. +NG tube appears to be looped within the pharynx. +. +CXR: +FINDINGS: In comparison with the study of [**4-4**], there is little +overall +change. Specifically, no evidence of acute pneumonia. Monitoring +and support +devices remain in place. + + + + + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with a PMH s/f severe alcoholism with +multiple ICU admissions for management of airway +protection/withdrawl in the past, HCV, and HBV, found +unresponsive in the setting of alcohol intoxication, intubated +for airway protection and hypoxia prior to recieving benzos in +ED, with incidentally diagnosed leukocytosis on routine labs. +. +#. Altered mental status: DDX includes ETOH intoxication with +level of 280, other toxic ingestion, intracranial bleed from his +fall, seizure from ETOH withdrawl vs. trauma. Head CT negative +for a bleed, CT Cspine was negative, and no clear +toxic-metabolic abnormalities on initial labs. His mental +status improved. +. +#. Hypoxia: In the setting of alcohol intoxication, likely +secondary to an aspiration event. CXR was negative for +pneumonia. Pt was extubated in the ICU. His O2 sasts remained +stable after that. +. +#. ETOH intoxication: Patient has a history of withdrawl +seizures. Also has severe anxiety at baseline, and is difficult +to monitor with a CIWA scale, as his subjective symptoms have +been unreliable. We used vital signs (hyperthermia, HTN, +Tachycardia)to monitor ETOH withdrawl, and wrote for diazepam as +needed. He was given MVI, thiamine, and folic acid. The +patient was often very agitated and anxious and demanded valium +despite not showing any vital sign evidence of withdrawal. SW +was consulted but the patient eloped before he could be seen. +As previously documented in previous OMR notes, this patient +should be section 35ed for his safety if he continues to come to +the hospital intoxicated. +. +# HCV/HBV: previous hx transaminitis, at baseline +. +# FEN: Diet was advanced to Regular s/p extubation. +. +# PPX: heparin SC +. +# Access: hx of difficulty with pIV and pt combative, femoral +CVL placed in ED upon arrival. Removed before discharge. +. +# Code: Full code +. +# Dispo: On [**2182-4-7**], the [**Name8 (MD) 228**] RN went to check on him and he +was found to have eloped from the hospital. +. +This discharge summary is signed by [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] as Dr. [**Name (STitle) 61607**] is no longer working at [**Hospital1 18**]. + +Medications on Admission: +None + +Discharge Medications: +Pt eloped + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH intoxication + + +Discharge Condition: +Fair. + +Discharge Instructions: +Pt eloped + +Followup Instructions: +Pt eloped + + +",72,2182-04-04 15:32:00,2182-04-07 12:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL;UNRESPONSIVE," +mr. [**known lastname 24927**] is a 37m with a pmh s/f severe alcoholism with +multiple icu admissions for management of airway +protection/withdrawl in the past, hcv, and hbv, found +unresponsive in the setting of alcohol intoxication, intubated +for airway protection and hypoxia prior to recieving benzos in +ed, with incidentally diagnosed leukocytosis on routine labs. +. +#. altered mental status: ddx includes etoh intoxication with +level of 280, other toxic ingestion, intracranial bleed from his +fall, seizure from etoh withdrawl vs. trauma. head ct negative +for a bleed, ct cspine was negative, and no clear +toxic-metabolic abnormalities on initial labs. his mental +status improved. +. +#. hypoxia: in the setting of alcohol intoxication, likely +secondary to an aspiration event. cxr was negative for +pneumonia. pt was extubated in the icu. his o2 sasts remained +stable after that. +. +#. etoh intoxication: patient has a history of withdrawl +seizures. also has severe anxiety at baseline, and is difficult +to monitor with a ciwa scale, as his subjective symptoms have +been unreliable. we used vital signs (hyperthermia, htn, +tachycardia)to monitor etoh withdrawl, and wrote for diazepam as +needed. he was given mvi, thiamine, and folic acid. the +patient was often very agitated and anxious and demanded valium +despite not showing any vital sign evidence of withdrawal. sw +was consulted but the patient eloped before he could be seen. +as previously documented in previous omr notes, this patient +should be section 35ed for his safety if he continues to come to +the hospital intoxicated. +. +# hcv/hbv: previous hx transaminitis, at baseline +. +# fen: diet was advanced to regular s/p extubation. +. +# ppx: heparin sc +. +# access: hx of difficulty with piv and pt combative, femoral +cvl placed in ed upon arrival. removed before discharge. +. +# code: full code +. +# dispo: on [**2182-4-7**], the [**name8 (md) 228**] rn went to check on him and he +was found to have eloped from the hospital. +. +this discharge summary is signed by [**first name4 (namepattern1) **] [**last name (namepattern1) **] as dr. [**name (stitle) 61607**] is no longer working at [**hospital1 18**]. + + ","PRIMARY: [Acute respiratory failure] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Acute pancreatitis; Alcohol withdrawal; Chronic hepatitis C without mention of hepatic coma; Depressive disorder, not elsewhere classified; Cocaine abuse, unspecified]" +5060,156497.0,24308,2182-06-18,24306,170299.0,2182-04-01,Discharge summary,"Admission Date: [**2182-3-30**] Discharge Date: [**2182-4-1**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2745**] +Chief Complaint: +alcohol intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +This is a 37 y.o. maln with history of alcoholism and HBV and +HCV presenting with presumed intoxication and c/o chest pain +complicated by development of profound agitation in the ED +requiring multiple sedating meds and restraints. The patient was +brought in by EMS complaining of chest pain and appearing +intoxicated. Initial vital signs were 98.1, 113/79, 100, 18, +100% on RA. He received 10 mg IV valium and intermittently +complained of abdominal, foot, and chest pain. He appeared +comfortable slept in the ED initially, though he was put in 4 pt +restraints for reasons that are somewhat unclear. Eventually, a +few hours after his admission, he became quite agitated +screaming for lorazepam and hydromorphone. He receieved another +10 mg diazepam to treat DT's but remained agitated and continued +to yell and struggle against restraints for the next two hours. +Went on to receive an additonal 20 mg diazepam then 10 mg +ziprasidone and finally 5 mg haloperidol. After this last +intervention the patient was once again somnolent and had a +right sided femoral CVL placed. +. +On arrival to the floor the patient is sedated and unresponsive. +Of note, he has history of multiple previous admissions to [**Hospital1 18**] +to EtOH withdrawal and with various drug seeking behaviors. + + +Past Medical History: +Polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + + +Social History: +Homeless. Active alchohol and heroin abuse. Drinks 1 bottle of +listerine and vodka daily and reports daily blackouts. Last +episode of sobriety was in [**2171**] for 9 months. He reports that he +has difficulty with detox because he has OCD and a fear of +people which makes shelters difficult for him. He is a +non-smoker + + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +Vitals: T: 97.1, HR 86, BP: 117/68 HR: 132 RR: 10 O2Sat: 98% RA + +GEN: Slightly disheveled middle aged male asleep in bed +HEENT: PERRL, sclera anicteric, mucous membranes appear dry, +poor dentition +NECK: No JVD, lymphadenopathy, trachea midline +CV: RRR, no M/R/G; 2+ radial, DP, and PT pulses bilaterally +PULM: Lungs CTAB, no W/R/R +ABD: Soft, NT, ND, +BS, no HSM, no masses +EXT: No C/C/E, no palpable cords +NEURO: Sedated, responds to painful stimuli, unable to converse +or answer questions. +SKIN: No jaundice, cyanosis, or gross dermatitis. No ecchymoses. + + + +Pertinent Results: +[**2182-3-31**] CXR: Lungs are clear. Heart size normal. No pleural +abnormality or evidence of central adenopathy. Lateral aspect of +the right lower chest is excluded from the study. + +[**2182-3-31**] 04:15AM BLOOD WBC-4.0 RBC-3.59* Hgb-9.9* Hct-30.4* +MCV-85 MCH-27.6 MCHC-32.6 RDW-17.1* Plt Ct-223 +[**2182-3-30**] 10:30PM BLOOD WBC-3.4* RBC-3.67* Hgb-10.5* Hct-30.4* +MCV-83 MCH-28.4 MCHC-34.4 RDW-16.3* Plt Ct-249 +[**2182-3-30**] 10:30PM BLOOD Neuts-49.3* Lymphs-36.1 Monos-6.2 +Eos-8.1* Baso-0.4 +[**2182-3-31**] 11:02AM BLOOD PT-13.0 PTT-27.3 INR(PT)-1.1 +[**2182-3-31**] 04:15AM BLOOD Glucose-96 UreaN-9 Creat-0.8 Na-140 K-3.7 +Cl-104 HCO3-32 AnGap-8 +[**2182-3-30**] 10:30PM BLOOD Glucose-85 UreaN-9 Creat-0.8 Na-144 +K-3.1* Cl-106 HCO3-25 AnGap-16 +[**2182-3-31**] 04:15AM BLOOD ALT-165* AST-151* LD(LDH)-243 AlkPhos-68 +Amylase-68 TotBili-0.3 +[**2182-3-30**] 10:30PM BLOOD CK(CPK)-500* +[**2182-3-30**] 10:30PM BLOOD cTropnT-<0.01 +[**2182-3-31**] 04:15AM BLOOD Phos-4.1 Mg-1.7 Iron-13* +[**2182-3-31**] 04:15AM BLOOD calTIBC-338 Ferritn-53 TRF-260 +[**2182-3-30**] 10:30PM BLOOD ASA-NEG Ethanol-111* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +37yoM hx alcoholism, multiple admits for detox and hx of +DTs/withdrawal szs, presenting with intoxication and agitation, +admitted to MICU for ethanol withdrawal and monitoring. +. +# ETOH intoxication/AMS: 37 y.o male with history of +polysubstance abues and multiple previous admits for detox/drug +seeking behavior. He presented intoxicated and became very +agitated in the ED requiring multiple sedating medications. The +patient was given a total of 40mg of valium in the ED. In the +ICU, he was given an additionl 5mg valium for anxiety. He was +also given thiamine, folate, and a multivitamin. Social work +was also contact[**Name (NI) **]. + The patient was transferred to the medicine floor and on the +am of [**4-1**] definitely appeared to be in clinical ETOH withdrawal +(despite his well-documented history of faking ETOH withdrawal +symptoms for benzos). The patient was aggressivley treated with +200 mg of valium in 9 hours and then determined to no longer +have any clinical evidence of ETOH withdrawal (involuntary +tremors). + However, the patient became very agitated and anxious. The +patient was again evaluated by the medicine attending and +clearly deemed to not be in ETOH withdrawal anymore. His +agitation and anxiety was now behavioral. + The patient's femoral line was removed with plan to monitor +overnight and d/c in am after shower with taxi voucher. + The patient shortly thereafter eloped from the hospital. + I would highly advocate that when the patient returns to [**Hospital1 18**] +that he be section 25'd. + + + +Medications on Admission: +. + +Discharge Medications: +None, patient eloped + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH withdrawal + +Patient eloped + +Discharge Condition: +Pt eloped + +Discharge Instructions: +Patient eloped + +Followup Instructions: +Patient eloped. +Would recommend section 25 when he eventually returns +intoxicated to ED + + +",78,2182-03-30 22:36:00,2182-04-01 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +37yom hx alcoholism, multiple admits for detox and hx of +dts/withdrawal szs, presenting with intoxication and agitation, +admitted to micu for ethanol withdrawal and monitoring. +. +# etoh intoxication/ams: 37 y.o male with history of +polysubstance abues and multiple previous admits for detox/drug +seeking behavior. he presented intoxicated and became very +agitated in the ed requiring multiple sedating medications. the +patient was given a total of 40mg of valium in the ed. in the +icu, he was given an additionl 5mg valium for anxiety. he was +also given thiamine, folate, and a multivitamin. social work +was also contact[**name (ni) **]. + the patient was transferred to the medicine floor and on the +am of [**4-1**] definitely appeared to be in clinical etoh withdrawal +(despite his well-documented history of faking etoh withdrawal +symptoms for benzos). the patient was aggressivley treated with +200 mg of valium in 9 hours and then determined to no longer +have any clinical evidence of etoh withdrawal (involuntary +tremors). + however, the patient became very agitated and anxious. the +patient was again evaluated by the medicine attending and +clearly deemed to not be in etoh withdrawal anymore. his +agitation and anxiety was now behavioral. + the patients femoral line was removed with plan to monitor +overnight and d/c in am after shower with taxi voucher. + the patient shortly thereafter eloped from the hospital. + i would highly advocate that when the patient returns to [**hospital1 18**] +that he be section 25d. + + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Anemia, unspecified; Lack of housing; Dysthymic disorder; Obsessive-compulsive disorders]" +5060,156497.0,24308,2182-06-18,24305,196749.0,2182-01-14,Discharge summary,"Admission Date: [**2182-1-4**] Discharge Date: [**2182-1-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 358**] +Chief Complaint: +Monitoring and treatment of EtOH withdrawal + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +This is a 37 year-old male with a history of alcoholism with +many admissions for intoxication, Hep B+C, polysubstance abuse, +and depression, who presents with intoxication. Pt reports that +he drank 1 liter of listerine today as well as a fifth of vodka +and then blackout. He was brought to the ED intoxicated but has +no recollection of how he got to the hospital. He complains of +pain at his left knee, but does not recall injuring it, and also +complains of chronic abdominal tenderness (but only when someone +presses on it). Denies nausea or vomiting. +. +In the ED, initial vitals were T 98.7, BP 123/87, HR 110, RR 16, +99% on RA. His BAL was 456. Serum tox was also positive for +benzos. Urine tox was negative. The plan was initially to +observe the patient overnight in the ED until he became sober. +However, around 7:30pm, the attending found the patient +tremulous, with HR in the 120-130s and complaining of withdrawal +symptoms. He was also having visual hallucinations of mice +running over his legs. Exam was only notable for some blood on +his pants over his left knee and a bump on his L forehead. Neuro +exam was non-focal. He remainted tachycardic with HR as high as +140s. He received a total of 15mg PO valium, 15mg IV valium, and +1mg IV ativan. Banana bag was started but PIV was not +functioning well. Admitted to the ICU for further monitoring. +. +On arrival to the [**Hospital Unit Name 153**], the patient is very anxious. He is no +longer experiencing visual hallucinations but reports that he is +delirious and does not know what is going on. He is adamant that +he is going to stop drinking this time and wants to go to a +detox facility-- apparently his best friend died one week ago +from drinking listerine. +. +ROS: He has been having frontal headaches for the past month +since being hit by an SUV one month ago. Has also had R-sided +chest pain at the site of impact from this MVC for the past +month. Has broken his nose several times and has difficulty +breathing from that. He also notes seeing spots in the periphery +of his vision recently. He complains of gait instability when +sober (less so when intoxicated) and also peripheral neuropathy +in his arms and legs. The patient denies any fevers, chills, +weight change, nausea, vomiting, abdominal pain, diarrhea, +constipation, melena, hematochezia, shortness of breath, +orthopnea, PND, lower extremity edema, cough, urinary frequency, +urgency, dysuria, lightheadedness, focal weakness, rash or skin +changes. + + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +Vitals: T: 98.7 BP: 138/106 HR: 132 RR: 17 O2Sat: 97% RA +GEN: Disheveled male, tremulous, anxious +HEENT: EOMI, PERRL, sclera anicteric, no nystagmus, no epistaxis +or rhinorrhea, MMM, OP Clear, poor dentition +NECK: No JVD, lymphadenopathy, trachea midline +COR: tachy, regular, no M/G/R, normal S1 S2, radial pulses +2 +PULM: Lungs CTAB, no W/R/R +ABD: Soft, diffusely tender to palpation, ND, +BS, no HSM, no +masses +EXT: No C/C/E, no palpable cords +MUSCULOSKELETAL: L knee swollen with 2 small healing lacerations +and echymossis over the patella, decreased range of motion (to +90 degrees), tender to palpation over the patella and medial +joint line +NEURO: A+O x 2 (person, year). CN II ?????? XII grossly intact. +Strength 5/5 in upper and lower extremities. Decreased sensation +grossly over lower extremities. Normal finger-to-nose. +SKIN: No jaundice, cyanosis, or gross dermatitis. No ecchymoses. + + + +Pertinent Results: +143 104 12 83 AGap=14 + +4.2 29 0.7 +ALT: 60 AP: 101 Tbili: 0.3 Alb: 4.6 +AST: 95 LDH: Dbili: TProt: 7.9 +[**Doctor First Name **]: Lip: 134 +Serum EtOH 456 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Comments: Positive Tricyclic Results Represent Potentially Toxic +Levels;Therapeutic Tricyclic Levels Will Typically Have Negative +Results + +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative + + 86 +5.8 12.3 313 + + 36.3 + N:40.2 L:53.0 M:3.8 E:1.6 Bas:1.4 +. + +FINDINGS: Lungs are clear without evidence lung nodules or +consolidations. +No pleural effusion. Cardiomediastinal silhouette is +unremarkable. Bone +structures are grossly normal. + +IMPRESSION: Normal examination without evidence of active or +inactive +tuberculosis. + +PPD positive with >20mm reaction + +Brief Hospital Course: +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of DTs/withdrawal seizures who +presents with intoxication followed by withdrawal. He received +30 mg Valium in the emergency room and was placed on a q1h CIWA +in the ICU. This was transitioned to a standing valium order per +his protocol on arrival to the floor. Social work was consulted. +MVI/thiamine/folate were given. He was monitored on telemetry. +. +His lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis C, in addition to +alcoholic hepatitis. He had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. This +improved and he was tolerating pos. +. +He noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +He was started on Klonopin for anxiety, similar to previous +outpatient dosing. He had a PPD placed, which was positive at +>20 mm, and a CXR was performed which was negative. + +Unfortunately, on the day of anticipated discharge to [**Hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (AMA, although he left without +risk/benefit). + +Medications on Admission: +none +chronically on klonopin, but it is frequently stolen on the +street. + +Discharge Medications: +none, AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +alcohol withdrawal/dependence +anxiety + + +Discharge Condition: +ambulating, no longer in withdrawal + + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + + +",155,2182-01-04 17:40:00,2182-01-14 10:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of dts/withdrawal seizures who +presents with intoxication followed by withdrawal. he received +30 mg valium in the emergency room and was placed on a q1h ciwa +in the icu. this was transitioned to a standing valium order per +his protocol on arrival to the floor. social work was consulted. +mvi/thiamine/folate were given. he was monitored on telemetry. +. +his lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis c, in addition to +alcoholic hepatitis. he had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. this +improved and he was tolerating pos. +. +he noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +he was started on klonopin for anxiety, similar to previous +outpatient dosing. he had a ppd placed, which was positive at +>20 mm, and a cxr was performed which was negative. + +unfortunately, on the day of anticipated discharge to [**hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (ama, although he left without +risk/benefit). + + ","PRIMARY: [Alcohol withdrawal delirium] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic pancreatitis; Chronic hepatitis C without mention of hepatic coma; Acute alcoholic hepatitis; Acute alcoholic intoxication in alcoholism, continuous; Pain in joint, lower leg; Lack of housing; Anxiety state, unspecified; Other, mixed, or unspecified drug abuse, unspecified; ]" +5060,148207.0,24313,2183-02-03,24309,143525.0,2182-10-08,Discharge summary,"Admission Date: [**2182-10-7**] Discharge Date: [**2182-10-8**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +EtOH Intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Pt is a 38 yo male with a PMH significant for Etoh and Poly +substance abuse, Hep B, and Hep C. Pt was found down on the +street stating that he wanted to be run over by a car. Pt +recently was admitted to the MICU with EtOH intoxication +yesterday, pt left AMA. +In ED patient vitals were BP 93/58 - 156/89, HR 70-80s, T 98, +100% on 2L. Initially given 5mg haldol for agitation/combative +behavior, later given 10mg Valium PO. No access attained. +Complained of some tail bone pain which was worked up with plain +film of coccyx. ED was prepared for DC however pt reported +difficulty walking. + +Patient appears intoxicated and is not willing to answer +questions. Pt does not some abdomen, back, and extremity pain +globally. + +Past Medical History: +Per Discharge Summary ([**2182-6-18**]) +Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From previous DC summary. States he does not speak to any family +members, never married, no children. Homeless, states he does +not like shelters because he gets ""nervous around all the +people."" + +Family History: +Father with depression, OCD and alcoholism. Mother died of DM +complications + +Physical Exam: +T BP 121 HR 76 RR 20 O2sat 100% on RA +General - Resting comfortably in bed, no acute distress, Appears +intoxicated and is not interested in answering questions. +HEENT - Sclera anicteric, Lips dry +Neck - Supple, JVP not elevated, no LAD +Pulm - CTA bilaterally; no wheezes, rales, or rhonchi +CV - RRR, normal S1/S2; no murmurs, rubs, or gallops +Abdomen - Soft, Mild tenderness on palpation of abdomen +Ext - Warm, well perfused, radial and DP pulses 2+; no clubbing, +cyanosis or edema. Pain with palpation of lower extremity. +Neuro - Pt is not willing to participate with exam. Still +appears somewhat intoxicate, however mental status is improving. +Able to move all extremities. PERRL. EOMI. + + +Pertinent Results: +Radiograph Coccyx: Normal bony mineralization and alignment. No +evidence of fracture. Apparent mild sclerosis overlying the +right S1, S2 region is not appreciated on the more tilted views +and is likely artifactual. No evidence of fracture. Views of the +L5-S1 region do show some evidence of degenerative osteophyte +formation of the anterosuperior aspect of L5, probably some +posterior osteophytes of the L5-S1 disc interspace. + +Brief Hospital Course: +Pt is a 38 year old male with significant hx of +EtOH/Polysubstance abuse, who presented today with EtOH +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# Airway obstruction: Required a Code Blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. It resolved without intubation. Sats remained +normal. +. +#.EtOH Intoxication/Withdrawal: Received multiple doses of +ativan and valium. No objective signs of withdrawal by time of +his transfer to the MICU. Was also given MV and thiamine and +folate. +. +#. Scabies: Found to have extensive infection. Was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.Hep B/Hep C: Hep B infection cleared based on most recent +serologies. AST>ALT on recent liver function tests, most likely +was secondary to EtOH abuse. +. + +#. Code status: DNR/DNI confirmed 2 days prior with psych +. +Pt leave AMA on the morning of [**2182-10-8**]. + +Medications on Admission: +Per Discharge Summary ([**2182-6-18**]), Unknown Compliance +1. Folic Acid 1mg Daily +2. Thiamine 100mg Daily +3. MVT One tab Daily +4. Ferrous Sulfate 325mg One Tab Daily +5. Oxcarbazepine 300mg one tablet [**Hospital1 **] +6. Gabapentin 200mg PO Q8H +7. Prozac 40mg Once Daily + + +Discharge Medications: +left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Left AMA + + +Discharge Condition: +Left AMA + + +Discharge Instructions: +Left AMA + +Followup Instructions: +Left AMA + + + +Completed by:[**2182-10-9**]",118,2182-10-07 02:09:00,2182-10-08 09:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +pt is a 38 year old male with significant hx of +etoh/polysubstance abuse, who presented today with etoh +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# airway obstruction: required a code blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. it resolved without intubation. sats remained +normal. +. +#.etoh intoxication/withdrawal: received multiple doses of +ativan and valium. no objective signs of withdrawal by time of +his transfer to the micu. was also given mv and thiamine and +folate. +. +#. scabies: found to have extensive infection. was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.hep b/hep c: hep b infection cleared based on most recent +serologies. ast>alt on recent liver function tests, most likely +was secondary to etoh abuse. +. + +#. code status: dnr/dni confirmed 2 days prior with psych +. +pt leave ama on the morning of [**2182-10-8**]. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Suicidal ideation; Scabies; Other respiratory abnormalities; Obsessive-compulsive personality disorder; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing; Dysthymic disorder]" +5060,174823.0,24307,2182-04-07,24302,184857.0,2181-11-20,Discharge summary,"Admission Date: [**2181-11-18**] Discharge Date: [**2181-11-20**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +ETOH Withdrawal + +Major Surgical or Invasive Procedure: +PICC placement ([**2181-11-19**]) + +History of Present Illness: +37 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions and ED evals returns with alcohol +intoxication and withdrawal. Presented to ED s/p unwitnessed +fall while intoxicated. Came in c/o L elbow and R hand pain. +Also with left supraorbital laceration that was repaired in the +ED. He reports currently drinking 1 bottle of Vodka and large +bottle of mouthwash daily. He has a hx of withdrawal seizures as +well as Section 35/Section 12 for ETOH abuse. +. +In the ED, initial VS: T96.6 HR 80 BP 108/73 RR16 100RA. He was +monitored overnight, but noted to be progressively more +tremulous and tachycardic. Also reported hallucinations. +Initially was threatening to leave AMA, but agreed to stay for +further treatment. Team unable to get PIVs so femoral line +placed for access. He received 50mg PO valium and 2mg of Ativan +IM since [**85**]:40 AM. +. +He was most recently admitted for EtOh withdrawal on [**11-9**] but +left AMA. He returned to the ED on [**11-13**] for intoxication and +was noted to have elevated amylase, lipase concerning for acute +pancreatitis. Again, pt signed out AMA. +. +On arrival to [**Hospital Unit Name 153**], patient was tremulous, complaining of pain +all over and felt like his ""skin was crawling."" Also reported +chronic abdominal pain over the last several months that he +attributed to excessive intake of listerine. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: Afebrile, BP 146/60, HR 114 RR 16 98%RA +GEN: Anxious, cooperative. +Neuro: AAO to person, place, time, situation. +- CN ii-xii intact +- motor [**6-11**] bilat upper/lower +- tremulous bilateral upper ext +- [**Last Name (un) 36**] to light touch intact +- toes downgoing bilaterally +- gait: not assessed as patient unsteady +HEENT: 1.5cm laceration with sutures and associated ecchymosis +and swelling of L eyebrow. Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non distended; mild tenderness throughout, hypoactive +BS +Ext: R femoral line C/D/I; no edema. good pulses +SKIN: No rashes + + +Pertinent Results: +[**2181-11-20**] 05:35AM BLOOD WBC-5.1 RBC-4.03* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.6 MCHC-34.1 RDW-14.8 Plt Ct-190 +[**2181-11-19**] 03:41AM BLOOD WBC-4.3 RBC-3.85* Hgb-11.6* Hct-33.3* +MCV-87 MCH-30.2 MCHC-34.8 RDW-15.5 Plt Ct-195 +[**2181-11-18**] 02:31PM BLOOD WBC-6.1 RBC-4.43* Hgb-13.2* Hct-37.8* +MCV-85 MCH-29.9 MCHC-35.0 RDW-16.0* Plt Ct-272# +[**2181-11-18**] 02:31PM BLOOD Neuts-32.6* Lymphs-57.1* Monos-6.0 +Eos-3.2 Baso-1.2 +[**2181-11-20**] 05:35AM BLOOD PT-12.0 PTT-33.4 INR(PT)-1.0 +[**2181-11-20**] 05:35AM BLOOD Glucose-93 UreaN-8 Creat-0.6 Na-136 K-3.8 +Cl-104 HCO3-24 AnGap-12 +[**2181-11-20**] 05:35AM BLOOD ALT-44* AST-72* LD(LDH)-286* +[**2181-11-20**] 05:35AM BLOOD Calcium-8.4 Phos-3.4 Mg-1.9 +[**2181-11-18**] 02:31PM BLOOD ASA-NEG Ethanol-137* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +36M with EtOH dependence and frequent admissions for EtOH +intoxication presents s/p fall with EtOH withdrawal. + +1. Alcohol withdrawal: No hypertension or tachycardia this +morning. Slightly agitated and with slight upper extremity +tremor. Has history of hx of DTs and w/d seizures. Patient was +treated with CIWA scale per prior admissions. On hospital day +3, patient signed out AMA. + +2. Fall: Patient with unwitnessed fall. Radiographs negative +for fracture. + +3. Abdominal pain: [**Month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of LFTs. + +4. Alcoholic liver disease: AST/ALT improving. No stigmata of +liver disease by physical exam. [**Doctor First Name **]/lipase normal. Also has +history of hepatitis B/C. + +5. Anemia: Normocytic anemia, at baseline. + +6. PPx: Patient treated with heparin SQ for dvt prophylaxis. + +7. Access: Patient with femoral CVL placed in ED. PICC placed +during admission, which was removed when patient signed out AMA. + +8. Dispo: Patient signed out AMA. + +Medications on Admission: +None + +Discharge Medications: +1. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +EtOH withdrawal + + +Discharge Condition: +Patient leaving against medical advice. + + +Discharge Instructions: +You were admitted for alcohol withdrawal and received +benzodiazepines to manage your withdrawal. We recommended +transfer to the regular medical floor from the ICU for continued +management of your withdrawal symptoms, but you have decided to +leave against our medical advice. + +Followup Instructions: +Please follow up with your primary care doctor within the next +few days. You should also seek care for substance abuse. + + + +Completed by:[**2181-11-20**]",138,2181-11-18 06:42:00,2181-11-20 12:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALTERED MENTAL STATUS," +36m with etoh dependence and frequent admissions for etoh +intoxication presents s/p fall with etoh withdrawal. + +1. alcohol withdrawal: no hypertension or tachycardia this +morning. slightly agitated and with slight upper extremity +tremor. has history of hx of dts and w/d seizures. patient was +treated with ciwa scale per prior admissions. on hospital day +3, patient signed out ama. + +2. fall: patient with unwitnessed fall. radiographs negative +for fracture. + +3. abdominal pain: [**month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of lfts. + +4. alcoholic liver disease: ast/alt improving. no stigmata of +liver disease by physical exam. [**doctor first name **]/lipase normal. also has +history of hepatitis b/c. + +5. anemia: normocytic anemia, at baseline. + +6. ppx: patient treated with heparin sq for dvt prophylaxis. + +7. access: patient with femoral cvl placed in ed. picc placed +during admission, which was removed when patient signed out ama. + +8. dispo: patient signed out ama. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Open wound of forehead, without mention of complication; Unspecified fall; Chronic hepatitis C without mention of hepatic coma; Lack of housing; Anemia, unspecified; Acute alcoholic hepatitis; Alcoholic gastritis, without mention of hemorrhage; Hypovolemia]" +5060,174823.0,24307,2182-04-07,24303,197750.0,2181-12-11,Discharge summary,"Admission Date: [**2181-12-7**] Discharge Date: [**2181-12-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 8487**] +Chief Complaint: +ETOH Withdrawal, Chest, Abdominal, Arm and Hand Pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +37yoM with hx of polysubstance abuse, frequent ICU admissions +and ED evals returns with alcohol intoxication and withdrawal. +Pt reports currently using ETOH, and presenting for pain from a +reported trauma approx 4 days ago at which time the patient +reports being hit by a SUV. He states he signed out AMA from the +[**Hospital1 3278**] ICU after this accident. Pt with a hx of withdrawal +seizures as well as Section 35/Section 12 for ETOH abuse. The +patient reports being acutely intoxicated currently, and most +recently, drinking Listerine this am. Today the patient was +found lying next to [**Company 2486**] where EMS was called and we +has brought to the ED. Since leaving [**Hospital1 3278**] he has spent the past +few days at [**Location (un) 7073**] Station, drinking Vodka during the day and +Listerine at night ""to prevent seizures"". He believes his last +seizure occurred three weeks ago. He notes pain all over his +body - esp in his hands, chest, abdomen and legs. +. +In the ED, initial VS 98.3 120/88 116 16 100%2L: In the E.D. he +received Morphine 6mg, Valium 50mg, Gabapentin 600mg, Toradol +30mg, 1 banana bag and 2 additional L of NS. He was monitored, +but noted to be progressively more tremulous, tachycardic and +reporting visual hallucinations. +. +Of note the pt has had recent admissions for EtOh withdrawal on +[**11-9**] but left AMA. He returned to the ED on [**11-13**] for +intoxication and was noted to have elevated amylase, lipase +concerning for acute pancreatitis. Again, pt signed out AMA. The +pt was admitted on [**11-18**], again for acute EtOH withdrwal, and +signed out AMA on [**11-20**]. +. +On arrival to [**Hospital Unit Name 153**]: Pt tremulous, anxious, tachy to 110s, with +some visual hallucinations, however not hypertensive or febrile. +Pt denies fever, + chills, headache. Admits to chronic abdominal +pain of [**8-14**] months duration. Pt also admits to chest pain of one +weeks duration since being hit by a car. Pt also noted recent +episodes of epistaxis, although none within the past few days. +. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C (Diagnosed around [**2163**], Never treated) +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 98.7 113/77 89 98 3LNC +GEN: Anxious, cooperative. Alert to date, name but not to +location +HEENT: PERRLA Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non-distended; mild tenderness throughout, hypoactive +BS +Ext: 1+ Bilateral upper extremity edema. good pulses +SKIN: No rashes +Neuro: AOx2, (not location), CN II-XII intact, Motor [**6-11**] bilat, +Tremulous bilateral upper ext + + +Pertinent Results: +Admission labs +[**2181-12-7**] 05:35PM BLOOD WBC-3.5* RBC-3.97* Hgb-11.8* Hct-34.7* +MCV-87 MCH-29.7 MCHC-34.0 RDW-15.4 Plt Ct-308# +[**2181-12-7**] 05:35PM BLOOD Neuts-33.4* Bands-0 Lymphs-57.1* +Monos-5.0 Eos-3.2 Baso-1.3 +[**2181-12-7**] 05:35PM BLOOD PT-13.3 PTT-29.8 INR(PT)-1.1 +[**2181-12-7**] 05:35PM BLOOD Glucose-198* UreaN-7 Creat-0.8 Na-143 +K-3.8 Cl-102 HCO3-25 AnGap-20 +[**2181-12-7**] 05:35PM BLOOD ALT-52* AST-101* CK(CPK)-359* AlkPhos-83 +[**2181-12-7**] 05:35PM BLOOD Lipase-135* +[**2181-12-7**] 05:35PM BLOOD Albumin-4.3 +[**2181-12-9**] 04:24AM BLOOD TSH-3.1 +[**2181-12-7**] 05:35PM BLOOD ASA-NEG Ethanol-396* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +[**2181-12-7**]: CXR IMPRESSION: No acute cardiopulmonary abnormality. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with ETOH dependence and frequent +admissions for EtOH intoxication who presents with EtOH +withdrawal and global pain. +. +# EtoH Withdrawal:On admission, the pt was A0x2. Throughout his +ICU stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. CIWAs 16-29. However, it +is also notable that he knows how to manipulate the CIWA and +would frequently do so in order to get increasing amounts of +benzodiazepines. On [**12-11**], his CIWA was discontinued and he was +told he would be transferred to the floor at which point he +signout AMA. While here, he was given thiamine, MVI, folate and +PRN electrolytes. +. +# Abdominal and Chest pain: DDx includes recent trauma (although +nothing apparent on exam), acute EtOh hepatitis, pancreatitis, +though minimal elevation of LFTs. Less likely cardiac given +reproducible nature, and unchanged EKG. No fever or leukocytosis +at this time. Lipase slightly increased from [**11-18**] (135 from +56). No evidence of ascites on recent Abd U/S. Troponins were +trended. He was given oxycodone 5-10mg Q 4hrs PRN. +. +# Alcoholic liver disease: AST/ALT elevated in 2:1 ratio, this +is his baseline. No stigmata of liver disease by physical exam. +Lipase 135 normal. INR 1.1. No scopes in [**Hospital1 **] records. LFTs and +coags were monitored. +. +# Anemia - Iron deficiency anemia baseline per [**11-9**] labs with +Ferritin of 11. Hct drop from 34 to 28 in setting of 3L IVF upon +admission. No active signs of bleeding, likely diluational. Hct +was monitored, pt was given po iron, folate and thiamine. + + +Medications on Admission: +None + +Discharge Medications: +Pt was not given medications nor discharge instructions as he +left AMA on the morning of [**2181-12-11**]. + +Discharge Disposition: +Home + +Discharge Diagnosis: +. + +Discharge Condition: +. + +Discharge Instructions: +. + +Followup Instructions: +. + + +Completed by:[**2182-1-10**]",117,2181-12-08 19:58:00,2181-12-11 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with etoh dependence and frequent +admissions for etoh intoxication who presents with etoh +withdrawal and global pain. +. +# etoh withdrawal:on admission, the pt was a0x2. throughout his +icu stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. ciwas 16-29. however, it +is also notable that he knows how to manipulate the ciwa and +would frequently do so in order to get increasing amounts of +benzodiazepines. on [**12-11**], his ciwa was discontinued and he was +told he would be transferred to the floor at which point he +signout ama. while here, he was given thiamine, mvi, folate and +prn electrolytes. +. +# abdominal and chest pain: ddx includes recent trauma (although +nothing apparent on exam), acute etoh hepatitis, pancreatitis, +though minimal elevation of lfts. less likely cardiac given +reproducible nature, and unchanged ekg. no fever or leukocytosis +at this time. lipase slightly increased from [**11-18**] (135 from +56). no evidence of ascites on recent abd u/s. troponins were +trended. he was given oxycodone 5-10mg q 4hrs prn. +. +# alcoholic liver disease: ast/alt elevated in 2:1 ratio, this +is his baseline. no stigmata of liver disease by physical exam. +lipase 135 normal. inr 1.1. no scopes in [**hospital1 **] records. lfts and +coags were monitored. +. +# anemia - iron deficiency anemia baseline per [**11-9**] labs with +ferritin of 11. hct drop from 34 to 28 in setting of 3l ivf upon +admission. no active signs of bleeding, likely diluational. hct +was monitored, pt was given po iron, folate and thiamine. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Lack of housing]" +5060,174823.0,24307,2182-04-07,24304,135773.0,2181-12-14,Discharge summary,"Admission Date: [**2181-12-12**] Discharge Date: [**2181-12-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +abdominal pain, alcohol withdrawal + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +HPI: 37 yo M with PMH of alcohol abuse with many admissions for +intoxication, hepatitis B and C who was brought in by the police +after being found intoxicated. He originally did not complain of +any pain or other problems. Of note, he was left AMA [**2181-12-11**] +from the [**Hospital Unit Name 153**] after admission for intoxication and concern for +pancreatitis given elevated amlyase and lipase. +. +In the ED, his initial vital signs were T 100.3, BP 106/45, HR +108, RR 18, O2sat 98% RA. He was found on exam to be very tender +to palpation of his abdomen with rebound and guarding. He was +pan-scanned given these findings. He was given 2L NS. He was +placed in a C collar for spine protection. He was given +levofloxacin 750mg IV x1 prior to imaging because he complained +of cough and had the low grade temp. He was given 5mg IV haldol +and written for 5mg PO valium but it is unclear if he received +this or not. +. +Currently, he is not answering very many questions. Obviously +intoxicated and sleeping. Denies pain. Could not tell me how +much alcohol he had today or what he drank. He usually admits to +vodka and listerine as his drinks of choice. +. + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +BP 105/67 HR 82 RR13 95% RA +Gen: somnolent man, disheaveled, NAD +HEENT: pupils 2-3mm, PERRLA, anicteric sclera, facial laceration +above R eyebrow, MM dry with lip cracking. Neck with JVD or LAD. +CV: RRR, no murmurs, rubs, gallops +Pulm: Clear to auscultation bilaterally +Abd: normoactive BS, soft, nondistended, tender to deep +palpation throughout. + guarding, tender with percussion. + +ecchymosis in RLQ +Ext: no edema, no rashes, 2+ pulses peripherally +Neuro: PERRLA. Responds to occasional questions, not following +commands. No tremors, no clonus. Opens eyes to verbal stimulus. +2+ patellar reflexes. + +Pertinent Results: +[**2181-12-12**] 08:30PM BLOOD WBC-3.7* RBC-3.34* Hgb-10.0* Hct-29.2* +MCV-88 MCH-30.0 MCHC-34.3 RDW-15.8* Plt Ct-316 +[**2181-12-12**] 08:30PM BLOOD Neuts-45.0* Lymphs-47.7* Monos-3.9 +Eos-2.2 Baso-1.1 +[**2181-12-12**] 08:30PM BLOOD Glucose-76 UreaN-11 Creat-1.0 Na-143 +K-4.1 Cl-106 HCO3-29 AnGap-12 +[**2181-12-12**] 08:30PM BLOOD ALT-39 AST-82* AlkPhos-69 Amylase-159* +TotBili-0.2 +[**2181-12-12**] 08:30PM BLOOD Lipase-80* +[**2181-12-12**] 08:30PM BLOOD cTropnT-<0.01 +[**2181-12-12**] 08:30PM BLOOD ASA-NEG Ethanol-304* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG +[**2181-12-12**] 08:41PM BLOOD Lactate-1.2 +. +[**2181-12-12**] CT Head: 1. No acute intracranial hemorrhage. 2. +Cerebellar atrophy. +. +[**2181-12-12**] CT C-Spine: No acute fracture or malalignment of the +cervical spine. Mild degenerative changes. +. +[**2181-12-12**] X-ray L elbow: No acute fracture or dislocation. Old +healed left humeral shaft fracture partially visualized. +. + +[**2181-12-12**] CXR: No acute cardiopulmonary process. +. +[**2181-12-12**] Abd/Pelvis CT: No CT evidence of pancreatitis or acute +intra-abdominal or pelvic findings. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. He had elevated amylase and lipase concerning for +pancreatitis. A CT of his abdomen was negative for any +abdominal pathology. Initially he was somnolent but on the day +after admission he became more arousable. He received +approximately 200mg of PO Valium over a 24 hour period for +alcohol withdrawal. He continued to complain of abdominal pain +but his abdomen was benign and CT did not show any pathology. +He was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. His LFTs were mildly elevated +consistent with alcoholic disease. He was given multivitamins, +thiamine and folate. His electrolytes were monitored; however +blood draws were difficult due to poor access. Social work and +addiction services were consulted. He was referred the [**Hospital1 **] +Stabilization Program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. An attempt was made to +transfer him to the floor and when he was told this, he held his +breath and O2 sats dropped to the 70s and he was tachycardic. +. +On [**2181-12-14**] he left the hospital against medical advice. He was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + +Medications on Admission: +none + +Discharge Medications: +pt left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Alcohol Withdrawal + +Discharge Condition: +fair + +Discharge Instructions: +Pt left AMA prior to receiving instructions. + +Followup Instructions: +Pt left AMA prior to receiving instructions. + + +",114,2181-12-12 22:29:00,2181-12-14 12:48:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,PANCREATITIS," +mr. [**known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. he had elevated amylase and lipase concerning for +pancreatitis. a ct of his abdomen was negative for any +abdominal pathology. initially he was somnolent but on the day +after admission he became more arousable. he received +approximately 200mg of po valium over a 24 hour period for +alcohol withdrawal. he continued to complain of abdominal pain +but his abdomen was benign and ct did not show any pathology. +he was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. his lfts were mildly elevated +consistent with alcoholic disease. he was given multivitamins, +thiamine and folate. his electrolytes were monitored; however +blood draws were difficult due to poor access. social work and +addiction services were consulted. he was referred the [**hospital1 **] +stabilization program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. an attempt was made to +transfer him to the floor and when he was told this, he held his +breath and o2 sats dropped to the 70s and he was tachycardic. +. +on [**2181-12-14**] he left the hospital against medical advice. he was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Alcoholic liver damage, unspecified; Lack of housing]" +5060,174823.0,24307,2182-04-07,24305,196749.0,2182-01-14,Discharge summary,"Admission Date: [**2182-1-4**] Discharge Date: [**2182-1-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 358**] +Chief Complaint: +Monitoring and treatment of EtOH withdrawal + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +This is a 37 year-old male with a history of alcoholism with +many admissions for intoxication, Hep B+C, polysubstance abuse, +and depression, who presents with intoxication. Pt reports that +he drank 1 liter of listerine today as well as a fifth of vodka +and then blackout. He was brought to the ED intoxicated but has +no recollection of how he got to the hospital. He complains of +pain at his left knee, but does not recall injuring it, and also +complains of chronic abdominal tenderness (but only when someone +presses on it). Denies nausea or vomiting. +. +In the ED, initial vitals were T 98.7, BP 123/87, HR 110, RR 16, +99% on RA. His BAL was 456. Serum tox was also positive for +benzos. Urine tox was negative. The plan was initially to +observe the patient overnight in the ED until he became sober. +However, around 7:30pm, the attending found the patient +tremulous, with HR in the 120-130s and complaining of withdrawal +symptoms. He was also having visual hallucinations of mice +running over his legs. Exam was only notable for some blood on +his pants over his left knee and a bump on his L forehead. Neuro +exam was non-focal. He remainted tachycardic with HR as high as +140s. He received a total of 15mg PO valium, 15mg IV valium, and +1mg IV ativan. Banana bag was started but PIV was not +functioning well. Admitted to the ICU for further monitoring. +. +On arrival to the [**Hospital Unit Name 153**], the patient is very anxious. He is no +longer experiencing visual hallucinations but reports that he is +delirious and does not know what is going on. He is adamant that +he is going to stop drinking this time and wants to go to a +detox facility-- apparently his best friend died one week ago +from drinking listerine. +. +ROS: He has been having frontal headaches for the past month +since being hit by an SUV one month ago. Has also had R-sided +chest pain at the site of impact from this MVC for the past +month. Has broken his nose several times and has difficulty +breathing from that. He also notes seeing spots in the periphery +of his vision recently. He complains of gait instability when +sober (less so when intoxicated) and also peripheral neuropathy +in his arms and legs. The patient denies any fevers, chills, +weight change, nausea, vomiting, abdominal pain, diarrhea, +constipation, melena, hematochezia, shortness of breath, +orthopnea, PND, lower extremity edema, cough, urinary frequency, +urgency, dysuria, lightheadedness, focal weakness, rash or skin +changes. + + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +Vitals: T: 98.7 BP: 138/106 HR: 132 RR: 17 O2Sat: 97% RA +GEN: Disheveled male, tremulous, anxious +HEENT: EOMI, PERRL, sclera anicteric, no nystagmus, no epistaxis +or rhinorrhea, MMM, OP Clear, poor dentition +NECK: No JVD, lymphadenopathy, trachea midline +COR: tachy, regular, no M/G/R, normal S1 S2, radial pulses +2 +PULM: Lungs CTAB, no W/R/R +ABD: Soft, diffusely tender to palpation, ND, +BS, no HSM, no +masses +EXT: No C/C/E, no palpable cords +MUSCULOSKELETAL: L knee swollen with 2 small healing lacerations +and echymossis over the patella, decreased range of motion (to +90 degrees), tender to palpation over the patella and medial +joint line +NEURO: A+O x 2 (person, year). CN II ?????? XII grossly intact. +Strength 5/5 in upper and lower extremities. Decreased sensation +grossly over lower extremities. Normal finger-to-nose. +SKIN: No jaundice, cyanosis, or gross dermatitis. No ecchymoses. + + + +Pertinent Results: +143 104 12 83 AGap=14 + +4.2 29 0.7 +ALT: 60 AP: 101 Tbili: 0.3 Alb: 4.6 +AST: 95 LDH: Dbili: TProt: 7.9 +[**Doctor First Name **]: Lip: 134 +Serum EtOH 456 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Comments: Positive Tricyclic Results Represent Potentially Toxic +Levels;Therapeutic Tricyclic Levels Will Typically Have Negative +Results + +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative + + 86 +5.8 12.3 313 + + 36.3 + N:40.2 L:53.0 M:3.8 E:1.6 Bas:1.4 +. + +FINDINGS: Lungs are clear without evidence lung nodules or +consolidations. +No pleural effusion. Cardiomediastinal silhouette is +unremarkable. Bone +structures are grossly normal. + +IMPRESSION: Normal examination without evidence of active or +inactive +tuberculosis. + +PPD positive with >20mm reaction + +Brief Hospital Course: +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of DTs/withdrawal seizures who +presents with intoxication followed by withdrawal. He received +30 mg Valium in the emergency room and was placed on a q1h CIWA +in the ICU. This was transitioned to a standing valium order per +his protocol on arrival to the floor. Social work was consulted. +MVI/thiamine/folate were given. He was monitored on telemetry. +. +His lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis C, in addition to +alcoholic hepatitis. He had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. This +improved and he was tolerating pos. +. +He noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +He was started on Klonopin for anxiety, similar to previous +outpatient dosing. He had a PPD placed, which was positive at +>20 mm, and a CXR was performed which was negative. + +Unfortunately, on the day of anticipated discharge to [**Hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (AMA, although he left without +risk/benefit). + +Medications on Admission: +none +chronically on klonopin, but it is frequently stolen on the +street. + +Discharge Medications: +none, AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +alcohol withdrawal/dependence +anxiety + + +Discharge Condition: +ambulating, no longer in withdrawal + + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + + +",83,2182-01-04 17:40:00,2182-01-14 10:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of dts/withdrawal seizures who +presents with intoxication followed by withdrawal. he received +30 mg valium in the emergency room and was placed on a q1h ciwa +in the icu. this was transitioned to a standing valium order per +his protocol on arrival to the floor. social work was consulted. +mvi/thiamine/folate were given. he was monitored on telemetry. +. +his lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis c, in addition to +alcoholic hepatitis. he had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. this +improved and he was tolerating pos. +. +he noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +he was started on klonopin for anxiety, similar to previous +outpatient dosing. he had a ppd placed, which was positive at +>20 mm, and a cxr was performed which was negative. + +unfortunately, on the day of anticipated discharge to [**hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (ama, although he left without +risk/benefit). + + ","PRIMARY: [Alcohol withdrawal delirium] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic pancreatitis; Chronic hepatitis C without mention of hepatic coma; Acute alcoholic hepatitis; Acute alcoholic intoxication in alcoholism, continuous; Pain in joint, lower leg; Lack of housing; Anxiety state, unspecified; Other, mixed, or unspecified drug abuse, unspecified; ]" +5060,174823.0,24307,2182-04-07,24306,170299.0,2182-04-01,Discharge summary,"Admission Date: [**2182-3-30**] Discharge Date: [**2182-4-1**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2745**] +Chief Complaint: +alcohol intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +This is a 37 y.o. maln with history of alcoholism and HBV and +HCV presenting with presumed intoxication and c/o chest pain +complicated by development of profound agitation in the ED +requiring multiple sedating meds and restraints. The patient was +brought in by EMS complaining of chest pain and appearing +intoxicated. Initial vital signs were 98.1, 113/79, 100, 18, +100% on RA. He received 10 mg IV valium and intermittently +complained of abdominal, foot, and chest pain. He appeared +comfortable slept in the ED initially, though he was put in 4 pt +restraints for reasons that are somewhat unclear. Eventually, a +few hours after his admission, he became quite agitated +screaming for lorazepam and hydromorphone. He receieved another +10 mg diazepam to treat DT's but remained agitated and continued +to yell and struggle against restraints for the next two hours. +Went on to receive an additonal 20 mg diazepam then 10 mg +ziprasidone and finally 5 mg haloperidol. After this last +intervention the patient was once again somnolent and had a +right sided femoral CVL placed. +. +On arrival to the floor the patient is sedated and unresponsive. +Of note, he has history of multiple previous admissions to [**Hospital1 18**] +to EtOH withdrawal and with various drug seeking behaviors. + + +Past Medical History: +Polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + + +Social History: +Homeless. Active alchohol and heroin abuse. Drinks 1 bottle of +listerine and vodka daily and reports daily blackouts. Last +episode of sobriety was in [**2171**] for 9 months. He reports that he +has difficulty with detox because he has OCD and a fear of +people which makes shelters difficult for him. He is a +non-smoker + + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +Vitals: T: 97.1, HR 86, BP: 117/68 HR: 132 RR: 10 O2Sat: 98% RA + +GEN: Slightly disheveled middle aged male asleep in bed +HEENT: PERRL, sclera anicteric, mucous membranes appear dry, +poor dentition +NECK: No JVD, lymphadenopathy, trachea midline +CV: RRR, no M/R/G; 2+ radial, DP, and PT pulses bilaterally +PULM: Lungs CTAB, no W/R/R +ABD: Soft, NT, ND, +BS, no HSM, no masses +EXT: No C/C/E, no palpable cords +NEURO: Sedated, responds to painful stimuli, unable to converse +or answer questions. +SKIN: No jaundice, cyanosis, or gross dermatitis. No ecchymoses. + + + +Pertinent Results: +[**2182-3-31**] CXR: Lungs are clear. Heart size normal. No pleural +abnormality or evidence of central adenopathy. Lateral aspect of +the right lower chest is excluded from the study. + +[**2182-3-31**] 04:15AM BLOOD WBC-4.0 RBC-3.59* Hgb-9.9* Hct-30.4* +MCV-85 MCH-27.6 MCHC-32.6 RDW-17.1* Plt Ct-223 +[**2182-3-30**] 10:30PM BLOOD WBC-3.4* RBC-3.67* Hgb-10.5* Hct-30.4* +MCV-83 MCH-28.4 MCHC-34.4 RDW-16.3* Plt Ct-249 +[**2182-3-30**] 10:30PM BLOOD Neuts-49.3* Lymphs-36.1 Monos-6.2 +Eos-8.1* Baso-0.4 +[**2182-3-31**] 11:02AM BLOOD PT-13.0 PTT-27.3 INR(PT)-1.1 +[**2182-3-31**] 04:15AM BLOOD Glucose-96 UreaN-9 Creat-0.8 Na-140 K-3.7 +Cl-104 HCO3-32 AnGap-8 +[**2182-3-30**] 10:30PM BLOOD Glucose-85 UreaN-9 Creat-0.8 Na-144 +K-3.1* Cl-106 HCO3-25 AnGap-16 +[**2182-3-31**] 04:15AM BLOOD ALT-165* AST-151* LD(LDH)-243 AlkPhos-68 +Amylase-68 TotBili-0.3 +[**2182-3-30**] 10:30PM BLOOD CK(CPK)-500* +[**2182-3-30**] 10:30PM BLOOD cTropnT-<0.01 +[**2182-3-31**] 04:15AM BLOOD Phos-4.1 Mg-1.7 Iron-13* +[**2182-3-31**] 04:15AM BLOOD calTIBC-338 Ferritn-53 TRF-260 +[**2182-3-30**] 10:30PM BLOOD ASA-NEG Ethanol-111* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +37yoM hx alcoholism, multiple admits for detox and hx of +DTs/withdrawal szs, presenting with intoxication and agitation, +admitted to MICU for ethanol withdrawal and monitoring. +. +# ETOH intoxication/AMS: 37 y.o male with history of +polysubstance abues and multiple previous admits for detox/drug +seeking behavior. He presented intoxicated and became very +agitated in the ED requiring multiple sedating medications. The +patient was given a total of 40mg of valium in the ED. In the +ICU, he was given an additionl 5mg valium for anxiety. He was +also given thiamine, folate, and a multivitamin. Social work +was also contact[**Name (NI) **]. + The patient was transferred to the medicine floor and on the +am of [**4-1**] definitely appeared to be in clinical ETOH withdrawal +(despite his well-documented history of faking ETOH withdrawal +symptoms for benzos). The patient was aggressivley treated with +200 mg of valium in 9 hours and then determined to no longer +have any clinical evidence of ETOH withdrawal (involuntary +tremors). + However, the patient became very agitated and anxious. The +patient was again evaluated by the medicine attending and +clearly deemed to not be in ETOH withdrawal anymore. His +agitation and anxiety was now behavioral. + The patient's femoral line was removed with plan to monitor +overnight and d/c in am after shower with taxi voucher. + The patient shortly thereafter eloped from the hospital. + I would highly advocate that when the patient returns to [**Hospital1 18**] +that he be section 25'd. + + + +Medications on Admission: +. + +Discharge Medications: +None, patient eloped + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH withdrawal + +Patient eloped + +Discharge Condition: +Pt eloped + +Discharge Instructions: +Patient eloped + +Followup Instructions: +Patient eloped. +Would recommend section 25 when he eventually returns +intoxicated to ED + + +",6,2182-03-30 22:36:00,2182-04-01 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +37yom hx alcoholism, multiple admits for detox and hx of +dts/withdrawal szs, presenting with intoxication and agitation, +admitted to micu for ethanol withdrawal and monitoring. +. +# etoh intoxication/ams: 37 y.o male with history of +polysubstance abues and multiple previous admits for detox/drug +seeking behavior. he presented intoxicated and became very +agitated in the ed requiring multiple sedating medications. the +patient was given a total of 40mg of valium in the ed. in the +icu, he was given an additionl 5mg valium for anxiety. he was +also given thiamine, folate, and a multivitamin. social work +was also contact[**name (ni) **]. + the patient was transferred to the medicine floor and on the +am of [**4-1**] definitely appeared to be in clinical etoh withdrawal +(despite his well-documented history of faking etoh withdrawal +symptoms for benzos). the patient was aggressivley treated with +200 mg of valium in 9 hours and then determined to no longer +have any clinical evidence of etoh withdrawal (involuntary +tremors). + however, the patient became very agitated and anxious. the +patient was again evaluated by the medicine attending and +clearly deemed to not be in etoh withdrawal anymore. his +agitation and anxiety was now behavioral. + the patients femoral line was removed with plan to monitor +overnight and d/c in am after shower with taxi voucher. + the patient shortly thereafter eloped from the hospital. + i would highly advocate that when the patient returns to [**hospital1 18**] +that he be section 25d. + + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Anemia, unspecified; Lack of housing; Dysthymic disorder; Obsessive-compulsive disorders]" +5060,174823.0,24307,2182-04-07,24301,153063.0,2181-10-24,Discharge summary,"Admission Date: [**2181-10-23**] Discharge Date: [**2181-10-24**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5893**] +Chief Complaint: +CC:[**CC Contact Info 61604**] +Major Surgical or Invasive Procedure: +none + +History of Present Illness: + +HPI: 37YO man with long hx of alcohol abuse, with frequent ED +visits/hospitalizations for same was brought to the ED today +after being found by EMS sleeping on street. He reports drinking +[**2-8**] pints of vodka daily. He eats very little. He also drinks +listerine each night. He reports frequent falls (recent scalp +lac w/ staples; abrasion over face). His ETOH level was 434 at +10:00 AM. He was given Ativan 2 mg at 6:30 in the ED for CIWA +=13; then given Ativan 2 mg at 6:30pm for CIWA = 23. He was +admitted to the floor for EtOH withdrawal. +. +On arrival to the floor, the patient was given Valium 10 mg PO +and 10 mg IV over 40 minutes without improvement in his CIWA. +He is transferred to the ICU for further management. +. +Of note, previous admission in [**Month (only) 205**] for ETOH withdrawal pt +required 20mg PO valium q15min, then left AMA. +. +Pt not cooperative for further ROS. +. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Currently reports drinking ""at least"" a lint of vodka each +morning and listerine each evening. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration +for possession, estranged from family, never married, no +children, homeless + +Family History: +Possible OCD in his father. + +Physical Exam: +Vitals: 99.3, 110/64, 115, 18, 99% RA +GEN: diaphoretic, sitting in bed, anxious +HEENT:hematoma on R occipital area where staples removed last +week. scabb on bridge of nose and R temple. PERRLA 5mm->2mm, +EOMI, throat non-erythematous, poor dentition, MMM +Lungs: clear +CV: tachy, rrr +Abd: + bs soft, limited exam, no focal tenderness +ext: + tremor, no c/c/e + + +Pertinent Results: +Labs: +. +143 /103 / 11 /140 Ca: 8.8 Mg: 2.1 P: 3.3 +-------------- +3.9 /31 / 0.8 + +. +4.7 / 13.0 / 315 N:35.4 L:50.6 M:4.4 E:7.8 Bas:1.8 + ------- + 39.6 +. +Serum EtOH 434, Serum Benzo Pos, +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Urine Benzos Pos +Urine Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Imaging: None + + +Brief Hospital Course: +In summary, Mr. [**Known lastname 24927**] is a 37 yo male with history of ETOH +abuse presents with acute ETOH intoxication. +. +ETOH abuse. Patient has a long history of alcohol abuse, with +innumerable ED visits and hospitalizations for same. Patient +was initially on diazepam CIWA scale. Within twelve hours of +admission, patient was requesting to leave AMA. He was +evaluated by psychiatry who felt he had competence to leave AMA. + He was not a candidate for section 35. Risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + +Medications on Admission: +None + +Discharge Medications: +None. Patient left AMA. + +Discharge Disposition: +Home + +Facility: +AMA + +Discharge Diagnosis: +Alcohol abuse. + +Discharge Condition: +AMA + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + +",165,2181-10-23 18:54:00,2181-10-24 15:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +in summary, mr. [**known lastname 24927**] is a 37 yo male with history of etoh +abuse presents with acute etoh intoxication. +. +etoh abuse. patient has a long history of alcohol abuse, with +innumerable ed visits and hospitalizations for same. patient +was initially on diazepam ciwa scale. within twelve hours of +admission, patient was requesting to leave ama. he was +evaluated by psychiatry who felt he had competence to leave ama. + he was not a candidate for section 35. risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing]" +5060,143525.0,24309,2182-10-08,24308,156497.0,2182-06-18,Discharge summary,"Admission Date: [**2182-6-13**] Discharge Date: [**2182-6-18**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 4365**] +Chief Complaint: +EtOH intoxication, hypertension. + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +Please see admission note for full details. Briefly, 37yoM w/ +h/o severe alcoholism with multiple admissions for withdrawal, +HBV, HCV, who was found passed out on [**6-14**] after drinking more +vodka that his usual amount. He also reported a recent h/o +fighting with a friend, resulting in R hand and substernal chest +pain. He was admitted to the MICU after being found to be in +acute withdrawal with HTN (SBP to 200s) and HR>100. + + +MICU Course: Mr. [**Known lastname 24927**] was started on folate, thiamine, MTV, +and valium prn for CIWA >10. He was found to have hypernatremia +and was treated with gentle IV hydration and drinking to thirst. +His musculoskeletal pain was managed with Percocet. Psychiatry +was consulted on day of admission to assess patient's capacity +to leave AMA. He initially agreed to voluntarily stay in the +hospital and completing a Section 35 on [**6-17**], as he did not meet +criteria for Section 12 for a psychiatric admission. He was +reported to manipulate nurses on floor asking for higher/more +frequent doses of Diazepam, with subjective complaints not +necessarily correlating to changes in vital signs. Patient was +reportedly [**Doctor Last Name **] high for tremor, anxiety, and reported +hallucinations with consistent stable vital signs. Psychiatry +recommended starting a standing Valium taper with CIWA for +objective signs of withdrawal only. + + +On arrival to the floor, the patient reported ""pain everywhere"", +and when elicited, focused on chest pain. He also reported +having ""withdrawal"", experiencing hot/cold flashes, skin +crawling, anxiety, and tremors. He wanted more pain medicine +(Percocet), and said that he would leave if he did not get +adequate pain medicine. + + +Past Medical History: +1. polysubstance abuse: ETOH, listerine, heroin, IVDU, +benzodiazepines +2. ethanol abuse, hx DTs and withdrawal seizures, intubated in +past +3. hepatitis C +4. hepatitis B +4. compartment syndrome RLE, [**2171**] +5. OCD and anxiety +6. depression with hx suicidal ideations and attempts +8. chronic bilateral hand swelling +9. severe peripheral neuropathy + +Social History: +He reports drinking [**2-8**] gallon vodka and listerine daily. +History of heroin, IVDU, benzodiazepine abuse, alcohol +withdrawal seizures and delerium tremens. +States he does not speak to any family members, never married, +no children. He is currently homeless and states he does not +like shelters because he gets ""nervous around all the people"". + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. +He reports his father had depression, alcoholism and +questionable OCD. + +Physical Exam: +VITALS: T: 97.7 BP 97/63 HR 68 RR 18 SpO2 97/RA +GENERAL: lying comfortably in bed, wearing cap, sheets pulled +tight over body, no obvious tremors +PSYCH: Combative +Pt refused all other components of PE + + +Pertinent Results: +Labs at Admission: +[**2182-6-13**] 06:50PM BLOOD WBC-4.4 RBC-4.61 Hgb-12.9* Hct-39.6* +MCV-86 MCH-27.9 MCHC-32.5 RDW-16.0* Plt Ct-158 +[**2182-6-13**] 06:50PM BLOOD Neuts-35.6* Lymphs-56.9* Monos-2.0 +Eos-4.7* Baso-0.8 +[**2182-6-13**] 06:50PM BLOOD Glucose-80 UreaN-8 Creat-0.8 Na-147* +K-4.2 Cl-109* HCO3-23 AnGap-19 +[**2182-6-14**] 07:09PM BLOOD ALT-55* AST-90* AlkPhos-98 TotBili-0.9 +[**2182-6-13**] 06:50PM BLOOD Calcium-8.6 Phos-4.0 Mg-1.9 +[**2182-6-13**] 06:50PM BLOOD ASA-NEG Ethanol-368* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Imaging Studies: + +Right hand plain film ([**6-14**]): +Abnormal curvilinear fragment identified just distal to the +first interphalangeal joint (volar aspect) as above. Please +correlate clinically, particularly on the volar aspect. This is +difficult to confirm given the lack of non- localizing symptoms. + +CXR ([**6-14**]): +Since [**2182-4-5**], lungs remain clear. The +cardiomediastinal silhouette and hilar contours are unchanged, +including minimal prominence of the ascending aorta, could be +related to systemic hypertension. There is no pleural effusion. + + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with a PMH s/f severe alcoholism with +several ICU admissions for management alchohol withdrawl in the +past, HCV, and HBV, admitted to the [**Hospital Unit Name 153**] for alcohol withdrawal. + +# Alcohol withdrawal: The patient was maintained on a CIWA scale +which required active intervention until the evening of [**6-16**]. +He was also continued on Folate, Thiamine and multivitamin. As +of the time of leaving the ICU, the patient had agreed to enter +Detox, but Psych/Social work had also started the Section 35 +process. The patient was called out to the floor after being +stable on decreasing doses of valium. He was started on a +standing valium taper when arriving on the floor. At time of +discharge, he had no signs of objective withdrawal. He was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# Hand pain: Questionable finger fracture on x-ray from recent +fighting. The patient was evaluated by hand and found to not +need operative intervention or splinting. Pain was controlled +with percocet while inpatient. + +# Hypernatremia: Attributed to dehydration from EtOH abuse. The +patient self corrected with PO intake and IV hydration. + +# Peripheral neuropathy: Attributed in the past to EtOH abuse. +Recent folate and B12 within normal limits. No hx of diabetes. +Pain was controlled with analgesics. + + +Medications on Admission: +(not taking any, but supposed to be on the following) +Prozac (pt thinks 40 mg daily) +Klonopin 1 mg TID +Trileptal (dose uncertain) +Remeron (dose uncertain) + +Discharge Medications: +1. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +2. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*0* +3. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +4. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +5. Oxcarbazepine 300 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +6. Gabapentin 100 mg Capsule Sig: Two (2) Capsule PO Q8H (every +8 hours). +Disp:*60 Capsule(s)* Refills:*0* +7. Prozac 40 mg Capsule Sig: One (1) Capsule PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses +Alcohol withdrawal +Right hand pain, no fracture + +Secondary Diagnoses +Anemia +Peripheral Neuropathy +Hepatitis B +Hepatitis C + + +Discharge Condition: +Patient afebrile with stable vital signs, discharged with plans +for alcohol detoxification program under section 35 + + +Discharge Instructions: +You have been admitted to the hospital for alcohol withdrawal. +You were discharged under section 35 with plans for +detoxification program. + +Please take all your medications as prescribed. The following +changes were made to your medication regimen. +1. Your klonopin was discontinued +2. Your remeron was discontinued +3. You were started on neurontin for pain +4. You were started on iron for your anemia +5. You were also started on thiamine, folate and multivitamins +for your nutritional health +Please keep all your follow up appointments as scheduled. + +Please seek medical attention or return to the emergency room if +you experience any fevers > 101 degrees, difficulty breathing, +chest pain, seizures, or any other concern symptoms. + +Followup Instructions: +Please make an appointment to see your primary care physician +[**Last Name (NamePattern4) **]. [**First Name (STitle) **]. He can be reached at [**Telephone/Fax (1) 61608**]. + + + +Completed by:[**2182-6-18**]",112,2182-06-14 20:51:00,2182-06-18 11:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with a pmh s/f severe alcoholism with +several icu admissions for management alchohol withdrawl in the +past, hcv, and hbv, admitted to the [**hospital unit name 153**] for alcohol withdrawal. + +# alcohol withdrawal: the patient was maintained on a ciwa scale +which required active intervention until the evening of [**6-16**]. +he was also continued on folate, thiamine and multivitamin. as +of the time of leaving the icu, the patient had agreed to enter +detox, but psych/social work had also started the section 35 +process. the patient was called out to the floor after being +stable on decreasing doses of valium. he was started on a +standing valium taper when arriving on the floor. at time of +discharge, he had no signs of objective withdrawal. he was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# hand pain: questionable finger fracture on x-ray from recent +fighting. the patient was evaluated by hand and found to not +need operative intervention or splinting. pain was controlled +with percocet while inpatient. + +# hypernatremia: attributed to dehydration from etoh abuse. the +patient self corrected with po intake and iv hydration. + +# peripheral neuropathy: attributed in the past to etoh abuse. +recent folate and b12 within normal limits. no hx of diabetes. +pain was controlled with analgesics. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Hyperosmolality and/or hypernatremia; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Unspecified essential hypertension; Anemia, unspecified; Pain in limb; Unarmed fight or brawl; Dysthymic disorder; Obsessive-compulsive disorders; Alcoholic polyneuropathy]" +5060,148207.0,24313,2183-02-03,24311,119255.0,2182-12-13,Discharge summary,"Admission Date: [**2182-12-10**] Discharge Date: [**2182-12-13**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 1936**] +Chief Complaint: +EtOH withdrawal, R hand swelling/erythema + +Major Surgical or Invasive Procedure: +[**12-11**]-R femoral central line + +History of Present Illness: +37 year-old homeless gentleman with a history of severe +alcoholism with multiple admission to [**Hospital1 18**] for management of +withdrawl, most recently d/c'ed [**2182-11-12**], also with hx of DTs, +seizure, HBV, HCV, who presented to [**Hospital1 18**] BIBEMS for +intoxication. The pt unfortunately does not recall any of the +events surrounding how he came to the ED. Pt also states his +hands and feet are numb. + +however he does remember drinking three pints of vodka with a +friend two days ago, which is more alcohol that he usually +drinks (typically one bottle of Listerine and one pint of vodka +daily). He denies doing this for any specific reason; he simply +wanted to forget about some of his problems. [**Name (NI) **] denies any SI or +HI. + +The pt does report recently engaging in a ""mock fighting"" event +with on of his friends. During this fight he delivered several +full-force blows with his right hand, and he has subsequently +developed right hand pain with swelling of the third, fourth and +fifth digits. Additionally, the pt was hit in the chest +full-force roughly twenty times, and now endorses a constant +substernal ache. + +In the ED, triage VS: 95.3 160 113/86 16 100%RA. Exam revealed +agitated male with swollen hands. EKG showed sinus tachycardia. +EtOH level 375. He was given 10mg po diazepam followed by IV +diazapam 10mg x 3. A TLC was placed for access. CXR was +negative. Hand Xray negative. He was then admitted to the [**Hospital Unit Name 153**] +for further care. Most recent VS: afebrile 100 117/64 18 98%. + +As above. No fevers or chills. The pt denies any change in +vision or difficulty swallowing. No nausea or vomiting. No +cough, SOB or wheeze. No abdominal pain. No dysuria or abnormal +bowel movements. + + +Past Medical History: +1. Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From Mass originally. Not in contact with any family members, +never married, no children. Homeless, lives at [**Location (un) 7073**] T +station. Panhandles for money; has SSI and rep-payee, [**Doctor First Name **] at +Community Action in Cities in [**Location (un) **] and she in turns sends him +a check for $125/week to [**Location (un) 33316**] House. Currently drinks one +fifth of listerine and [**2-8**] fifths rum daily. + +Substance use hx: Long and severe hx of alcohol with +self-reported withdrawal seizures and DTs; states that when he +can't use alcohol he will use other ""medications"" including BZPs +and narcotics. Multiple detoxes, multiple Section 35s. Also +history of opiates and IVDU. + + +Family History: +Father with depression, OCD and alcoholism. physically abused as +child Mother died of DM complications. + +Physical Exam: +Gen: Chronically ill appearing adult male, no acute distress. +HEENT: PERRL, EOMI. Dry MM. Conjunctiva well pigmented. +Neck: Supple, without adenopathy or JVD. No tenderness with +palpation. +Chest: Tender to palpation across anterior chest wall. CTAB +anterior and posterior. +Cor: Normal S1, S2. RRR, but mildly tachycardic with minimal +exertion. No murmurs appreciated. +Abdomen: Soft, non-tender and non-distended. +BS, no HSM. +Extremity: Pain, moderate swelling and erythema over 3rd, 4th +and 5th digits of right hand. Otherwise warm, without edema. 2+ +DP pulses bilat. +Neuro: Alert and oriented. CN 2-12 intact. Motor strength intact +in all extremities. Diminished peripheral sensation. Positive +intention tremor; gain assessment deferred + +Pertinent Results: +[**2182-12-10**] 10:02PM GLUCOSE-161* UREA N-17 CREAT-0.8 SODIUM-141 +POTASSIUM-3.4 CHLORIDE-103 TOTAL CO2-20* ANION GAP-21* +[**2182-12-10**] 10:02PM OSMOLAL-339* +[**2182-12-10**] 10:02PM ETHANOL-206* +[**2182-12-10**] 03:12PM GLUCOSE-143* UREA N-19 CREAT-1.0 SODIUM-143 +POTASSIUM-3.4 CHLORIDE-100 TOTAL CO2-22 ANION GAP-24* +[**2182-12-10**] 03:12PM ALT(SGPT)-114* AST(SGOT)-156* CK(CPK)-441* +ALK PHOS-87 TOT BILI-0.4 + +CXR [**2182-12-10**]: In comparison with study of [**10-5**], the heart +remains within normal limits and there is no evidence of +vascular congestion, pleural effusion, or acute pneumonia. + +HAND XRAY [**2182-12-10**]: There is equivocal soft tissue swelling in +relationship to the PIP joint of the fifth finger and I cannot +entirely exclude a subtle intra-articular fracture of the distal +portion of this proximal phalanx. Localizing history, which is +not available to me, would be helpful in this regard. Exam +otherwise normal with no overt fracture or joint space +narrowing. Other than the equivocal fifth finger findings there +is no change from similar exam [**2182-6-13**]. + + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37 year-old gentleman w/ a PMH s/f severe +alcoholism with several ICU admissions for management alchohol +withdrawl in the past, HCV, and HBV, admitted to the [**Hospital Unit Name 153**] for +alcohol withdrawal. +. +#. Alcohol withdrawal: He was treated in the [**Hospital Unit Name 153**] for alcohol +withdrawal. He received 40 mg of valium (10 mg po x 4) thus +receiving a total of 70 mg of valium over the course of 19 +hours. It was noted that if the patient was left alone his VS +were stable. With that objective evidence his valium was slowly +decreased to to 5 mg po q 6hours for 24 hours and then d/c'ed. +On [**2182-12-11**] he was also noted to have apneic episodes where he +would desat to the 80s and then his sats would improve with +stimulation. His last dose of valium was at 1200pm on [**2182-12-12**]. +He was then sent to the floor at 2100. He no longer showed any +signs of alcohol withdrawal for at least 24 hrs prior to +discharge. CIWA scale was discontinued. Given his numerous +admissions for substance abuse, the psychiatry team was +consulted and given his poor insight among other considerations, +deteriorating health in particular, felt that that he did not +have capacity to decide to leave AMA and a Section 35 was +completed. +. +# Hand pain: Questionable finger fracture on x-ray, although +this location does not correspond particularly well to pt's +symptoms. Treated with NSAIDs. +. +#. Peripheral neuropathy: Attributed in the past to EtOH abuse. +Recent folate and B12 within normal limits. No hx of diabetes. +Will control pain with analgesics for now; consider more +definitive therapy when acute issues resolved. Repleted B12, +folate, replete vitamins + + +Medications on Admission: +(not taking any, but supposed to be on the following) +Prozac (pt thinks 40 mg daily) +Trileptal (dose uncertain) +Remeron (dose uncertain) +Pt says he is on Klonopin but confirms with psych staff that he +is not and should not be on this med + +Discharge Medications: +1. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Ibuprofen 400 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours) as needed for pain. +3. Acetaminophen 650 mg Tablet Sig: One (1) Tablet PO Q6H (every +6 hours) as needed for pain. +4. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). + + +Discharge Disposition: +Extended Care + +Discharge Diagnosis: +Alcohol withdrawal +Substance abuse +Hand pain + + +Discharge Condition: +stable, no further alcohol withdrawal + + +Discharge Instructions: +You were admitted to the hospital for alcohol withdrawal and +were treated for this. You have not had any objective symptoms +of withdrawal for 24 hrs and not required medications prior to +discharge. You were to be treated at an inpatient facility for +substance abuse. + +If you have symptoms of chest pain, shortness of breath, +seizures, hallucinations or if your condition worsens in any way +seek immediate medical attention. + +Please take all medications as prescribed. + +Followup Instructions: +Follow-up with a primary care doctor at [**Telephone/Fax (1) 12802**] at +[**Hospital1 3278**]/[**Hospital1 336**] or per the recommendation of your inpatient facility + + + +",52,2182-12-10 16:45:00,2182-12-13 13:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,DISCH-TRAN TO PSYCH HOSP,ETOH WITHDRAWAL," +mr. [**known lastname 24927**] is a 37 year-old gentleman w/ a pmh s/f severe +alcoholism with several icu admissions for management alchohol +withdrawl in the past, hcv, and hbv, admitted to the [**hospital unit name 153**] for +alcohol withdrawal. +. +#. alcohol withdrawal: he was treated in the [**hospital unit name 153**] for alcohol +withdrawal. he received 40 mg of valium (10 mg po x 4) thus +receiving a total of 70 mg of valium over the course of 19 +hours. it was noted that if the patient was left alone his vs +were stable. with that objective evidence his valium was slowly +decreased to to 5 mg po q 6hours for 24 hours and then d/ced. +on [**2182-12-11**] he was also noted to have apneic episodes where he +would desat to the 80s and then his sats would improve with +stimulation. his last dose of valium was at 1200pm on [**2182-12-12**]. +he was then sent to the floor at 2100. he no longer showed any +signs of alcohol withdrawal for at least 24 hrs prior to +discharge. ciwa scale was discontinued. given his numerous +admissions for substance abuse, the psychiatry team was +consulted and given his poor insight among other considerations, +deteriorating health in particular, felt that that he did not +have capacity to decide to leave ama and a section 35 was +completed. +. +# hand pain: questionable finger fracture on x-ray, although +this location does not correspond particularly well to pts +symptoms. treated with nsaids. +. +#. peripheral neuropathy: attributed in the past to etoh abuse. +recent folate and b12 within normal limits. no hx of diabetes. +will control pain with analgesics for now; consider more +definitive therapy when acute issues resolved. repleted b12, +folate, replete vitamins + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Acidosis; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; ; Hypovolemia; Closed fracture of middle or proximal phalanx or phalanges of hand; Unarmed fight or brawl; Sedative, hypnotic or anxiolytic dependence, continuous; Alcoholic polyneuropathy; Chronic hepatitis C without mention of hepatic coma; Dysthymic disorder; Lack of housing; Obsessive-compulsive disorders]" +5060,148207.0,24313,2183-02-03,24310,193317.0,2182-10-11,Discharge summary,"Admission Date: [**2182-10-10**] Discharge Date: [**2182-10-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +alcoholic intoxication and heroin abuse + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Mr. [**Known lastname 24927**] is a 38 yo M with PMH of polysubstance abuse who +presents with acute alcoholic intoxication and heroin abuse. He +was found around [**Location (un) **] station and brought to [**Hospital1 18**]. On +arrival to [**Hospital1 18**], he reported also snorting heroin. +In the ED, VS: T 99 BP 98/73 HR 102 RR17 99%RA. He was initially +alert and awake, then became somnolent with RR of 6 and O2 sat +of 70%. He received naloxone with immediate awakening. RR +normalized and O2sat was normal. After several hours in [**Name (NI) **], pt +became increasingly agitated and received multiple doses of +valium for elevated CIWA scale, receiving total of 50mg PO. +Pt has frequent visits to [**Hospital1 18**]. Was recently admitted to MICU +Green on [**2182-10-5**]. At that time, seen by psychiatry who left +recommendation regarding administration of benzos as patient +frequently is administered high doses of benzodiazepines for +drug seeking behavior. + + +Past Medical History: +Per Discharge Summary ([**2182-6-18**]) +Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From previous DC summary. States he does not speak to any family +members, never married, no children. Homeless, states he does +not like shelters because he gets ""nervous around all the +people."" + +Family History: +Father with depression, OCD and alcoholism. Mother died of DM +complications + +Physical Exam: +VS: T 96 HR 86 BP 128/79 02sat 97% RR 12 +GEN: Disheveled, appears older than stated age +HEENT: EOMI, PERRL +NECK: Supple +CHEST: CTABL +CV: RRR, S1S2, no m/r/g +ABD:Soft, NT, ND +EXT: No c/c/e +Skin: Pruritic papular rash on trunk, groin, ankles bilaterally + +NEURO: speech slurred, unsteady gait, CN ii-xii intact; able to +answer questions appropriately +. + + +Pertinent Results: +[**2182-10-10**] 03:10PM GLUCOSE-83 UREA N-12 CREAT-0.8 SODIUM-143 +POTASSIUM-3.9 CHLORIDE-105 TOTAL CO2-26 ANION GAP-16 +[**2182-10-10**] 03:10PM estGFR-Using this +[**2182-10-10**] 03:10PM CALCIUM-9.0 PHOSPHATE-3.1 MAGNESIUM-1.8 +[**2182-10-10**] 03:10PM ASA-NEG ETHANOL-244* ACETMNPHN-NEG +bnzodzpn-POS barbitrt-NEG tricyclic-NEG +[**2182-10-10**] 03:10PM WBC-5.1# RBC-4.36* HGB-12.5* HCT-37.7* MCV-87 +MCH-28.6 MCHC-33.0 RDW-16.5* +[**2182-10-10**] 03:10PM NEUTS-33.2* BANDS-0 LYMPHS-58.8* MONOS-5.5 +EOS-1.6 BASOS-0.9 +[**2182-10-10**] 03:10PM HYPOCHROM-NORMAL ANISOCYT-NORMAL +POIKILOCY-NORMAL MACROCYT-NORMAL MICROCYT-NORMAL +POLYCHROM-NORMAL +[**2182-10-10**] 03:10PM PLT COUNT-239 + +Brief Hospital Course: +A/P: 38 yo M with PMH of ETOH abuse/withdrawal and multiple +hospitalizations presented with acute intoxication and heroin +use requiring naloxone in ED. +. +ETOH intoxication: ETOH level 244. Speech somewhat slurred on +exam. Pt admits to drinking rum and Listerine. Received Valium +50mg total in ED for CIWA >10. Had 5mg x 3 of Valium in the +MICU. Given thiamine, folate, MVI. Social work was contact[**Name (NI) **] and +paperwork for a section 35 was started. Pt left AMA before +paperwork could be completed (will take several days). Will need +to continue paperwork if pt returns in near future. + +Scabies: Pt was treated with permethrin cream and Ivermectin x +1. + +Pt left AMA before further care was done for pt. + + +Medications on Admission: +Per Discharge Summary ([**2182-6-18**]), Unknown Compliance +1. Folic Acid 1mg Daily +2. Thiamine 100mg Daily +3. MVT One tab Daily +4. Ferrous Sulfate 325mg One Tab Daily +5. Oxcarbazepine 300mg one tablet [**Hospital1 **] +6. Gabapentin 200mg PO Q8H +7. Prozac 40mg Once Daily + + +Discharge Medications: +left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +left AMA + +Discharge Condition: +left AMA + +Discharge Instructions: +left AMA + +Followup Instructions: +left AMA + + +Completed by:[**2182-10-11**]",115,2182-10-10 18:16:00,2182-10-11 13:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +a/p: 38 yo m with pmh of etoh abuse/withdrawal and multiple +hospitalizations presented with acute intoxication and heroin +use requiring naloxone in ed. +. +etoh intoxication: etoh level 244. speech somewhat slurred on +exam. pt admits to drinking rum and listerine. received valium +50mg total in ed for ciwa >10. had 5mg x 3 of valium in the +micu. given thiamine, folate, mvi. social work was contact[**name (ni) **] and +paperwork for a section 35 was started. pt left ama before +paperwork could be completed (will take several days). will need +to continue paperwork if pt returns in near future. + +scabies: pt was treated with permethrin cream and ivermectin x +1. + +pt left ama before further care was done for pt. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Opioid abuse, unspecified; Chronic hepatitis C without mention of hepatic coma; Obsessive-compulsive disorders; Anxiety state, unspecified; Cerebral degeneration, unspecified; Lack of housing; Scabies; Alcoholic polyneuropathy]" +5060,119255.0,24311,2182-12-13,24309,143525.0,2182-10-08,Discharge summary,"Admission Date: [**2182-10-7**] Discharge Date: [**2182-10-8**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 338**] +Chief Complaint: +EtOH Intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Pt is a 38 yo male with a PMH significant for Etoh and Poly +substance abuse, Hep B, and Hep C. Pt was found down on the +street stating that he wanted to be run over by a car. Pt +recently was admitted to the MICU with EtOH intoxication +yesterday, pt left AMA. +In ED patient vitals were BP 93/58 - 156/89, HR 70-80s, T 98, +100% on 2L. Initially given 5mg haldol for agitation/combative +behavior, later given 10mg Valium PO. No access attained. +Complained of some tail bone pain which was worked up with plain +film of coccyx. ED was prepared for DC however pt reported +difficulty walking. + +Patient appears intoxicated and is not willing to answer +questions. Pt does not some abdomen, back, and extremity pain +globally. + +Past Medical History: +Per Discharge Summary ([**2182-6-18**]) +Poly Substance Abuse: Benzo/Opiates/IVDU +2. Ethanol Abuse: hx of DTs and withdrawal seizures, intubated +in the past. +3. Hepatitis C +4. Hepatitis B +5. Compartment Syndrom RLE, [**2171**] +6. OCD and Anxiety +7. Depression with hx of suicidal ideations +8. Sever Peripheral Neuropathy + + +Social History: +From previous DC summary. States he does not speak to any family +members, never married, no children. Homeless, states he does +not like shelters because he gets ""nervous around all the +people."" + +Family History: +Father with depression, OCD and alcoholism. Mother died of DM +complications + +Physical Exam: +T BP 121 HR 76 RR 20 O2sat 100% on RA +General - Resting comfortably in bed, no acute distress, Appears +intoxicated and is not interested in answering questions. +HEENT - Sclera anicteric, Lips dry +Neck - Supple, JVP not elevated, no LAD +Pulm - CTA bilaterally; no wheezes, rales, or rhonchi +CV - RRR, normal S1/S2; no murmurs, rubs, or gallops +Abdomen - Soft, Mild tenderness on palpation of abdomen +Ext - Warm, well perfused, radial and DP pulses 2+; no clubbing, +cyanosis or edema. Pain with palpation of lower extremity. +Neuro - Pt is not willing to participate with exam. Still +appears somewhat intoxicate, however mental status is improving. +Able to move all extremities. PERRL. EOMI. + + +Pertinent Results: +Radiograph Coccyx: Normal bony mineralization and alignment. No +evidence of fracture. Apparent mild sclerosis overlying the +right S1, S2 region is not appreciated on the more tilted views +and is likely artifactual. No evidence of fracture. Views of the +L5-S1 region do show some evidence of degenerative osteophyte +formation of the anterosuperior aspect of L5, probably some +posterior osteophytes of the L5-S1 disc interspace. + +Brief Hospital Course: +Pt is a 38 year old male with significant hx of +EtOH/Polysubstance abuse, who presented today with EtOH +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# Airway obstruction: Required a Code Blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. It resolved without intubation. Sats remained +normal. +. +#.EtOH Intoxication/Withdrawal: Received multiple doses of +ativan and valium. No objective signs of withdrawal by time of +his transfer to the MICU. Was also given MV and thiamine and +folate. +. +#. Scabies: Found to have extensive infection. Was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.Hep B/Hep C: Hep B infection cleared based on most recent +serologies. AST>ALT on recent liver function tests, most likely +was secondary to EtOH abuse. +. + +#. Code status: DNR/DNI confirmed 2 days prior with psych +. +Pt leave AMA on the morning of [**2182-10-8**]. + +Medications on Admission: +Per Discharge Summary ([**2182-6-18**]), Unknown Compliance +1. Folic Acid 1mg Daily +2. Thiamine 100mg Daily +3. MVT One tab Daily +4. Ferrous Sulfate 325mg One Tab Daily +5. Oxcarbazepine 300mg one tablet [**Hospital1 **] +6. Gabapentin 200mg PO Q8H +7. Prozac 40mg Once Daily + + +Discharge Medications: +left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Left AMA + + +Discharge Condition: +Left AMA + + +Discharge Instructions: +Left AMA + +Followup Instructions: +Left AMA + + + +Completed by:[**2182-10-9**]",66,2182-10-07 02:09:00,2182-10-08 09:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +pt is a 38 year old male with significant hx of +etoh/polysubstance abuse, who presented today with etoh +intoxication and developed respiratory distress, felt to be self +induced airway obstruction. +. +# airway obstruction: required a code blue, and at first there +was concern about a allergic response, later thought to be +psychogenic. it resolved without intubation. sats remained +normal. +. +#.etoh intoxication/withdrawal: received multiple doses of +ativan and valium. no objective signs of withdrawal by time of +his transfer to the micu. was also given mv and thiamine and +folate. +. +#. scabies: found to have extensive infection. was treated with +5% permethrin cream x 1, but will need repeat out pt treatment +in one week. +. +#.hep b/hep c: hep b infection cleared based on most recent +serologies. ast>alt on recent liver function tests, most likely +was secondary to etoh abuse. +. + +#. code status: dnr/dni confirmed 2 days prior with psych +. +pt leave ama on the morning of [**2182-10-8**]. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Suicidal ideation; Scabies; Other respiratory abnormalities; Obsessive-compulsive personality disorder; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing; Dysthymic disorder]" +5060,119255.0,24311,2182-12-13,24308,156497.0,2182-06-18,Discharge summary,"Admission Date: [**2182-6-13**] Discharge Date: [**2182-6-18**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 4365**] +Chief Complaint: +EtOH intoxication, hypertension. + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +Please see admission note for full details. Briefly, 37yoM w/ +h/o severe alcoholism with multiple admissions for withdrawal, +HBV, HCV, who was found passed out on [**6-14**] after drinking more +vodka that his usual amount. He also reported a recent h/o +fighting with a friend, resulting in R hand and substernal chest +pain. He was admitted to the MICU after being found to be in +acute withdrawal with HTN (SBP to 200s) and HR>100. + + +MICU Course: Mr. [**Known lastname 24927**] was started on folate, thiamine, MTV, +and valium prn for CIWA >10. He was found to have hypernatremia +and was treated with gentle IV hydration and drinking to thirst. +His musculoskeletal pain was managed with Percocet. Psychiatry +was consulted on day of admission to assess patient's capacity +to leave AMA. He initially agreed to voluntarily stay in the +hospital and completing a Section 35 on [**6-17**], as he did not meet +criteria for Section 12 for a psychiatric admission. He was +reported to manipulate nurses on floor asking for higher/more +frequent doses of Diazepam, with subjective complaints not +necessarily correlating to changes in vital signs. Patient was +reportedly [**Doctor Last Name **] high for tremor, anxiety, and reported +hallucinations with consistent stable vital signs. Psychiatry +recommended starting a standing Valium taper with CIWA for +objective signs of withdrawal only. + + +On arrival to the floor, the patient reported ""pain everywhere"", +and when elicited, focused on chest pain. He also reported +having ""withdrawal"", experiencing hot/cold flashes, skin +crawling, anxiety, and tremors. He wanted more pain medicine +(Percocet), and said that he would leave if he did not get +adequate pain medicine. + + +Past Medical History: +1. polysubstance abuse: ETOH, listerine, heroin, IVDU, +benzodiazepines +2. ethanol abuse, hx DTs and withdrawal seizures, intubated in +past +3. hepatitis C +4. hepatitis B +4. compartment syndrome RLE, [**2171**] +5. OCD and anxiety +6. depression with hx suicidal ideations and attempts +8. chronic bilateral hand swelling +9. severe peripheral neuropathy + +Social History: +He reports drinking [**2-8**] gallon vodka and listerine daily. +History of heroin, IVDU, benzodiazepine abuse, alcohol +withdrawal seizures and delerium tremens. +States he does not speak to any family members, never married, +no children. He is currently homeless and states he does not +like shelters because he gets ""nervous around all the people"". + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. +He reports his father had depression, alcoholism and +questionable OCD. + +Physical Exam: +VITALS: T: 97.7 BP 97/63 HR 68 RR 18 SpO2 97/RA +GENERAL: lying comfortably in bed, wearing cap, sheets pulled +tight over body, no obvious tremors +PSYCH: Combative +Pt refused all other components of PE + + +Pertinent Results: +Labs at Admission: +[**2182-6-13**] 06:50PM BLOOD WBC-4.4 RBC-4.61 Hgb-12.9* Hct-39.6* +MCV-86 MCH-27.9 MCHC-32.5 RDW-16.0* Plt Ct-158 +[**2182-6-13**] 06:50PM BLOOD Neuts-35.6* Lymphs-56.9* Monos-2.0 +Eos-4.7* Baso-0.8 +[**2182-6-13**] 06:50PM BLOOD Glucose-80 UreaN-8 Creat-0.8 Na-147* +K-4.2 Cl-109* HCO3-23 AnGap-19 +[**2182-6-14**] 07:09PM BLOOD ALT-55* AST-90* AlkPhos-98 TotBili-0.9 +[**2182-6-13**] 06:50PM BLOOD Calcium-8.6 Phos-4.0 Mg-1.9 +[**2182-6-13**] 06:50PM BLOOD ASA-NEG Ethanol-368* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Imaging Studies: + +Right hand plain film ([**6-14**]): +Abnormal curvilinear fragment identified just distal to the +first interphalangeal joint (volar aspect) as above. Please +correlate clinically, particularly on the volar aspect. This is +difficult to confirm given the lack of non- localizing symptoms. + +CXR ([**6-14**]): +Since [**2182-4-5**], lungs remain clear. The +cardiomediastinal silhouette and hilar contours are unchanged, +including minimal prominence of the ascending aorta, could be +related to systemic hypertension. There is no pleural effusion. + + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with a PMH s/f severe alcoholism with +several ICU admissions for management alchohol withdrawl in the +past, HCV, and HBV, admitted to the [**Hospital Unit Name 153**] for alcohol withdrawal. + +# Alcohol withdrawal: The patient was maintained on a CIWA scale +which required active intervention until the evening of [**6-16**]. +He was also continued on Folate, Thiamine and multivitamin. As +of the time of leaving the ICU, the patient had agreed to enter +Detox, but Psych/Social work had also started the Section 35 +process. The patient was called out to the floor after being +stable on decreasing doses of valium. He was started on a +standing valium taper when arriving on the floor. At time of +discharge, he had no signs of objective withdrawal. He was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# Hand pain: Questionable finger fracture on x-ray from recent +fighting. The patient was evaluated by hand and found to not +need operative intervention or splinting. Pain was controlled +with percocet while inpatient. + +# Hypernatremia: Attributed to dehydration from EtOH abuse. The +patient self corrected with PO intake and IV hydration. + +# Peripheral neuropathy: Attributed in the past to EtOH abuse. +Recent folate and B12 within normal limits. No hx of diabetes. +Pain was controlled with analgesics. + + +Medications on Admission: +(not taking any, but supposed to be on the following) +Prozac (pt thinks 40 mg daily) +Klonopin 1 mg TID +Trileptal (dose uncertain) +Remeron (dose uncertain) + +Discharge Medications: +1. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +2. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*0* +3. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +4. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*0* +5. Oxcarbazepine 300 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +6. Gabapentin 100 mg Capsule Sig: Two (2) Capsule PO Q8H (every +8 hours). +Disp:*60 Capsule(s)* Refills:*0* +7. Prozac 40 mg Capsule Sig: One (1) Capsule PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses +Alcohol withdrawal +Right hand pain, no fracture + +Secondary Diagnoses +Anemia +Peripheral Neuropathy +Hepatitis B +Hepatitis C + + +Discharge Condition: +Patient afebrile with stable vital signs, discharged with plans +for alcohol detoxification program under section 35 + + +Discharge Instructions: +You have been admitted to the hospital for alcohol withdrawal. +You were discharged under section 35 with plans for +detoxification program. + +Please take all your medications as prescribed. The following +changes were made to your medication regimen. +1. Your klonopin was discontinued +2. Your remeron was discontinued +3. You were started on neurontin for pain +4. You were started on iron for your anemia +5. You were also started on thiamine, folate and multivitamins +for your nutritional health +Please keep all your follow up appointments as scheduled. + +Please seek medical attention or return to the emergency room if +you experience any fevers > 101 degrees, difficulty breathing, +chest pain, seizures, or any other concern symptoms. + +Followup Instructions: +Please make an appointment to see your primary care physician +[**Last Name (NamePattern4) **]. [**First Name (STitle) **]. He can be reached at [**Telephone/Fax (1) 61608**]. + + + +Completed by:[**2182-6-18**]",178,2182-06-14 20:51:00,2182-06-18 11:05:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with a pmh s/f severe alcoholism with +several icu admissions for management alchohol withdrawl in the +past, hcv, and hbv, admitted to the [**hospital unit name 153**] for alcohol withdrawal. + +# alcohol withdrawal: the patient was maintained on a ciwa scale +which required active intervention until the evening of [**6-16**]. +he was also continued on folate, thiamine and multivitamin. as +of the time of leaving the icu, the patient had agreed to enter +detox, but psych/social work had also started the section 35 +process. the patient was called out to the floor after being +stable on decreasing doses of valium. he was started on a +standing valium taper when arriving on the floor. at time of +discharge, he had no signs of objective withdrawal. he was +discharged in the company of police to court for section 35 with +the collaboration of psych/social work. + +# hand pain: questionable finger fracture on x-ray from recent +fighting. the patient was evaluated by hand and found to not +need operative intervention or splinting. pain was controlled +with percocet while inpatient. + +# hypernatremia: attributed to dehydration from etoh abuse. the +patient self corrected with po intake and iv hydration. + +# peripheral neuropathy: attributed in the past to etoh abuse. +recent folate and b12 within normal limits. no hx of diabetes. +pain was controlled with analgesics. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Hyperosmolality and/or hypernatremia; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Unspecified essential hypertension; Anemia, unspecified; Pain in limb; Unarmed fight or brawl; Dysthymic disorder; Obsessive-compulsive disorders; Alcoholic polyneuropathy]" +5060,135773.0,24304,2181-12-14,24300,194191.0,2181-08-21,Discharge summary,"Admission Date: [**2181-8-20**] Discharge Date: [**2181-8-21**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2485**] +Chief Complaint: +etoh w/d + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +36 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions returns with alcohol intoxication. He +reports that he has been drinking daily since being released +from prison on [**7-10**]. He drinks enough vodka or listerine so +that he blacks out daily. He believes he was brought in by EMS +or a local after he was found intoxicated. Per ED reports, he +was BIBA after being found down. + +He was most recently admitted for EtOh withdrawal from [**2-24**] - +[**3-5**] and left AMA after his valium dose was tapered. He returned +on [**7-4**] with a fall but was discharged from the ED after a +negative head CT. +. +ED: VS on arrival 98.5 114 128/62 16 97% RA. Tox was negative +for cocaine, amphetamines. Serum tox was positive for etoh 448 +and benzos. Had anion gap of 18 but VBG of 7.49/33/58 and +lactate of 3.1. We was given 60-70 IV valium for withdrawal sx +of agitation, hypertension, and tachycardia. Also received 3L +IVF. +. +Currently, the patient reports having chest pain x1wk. he +thinks he was punched in the chest and has since had +intermittently dull/sharp nonradiating substernal chest pain. +Now it is [**9-16**] and sharp. It is not exertional nor assoc with +SOB or diaphoresis/n/v. Worse w palpation. Also reports +falling and hitting right forehead 10d ago. Has had no fevers +or residual HA since that time. +. +ROS otherwise pos for URI-like sx. no diarrhea. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures - once sent under +section 35 to prison due to concern that he was a severe threat +to himself with his drinking. required intubation in the past. +- has been seen recently by psychiatry in the past to evaluate +for possible section 35. + +Social History: +Drinks regularly, prefers listerine and vodka. Has been +drinking heavily since release from prison on [**8-9**]. +Homeless, lives on streets. Denies IVDU for >10yrs. Denies +cigs for>10 yrs. Denies SI or HI + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 99.8 110 96% RA RR12 133/111 +gen: agitated but redirectable. +Neuro: aao to person, place, time, situation. +- cn ii-xii intact +- motor [**6-11**] bilat upper/lower +- slightly tremulous upper ex +- [**Last Name (un) 36**] to light touch +- gait wide based and unsteady +- f-n intact bilat +- h-s impaired bilat +heent: old scar on right forehead. mm dry, jvp flat +cards: tachy, reg, no murmurs +resp: ctab +abd: BS+ NT ND soft, no rebound, no stigmata of liver dz +Ext: no edema. good pulses + +Pertinent Results: +EKG: Sinus tachy, nl axis, nl intervals, no acute st-t changes. +. +Labs: +VBG: 7.49/33/58 +Lactate 3.1 +. +142 102 10 +----------------< 87 +4.1 22 0.9 +Ca: 9.4 Mg: 2.0 P: 2.9 +Serum EtOH 448 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +. +WBC: 9.5 +HCT: 35.7 - at baseline +PLT: 208 +N:64.2 L:30.8 M:3.5 E:1.1 Bas:0.5 +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Repeat chemistry: +140 108 8 +-------------< 73 +3.3 20 0.7 +Ca: 8.0 Mg: 1.6 P: 1.9 +repeat lactate 3.1 + +Brief Hospital Course: +36M with ETOH dependence and frequent admissions for EtOH +intoxication presents with EtOH withdrawal. ICU-east course by +problem: +. +# Alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. Has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of DTs and w/d seizures, we treated +aggressively with valium in ICU. He received either 60-70 IV +valium in the ED. On arrival to the ICU, he was written for +valium 20mg PO q15m prn CIWA>10 and he received it almost as +frequently as written. He became less agitated after approx +80-100mg (in addition to the IV given in the ED) and then the +CIWA scale was spread out to 20mg PO prn q1h. He tolerated +this transition well. +- He received multivit, folate, thiamine in IVF then PO +- social work was consulted the morning after admission when +patient was demanding to leave. He felt he had enough valium +and actually refused another dose. We explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. He expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. He signed out +AMA with plans to seek outpatient treatment. +. +# Psych: No SI. We had plans to contact psychiatry morning +after admission particularly given his high valium need. +However, he expressed interest in leaving and we felt he had +capacity to make this decision. Social wk was involved but +psychiatry was not consulted. +. +# chest pain: EKG without ischemic changes. CP was reproducible +on palpation. Suspected MSK pain. He received one dose of +morphine for cp. We then treated with toradol, motrin, and +tylenol. We would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. His pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. Lactic acidosis not likely +given the alkalosis seen on VBG. Consider dehydration vs poor +quality sample. Infection less likely given no fever or +hypotension or any localizing signs of infection. Repeat +lactate remained 3.1. Etiology unclear and workup hindered by +patient leaving AMA. +. +# Anion gap: AG 18 in the ED with a normal HCO3 and alkalosis on +VBG. ASA negative as were other toxins. Difficult to interpret +but wonder if slightly increased AG is from the elevated +lactate. Repeat chemistries showed normal anion gap. +. +#Anemia - normocytic anemia, Hct at baseline +. +# PPx: Heparin sc tid, PPI given etoh abuse, bowel reg +. +# FEN: Regular diet, replete lytes prn, banana bag then IVF +. +# Access: PIV x1 +. +# Code: FULL +. +# Communication: Patient +. +# Dispo: Patient left AMA. + + +Medications on Admission: +none + +Discharge Medications: +none + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH Intoxication/Withdrawal + + +Discharge Condition: +fair + + +Discharge Instructions: +You were admitted to the hospital because you were found +intoxicated by EMS. You were admitted to the ICU and treated +with Valium for withdrawal. You were advised to stay in the +hospital for continued care and treatment of withdrawal however +you decided against medical advice that you no longer wished to +receive care. You spoke with the social worker before you left +the hospital and were advised to return to [**Street Address(1) 5904**] Inn +to speak with your outreach worker there. + +You signed out against medical advise. + +Followup Instructions: +Please speak with the Outreach worker [**Street Address(1) 29735**] Inn. + +Please return to the hospital should you have any concerning +symptoms including difficulty breathing, falls or injuries +requiring medical attention, concerning withdrawal symptoms. + + + +",115,2181-08-20 20:26:00,2181-08-21 11:10:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +36m with etoh dependence and frequent admissions for etoh +intoxication presents with etoh withdrawal. icu-east course by +problem: +. +# alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of dts and w/d seizures, we treated +aggressively with valium in icu. he received either 60-70 iv +valium in the ed. on arrival to the icu, he was written for +valium 20mg po q15m prn ciwa>10 and he received it almost as +frequently as written. he became less agitated after approx +80-100mg (in addition to the iv given in the ed) and then the +ciwa scale was spread out to 20mg po prn q1h. he tolerated +this transition well. +- he received multivit, folate, thiamine in ivf then po +- social work was consulted the morning after admission when +patient was demanding to leave. he felt he had enough valium +and actually refused another dose. we explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. he expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. he signed out +ama with plans to seek outpatient treatment. +. +# psych: no si. we had plans to contact psychiatry morning +after admission particularly given his high valium need. +however, he expressed interest in leaving and we felt he had +capacity to make this decision. social wk was involved but +psychiatry was not consulted. +. +# chest pain: ekg without ischemic changes. cp was reproducible +on palpation. suspected msk pain. he received one dose of +morphine for cp. we then treated with toradol, motrin, and +tylenol. we would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. his pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. lactic acidosis not likely +given the alkalosis seen on vbg. consider dehydration vs poor +quality sample. infection less likely given no fever or +hypotension or any localizing signs of infection. repeat +lactate remained 3.1. etiology unclear and workup hindered by +patient leaving ama. +. +# anion gap: ag 18 in the ed with a normal hco3 and alkalosis on +vbg. asa negative as were other toxins. difficult to interpret +but wonder if slightly increased ag is from the elevated +lactate. repeat chemistries showed normal anion gap. +. +#anemia - normocytic anemia, hct at baseline +. +# ppx: heparin sc tid, ppi given etoh abuse, bowel reg +. +# fen: regular diet, replete lytes prn, banana bag then ivf +. +# access: piv x1 +. +# code: full +. +# communication: patient +. +# dispo: patient left ama. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Alkalosis; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Acidosis; Chronic hepatitis C without mention of hepatic coma; Cocaine abuse, unspecified; Lack of housing; Anemia, unspecified; Other chest pain]" +5060,135773.0,24304,2181-12-14,24301,153063.0,2181-10-24,Discharge summary,"Admission Date: [**2181-10-23**] Discharge Date: [**2181-10-24**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5893**] +Chief Complaint: +CC:[**CC Contact Info 61604**] +Major Surgical or Invasive Procedure: +none + +History of Present Illness: + +HPI: 37YO man with long hx of alcohol abuse, with frequent ED +visits/hospitalizations for same was brought to the ED today +after being found by EMS sleeping on street. He reports drinking +[**2-8**] pints of vodka daily. He eats very little. He also drinks +listerine each night. He reports frequent falls (recent scalp +lac w/ staples; abrasion over face). His ETOH level was 434 at +10:00 AM. He was given Ativan 2 mg at 6:30 in the ED for CIWA +=13; then given Ativan 2 mg at 6:30pm for CIWA = 23. He was +admitted to the floor for EtOH withdrawal. +. +On arrival to the floor, the patient was given Valium 10 mg PO +and 10 mg IV over 40 minutes without improvement in his CIWA. +He is transferred to the ICU for further management. +. +Of note, previous admission in [**Month (only) 205**] for ETOH withdrawal pt +required 20mg PO valium q15min, then left AMA. +. +Pt not cooperative for further ROS. +. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Currently reports drinking ""at least"" a lint of vodka each +morning and listerine each evening. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration +for possession, estranged from family, never married, no +children, homeless + +Family History: +Possible OCD in his father. + +Physical Exam: +Vitals: 99.3, 110/64, 115, 18, 99% RA +GEN: diaphoretic, sitting in bed, anxious +HEENT:hematoma on R occipital area where staples removed last +week. scabb on bridge of nose and R temple. PERRLA 5mm->2mm, +EOMI, throat non-erythematous, poor dentition, MMM +Lungs: clear +CV: tachy, rrr +Abd: + bs soft, limited exam, no focal tenderness +ext: + tremor, no c/c/e + + +Pertinent Results: +Labs: +. +143 /103 / 11 /140 Ca: 8.8 Mg: 2.1 P: 3.3 +-------------- +3.9 /31 / 0.8 + +. +4.7 / 13.0 / 315 N:35.4 L:50.6 M:4.4 E:7.8 Bas:1.8 + ------- + 39.6 +. +Serum EtOH 434, Serum Benzo Pos, +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Urine Benzos Pos +Urine Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Imaging: None + + +Brief Hospital Course: +In summary, Mr. [**Known lastname 24927**] is a 37 yo male with history of ETOH +abuse presents with acute ETOH intoxication. +. +ETOH abuse. Patient has a long history of alcohol abuse, with +innumerable ED visits and hospitalizations for same. Patient +was initially on diazepam CIWA scale. Within twelve hours of +admission, patient was requesting to leave AMA. He was +evaluated by psychiatry who felt he had competence to leave AMA. + He was not a candidate for section 35. Risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + +Medications on Admission: +None + +Discharge Medications: +None. Patient left AMA. + +Discharge Disposition: +Home + +Facility: +AMA + +Discharge Diagnosis: +Alcohol abuse. + +Discharge Condition: +AMA + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + +",51,2181-10-23 18:54:00,2181-10-24 15:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +in summary, mr. [**known lastname 24927**] is a 37 yo male with history of etoh +abuse presents with acute etoh intoxication. +. +etoh abuse. patient has a long history of alcohol abuse, with +innumerable ed visits and hospitalizations for same. patient +was initially on diazepam ciwa scale. within twelve hours of +admission, patient was requesting to leave ama. he was +evaluated by psychiatry who felt he had competence to leave ama. + he was not a candidate for section 35. risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing]" +5060,135773.0,24304,2181-12-14,24302,184857.0,2181-11-20,Discharge summary,"Admission Date: [**2181-11-18**] Discharge Date: [**2181-11-20**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +ETOH Withdrawal + +Major Surgical or Invasive Procedure: +PICC placement ([**2181-11-19**]) + +History of Present Illness: +37 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions and ED evals returns with alcohol +intoxication and withdrawal. Presented to ED s/p unwitnessed +fall while intoxicated. Came in c/o L elbow and R hand pain. +Also with left supraorbital laceration that was repaired in the +ED. He reports currently drinking 1 bottle of Vodka and large +bottle of mouthwash daily. He has a hx of withdrawal seizures as +well as Section 35/Section 12 for ETOH abuse. +. +In the ED, initial VS: T96.6 HR 80 BP 108/73 RR16 100RA. He was +monitored overnight, but noted to be progressively more +tremulous and tachycardic. Also reported hallucinations. +Initially was threatening to leave AMA, but agreed to stay for +further treatment. Team unable to get PIVs so femoral line +placed for access. He received 50mg PO valium and 2mg of Ativan +IM since [**85**]:40 AM. +. +He was most recently admitted for EtOh withdrawal on [**11-9**] but +left AMA. He returned to the ED on [**11-13**] for intoxication and +was noted to have elevated amylase, lipase concerning for acute +pancreatitis. Again, pt signed out AMA. +. +On arrival to [**Hospital Unit Name 153**], patient was tremulous, complaining of pain +all over and felt like his ""skin was crawling."" Also reported +chronic abdominal pain over the last several months that he +attributed to excessive intake of listerine. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: Afebrile, BP 146/60, HR 114 RR 16 98%RA +GEN: Anxious, cooperative. +Neuro: AAO to person, place, time, situation. +- CN ii-xii intact +- motor [**6-11**] bilat upper/lower +- tremulous bilateral upper ext +- [**Last Name (un) 36**] to light touch intact +- toes downgoing bilaterally +- gait: not assessed as patient unsteady +HEENT: 1.5cm laceration with sutures and associated ecchymosis +and swelling of L eyebrow. Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non distended; mild tenderness throughout, hypoactive +BS +Ext: R femoral line C/D/I; no edema. good pulses +SKIN: No rashes + + +Pertinent Results: +[**2181-11-20**] 05:35AM BLOOD WBC-5.1 RBC-4.03* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.6 MCHC-34.1 RDW-14.8 Plt Ct-190 +[**2181-11-19**] 03:41AM BLOOD WBC-4.3 RBC-3.85* Hgb-11.6* Hct-33.3* +MCV-87 MCH-30.2 MCHC-34.8 RDW-15.5 Plt Ct-195 +[**2181-11-18**] 02:31PM BLOOD WBC-6.1 RBC-4.43* Hgb-13.2* Hct-37.8* +MCV-85 MCH-29.9 MCHC-35.0 RDW-16.0* Plt Ct-272# +[**2181-11-18**] 02:31PM BLOOD Neuts-32.6* Lymphs-57.1* Monos-6.0 +Eos-3.2 Baso-1.2 +[**2181-11-20**] 05:35AM BLOOD PT-12.0 PTT-33.4 INR(PT)-1.0 +[**2181-11-20**] 05:35AM BLOOD Glucose-93 UreaN-8 Creat-0.6 Na-136 K-3.8 +Cl-104 HCO3-24 AnGap-12 +[**2181-11-20**] 05:35AM BLOOD ALT-44* AST-72* LD(LDH)-286* +[**2181-11-20**] 05:35AM BLOOD Calcium-8.4 Phos-3.4 Mg-1.9 +[**2181-11-18**] 02:31PM BLOOD ASA-NEG Ethanol-137* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +36M with EtOH dependence and frequent admissions for EtOH +intoxication presents s/p fall with EtOH withdrawal. + +1. Alcohol withdrawal: No hypertension or tachycardia this +morning. Slightly agitated and with slight upper extremity +tremor. Has history of hx of DTs and w/d seizures. Patient was +treated with CIWA scale per prior admissions. On hospital day +3, patient signed out AMA. + +2. Fall: Patient with unwitnessed fall. Radiographs negative +for fracture. + +3. Abdominal pain: [**Month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of LFTs. + +4. Alcoholic liver disease: AST/ALT improving. No stigmata of +liver disease by physical exam. [**Doctor First Name **]/lipase normal. Also has +history of hepatitis B/C. + +5. Anemia: Normocytic anemia, at baseline. + +6. PPx: Patient treated with heparin SQ for dvt prophylaxis. + +7. Access: Patient with femoral CVL placed in ED. PICC placed +during admission, which was removed when patient signed out AMA. + +8. Dispo: Patient signed out AMA. + +Medications on Admission: +None + +Discharge Medications: +1. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +EtOH withdrawal + + +Discharge Condition: +Patient leaving against medical advice. + + +Discharge Instructions: +You were admitted for alcohol withdrawal and received +benzodiazepines to manage your withdrawal. We recommended +transfer to the regular medical floor from the ICU for continued +management of your withdrawal symptoms, but you have decided to +leave against our medical advice. + +Followup Instructions: +Please follow up with your primary care doctor within the next +few days. You should also seek care for substance abuse. + + + +Completed by:[**2181-11-20**]",24,2181-11-18 06:42:00,2181-11-20 12:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALTERED MENTAL STATUS," +36m with etoh dependence and frequent admissions for etoh +intoxication presents s/p fall with etoh withdrawal. + +1. alcohol withdrawal: no hypertension or tachycardia this +morning. slightly agitated and with slight upper extremity +tremor. has history of hx of dts and w/d seizures. patient was +treated with ciwa scale per prior admissions. on hospital day +3, patient signed out ama. + +2. fall: patient with unwitnessed fall. radiographs negative +for fracture. + +3. abdominal pain: [**month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of lfts. + +4. alcoholic liver disease: ast/alt improving. no stigmata of +liver disease by physical exam. [**doctor first name **]/lipase normal. also has +history of hepatitis b/c. + +5. anemia: normocytic anemia, at baseline. + +6. ppx: patient treated with heparin sq for dvt prophylaxis. + +7. access: patient with femoral cvl placed in ed. picc placed +during admission, which was removed when patient signed out ama. + +8. dispo: patient signed out ama. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Open wound of forehead, without mention of complication; Unspecified fall; Chronic hepatitis C without mention of hepatic coma; Lack of housing; Anemia, unspecified; Acute alcoholic hepatitis; Alcoholic gastritis, without mention of hemorrhage; Hypovolemia]" +5060,135773.0,24304,2181-12-14,24303,197750.0,2181-12-11,Discharge summary,"Admission Date: [**2181-12-7**] Discharge Date: [**2181-12-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 8487**] +Chief Complaint: +ETOH Withdrawal, Chest, Abdominal, Arm and Hand Pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +37yoM with hx of polysubstance abuse, frequent ICU admissions +and ED evals returns with alcohol intoxication and withdrawal. +Pt reports currently using ETOH, and presenting for pain from a +reported trauma approx 4 days ago at which time the patient +reports being hit by a SUV. He states he signed out AMA from the +[**Hospital1 3278**] ICU after this accident. Pt with a hx of withdrawal +seizures as well as Section 35/Section 12 for ETOH abuse. The +patient reports being acutely intoxicated currently, and most +recently, drinking Listerine this am. Today the patient was +found lying next to [**Company 2486**] where EMS was called and we +has brought to the ED. Since leaving [**Hospital1 3278**] he has spent the past +few days at [**Location (un) 7073**] Station, drinking Vodka during the day and +Listerine at night ""to prevent seizures"". He believes his last +seizure occurred three weeks ago. He notes pain all over his +body - esp in his hands, chest, abdomen and legs. +. +In the ED, initial VS 98.3 120/88 116 16 100%2L: In the E.D. he +received Morphine 6mg, Valium 50mg, Gabapentin 600mg, Toradol +30mg, 1 banana bag and 2 additional L of NS. He was monitored, +but noted to be progressively more tremulous, tachycardic and +reporting visual hallucinations. +. +Of note the pt has had recent admissions for EtOh withdrawal on +[**11-9**] but left AMA. He returned to the ED on [**11-13**] for +intoxication and was noted to have elevated amylase, lipase +concerning for acute pancreatitis. Again, pt signed out AMA. The +pt was admitted on [**11-18**], again for acute EtOH withdrwal, and +signed out AMA on [**11-20**]. +. +On arrival to [**Hospital Unit Name 153**]: Pt tremulous, anxious, tachy to 110s, with +some visual hallucinations, however not hypertensive or febrile. +Pt denies fever, + chills, headache. Admits to chronic abdominal +pain of [**8-14**] months duration. Pt also admits to chest pain of one +weeks duration since being hit by a car. Pt also noted recent +episodes of epistaxis, although none within the past few days. +. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C (Diagnosed around [**2163**], Never treated) +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 98.7 113/77 89 98 3LNC +GEN: Anxious, cooperative. Alert to date, name but not to +location +HEENT: PERRLA Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non-distended; mild tenderness throughout, hypoactive +BS +Ext: 1+ Bilateral upper extremity edema. good pulses +SKIN: No rashes +Neuro: AOx2, (not location), CN II-XII intact, Motor [**6-11**] bilat, +Tremulous bilateral upper ext + + +Pertinent Results: +Admission labs +[**2181-12-7**] 05:35PM BLOOD WBC-3.5* RBC-3.97* Hgb-11.8* Hct-34.7* +MCV-87 MCH-29.7 MCHC-34.0 RDW-15.4 Plt Ct-308# +[**2181-12-7**] 05:35PM BLOOD Neuts-33.4* Bands-0 Lymphs-57.1* +Monos-5.0 Eos-3.2 Baso-1.3 +[**2181-12-7**] 05:35PM BLOOD PT-13.3 PTT-29.8 INR(PT)-1.1 +[**2181-12-7**] 05:35PM BLOOD Glucose-198* UreaN-7 Creat-0.8 Na-143 +K-3.8 Cl-102 HCO3-25 AnGap-20 +[**2181-12-7**] 05:35PM BLOOD ALT-52* AST-101* CK(CPK)-359* AlkPhos-83 +[**2181-12-7**] 05:35PM BLOOD Lipase-135* +[**2181-12-7**] 05:35PM BLOOD Albumin-4.3 +[**2181-12-9**] 04:24AM BLOOD TSH-3.1 +[**2181-12-7**] 05:35PM BLOOD ASA-NEG Ethanol-396* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +[**2181-12-7**]: CXR IMPRESSION: No acute cardiopulmonary abnormality. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with ETOH dependence and frequent +admissions for EtOH intoxication who presents with EtOH +withdrawal and global pain. +. +# EtoH Withdrawal:On admission, the pt was A0x2. Throughout his +ICU stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. CIWAs 16-29. However, it +is also notable that he knows how to manipulate the CIWA and +would frequently do so in order to get increasing amounts of +benzodiazepines. On [**12-11**], his CIWA was discontinued and he was +told he would be transferred to the floor at which point he +signout AMA. While here, he was given thiamine, MVI, folate and +PRN electrolytes. +. +# Abdominal and Chest pain: DDx includes recent trauma (although +nothing apparent on exam), acute EtOh hepatitis, pancreatitis, +though minimal elevation of LFTs. Less likely cardiac given +reproducible nature, and unchanged EKG. No fever or leukocytosis +at this time. Lipase slightly increased from [**11-18**] (135 from +56). No evidence of ascites on recent Abd U/S. Troponins were +trended. He was given oxycodone 5-10mg Q 4hrs PRN. +. +# Alcoholic liver disease: AST/ALT elevated in 2:1 ratio, this +is his baseline. No stigmata of liver disease by physical exam. +Lipase 135 normal. INR 1.1. No scopes in [**Hospital1 **] records. LFTs and +coags were monitored. +. +# Anemia - Iron deficiency anemia baseline per [**11-9**] labs with +Ferritin of 11. Hct drop from 34 to 28 in setting of 3L IVF upon +admission. No active signs of bleeding, likely diluational. Hct +was monitored, pt was given po iron, folate and thiamine. + + +Medications on Admission: +None + +Discharge Medications: +Pt was not given medications nor discharge instructions as he +left AMA on the morning of [**2181-12-11**]. + +Discharge Disposition: +Home + +Discharge Diagnosis: +. + +Discharge Condition: +. + +Discharge Instructions: +. + +Followup Instructions: +. + + +Completed by:[**2182-1-10**]",3,2181-12-08 19:58:00,2181-12-11 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with etoh dependence and frequent +admissions for etoh intoxication who presents with etoh +withdrawal and global pain. +. +# etoh withdrawal:on admission, the pt was a0x2. throughout his +icu stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. ciwas 16-29. however, it +is also notable that he knows how to manipulate the ciwa and +would frequently do so in order to get increasing amounts of +benzodiazepines. on [**12-11**], his ciwa was discontinued and he was +told he would be transferred to the floor at which point he +signout ama. while here, he was given thiamine, mvi, folate and +prn electrolytes. +. +# abdominal and chest pain: ddx includes recent trauma (although +nothing apparent on exam), acute etoh hepatitis, pancreatitis, +though minimal elevation of lfts. less likely cardiac given +reproducible nature, and unchanged ekg. no fever or leukocytosis +at this time. lipase slightly increased from [**11-18**] (135 from +56). no evidence of ascites on recent abd u/s. troponins were +trended. he was given oxycodone 5-10mg q 4hrs prn. +. +# alcoholic liver disease: ast/alt elevated in 2:1 ratio, this +is his baseline. no stigmata of liver disease by physical exam. +lipase 135 normal. inr 1.1. no scopes in [**hospital1 **] records. lfts and +coags were monitored. +. +# anemia - iron deficiency anemia baseline per [**11-9**] labs with +ferritin of 11. hct drop from 34 to 28 in setting of 3l ivf upon +admission. no active signs of bleeding, likely diluational. hct +was monitored, pt was given po iron, folate and thiamine. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Lack of housing]" +5060,184857.0,24302,2181-11-20,24300,194191.0,2181-08-21,Discharge summary,"Admission Date: [**2181-8-20**] Discharge Date: [**2181-8-21**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2485**] +Chief Complaint: +etoh w/d + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +36 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions returns with alcohol intoxication. He +reports that he has been drinking daily since being released +from prison on [**7-10**]. He drinks enough vodka or listerine so +that he blacks out daily. He believes he was brought in by EMS +or a local after he was found intoxicated. Per ED reports, he +was BIBA after being found down. + +He was most recently admitted for EtOh withdrawal from [**2-24**] - +[**3-5**] and left AMA after his valium dose was tapered. He returned +on [**7-4**] with a fall but was discharged from the ED after a +negative head CT. +. +ED: VS on arrival 98.5 114 128/62 16 97% RA. Tox was negative +for cocaine, amphetamines. Serum tox was positive for etoh 448 +and benzos. Had anion gap of 18 but VBG of 7.49/33/58 and +lactate of 3.1. We was given 60-70 IV valium for withdrawal sx +of agitation, hypertension, and tachycardia. Also received 3L +IVF. +. +Currently, the patient reports having chest pain x1wk. he +thinks he was punched in the chest and has since had +intermittently dull/sharp nonradiating substernal chest pain. +Now it is [**9-16**] and sharp. It is not exertional nor assoc with +SOB or diaphoresis/n/v. Worse w palpation. Also reports +falling and hitting right forehead 10d ago. Has had no fevers +or residual HA since that time. +. +ROS otherwise pos for URI-like sx. no diarrhea. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures - once sent under +section 35 to prison due to concern that he was a severe threat +to himself with his drinking. required intubation in the past. +- has been seen recently by psychiatry in the past to evaluate +for possible section 35. + +Social History: +Drinks regularly, prefers listerine and vodka. Has been +drinking heavily since release from prison on [**8-9**]. +Homeless, lives on streets. Denies IVDU for >10yrs. Denies +cigs for>10 yrs. Denies SI or HI + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 99.8 110 96% RA RR12 133/111 +gen: agitated but redirectable. +Neuro: aao to person, place, time, situation. +- cn ii-xii intact +- motor [**6-11**] bilat upper/lower +- slightly tremulous upper ex +- [**Last Name (un) 36**] to light touch +- gait wide based and unsteady +- f-n intact bilat +- h-s impaired bilat +heent: old scar on right forehead. mm dry, jvp flat +cards: tachy, reg, no murmurs +resp: ctab +abd: BS+ NT ND soft, no rebound, no stigmata of liver dz +Ext: no edema. good pulses + +Pertinent Results: +EKG: Sinus tachy, nl axis, nl intervals, no acute st-t changes. +. +Labs: +VBG: 7.49/33/58 +Lactate 3.1 +. +142 102 10 +----------------< 87 +4.1 22 0.9 +Ca: 9.4 Mg: 2.0 P: 2.9 +Serum EtOH 448 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +. +WBC: 9.5 +HCT: 35.7 - at baseline +PLT: 208 +N:64.2 L:30.8 M:3.5 E:1.1 Bas:0.5 +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Repeat chemistry: +140 108 8 +-------------< 73 +3.3 20 0.7 +Ca: 8.0 Mg: 1.6 P: 1.9 +repeat lactate 3.1 + +Brief Hospital Course: +36M with ETOH dependence and frequent admissions for EtOH +intoxication presents with EtOH withdrawal. ICU-east course by +problem: +. +# Alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. Has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of DTs and w/d seizures, we treated +aggressively with valium in ICU. He received either 60-70 IV +valium in the ED. On arrival to the ICU, he was written for +valium 20mg PO q15m prn CIWA>10 and he received it almost as +frequently as written. He became less agitated after approx +80-100mg (in addition to the IV given in the ED) and then the +CIWA scale was spread out to 20mg PO prn q1h. He tolerated +this transition well. +- He received multivit, folate, thiamine in IVF then PO +- social work was consulted the morning after admission when +patient was demanding to leave. He felt he had enough valium +and actually refused another dose. We explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. He expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. He signed out +AMA with plans to seek outpatient treatment. +. +# Psych: No SI. We had plans to contact psychiatry morning +after admission particularly given his high valium need. +However, he expressed interest in leaving and we felt he had +capacity to make this decision. Social wk was involved but +psychiatry was not consulted. +. +# chest pain: EKG without ischemic changes. CP was reproducible +on palpation. Suspected MSK pain. He received one dose of +morphine for cp. We then treated with toradol, motrin, and +tylenol. We would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. His pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. Lactic acidosis not likely +given the alkalosis seen on VBG. Consider dehydration vs poor +quality sample. Infection less likely given no fever or +hypotension or any localizing signs of infection. Repeat +lactate remained 3.1. Etiology unclear and workup hindered by +patient leaving AMA. +. +# Anion gap: AG 18 in the ED with a normal HCO3 and alkalosis on +VBG. ASA negative as were other toxins. Difficult to interpret +but wonder if slightly increased AG is from the elevated +lactate. Repeat chemistries showed normal anion gap. +. +#Anemia - normocytic anemia, Hct at baseline +. +# PPx: Heparin sc tid, PPI given etoh abuse, bowel reg +. +# FEN: Regular diet, replete lytes prn, banana bag then IVF +. +# Access: PIV x1 +. +# Code: FULL +. +# Communication: Patient +. +# Dispo: Patient left AMA. + + +Medications on Admission: +none + +Discharge Medications: +none + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH Intoxication/Withdrawal + + +Discharge Condition: +fair + + +Discharge Instructions: +You were admitted to the hospital because you were found +intoxicated by EMS. You were admitted to the ICU and treated +with Valium for withdrawal. You were advised to stay in the +hospital for continued care and treatment of withdrawal however +you decided against medical advice that you no longer wished to +receive care. You spoke with the social worker before you left +the hospital and were advised to return to [**Street Address(1) 5904**] Inn +to speak with your outreach worker there. + +You signed out against medical advise. + +Followup Instructions: +Please speak with the Outreach worker [**Street Address(1) 29735**] Inn. + +Please return to the hospital should you have any concerning +symptoms including difficulty breathing, falls or injuries +requiring medical attention, concerning withdrawal symptoms. + + + +",91,2181-08-20 20:26:00,2181-08-21 11:10:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +36m with etoh dependence and frequent admissions for etoh +intoxication presents with etoh withdrawal. icu-east course by +problem: +. +# alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of dts and w/d seizures, we treated +aggressively with valium in icu. he received either 60-70 iv +valium in the ed. on arrival to the icu, he was written for +valium 20mg po q15m prn ciwa>10 and he received it almost as +frequently as written. he became less agitated after approx +80-100mg (in addition to the iv given in the ed) and then the +ciwa scale was spread out to 20mg po prn q1h. he tolerated +this transition well. +- he received multivit, folate, thiamine in ivf then po +- social work was consulted the morning after admission when +patient was demanding to leave. he felt he had enough valium +and actually refused another dose. we explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. he expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. he signed out +ama with plans to seek outpatient treatment. +. +# psych: no si. we had plans to contact psychiatry morning +after admission particularly given his high valium need. +however, he expressed interest in leaving and we felt he had +capacity to make this decision. social wk was involved but +psychiatry was not consulted. +. +# chest pain: ekg without ischemic changes. cp was reproducible +on palpation. suspected msk pain. he received one dose of +morphine for cp. we then treated with toradol, motrin, and +tylenol. we would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. his pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. lactic acidosis not likely +given the alkalosis seen on vbg. consider dehydration vs poor +quality sample. infection less likely given no fever or +hypotension or any localizing signs of infection. repeat +lactate remained 3.1. etiology unclear and workup hindered by +patient leaving ama. +. +# anion gap: ag 18 in the ed with a normal hco3 and alkalosis on +vbg. asa negative as were other toxins. difficult to interpret +but wonder if slightly increased ag is from the elevated +lactate. repeat chemistries showed normal anion gap. +. +#anemia - normocytic anemia, hct at baseline +. +# ppx: heparin sc tid, ppi given etoh abuse, bowel reg +. +# fen: regular diet, replete lytes prn, banana bag then ivf +. +# access: piv x1 +. +# code: full +. +# communication: patient +. +# dispo: patient left ama. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Alkalosis; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Acidosis; Chronic hepatitis C without mention of hepatic coma; Cocaine abuse, unspecified; Lack of housing; Anemia, unspecified; Other chest pain]" +5060,184857.0,24302,2181-11-20,24301,153063.0,2181-10-24,Discharge summary,"Admission Date: [**2181-10-23**] Discharge Date: [**2181-10-24**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5893**] +Chief Complaint: +CC:[**CC Contact Info 61604**] +Major Surgical or Invasive Procedure: +none + +History of Present Illness: + +HPI: 37YO man with long hx of alcohol abuse, with frequent ED +visits/hospitalizations for same was brought to the ED today +after being found by EMS sleeping on street. He reports drinking +[**2-8**] pints of vodka daily. He eats very little. He also drinks +listerine each night. He reports frequent falls (recent scalp +lac w/ staples; abrasion over face). His ETOH level was 434 at +10:00 AM. He was given Ativan 2 mg at 6:30 in the ED for CIWA +=13; then given Ativan 2 mg at 6:30pm for CIWA = 23. He was +admitted to the floor for EtOH withdrawal. +. +On arrival to the floor, the patient was given Valium 10 mg PO +and 10 mg IV over 40 minutes without improvement in his CIWA. +He is transferred to the ICU for further management. +. +Of note, previous admission in [**Month (only) 205**] for ETOH withdrawal pt +required 20mg PO valium q15min, then left AMA. +. +Pt not cooperative for further ROS. +. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Currently reports drinking ""at least"" a lint of vodka each +morning and listerine each evening. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration +for possession, estranged from family, never married, no +children, homeless + +Family History: +Possible OCD in his father. + +Physical Exam: +Vitals: 99.3, 110/64, 115, 18, 99% RA +GEN: diaphoretic, sitting in bed, anxious +HEENT:hematoma on R occipital area where staples removed last +week. scabb on bridge of nose and R temple. PERRLA 5mm->2mm, +EOMI, throat non-erythematous, poor dentition, MMM +Lungs: clear +CV: tachy, rrr +Abd: + bs soft, limited exam, no focal tenderness +ext: + tremor, no c/c/e + + +Pertinent Results: +Labs: +. +143 /103 / 11 /140 Ca: 8.8 Mg: 2.1 P: 3.3 +-------------- +3.9 /31 / 0.8 + +. +4.7 / 13.0 / 315 N:35.4 L:50.6 M:4.4 E:7.8 Bas:1.8 + ------- + 39.6 +. +Serum EtOH 434, Serum Benzo Pos, +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Urine Benzos Pos +Urine Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Imaging: None + + +Brief Hospital Course: +In summary, Mr. [**Known lastname 24927**] is a 37 yo male with history of ETOH +abuse presents with acute ETOH intoxication. +. +ETOH abuse. Patient has a long history of alcohol abuse, with +innumerable ED visits and hospitalizations for same. Patient +was initially on diazepam CIWA scale. Within twelve hours of +admission, patient was requesting to leave AMA. He was +evaluated by psychiatry who felt he had competence to leave AMA. + He was not a candidate for section 35. Risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + +Medications on Admission: +None + +Discharge Medications: +None. Patient left AMA. + +Discharge Disposition: +Home + +Facility: +AMA + +Discharge Diagnosis: +Alcohol abuse. + +Discharge Condition: +AMA + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + +",27,2181-10-23 18:54:00,2181-10-24 15:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +in summary, mr. [**known lastname 24927**] is a 37 yo male with history of etoh +abuse presents with acute etoh intoxication. +. +etoh abuse. patient has a long history of alcohol abuse, with +innumerable ed visits and hospitalizations for same. patient +was initially on diazepam ciwa scale. within twelve hours of +admission, patient was requesting to leave ama. he was +evaluated by psychiatry who felt he had competence to leave ama. + he was not a candidate for section 35. risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing]" +5060,170299.0,24306,2182-04-01,24301,153063.0,2181-10-24,Discharge summary,"Admission Date: [**2181-10-23**] Discharge Date: [**2181-10-24**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5893**] +Chief Complaint: +CC:[**CC Contact Info 61604**] +Major Surgical or Invasive Procedure: +none + +History of Present Illness: + +HPI: 37YO man with long hx of alcohol abuse, with frequent ED +visits/hospitalizations for same was brought to the ED today +after being found by EMS sleeping on street. He reports drinking +[**2-8**] pints of vodka daily. He eats very little. He also drinks +listerine each night. He reports frequent falls (recent scalp +lac w/ staples; abrasion over face). His ETOH level was 434 at +10:00 AM. He was given Ativan 2 mg at 6:30 in the ED for CIWA +=13; then given Ativan 2 mg at 6:30pm for CIWA = 23. He was +admitted to the floor for EtOH withdrawal. +. +On arrival to the floor, the patient was given Valium 10 mg PO +and 10 mg IV over 40 minutes without improvement in his CIWA. +He is transferred to the ICU for further management. +. +Of note, previous admission in [**Month (only) 205**] for ETOH withdrawal pt +required 20mg PO valium q15min, then left AMA. +. +Pt not cooperative for further ROS. +. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Currently reports drinking ""at least"" a lint of vodka each +morning and listerine each evening. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration +for possession, estranged from family, never married, no +children, homeless + +Family History: +Possible OCD in his father. + +Physical Exam: +Vitals: 99.3, 110/64, 115, 18, 99% RA +GEN: diaphoretic, sitting in bed, anxious +HEENT:hematoma on R occipital area where staples removed last +week. scabb on bridge of nose and R temple. PERRLA 5mm->2mm, +EOMI, throat non-erythematous, poor dentition, MMM +Lungs: clear +CV: tachy, rrr +Abd: + bs soft, limited exam, no focal tenderness +ext: + tremor, no c/c/e + + +Pertinent Results: +Labs: +. +143 /103 / 11 /140 Ca: 8.8 Mg: 2.1 P: 3.3 +-------------- +3.9 /31 / 0.8 + +. +4.7 / 13.0 / 315 N:35.4 L:50.6 M:4.4 E:7.8 Bas:1.8 + ------- + 39.6 +. +Serum EtOH 434, Serum Benzo Pos, +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Urine Benzos Pos +Urine Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Imaging: None + + +Brief Hospital Course: +In summary, Mr. [**Known lastname 24927**] is a 37 yo male with history of ETOH +abuse presents with acute ETOH intoxication. +. +ETOH abuse. Patient has a long history of alcohol abuse, with +innumerable ED visits and hospitalizations for same. Patient +was initially on diazepam CIWA scale. Within twelve hours of +admission, patient was requesting to leave AMA. He was +evaluated by psychiatry who felt he had competence to leave AMA. + He was not a candidate for section 35. Risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + +Medications on Admission: +None + +Discharge Medications: +None. Patient left AMA. + +Discharge Disposition: +Home + +Facility: +AMA + +Discharge Diagnosis: +Alcohol abuse. + +Discharge Condition: +AMA + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + +",159,2181-10-23 18:54:00,2181-10-24 15:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +in summary, mr. [**known lastname 24927**] is a 37 yo male with history of etoh +abuse presents with acute etoh intoxication. +. +etoh abuse. patient has a long history of alcohol abuse, with +innumerable ed visits and hospitalizations for same. patient +was initially on diazepam ciwa scale. within twelve hours of +admission, patient was requesting to leave ama. he was +evaluated by psychiatry who felt he had competence to leave ama. + he was not a candidate for section 35. risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing]" +5060,170299.0,24306,2182-04-01,24302,184857.0,2181-11-20,Discharge summary,"Admission Date: [**2181-11-18**] Discharge Date: [**2181-11-20**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +ETOH Withdrawal + +Major Surgical or Invasive Procedure: +PICC placement ([**2181-11-19**]) + +History of Present Illness: +37 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions and ED evals returns with alcohol +intoxication and withdrawal. Presented to ED s/p unwitnessed +fall while intoxicated. Came in c/o L elbow and R hand pain. +Also with left supraorbital laceration that was repaired in the +ED. He reports currently drinking 1 bottle of Vodka and large +bottle of mouthwash daily. He has a hx of withdrawal seizures as +well as Section 35/Section 12 for ETOH abuse. +. +In the ED, initial VS: T96.6 HR 80 BP 108/73 RR16 100RA. He was +monitored overnight, but noted to be progressively more +tremulous and tachycardic. Also reported hallucinations. +Initially was threatening to leave AMA, but agreed to stay for +further treatment. Team unable to get PIVs so femoral line +placed for access. He received 50mg PO valium and 2mg of Ativan +IM since [**85**]:40 AM. +. +He was most recently admitted for EtOh withdrawal on [**11-9**] but +left AMA. He returned to the ED on [**11-13**] for intoxication and +was noted to have elevated amylase, lipase concerning for acute +pancreatitis. Again, pt signed out AMA. +. +On arrival to [**Hospital Unit Name 153**], patient was tremulous, complaining of pain +all over and felt like his ""skin was crawling."" Also reported +chronic abdominal pain over the last several months that he +attributed to excessive intake of listerine. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: Afebrile, BP 146/60, HR 114 RR 16 98%RA +GEN: Anxious, cooperative. +Neuro: AAO to person, place, time, situation. +- CN ii-xii intact +- motor [**6-11**] bilat upper/lower +- tremulous bilateral upper ext +- [**Last Name (un) 36**] to light touch intact +- toes downgoing bilaterally +- gait: not assessed as patient unsteady +HEENT: 1.5cm laceration with sutures and associated ecchymosis +and swelling of L eyebrow. Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non distended; mild tenderness throughout, hypoactive +BS +Ext: R femoral line C/D/I; no edema. good pulses +SKIN: No rashes + + +Pertinent Results: +[**2181-11-20**] 05:35AM BLOOD WBC-5.1 RBC-4.03* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.6 MCHC-34.1 RDW-14.8 Plt Ct-190 +[**2181-11-19**] 03:41AM BLOOD WBC-4.3 RBC-3.85* Hgb-11.6* Hct-33.3* +MCV-87 MCH-30.2 MCHC-34.8 RDW-15.5 Plt Ct-195 +[**2181-11-18**] 02:31PM BLOOD WBC-6.1 RBC-4.43* Hgb-13.2* Hct-37.8* +MCV-85 MCH-29.9 MCHC-35.0 RDW-16.0* Plt Ct-272# +[**2181-11-18**] 02:31PM BLOOD Neuts-32.6* Lymphs-57.1* Monos-6.0 +Eos-3.2 Baso-1.2 +[**2181-11-20**] 05:35AM BLOOD PT-12.0 PTT-33.4 INR(PT)-1.0 +[**2181-11-20**] 05:35AM BLOOD Glucose-93 UreaN-8 Creat-0.6 Na-136 K-3.8 +Cl-104 HCO3-24 AnGap-12 +[**2181-11-20**] 05:35AM BLOOD ALT-44* AST-72* LD(LDH)-286* +[**2181-11-20**] 05:35AM BLOOD Calcium-8.4 Phos-3.4 Mg-1.9 +[**2181-11-18**] 02:31PM BLOOD ASA-NEG Ethanol-137* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +36M with EtOH dependence and frequent admissions for EtOH +intoxication presents s/p fall with EtOH withdrawal. + +1. Alcohol withdrawal: No hypertension or tachycardia this +morning. Slightly agitated and with slight upper extremity +tremor. Has history of hx of DTs and w/d seizures. Patient was +treated with CIWA scale per prior admissions. On hospital day +3, patient signed out AMA. + +2. Fall: Patient with unwitnessed fall. Radiographs negative +for fracture. + +3. Abdominal pain: [**Month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of LFTs. + +4. Alcoholic liver disease: AST/ALT improving. No stigmata of +liver disease by physical exam. [**Doctor First Name **]/lipase normal. Also has +history of hepatitis B/C. + +5. Anemia: Normocytic anemia, at baseline. + +6. PPx: Patient treated with heparin SQ for dvt prophylaxis. + +7. Access: Patient with femoral CVL placed in ED. PICC placed +during admission, which was removed when patient signed out AMA. + +8. Dispo: Patient signed out AMA. + +Medications on Admission: +None + +Discharge Medications: +1. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +EtOH withdrawal + + +Discharge Condition: +Patient leaving against medical advice. + + +Discharge Instructions: +You were admitted for alcohol withdrawal and received +benzodiazepines to manage your withdrawal. We recommended +transfer to the regular medical floor from the ICU for continued +management of your withdrawal symptoms, but you have decided to +leave against our medical advice. + +Followup Instructions: +Please follow up with your primary care doctor within the next +few days. You should also seek care for substance abuse. + + + +Completed by:[**2181-11-20**]",132,2181-11-18 06:42:00,2181-11-20 12:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALTERED MENTAL STATUS," +36m with etoh dependence and frequent admissions for etoh +intoxication presents s/p fall with etoh withdrawal. + +1. alcohol withdrawal: no hypertension or tachycardia this +morning. slightly agitated and with slight upper extremity +tremor. has history of hx of dts and w/d seizures. patient was +treated with ciwa scale per prior admissions. on hospital day +3, patient signed out ama. + +2. fall: patient with unwitnessed fall. radiographs negative +for fracture. + +3. abdominal pain: [**month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of lfts. + +4. alcoholic liver disease: ast/alt improving. no stigmata of +liver disease by physical exam. [**doctor first name **]/lipase normal. also has +history of hepatitis b/c. + +5. anemia: normocytic anemia, at baseline. + +6. ppx: patient treated with heparin sq for dvt prophylaxis. + +7. access: patient with femoral cvl placed in ed. picc placed +during admission, which was removed when patient signed out ama. + +8. dispo: patient signed out ama. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Open wound of forehead, without mention of complication; Unspecified fall; Chronic hepatitis C without mention of hepatic coma; Lack of housing; Anemia, unspecified; Acute alcoholic hepatitis; Alcoholic gastritis, without mention of hemorrhage; Hypovolemia]" +5060,170299.0,24306,2182-04-01,24303,197750.0,2181-12-11,Discharge summary,"Admission Date: [**2181-12-7**] Discharge Date: [**2181-12-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 8487**] +Chief Complaint: +ETOH Withdrawal, Chest, Abdominal, Arm and Hand Pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +37yoM with hx of polysubstance abuse, frequent ICU admissions +and ED evals returns with alcohol intoxication and withdrawal. +Pt reports currently using ETOH, and presenting for pain from a +reported trauma approx 4 days ago at which time the patient +reports being hit by a SUV. He states he signed out AMA from the +[**Hospital1 3278**] ICU after this accident. Pt with a hx of withdrawal +seizures as well as Section 35/Section 12 for ETOH abuse. The +patient reports being acutely intoxicated currently, and most +recently, drinking Listerine this am. Today the patient was +found lying next to [**Company 2486**] where EMS was called and we +has brought to the ED. Since leaving [**Hospital1 3278**] he has spent the past +few days at [**Location (un) 7073**] Station, drinking Vodka during the day and +Listerine at night ""to prevent seizures"". He believes his last +seizure occurred three weeks ago. He notes pain all over his +body - esp in his hands, chest, abdomen and legs. +. +In the ED, initial VS 98.3 120/88 116 16 100%2L: In the E.D. he +received Morphine 6mg, Valium 50mg, Gabapentin 600mg, Toradol +30mg, 1 banana bag and 2 additional L of NS. He was monitored, +but noted to be progressively more tremulous, tachycardic and +reporting visual hallucinations. +. +Of note the pt has had recent admissions for EtOh withdrawal on +[**11-9**] but left AMA. He returned to the ED on [**11-13**] for +intoxication and was noted to have elevated amylase, lipase +concerning for acute pancreatitis. Again, pt signed out AMA. The +pt was admitted on [**11-18**], again for acute EtOH withdrwal, and +signed out AMA on [**11-20**]. +. +On arrival to [**Hospital Unit Name 153**]: Pt tremulous, anxious, tachy to 110s, with +some visual hallucinations, however not hypertensive or febrile. +Pt denies fever, + chills, headache. Admits to chronic abdominal +pain of [**8-14**] months duration. Pt also admits to chest pain of one +weeks duration since being hit by a car. Pt also noted recent +episodes of epistaxis, although none within the past few days. +. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C (Diagnosed around [**2163**], Never treated) +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 98.7 113/77 89 98 3LNC +GEN: Anxious, cooperative. Alert to date, name but not to +location +HEENT: PERRLA Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non-distended; mild tenderness throughout, hypoactive +BS +Ext: 1+ Bilateral upper extremity edema. good pulses +SKIN: No rashes +Neuro: AOx2, (not location), CN II-XII intact, Motor [**6-11**] bilat, +Tremulous bilateral upper ext + + +Pertinent Results: +Admission labs +[**2181-12-7**] 05:35PM BLOOD WBC-3.5* RBC-3.97* Hgb-11.8* Hct-34.7* +MCV-87 MCH-29.7 MCHC-34.0 RDW-15.4 Plt Ct-308# +[**2181-12-7**] 05:35PM BLOOD Neuts-33.4* Bands-0 Lymphs-57.1* +Monos-5.0 Eos-3.2 Baso-1.3 +[**2181-12-7**] 05:35PM BLOOD PT-13.3 PTT-29.8 INR(PT)-1.1 +[**2181-12-7**] 05:35PM BLOOD Glucose-198* UreaN-7 Creat-0.8 Na-143 +K-3.8 Cl-102 HCO3-25 AnGap-20 +[**2181-12-7**] 05:35PM BLOOD ALT-52* AST-101* CK(CPK)-359* AlkPhos-83 +[**2181-12-7**] 05:35PM BLOOD Lipase-135* +[**2181-12-7**] 05:35PM BLOOD Albumin-4.3 +[**2181-12-9**] 04:24AM BLOOD TSH-3.1 +[**2181-12-7**] 05:35PM BLOOD ASA-NEG Ethanol-396* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +[**2181-12-7**]: CXR IMPRESSION: No acute cardiopulmonary abnormality. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with ETOH dependence and frequent +admissions for EtOH intoxication who presents with EtOH +withdrawal and global pain. +. +# EtoH Withdrawal:On admission, the pt was A0x2. Throughout his +ICU stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. CIWAs 16-29. However, it +is also notable that he knows how to manipulate the CIWA and +would frequently do so in order to get increasing amounts of +benzodiazepines. On [**12-11**], his CIWA was discontinued and he was +told he would be transferred to the floor at which point he +signout AMA. While here, he was given thiamine, MVI, folate and +PRN electrolytes. +. +# Abdominal and Chest pain: DDx includes recent trauma (although +nothing apparent on exam), acute EtOh hepatitis, pancreatitis, +though minimal elevation of LFTs. Less likely cardiac given +reproducible nature, and unchanged EKG. No fever or leukocytosis +at this time. Lipase slightly increased from [**11-18**] (135 from +56). No evidence of ascites on recent Abd U/S. Troponins were +trended. He was given oxycodone 5-10mg Q 4hrs PRN. +. +# Alcoholic liver disease: AST/ALT elevated in 2:1 ratio, this +is his baseline. No stigmata of liver disease by physical exam. +Lipase 135 normal. INR 1.1. No scopes in [**Hospital1 **] records. LFTs and +coags were monitored. +. +# Anemia - Iron deficiency anemia baseline per [**11-9**] labs with +Ferritin of 11. Hct drop from 34 to 28 in setting of 3L IVF upon +admission. No active signs of bleeding, likely diluational. Hct +was monitored, pt was given po iron, folate and thiamine. + + +Medications on Admission: +None + +Discharge Medications: +Pt was not given medications nor discharge instructions as he +left AMA on the morning of [**2181-12-11**]. + +Discharge Disposition: +Home + +Discharge Diagnosis: +. + +Discharge Condition: +. + +Discharge Instructions: +. + +Followup Instructions: +. + + +Completed by:[**2182-1-10**]",111,2181-12-08 19:58:00,2181-12-11 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with etoh dependence and frequent +admissions for etoh intoxication who presents with etoh +withdrawal and global pain. +. +# etoh withdrawal:on admission, the pt was a0x2. throughout his +icu stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. ciwas 16-29. however, it +is also notable that he knows how to manipulate the ciwa and +would frequently do so in order to get increasing amounts of +benzodiazepines. on [**12-11**], his ciwa was discontinued and he was +told he would be transferred to the floor at which point he +signout ama. while here, he was given thiamine, mvi, folate and +prn electrolytes. +. +# abdominal and chest pain: ddx includes recent trauma (although +nothing apparent on exam), acute etoh hepatitis, pancreatitis, +though minimal elevation of lfts. less likely cardiac given +reproducible nature, and unchanged ekg. no fever or leukocytosis +at this time. lipase slightly increased from [**11-18**] (135 from +56). no evidence of ascites on recent abd u/s. troponins were +trended. he was given oxycodone 5-10mg q 4hrs prn. +. +# alcoholic liver disease: ast/alt elevated in 2:1 ratio, this +is his baseline. no stigmata of liver disease by physical exam. +lipase 135 normal. inr 1.1. no scopes in [**hospital1 **] records. lfts and +coags were monitored. +. +# anemia - iron deficiency anemia baseline per [**11-9**] labs with +ferritin of 11. hct drop from 34 to 28 in setting of 3l ivf upon +admission. no active signs of bleeding, likely diluational. hct +was monitored, pt was given po iron, folate and thiamine. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Lack of housing]" +5060,170299.0,24306,2182-04-01,24304,135773.0,2181-12-14,Discharge summary,"Admission Date: [**2181-12-12**] Discharge Date: [**2181-12-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +abdominal pain, alcohol withdrawal + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +HPI: 37 yo M with PMH of alcohol abuse with many admissions for +intoxication, hepatitis B and C who was brought in by the police +after being found intoxicated. He originally did not complain of +any pain or other problems. Of note, he was left AMA [**2181-12-11**] +from the [**Hospital Unit Name 153**] after admission for intoxication and concern for +pancreatitis given elevated amlyase and lipase. +. +In the ED, his initial vital signs were T 100.3, BP 106/45, HR +108, RR 18, O2sat 98% RA. He was found on exam to be very tender +to palpation of his abdomen with rebound and guarding. He was +pan-scanned given these findings. He was given 2L NS. He was +placed in a C collar for spine protection. He was given +levofloxacin 750mg IV x1 prior to imaging because he complained +of cough and had the low grade temp. He was given 5mg IV haldol +and written for 5mg PO valium but it is unclear if he received +this or not. +. +Currently, he is not answering very many questions. Obviously +intoxicated and sleeping. Denies pain. Could not tell me how +much alcohol he had today or what he drank. He usually admits to +vodka and listerine as his drinks of choice. +. + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +BP 105/67 HR 82 RR13 95% RA +Gen: somnolent man, disheaveled, NAD +HEENT: pupils 2-3mm, PERRLA, anicteric sclera, facial laceration +above R eyebrow, MM dry with lip cracking. Neck with JVD or LAD. +CV: RRR, no murmurs, rubs, gallops +Pulm: Clear to auscultation bilaterally +Abd: normoactive BS, soft, nondistended, tender to deep +palpation throughout. + guarding, tender with percussion. + +ecchymosis in RLQ +Ext: no edema, no rashes, 2+ pulses peripherally +Neuro: PERRLA. Responds to occasional questions, not following +commands. No tremors, no clonus. Opens eyes to verbal stimulus. +2+ patellar reflexes. + +Pertinent Results: +[**2181-12-12**] 08:30PM BLOOD WBC-3.7* RBC-3.34* Hgb-10.0* Hct-29.2* +MCV-88 MCH-30.0 MCHC-34.3 RDW-15.8* Plt Ct-316 +[**2181-12-12**] 08:30PM BLOOD Neuts-45.0* Lymphs-47.7* Monos-3.9 +Eos-2.2 Baso-1.1 +[**2181-12-12**] 08:30PM BLOOD Glucose-76 UreaN-11 Creat-1.0 Na-143 +K-4.1 Cl-106 HCO3-29 AnGap-12 +[**2181-12-12**] 08:30PM BLOOD ALT-39 AST-82* AlkPhos-69 Amylase-159* +TotBili-0.2 +[**2181-12-12**] 08:30PM BLOOD Lipase-80* +[**2181-12-12**] 08:30PM BLOOD cTropnT-<0.01 +[**2181-12-12**] 08:30PM BLOOD ASA-NEG Ethanol-304* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG +[**2181-12-12**] 08:41PM BLOOD Lactate-1.2 +. +[**2181-12-12**] CT Head: 1. No acute intracranial hemorrhage. 2. +Cerebellar atrophy. +. +[**2181-12-12**] CT C-Spine: No acute fracture or malalignment of the +cervical spine. Mild degenerative changes. +. +[**2181-12-12**] X-ray L elbow: No acute fracture or dislocation. Old +healed left humeral shaft fracture partially visualized. +. + +[**2181-12-12**] CXR: No acute cardiopulmonary process. +. +[**2181-12-12**] Abd/Pelvis CT: No CT evidence of pancreatitis or acute +intra-abdominal or pelvic findings. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. He had elevated amylase and lipase concerning for +pancreatitis. A CT of his abdomen was negative for any +abdominal pathology. Initially he was somnolent but on the day +after admission he became more arousable. He received +approximately 200mg of PO Valium over a 24 hour period for +alcohol withdrawal. He continued to complain of abdominal pain +but his abdomen was benign and CT did not show any pathology. +He was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. His LFTs were mildly elevated +consistent with alcoholic disease. He was given multivitamins, +thiamine and folate. His electrolytes were monitored; however +blood draws were difficult due to poor access. Social work and +addiction services were consulted. He was referred the [**Hospital1 **] +Stabilization Program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. An attempt was made to +transfer him to the floor and when he was told this, he held his +breath and O2 sats dropped to the 70s and he was tachycardic. +. +On [**2181-12-14**] he left the hospital against medical advice. He was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + +Medications on Admission: +none + +Discharge Medications: +pt left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Alcohol Withdrawal + +Discharge Condition: +fair + +Discharge Instructions: +Pt left AMA prior to receiving instructions. + +Followup Instructions: +Pt left AMA prior to receiving instructions. + + +",108,2181-12-12 22:29:00,2181-12-14 12:48:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,PANCREATITIS," +mr. [**known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. he had elevated amylase and lipase concerning for +pancreatitis. a ct of his abdomen was negative for any +abdominal pathology. initially he was somnolent but on the day +after admission he became more arousable. he received +approximately 200mg of po valium over a 24 hour period for +alcohol withdrawal. he continued to complain of abdominal pain +but his abdomen was benign and ct did not show any pathology. +he was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. his lfts were mildly elevated +consistent with alcoholic disease. he was given multivitamins, +thiamine and folate. his electrolytes were monitored; however +blood draws were difficult due to poor access. social work and +addiction services were consulted. he was referred the [**hospital1 **] +stabilization program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. an attempt was made to +transfer him to the floor and when he was told this, he held his +breath and o2 sats dropped to the 70s and he was tachycardic. +. +on [**2181-12-14**] he left the hospital against medical advice. he was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Alcoholic liver damage, unspecified; Lack of housing]" +5060,170299.0,24306,2182-04-01,24305,196749.0,2182-01-14,Discharge summary,"Admission Date: [**2182-1-4**] Discharge Date: [**2182-1-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 358**] +Chief Complaint: +Monitoring and treatment of EtOH withdrawal + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +This is a 37 year-old male with a history of alcoholism with +many admissions for intoxication, Hep B+C, polysubstance abuse, +and depression, who presents with intoxication. Pt reports that +he drank 1 liter of listerine today as well as a fifth of vodka +and then blackout. He was brought to the ED intoxicated but has +no recollection of how he got to the hospital. He complains of +pain at his left knee, but does not recall injuring it, and also +complains of chronic abdominal tenderness (but only when someone +presses on it). Denies nausea or vomiting. +. +In the ED, initial vitals were T 98.7, BP 123/87, HR 110, RR 16, +99% on RA. His BAL was 456. Serum tox was also positive for +benzos. Urine tox was negative. The plan was initially to +observe the patient overnight in the ED until he became sober. +However, around 7:30pm, the attending found the patient +tremulous, with HR in the 120-130s and complaining of withdrawal +symptoms. He was also having visual hallucinations of mice +running over his legs. Exam was only notable for some blood on +his pants over his left knee and a bump on his L forehead. Neuro +exam was non-focal. He remainted tachycardic with HR as high as +140s. He received a total of 15mg PO valium, 15mg IV valium, and +1mg IV ativan. Banana bag was started but PIV was not +functioning well. Admitted to the ICU for further monitoring. +. +On arrival to the [**Hospital Unit Name 153**], the patient is very anxious. He is no +longer experiencing visual hallucinations but reports that he is +delirious and does not know what is going on. He is adamant that +he is going to stop drinking this time and wants to go to a +detox facility-- apparently his best friend died one week ago +from drinking listerine. +. +ROS: He has been having frontal headaches for the past month +since being hit by an SUV one month ago. Has also had R-sided +chest pain at the site of impact from this MVC for the past +month. Has broken his nose several times and has difficulty +breathing from that. He also notes seeing spots in the periphery +of his vision recently. He complains of gait instability when +sober (less so when intoxicated) and also peripheral neuropathy +in his arms and legs. The patient denies any fevers, chills, +weight change, nausea, vomiting, abdominal pain, diarrhea, +constipation, melena, hematochezia, shortness of breath, +orthopnea, PND, lower extremity edema, cough, urinary frequency, +urgency, dysuria, lightheadedness, focal weakness, rash or skin +changes. + + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +Vitals: T: 98.7 BP: 138/106 HR: 132 RR: 17 O2Sat: 97% RA +GEN: Disheveled male, tremulous, anxious +HEENT: EOMI, PERRL, sclera anicteric, no nystagmus, no epistaxis +or rhinorrhea, MMM, OP Clear, poor dentition +NECK: No JVD, lymphadenopathy, trachea midline +COR: tachy, regular, no M/G/R, normal S1 S2, radial pulses +2 +PULM: Lungs CTAB, no W/R/R +ABD: Soft, diffusely tender to palpation, ND, +BS, no HSM, no +masses +EXT: No C/C/E, no palpable cords +MUSCULOSKELETAL: L knee swollen with 2 small healing lacerations +and echymossis over the patella, decreased range of motion (to +90 degrees), tender to palpation over the patella and medial +joint line +NEURO: A+O x 2 (person, year). CN II ?????? XII grossly intact. +Strength 5/5 in upper and lower extremities. Decreased sensation +grossly over lower extremities. Normal finger-to-nose. +SKIN: No jaundice, cyanosis, or gross dermatitis. No ecchymoses. + + + +Pertinent Results: +143 104 12 83 AGap=14 + +4.2 29 0.7 +ALT: 60 AP: 101 Tbili: 0.3 Alb: 4.6 +AST: 95 LDH: Dbili: TProt: 7.9 +[**Doctor First Name **]: Lip: 134 +Serum EtOH 456 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Comments: Positive Tricyclic Results Represent Potentially Toxic +Levels;Therapeutic Tricyclic Levels Will Typically Have Negative +Results + +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative + + 86 +5.8 12.3 313 + + 36.3 + N:40.2 L:53.0 M:3.8 E:1.6 Bas:1.4 +. + +FINDINGS: Lungs are clear without evidence lung nodules or +consolidations. +No pleural effusion. Cardiomediastinal silhouette is +unremarkable. Bone +structures are grossly normal. + +IMPRESSION: Normal examination without evidence of active or +inactive +tuberculosis. + +PPD positive with >20mm reaction + +Brief Hospital Course: +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of DTs/withdrawal seizures who +presents with intoxication followed by withdrawal. He received +30 mg Valium in the emergency room and was placed on a q1h CIWA +in the ICU. This was transitioned to a standing valium order per +his protocol on arrival to the floor. Social work was consulted. +MVI/thiamine/folate were given. He was monitored on telemetry. +. +His lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis C, in addition to +alcoholic hepatitis. He had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. This +improved and he was tolerating pos. +. +He noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +He was started on Klonopin for anxiety, similar to previous +outpatient dosing. He had a PPD placed, which was positive at +>20 mm, and a CXR was performed which was negative. + +Unfortunately, on the day of anticipated discharge to [**Hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (AMA, although he left without +risk/benefit). + +Medications on Admission: +none +chronically on klonopin, but it is frequently stolen on the +street. + +Discharge Medications: +none, AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +alcohol withdrawal/dependence +anxiety + + +Discharge Condition: +ambulating, no longer in withdrawal + + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + + +",77,2182-01-04 17:40:00,2182-01-14 10:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +37 year-old male with a history of alcoholism with multiple +admissions for detox and history of dts/withdrawal seizures who +presents with intoxication followed by withdrawal. he received +30 mg valium in the emergency room and was placed on a q1h ciwa +in the icu. this was transitioned to a standing valium order per +his protocol on arrival to the floor. social work was consulted. +mvi/thiamine/folate were given. he was monitored on telemetry. +. +his lipase and transaminases were elevated during his admission, +consistent with his chronic hepatitis c, in addition to +alcoholic hepatitis. he had abdominal pain which was the same as +on prior admissions and was likely related to alcoholic +pancreatitis or gastritis, but was resolved on discharge. this +improved and he was tolerating pos. +. +he noted knee pain as well, and an x-ray was performed which did +not show a fracture. +. +he was started on klonopin for anxiety, similar to previous +outpatient dosing. he had a ppd placed, which was positive at +>20 mm, and a cxr was performed which was negative. + +unfortunately, on the day of anticipated discharge to [**hospital1 **] +for inpatient alcohol rehabilitation, he left the floor +unwitnessed and did not return (ama, although he left without +risk/benefit). + + ","PRIMARY: [Alcohol withdrawal delirium] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic pancreatitis; Chronic hepatitis C without mention of hepatic coma; Acute alcoholic hepatitis; Acute alcoholic intoxication in alcoholism, continuous; Pain in joint, lower leg; Lack of housing; Anxiety state, unspecified; Other, mixed, or unspecified drug abuse, unspecified; ]" +5060,196749.0,24305,2182-01-14,24300,194191.0,2181-08-21,Discharge summary,"Admission Date: [**2181-8-20**] Discharge Date: [**2181-8-21**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2485**] +Chief Complaint: +etoh w/d + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +36 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions returns with alcohol intoxication. He +reports that he has been drinking daily since being released +from prison on [**7-10**]. He drinks enough vodka or listerine so +that he blacks out daily. He believes he was brought in by EMS +or a local after he was found intoxicated. Per ED reports, he +was BIBA after being found down. + +He was most recently admitted for EtOh withdrawal from [**2-24**] - +[**3-5**] and left AMA after his valium dose was tapered. He returned +on [**7-4**] with a fall but was discharged from the ED after a +negative head CT. +. +ED: VS on arrival 98.5 114 128/62 16 97% RA. Tox was negative +for cocaine, amphetamines. Serum tox was positive for etoh 448 +and benzos. Had anion gap of 18 but VBG of 7.49/33/58 and +lactate of 3.1. We was given 60-70 IV valium for withdrawal sx +of agitation, hypertension, and tachycardia. Also received 3L +IVF. +. +Currently, the patient reports having chest pain x1wk. he +thinks he was punched in the chest and has since had +intermittently dull/sharp nonradiating substernal chest pain. +Now it is [**9-16**] and sharp. It is not exertional nor assoc with +SOB or diaphoresis/n/v. Worse w palpation. Also reports +falling and hitting right forehead 10d ago. Has had no fevers +or residual HA since that time. +. +ROS otherwise pos for URI-like sx. no diarrhea. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures - once sent under +section 35 to prison due to concern that he was a severe threat +to himself with his drinking. required intubation in the past. +- has been seen recently by psychiatry in the past to evaluate +for possible section 35. + +Social History: +Drinks regularly, prefers listerine and vodka. Has been +drinking heavily since release from prison on [**8-9**]. +Homeless, lives on streets. Denies IVDU for >10yrs. Denies +cigs for>10 yrs. Denies SI or HI + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 99.8 110 96% RA RR12 133/111 +gen: agitated but redirectable. +Neuro: aao to person, place, time, situation. +- cn ii-xii intact +- motor [**6-11**] bilat upper/lower +- slightly tremulous upper ex +- [**Last Name (un) 36**] to light touch +- gait wide based and unsteady +- f-n intact bilat +- h-s impaired bilat +heent: old scar on right forehead. mm dry, jvp flat +cards: tachy, reg, no murmurs +resp: ctab +abd: BS+ NT ND soft, no rebound, no stigmata of liver dz +Ext: no edema. good pulses + +Pertinent Results: +EKG: Sinus tachy, nl axis, nl intervals, no acute st-t changes. +. +Labs: +VBG: 7.49/33/58 +Lactate 3.1 +. +142 102 10 +----------------< 87 +4.1 22 0.9 +Ca: 9.4 Mg: 2.0 P: 2.9 +Serum EtOH 448 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +. +WBC: 9.5 +HCT: 35.7 - at baseline +PLT: 208 +N:64.2 L:30.8 M:3.5 E:1.1 Bas:0.5 +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Repeat chemistry: +140 108 8 +-------------< 73 +3.3 20 0.7 +Ca: 8.0 Mg: 1.6 P: 1.9 +repeat lactate 3.1 + +Brief Hospital Course: +36M with ETOH dependence and frequent admissions for EtOH +intoxication presents with EtOH withdrawal. ICU-east course by +problem: +. +# Alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. Has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of DTs and w/d seizures, we treated +aggressively with valium in ICU. He received either 60-70 IV +valium in the ED. On arrival to the ICU, he was written for +valium 20mg PO q15m prn CIWA>10 and he received it almost as +frequently as written. He became less agitated after approx +80-100mg (in addition to the IV given in the ED) and then the +CIWA scale was spread out to 20mg PO prn q1h. He tolerated +this transition well. +- He received multivit, folate, thiamine in IVF then PO +- social work was consulted the morning after admission when +patient was demanding to leave. He felt he had enough valium +and actually refused another dose. We explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. He expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. He signed out +AMA with plans to seek outpatient treatment. +. +# Psych: No SI. We had plans to contact psychiatry morning +after admission particularly given his high valium need. +However, he expressed interest in leaving and we felt he had +capacity to make this decision. Social wk was involved but +psychiatry was not consulted. +. +# chest pain: EKG without ischemic changes. CP was reproducible +on palpation. Suspected MSK pain. He received one dose of +morphine for cp. We then treated with toradol, motrin, and +tylenol. We would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. His pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. Lactic acidosis not likely +given the alkalosis seen on VBG. Consider dehydration vs poor +quality sample. Infection less likely given no fever or +hypotension or any localizing signs of infection. Repeat +lactate remained 3.1. Etiology unclear and workup hindered by +patient leaving AMA. +. +# Anion gap: AG 18 in the ED with a normal HCO3 and alkalosis on +VBG. ASA negative as were other toxins. Difficult to interpret +but wonder if slightly increased AG is from the elevated +lactate. Repeat chemistries showed normal anion gap. +. +#Anemia - normocytic anemia, Hct at baseline +. +# PPx: Heparin sc tid, PPI given etoh abuse, bowel reg +. +# FEN: Regular diet, replete lytes prn, banana bag then IVF +. +# Access: PIV x1 +. +# Code: FULL +. +# Communication: Patient +. +# Dispo: Patient left AMA. + + +Medications on Admission: +none + +Discharge Medications: +none + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH Intoxication/Withdrawal + + +Discharge Condition: +fair + + +Discharge Instructions: +You were admitted to the hospital because you were found +intoxicated by EMS. You were admitted to the ICU and treated +with Valium for withdrawal. You were advised to stay in the +hospital for continued care and treatment of withdrawal however +you decided against medical advice that you no longer wished to +receive care. You spoke with the social worker before you left +the hospital and were advised to return to [**Street Address(1) 5904**] Inn +to speak with your outreach worker there. + +You signed out against medical advise. + +Followup Instructions: +Please speak with the Outreach worker [**Street Address(1) 29735**] Inn. + +Please return to the hospital should you have any concerning +symptoms including difficulty breathing, falls or injuries +requiring medical attention, concerning withdrawal symptoms. + + + +",146,2181-08-20 20:26:00,2181-08-21 11:10:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +36m with etoh dependence and frequent admissions for etoh +intoxication presents with etoh withdrawal. icu-east course by +problem: +. +# alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of dts and w/d seizures, we treated +aggressively with valium in icu. he received either 60-70 iv +valium in the ed. on arrival to the icu, he was written for +valium 20mg po q15m prn ciwa>10 and he received it almost as +frequently as written. he became less agitated after approx +80-100mg (in addition to the iv given in the ed) and then the +ciwa scale was spread out to 20mg po prn q1h. he tolerated +this transition well. +- he received multivit, folate, thiamine in ivf then po +- social work was consulted the morning after admission when +patient was demanding to leave. he felt he had enough valium +and actually refused another dose. we explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. he expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. he signed out +ama with plans to seek outpatient treatment. +. +# psych: no si. we had plans to contact psychiatry morning +after admission particularly given his high valium need. +however, he expressed interest in leaving and we felt he had +capacity to make this decision. social wk was involved but +psychiatry was not consulted. +. +# chest pain: ekg without ischemic changes. cp was reproducible +on palpation. suspected msk pain. he received one dose of +morphine for cp. we then treated with toradol, motrin, and +tylenol. we would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. his pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. lactic acidosis not likely +given the alkalosis seen on vbg. consider dehydration vs poor +quality sample. infection less likely given no fever or +hypotension or any localizing signs of infection. repeat +lactate remained 3.1. etiology unclear and workup hindered by +patient leaving ama. +. +# anion gap: ag 18 in the ed with a normal hco3 and alkalosis on +vbg. asa negative as were other toxins. difficult to interpret +but wonder if slightly increased ag is from the elevated +lactate. repeat chemistries showed normal anion gap. +. +#anemia - normocytic anemia, hct at baseline +. +# ppx: heparin sc tid, ppi given etoh abuse, bowel reg +. +# fen: regular diet, replete lytes prn, banana bag then ivf +. +# access: piv x1 +. +# code: full +. +# communication: patient +. +# dispo: patient left ama. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Alkalosis; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Acidosis; Chronic hepatitis C without mention of hepatic coma; Cocaine abuse, unspecified; Lack of housing; Anemia, unspecified; Other chest pain]" +5060,196749.0,24305,2182-01-14,24301,153063.0,2181-10-24,Discharge summary,"Admission Date: [**2181-10-23**] Discharge Date: [**2181-10-24**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5893**] +Chief Complaint: +CC:[**CC Contact Info 61604**] +Major Surgical or Invasive Procedure: +none + +History of Present Illness: + +HPI: 37YO man with long hx of alcohol abuse, with frequent ED +visits/hospitalizations for same was brought to the ED today +after being found by EMS sleeping on street. He reports drinking +[**2-8**] pints of vodka daily. He eats very little. He also drinks +listerine each night. He reports frequent falls (recent scalp +lac w/ staples; abrasion over face). His ETOH level was 434 at +10:00 AM. He was given Ativan 2 mg at 6:30 in the ED for CIWA +=13; then given Ativan 2 mg at 6:30pm for CIWA = 23. He was +admitted to the floor for EtOH withdrawal. +. +On arrival to the floor, the patient was given Valium 10 mg PO +and 10 mg IV over 40 minutes without improvement in his CIWA. +He is transferred to the ICU for further management. +. +Of note, previous admission in [**Month (only) 205**] for ETOH withdrawal pt +required 20mg PO valium q15min, then left AMA. +. +Pt not cooperative for further ROS. +. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Currently reports drinking ""at least"" a lint of vodka each +morning and listerine each evening. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration +for possession, estranged from family, never married, no +children, homeless + +Family History: +Possible OCD in his father. + +Physical Exam: +Vitals: 99.3, 110/64, 115, 18, 99% RA +GEN: diaphoretic, sitting in bed, anxious +HEENT:hematoma on R occipital area where staples removed last +week. scabb on bridge of nose and R temple. PERRLA 5mm->2mm, +EOMI, throat non-erythematous, poor dentition, MMM +Lungs: clear +CV: tachy, rrr +Abd: + bs soft, limited exam, no focal tenderness +ext: + tremor, no c/c/e + + +Pertinent Results: +Labs: +. +143 /103 / 11 /140 Ca: 8.8 Mg: 2.1 P: 3.3 +-------------- +3.9 /31 / 0.8 + +. +4.7 / 13.0 / 315 N:35.4 L:50.6 M:4.4 E:7.8 Bas:1.8 + ------- + 39.6 +. +Serum EtOH 434, Serum Benzo Pos, +Serum ASA, Acetmnphn, Barb, Tricyc Negative +Urine Benzos Pos +Urine Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Imaging: None + + +Brief Hospital Course: +In summary, Mr. [**Known lastname 24927**] is a 37 yo male with history of ETOH +abuse presents with acute ETOH intoxication. +. +ETOH abuse. Patient has a long history of alcohol abuse, with +innumerable ED visits and hospitalizations for same. Patient +was initially on diazepam CIWA scale. Within twelve hours of +admission, patient was requesting to leave AMA. He was +evaluated by psychiatry who felt he had competence to leave AMA. + He was not a candidate for section 35. Risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + +Medications on Admission: +None + +Discharge Medications: +None. Patient left AMA. + +Discharge Disposition: +Home + +Facility: +AMA + +Discharge Diagnosis: +Alcohol abuse. + +Discharge Condition: +AMA + +Discharge Instructions: +AMA + +Followup Instructions: +AMA + + +",82,2181-10-23 18:54:00,2181-10-24 15:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +in summary, mr. [**known lastname 24927**] is a 37 yo male with history of etoh +abuse presents with acute etoh intoxication. +. +etoh abuse. patient has a long history of alcohol abuse, with +innumerable ed visits and hospitalizations for same. patient +was initially on diazepam ciwa scale. within twelve hours of +admission, patient was requesting to leave ama. he was +evaluated by psychiatry who felt he had competence to leave ama. + he was not a candidate for section 35. risks of leaving +hospital against medical advice was discussed with the patient, +but he decided to leave. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Alcoholic polyneuropathy; Lack of housing]" +5060,196749.0,24305,2182-01-14,24302,184857.0,2181-11-20,Discharge summary,"Admission Date: [**2181-11-18**] Discharge Date: [**2181-11-20**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +ETOH Withdrawal + +Major Surgical or Invasive Procedure: +PICC placement ([**2181-11-19**]) + +History of Present Illness: +37 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions and ED evals returns with alcohol +intoxication and withdrawal. Presented to ED s/p unwitnessed +fall while intoxicated. Came in c/o L elbow and R hand pain. +Also with left supraorbital laceration that was repaired in the +ED. He reports currently drinking 1 bottle of Vodka and large +bottle of mouthwash daily. He has a hx of withdrawal seizures as +well as Section 35/Section 12 for ETOH abuse. +. +In the ED, initial VS: T96.6 HR 80 BP 108/73 RR16 100RA. He was +monitored overnight, but noted to be progressively more +tremulous and tachycardic. Also reported hallucinations. +Initially was threatening to leave AMA, but agreed to stay for +further treatment. Team unable to get PIVs so femoral line +placed for access. He received 50mg PO valium and 2mg of Ativan +IM since [**85**]:40 AM. +. +He was most recently admitted for EtOh withdrawal on [**11-9**] but +left AMA. He returned to the ED on [**11-13**] for intoxication and +was noted to have elevated amylase, lipase concerning for acute +pancreatitis. Again, pt signed out AMA. +. +On arrival to [**Hospital Unit Name 153**], patient was tremulous, complaining of pain +all over and felt like his ""skin was crawling."" Also reported +chronic abdominal pain over the last several months that he +attributed to excessive intake of listerine. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: Afebrile, BP 146/60, HR 114 RR 16 98%RA +GEN: Anxious, cooperative. +Neuro: AAO to person, place, time, situation. +- CN ii-xii intact +- motor [**6-11**] bilat upper/lower +- tremulous bilateral upper ext +- [**Last Name (un) 36**] to light touch intact +- toes downgoing bilaterally +- gait: not assessed as patient unsteady +HEENT: 1.5cm laceration with sutures and associated ecchymosis +and swelling of L eyebrow. Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non distended; mild tenderness throughout, hypoactive +BS +Ext: R femoral line C/D/I; no edema. good pulses +SKIN: No rashes + + +Pertinent Results: +[**2181-11-20**] 05:35AM BLOOD WBC-5.1 RBC-4.03* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.6 MCHC-34.1 RDW-14.8 Plt Ct-190 +[**2181-11-19**] 03:41AM BLOOD WBC-4.3 RBC-3.85* Hgb-11.6* Hct-33.3* +MCV-87 MCH-30.2 MCHC-34.8 RDW-15.5 Plt Ct-195 +[**2181-11-18**] 02:31PM BLOOD WBC-6.1 RBC-4.43* Hgb-13.2* Hct-37.8* +MCV-85 MCH-29.9 MCHC-35.0 RDW-16.0* Plt Ct-272# +[**2181-11-18**] 02:31PM BLOOD Neuts-32.6* Lymphs-57.1* Monos-6.0 +Eos-3.2 Baso-1.2 +[**2181-11-20**] 05:35AM BLOOD PT-12.0 PTT-33.4 INR(PT)-1.0 +[**2181-11-20**] 05:35AM BLOOD Glucose-93 UreaN-8 Creat-0.6 Na-136 K-3.8 +Cl-104 HCO3-24 AnGap-12 +[**2181-11-20**] 05:35AM BLOOD ALT-44* AST-72* LD(LDH)-286* +[**2181-11-20**] 05:35AM BLOOD Calcium-8.4 Phos-3.4 Mg-1.9 +[**2181-11-18**] 02:31PM BLOOD ASA-NEG Ethanol-137* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +36M with EtOH dependence and frequent admissions for EtOH +intoxication presents s/p fall with EtOH withdrawal. + +1. Alcohol withdrawal: No hypertension or tachycardia this +morning. Slightly agitated and with slight upper extremity +tremor. Has history of hx of DTs and w/d seizures. Patient was +treated with CIWA scale per prior admissions. On hospital day +3, patient signed out AMA. + +2. Fall: Patient with unwitnessed fall. Radiographs negative +for fracture. + +3. Abdominal pain: [**Month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of LFTs. + +4. Alcoholic liver disease: AST/ALT improving. No stigmata of +liver disease by physical exam. [**Doctor First Name **]/lipase normal. Also has +history of hepatitis B/C. + +5. Anemia: Normocytic anemia, at baseline. + +6. PPx: Patient treated with heparin SQ for dvt prophylaxis. + +7. Access: Patient with femoral CVL placed in ED. PICC placed +during admission, which was removed when patient signed out AMA. + +8. Dispo: Patient signed out AMA. + +Medications on Admission: +None + +Discharge Medications: +1. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +EtOH withdrawal + + +Discharge Condition: +Patient leaving against medical advice. + + +Discharge Instructions: +You were admitted for alcohol withdrawal and received +benzodiazepines to manage your withdrawal. We recommended +transfer to the regular medical floor from the ICU for continued +management of your withdrawal symptoms, but you have decided to +leave against our medical advice. + +Followup Instructions: +Please follow up with your primary care doctor within the next +few days. You should also seek care for substance abuse. + + + +Completed by:[**2181-11-20**]",55,2181-11-18 06:42:00,2181-11-20 12:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALTERED MENTAL STATUS," +36m with etoh dependence and frequent admissions for etoh +intoxication presents s/p fall with etoh withdrawal. + +1. alcohol withdrawal: no hypertension or tachycardia this +morning. slightly agitated and with slight upper extremity +tremor. has history of hx of dts and w/d seizures. patient was +treated with ciwa scale per prior admissions. on hospital day +3, patient signed out ama. + +2. fall: patient with unwitnessed fall. radiographs negative +for fracture. + +3. abdominal pain: [**month (only) 116**] be secondary to alcoholic hepatitis +though minimal elevation of lfts. + +4. alcoholic liver disease: ast/alt improving. no stigmata of +liver disease by physical exam. [**doctor first name **]/lipase normal. also has +history of hepatitis b/c. + +5. anemia: normocytic anemia, at baseline. + +6. ppx: patient treated with heparin sq for dvt prophylaxis. + +7. access: patient with femoral cvl placed in ed. picc placed +during admission, which was removed when patient signed out ama. + +8. dispo: patient signed out ama. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Open wound of forehead, without mention of complication; Unspecified fall; Chronic hepatitis C without mention of hepatic coma; Lack of housing; Anemia, unspecified; Acute alcoholic hepatitis; Alcoholic gastritis, without mention of hemorrhage; Hypovolemia]" +5060,196749.0,24305,2182-01-14,24303,197750.0,2181-12-11,Discharge summary,"Admission Date: [**2181-12-7**] Discharge Date: [**2181-12-11**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 8487**] +Chief Complaint: +ETOH Withdrawal, Chest, Abdominal, Arm and Hand Pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +37yoM with hx of polysubstance abuse, frequent ICU admissions +and ED evals returns with alcohol intoxication and withdrawal. +Pt reports currently using ETOH, and presenting for pain from a +reported trauma approx 4 days ago at which time the patient +reports being hit by a SUV. He states he signed out AMA from the +[**Hospital1 3278**] ICU after this accident. Pt with a hx of withdrawal +seizures as well as Section 35/Section 12 for ETOH abuse. The +patient reports being acutely intoxicated currently, and most +recently, drinking Listerine this am. Today the patient was +found lying next to [**Company 2486**] where EMS was called and we +has brought to the ED. Since leaving [**Hospital1 3278**] he has spent the past +few days at [**Location (un) 7073**] Station, drinking Vodka during the day and +Listerine at night ""to prevent seizures"". He believes his last +seizure occurred three weeks ago. He notes pain all over his +body - esp in his hands, chest, abdomen and legs. +. +In the ED, initial VS 98.3 120/88 116 16 100%2L: In the E.D. he +received Morphine 6mg, Valium 50mg, Gabapentin 600mg, Toradol +30mg, 1 banana bag and 2 additional L of NS. He was monitored, +but noted to be progressively more tremulous, tachycardic and +reporting visual hallucinations. +. +Of note the pt has had recent admissions for EtOh withdrawal on +[**11-9**] but left AMA. He returned to the ED on [**11-13**] for +intoxication and was noted to have elevated amylase, lipase +concerning for acute pancreatitis. Again, pt signed out AMA. The +pt was admitted on [**11-18**], again for acute EtOH withdrwal, and +signed out AMA on [**11-20**]. +. +On arrival to [**Hospital Unit Name 153**]: Pt tremulous, anxious, tachy to 110s, with +some visual hallucinations, however not hypertensive or febrile. +Pt denies fever, + chills, headache. Admits to chronic abdominal +pain of [**8-14**] months duration. Pt also admits to chest pain of one +weeks duration since being hit by a car. Pt also noted recent +episodes of epistaxis, although none within the past few days. +. + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C (Diagnosed around [**2163**], Never treated) +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Homeless, lives on streets. Denies IVDU for >10yrs. Denies cigs +for>10 yrs. Denies SI or HI. He has a history of +polysubstance abuse: EtOH, heroin, IVDU, benzo, h/o alcohol +withdrawal seizures and DT's, h/o section 35. h/o incarceration + +for ETOH, estranged from family, never married, no children, +homeless. Last worked 17 years ago as a grocery shelf stocker. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 98.7 113/77 89 98 3LNC +GEN: Anxious, cooperative. Alert to date, name but not to +location +HEENT: PERRLA Dry MM, jvp flat; Poor dentition +CV: Tachycardic, reg, no murmurs +RESP: CTABL, no w/r/r +ABD: Soft/non-distended; mild tenderness throughout, hypoactive +BS +Ext: 1+ Bilateral upper extremity edema. good pulses +SKIN: No rashes +Neuro: AOx2, (not location), CN II-XII intact, Motor [**6-11**] bilat, +Tremulous bilateral upper ext + + +Pertinent Results: +Admission labs +[**2181-12-7**] 05:35PM BLOOD WBC-3.5* RBC-3.97* Hgb-11.8* Hct-34.7* +MCV-87 MCH-29.7 MCHC-34.0 RDW-15.4 Plt Ct-308# +[**2181-12-7**] 05:35PM BLOOD Neuts-33.4* Bands-0 Lymphs-57.1* +Monos-5.0 Eos-3.2 Baso-1.3 +[**2181-12-7**] 05:35PM BLOOD PT-13.3 PTT-29.8 INR(PT)-1.1 +[**2181-12-7**] 05:35PM BLOOD Glucose-198* UreaN-7 Creat-0.8 Na-143 +K-3.8 Cl-102 HCO3-25 AnGap-20 +[**2181-12-7**] 05:35PM BLOOD ALT-52* AST-101* CK(CPK)-359* AlkPhos-83 +[**2181-12-7**] 05:35PM BLOOD Lipase-135* +[**2181-12-7**] 05:35PM BLOOD Albumin-4.3 +[**2181-12-9**] 04:24AM BLOOD TSH-3.1 +[**2181-12-7**] 05:35PM BLOOD ASA-NEG Ethanol-396* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG + +[**2181-12-7**]: CXR IMPRESSION: No acute cardiopulmonary abnormality. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] is a 37M with ETOH dependence and frequent +admissions for EtOH intoxication who presents with EtOH +withdrawal and global pain. +. +# EtoH Withdrawal:On admission, the pt was A0x2. Throughout his +ICU stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. CIWAs 16-29. However, it +is also notable that he knows how to manipulate the CIWA and +would frequently do so in order to get increasing amounts of +benzodiazepines. On [**12-11**], his CIWA was discontinued and he was +told he would be transferred to the floor at which point he +signout AMA. While here, he was given thiamine, MVI, folate and +PRN electrolytes. +. +# Abdominal and Chest pain: DDx includes recent trauma (although +nothing apparent on exam), acute EtOh hepatitis, pancreatitis, +though minimal elevation of LFTs. Less likely cardiac given +reproducible nature, and unchanged EKG. No fever or leukocytosis +at this time. Lipase slightly increased from [**11-18**] (135 from +56). No evidence of ascites on recent Abd U/S. Troponins were +trended. He was given oxycodone 5-10mg Q 4hrs PRN. +. +# Alcoholic liver disease: AST/ALT elevated in 2:1 ratio, this +is his baseline. No stigmata of liver disease by physical exam. +Lipase 135 normal. INR 1.1. No scopes in [**Hospital1 **] records. LFTs and +coags were monitored. +. +# Anemia - Iron deficiency anemia baseline per [**11-9**] labs with +Ferritin of 11. Hct drop from 34 to 28 in setting of 3L IVF upon +admission. No active signs of bleeding, likely diluational. Hct +was monitored, pt was given po iron, folate and thiamine. + + +Medications on Admission: +None + +Discharge Medications: +Pt was not given medications nor discharge instructions as he +left AMA on the morning of [**2181-12-11**]. + +Discharge Disposition: +Home + +Discharge Diagnosis: +. + +Discharge Condition: +. + +Discharge Instructions: +. + +Followup Instructions: +. + + +Completed by:[**2182-1-10**]",34,2181-12-08 19:58:00,2181-12-11 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH INTOXICATION," +mr. [**known lastname 24927**] is a 37m with etoh dependence and frequent +admissions for etoh intoxication who presents with etoh +withdrawal and global pain. +. +# etoh withdrawal:on admission, the pt was a0x2. throughout his +icu stay, he had signs of withdrawal with, tachycardia, and +tremors of upper extremity bilateral. ciwas 16-29. however, it +is also notable that he knows how to manipulate the ciwa and +would frequently do so in order to get increasing amounts of +benzodiazepines. on [**12-11**], his ciwa was discontinued and he was +told he would be transferred to the floor at which point he +signout ama. while here, he was given thiamine, mvi, folate and +prn electrolytes. +. +# abdominal and chest pain: ddx includes recent trauma (although +nothing apparent on exam), acute etoh hepatitis, pancreatitis, +though minimal elevation of lfts. less likely cardiac given +reproducible nature, and unchanged ekg. no fever or leukocytosis +at this time. lipase slightly increased from [**11-18**] (135 from +56). no evidence of ascites on recent abd u/s. troponins were +trended. he was given oxycodone 5-10mg q 4hrs prn. +. +# alcoholic liver disease: ast/alt elevated in 2:1 ratio, this +is his baseline. no stigmata of liver disease by physical exam. +lipase 135 normal. inr 1.1. no scopes in [**hospital1 **] records. lfts and +coags were monitored. +. +# anemia - iron deficiency anemia baseline per [**11-9**] labs with +ferritin of 11. hct drop from 34 to 28 in setting of 3l ivf upon +admission. no active signs of bleeding, likely diluational. hct +was monitored, pt was given po iron, folate and thiamine. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Lack of housing]" +5060,196749.0,24305,2182-01-14,24304,135773.0,2181-12-14,Discharge summary,"Admission Date: [**2181-12-12**] Discharge Date: [**2181-12-14**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +abdominal pain, alcohol withdrawal + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +HPI: 37 yo M with PMH of alcohol abuse with many admissions for +intoxication, hepatitis B and C who was brought in by the police +after being found intoxicated. He originally did not complain of +any pain or other problems. Of note, he was left AMA [**2181-12-11**] +from the [**Hospital Unit Name 153**] after admission for intoxication and concern for +pancreatitis given elevated amlyase and lipase. +. +In the ED, his initial vital signs were T 100.3, BP 106/45, HR +108, RR 18, O2sat 98% RA. He was found on exam to be very tender +to palpation of his abdomen with rebound and guarding. He was +pan-scanned given these findings. He was given 2L NS. He was +placed in a C collar for spine protection. He was given +levofloxacin 750mg IV x1 prior to imaging because he complained +of cough and had the low grade temp. He was given 5mg IV haldol +and written for 5mg PO valium but it is unclear if he received +this or not. +. +Currently, he is not answering very many questions. Obviously +intoxicated and sleeping. Denies pain. Could not tell me how +much alcohol he had today or what he drank. He usually admits to +vodka and listerine as his drinks of choice. +. + +Past Medical History: +polysubstance abuse with alcohol, heroin, IVDU, benzo +Hep C +Hep B +OCD and anxiety +Depression +seizures from alcohol withdrawal +compartment syndrome of RLE in [**2171**] +chronic bilateral hand swelling + +Social History: +Homeless. Denies IVDU recently. Denies tobacco recently. Does +have a history of both. + +Family History: +father with depression and alcoholism. Mother had diabetes. + +Physical Exam: +BP 105/67 HR 82 RR13 95% RA +Gen: somnolent man, disheaveled, NAD +HEENT: pupils 2-3mm, PERRLA, anicteric sclera, facial laceration +above R eyebrow, MM dry with lip cracking. Neck with JVD or LAD. +CV: RRR, no murmurs, rubs, gallops +Pulm: Clear to auscultation bilaterally +Abd: normoactive BS, soft, nondistended, tender to deep +palpation throughout. + guarding, tender with percussion. + +ecchymosis in RLQ +Ext: no edema, no rashes, 2+ pulses peripherally +Neuro: PERRLA. Responds to occasional questions, not following +commands. No tremors, no clonus. Opens eyes to verbal stimulus. +2+ patellar reflexes. + +Pertinent Results: +[**2181-12-12**] 08:30PM BLOOD WBC-3.7* RBC-3.34* Hgb-10.0* Hct-29.2* +MCV-88 MCH-30.0 MCHC-34.3 RDW-15.8* Plt Ct-316 +[**2181-12-12**] 08:30PM BLOOD Neuts-45.0* Lymphs-47.7* Monos-3.9 +Eos-2.2 Baso-1.1 +[**2181-12-12**] 08:30PM BLOOD Glucose-76 UreaN-11 Creat-1.0 Na-143 +K-4.1 Cl-106 HCO3-29 AnGap-12 +[**2181-12-12**] 08:30PM BLOOD ALT-39 AST-82* AlkPhos-69 Amylase-159* +TotBili-0.2 +[**2181-12-12**] 08:30PM BLOOD Lipase-80* +[**2181-12-12**] 08:30PM BLOOD cTropnT-<0.01 +[**2181-12-12**] 08:30PM BLOOD ASA-NEG Ethanol-304* Acetmnp-NEG +Bnzodzp-POS Barbitr-NEG Tricycl-NEG +[**2181-12-12**] 08:41PM BLOOD Lactate-1.2 +. +[**2181-12-12**] CT Head: 1. No acute intracranial hemorrhage. 2. +Cerebellar atrophy. +. +[**2181-12-12**] CT C-Spine: No acute fracture or malalignment of the +cervical spine. Mild degenerative changes. +. +[**2181-12-12**] X-ray L elbow: No acute fracture or dislocation. Old +healed left humeral shaft fracture partially visualized. +. + +[**2181-12-12**] CXR: No acute cardiopulmonary process. +. +[**2181-12-12**] Abd/Pelvis CT: No CT evidence of pancreatitis or acute +intra-abdominal or pelvic findings. + +Brief Hospital Course: +Mr. [**Known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. He had elevated amylase and lipase concerning for +pancreatitis. A CT of his abdomen was negative for any +abdominal pathology. Initially he was somnolent but on the day +after admission he became more arousable. He received +approximately 200mg of PO Valium over a 24 hour period for +alcohol withdrawal. He continued to complain of abdominal pain +but his abdomen was benign and CT did not show any pathology. +He was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. His LFTs were mildly elevated +consistent with alcoholic disease. He was given multivitamins, +thiamine and folate. His electrolytes were monitored; however +blood draws were difficult due to poor access. Social work and +addiction services were consulted. He was referred the [**Hospital1 **] +Stabilization Program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. An attempt was made to +transfer him to the floor and when he was told this, he held his +breath and O2 sats dropped to the 70s and he was tachycardic. +. +On [**2181-12-14**] he left the hospital against medical advice. He was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + +Medications on Admission: +none + +Discharge Medications: +pt left AMA + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Alcohol Withdrawal + +Discharge Condition: +fair + +Discharge Instructions: +Pt left AMA prior to receiving instructions. + +Followup Instructions: +Pt left AMA prior to receiving instructions. + + +",31,2181-12-12 22:29:00,2181-12-14 12:48:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,PANCREATITIS," +mr. [**known lastname 24927**] was admitted with alcohol intoxication and abdominal +pain. he had elevated amylase and lipase concerning for +pancreatitis. a ct of his abdomen was negative for any +abdominal pathology. initially he was somnolent but on the day +after admission he became more arousable. he received +approximately 200mg of po valium over a 24 hour period for +alcohol withdrawal. he continued to complain of abdominal pain +but his abdomen was benign and ct did not show any pathology. +he was not given narcotics due to concerns for interactions with +benzodiazepines and alcohol. his lfts were mildly elevated +consistent with alcoholic disease. he was given multivitamins, +thiamine and folate. his electrolytes were monitored; however +blood draws were difficult due to poor access. social work and +addiction services were consulted. he was referred the [**hospital1 **] +stabilization program who was in the process of accepting him +possibly friday [**12-14**] or monday [**12-17**]. an attempt was made to +transfer him to the floor and when he was told this, he held his +breath and o2 sats dropped to the 70s and he was tachycardic. +. +on [**2181-12-14**] he left the hospital against medical advice. he was +informed of the risks of alcohol withdrawal, hallucinations, +seizures, delerium, and death. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Chronic hepatitis C without mention of hepatic coma; Iron deficiency anemia, unspecified; Alcoholic liver damage, unspecified; Lack of housing]" +5060,153063.0,24301,2181-10-24,24300,194191.0,2181-08-21,Discharge summary,"Admission Date: [**2181-8-20**] Discharge Date: [**2181-8-21**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2485**] +Chief Complaint: +etoh w/d + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +36 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions returns with alcohol intoxication. He +reports that he has been drinking daily since being released +from prison on [**7-10**]. He drinks enough vodka or listerine so +that he blacks out daily. He believes he was brought in by EMS +or a local after he was found intoxicated. Per ED reports, he +was BIBA after being found down. + +He was most recently admitted for EtOh withdrawal from [**2-24**] - +[**3-5**] and left AMA after his valium dose was tapered. He returned +on [**7-4**] with a fall but was discharged from the ED after a +negative head CT. +. +ED: VS on arrival 98.5 114 128/62 16 97% RA. Tox was negative +for cocaine, amphetamines. Serum tox was positive for etoh 448 +and benzos. Had anion gap of 18 but VBG of 7.49/33/58 and +lactate of 3.1. We was given 60-70 IV valium for withdrawal sx +of agitation, hypertension, and tachycardia. Also received 3L +IVF. +. +Currently, the patient reports having chest pain x1wk. he +thinks he was punched in the chest and has since had +intermittently dull/sharp nonradiating substernal chest pain. +Now it is [**9-16**] and sharp. It is not exertional nor assoc with +SOB or diaphoresis/n/v. Worse w palpation. Also reports +falling and hitting right forehead 10d ago. Has had no fevers +or residual HA since that time. +. +ROS otherwise pos for URI-like sx. no diarrhea. + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures - once sent under +section 35 to prison due to concern that he was a severe threat +to himself with his drinking. required intubation in the past. +- has been seen recently by psychiatry in the past to evaluate +for possible section 35. + +Social History: +Drinks regularly, prefers listerine and vodka. Has been +drinking heavily since release from prison on [**8-9**]. +Homeless, lives on streets. Denies IVDU for >10yrs. Denies +cigs for>10 yrs. Denies SI or HI + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications. + +Physical Exam: +VS: 99.8 110 96% RA RR12 133/111 +gen: agitated but redirectable. +Neuro: aao to person, place, time, situation. +- cn ii-xii intact +- motor [**6-11**] bilat upper/lower +- slightly tremulous upper ex +- [**Last Name (un) 36**] to light touch +- gait wide based and unsteady +- f-n intact bilat +- h-s impaired bilat +heent: old scar on right forehead. mm dry, jvp flat +cards: tachy, reg, no murmurs +resp: ctab +abd: BS+ NT ND soft, no rebound, no stigmata of liver dz +Ext: no edema. good pulses + +Pertinent Results: +EKG: Sinus tachy, nl axis, nl intervals, no acute st-t changes. +. +Labs: +VBG: 7.49/33/58 +Lactate 3.1 +. +142 102 10 +----------------< 87 +4.1 22 0.9 +Ca: 9.4 Mg: 2.0 P: 2.9 +Serum EtOH 448 +Serum Benzo Pos +Serum ASA, Acetmnphn, Barb, Tricyc Negative +. +WBC: 9.5 +HCT: 35.7 - at baseline +PLT: 208 +N:64.2 L:30.8 M:3.5 E:1.1 Bas:0.5 +Urine Benzos, Barbs, Opiates, Cocaine, Amphet, Mthdne Negative +. +Repeat chemistry: +140 108 8 +-------------< 73 +3.3 20 0.7 +Ca: 8.0 Mg: 1.6 P: 1.9 +repeat lactate 3.1 + +Brief Hospital Course: +36M with ETOH dependence and frequent admissions for EtOH +intoxication presents with EtOH withdrawal. ICU-east course by +problem: +. +# Alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. Has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of DTs and w/d seizures, we treated +aggressively with valium in ICU. He received either 60-70 IV +valium in the ED. On arrival to the ICU, he was written for +valium 20mg PO q15m prn CIWA>10 and he received it almost as +frequently as written. He became less agitated after approx +80-100mg (in addition to the IV given in the ED) and then the +CIWA scale was spread out to 20mg PO prn q1h. He tolerated +this transition well. +- He received multivit, folate, thiamine in IVF then PO +- social work was consulted the morning after admission when +patient was demanding to leave. He felt he had enough valium +and actually refused another dose. We explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. He expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. He signed out +AMA with plans to seek outpatient treatment. +. +# Psych: No SI. We had plans to contact psychiatry morning +after admission particularly given his high valium need. +However, he expressed interest in leaving and we felt he had +capacity to make this decision. Social wk was involved but +psychiatry was not consulted. +. +# chest pain: EKG without ischemic changes. CP was reproducible +on palpation. Suspected MSK pain. He received one dose of +morphine for cp. We then treated with toradol, motrin, and +tylenol. We would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. His pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. Lactic acidosis not likely +given the alkalosis seen on VBG. Consider dehydration vs poor +quality sample. Infection less likely given no fever or +hypotension or any localizing signs of infection. Repeat +lactate remained 3.1. Etiology unclear and workup hindered by +patient leaving AMA. +. +# Anion gap: AG 18 in the ED with a normal HCO3 and alkalosis on +VBG. ASA negative as were other toxins. Difficult to interpret +but wonder if slightly increased AG is from the elevated +lactate. Repeat chemistries showed normal anion gap. +. +#Anemia - normocytic anemia, Hct at baseline +. +# PPx: Heparin sc tid, PPI given etoh abuse, bowel reg +. +# FEN: Regular diet, replete lytes prn, banana bag then IVF +. +# Access: PIV x1 +. +# Code: FULL +. +# Communication: Patient +. +# Dispo: Patient left AMA. + + +Medications on Admission: +none + +Discharge Medications: +none + +Discharge Disposition: +Home + +Discharge Diagnosis: +ETOH Intoxication/Withdrawal + + +Discharge Condition: +fair + + +Discharge Instructions: +You were admitted to the hospital because you were found +intoxicated by EMS. You were admitted to the ICU and treated +with Valium for withdrawal. You were advised to stay in the +hospital for continued care and treatment of withdrawal however +you decided against medical advice that you no longer wished to +receive care. You spoke with the social worker before you left +the hospital and were advised to return to [**Street Address(1) 5904**] Inn +to speak with your outreach worker there. + +You signed out against medical advise. + +Followup Instructions: +Please speak with the Outreach worker [**Street Address(1) 29735**] Inn. + +Please return to the hospital should you have any concerning +symptoms including difficulty breathing, falls or injuries +requiring medical attention, concerning withdrawal symptoms. + + + +",64,2181-08-20 20:26:00,2181-08-21 11:10:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ALCOHOL WITHDRAWAL," +36m with etoh dependence and frequent admissions for etoh +intoxication presents with etoh withdrawal. icu-east course by +problem: +. +# alcohol withdrawal: presented with signs of withdrawal with +agitation, hypertension, tachycardia, and slight tremor of upper +ex bilat. has gait unsteadiness which is likely [**3-10**] acute intox +but appears to be chronic based on records. +- given that he has hx of dts and w/d seizures, we treated +aggressively with valium in icu. he received either 60-70 iv +valium in the ed. on arrival to the icu, he was written for +valium 20mg po q15m prn ciwa>10 and he received it almost as +frequently as written. he became less agitated after approx +80-100mg (in addition to the iv given in the ed) and then the +ciwa scale was spread out to 20mg po prn q1h. he tolerated +this transition well. +- he received multivit, folate, thiamine in ivf then po +- social work was consulted the morning after admission when +patient was demanding to leave. he felt he had enough valium +and actually refused another dose. we explained to him that we +preferred that he stay for full evaluation and treatment of etoh +w/d and his electrolyte abnormalities. he expressed +understanding of our concerns and was able to verbalize the +risks and benefits of leaving against our advice. he signed out +ama with plans to seek outpatient treatment. +. +# psych: no si. we had plans to contact psychiatry morning +after admission particularly given his high valium need. +however, he expressed interest in leaving and we felt he had +capacity to make this decision. social wk was involved but +psychiatry was not consulted. +. +# chest pain: ekg without ischemic changes. cp was reproducible +on palpation. suspected msk pain. he received one dose of +morphine for cp. we then treated with toradol, motrin, and +tylenol. we would recommend avoiding narcotics in the future if +at all possible and if clinically indicated. his pain improved +when his agitation improved. +. +# elevated lactate: ddx included dehydration, infection, liver +disease, hypovolemia, poor sample. lactic acidosis not likely +given the alkalosis seen on vbg. consider dehydration vs poor +quality sample. infection less likely given no fever or +hypotension or any localizing signs of infection. repeat +lactate remained 3.1. etiology unclear and workup hindered by +patient leaving ama. +. +# anion gap: ag 18 in the ed with a normal hco3 and alkalosis on +vbg. asa negative as were other toxins. difficult to interpret +but wonder if slightly increased ag is from the elevated +lactate. repeat chemistries showed normal anion gap. +. +#anemia - normocytic anemia, hct at baseline +. +# ppx: heparin sc tid, ppi given etoh abuse, bowel reg +. +# fen: regular diet, replete lytes prn, banana bag then ivf +. +# access: piv x1 +. +# code: full +. +# communication: patient +. +# dispo: patient left ama. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Alkalosis; Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Acidosis; Chronic hepatitis C without mention of hepatic coma; Cocaine abuse, unspecified; Lack of housing; Anemia, unspecified; Other chest pain]" +5060,194191.0,24300,2181-08-21,24299,117340.0,2181-03-05,Discharge summary,"Admission Date: [**2181-2-24**] Discharge Date: [**2181-3-5**] + +Date of Birth: [**2144-9-28**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 358**] +Chief Complaint: +ETOH intoxication + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +36 year old homeless man with h/o polysubstance abuse and +frequent ICU admissions returns with alcohol intoxication. He +reports that he drank a large bottle of listerine and a fifth of +Vodka and then blacked out. He denies falling. Does report +getting in a recent fight several days ago, he was punched in +the chest and has had episodic chest pain/soreness since. He +also fell down and cut his face at some point after the fight. +On ROS he reports chest pain/tenderness, headache, burning pain +in his hands and feet that has been worsening for at least 7 +months, unsteady gait which he feels is worse when sober. He +denies hematemasis, hematochezia, melena. +He was most recently admitted for EtOh withdrawal from +[**Date range (1) 61602**] and left AMA after his valium dose was tapered. He +planned to go to Anchor House detox program in [**Location (un) 3320**], MA. He +re-presented to the ED on [**2-8**] and once sober, he was unwilling +to undergo detox; he was discharged. + +ED: VS on arrival T 98.9 HR 104 BP134/80 RR 16 96%RA. He was +negative for cocaine; positive for benzos and ETOH at 251. He +required 40 mg IV Valium, 1 mg PO lorazepam, and 5 mg PO valium +for tremulousness and tachycardia. He was given total of 3L IVF. +An RIJ was placed for poor PIV access. CXR confirmed its +placement. Cardiac enzymes were sent. He received a banana bag + + +Past Medical History: +Polysubstance abuse: ETOH, heroin, IVDU, benzodiazepines +Hepatitis C +Hepatitis B +Compartment syndrome RLE, [**2171**] +OCD and anxiety +Depression with hx suicidal ideations and attempts +Alcohol abuse, hx DTs and withdrawal seizures + + +Social History: +Drinks regularly, 1 bottle of listerine per day. Uses heroin and + +benzodiazepines occasionally. Homeless, living in the [**Location (un) **] +area. no IVDU since [**2167**]. no cigarrettes in >10 years. + + +Family History: +Father with depression and alcoholism. Mother died of DM +complications + +Physical Exam: +Vitals: afebrile, VSS +Gen: NAD +HEENT: PERRL, anicteric, MMM. +Neck: supple +Chest: clear +CV: regular +Abd: benign +Ext: no edema +Skin: No rash +Neuro: nonfocal +Psych: anxious +. + + +Pertinent Results: +admission Labs: +------------- +[**2181-2-24**] 09:45PM WBC-4.0# RBC-4.03* HGB-12.0* HCT-35.5* MCV-88 +MCH-29.9 MCHC-33.9 RDW-16.0* +[**2181-2-24**] 09:45PM NEUTS-33.9* LYMPHS-53.3* MONOS-6.3 EOS-5.5* +BASOS-1.0 +[**2181-2-24**] 09:45PM PLT COUNT-222 +[**2181-2-24**] 09:45PM OSMOLAL-370* +[**2181-2-24**] 09:45PM ETHANOL-252* +[**2181-2-24**] 09:45PM CALCIUM-8.6 PHOSPHATE-1.7* MAGNESIUM-1.4* +[**2181-2-24**] 09:45PM GLUCOSE-273* UREA N-11 CREAT-0.9 SODIUM-141 +POTASSIUM-3.3 CHLORIDE-100 TOTAL CO2-26 ANION GAP-18 + +[**2181-2-24**] CXR- There is a right CVL seen with the tip positioned +in the SVC and no PTX. The lungs are clear + +[**2181-2-25**] Head CT- IMPRESSION: + +No acute intracranial hemorrhage. Nearly completely opacified +partially visualized left maxillary sinus, as before. + +Discharge: +[**2181-2-28**] 04:13AM BLOOD WBC-7.5 RBC-4.20* Hgb-12.3* Hct-38.4* +MCV-92 MCH-29.4 MCHC-32.1 RDW-15.1 Plt Ct-200 +[**2181-2-28**] 04:13AM BLOOD Glucose-86 UreaN-9 Creat-0.8 Na-140 K-3.8 +Cl-106 HCO3-30 AnGap-8 +[**2181-2-26**] 04:18AM BLOOD ALT-44* AST-69* LD(LDH)-172 AlkPhos-104 +TotBili-0.5 +[**2181-2-28**] 04:13AM BLOOD Calcium-9.0 Phos-4.1 Mg-2.0 + + +Brief Hospital Course: +36M with ETOH dependence and frequent admissions for EtOH +intoxication presented with EtOH intoxication/withdrawl. ETOH +level 252 on admission. Initially admitted to the ICU for IV +valium. Required 120mg valium total over first 24 hours. Patient +tapered to PO valium and called out the general medical floor on +[**2181-2-28**]. Psychiatry consulted and recommended slow valium taper +and referral to [**Doctor Last Name **] house. Also recommended that patient +could follow-up at [**Location (un) 61603**] house (BHCHP day shelter) if he +complies to showing up to medical clinic after discharge. Mr. +[**Known lastname 24927**] was informed he may be considered for Section 35 if he +returns to the hospital for alcohol intoxication/withdrawal in +the future, as he is considered a risk to his own safety. +[**First Name8 (NamePattern2) 2048**] [**Last Name (NamePattern1) 11009**] House did not have beds to offer, and as an +alternative discharge plan was being arranged, Mr. [**Known lastname 24927**] left +AMA. + + +Medications on Admission: +He has not taken any prescriptions medications for about 6 +months. + +Discharge Medications: +none + +Discharge Disposition: +Home + +Discharge Diagnosis: +alcohol withdrawal and dependence + +Discharge Condition: +stable, but patient left AMA + +Discharge Instructions: +Pt left AMA. + +Followup Instructions: +Patient left AMA + + +",169,2181-02-24 19:23:00,2181-03-05 15:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,ETOH WITHDRAWAL," +36m with etoh dependence and frequent admissions for etoh +intoxication presented with etoh intoxication/withdrawl. etoh +level 252 on admission. initially admitted to the icu for iv +valium. required 120mg valium total over first 24 hours. patient +tapered to po valium and called out the general medical floor on +[**2181-2-28**]. psychiatry consulted and recommended slow valium taper +and referral to [**doctor last name **] house. also recommended that patient +could follow-up at [**location (un) 61603**] house (bhchp day shelter) if he +complies to showing up to medical clinic after discharge. mr. +[**known lastname 24927**] was informed he may be considered for section 35 if he +returns to the hospital for alcohol intoxication/withdrawal in +the future, as he is considered a risk to his own safety. +[**first name8 (namepattern2) 2048**] [**last name (namepattern1) 11009**] house did not have beds to offer, and as an +alternative discharge plan was being arranged, mr. [**known lastname 24927**] left +ama. + + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Chronic viral hepatitis B without mention of hepatic coma without mention of hepatitis delta; Dehydration; Alcoholic polyneuropathy; Opioid abuse, unspecified; Sedative, hypnotic or anxiolytic abuse, unspecified; Chronic hepatitis C without mention of hepatic coma; Lack of housing]" +6901,198044.0,16225,2133-09-03,16224,193108.0,2133-03-23,Discharge summary,"Admission Date: [**2133-3-14**] Discharge Date: [**2133-3-23**] + + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 134**] +Chief Complaint: +Weakness. + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +[**Age over 90 **] y year old man w/ pmh sinus node dysfunction s/p pacemaker +placement, afib, HTN, called 911 earlier today after slipping +off of his chair and falling to the ground. The patient was +unable to get up, and lay on the ground for several hours before +he was able to reach a phone. The patient reports fatigue and +weakness over the past several days. He lives by himself and +cares for himself, depending primarily on meals for wheels for +nutrition. The patient [**Age over 90 **] chest pain, shortness of breath, +fever, chills, brbpr, melena, dysuria. +. +In the ED, vitals were HR 124, BP 95/65. 97% RA. EKG showed afib +w/aberrancy vs. Vtach. CK was 1589, Trop was .05 (baseline). INR +was 12.9. Creatinine was 1.7, up from baseline 0.8. UA was +positive for UTI. Pt received 150 amiodarone. Also ceftriaxone, +2.5 SC vitamin K and 1 unit FFP. + + +Past Medical History: +HTN +GERD +Sinus node dysfunction --> DDD pacer +Atrial fibrillation s/p cardioversion +ORIF right leg +Cholecystectomy +Cataract removal +TURP +Aortic stenosis s/p AVR (St. [**Male First Name (un) 923**] porcine valve, [**10-8**]) +Carpal tunnel syndrome s/p release +Allergic rhinitis + + +Social History: +Mr. [**Known lastname 46286**] is a retired window cleaner. He quit smoking 20 +years ago and reports having smoked 1.5 packs per day for sixty +years. He estimates drinking about 3 alcoholic drinks per +month. He lives alone. + + +Family History: +Mr. [**Known lastname 46286**] [**Last Name (Titles) **] any contributory family history. + +Physical Exam: +VS: T 99.6, BP 105/70 , HR 120-130 , RR 18 , O2 96 % on RA +Gen: Elderly male Caucasian. Tired appearing but Oriented x3 and +pleasant. +Head: NCAT. +Eyes: Sclera anicteric. PERRL, EOMI. Conjunctiva pale. +Mouth furrowed, red tongue, no ulcerations seen. +Neck: Supple with JVP of 8 cm. +CV: Irregularly irregular, normal S1, S2. No S4, no S3. +Chest: Resp were unlabored, no accessory muscle use. Scattered +crackles, wheeze, rhonchi. +Abd: Obese, soft, NTND. No abdominial bruits. +Ext: [**12-3**]+ edema bilaterally. No femoral bruits. +Skin: 3x3 erythematous shallow ulcer on lateral RLE. Red rash +throughout perineal area. +Pulses: DP pulses 2+ bilaterally + + +Pertinent Results: +[**2133-3-13**] 09:25PM BLOOD WBC-13.2* RBC-4.82 Hgb-14.1 Hct-42.4 +MCV-88 MCH-29.3 MCHC-33.4 RDW-14.7 Plt Ct-219 +[**2133-3-19**] 06:20AM BLOOD WBC-9.1 RBC-4.27* Hgb-12.4* Hct-37.3* +MCV-87 MCH-29.0 MCHC-33.2 RDW-14.5 Plt Ct-161 +[**2133-3-13**] 09:25PM BLOOD PT-97.9* PTT-46.1* INR(PT)-12.9* +[**2133-3-19**] 06:20AM BLOOD PT-19.6* PTT-35.5* INR(PT)-1.8* +[**2133-3-13**] 09:25PM BLOOD Glucose-86 UreaN-79* Creat-1.7* Na-141 +K-5.5* Cl-105 HCO3-21* AnGap-21* +[**2133-3-19**] 05:59PM BLOOD Glucose-96 UreaN-17 Creat-0.8 Na-136 +K-4.1 Cl-101 HCO3-28 AnGap-11 +[**2133-3-13**] 09:25PM BLOOD ALT-181* AST-142* CK(CPK)-1589* +AlkPhos-162* TotBili-2.0* +[**2133-3-17**] 03:44AM BLOOD ALT-93* AST-42* LD(LDH)-422* AlkPhos-127* +TotBili-0.7 +[**2133-3-13**] 09:25PM BLOOD CK-MB-32* MB Indx-2.0 +[**2133-3-13**] 09:25PM BLOOD cTropnT-0.05* +[**2133-3-15**] 05:02AM BLOOD CK-MB-8 cTropnT-0.05* +[**2133-3-14**] 05:03AM BLOOD CK-MB-22* MB Indx-2.2 +[**2133-3-13**] 09:25PM BLOOD Calcium-9.5 Phos-4.7*# Mg-3.0* +[**2133-3-19**] 05:59PM BLOOD Calcium-7.6* Phos-2.0* Mg-1.9 +[**2133-3-13**] 09:25PM BLOOD TSH-5.0* +[**2133-3-13**] 09:25PM BLOOD Free T4-1.1 +[**2133-3-18**] 04:34AM BLOOD Digoxin-1.5 +[**2133-3-14**] 05:02AM URINE Color-Yellow Appear-Hazy Sp [**Last Name (un) **]-1.010 +[**2133-3-14**] 05:02AM URINE Blood-LG Nitrite-NEG Protein-TR +Glucose-NEG Ketone-TR Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-MOD +[**2133-3-14**] 05:02AM URINE RBC-21-50* WBC->50 Bacteri-MOD Yeast-NONE +Epi-[**2-4**] RenalEp-0-2 +[**2133-3-13**] 09:40PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.016 +[**2133-3-13**] 09:40PM URINE Blood-LG Nitrite-POS Protein-TR +Glucose-NEG Ketone-15 Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-MOD +[**2133-3-13**] 09:40PM URINE RBC-[**10-22**]* WBC-21-50* Bacteri-MOD +Yeast-NONE Epi-0-2 +[**2133-3-14**] 09:10AM URINE Hours-RANDOM Creat-64 Na-12 +[**2133-3-14**] 05:02AM URINE Hours-RANDOM Creat-32 Na-83 +[**2133-3-14**] 09:10AM URINE Osmolal-632 +. +CT HEAD W/O CONTRAST [**2133-3-14**] 12:10 AM + +CT HEAD W/O CONTRAST + +Reason: please assess for bleed + +[**Hospital 93**] MEDICAL CONDITION: +[**Age over 90 **] yo M presents with weakness. found to be in afib. +anticoagulated INR 12 +REASON FOR THIS EXAMINATION: +please assess for bleed +CONTRAINDICATIONS for IV CONTRAST: creat + +INDICATION: [**Age over 90 **]-year-old male with weakness and AFib with an INR +of 12. + +COMPARISON: [**2133-3-2**]. + +TECHNIQUE: Non-contrast head CT. + +FINDINGS: There is no hemorrhage, edema, mass effect, +hydrocephalus, or evidence of acute vascular territorial +infarct. The ventricular and sulcal prominence remains +unchanged. Hypodensities in the external capsule bilaterally are +stable and suggestive of lacunar infarct. The osseous structures +demonstrate no fractures. There is mucosal thickening within +multiple ethmoid air cells, the frontal air cells, as well as +maxillary sinuses with an 8-mm retention cyst in the left +maxillary sinus. The middle ear cavities and mastoid air cells +are clear. The soft tissues are unremarkable. + +IMPRESSION: No hemorrhage or mass effect. +. +CHEST (PORTABLE AP) [**2133-3-13**] 9:28 PM + +CHEST (PORTABLE AP) + +Reason: chf, pna + +[**Hospital 93**] MEDICAL CONDITION: +[**Age over 90 **] year old man with tachy, wide compl, rales +REASON FOR THIS EXAMINATION: +chf, pna +CHEST RADIOGRAPH PERFORMED ON [**2133-3-13**] + +Compared with prior study from [**2132-1-20**]. + +CLINICAL HISTORY: [**Age over 90 **]-year-old man with tachycardia, rales, +evaluate for CHF or pneumonia. + +FINDINGS: Portable upright chest radiograph is obtained. Midline +sternotomy wires are again noted as is the dual-lead right chest +pacemaker with lead tips in the proximal location of the right +atrium and right ventricle. The patient is slightly rotated to +the left, which somewhat limits evaluation. The +cardiomediastinal silhouette is stable with mild cardiac +enlargement again noted. There is a layering left pleural +effusion noted. Bibasilar atelectatic changes are noted as well. +There is no overt CHF. No definite pneumothorax is seen, +although the patient's chin overlies the left lung apex, +somewhat limiting evaluation. The visualized osseous structures +appear stable and intact. + +IMPRESSION: + +1. Stable cardiomegaly with left pleural effusion and bibasilar +atelectasis. +. +Atrial fibrillation with rapid ventricular response and +intraventricular +conduction defect with secondary ST-T wave abnormalities. +Compared to the +previous tracing of [**2131-12-28**] atrial fibrillation is new. +TRACING #1 + + Intervals Axes +Rate PR QRS QT/QTc P QRS T +118 0 160 354/455 0 -56 122 +. +The left atrium is moderately dilated. The right atrium is +markedly dilated. The estimated right atrial pressure is +10-20mmHg. There is moderate symmetric left ventricular +hypertrophy. The left ventricular cavity size is normal. There +is severe global left ventricular hypokinesis (LVEF = 25-30 %). +Right ventricular chamber size is normal. with mild global free +wall hypokinesis. The ascending aorta is mildly dilated. A +bioprosthetic aortic valve prosthesis is present. The aortic +valve prosthesis has normal transvalvular gradients. The mitral +valve leaflets are mildly thickened. There is severe mitral +annular calcification. There is a minimally increased gradient +consistent with trivial mitral stenosis. Trivial mitral +regurgitation is seen. [Due to acoustic shadowing, the severity +of mitral regurgitation may be significantly UNDERestimated.] +Moderate [2+] tricuspid regurgitation is seen. There is mild +estimated pulmonary artery systolic hypertension. There is no +pericardial effusion. + +Compared with the prior study (images reviewed) of [**2132-1-17**], +biventricular function is worse and the trans-aortic gradient +has decreased, possibly due to decreased cardiac output. +. +CHEST (PORTABLE AP) [**2133-3-19**] 7:44 AM + +CHEST (PORTABLE AP) + +Reason: interval change of effusion and pulm edema? + +[**Hospital 93**] MEDICAL CONDITION: +[**Age over 90 **] year old man with new CHF, vol overload. +REASON FOR THIS EXAMINATION: +interval change of effusion and pulm edema? +PORTABLE CHEST + +COMPARISON: [**2133-3-17**]. + +INDICATION: CHF. + +Congestive heart failure has [**Year (4 digits) 27836**] with increasing vascular +engorgement, perihilar edema, and enlarging pleural effusions. +Left pleural effusion is now moderate-to-large in size, and the +right effusion is small-to-moderate. + + + + +Brief Hospital Course: +[**Age over 90 **] y.o. male w/ pmh afib on coumadin, HTN, AS s/p porcine valve +replacement, dementia, found down at home, presenting with UTI, +ARF, rhabdomyolysis, and atrial fibrillation w/ aberancy. +. +#)Chronic systolic CHF: Patient presented with CHF exacerbation, +being total body fluid overloaded while being intravascularly +fluid depleted. His rhythm was atrial fibrillation with heart +rates of 120-130's. He was treated initially with fluids, as his +JVP was flat and he had negligible PO intake over the +preceeding three days. He was also started on amiodarone in an +attempt to cardiovert his rhythm. Echo showed LVEF 25-30% with +severe global LV hypokinesis. By hospital Day #2, he began to +develop crackles on lung exam and he was begun on a lasix drip +in an attempt to diurese his excess fluid. His amiodaorne was +discontinued as it was unsuccessful in cardioverting him to +sinus rhythm. The patient was then begun on digoxin. He was on +a lasix drip for three days and diuresed a total of 8L. The +patient maintained adequate blood pressure throughout diuresis. +The patient also had a pacer set at a rate of 80. EP was asked +to interrogate the pacer and lower his rate to 70, in an effort +to improve his symptoms of congestive heart failure. +Interrogation revealed that he spends the majority of his time +in atrial fibrillation. He is currently diuresing without +diuretics. Please monitor ins and outs. When he begins to get +even or positive/euvolemic (currently 2L negative without +diuretics), please start 20mg PO lasix and titrate for +euvolemia. He will need a follow-up ECHO in the next 6-8 weeks. +. +#)Atrial Fibrillation: Patient presented in atrial fibrillation +with rates up to 120-130's. His INR was also at 12.1. He was +administered fluids. He was initially begun on amiodarone, but +was discontinued after two days because it was unsuccessful in +cardioverting his rhythm. he was also administered ffp and +vitamin k to reverse his INR. Echo showed dilated left atrium +with a globally hypokinetic left ventricle with LVEF 25-30%. +Given his left atrial dilation, he was not considered a good +condidate for electrical cardioversion. He was next begun on +digoxin. After fluid administration and initiation of digoxin, +the patient's heart rate gradually slowed to 80-100. After +three days, he was restarted on coumadin to maintain a +therapeutic INR. His INR climbed to 2.9 on 5mg coumadin on the +day of discharge, so he should be given 4mg qday starting on the +evening of [**2133-3-23**]. Please check INR [**2133-3-28**]. Please give +results to staff physician and fax to PCP, [**Last Name (NamePattern4) **]. [**Last Name (STitle) **], [**First Name3 (LF) **] A, +Fax: [**Telephone/Fax (1) 6443**] Phone: [**Telephone/Fax (1) 1144**]. Titrate coumadin to INR +goal [**1-4**]. +. +#)Nutritional Status: patient is dependent on meals on wheels +for his nutrition. He reported not eating for several days prior +to admission. He was initially treated with thiamine, folate, +glucose, vitamin C, zinc supplements, along with a multivitamin. + He also received daily meals. After eating, his phosphate +decreased to 1.5. This was thought to be a manifestation of +refeeding syndrome and he was given phosphate supplements TID. +chem 10 on [**2133-3-28**]. Please give results to staff physician and +fax to PCP, [**Last Name (NamePattern4) **]. [**Last Name (STitle) **], [**First Name3 (LF) **] A, Fax: [**Telephone/Fax (1) 6443**] Phone: +[**Telephone/Fax (1) 1144**]. Titrate neutra phos to replete phosphate, can +discontinue when refeeding syndrome is improved. +. +#) Acute renal failure: Baseline cr 0.8. On admission Cr 1.7, +trended back to 0.9 atfer fluid administration. His ARF was +thought secondary to hypovolemia. +. +#) UTI: positive UA upon admission. he also presented with a +leukocytosis. He was begun on ceftriaxone for a UTI, and was +treated for 7 days. +. +#) Valvular disease, s/p AVR with [**First Name8 (NamePattern2) **] [**Male First Name (un) 1525**] porcine valve. +Patient's INR was initially reversed with ffp and vitamin K. His +coumadin was then restarted to maintain a therapeutic INR. +. +#) Elevated LFTs: AST and ALT elevation may be explained by mild +shock liver in setting of hypotension, no good explanation for +alk phos and elevated t bili. His liver enzymes an bilirubin +trended down to normal with stabilizing his hemodynamic status. +. +#) Lower Extremity Wounds: the patient had several ulcers on his +lower extremities. he was evaluated by wound care and treated +with daily dresing changes. +. +#) Code: FULL + +Medications on Admission: +Nystatin - 100,000 unit/gram Powder - apply to rash twice a day +Warfarin [Coumadin] - 5 mg Tablet - one Tablet(s) by mouth as +directed + + +Discharge Medications: +1. Hexavitamin Tablet Sig: One (1) Cap PO DAILY (Daily). +2. Ascorbic Acid 500 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +3. Zinc Sulfate 220 mg Capsule Sig: One (1) Capsule PO DAILY +(Daily). +4. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day) as needed for constipation. +6. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +7. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed for +constipation. +9. Potassium & Sodium Phosphates [**Telephone/Fax (3) 4228**] mg Powder in Packet +Sig: One (1) Powder in Packet PO TID WITH MEALS (). +10. labwork +INR and chem 10 on [**2133-3-28**]. +Titrate coumadin to INR goal [**1-4**]. +Titrate neutra phos to replete phosphate, can discontinue when +refeeding syndrome is improved. +Please give results to staff physician and fax to PCP, [**Last Name (NamePattern4) **]. +[**Last Name (STitle) **], [**First Name3 (LF) **] A, Fax: [**Telephone/Fax (1) 6443**] Phone: [**Telephone/Fax (1) 1144**] +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +12. Warfarin 2 mg Tablet Sig: Two (2) Tablet PO once a day. + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 85**] - [**Location (un) 86**] + +Discharge Diagnosis: +Primary: +- acute on chronic systolic congestive heart failure +- atrial fibrillation +- UTI +- hypophosphatemia +. +Secondary: +HTN +GERD +Sinus node dysfunction --> DDD pacer +ORIF right leg +Cholecystectomy +Cataract removal +TURP +Aortic stenosis s/p AVR (St. [**Male First Name (un) 923**] porcine valve, [**10-8**]) +Carpal tunnel syndrome s/p release +Allergic rhinitis +Dementia + + +Discharge Condition: +good, stable + + +Discharge Instructions: +Mr. [**Known lastname 46286**] was seen at [**Hospital1 18**] for heart failure and atrial +fibrillation. He was significantly fluid overloaded and he was +diuresed during his stay. His afib was control with digoxin +after amiodarone failed. He also had his pace maker changed to +pace at 70 bpm and his warfarin titrated for goal INR [**1-4**]. He +was also given a course of ceftriaxone for UTI. His potassium, +phosphate and calcium was being repleted for likely refeeding +syndrome. +. +He should be followed for: +- INR, titrate coumadin to goal INR [**1-4**] +- cardiopulmonary monitoring, specifically heart rate and blood +pressure +- weight gain +- PT/OT +- monitor phosphate, titrate or discontinue phosphate supplement +accordingly +. +INR and chem 10 on [**2133-3-28**]. +Titrate coumadin to INR goal [**1-4**]. +Titrate neutra phos to replete phosphate, can discontinue when +refeeding syndrome is improved. +Please give results to staff physician and fax to PCP, [**Last Name (NamePattern4) **]. +[**Last Name (STitle) **], [**First Name3 (LF) **] A, Fax: [**Telephone/Fax (1) 6443**] Phone: [**Telephone/Fax (1) 1144**] +. +Please monitor ins and outs. When he begins to get even or +positive/euvolemic (currently 2L negative without diuretics), +please start 20mg PO lasix and titrate for euvolemia. +. +His primary care provider should be called or he should return +to the emergency department if he experiences shortness of +breath, chest pain, lightheadedness, palpitations, fever greater +than 101.5 degrees F, or any other concerning symptoms. + +Followup Instructions: +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2133-4-30**] +3:30 +. +Provider: [**Name10 (NameIs) 1918**] [**Name11 (NameIs) **], MD Phone:[**Telephone/Fax (1) 902**] +Date/Time:[**2133-4-30**] 4:00. +- Please call Dr. [**Last Name (STitle) 1911**] for closer follow-up in the next +2-3 weeks. +. +Please follow-up with your primary care provider, [**Last Name (NamePattern4) **]. [**Last Name (STitle) **], in +the next 1-2 weeks. His number is [**Telephone/Fax (1) 1144**]. Please call +for an appointment. + + +",164,2133-03-14 00:58:00,2133-03-23 15:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,REHAB/DISTINCT PART HOSP,HYPOTENSION," +[**age over 90 **] y.o. male w/ pmh afib on coumadin, htn, as s/p porcine valve +replacement, dementia, found down at home, presenting with uti, +arf, rhabdomyolysis, and atrial fibrillation w/ aberancy. +. +#)chronic systolic chf: patient presented with chf exacerbation, +being total body fluid overloaded while being intravascularly +fluid depleted. his rhythm was atrial fibrillation with heart +rates of 120-130s. he was treated initially with fluids, as his +jvp was flat and he had negligible po intake over the +preceeding three days. he was also started on amiodarone in an +attempt to cardiovert his rhythm. echo showed lvef 25-30% with +severe global lv hypokinesis. by hospital day #2, he began to +develop crackles on lung exam and he was begun on a lasix drip +in an attempt to diurese his excess fluid. his amiodaorne was +discontinued as it was unsuccessful in cardioverting him to +sinus rhythm. the patient was then begun on digoxin. he was on +a lasix drip for three days and diuresed a total of 8l. the +patient maintained adequate blood pressure throughout diuresis. +the patient also had a pacer set at a rate of 80. ep was asked +to interrogate the pacer and lower his rate to 70, in an effort +to improve his symptoms of congestive heart failure. +interrogation revealed that he spends the majority of his time +in atrial fibrillation. he is currently diuresing without +diuretics. please monitor ins and outs. when he begins to get +even or positive/euvolemic (currently 2l negative without +diuretics), please start 20mg po lasix and titrate for +euvolemia. he will need a follow-up echo in the next 6-8 weeks. +. +#)atrial fibrillation: patient presented in atrial fibrillation +with rates up to 120-130s. his inr was also at 12.1. he was +administered fluids. he was initially begun on amiodarone, but +was discontinued after two days because it was unsuccessful in +cardioverting his rhythm. he was also administered ffp and +vitamin k to reverse his inr. echo showed dilated left atrium +with a globally hypokinetic left ventricle with lvef 25-30%. +given his left atrial dilation, he was not considered a good +condidate for electrical cardioversion. he was next begun on +digoxin. after fluid administration and initiation of digoxin, +the patients heart rate gradually slowed to 80-100. after +three days, he was restarted on coumadin to maintain a +therapeutic inr. his inr climbed to 2.9 on 5mg coumadin on the +day of discharge, so he should be given 4mg qday starting on the +evening of [**2133-3-23**]. please check inr [**2133-3-28**]. please give +results to staff physician and fax to pcp, [**last name (namepattern4) **]. [**last name (stitle) **], [**first name3 (lf) **] a, +fax: [**telephone/fax (1) 6443**] phone: [**telephone/fax (1) 1144**]. titrate coumadin to inr +goal [**1-4**]. +. +#)nutritional status: patient is dependent on meals on wheels +for his nutrition. he reported not eating for several days prior +to admission. he was initially treated with thiamine, folate, +glucose, vitamin c, zinc supplements, along with a multivitamin. + he also received daily meals. after eating, his phosphate +decreased to 1.5. this was thought to be a manifestation of +refeeding syndrome and he was given phosphate supplements tid. +chem 10 on [**2133-3-28**]. please give results to staff physician and +fax to pcp, [**last name (namepattern4) **]. [**last name (stitle) **], [**first name3 (lf) **] a, fax: [**telephone/fax (1) 6443**] phone: +[**telephone/fax (1) 1144**]. titrate neutra phos to replete phosphate, can +discontinue when refeeding syndrome is improved. +. +#) acute renal failure: baseline cr 0.8. on admission cr 1.7, +trended back to 0.9 atfer fluid administration. his arf was +thought secondary to hypovolemia. +. +#) uti: positive ua upon admission. he also presented with a +leukocytosis. he was begun on ceftriaxone for a uti, and was +treated for 7 days. +. +#) valvular disease, s/p avr with [**first name8 (namepattern2) **] [**male first name (un) 1525**] porcine valve. +patients inr was initially reversed with ffp and vitamin k. his +coumadin was then restarted to maintain a therapeutic inr. +. +#) elevated lfts: ast and alt elevation may be explained by mild +shock liver in setting of hypotension, no good explanation for +alk phos and elevated t bili. his liver enzymes an bilirubin +trended down to normal with stabilizing his hemodynamic status. +. +#) lower extremity wounds: the patient had several ulcers on his +lower extremities. he was evaluated by wound care and treated +with daily dresing changes. +. +#) code: full + + ","PRIMARY: [Congestive heart failure, unspecified] +SECONDARY: [Acute kidney failure, unspecified; Urinary tract infection, site not specified; Rhabdomyolysis; Ulcer of calf; Acute on chronic systolic heart failure; Disorders of phosphorus metabolism; Atrial fibrillation; Unspecified essential hypertension; Esophageal reflux; Cardiac pacemaker in situ; Heart valve replaced by transplant]" +7095,167836.0,8296,2200-03-26,8295,100931.0,2200-03-08,Discharge summary,"Admission Date: [**2200-3-7**] Discharge Date: [**2200-3-8**] + +Date of Birth: [**2123-7-21**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**Doctor First Name 1402**] +Chief Complaint: +hypotension + +Major Surgical or Invasive Procedure: +pacemaker placement + + +History of Present Illness: +76 year old male with DM, ESRD on HD via LUE AV fistula placed +[**12/2196**] s/p multiple stenoses and angioplasties with angioplasty +[**2200-1-16**] who is undergoing IV antibiotic therapy cefazolin at HD +for MSSA bacteremia of unclear duration and source. He was at HD + +today for his regular visit and was noted to have hypotension. +His pulse was then checked and found to be low, and his dialysis +was cut short by 2 hours and he was transferred to [**Hospital1 18**] ER for +further evaluation. +. +Upon presentation, pt denied complaints, but was noted to be in +complete heart block with a wide complex escape rhythm (RBBB +pattern) at 40 bpm. Known to have second degree AV block on EKG +prior. BP was 110/68 and RR 18 with sats 94%. Pacer pads were +placed. Carotid sinus massage and exercise were performed with +no prominent effect on AV nodal conduction. He was noted to have + +WCB that was likely in the His bundle. As a pacemaker was +recommended, ID was consulted due to recent +infection/bacteremia. +A TEE was performed and did not reveal any vegetations. He was +afebrile with negative Blood cx's since [**2-22**], maintained on Abx + +at dialysis. Went for PPM placement today and was complicated by +very difficult to access anatomy. In holding area post procedure +pt delirius and confused, needed a team of ten people to keep +control of him. Glucose was 17 on one measurement. Repeat was +200. He started the procedure with a glucose of 100. He had been +NPO all day awaiting the procedure.He remained confused even +after and was admitted to CCU for 1:1 monitoring. + + +Past Medical History: +-Diabetes mellitus 2 +-chronic kidney disease stage 4 on HD MWF +-Ulcerative colitis: no flares x 25 years +-Right adrenal adenoma. +-Gout. +-History of prostate cancer, status post prostatectomy. +-Remote history of nephrolithiasis. +-Hypertension +-Peripheral vascular disease s/p left [**Doctor Last Name **]-dp bypass +-carotid stenosis +-infrarenal abdominal aortic aneurysm +-deep venous thrombosis in [**2195**] +-iron deficiency anemia +-recent episode of aphasia which resolved - ? TIA + +Social History: +Quit smoking at age 73. Retired as a chemical mixer from a +leather tannery. No alcohol or illicit drug use. Lives at home +with his wife and family. + + +Family History: +Brother had liver cancer. Father and mother had cerebrovascular +accidents. Paternal grandfather rectal cancer. + +Physical Exam: +PE: T: 98.8 HR: 95 BP: 106/65 RR: 23 100% RA. +Neuro: PERRLA, A0X3 +CVS: [**12-18**] HSM heard best at apex +R chest: dressing over pacemaker C/D/I +Lungs: CTA-B +abd: +bs, soft, nt, nd +Ext: wwp,trace edema +pulses dopplerable + + + +Pertinent Results: +[**2200-3-7**] 11:28PM GLUCOSE-163* UREA N-25* CREAT-5.1*# +SODIUM-145 POTASSIUM-4.9 CHLORIDE-97 TOTAL CO2-38* ANION GAP-15 +[**2200-3-7**] 11:28PM ALT(SGPT)-0 AST(SGOT)-24 ALK PHOS-112 TOT +BILI-0.7 +[**2200-3-7**] 11:28PM CALCIUM-8.9 PHOSPHATE-3.3 MAGNESIUM-2.1 +[**2200-3-7**] 11:28PM WBC-11.9* RBC-2.84* HGB-7.8* HCT-27.3* MCV-96 +MCH-27.6 MCHC-28.7* RDW-25.9* +[**2200-3-7**] 11:28PM PLT COUNT-151 +[**2200-3-7**] 11:28PM PT-14.0* PTT-28.3 INR(PT)-1.2* +[**2200-3-7**] 11:50AM GLUCOSE-94 K+-4.0 +. +Echo [**2200-3-7**] +No spontaneous echo contrast or thrombus is seen in the body of +the left atrium/left atrial appendage or the body of the right +atrium/right atrial appendage. Right atrial appendage ejection +velocity is good (>20 cm/s). No atrial septal defect is seen by +2D or color Doppler. with mild global free wall hypokinesis. +There are complex (>4mm) atheroma in the aortic arch. There are +complex (>4mm) atheroma in the descending thoracic aorta. The +aortic valve leaflets (3) are mildly thickened. No masses or +vegetations are seen on the aortic valve. No aortic +regurgitation is seen. The mitral valve leaflets are mildly +thickened. No mass or vegetation is seen on the mitral valve. +Mild to moderate ([**12-14**]+) mitral regurgitation is seen. The +tricuspid valve leaflets are mildly thickened. There is at least +mild pulmonary artery systolic hypertension. No vegetation/mass +is seen on the pulmonic valve. There is no pericardial effusion. + +IMPRESSION: No valvular vegetations or peri-valvular abcesses +seen. Mild to moderate mitral regurgitation. Mildly depressed +left ventricular and moderately depressed right ventricular +systolic function. Complex plaque in descending aorta and aortic +arch. Mild pulmonary hypertension. +. +CXR [**2200-3-8**] - IMPRESSION: Evidence for mild vascular congestion +and very small pleural effusions. Cardiomegaly. A transvenous +pacemaker in place. + +Brief Hospital Course: +76 yo M w/ PMHx of HTN, DM, and ESRD on HD who was known to have +second degree AV block on prior EKG noted on admission to have +deteriorated to complete heart block. + +Altered Mental Status: His course post PM placement was +complicated by delirium, in the setting of hypoglycemia to 17. +He received an amp of d50 with improvement of his GFS to the +200s. He was delirious initially on the floor and per +discussions with his spouse he is confused at baseline. In +addition to the hypoglycemia, he may have been particularly +sensitive to sedating medications, and there may be some +metabolic component given his ESRD although his electrolytes +were not markedly abnormal. His GFS were checked every 4 hours, +he received repeated reorientation, and benzodiazepines were +avoided. His sensorium continued to improve. + +Complete heart block s/p Pacemaker: He had a [**Company **] DDD +pacemaker placed set at 60-120. He was appropriately V paced on +telemetry and subsequent EKG. He received a CXR the day +following his procedure showing that the leads were +appropriately positioned. EP interoggation post procedure showed +the pacemaker was working appropriately. He was instricted to +wear a slight to immobilize his right arm for several weeks post +procedure. A plan was made for him to follow up with the device +clinic within one week of discharge. He needs a new cardiologist +and the phone number for the cardiology clinic was given to him +to set up an appointment. + +ESRD on HD: He has ESRD on hemodialysis MWF. Due to his episode +of hypotension, his Friday hemodialysis session was terminated +prematurely, and he only received half of his dialysis. He was +discussed with our renal team and was not found to be grossly +volume overloaded nor were the electrolytes particularly +abnormal. Dialysis was deferred to his next scheduled session on +Monday. + +MSSA bacteremia: undergoing IV antibiotic therapy cefazolin at +HD for MSSA bacteremia of unclear duration and source. At this +point he is 13 days into his course. He should complete the +course of cefazolin decided by his nephrologists at dialysis. + +HTN: He was normotensive this hospitalization. His +antihypertensive regimen with metoprolol and lisinopril was +continued. + +Carotid stenosis /Infrarenal AAA/PVD: He was continued on asa, +simvastatin, lisinopril. + +Medications on Admission: +1. Albuterol Sulfate 2 puffs QID PRN +2. Calcium Acetate 667 mg Capsule Sig: Two (2) Capsule PO TIDAC + +3. Clopidogrel 75 mg PO q day +4. Fluticasone-Salmeterol 100-50 mcg/Dose [**Hospital1 **] +5. Lasix 40 mg PO BID +6. Glipizide 2.5 mg ER PO BID +7. Lisinopril 40 mg PO Q day +8. Metoprolol Tartrate 100 mg Tablet PO Q day +9. Ranitidine HCl 150 mg PO Q day +10. Silver Sulfadiazine 1 % Cream Sig: Q day +11. Simvastatin 10 mg Tablet PO Q HS +12. Aspirin 325 mg PO Q day +13. Folic Acid 1 mg PO Q day +14. B Complex-Vitamin C-Folic Acid 1 mg Capsule PO Q day +15. Cefazolin at HD + +Discharge Medications: +1. Albuterol Sulfate 90 mcg/Actuation HFA Aerosol Inhaler Sig: +1-2 Puffs Inhalation Q6H (every 6 hours) as needed for SOB. +2. Calcium Acetate 667 mg Capsule Sig: Two (2) Capsule PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +3. Clopidogrel 75 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Fluticasone-Salmeterol 100-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +5. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +6. Ranitidine HCl 150 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +7. Simvastatin 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +8. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +9. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. B Complex-Vitamin C-Folic Acid 1 mg Capsule Sig: One (1) Cap +PO DAILY (Daily). +11. Silver Sulfadiazine 1 % Cream Sig: One (1) Appl Topical +DAILY (Daily) as needed for apply to foot wounds. +12. Cefazolin 10 gram Recon Soln Sig: Two (2) grams IV Injection +HD PROTOCOL (HD Protochol). +13. Glipizide 2.5 mg Tablet Extended Rel 24 hr Sig: One (1) +Tablet Extended Rel 24 hr PO once a day. +Disp:*30 Tablet Extended Rel 24 hr(s)* Refills:*2* +14. Lisinopril 40 mg Tablet Sig: One (1) Tablet PO once a day. +15. Metoprolol Tartrate 100 mg Tablet Sig: One (1) Tablet PO +once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary. +Complete heart Block S/P pacemaker placement + +Secondary +End Stage Renal Disease +Diabetes + + +Discharge Condition: +Alert and oriented to person, place and time. Mildly confused. + +Discharge Instructions: +You were admitted to the hospital because you had dropped your +blood pressure during dialysis. You were found to have complete +heart block on EKG, a condition where the [**Doctor Last Name 1754**] of your heart +do not communicate electrically. For this reason, you had to +have a pacemaker placed. You were disoriented after the +procedure because your blood sugar was low however this has been +corrected. Some of the sedating medications may take some time +to wear off, so you may be a little confused intitially. Please +see your doctor if you still feel confused after a couple of +days. + +The following changes were made to your medications: +- DECREASE glipizide to 2.5mg ONCE a day. + +It is very important that you do not engage in any stretching or +lifting using your right arm. Please keep the pacemaker area +dry for 1 week. Please limit movement of your right arm and +wear the arm sling for six weeks. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] Clinic. Please follow up within one week of +discharge. The number to call to make your appointment is +[**Telephone/Fax (1) 62**]. + +You need a new cardiologist. Please call [**Hospital1 18**] cardiology at +([**Telephone/Fax (1) 2037**] to set up an appointment + +Provider: [**Last Name (NamePattern4) **]. [**First Name (STitle) **] [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 1142**] +Date/Time:[**2200-3-19**] 3:00 +Provider: [**First Name11 (Name Pattern1) 1037**] [**Last Name (NamePattern4) 2335**], MD Phone:[**Telephone/Fax (1) 457**] +Date/Time:[**2200-3-20**] 10:30 +Provider: [**Name10 (NameIs) 5536**] [**Name8 (MD) **], MD Phone:[**Telephone/Fax (1) 5537**] Date/Time:[**2200-4-17**] +8:30 + + + +",18,2200-03-07 16:24:00,2200-03-08 14:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,COMPLETE HEART BLOCK," +76 yo m w/ pmhx of htn, dm, and esrd on hd who was known to have +second degree av block on prior ekg noted on admission to have +deteriorated to complete heart block. + +altered mental status: his course post pm placement was +complicated by delirium, in the setting of hypoglycemia to 17. +he received an amp of d50 with improvement of his gfs to the +200s. he was delirious initially on the floor and per +discussions with his spouse he is confused at baseline. in +addition to the hypoglycemia, he may have been particularly +sensitive to sedating medications, and there may be some +metabolic component given his esrd although his electrolytes +were not markedly abnormal. his gfs were checked every 4 hours, +he received repeated reorientation, and benzodiazepines were +avoided. his sensorium continued to improve. + +complete heart block s/p pacemaker: he had a [**company **] ddd +pacemaker placed set at 60-120. he was appropriately v paced on +telemetry and subsequent ekg. he received a cxr the day +following his procedure showing that the leads were +appropriately positioned. ep interoggation post procedure showed +the pacemaker was working appropriately. he was instricted to +wear a slight to immobilize his right arm for several weeks post +procedure. a plan was made for him to follow up with the device +clinic within one week of discharge. he needs a new cardiologist +and the phone number for the cardiology clinic was given to him +to set up an appointment. + +esrd on hd: he has esrd on hemodialysis mwf. due to his episode +of hypotension, his friday hemodialysis session was terminated +prematurely, and he only received half of his dialysis. he was +discussed with our renal team and was not found to be grossly +volume overloaded nor were the electrolytes particularly +abnormal. dialysis was deferred to his next scheduled session on +monday. + +mssa bacteremia: undergoing iv antibiotic therapy cefazolin at +hd for mssa bacteremia of unclear duration and source. at this +point he is 13 days into his course. he should complete the +course of cefazolin decided by his nephrologists at dialysis. + +htn: he was normotensive this hospitalization. his +antihypertensive regimen with metoprolol and lisinopril was +continued. + +carotid stenosis /infrarenal aaa/pvd: he was continued on asa, +simvastatin, lisinopril. + + ","PRIMARY: [Atrioventricular block, complete] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Bacteremia; Renal dialysis status; Peripheral vascular disease, unspecified; Gout, unspecified; Methicillin susceptible Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Personal history of malignant neoplasm of prostate; Other alteration of consciousness; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes]" +8559,105407.0,16314,2153-08-26,16313,145304.0,2153-05-08,Discharge summary,"Admission Date: [**2153-4-24**] Discharge Date: [**2153-5-8**] + +Date of Birth: [**2090-1-18**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 3276**] +Chief Complaint: +abdominal pain, constipation + +Major Surgical or Invasive Procedure: +Right IJ central line placement +PICC placement +Transfusion of [**First Name3 (LF) **] products + + +History of Present Illness: +63-yo M with history of AS s/p AVR, PAF, [**Hospital **] transferred from +OSH with Hct drop, esophageal mass. He initially presented to +his PCP with constipation [**Name Initial (PRE) **] 3 weeks, with mild abd distention +and diffuse abd pain. Poor PO intake due to fear of abd pain. +Lost a few pounds x past few weeks. No n/v. About 1 week PTA, he +had abd and chest CT that showed retroperitoneal and +retro-mediastinal LAD. Was seen by GI, who found him to have +positive guaiac on exam and referred to [**Hospital3 **] ED, +where repeat abd CT again showed LAD with ?colonic obstruction, +which prompted a barium enema study that was negative for bowel +obstruction. Since the enema, he has had dark-colored diarrhea. +He also reports malaise x past few weeks. +. +He was admitted to [**Hospital3 **]. Labs were notable for WBC +25, Hct 22 (42 one week prior), plts 122. INR 3.0, Cr 1. For his +Hct drop, he received 4 units of pRBCs alogn with 2 units of +FFP. Hct increased to 26. He underwent an EGD which revealed a +lower esophageal mass which was oozing [**Hospital3 **]. Bx and brushings +were taken. Per GI, the patient was also having some hemoptysis, +raising suspicion for tracheoesophageal fistula. He was +hemodynamically stable, mentating well without any hematemesis, +hemoptysis, or rectal bleeding. He was transferred to [**Hospital1 18**] for +further management. + +On arrival, he was stable, alert, awake. +. +Review of sytems: +(+) Per HPI +(-) Denies fever, chills, night sweats. Denies headache, sinus +tenderness, rhinorrhea or congestion. Denied cough, shortness of +breath. Denied chest pain or tightness, palpitations. Denied +nausea, vomiting. No dysuria. Denied arthralgias or myalgias. + +Past Medical History: +AS s/p AVR (Booing valve) +PAF not on warfarin +hemachromatosis with regular phlebotomies; normal liver bx a few +months ago + +Social History: +Works as a dye maker. No smoking. Social drinking. + +Family History: +Mother had gastric ca and died of emphysema + +Physical Exam: +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: Regular rate and rhythm, normal S1 + S2, 3/6 systolic murmur +best heard at RUSB +Abdomen: soft, non-tender, moderately distended, slightly tense, +bowel sounds present, no rebound tenderness or guarding +Rectal: guaiac positive +Ext: Warm, well perfused, 2+ pulses, no clubbing, cyanosis or +edema + +Pertinent Results: +Admission Labs +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] WBC-24.0*# RBC-3.22* Hgb-9.9* Hct-28.0* +MCV-87# MCH-30.8 MCHC-35.5* RDW-17.4* Plt Ct-110*# +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] Neuts-57 Bands-14* Lymphs-8* Monos-2 +Eos-2 Baso-1 Atyps-0 Metas-8* Myelos-8* NRBC-7* +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] PT-17.7* PTT-34.9 INR(PT)-1.6* +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] Fibrino-75* +[**2153-4-24**] 08:20PM [**Year/Month/Day 3143**] FDP-320-640* +[**2153-4-25**] 09:39AM [**Month/Day/Year 3143**] Ret Aut-4.3* +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] Glucose-141* UreaN-43* Creat-0.8 Na-139 +K-4.6 Cl-103 HCO3-25 AnGap-16 +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] ALT-31 AST-78* LD(LDH)-1665* AlkPhos-193* +TotBili-1.5 +[**2153-4-24**] 07:50PM [**Year/Month/Day 3143**] Calcium-8.8 Phos-4.1# Mg-2.8* +UricAcd-7.4* + +Interim/Discharge Labs +[**2153-5-4**] 02:29PM [**Month/Day/Year 3143**] CEA-5432* +[**2153-4-25**] 12:32AM [**Month/Day/Year 3143**] Lactate-1.7 +[**2153-5-2**] 03:15AM [**Month/Day/Year 3143**] Albumin-2.0* Calcium-7.7* Phos-2.7 Mg-2.0 +[**2153-5-6**] 12:00AM [**Month/Day/Year 3143**] Albumin-2.5* Calcium-7.7* Phos-3.6 Mg-2.1 +[**2153-5-6**] 12:00AM [**Month/Day/Year 3143**] ALT-44* AST-33 LD(LDH)-621* AlkPhos-148* +TotBili-0.7 +[**2153-4-29**] 06:32AM [**Month/Day/Year 3143**] Glucose-192* UreaN-47* Creat-0.8 Na-147* +K-4.0 Cl-115* HCO3-25 AnGap-11 +[**2153-5-7**] 11:50PM [**Month/Day/Year 3143**] Glucose-115* UreaN-12 Creat-0.6 Na-138 +K-3.9 Cl-105 HCO3-26 AnGap-11 +[**2153-4-26**] 05:15AM [**Month/Day/Year 3143**] FDP-[**Telephone/Fax (1) 14007**]* +[**2153-5-2**] 07:31PM [**Month/Day/Year 3143**] Fibrino-367 +[**2153-5-7**] 01:00AM [**Month/Day/Year 3143**] Fibrino-326 +[**2153-4-26**] 02:45PM [**Month/Day/Year 3143**] Plt Smr-VERY LOW Plt Ct-53* LPlt-2+ +[**2153-4-26**] 05:47PM [**Month/Day/Year 3143**] PT-16.6* PTT-36.5* INR(PT)-1.5* +[**2153-4-30**] 07:51PM [**Month/Day/Year 3143**] PT-15.3* PTT-29.1 INR(PT)-1.4* +[**2153-5-7**] 01:00AM [**Month/Day/Year 3143**] PT-13.9* PTT-21.5* INR(PT)-1.2* +[**2153-5-7**] 11:50PM [**Month/Day/Year 3143**] Plt Ct-120* +[**2153-5-6**] 12:00AM [**Month/Day/Year 3143**] Neuts-72* Bands-4 Lymphs-9* Monos-6 Eos-1 +Baso-1 Atyps-0 Metas-7* Myelos-0 +[**2153-4-26**] 05:47PM [**Month/Day/Year 3143**] WBC-18.8* RBC-3.02* Hgb-9.1* Hct-25.2* +MCV-83 MCH-30.0 MCHC-36.1* RDW-18.0* Plt Ct-56* +[**2153-4-29**] 02:44AM [**Month/Day/Year 3143**] WBC-9.8 RBC-3.49* Hgb-10.5* Hct-30.4*# +MCV-87 MCH-30.0 MCHC-34.4 RDW-18.3* Plt Ct-83* +[**2153-4-30**] 05:08AM [**Month/Day/Year 3143**] WBC-6.3 RBC-2.85* Hgb-8.6* Hct-25.0* +MCV-88 MCH-30.3 MCHC-34.5 RDW-17.6* Plt Ct-58* +[**2153-5-2**] 07:31PM [**Month/Day/Year 3143**] WBC-4.4 RBC-3.13* Hgb-9.1* Hct-26.5* +MCV-85 MCH-29.1 MCHC-34.4 RDW-16.2* Plt Ct-68* +[**2153-5-7**] 11:50PM [**Month/Day/Year 3143**] WBC-3.3* RBC-3.16* Hgb-9.8* Hct-29.0* +MCV-92 MCH-31.0 MCHC-33.8 RDW-19.2* Plt Ct-120* + +Micro Data +[**Month/Day/Year **] cx no growth + +IMAGING +[**2153-4-25**] CXRIMPRESSION: AP chest compared to [**2147-2-4**]: +Diaphragm is elevated, lowering the lung volumes. Examination is +marked as an +upright view, this may not be the case. Nevertheless, no free +subdiaphragmatic gas is demonstrated. Colon and stomach are +distended with +gas. Lungs are grossly clear aside from mild left basal +atelectasis. +Moderate cardiomegaly is longstanding. No pneumothorax or +pleural effusion.\ + +[**2153-4-25**] KUB IMPRESSION: No definite evidence of obstruction. No +evidence of free air on +limited supine view. + +[**4-28**] Abdomen: Contrast material is again present throughout the +colon. There is distention +of the transverse colon measuring about 10 cm, compared to 8.4 +cm previously. +Contrast is seen distally within the rectosigmoid region and in +the descending +colon, both of which appear nondistended. Mildly prominent air- +filled loops +of small bowel are also present. + +[**2153-5-5**] Abdomen: Portable AP radiograph of the abdomen was +compared to [**2153-4-29**]. +On the current study, no evidence of large bowel dilatation has +been +demonstrated, but note is made that the upper abdomen was not +included in the +field of view. The currently imaged pattern of the bowel gas +distribution is +nonspecific and does not demonstrate any apparent abnormality. + +Brief Hospital Course: +63 year old gentleman with newly diagnosed esophageal +adenocarcinoma and upper GI bleed. + +1) GI Bleed/[**Year (4 digits) **] loss anemia: Patient developed GI bleed and +[**Year (4 digits) **] loss anemia due to bleeding from esophageal mass which was +complicated by thrombocytopenia and DIC as below. The patient +was admitted to the ICU from [**Hospital3 4107**] with a hematocrit +in the 20s requiring 23 unit [**Hospital3 **] transfusions while in the +ICU. Surgery, GI & Radiation/Oncology were consulted and the +patient underwent XRT which alleviated his bleeding. He did not +require tranfusions of [**Hospital3 **] for ~36 hours and was called out to +the Oncology floor. On the floor, he was transfused 2 unit PRBCs +intitially [**5-4**] then did not require any further transfusions. +His platelets also remained stable and DIC resolved. He was +started on PPI [**Hospital1 **] and continued on this at discharge. + +2) DIC: The patient presented with an INR of 3, fibrinogen near +100 and platelets in the 50s. The etiology of his DIC was felt +to be due to underlying tumor burden. He was transfused +multiple units of platelets, FFP and cryoprecipitate. As his +bleeding subsided with XRT, his DIC resolved as well. + +3) Esophageal Adenocarcinoma: The patient was diagnosed with +stage IV adenocarcinoma. Oncology was consulted and they +initiated 5FU/Oxalyplatin therapy in conjunction with XRT. He +will have an outpatient PET which was scheduled prior to +discharge and will follow up with Dr. [**Last Name (STitle) 3274**]. + +4) Afib: Pt had episodes of afib with RVR in the [**Hospital Unit Name 153**] responding +to diltizem but remained rate controlled on the floor in the +80s. He was continued on his previous metoprolol dosing at +discharge. + +5) Foot ulcerations: Pt developed maceration and erythema of his +feet bilaterally with lower extremity edema. Podiatry was unable +to see him prior to discharge in house but an appointment was +made with his outpatient podiatrist the following day after +discharge. + +6) Low grade fever: Pt had a low grade fever 2 days prior to +discharge but had no signs or symptoms of infection other than +possibly feet as above. He was afebrile 24 hours prior to +discharge off antibiotics and cx were negative and f/u arranged +with podiatry as above. + + +Medications on Admission: +metoprolol 25 mg PO bid +atorvastatin 40 mg qhs +acetaminophen +flexeril prn + +Discharge Medications: +1. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO twice +a day. +2. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +3. Bacitracin Zinc 500 unit/g Ointment Sig: One (1) Appl Topical +[**Hospital1 **] (2 times a day). +Disp:*1 tube* Refills:*2* +4. Metoclopramide 10 mg Tablet Sig: One (1) Tablet PO QIDACHS (4 +times a day (before meals and at bedtime)) as needed for nausea. +Disp:*100 Tablet(s)* Refills:*0* +5. Outpatient Lab Work +Please check CBC on Thursday [**2153-5-10**] and fax to Dr. [**Last Name (STitle) 3274**] at +[**Telephone/Fax (1) 22294**] +6. Atorvastatin 40 mg Tablet Sig: One (1) Tablet PO at bedtime. + + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital3 **] VNA + +Discharge Diagnosis: +Primary Diagnosis +Esophageal Adenocarcinoma +Acute [**Hospital3 **] loss anemia secondary to Esophageal cancer +Disseminated intravascular coagulation + +Secondary Diagnosis: +Paroxysmal atrial fibrillation + + +Discharge Condition: +Hemodynamically stable, HR 80s and regular,stable [**Hospital3 **] counts, +last transfused [**2153-5-4**], afebrile with low grade fever 100.8 on +[**2153-5-7**] + + +Discharge Instructions: +You were admitted to the the hospital with bleeding and problems +with [**Name2 (NI) **] clotting likely related to cancer in your esophagus. +You received [**Name2 (NI) **] and platelet transfusions in the intensive +care unit. You were then transferred to the regular oncology +floor and you did well with no further bleeding. You were seen +by physical therapy who recommended you have more physical +therapy at home. + +We made the following changes to your medications +We added Bacitracin +We added Pantoprazole 40mg PO BID +We added reglan as needed for nausea + +Please return to the ER or call your primary oncologist if you +develop chest pain, palpitations, shortness of breath, abdominal +pain, nausea, vomiting, [**Name2 (NI) **] in the stool or dark stools, or +any other concerning symptoms. + +Followup Instructions: +Dr. [**Name (STitle) 3548**] [**Doctor Last Name 776**], [**2153-6-6**], 11 AM, [**Hospital Ward Name 332**] Basement +(Radiation Oncology) + +Please follow up with Drs. [**Last Name (STitle) 3274**] and [**Name5 (PTitle) 1852**] [**0-0-**]. +You have an appointment on Tuesday [**5-15**] at 2pm, on [**Hospital Ward Name 23**] [**Location (un) 8939**]. + +Please follow up with the Podiatrist, Dr. [**Last Name (STitle) **] (who works +with Dr. [**Last Name (STitle) **] tomorrow [**2153-5-9**] at noon. Call [**0-0-**] if +you have any questions. + +You also have a PET scan scheduled for Friday [**5-11**]. You were +given information regarding this over the telephone + + + [**First Name8 (NamePattern2) 251**] [**Name8 (MD) **] MD [**MD Number(1) 3282**] + +",110,2153-04-24 18:26:00,2153-05-08 16:40:00,EMERGENCY,TRANSFER FROM HOSP/EXTRAM,HOME HEALTH CARE,GASTROINTESTINAL BLEED," +63 year old gentleman with newly diagnosed esophageal +adenocarcinoma and upper gi bleed. + +1) gi bleed/[**year (4 digits) **] loss anemia: patient developed gi bleed and +[**year (4 digits) **] loss anemia due to bleeding from esophageal mass which was +complicated by thrombocytopenia and dic as below. the patient +was admitted to the icu from [**hospital3 4107**] with a hematocrit +in the 20s requiring 23 unit [**hospital3 **] transfusions while in the +icu. surgery, gi & radiation/oncology were consulted and the +patient underwent xrt which alleviated his bleeding. he did not +require tranfusions of [**hospital3 **] for ~36 hours and was called out to +the oncology floor. on the floor, he was transfused 2 unit prbcs +intitially [**5-4**] then did not require any further transfusions. +his platelets also remained stable and dic resolved. he was +started on ppi [**hospital1 **] and continued on this at discharge. + +2) dic: the patient presented with an inr of 3, fibrinogen near +100 and platelets in the 50s. the etiology of his dic was felt +to be due to underlying tumor burden. he was transfused +multiple units of platelets, ffp and cryoprecipitate. as his +bleeding subsided with xrt, his dic resolved as well. + +3) esophageal adenocarcinoma: the patient was diagnosed with +stage iv adenocarcinoma. oncology was consulted and they +initiated 5fu/oxalyplatin therapy in conjunction with xrt. he +will have an outpatient pet which was scheduled prior to +discharge and will follow up with dr. [**last name (stitle) 3274**]. + +4) afib: pt had episodes of afib with rvr in the [**hospital unit name 153**] responding +to diltizem but remained rate controlled on the floor in the +80s. he was continued on his previous metoprolol dosing at +discharge. + +5) foot ulcerations: pt developed maceration and erythema of his +feet bilaterally with lower extremity edema. podiatry was unable +to see him prior to discharge in house but an appointment was +made with his outpatient podiatrist the following day after +discharge. + +6) low grade fever: pt had a low grade fever 2 days prior to +discharge but had no signs or symptoms of infection other than +possibly feet as above. he was afebrile 24 hours prior to +discharge off antibiotics and cx were negative and f/u arranged +with podiatry as above. + + + ","PRIMARY: [Malignant neoplasm of other specified part of esophagus] +SECONDARY: [Defibrination syndrome; Acute posthemorrhagic anemia; Hematemesis; Hyperosmolality and/or hypernatremia; Thrombocytopenia, unspecified; Ulcer of other part of foot; Atrial fibrillation; Fever, unspecified; Leukocytopenia, unspecified; Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Heart valve replaced by other means]" +10774,142104.0,8553,2140-10-30,8551,146298.0,2140-09-12,Discharge summary,"Admission Date: [**2140-9-7**] Discharge Date: [**2140-9-12**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 30062**] +Chief Complaint: +melana, chest pain + +Major Surgical or Invasive Procedure: +Esophagogastroduodenoscopy + + +History of Present Illness: +72 year old male with CAD s/p CABG, atrial fib on coumadin, s/p +VT/VF arrest with BiV pacer; CHF with EF 15% admitted to the +MICU ([**9-7**]) after presenting with CP, SOB, abdominal pain, +melena, INR of 3, and Hct drop from 40 to 37. He was admitted to +the MICU where he was given FFP and 1u PRBCs and ruled out for +ACS. He was seen by GI, Surgery, and Cardiology. GI c/s resulted +in plan for EGD. Surgery c/s resulted in INR reversal and serial +exams and hcts. Cardiology felt the patient's CP was not [**2-13**] a +cardiac etiology. He was ruled out for MI regardless. His Hct +was 31 at its lowest but remained stable and, as he was stable +overall, he was felt appropriate for transfer to the floor for +further work up of his melena. +. +Of note, last [**Month (only) 547**], the patient had a similar presentation and +EGD, c-scope, and capsule endoscopy demonstrated gastritis, +Barrett's, diverticulosis and grade 1 hemorrhoids were found, +without any active bleeding. +At time of transfer, the patient endorsed mild abdominal pain +and diaphoresis. He denied chest pain. He had not had a BM in 2 +days. + + +Past Medical History: +--CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +--s/p VT/VF arrest, s/p ICD placement in [**2135**] +--Ischemic cardiomyopathy with an ED of 20%, s/p BiV pacer [**10-18**] + +--Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +--PAF +--CKD with baseline Cr. 1.6-2 +--Hyperlipidemia +--Asthma +--Anxiety +--Alzheimer's dementia +--Hypothyroidism +--GI bleed of unknown etiology [**2138**]. EGD revealed esophagitis, +Barrett's esophagus, and duodenitis. No ulcers. +--Diverticulosis +--GERD +--S/P Cholecystectomy + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Worked as an off-set printer in [**Location (un) 686**], where he +continues to live with his wife. Father of five children. +Retired 6 years ago, and since his recent heart problems, says +he rarely leaves the house. Most of his time is spent in front +of the television with his wife handling their affairs at home. +No history of smoking, past or present. Patient was a heavy +drinker until 20 years ago, when he stopped completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + + +Family History: +Non-contributory. + +Physical Exam: +Afebrile, 115/69, 75, 18, 99%2L +General Appearance: Pleasant, obese male, mildly diaphoretic +lying in bed in no acute distress. +Eyes / Conjunctiva: PERRL, EOMI, no icterus +Head, Ears, Nose, Throat: NCAT, MMMI, JVD 10cm +Cardiovascular: paced, [**3-17**] looud blowing systolic murmur loudest +at LUSB with radiation along the left sternal border throughout, +large, prolonged and displaced PMI +Respiratory / Chest: CTA b/l +Abdominal: Soft, mild guarding, +BS, subumbilical tenderness +with mild tenderness in bl lower quadrents, no guarding +Extremities: pneumoboots in place, dps 1+ bl +Neurologic: Attentive, Follows simple commands, a and o times 3, +movement and sensation intact in all extremities + + + + +Pertinent Results: +[**2140-9-7**] 03:20PM PT-29.2* PTT-31.4 INR(PT)-3.0* +[**2140-9-7**] 03:20PM PLT COUNT-168 +[**2140-9-7**] 03:20PM NEUTS-75.5* LYMPHS-13.8* MONOS-7.0 EOS-3.4 +BASOS-0.4 +[**2140-9-7**] 03:20PM WBC-8.6 RBC-4.30* HGB-12.4* HCT-37.0* MCV-86 +MCH-28.8 MCHC-33.5 RDW-14.6 +[**2140-9-7**] 03:20PM DIGOXIN-0.9 +[**2140-9-7**] 03:20PM CALCIUM-9.0 PHOSPHATE-3.1 MAGNESIUM-2.3 +[**2140-9-7**] 03:20PM CK-MB-4 +[**2140-9-7**] 03:20PM cTropnT-0.01 +[**2140-9-7**] 03:20PM LIPASE-44 +[**2140-9-7**] 03:20PM ALT(SGPT)-20 AST(SGOT)-28 CK(CPK)-112 ALK +PHOS-89 TOT BILI-0.2 +[**2140-9-7**] 03:20PM estGFR-Using this +[**2140-9-7**] 03:20PM GLUCOSE-72 UREA N-23* CREAT-1.7* SODIUM-138 +POTASSIUM-4.5 CHLORIDE-101 TOTAL CO2-32 ANION GAP-10 +[**2140-9-7**] 03:32PM K+-4.6 +[**2140-9-7**] 03:32PM COMMENTS-GREEN TOP +[**2140-9-7**] 06:02PM HCT-35.6* +[**2140-9-7**] 06:12PM LACTATE-0.9 +[**2140-9-7**] 11:30PM HCT-31.1* +[**2140-9-7**] 11:30PM URINE HOURS-RANDOM UREA N-377 CREAT-52 +SODIUM-50 +[**2140-9-7**] 11:30PM DIGOXIN-0.8* +[**2140-9-7**] 11:30PM MAGNESIUM-2.0 +[**2140-9-7**] 11:30PM CK-MB-4 cTropnT-0.01 +[**2140-9-7**] 11:30PM CK(CPK)-110 +[**2140-9-7**] 11:30PM GLUCOSE-89 UREA N-20 CREAT-1.6* SODIUM-141 +POTASSIUM-4.2 CHLORIDE-104 TOTAL CO2-30 ANION GAP-11 + +EKG - [**9-7**]: Ventricular paced rhythm +Atrial mechanism uncertain - may be paced ot possible ectopic +atrial rhythm +Since previous tracing of [**2140-4-19**], ventricular ectopy absent and +P wave +morphology appears changed + +CXR - [**9-7**]: SINGLE PORTABLE UPRIGHT VIEW OF THE CHEST: The +cardiomediastinal contour is +unchanged, with moderate cardiomegaly. There is no pleural +effusion or +evidence of focal consolidation. The dual-lead pacing device is +unchanged in appearance. Osseous structures are unremarkable. +IMPRESSION: No significant change since [**2140-4-12**]. No evidence +of pneumonia or congestive heart failure. + +KUB - [**9-9**]: FINDINGS: There is non-specific bowel gas in the +abdomen. There are no distended loops of bowel, or concerning +air-fluid levels. There is air in the rectum. There is a large +amount of feces in the descending colon, suggesting +constipation. Of note, there is a right hip hemiarthroplasty +hardware, without apparent hardware complication. There is a +mild lumbar levoscoliosis. There are surgical clips at the right +upper quadrant, from prior cholecystectomy. There are wires +projected on to the heart, likely pacer wires. +IMPRESSION: No evidence of bowel obstruction. Likely +constipation. + +EGD - [**9-9**]: Barrett's Exophagitis, Gastritis, Duodenitis + + +Brief Hospital Course: +72 year old male with CAD s/p CABG, atrial fib on coumadin, s/p +VT/VF arrest now with BiV pacer; CHF with EF 15% who presented +with what appears to be non-cardiac chest pain, abdominal pain +and melena. +. +# Melena/Abdominal pain: HCT decreased to 31 from BL of 33 on +arrival to MICU. INR was reversed. Serial hematocrits were +checked and remained stable despite the patient remaining guiac +positive. Aspirin and Coumadin were held until after EGD at +which time they were restarted. IV PPI was given until EGD. +Patient was converted to PO PPI [**Hospital1 **] and instructed to continue +as such for six weeks. GI follow up [**Hospital1 1988**]. Patient had +similar episode in [**4-19**] and had an extensive GI workup which was +negative. +. +# Chest Pain: Pain resolved by the time the patient arrived to +the floor. Cardiology felt the pain was unlikely to be cardiac +in nature as cardiac enzymes were negative on arrival to the ED +after 5 hours of constant chest pain. Pain could be esophageal +as patient has history of Esophagitis and Barretts esophagus. +Last possibility is aortic chest pain as patient has history of +thoracic aortic aneurysm repair, small concern for dissection +although unlikely as patient remained stable throughout his +hopitalization and his CP resolved. +. +# CAD: Patient is s/p CABG. Chest pain unlikely to be cardiac. +MI ruled out. ASA, BB and statin were initially held in setting +of possible GIB but were restarted prior to discharge. +. +# CHF: Patient with history of ischemic CMP with EF 15%. Home +Lasix, Aldactone, and Toprol were intially held but reintroduced +prior to discharge. Home digoxin was continued. +. +# PAF: Patient s/p BiV pacer placement on Coumadin. INR was +reversed intially but coumadin was restarted prior to discharge. +Digoxin was continued. +. +# VF/VT arrest: Patient is s/p BiV pacer/ICD placement. Home +Sotalol, Mexiletine were continued. +. +# Asthma: Albuterol MDI at home. Albuterol Nebs were given PRN. +. +# Hypothyroidism: Home levoxyl was continued. +. +# CKD: Patient with Cr of 1.7 on admission with Baseline Cr +1.5-2. Remained stable. +. +# Alzheimer??????s: Held home Donepezil, Celexa initially. Restarted +prior to discharge. + +Medications on Admission: +Sotalol 80mg [**Hospital1 **] + +Lipitor 20mg daily + +Donepezil 5mg daily + +Quetiapine 25mg, 3tabs qAM, 1tab noon, 3tabs qHS + +Celexa 60mg daily + +Protonix 40mg daily + +ASA 81mg daily + +Clonazepam 0.5mg TID PRN + +Lisinopril 5mg daily + +Digoxin 125mcg, [**1-13**] tab daily + +K-Dur daily + +Spironolactone 25mg daily + +Levothyroxin3e 112mcg daily + +Trazodone 25mg qHS + +Mexiletine 150mg TID + +Albuterol MDI 2puf q6hPRN + +Fluticasone 110mcg 2puff [**Hospital1 **] + +Toprol SL 50mg daily + +Lasix 40mg TID + +Coumadin + + +Discharge Medications: +1. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +2. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +3. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +5. Digoxin 125 mcg Tablet Sig: [**1-13**] Tablet PO DAILY (Daily). +6. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at bedtime) +as needed. +7. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours): +Take twice per day for a total of 6 weeks. Can then resume once +per day. +Disp:*45 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +8. Warfarin 1 mg Tablet Sig: 2-3 Tablets PO once a day: 2 to 3 +tablets by mouth once per day or as directed. +9. Albuterol 90 mcg/Actuation Aerosol Sig: Two (2) puffs +Inhalation every six (6) hours as needed for shortness of breath +or wheezing. +10. Lipitor 20 mg Tablet Sig: One (1) Tablet PO once a day. +11. Celexa 40 mg Tablet Sig: 1.5 Tablets PO once a day. +12. Donepezil 5 mg Tablet Sig: One (1) Tablet PO at bedtime. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) puffs +Inhalation twice a day. +14. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +15. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO once a day. +16. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +17. Miralax 100 % Powder Sig: One (1) packet PO once a day. +18. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +19. Quetiapine 25 mg Tablet Sig: Two (2) Tablet PO qam. +20. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO qnoon. +21. Quetiapine 25 mg Tablet Sig: Three (3) Tablet PO at bedtime. + +22. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +23. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO once a day. +24. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +25. Promethazine 12.5 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for nausea. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Upper GastroIntestinal Bleed +Barrett's Esophagitis +Gastritis +Duodenitis + +Discharge Condition: +Fair + + +Discharge Instructions: +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +Adhere to 2 gm sodium diet +Fluid Restriction: 2L + +You were admitted to the hospital because you had blood in your +stool along with a decrease in your blood count/hematocrit +concerning for ongoing bleeding. Because you also had chest pain +upon presentation, you were also admitted to rule out the +possibility that you were experiencing a heart attack. + +You had an EGD performed which showed irritation and +inflammation of your esophagus, stomach, and duodenum. This +irritation could be the cause of your bloody stool and decrease +in blood count. You were given blood replacement products along +with high doses of protonix and your blood count remained +stable. You should continue to take you protonix twice per day +for the next 6 weeks. You have follow up with the GI doctors +[**Name5 (PTitle) 1988**]. + +You should call your doctor and/or return to the emergency room +if you have dark tarry stools or bright red blood in your stool, +Chest Pain, Shortness of Breath, or any other corncerning +symptoms. + +Followup Instructions: +[**9-14**] at 9:30am DEVICE CLINIC (Phone:[**Telephone/Fax (1) 59**]) + +[**9-14**] at 10:00am [**First Name8 (NamePattern2) 1903**] [**Last Name (NamePattern1) 1904**], NP (Phone:[**Telephone/Fax (1) 62**]) + +[**9-30**] at 11:00 [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD (Phone:[**Telephone/Fax (1) 463**]) + + + +",48,2140-09-07 21:07:00,2140-09-12 17:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN," +72 year old male with cad s/p cabg, atrial fib on coumadin, s/p +vt/vf arrest now with biv pacer; chf with ef 15% who presented +with what appears to be non-cardiac chest pain, abdominal pain +and melena. +. +# melena/abdominal pain: hct decreased to 31 from bl of 33 on +arrival to micu. inr was reversed. serial hematocrits were +checked and remained stable despite the patient remaining guiac +positive. aspirin and coumadin were held until after egd at +which time they were restarted. iv ppi was given until egd. +patient was converted to po ppi [**hospital1 **] and instructed to continue +as such for six weeks. gi follow up [**hospital1 1988**]. patient had +similar episode in [**4-19**] and had an extensive gi workup which was +negative. +. +# chest pain: pain resolved by the time the patient arrived to +the floor. cardiology felt the pain was unlikely to be cardiac +in nature as cardiac enzymes were negative on arrival to the ed +after 5 hours of constant chest pain. pain could be esophageal +as patient has history of esophagitis and barretts esophagus. +last possibility is aortic chest pain as patient has history of +thoracic aortic aneurysm repair, small concern for dissection +although unlikely as patient remained stable throughout his +hopitalization and his cp resolved. +. +# cad: patient is s/p cabg. chest pain unlikely to be cardiac. +mi ruled out. asa, bb and statin were initially held in setting +of possible gib but were restarted prior to discharge. +. +# chf: patient with history of ischemic cmp with ef 15%. home +lasix, aldactone, and toprol were intially held but reintroduced +prior to discharge. home digoxin was continued. +. +# paf: patient s/p biv pacer placement on coumadin. inr was +reversed intially but coumadin was restarted prior to discharge. +digoxin was continued. +. +# vf/vt arrest: patient is s/p biv pacer/icd placement. home +sotalol, mexiletine were continued. +. +# asthma: albuterol mdi at home. albuterol nebs were given prn. +. +# hypothyroidism: home levoxyl was continued. +. +# ckd: patient with cr of 1.7 on admission with baseline cr +1.5-2. remained stable. +. +# alzheimer??????s: held home donepezil, celexa initially. restarted +prior to discharge. + + ","PRIMARY: [Hemorrhage of gastrointestinal tract, unspecified] +SECONDARY: [Paroxysmal ventricular tachycardia; Chronic systolic heart failure; Congestive heart failure, unspecified; Other chest pain; Esophageal reflux; Unspecified acquired hypothyroidism; Aortocoronary bypass status; Duodenitis, without mention of hemorrhage; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Asthma, unspecified type, unspecified; Other and unspecified hyperlipidemia; Chronic kidney disease, unspecified; Barrett's esophagus; Unspecified gastritis and gastroduodenitis, without mention of hemorrhage; Long-term (current) use of anticoagulants; Other specified forms of chronic ischemic heart disease; Automatic implantable cardiac defibrillator in situ; Atrial fibrillation]" +10774,142104.0,8553,2140-10-30,8552,130230.0,2140-10-18,Discharge summary,"Admission Date: [**2140-10-11**] Discharge Date: [**2140-10-18**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 898**] +Chief Complaint: +Black stools, chest pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Pt is a 72 yo M with PMH of CAD s/p CABG and PCI to L circ, AS, +VT/VF arrest with BiV pacer, CHF (EF 20%), afib on coumadin, CRI +(BL Cr 1.6-2), and diverticulosis. H/O GIB w most recent +admission on [**2140-9-12**]. Now with black stools since MN accompanied +by mid-sternal CP with radiation to left arm. Took all BP meds +this AM (per pt, usual BP in the 90s range). Also c/o +lightheadedness and SOB. +. +In the ED, VS: T 98 BP 105/76 HR 75 RR 21 97%2L. Guaiac pos +black stool. Patient received morphine for CP with mild +improvement in pain. EKG was v-paced with no obvious ST/TW +changes. NG lavage was negative x 2. He received 2U FFP and 5 mg +PO vitamin K for INR reversal and 1L IVFs. Seen by Cards in ED, +recommennd echo in AM, +. +On arrival to the MICU, pt states his discomfort has imporved,d +own from [**8-21**] to [**4-21**], described as dull ache in chest, +non-radiating, constant since 11 PM last night, as well as +discomfort in the lower abdomen (identical to past abd pain in +setting of past GIB x 2). + nausea. + + +Past Medical History: +--CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +--s/p VT/VF arrest, s/p ICD placement in [**2135**] +--Ischemic cardiomyopathy with an ED of 20%, s/p BiV pacer [**10-18**] + +--Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +--PAF +--CKD with baseline Cr. 1.6-2 +--Hyperlipidemia +--Asthma +--Anxiety +--Alzheimer's dementia +--Hypothyroidism +--GI bleed of unknown etiology [**2138**]. EGD revealed esophagitis, +Barrett's esophagus, and duodenitis. No ulcers. +--Diverticulosis +--GERD +--S/P Cholecystectomy + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Worked as an off-set printer in [**Location (un) 686**], where he +continues to live with his wife. Father of five children. +Retired 6 years ago, and since his recent heart problems, says +he rarely leaves the house. Most of his time is spent in front +of the television with his wife handling their affairs at home. +No history of smoking, past or present. Patient was a heavy +drinker until 20 years ago, when he stopped completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + + +Family History: +Non-contributory. + +Physical Exam: +VS: afebrile Heart rate: 75 paced Normotensive and satting +well on room air +GEN: Elderly male, NAD, lying in bed +HEENT: PERRL, anicteric +NECK: Supple, no JVD +CHEST: CTAB +CV: s1s2 + SEM, + heave with lateral displacement of the PMI +ABD: +BS, soft, ND, mild TTP lower quadrants bilaterally, no +rebound or guarding +BACK: No CVAT +Rectak: Trace guaiac positive black stool +EXT: WD/WP, no pedal edema +NEURO: A&O x 3, MAE, speech fluent, nonfocal + + +Pertinent Results: +CBC: +[**2140-10-11**] 12:45PM BLOOD WBC-9.9 RBC-4.59* Hgb-13.3* Hct-39.8* +MCV-87 MCH-29.1 MCHC-33.5 RDW-14.2 Plt Ct-149* +[**2140-10-13**] 06:38AM BLOOD WBC-7.8 RBC-4.02* Hgb-11.7* Hct-34.7* +MCV-87 MCH-29.0 MCHC-33.6 RDW-14.0 Plt Ct-121* +[**2140-10-18**] 05:27AM BLOOD WBC-6.6 RBC-4.06* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.2 MCHC-33.8 RDW-14.9 Plt Ct-152 + +Coags: +[**2140-10-11**] 12:45PM BLOOD PT-24.7* PTT-29.8 INR(PT)-2.4* +[**2140-10-14**] 04:45AM BLOOD PT-18.4* PTT-29.4 INR(PT)-1.7* +[**2140-10-17**] 04:55AM BLOOD PT-15.2* PTT-31.5 INR(PT)-1.3* + +Chemistry: +[**2140-10-11**] 12:45PM BLOOD Glucose-102 UreaN-31* Creat-2.0* Na-140 +K-3.9 Cl-100 HCO3-30 AnGap-14 +[**2140-10-13**] 06:38AM BLOOD Glucose-68* UreaN-26* Creat-1.5* Na-142 +K-4.1 Cl-103 HCO3-27 AnGap-16 +[**2140-10-18**] 05:27AM BLOOD Glucose-85 UreaN-22* Creat-1.7* Na-141 +K-3.9 Cl-102 HCO3-30 AnGap-13 +[**2140-10-11**] 12:45PM BLOOD Calcium-9.5 Phos-2.7 Mg-2.2 +[**2140-10-14**] 04:45AM BLOOD Calcium-8.6 Phos-1.8* Mg-2.1 +[**2140-10-17**] 04:55AM BLOOD Calcium-9.3 Phos-3.1 Mg-1.8 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD CK(CPK)-97 +[**2140-10-12**] 03:22AM BLOOD CK(CPK)-90 +[**2140-10-12**] 10:26PM BLOOD CK(CPK)-102 + +LFTs: +[**2140-10-11**] 07:15PM BLOOD ALT-24 AST-38 CK(CPK)-92 AlkPhos-86 +Amylase-72 TotBili-0.3 + +Lipase: +[**2140-10-11**] 07:15PM BLOOD Lipase-35 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD cTropnT-0.01 +[**2140-10-12**] 03:22AM BLOOD CK-MB-NotDone cTropnT-0.02* +[**2140-10-12**] 10:26PM BLOOD CK-MB-4 cTropnT-0.01 + +Digoxin: +[**2140-10-11**] 12:45PM BLOOD Digoxin-0.4* + +ECG: Sinus rhythm with demand ventricular pacing +Ventricular premature complexes +Since previous tracing of the same date, QRS width shorter, +assess LV pacing + +CXR: FINDINGS: The pacer/defibrillator leads are again seen +terminating in the right ventricle and coronary sinus. There are +median sternotomy wires. An additional disconnected pacer wire +is seen within the left chest wall, as on prior. There is no +evidence of pneumonia. There is cardiomegaly, without CHF. There +is no pneumothorax or pleural effusion. Degenerative changes are +seen at the right humeral head. The bones are otherwise +unremarkable. +IMPRESSION: No acute intrathoracic process. Cardiomegaly without +CHF. + +ECHO: The left atrium is dilated. Left ventricular wall +thicknesses are normal. The left ventricular cavity is severely +dilated. There is severe regional left ventricular systolic +dysfunction with akinesis of all inferior and inferolateral +segments and of the basal lateral segments. The other segments +are severely hypokinetic. There is no ventricular septal defect. +The right ventricular cavity is mildly dilated with mild global +free wall hypokinesis. The aortic root is moderately dilated at +the sinus level. The aortic valve leaflets are severely +thickened/deformed. There is moderate to severe aortic valve +stenosis (area 0.8-1.0cm2). No aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Moderate (2+) mitral regurgitation is seen. +There is mild pulmonary artery systolic hypertension. There is +no pericardial effusion. +IMPRESSION: Severe focal and global LV systolic dysfunction. +Moderate to severe aortic stenosis. Moderate mitral +regurgitation. + +Abdominal XR: FOUR VIEWS OF THE ABDOMEN: There are moderately +dilated loops of small bowel, and multiple air-fluid levels are +demonstrated on the left lateral decubitus. There is no evidence +of free air. Cholecystectomy clips in the right upper quadrant +and the right hip arthroplasty are again identified. There is +air within the rectum. The left hip demonstrates moderate +degenerative change. Midline sternotomy wires and a pacing +device are identified. +IMPRESSION: Moderately dilated loops of small bowel and +air-fluid levels are consistent with ileus or early/partial +small-bowel obstruction. + + +Brief Hospital Course: +The patient was admitted to the MICU for monitoring and serial +Hcts. His BP reamined in the 90-110 systolic range. A Hct drop +from 39 to 32 was noted, which then stabilized. GI saw the +patient, no plan for emergent scope. Cardiology saw the pt and +recommended an echocardiogram. Cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. Diuretics and anti-hypertensives were held. +. + +A/P: 72 yo M with MMP including CAD, CHF, CRI admit with GIB, +abdominal pain, and chest pain, now callout from MICU. +. +# GI bleed/Abd pain: Hx GI bleeding in the past, recent EGD by +GI showed erosions in stomach and duodenum c/w NSAID +gastropathy, had a normal [**Last Name (un) **] in [**Month (only) 547**]. Hct stable and has not +required transfusion. No evidence of active bleed. LFTs normal +on admit. Mesenteric ischemia was considered as patient +stabalized this was not pursed. He had some persistent nausea +which improved with reglan. He was discharged in omeprazole. + +. +# Chest pain: with extensive CAD and CHF history. Echo done this +admit as above. He was ruled out for an MI. +. +# Systolic heart failure: Focal akinesia as above. He was +satting well on room air and did not have clinical evidence of +heart failure +. +# Afib: Medications were continued, coumadin was stopped. +. +# Chronic renal insufficiency: Baseline cr 1.6-2. Currently at +baseline. +. +# Hyperlipidemia: +- continue statin +. +# Hypothyroidism: +- continue levothyroxine +. +# Asthma: +- continue home meds +. +CODE: Full (confirmed with patient) +. +Communication: Pt, wife [**Doctor First Name **] [**Telephone/Fax (1) 30058**]) + + +Medications on Admission: +Sotalol 80mg [**Hospital1 **] +Lipitor 20mg daily +Donepezil 5mg daily +Quetiapine 25mg, 3tabs qAM, 1tab noon, 3tabs qHS +Celexa 60mg daily +Protonix 40mg daily +ASA 81mg daily +Clonazepam 0.5mg TID PRN +Lisinopril 5mg daily +Digoxin 125mcg, [**1-13**] tab daily +K-Dur daily +Spironolactone 25mg daily +Levothyroxin3e 112mcg daily +Trazodone 25mg qHS +Mexiletine 150mg TID +Albuterol MDI 2puf q6hPRN +Fluticasone 110mcg 2puff [**Hospital1 **] +Toprol SL 50mg daily +Lasix 40mg TID +Coumadin + + +Discharge Medications: +1. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +2. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Donepezil 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). + +4. Citalopram 40 mg Tablet Sig: 1.5 Tablets PO once a day. +5. Quetiapine 25 mg Tablet Sig: as directed Tablet PO three +times a day: take 2 tabs every morning, 1 tab at noontime, and 3 +tabs at bedtime. +6. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO three times a +day as needed for anxiety. +7. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +9. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +10. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime) as needed. +11. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +12. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed for shortness of breath or +wheezing. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation [**Hospital1 **] (2 times a day). +14. NitroQuick 0.4 mg Tablet, Sublingual Sig: One (1) +Sublingual as needed as needed for chest pain: as previously +directed, take up to 3 tabs five minutes apart. +15. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +16. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +17. Aspirin 81 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO DAILY (Daily). +18. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY +(Daily). +19. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +20. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times +a day) as needed for nausea. +Disp:*45 Tablet(s)* Refills:*2* +21. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +22. Furosemide 80 mg Tablet Sig: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Gastrointestinal bleeding +. +Congestive heart failure, systolic dysfunction, chronic +Coronary artery disease +Atrial fibrillation +Chronic kidney disease +Alzheimer's dementia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted with bleeding, likely from your stomach. We +think that this was in part related to taking coumadin and after +much discussion, we have stopped this medication. You blood +counts have been stable. +. +Please return to the hospital or call your doctor if you have +worsening abdominal pain, pain after eating, blood in your vomit +or stools, dark colored stools, chest pain, shortness of breath, +or any new symptoms that you are concerned about. +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +. +Since you were admitted we have made the following medication +changes: +* Please stop taking COUMADIN. +* Your lasix dose was increased to 80 mg daily. + +Followup Instructions: +Please call your primary care physician, [**Last Name (NamePattern4) **]. [**Last Name (STitle) 26894**], to schedule +a followup appointment within 2 weeks. +. +You also have the following upcoming appointments at [**Hospital1 18**]: +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 21795**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-4**] 1:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-25**] 8:40 +DEVICE CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2140-12-19**] 1:00 + + + +",12,2140-10-11 14:34:00,2140-10-18 15:38:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN;TELEMETRY;GI BLEED," +the patient was admitted to the micu for monitoring and serial +hcts. his bp reamined in the 90-110 systolic range. a hct drop +from 39 to 32 was noted, which then stabilized. gi saw the +patient, no plan for emergent scope. cardiology saw the pt and +recommended an echocardiogram. cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. diuretics and anti-hypertensives were held. +. + +a/p: 72 yo m with mmp including cad, chf, cri admit with gib, +abdominal pain, and chest pain, now callout from micu. +. +# gi bleed/abd pain: hx gi bleeding in the past, recent egd by +gi showed erosions in stomach and duodenum c/w nsaid +gastropathy, had a normal [**last name (un) **] in [**month (only) 547**]. hct stable and has not +required transfusion. no evidence of active bleed. lfts normal +on admit. mesenteric ischemia was considered as patient +stabalized this was not pursed. he had some persistent nausea +which improved with reglan. he was discharged in omeprazole. + +. +# chest pain: with extensive cad and chf history. echo done this +admit as above. he was ruled out for an mi. +. +# systolic heart failure: focal akinesia as above. he was +satting well on room air and did not have clinical evidence of +heart failure +. +# afib: medications were continued, coumadin was stopped. +. +# chronic renal insufficiency: baseline cr 1.6-2. currently at +baseline. +. +# hyperlipidemia: +- continue statin +. +# hypothyroidism: +- continue levothyroxine +. +# asthma: +- continue home meds +. +code: full (confirmed with patient) +. +communication: pt, wife [**doctor first name **] [**telephone/fax (1) 30058**]) + + + ","PRIMARY: [Hemorrhage of gastrointestinal tract, unspecified] +SECONDARY: [Acute on chronic systolic heart failure; Atrial fibrillation; Other and unspecified angina pectoris; Hypovolemia; Aortic valve disorders; Asthma, unspecified type, unspecified; Chronic kidney disease, unspecified; Aortocoronary bypass status; Long-term (current) use of anticoagulants; Automatic implantable cardiac defibrillator in situ; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Congestive heart failure, unspecified; Unspecified analgesic and antipyretic causing adverse effects in therapeutic use; Anticoagulants causing adverse effects in therapeutic use; Other specified forms of chronic ischemic heart disease; Other and unspecified hyperlipidemia; Barrett's esophagus; Diverticulosis of colon (without mention of hemorrhage); Unspecified acquired hypothyroidism]" +10774,197363.0,8555,2141-04-05,8554,173586.0,2141-03-30,Discharge summary,"Admission Date: [**2141-3-8**] Discharge Date: [**2141-3-30**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**Last Name (NamePattern1) 1167**] +Chief Complaint: +Chest pain and abdominal pain + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +This is a 73 year old male with past medical history significant +for CAD s/p CABG and PCI to LCx, aortic stenosis, VT/VF arrest +s/p ICD, CHF (EF 20%) s/p BiV pacer, afib on coumadin, CRI and +diverticulosis who presents with 1 hour of chest pain similar to +anginal equivalent that radiated to abd and back. Assocated with +nausea. Took ntg tab w/o relief. No pleuritic chest pain. The +abd pain is LLQ predominant w/o radiation. He states that he has +had black stools on both of the last 2 days associated with +changed smell of the stools. He has had no bloody stool. The abd +pain usually is better after eating. There have been no new +foods and no sick contacts. +. +Of note the patient was recently in the [**Hospital1 18**] for abdominal pain +in [**1-20**]. At which time his labs were unremarkable. A CT abd +showed no acute pathology to explain his pain. He received IV +fluids and slowly advanced his diet to normal prior to +discharge. +. +In ED, initial vitals were 97.8 120/70 100 14 100%RA. Stools +brown and OB negative. +ECG was V-paced at 85bpm, cardiac enzymes were negative. +Patient given aspirin, nitro tabs, morphine. +. +On floor, patient was with decreasing chest pain but still with +nausea. The abdominal pain is also improved. +. +On review of systems, he denies any prior history of stroke, +TIA, deep venous thrombosis, pulmonary embolism, bleeding at the +time of surgery, myalgias, joint pains, cough, hemoptysis, he +denies recent fevers, chills or rigors. he denies exertional +buttock or calf pain. his weight has been stable at +222-223pounds. His baseline function is 1 flight of stairs. All +of the other review of systems were negative. +. +Cardiac review of systems is notable for paroxysmal nocturnal +dyspnea, orthopnea, ankle edema, palpitations, syncope or +presyncope. +. + +Past Medical History: +CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] +s/p VT/VF arrest, s/p ICD placement in [**2135**] +iCMP (EF 20%) s/p BiV pacer [**10-18**] +Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +AFib (not anti-coagulated due to recurrent GI bleeds) +CKD Stage III b/l Cr. ~1.6 +Hyperlipidemia +Asthma +Anxiety +Alzheimer's dementia +Hypothyroidism +Diverticulosis +GERD +s/p cholecystectomy +. +CARDIAC RISK FACTORS: -Diabetes, +Dyslipidemia, +Hypertension + +Social History: +married, lives with wife. [**Name (NI) **] originally from [**Country 4754**]. No +history of smoking. Patient was a heavy drinker until 20 years +ago. No history of illicit drugs + +Family History: +No family history of early MI, otherwise non-contributory. + +Physical Exam: +On admission- +VS: 98.5 100/71 82 16 99%2L +wt. 222 lbs +GENERAL: WDWN obese male in NAD. Oriented x3. Mood, affect +appropriate. +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. No xanthalesma. +NECK: Supple with JVP of 8 cm. +CARDIAC: PMI laterally displaced. RR, normal S1, S2. [**2-17**] +systolic murmur at RUSB c/w AS. No r/g. No thrills, lifts. No S3 +or S4. +LUNGS: No chest wall deformities, scoliosis or kyphosis. Resp +were unlabored, no accessory muscle use. CTAB, no crackles, +wheezes or rhonchi. +ABDOMEN: Soft, minimal tender to LLSB. No HSM or tenderness. Abd +aorta not enlarged by palpation. No abdominal bruits. guiaiac +negative brown stool. +EXTREMITIES: No c/c/e. No femoral bruits. +SKIN: No stasis dermatitis, ulcers, scars, or xanthomas. +PULSES: +Right: Carotid 2+ Femoral 2+ Popliteal 2+ DP 1+ PT 1+ +Left: Carotid 2+ Femoral 2+ Popliteal 2+ DP 1+ PT 1+ +Neuro: +-MS alert and oriented x3. coherent response to interview +-CN II-XII intact +-Motor moving all 4 extremities symmetrically. +-[**Last Name (un) **] light touch intact to face/hands/feet + +Pertinent Results: +======== +Labs +======== + +[**2141-3-30**] 11:51AM BLOOD Hct-27.8* +[**2141-3-30**] 11:51AM BLOOD PT-22.2* PTT-91.8* INR(PT)-2.1* +[**2141-3-30**] 04:09AM BLOOD WBC-9.2 RBC-2.92* Hgb-8.4* Hct-26.2* +MCV-90 MCH-28.8 MCHC-32.1 RDW-15.5 Plt Ct-255 +[**2141-3-30**] 04:09AM BLOOD Glucose-193* UreaN-31* Creat-2.0* Na-132* +K-4.5 Cl-97 HCO3-27 AnGap-13 +[**2141-3-11**] 06:37AM BLOOD WBC-6.5 RBC-4.10* Hgb-11.9* Hct-35.6* +MCV-87 MCH-29.1 MCHC-33.5 RDW-14.6 Plt Ct-144* +[**2141-3-10**] 05:15AM BLOOD WBC-7.4 RBC-4.16* Hgb-12.2* Hct-35.8* +MCV-86 MCH-29.2 MCHC-34.0 RDW-14.7 Plt Ct-136* +[**2141-3-9**] 05:15AM BLOOD WBC-8.7 RBC-4.14* Hgb-12.3* Hct-35.7* +MCV-86 MCH-29.7 MCHC-34.5 RDW-14.5 Plt Ct-145* +[**2141-3-8**] 06:45PM BLOOD WBC-9.2 RBC-4.44* Hgb-13.0* Hct-38.5* +MCV-87 MCH-29.2 MCHC-33.7 RDW-14.5 Plt Ct-193 +[**2141-3-11**] 06:37AM BLOOD Glucose-86 UreaN-17 Creat-1.6* Na-140 +K-4.0 Cl-103 HCO3-27 AnGap-14 +[**2141-3-10**] 05:15AM BLOOD Glucose-72 UreaN-20 Creat-1.5* Na-138 +K-3.8 Cl-103 HCO3-27 AnGap-12 +[**2141-3-9**] 05:15AM BLOOD Glucose-86 UreaN-25* Creat-1.6* Na-140 +K-4.4 Cl-102 HCO3-29 AnGap-13 +[**2141-3-8**] 06:45PM BLOOD Glucose-95 UreaN-26* Creat-1.7* Na-138 +K-4.3 Cl-100 HCO3-31 AnGap-11 +[**2141-3-10**] 05:15AM BLOOD ALT-42* AST-47* AlkPhos-132* Amylase-112* +[**2141-3-9**] 05:15AM BLOOD LD(LDH)-276* CK(CPK)-86 Amylase-208* +[**2141-3-8**] 06:45PM BLOOD ALT-20 AST-30 CK(CPK)-96 AlkPhos-92 +Amylase-137* TotBili-0.3 +[**2141-3-11**] 06:37AM BLOOD Lipase-33 +[**2141-3-10**] 05:15AM BLOOD Lipase-46 +[**2141-3-9**] 04:05PM BLOOD Lipase-58 +[**2141-3-9**] 05:15AM BLOOD Lipase-164* +[**2141-3-8**] 06:45PM BLOOD Lipase-124* +[**2141-3-9**] 05:15AM BLOOD CK-MB-NotDone cTropnT-0.01 +[**2141-3-8**] 06:45PM BLOOD cTropnT-<0.01 +[**2141-3-8**] 06:45PM BLOOD Digoxin-0.7* +. +========= +Radiology +========= +CXR [**3-8**] +FINDINGS: PA and lateral views of the chest are obtained. +Three-lead pacer +device is unchanged with lead tips positioned in the expected +location. +Midline sternotomy wires are unchanged. Cardiomegaly is stable. +There is no +CHF or evidence of pneumonia. No pleural effusion or +pneumothorax is seen. +Osseous structures are intact. + +IMPRESSION: No significant change with persistent cardiomegaly +and no evidence +of CHF or pneumonia. +. +RUQ U/S [**3-9**] +RIGHT UPPER QUADRANT ULTRASOUND: The liver appears unremarkable +in +echotexture and architecture, without focal liver lesion seen. +Flow in the +main portal vein is in normal hepatopetal direction. No intra- +or extra- +hepatic biliary ductal dilatation is noted, with the common duct +measuring 5 +mm. Again the gallbladder is absent, consistent with prior +cholecystectomy. +Visualization of the pancreatic tail is slightly limited due to +overlying +bowel gas however the visualized pancreas appears unremarkable +and unchanged. +No pancreatic ductal dilatation is noted. No ascites is seen. +The spleen is +enlarged, measuring 13.8 cm. + +IMPRESSION: +1. Patient is status post cholecystectomy. No intra- or +extra-hepatic +biliary ductal dilatation is noted. No choledocholithiasis seen. +2. Incidentally noted splenomegaly. +. +=========== +Cardiology +=========== +TTE [**3-9**] + +Conclusions +The left atrium is moderately dilated. The right atrium is +moderately dilated. There is mild symmetric left ventricular +hypertrophy. The left ventricular cavity is severely dilated. +Overall left ventricular systolic function is severely depressed +(LVEF= 20 %). Tissue Doppler imaging suggests an increased left +ventricular filling pressure (PCWP>18mmHg). There is no +ventricular septal defect. Right ventricular chamber size is +normal. with borderline normal free wall function. with focal +hypokinesis of the apical free wall. The aortic root is mildly +dilated at the sinus level. There are focal calcifications in +the aortic arch. The number of aortic valve leaflets cannot be +determined. The aortic valve leaflets are severely +thickened/deformed. There is moderate to severe aortic valve +stenosis (area 0.8-1.0cm2). No aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Moderate (2+) mitral regurgitation is seen. The +tricuspid valve leaflets are mildly thickened. There is moderate +pulmonary artery systolic hypertension. The main pulmonary +artery is dilated. The branch pulmonary arteries are dilated. + +Compared with the findings of the prior study (images reviewed) +of [**2140-10-12**], no major change is evident. +. +Myocardial perfusion study [**3-11**] +IMPRESSION: 1) Severe left ventricular enlargment 2) Probably +some viability within an inferior wall defect. + +TTE [**2141-3-14**] The left ventricular cavity is dilated. Due to +suboptimal technical quality, a focal wall motion abnormality +cannot be fully excluded. Overall left ventricular systolic +function is severely depressed (LVEF= 20 %). The right +ventricular cavity is mildly dilated with normal free wall +contractility. The aortic valve leaflets are mildly thickened. +The mitral valve leaflets are mildly thickened. Mild to moderate +([**1-13**]+) mitral regurgitation is seen. There is no pericardial +effusion. +IMPRESSION: Suboptimal image quality. Focused views. Severe left +ventricular sysolic dysfunction. Mild to moderate mitral +regurgitation. +Compared with the prior study (images reviewed) of [**2141-3-9**], +this is a limited/emergent/focused study and direct comparison +cannot be made. + +Cardiac Cath [**2141-3-20**] +COMMENTS: +1. Coronary angiography of this right dominant system +demonstrated no +angiographically apparent flow-limiting coronary artery disease. + +2. Non-selective arteriography of the LIMA-LAD showed no +apparent +flow-limiting disease. +3. Limited resting hemodynamics revealed a central aortic +pressure of +134/92 mmHg. + +FINAL DIAGNOSIS: +1. No angiographically apparent flow-limiting coronary artery +disease. +2. Patent LIMA-LAD. + +[**2141-3-26**] LEFT UPPER EXTREMITY VENOUS ULTRASOUND: [**Doctor Last Name **]-scale and +color and pulsed wave Doppler examination was performed over the +right subclavian vein as well as the left internal jugular, +subclavian, axillary, brachial, basilic, and cephalic veins. +Note is made of nearly occlusive thrombosis of the left +cephalic, basilic, brachial, and axillary veins. Flow is +demonstrated in the left and right subclavian veins. More +proximally, note is made of likely pacemaker wire entering the +left subclavian vein. The internal jugular vein demonstrates +normal compressibility and flow. +IMPRESSION: Left upper extremity DVT extending from the +superficial cephalic and basilic veins into the brachial and +axillary deep veins. + +CXRs: +[**2141-3-28**] PORTABLE SEMI-UPRIGHT RADIOGRAPH OF THE CHEST: The +distal tip of right PICC projects in the mid SVC. There has been +interval removal of the endotracheal tube and NG tube. The +remainder of the study including the position of the AICD leads +and the cardiopulmonary status appear unchanged. +IMPRESSION: Standard position of the right PICC with no +complication. + +Pertinent Micro data +[**2141-3-22**] 2:00 pm URINE Source: Catheter. + + **FINAL REPORT [**2141-3-24**]** + + URINE CULTURE (Final [**2141-3-24**]): + ESCHERICHIA COLI. 10,000-100,000 ORGANISMS/ML.. + PRESUMPTIVE IDENTIFICATION. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ESCHERICHIA COLI + | +AMPICILLIN------------ =>32 R +AMPICILLIN/SULBACTAM-- 4 S +CEFAZOLIN------------- <=4 S +CEFEPIME-------------- <=1 S +CEFTAZIDIME----------- <=1 S +CEFTRIAXONE----------- <=1 S +CEFUROXIME------------ <=1 S +CIPROFLOXACIN---------<=0.25 S +GENTAMICIN------------ <=1 S +MEROPENEM-------------<=0.25 S +NITROFURANTOIN-------- <=16 S +PIPERACILLIN/TAZO----- <=4 S +TOBRAMYCIN------------ <=1 S +TRIMETHOPRIM/SULFA---- <=1 S + +GRAM STAIN (Final [**2141-3-21**]): + >25 PMNs and <10 epithelial cells/100X field. + 2+ (1-5 per 1000X FIELD): GRAM POSITIVE COCCI. + IN PAIRS, CHAINS, AND +CLUSTERS. + 1+ (<1 per 1000X FIELD): GRAM POSITIVE ROD(S). + + RESPIRATORY CULTURE (Final [**2141-3-24**]): + MODERATE GROWTH OROPHARYNGEAL FLORA. + STAPH AUREUS COAG +. MODERATE GROWTH. + Oxacillin RESISTANT Staphylococci MUST be reported as +also + RESISTANT to other penicillins, cephalosporins, +carbacephems, + carbapenems, and beta-lactamase inhibitor combinations. + + Rifampin should not be used alone for therapy. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + STAPH AUREUS COAG + + | +CLINDAMYCIN----------- =>8 R +ERYTHROMYCIN---------- =>8 R +GENTAMICIN------------ <=0.5 S +LEVOFLOXACIN---------- =>8 R +OXACILLIN------------- =>4 R +RIFAMPIN-------------- <=0.5 S +TETRACYCLINE---------- 2 S +TRIMETHOPRIM/SULFA---- <=0.5 S +VANCOMYCIN------------ <=1 S + +C diff negative +Blood cx ngtd + +Brief Hospital Course: +# VT: Initially on home meds of mexilitine and sotalol. On the +floor, had an episode VT on telemetry and lost pulses. He +[**Month/Day/Year 1834**] CPR, receiving a total of 4 shocks, 4mg of +epinephrine, amiodarone 150mg x 2, Lidocaine 100mg x 1, +magnesium 2mg, bicarb 1 amp, and calcium. Pacer interrogation +showed his VT was below the rate of detection. He was manually +paced out of VT several times but with return to VT each time. +Finally, lidocaine and amiodarone gtts were started and the +patient was successfully converted back to a paced rhythm. His +mexilitine and sotalol were held. He was intubated during the +code, but rapidly extubated afterward. From [**3-15**] to [**3-21**], he had +repeated episodes of VT, receiving multiple ICD shocks each +time, with conversion to a paced rhythm. The first of these +episodes was associated with hypotension, but subsequent +episodes showed good BP. He was given ativan for sedation due to +the multiple shocks, and was reintubated [**3-19**] for airway +protection from sedation. Over the course of these several +episodes, he received multiple amiodarone and lidocaine boluses, +and was variably on and off drips of these medications. On [**3-21**], +he had an EP study and had 1 circuit ablated and an epicardial +circuit interrupted. He was transitioned to a final regimen of +oral mexilitene alone. After the study, he was kept sedated and +initially required phenylephrine and vasopressin. He had +multiple VT episodes on [**3-22**], but successfully paced out without +shocks. He was weaned off pressors and extubated, and +subsequently started on metoprolol, which was uptitrated to 25mg +TID. His only further VT was on [**3-28**], and he was successsfully +paced out. EP recommends that he continue on telemetry +monitoring for 48 hours after discharge. + +# Chest pain: Has a history of CAD, although cardiac cath done +during admission was clean and biomarkers on admission for chest +pain in the ER were negative. After CPR, patient had significant +reproducible chest wall tenderness that was due to the direct +trauma of chest compressions. This pain was not felt to be +ischemia. He was treated initially with IV morphine and +hydromorphone, but received better pain control after +transitioning to oral MS contin. He is also on [**Month/Year (2) 1988**] tylenol +and a lidocaine patch. + +# Anxiety: Patient has known anxiety, and this was significantly +worsened in the setting of recurrent VT and receiving many ICD +shocks. Psychiatry was consulted and advised seroquel PRN in +addition to his standing doses. He was also continued on +citalopram and low dose clonazepam. Despite this, he continued +to have significant anxiety; he would have episodes of +lightheadedness and palpitations, despite normal vital signs and +no telemetry changes. Also, he at times thought his ICD had +fired, but review of telemetry showed this was not the case. He +also becomes diaphoretic, but per patient and wife, this is +long-standing and his baseline. + +# Abdominal pain: Presented with nausea, vomiting, abdominal +pain and elevated lipase, otherwise normal LFTs. No cholethiasis +on abdominal u/s. He was ruled out for acute cardiac event. He +was treated with bowel rest and his diet was slowly advanced as +tolerated. + +# DVT: LUE had swelling and ultrasound was positive. He was +started on a heparin drip and bridged to warfarin before +discharge. Continued on PPI and sucralfate given history of GI +bleeds and ASA was lowered from 325mg to 81mg daily. He will +need a follow up ultrasound in [**3-15**] mos. + +# Pump: LVEF 20% on TTE [**10-19**]. Also has known AS, although +during admission patient was refusing AVR and valvuloplasty. He +became hypervolemic around [**3-18**], requiring a lasix gtt. His +volume status improved and he was transitioned to his home dose +of lasix 40mg PO daily. His digoxin was stopped due to +arrhythmogenic concerns. Beta blocker continued as above. +Spironolactone was increased from 12.5 to 25mg daily. + +# CKD: Baseline Cr around 1.6. Prior to discharge, his +creatinine trended up to 2.0 in the setting of increased ACE-I +and restarting furosemide. Per discussion with his outpatient +cardiologist, this is acceptable for now and can be followed +after discharge, with med changes made as needed. + +# MRSA Pneumonia: Pt developed MRSA pneumonia with sputum +growing MRSA. He was treated with Vancomycin 8 day course which +he completed on [**2141-3-29**] + +# UTI: Pt had E coli UTI. He was initially on pip-tazo for +empiric pneumonia coverage, but changed to ceftriaxone once +sensitivities returned. He completed a 7 day course of +antibiotics. + +# CODE: Code status had been changed to 1 externmal shock if +neccessary but no compressions. This was reversed on [**2141-3-28**] +when patient expressed desire to be full code. + +Medications on Admission: +Sotalol 80 mg [**Hospital1 **] +Levothyroxine 112 mcg daily +Citalopram 60 mg daily +Quetiapine 50 mg QAM +Quetiapine 25 mg daily at noon +Quetiapine 75 mg QHS +Sucralfate 1 gram QID +Mexiletine 150 mg Q8H +Pantoprazole 40 mg Q12 +Atorvastatin 20 mg daily +Fluticasone-Salmeterol 250-50 mc 2 puffs [**Hospital1 **] +Donepezil 5 mg QHS +Metoprolol Succinate 50 mg QHS +Furosemide 40 mg daily +Spironolactone 12.5 mg daily +Nitroglycerin 0.3 mg PRN (as needed) as needed for chest pain. +Clonazepam 0.5 mg TID (3 times a day) as needed for anxiety. +Trazodone 50 mg qhs:prn insomnia +Metoclopramide 25 mg q8 prn +Digoxin 0.0625 mcg daily +Albuterol 90 mcg prn +Aspirin 81 mg daily +K-Dur 20 mEq daily +. + +Discharge Medications: +1. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Citalopram 20 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +3. Donepezil 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). + +4. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +6. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +7. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +8. Metoclopramide 10 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) as needed. +9. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +at noon. +10. Quetiapine 25 mg Tablet Sig: Two (2) Tablet PO QAM (once a +day (in the morning)). +11. Quetiapine 25 mg Tablet Sig: Three (3) Tablet PO HS (at +bedtime). +12. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +13. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO QID (4 times +a day). +14. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day: Hold for loose stools. +15. Spironolactone 25 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +16. Loperamide 2 mg Capsule Sig: One (1) Capsule PO QID (4 times +a day) as needed. +17. Quetiapine 25 mg Tablet Sig: 0.5 Tablet PO BID (2 times a +day) as needed for anxiety. +18. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +19. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +20. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +21. Acetaminophen 500 mg Tablet Sig: Two (2) Tablet PO four +times a day. +22. Heparin Flush (10 units/ml) 2 mL IV PRN line flush +PICC, heparin dependent: Flush with 10mL Normal Saline followed +by Heparin as above daily and PRN per lumen. +23. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +Hold SBP< 90. +24. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +25. Sodium Chloride 0.9% Flush 10 mL IV PRN line flush +Temporary Central Access-ICU: Flush with 10mL Normal Saline +daily and PRN. +26. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +27. FerrouSul 325 mg (65 mg Iron) Tablet Sig: One (1) Tablet PO +once a day. +28. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +29. Morphine 15 mg Tablet Sustained Release Sig: [**1-13**] Tablet +Sustained Releases PO every eight (8) hours as needed for chest +pain. +30. Digoxin 125 mcg Tablet Sig: 0.5 Tablet PO once a day. +31. Warfarin 5 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: check INR on [**2141-4-1**]. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 105**] - [**Location (un) 86**] + +Discharge Diagnosis: +Primary: Pancreatitis, Ventricular Tachycardia, Hypotension, +Pneumonia +Secondary: Aortic stenosis, Coronary artery disease + + +Discharge Condition: +stable, tolerating oral intake + + +Discharge Instructions: +You presented to the hospital with chest pain and abdominal +pain. There was some initial concern that you were having a +heart attack, but this was ruled out by basic lab work. Your +chest pain resolved in the emergency room and you were chest +pain free on the cardiology floor. It was recommended that you +consider valvuloplasy and angioplasty for your tight aortic +valve in your heart and your blocked blood vessels in your +heart, but you refused this intervention. Your abdominal pain +was felt to be due to inflammation in the pancreas. An +ultrasound of your abdomen did not reveal any stones as the +cause of this inflammation. Your pancreas improved with gently +hydration. While you were in the hospital, you also developed +worsening of your abnormal heart rhythm, requiring many shocks +by your ICD. You were kept sedated and with a breathing tube +since the shocks were so uncomfortable. You [**Location (un) 1834**] a +procedure to help improve your heart rhythm, and this helped +your heart rhythm considerably. You also developed pneumonia +while you were in the hospital, and we are treating you with +antibiotics. We have made several medication changes as listed +below. +. +We made the following changes to your medications: +- sotalol - we discontinued this medication +- trazodone - we discontinued this medication +- spironolactone - we increased this medication from 12.5mg once +a day to 25mg daily. +- reglan - we have decreased this medication from 25mg three +times a day as you need it to 10mg three times a day as you need +it. +- magnesium repletion as given at home. +-your Toprol was changed to short acting metoprolol +-your fluticasone was changed to Advair. +-we started tylenol around the clock, a lidoderm patch and long +acting morphine to treat your chest pain caused by rib +fractures. +-Warfarin to treat the clot in your left arm +. +Please seek immediate medical attention if you experience +worsening shortness of breath, abdominal pain, dizziness, bloody +bowel movements, black tarry bowel movements or any other change +from your baseline health status. + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +of 6 pounds in 3 days +Adhere to 2 gm sodium diet +Fluid Restriction: + +Followup Instructions: +Gastroenterology: +Please follow up with Dr. [**Last Name (STitle) 3708**] on [**4-7**] at 12:30pm. [**Hospital Ward Name 452**] 1, +[**Location (un) **], [**Hospital Ward Name 516**] entrance, [**Hospital1 18**]. If you need to +change this appointment please call [**Telephone/Fax (1) 463**]. +. +Cardiology: +Dr. [**First Name8 (NamePattern2) 449**] [**Last Name (NamePattern1) 437**] Phone: ([**Telephone/Fax (1) 2037**]. Date/Time: [**Telephone/Fax (1) 766**] [**4-3**] at 1:00 pm. [**Hospital Ward Name 23**] Building, [**Location (un) 436**] [**Hospital Ward Name 516**], [**Hospital1 18**] +. +Primary care: +Pleaes call your primary care doctor [**First Name (Titles) **] [**Last Name (Titles) **] an appointment +after you leave the rehabilitation facility to discuss this +hospital stay + + + +Completed by:[**2141-3-30**]",6,2141-03-08 23:26:00,2141-03-30 13:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,CHEST PAIN," +# vt: initially on home meds of mexilitine and sotalol. on the +floor, had an episode vt on telemetry and lost pulses. he +[**month/day/year 1834**] cpr, receiving a total of 4 shocks, 4mg of +epinephrine, amiodarone 150mg x 2, lidocaine 100mg x 1, +magnesium 2mg, bicarb 1 amp, and calcium. pacer interrogation +showed his vt was below the rate of detection. he was manually +paced out of vt several times but with return to vt each time. +finally, lidocaine and amiodarone gtts were started and the +patient was successfully converted back to a paced rhythm. his +mexilitine and sotalol were held. he was intubated during the +code, but rapidly extubated afterward. from [**3-15**] to [**3-21**], he had +repeated episodes of vt, receiving multiple icd shocks each +time, with conversion to a paced rhythm. the first of these +episodes was associated with hypotension, but subsequent +episodes showed good bp. he was given ativan for sedation due to +the multiple shocks, and was reintubated [**3-19**] for airway +protection from sedation. over the course of these several +episodes, he received multiple amiodarone and lidocaine boluses, +and was variably on and off drips of these medications. on [**3-21**], +he had an ep study and had 1 circuit ablated and an epicardial +circuit interrupted. he was transitioned to a final regimen of +oral mexilitene alone. after the study, he was kept sedated and +initially required phenylephrine and vasopressin. he had +multiple vt episodes on [**3-22**], but successfully paced out without +shocks. he was weaned off pressors and extubated, and +subsequently started on metoprolol, which was uptitrated to 25mg +tid. his only further vt was on [**3-28**], and he was successsfully +paced out. ep recommends that he continue on telemetry +monitoring for 48 hours after discharge. + +# chest pain: has a history of cad, although cardiac cath done +during admission was clean and biomarkers on admission for chest +pain in the er were negative. after cpr, patient had significant +reproducible chest wall tenderness that was due to the direct +trauma of chest compressions. this pain was not felt to be +ischemia. he was treated initially with iv morphine and +hydromorphone, but received better pain control after +transitioning to oral ms contin. he is also on [**month/year (2) 1988**] tylenol +and a lidocaine patch. + +# anxiety: patient has known anxiety, and this was significantly +worsened in the setting of recurrent vt and receiving many icd +shocks. psychiatry was consulted and advised seroquel prn in +addition to his standing doses. he was also continued on +citalopram and low dose clonazepam. despite this, he continued +to have significant anxiety; he would have episodes of +lightheadedness and palpitations, despite normal vital signs and +no telemetry changes. also, he at times thought his icd had +fired, but review of telemetry showed this was not the case. he +also becomes diaphoretic, but per patient and wife, this is +long-standing and his baseline. + +# abdominal pain: presented with nausea, vomiting, abdominal +pain and elevated lipase, otherwise normal lfts. no cholethiasis +on abdominal u/s. he was ruled out for acute cardiac event. he +was treated with bowel rest and his diet was slowly advanced as +tolerated. + +# dvt: lue had swelling and ultrasound was positive. he was +started on a heparin drip and bridged to warfarin before +discharge. continued on ppi and sucralfate given history of gi +bleeds and asa was lowered from 325mg to 81mg daily. he will +need a follow up ultrasound in [**3-15**] mos. + +# pump: lvef 20% on tte [**10-19**]. also has known as, although +during admission patient was refusing avr and valvuloplasty. he +became hypervolemic around [**3-18**], requiring a lasix gtt. his +volume status improved and he was transitioned to his home dose +of lasix 40mg po daily. his digoxin was stopped due to +arrhythmogenic concerns. beta blocker continued as above. +spironolactone was increased from 12.5 to 25mg daily. + +# ckd: baseline cr around 1.6. prior to discharge, his +creatinine trended up to 2.0 in the setting of increased ace-i +and restarting furosemide. per discussion with his outpatient +cardiologist, this is acceptable for now and can be followed +after discharge, with med changes made as needed. + +# mrsa pneumonia: pt developed mrsa pneumonia with sputum +growing mrsa. he was treated with vancomycin 8 day course which +he completed on [**2141-3-29**] + +# uti: pt had e coli uti. he was initially on pip-tazo for +empiric pneumonia coverage, but changed to ceftriaxone once +sensitivities returned. he completed a 7 day course of +antibiotics. + +# code: code status had been changed to 1 externmal shock if +neccessary but no compressions. this was reversed on [**2141-3-28**] +when patient expressed desire to be full code. + + ","PRIMARY: [Acute pancreatitis] +SECONDARY: [Cardiac arrest; Paroxysmal ventricular tachycardia; Chronic systolic heart failure; Methicillin resistant pneumonia due to Staphylococcus aureus; Urinary tract infection, site not specified; ; Acute kidney failure with lesion of tubular necrosis; Ventricular fibrillation; Congestive heart failure, unspecified; Aortic valve disorders; Other specified forms of chronic ischemic heart disease; Atrial fibrillation; Long-term (current) use of anticoagulants; Asthma, unspecified type, unspecified; Other and unspecified hyperlipidemia; Chronic kidney disease, Stage III (moderate); Aortocoronary bypass status; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Unspecified acquired hypothyroidism; Diverticulosis of colon (without mention of hemorrhage); ; Fitting and adjustment of automatic implantable cardiac defibrillator]" +10774,197363.0,8555,2141-04-05,8553,142104.0,2140-10-30,Discharge summary,"Admission Date: [**2140-10-23**] Discharge Date: [**2140-10-30**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 905**] +Chief Complaint: +melena + +Major Surgical or Invasive Procedure: +Esophagogastroduodenoscopy [**2140-10-26**] +Esophagogastroduodenoscopy [**2140-10-27**] + + +History of Present Illness: +72 yo M with PMH of CAD s/p CABG and PCI to LCx, AS, VT/VF +arrest with BiV pacer, CHF (EF 20%), afib on coumadin, CRI (BL +Cr 1.6-2), and diverticulosis admitted with abdominal pain and +melena for two days. Reported hypotension by VNA to 96/P. The +patient has a history of recurrent GIB with most recent +admission on [**2140-10-11**] to [**10-18**]. During last hospital stay the +patient was admitted to the MICU for monitoring and serial Hcts. +A Hct drop from 39 to 32 was noted, which then stabilized. GI +saw the patient and deferred scope. His coumadin was +discontinued at this time due to recurrent bleeding. He was also +admitted on [**9-12**] with melena and abd pain. EGD showed Barrett's +esophagitis, gastritis, and duodenitis. He has a history of +polyp removal in the cecum and one in the ascending colon in +[**4-19**], histology was adenomatous. He also had a capsule study at +that time, that did not show additional source of bleed in the +small bowel. + +In ED, Vitals T 98.2, HR 78, BP 111/61, RR 18, 100% 2L NC. NG +lavage showed scant blood initially which cleared with lavage. +HCT stable. He was given morphine 4mg X3. No ASA given. Bolused +with 40mg IV pantoprazole X1. + +On arrival to MICU, pt is in no acute distress. Reports [**5-17**] +black, tarry stools last pm with associated dizziness. Pt has +also had ongoing abdominal and back pain since discharge last +week. His pain is constant and non-radiating located in his +chest, abdomen and back. + +Past Medical History: +CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +s/p VT/VF arrest, s/p ICD placement in [**2135**] +iCMP (EF 20%) s/p BiV pacer [**10-18**] +Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +AFib +CKD Stage III b/l Cr. ~1.6 +Hyperlipidemia +Asthma +Anxiety +Alzheimer's dementia +Hypothyroidism +Diverticulosis +GERD +s/p CCY + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Father of five children. No history of smoking. +Patient was a heavy drinker until 20 years ago, when he stopped +completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + +Family History: +Non-contributory + +Physical Exam: +DISCHARGE PHYSICAL EXAM +V/S: 99.1, 97.6, 120/70-102/62, 80s, 16, 94% RA +GEN - Obese gentleman appears comfortable, NAD +HEENT- sclera anicteric, OP clear with MMM +NECK: supple without JVD, delayed carotid upstroke no bruit +CV: reg rate nl S1 no S2 III/VI SEM at LUSB +PULM: CTAB no w/r/r +ABD: soft NTND normoactive BS no organomegaly +EXT- warm, dry diminished distal pulses no c/c/e +NEURO: A&Ox3 + +Pertinent Results: +[**2140-10-30**] 08:20AM BLOOD WBC-7.0 RBC-3.95* Hgb-11.7* Hct-34.5* +MCV-87 MCH-29.5 MCHC-33.8 RDW-14.2 Plt Ct-198 +[**2140-10-29**] 08:10AM BLOOD WBC-5.6 RBC-3.82* Hgb-11.2* Hct-33.2* +MCV-87 MCH-29.4 MCHC-33.7 RDW-14.7 Plt Ct-186 +[**2140-10-28**] 07:35AM BLOOD WBC-5.8 RBC-3.60* Hgb-10.5* Hct-31.5* +MCV-88 MCH-29.1 MCHC-33.2 RDW-14.2 Plt Ct-167 +[**2140-10-27**] 07:00AM BLOOD WBC-6.5 RBC-3.66* Hgb-10.7* Hct-32.0* +MCV-87 MCH-29.1 MCHC-33.4 RDW-14.3 Plt Ct-160 +[**2140-10-26**] 06:10AM BLOOD WBC-12.4* RBC-4.01* Hgb-12.0* Hct-34.6* +MCV-86 MCH-29.9 MCHC-34.6 RDW-14.5 Plt Ct-164 +[**2140-10-25**] 06:00AM BLOOD WBC-9.0 RBC-4.04* Hgb-11.5* Hct-35.4* +MCV-88 MCH-28.5 MCHC-32.6 RDW-14.5 Plt Ct-176 +[**2140-10-24**] 07:52PM BLOOD Hct-34.6* +[**2140-10-24**] 04:57PM BLOOD Hct-33.4* +[**2140-10-24**] 06:55AM BLOOD WBC-7.9 RBC-4.09* Hgb-12.1* Hct-35.6* +MCV-87 MCH-29.5 MCHC-33.9 RDW-14.9 Plt Ct-181 +[**2140-10-24**] 01:05AM BLOOD Hct-34.5* +[**2140-10-23**] 06:45PM BLOOD WBC-10.1 RBC-4.03* Hgb-11.8* Hct-35.0* +MCV-87 MCH-29.2 MCHC-33.6 RDW-14.4 Plt Ct-175 +[**2140-10-23**] 12:58PM BLOOD WBC-7.7 RBC-4.21* Hgb-12.1* Hct-36.1* +MCV-86 MCH-28.8 MCHC-33.6 RDW-15.0 Plt Ct-169 +[**2140-10-28**] 07:35AM BLOOD ALT-18 AST-20 AlkPhos-86 TotBili-0.2 +[**2140-10-24**] 08:19AM BLOOD CK(CPK)-103 +[**2140-10-24**] 01:05AM BLOOD CK(CPK)-124 +[**2140-10-23**] 12:58PM BLOOD CK(CPK)-189* +[**2140-10-24**] 08:19AM BLOOD CK-MB-3 cTropnT-0.01 +[**2140-10-23**] 12:58PM BLOOD cTropnT-0.01 +[**2140-10-24**] 08:14PM BLOOD Lactate-0.9 +. +[**2140-10-26**] 12:52 pm STOOL CONSISTENCY: NOT APPLICABLE + Source: Stool. + + **FINAL REPORT [**2140-10-27**]** + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2140-10-27**]): + REPORTED BY PHONE TO [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) 30063**] @ 3:55A [**2140-10-27**]. + CLOSTRIDIUM DIFFICILE. + FECES POSITIVE FOR C. DIFFICILE TOXIN BY EIA. +. +[**2140-10-25**] CT OF THE ABDOMEN WITH IV CONTRAST: +Within the visualized lung bases, there is atelectasis within +the left lung base. There is no pleural effusion. Visualized +heart and pericardium reveal no pericardial effusion. +The liver, spleen, pancreas, and adrenal glands are +unremarkable. Multiple +rounded hypodensities in bilateral kidneys are stable, likely +reflecting renal cysts. Patient is status post cholecystectomy. +The stomach and small bowel are unremarkable. There is +diverticulosis of the colon, without evidence of diverticulitis. +There is no evidence of acute inflammation, or secondary signs +to suggest +mesenteric ischemia. Evaluation of the intra-abdominal +vasculature reveals +moderate diffuse atherosclerotic calcification involving the +abdominal aorta, not significantly changed from prior study. +There is mild atherosclerosis at the origin of the celiac axis. +Otherwise, celiac axis, superior mesenteric artery, and inferior +mesenteric artery and their branches appear patent and +unremarkable. +There is no free air, free fluid, or pathologic adenopathy. + +CT OF THE PELVIS WITH IV CONTRAST: Urinary bladder, rectum, and +prostate are unremarkable. There is no pelvic lymphadenopathy or +free fluid. + +OSSEOUS STRUCTURES: Patient status post total right hip +replacement. No +suspicious lytic or sclerotic lesions identified. + +IMPRESSION: No acute intra-abdominal process identified. The +celiac axis, +SMA, and [**Female First Name (un) 899**] appear patent without thrombosis or occlusion. No +secondary +signs to suggest mesenteric ischemia identified. +. +[**2140-10-26**] L-SPINE (AP & LAT) +FINDINGS: There is a levocurvature of the mid lumbar spine. +Multilevel +anterior osteophytes are noted. The disc spaces appear largely +preserved +aside from the scoliosis. Extensive vascular calcifications are +noted. There is a right hip total arthroplasty, partially +visualized. + +IMPRESSION: Multilevel degenerative changes as detailed. +. +[**2140-10-26**] Gastric mucosal biopsies +A. Body: Focal active gastritis; [**Doctor Last Name 6311**] stain shows no +definite helicobacter-like organisms with satisfactory control. +B. Antrum: No diagnostic abnormalities recognized. + +Brief Hospital Course: +#Acute gastritis - The patient was admitted to the ICU overnight +for observation given reported hypotension prior to admission. +Blood pressure was readily fluid-responsive and the patient +remained hemodynamically stable. Melena resolved after admission +and hematocrit remained stable, obviating the need for blood +transfusion. He was treated with PPI gtt in the ICU which was +changed to PPI [**Hospital1 **] on the floor. The patient [**Hospital1 1834**] EGD +showing erosive gastritis and Barrett's esophagus but no active +bleeding. Continued to hold coumadin. Aspirin was restarted in +the setting of [**Hospital1 **] PPI and carafate therapy which will be +continued after discharge at the recommendation of the +consulting GI team. He will follow up in [**Hospital **] clinic, in part to +schedule surveillance endoscopy for the monitoring of Barrett's. + +. +#Candidal esophagitis - EGD also revealed candidal esophagitis +which had been present on endoscopy 6 months prior and perhaps +inadequately treated with a 10-day course of fluconazole. HIV Ab +test was negative at that time. A 3-week course of oral +fluconazole was started with LFT's to be rechecked 1 week after +discharge. He was counseled regarding the proper use of his +corticosteroid inhalers including rinsing thoroughly after use. +. +#C. difficile colitis - The patient was started on a 2 week +course of flagyl. He was placed on contact precautions. [**Name2 (NI) **] was +counseled not to drink alcohol while taking metronidazole. +. +#Abdominal/back pain - This pain reportedly had been present for +several years but had subacutely worsened over the past [**6-23**] +months. Paraspinal muscle tenderness on examination was +suggestive of musculoskeletal pathology. CTA abd/pelvis showed +sigmoid diverticulosis but no evidence of mesenteric ischemia or +AAA. Lumbar plain film showed only chronic degenerative changes +but no compression deformity or lytic lesion. Stable hematocrit +made a RP bleed unlikely. Urinalysis, LFT's, calcium, and +SPEP/UPEP were normal. Pain was well-controlled with tylenol. +. +#Chronic systolic CHF - The patient appeared euvolemic without +signs or symptoms of acute CHF. ACEi had been discontinued prior +to admission due to hypotension. He will continue on +beta-blocker, digoxin, and diuretic therapy after discharge. +. +#Atrial fibrillation - Coumadin was held due to recurrent UGIB, +as above. Aspirin was continued. He was encouraged to follow up +with his cardiologist as soon as possible. +. +#Chronic kidney disease stage III - Creatinine remained at +baseline. Medications were dosed accordingly. +. +#Hyperlipidemia - Continued statin. +. +#Hypothyroidism - Continued levothyroxine. +. +#Asthma - Continued home regimen with counseling regarding +proper use of steroid inhalers, as above. +. +#Nutrition - Heart-healthy diet. +. +#Propylaxis - Pneumoboots, PPI + +Medications on Admission: +Sotalol 80 mg PO BID +Atorvastatin 20 mg PO DAILY +Donepezil 5 mg PO HS +Citalopram 40 mg 1.5 Tab PO DAILY +Quetiapine 25 mg Tab PO TID +Clonazepam 0.5 mg Tablet 1 Tablet PO TID PRN anxiety +Digoxin 62.5 mcg PO DAILY +K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal 1 Tab PO daily +Levothyroxine 112 mcg Tablet 1 Tablet PO DAILY +Trazodone 50 mg Tablet 1 PO HS +Mexiletine 150 mg Capsule 1 Capsule PO Q8H +Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H +Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation [**Hospital1 **] +NitroQuick 0.4 mg Tablet, Sublingual Sig: One (1) Sublingual as +needed as needed for chest pain +Magnesium Oxide 400 mg Tablet 1 Tablet PO daily +Pantoprazole 40 mg Tablet 1 tab Q 12 +Aspirin 81 mg Tablet PO DAILY +Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY +Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] +Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO TID/PRN nausea +Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr po +daily +Furosemide 80 mg Tablet PO daily + +Discharge Medications: +1. Fluconazole 100 mg Tablet Sig: One (1) Tablet PO Q24H (every +24 hours) for 11 days: Through Wednesday, [**11-9**]. +Disp:*11 Tablet(s)* Refills:*0* +2. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 11 days: Through Wednesday, [**11-9**]. +Disp:*33 Tablet(s)* Refills:*0* +3. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Citalopram 40 mg Tablet Sig: 1.5 Tablets PO once a day. +6. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at bedtime) +as needed for insomnia. +7. Quetiapine 25 mg Tablet Sig: Two (2) Tablet PO QAM (once a +day (in the morning)). +8. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO NOON (At +Noon). +9. Quetiapine 25 mg Tablet Sig: Three (3) Tablet PO HS (at +bedtime). +10. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO QID (4 times +a day). +Disp:*120 Tablet(s)* Refills:*0* +11. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +13. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +14. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) INH Inhalation [**Hospital1 **] (2 times a day). +15. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +every 4-6 hours as needed for shortness of breath or wheezing. +16. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 +hours) as needed for nausea. +17. Klonopin 0.5 mg Tablet Sig: One (1) Tablet PO three times a +day as needed for anxiety. +18. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +19. Aspirin EC 81 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO once a day. +20. Donepezil 5 mg Tablet Sig: One (1) Tablet PO at bedtime. +21. Toprol XL 50 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO at bedtime. +22. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +23. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +24. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +25. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +26. GlycoLax 17 gram (100 %) Powder in Packet Sig: One (1) +packet PO once a day. +27. Nitrostat 0.3 mg Tablet, Sublingual Sig: One (1) tablet +Sublingual three times a day as needed for chest pain: Take up +to 3 tablets 5 minutes apart as needed for chest pain and seek +immediate medical attention. +28. Outpatient Lab Work +Please check chemistries and liver function tests on [**Hospital1 766**], +[**11-7**] and fax the results to the office of Dr. [**First Name8 (NamePattern2) **] +[**Last Name (NamePattern1) 26894**] at [**Telephone/Fax (1) 16236**]. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Primary +1) Acute blood loss anemia +2) Acute gastritis +3) Candidal esophagitis +4) Clostridium difficile colitis + +Secondary +1) Coronary artery disease +2) Chronic systolic heart failure +3) Atrial fibrillation +4) Chronic kidney disease stage III +5) Hypothyroidism + + +Discharge Condition: +asymptomatic with stable vital signs. + + +Discharge Instructions: +You were admitted to the hospital with dark stools, likely from +erosions and inflammation in the lining of the stomach seen on +upper endoscopy. Your coumadin (warfarin) was discontinued due +to recurrent bleeding. Continue taking aspirin daily as +prescribed. Take protonix 2 times daily and a new medication +carafate (sucralfate) 4 times daily to help heal and protect the +stomach lining. + +Upper endoscopy also showed a fungal infection in the esophagus +which was partially treated with an antifungal medication. +Please continue taking Fluconazole through Tuesday, [**11-15**]. Please have blood drawn for chemistries and liver function +tests on [**Month (only) 766**], [**11-7**] and ensure that the results are +faxed to Dr. [**Last Name (STitle) 26895**] office at [**Telephone/Fax (1) 16236**]. + +You were diagnosed with a bacterial infection in the large +intestine which was partially treated with an antibiotic +medication. Please continue Flagyl (metronidazole) as prescribed +through Wednesday, [**11-9**]. Do not drink alcohol while +taking this medication due to the risks of side effects from +this combination. + +You no longer need to use the fluticasone inhaler if you are +also using advair. Please be sure to rinse out your mouth and +throat after using this medication to help prevent infection. + +Please continue taking your other medications as prescribed. + +Please adhere to a diet with less than 2 grams of sodium daily. +Please weight yourself daily and call your physician if your +weight increases by greater than 3 lbs. + +Please call the office of Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 26894**] at [**Telephone/Fax (1) 3329**] to +arrange a follow up appointment in 1 week. + +Please call the office of Dr. [**First Name8 (NamePattern2) 449**] [**Last Name (NamePattern1) 437**] at [**Telephone/Fax (1) 62**] to +arrange a follow up appointment in [**1-13**] weeks. + +Please follow up with Dr. [**First Name4 (NamePattern1) 636**] [**Last Name (NamePattern1) 1407**] on Friday, [**11-4**] at +1:00. The office phone number is [**Telephone/Fax (1) 463**]. + +Please call your physician or return to the Emergency Department +if you experience fever, chills, sweats, dizziness, +lightheadedness, difficulty or pain with swallowing, chest pain, +palpitations, shortness of breath, cough, abdominal pain, +vomiting, diarrhea, bloody or black stools, or leg swelling or +pain. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 21795**], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2140-11-4**] 1:00 +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-25**] +8:40 +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2140-12-19**] +1:00 + + + [**Name6 (MD) 251**] [**Name8 (MD) **] MD [**MD Number(1) 910**] + +Completed by:[**2140-10-30**]",157,2140-10-23 15:20:00,2140-10-30 14:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN;TELEMETRY;MELENA," +#acute gastritis - the patient was admitted to the icu overnight +for observation given reported hypotension prior to admission. +blood pressure was readily fluid-responsive and the patient +remained hemodynamically stable. melena resolved after admission +and hematocrit remained stable, obviating the need for blood +transfusion. he was treated with ppi gtt in the icu which was +changed to ppi [**hospital1 **] on the floor. the patient [**hospital1 1834**] egd +showing erosive gastritis and barretts esophagus but no active +bleeding. continued to hold coumadin. aspirin was restarted in +the setting of [**hospital1 **] ppi and carafate therapy which will be +continued after discharge at the recommendation of the +consulting gi team. he will follow up in [**hospital **] clinic, in part to +schedule surveillance endoscopy for the monitoring of barretts. + +. +#candidal esophagitis - egd also revealed candidal esophagitis +which had been present on endoscopy 6 months prior and perhaps +inadequately treated with a 10-day course of fluconazole. hiv ab +test was negative at that time. a 3-week course of oral +fluconazole was started with lfts to be rechecked 1 week after +discharge. he was counseled regarding the proper use of his +corticosteroid inhalers including rinsing thoroughly after use. +. +#c. difficile colitis - the patient was started on a 2 week +course of flagyl. he was placed on contact precautions. [**name2 (ni) **] was +counseled not to drink alcohol while taking metronidazole. +. +#abdominal/back pain - this pain reportedly had been present for +several years but had subacutely worsened over the past [**6-23**] +months. paraspinal muscle tenderness on examination was +suggestive of musculoskeletal pathology. cta abd/pelvis showed +sigmoid diverticulosis but no evidence of mesenteric ischemia or +aaa. lumbar plain film showed only chronic degenerative changes +but no compression deformity or lytic lesion. stable hematocrit +made a rp bleed unlikely. urinalysis, lfts, calcium, and +spep/upep were normal. pain was well-controlled with tylenol. +. +#chronic systolic chf - the patient appeared euvolemic without +signs or symptoms of acute chf. acei had been discontinued prior +to admission due to hypotension. he will continue on +beta-blocker, digoxin, and diuretic therapy after discharge. +. +#atrial fibrillation - coumadin was held due to recurrent ugib, +as above. aspirin was continued. he was encouraged to follow up +with his cardiologist as soon as possible. +. +#chronic kidney disease stage iii - creatinine remained at +baseline. medications were dosed accordingly. +. +#hyperlipidemia - continued statin. +. +#hypothyroidism - continued levothyroxine. +. +#asthma - continued home regimen with counseling regarding +proper use of steroid inhalers, as above. +. +#nutrition - heart-healthy diet. +. +#propylaxis - pneumoboots, ppi + + ","PRIMARY: [Other specified gastritis, with hemorrhage] +SECONDARY: [Intestinal infection due to Clostridium difficile; Candidal esophagitis; Chronic systolic heart failure; Acute posthemorrhagic anemia; Congestive heart failure, unspecified; Atrial fibrillation; Long-term (current) use of anticoagulants; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Other and unspecified hyperlipidemia; Aortocoronary bypass status; Esophageal reflux; Unspecified acquired hypothyroidism; Chronic kidney disease, Stage III (moderate); Other specified forms of chronic ischemic heart disease; Asthma, unspecified type, unspecified; Automatic implantable cardiac defibrillator in situ; Aortic valve disorders; Barrett's esophagus; Diverticulosis of colon (without mention of hemorrhage); Unspecified analgesic and antipyretic causing adverse effects in therapeutic use]" +10774,197363.0,8555,2141-04-05,8552,130230.0,2140-10-18,Discharge summary,"Admission Date: [**2140-10-11**] Discharge Date: [**2140-10-18**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 898**] +Chief Complaint: +Black stools, chest pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Pt is a 72 yo M with PMH of CAD s/p CABG and PCI to L circ, AS, +VT/VF arrest with BiV pacer, CHF (EF 20%), afib on coumadin, CRI +(BL Cr 1.6-2), and diverticulosis. H/O GIB w most recent +admission on [**2140-9-12**]. Now with black stools since MN accompanied +by mid-sternal CP with radiation to left arm. Took all BP meds +this AM (per pt, usual BP in the 90s range). Also c/o +lightheadedness and SOB. +. +In the ED, VS: T 98 BP 105/76 HR 75 RR 21 97%2L. Guaiac pos +black stool. Patient received morphine for CP with mild +improvement in pain. EKG was v-paced with no obvious ST/TW +changes. NG lavage was negative x 2. He received 2U FFP and 5 mg +PO vitamin K for INR reversal and 1L IVFs. Seen by Cards in ED, +recommennd echo in AM, +. +On arrival to the MICU, pt states his discomfort has imporved,d +own from [**8-21**] to [**4-21**], described as dull ache in chest, +non-radiating, constant since 11 PM last night, as well as +discomfort in the lower abdomen (identical to past abd pain in +setting of past GIB x 2). + nausea. + + +Past Medical History: +--CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +--s/p VT/VF arrest, s/p ICD placement in [**2135**] +--Ischemic cardiomyopathy with an ED of 20%, s/p BiV pacer [**10-18**] + +--Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +--PAF +--CKD with baseline Cr. 1.6-2 +--Hyperlipidemia +--Asthma +--Anxiety +--Alzheimer's dementia +--Hypothyroidism +--GI bleed of unknown etiology [**2138**]. EGD revealed esophagitis, +Barrett's esophagus, and duodenitis. No ulcers. +--Diverticulosis +--GERD +--S/P Cholecystectomy + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Worked as an off-set printer in [**Location (un) 686**], where he +continues to live with his wife. Father of five children. +Retired 6 years ago, and since his recent heart problems, says +he rarely leaves the house. Most of his time is spent in front +of the television with his wife handling their affairs at home. +No history of smoking, past or present. Patient was a heavy +drinker until 20 years ago, when he stopped completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + + +Family History: +Non-contributory. + +Physical Exam: +VS: afebrile Heart rate: 75 paced Normotensive and satting +well on room air +GEN: Elderly male, NAD, lying in bed +HEENT: PERRL, anicteric +NECK: Supple, no JVD +CHEST: CTAB +CV: s1s2 + SEM, + heave with lateral displacement of the PMI +ABD: +BS, soft, ND, mild TTP lower quadrants bilaterally, no +rebound or guarding +BACK: No CVAT +Rectak: Trace guaiac positive black stool +EXT: WD/WP, no pedal edema +NEURO: A&O x 3, MAE, speech fluent, nonfocal + + +Pertinent Results: +CBC: +[**2140-10-11**] 12:45PM BLOOD WBC-9.9 RBC-4.59* Hgb-13.3* Hct-39.8* +MCV-87 MCH-29.1 MCHC-33.5 RDW-14.2 Plt Ct-149* +[**2140-10-13**] 06:38AM BLOOD WBC-7.8 RBC-4.02* Hgb-11.7* Hct-34.7* +MCV-87 MCH-29.0 MCHC-33.6 RDW-14.0 Plt Ct-121* +[**2140-10-18**] 05:27AM BLOOD WBC-6.6 RBC-4.06* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.2 MCHC-33.8 RDW-14.9 Plt Ct-152 + +Coags: +[**2140-10-11**] 12:45PM BLOOD PT-24.7* PTT-29.8 INR(PT)-2.4* +[**2140-10-14**] 04:45AM BLOOD PT-18.4* PTT-29.4 INR(PT)-1.7* +[**2140-10-17**] 04:55AM BLOOD PT-15.2* PTT-31.5 INR(PT)-1.3* + +Chemistry: +[**2140-10-11**] 12:45PM BLOOD Glucose-102 UreaN-31* Creat-2.0* Na-140 +K-3.9 Cl-100 HCO3-30 AnGap-14 +[**2140-10-13**] 06:38AM BLOOD Glucose-68* UreaN-26* Creat-1.5* Na-142 +K-4.1 Cl-103 HCO3-27 AnGap-16 +[**2140-10-18**] 05:27AM BLOOD Glucose-85 UreaN-22* Creat-1.7* Na-141 +K-3.9 Cl-102 HCO3-30 AnGap-13 +[**2140-10-11**] 12:45PM BLOOD Calcium-9.5 Phos-2.7 Mg-2.2 +[**2140-10-14**] 04:45AM BLOOD Calcium-8.6 Phos-1.8* Mg-2.1 +[**2140-10-17**] 04:55AM BLOOD Calcium-9.3 Phos-3.1 Mg-1.8 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD CK(CPK)-97 +[**2140-10-12**] 03:22AM BLOOD CK(CPK)-90 +[**2140-10-12**] 10:26PM BLOOD CK(CPK)-102 + +LFTs: +[**2140-10-11**] 07:15PM BLOOD ALT-24 AST-38 CK(CPK)-92 AlkPhos-86 +Amylase-72 TotBili-0.3 + +Lipase: +[**2140-10-11**] 07:15PM BLOOD Lipase-35 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD cTropnT-0.01 +[**2140-10-12**] 03:22AM BLOOD CK-MB-NotDone cTropnT-0.02* +[**2140-10-12**] 10:26PM BLOOD CK-MB-4 cTropnT-0.01 + +Digoxin: +[**2140-10-11**] 12:45PM BLOOD Digoxin-0.4* + +ECG: Sinus rhythm with demand ventricular pacing +Ventricular premature complexes +Since previous tracing of the same date, QRS width shorter, +assess LV pacing + +CXR: FINDINGS: The pacer/defibrillator leads are again seen +terminating in the right ventricle and coronary sinus. There are +median sternotomy wires. An additional disconnected pacer wire +is seen within the left chest wall, as on prior. There is no +evidence of pneumonia. There is cardiomegaly, without CHF. There +is no pneumothorax or pleural effusion. Degenerative changes are +seen at the right humeral head. The bones are otherwise +unremarkable. +IMPRESSION: No acute intrathoracic process. Cardiomegaly without +CHF. + +ECHO: The left atrium is dilated. Left ventricular wall +thicknesses are normal. The left ventricular cavity is severely +dilated. There is severe regional left ventricular systolic +dysfunction with akinesis of all inferior and inferolateral +segments and of the basal lateral segments. The other segments +are severely hypokinetic. There is no ventricular septal defect. +The right ventricular cavity is mildly dilated with mild global +free wall hypokinesis. The aortic root is moderately dilated at +the sinus level. The aortic valve leaflets are severely +thickened/deformed. There is moderate to severe aortic valve +stenosis (area 0.8-1.0cm2). No aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Moderate (2+) mitral regurgitation is seen. +There is mild pulmonary artery systolic hypertension. There is +no pericardial effusion. +IMPRESSION: Severe focal and global LV systolic dysfunction. +Moderate to severe aortic stenosis. Moderate mitral +regurgitation. + +Abdominal XR: FOUR VIEWS OF THE ABDOMEN: There are moderately +dilated loops of small bowel, and multiple air-fluid levels are +demonstrated on the left lateral decubitus. There is no evidence +of free air. Cholecystectomy clips in the right upper quadrant +and the right hip arthroplasty are again identified. There is +air within the rectum. The left hip demonstrates moderate +degenerative change. Midline sternotomy wires and a pacing +device are identified. +IMPRESSION: Moderately dilated loops of small bowel and +air-fluid levels are consistent with ileus or early/partial +small-bowel obstruction. + + +Brief Hospital Course: +The patient was admitted to the MICU for monitoring and serial +Hcts. His BP reamined in the 90-110 systolic range. A Hct drop +from 39 to 32 was noted, which then stabilized. GI saw the +patient, no plan for emergent scope. Cardiology saw the pt and +recommended an echocardiogram. Cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. Diuretics and anti-hypertensives were held. +. + +A/P: 72 yo M with MMP including CAD, CHF, CRI admit with GIB, +abdominal pain, and chest pain, now callout from MICU. +. +# GI bleed/Abd pain: Hx GI bleeding in the past, recent EGD by +GI showed erosions in stomach and duodenum c/w NSAID +gastropathy, had a normal [**Last Name (un) **] in [**Month (only) 547**]. Hct stable and has not +required transfusion. No evidence of active bleed. LFTs normal +on admit. Mesenteric ischemia was considered as patient +stabalized this was not pursed. He had some persistent nausea +which improved with reglan. He was discharged in omeprazole. + +. +# Chest pain: with extensive CAD and CHF history. Echo done this +admit as above. He was ruled out for an MI. +. +# Systolic heart failure: Focal akinesia as above. He was +satting well on room air and did not have clinical evidence of +heart failure +. +# Afib: Medications were continued, coumadin was stopped. +. +# Chronic renal insufficiency: Baseline cr 1.6-2. Currently at +baseline. +. +# Hyperlipidemia: +- continue statin +. +# Hypothyroidism: +- continue levothyroxine +. +# Asthma: +- continue home meds +. +CODE: Full (confirmed with patient) +. +Communication: Pt, wife [**Doctor First Name **] [**Telephone/Fax (1) 30058**]) + + +Medications on Admission: +Sotalol 80mg [**Hospital1 **] +Lipitor 20mg daily +Donepezil 5mg daily +Quetiapine 25mg, 3tabs qAM, 1tab noon, 3tabs qHS +Celexa 60mg daily +Protonix 40mg daily +ASA 81mg daily +Clonazepam 0.5mg TID PRN +Lisinopril 5mg daily +Digoxin 125mcg, [**1-13**] tab daily +K-Dur daily +Spironolactone 25mg daily +Levothyroxin3e 112mcg daily +Trazodone 25mg qHS +Mexiletine 150mg TID +Albuterol MDI 2puf q6hPRN +Fluticasone 110mcg 2puff [**Hospital1 **] +Toprol SL 50mg daily +Lasix 40mg TID +Coumadin + + +Discharge Medications: +1. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +2. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Donepezil 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). + +4. Citalopram 40 mg Tablet Sig: 1.5 Tablets PO once a day. +5. Quetiapine 25 mg Tablet Sig: as directed Tablet PO three +times a day: take 2 tabs every morning, 1 tab at noontime, and 3 +tabs at bedtime. +6. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO three times a +day as needed for anxiety. +7. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +9. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +10. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime) as needed. +11. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +12. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed for shortness of breath or +wheezing. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation [**Hospital1 **] (2 times a day). +14. NitroQuick 0.4 mg Tablet, Sublingual Sig: One (1) +Sublingual as needed as needed for chest pain: as previously +directed, take up to 3 tabs five minutes apart. +15. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +16. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +17. Aspirin 81 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO DAILY (Daily). +18. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY +(Daily). +19. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +20. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times +a day) as needed for nausea. +Disp:*45 Tablet(s)* Refills:*2* +21. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +22. Furosemide 80 mg Tablet Sig: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Gastrointestinal bleeding +. +Congestive heart failure, systolic dysfunction, chronic +Coronary artery disease +Atrial fibrillation +Chronic kidney disease +Alzheimer's dementia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted with bleeding, likely from your stomach. We +think that this was in part related to taking coumadin and after +much discussion, we have stopped this medication. You blood +counts have been stable. +. +Please return to the hospital or call your doctor if you have +worsening abdominal pain, pain after eating, blood in your vomit +or stools, dark colored stools, chest pain, shortness of breath, +or any new symptoms that you are concerned about. +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +. +Since you were admitted we have made the following medication +changes: +* Please stop taking COUMADIN. +* Your lasix dose was increased to 80 mg daily. + +Followup Instructions: +Please call your primary care physician, [**Last Name (NamePattern4) **]. [**Last Name (STitle) 26894**], to schedule +a followup appointment within 2 weeks. +. +You also have the following upcoming appointments at [**Hospital1 18**]: +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 21795**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-4**] 1:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-25**] 8:40 +DEVICE CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2140-12-19**] 1:00 + + + +",169,2140-10-11 14:34:00,2140-10-18 15:38:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN;TELEMETRY;GI BLEED," +the patient was admitted to the micu for monitoring and serial +hcts. his bp reamined in the 90-110 systolic range. a hct drop +from 39 to 32 was noted, which then stabilized. gi saw the +patient, no plan for emergent scope. cardiology saw the pt and +recommended an echocardiogram. cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. diuretics and anti-hypertensives were held. +. + +a/p: 72 yo m with mmp including cad, chf, cri admit with gib, +abdominal pain, and chest pain, now callout from micu. +. +# gi bleed/abd pain: hx gi bleeding in the past, recent egd by +gi showed erosions in stomach and duodenum c/w nsaid +gastropathy, had a normal [**last name (un) **] in [**month (only) 547**]. hct stable and has not +required transfusion. no evidence of active bleed. lfts normal +on admit. mesenteric ischemia was considered as patient +stabalized this was not pursed. he had some persistent nausea +which improved with reglan. he was discharged in omeprazole. + +. +# chest pain: with extensive cad and chf history. echo done this +admit as above. he was ruled out for an mi. +. +# systolic heart failure: focal akinesia as above. he was +satting well on room air and did not have clinical evidence of +heart failure +. +# afib: medications were continued, coumadin was stopped. +. +# chronic renal insufficiency: baseline cr 1.6-2. currently at +baseline. +. +# hyperlipidemia: +- continue statin +. +# hypothyroidism: +- continue levothyroxine +. +# asthma: +- continue home meds +. +code: full (confirmed with patient) +. +communication: pt, wife [**doctor first name **] [**telephone/fax (1) 30058**]) + + + ","PRIMARY: [Hemorrhage of gastrointestinal tract, unspecified] +SECONDARY: [Acute on chronic systolic heart failure; Atrial fibrillation; Other and unspecified angina pectoris; Hypovolemia; Aortic valve disorders; Asthma, unspecified type, unspecified; Chronic kidney disease, unspecified; Aortocoronary bypass status; Long-term (current) use of anticoagulants; Automatic implantable cardiac defibrillator in situ; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Congestive heart failure, unspecified; Unspecified analgesic and antipyretic causing adverse effects in therapeutic use; Anticoagulants causing adverse effects in therapeutic use; Other specified forms of chronic ischemic heart disease; Other and unspecified hyperlipidemia; Barrett's esophagus; Diverticulosis of colon (without mention of hemorrhage); Unspecified acquired hypothyroidism]" +10774,173586.0,8554,2141-03-30,8552,130230.0,2140-10-18,Discharge summary,"Admission Date: [**2140-10-11**] Discharge Date: [**2140-10-18**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 898**] +Chief Complaint: +Black stools, chest pain + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Pt is a 72 yo M with PMH of CAD s/p CABG and PCI to L circ, AS, +VT/VF arrest with BiV pacer, CHF (EF 20%), afib on coumadin, CRI +(BL Cr 1.6-2), and diverticulosis. H/O GIB w most recent +admission on [**2140-9-12**]. Now with black stools since MN accompanied +by mid-sternal CP with radiation to left arm. Took all BP meds +this AM (per pt, usual BP in the 90s range). Also c/o +lightheadedness and SOB. +. +In the ED, VS: T 98 BP 105/76 HR 75 RR 21 97%2L. Guaiac pos +black stool. Patient received morphine for CP with mild +improvement in pain. EKG was v-paced with no obvious ST/TW +changes. NG lavage was negative x 2. He received 2U FFP and 5 mg +PO vitamin K for INR reversal and 1L IVFs. Seen by Cards in ED, +recommennd echo in AM, +. +On arrival to the MICU, pt states his discomfort has imporved,d +own from [**8-21**] to [**4-21**], described as dull ache in chest, +non-radiating, constant since 11 PM last night, as well as +discomfort in the lower abdomen (identical to past abd pain in +setting of past GIB x 2). + nausea. + + +Past Medical History: +--CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +--s/p VT/VF arrest, s/p ICD placement in [**2135**] +--Ischemic cardiomyopathy with an ED of 20%, s/p BiV pacer [**10-18**] + +--Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +--PAF +--CKD with baseline Cr. 1.6-2 +--Hyperlipidemia +--Asthma +--Anxiety +--Alzheimer's dementia +--Hypothyroidism +--GI bleed of unknown etiology [**2138**]. EGD revealed esophagitis, +Barrett's esophagus, and duodenitis. No ulcers. +--Diverticulosis +--GERD +--S/P Cholecystectomy + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Worked as an off-set printer in [**Location (un) 686**], where he +continues to live with his wife. Father of five children. +Retired 6 years ago, and since his recent heart problems, says +he rarely leaves the house. Most of his time is spent in front +of the television with his wife handling their affairs at home. +No history of smoking, past or present. Patient was a heavy +drinker until 20 years ago, when he stopped completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + + +Family History: +Non-contributory. + +Physical Exam: +VS: afebrile Heart rate: 75 paced Normotensive and satting +well on room air +GEN: Elderly male, NAD, lying in bed +HEENT: PERRL, anicteric +NECK: Supple, no JVD +CHEST: CTAB +CV: s1s2 + SEM, + heave with lateral displacement of the PMI +ABD: +BS, soft, ND, mild TTP lower quadrants bilaterally, no +rebound or guarding +BACK: No CVAT +Rectak: Trace guaiac positive black stool +EXT: WD/WP, no pedal edema +NEURO: A&O x 3, MAE, speech fluent, nonfocal + + +Pertinent Results: +CBC: +[**2140-10-11**] 12:45PM BLOOD WBC-9.9 RBC-4.59* Hgb-13.3* Hct-39.8* +MCV-87 MCH-29.1 MCHC-33.5 RDW-14.2 Plt Ct-149* +[**2140-10-13**] 06:38AM BLOOD WBC-7.8 RBC-4.02* Hgb-11.7* Hct-34.7* +MCV-87 MCH-29.0 MCHC-33.6 RDW-14.0 Plt Ct-121* +[**2140-10-18**] 05:27AM BLOOD WBC-6.6 RBC-4.06* Hgb-11.9* Hct-35.1* +MCV-87 MCH-29.2 MCHC-33.8 RDW-14.9 Plt Ct-152 + +Coags: +[**2140-10-11**] 12:45PM BLOOD PT-24.7* PTT-29.8 INR(PT)-2.4* +[**2140-10-14**] 04:45AM BLOOD PT-18.4* PTT-29.4 INR(PT)-1.7* +[**2140-10-17**] 04:55AM BLOOD PT-15.2* PTT-31.5 INR(PT)-1.3* + +Chemistry: +[**2140-10-11**] 12:45PM BLOOD Glucose-102 UreaN-31* Creat-2.0* Na-140 +K-3.9 Cl-100 HCO3-30 AnGap-14 +[**2140-10-13**] 06:38AM BLOOD Glucose-68* UreaN-26* Creat-1.5* Na-142 +K-4.1 Cl-103 HCO3-27 AnGap-16 +[**2140-10-18**] 05:27AM BLOOD Glucose-85 UreaN-22* Creat-1.7* Na-141 +K-3.9 Cl-102 HCO3-30 AnGap-13 +[**2140-10-11**] 12:45PM BLOOD Calcium-9.5 Phos-2.7 Mg-2.2 +[**2140-10-14**] 04:45AM BLOOD Calcium-8.6 Phos-1.8* Mg-2.1 +[**2140-10-17**] 04:55AM BLOOD Calcium-9.3 Phos-3.1 Mg-1.8 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD CK(CPK)-97 +[**2140-10-12**] 03:22AM BLOOD CK(CPK)-90 +[**2140-10-12**] 10:26PM BLOOD CK(CPK)-102 + +LFTs: +[**2140-10-11**] 07:15PM BLOOD ALT-24 AST-38 CK(CPK)-92 AlkPhos-86 +Amylase-72 TotBili-0.3 + +Lipase: +[**2140-10-11**] 07:15PM BLOOD Lipase-35 + +Cardiac Enzymes: +[**2140-10-11**] 12:45PM BLOOD cTropnT-0.01 +[**2140-10-12**] 03:22AM BLOOD CK-MB-NotDone cTropnT-0.02* +[**2140-10-12**] 10:26PM BLOOD CK-MB-4 cTropnT-0.01 + +Digoxin: +[**2140-10-11**] 12:45PM BLOOD Digoxin-0.4* + +ECG: Sinus rhythm with demand ventricular pacing +Ventricular premature complexes +Since previous tracing of the same date, QRS width shorter, +assess LV pacing + +CXR: FINDINGS: The pacer/defibrillator leads are again seen +terminating in the right ventricle and coronary sinus. There are +median sternotomy wires. An additional disconnected pacer wire +is seen within the left chest wall, as on prior. There is no +evidence of pneumonia. There is cardiomegaly, without CHF. There +is no pneumothorax or pleural effusion. Degenerative changes are +seen at the right humeral head. The bones are otherwise +unremarkable. +IMPRESSION: No acute intrathoracic process. Cardiomegaly without +CHF. + +ECHO: The left atrium is dilated. Left ventricular wall +thicknesses are normal. The left ventricular cavity is severely +dilated. There is severe regional left ventricular systolic +dysfunction with akinesis of all inferior and inferolateral +segments and of the basal lateral segments. The other segments +are severely hypokinetic. There is no ventricular septal defect. +The right ventricular cavity is mildly dilated with mild global +free wall hypokinesis. The aortic root is moderately dilated at +the sinus level. The aortic valve leaflets are severely +thickened/deformed. There is moderate to severe aortic valve +stenosis (area 0.8-1.0cm2). No aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Moderate (2+) mitral regurgitation is seen. +There is mild pulmonary artery systolic hypertension. There is +no pericardial effusion. +IMPRESSION: Severe focal and global LV systolic dysfunction. +Moderate to severe aortic stenosis. Moderate mitral +regurgitation. + +Abdominal XR: FOUR VIEWS OF THE ABDOMEN: There are moderately +dilated loops of small bowel, and multiple air-fluid levels are +demonstrated on the left lateral decubitus. There is no evidence +of free air. Cholecystectomy clips in the right upper quadrant +and the right hip arthroplasty are again identified. There is +air within the rectum. The left hip demonstrates moderate +degenerative change. Midline sternotomy wires and a pacing +device are identified. +IMPRESSION: Moderately dilated loops of small bowel and +air-fluid levels are consistent with ileus or early/partial +small-bowel obstruction. + + +Brief Hospital Course: +The patient was admitted to the MICU for monitoring and serial +Hcts. His BP reamined in the 90-110 systolic range. A Hct drop +from 39 to 32 was noted, which then stabilized. GI saw the +patient, no plan for emergent scope. Cardiology saw the pt and +recommended an echocardiogram. Cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. Diuretics and anti-hypertensives were held. +. + +A/P: 72 yo M with MMP including CAD, CHF, CRI admit with GIB, +abdominal pain, and chest pain, now callout from MICU. +. +# GI bleed/Abd pain: Hx GI bleeding in the past, recent EGD by +GI showed erosions in stomach and duodenum c/w NSAID +gastropathy, had a normal [**Last Name (un) **] in [**Month (only) 547**]. Hct stable and has not +required transfusion. No evidence of active bleed. LFTs normal +on admit. Mesenteric ischemia was considered as patient +stabalized this was not pursed. He had some persistent nausea +which improved with reglan. He was discharged in omeprazole. + +. +# Chest pain: with extensive CAD and CHF history. Echo done this +admit as above. He was ruled out for an MI. +. +# Systolic heart failure: Focal akinesia as above. He was +satting well on room air and did not have clinical evidence of +heart failure +. +# Afib: Medications were continued, coumadin was stopped. +. +# Chronic renal insufficiency: Baseline cr 1.6-2. Currently at +baseline. +. +# Hyperlipidemia: +- continue statin +. +# Hypothyroidism: +- continue levothyroxine +. +# Asthma: +- continue home meds +. +CODE: Full (confirmed with patient) +. +Communication: Pt, wife [**Doctor First Name **] [**Telephone/Fax (1) 30058**]) + + +Medications on Admission: +Sotalol 80mg [**Hospital1 **] +Lipitor 20mg daily +Donepezil 5mg daily +Quetiapine 25mg, 3tabs qAM, 1tab noon, 3tabs qHS +Celexa 60mg daily +Protonix 40mg daily +ASA 81mg daily +Clonazepam 0.5mg TID PRN +Lisinopril 5mg daily +Digoxin 125mcg, [**1-13**] tab daily +K-Dur daily +Spironolactone 25mg daily +Levothyroxin3e 112mcg daily +Trazodone 25mg qHS +Mexiletine 150mg TID +Albuterol MDI 2puf q6hPRN +Fluticasone 110mcg 2puff [**Hospital1 **] +Toprol SL 50mg daily +Lasix 40mg TID +Coumadin + + +Discharge Medications: +1. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +2. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Donepezil 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). + +4. Citalopram 40 mg Tablet Sig: 1.5 Tablets PO once a day. +5. Quetiapine 25 mg Tablet Sig: as directed Tablet PO three +times a day: take 2 tabs every morning, 1 tab at noontime, and 3 +tabs at bedtime. +6. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO three times a +day as needed for anxiety. +7. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +9. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +10. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime) as needed. +11. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +12. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed for shortness of breath or +wheezing. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation [**Hospital1 **] (2 times a day). +14. NitroQuick 0.4 mg Tablet, Sublingual Sig: One (1) +Sublingual as needed as needed for chest pain: as previously +directed, take up to 3 tabs five minutes apart. +15. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +16. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +17. Aspirin 81 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO DAILY (Daily). +18. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY +(Daily). +19. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +20. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times +a day) as needed for nausea. +Disp:*45 Tablet(s)* Refills:*2* +21. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +22. Furosemide 80 mg Tablet Sig: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Gastrointestinal bleeding +. +Congestive heart failure, systolic dysfunction, chronic +Coronary artery disease +Atrial fibrillation +Chronic kidney disease +Alzheimer's dementia + + +Discharge Condition: +Stable + + +Discharge Instructions: +You were admitted with bleeding, likely from your stomach. We +think that this was in part related to taking coumadin and after +much discussion, we have stopped this medication. You blood +counts have been stable. +. +Please return to the hospital or call your doctor if you have +worsening abdominal pain, pain after eating, blood in your vomit +or stools, dark colored stools, chest pain, shortness of breath, +or any new symptoms that you are concerned about. +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +. +Since you were admitted we have made the following medication +changes: +* Please stop taking COUMADIN. +* Your lasix dose was increased to 80 mg daily. + +Followup Instructions: +Please call your primary care physician, [**Last Name (NamePattern4) **]. [**Last Name (STitle) 26894**], to schedule +a followup appointment within 2 weeks. +. +You also have the following upcoming appointments at [**Hospital1 18**]: +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 21795**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-4**] 1:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-25**] 8:40 +DEVICE CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2140-12-19**] 1:00 + + + +",163,2140-10-11 14:34:00,2140-10-18 15:38:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN;TELEMETRY;GI BLEED," +the patient was admitted to the micu for monitoring and serial +hcts. his bp reamined in the 90-110 systolic range. a hct drop +from 39 to 32 was noted, which then stabilized. gi saw the +patient, no plan for emergent scope. cardiology saw the pt and +recommended an echocardiogram. cardiac enzymes were cycled; the +first two sets were negative, the third troponin was 0.02 (has +been similar in the past), in the setting of constant chest pain +x 24 hours. diuretics and anti-hypertensives were held. +. + +a/p: 72 yo m with mmp including cad, chf, cri admit with gib, +abdominal pain, and chest pain, now callout from micu. +. +# gi bleed/abd pain: hx gi bleeding in the past, recent egd by +gi showed erosions in stomach and duodenum c/w nsaid +gastropathy, had a normal [**last name (un) **] in [**month (only) 547**]. hct stable and has not +required transfusion. no evidence of active bleed. lfts normal +on admit. mesenteric ischemia was considered as patient +stabalized this was not pursed. he had some persistent nausea +which improved with reglan. he was discharged in omeprazole. + +. +# chest pain: with extensive cad and chf history. echo done this +admit as above. he was ruled out for an mi. +. +# systolic heart failure: focal akinesia as above. he was +satting well on room air and did not have clinical evidence of +heart failure +. +# afib: medications were continued, coumadin was stopped. +. +# chronic renal insufficiency: baseline cr 1.6-2. currently at +baseline. +. +# hyperlipidemia: +- continue statin +. +# hypothyroidism: +- continue levothyroxine +. +# asthma: +- continue home meds +. +code: full (confirmed with patient) +. +communication: pt, wife [**doctor first name **] [**telephone/fax (1) 30058**]) + + + ","PRIMARY: [Hemorrhage of gastrointestinal tract, unspecified] +SECONDARY: [Acute on chronic systolic heart failure; Atrial fibrillation; Other and unspecified angina pectoris; Hypovolemia; Aortic valve disorders; Asthma, unspecified type, unspecified; Chronic kidney disease, unspecified; Aortocoronary bypass status; Long-term (current) use of anticoagulants; Automatic implantable cardiac defibrillator in situ; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Congestive heart failure, unspecified; Unspecified analgesic and antipyretic causing adverse effects in therapeutic use; Anticoagulants causing adverse effects in therapeutic use; Other specified forms of chronic ischemic heart disease; Other and unspecified hyperlipidemia; Barrett's esophagus; Diverticulosis of colon (without mention of hemorrhage); Unspecified acquired hypothyroidism]" +10774,173586.0,8554,2141-03-30,8553,142104.0,2140-10-30,Discharge summary,"Admission Date: [**2140-10-23**] Discharge Date: [**2140-10-30**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 905**] +Chief Complaint: +melena + +Major Surgical or Invasive Procedure: +Esophagogastroduodenoscopy [**2140-10-26**] +Esophagogastroduodenoscopy [**2140-10-27**] + + +History of Present Illness: +72 yo M with PMH of CAD s/p CABG and PCI to LCx, AS, VT/VF +arrest with BiV pacer, CHF (EF 20%), afib on coumadin, CRI (BL +Cr 1.6-2), and diverticulosis admitted with abdominal pain and +melena for two days. Reported hypotension by VNA to 96/P. The +patient has a history of recurrent GIB with most recent +admission on [**2140-10-11**] to [**10-18**]. During last hospital stay the +patient was admitted to the MICU for monitoring and serial Hcts. +A Hct drop from 39 to 32 was noted, which then stabilized. GI +saw the patient and deferred scope. His coumadin was +discontinued at this time due to recurrent bleeding. He was also +admitted on [**9-12**] with melena and abd pain. EGD showed Barrett's +esophagitis, gastritis, and duodenitis. He has a history of +polyp removal in the cecum and one in the ascending colon in +[**4-19**], histology was adenomatous. He also had a capsule study at +that time, that did not show additional source of bleed in the +small bowel. + +In ED, Vitals T 98.2, HR 78, BP 111/61, RR 18, 100% 2L NC. NG +lavage showed scant blood initially which cleared with lavage. +HCT stable. He was given morphine 4mg X3. No ASA given. Bolused +with 40mg IV pantoprazole X1. + +On arrival to MICU, pt is in no acute distress. Reports [**5-17**] +black, tarry stools last pm with associated dizziness. Pt has +also had ongoing abdominal and back pain since discharge last +week. His pain is constant and non-radiating located in his +chest, abdomen and back. + +Past Medical History: +CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +s/p VT/VF arrest, s/p ICD placement in [**2135**] +iCMP (EF 20%) s/p BiV pacer [**10-18**] +Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +AFib +CKD Stage III b/l Cr. ~1.6 +Hyperlipidemia +Asthma +Anxiety +Alzheimer's dementia +Hypothyroidism +Diverticulosis +GERD +s/p CCY + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Father of five children. No history of smoking. +Patient was a heavy drinker until 20 years ago, when he stopped +completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + +Family History: +Non-contributory + +Physical Exam: +DISCHARGE PHYSICAL EXAM +V/S: 99.1, 97.6, 120/70-102/62, 80s, 16, 94% RA +GEN - Obese gentleman appears comfortable, NAD +HEENT- sclera anicteric, OP clear with MMM +NECK: supple without JVD, delayed carotid upstroke no bruit +CV: reg rate nl S1 no S2 III/VI SEM at LUSB +PULM: CTAB no w/r/r +ABD: soft NTND normoactive BS no organomegaly +EXT- warm, dry diminished distal pulses no c/c/e +NEURO: A&Ox3 + +Pertinent Results: +[**2140-10-30**] 08:20AM BLOOD WBC-7.0 RBC-3.95* Hgb-11.7* Hct-34.5* +MCV-87 MCH-29.5 MCHC-33.8 RDW-14.2 Plt Ct-198 +[**2140-10-29**] 08:10AM BLOOD WBC-5.6 RBC-3.82* Hgb-11.2* Hct-33.2* +MCV-87 MCH-29.4 MCHC-33.7 RDW-14.7 Plt Ct-186 +[**2140-10-28**] 07:35AM BLOOD WBC-5.8 RBC-3.60* Hgb-10.5* Hct-31.5* +MCV-88 MCH-29.1 MCHC-33.2 RDW-14.2 Plt Ct-167 +[**2140-10-27**] 07:00AM BLOOD WBC-6.5 RBC-3.66* Hgb-10.7* Hct-32.0* +MCV-87 MCH-29.1 MCHC-33.4 RDW-14.3 Plt Ct-160 +[**2140-10-26**] 06:10AM BLOOD WBC-12.4* RBC-4.01* Hgb-12.0* Hct-34.6* +MCV-86 MCH-29.9 MCHC-34.6 RDW-14.5 Plt Ct-164 +[**2140-10-25**] 06:00AM BLOOD WBC-9.0 RBC-4.04* Hgb-11.5* Hct-35.4* +MCV-88 MCH-28.5 MCHC-32.6 RDW-14.5 Plt Ct-176 +[**2140-10-24**] 07:52PM BLOOD Hct-34.6* +[**2140-10-24**] 04:57PM BLOOD Hct-33.4* +[**2140-10-24**] 06:55AM BLOOD WBC-7.9 RBC-4.09* Hgb-12.1* Hct-35.6* +MCV-87 MCH-29.5 MCHC-33.9 RDW-14.9 Plt Ct-181 +[**2140-10-24**] 01:05AM BLOOD Hct-34.5* +[**2140-10-23**] 06:45PM BLOOD WBC-10.1 RBC-4.03* Hgb-11.8* Hct-35.0* +MCV-87 MCH-29.2 MCHC-33.6 RDW-14.4 Plt Ct-175 +[**2140-10-23**] 12:58PM BLOOD WBC-7.7 RBC-4.21* Hgb-12.1* Hct-36.1* +MCV-86 MCH-28.8 MCHC-33.6 RDW-15.0 Plt Ct-169 +[**2140-10-28**] 07:35AM BLOOD ALT-18 AST-20 AlkPhos-86 TotBili-0.2 +[**2140-10-24**] 08:19AM BLOOD CK(CPK)-103 +[**2140-10-24**] 01:05AM BLOOD CK(CPK)-124 +[**2140-10-23**] 12:58PM BLOOD CK(CPK)-189* +[**2140-10-24**] 08:19AM BLOOD CK-MB-3 cTropnT-0.01 +[**2140-10-23**] 12:58PM BLOOD cTropnT-0.01 +[**2140-10-24**] 08:14PM BLOOD Lactate-0.9 +. +[**2140-10-26**] 12:52 pm STOOL CONSISTENCY: NOT APPLICABLE + Source: Stool. + + **FINAL REPORT [**2140-10-27**]** + + CLOSTRIDIUM DIFFICILE TOXIN A & B TEST (Final [**2140-10-27**]): + REPORTED BY PHONE TO [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) 30063**] @ 3:55A [**2140-10-27**]. + CLOSTRIDIUM DIFFICILE. + FECES POSITIVE FOR C. DIFFICILE TOXIN BY EIA. +. +[**2140-10-25**] CT OF THE ABDOMEN WITH IV CONTRAST: +Within the visualized lung bases, there is atelectasis within +the left lung base. There is no pleural effusion. Visualized +heart and pericardium reveal no pericardial effusion. +The liver, spleen, pancreas, and adrenal glands are +unremarkable. Multiple +rounded hypodensities in bilateral kidneys are stable, likely +reflecting renal cysts. Patient is status post cholecystectomy. +The stomach and small bowel are unremarkable. There is +diverticulosis of the colon, without evidence of diverticulitis. +There is no evidence of acute inflammation, or secondary signs +to suggest +mesenteric ischemia. Evaluation of the intra-abdominal +vasculature reveals +moderate diffuse atherosclerotic calcification involving the +abdominal aorta, not significantly changed from prior study. +There is mild atherosclerosis at the origin of the celiac axis. +Otherwise, celiac axis, superior mesenteric artery, and inferior +mesenteric artery and their branches appear patent and +unremarkable. +There is no free air, free fluid, or pathologic adenopathy. + +CT OF THE PELVIS WITH IV CONTRAST: Urinary bladder, rectum, and +prostate are unremarkable. There is no pelvic lymphadenopathy or +free fluid. + +OSSEOUS STRUCTURES: Patient status post total right hip +replacement. No +suspicious lytic or sclerotic lesions identified. + +IMPRESSION: No acute intra-abdominal process identified. The +celiac axis, +SMA, and [**Female First Name (un) 899**] appear patent without thrombosis or occlusion. No +secondary +signs to suggest mesenteric ischemia identified. +. +[**2140-10-26**] L-SPINE (AP & LAT) +FINDINGS: There is a levocurvature of the mid lumbar spine. +Multilevel +anterior osteophytes are noted. The disc spaces appear largely +preserved +aside from the scoliosis. Extensive vascular calcifications are +noted. There is a right hip total arthroplasty, partially +visualized. + +IMPRESSION: Multilevel degenerative changes as detailed. +. +[**2140-10-26**] Gastric mucosal biopsies +A. Body: Focal active gastritis; [**Doctor Last Name 6311**] stain shows no +definite helicobacter-like organisms with satisfactory control. +B. Antrum: No diagnostic abnormalities recognized. + +Brief Hospital Course: +#Acute gastritis - The patient was admitted to the ICU overnight +for observation given reported hypotension prior to admission. +Blood pressure was readily fluid-responsive and the patient +remained hemodynamically stable. Melena resolved after admission +and hematocrit remained stable, obviating the need for blood +transfusion. He was treated with PPI gtt in the ICU which was +changed to PPI [**Hospital1 **] on the floor. The patient [**Hospital1 1834**] EGD +showing erosive gastritis and Barrett's esophagus but no active +bleeding. Continued to hold coumadin. Aspirin was restarted in +the setting of [**Hospital1 **] PPI and carafate therapy which will be +continued after discharge at the recommendation of the +consulting GI team. He will follow up in [**Hospital **] clinic, in part to +schedule surveillance endoscopy for the monitoring of Barrett's. + +. +#Candidal esophagitis - EGD also revealed candidal esophagitis +which had been present on endoscopy 6 months prior and perhaps +inadequately treated with a 10-day course of fluconazole. HIV Ab +test was negative at that time. A 3-week course of oral +fluconazole was started with LFT's to be rechecked 1 week after +discharge. He was counseled regarding the proper use of his +corticosteroid inhalers including rinsing thoroughly after use. +. +#C. difficile colitis - The patient was started on a 2 week +course of flagyl. He was placed on contact precautions. [**Name2 (NI) **] was +counseled not to drink alcohol while taking metronidazole. +. +#Abdominal/back pain - This pain reportedly had been present for +several years but had subacutely worsened over the past [**6-23**] +months. Paraspinal muscle tenderness on examination was +suggestive of musculoskeletal pathology. CTA abd/pelvis showed +sigmoid diverticulosis but no evidence of mesenteric ischemia or +AAA. Lumbar plain film showed only chronic degenerative changes +but no compression deformity or lytic lesion. Stable hematocrit +made a RP bleed unlikely. Urinalysis, LFT's, calcium, and +SPEP/UPEP were normal. Pain was well-controlled with tylenol. +. +#Chronic systolic CHF - The patient appeared euvolemic without +signs or symptoms of acute CHF. ACEi had been discontinued prior +to admission due to hypotension. He will continue on +beta-blocker, digoxin, and diuretic therapy after discharge. +. +#Atrial fibrillation - Coumadin was held due to recurrent UGIB, +as above. Aspirin was continued. He was encouraged to follow up +with his cardiologist as soon as possible. +. +#Chronic kidney disease stage III - Creatinine remained at +baseline. Medications were dosed accordingly. +. +#Hyperlipidemia - Continued statin. +. +#Hypothyroidism - Continued levothyroxine. +. +#Asthma - Continued home regimen with counseling regarding +proper use of steroid inhalers, as above. +. +#Nutrition - Heart-healthy diet. +. +#Propylaxis - Pneumoboots, PPI + +Medications on Admission: +Sotalol 80 mg PO BID +Atorvastatin 20 mg PO DAILY +Donepezil 5 mg PO HS +Citalopram 40 mg 1.5 Tab PO DAILY +Quetiapine 25 mg Tab PO TID +Clonazepam 0.5 mg Tablet 1 Tablet PO TID PRN anxiety +Digoxin 62.5 mcg PO DAILY +K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal 1 Tab PO daily +Levothyroxine 112 mcg Tablet 1 Tablet PO DAILY +Trazodone 50 mg Tablet 1 PO HS +Mexiletine 150 mg Capsule 1 Capsule PO Q8H +Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H +Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation [**Hospital1 **] +NitroQuick 0.4 mg Tablet, Sublingual Sig: One (1) Sublingual as +needed as needed for chest pain +Magnesium Oxide 400 mg Tablet 1 Tablet PO daily +Pantoprazole 40 mg Tablet 1 tab Q 12 +Aspirin 81 mg Tablet PO DAILY +Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY +Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] +Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO TID/PRN nausea +Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr po +daily +Furosemide 80 mg Tablet PO daily + +Discharge Medications: +1. Fluconazole 100 mg Tablet Sig: One (1) Tablet PO Q24H (every +24 hours) for 11 days: Through Wednesday, [**11-9**]. +Disp:*11 Tablet(s)* Refills:*0* +2. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 11 days: Through Wednesday, [**11-9**]. +Disp:*33 Tablet(s)* Refills:*0* +3. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Citalopram 40 mg Tablet Sig: 1.5 Tablets PO once a day. +6. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at bedtime) +as needed for insomnia. +7. Quetiapine 25 mg Tablet Sig: Two (2) Tablet PO QAM (once a +day (in the morning)). +8. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO NOON (At +Noon). +9. Quetiapine 25 mg Tablet Sig: Three (3) Tablet PO HS (at +bedtime). +10. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO QID (4 times +a day). +Disp:*120 Tablet(s)* Refills:*0* +11. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +12. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +13. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +14. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) INH Inhalation [**Hospital1 **] (2 times a day). +15. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +every 4-6 hours as needed for shortness of breath or wheezing. +16. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 +hours) as needed for nausea. +17. Klonopin 0.5 mg Tablet Sig: One (1) Tablet PO three times a +day as needed for anxiety. +18. Digoxin 125 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +19. Aspirin EC 81 mg Tablet, Delayed Release (E.C.) Sig: One (1) +Tablet, Delayed Release (E.C.) PO once a day. +20. Donepezil 5 mg Tablet Sig: One (1) Tablet PO at bedtime. +21. Toprol XL 50 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO at bedtime. +22. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +23. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +24. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +25. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +26. GlycoLax 17 gram (100 %) Powder in Packet Sig: One (1) +packet PO once a day. +27. Nitrostat 0.3 mg Tablet, Sublingual Sig: One (1) tablet +Sublingual three times a day as needed for chest pain: Take up +to 3 tablets 5 minutes apart as needed for chest pain and seek +immediate medical attention. +28. Outpatient Lab Work +Please check chemistries and liver function tests on [**Hospital1 766**], +[**11-7**] and fax the results to the office of Dr. [**First Name8 (NamePattern2) **] +[**Last Name (NamePattern1) 26894**] at [**Telephone/Fax (1) 16236**]. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Primary +1) Acute blood loss anemia +2) Acute gastritis +3) Candidal esophagitis +4) Clostridium difficile colitis + +Secondary +1) Coronary artery disease +2) Chronic systolic heart failure +3) Atrial fibrillation +4) Chronic kidney disease stage III +5) Hypothyroidism + + +Discharge Condition: +asymptomatic with stable vital signs. + + +Discharge Instructions: +You were admitted to the hospital with dark stools, likely from +erosions and inflammation in the lining of the stomach seen on +upper endoscopy. Your coumadin (warfarin) was discontinued due +to recurrent bleeding. Continue taking aspirin daily as +prescribed. Take protonix 2 times daily and a new medication +carafate (sucralfate) 4 times daily to help heal and protect the +stomach lining. + +Upper endoscopy also showed a fungal infection in the esophagus +which was partially treated with an antifungal medication. +Please continue taking Fluconazole through Tuesday, [**11-15**]. Please have blood drawn for chemistries and liver function +tests on [**Month (only) 766**], [**11-7**] and ensure that the results are +faxed to Dr. [**Last Name (STitle) 26895**] office at [**Telephone/Fax (1) 16236**]. + +You were diagnosed with a bacterial infection in the large +intestine which was partially treated with an antibiotic +medication. Please continue Flagyl (metronidazole) as prescribed +through Wednesday, [**11-9**]. Do not drink alcohol while +taking this medication due to the risks of side effects from +this combination. + +You no longer need to use the fluticasone inhaler if you are +also using advair. Please be sure to rinse out your mouth and +throat after using this medication to help prevent infection. + +Please continue taking your other medications as prescribed. + +Please adhere to a diet with less than 2 grams of sodium daily. +Please weight yourself daily and call your physician if your +weight increases by greater than 3 lbs. + +Please call the office of Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 26894**] at [**Telephone/Fax (1) 3329**] to +arrange a follow up appointment in 1 week. + +Please call the office of Dr. [**First Name8 (NamePattern2) 449**] [**Last Name (NamePattern1) 437**] at [**Telephone/Fax (1) 62**] to +arrange a follow up appointment in [**1-13**] weeks. + +Please follow up with Dr. [**First Name4 (NamePattern1) 636**] [**Last Name (NamePattern1) 1407**] on Friday, [**11-4**] at +1:00. The office phone number is [**Telephone/Fax (1) 463**]. + +Please call your physician or return to the Emergency Department +if you experience fever, chills, sweats, dizziness, +lightheadedness, difficulty or pain with swallowing, chest pain, +palpitations, shortness of breath, cough, abdominal pain, +vomiting, diarrhea, bloody or black stools, or leg swelling or +pain. + +Followup Instructions: +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 21795**], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2140-11-4**] 1:00 +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2140-11-25**] +8:40 +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 59**] Date/Time:[**2140-12-19**] +1:00 + + + [**Name6 (MD) 251**] [**Name8 (MD) **] MD [**MD Number(1) 910**] + +Completed by:[**2140-10-30**]",151,2140-10-23 15:20:00,2140-10-30 14:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN;TELEMETRY;MELENA," +#acute gastritis - the patient was admitted to the icu overnight +for observation given reported hypotension prior to admission. +blood pressure was readily fluid-responsive and the patient +remained hemodynamically stable. melena resolved after admission +and hematocrit remained stable, obviating the need for blood +transfusion. he was treated with ppi gtt in the icu which was +changed to ppi [**hospital1 **] on the floor. the patient [**hospital1 1834**] egd +showing erosive gastritis and barretts esophagus but no active +bleeding. continued to hold coumadin. aspirin was restarted in +the setting of [**hospital1 **] ppi and carafate therapy which will be +continued after discharge at the recommendation of the +consulting gi team. he will follow up in [**hospital **] clinic, in part to +schedule surveillance endoscopy for the monitoring of barretts. + +. +#candidal esophagitis - egd also revealed candidal esophagitis +which had been present on endoscopy 6 months prior and perhaps +inadequately treated with a 10-day course of fluconazole. hiv ab +test was negative at that time. a 3-week course of oral +fluconazole was started with lfts to be rechecked 1 week after +discharge. he was counseled regarding the proper use of his +corticosteroid inhalers including rinsing thoroughly after use. +. +#c. difficile colitis - the patient was started on a 2 week +course of flagyl. he was placed on contact precautions. [**name2 (ni) **] was +counseled not to drink alcohol while taking metronidazole. +. +#abdominal/back pain - this pain reportedly had been present for +several years but had subacutely worsened over the past [**6-23**] +months. paraspinal muscle tenderness on examination was +suggestive of musculoskeletal pathology. cta abd/pelvis showed +sigmoid diverticulosis but no evidence of mesenteric ischemia or +aaa. lumbar plain film showed only chronic degenerative changes +but no compression deformity or lytic lesion. stable hematocrit +made a rp bleed unlikely. urinalysis, lfts, calcium, and +spep/upep were normal. pain was well-controlled with tylenol. +. +#chronic systolic chf - the patient appeared euvolemic without +signs or symptoms of acute chf. acei had been discontinued prior +to admission due to hypotension. he will continue on +beta-blocker, digoxin, and diuretic therapy after discharge. +. +#atrial fibrillation - coumadin was held due to recurrent ugib, +as above. aspirin was continued. he was encouraged to follow up +with his cardiologist as soon as possible. +. +#chronic kidney disease stage iii - creatinine remained at +baseline. medications were dosed accordingly. +. +#hyperlipidemia - continued statin. +. +#hypothyroidism - continued levothyroxine. +. +#asthma - continued home regimen with counseling regarding +proper use of steroid inhalers, as above. +. +#nutrition - heart-healthy diet. +. +#propylaxis - pneumoboots, ppi + + ","PRIMARY: [Other specified gastritis, with hemorrhage] +SECONDARY: [Intestinal infection due to Clostridium difficile; Candidal esophagitis; Chronic systolic heart failure; Acute posthemorrhagic anemia; Congestive heart failure, unspecified; Atrial fibrillation; Long-term (current) use of anticoagulants; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Other and unspecified hyperlipidemia; Aortocoronary bypass status; Esophageal reflux; Unspecified acquired hypothyroidism; Chronic kidney disease, Stage III (moderate); Other specified forms of chronic ischemic heart disease; Asthma, unspecified type, unspecified; Automatic implantable cardiac defibrillator in situ; Aortic valve disorders; Barrett's esophagus; Diverticulosis of colon (without mention of hemorrhage); Unspecified analgesic and antipyretic causing adverse effects in therapeutic use]" +10774,130230.0,8552,2140-10-18,8551,146298.0,2140-09-12,Discharge summary,"Admission Date: [**2140-9-7**] Discharge Date: [**2140-9-12**] + +Date of Birth: [**2068-2-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 30062**] +Chief Complaint: +melana, chest pain + +Major Surgical or Invasive Procedure: +Esophagogastroduodenoscopy + + +History of Present Illness: +72 year old male with CAD s/p CABG, atrial fib on coumadin, s/p +VT/VF arrest with BiV pacer; CHF with EF 15% admitted to the +MICU ([**9-7**]) after presenting with CP, SOB, abdominal pain, +melena, INR of 3, and Hct drop from 40 to 37. He was admitted to +the MICU where he was given FFP and 1u PRBCs and ruled out for +ACS. He was seen by GI, Surgery, and Cardiology. GI c/s resulted +in plan for EGD. Surgery c/s resulted in INR reversal and serial +exams and hcts. Cardiology felt the patient's CP was not [**2-13**] a +cardiac etiology. He was ruled out for MI regardless. His Hct +was 31 at its lowest but remained stable and, as he was stable +overall, he was felt appropriate for transfer to the floor for +further work up of his melena. +. +Of note, last [**Month (only) 547**], the patient had a similar presentation and +EGD, c-scope, and capsule endoscopy demonstrated gastritis, +Barrett's, diverticulosis and grade 1 hemorrhoids were found, +without any active bleeding. +At time of transfer, the patient endorsed mild abdominal pain +and diaphoresis. He denied chest pain. He had not had a BM in 2 +days. + + +Past Medical History: +--CAD status post CABG with simultaneous aortic aneurysm repair +in [**2133**], history of stenting of the left circumflex artery [**2135**] + +--s/p VT/VF arrest, s/p ICD placement in [**2135**] +--Ischemic cardiomyopathy with an ED of 20%, s/p BiV pacer [**10-18**] + +--Chest wall cellulitis over pacer site [**3-19**] vs. ICD pacer +pocket infection +--PAF +--CKD with baseline Cr. 1.6-2 +--Hyperlipidemia +--Asthma +--Anxiety +--Alzheimer's dementia +--Hypothyroidism +--GI bleed of unknown etiology [**2138**]. EGD revealed esophagitis, +Barrett's esophagus, and duodenitis. No ulcers. +--Diverticulosis +--GERD +--S/P Cholecystectomy + +Social History: +Patient originally from [**Country 4754**] and moved to the United States +in [**2089**]. Worked as an off-set printer in [**Location (un) 686**], where he +continues to live with his wife. Father of five children. +Retired 6 years ago, and since his recent heart problems, says +he rarely leaves the house. Most of his time is spent in front +of the television with his wife handling their affairs at home. +No history of smoking, past or present. Patient was a heavy +drinker until 20 years ago, when he stopped completely after +attending AA and encountering marital difficulties. No history +of illicit drug use. + + +Family History: +Non-contributory. + +Physical Exam: +Afebrile, 115/69, 75, 18, 99%2L +General Appearance: Pleasant, obese male, mildly diaphoretic +lying in bed in no acute distress. +Eyes / Conjunctiva: PERRL, EOMI, no icterus +Head, Ears, Nose, Throat: NCAT, MMMI, JVD 10cm +Cardiovascular: paced, [**3-17**] looud blowing systolic murmur loudest +at LUSB with radiation along the left sternal border throughout, +large, prolonged and displaced PMI +Respiratory / Chest: CTA b/l +Abdominal: Soft, mild guarding, +BS, subumbilical tenderness +with mild tenderness in bl lower quadrents, no guarding +Extremities: pneumoboots in place, dps 1+ bl +Neurologic: Attentive, Follows simple commands, a and o times 3, +movement and sensation intact in all extremities + + + + +Pertinent Results: +[**2140-9-7**] 03:20PM PT-29.2* PTT-31.4 INR(PT)-3.0* +[**2140-9-7**] 03:20PM PLT COUNT-168 +[**2140-9-7**] 03:20PM NEUTS-75.5* LYMPHS-13.8* MONOS-7.0 EOS-3.4 +BASOS-0.4 +[**2140-9-7**] 03:20PM WBC-8.6 RBC-4.30* HGB-12.4* HCT-37.0* MCV-86 +MCH-28.8 MCHC-33.5 RDW-14.6 +[**2140-9-7**] 03:20PM DIGOXIN-0.9 +[**2140-9-7**] 03:20PM CALCIUM-9.0 PHOSPHATE-3.1 MAGNESIUM-2.3 +[**2140-9-7**] 03:20PM CK-MB-4 +[**2140-9-7**] 03:20PM cTropnT-0.01 +[**2140-9-7**] 03:20PM LIPASE-44 +[**2140-9-7**] 03:20PM ALT(SGPT)-20 AST(SGOT)-28 CK(CPK)-112 ALK +PHOS-89 TOT BILI-0.2 +[**2140-9-7**] 03:20PM estGFR-Using this +[**2140-9-7**] 03:20PM GLUCOSE-72 UREA N-23* CREAT-1.7* SODIUM-138 +POTASSIUM-4.5 CHLORIDE-101 TOTAL CO2-32 ANION GAP-10 +[**2140-9-7**] 03:32PM K+-4.6 +[**2140-9-7**] 03:32PM COMMENTS-GREEN TOP +[**2140-9-7**] 06:02PM HCT-35.6* +[**2140-9-7**] 06:12PM LACTATE-0.9 +[**2140-9-7**] 11:30PM HCT-31.1* +[**2140-9-7**] 11:30PM URINE HOURS-RANDOM UREA N-377 CREAT-52 +SODIUM-50 +[**2140-9-7**] 11:30PM DIGOXIN-0.8* +[**2140-9-7**] 11:30PM MAGNESIUM-2.0 +[**2140-9-7**] 11:30PM CK-MB-4 cTropnT-0.01 +[**2140-9-7**] 11:30PM CK(CPK)-110 +[**2140-9-7**] 11:30PM GLUCOSE-89 UREA N-20 CREAT-1.6* SODIUM-141 +POTASSIUM-4.2 CHLORIDE-104 TOTAL CO2-30 ANION GAP-11 + +EKG - [**9-7**]: Ventricular paced rhythm +Atrial mechanism uncertain - may be paced ot possible ectopic +atrial rhythm +Since previous tracing of [**2140-4-19**], ventricular ectopy absent and +P wave +morphology appears changed + +CXR - [**9-7**]: SINGLE PORTABLE UPRIGHT VIEW OF THE CHEST: The +cardiomediastinal contour is +unchanged, with moderate cardiomegaly. There is no pleural +effusion or +evidence of focal consolidation. The dual-lead pacing device is +unchanged in appearance. Osseous structures are unremarkable. +IMPRESSION: No significant change since [**2140-4-12**]. No evidence +of pneumonia or congestive heart failure. + +KUB - [**9-9**]: FINDINGS: There is non-specific bowel gas in the +abdomen. There are no distended loops of bowel, or concerning +air-fluid levels. There is air in the rectum. There is a large +amount of feces in the descending colon, suggesting +constipation. Of note, there is a right hip hemiarthroplasty +hardware, without apparent hardware complication. There is a +mild lumbar levoscoliosis. There are surgical clips at the right +upper quadrant, from prior cholecystectomy. There are wires +projected on to the heart, likely pacer wires. +IMPRESSION: No evidence of bowel obstruction. Likely +constipation. + +EGD - [**9-9**]: Barrett's Exophagitis, Gastritis, Duodenitis + + +Brief Hospital Course: +72 year old male with CAD s/p CABG, atrial fib on coumadin, s/p +VT/VF arrest now with BiV pacer; CHF with EF 15% who presented +with what appears to be non-cardiac chest pain, abdominal pain +and melena. +. +# Melena/Abdominal pain: HCT decreased to 31 from BL of 33 on +arrival to MICU. INR was reversed. Serial hematocrits were +checked and remained stable despite the patient remaining guiac +positive. Aspirin and Coumadin were held until after EGD at +which time they were restarted. IV PPI was given until EGD. +Patient was converted to PO PPI [**Hospital1 **] and instructed to continue +as such for six weeks. GI follow up [**Hospital1 1988**]. Patient had +similar episode in [**4-19**] and had an extensive GI workup which was +negative. +. +# Chest Pain: Pain resolved by the time the patient arrived to +the floor. Cardiology felt the pain was unlikely to be cardiac +in nature as cardiac enzymes were negative on arrival to the ED +after 5 hours of constant chest pain. Pain could be esophageal +as patient has history of Esophagitis and Barretts esophagus. +Last possibility is aortic chest pain as patient has history of +thoracic aortic aneurysm repair, small concern for dissection +although unlikely as patient remained stable throughout his +hopitalization and his CP resolved. +. +# CAD: Patient is s/p CABG. Chest pain unlikely to be cardiac. +MI ruled out. ASA, BB and statin were initially held in setting +of possible GIB but were restarted prior to discharge. +. +# CHF: Patient with history of ischemic CMP with EF 15%. Home +Lasix, Aldactone, and Toprol were intially held but reintroduced +prior to discharge. Home digoxin was continued. +. +# PAF: Patient s/p BiV pacer placement on Coumadin. INR was +reversed intially but coumadin was restarted prior to discharge. +Digoxin was continued. +. +# VF/VT arrest: Patient is s/p BiV pacer/ICD placement. Home +Sotalol, Mexiletine were continued. +. +# Asthma: Albuterol MDI at home. Albuterol Nebs were given PRN. +. +# Hypothyroidism: Home levoxyl was continued. +. +# CKD: Patient with Cr of 1.7 on admission with Baseline Cr +1.5-2. Remained stable. +. +# Alzheimer??????s: Held home Donepezil, Celexa initially. Restarted +prior to discharge. + +Medications on Admission: +Sotalol 80mg [**Hospital1 **] + +Lipitor 20mg daily + +Donepezil 5mg daily + +Quetiapine 25mg, 3tabs qAM, 1tab noon, 3tabs qHS + +Celexa 60mg daily + +Protonix 40mg daily + +ASA 81mg daily + +Clonazepam 0.5mg TID PRN + +Lisinopril 5mg daily + +Digoxin 125mcg, [**1-13**] tab daily + +K-Dur daily + +Spironolactone 25mg daily + +Levothyroxin3e 112mcg daily + +Trazodone 25mg qHS + +Mexiletine 150mg TID + +Albuterol MDI 2puf q6hPRN + +Fluticasone 110mcg 2puff [**Hospital1 **] + +Toprol SL 50mg daily + +Lasix 40mg TID + +Coumadin + + +Discharge Medications: +1. Sotalol 80 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +2. Mexiletine 150 mg Capsule Sig: One (1) Capsule PO Q8H (every +8 hours). +3. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +5. Digoxin 125 mcg Tablet Sig: [**1-13**] Tablet PO DAILY (Daily). +6. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at bedtime) +as needed. +7. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours): +Take twice per day for a total of 6 weeks. Can then resume once +per day. +Disp:*45 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +8. Warfarin 1 mg Tablet Sig: 2-3 Tablets PO once a day: 2 to 3 +tablets by mouth once per day or as directed. +9. Albuterol 90 mcg/Actuation Aerosol Sig: Two (2) puffs +Inhalation every six (6) hours as needed for shortness of breath +or wheezing. +10. Lipitor 20 mg Tablet Sig: One (1) Tablet PO once a day. +11. Celexa 40 mg Tablet Sig: 1.5 Tablets PO once a day. +12. Donepezil 5 mg Tablet Sig: One (1) Tablet PO at bedtime. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Two (2) puffs +Inhalation twice a day. +14. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +15. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO once a day. +16. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +17. Miralax 100 % Powder Sig: One (1) packet PO once a day. +18. K-Dur 20 mEq Tab Sust.Rel. Particle/Crystal Sig: One (1) Tab +Sust.Rel. Particle/Crystal PO once a day. +19. Quetiapine 25 mg Tablet Sig: Two (2) Tablet PO qam. +20. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO qnoon. +21. Quetiapine 25 mg Tablet Sig: Three (3) Tablet PO at bedtime. + +22. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO once a day. +23. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO once a day. +24. Magnesium Oxide 400 mg Tablet Sig: One (1) Tablet PO once a +day. +25. Promethazine 12.5 mg Tablet Sig: 1-2 Tablets PO every six +(6) hours as needed for nausea. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Upper GastroIntestinal Bleed +Barrett's Esophagitis +Gastritis +Duodenitis + +Discharge Condition: +Fair + + +Discharge Instructions: +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +Adhere to 2 gm sodium diet +Fluid Restriction: 2L + +You were admitted to the hospital because you had blood in your +stool along with a decrease in your blood count/hematocrit +concerning for ongoing bleeding. Because you also had chest pain +upon presentation, you were also admitted to rule out the +possibility that you were experiencing a heart attack. + +You had an EGD performed which showed irritation and +inflammation of your esophagus, stomach, and duodenum. This +irritation could be the cause of your bloody stool and decrease +in blood count. You were given blood replacement products along +with high doses of protonix and your blood count remained +stable. You should continue to take you protonix twice per day +for the next 6 weeks. You have follow up with the GI doctors +[**Name5 (PTitle) 1988**]. + +You should call your doctor and/or return to the emergency room +if you have dark tarry stools or bright red blood in your stool, +Chest Pain, Shortness of Breath, or any other corncerning +symptoms. + +Followup Instructions: +[**9-14**] at 9:30am DEVICE CLINIC (Phone:[**Telephone/Fax (1) 59**]) + +[**9-14**] at 10:00am [**First Name8 (NamePattern2) 1903**] [**Last Name (NamePattern1) 1904**], NP (Phone:[**Telephone/Fax (1) 62**]) + +[**9-30**] at 11:00 [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD (Phone:[**Telephone/Fax (1) 463**]) + + + +",36,2140-09-07 21:07:00,2140-09-12 17:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN," +72 year old male with cad s/p cabg, atrial fib on coumadin, s/p +vt/vf arrest now with biv pacer; chf with ef 15% who presented +with what appears to be non-cardiac chest pain, abdominal pain +and melena. +. +# melena/abdominal pain: hct decreased to 31 from bl of 33 on +arrival to micu. inr was reversed. serial hematocrits were +checked and remained stable despite the patient remaining guiac +positive. aspirin and coumadin were held until after egd at +which time they were restarted. iv ppi was given until egd. +patient was converted to po ppi [**hospital1 **] and instructed to continue +as such for six weeks. gi follow up [**hospital1 1988**]. patient had +similar episode in [**4-19**] and had an extensive gi workup which was +negative. +. +# chest pain: pain resolved by the time the patient arrived to +the floor. cardiology felt the pain was unlikely to be cardiac +in nature as cardiac enzymes were negative on arrival to the ed +after 5 hours of constant chest pain. pain could be esophageal +as patient has history of esophagitis and barretts esophagus. +last possibility is aortic chest pain as patient has history of +thoracic aortic aneurysm repair, small concern for dissection +although unlikely as patient remained stable throughout his +hopitalization and his cp resolved. +. +# cad: patient is s/p cabg. chest pain unlikely to be cardiac. +mi ruled out. asa, bb and statin were initially held in setting +of possible gib but were restarted prior to discharge. +. +# chf: patient with history of ischemic cmp with ef 15%. home +lasix, aldactone, and toprol were intially held but reintroduced +prior to discharge. home digoxin was continued. +. +# paf: patient s/p biv pacer placement on coumadin. inr was +reversed intially but coumadin was restarted prior to discharge. +digoxin was continued. +. +# vf/vt arrest: patient is s/p biv pacer/icd placement. home +sotalol, mexiletine were continued. +. +# asthma: albuterol mdi at home. albuterol nebs were given prn. +. +# hypothyroidism: home levoxyl was continued. +. +# ckd: patient with cr of 1.7 on admission with baseline cr +1.5-2. remained stable. +. +# alzheimer??????s: held home donepezil, celexa initially. restarted +prior to discharge. + + ","PRIMARY: [Hemorrhage of gastrointestinal tract, unspecified] +SECONDARY: [Paroxysmal ventricular tachycardia; Chronic systolic heart failure; Congestive heart failure, unspecified; Other chest pain; Esophageal reflux; Unspecified acquired hypothyroidism; Aortocoronary bypass status; Duodenitis, without mention of hemorrhage; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Asthma, unspecified type, unspecified; Other and unspecified hyperlipidemia; Chronic kidney disease, unspecified; Barrett's esophagus; Unspecified gastritis and gastroduodenitis, without mention of hemorrhage; Long-term (current) use of anticoagulants; Other specified forms of chronic ischemic heart disease; Automatic implantable cardiac defibrillator in situ; Atrial fibrillation]" +11638,122879.0,15382,2179-12-03,15380,133678.0,2179-09-22,Discharge summary,"Admission Date: [**2179-9-16**] Discharge Date: [**2179-9-22**] + +Date of Birth: [**2108-5-29**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1515**] +Chief Complaint: +Hypovolemia + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +71 year old F with PMH significant for advanced ischemic +cardiomyopathy EF 15%, atrial fibrillation with ICD and CKD who +presented to [**Hospital **] hospital [**2179-9-14**] for generalized weakness. +Patient reports gaining fluid (notably abdomen and lower +extremity) since early [**Month (only) 462**] and consequently toresmide was +increased and metolazone started. Per OMR notes patient's +creatinine increased to 4.7, had 15 pound weight loss (177 from +dry weight 190lb), lower blood pressures and was consequently +referred to [**Hospital **] Hospital. Due to weight loss all diuretics +were on hold since [**2179-9-7**]. Patient reports 1 month history of +increasing fatigue, weakness and shortness of breath. Denies +increase in orthopnea, PND. Denies syncope, pre-syncope or +dizziness. Denies chest pain. Denies fever, chills, cough or +increase in urination. +. +Patient's presenting vitals to [**Hospital **] Hospital were temperature +97.1, HR 70, RR 20, blood pressure 78/56. Labs notable for +creatinine of 4.7, Hematocrit 26.1, CBC 2.5, plt 60,000, INR +2.6. She was given 3 units pRBC and 2.5+ L of fluid. Cardiology +was consulted. Patient did not require pressor support. Heme was +consulted for pancytopenia felt to be secondary to hypersplenism +(demonstrated on ultrasound, new since 5/[**2177**]). Patient was +transferred to [**Hospital1 18**] CCU for further care. +. +On review of systems, she denies any prior history of stroke, +TIA, bleeding at the time of surgery, myalgias, joint pains, +cough, hemoptysis, black stools or red stools. She denies recent +fevers, chills or rigors. She denies exertional buttock or calf +pain. All of the other review of systems were negative + + +Past Medical History: +1. ischemic cardiomyopathy (EF 10-25%) s/p BiV ICD +2. Coronary artery disease status post PTCA and stenting of the +LAD in [**2164**]. +3. h/o PE secondary to DVT s/p IVC filter +4. Atrial fibrillation status post cardioversion and +biventricular pacemaker implantation. +5. HTN +6. Obesity +7. PVD +8. small VSD +9. hypothyroidism +PAST MEDICAL HISTORY: +1. CARDIAC RISK FACTORS: + Dyslipidemia +2. CARDIAC HISTORY: +-Ischemic cardiomyopathy EF %15-20 s/p biv ICD +-CAD s/p post PTCA and stenting of the LAD in [**2164**]. +-CABG: None +-PACING/ICD: atrial fibrillation on anticoagulation and ICD +biventricular pacemaker +3. OTHER PAST MEDICAL HISTORY: +chronic kidney disease +bilateral DVT s/[**Initials (NamePattern4) **] [**Last Name (NamePattern4) **] filter +pulmonary embolism +osteoarthritis +hyperkalemia + + +Social History: +Pt lives alone. She is not married. She reports a 20 pack year +history, however she quit 30 yrs ago. Denies EtOH or illicit +drug use. + + +Family History: +Mother had MI at age 50. Father in good health. Maternal uncle +died of MI in his 50's. + +Physical Exam: +Gen: alert, talkative, NAD +HEENT: supple, no LAd, Pos JVD at 12 cm +CV: RRR, 2/6 systolic murmur at apex +RESP: CTAB, no crackles or wheezes +ABD: distended, soft, pos fluid wave, umbilical hernia, +EXTR: 1+ edema bilat. right > L +NEURO: alert, oriented, +Extremeties: Groin +Pulses: + +Right: DP 1+ PT 1+ +Left: DP 1+ PT 1+ +Skin: intact +Access: PIV +Tubes: Foley d/c'ed. + + +Pertinent Results: +[**2179-9-22**] 06:50AM BLOOD WBC-3.8* RBC-3.30* Hgb-10.8* Hct-31.7* +MCV-96 MCH-32.7* MCHC-34.0 RDW-17.1* Plt Ct-95* +[**2179-9-16**] 10:40PM BLOOD Neuts-86.4* Lymphs-8.9* Monos-3.3 Eos-1.0 +Baso-0.4 +[**2179-9-22**] 06:50AM BLOOD Plt Ct-95* +[**2179-9-22**] 06:50AM BLOOD Glucose-91 UreaN-83* Creat-2.3* Na-135 +K-4.5 Cl-99 HCO3-27 AnGap-14 +. +CXR [**9-17**]: +AP chest compared to [**2175-9-20**]: + Severe cardiomegaly has progressed. Lungs are clear. Pulmonary +and +mediastinal vasculature are unremarkable and there is no pleural +effusion. +Transvenous right atrial and left ventricular pacer leads and +right +ventricular pacer defibrillator lead are unchanged in their +respective +positions. No pneumothorax. + . +Right Leg Ultrasound: [**2179-9-17**] +Grayscale color and Doppler son[**Name (NI) 1417**] of the right common +femoral, +superficial femoral, popliteal, and tibial veins were performed. +There is +normal flow, compression and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the right +leg. +. +Abdominal Ultrasound: [**2179-9-17**] +IMPRESSION: +1. Mild splenomegaly. +2. No thrombus identified within the IVC. +3. Large amount of ascites. + + +Brief Hospital Course: +70 year old female with severe biventricular failure with +profoundly reduced left ventricular ejection fraction of 15%, +moderate mitral regurgitation and tricuspid regurgitation with +moderate pulmonary hypertension presented to outside hospital +for fatigue and hypotension. Transferred to [**Hospital1 18**] for further +treatment of her renal failure and heart failure. +. +# PUMP: Patient with known ischemic cardiomyopathy EF 15%. New +splenomegaly concerning for worsening of EF. On admission, pt +was 7 lbs below her dry weight (190) and with poor renal +function therefore there was some concern for over-diuresis. +Gentle IVF was given and pt was allow to re-equilibrate. She +appeared to be perfusing well and did not require ionotropic +support. Her renal function improved over the course of her +stay, as did her edema with PO intake and holding her diuretics. + She was continued on her home cardiac meds including lisinopril +(decreased to 2.5/day), carvedilol and ASA. She will be +discharged on 20 mg toresemide daily for diuresis. Her Fluid +status will need to be monitored very closely as she is quite +fragile. Daily weights will need to be monitored and as her +wieght increases, she will need to have more diuretics added on. +Please contact [**Name (NI) **] [**Last Name (NamePattern1) **] NP, her heart failure NP for +further management at [**Telephone/Fax (1) 62**]. +. +# RHYTHM: Mrs [**Known lastname **] is AV paced with right bundle branch +block with underlying A Fib. She was treated with coumadin, +amiodarone and carvedilol. Her coumadin was decreased on +discharge for elevated INR, and she will follow up for repeat +INR and warfarin adjustment. She was seen by EP for evaluation +of her pacer settings, however adjustments were deferred to the +outpatient setting as changes need to be done under echo, +therefore she has an appointment scheduled this month for +adjustment of pacer settings. +. +# CORONARIES: One vessel coronary artery disease with patent +prior LAD stent. Last cath [**2171**]. No chest pain during this +admission. ASA, carvedilol and statin were continued. +. +# Acute on chronic renal failure: Her baseline creatinine is +1.3-2, during this visit creatinine peaked at 3.2 and was +thought to be pre-renal in the setting of over-diuresis. Her +renal function improved with diuretics and encouraging PO +intake. +. +# Pancytopenia: Heme consulted at OSH - felt to be secondary to +splenomegaly secondary to CHF. Platelets were stable during +this admission. Would recommend following as an outpatient with +hematology. +. +# Asymmetric lower extremity swelling: Right > Left. LENI OSH +negative. Patient reports no recent instrumentation. This was +felt to be a chronic issue related to positioning as it is no +worse than baseline and the patient tends to lie primarily on +her right side. +. +# Hypothyroid: Her levothyroxine was continued at outpatient +doses. +. +# LE muscle spasm +Not a [**Last Name **] problem, pt states started about mid [**Month (only) **]. +Interfering with activity, not able to walk now and is assist of +two to chair. Unclear how much hospitalization and +deconditioning are contributing. No improvement with hydration. +Electolytes WNL. Pt was started on Ca and will follow-up as an +outpatient. Dr. [**Last Name (STitle) **], a neurologist from [**Location (un) **] has been +contact[**Name (NI) **] to see the pt as soon as possible, her sister, will +help with setting this appt up in a timely manner. + +Medications on Admission: +- omeprazole 20 mg po qd +- simvastatin 20mg po qd +- amiodarone 200 mg qd +- carvedilol 25 mg po [**12-18**] tab in am and 1 tab pm +- Levoxyl 112 mg po qd +- recently stopped coumadin, allopurinol, colchecine, +lisinopril, Metolazone 2.5mg twice a week, torsemide 40 mg [**Hospital1 **], +digoxin + + +Discharge Medications: +1. Senna 8.6 mg Tablet Sig: 1-2 Tablets PO BID (2 times a day) +as needed for Constipation. +2. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +4. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain/fever. +6. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +7. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Carvedilol 6.25 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +9. Warfarin 2 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: Pt's home dose is 4mg daily. Please check INR on [**9-24**]. +10. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO TID W/MEALS (3 TIMES A DAY WITH MEALS). +11. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +12. Torsemide 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +this will need to be uptitrated as weight increases over dry +weight. . +13. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +14. Simvastatin 20 mg Tablet Sig: One (1) Tablet PO once a day. + + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital1 599**] of [**Location (un) 1439**] + +Discharge Diagnosis: +Acute on Chronic systolic Congestive Heart Failure +Atrial fibrillation +Acute on chronic Kidney Disease +Pancytopenia +Hx of Bilateral DVT s/p filter + + +Discharge Condition: +stable +weight= 85.4kg. This is pt's dry weight. +BP= 80's-90's/50's. This is pts baseline +HR= 70's. +O2 sat on RA= 97% + + +Discharge Instructions: +You had too much fluid taken off and your kidneys did not +function well. We stopped all of your diuretics and gave you +some intravenous fluid. Your kidney function is now better and +we will restart the Torsemide at a very low dose. You will need +to be followed closely over the next few weeks because you will +need to have more of your medicines restarted. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] is +the CHF NP who follows you on a regular basis. She can be +reached with any questions at [**Telephone/Fax (1) 62**]. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +or 6 pounds in 3 days. +Follow a low sodium (2000mg) diet +Do not drink more than 6 cups of fluid per day or about 1.5 +liters. +We have set up an outpatient appt to see a neurologist about +your muscle spasms. +. +Medication changes: +1. Decrease your Torsemide to 20 mg daily +2. Decrease your Lisinopril to 2.5 mg daily +3. Decrease Warfarin to 2mg daily until your INR is < 3.0, then +increase to 4mg daily. +4. Do not take Colchicine or Allopurinol unless your gout comes +back (you were not taking this at home) +5. START taking Calcium and Vitamin D to prevent osteoporosis. + +Followup Instructions: +Primary Care: +[**Last Name (LF) 44661**],[**First Name3 (LF) 25**] M. Phone: [**Telephone/Fax (1) 44659**] Date/time: Please call for +an appt after you get out of rehabilitation. +Cardiology: +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-9-29**] +10:30 +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-10-6**] +10:00 +. +Provider: [**First Name8 (NamePattern2) 1903**] [**Last Name (NamePattern1) 1904**], [**MD Number(3) 1240**]:[**Telephone/Fax (1) 62**] +Date/Time:[**2179-10-6**] 10:30 +Neurology: +Dr. [**Last Name (STitle) **] Phone: [**Telephone/Fax (1) 44662**] Date/Time: Office will call with +an appt. + + + +Completed by:[**2179-9-22**]",72,2179-09-16 21:42:00,2179-09-22 14:10:00,EMERGENCY,TRANSFER FROM HOSP/EXTRAM,SNF,CONGESTIVE HEART FAILURE," +70 year old female with severe biventricular failure with +profoundly reduced left ventricular ejection fraction of 15%, +moderate mitral regurgitation and tricuspid regurgitation with +moderate pulmonary hypertension presented to outside hospital +for fatigue and hypotension. transferred to [**hospital1 18**] for further +treatment of her renal failure and heart failure. +. +# pump: patient with known ischemic cardiomyopathy ef 15%. new +splenomegaly concerning for worsening of ef. on admission, pt +was 7 lbs below her dry weight (190) and with poor renal +function therefore there was some concern for over-diuresis. +gentle ivf was given and pt was allow to re-equilibrate. she +appeared to be perfusing well and did not require ionotropic +support. her renal function improved over the course of her +stay, as did her edema with po intake and holding her diuretics. + she was continued on her home cardiac meds including lisinopril +(decreased to 2.5/day), carvedilol and asa. she will be +discharged on 20 mg toresemide daily for diuresis. her fluid +status will need to be monitored very closely as she is quite +fragile. daily weights will need to be monitored and as her +wieght increases, she will need to have more diuretics added on. +please contact [**name (ni) **] [**last name (namepattern1) **] np, her heart failure np for +further management at [**telephone/fax (1) 62**]. +. +# rhythm: mrs [**known lastname **] is av paced with right bundle branch +block with underlying a fib. she was treated with coumadin, +amiodarone and carvedilol. her coumadin was decreased on +discharge for elevated inr, and she will follow up for repeat +inr and warfarin adjustment. she was seen by ep for evaluation +of her pacer settings, however adjustments were deferred to the +outpatient setting as changes need to be done under echo, +therefore she has an appointment scheduled this month for +adjustment of pacer settings. +. +# coronaries: one vessel coronary artery disease with patent +prior lad stent. last cath [**2171**]. no chest pain during this +admission. asa, carvedilol and statin were continued. +. +# acute on chronic renal failure: her baseline creatinine is +1.3-2, during this visit creatinine peaked at 3.2 and was +thought to be pre-renal in the setting of over-diuresis. her +renal function improved with diuretics and encouraging po +intake. +. +# pancytopenia: heme consulted at osh - felt to be secondary to +splenomegaly secondary to chf. platelets were stable during +this admission. would recommend following as an outpatient with +hematology. +. +# asymmetric lower extremity swelling: right > left. leni osh +negative. patient reports no recent instrumentation. this was +felt to be a chronic issue related to positioning as it is no +worse than baseline and the patient tends to lie primarily on +her right side. +. +# hypothyroid: her levothyroxine was continued at outpatient +doses. +. +# le muscle spasm +not a [**last name **] problem, pt states started about mid [**month (only) **]. +interfering with activity, not able to walk now and is assist of +two to chair. unclear how much hospitalization and +deconditioning are contributing. no improvement with hydration. +electolytes wnl. pt was started on ca and will follow-up as an +outpatient. dr. [**last name (stitle) **], a neurologist from [**location (un) **] has been +contact[**name (ni) **] to see the pt as soon as possible, her sister, will +help with setting this appt up in a timely manner. + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Acute kidney failure, unspecified; ; Ventricular septal defect; Congestive heart failure, unspecified; Other specified forms of chronic ischemic heart disease; Atrial fibrillation; Right bundle branch block; Mitral valve disorders; Other chronic pulmonary heart diseases; Diseases of tricuspid valve; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Coronary atherosclerosis of native coronary artery; Splenomegaly; Unspecified acquired hypothyroidism; Peripheral vascular disease, unspecified; Obesity, unspecified; Osteoarthrosis, unspecified whether generalized or localized, site unspecified; Spasm of muscle; Swelling of limb; Automatic implantable cardiac defibrillator in situ; Personal history of venous thrombosis and embolism; Percutaneous transluminal coronary angioplasty status; Long-term (current) use of anticoagulants]" +11638,155878.0,15383,2180-01-21,15381,136238.0,2179-11-06,Discharge summary,"Admission Date: [**2179-10-26**] Discharge Date: [**2179-11-6**] + +Date of Birth: [**2108-5-29**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**Last Name (NamePattern1) 1167**] +Chief Complaint: +Increasing Dyspnea + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with LVEF of 10%, atrial fibrillation, [**Hospital1 **]-V ICD, CKD, with past +history of DVT, PE on Coumadin who presents with increasing +dyspnea. The patient was recently discharged from [**Hospital1 18**] CCU on +[**9-22**] for CHF exacerbation and was discharged to rehab facility. +Since that time, patient was hospitalized at [**Location (un) **] two weeks +ago for pneumonia. + +The patient reports that over the past week, the patient has had +increasing dyspnea with exertion. At baseline, patient is unable +to perform ADLs without the assistance of physical therapy. Over +the past week, there has been a noticible worsening in her +physical limitations. The patient recently saw Dr. [**First Name (STitle) 437**] as an +outpatient and had her dose of Torsemide increased from 20mg to +40mg and Carvedilol was discontinued and switched to Metoprolol +tartrate 12.5mg [**Hospital1 **]. + +Patient was taken to [**Hospital **] hospital for initial evaluation and +was given another dose of torsemide 40mg x 1 and then +transferred to [**Hospital1 18**] as her cardiac care is here. Patient's +initial VS in the ED were 98.3 76 105/70 16 96 on 4LNC. Pt was +initially dyspneic, RR in 20s, wheezes bilaterally. Ascities +worse than in past few weeks. 2+ pedal edema. + +Cardiac review of systems is notable for presence of chest pain +at rehab, dyspnea on exertion, paroxysmal nocturnal dyspnea, +orthopnea, ankle edema. No palpitations, syncope or presyncope. + + +Past Medical History: +. ischemic cardiomyopathy (EF 10-25%) s/p BiV ICD +2. Coronary artery disease status post PTCA and stenting of the + +LAD in [**2164**]. +3. h/o PE secondary to DVT s/p IVC filter +4. Atrial fibrillation status post cardioversion and +biventricular pacemaker implantation. +5. HTN +6. Obesity +7. PVD +8. small VSD +9. hypothyroidism +PAST MEDICAL HISTORY: +1. CARDIAC RISK FACTORS: + Dyslipidemia +2. CARDIAC HISTORY: +-Ischemic cardiomyopathy EF %15-20 s/p biv ICD +-CAD s/p post PTCA and stenting of the LAD in [**2164**]. +-CABG: None +-PACING/ICD: atrial fibrillation on anticoagulation and ICD +biventricular pacemaker +3. OTHER PAST MEDICAL HISTORY: +chronic kidney disease +bilateral DVT s/[**Initials (NamePattern4) **] [**Last Name (NamePattern4) **] filter +pulmonary embolism +osteoarthritis +hyperkalemia + + +Social History: +Pt lives alone but currently resides at [**Hospital 599**] rehab. She is not +married. She reports a 20 pack year history, however she quit 30 +yrs ago. Denies EtOH or illicit drug use. + + +Family History: +Mother had MI at age 50. Father in good health. Maternal uncle +died of MI in his 50's. + +Physical Exam: +VS: 99.5, 95/60, 80, 22, 94% 3L NC +GENERAL: NAD. Oriented x3. Mood, affect appropriate. +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. No xanthalesma. + +NECK: Supple with JVP of 15 cm. +CARDIAC: PMI inferolaterally displaced, RR, normal S1, S2. +Holosystolic murmur at apex. +LUNGS: Bilateral rales to mid-lung fields. +ABDOMEN: Soft, distended. + Fluid wave. Mild Hepatomegaly. +Unable to palpate spleen. +EXTREMITIES: +2 BLE edema. RLE > LLE. Warm +SKIN: No stasis dermatitis, ulcers, scars, or xanthomas. +PULSES: +Right: DP 1+ PT 1+ +Left: DP 1+ PT 1+ + +Pertinent Results: +Admission Labs: +[**2179-10-26**] 12:30AM WBC-6.2# RBC-3.60* HGB-11.3* HCT-34.7* MCV-96 +MCH-31.3 MCHC-32.5 RDW-18.6* +[**2179-10-26**] 12:30AM PLT SMR-NORMAL PLT COUNT-182# +[**2179-10-26**] 12:30AM PT-28.4* PTT-36.3* INR(PT)-2.8* +[**2179-10-26**] 12:30AM CK-MB-NotDone proBNP-[**Numeric Identifier 44663**]* +[**2179-10-26**] 12:30AM cTropnT-0.04* +[**2179-10-26**] 12:30AM ALT(SGPT)-51* AST(SGOT)-56* CK(CPK)-62 ALK +PHOS-194* TOT BILI-1.7* +[**2179-10-26**] 12:30AM GLUCOSE-112* UREA N-48* CREAT-1.6* SODIUM-136 +POTASSIUM-4.6 CHLORIDE-97 TOTAL CO2-27 ANION GAP-17 +. +EKG: [**2179-10-26**] 0003: V Paced at 69, w/ RAD, bifascicular block. +. +TTE [**10-26**]: +The left atrium is moderately dilated. The right atrium is +markedly dilated. There is mild symmetric left ventricular +hypertrophy. The left ventricular cavity is moderately dilated. +There is severe regional left ventricular systolic dysfunction +with anterior, septal and apical akinesis, as well as akinesis +of the distal inferior wall (proximal LAD distribution). There +is mild hypokinesis of the remaining segments (LVEF = 15-20%). +No masses or thrombi are seen in the left ventricle. The right +ventricular cavity is moderately dilated with severe global free +wall hypokinesis. The aortic valve leaflets (3) are mildly +thickened but aortic stenosis is not present. Mild to moderate +([**12-18**]+) mitral regurgitation is seen. Severe [4+] tricuspid +regurgitation is seen. There is mild pulmonary artery systolic +hypertension. There is a trivial/physiologic pericardial +effusion. +. +IMPRESSION: Dilated left ventricle with severe regional systolic +dysfunction, c/w an extensive prior LAD infarction. Dilated +right ventricle with severe systolic dysfunction. Mild to +moderate mitral regurgitation. Severe tricuspid regurgitation. +At least mild pulmonary hypertension. +. +Compared with the prior study (images reviewed) of [**2177-5-26**], +severity of tricuspid regurgitation has increased. The other +findings are similar. +. +RLE US [**10-26**]: No right lower extremity DVT. +ABD DOPPLER [**10-26**]: +1. Distended hepatic veins and ascites, the constellation of +findings can be seen in the setting of congestive heart failure. +Otherwise, normal Doppler examination of the liver. +. +2. No evidence of biliary pathology. +. +MYOCARDIAL VIABILITY STUDY [**10-27**]: +Within limitation of current study, fixed defects in distal +anterior +and apical walls are consistent with scarring. Improvement of +inferior wall defect with correction is suggestive of myocardial +viability. +. +LHC/RHC [**11-2**]: +COMMENTS: +1. Selective coronary angiography of this right dominant system +revealed +one vessel coronary artery disease. The LMCA had no +angiographically +apparent disease. The LAD had mild instent restenosis of the +prior +stent. The LCx had no angiographically apparent disease. The RCA +was +occluded and similar to prior. +2. Resting hemodynamics on milrinone therapy revealed moderately + +elevated right and left sided filling pressures with an RVEDP of +15 mmHg +and PCWP of 20 mmHg. There was moderate pulmonary hypertension +with a +PASP of 42/20 mmHg. There was normal systemic blood pressure +with +central pressure of 108/63 mmHg. There was a low-normal cardiac +index of +2.1 L/min/m2. There was no transaortic valve gradient on careful + +pullback from LV to aorta. +3. Peripheral angiography revealed patent renal arteries +bilaterally. +. +FINAL DIAGNOSIS: +1. One vessel coronary artery disease. +2. Moderate biventricular diastolic dysfunction. +3. Moderate pulmonary hypertension. +4. Normal systemic pressure. +5. Low-normal cardiac index. +6. Patent renal arteries. +. +KUB [**11-2**]: +1. There is no ileus or small bowel obstruction. +2. Tubular radiopaque left paraspinal structure of unknown +etiology warrants repeat AP and lateral radiograph. +. + + +Brief Hospital Course: +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with LVEF of 10%-15%, atrial fibrillation, [**Hospital1 **]-V ICD, low cardiac +output state, chronic kidney disease with past history of DVT, +PE on Coumadin. + +#. NYHA Class 4 Systolic congestive Heart Failure, EF 15%. with +severe volume overloaded on examination on admission. She had a +low output state with known low EF and dilated ischemic +cardiomyopathy. It was felt that she would likely need +inotropic support and she was sent to the CCU for diuresis with +milrinone gtt + lasix gtt + metolazone. The patient had +significant diuresis on this regimen. It was felt that if there +was viable myocardium currently hibernating [**1-18**] low perfusion +state, intervention may improve cardiac function. A myocardial +viability study was performed and demonstrated inferior wall +myocardial viability. LHC/RHC were performed but no +intervenable targets were appreciated; additionally, the patient +was thought to be a poor candidate for CABG/TR [**1-18**] poor targets +for grafts. It was therefore felt that the patient could only +be maximized on medical therapy. Diuresis was changed to PO on +[**11-5**] to her precious dose of Torsemide and metolazone was added +daily to regimen. Weight on discharge________. Would follow +lytes every other day until stable and weekly thereafter. + +# C-diff colitis - Positive C. difficile toxin assay. Patient +was started on PO metronidazole and cholesyramine with clinical +improvement as gauged by frequency of diarrhea, fever, and WBC +count. Peak WBC 11.4. Flagyl to be continued x 7 more days. +Once 2 week flagyl course is finished, can consider restarting +immodium for symptomatic relief. + +# UTI - Patient was found to have UTI [**1-18**] Klebsiella pneumoniae, +pansensitive except for intermediate sensitivity to +nitrofurantoin. She was started on ciprofloxacin for 7 day +course, finished on [**11-4**]. + +#. Rhythm: She has a BiV ICD in place and was V-paced on ECG. +She was monitored on telemetry. No events. + +#. Coronaries: Patient with mid-LAD BMS '[**64**]. Trop 0.04, CK-MB +negative that was likely related to CHF exacerbation. She was +continued on a statin and aspirin. + +#. URI: She had been diagnosed with a URI prior to admission and +had been started on Zithromax. This was held in the hospital +and sputum cultures were sent, found to be negative. Pt is +currently asymptomatic. + +#. Asicites: She had significant ascities on exam and she was +s/p 6L tap two weeks ago. It was felt her ascites was likely +related to right-sided heart failure and would be difficult to +resolve with diuretics. She was restarted on her home regimen of +torsemide plus Metolazone as noted above. + +#. LFT abnormalities: She had a mild transaminities with an AP +190, TBili 1.7. It appeared to be obstructive pattern, likely +related to congestive hepatopathy. Resolved prior to discharge. + +#. H/o DVT/PE: She was anticoagulated with Coumadin and has a +[**Location (un) 260**] filter in place. She had a RLE U/S that showed no +DVT. Her INR today is _______. INR should be followed every +other day until stable and weekly thereafter. + +# Hypothyroidism: Continued Levothyroxine. + +# CODE: She was full code during this hospitalization. It is +thought that she is end stage in regard to her CHF with medical +treatment her only option at this time. Palliative care was not +persued during this hospital stay but may be introduced by Dr. +[**First Name (STitle) 437**]/[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] [**MD Number(3) 44664**] continues to have frequent +hospitalizations. + +Medications on Admission: +Allopurinol 100mg daily +Amiodarone 200mg daily +Levothyroxine 125mcg daily +ASA 81mg daily +Zocor 20mg daily +Zithromax 250mg daily (until [**10-26**]) for URI +Torsemide 40mg po BID +Metoprolol Succinate 12.5mg po BID +Digoxin 0.0625 mcg daily +Prilosec 20mg daily +Zinc 220mg po daily +Vit C 500mg po daily +Coumadin 2.5mg daily +Biscacodyl 10mg suppository daily prn for constipation +Milk of Mag 30ml po daily prn for constipation +Melatonin 1mg po qhs prn for insomnia +MVI +Immodium 2mg po 4x daily prn for loose stool + +Discharge Medications: +1. Metolazone 2.5 mg Tablet Sig: One (1) Tablet PO once a day. +2. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +3. Allopurinol 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +6. Digoxin 125 mcg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +7. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO at bedtime. +8. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO DAILY (Daily). +9. Metoprolol Succinate 25 mg Tablet Sustained Release 24 hr +Sig: 0.5 Tablet Sustained Release 24 hr PO twice a day. +10. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) vial Inhalation Q6H (every 6 hours) as +needed for cough/sob. +11. Codeine-Guaifenesin 10-100 mg/5 mL Syrup Sig: 5-10 MLs PO +Q6H (every 6 hours) as needed for cough: Hold for sedation or RR +< 10. +12. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 14 days: last day [**11-20**]. +13. Cholestyramine-Sucrose 4 gram Packet Sig: One (1) PO BID (2 +times a day): Do not give at the same time as Levothyroxine, +metolazone and Digoxin. . +14. Warfarin 2 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: check INR every other day. +15. Torsemide 20 mg Tablet Sig: Two (2) Tablet PO BID (2 times a +day). +16. Metolazone 2.5 mg Tablet Sig: One (1) Tablet PO once a day. + +17. Sodium Chloride 0.65 % Aerosol, Spray Sig: [**12-18**] Sprays Nasal +QID (4 times a day) as needed for dry nose. +18. Heparin Flush (10 units/ml) 2 mL IV PRN line flush +PICC, heparin dependent: Flush with 10mL Normal Saline followed +by Heparin as above daily and PRN per lumen. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital1 599**] Senior Care Center - [**Location (un) 1439**] + +Discharge Diagnosis: +Acute on chronic systolic heart failure +Clostridium difficile colitis +Klebsiella Urinary Tract Infection. + + +Discharge Condition: +Dry weight 100 kg. +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Out of Bed with assistance to chair or +wheelchair + + +Discharge Instructions: +You were seen at [**Hospital1 18**] with heart failure. You were admitted to +the cardiac care unit for diuresis with Milrinone and lasix. + +We are discharging you home on the same heart failure regimen as +you were admitted with and adding metolazone 2.5mg po daily in +the am. + +You were found to have clostridium difficile colitis and were +started on flagyl. You were also found to have a urinary tract +infection and were treated with a seven day course of +ciprofloxacin. + +Weigh yourself every morning, call [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] NP if weight +goes up more than 3 lbs in 1 day or 6 pounds in 3 days. + +Followup Instructions: +Cardiology: +Provider: [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) **] [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-11-22**] +10:00 + + + +",76,2179-10-26 00:33:00,2179-11-06 17:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,CONGESTIVE HEART FAILURE," +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with lvef of 10%-15%, atrial fibrillation, [**hospital1 **]-v icd, low cardiac +output state, chronic kidney disease with past history of dvt, +pe on coumadin. + +#. nyha class 4 systolic congestive heart failure, ef 15%. with +severe volume overloaded on examination on admission. she had a +low output state with known low ef and dilated ischemic +cardiomyopathy. it was felt that she would likely need +inotropic support and she was sent to the ccu for diuresis with +milrinone gtt + lasix gtt + metolazone. the patient had +significant diuresis on this regimen. it was felt that if there +was viable myocardium currently hibernating [**1-18**] low perfusion +state, intervention may improve cardiac function. a myocardial +viability study was performed and demonstrated inferior wall +myocardial viability. lhc/rhc were performed but no +intervenable targets were appreciated; additionally, the patient +was thought to be a poor candidate for cabg/tr [**1-18**] poor targets +for grafts. it was therefore felt that the patient could only +be maximized on medical therapy. diuresis was changed to po on +[**11-5**] to her precious dose of torsemide and metolazone was added +daily to regimen. weight on discharge________. would follow +lytes every other day until stable and weekly thereafter. + +# c-diff colitis - positive c. difficile toxin assay. patient +was started on po metronidazole and cholesyramine with clinical +improvement as gauged by frequency of diarrhea, fever, and wbc +count. peak wbc 11.4. flagyl to be continued x 7 more days. +once 2 week flagyl course is finished, can consider restarting +immodium for symptomatic relief. + +# uti - patient was found to have uti [**1-18**] klebsiella pneumoniae, +pansensitive except for intermediate sensitivity to +nitrofurantoin. she was started on ciprofloxacin for 7 day +course, finished on [**11-4**]. + +#. rhythm: she has a biv icd in place and was v-paced on ecg. +she was monitored on telemetry. no events. + +#. coronaries: patient with mid-lad bms [**64**]. trop 0.04, ck-mb +negative that was likely related to chf exacerbation. she was +continued on a statin and aspirin. + +#. uri: she had been diagnosed with a uri prior to admission and +had been started on zithromax. this was held in the hospital +and sputum cultures were sent, found to be negative. pt is +currently asymptomatic. + +#. asicites: she had significant ascities on exam and she was +s/p 6l tap two weeks ago. it was felt her ascites was likely +related to right-sided heart failure and would be difficult to +resolve with diuretics. she was restarted on her home regimen of +torsemide plus metolazone as noted above. + +#. lft abnormalities: she had a mild transaminities with an ap +190, tbili 1.7. it appeared to be obstructive pattern, likely +related to congestive hepatopathy. resolved prior to discharge. + +#. h/o dvt/pe: she was anticoagulated with coumadin and has a +[**location (un) 260**] filter in place. she had a rle u/s that showed no +dvt. her inr today is _______. inr should be followed every +other day until stable and weekly thereafter. + +# hypothyroidism: continued levothyroxine. + +# code: she was full code during this hospitalization. it is +thought that she is end stage in regard to her chf with medical +treatment her only option at this time. palliative care was not +persued during this hospital stay but may be introduced by dr. +[**first name (stitle) 437**]/[**first name8 (namepattern2) **] [**last name (namepattern1) **] [**md number(3) 44664**] continues to have frequent +hospitalizations. + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Acute kidney failure, unspecified; Intestinal infection due to Clostridium difficile; Urinary tract infection, site not specified; Other ascites; Congestive heart failure, unspecified; Other specified forms of chronic ischemic heart disease; Coronary atherosclerosis of native coronary artery; Other chronic pulmonary heart diseases; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Unspecified acquired hypothyroidism; Friedl?nder's bacillus infection in conditions classified elsewhere and of unspecified site; Pressure ulcer, buttock; Pressure ulcer, stage II; Peripheral vascular disease, unspecified; Personal history of venous thrombosis and embolism; Automatic implantable cardiac defibrillator in situ]" +11638,155878.0,15383,2180-01-21,15382,122879.0,2179-12-03,Discharge summary,"Admission Date: [**2179-11-21**] Discharge Date: [**2179-12-3**] + +Date of Birth: [**2108-5-29**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**Last Name (NamePattern1) 1167**] +Chief Complaint: +shoulder pain + +Major Surgical or Invasive Procedure: +1. Irrigation and debridement left shoulder via anterolateral +deltopectoral miniarthrotomy with cultures. +2. Aspiration left hip joint under fluoroscopy. +3. Irrigation and debridement 3rd metacarpophalangeal joint, +superficial abscess. +4. Endotracheal Intubation + +History of Present Illness: +71 yo F w/ CAD, ischemic CMY (EF 10%) s/p [**Hospital1 **]-V ICD, atrial +fibrillation, CKD, with past history of DVT and PE on Coumadin +who was recently discharged from the CCU ([**11-6**]) for CHF +exacerbation c/b C.diff infection, who is now being transferred +from [**Hospital **] hospital for ?Septic shoulder joint and hypoxia, +requiring intubation. Patient is intubated and sedated so +history obtained from HCP (niece) and transfer records. She +presented to [**Location (un) **] on [**11-18**] with left shoulder pain. +Orthopedics was consulted and joint aspiration was done which +showed +hemarthrosis. Joint culture now growing staph aureus. +She was given oxacillin initially and then per discharge note, +received Vancomycin althouth transfer medication list does not +have Vancomycin listed as being given. Today, the patient +developed hypoxia and required increasing O2 requirement and was +placed on a NRB with O2 sat in 90-92% range per HCP. O2 sat +then declined to 70% on NRB and patient was then electively +intubated prior to transfer. + + +Past Medical History: +1. CARDIAC RISK FACTORS: Dyslipidemia, Hypertension +2. CARDIAC HISTORY: +-CABG: None +-PERCUTANEOUS CORONARY INTERVENTIONS: BM stent to the LAD in +[**2164**], Occluded RCA/no intervention +-PACING/ICD: Ischemic cardiomyopathy (EF 10-25%) s/p BiV ICD and +atrial fibrillation +3. H/o PE secondary to DVT s/p IVC filter on Coumadin +4. PVD +5. Small VSD +6. Hypothyroidism +7. CKD +8. Osteoarthritis + + +Social History: +-Tobacco history: 20 pack year history, however she quit 30 yrs +ago +-ETOH: Denies +-Illicit drugs: Denies +Pt lives alone but currently resides at [**Hospital 599**] rehab. She is not +married. + + +Family History: +Mother had MI at age 50, maternal uncle died of MI in his 50's. + +No family history of arrhythmia, cardiomyopathies, or sudden +cardiac death; otherwise non-contributory. + +Physical Exam: +VS: Temp BP 99/58 HR 70 RR 14 on AC TV 450, PEEP 5, 100% +FiO2 +GENERAL: Elderly female, intuabed, sedated +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. +NECK: Supple with JVP to angle of jaw +CARDIAC: normal S1, S2. II/VI SEM, RRR +LUNGS: CTAB, no wheezes, crackles or ronchi +ABDOMEN: Soft, NT, +ascites, +fluid wave +EXTREMITIES: No c/c/e, dopplerable pedal pulses, Right shoulder +with +effusion no erythema, right MCP joint with +blanching +erythema and edema, +TTP +SKIN: +dry skin + +Pertinent Results: +ADMISSION LABS [**2179-11-21**]: +[**2179-11-21**] 03:48AM WBC-10.9# Hgb-12.3 Hct-39.3 Plt Ct-207 +[**2179-11-21**] 03:48AM PT-80.1* PTT-48.4* INR(PT)-9.6* +[**2179-11-21**] 03:48AM Glucose-141* UreaN-70* Creat-2.7* Na-129* +K-5.5* Cl-93* HCO3-22 AnGap-20 +[**2179-11-21**] 03:48AM ALT-9 AST-17 LD(LDH)-213 CK(CPK)-15* +AlkPhos-130* TotBili-1.7* +[**2179-11-21**] 03:48AM CK-MB-NotDone cTropnT-0.07* +[**2179-11-21**] 03:48AM Albumin-3.5 Calcium-8.9 Phos-4.6*# Mg-2.4 +[**2179-11-21**] 03:48AM ESR-30* +[**2179-11-21**] 03:48AM CRP-291.3* +[**2179-11-21**] 03:48AM Vanco-10.1 +[**2179-11-21**] 03:48AM Digoxin-3.8* +[**2179-11-21**] 04:13AM Type-ART pO2-81* pCO2-46* pH-7.32* calTCO2-25 +Base XS--2 +[**2179-11-21**] 04:13AM Lactate-1.4 + +URINE: +[**2179-11-21**] 05:45AM Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.007 +[**2179-11-21**] 05:45AM Blood-NEG Nitrite-NEG Protein-NEG Glucose-NEG +Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-TR +[**2179-11-21**] 05:45AM RBC-[**2-18**]* WBC-[**5-26**]* Bacteri-RARE Yeast-NONE +Epi-0-2 RenalEp-[**2-18**] +[**2179-11-21**] 05:45AM Hours-RANDOM UreaN-190 Creat-20 Na-69 + +JOINT FLUID: +[**2179-11-21**] 10:19AM WBC-[**Numeric Identifier **]* RBC-[**Numeric Identifier 44665**]* Polys-84* Lymphs-3 +Monos-5 Macro-8 +[**2179-11-21**] 10:19AM Crystal-FEW Shape-RHOMBOID Locatio-INTRAC +Birefri-POS Comment-c/w calcium phosphate deposits +[**2179-11-25**] 08:30AM WBC-[**Numeric Identifier 42138**]* RBC-[**Numeric Identifier 44666**]* Polys-91* Lymphs-1 +Monos-8 + +OTHER PERTINENT LABS: +[**2179-11-21**] 03:48AM INR(PT)-9.6* +[**2179-11-21**] 10:24AM INR(PT)-11.2* +[**2179-11-21**] 08:04PM INR(PT)-3.3* +[**2179-11-22**] 04:04AM INR(PT)-3.4* +[**2179-11-23**] 02:30AM INR(PT)-2.7* +[**2179-11-24**] 06:29AM INR(PT)-2.8* +[**2179-11-24**] 03:32PM INR(PT)-2.8* +[**2179-11-25**] 03:28AM INR(PT)-2.7* +[**2179-11-25**] 11:27AM INR(PT)-2.0* +[**2179-11-26**] 05:25AM INR(PT)-2.4* +[**2179-11-27**] 03:10AM INR(PT)-2.5* +[**2179-11-28**] 03:56AM INR(PT)-2.2* +[**2179-11-29**] 02:56AM INR(PT)-2.0* +[**2179-11-29**] 10:56AM INR(PT)-2.0* +[**2179-11-30**] 05:44AM INR(PT)-1.8* + +MICRO: +[**Date range (1) 44667**] BCx: MRSA +[**2179-11-21**] MRSA Screen: positive +[**2179-11-21**] Joint fluid (shoulder): MRSA +[**2179-11-21**] UCx: negative +[**2179-11-21**] Sputum Cx: respiratory flora +[**2179-11-23**] Catheter tip: negative +[**2179-11-25**] Joint fluid (L hip): MRSA +[**2179-11-25**] R 3rd MCP: MRSA +[**2179-11-25**] Shoulder: MRSA +[**Date range (1) 44668**] BCx: NGTD + +IMAGING: +[**2179-11-21**] CXR: +There is opacification in the right upper zone. This could +represent volume loss in the right upper lobe or possible +supervening consolidation. + +[**2179-11-21**] Repeat CXR: +In comparison with the earlier study of this date, there has +been +substantial clearing of the right upper lung opacification. This +suggests +expectoration of a mucous plug with relief of volume loss. + +[**2179-11-21**] Shoulder XR: +No previous films are available for comparison. There is +sclerosis, with narrowing and some irregularity involving the +glenohumeral +joint. This may merely reflect degenerative changes, though the +possibility of an indolent infection cannot be excluded. MRI +might be helpful for further evaluation. + +[**2179-11-21**] Hand XR: +The third MCP joint is quite well maintained without convincing +erosions. Degenerative change is seen involving the first CMC as +well as the second DIP joint. Some narrowing is also seen +involving several other DIP and PIP joints. + +[**2179-11-22**] CXR: +No significant change from prior exam, allowing for significant +leftward rotation of the patient + +[**2179-11-23**] ECHO: +The left atrial appendage emptying velocity is depressed +(<0.2m/s). A probable thrombus is seen in the left atrial +appendage. No mass or thrombus is seen in the right atrium or +right atrial appendage. No atrial septal defect is seen by 2D or +color Doppler. Overall left ventricular systolic function is +severely depressed. The right ventricular cavity is dilated with +moderate global free wall hypokinesis. There are simple atheroma +in the ascending aorta. There are simple atheroma in the aortic +arch. There are simple atheroma in the descending thoracic +aorta. The aortic valve leaflets (3) are mildly thickened but +aortic stenosis is not present. No masses or vegetations are +seen on the aortic valve. No aortic regurgitation is seen. The +mitral valve leaflets are structurally normal, though restricted +motion of the posterior leaflet is seen. There is no mitral +valve prolapse. No mass or vegetation is seen on the mitral +valve. Mild (1+) mitral regurgitation is seen. Moderate [2+] +tricuspid regurgitation is seen. [Due to acoustic shadowing, the +severity of tricuspid regurgitation may be significantly +UNDERestimated.] No vegetation/mass is seen on the pulmonic +valve. There is a trivial/physiologic pericardial effusion. + +IMPRESSION: No valvular vegetation or wire-associated +vegetation. Probable left atrial appendage thrombus with +spontaneous echo contrast also identified within the body of the +left atrial appendage. Mild mitral regurgitation, at least +moderate tricuspid regurgitation. Severe biventricular systolic +dysfunction. + +[**2179-11-29**] ECHO: +The left atrium is elongated. The right atrium is markedly +dilated. The interatrial septum is aneurysmal. The estimated +right atrial pressure is 10-20mmHg. Left ventricular wall +thicknesses are normal. The left ventricular cavity is +moderately dilated with severe global hypokinesis. The basal +inferolateral wall contracts best (LVEF = 20 %). The estimated +cardiac index is borderline low (2.0-2.5L/min/m2). No masses or +thrombi are seen in the left ventricle. The right ventricular +cavity is moderately dilated with severe global free wall +hypokinesis. [Intrinsic right ventricular systolic function is +likely more depressed given the severity of tricuspid +regurgitation.] The ascending aorta is mildly dilated. The +aortic valve leaflets (3) are mildly thickened but aortic +stenosis is not present. Trace aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Mild to moderate ([**12-18**]+) mitral regurgitation is +seen. Moderate to severe [3+] tricuspid regurgitation is seen. +There is moderate pulmonary artery systolic hypertension. +Significant pulmonic regurgitation is seen. There is a very +small circumferential pericardial effusion without +echocardiographic signs of tamponade. + +Compared with the prior study (images reviewed) of [**2179-10-26**], +estimated pulmonary artery systolic pressure is now higher + +DISCHARGE LABS: + +Brief Hospital Course: +71 yo F w/ CAD, ischemic CMY (EF 10%) s/p [**Hospital1 **]-V ICD, atrial +fibrillation, CKD, with past history of DVT and PE on Coumadin +who was recently discharged from the CCU ([**11-6**]) for CHF +exacerbation complicated by C.diff infection who was transferred +from an outside hospital with a septic shoulder joint and acute +respiratory failure requiring intubation. + +1. Respiratory Failure: Patient has history of CHF with EF 10% +which is the likely cause of her respiratory failure. She was +diuresed agressivly with lasix drip, weaned from vent. She was +also maintained on dopamine to maintain high cardiac output, +eventually weaned off and restarted on digoxin. Her respiratory +status continued to improve with diuresis. At time of discharge +she was saturating well on room air. +Of note, the patient changed her code status to DNR/DNI +following extubation although she briefly reversed this status +to be taken to the operating room (see below). However, on day +of discharge, she reversed herself and decided she did want CPR, +intubation and pressors for short term therapy only. She stated +she would not want to be intubated long term. + +2. Septic Joint: Patient with + staph aureus in left shoulder +and later, blood cultures from the outside hospital also grew +MRSA. Presented with low BP, requiring pressor support likely a +combination of sepsis and cardiogenic shock (see below). Per +report, patient also had +hemearthrosis of left shoulder in the +setting of supratherapeutic INR. Patient's picc line was felt +to be the likely source of infection and this line was +discontinued at the time of admission. Initially, it was +unclear if Staph aureus in culture at OSH was a contaminant, +given that physical exam was not entirely consistent with a +spetic joint. Vancomycin was continued and ortho reaspirated +the left shoulder on day of admission; fluid analysis confirmed +bacterial infection. On [**11-25**], the patient was taken to the +operating room for washout of shoulder and right 3rd MCP joint, +both of which contained pus. Left hip was also aspirated, which +eventually grew MRSA also. Patient was continued on Vancomycin +with routine trough levels monitored. Blood cultures were +followed daily and remained positive until [**2179-11-25**]. Echo on +[**11-23**] showed no evidence of endocarditis although an intraatrial +thrombus was visualized which may be infected. The patient will +need prolonged therapy with vancomycin. She will follow up with +in the infectious disease clinic. + +3. CORONARIES: Patient with history of extensive CAD with right +dominant system, mild instent re-stenois of the LAD BM stent and +occluded RCA. Throughout hospitalization, patient had no +subjective or objective symptoms of ischemia, and serial cardiac +enzymes were stable. Initially, b-blocker was held secondary to +severe hypotension requiring pressor support although aspirin +continued. By time of discharge, patient was also tolerating +low dose b-blocker and ACEI. + +4. PUMP: Patient with history of ischemic cardiomyopathy, EF +10%, s/p BiV ICD ([**Company 1543**] Concerto C154DWK) on [**12-24**]. +Presented with symptoms of acute on chronic congestive heart +failure with symptoms of both volume overload (high RV pressure, +pulmonary edema, ascites, peripheral edema) and poor cardiac +output (acute on chronic kidney failure, hypotension). With +initial hypotension, a CVL was inserted with attempt to float a +swan-ganz catheter to better assess fluid status. +Unfortunately, due to technical difficulties, PA catheter was +not able to be placed and the patient was treated with dopamine +to improve cardiac output. Once blood pressure had stabilized +and systemic infection improved, patient was started on lasix +drip for aggressive diuresis. Prior to discharge, patient was +restarted on her home medication regimen of torsemide, +lisinopril and metoprolol. Of note, patient was also restarted +on digoxin after discontinuation of dopamine. These levels will +need to be monitored carefully given patient's fluctuating +creatinine clearance. + +5. RHYTHM: Patient with h/o atrial fibrillation, s/p BiV ICD +([**Company 1543**] Concerto C154DWK) [**12-24**], on coumadin and amiodarone as +antiarrhythmic. Presented with supratherapeutic INR and +hemarthosis of left shoulder. Coagulopathy was reversed with +FFP prior to shoulder and MCP washout. Found to have +intra-atrial thrombus on TEE during hospitalization. Needs to +be maintained on heparin gtt following surgical procedure until +coumadin reached theraputic goal of INR [**1-19**]. Heparin can be held +while vancomycin is infusing. + +6. Acute on CRF: Patient w/ baseline Cr 1.3-1.8, 2.4 on +presentation, likely related to poor forward flow from CHF. +Medications were renal dosed and renal function followed +carefully throughout hospital course. Kidney function improved +to baseline by time of discharge. + +7. H/o DVT/PE: Patient has h/o DVT/PE currently on coumadin and +has [**Initials (NamePattern4) **] [**Last Name (NamePattern4) 260**] filter in place. As noted above, patient +presented with supratherapeutic INR which was reversed prior to +surgical intervention. For the duration of the hospital stay, +the patient was maintained on heparin gtt, which should be +continued until coumadin reachs therapeutic levels again, +2.0-3.0. + +8. Hypothyroidism: stable, continue Levothyroxine. + +9. Access: The patient had a new single lumen PICC line placed +in her right arm on [**2179-11-30**] by interventional radiology. The +PICC line would not pass beyond the mid-clavicular area due to a +stenosis in the subclavian vein. It was cut to this length and +is slightly longer than a traditional midline. A PICC cannot be +placed in the other arm because of her pacemaker. The patient +should get her vancomycin infusion over an hour. Her vancomycin +should be diluted into 250ml to decrease the chance of fibrosis +or irration to this artery. Please monitor the patient's arm +for swelling or pain because she is at an increased risk of +clot, however, she is on anticoagulation. + +10. CODE STATUS: Full code on [**2179-12-3**] + +Medications on Admission: +Allopurinol 100mg daily +Amiodarone 200mg daily +Aspirin 81mg daily +Vit C 500mg daily +Cholestyramine 4gm [**Hospital1 **] +Digoxin 0.0625mg daily +Levothyroxine 0.125mg daily +Metolazone 2.5mg daily +Metoprolol Tartrate 12.5mg [**Hospital1 **] +MVI +Omeprazole 20mg daily +Simvastatin 20mg qHS +Torsemide 40mg daily +Zinc Sulfate 220mg daily +Warfarin +Oxacillin 1gm q6h +Propofol bolus for intubation, changed to Fentanyl/Versed +Dilaudid 0.4mg q4h PRN pain +Vicodin 1-2 tabs q4h PRN pain + +Discharge Medications: +1. Outpatient Lab Work +Please get weekly CBC with differential, BUN/ Creatinine and +vancomycin trough. Start date: [**2179-12-8**] +Fax results to [**Hospital **] clinic: [**Telephone/Fax (1) 1419**] +2. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +3. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Allopurinol 100 mg Tablet Sig: One (1) Tablet PO EVERY OTHER +DAY (Every Other Day). +5. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +7. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +8. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day) as needed for constipation. +9. Acetaminophen 500 mg Tablet Sig: Two (2) Tablet PO Q 8H +(Every 8 Hours): Please d/c once pain well controlled. +10. Tramadol 50 mg Tablet Sig: One (1) Tablet PO QID (4 times a +day). +11. Metoprolol Succinate 25 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO DAILY (Daily). +12. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily): +HOLD SBP < 85. +13. Warfarin 2 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM. +14. Simvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +15. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO Q4H (every 4 +hours) as needed for pain. +16. Torsemide 20 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +17. Digoxin 125 mcg Tablet Sig: 0.5 Tablet PO EVERY OTHER DAY +(Every Other Day). +18. Vancomycin 500 mg IV Q 24H +19. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. +20. Heparin (Porcine)-0.45% NaCl 25,000 unit/250 mL Parenteral +Solution Sig: sliding scale units Intravenous continuous. +21. Heparin Lock 10 unit/mL Solution Sig: Two (2) ml Intravenous +after NS flush. +22. Saline Flush 0.9 % Syringe Sig: Ten (10) cc Injection before +and after vancomycin dose. +23. Outpatient Lab Work +Please get chem-7 every 3 days to follow K, Na and renal status. + + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital1 700**] - [**Location (un) 701**] + +Discharge Diagnosis: +Primary Diagnosis: +Septic Joint +acute on chronic congestive heart failure +intra-atrial thrombus + +Secondary Diagnosis: +atrial fibrillation + + +Discharge Condition: +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Out of Bed with assistance to chair or +wheelchair + + +Discharge Instructions: +You were admitted to the hospital with left shoulder pain. You +were found to have an infection in your shoulder that had spread +to your blood, left hip and right hand. In the operating room, +the orthopedic doctors [**Name5 (PTitle) 44669**] out your infected joints which +should help cure your infection. You were also started on +vancomycin, an antibiotic that you will need to continue after +you leave the hospital. You should follow up with the +infectious disease specialists who will determine how long you +need to continue the vancomycin. +. +You also had difficulty breathing when you first came to the +hospital, requiring a breathing tube. Your trouble breathing +was likely caused by an exacerbation of your heart failure which +caused fluid to accumulate on your lungs. We treated you with +medications to help remove this excess fluid and the breathing +tube was able to be removed. +Medication changes: +1. Start Vancomycin to treat the joint and blood infections. +2. Decrease the Torsemide to 20 mg twice daily +3. Decrease the Digoxin to every other day +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight goes up more +than 3 lbs in 1 day or 6 pounds in 3 days. + +Followup Instructions: +Please follow up in infectious disease clinic with Dr. [**First Name (STitle) **] +on [**2179-12-24**] at 9:30. Phone:[**Telephone/Fax (1) 457**] [**Hospital Unit Name **] +[**Location (un) 448**], [**Doctor First Name **], [**Location (un) 86**]. +. +Cardiology: +Dr. [**First Name8 (NamePattern2) 401**] [**Last Name (NamePattern1) 437**] Phone [**Telephone/Fax (1) 62**] Date/Time: Monday [**12-13**] at +9:00am. [**Hospital Ward Name 23**] clinical center, [**Location (un) 436**], [**Hospital Ward Name 516**] [**Hospital1 18**]. +. +Ortho: +[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] NP. Date/Time: [**12-21**] at 11:00am. [**Hospital Ward Name 23**] +Clinical Center, [**Location (un) **], [**Location (un) **], [**Hospital Ward Name 516**], +[**Hospital1 18**]. + + + +",49,2179-11-21 01:05:00,2179-12-03 16:20:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,BIVENTRICULAR HEART FAILURE," +71 yo f w/ cad, ischemic cmy (ef 10%) s/p [**hospital1 **]-v icd, atrial +fibrillation, ckd, with past history of dvt and pe on coumadin +who was recently discharged from the ccu ([**11-6**]) for chf +exacerbation complicated by c.diff infection who was transferred +from an outside hospital with a septic shoulder joint and acute +respiratory failure requiring intubation. + +1. respiratory failure: patient has history of chf with ef 10% +which is the likely cause of her respiratory failure. she was +diuresed agressivly with lasix drip, weaned from vent. she was +also maintained on dopamine to maintain high cardiac output, +eventually weaned off and restarted on digoxin. her respiratory +status continued to improve with diuresis. at time of discharge +she was saturating well on room air. +of note, the patient changed her code status to dnr/dni +following extubation although she briefly reversed this status +to be taken to the operating room (see below). however, on day +of discharge, she reversed herself and decided she did want cpr, +intubation and pressors for short term therapy only. she stated +she would not want to be intubated long term. + +2. septic joint: patient with + staph aureus in left shoulder +and later, blood cultures from the outside hospital also grew +mrsa. presented with low bp, requiring pressor support likely a +combination of sepsis and cardiogenic shock (see below). per +report, patient also had +hemearthrosis of left shoulder in the +setting of supratherapeutic inr. patients picc line was felt +to be the likely source of infection and this line was +discontinued at the time of admission. initially, it was +unclear if staph aureus in culture at osh was a contaminant, +given that physical exam was not entirely consistent with a +spetic joint. vancomycin was continued and ortho reaspirated +the left shoulder on day of admission; fluid analysis confirmed +bacterial infection. on [**11-25**], the patient was taken to the +operating room for washout of shoulder and right 3rd mcp joint, +both of which contained pus. left hip was also aspirated, which +eventually grew mrsa also. patient was continued on vancomycin +with routine trough levels monitored. blood cultures were +followed daily and remained positive until [**2179-11-25**]. echo on +[**11-23**] showed no evidence of endocarditis although an intraatrial +thrombus was visualized which may be infected. the patient will +need prolonged therapy with vancomycin. she will follow up with +in the infectious disease clinic. + +3. coronaries: patient with history of extensive cad with right +dominant system, mild instent re-stenois of the lad bm stent and +occluded rca. throughout hospitalization, patient had no +subjective or objective symptoms of ischemia, and serial cardiac +enzymes were stable. initially, b-blocker was held secondary to +severe hypotension requiring pressor support although aspirin +continued. by time of discharge, patient was also tolerating +low dose b-blocker and acei. + +4. pump: patient with history of ischemic cardiomyopathy, ef +10%, s/p biv icd ([**company 1543**] concerto c154dwk) on [**12-24**]. +presented with symptoms of acute on chronic congestive heart +failure with symptoms of both volume overload (high rv pressure, +pulmonary edema, ascites, peripheral edema) and poor cardiac +output (acute on chronic kidney failure, hypotension). with +initial hypotension, a cvl was inserted with attempt to float a +swan-ganz catheter to better assess fluid status. +unfortunately, due to technical difficulties, pa catheter was +not able to be placed and the patient was treated with dopamine +to improve cardiac output. once blood pressure had stabilized +and systemic infection improved, patient was started on lasix +drip for aggressive diuresis. prior to discharge, patient was +restarted on her home medication regimen of torsemide, +lisinopril and metoprolol. of note, patient was also restarted +on digoxin after discontinuation of dopamine. these levels will +need to be monitored carefully given patients fluctuating +creatinine clearance. + +5. rhythm: patient with h/o atrial fibrillation, s/p biv icd +([**company 1543**] concerto c154dwk) [**12-24**], on coumadin and amiodarone as +antiarrhythmic. presented with supratherapeutic inr and +hemarthosis of left shoulder. coagulopathy was reversed with +ffp prior to shoulder and mcp washout. found to have +intra-atrial thrombus on tee during hospitalization. needs to +be maintained on heparin gtt following surgical procedure until +coumadin reached theraputic goal of inr [**1-19**]. heparin can be held +while vancomycin is infusing. + +6. acute on crf: patient w/ baseline cr 1.3-1.8, 2.4 on +presentation, likely related to poor forward flow from chf. +medications were renal dosed and renal function followed +carefully throughout hospital course. kidney function improved +to baseline by time of discharge. + +7. h/o dvt/pe: patient has h/o dvt/pe currently on coumadin and +has [**initials (namepattern4) **] [**last name (namepattern4) 260**] filter in place. as noted above, patient +presented with supratherapeutic inr which was reversed prior to +surgical intervention. for the duration of the hospital stay, +the patient was maintained on heparin gtt, which should be +continued until coumadin reachs therapeutic levels again, +2.0-3.0. + +8. hypothyroidism: stable, continue levothyroxine. + +9. access: the patient had a new single lumen picc line placed +in her right arm on [**2179-11-30**] by interventional radiology. the +picc line would not pass beyond the mid-clavicular area due to a +stenosis in the subclavian vein. it was cut to this length and +is slightly longer than a traditional midline. a picc cannot be +placed in the other arm because of her pacemaker. the patient +should get her vancomycin infusion over an hour. her vancomycin +should be diluted into 250ml to decrease the chance of fibrosis +or irration to this artery. please monitor the patients arm +for swelling or pain because she is at an increased risk of +clot, however, she is on anticoagulation. + +10. code status: full code on [**2179-12-3**] + + ","PRIMARY: [Methicillin resistant Staphylococcus aureus septicemia] +SECONDARY: [Acute respiratory failure; Acute kidney failure, unspecified; Septic shock; Acute on chronic systolic heart failure; Pyogenic arthritis, shoulder region; Hemarthrosis, shoulder region; Ventricular septal defect; Severe sepsis; Atrial fibrillation; Other ill-defined heart diseases; Other specified forms of chronic ischemic heart disease; Chronic kidney disease, unspecified; Coronary atherosclerosis of native coronary artery; Chronic total occlusion of coronary artery; Unspecified acquired hypothyroidism; Congestive heart failure, unspecified; Percutaneous transluminal coronary angioplasty status; Automatic implantable cardiac defibrillator in situ; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism]" +11638,122879.0,15382,2179-12-03,15381,136238.0,2179-11-06,Discharge summary,"Admission Date: [**2179-10-26**] Discharge Date: [**2179-11-6**] + +Date of Birth: [**2108-5-29**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**Last Name (NamePattern1) 1167**] +Chief Complaint: +Increasing Dyspnea + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with LVEF of 10%, atrial fibrillation, [**Hospital1 **]-V ICD, CKD, with past +history of DVT, PE on Coumadin who presents with increasing +dyspnea. The patient was recently discharged from [**Hospital1 18**] CCU on +[**9-22**] for CHF exacerbation and was discharged to rehab facility. +Since that time, patient was hospitalized at [**Location (un) **] two weeks +ago for pneumonia. + +The patient reports that over the past week, the patient has had +increasing dyspnea with exertion. At baseline, patient is unable +to perform ADLs without the assistance of physical therapy. Over +the past week, there has been a noticible worsening in her +physical limitations. The patient recently saw Dr. [**First Name (STitle) 437**] as an +outpatient and had her dose of Torsemide increased from 20mg to +40mg and Carvedilol was discontinued and switched to Metoprolol +tartrate 12.5mg [**Hospital1 **]. + +Patient was taken to [**Hospital **] hospital for initial evaluation and +was given another dose of torsemide 40mg x 1 and then +transferred to [**Hospital1 18**] as her cardiac care is here. Patient's +initial VS in the ED were 98.3 76 105/70 16 96 on 4LNC. Pt was +initially dyspneic, RR in 20s, wheezes bilaterally. Ascities +worse than in past few weeks. 2+ pedal edema. + +Cardiac review of systems is notable for presence of chest pain +at rehab, dyspnea on exertion, paroxysmal nocturnal dyspnea, +orthopnea, ankle edema. No palpitations, syncope or presyncope. + + +Past Medical History: +. ischemic cardiomyopathy (EF 10-25%) s/p BiV ICD +2. Coronary artery disease status post PTCA and stenting of the + +LAD in [**2164**]. +3. h/o PE secondary to DVT s/p IVC filter +4. Atrial fibrillation status post cardioversion and +biventricular pacemaker implantation. +5. HTN +6. Obesity +7. PVD +8. small VSD +9. hypothyroidism +PAST MEDICAL HISTORY: +1. CARDIAC RISK FACTORS: + Dyslipidemia +2. CARDIAC HISTORY: +-Ischemic cardiomyopathy EF %15-20 s/p biv ICD +-CAD s/p post PTCA and stenting of the LAD in [**2164**]. +-CABG: None +-PACING/ICD: atrial fibrillation on anticoagulation and ICD +biventricular pacemaker +3. OTHER PAST MEDICAL HISTORY: +chronic kidney disease +bilateral DVT s/[**Initials (NamePattern4) **] [**Last Name (NamePattern4) **] filter +pulmonary embolism +osteoarthritis +hyperkalemia + + +Social History: +Pt lives alone but currently resides at [**Hospital 599**] rehab. She is not +married. She reports a 20 pack year history, however she quit 30 +yrs ago. Denies EtOH or illicit drug use. + + +Family History: +Mother had MI at age 50. Father in good health. Maternal uncle +died of MI in his 50's. + +Physical Exam: +VS: 99.5, 95/60, 80, 22, 94% 3L NC +GENERAL: NAD. Oriented x3. Mood, affect appropriate. +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. No xanthalesma. + +NECK: Supple with JVP of 15 cm. +CARDIAC: PMI inferolaterally displaced, RR, normal S1, S2. +Holosystolic murmur at apex. +LUNGS: Bilateral rales to mid-lung fields. +ABDOMEN: Soft, distended. + Fluid wave. Mild Hepatomegaly. +Unable to palpate spleen. +EXTREMITIES: +2 BLE edema. RLE > LLE. Warm +SKIN: No stasis dermatitis, ulcers, scars, or xanthomas. +PULSES: +Right: DP 1+ PT 1+ +Left: DP 1+ PT 1+ + +Pertinent Results: +Admission Labs: +[**2179-10-26**] 12:30AM WBC-6.2# RBC-3.60* HGB-11.3* HCT-34.7* MCV-96 +MCH-31.3 MCHC-32.5 RDW-18.6* +[**2179-10-26**] 12:30AM PLT SMR-NORMAL PLT COUNT-182# +[**2179-10-26**] 12:30AM PT-28.4* PTT-36.3* INR(PT)-2.8* +[**2179-10-26**] 12:30AM CK-MB-NotDone proBNP-[**Numeric Identifier 44663**]* +[**2179-10-26**] 12:30AM cTropnT-0.04* +[**2179-10-26**] 12:30AM ALT(SGPT)-51* AST(SGOT)-56* CK(CPK)-62 ALK +PHOS-194* TOT BILI-1.7* +[**2179-10-26**] 12:30AM GLUCOSE-112* UREA N-48* CREAT-1.6* SODIUM-136 +POTASSIUM-4.6 CHLORIDE-97 TOTAL CO2-27 ANION GAP-17 +. +EKG: [**2179-10-26**] 0003: V Paced at 69, w/ RAD, bifascicular block. +. +TTE [**10-26**]: +The left atrium is moderately dilated. The right atrium is +markedly dilated. There is mild symmetric left ventricular +hypertrophy. The left ventricular cavity is moderately dilated. +There is severe regional left ventricular systolic dysfunction +with anterior, septal and apical akinesis, as well as akinesis +of the distal inferior wall (proximal LAD distribution). There +is mild hypokinesis of the remaining segments (LVEF = 15-20%). +No masses or thrombi are seen in the left ventricle. The right +ventricular cavity is moderately dilated with severe global free +wall hypokinesis. The aortic valve leaflets (3) are mildly +thickened but aortic stenosis is not present. Mild to moderate +([**12-18**]+) mitral regurgitation is seen. Severe [4+] tricuspid +regurgitation is seen. There is mild pulmonary artery systolic +hypertension. There is a trivial/physiologic pericardial +effusion. +. +IMPRESSION: Dilated left ventricle with severe regional systolic +dysfunction, c/w an extensive prior LAD infarction. Dilated +right ventricle with severe systolic dysfunction. Mild to +moderate mitral regurgitation. Severe tricuspid regurgitation. +At least mild pulmonary hypertension. +. +Compared with the prior study (images reviewed) of [**2177-5-26**], +severity of tricuspid regurgitation has increased. The other +findings are similar. +. +RLE US [**10-26**]: No right lower extremity DVT. +ABD DOPPLER [**10-26**]: +1. Distended hepatic veins and ascites, the constellation of +findings can be seen in the setting of congestive heart failure. +Otherwise, normal Doppler examination of the liver. +. +2. No evidence of biliary pathology. +. +MYOCARDIAL VIABILITY STUDY [**10-27**]: +Within limitation of current study, fixed defects in distal +anterior +and apical walls are consistent with scarring. Improvement of +inferior wall defect with correction is suggestive of myocardial +viability. +. +LHC/RHC [**11-2**]: +COMMENTS: +1. Selective coronary angiography of this right dominant system +revealed +one vessel coronary artery disease. The LMCA had no +angiographically +apparent disease. The LAD had mild instent restenosis of the +prior +stent. The LCx had no angiographically apparent disease. The RCA +was +occluded and similar to prior. +2. Resting hemodynamics on milrinone therapy revealed moderately + +elevated right and left sided filling pressures with an RVEDP of +15 mmHg +and PCWP of 20 mmHg. There was moderate pulmonary hypertension +with a +PASP of 42/20 mmHg. There was normal systemic blood pressure +with +central pressure of 108/63 mmHg. There was a low-normal cardiac +index of +2.1 L/min/m2. There was no transaortic valve gradient on careful + +pullback from LV to aorta. +3. Peripheral angiography revealed patent renal arteries +bilaterally. +. +FINAL DIAGNOSIS: +1. One vessel coronary artery disease. +2. Moderate biventricular diastolic dysfunction. +3. Moderate pulmonary hypertension. +4. Normal systemic pressure. +5. Low-normal cardiac index. +6. Patent renal arteries. +. +KUB [**11-2**]: +1. There is no ileus or small bowel obstruction. +2. Tubular radiopaque left paraspinal structure of unknown +etiology warrants repeat AP and lateral radiograph. +. + + +Brief Hospital Course: +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with LVEF of 10%-15%, atrial fibrillation, [**Hospital1 **]-V ICD, low cardiac +output state, chronic kidney disease with past history of DVT, +PE on Coumadin. + +#. NYHA Class 4 Systolic congestive Heart Failure, EF 15%. with +severe volume overloaded on examination on admission. She had a +low output state with known low EF and dilated ischemic +cardiomyopathy. It was felt that she would likely need +inotropic support and she was sent to the CCU for diuresis with +milrinone gtt + lasix gtt + metolazone. The patient had +significant diuresis on this regimen. It was felt that if there +was viable myocardium currently hibernating [**1-18**] low perfusion +state, intervention may improve cardiac function. A myocardial +viability study was performed and demonstrated inferior wall +myocardial viability. LHC/RHC were performed but no +intervenable targets were appreciated; additionally, the patient +was thought to be a poor candidate for CABG/TR [**1-18**] poor targets +for grafts. It was therefore felt that the patient could only +be maximized on medical therapy. Diuresis was changed to PO on +[**11-5**] to her precious dose of Torsemide and metolazone was added +daily to regimen. Weight on discharge________. Would follow +lytes every other day until stable and weekly thereafter. + +# C-diff colitis - Positive C. difficile toxin assay. Patient +was started on PO metronidazole and cholesyramine with clinical +improvement as gauged by frequency of diarrhea, fever, and WBC +count. Peak WBC 11.4. Flagyl to be continued x 7 more days. +Once 2 week flagyl course is finished, can consider restarting +immodium for symptomatic relief. + +# UTI - Patient was found to have UTI [**1-18**] Klebsiella pneumoniae, +pansensitive except for intermediate sensitivity to +nitrofurantoin. She was started on ciprofloxacin for 7 day +course, finished on [**11-4**]. + +#. Rhythm: She has a BiV ICD in place and was V-paced on ECG. +She was monitored on telemetry. No events. + +#. Coronaries: Patient with mid-LAD BMS '[**64**]. Trop 0.04, CK-MB +negative that was likely related to CHF exacerbation. She was +continued on a statin and aspirin. + +#. URI: She had been diagnosed with a URI prior to admission and +had been started on Zithromax. This was held in the hospital +and sputum cultures were sent, found to be negative. Pt is +currently asymptomatic. + +#. Asicites: She had significant ascities on exam and she was +s/p 6L tap two weeks ago. It was felt her ascites was likely +related to right-sided heart failure and would be difficult to +resolve with diuretics. She was restarted on her home regimen of +torsemide plus Metolazone as noted above. + +#. LFT abnormalities: She had a mild transaminities with an AP +190, TBili 1.7. It appeared to be obstructive pattern, likely +related to congestive hepatopathy. Resolved prior to discharge. + +#. H/o DVT/PE: She was anticoagulated with Coumadin and has a +[**Location (un) 260**] filter in place. She had a RLE U/S that showed no +DVT. Her INR today is _______. INR should be followed every +other day until stable and weekly thereafter. + +# Hypothyroidism: Continued Levothyroxine. + +# CODE: She was full code during this hospitalization. It is +thought that she is end stage in regard to her CHF with medical +treatment her only option at this time. Palliative care was not +persued during this hospital stay but may be introduced by Dr. +[**First Name (STitle) 437**]/[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] [**MD Number(3) 44664**] continues to have frequent +hospitalizations. + +Medications on Admission: +Allopurinol 100mg daily +Amiodarone 200mg daily +Levothyroxine 125mcg daily +ASA 81mg daily +Zocor 20mg daily +Zithromax 250mg daily (until [**10-26**]) for URI +Torsemide 40mg po BID +Metoprolol Succinate 12.5mg po BID +Digoxin 0.0625 mcg daily +Prilosec 20mg daily +Zinc 220mg po daily +Vit C 500mg po daily +Coumadin 2.5mg daily +Biscacodyl 10mg suppository daily prn for constipation +Milk of Mag 30ml po daily prn for constipation +Melatonin 1mg po qhs prn for insomnia +MVI +Immodium 2mg po 4x daily prn for loose stool + +Discharge Medications: +1. Metolazone 2.5 mg Tablet Sig: One (1) Tablet PO once a day. +2. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +3. Allopurinol 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +6. Digoxin 125 mcg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +7. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO at bedtime. +8. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO DAILY (Daily). +9. Metoprolol Succinate 25 mg Tablet Sustained Release 24 hr +Sig: 0.5 Tablet Sustained Release 24 hr PO twice a day. +10. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) vial Inhalation Q6H (every 6 hours) as +needed for cough/sob. +11. Codeine-Guaifenesin 10-100 mg/5 mL Syrup Sig: 5-10 MLs PO +Q6H (every 6 hours) as needed for cough: Hold for sedation or RR +< 10. +12. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 14 days: last day [**11-20**]. +13. Cholestyramine-Sucrose 4 gram Packet Sig: One (1) PO BID (2 +times a day): Do not give at the same time as Levothyroxine, +metolazone and Digoxin. . +14. Warfarin 2 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: check INR every other day. +15. Torsemide 20 mg Tablet Sig: Two (2) Tablet PO BID (2 times a +day). +16. Metolazone 2.5 mg Tablet Sig: One (1) Tablet PO once a day. + +17. Sodium Chloride 0.65 % Aerosol, Spray Sig: [**12-18**] Sprays Nasal +QID (4 times a day) as needed for dry nose. +18. Heparin Flush (10 units/ml) 2 mL IV PRN line flush +PICC, heparin dependent: Flush with 10mL Normal Saline followed +by Heparin as above daily and PRN per lumen. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital1 599**] Senior Care Center - [**Location (un) 1439**] + +Discharge Diagnosis: +Acute on chronic systolic heart failure +Clostridium difficile colitis +Klebsiella Urinary Tract Infection. + + +Discharge Condition: +Dry weight 100 kg. +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Out of Bed with assistance to chair or +wheelchair + + +Discharge Instructions: +You were seen at [**Hospital1 18**] with heart failure. You were admitted to +the cardiac care unit for diuresis with Milrinone and lasix. + +We are discharging you home on the same heart failure regimen as +you were admitted with and adding metolazone 2.5mg po daily in +the am. + +You were found to have clostridium difficile colitis and were +started on flagyl. You were also found to have a urinary tract +infection and were treated with a seven day course of +ciprofloxacin. + +Weigh yourself every morning, call [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] NP if weight +goes up more than 3 lbs in 1 day or 6 pounds in 3 days. + +Followup Instructions: +Cardiology: +Provider: [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) **] [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-11-22**] +10:00 + + + +",27,2179-10-26 00:33:00,2179-11-06 17:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,CONGESTIVE HEART FAILURE," +71-year-old woman with advanced end-stage ischemic +cardiomyopathy with severe left ventricular contractile function +with lvef of 10%-15%, atrial fibrillation, [**hospital1 **]-v icd, low cardiac +output state, chronic kidney disease with past history of dvt, +pe on coumadin. + +#. nyha class 4 systolic congestive heart failure, ef 15%. with +severe volume overloaded on examination on admission. she had a +low output state with known low ef and dilated ischemic +cardiomyopathy. it was felt that she would likely need +inotropic support and she was sent to the ccu for diuresis with +milrinone gtt + lasix gtt + metolazone. the patient had +significant diuresis on this regimen. it was felt that if there +was viable myocardium currently hibernating [**1-18**] low perfusion +state, intervention may improve cardiac function. a myocardial +viability study was performed and demonstrated inferior wall +myocardial viability. lhc/rhc were performed but no +intervenable targets were appreciated; additionally, the patient +was thought to be a poor candidate for cabg/tr [**1-18**] poor targets +for grafts. it was therefore felt that the patient could only +be maximized on medical therapy. diuresis was changed to po on +[**11-5**] to her precious dose of torsemide and metolazone was added +daily to regimen. weight on discharge________. would follow +lytes every other day until stable and weekly thereafter. + +# c-diff colitis - positive c. difficile toxin assay. patient +was started on po metronidazole and cholesyramine with clinical +improvement as gauged by frequency of diarrhea, fever, and wbc +count. peak wbc 11.4. flagyl to be continued x 7 more days. +once 2 week flagyl course is finished, can consider restarting +immodium for symptomatic relief. + +# uti - patient was found to have uti [**1-18**] klebsiella pneumoniae, +pansensitive except for intermediate sensitivity to +nitrofurantoin. she was started on ciprofloxacin for 7 day +course, finished on [**11-4**]. + +#. rhythm: she has a biv icd in place and was v-paced on ecg. +she was monitored on telemetry. no events. + +#. coronaries: patient with mid-lad bms [**64**]. trop 0.04, ck-mb +negative that was likely related to chf exacerbation. she was +continued on a statin and aspirin. + +#. uri: she had been diagnosed with a uri prior to admission and +had been started on zithromax. this was held in the hospital +and sputum cultures were sent, found to be negative. pt is +currently asymptomatic. + +#. asicites: she had significant ascities on exam and she was +s/p 6l tap two weeks ago. it was felt her ascites was likely +related to right-sided heart failure and would be difficult to +resolve with diuretics. she was restarted on her home regimen of +torsemide plus metolazone as noted above. + +#. lft abnormalities: she had a mild transaminities with an ap +190, tbili 1.7. it appeared to be obstructive pattern, likely +related to congestive hepatopathy. resolved prior to discharge. + +#. h/o dvt/pe: she was anticoagulated with coumadin and has a +[**location (un) 260**] filter in place. she had a rle u/s that showed no +dvt. her inr today is _______. inr should be followed every +other day until stable and weekly thereafter. + +# hypothyroidism: continued levothyroxine. + +# code: she was full code during this hospitalization. it is +thought that she is end stage in regard to her chf with medical +treatment her only option at this time. palliative care was not +persued during this hospital stay but may be introduced by dr. +[**first name (stitle) 437**]/[**first name8 (namepattern2) **] [**last name (namepattern1) **] [**md number(3) 44664**] continues to have frequent +hospitalizations. + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Acute kidney failure, unspecified; Intestinal infection due to Clostridium difficile; Urinary tract infection, site not specified; Other ascites; Congestive heart failure, unspecified; Other specified forms of chronic ischemic heart disease; Coronary atherosclerosis of native coronary artery; Other chronic pulmonary heart diseases; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Unspecified acquired hypothyroidism; Friedl?nder's bacillus infection in conditions classified elsewhere and of unspecified site; Pressure ulcer, buttock; Pressure ulcer, stage II; Peripheral vascular disease, unspecified; Personal history of venous thrombosis and embolism; Automatic implantable cardiac defibrillator in situ]" +11638,155878.0,15383,2180-01-21,15380,133678.0,2179-09-22,Discharge summary,"Admission Date: [**2179-9-16**] Discharge Date: [**2179-9-22**] + +Date of Birth: [**2108-5-29**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1515**] +Chief Complaint: +Hypovolemia + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +71 year old F with PMH significant for advanced ischemic +cardiomyopathy EF 15%, atrial fibrillation with ICD and CKD who +presented to [**Hospital **] hospital [**2179-9-14**] for generalized weakness. +Patient reports gaining fluid (notably abdomen and lower +extremity) since early [**Month (only) 462**] and consequently toresmide was +increased and metolazone started. Per OMR notes patient's +creatinine increased to 4.7, had 15 pound weight loss (177 from +dry weight 190lb), lower blood pressures and was consequently +referred to [**Hospital **] Hospital. Due to weight loss all diuretics +were on hold since [**2179-9-7**]. Patient reports 1 month history of +increasing fatigue, weakness and shortness of breath. Denies +increase in orthopnea, PND. Denies syncope, pre-syncope or +dizziness. Denies chest pain. Denies fever, chills, cough or +increase in urination. +. +Patient's presenting vitals to [**Hospital **] Hospital were temperature +97.1, HR 70, RR 20, blood pressure 78/56. Labs notable for +creatinine of 4.7, Hematocrit 26.1, CBC 2.5, plt 60,000, INR +2.6. She was given 3 units pRBC and 2.5+ L of fluid. Cardiology +was consulted. Patient did not require pressor support. Heme was +consulted for pancytopenia felt to be secondary to hypersplenism +(demonstrated on ultrasound, new since 5/[**2177**]). Patient was +transferred to [**Hospital1 18**] CCU for further care. +. +On review of systems, she denies any prior history of stroke, +TIA, bleeding at the time of surgery, myalgias, joint pains, +cough, hemoptysis, black stools or red stools. She denies recent +fevers, chills or rigors. She denies exertional buttock or calf +pain. All of the other review of systems were negative + + +Past Medical History: +1. ischemic cardiomyopathy (EF 10-25%) s/p BiV ICD +2. Coronary artery disease status post PTCA and stenting of the +LAD in [**2164**]. +3. h/o PE secondary to DVT s/p IVC filter +4. Atrial fibrillation status post cardioversion and +biventricular pacemaker implantation. +5. HTN +6. Obesity +7. PVD +8. small VSD +9. hypothyroidism +PAST MEDICAL HISTORY: +1. CARDIAC RISK FACTORS: + Dyslipidemia +2. CARDIAC HISTORY: +-Ischemic cardiomyopathy EF %15-20 s/p biv ICD +-CAD s/p post PTCA and stenting of the LAD in [**2164**]. +-CABG: None +-PACING/ICD: atrial fibrillation on anticoagulation and ICD +biventricular pacemaker +3. OTHER PAST MEDICAL HISTORY: +chronic kidney disease +bilateral DVT s/[**Initials (NamePattern4) **] [**Last Name (NamePattern4) **] filter +pulmonary embolism +osteoarthritis +hyperkalemia + + +Social History: +Pt lives alone. She is not married. She reports a 20 pack year +history, however she quit 30 yrs ago. Denies EtOH or illicit +drug use. + + +Family History: +Mother had MI at age 50. Father in good health. Maternal uncle +died of MI in his 50's. + +Physical Exam: +Gen: alert, talkative, NAD +HEENT: supple, no LAd, Pos JVD at 12 cm +CV: RRR, 2/6 systolic murmur at apex +RESP: CTAB, no crackles or wheezes +ABD: distended, soft, pos fluid wave, umbilical hernia, +EXTR: 1+ edema bilat. right > L +NEURO: alert, oriented, +Extremeties: Groin +Pulses: + +Right: DP 1+ PT 1+ +Left: DP 1+ PT 1+ +Skin: intact +Access: PIV +Tubes: Foley d/c'ed. + + +Pertinent Results: +[**2179-9-22**] 06:50AM BLOOD WBC-3.8* RBC-3.30* Hgb-10.8* Hct-31.7* +MCV-96 MCH-32.7* MCHC-34.0 RDW-17.1* Plt Ct-95* +[**2179-9-16**] 10:40PM BLOOD Neuts-86.4* Lymphs-8.9* Monos-3.3 Eos-1.0 +Baso-0.4 +[**2179-9-22**] 06:50AM BLOOD Plt Ct-95* +[**2179-9-22**] 06:50AM BLOOD Glucose-91 UreaN-83* Creat-2.3* Na-135 +K-4.5 Cl-99 HCO3-27 AnGap-14 +. +CXR [**9-17**]: +AP chest compared to [**2175-9-20**]: + Severe cardiomegaly has progressed. Lungs are clear. Pulmonary +and +mediastinal vasculature are unremarkable and there is no pleural +effusion. +Transvenous right atrial and left ventricular pacer leads and +right +ventricular pacer defibrillator lead are unchanged in their +respective +positions. No pneumothorax. + . +Right Leg Ultrasound: [**2179-9-17**] +Grayscale color and Doppler son[**Name (NI) 1417**] of the right common +femoral, +superficial femoral, popliteal, and tibial veins were performed. +There is +normal flow, compression and augmentation seen in all of the +vessels. +IMPRESSION: No evidence of deep vein thrombosis in the right +leg. +. +Abdominal Ultrasound: [**2179-9-17**] +IMPRESSION: +1. Mild splenomegaly. +2. No thrombus identified within the IVC. +3. Large amount of ascites. + + +Brief Hospital Course: +70 year old female with severe biventricular failure with +profoundly reduced left ventricular ejection fraction of 15%, +moderate mitral regurgitation and tricuspid regurgitation with +moderate pulmonary hypertension presented to outside hospital +for fatigue and hypotension. Transferred to [**Hospital1 18**] for further +treatment of her renal failure and heart failure. +. +# PUMP: Patient with known ischemic cardiomyopathy EF 15%. New +splenomegaly concerning for worsening of EF. On admission, pt +was 7 lbs below her dry weight (190) and with poor renal +function therefore there was some concern for over-diuresis. +Gentle IVF was given and pt was allow to re-equilibrate. She +appeared to be perfusing well and did not require ionotropic +support. Her renal function improved over the course of her +stay, as did her edema with PO intake and holding her diuretics. + She was continued on her home cardiac meds including lisinopril +(decreased to 2.5/day), carvedilol and ASA. She will be +discharged on 20 mg toresemide daily for diuresis. Her Fluid +status will need to be monitored very closely as she is quite +fragile. Daily weights will need to be monitored and as her +wieght increases, she will need to have more diuretics added on. +Please contact [**Name (NI) **] [**Last Name (NamePattern1) **] NP, her heart failure NP for +further management at [**Telephone/Fax (1) 62**]. +. +# RHYTHM: Mrs [**Known lastname **] is AV paced with right bundle branch +block with underlying A Fib. She was treated with coumadin, +amiodarone and carvedilol. Her coumadin was decreased on +discharge for elevated INR, and she will follow up for repeat +INR and warfarin adjustment. She was seen by EP for evaluation +of her pacer settings, however adjustments were deferred to the +outpatient setting as changes need to be done under echo, +therefore she has an appointment scheduled this month for +adjustment of pacer settings. +. +# CORONARIES: One vessel coronary artery disease with patent +prior LAD stent. Last cath [**2171**]. No chest pain during this +admission. ASA, carvedilol and statin were continued. +. +# Acute on chronic renal failure: Her baseline creatinine is +1.3-2, during this visit creatinine peaked at 3.2 and was +thought to be pre-renal in the setting of over-diuresis. Her +renal function improved with diuretics and encouraging PO +intake. +. +# Pancytopenia: Heme consulted at OSH - felt to be secondary to +splenomegaly secondary to CHF. Platelets were stable during +this admission. Would recommend following as an outpatient with +hematology. +. +# Asymmetric lower extremity swelling: Right > Left. LENI OSH +negative. Patient reports no recent instrumentation. This was +felt to be a chronic issue related to positioning as it is no +worse than baseline and the patient tends to lie primarily on +her right side. +. +# Hypothyroid: Her levothyroxine was continued at outpatient +doses. +. +# LE muscle spasm +Not a [**Last Name **] problem, pt states started about mid [**Month (only) **]. +Interfering with activity, not able to walk now and is assist of +two to chair. Unclear how much hospitalization and +deconditioning are contributing. No improvement with hydration. +Electolytes WNL. Pt was started on Ca and will follow-up as an +outpatient. Dr. [**Last Name (STitle) **], a neurologist from [**Location (un) **] has been +contact[**Name (NI) **] to see the pt as soon as possible, her sister, will +help with setting this appt up in a timely manner. + +Medications on Admission: +- omeprazole 20 mg po qd +- simvastatin 20mg po qd +- amiodarone 200 mg qd +- carvedilol 25 mg po [**12-18**] tab in am and 1 tab pm +- Levoxyl 112 mg po qd +- recently stopped coumadin, allopurinol, colchecine, +lisinopril, Metolazone 2.5mg twice a week, torsemide 40 mg [**Hospital1 **], +digoxin + + +Discharge Medications: +1. Senna 8.6 mg Tablet Sig: 1-2 Tablets PO BID (2 times a day) +as needed for Constipation. +2. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +4. Levothyroxine 112 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain/fever. +6. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +7. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +8. Carvedilol 6.25 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +9. Warfarin 2 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: Pt's home dose is 4mg daily. Please check INR on [**9-24**]. +10. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO TID W/MEALS (3 TIMES A DAY WITH MEALS). +11. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +12. Torsemide 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +this will need to be uptitrated as weight increases over dry +weight. . +13. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +14. Simvastatin 20 mg Tablet Sig: One (1) Tablet PO once a day. + + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital1 599**] of [**Location (un) 1439**] + +Discharge Diagnosis: +Acute on Chronic systolic Congestive Heart Failure +Atrial fibrillation +Acute on chronic Kidney Disease +Pancytopenia +Hx of Bilateral DVT s/p filter + + +Discharge Condition: +stable +weight= 85.4kg. This is pt's dry weight. +BP= 80's-90's/50's. This is pts baseline +HR= 70's. +O2 sat on RA= 97% + + +Discharge Instructions: +You had too much fluid taken off and your kidneys did not +function well. We stopped all of your diuretics and gave you +some intravenous fluid. Your kidney function is now better and +we will restart the Torsemide at a very low dose. You will need +to be followed closely over the next few weeks because you will +need to have more of your medicines restarted. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] is +the CHF NP who follows you on a regular basis. She can be +reached with any questions at [**Telephone/Fax (1) 62**]. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +or 6 pounds in 3 days. +Follow a low sodium (2000mg) diet +Do not drink more than 6 cups of fluid per day or about 1.5 +liters. +We have set up an outpatient appt to see a neurologist about +your muscle spasms. +. +Medication changes: +1. Decrease your Torsemide to 20 mg daily +2. Decrease your Lisinopril to 2.5 mg daily +3. Decrease Warfarin to 2mg daily until your INR is < 3.0, then +increase to 4mg daily. +4. Do not take Colchicine or Allopurinol unless your gout comes +back (you were not taking this at home) +5. START taking Calcium and Vitamin D to prevent osteoporosis. + +Followup Instructions: +Primary Care: +[**Last Name (LF) 44661**],[**First Name3 (LF) 25**] M. Phone: [**Telephone/Fax (1) 44659**] Date/time: Please call for +an appt after you get out of rehabilitation. +Cardiology: +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-9-29**] +10:30 +Provider: [**Name10 (NameIs) 676**] CLINIC Phone:[**Telephone/Fax (1) 62**] Date/Time:[**2179-10-6**] +10:00 +. +Provider: [**First Name8 (NamePattern2) 1903**] [**Last Name (NamePattern1) 1904**], [**MD Number(3) 1240**]:[**Telephone/Fax (1) 62**] +Date/Time:[**2179-10-6**] 10:30 +Neurology: +Dr. [**Last Name (STitle) **] Phone: [**Telephone/Fax (1) 44662**] Date/Time: Office will call with +an appt. + + + +Completed by:[**2179-9-22**]",121,2179-09-16 21:42:00,2179-09-22 14:10:00,EMERGENCY,TRANSFER FROM HOSP/EXTRAM,SNF,CONGESTIVE HEART FAILURE," +70 year old female with severe biventricular failure with +profoundly reduced left ventricular ejection fraction of 15%, +moderate mitral regurgitation and tricuspid regurgitation with +moderate pulmonary hypertension presented to outside hospital +for fatigue and hypotension. transferred to [**hospital1 18**] for further +treatment of her renal failure and heart failure. +. +# pump: patient with known ischemic cardiomyopathy ef 15%. new +splenomegaly concerning for worsening of ef. on admission, pt +was 7 lbs below her dry weight (190) and with poor renal +function therefore there was some concern for over-diuresis. +gentle ivf was given and pt was allow to re-equilibrate. she +appeared to be perfusing well and did not require ionotropic +support. her renal function improved over the course of her +stay, as did her edema with po intake and holding her diuretics. + she was continued on her home cardiac meds including lisinopril +(decreased to 2.5/day), carvedilol and asa. she will be +discharged on 20 mg toresemide daily for diuresis. her fluid +status will need to be monitored very closely as she is quite +fragile. daily weights will need to be monitored and as her +wieght increases, she will need to have more diuretics added on. +please contact [**name (ni) **] [**last name (namepattern1) **] np, her heart failure np for +further management at [**telephone/fax (1) 62**]. +. +# rhythm: mrs [**known lastname **] is av paced with right bundle branch +block with underlying a fib. she was treated with coumadin, +amiodarone and carvedilol. her coumadin was decreased on +discharge for elevated inr, and she will follow up for repeat +inr and warfarin adjustment. she was seen by ep for evaluation +of her pacer settings, however adjustments were deferred to the +outpatient setting as changes need to be done under echo, +therefore she has an appointment scheduled this month for +adjustment of pacer settings. +. +# coronaries: one vessel coronary artery disease with patent +prior lad stent. last cath [**2171**]. no chest pain during this +admission. asa, carvedilol and statin were continued. +. +# acute on chronic renal failure: her baseline creatinine is +1.3-2, during this visit creatinine peaked at 3.2 and was +thought to be pre-renal in the setting of over-diuresis. her +renal function improved with diuretics and encouraging po +intake. +. +# pancytopenia: heme consulted at osh - felt to be secondary to +splenomegaly secondary to chf. platelets were stable during +this admission. would recommend following as an outpatient with +hematology. +. +# asymmetric lower extremity swelling: right > left. leni osh +negative. patient reports no recent instrumentation. this was +felt to be a chronic issue related to positioning as it is no +worse than baseline and the patient tends to lie primarily on +her right side. +. +# hypothyroid: her levothyroxine was continued at outpatient +doses. +. +# le muscle spasm +not a [**last name **] problem, pt states started about mid [**month (only) **]. +interfering with activity, not able to walk now and is assist of +two to chair. unclear how much hospitalization and +deconditioning are contributing. no improvement with hydration. +electolytes wnl. pt was started on ca and will follow-up as an +outpatient. dr. [**last name (stitle) **], a neurologist from [**location (un) **] has been +contact[**name (ni) **] to see the pt as soon as possible, her sister, will +help with setting this appt up in a timely manner. + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Acute kidney failure, unspecified; ; Ventricular septal defect; Congestive heart failure, unspecified; Other specified forms of chronic ischemic heart disease; Atrial fibrillation; Right bundle branch block; Mitral valve disorders; Other chronic pulmonary heart diseases; Diseases of tricuspid valve; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Coronary atherosclerosis of native coronary artery; Splenomegaly; Unspecified acquired hypothyroidism; Peripheral vascular disease, unspecified; Obesity, unspecified; Osteoarthrosis, unspecified whether generalized or localized, site unspecified; Spasm of muscle; Swelling of limb; Automatic implantable cardiac defibrillator in situ; Personal history of venous thrombosis and embolism; Percutaneous transluminal coronary angioplasty status; Long-term (current) use of anticoagulants]" +11860,158547.0,22991,2203-06-07,22990,162521.0,2203-05-21,Discharge summary,"Admission Date: [**2203-5-14**] Discharge Date: [**2203-5-21**] + +Date of Birth: [**2134-9-28**] Sex: F + +Service: MEDICINE + +Allergies: +Dapsone / Cyclosporine / Cefepime / Aztreonam / Azithromycin / +Vancomycin + +Attending:[**First Name3 (LF) 3913**] +Chief Complaint: +dyspnea + +Major Surgical or Invasive Procedure: +Cardiac Catheterization +Placement of tunneled right internal jugular central venous line + + +History of Present Illness: +68yo woman with h/o NHL s/p SCT in [**2199**] who presented to the ED +with acute onset shortness of breath. + +She describes waking up at 5am on the day of admission because +of severe pain from post-herpetic neuralgia in her left face. +She then began feeling very short of breath and wheezy for the +next 20 minutes. +No associated chest pain. No fevers or chills. No nausea or +vomiting. She has otherwise been feeling well. She denies any +similar symptoms in the past. She has not had any orthopnea or +prior episodes of PND. No pleuritic chest pain, no dyspnea on +exertion, no LE edema or weight gain. She has been able to mow +the lawn and go up a flight of stairs without any difficulty. No +recent travel. She does not have a personal or family history of +blood clots nor does she have a history of miscarriages. She had +tacos last night for dinner. No nausea or vomiting. + +In the ED, initial VS were: 97.5 192/101 128 24 86% RA. Her +oxygen improved to 100% on NRB. She appeared to have increased +work of breathing and she had b/l rales on exam; guaiac was +negative. BNP was elevated at [**Numeric Identifier 59336**]. The team was concerned +about the possibility of PE, but they did not obtain CTA chest +because of her advanced kidney disease. The ED team felt that PE +was high enough on their differential that they opted to treat +with a heparin gtt. They obtained a CT head, which showed some +lacunes that were new as compared to [**2199**]. Neurology was +consulted to advise whether anticoagulation would be safe. After +discussing with oncology, heparin gtt was started. Although the +team was concerned about the possibility of heart failure, she +was given SL nitroglycerin and ASA but not started on lasix or +BP medications. She did receive clindamycin and levofloxacin for +concern of a possible RLL infiltrate. She was also given +prednisone 60mg x 1 because of the possibility that she might be +adrenally insufficient on chronic steroids. + +Upon arrival to the ICU, she reported feeling comfortable. Her +pain was mild and she was not having any difficulty breathing. + + +Past Medical History: +- Large Cell Lymphoma: Diagnosed [**2197**], s/p allogeneic SCT in +[**6-13**]. Has had multiple regimens of chemotherapy c/b GVHD +- Chronic Graft vs Host Disease, mild (cutaneous, liver) +- CKD Stage V: Unclear if secondary to chemotherapy, +cyclosporin, or GVHD. Had LUE AV fistula placed but found to +have occluded left brachiocephalic vessel on fistalugram +- Hyponatremia felt to be due to increased fluid intake +- s/p Thyroidectomy for thyroid mass, pathology was benign +- Herpes zoster c/b post-herpetic neuralgia s/p nerve block + + +Social History: +Quit smoking 36 yrs ago. Very occ EtOH use. Married with two +daughters. Formerly worked in human resources at a department +store. + + +Family History: +No fam history of blood clots +Her mom deceased age 87 of cerebral hemorrhage. +Father deceased age 48 of malignant hypertension. +Aunt deceased from breast cancer. +Brother [**Name (NI) 59335**] massive MI at the age of 66. +Additional brother with hypertension and emphysema + +Physical Exam: +97.6 129/69 111 18 94% 2L +Very pleasant woman in no distress. +PERRL, EOMI. +Left lid ptosis. CN II-XII intact. +OP clear, MMM. +Neck supple, no thyroid enlargement, no adenopathy. +S1, S2, regular tachycardia, +rub. +Lung with good air movement and crackles [**12-12**] of way up b/l. +Abd soft and not tender, no palpable mass, no hepatomegaly. +Very mild asterixis R>L. Strength 5/5 in UE and LE b/l. +No LE edema. DP +2 b/l. +Dark discoloration of skin over arms and back. +LUE AV fistula with palpable thrill. + + +Pertinent Results: +LABORATORY RESULTS +==================== +On Admission: +WBC-7.2 RBC-3.53* Hgb-11.5* Hct-34.9* MCV-99* RDW-18.0* Plt +Ct-226 +-- Neuts-74.1* Bands-0 Lymphs-14.2* Monos-8.4 Eos-2.7 Baso-0.7 +PT-12.1 PTT-26.2 INR(PT)-1.0 +Glucose-114* UreaN-75* Creat-5.2* Na-127* K-4.7 Cl-96 HCO3-12* +Calcium-7.8* Phos-6.1*# Mg-2.5 +TSH-1.5 + +On Discharge: +WBC-5.8 RBC-3.15* Hgb-9.8* Hct-30.9* MCV-98 RDW-16.8* Plt Ct-169 +PT-13.0 PTT-66.9* INR(PT)-1.1 +Glucose-84 UreaN-44* Creat-3.9* Na-144 K-4.1 Cl-105 HCO3-29 +[**2203-5-20**] 06:42AM BLOOD ALT-13 AST-16 LD(LDH)-184 AlkPhos-63 +TotBili-0.2 +Calcium-9.1 Phos-2.7 Mg-2.1 + +MICROBIOLOGY +============= +Blood Cultures [**2203-5-14**]: One out of two bottles + STAPHYLOCOCCUS, COAGULASE NEGATIVE. ISOLATED FROM ONE +SET ONLY. + SENSITIVITIES PERFORMED ON REQUEST.. + Aerobic Bottle Gram Stain (Final [**2203-5-16**]): + GRAM POSITIVE COCCI IN CLUSTERS. +Blood Cultures*2 [**2203-5-16**]: No growth + +Rapid Respiratory Viral Screen [**2203-5-15**]: + **FINAL REPORT [**2203-5-17**]** + Respiratory Viral Culture (Final [**2203-5-17**]): + No respiratory viruses isolated. + Culture screened for Adenovirus, Influenza A & B, +Parainfluenza type + 1,2 & 3, and Respiratory Syncytial Virus.. + Detection of viruses other than those listed above will +only be + performed on specific request. Please call Virology at +[**Telephone/Fax (1) 6182**] + within 1 week if additional testing is needed. + Rapid Respiratory Viral Antigen Test (Final [**2203-5-15**]): + Respiratory viral antigens not detected. + SPECIMEN SCREENED FOR: ADENO,PARAINFLUENZA 1,2,3 INFLUENZA +A,B AND + RSV. + +HBsAg-NEGATIVE HBsAb-POSITIVE HBcAb-NEGATIVE HCV Ab-NEGATIVE + +OTHER STUDIES +============== +ECG [**2203-5-14**]: +Sinus tachycardia with atrial premature beats. Poor R wave +progression +in leads V1-V3. Cannot rule out old anteroseptal myocardial +infarction. +Diffuse non-specific ST-T wave abnormalities. Compared to the +previous tracing of [**2203-2-15**] there has been interval loss of R +wave in leads V2-V3. + +Chest Radiograph [**2203-5-14**]: +CONCLUSION: +Added density at the right costophrenic angle is suggestive of +an infiltrate. Blunting of the right costophrenic angle is +suggestive of a small basal effusion. + +CT Head W/O Contrast [**2203-5-14**]: +CONCLUSION: +Periventricular ischemia and scattered lacunar infarcts. No +intracranial +hemorrhage. + +CT Chest W/O Contrast [**2203-5-14**]: +CONCLUSION: +1. Bibasal effusions along with increased interstitial markings +and confluent +ground-glass opacities predominantly in the upper lobes. The +differential +considerations are fluid overload, or CHF. Please correlate +clinically. +2. Scattered tiny calcific densities in the left breast may +represent +fibroadenomas. Mammography is recommended on a non-emergent +basis. +3. No mediastinal masses. + +Transthoracic Echocardiogram [**2203-5-17**]: +Conclusions +The left atrium is normal in size. Left ventricular wall +thicknesses are normal. The left ventricular cavity size is +borderline dilated. Overall left ventricular systolic function +is probably mildly depressed (LVEF=~40-45%? %) with basal +inferior hypokinesis and possible septal hypokinesis (views are +technically suboptimal for assessment of regional wall motion). +Diastolic function could not be adquately assessed. Right +ventricular chamber size and free wall motion are normal. The +aortic valve leaflets are mildly thickened (?#). Mild (1+) +aortic regurgitation is seen. The mitral valve leaflets are +mildly thickened. Moderate to severe (3+) mitral regurgitation +is seen. The pulmonary artery systolic pressure could not be +determined. There is a small pericardial effusion. There are no +echocardiographic signs of tamponade. +--Compared with the prior study (images reviewed) of [**2203-1-6**], +the left ventricle is now more dilated, left ventricular +systolic function is more depressed with new regional wall +motion abnormality, the mitral valve chordae appear tethered, +mitral regurgitation is now much more prominent. + +Cardiac Catheterization [**2203-5-18**]: +COMMENTS: +1. Selective coronary angiography of this right dominant system +revealed +single vessel disease. The LMCA was free of critical stenoses. +The LAD +had a bifurcation lesion with a 50% stenosis in the mid-LAD and +70% +stenosis in the D1 branch. The LCx and RCA were widely patent. +2. Resting hemodynamics revealed mildly elevated right heart +filling +pressures with a mean RA of 11mmHg and severely elevated left +heart +filling pressures with a mean PCWP of 28mmHg. The cardiac index +was +preserved at 3.7 l/min/m2. +FINAL DIAGNOSIS: +1. One vessel coronary artery disease. +2. Severe diastolic ventricular dysfunction. + +Brief Hospital Course: +Ms [**Known lastname 59332**] is a 68yo woman with h/o non-Hodgkin's lymphoma s/p +SCT in [**2199**] and stage V CKD who presented with acute dyspnea in +the setting of pain, hypertension, and volume overload. + +# Dyspnea and Hypoxia: She most likely developed flash +pulmonary edema from sudden hypertension from the pain in the +setting of chronic renal disease. This was supported by CXR and +CT chest. She was given Lasix for diuresis. To cover PE (she +has had persistent tachycardia), she was started on heparin gtt. + This was discontinued as the likelihood of PE was very low +given hypoxia and tachycardia resolved with diuresis. She had no +evidence of infection or pneumonia. She takes her pentamidine +faithfully, so was unlikely to be PCP. [**Initials (NamePattern4) **] [**Last Name (NamePattern4) **] was done during +her admission to evaluate for suspected diastolic dysfunction, +however showed new inferior basal wall motion abnormality and +new moderate to severe mitral regurgitation, see below. + +# Systolic CHF: New diagnosis, on this admission. [**Last Name (NamePattern4) **] showed +EF 40-45%, but likely overestimated given significant new MR. +Likely secondary to ischemic event, either from plaque rupture +given family history, hyperlipidemia, or vasospasm. The patient +had a cardiac catheterization which did not show evidence of +occlusive disease. She was started on metoprolol, atorvastatin, +and aspirin during her hospital stay. + +# Sinus Tachycardia: Most likely this was secondary to pain and +dyspnea, unlikely to be PE. She was empirically started on a +heparin gtt, but stopped when she was no longer hypoxic. TSH +was WNL. + +# CKD stage V: On admission, the patient had mild signs of +uremia on exam and labs but denies frank symptoms apart from +volume overload. Unfortunately, occlusion of left +brachiocephalic makes left AV fistula unusable. Renal was +consulted during her hospitalization and did not think she +required acute hemodialysis. Transplant surgery was consulted +to discuss the possibility of placing another fistula on the +right. However, given the new development of CHF, this surgery +was placed on hold, and a temporary HD line was placed. +Hemodialysis was electively initiated during her +hospitalization. She had Hep C and Hep B antibiodies sent. A +PPD was placed . All hepatitis serologies were negative and +there was no induration to PPD. The patient was discharged to +outpatient dialysis. + +# Graft vs Host Disease: Pt was continued on home prednisone +after discussing with oncology. She is also on monthly +pentamidine given long term steroids. + +# Post-herpetic neuralgia: Pt was continued on home pregabalin +and nortriptyline for pain control. She will follow up in pain +clinic. + +# Small vessel ischemic disease on Head CT: Neuro was consulted +and recommended aspirin, which was started. + +# h/o thyroidectomy: TSH was WNL. Pt was continued on home +dose of levothyroxine. +. +# Hyponatremia: Chronic, will monitor +. +# Code: DNR/DNI (confirmed with patient) + + +Medications on Admission: +Prednisone 2.5mg daily (for GVHD) +Levothyroxine 125mcg daily +Nortriptyline 10mg QHS +Pregabalin 25mg [**Hospital1 **] +Calcium and vitamin D +Centrum silver +Pentamidine 300mg every month +Albuterol inhaler (almost never uses) + + +Discharge Medications: +1. Prednisone 2.5 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Nortriptyline 10 mg Capsule Sig: One (1) Capsule PO HS (at +bedtime). +4. Pregabalin 25 mg Capsule Sig: One (1) Capsule PO BID (2 times +a day). +5. Cholecalciferol (Vitamin D3) 400 unit Capsule Sig: One (1) +Capsule PO twice a day. +6. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: 1-2 puffs Inhalation Q4H (every 4 hours) as +needed for sob, wheezing. +7. Atorvastatin 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*2* +8. Metoprolol Tartrate 25 mg Tablet Sig: 0.5 Tablet PO twice a +day. +Disp:*30 Tablet(s)* Refills:*2* +9. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +10. B Complex-Vitamin C-Folic Acid 1 mg Capsule Sig: One (1) Cap +PO DAILY (Daily). +Disp:*30 * Refills:*2* +11. Multivitamin Capsule Sig: One (1) Capsule PO once a day. + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses: +Systolic and Diastolic Heart Failure +Stage V Chronic Kidney Disease +Post Herpetic Neuralgia +Secondary Diagnoses: +History of allogeneic stem cell transplant for non-Hodgkin's +Lymphoma +Chronic graft versus host disease +Hypothyroidism + +Discharge Condition: +Good, stable on room air, tolerating PO's, euvolemic + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] for evaluation of shortness of +breath. You were found to have new heart failure and volume +overload from your chronic kidney failure. You had a cardiac +catheterization which showed evidence of coronary artery +disease, but did not explain your heart failure and valve +symptoms. You were also stared on hemodialysis while you were +inpatient. + +Medication Changes: +START Metoprolol 12.5mg twice a day +START Aspirin 81mg daily +START Atorvastatin 10mg daily +START NEPHROCAPS +We discontinued your Calcium Acetate (Phoslo) and Sodium bicarb. +Please do not take this medications any more unless asked to do +so by your Nephrologist. +. +Your PPD was negative. +. +It is important that you see your docotrs for further follow up, +as we have arranged for you (see below). +. +If you experience worsening shortness of breath, chest pain, +fevers, chills or any other concerning symptoms please seek +medical attention. + +Followup Instructions: +Please set up an appointment to see your PCP Dr [**Last Name (STitle) 29827**] to +follow up on your hospitalization. + +Please keep your previously scheduled appointments: + +[**2203-5-24**] 01:30p [**Last Name (LF) **],[**First Name3 (LF) 3750**] C. + SC [**Hospital Ward Name **] CLINICAL CTR, [**Location (un) **] + HEMATOLOGY/ONCOLOGY ([**Telephone/Fax (1) 3241**]) +[**2203-5-24**] 01:30p [**Last Name (LF) **],[**First Name3 (LF) **] E. + SC [**Hospital Ward Name **] CLINICAL CTR, [**Location (un) **] + HEMATOLOGY/ONCOLOGY ([**Telephone/Fax (1) 3241**]) +[**2203-5-27**] 11:10a [**Doctor Last Name **] + ONE [**Location (un) **] PLACE ([**Location (un) **], MA), [**Location (un) **] + PAIN MANAGEMENT CENTER ([**Telephone/Fax (1) 1652**] +[**2203-5-31**] 11:20a [**Doctor Last Name **] + [**Hospital6 29**], [**Location (un) **] + CC7 CARDIOLOGY (SB) + + + +",17,2203-05-14 22:59:00,2203-05-21 15:46:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,PNEUMONIA," +ms [**known lastname 59332**] is a 68yo woman with h/o non-hodgkins lymphoma s/p +sct in [**2199**] and stage v ckd who presented with acute dyspnea in +the setting of pain, hypertension, and volume overload. + +# dyspnea and hypoxia: she most likely developed flash +pulmonary edema from sudden hypertension from the pain in the +setting of chronic renal disease. this was supported by cxr and +ct chest. she was given lasix for diuresis. to cover pe (she +has had persistent tachycardia), she was started on heparin gtt. + this was discontinued as the likelihood of pe was very low +given hypoxia and tachycardia resolved with diuresis. she had no +evidence of infection or pneumonia. she takes her pentamidine +faithfully, so was unlikely to be pcp. [**initials (namepattern4) **] [**last name (namepattern4) **] was done during +her admission to evaluate for suspected diastolic dysfunction, +however showed new inferior basal wall motion abnormality and +new moderate to severe mitral regurgitation, see below. + +# systolic chf: new diagnosis, on this admission. [**last name (namepattern4) **] showed +ef 40-45%, but likely overestimated given significant new mr. +likely secondary to ischemic event, either from plaque rupture +given family history, hyperlipidemia, or vasospasm. the patient +had a cardiac catheterization which did not show evidence of +occlusive disease. she was started on metoprolol, atorvastatin, +and aspirin during her hospital stay. + +# sinus tachycardia: most likely this was secondary to pain and +dyspnea, unlikely to be pe. she was empirically started on a +heparin gtt, but stopped when she was no longer hypoxic. tsh +was wnl. + +# ckd stage v: on admission, the patient had mild signs of +uremia on exam and labs but denies frank symptoms apart from +volume overload. unfortunately, occlusion of left +brachiocephalic makes left av fistula unusable. renal was +consulted during her hospitalization and did not think she +required acute hemodialysis. transplant surgery was consulted +to discuss the possibility of placing another fistula on the +right. however, given the new development of chf, this surgery +was placed on hold, and a temporary hd line was placed. +hemodialysis was electively initiated during her +hospitalization. she had hep c and hep b antibiodies sent. a +ppd was placed . all hepatitis serologies were negative and +there was no induration to ppd. the patient was discharged to +outpatient dialysis. + +# graft vs host disease: pt was continued on home prednisone +after discussing with oncology. she is also on monthly +pentamidine given long term steroids. + +# post-herpetic neuralgia: pt was continued on home pregabalin +and nortriptyline for pain control. she will follow up in pain +clinic. + +# small vessel ischemic disease on head ct: neuro was consulted +and recommended aspirin, which was started. + +# h/o thyroidectomy: tsh was wnl. pt was continued on home +dose of levothyroxine. +. +# hyponatremia: chronic, will monitor +. +# code: dnr/dni (confirmed with patient) + + + ","PRIMARY: [Hypertensive heart and chronic kidney disease, unspecified, with heart failure and chronic kidney disease stage V or end stage renal disease] +SECONDARY: [Acute combined systolic and diastolic heart failure; Chronic kidney disease, Stage V; Herpes zoster with other nervous system complications; Complications of transplanted bone marrow; Chronic graft-versus-host disease; Compression of vein; Hyposmolality and/or hyponatremia; Other specified cardiac dysrhythmias; Hyperpotassemia; Personal history of other lymphatic and hematopoietic neoplasms; Coronary atherosclerosis of native coronary artery; Congestive heart failure, unspecified; Other restorative surgery causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Unspecified acquired hypothyroidism; Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Polyneuropathy due to drugs; Hyperpigmentation of eyelid]" +13305,106092.0,14242,2180-01-06,14241,122062.0,2179-11-27,Discharge summary,"Admission Date: [**2179-11-21**] Discharge Date: [**2179-11-27**] + +Date of Birth: [**2123-3-4**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 943**] +Chief Complaint: +Confusion, agitation + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +Mr. [**Known lastname 42326**] is a 56 y.o. M with alcoholic cirrhosis complicated +by UGIB [**3-13**] esophageal varices s/p TIPS and TIPS redo in [**Month (only) 216**] +[**2179**], admitted for increasing confusion and agitation over the +last 3 days. The patient's relative called the GI fellow today +and reported that he has not been taking his lactulose, not +giving himself insulin, and has possibly been drinking alcohol. +He refused to come be evaluated in the ED, but GI fellow +recommended that the relative have an ambulance bring him to the +ED. +. +In the ED, initial vs were: T 98.6, P 116, BP 154/93, R 16, O2 +sat 100% RA. He was noted to be encephalopathic, agitated and +would not answer questions. Per ED physical exam, pt jaundiced +with soft, nondistended, nontender abdomen. Guaiac negative. He +spiked a temperature to 103.1 and blood cultures were sent. 3g +unasyn IV was given for empiric coverage of SBP. CT head +negative, CXR negative. Abd US showed no ascites. Received 1.5L +NS. Repleted K with 40 IV. In 2 point restraints for agitation, +was swinging at staff in the ED. Was given versed 1mg IV as +well. +. +On the floor, pt is agitated and will not cooperate with +interview or exam. +. +Review of sytems: unable to obtain +. + + +Past Medical History: +1. Alcoholic cirrhosis - hx of esophageal variceal bleed and +hepatic encephalopathy. He has had 2 TIPS procedures with stent +placement in [**2166**] and again in [**2176**]. Underwent TIPS revision in +[**8-17**] and [**9-17**]. +2. Chronic pancreatitis complicated by a parapancreatic cyst +that was infected with enteroccocus and coagulase negative +staph. On vancomycin from [**Date range (2) 42329**], then linezolid +[**Date range (1) 42330**]. +3. Type 2 DM on insulin +4. Anemia of chronic disease +5. Thrombocytopenia +6. Depression +7. Umbilical Hernia +8. History of delerium tremens + + +Social History: +He lives alone. He is currently unemployed.Has three children. +He has a history of heavy alcohol use but none since [**7-17**] (per +OMR). Smokes 1.5 PPD. No IVDU, no other illicits. + +Family History: +father - cirrhosis + +Physical Exam: +Vitals: T: 97.5, BP: 143/100, P: 109, R: 20, O2: 100% 3L, FS 243 + +General: Alert, muttering profanities (repeatedly saying ""get +the F*** out of my house""), smells of urine, not answering +questions, moving all extremities, no acute distress +Skin: jaundiced, no rash or bruising noted +HEENT: Scleral icterus, dry MM, would not open mouth +Neck: supple, JVP not elevated, no LAD +Lungs: would not cooperate with exam however lungs sound clear +to auscultation anteriorly +CV: Tachycardic, regular, normal S1 + S2, no murmurs, rubs, +gallops +Abdomen: soft, non-tender, non-distended, bowel sounds present, +no rebound tenderness or guarding +Ext: Warm, well perfused, 2+ pulses, no clubbing, cyanosis or +edema + +Pertinent Results: +Admission labs: + +[**2179-11-21**] 03:12PM BLOOD WBC-6.6 RBC-3.59* Hgb-13.4* Hct-36.4* +MCV-101* MCH-37.3*# MCHC-36.9*# RDW-16.3* Plt Ct-54* +[**2179-11-21**] 03:12PM BLOOD Neuts-80.0* Lymphs-9.8* Monos-3.9 +Eos-5.4* Baso-0.9 +[**2179-11-21**] 03:12PM BLOOD PT-17.4* PTT-35.4* INR(PT)-1.6* +[**2179-11-21**] 03:12PM BLOOD Glucose-253* UreaN-9 Creat-0.7 Na-137 +K-2.7* Cl-103 HCO3-21* AnGap-16 +[**2179-11-21**] 03:12PM BLOOD ALT-61* AST-116* LD(LDH)-317* CK(CPK)-94 +AlkPhos-432* TotBili-15.3* DirBili-8.3* IndBili-7.0 +[**2179-11-21**] 03:12PM BLOOD Lipase-12 +[**2179-11-21**] 03:12PM BLOOD cTropnT-<0.01 +[**2179-11-21**] 03:12PM BLOOD Calcium-8.6 Phos-1.2* Mg-1.4* +[**2179-11-21**] 03:00PM BLOOD Ammonia-206* +[**2179-11-21**] 03:12PM BLOOD ASA-NEG Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +[**2179-11-21**] 03:19PM BLOOD Lactate-2.5* +. +[**2179-11-21**] CT head without contrast: +1. No evidence of acute intracranial pathology. +2. Stable old right temporal lacunar type infarct. +. +[**2179-11-23**] Liver, gallbladder US: 1. Patent posterior TIPS with +wall-to-wall flow. Velocities in the proximal and mid TIPS have +decreased compared to prior. Apparent interval increase in +velocity in the posterior TIPS may be secondary to turbulence. + +2. Right and left portal vein not interrogated due to limited +patient +cooperation. +3. Cirrhotic liver with small gallstone as described. +. +[**2179-11-26**] CXR: Right basilar alveolar opacity and right pleural +effusion increased, still small, suggesting pneumonia in the +clinical context. The left lung is clear except to note basilar +atelectasis. Minimal left pleural effusion is unchanged. The +cardiomediastinal silhouette and hilar contours are otherwise +normal. +. +Discharge labs: +. +[**2179-11-27**] 05:15AM BLOOD WBC-4.9 RBC-2.79* Hgb-10.5* Hct-30.5* +MCV-110* MCH-37.7* MCHC-34.5 RDW-17.3* Plt Ct-72* +[**2179-11-26**] 05:40AM BLOOD PT-18.5* PTT-37.6* INR(PT)-1.7* +[**2179-11-27**] 05:15AM BLOOD TotBili-8.8* +[**2179-11-26**] 05:40AM BLOOD ALT-46* AST-92* LD(LDH)-333* AlkPhos-287* +TotBili-10.0* +[**2179-11-27**] 05:15AM BLOOD Calcium-8.4 Phos-2.8 Mg-1.6 + +Brief Hospital Course: +Pt is a 56 yo M with h/o EtOH cirrhosis s/p TIPS with multiple +revisions here with confusion/ agitation. +. +1. Confusion: Likely [**3-13**] Hepatic Encephalopathy as pt's relative +reports he is non-compliant with lactulose at home. The relative +also reports pt has been drinking ETOH at home although tox +screens in ED were negative. He was admitted and started on +lactulose however [**3-13**] agitation and non-compliance he had to be +given lactulose via enema. On the afternoon of [**11-22**], he became +briefly unresponsive on the floor. He continued to protect his +airway during this episode and woke up as ABG was being drawn +however he was transferred to the MICU for closer monitoring. On +the morning of [**11-23**] he was transferred back to the floor with +an NGT in place through which he was recieving lactulose. With +this, he slowly began to clear over the next several days and +his lactulose was gradually tapered to 30 ml QID at the time of +discharge. + Pt has a h/o DT with persistently elevated CIWA during the +first 4 days of this admission. Thus, withdrawl was also likely +contributing to some confusion as could benzos used to treat +withdrwal. + Pt's TIPS was initially unable to be fully assessed [**3-13**] pt's +inability to comply with exam. However, US on [**11-23**] showed the +posterior TIPS to be patent. + Finally, infection could have been a contributer to the pt's +confusion. He had a temp to 103 reportedly in ED and was put on +Ceftriaxone for presumptive SBP. However, SBP seemed unlikely +as pt had never c/o abd pain, spiked another fever, and had +limited ascites. Fever in ED could have been [**3-13**] agitation, +EtOH withdrawl and/or acute alcoholic hepatitis. Thus, +Cefriaxone was discontinued on [**11-23**]. However, fever recurred on +[**11-25**] and [**11-26**]. Blood and urine cultures were ordered and +negative. There was thought to be too little ascitic fluid to +tap. CXR showed likely aspiration PNA and the pt was put on +Ceftriaxone and Azithromycin. This was changed to PO +Levofloxacin for a planned 4 more days of antibiotic treatment +at discharge. + Of note, on [**2179-11-27**] the pt was sufficiently cleared to insist +that he be discharged and state that he would not stay in the +hospital for further treatment. He was discharged home on +Levofloxacin, Lactulose and Rifaximin. +. +2. EtOH Cirrhosis s/p TIPS: MELD on admission 22. LFT's all incr +at admission stabilized by discharge with T bili down to 8.8 on +[**11-27**]. Lasix and spironolactone were held [**3-13**] hypernatremia +early in the admission. Spironolactone was restarted prior to +discharge but lasix was not as pt was still having tenuous BP. +He should follow up with his PCP to restart this. Continued home +MVI, thiamine, folic acid, nadolol and omeprazole. +. +3. DM type [**Name (NI) **] Pt non-compliant with Insulin per relative's +report at home. He was kept on a HISS and lantus regimen here +and discharged on Lantus at the increased dose of 38 units daily +which he required here. +. +4. h/o depression- Initially help amitryptyline while pt sedated +but this was restarted prior to discharge. +. +5. Thrombocytopenia- likely [**3-13**] liver pathology, recent EtOH +use. No signs of bleeding, stable at discharge. + +Medications on Admission: +Medications: (per ED paperwork, pt not cooperative) +Amitryptypline 10 mg po qhs +Neurontin 100mg (dosing not specified) +Lactulose 30 ml po TID +Rifaximin 600 mg po BID +Furosemide 40 mg po daily +Folic acid 1 mg po daily +MVI 1 tablet po daily +Spironolactone 150 mg po daily +Omeprazole EC 20 mg daily +Lantus 34 units SQ qhs +Humalog Sliding Scale Insulin QIDACHS + + +Discharge Medications: +1. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +2. Nadolol 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +3. Levofloxacin 750 mg Tablet Sig: One (1) Tablet PO once a day +for 4 days. +Disp:*4 Tablet(s)* Refills:*0* +4. Rifaximin 200 mg Tablet Sig: Three (3) Tablet PO BID (2 times +a day). +Disp:*180 Tablet(s)* Refills:*2* +5. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO QID (4 +times a day). +Disp:*3600 ML(s)* Refills:*2* +6. Omeprazole 40 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO twice a day. +Disp:*60 Capsule, Delayed Release(E.C.)(s)* Refills:*2* +7. Spironolactone 50 mg Tablet Sig: Three (3) Tablet PO once a +day. +Disp:*90 Tablet(s)* Refills:*2* +8. Amitriptyline 10 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +9. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*2* +10. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +11. Insulin Glargine 100 unit/mL Solution Sig: 38U Subcutaneous +at bedtime. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Primary Diagnosis: +1. Hepatic Encephalopathy +2. Alcohol Withdrawal +3. Alcoholic Cirrhosis +4. Pneumonia + +Secondary Diagnosis: +1. Diabetes Mellitus, Type 2, uncontrolled +2. Depression +3. Thrombocytopenia + +Secondary Diagnosis: + + +Discharge Condition: +Stable. + + +Discharge Instructions: +You were admitted with confusion. This was likely due to both +encephalopathy as well as alcohol withdrawal. You were +monitored closely. You were restartd on lactulose to help with +your confusion. You were given medications to help prevent +alcohol withdrawal. You MUST stop drinking alcohol. + +Please continue to take your medications as prescribed. The +following changes have been made: +Please take the antibiotic, Levofloxacin 750mg daily, for +pneumonia for 5 days. + +Please keep all your medical appointments. + +If you have any of the following symptoms, please call your +doctor or go to the nearest ER: fever > 101, chest pain, +abdominal pain, shortness of breath, bright red blood per +rectum, black or red stools, vomiting red blood, confusion, or +any other concerning symptoms. + +Followup Instructions: +Please follow up with your primary care physician, [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) **] +[**Last Name (NamePattern1) 42325**]. Please call [**Telephone/Fax (1) 31553**] to reschedule. + +Provider: [**Name10 (NameIs) **] [**Hospital 1389**] CLINIC Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2179-12-22**] 8:40 +Provider: [**Name10 (NameIs) **] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2180-1-7**] 9:15 + + + +Completed by:[**2179-12-1**]",40,2179-11-21 20:59:00,2179-11-27 14:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ENCEPHALOPATHY," +pt is a 56 yo m with h/o etoh cirrhosis s/p tips with multiple +revisions here with confusion/ agitation. +. +1. confusion: likely [**3-13**] hepatic encephalopathy as pts relative +reports he is non-compliant with lactulose at home. the relative +also reports pt has been drinking etoh at home although tox +screens in ed were negative. he was admitted and started on +lactulose however [**3-13**] agitation and non-compliance he had to be +given lactulose via enema. on the afternoon of [**11-22**], he became +briefly unresponsive on the floor. he continued to protect his +airway during this episode and woke up as abg was being drawn +however he was transferred to the micu for closer monitoring. on +the morning of [**11-23**] he was transferred back to the floor with +an ngt in place through which he was recieving lactulose. with +this, he slowly began to clear over the next several days and +his lactulose was gradually tapered to 30 ml qid at the time of +discharge. + pt has a h/o dt with persistently elevated ciwa during the +first 4 days of this admission. thus, withdrawl was also likely +contributing to some confusion as could benzos used to treat +withdrwal. + pts tips was initially unable to be fully assessed [**3-13**] pts +inability to comply with exam. however, us on [**11-23**] showed the +posterior tips to be patent. + finally, infection could have been a contributer to the pts +confusion. he had a temp to 103 reportedly in ed and was put on +ceftriaxone for presumptive sbp. however, sbp seemed unlikely +as pt had never c/o abd pain, spiked another fever, and had +limited ascites. fever in ed could have been [**3-13**] agitation, +etoh withdrawl and/or acute alcoholic hepatitis. thus, +cefriaxone was discontinued on [**11-23**]. however, fever recurred on +[**11-25**] and [**11-26**]. blood and urine cultures were ordered and +negative. there was thought to be too little ascitic fluid to +tap. cxr showed likely aspiration pna and the pt was put on +ceftriaxone and azithromycin. this was changed to po +levofloxacin for a planned 4 more days of antibiotic treatment +at discharge. + of note, on [**2179-11-27**] the pt was sufficiently cleared to insist +that he be discharged and state that he would not stay in the +hospital for further treatment. he was discharged home on +levofloxacin, lactulose and rifaximin. +. +2. etoh cirrhosis s/p tips: meld on admission 22. lfts all incr +at admission stabilized by discharge with t bili down to 8.8 on +[**11-27**]. lasix and spironolactone were held [**3-13**] hypernatremia +early in the admission. spironolactone was restarted prior to +discharge but lasix was not as pt was still having tenuous bp. +he should follow up with his pcp to restart this. continued home +mvi, thiamine, folic acid, nadolol and omeprazole. +. +3. dm type [**name (ni) **] pt non-compliant with insulin per relatives +report at home. he was kept on a hiss and lantus regimen here +and discharged on lantus at the increased dose of 38 units daily +which he required here. +. +4. h/o depression- initially help amitryptyline while pt sedated +but this was restarted prior to discharge. +. +5. thrombocytopenia- likely [**3-13**] liver pathology, recent etoh +use. no signs of bleeding, stable at discharge. + + ","PRIMARY: [Hepatic encephalopathy] +SECONDARY: [Pneumonia, organism unspecified; Alcohol withdrawal; Alcoholic cirrhosis of liver; Portal hypertension; Diabetes mellitus without mention of complication, type II or unspecified type, uncontrolled; Depressive disorder, not elsewhere classified; Thrombocytopenia, unspecified; Hypopotassemia; Anemia of other chronic disease; Tobacco use disorder]" +13305,122062.0,14241,2179-11-27,14240,181328.0,2179-08-31,Discharge summary,"Admission Date: [**2179-8-27**] Discharge Date: [**2179-8-31**] + +Date of Birth: [**2123-3-4**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 330**] +Chief Complaint: +Hematemesis + +Major Surgical or Invasive Procedure: +TIPS evaluation and Redo + + +History of Present Illness: +56M with EtOH cirrhosis s/p TIPS x2 (last [**2176**]), DM2, who is +admitted to the MICU for hematemesis x1. The patient states that +this AM, he started on cymbalta for his peripheral neuropathy, +and 1 hour after taking the medication, he felt nauseous and +vomited. He vomited a few times, that were mostly bilious, but +at 11 AM, he vomited bright red blood. He states that it was a +small cup worth, mostly just streaked with blood, but concerned +enough to bring him to the ED. He denies chest pain, SOB, +lightheadedness, dizziness, abdominal pain, melena, BRBPR. Of +note, he was admitted [**6-17**] for hematemesis as well. +. +In the ED, vitals were 98.7, 129/73, 82, 18, 97% RA. He was +found to be guaiac negative. He had hypokalemia which was +repleted, and he had an abdominal US with dopplers to evaluate +his TIPS. He was given pantoprazole 40 mg IV x 1 and zofran x 1. +He was then transferred to the MICU for further evaluation. + + +Past Medical History: +1. Alcoholic cirrhosis - hx of esophageal variceal bleed and +hepatic encephalopathy. He has had 2 TIPS procedures with stent +placement in [**2166**] and again in [**2176**]. +2. Chronic pancreatitis complicated by a parapancreatic cyst +that was infected with enteroccocus and coagulase negative. On +vancomycin from [**Date range (2) 42329**] then linezolid [**Date range (1) 42330**]. +3. Type 2 DM on insulin +4. Anemia of chronic disease +5. Thrombocytopenia +6. Depression +7. Umbilical Hernia +8. History of delerium tremens + + +Social History: +He lives alone. He is currently unemployed.Has three children. +He has a history of heavy alcohol use but none since [**4-14**]. +Smokes 1.5 PPD. No IVDU, no other illicits. + + +Family History: +father - cirrhosis + +Physical Exam: +VS: 97.7 129/101 76 13 98% 2L +GEN: WD male, NAD, pleasant +HEENT: + scleral icterus; PERRL +CV: RRR- distant +LUNGS: few bibasilar rhonci. otherwise clear +ADBOMEN: soft, slightly distended, no tenderness. + dullness to +percussion. hepatic edge not palpable. guaiac negative per ED +notes +EXT: trace pedal edema +NEURO: A/O x 3; no asterxis + + +Pertinent Results: +[**2179-8-27**] 02:40PM +PT-17.3* PTT-32.4 INR(PT)-1.6* +PLT COUNT-107* +WBC-7.7 RBC-3.49* HGB-11.5* HCT-34.4* +MCV-99* MCH-33.1* MCHC-33.5 RDW-16.5* +ALBUMIN-3.2* +LIPASE-28 +ALT(SGPT)-25 AST(SGOT)-43* ALK PHOS-225* TOT BILI-4.8* +GLUCOSE-378* UREA N-10 CREAT-0.9 SODIUM-132* POTASSIUM-2.8* +CHLORIDE-95* TOTAL CO2-25 ANION GAP-15 + +[**2179-8-27**] 07:39PM HCT-31.3* + +CHEST (PA & LAT) Study Date of [**2179-8-27**] 3:49 PM +FINDINGS: +There are bibasal effusions with consolidation in the right +lower lobe. The heart and mediastinum appear unremarkable. There +is a TIPS catheter in the right upper quadrant. +The focal opacity in the right lower lobe may represent an early +pneumonia or aspiration. + +DUPLEX DOPP ABD/PEL Study Date of [**2179-8-27**] 4:26 PM +Doppler son[**Name (NI) **] for TIPS evaluation demonstrate two TIPS, one +of +them is completely occluded, the second one has appropriate +wall-to-wall flow with velocities ranging from 94-155 cm/sec, +considerably higher than prior study, suggesting in stent +stenosis. + +REVISN HEPATIC SHUNT TIPS Study Date of [**2179-8-30**] 2:41 +IMPRESSION: +1. Pre-angioplasty portal venogram demonstrating focal stenosis +of the distal (hepatic vein end) aspect of the TIPS shunt. +2. Angioplasty with 10 x 40 mm balloon with improved flow on +post-angioplasty portal venogram. +3. Drop in portosystemic gradient from 19 mmHg to 9 mmHg. + + +Brief Hospital Course: +56 yo M with Ethanol Induced Cirrhosis, Upper GI bleed s/p TIPS +who was admitted for hematemesis. + +# Hematemesis: The patient was admitted to the ICU. On initial +presentation in the ED, vitals were 98.7, 129/73, 82, 18, 97% +RA. He was found to be guaiac negative. He had hypokalemia which +was repleted, and he had an abdominal US with Dopplers to +evaluate his TIPS which was initially reported to be patent. He +was given pantoprazole 40 mg IV x 1 and Zofran x 1. He was then +transferred to the MICU for further evaluation. In the MICU, he +was started on an octreotide gtt. Serial hematocrits were +monitored and were stable not requiring any transfusions. He had +no further episodes of vomiting and was tolerating clears +without difficulty. His octreotide gtt was discontinued and he +was transferred to the Hepatorenal service. + +# Ethanol Induced Cirrhosis: The patient had a history of TIPs +and these were evaluated on admission. Although initially +reported as patent, repeat review showed evidence of stenosis +and the patient underwent a successful TIPs revision. +At the time of discharge, the patient was doing well, tolerating +a regular diet and was without pain. He was discharged with +follow-up in the [**Hospital **] clinic. + +# Pneumonia: A chest x-ray in the ED was concerning for a RLL +infiltrate suspicious for a pneumonia or aspiration. The +patient was started on Levaquin. He received a 5 day course of +antibiotics. The patient was afebrile and without evidence of +pneumonia at discharge. + +# Diabetic Neuropathy: The patient's initial presentation +appeared to be related to cymbalta which the patient was +prescribed for treatment diabetic neuropathy of his feet. The +patient was started on Amitriptyline as an alternative +medication. The patient responded well to this therapy and was +given instructions to follow-up with his primary care physician +regarding maintenance of this medication. + +Medications on Admission: +1. Folic Acid 1 mg daily +2. Furosemide 40 mg daily +3. Insulin Glargine 34 mg hs +4. Lispro SS +5. Lactulose 30mL 3-4x/day +6. Pantoprazole 40 mg PO daily +7. Pregabalin 100 mg PO BID +8. Rifaximin 400 mg PO tid +9. Aldactone 100 mg PO daily +10. Multivitamin daily +11. Sucralfate 1 gram PO QID + + +Discharge Medications: +1. Amitriptyline 10 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +Disp:*30 Tablet(s)* Refills:*2* +2. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +3. Rifaximin 200 mg Tablet Sig: Three (3) Tablet PO twice a day. + +4. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Multivitamin Tablet Sig: One (1) Tablet PO once a day. +7. Aldactone 100 mg Tablet Sig: 1.5 Tablets PO once a day. +8. Lantus 100 unit/mL Solution Sig: One (1) 34 Subcutaneous at +bedtime. +9. Insulin Lispro 100 unit/mL Solution Sig: One (1) units +Subcutaneous PRN. +10. Omeprazole 40 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses: +Hematemesis +EtOH Induced Cirrhosis +Diabetic Neuropathy +Community Acquired Pneumonia + +Seconday Diagnoses: +Diabetes + + +Discharge Condition: +Hemodynamically stable, afebrile and without pain. + + +Discharge Instructions: +You were admitted for concern for nausea, vomiting and +gastrointestinal bleeding. You did not have any bleeding while +in the hospital. Your nausea improved and appeared to be +realated to taking Cymbalta. Given your history of espohageal +bleeding, an ultrasound of your liver was performed which showed +your TIPS was occluded. This was corrected with a TIPS revision +procedure. You are have follow-up with the liver center on +[**9-14**]. Please attend this appointment as scheduled. + +In addition, you will need re-evaluation of your TIPS with an +outpatient ultrasound. This was scheduled for the same day as +your Liver center appointment ([**9-14**]). This is scheduled +for 10:30AM. You cannot eat or drink after midnight the evening +prior to this study. + +On your admission, you appeared to have a pneumonia. You have +completed a 7 day course of antibiotics. You do not appear to +have any ongoing symptoms but you should follow-up with your +primary care physician. + +You have been reporting foot pain which had been treated with +lyrica and cymbalta. Because these medications did not work for +you, we have started you on a new medication (Amitryptiline) +which seems to have helped. You are being discharged with a +prescription for this medication. Please take as directed and +follow-up with your primary care provider. + +Because of the side effects you experiencec with Cymbalata, you +should not take this medication. Please continue to take all +other previously prescribed medications as directed. + +You should call your physician or seek medical attendion if you +experience nausea, vomiting, vomiting blood, dark tarry stools, +abdominal pain, diarrhea, shortness of breath, chest pain, cough +or any other concerning symptom. + +Followup Instructions: +TIPS Ultrasound +[**2179-9-14**] +[**Hospital Ward Name 23**] Building +10:30 am + +Provider: [**Name10 (NameIs) **] [**Apartment Address(1) **] (ST-3) +GI ROOMS Date/Time:[**2179-9-14**] 8:30 + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 8507**], MD +Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2179-9-14**] 8:30 + +Provider: [**Name10 (NameIs) **],[**First Name7 (NamePattern1) **] [**Initial (NamePattern1) **] [**Last Name (NamePattern4) **] CENTER - NON BILLING +Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2179-9-13**] 9:15 + + + +Completed by:[**2179-9-2**]",88,2179-08-27 16:10:00,2179-08-31 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,UPPER GI BLEED," +56 yo m with ethanol induced cirrhosis, upper gi bleed s/p tips +who was admitted for hematemesis. + +# hematemesis: the patient was admitted to the icu. on initial +presentation in the ed, vitals were 98.7, 129/73, 82, 18, 97% +ra. he was found to be guaiac negative. he had hypokalemia which +was repleted, and he had an abdominal us with dopplers to +evaluate his tips which was initially reported to be patent. he +was given pantoprazole 40 mg iv x 1 and zofran x 1. he was then +transferred to the micu for further evaluation. in the micu, he +was started on an octreotide gtt. serial hematocrits were +monitored and were stable not requiring any transfusions. he had +no further episodes of vomiting and was tolerating clears +without difficulty. his octreotide gtt was discontinued and he +was transferred to the hepatorenal service. + +# ethanol induced cirrhosis: the patient had a history of tips +and these were evaluated on admission. although initially +reported as patent, repeat review showed evidence of stenosis +and the patient underwent a successful tips revision. +at the time of discharge, the patient was doing well, tolerating +a regular diet and was without pain. he was discharged with +follow-up in the [**hospital **] clinic. + +# pneumonia: a chest x-ray in the ed was concerning for a rll +infiltrate suspicious for a pneumonia or aspiration. the +patient was started on levaquin. he received a 5 day course of +antibiotics. the patient was afebrile and without evidence of +pneumonia at discharge. + +# diabetic neuropathy: the patients initial presentation +appeared to be related to cymbalta which the patient was +prescribed for treatment diabetic neuropathy of his feet. the +patient was started on amitriptyline as an alternative +medication. the patient responded well to this therapy and was +given instructions to follow-up with his primary care physician +regarding maintenance of this medication. + + ","PRIMARY: [Hematemesis] +SECONDARY: [Pneumonia, organism unspecified; Other complications due to other vascular device, implant, and graft; Chronic pancreatitis; Portal hypertension; Alcoholic cirrhosis of liver; Other and unspecified alcohol dependence, unspecified; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Hypopotassemia; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Anemia of other chronic disease; Thrombocytopenia, unspecified; Depressive disorder, not elsewhere classified; Umbilical hernia without mention of obstruction or gangrene; Long-term (current) use of insulin; Awaiting organ transplant status; Hypotension, unspecified; Hypoxemia; Esophageal varices in diseases classified elsewhere, without mention of bleeding]" +13305,122062.0,14241,2179-11-27,14239,126212.0,2179-07-07,Discharge summary,"Admission Date: [**2179-7-5**] Discharge Date: [**2179-7-7**] + +Date of Birth: [**2123-3-4**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 943**] +Chief Complaint: +hematemesis + +Major Surgical or Invasive Procedure: +Esophagoduodenoscopy + + +History of Present Illness: +56M with EtOH cirrhosis s/p TIPS who was admitted for +hematemesis to MICU for 24 hours and then to the floor. Pt +presented with hematemesis on [**7-5**]. Pt was hemodynamically +stable with hct of 36.4 from 39.5 (checked on [**6-29**]) and was +admitted to MICU. Liver was notified and performed an EGD in am +which showed 3 cords of grade I - II varices and esophageal +erosions without evidence of bleeding . They recommended high +dose PPI and carafate. Pt had no further episodes of hematemasis +and was started on diet. Pt's subsequently had a decrease in hct +to 29.9 at 4 pm and then 29.8 at 8 pm and 27 at 1 am on [**7-6**]. Pt +also underwent liver u/s with dopplers which showed that the +TIPS remained patent. +. +Pt currently denies dizziness, cp, sob, abd pain, nausea, +vomiting. Current vs in micu before transfer were 98.6, 93 +110/61 17 98% RA. + +Past Medical History: +1. Alcoholic cirrhosis - hx of esophageal variceal bleed and +hepatic encephalopathy. He has had 2 TIPS procedures with stent +placement in [**2166**] and again in [**2176**]. +2. Chronic pancreatitis complicated by a parapancreatic cyst +that was infected with enteroccocus and coagulase negative. On +vancomycin from [**Date range (2) 42329**] then linezolid [**Date range (1) 42330**]. +3. Type 2 DM on insulin +4. Anemia of chronic disease +5. Thrombocytopenia +6. Depression +7. Umbilical Hernia +8. History of delerium tremens + + +Social History: +He lives alone. He is currently unemployed.Has three children. +He has a history of heavy alcohol use but none since [**4-14**]. +Smokes 1.5 PPD. No IVDU, no other illicits. + + +Family History: +father - cirrhosis + +Physical Exam: +PE: T 98.6 HR 93 BP 110/61 RR 17 O2 sat 98% RA +Gen: awake, alert, NAD +HEENT: NCAT, scleral icterus, PERRL, EOMI, OP clear, MMM +CV: RRR, no m/r/g +Pulm: diffuse wheezing +Abd: soft, NT, ND +Ext: no c/c/e +no asterixis + + +Pertinent Results: +Liver US: +FINDINGS: [**Doctor Last Name **]-scale and color Doppler son[**Name (NI) 493**] images were +obtained, liver is markedly coarsened and echogenic, consistent +with known history of cirrhosis. There is a failed TIPS stent in +the right lobe of the liver without internal flow. Adjacent to +it, there is an active TIPS with wall-to- wall flow and +velocities in the proximal, mid and distal TIPS measured at 22, +30, and 66 cm/sec respectively, compared to 42, 74, and 90 +cm/sec previously. Hepatopetal flow is noted in the main portal +vein, with velocity of approximately 23 cm/sec, compared to 29 +cm/sec previously. Again noted is a cholelithiasis, without +evidence of acute cholecystitis. There is no perihepatic +ascites. There is no intra- or extra-hepatic biliary ductal +dilatation. Common duct measures 4 mm. + +IMPRESSION: Patent TIPS with wall-to-wall flow; internal +velocities are slightly lower than on the prior study. +. + +[**2179-7-7**] 05:55AM BLOOD WBC-8.0 RBC-2.58* Hgb-9.7* Hct-27.9* +MCV-108* MCH-37.5* MCHC-34.7 RDW-14.5 Plt Ct-80* +[**2179-7-6**] 01:16AM BLOOD WBC-6.9 RBC-2.48*# Hgb-9.4* Hct-27.3* +MCV-110* MCH-38.0* MCHC-34.5 RDW-14.9 Plt Ct-76* +[**2179-7-5**] 06:22AM BLOOD WBC-8.3 RBC-3.32* Hgb-12.2* Hct-36.4* +MCV-110* MCH-36.6* MCHC-33.4 RDW-14.7 Plt Ct-109* +[**2179-7-5**] 06:22AM BLOOD PT-15.5* PTT-33.8 INR(PT)-1.4* +[**2179-7-7**] 05:55AM BLOOD PT-15.5* PTT-30.7 INR(PT)-1.4* +[**2179-7-5**] 06:22AM BLOOD Glucose-430* UreaN-13 Creat-1.0 Na-127* +K-3.7 Cl-90* HCO3-22 AnGap-19 +[**2179-7-6**] 01:16AM BLOOD Glucose-346* UreaN-12 Creat-0.9 Na-129* +K-3.9 Cl-97 HCO3-25 AnGap-11 +[**2179-7-6**] 05:15AM BLOOD Glucose-394* UreaN-11 Creat-0.9 Na-128* +K-4.1 Cl-96 HCO3-24 AnGap-12 +[**2179-7-7**] 05:55AM BLOOD Glucose-237* UreaN-10 Creat-0.7 Na-130* +K-3.2* Cl-96 HCO3-25 AnGap-12 +[**2179-7-6**] 05:15AM BLOOD ALT-44* AST-82* LD(LDH)-275* AlkPhos-265* +TotBili-6.4* +[**2179-7-7**] 05:55AM BLOOD Calcium-8.5 Phos-1.8* Mg-1.7 + +Brief Hospital Course: +A/P: 56M with EtOH cirrhosis s/p TIPS presents for hematemesis +. +#. Hematemesis: s/p EGD showing nonbleeding esophageal varices +and esophageal erosions/esophagitis. There was no clear ulcer +visualized. It was felt his bleeding were due to GE junction +erosions and microtears. No overt M-W tears were visualized. +His hematocrit did drop initially which may have been dilutional +but there after remained stable. Patient should continue on PPI +and sucrafate. He will follow up in liver clinic. +. +#. DM2: - patient was continued on his home dose of lantus with +a sliding scale. +. +#. Cirrhosis: TIPS patent on ultrasound. His aldactone, lasix +were restarted on [**7-6**] with stable renal function. Patient was +continued on rifaxamin, lactulose. He was continued CTX for SBP +ppx for 3 days but due to true variceal bleeding his antibiotics +were discontinued. Patient should continue on mvi, folic acid. +. +#. Full code + + +Medications on Admission: +Meds: at home +folic acid 1 mg per day, +Furosemide 40 mg per day, +glargine insulin 36 units at night +SSI +lactulose 30 cc three to four times per day, +Protonix one tablet per day (40 mg), +Lyrica 100 mg twice a day, +rifaximin 200 mg two tablets three times a day, +Aldactone 150 mg per day +multivitamin one tablet daily. +. +Meds on transfer to [**Hospital1 18**]: +Aluminum-magnesium hydrox-simethicone 15-30cc po qid/prn +Ceftriaxone 1gm iv q24h +folic acid 1mg po qday +gabapentin 600mg po q8h +insulin SS +lactulose 30mg po tid +lyrica 100mg po bid +morphin sulfate 1mg iv q4h/prn +pantoprazole 40mg po q24 +prochlorperazine 10mg po/iv q6h/prn +rifaximin 200mg po tid +sucralfate 1mg po qid + + +Discharge Medications: +1. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Insulin Glargine 100 unit/mL Cartridge Sig: Thirty Four (34) +units Subcutaneous at bedtime. +4. Insulin Lispro 100 unit/mL Cartridge Sig: per sliding scale +Subcutaneous four times a day: inject subcutaenously four times +a day according to sliding scale. +5. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO three to +four times a day. +6. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO once a day. +7. Pregabalin 25 mg Capsule Sig: Four (4) Capsule PO BID (2 +times a day). +8. Rifaximin 200 mg Tablet Sig: Two (2) Tablet PO TID (3 times a +day). +9. Aldactone 50 mg Tablet Sig: Two (2) Tablet PO once a day. +10. Multivitamin Tablet Sig: One (1) Tablet PO once a day. +11. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO QID (4 times +a day). +Disp:*120 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Hematemesis + +Secondary: +Alcoholic cirrhosis +Chronic pancreatitis +Type 2 DM +Anemia of chronic disease +Thrombocytopenia +Depression + + +Discharge Condition: +Vitals stable. Hematocrit stable. No bleeding. + + +Discharge Instructions: +You were admitted after vomiting up a small amount of blood. You +had an EGD which showed that you have esophageal varices and +ulceration of your esophagus, but no active bleeding. + +You should continue to take all medications as prescribed. + +If you develop further bleeding, chest pain, shortness of +breath, or other concerning symptoms, you should return to the +emergency room. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Hospital 1389**] CLINIC Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2179-8-4**] 10:00 +Provider: [**Name10 (NameIs) **],[**First Name7 (NamePattern1) **] [**Initial (NamePattern1) **] [**Last Name (NamePattern4) **] CENTER - NON BILLING +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2179-7-8**] 8:30 +Provider: [**Name10 (NameIs) **] [**Hospital 1389**] CLINIC Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2179-9-15**] 8:00 + + + +Completed by:[**2179-7-9**]",143,2179-07-05 06:39:00,2179-07-07 16:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,UPPER GI BLEED," +a/p: 56m with etoh cirrhosis s/p tips presents for hematemesis +. +#. hematemesis: s/p egd showing nonbleeding esophageal varices +and esophageal erosions/esophagitis. there was no clear ulcer +visualized. it was felt his bleeding were due to ge junction +erosions and microtears. no overt m-w tears were visualized. +his hematocrit did drop initially which may have been dilutional +but there after remained stable. patient should continue on ppi +and sucrafate. he will follow up in liver clinic. +. +#. dm2: - patient was continued on his home dose of lantus with +a sliding scale. +. +#. cirrhosis: tips patent on ultrasound. his aldactone, lasix +were restarted on [**7-6**] with stable renal function. patient was +continued on rifaxamin, lactulose. he was continued ctx for sbp +ppx for 3 days but due to true variceal bleeding his antibiotics +were discontinued. patient should continue on mvi, folic acid. +. +#. full code + + + ","PRIMARY: [Hematemesis] +SECONDARY: [Chronic pancreatitis; Alcoholic cirrhosis of liver; Thrombocytopenia, unspecified; Anemia, unspecified; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled]" +13305,106092.0,14242,2180-01-06,14240,181328.0,2179-08-31,Discharge summary,"Admission Date: [**2179-8-27**] Discharge Date: [**2179-8-31**] + +Date of Birth: [**2123-3-4**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 330**] +Chief Complaint: +Hematemesis + +Major Surgical or Invasive Procedure: +TIPS evaluation and Redo + + +History of Present Illness: +56M with EtOH cirrhosis s/p TIPS x2 (last [**2176**]), DM2, who is +admitted to the MICU for hematemesis x1. The patient states that +this AM, he started on cymbalta for his peripheral neuropathy, +and 1 hour after taking the medication, he felt nauseous and +vomited. He vomited a few times, that were mostly bilious, but +at 11 AM, he vomited bright red blood. He states that it was a +small cup worth, mostly just streaked with blood, but concerned +enough to bring him to the ED. He denies chest pain, SOB, +lightheadedness, dizziness, abdominal pain, melena, BRBPR. Of +note, he was admitted [**6-17**] for hematemesis as well. +. +In the ED, vitals were 98.7, 129/73, 82, 18, 97% RA. He was +found to be guaiac negative. He had hypokalemia which was +repleted, and he had an abdominal US with dopplers to evaluate +his TIPS. He was given pantoprazole 40 mg IV x 1 and zofran x 1. +He was then transferred to the MICU for further evaluation. + + +Past Medical History: +1. Alcoholic cirrhosis - hx of esophageal variceal bleed and +hepatic encephalopathy. He has had 2 TIPS procedures with stent +placement in [**2166**] and again in [**2176**]. +2. Chronic pancreatitis complicated by a parapancreatic cyst +that was infected with enteroccocus and coagulase negative. On +vancomycin from [**Date range (2) 42329**] then linezolid [**Date range (1) 42330**]. +3. Type 2 DM on insulin +4. Anemia of chronic disease +5. Thrombocytopenia +6. Depression +7. Umbilical Hernia +8. History of delerium tremens + + +Social History: +He lives alone. He is currently unemployed.Has three children. +He has a history of heavy alcohol use but none since [**4-14**]. +Smokes 1.5 PPD. No IVDU, no other illicits. + + +Family History: +father - cirrhosis + +Physical Exam: +VS: 97.7 129/101 76 13 98% 2L +GEN: WD male, NAD, pleasant +HEENT: + scleral icterus; PERRL +CV: RRR- distant +LUNGS: few bibasilar rhonci. otherwise clear +ADBOMEN: soft, slightly distended, no tenderness. + dullness to +percussion. hepatic edge not palpable. guaiac negative per ED +notes +EXT: trace pedal edema +NEURO: A/O x 3; no asterxis + + +Pertinent Results: +[**2179-8-27**] 02:40PM +PT-17.3* PTT-32.4 INR(PT)-1.6* +PLT COUNT-107* +WBC-7.7 RBC-3.49* HGB-11.5* HCT-34.4* +MCV-99* MCH-33.1* MCHC-33.5 RDW-16.5* +ALBUMIN-3.2* +LIPASE-28 +ALT(SGPT)-25 AST(SGOT)-43* ALK PHOS-225* TOT BILI-4.8* +GLUCOSE-378* UREA N-10 CREAT-0.9 SODIUM-132* POTASSIUM-2.8* +CHLORIDE-95* TOTAL CO2-25 ANION GAP-15 + +[**2179-8-27**] 07:39PM HCT-31.3* + +CHEST (PA & LAT) Study Date of [**2179-8-27**] 3:49 PM +FINDINGS: +There are bibasal effusions with consolidation in the right +lower lobe. The heart and mediastinum appear unremarkable. There +is a TIPS catheter in the right upper quadrant. +The focal opacity in the right lower lobe may represent an early +pneumonia or aspiration. + +DUPLEX DOPP ABD/PEL Study Date of [**2179-8-27**] 4:26 PM +Doppler son[**Name (NI) **] for TIPS evaluation demonstrate two TIPS, one +of +them is completely occluded, the second one has appropriate +wall-to-wall flow with velocities ranging from 94-155 cm/sec, +considerably higher than prior study, suggesting in stent +stenosis. + +REVISN HEPATIC SHUNT TIPS Study Date of [**2179-8-30**] 2:41 +IMPRESSION: +1. Pre-angioplasty portal venogram demonstrating focal stenosis +of the distal (hepatic vein end) aspect of the TIPS shunt. +2. Angioplasty with 10 x 40 mm balloon with improved flow on +post-angioplasty portal venogram. +3. Drop in portosystemic gradient from 19 mmHg to 9 mmHg. + + +Brief Hospital Course: +56 yo M with Ethanol Induced Cirrhosis, Upper GI bleed s/p TIPS +who was admitted for hematemesis. + +# Hematemesis: The patient was admitted to the ICU. On initial +presentation in the ED, vitals were 98.7, 129/73, 82, 18, 97% +RA. He was found to be guaiac negative. He had hypokalemia which +was repleted, and he had an abdominal US with Dopplers to +evaluate his TIPS which was initially reported to be patent. He +was given pantoprazole 40 mg IV x 1 and Zofran x 1. He was then +transferred to the MICU for further evaluation. In the MICU, he +was started on an octreotide gtt. Serial hematocrits were +monitored and were stable not requiring any transfusions. He had +no further episodes of vomiting and was tolerating clears +without difficulty. His octreotide gtt was discontinued and he +was transferred to the Hepatorenal service. + +# Ethanol Induced Cirrhosis: The patient had a history of TIPs +and these were evaluated on admission. Although initially +reported as patent, repeat review showed evidence of stenosis +and the patient underwent a successful TIPs revision. +At the time of discharge, the patient was doing well, tolerating +a regular diet and was without pain. He was discharged with +follow-up in the [**Hospital **] clinic. + +# Pneumonia: A chest x-ray in the ED was concerning for a RLL +infiltrate suspicious for a pneumonia or aspiration. The +patient was started on Levaquin. He received a 5 day course of +antibiotics. The patient was afebrile and without evidence of +pneumonia at discharge. + +# Diabetic Neuropathy: The patient's initial presentation +appeared to be related to cymbalta which the patient was +prescribed for treatment diabetic neuropathy of his feet. The +patient was started on Amitriptyline as an alternative +medication. The patient responded well to this therapy and was +given instructions to follow-up with his primary care physician +regarding maintenance of this medication. + +Medications on Admission: +1. Folic Acid 1 mg daily +2. Furosemide 40 mg daily +3. Insulin Glargine 34 mg hs +4. Lispro SS +5. Lactulose 30mL 3-4x/day +6. Pantoprazole 40 mg PO daily +7. Pregabalin 100 mg PO BID +8. Rifaximin 400 mg PO tid +9. Aldactone 100 mg PO daily +10. Multivitamin daily +11. Sucralfate 1 gram PO QID + + +Discharge Medications: +1. Amitriptyline 10 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +Disp:*30 Tablet(s)* Refills:*2* +2. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +3. Rifaximin 200 mg Tablet Sig: Three (3) Tablet PO twice a day. + +4. Lasix 40 mg Tablet Sig: One (1) Tablet PO once a day. +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Multivitamin Tablet Sig: One (1) Tablet PO once a day. +7. Aldactone 100 mg Tablet Sig: 1.5 Tablets PO once a day. +8. Lantus 100 unit/mL Solution Sig: One (1) 34 Subcutaneous at +bedtime. +9. Insulin Lispro 100 unit/mL Solution Sig: One (1) units +Subcutaneous PRN. +10. Omeprazole 40 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnoses: +Hematemesis +EtOH Induced Cirrhosis +Diabetic Neuropathy +Community Acquired Pneumonia + +Seconday Diagnoses: +Diabetes + + +Discharge Condition: +Hemodynamically stable, afebrile and without pain. + + +Discharge Instructions: +You were admitted for concern for nausea, vomiting and +gastrointestinal bleeding. You did not have any bleeding while +in the hospital. Your nausea improved and appeared to be +realated to taking Cymbalta. Given your history of espohageal +bleeding, an ultrasound of your liver was performed which showed +your TIPS was occluded. This was corrected with a TIPS revision +procedure. You are have follow-up with the liver center on +[**9-14**]. Please attend this appointment as scheduled. + +In addition, you will need re-evaluation of your TIPS with an +outpatient ultrasound. This was scheduled for the same day as +your Liver center appointment ([**9-14**]). This is scheduled +for 10:30AM. You cannot eat or drink after midnight the evening +prior to this study. + +On your admission, you appeared to have a pneumonia. You have +completed a 7 day course of antibiotics. You do not appear to +have any ongoing symptoms but you should follow-up with your +primary care physician. + +You have been reporting foot pain which had been treated with +lyrica and cymbalta. Because these medications did not work for +you, we have started you on a new medication (Amitryptiline) +which seems to have helped. You are being discharged with a +prescription for this medication. Please take as directed and +follow-up with your primary care provider. + +Because of the side effects you experiencec with Cymbalata, you +should not take this medication. Please continue to take all +other previously prescribed medications as directed. + +You should call your physician or seek medical attendion if you +experience nausea, vomiting, vomiting blood, dark tarry stools, +abdominal pain, diarrhea, shortness of breath, chest pain, cough +or any other concerning symptom. + +Followup Instructions: +TIPS Ultrasound +[**2179-9-14**] +[**Hospital Ward Name 23**] Building +10:30 am + +Provider: [**Name10 (NameIs) **] [**Apartment Address(1) **] (ST-3) +GI ROOMS Date/Time:[**2179-9-14**] 8:30 + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 8507**], MD +Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2179-9-14**] 8:30 + +Provider: [**Name10 (NameIs) **],[**First Name7 (NamePattern1) **] [**Initial (NamePattern1) **] [**Last Name (NamePattern4) **] CENTER - NON BILLING +Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2179-9-13**] 9:15 + + + +Completed by:[**2179-9-2**]",128,2179-08-27 16:10:00,2179-08-31 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,UPPER GI BLEED," +56 yo m with ethanol induced cirrhosis, upper gi bleed s/p tips +who was admitted for hematemesis. + +# hematemesis: the patient was admitted to the icu. on initial +presentation in the ed, vitals were 98.7, 129/73, 82, 18, 97% +ra. he was found to be guaiac negative. he had hypokalemia which +was repleted, and he had an abdominal us with dopplers to +evaluate his tips which was initially reported to be patent. he +was given pantoprazole 40 mg iv x 1 and zofran x 1. he was then +transferred to the micu for further evaluation. in the micu, he +was started on an octreotide gtt. serial hematocrits were +monitored and were stable not requiring any transfusions. he had +no further episodes of vomiting and was tolerating clears +without difficulty. his octreotide gtt was discontinued and he +was transferred to the hepatorenal service. + +# ethanol induced cirrhosis: the patient had a history of tips +and these were evaluated on admission. although initially +reported as patent, repeat review showed evidence of stenosis +and the patient underwent a successful tips revision. +at the time of discharge, the patient was doing well, tolerating +a regular diet and was without pain. he was discharged with +follow-up in the [**hospital **] clinic. + +# pneumonia: a chest x-ray in the ed was concerning for a rll +infiltrate suspicious for a pneumonia or aspiration. the +patient was started on levaquin. he received a 5 day course of +antibiotics. the patient was afebrile and without evidence of +pneumonia at discharge. + +# diabetic neuropathy: the patients initial presentation +appeared to be related to cymbalta which the patient was +prescribed for treatment diabetic neuropathy of his feet. the +patient was started on amitriptyline as an alternative +medication. the patient responded well to this therapy and was +given instructions to follow-up with his primary care physician +regarding maintenance of this medication. + + ","PRIMARY: [Hematemesis] +SECONDARY: [Pneumonia, organism unspecified; Other complications due to other vascular device, implant, and graft; Chronic pancreatitis; Portal hypertension; Alcoholic cirrhosis of liver; Other and unspecified alcohol dependence, unspecified; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Hypopotassemia; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Anemia of other chronic disease; Thrombocytopenia, unspecified; Depressive disorder, not elsewhere classified; Umbilical hernia without mention of obstruction or gangrene; Long-term (current) use of insulin; Awaiting organ transplant status; Hypotension, unspecified; Hypoxemia; Esophageal varices in diseases classified elsewhere, without mention of bleeding]" +15853,111874.0,23002,2174-12-02,23001,199461.0,2174-11-25,Discharge summary,"Admission Date: [**2174-11-21**] Discharge Date: [**2174-11-25**] + +Date of Birth: [**2098-2-28**] Sex: M + +Service: SURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 6346**] +Chief Complaint: +Abdominal pain, Nausea/Vomiting + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +76 year-old gentleman with known ventral hernia presents with +vomiting and abdominal pain. The abdominal pain began suddenly +at 6PM to the left of midline where the patient has known about +a hernia for ""years."". The pain was persistent and rated [**9-5**]. +The EMTs came to pick the patient up and witnessed him vomit +approximately 500 cc of dark emesis. Upon arrival to [**Hospital1 18**], the +patient is still in pain, but pain is relieved with morphine. He +is still nauseated. He denies fevers/chills. Last BM was +yesterday and he is not passing flatus. + + +Past Medical History: +1. He had a ventral hernia repair in [**2174**] +that has subsequently recurred his hernia. + +2. sub-pubic lipoma + +3. ? back surgery in the past + +4. Severe Aortic Stenosis + +Social History: +He is a veteran of the Korean war. He worked for [**Location (un) **] +township until the age of 30 when he retired due to back pain. +He lives alone. He drinks 1 case of beer per week and [**1-28**] quarts +of wine per week. He has a 60 pack-year smoking history, but he +quit 20 years ago. + + +Family History: +His family history is only significant for hypertension. + +Physical Exam: +On Admission + +VS: T 97.2, HR 89, BP 158/70, RR 20, 94%RA +GEN: NAD, A&O x 3 +LUNGS: Clear B/L +CV: Irregularly irregular, nl S1 and S2 +ABD: Soft, slightly TTP to left of midline where there is a +prominent hernia, hernia is reducible when patient relaxes but +reexpands immediately after, ND, no guarding, no rebound, no +palpable groin hernias +RECTAL: Guaiac neg +EXT: 1+ edema of LE B/L + +At Discharge + +96.6 120 110/80 20 96% RA +Gen: A&Ox3, talkative and pleasant +Lungs: decreased b/s at bases b/l +CV: irreg irreg, tachycardic, [**5-2**] blowing systolic murmur at +left sternal border +Abd: soft, non-tender, easily reducable ventral hernia. Inguinal +hernia firm, unchanged from admission +Ext: no edema + +Pertinent Results: +[**2174-11-20**] 10:45PM BLOOD WBC-5.7 RBC-4.44* Hgb-14.9 Hct-44.4 +MCV-100* MCH-33.5* MCHC-33.6 RDW-14.4 Plt Ct-113* +[**2174-11-21**] 09:05AM BLOOD WBC-2.3*# RBC-3.87* Hgb-13.5* Hct-38.9* +MCV-100* MCH-34.8* MCHC-34.7 RDW-13.7 Plt Ct-91* +[**2174-11-23**] 12:45PM BLOOD WBC-4.9 RBC-3.82* Hgb-12.7* Hct-38.1* +MCV-100* MCH-33.4* MCHC-33.4 RDW-14.2 Plt Ct-111* +[**2174-11-24**] 02:19AM BLOOD WBC-5.2 RBC-3.74* Hgb-13.0* Hct-37.5* +MCV-100* MCH-34.7* MCHC-34.6 RDW-13.6 Plt Ct-96* +[**2174-11-20**] 10:45PM BLOOD PT-13.8* PTT-25.7 INR(PT)-1.2* +[**2174-11-20**] 10:45PM BLOOD Glucose-151* UreaN-25* Creat-1.9* Na-139 +K-5.6* Cl-99 HCO3-26 AnGap-20 +[**2174-11-21**] 09:05AM BLOOD Glucose-129* UreaN-25* Creat-1.8* Na-139 +K-4.6 Cl-101 HCO3-27 AnGap-16 +[**2174-11-23**] 12:45PM BLOOD Glucose-138* UreaN-24* Creat-1.5* Na-139 +K-4.3 Cl-107 HCO3-24 AnGap-12 +[**2174-11-24**] 02:19AM BLOOD Glucose-118* UreaN-28* Creat-1.4* Na-141 +K-4.1 Cl-108 HCO3-22 AnGap-15 +[**2174-11-21**] 12:50PM BLOOD CK(CPK)-99 +[**2174-11-23**] 12:10PM BLOOD CK(CPK)-288* +[**2174-11-24**] 02:19AM BLOOD CK(CPK)-245* +[**2174-11-21**] 12:50PM BLOOD CK-MB-NotDone cTropnT-0.02* +[**2174-11-23**] 12:10PM BLOOD CK-MB-7 cTropnT-0.02* +[**2174-11-24**] 02:19AM BLOOD CK-MB-9 +[**2174-11-23**] 05:26PM BLOOD Type-ART pO2-64* pCO2-35 pH-7.43 +calTCO2-24 Base XS-0 +[**2174-11-24**] 02:34AM BLOOD Type-ART pO2-62* pCO2-32* pH-7.45 +calTCO2-23 Base XS-0 +[**2174-11-20**] 10:54PM BLOOD Lactate-3.6* +[**2174-11-24**] 02:34AM BLOOD Lactate-1.3 + +Brief Hospital Course: +Patient was admitted to the general surgery service from the +emergency room on [**11-21**] with symptoms of a small bowel +obstruction secondary to a large ventral hernia. He was +decompressed with an NG tube and given IV fluids for +resuscitation. His large ventral hernia was tender but able to +be manualy decompressed. +On hospital day 2 the patient stated he was feeling better and +self-d/c'd his NG tube, he refused to have another placed. He +agreed to be seen by cardiology and plastic surgery for +pre-operative consultation regarding his large ventral hernia, +but after learning that a possible component separation would be +necessary and that his cardiovascular status was significantly +compromised, was adamently uninterested in any surgical +intervention. Cardiology performed a TTE that revealed severe +aortic valve stenosis with a valvular area of 0.6cm, and stated +he would be a very high risk operative candidate, recommending a +valvuloplasty prior to any elective surgery. +The patient understood his condition and given that he was +feeling better was adament about not undergoing further testing +or intervention. He was evaluated by psychiatry and deemed +competent to make such decisions on his own. +On hospital day 3 he was transferred to the ICU for respiratory +distress, desaturation and tachypnea. He was placed on a face +mask in the ICU but was clear about his wishes to be DNR/DNI, +however he did not officially sign the DNR/DNI form. His wishes +were corroborated with his only out of hospital contact, [**Name (NI) 9485**] +[**Name (NI) 59352**], a family friend. After rate control for his afib, he was +tranferred back to the floor on hospital day 4, tolerating a +regular diet and sating in the mid 90s on RA. The palliative +care team, social work and case management were all [**Name (NI) 653**] +regarding dispo planning for this gentleman, and a tentative +plan for home hospice in the form of VNA was made. He was +insistent on discharge on HD3 but agreed to stay overnight for +on more day to sort out his support at home. Several friends +were [**Name (NI) 653**] who agreed to check in on the patient, he refused +VNA or home hospice. +At the time of discharge on HD 5 he was tolerating a regular +diet, his vital signs were normal and the patient, nursing and +medical staff agreed on a plan for him to return home with +regular visits from his several friends listed above. + +Medications on Admission: +doxazosin, lisinopril, simvastatin + +Discharge Medications: +1. Doxazosin 1 mg Tablet Sig: Two (2) Tablet PO HS (at bedtime). + +2. Metoprolol Tartrate 50 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +3. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Simvastatin 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Coumadin 2 mg Tablet Sig: One (1) Tablet PO once a day: One +tablet by mouth Monday-Saturday. Two tablets by mouth on +Sundays. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Severe Aortic Stenosis. +Ventral hernia. +Resolved small bowel obstruction. + + +Discharge Condition: +Stable. Tolerating regular diet. Not currently obstructed. + + +Discharge Instructions: +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight goes up more +than 3 lbs. Adhere to 2 gm sodium diet. + +Please call your doctor or nurse practitioner or return to the +Emergency Department for any of the following: + +*You experience new chest pain, pressure, squeezing or +tightness. + +*New or worsening cough, shortness of breath, or wheeze. + +*If you are vomiting and cannot keep down fluids or your +medications. + +*You are getting dehydrated due to continued vomiting, diarrhea, +or other reasons. Signs of dehydration include dry mouth, rapid +heartbeat, or feeling dizzy or faint when standing. + +*You see blood or dark/black material when you vomit or have a +bowel movement. + +*You experience burning when you urinate, have blood in your +urine, or experience a discharge. + +*Your pain is not improving within 8-12 hours or is not gone +within 24 hours. Call or return immediately if your pain is +getting worse or changes location or moving to your chest or +back. + +*You have shaking chills, or fever greater than 101.5 degrees +Fahrenheit or 38 degrees Celsius. + +*Any change in your symptoms, or any new symptoms that concern +you. + +Please resume all regular home medications , unless specifically +advised not to take a particular medication. Also, please take +any new medications as prescribed. + + +Followup Instructions: +Please call Dr [**First Name (STitle) 2819**] office to schedule an appointment +[**Telephone/Fax (1) 2998**] if you would like to follow-up with him for +elective surgery. + + + +",7,2174-11-21 03:19:00,2174-11-25 18:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,BOWEL OBSTRUCTION," +patient was admitted to the general surgery service from the +emergency room on [**11-21**] with symptoms of a small bowel +obstruction secondary to a large ventral hernia. he was +decompressed with an ng tube and given iv fluids for +resuscitation. his large ventral hernia was tender but able to +be manualy decompressed. +on hospital day 2 the patient stated he was feeling better and +self-d/cd his ng tube, he refused to have another placed. he +agreed to be seen by cardiology and plastic surgery for +pre-operative consultation regarding his large ventral hernia, +but after learning that a possible component separation would be +necessary and that his cardiovascular status was significantly +compromised, was adamently uninterested in any surgical +intervention. cardiology performed a tte that revealed severe +aortic valve stenosis with a valvular area of 0.6cm, and stated +he would be a very high risk operative candidate, recommending a +valvuloplasty prior to any elective surgery. +the patient understood his condition and given that he was +feeling better was adament about not undergoing further testing +or intervention. he was evaluated by psychiatry and deemed +competent to make such decisions on his own. +on hospital day 3 he was transferred to the icu for respiratory +distress, desaturation and tachypnea. he was placed on a face +mask in the icu but was clear about his wishes to be dnr/dni, +however he did not officially sign the dnr/dni form. his wishes +were corroborated with his only out of hospital contact, [**name (ni) 9485**] +[**name (ni) 59352**], a family friend. after rate control for his afib, he was +tranferred back to the floor on hospital day 4, tolerating a +regular diet and sating in the mid 90s on ra. the palliative +care team, social work and case management were all [**name (ni) 653**] +regarding dispo planning for this gentleman, and a tentative +plan for home hospice in the form of vna was made. he was +insistent on discharge on hd3 but agreed to stay overnight for +on more day to sort out his support at home. several friends +were [**name (ni) 653**] who agreed to check in on the patient, he refused +vna or home hospice. +at the time of discharge on hd 5 he was tolerating a regular +diet, his vital signs were normal and the patient, nursing and +medical staff agreed on a plan for him to return home with +regular visits from his several friends listed above. + + ","PRIMARY: [Ventral, unspecified, hernia with obstruction] +SECONDARY: [Aortic valve disorders; Atrial fibrillation; Unspecified psychosis; Chronic kidney disease, unspecified; Other and unspecified hyperlipidemia; Lumbago; Other chronic pain; Hypertrophy (benign) of prostate without urinary obstruction and other lower urinary tract symptom (LUTS); Personal history of venous thrombosis and embolism]" +18082,181163.0,11814,2156-03-29,11813,164053.0,2155-11-29,Discharge summary,"Admission Date: [**2155-10-29**] Discharge Date: [**2155-11-29**] + + +Service: MEDICINE + +Allergies: +Sulfa (Sulfonamides) / Erythromycin Base / Lactose Intolerance + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +Left foot ulcer/cellulitis + + +Major Surgical or Invasive Procedure: +Picc line + +History of Present Illness: +Mrs. [**Known lastname 31102**] is a [**Age over 90 **] yo with MMM who was admitted on [**2155-10-29**] +with a left foot ulcer. She was treated w/ PO abx as outpt +without much improvement and, thus, was admitted for IV abx and +eval for possible osteo. MR foot on [**11-1**] without clear evidence +of osteo, though it could not be ruled out. ESR & CRP elevated +in past (not checked on this admission). Superficial cx + for +MRSA. Podiatry & vascular consulted. Non-invasives performed, +revealing severe PVD of left foot. Angio/possible surgical tx +was being discussed when pt fell while in hospital. + +Unfortunately, on [**2155-11-4**], pt found ""slumped in bathroom"", +apparently after trying to ambulate on her own. No reported +LOC/loss of bowel or bladder conintence. Fall thought to be +mechanical. Head CT showed acute left frontal subdural +hematoma, without evidence of shift of midline structures, as +well as left frontal subgaleal hematoma. Neurosurgery saw pt, +no intervention recommended. Anti-coagulants/anti-platelet +agents held. Platelets transfused (?). Repeat head CT on [**11-5**] +showed expansion from 4mm to 8mm. Neurosurg still felt no +intervention necessary given risk. Repeat scan on [**11-6**] & [**11-7**] +showed stable SDH. + +On [**11-7**] PM, following repeat CT head, pt reportedly had +decreased MS, desaturation to 88% on RA, and fevers to 101.9. +Triggered for desaturation to 88% on RA. O2 sats improved to +92-93% on 2-3L NC. She was described as rousable to sternal +rub. Pt given ethacrynic acid to diurese. Morning of [**11-8**], pt +received her metoprolol, then had BP 70s/30s. Was noted to be +unrousable to painful stimuli. Peripheral dopamine was started +and the MICU team was contact[**Name (NI) **] for transfer + +Pt arrived in MICU on dopamine. She received bolus of ~1L and +pressure improved to 110s to 120s systolic. Dopamine was +stopped. A-line was place. + +She was eventually transferred back out to the medicine floor. +She was started on levofloxacin/flagyl for presumed aspiration +PNA and screened for rehab. She was discharged to rehab the +morning of [**2155-11-29**]. + +Past Medical History: +1) Diabetes mellitus (Hgb A1C 5.8% in [**2-8**]) +2) Frequent UTI +3) Gastroesophageal reflux disease +4) S/p CVA w/residual mild R hemiparesis +5) Osteoporosis +6) Mild cognitive impairment +7) Depression/Anxiety +8) Osteoarthritis +9) Hypothyroidism (last TSH 2.8 in [**11-7**]) +10) Chronic diarrhea +11) COPD, on night O2 at home (FEV1 0.88 (73% pred), FVC 1.2, +elevated EV1/VC ratio in [**1-6**]), no prior intubations, was +placed on steroid taper at last admission in [**3-11**]. +12)Diastolic CHF +13)Coronary Artery Disease with cath [**1-8**], no intervention +14)s/p admission for fall at home discharged on [**2155-8-29**] + + +Social History: +Smoked 2ppd until [**2131**]. [**2-4**] glass of wine 3-4x/week. Worked as a +secretary. Independent with ADLs, not IADL. Has 24 hour +caretaker. [**Name (NI) **] (daughter) is the Healthcare proxy. + + +Family History: +Non-contributory + +Physical Exam: +Vitals: T 95.6 HR 74 BP 89/38 R 20 97% 3LNC +Gen: pale, elderly cachectic female lying in bed, does not +respond to voice, but does withdraw to painful stimuli +HEENT: NCAT, sclerae anicteric/noninjected, EOMI, PERRL, OP +clear, uvula midline, dry MM +Neck: JVP ~5 cm, no LAD +CV: distant heart sounds, nl S1/S2, [**2-8**] diastolic and systolic +non radiating murmur noted +Lungs: decreased breath sounds at the bases, otherwise CTA, no +wheezes +Ab: soft, NTND, NABS, no HSM by percussion, no rebound or +guarding +Extrem: no c/c/e +Skin: warm, lef foot, inner surface of big toe w/ mild erythema +surround scabbed area, no fluctance or drainage +Neuro: not speaking, does not allow her eyes to be opened, will +move all extremities when stimulated by pain + +Pertinent Results: +[**2155-10-29**] Foot MR - Edema involving the lateral aspect of the +first metatarsal head and to a lesser extent the base of the +first toe proximal phalanx. The appearance is nonspecific. +Considerations include changes related to altered mechanics and +trauma. Osteomyelitis is not excluded. + +[**2155-11-4**] CT Head - Study limited by motion artifact. New acute +left frontal subdural hematoma seen, without evidence of shift +of midline structures. Left frontal subgaleal hematoma. + +[**2155-11-9**] MR [**Name13 (STitle) 430**] - +1. Left subdural hematoma. +2. No evidence of acute infarct. +3. Marked cerebral atrophy. +4. Multiple nonspecific FLAIR hyperintense foci in the +periventricular and deep white matter likely represent chronic +microvascular ischemic changes. + +[**2155-11-24**] CT Head - Appropriate evolution of the left frontal +subdural hematoma without evidence of new hemorrhage. + +[**2155-11-25**] LENI - No deep vein thrombosis seen in either leg. + + +Brief Hospital Course: +[**Age over 90 **] F with with COPD on home 02, h/o CVA, DM II, diastolic CHF, +MRSA +, admitted with foot ulcer, hospitalization complicated by +fall w/ SDH, fevers, & worsening mental status. + +# SDH: [**Hospital **] hospital course was complicated by SDH which was +sustained s/p fall. Initial CT showed 4mm hematoma, next CT on +[**11-5**] showed expansion to 8mm, repeats on [**11-6**] & [**11-7**] have been +stable. Neurosurgery recommended supportive care only. Held +anti-coagulation/anti-platelet agents. Repeated CTs showed no +changes. EEG no signs of seizure ativity. Keppra given for +seizure prophlaxis but stoped as it was thought to be +contributing to MS changes. Repeat CT scans stable and examined +by neurosurgery. Patient was restarted on ASA per NSG recs. +She was seen by neurosurgery prior to discharge and had plans to +see them in clinic in [**2-4**] weeks. At that time the patient will +need a repeat head CT. + +# Altered mental status: per family pt has been ""unresponsive""/ +minimally responsive for two days, since her fall. At baseline, +pt is interactive & talkative, though demented. Has been +minimally responsive voice & painful stimili for ~24hr. [**2155-11-8**] +AM not responding to painful stimuli. Suspect that some of MS +change is due to effect of SDH, though there is no shift/mass +effect. Could be some infectious component, though no clear +source apart from her L foot ulcer, which appears to be +improving. No metabolic abnormalities to explain change. Could +be related to hypothyroidism. Treated for potential infections. +Pt became more alert without any intervention. At the time of +discharge, the patient was answering questions with yes or no +answers and following basic commands. + +# Hypotension: Patient had episode of hypotension while in the +hospital. She was transfered to the ICU briefly where she +recieved fluids and was briefly on dopamine. Thought to be +related to hypovolemia / antihypertension medications. She was +rehydrated in the MICU and her blood pressures improved. She +was slowly restarted on her home BP meds as her BP tolerated. + +#Pneumonia: Patient was noted to have episodes of tachypnea and +tachycardia. Cxray revealed a infiltrate. Suspicion for +aspiration pneumonia and patient was started on flagyl and +levoquin on [**2155-11-27**]. She will need to complete a 10 day course +(last day should be [**2155-12-6**]). + +#Foot ulcer: MRI w/o definitive evidence of osteo. She will be +treated with a 6 week total course of Vancomycin for the +infection. Wound swab postive for MRSA. Course to end on +[**2155-12-10**]. Dosing based on levels (goal vanco trough >15; +currently on q 36hr dosing). + +# COPD: on home O2, 2L, w/ baseline 02 sats 90-95% per family. +She was continued on Nebs and O2 as needed while hospitalized. + +# CAD: Patient was ruled out during hypotensive episode. Cardiac +enzymes remained negative and her EKGS were without evidence of +acute events. She was continued on ASA but plavix was held per +neurosurgery recs. + +# Anemia: Has anemia of chronic disease at baseline--confirmed +by iron studies this admission. Hct has slowly dropped from ~37 +on admission to 24 and stabilized at 27. Causes likely include +possible slow GIB, repeated phlebotomy, and acute illness. No +gross hemorrhage, apart from SDH, which is stable. Hemolysis +labs negative. She was noted to be guiac positive during this +admission which will need futher workup as an outpatient. She +did not require any tranfusions. + +# Diastolic CHF: EF 50-55%. JVP ~5. Appears euvolemic on exam. + Patient's metoprolol was held after her transfer to the ICU. +She was continued on her lisinopril without signs of volume +overload. Her metoprolol was restarted on the day of discharge. + +# Hyponatremia - patient was noted to be mildly hyponatermic at +times during admission. Sodium responded to gentle IV hydration +with normal saline. + +# Hypothyroid: She was continued on her home levothyroxine. + +# DM2: At home patient controlled with diet and glipizide. She +was covered with sliding scale while in house. Sugars were well +controlled. Because her sugars were well controlled her +glipizide was not restarted at the time of discharge. + +# FEN: Patient was started on tube feeds. She failed multiple +speech and swallow evaluations. After discussion with patient's +family, a G/J tube was placed. + + +Medications on Admission: +Ipratropium Bromide Neb 1 NEB IH Q8H +Fluticasone-Salmeterol (100/50) 1 INH IH [**Hospital1 **] +Aspirin 81 mg PO daily +Fluoxetine HCl 20 mg PO daily +Glipizide 2.5 mg PO daily +Metoprolol 12.5 mg PO BID +Levothyroxine Sodium 50 mcg PO daily +Lisinopril 2.5 mg PO daily +Lorazepam 0.5 mg PO daily + + +Discharge Medications: +1. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +2. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +3. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +4. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO BID (2 times a day). +5. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +6. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +7. Levothyroxine 50 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +8. Hexavitamin Tablet Sig: One (1) Cap PO DAILY (Daily). +9. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 10 days: Please continue until [**12-7**]. +10. Levofloxacin 250 mg Tablet Sig: One (1) Tablet PO Q24H +(every 24 hours) for 10 days: Please continue until [**12-7**]. +11. Ipratropium Bromide 0.02 % Solution Sig: One (1) neb +Inhalation every eight (8) hours as needed. +12. PICC Care +PICC care per protocol +13. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gm Intravenous Q36H (every 36 hours): Please continue until [**12-10**]. Please check troughs - goal 15-20. +14. Metoprolol Tartrate 25 mg Tablet Sig: 0.5 Tablet PO twice a +day: please hold for SBP<90 or HR<55. +15. Fluoxetine 20 mg Capsule Sig: One (1) Capsule PO once a day. + + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +Primary: +1. Traumatic left parietal SDH. +2. Delirium. +3. LLE 1st MTP cellulitis/ulcer. +4. Cachexia + +Secondary: +1. Diabetes Mellitus Type II. +2. Anemia of Chronic Disease. +3. Diastolic Heart Failure. +4. Moderate RCA and D1 coronary artery disease. +5. Hypertension. +6. Gastroesophageal reflux disease +7. S/P Pontine CVA w/residual mild right hemiparesis +8. Osteoporosis +9. Dementia. +10. Depression/Anxiety +11. Osteoarthritis +12. Hypothyroidism +13. COPD on Home 02 +14. Chronic diarrhea. +15. MRSA + + +Discharge Condition: +Stable, maintaining oxygen saturation, mental status improved + + +Discharge Instructions: +You were seen in the hospital for treatment of cellulitis. +During the hospitalization you had a subdural hemorrhage. +Neurosurgery followed you while in the hospital and no surgery +was indicated. You will follow up with Dr. [**First Name (STitle) **] from +neurosurgery in two weeks and have a repeat CT scan. You were +also treated for aspiration pneumonia. Please finish your +course of antibiotics. + +Please keep the appointments listed below + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. + +The following changes have been made to your home medications. +1. Your lisinopril was increased from 2.5mg to 5mg daily +2. We have been holding your glipizide while you were in the +hospital. Your sugars have been well controlled. +3. We also have been holding your ativan. +4. You have 2 new antibiotics that need to be continued to +another 7 days after you are discharged. These antibiotics are +called levofloxacin and flagyl. +5. You are on vancomycin for a total of 6 weeks for a foot +ulcer. + +If you have any change in mental status, new neurological +symptoms, shortness of breath, or other concerning symptoms, +please call your PCP or go to the emergency room. + +Followup Instructions: +Please call Dr. [**Last Name (STitle) **] office and make an appointment to see +him on or about [**12-8**]. She will also need a repeat CT scan on +that same day. His office number is [**Telephone/Fax (1) 1669**]. They can +also help schedule the CT Scan. + + + +",121,2155-10-29 13:03:00,2155-11-29 13:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,CELLULITIS," +[**age over 90 **] f with with copd on home 02, h/o cva, dm ii, diastolic chf, +mrsa +, admitted with foot ulcer, hospitalization complicated by +fall w/ sdh, fevers, & worsening mental status. + +# sdh: [**hospital **] hospital course was complicated by sdh which was +sustained s/p fall. initial ct showed 4mm hematoma, next ct on +[**11-5**] showed expansion to 8mm, repeats on [**11-6**] & [**11-7**] have been +stable. neurosurgery recommended supportive care only. held +anti-coagulation/anti-platelet agents. repeated cts showed no +changes. eeg no signs of seizure ativity. keppra given for +seizure prophlaxis but stoped as it was thought to be +contributing to ms changes. repeat ct scans stable and examined +by neurosurgery. patient was restarted on asa per nsg recs. +she was seen by neurosurgery prior to discharge and had plans to +see them in clinic in [**2-4**] weeks. at that time the patient will +need a repeat head ct. + +# altered mental status: per family pt has been ""unresponsive""/ +minimally responsive for two days, since her fall. at baseline, +pt is interactive & talkative, though demented. has been +minimally responsive voice & painful stimili for ~24hr. [**2155-11-8**] +am not responding to painful stimuli. suspect that some of ms +change is due to effect of sdh, though there is no shift/mass +effect. could be some infectious component, though no clear +source apart from her l foot ulcer, which appears to be +improving. no metabolic abnormalities to explain change. could +be related to hypothyroidism. treated for potential infections. +pt became more alert without any intervention. at the time of +discharge, the patient was answering questions with yes or no +answers and following basic commands. + +# hypotension: patient had episode of hypotension while in the +hospital. she was transfered to the icu briefly where she +recieved fluids and was briefly on dopamine. thought to be +related to hypovolemia / antihypertension medications. she was +rehydrated in the micu and her blood pressures improved. she +was slowly restarted on her home bp meds as her bp tolerated. + +#pneumonia: patient was noted to have episodes of tachypnea and +tachycardia. cxray revealed a infiltrate. suspicion for +aspiration pneumonia and patient was started on flagyl and +levoquin on [**2155-11-27**]. she will need to complete a 10 day course +(last day should be [**2155-12-6**]). + +#foot ulcer: mri w/o definitive evidence of osteo. she will be +treated with a 6 week total course of vancomycin for the +infection. wound swab postive for mrsa. course to end on +[**2155-12-10**]. dosing based on levels (goal vanco trough >15; +currently on q 36hr dosing). + +# copd: on home o2, 2l, w/ baseline 02 sats 90-95% per family. +she was continued on nebs and o2 as needed while hospitalized. + +# cad: patient was ruled out during hypotensive episode. cardiac +enzymes remained negative and her ekgs were without evidence of +acute events. she was continued on asa but plavix was held per +neurosurgery recs. + +# anemia: has anemia of chronic disease at baseline--confirmed +by iron studies this admission. hct has slowly dropped from ~37 +on admission to 24 and stabilized at 27. causes likely include +possible slow gib, repeated phlebotomy, and acute illness. no +gross hemorrhage, apart from sdh, which is stable. hemolysis +labs negative. she was noted to be guiac positive during this +admission which will need futher workup as an outpatient. she +did not require any tranfusions. + +# diastolic chf: ef 50-55%. jvp ~5. appears euvolemic on exam. + patients metoprolol was held after her transfer to the icu. +she was continued on her lisinopril without signs of volume +overload. her metoprolol was restarted on the day of discharge. + +# hyponatremia - patient was noted to be mildly hyponatermic at +times during admission. sodium responded to gentle iv hydration +with normal saline. + +# hypothyroid: she was continued on her home levothyroxine. + +# dm2: at home patient controlled with diet and glipizide. she +was covered with sliding scale while in house. sugars were well +controlled. because her sugars were well controlled her +glipizide was not restarted at the time of discharge. + +# fen: patient was started on tube feeds. she failed multiple +speech and swallow evaluations. after discussion with patients +family, a g/j tube was placed. + + + ","PRIMARY: [Diabetes with peripheral circulatory disorders, type II or unspecified type, not stated as uncontrolled] +SECONDARY: [Other and unspecified cerebral laceration and contusion, without mention of open intracranial wound, with no loss of consciousness; Cellulitis and abscess of foot, except toes; Unspecified osteomyelitis, ankle and foot; Pneumonitis due to inhalation of food or vomitus; Chronic diastolic heart failure; Atherosclerosis of native arteries of the extremities with ulceration; Anemia of other chronic disease; Congestive heart failure, unspecified; Ulcer of other part of foot; Diabetes with other specified manifestations, type II or unspecified type, not stated as uncontrolled; Other bone involvement in diseases classified elsewhere; Methicillin susceptible Staphylococcus aureus in conditions classified elsewhere and of unspecified site; Infection with microorganisms resistant to penicillins; Unspecified fall; Accidents occurring in residential institution; Esophageal reflux; Osteoporosis, unspecified; Dysthymic disorder; Coronary atherosclerosis of native coronary artery; Chronic airway obstruction, not elsewhere classified; Diarrhea; Epistaxis; Other iatrogenic hypotension; Other antihypertensive agents causing adverse effects in therapeutic use]" +19827,199336.0,15704,2106-06-11,15703,166475.0,2106-05-20,Discharge summary,"Admission Date: [**2106-5-13**] Discharge Date: [**2106-5-20**] + +Date of Birth: [**2038-4-1**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 2234**] +Chief Complaint: +Hypotension + +Major Surgical or Invasive Procedure: +Central Veinous line placement +PICC placement + +History of Present Illness: +This is a 68M t4 level paraplejia, CAD, CHF EF , severe sacral +debub, multiple UTIs, PE with IVC filter who is sent from rehab +with Hypotension. Of note, recently discharged from [**Hospital1 18**] after +and admission for code stroke [**4-21**]--[**4-27**] which at the end, it +was thought to be a seizure episode. Prior to that, admitted +[**2106-4-6**]- [**2106-4-15**] for fever and hypotension treated for UTI and +wound infection with Vanc/Zosyn compleatted on [**4-21**]. +. +Sent to the ED, after he was noted hypotensive today into the +60's.Per referal, he was noted with BO into the 60's that did +not repond to fluid boluses. Per report, his baseline BP +80-90's. He had also been currently treated with antibiotics for +a UTI. He completely his Vancomycin/Zosyn treatment course for +enterococi UTI and decub/ulcer swab infection on [**4-21**]. +. +In the ED, VS: He was hypotensive into the 60's, good mental +status. A IJ line was placed and levophed was started. Levophed +was also started. ID was curvesided and agreed with Vanc/Zosyn +for empiric coverage + +. +ROS: Denied fever, chills, SOB, cough, chest pain, abdominal +pain, blood in stools, weight gain or weight loss + + +Social History: +He moved here from [**Country 3594**] (after living in many different +countries) in the [**2068**]. He is retired from a job in the +maritime industry. Divorced 24 years ago. Three children. +Quit smoking [**2076**]. Quit drinking [**2080**]. No history of illicit +drug use or abuse. + + +Family History: +No stroke, aneurysm, no seizure, no AAA. + +Pertinent Results: +Admit labs: + +[**2106-5-13**] 01:25PM BLOOD WBC-9.4# RBC-3.52* Hgb-8.7* Hct-28.1* +MCV-80* MCH-24.8* MCHC-31.1 RDW-17.0* +[**2106-5-13**] 01:25PM BLOOD PT-26.6* PTT-38.4* INR(PT)-2.7* +[**2106-5-13**] 01:25PM BLOOD Glucose-101 UreaN-15 Creat-1.1 Na-139 +K-4.7 Cl-104 HCO3-24 AnGap-16 +[**2106-5-13**] 01:25PM BLOOD ALT-5 AST-10 LD(LDH)-124 CK(CPK)-50 +AlkPhos-89 TotBili-0.2 +[**2106-5-13**] 01:25PM BLOOD Albumin-2.8* Calcium-8.6 Phos-2.3* Mg-1.6 +[**2106-5-14**] 04:00AM BLOOD Cortsol-14.0 +================================================= +Discharge labs: + +[**2106-5-19**] 03:19AM BLOOD WBC-6.3 RBC-3.17* Hgb-7.7* Hct-25.5* +MCV-81* MCH-24.2* MCHC-30.1* RDW-17.6* Plt Ct-146* +[**2106-5-19**] 03:19AM BLOOD Plt Ct-146* +[**2106-5-19**] 03:19AM BLOOD PT-29.5* PTT-37.4* INR(PT)-3.0* +[**2106-5-19**] 03:19AM BLOOD Glucose-79 UreaN-5* Creat-0.5 Na-140 +K-3.9 Cl-109* HCO3-24 AnGap-11 +[**2106-5-18**] 05:50AM BLOOD ALT-6 AST-9 AlkPhos-78 Amylase-46 +TotBili-0.2 +[**2106-5-19**] 03:19AM BLOOD Mg-1.7 +Cholesterol: + +[**2106-5-17**] 05:40AM BLOOD Triglyc-79 HDL-18 CHOL/HD-3.1 LDLcalc-21 +[**2106-5-17**] 05:40AM BLOOD Cholest-55 +========================================================== +ECG:Sinus rhythm. Prior inferior myocardial infarction. Diffuse +non-specific +ST-T wave changes. Compared to the previous tracing of [**2106-4-22**] +there is +diffuse ST segment and T wave flattening. Otherwise, no +diagnostic interim +change. +========================================================== + +CHEST (PORTABLE AP); -77 BY DIFFERENT PHYSICIAN + +Reason: infiltrate? pneumothorax? + +[**Hospital 93**] MEDICAL CONDITION: +68 year old man with urosepsis, s/p hypoxia and coughing, +increased o2 requirement +REASON FOR THIS EXAMINATION: +infiltrate? pneumothorax? +AP CHEST 8:45 P.M. [**5-13**] + +HISTORY: Hypoxia and coughing. Possible pneumothorax. + +IMPRESSION: AP chest compared to [**4-21**] through [**5-13**]: + +Lungs are clear. Heart size normal. No pneumothorax or pleural +effusion. The patient has had median sternotomy. Tip of the +right jugular line projects over the upper SVC. No pneumothorax. +============================================================== +MR [**Name13 (STitle) 6452**] W & W/O CONTRAST [**2106-5-17**] 8:23 AM + +MR [**Name13 (STitle) 6452**] W & W/O CONTRAST + +Reason: Please evalaute L-spine/coccyx--patient with multiple +sacral +Contrast: MAGNEVIST + +[**Hospital 93**] MEDICAL CONDITION: +68 year old man with T4 paraplegia, multiple sacral decub +include probe to bone- admit with sepsis-unclear source +REASON FOR THIS EXAMINATION: +Please evalaute L-spine/coccyx--patient with multiple sacral +decubitus ulcers, sepsis unclear source--?osteomyelitis +CONTRAINDICATIONS for IV CONTRAST: None. + +INDICATION: T4 paraplegia with multiple sacral decubitus ulcers +probing to bone. Admitted with sepsis of unclear source. Please +evaluate for osteomyelitis. + +TECHNIQUE: Multiplanar T1- and T2-weighted images were obtained +through the lumbar spine without and with intravenous contrast. + +COMPARISON: MR lumbar spine images of [**2105-2-20**]. + +MR LUMBAR SPINE WITHOUT AND WITH CONTRAST: Sagittal images were +obtained through the lumbosacral spine; however, axial images go +through S1-S2. There is no evidence of lumbar spine fracture or +malalignment. At L2-L3 and L3-L4, there is no evidence of +significant canal stenosis or neural foraminal narrowing. At +L4-L5, there are degenerative endplate changes consistent with +type 2 [**Last Name (un) 13425**] changes. There is mild loss of disc height with +mild-to-moderate left and moderate right neural foraminal +narrowing without significant canal stenosis. + +At L5-S1, there are type 2 [**Last Name (un) 13425**] degenerative changes of the +endplates with mild loss of the vertebral body and disc space +height. A mild central disc bulge is again noted along with mild +bilateral facet hypertrophy causing moderate left and +mild-to-moderate right neural foraminal narrowing. + +There has been no change in the signal intensity within the +lumbosacral spine since the prior exam. There is no abnormal +enhancement. There is no evidence of osteomyelitis. There is +marked atrophy of the conus of the spinal cord as well as the +paraspinal musculature consistent with the patient's history of +paraplegia. + +IMPRESSION: +1. No evidence of osteomyelitis within the lumbar spine and +visualized portion of the sacrum. +2. Multilevel degenerative changes as described above without +high-grade spinal canal stenosis. +3. Atrophy of the conus of the spinal cord and paraspinal +muscles consistent with paraplegia +============================================================= + +Brief Hospital Course: +68M T4 paraplegia, CAD, systolic CHF, sacral decubitus ulcers, +multiple UTIs, PE with IVC filter on anticoagulation admitted +with hypotension. +. +# Hypotension/Septicemia: Pt (chronic nursing home pt) was +considered to have multiple possible sources of infection +including lines, urosepsis, and decubitus ulcers. Pt was +started on vancomycin for MRSA, meropenem for pseudomonas, +ciprofloxacin for double GNR coverage, and metronidazole for +anaerobic coverage. Of note, had been on levoquin and flagyl +for unclear reasons at [**Hospital 100**] Rehab for sometime before +admission to [**Hospital1 18**]. Aggressive fluid rescucitation and pressors +in ICU. Pt was taken off pressors two days after admission, and +remained afebrile throughout. PICC line removed, foley catheter +changed. Blood, urine, and midline cultures remained no growth +throughout but were of little value given antibiotic therapy +preceding cultures. Plastic surgery evaluated sacral decubs +and did not feel they were likely source of sepsis. MRI of +sacral decubs without evidence of sepsis. C. diff considered, no +samples sent in ICU and then on floor, no stool for sample. +Influenza negative. Appropriate adrenal response on [**Last Name (un) 104**] stim +testing. +Patient to receive two week course of vancomycin/meropenem given +septicemia without source. He should receive flagyl for one +week after completion of these given high risk for c. diff and +possible c. diff as cause of septicemia. Needs safety labs +including CBC, chem-10, lft's [**5-24**]. 7more days vanc/meropenm +and 14 days flagyl. +********Please note, after this course, patient should have +serial blood cultures, urine cultures and evaluation/wound +culture by plastic surgery as he has had multiple admissions for +septicemia of unclear etiology. He should not be treated +empirically with antibiotics unless these cultures are performed +or unless he is critically ill, precluding the ability to obtain +these cultures. It is strongly suspected that his decubitus +ulcers may be leading to these episodes, but almost chronic +institution of antibiotics without culture data precludes +definitive treatment. +Furthermore, patient has baseline low blood pressure from +chronic systolic heart failure and possible autonomic +dysregulation. On discharge, BP 80's to 100's on low dose +lisinopril and carvedilol +. +# Decubitus ulcer: Pt was noted to have extensive decubitus +ulcers, and plastics as well as wound care were consulted. +Wound care recs were followed; plastics did not feel further +imaging or tissue sampling was warranted. MRI was obtained and +did not demonstrate osteomyelitis. +. +Chronic Systolic Heart Failure: EF 25%. With aggressive +fluids/pressors, no pulmonary edema. Low dose lisinopril and +carvedilol re-started by [**5-18**]. BP's generally 80's to 100's. +. +Coronary Artery Disease: No specific ischemic changes on ECG. +Maintained on aspirin. Beta blocker and ace inhibitor added by +discharge. Statin discontinued as cholesterol very low (total +of 55). +. +# PE s/p IVC filter: Pt's warfarin was initially held given INR +3.5; anticoagulation dosing was per INR with goal between 2 and +3. On day of d/c, [**5-20**] INR of 2.9, plan 1mg coumadin today. +Should have INR check on [**5-21**] and then week of [**5-23**]. +. +# Depression: Continued citalopram +. +# h/o seizures: Continued Keppra +. +# h/o cholelitiasis/abdominal pain/GERD: Patient with +intermittent complaints of RUQ and epigastric abdominal pain, +also left sided chest.. PPI changed to [**Hospital1 **], tums and maalox +added. LFT's within normal limits on serial measurements. RUQ +U/S showed large stone in gallbladder which has been seen +previously, no evidence choleycystitis +Continued ursodiol throughout. If ongoing pain, patietn should +be evaluated by surgery once he has completed his antibioitic +course for consideration of choleycystectomy +. + + +Medications on Admission: +Ipratropium q8h +Levetiracetam 500 [**Hospital1 **] +levofloxacine 250 daily [**2106-5-5**] [**2106-5-19**] +Megace 400 mg once daily +Metronidazol 500 mg TID [**2106-5-5**] / [**2106-5-19**] -- apparently after +debridment. +Omeprazole 20 mg daily +Ondansetron 4 mg q8h +Oxycodone 5 mg TID +potassium 20 meq +Senna 1 tab +ursodiol 300 mg [**Hospital1 **] +warfarin [**5-12**] 0.5 mg INR [**2106-5-12**] 2.3 +albuterol 2 puff q6h +aspirin 81 daily +Baclofen 10 mg TID +Bisacodyl 10 mg once daily +Calcium carbonate 650 TID +Carvedilol 3.125 [**Hospital1 **] +Citalopram 30 mg qd +fluticasone/salmeterol Advair 250/50 +Gabapentin 300 [**Hospital1 **] +Insulin sliding scale +PRN +Tylenol 650 q4h +MAALOx +Prochlorperazine 25 mg q12 rectall + +Discharge Medications: +1. Levetiracetam 500 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +3. Citalopram 20 mg Tablet Sig: 1.5 Tablets PO DAILY (Daily). +4. Baclofen 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times a day). + +5. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +6. Carvedilol 3.125 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +7. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +8. Albuterol 90 mcg/Actuation Aerosol Sig: Two (2) Puff +Inhalation Q6H (every 6 hours). +9. Ipratropium Bromide 17 mcg/Actuation Aerosol Sig: Two (2) +Puff Inhalation QID (4 times a day). +10. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +11. Ursodiol 300 mg Capsule Sig: One (1) Capsule PO BID (2 times +a day). +12. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +13. Cyanocobalamin 500 mcg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +14. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO TID (3 times a day). +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +16. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +17. Oxycodone 5 mg Tablet Sig: One (1) Tablet PO Q6H (every 6 +hours) as needed. +18. Warfarin 1 mg Tablet Sig: One (1) Tablet PO once for 1 +doses: on [**5-20**]. +19. Warfarin 2 mg Tablet Sig: One (1) Tablet PO once a day: must +have INR check on [**5-21**] and [**5-23**] Goal INR is [**3-14**]. +20. Meropenem 500 mg Recon Soln Sig: Five Hundred (500) mg Recon +Soln Intravenous Q6H (every 6 hours) for 7 days. +21. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous Q 12H (Every 12 Hours) for 7 days. +22. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 14 days. +23. Simethicone 80 mg Tablet, Chewable Sig: One (1) Tablet, +Chewable PO TID (3 times a day) as needed for gas. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +1. Septicemia, NOS +2. Chronic Systolic Heart Failure +3. Coronary Artery Disease +4. Pulmonary Embolism +5. Paraplegia +6. Sacral Decubitus Ulcer +7. GERD +8. choledocholithiasis without obstruction +9. Anemia +10. Seizure history + +Discharge Condition: +Afebrile, stable, tolerating PO intake, systolic bp 80-100 + +Discharge Instructions: +Adhere to 2 gm sodium diet +Fluid Restriction:2 liters +. +All medications as prescribed. We have made a number of +changes. Please note patient to receive coumadin 1mg on [**2106-5-20**] +for INR of 2.9 and then to resume coumadin therapy on [**2106-5-20**]. +Should have INR checked on [**2106-5-21**] to guide further therapy (had +been getting 2mg daily but now on multiple antibiotics). Goal +INR is between 2 and 3. Usual dose will likely need to be +altered given concurrent vancomycin/meropenem/flagyl therapy. + +Patient's systolic blood pressure generally between 80 and 100. +Patient should receive lisinopril and carvedilol unless bp drops +below eighty given his heart failure. + +Once patient completes antibiotic course, should have blood +cultures sent and be seen by plastic surgery. He has had a +number of admissions for sepsis of unclear etiology. He should +not be treated with empiric antibiotics before having blood, +urine and wound cultures sent unless he is critically ill. + +Patient should have INR checked on [**5-21**] and then during week of +[**5-23**] to guide coumadin therapy. + +Patient should have full set of safety labs checked [**5-24**] +including CBC, Chem-10, alt, ast, total bilirubin. + +Patient has ongoing right upper quadrant/right sided chest pain. + It has been extesnively worked up. he does have gallstones but +no evidence of choleycystitis. If this is ongoing, he should be +evaluated by a surgeon once he has finished his antibiotic +course. +Follow up as below. + +Followup Instructions: +Patient should follow up with primary care doctor within two +weeks of discharge from [**Hospital **] Rehab. You will be followed by +doctors there in the meantime. + +You should follow up with plastic surgery here at [**Hospital3 **] +after completing your antibiotic course. + +You also have the previously scheduled appointments: +Neurology: Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 7598**], MD Phone:[**Telephone/Fax (1) 5434**] +Date/Time:[**2106-7-16**] 9:30 + +Cardiology: +Provider: [**First Name11 (Name Pattern1) **] [**Initial (NamePattern1) **] [**Last Name (NamePattern4) **], [**First Name3 (LF) 3947**]. Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2106-11-3**] 9:40 +Provider: [**Name10 (NameIs) **] Phone:[**Telephone/Fax (1) 128**] Date/Time:[**2106-11-3**] +11:00 + + + +",22,2106-05-13 16:51:00,2106-05-20 17:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,HYPOTENSION," +68m t4 paraplegia, cad, systolic chf, sacral decubitus ulcers, +multiple utis, pe with ivc filter on anticoagulation admitted +with hypotension. +. +# hypotension/septicemia: pt (chronic nursing home pt) was +considered to have multiple possible sources of infection +including lines, urosepsis, and decubitus ulcers. pt was +started on vancomycin for mrsa, meropenem for pseudomonas, +ciprofloxacin for double gnr coverage, and metronidazole for +anaerobic coverage. of note, had been on levoquin and flagyl +for unclear reasons at [**hospital 100**] rehab for sometime before +admission to [**hospital1 18**]. aggressive fluid rescucitation and pressors +in icu. pt was taken off pressors two days after admission, and +remained afebrile throughout. picc line removed, foley catheter +changed. blood, urine, and midline cultures remained no growth +throughout but were of little value given antibiotic therapy +preceding cultures. plastic surgery evaluated sacral decubs +and did not feel they were likely source of sepsis. mri of +sacral decubs without evidence of sepsis. c. diff considered, no +samples sent in icu and then on floor, no stool for sample. +influenza negative. appropriate adrenal response on [**last name (un) 104**] stim +testing. +patient to receive two week course of vancomycin/meropenem given +septicemia without source. he should receive flagyl for one +week after completion of these given high risk for c. diff and +possible c. diff as cause of septicemia. needs safety labs +including cbc, chem-10, lfts [**5-24**]. 7more days vanc/meropenm +and 14 days flagyl. +********please note, after this course, patient should have +serial blood cultures, urine cultures and evaluation/wound +culture by plastic surgery as he has had multiple admissions for +septicemia of unclear etiology. he should not be treated +empirically with antibiotics unless these cultures are performed +or unless he is critically ill, precluding the ability to obtain +these cultures. it is strongly suspected that his decubitus +ulcers may be leading to these episodes, but almost chronic +institution of antibiotics without culture data precludes +definitive treatment. +furthermore, patient has baseline low blood pressure from +chronic systolic heart failure and possible autonomic +dysregulation. on discharge, bp 80s to 100s on low dose +lisinopril and carvedilol +. +# decubitus ulcer: pt was noted to have extensive decubitus +ulcers, and plastics as well as wound care were consulted. +wound care recs were followed; plastics did not feel further +imaging or tissue sampling was warranted. mri was obtained and +did not demonstrate osteomyelitis. +. +chronic systolic heart failure: ef 25%. with aggressive +fluids/pressors, no pulmonary edema. low dose lisinopril and +carvedilol re-started by [**5-18**]. bps generally 80s to 100s. +. +coronary artery disease: no specific ischemic changes on ecg. +maintained on aspirin. beta blocker and ace inhibitor added by +discharge. statin discontinued as cholesterol very low (total +of 55). +. +# pe s/p ivc filter: pts warfarin was initially held given inr +3.5; anticoagulation dosing was per inr with goal between 2 and +3. on day of d/c, [**5-20**] inr of 2.9, plan 1mg coumadin today. +should have inr check on [**5-21**] and then week of [**5-23**]. +. +# depression: continued citalopram +. +# h/o seizures: continued keppra +. +# h/o cholelitiasis/abdominal pain/gerd: patient with +intermittent complaints of ruq and epigastric abdominal pain, +also left sided chest.. ppi changed to [**hospital1 **], tums and maalox +added. lfts within normal limits on serial measurements. ruq +u/s showed large stone in gallbladder which has been seen +previously, no evidence choleycystitis +continued ursodiol throughout. if ongoing pain, patietn should +be evaluated by surgery once he has completed his antibioitic +course for consideration of choleycystectomy +. + + + ","PRIMARY: [Unspecified septicemia] +SECONDARY: [Septic shock; Acute systolic heart failure; Paraplegia; Pressure ulcer, buttock; Pressure ulcer, lower back; Pressure ulcer, hip; Severe sepsis; Chronic airway obstruction, not elsewhere classified; Congestive heart failure, unspecified; Esophageal reflux; Personal history of venous thrombosis and embolism]" +19827,199336.0,15704,2106-06-11,15702,178197.0,2106-04-15,Discharge summary,"Admission Date: [**2106-4-6**] Discharge Date: [**2106-4-15**] + +Date of Birth: [**2038-4-1**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Fever, hypotension + +Major Surgical or Invasive Procedure: +Bedside debridement of ulcerations by plastic surgery team + + +History of Present Illness: +68M with h/o t4 paraplegia x 2yrs, felt [**3-13**] ""inflammatory spinal +disease"", with a chronic indwelling foley, sacral decubitus +ulcers, presents to [**Hospital1 18**] from rehab after RN noted 1d of fever +(tmax 101.8). [**Name8 (MD) **] RN caring for pt at rehab, pt noted some mild +abdominal discomfort (chronic), but otherwise denied any recent +symptoms of cough, n/v, constipation, rash. Pt has been having +chronic diarrhea (x3/day, x2-3/night) for past 1yr, etiology +unclear. [**Name2 (NI) 227**] persistent fevers x24hrs, pt was brought to +[**Hospital1 18**] ED. [**Name8 (MD) **] RN BP prior to leaving rehab was 100/72. +. +Per pt, he notes chronic abdominal pain, ""always there"", +diffuse, sharp, sometimes awakening him from sleep, no relation +to food or BMs. somewhat worse over the preceding 4 months, but +actually improving over the past few days. At present, he +states his pain has completely resolved. ROS otherwise +significant for +orthopnea, pt also notes nonproductive cough x +3 weeks, no flu sx (body aches, congestion, sore throat). Pt +denies flut shot or pneumovax. +sick contacts (lives in [**Hospital 100**] +Rehab). +. +Upon arrival in ED VS=100.4 100 87/51 12 95%RA. UA was c/w +UTI, pt was started on vanco and zosyn, UCx and BCx sent. +sacral ulcers felt to be stage 4, no evidence of superinfection. + BP initially responded to 3L IVF (99/53), however after 3rd +litre, BP down to 85/40, pt therefore received RIJ TLC, and +possibly an additional 1L IVF bolus, afterwhich BP improved to +115/70. Pt was asymptomatic, mentating throughout without +specific complaints. +. +Pt also noted moderate abdominal tenderness. CT ABD done which +showed no acute processes. CXR unremarkable, EKG unremarkable +(old Q in III, ?mild ST changes V1). +. +Pt admitted to ICU for further monitoring given hypotension. +. + +Past Medical History: +1. Inflammatory disease of the spinal cord of uncertain +etiology. MRA [**10-16**] negative for vascular malformation. Initial +CSF analysis showed elevated protein (82) without oligoclonal +bands. NMO blood titer negative, RPR negative, Lyme serology +negative, [**Doctor First Name **] negative, Ro and La negative, ACE level normal, +neuromyelitis IgG negative, ESR 70, CRP 66.8. Ultimately +treated with broad spectrum antibiotics, corticosteroids (two +weeks of Solu-Medrol followed by a prednisone taper), and 5 days +of mannitol without improvement. He is followed by neurology +for a dense paraplegia (T4) with neuropathic pain, restrictive +shoulder arthropathy, and a neurogenic bladder requiring a +chronic indwelling foley. +2. Chronic sacral decubitus ulcer, previously treated with a VAC +dressing +3. Multiple UTI (including Pseudomonas) +4. Pulmonary embolus [**11-15**] s/p IVC filter placement +5. Asthma +6. Two-vessel coronary artery disease s/p CABG 4-5 years ago +7. Systolic CHF (EF 25-30% on [**2-15**] TTE) +8. Repaired liver laceration +9. Chronic back pain +10. Vitiligo +11. Feeding tube +12. Depression +13. MRSA from sacral swab and sputum +14. Prior transient episodes of leg paralysis +15. Right frontal lobe brain lesion biopsied [**11-15**] and c/w +gliosis; resolved on repeat imaging +16. Abnormal visual evoked potentials + +Social History: +He moved here from [**Country 3594**] (after living in many different +countries) in the [**2068**]. He is retired from a job in the +maritime industry. Divorced 24 years ago. Three children. +Quit smoking [**2076**]. Quit drinking [**2080**]. No history of illicit +drug use or abuse. + + +Family History: +No stroke, aneurysm, no seizure, no AAA. + +Physical Exam: +VS: 96.6 85 105/66 15 100%2L +Gen: Well appearing male in NAD lying in bed. +HEENT: JVD <6-8cm, MMM, lips slightly pale. +Chest: CTA bilaterally, no w/r/r. +CV: RRR, physiologic splitting S2, no r/g. 3/6 SEM @ LSB. +Abd: Soft, nontender to deep palpation in all four quadrants, +distended, tympanic (?gas), negative murphys sign, well-healed +midline g-tube scar. +Extremities: Warm, well perfused, no C/C. [**2-10**]+ edema bilaterally +to knees. +Skin: Vitiligo on hands. Large round 6x4 cm diameter pressure +decubitus ulcer on sacrum and 4x3cm decub ulcer on left ischial +tuberosity. Appears clean with granulation tissue in center, no +s/sx of infection. no purulent drainage. +Neuro: CN grossly intact. A&O x 3, pleasantly conversant. + + +Pertinent Results: +[**2106-4-5**] 11:50PM BLOOD WBC-9.08 RBC-4.37* Hgb-11.2* Hct-34.9* +MCV-80* MCH-25.6* MCHC-32.0 RDW-15.1 +[**2106-4-8**] 04:47AM BLOOD WBC-6.7 RBC-3.49* Hgb-8.9* Hct-28.5* +MCV-82 MCH-25.6* MCHC-31.4 RDW-14.9 +[**2106-4-5**] 11:50PM BLOOD Glucose-125* UreaN-11 Creat-0.5 Na-137 +K-4.0 Cl-101 HCO3-27 AnGap-13 +[**2106-4-8**] 04:47AM BLOOD Glucose-109* UreaN-5* Creat-0.4* Na-139 +K-3.7 Cl-110* HCO3-23 AnGap-10 +[**2106-4-6**] 10:27PM BLOOD CK-MB-5 cTropnT-0.08* +[**2106-4-6**] 08:11AM BLOOD cTropnT-0.08* +[**2106-4-5**] 11:50PM BLOOD CK-MB-NotDone cTropnT-0.09* +[**2106-4-8**] 04:47AM BLOOD Calcium-8.2* Phos-3.0 Mg-2.0 +[**2106-4-6**] 12:05PM BLOOD Cortsol-15.3 +[**2106-4-6**] 12:05PM BLOOD CRP-122.0* +[**2106-4-6**] 01:45PM BLOOD Lactate-1.4 +[**2106-4-6**] 12:00PM BLOOD Lactate-0.7 +[**2106-4-6**] 12:02AM BLOOD Lactate-1.7 + +CT ABD/Pelv [**2106-4-6**]: +1. Severe sacral and right ischial tuberosity decubitus ulcers. +2. No acute intra-abdominal inflammatory process. +3. Cholelithiasis. + +CXR [**4-6**] Bedside frontal chest radiograph is compared to +[**2106-1-2**] and demonstrate clear lungs, normal pulmonary +vasculature, and no evidence for pleural effusions. The heart +and mediastinal contours, remarkable for tortuous aorta, are +stable. This patient is status post median sternotomy. + +IMPRESSION: No acute cardiopulmonary process. + +EKGs: NSR, essentially unchanged from prior tracings + +WBC scan; + +IMPRESSION: 1. Unchanged appearance of residual sacrum with +adjacent posterior +focal radiotracer uptake, again apparently within adjacent soft +tissues. +However, given the proximity of the uptake, bony involvement +with infection +cannot be excluded. +2. Similar sclerotic appearance of right lower ischium and +adjacent soft +tissue thickening. Although the CT appearance suggests chronic +osteomyelitis, +immediately adjacent radiotracer activity has resolved and the +bony abnormality +appears unchanged. +3. New cellulitis along the right lower buttock, at the +interface with the +thigh and inferior to the prior site of infection. +4. More extensive radiotracer uptake in the left lower buttock, +with fat +stranding on CT suggesting cellulitis. Although the soft tissue +abnormality +extends to the ischial tuberosity, there is no CT evidence of +bone destruction +or abnormal bony radiotracer uptake in this area. + +[**2106-4-6**] 6:38 pm SWAB Source: left ischial tuberosity. + + **FINAL REPORT [**2106-4-10**]** + + GRAM STAIN (Final [**2106-4-6**]): + 1+ (<1 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + NO MICROORGANISMS SEEN. + + WOUND CULTURE (Final [**2106-4-10**]): + Due to mixed bacterial types ( >= 3 colony types) an +abbreviated + workup is performed appropriate to the isolates recovered +from the + site (including a screen for Pseudomonas aeruginosa, +Staphylococcus + aureus and beta streptococcus). + Susceptibility will be performed on P. aeruginosa and S. +aureus if + sparse growth or greater. + STAPH AUREUS COAG +. SPARSE GROWTH. + Oxacillin RESISTANT Staphylococci MUST be reported as +also + RESISTANT to other penicillins, cephalosporins, +carbacephems, + carbapenems, and beta-lactamase inhibitor combinations. + + Rifampin should not be used alone for therapy. + Please contact the Microbiology Laboratory ([**8-/2404**]) +immediately if + sensitivity to clindamycin is required on this +patient's isolate. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + STAPH AUREUS COAG + + | +ERYTHROMYCIN---------- =>8 R +GENTAMICIN------------ <=0.5 S +LEVOFLOXACIN---------- =>8 R +OXACILLIN------------- =>4 R +PENICILLIN------------ =>0.5 R +RIFAMPIN-------------- <=0.5 S +TETRACYCLINE---------- <=1 S +TRIMETHOPRIM/SULFA---- <=0.5 S +VANCOMYCIN------------ <=1 S + + ANAEROBIC CULTURE (Final [**2106-4-10**]): NO ANAEROBES ISOLATED. + + + + + + +[**2106-4-6**] 6:38 pm SWAB Source: sacral decubitus ulcer. + + **FINAL REPORT [**2106-4-10**]** + + GRAM STAIN (Final [**2106-4-6**]): + 1+ (<1 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + NO MICROORGANISMS SEEN. + + WOUND CULTURE (Final [**2106-4-10**]): + ESCHERICHIA COLI. RARE GROWTH. + PSEUDOMONAS AERUGINOSA. RARE GROWTH. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ESCHERICHIA COLI + | PSEUDOMONAS AERUGINOSA + | | +AMPICILLIN------------ <=2 S +AMPICILLIN/SULBACTAM-- <=2 S +CEFAZOLIN------------- <=4 S +CEFEPIME-------------- <=1 S <=1 S +CEFTAZIDIME----------- <=1 S 4 S +CEFTRIAXONE----------- <=1 S +CEFUROXIME------------ 4 S +CIPROFLOXACIN--------- =>4 R <=0.25 S +GENTAMICIN------------ <=1 S <=1 S +MEROPENEM-------------<=0.25 S <=0.25 S +PIPERACILLIN---------- <=4 S 8 S +PIPERACILLIN/TAZO----- <=4 S 8 S +TOBRAMYCIN------------ <=1 S <=1 S +TRIMETHOPRIM/SULFA---- <=1 S + + ANAEROBIC CULTURE (Final [**2106-4-10**]): NO ANAEROBES ISOLATED. + + + +Brief Hospital Course: +A/P: 67M h/o T4 paraplegia, recurrent UTIs [**3-13**] indwelling foley, +multiple stage 4 decubs was admitted to ICU initially with fever +to 101.8, transient hypotension that resolved with 3-4L IVF but +continued on sepsis protocol. +. +# FEVER - Felt due to UTI and or osteomyelitis. Cx. all neg, +but swab suggested colonization with mrsa; also seen on swab, +pseudomonas and enterococcus. Emperically treated with +vancomycin and zosyn given this information and prior culture +data that was reviewed here. Tagged wbc scan as above. Plastic +surgery consult evaluated wounds and felt that pt. did not have +evidence of osteomyelitis. Plan two weeks of abx for empiric +treatment for complicated UTI. Foley replaced. Follow up with +[**Month/Day (2) **] arranged for evaluation for suprapubic catheter. Follow +up with plastic surgery also arranged. +. +# HYPOTENSION - resolved with IVF and treatment of infection as +above. + +# H/O PE - s/p IVC filter, INR elevated, so warfarin held, then +given 5 po vitamin K given sustained inr over 4.0. INR came +down to 1.8 with this, so warfarin resumed. + +Otherwise, home medication regimen continued in hospital for +other chronic medical issues as outlined in pmhx. and in +medication list below. + +Medications on Admission: +vitamin c 500mg po qdaily +aspirin 81mg po qdaily +baclofen 5mg po tid +calcium carbonate 650mg po bid +citalopram 40mg po qdaily +pepcid 20mg po qdaily +advair 250/50 IH [**Hospital1 **] +gabapentin 400mg po bid +simethicone 80mg po tid +simvastatin 40mg po qdaily +tramadol 25mg po tid +ursodiol 300mg po qdaily +warfarin 3mg po qdaily +prostat 30ml oral [**Hospital1 **] (liquid protein supplement) +. + + +Discharge Medications: +1. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous Q 12H (Every 12 Hours) for 7 days. gram +2. Piperacillin-Tazobactam-Dextrs 4.5 gram/100 mL Piggyback Sig: +One (1) Intravenous Q8H (every 8 hours) for 7 days. +3. Sodium Hypochlorite 0.25 % Solution Sig: One (1) Appl +Miscellaneous ASDIR (AS DIRECTED) for 1 days: apply to ischial +wounds only, for one day ([**4-16**]) in [**Hospital1 **] wet to dry dsg changes. +4. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +5. Baclofen 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times a day). + +6. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO BID (2 times a day). +7. Citalopram 20 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +8. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) inhalation Inhalation [**Hospital1 **] (2 times a day). +9. Gabapentin 400 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +10. Simethicone 80 mg Tablet, Chewable Sig: One (1) Tablet, +Chewable PO TID (3 times a day) as needed. +11. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +12. Tramadol 50 mg Tablet Sig: 0.5 Tablet PO TID (3 times a +day). +13. Ursodiol 300 mg Capsule Sig: One (1) Capsule PO QDAILY (). +14. Trazodone 50 mg Tablet Sig: 0.5 Tablet PO HS (at bedtime) as +needed. +15. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed. +16. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours) as needed. +17. Aluminum-Magnesium Hydroxide 225-200 mg/5 mL Suspension Sig: +15-30 MLs PO QID (4 times a day) as needed. +18. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +19. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: [**2-10**] Tablet, +Rapid Dissolves PO Q8H (every 8 hours) as needed. +20. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day. +Tablet(s) + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +UTI with sepsis +Chronic sacral and ischial decubitus ulcerations +Chronic, systolic, heart failure +Hx. PE with SVC filter, on warfarin + + +Discharge Condition: +Stable + + +Discharge Instructions: +Return to the [**Hospital1 18**] Emergency Department for: + +Fever +Hypotension + +Followup Instructions: +Provider: [**Name10 (NameIs) **] SURGERY CLINIC Phone:[**Telephone/Fax (1) 4652**] +Date/Time:[**2106-4-23**] 1:30 + +For evaluation for suprapubic catheter placment: + +Provider: [**Name10 (NameIs) **] UNIT Phone:[**Telephone/Fax (1) 164**] Date/Time:[**2106-4-28**] +9:30 + + + +",57,2106-04-06 07:05:00,2106-04-15 18:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,FEVER," +a/p: 67m h/o t4 paraplegia, recurrent utis [**3-13**] indwelling foley, +multiple stage 4 decubs was admitted to icu initially with fever +to 101.8, transient hypotension that resolved with 3-4l ivf but +continued on sepsis protocol. +. +# fever - felt due to uti and or osteomyelitis. cx. all neg, +but swab suggested colonization with mrsa; also seen on swab, +pseudomonas and enterococcus. emperically treated with +vancomycin and zosyn given this information and prior culture +data that was reviewed here. tagged wbc scan as above. plastic +surgery consult evaluated wounds and felt that pt. did not have +evidence of osteomyelitis. plan two weeks of abx for empiric +treatment for complicated uti. foley replaced. follow up with +[**month/day (2) **] arranged for evaluation for suprapubic catheter. follow +up with plastic surgery also arranged. +. +# hypotension - resolved with ivf and treatment of infection as +above. + +# h/o pe - s/p ivc filter, inr elevated, so warfarin held, then +given 5 po vitamin k given sustained inr over 4.0. inr came +down to 1.8 with this, so warfarin resumed. + +otherwise, home medication regimen continued in hospital for +other chronic medical issues as outlined in pmhx. and in +medication list below. + + ","PRIMARY: [Infection and inflammatory reaction due to indwelling urinary catheter] +SECONDARY: [Unspecified septicemia; Sepsis; Paraplegia; Pressure ulcer, lower back; Pressure ulcer, hip; Chronic systolic heart failure; Urinary tract infection, site not specified; Aortocoronary bypass status; Congestive heart failure, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +19827,166475.0,15703,2106-05-20,15702,178197.0,2106-04-15,Discharge summary,"Admission Date: [**2106-4-6**] Discharge Date: [**2106-4-15**] + +Date of Birth: [**2038-4-1**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1990**] +Chief Complaint: +Fever, hypotension + +Major Surgical or Invasive Procedure: +Bedside debridement of ulcerations by plastic surgery team + + +History of Present Illness: +68M with h/o t4 paraplegia x 2yrs, felt [**3-13**] ""inflammatory spinal +disease"", with a chronic indwelling foley, sacral decubitus +ulcers, presents to [**Hospital1 18**] from rehab after RN noted 1d of fever +(tmax 101.8). [**Name8 (MD) **] RN caring for pt at rehab, pt noted some mild +abdominal discomfort (chronic), but otherwise denied any recent +symptoms of cough, n/v, constipation, rash. Pt has been having +chronic diarrhea (x3/day, x2-3/night) for past 1yr, etiology +unclear. [**Name2 (NI) 227**] persistent fevers x24hrs, pt was brought to +[**Hospital1 18**] ED. [**Name8 (MD) **] RN BP prior to leaving rehab was 100/72. +. +Per pt, he notes chronic abdominal pain, ""always there"", +diffuse, sharp, sometimes awakening him from sleep, no relation +to food or BMs. somewhat worse over the preceding 4 months, but +actually improving over the past few days. At present, he +states his pain has completely resolved. ROS otherwise +significant for +orthopnea, pt also notes nonproductive cough x +3 weeks, no flu sx (body aches, congestion, sore throat). Pt +denies flut shot or pneumovax. +sick contacts (lives in [**Hospital 100**] +Rehab). +. +Upon arrival in ED VS=100.4 100 87/51 12 95%RA. UA was c/w +UTI, pt was started on vanco and zosyn, UCx and BCx sent. +sacral ulcers felt to be stage 4, no evidence of superinfection. + BP initially responded to 3L IVF (99/53), however after 3rd +litre, BP down to 85/40, pt therefore received RIJ TLC, and +possibly an additional 1L IVF bolus, afterwhich BP improved to +115/70. Pt was asymptomatic, mentating throughout without +specific complaints. +. +Pt also noted moderate abdominal tenderness. CT ABD done which +showed no acute processes. CXR unremarkable, EKG unremarkable +(old Q in III, ?mild ST changes V1). +. +Pt admitted to ICU for further monitoring given hypotension. +. + +Past Medical History: +1. Inflammatory disease of the spinal cord of uncertain +etiology. MRA [**10-16**] negative for vascular malformation. Initial +CSF analysis showed elevated protein (82) without oligoclonal +bands. NMO blood titer negative, RPR negative, Lyme serology +negative, [**Doctor First Name **] negative, Ro and La negative, ACE level normal, +neuromyelitis IgG negative, ESR 70, CRP 66.8. Ultimately +treated with broad spectrum antibiotics, corticosteroids (two +weeks of Solu-Medrol followed by a prednisone taper), and 5 days +of mannitol without improvement. He is followed by neurology +for a dense paraplegia (T4) with neuropathic pain, restrictive +shoulder arthropathy, and a neurogenic bladder requiring a +chronic indwelling foley. +2. Chronic sacral decubitus ulcer, previously treated with a VAC +dressing +3. Multiple UTI (including Pseudomonas) +4. Pulmonary embolus [**11-15**] s/p IVC filter placement +5. Asthma +6. Two-vessel coronary artery disease s/p CABG 4-5 years ago +7. Systolic CHF (EF 25-30% on [**2-15**] TTE) +8. Repaired liver laceration +9. Chronic back pain +10. Vitiligo +11. Feeding tube +12. Depression +13. MRSA from sacral swab and sputum +14. Prior transient episodes of leg paralysis +15. Right frontal lobe brain lesion biopsied [**11-15**] and c/w +gliosis; resolved on repeat imaging +16. Abnormal visual evoked potentials + +Social History: +He moved here from [**Country 3594**] (after living in many different +countries) in the [**2068**]. He is retired from a job in the +maritime industry. Divorced 24 years ago. Three children. +Quit smoking [**2076**]. Quit drinking [**2080**]. No history of illicit +drug use or abuse. + + +Family History: +No stroke, aneurysm, no seizure, no AAA. + +Physical Exam: +VS: 96.6 85 105/66 15 100%2L +Gen: Well appearing male in NAD lying in bed. +HEENT: JVD <6-8cm, MMM, lips slightly pale. +Chest: CTA bilaterally, no w/r/r. +CV: RRR, physiologic splitting S2, no r/g. 3/6 SEM @ LSB. +Abd: Soft, nontender to deep palpation in all four quadrants, +distended, tympanic (?gas), negative murphys sign, well-healed +midline g-tube scar. +Extremities: Warm, well perfused, no C/C. [**2-10**]+ edema bilaterally +to knees. +Skin: Vitiligo on hands. Large round 6x4 cm diameter pressure +decubitus ulcer on sacrum and 4x3cm decub ulcer on left ischial +tuberosity. Appears clean with granulation tissue in center, no +s/sx of infection. no purulent drainage. +Neuro: CN grossly intact. A&O x 3, pleasantly conversant. + + +Pertinent Results: +[**2106-4-5**] 11:50PM BLOOD WBC-9.08 RBC-4.37* Hgb-11.2* Hct-34.9* +MCV-80* MCH-25.6* MCHC-32.0 RDW-15.1 +[**2106-4-8**] 04:47AM BLOOD WBC-6.7 RBC-3.49* Hgb-8.9* Hct-28.5* +MCV-82 MCH-25.6* MCHC-31.4 RDW-14.9 +[**2106-4-5**] 11:50PM BLOOD Glucose-125* UreaN-11 Creat-0.5 Na-137 +K-4.0 Cl-101 HCO3-27 AnGap-13 +[**2106-4-8**] 04:47AM BLOOD Glucose-109* UreaN-5* Creat-0.4* Na-139 +K-3.7 Cl-110* HCO3-23 AnGap-10 +[**2106-4-6**] 10:27PM BLOOD CK-MB-5 cTropnT-0.08* +[**2106-4-6**] 08:11AM BLOOD cTropnT-0.08* +[**2106-4-5**] 11:50PM BLOOD CK-MB-NotDone cTropnT-0.09* +[**2106-4-8**] 04:47AM BLOOD Calcium-8.2* Phos-3.0 Mg-2.0 +[**2106-4-6**] 12:05PM BLOOD Cortsol-15.3 +[**2106-4-6**] 12:05PM BLOOD CRP-122.0* +[**2106-4-6**] 01:45PM BLOOD Lactate-1.4 +[**2106-4-6**] 12:00PM BLOOD Lactate-0.7 +[**2106-4-6**] 12:02AM BLOOD Lactate-1.7 + +CT ABD/Pelv [**2106-4-6**]: +1. Severe sacral and right ischial tuberosity decubitus ulcers. +2. No acute intra-abdominal inflammatory process. +3. Cholelithiasis. + +CXR [**4-6**] Bedside frontal chest radiograph is compared to +[**2106-1-2**] and demonstrate clear lungs, normal pulmonary +vasculature, and no evidence for pleural effusions. The heart +and mediastinal contours, remarkable for tortuous aorta, are +stable. This patient is status post median sternotomy. + +IMPRESSION: No acute cardiopulmonary process. + +EKGs: NSR, essentially unchanged from prior tracings + +WBC scan; + +IMPRESSION: 1. Unchanged appearance of residual sacrum with +adjacent posterior +focal radiotracer uptake, again apparently within adjacent soft +tissues. +However, given the proximity of the uptake, bony involvement +with infection +cannot be excluded. +2. Similar sclerotic appearance of right lower ischium and +adjacent soft +tissue thickening. Although the CT appearance suggests chronic +osteomyelitis, +immediately adjacent radiotracer activity has resolved and the +bony abnormality +appears unchanged. +3. New cellulitis along the right lower buttock, at the +interface with the +thigh and inferior to the prior site of infection. +4. More extensive radiotracer uptake in the left lower buttock, +with fat +stranding on CT suggesting cellulitis. Although the soft tissue +abnormality +extends to the ischial tuberosity, there is no CT evidence of +bone destruction +or abnormal bony radiotracer uptake in this area. + +[**2106-4-6**] 6:38 pm SWAB Source: left ischial tuberosity. + + **FINAL REPORT [**2106-4-10**]** + + GRAM STAIN (Final [**2106-4-6**]): + 1+ (<1 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + NO MICROORGANISMS SEEN. + + WOUND CULTURE (Final [**2106-4-10**]): + Due to mixed bacterial types ( >= 3 colony types) an +abbreviated + workup is performed appropriate to the isolates recovered +from the + site (including a screen for Pseudomonas aeruginosa, +Staphylococcus + aureus and beta streptococcus). + Susceptibility will be performed on P. aeruginosa and S. +aureus if + sparse growth or greater. + STAPH AUREUS COAG +. SPARSE GROWTH. + Oxacillin RESISTANT Staphylococci MUST be reported as +also + RESISTANT to other penicillins, cephalosporins, +carbacephems, + carbapenems, and beta-lactamase inhibitor combinations. + + Rifampin should not be used alone for therapy. + Please contact the Microbiology Laboratory ([**8-/2404**]) +immediately if + sensitivity to clindamycin is required on this +patient's isolate. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + STAPH AUREUS COAG + + | +ERYTHROMYCIN---------- =>8 R +GENTAMICIN------------ <=0.5 S +LEVOFLOXACIN---------- =>8 R +OXACILLIN------------- =>4 R +PENICILLIN------------ =>0.5 R +RIFAMPIN-------------- <=0.5 S +TETRACYCLINE---------- <=1 S +TRIMETHOPRIM/SULFA---- <=0.5 S +VANCOMYCIN------------ <=1 S + + ANAEROBIC CULTURE (Final [**2106-4-10**]): NO ANAEROBES ISOLATED. + + + + + + +[**2106-4-6**] 6:38 pm SWAB Source: sacral decubitus ulcer. + + **FINAL REPORT [**2106-4-10**]** + + GRAM STAIN (Final [**2106-4-6**]): + 1+ (<1 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + NO MICROORGANISMS SEEN. + + WOUND CULTURE (Final [**2106-4-10**]): + ESCHERICHIA COLI. RARE GROWTH. + PSEUDOMONAS AERUGINOSA. RARE GROWTH. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ESCHERICHIA COLI + | PSEUDOMONAS AERUGINOSA + | | +AMPICILLIN------------ <=2 S +AMPICILLIN/SULBACTAM-- <=2 S +CEFAZOLIN------------- <=4 S +CEFEPIME-------------- <=1 S <=1 S +CEFTAZIDIME----------- <=1 S 4 S +CEFTRIAXONE----------- <=1 S +CEFUROXIME------------ 4 S +CIPROFLOXACIN--------- =>4 R <=0.25 S +GENTAMICIN------------ <=1 S <=1 S +MEROPENEM-------------<=0.25 S <=0.25 S +PIPERACILLIN---------- <=4 S 8 S +PIPERACILLIN/TAZO----- <=4 S 8 S +TOBRAMYCIN------------ <=1 S <=1 S +TRIMETHOPRIM/SULFA---- <=1 S + + ANAEROBIC CULTURE (Final [**2106-4-10**]): NO ANAEROBES ISOLATED. + + + +Brief Hospital Course: +A/P: 67M h/o T4 paraplegia, recurrent UTIs [**3-13**] indwelling foley, +multiple stage 4 decubs was admitted to ICU initially with fever +to 101.8, transient hypotension that resolved with 3-4L IVF but +continued on sepsis protocol. +. +# FEVER - Felt due to UTI and or osteomyelitis. Cx. all neg, +but swab suggested colonization with mrsa; also seen on swab, +pseudomonas and enterococcus. Emperically treated with +vancomycin and zosyn given this information and prior culture +data that was reviewed here. Tagged wbc scan as above. Plastic +surgery consult evaluated wounds and felt that pt. did not have +evidence of osteomyelitis. Plan two weeks of abx for empiric +treatment for complicated UTI. Foley replaced. Follow up with +[**Month/Day (2) **] arranged for evaluation for suprapubic catheter. Follow +up with plastic surgery also arranged. +. +# HYPOTENSION - resolved with IVF and treatment of infection as +above. + +# H/O PE - s/p IVC filter, INR elevated, so warfarin held, then +given 5 po vitamin K given sustained inr over 4.0. INR came +down to 1.8 with this, so warfarin resumed. + +Otherwise, home medication regimen continued in hospital for +other chronic medical issues as outlined in pmhx. and in +medication list below. + +Medications on Admission: +vitamin c 500mg po qdaily +aspirin 81mg po qdaily +baclofen 5mg po tid +calcium carbonate 650mg po bid +citalopram 40mg po qdaily +pepcid 20mg po qdaily +advair 250/50 IH [**Hospital1 **] +gabapentin 400mg po bid +simethicone 80mg po tid +simvastatin 40mg po qdaily +tramadol 25mg po tid +ursodiol 300mg po qdaily +warfarin 3mg po qdaily +prostat 30ml oral [**Hospital1 **] (liquid protein supplement) +. + + +Discharge Medications: +1. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous Q 12H (Every 12 Hours) for 7 days. gram +2. Piperacillin-Tazobactam-Dextrs 4.5 gram/100 mL Piggyback Sig: +One (1) Intravenous Q8H (every 8 hours) for 7 days. +3. Sodium Hypochlorite 0.25 % Solution Sig: One (1) Appl +Miscellaneous ASDIR (AS DIRECTED) for 1 days: apply to ischial +wounds only, for one day ([**4-16**]) in [**Hospital1 **] wet to dry dsg changes. +4. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +5. Baclofen 10 mg Tablet Sig: 0.5 Tablet PO TID (3 times a day). + +6. Calcium Carbonate 500 mg Tablet, Chewable Sig: One (1) +Tablet, Chewable PO BID (2 times a day). +7. Citalopram 20 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +8. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) inhalation Inhalation [**Hospital1 **] (2 times a day). +9. Gabapentin 400 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +10. Simethicone 80 mg Tablet, Chewable Sig: One (1) Tablet, +Chewable PO TID (3 times a day) as needed. +11. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +12. Tramadol 50 mg Tablet Sig: 0.5 Tablet PO TID (3 times a +day). +13. Ursodiol 300 mg Capsule Sig: One (1) Capsule PO QDAILY (). +14. Trazodone 50 mg Tablet Sig: 0.5 Tablet PO HS (at bedtime) as +needed. +15. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed. +16. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H +(every 6 hours) as needed. +17. Aluminum-Magnesium Hydroxide 225-200 mg/5 mL Suspension Sig: +15-30 MLs PO QID (4 times a day) as needed. +18. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +19. Ondansetron 4 mg Tablet, Rapid Dissolve Sig: [**2-10**] Tablet, +Rapid Dissolves PO Q8H (every 8 hours) as needed. +20. Warfarin 3 mg Tablet Sig: One (1) Tablet PO once a day. +Tablet(s) + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +UTI with sepsis +Chronic sacral and ischial decubitus ulcerations +Chronic, systolic, heart failure +Hx. PE with SVC filter, on warfarin + + +Discharge Condition: +Stable + + +Discharge Instructions: +Return to the [**Hospital1 18**] Emergency Department for: + +Fever +Hypotension + +Followup Instructions: +Provider: [**Name10 (NameIs) **] SURGERY CLINIC Phone:[**Telephone/Fax (1) 4652**] +Date/Time:[**2106-4-23**] 1:30 + +For evaluation for suprapubic catheter placment: + +Provider: [**Name10 (NameIs) **] UNIT Phone:[**Telephone/Fax (1) 164**] Date/Time:[**2106-4-28**] +9:30 + + + +",35,2106-04-06 07:05:00,2106-04-15 18:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,FEVER," +a/p: 67m h/o t4 paraplegia, recurrent utis [**3-13**] indwelling foley, +multiple stage 4 decubs was admitted to icu initially with fever +to 101.8, transient hypotension that resolved with 3-4l ivf but +continued on sepsis protocol. +. +# fever - felt due to uti and or osteomyelitis. cx. all neg, +but swab suggested colonization with mrsa; also seen on swab, +pseudomonas and enterococcus. emperically treated with +vancomycin and zosyn given this information and prior culture +data that was reviewed here. tagged wbc scan as above. plastic +surgery consult evaluated wounds and felt that pt. did not have +evidence of osteomyelitis. plan two weeks of abx for empiric +treatment for complicated uti. foley replaced. follow up with +[**month/day (2) **] arranged for evaluation for suprapubic catheter. follow +up with plastic surgery also arranged. +. +# hypotension - resolved with ivf and treatment of infection as +above. + +# h/o pe - s/p ivc filter, inr elevated, so warfarin held, then +given 5 po vitamin k given sustained inr over 4.0. inr came +down to 1.8 with this, so warfarin resumed. + +otherwise, home medication regimen continued in hospital for +other chronic medical issues as outlined in pmhx. and in +medication list below. + + ","PRIMARY: [Infection and inflammatory reaction due to indwelling urinary catheter] +SECONDARY: [Unspecified septicemia; Sepsis; Paraplegia; Pressure ulcer, lower back; Pressure ulcer, hip; Chronic systolic heart failure; Urinary tract infection, site not specified; Aortocoronary bypass status; Congestive heart failure, unspecified; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants]" +21202,155154.0,30385,2146-02-24,30384,106349.0,2145-09-12,Discharge summary,"Admission Date: [**2145-9-7**] Discharge Date: [**2145-9-12**] + +Date of Birth: [**2090-7-16**] Sex: M + +Service: MEDICINE + +Allergies: +Cefepime / Cipro + +Attending:[**First Name3 (LF) 3913**] +Chief Complaint: +Hypotension, cough + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +Mr. [**Known lastname 47367**] is a 55 yo male s/p allogeneic stem cell transplant +for AML [**6-/2143**] with chronic GVHD on long-term steroids, DM, hx +of PE on coumadin. +. +He presents to his [**Hospital 3242**] clinic with fatigue for several days, and +anorexia, with about 12-16 hours of worsening shortness of +breath. +. +Endorses increased cough with yellow sputum production and +chills, but no fever. This morning, he reported an acute episode +of dyspnea that did not rapidly improved, and occured with +little amounts of activity and somewhat improved with rest. No +PND/orthopnea. No hemoptysis. +. +He has had no new rashes, and has not had documented fevers. He +has no diarrhea, but has been nauseated without vomiting. He +reports mild epigastric pain. He has a mild headache made +somewhat worse with light, but he feels that this is very +consistent with flares of GVH and not different (has occured he +estimates about 8 times). +. +In clinic SBP 70's, and he was given saline with improvement, +but then the BP decreased down to the 80's. Labs from clinic +showed that Cr increased to 2.9 (baseline 1.1). WBC increased +somewhat. He was transferred to the ED for further evaluation. +. +In the ED, initial vs were: 4 97.6 72 105/73 18 99% He was +given total of 3L of saline, and recent vital signs were 98.8 +129/85 80 16 96% on 2L at time of transfer. A bedside ""shock"" +ultrasound US in ED showed no cardiac effusion, no evidence of +gross RV overload. EKG was not significantly changed. Her INR +was 3.0. Of note, he was also complaining of left sided +shoulder/neck pain associated with shortness of breath and +diaphoresis. +. +For interventions, he received 1 gm vanc and 1gm aztreonam, 40 +mg medrol, and 2 L IVF in clinic, and another liter in the ED. + +Past Medical History: +- AML-M7: s/p matched unrelated allogenic transplant on +[**2143-6-24**] +- Chronic extensive GVHD of skin and liver, liver biopsy [**4-23**] +consistent with GVHD, managed with cyclosporine, steroids, +periodic CellCept, and has received 1 cycle of Rituxan. +- Type 2 DM +- Hyperlipidemia +- H/o AVN bilateral hips +- HTN +- H/o nephrolithiasis, lithotripsy and previous nephrostomy tube +and emergent surgery to repair ureteral damage +- h/o left interpolar renal lesion, followed with MRs +- h/o BCC s/p excision +- h/o SCC left cheek, s/p Mohs' [**5-/2144**] +- h/o multiple back surgeries: Lumbar L5-S1 surgery x 3, and +cervical spine fusion (bone graft, no hardware) +- h/o anterior cervical diskectomy and instrument arthrodesis at +C5-C6 and C6-C7 for degenerative cervical spondylitic disease +with spinal cord compression and foraminal stenosis at C5-C6 and +C6-C7 [**2-/2144**]- Dr. [**Last Name (STitle) 548**] +- Chronic numbness, neuropathic pain in left upper extremity. +- Multilevel compression fractures T11, T12, L1 and mild +compression L3 and L4. +- h/o pulmonary embolism [**11/2144**] on anticoagulated from +[**11/2144**]-present +- h/o RSV [**11/2144**] requiring ICU admission +- h/o OSA, planned BIPAP, followed by Dr. [**Last Name (STitle) 4507**] + +Social History: +Lives with his wife, and one of children, worked as a [**Company 22957**] +technician until [**Month (only) 547**] when he took early retirement and he is +no longer working. Tob: previously smoked 1ppd for many years +but quit 2.5 years ago +EtOH: h/o social use; none recently + +Family History: +Mother died suddenly in her 70s. Father died of unknown cancer +with tumors visible across body. One sister has thyroid cancer. +One brother has diabetes and kidney stones. One sister has +[**Name (NI) 5895**]. + + +Physical Exam: +Tmax: 36.7 ??????C (98.1 ??????F) +Tcurrent: 36.7 ??????C (98.1 ??????F) +HR: 85 (85 - 85) bpm +BP: 101/66(75) {101/66(75) - 101/66(75)} mmHg +RR: 11 (11 - 11) insp/min +SpO2: 97% +Heart rhythm: SR (Sinus Rhythm) +. +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: Regular rate and rhythm, normal S1 + S2, no murmurs, rubs, +gallops +Abdomen: mild RUQ->mid epigastrium tenderness +GU: no foley +Ext: warm, well perfused, 2+ pulses, no clubbing, cyanosis or +edema . No calf or thigh tenderness. +Skin: depigmentation on hands, redness of neck, but no notable +skin changes otherwise. No rashes. + +Pertinent Results: +[**9-9**] CT chest without contrast +IMPRESSION: +1. Mostly resolved parenchymal opacities, leaving several +parenchymal bands which are felt most likely to represent +residua of a prior infectious or inflammatory process. +2. Subacute to chronic rib fractures, including along the right +posterior +seventh rib, where there is faint but suspicious sclerosis +extending further laterally than would usually be expected in +the setting of an uncomplicated rib fracture. In the setting of +prior treated hematological malignancy, the finding of vague +sclerosis raises concern for a bone marrow abnormality such as +myelofibrosis or potentially a form of disease recurrence. +Mostly, however, the bones appear within normal limits. +. +[**9-9**] PFT's +SPIROMETRY + Pre drug Post drug + Actual Pred %Pred Actual %Pred %chg +FVC 3.86 5.05 76 3.83 76 -1 +FEV1 2.83 3.60 79 2.69 75 -5 +FEV1/FVC 73 71 103 70 98 -4 +. +[**9-8**] RUQ US +IMPRESSION: +1. Polyp at neck of gallbladder (1.2cm), which was also seen on +prior +ultrasound scan [**2145-2-9**]. This has not changed significantly +since prior +ultrasound scan, but followup imaging is advised. +. +[**9-8**] Echo +The left atrium is mildly dilated. Left ventricular wall +thickness, cavity size, and global systolic function are normal +(LVEF>55%). Due to suboptimal technical quality, a focal wall +motion abnormality cannot be fully excluded. Tissue Doppler +imaging suggests a normal left ventricular filling pressure +(PCWP<12mmHg). Right ventricular chamber size and free wall +motion are normal. The aortic root is mildly dilated at the +sinus level. The aortic valve leaflets (3) appear structurally +normal with good leaflet excursion and no aortic regurgitation. +The mitral valve appears structurally normal with trivial mitral +regurgitation. There is no mitral valve prolapse. There is +borderline pulmonary artery systolic hypertension. There is an +anterior space which most likely represents a fat pad. +. +Micro: +[**9-8**] CMV VL negative +[**9-8**] sputum: oropharyngeal flora +[**9-8**] urine cx negative +[**9-8**] viral screen and cx negative +[**9-7**] blood cx negative +. +ON ADMISSION: +[**2145-9-7**] 01:05PM BLOOD WBC-11.1* RBC-4.39* Hgb-16.0 Hct-49.0 +MCV-112* MCH-36.5* MCHC-32.7 RDW-14.9 Plt Ct-264 +[**2145-9-7**] 01:05PM BLOOD Neuts-85.1* Lymphs-7.0* Monos-5.2 Eos-2.5 +Baso-0.3 +[**2145-9-7**] 01:05PM BLOOD PT-30.5* INR(PT)-3.0* +[**2145-9-7**] 01:05PM BLOOD UreaN-28* Creat-2.9*# Na-140 K-4.4 Cl-101 +HCO3-29 AnGap-14 +[**2145-9-7**] 01:05PM BLOOD ALT-24 AST-20 LD(LDH)-201 CK(CPK)-37* +AlkPhos-155* TotBili-0.3 +[**2145-9-7**] 01:05PM BLOOD cTropnT-0.05* +[**2145-9-7**] 01:05PM BLOOD Albumin-4.2 Calcium-9.3 Phos-2.6* Mg-2.4 +[**2145-9-7**] 08:13PM BLOOD Lactate-1.9 +. +ON DISCHARGE: +[**2145-9-12**] 05:40AM BLOOD WBC-7.2 RBC-3.45* Hgb-12.5* Hct-38.3* +MCV-111* MCH-36.2* MCHC-32.7 RDW-15.0 Plt Ct-211 +[**2145-9-12**] 05:40AM BLOOD Neuts-68.8 Lymphs-17.2* Monos-7.9 +Eos-5.7* Baso-0.4 +[**2145-9-12**] 05:40AM BLOOD Plt Ct-211 +[**2145-9-12**] 05:40AM BLOOD Glucose-80 UreaN-18 Creat-0.9 Na-143 +K-3.7 Cl-104 HCO3-30 AnGap-13 +[**2145-9-12**] 05:40AM BLOOD ALT-25 AST-18 LD(LDH)-181 AlkPhos-112 +TotBili-0.2 +[**2145-9-12**] 05:40AM BLOOD Calcium-9.0 Phos-2.8 Mg-2.1 UricAcd-4.6 + +Brief Hospital Course: +55 y/o male with ?viral syndrome vs. other atypical infection +with hypotension that is suspected to be hypovolemia or adrenal +insufficiency, with acute renal failure. +. +# Lethargy: concern for viral syndrome, including activation of +CMV, or a respiratory virus. He has been known EBV+ in the past. +This could also be related to sensation of dyspnea that he has +been having, and warranted further cardiovascular and pulmonary +work-up in parallel with the infectious work-up. In the ICU, +continued broad spectrum antibiotics of vancomycin and aztreonam +(given allergy). Infectious workup largely negative including +CMV VL, respiratory panel, EBV VL, fungal markers, blood +cultures, urine cultures, CT chest. Pt's lethargy improved with +IVFs, antibiotics, and stress dose steroids. Did not ever need +pressors. +. +# Dyspnea/Cough: Concern for infectious process. Regarding VTE, +his risk should be reduced with therapeutic INR, though the +concern for coumadin failure merits consideration, though would +be unlikely and he has no other signs and symptoms of DVT. PFTs +completed [**9-9**], with official report pending at time of this +summary. CT chest showing resolving parenchymal processes, +resolving infectious/inflammatory process. Continued broad +spectrum antibiotics initially. When no infiltrate noted on CXR, +decreased ABX to 5 days of azithromycin for treatment of +bronchitis. +. +# Hypotension: A bedside ""shock"" ultrasound US in ED showed no +cardiac effusion, no evidence of gross RV overload. EKG +unchanged. Patient's hypotension was fluid/stress dose steroids +responsive. Initially given stress dose steroids with plans to +resume home dose. Also given IVF repletion. BPs normalized. +Likely etiology was slight adrenal insufficiency in setting of +viral syndrome despite negative infectious workup. Patient +discharged with prednisone 7.5 mg daily. +. +# Acute Renal Failure: Likely pre-renal azotemia. Improved with +IVFs. Cr 0.9 on discharge. +. +# Mild epigastric/RUQ tenderness: No laboratory e/o hepatitis. +RUQ US showing polyp at neck of gallbladder (1.2cm), which was +also seen on prior ultrasound scan [**2145-2-9**]. No other findings +to explain epigastric pain. This pain has resolved on discharge. +. +# Pulmonary Embolism [**11-23**]: continued coumadin with INR goal +[**1-19**]. + +# Diabetes: Continued NPH 12 units [**Hospital1 **], with close sugar +monitoring and diabetic diet. + +Medications on Admission: +ACYCLOVIR - 400 mg Tablet - 1 Tablet(s) by mouth three times a +day +BUDESONIDE [ENTOCORT EC] - (Dose adjustment - no new Rx) - 3 mg +Capsule, Sust. Release 24 hr - 1 (One) Capsule(s) by mouth twice +a day +FOLIC ACID - (Dose adjustment - no new Rx) - 1 mg Tablet - 1 +(One) Tablet(s) by mouth once a day +HYDROMORPHONE - 2 mg Tablet - [**12-18**] Tablet(s) by mouth every [**3-22**] +hours as needed for pain +INSULIN LISPRO [HUMALOG] - SS +LISINOPRIL - (Dose adjustment - no new Rx) - 5 mg Tablet - 1 +Tablet(s) by mouth once a day +METOPROLOL TARTRATE - 25 mg Tablet - 1 (One) Tablet(s) by mouth +twice a day +OXYCODONE - 20 mg Tablet Sustained Release 12 hr - 3 (Three) +Tablet(s) by mouth every morning (60 mg), 1 tablet every 2pm (20 +mg) and 3 tablets every evening (60 mg) +PANTOPRAZOLE [PROTONIX] - 40 mg Tablet, Delayed Release (E.C.) - +1 Tablet(s) by mouth once day +PREDNISONE - 2.5 mg Tablet - 2 (Two) Tablet(s) by mouth once a +day +RISEDRONATE [ACTONEL] - 35 mg Tablet q Saturday +TESTOSTERONE [ANDROGEL] - 50 mg/5 gram (1 %) Gel in Packet - +Apply to upper torso once daily +WARFARIN [COUMADIN] - (Dose adjustment - no new Rx) - 2.5 mg +Tablet - 2 (Two) Tablet(s) by mouth once a day or as directed +CHOLECALCIFEROL (VITAMIN D3) [DELTA D3] - (Dose adjustment - no +new Rx) - 400 unit Tablet - 1 Tablet(s) by mouth DAILY (Daily) +INSULIN NPH HUMAN RECOMB - (Prescribed by Other Provider) - 100 +unit/mL Suspension - 12 units twice a day Please take first dose +in the morning and the second dose at bedtime + +Discharge Medications: +1. Azithromycin 250 mg Tablet Sig: One (1) Tablet PO Q24H (every +24 hours) for 2 days. +Disp:*2 Tablet(s)* Refills:*0* +2. Acyclovir 200 mg Capsule Sig: Two (2) Capsule PO Q8H (every 8 +hours). +3. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +5. OxyContin 60 mg Tablet Sustained Release 12 hr Sig: One (1) +Tablet Sustained Release 12 hr PO twice a day: QAM and QPM. +6. OxyContin 20 mg Tablet Sustained Release 12 hr Sig: One (1) +Tablet Sustained Release 12 hr PO once a day: at 1400 every day. + +7. Warfarin 5 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM. +8. Budesonide 3 mg Capsule, Sust. Release 24 hr Sig: One (1) +Capsule, Sust. Release 24 hr PO twice a day. +9. Prednisone 2.5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily): For total 7.5 mg daily. +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +11. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +12. Actonel 35 mg Tablet Sig: One (1) Tablet PO once a week: On +Saturdays. +13. AndroGel 1 %(50 mg/5 gram) Gel in Packet Sig: One (1) packet +Transdermal once a day: Apply to upper torso once daily as +directed. +14. Insulin NPH Human Recomb 100 unit/mL Suspension Sig: Twelve +(12) units Subcutaneous twice a day. +15. Insulin Lispro 100 unit/mL Solution Sig: Varied units +Subcutaneous four times a day: As per home sliding scale. + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary diagnosis: +Hypotension/adrenal insufficiency +Bronchitis +Acute renal failure +. +Secondary diagnosis: +AML s/p MUD allogeneic SCT [**6-/2143**] +Chronic GVHD of skin/liver +h/o PE +Diabetes mellitus + + +Discharge Condition: +Stable, afebrile, BP 113/76, RR 16, sats 96% on RA, INR 1.8. + + +Discharge Instructions: +You were admitted with fatigue, shortness of breath, cough, low +blood pressure and acute renal failure. We were concerned for +early sepsis and you were in the ICU initially. You received +broad spectrum antibiotics and stress dose steroids, but a full +workup (including viral swabs, cultures, ECHO, and CT chest) +were unrevealing. CT chest showed resolving infiltrates and your +symptoms improved so the antibiotics were switched to +azithromycin for presumed bronchitis. Your prednisone was +increased due to presumed mild adrenal insufficiency. +. +The following medication changes were made: +1) Prednisone increased to 7.5mg daily +2) Azithromycin (antibiotic) started, to be completed as +outpatient +3) Your lisinopril (blood pressure medication) and metoprolol +were discontinued. Do NOT resume these medications until +speaking to Dr. [**Last Name (STitle) **]. +. +You need to have your INR checked on Tuesday, [**2145-9-14**]. You also +need to follow up with Dr. [**Last Name (STitle) **] and [**First Name8 (NamePattern2) 3235**] [**Last Name (NamePattern1) 3236**] within the +next week. Please call their office tomorrow to make this +appointment. +. +of the following symptoms: fever, chills, shortness of breath, +difficulty breathing, abdominal pain, cough, flu symptoms, or +any other worrisome symptoms. + + +Followup Instructions: +You need to have your INR checked on Tuesday, [**2145-9-14**]. +. +Please call Dr. [**Last Name (STitle) **] and [**First Name8 (NamePattern2) 3235**] [**Last Name (NamePattern1) 72254**] office to make an +appointment to be seen later this week. They can be reached at +[**Telephone/Fax (1) 3241**]. + + + +Completed by:[**2145-9-17**]",165,2145-09-07 20:37:00,2145-09-12 16:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,SEPSIS," +55 y/o male with ?viral syndrome vs. other atypical infection +with hypotension that is suspected to be hypovolemia or adrenal +insufficiency, with acute renal failure. +. +# lethargy: concern for viral syndrome, including activation of +cmv, or a respiratory virus. he has been known ebv+ in the past. +this could also be related to sensation of dyspnea that he has +been having, and warranted further cardiovascular and pulmonary +work-up in parallel with the infectious work-up. in the icu, +continued broad spectrum antibiotics of vancomycin and aztreonam +(given allergy). infectious workup largely negative including +cmv vl, respiratory panel, ebv vl, fungal markers, blood +cultures, urine cultures, ct chest. pts lethargy improved with +ivfs, antibiotics, and stress dose steroids. did not ever need +pressors. +. +# dyspnea/cough: concern for infectious process. regarding vte, +his risk should be reduced with therapeutic inr, though the +concern for coumadin failure merits consideration, though would +be unlikely and he has no other signs and symptoms of dvt. pfts +completed [**9-9**], with official report pending at time of this +summary. ct chest showing resolving parenchymal processes, +resolving infectious/inflammatory process. continued broad +spectrum antibiotics initially. when no infiltrate noted on cxr, +decreased abx to 5 days of azithromycin for treatment of +bronchitis. +. +# hypotension: a bedside ""shock"" ultrasound us in ed showed no +cardiac effusion, no evidence of gross rv overload. ekg +unchanged. patients hypotension was fluid/stress dose steroids +responsive. initially given stress dose steroids with plans to +resume home dose. also given ivf repletion. bps normalized. +likely etiology was slight adrenal insufficiency in setting of +viral syndrome despite negative infectious workup. patient +discharged with prednisone 7.5 mg daily. +. +# acute renal failure: likely pre-renal azotemia. improved with +ivfs. cr 0.9 on discharge. +. +# mild epigastric/ruq tenderness: no laboratory e/o hepatitis. +ruq us showing polyp at neck of gallbladder (1.2cm), which was +also seen on prior ultrasound scan [**2145-2-9**]. no other findings +to explain epigastric pain. this pain has resolved on discharge. +. +# pulmonary embolism [**11-23**]: continued coumadin with inr goal +[**1-19**]. + +# diabetes: continued nph 12 units [**hospital1 **], with close sugar +monitoring and diabetic diet. + + ","PRIMARY: [Unspecified septicemia] +SECONDARY: [Acute kidney failure, unspecified; Glucocorticoid deficiency; Acute myeloid leukemia, in remission; Complications of transplanted bone marrow; Chronic graft-versus-host disease; Severe sepsis; Adrenal cortical steroids causing adverse effects in therapeutic use; Acute bronchitis; Surgical operation with transplant of whole organ causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Personal history of venous thrombosis and embolism; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Long-term (current) use of steroids]" +23161,115895.0,17796,2138-08-03,17795,168634.0,2138-07-27,Discharge summary,"Admission Date: [**2138-7-18**] Discharge Date: [**2138-7-27**] + +Date of Birth: [**2055-3-1**] Sex: M + +Service: MEDICINE + +Allergies: +Phenylephrine + +Attending:[**First Name3 (LF) 1711**] +Chief Complaint: +chest pain + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +83 yo Russian speaking male with a history of CAD and a recent +NSTEMI reportedly complicated by cardiogenic shock (hospitalized +at [**Hospital3 **] and discharged to rehab yesterday) presents +from rehab after experiencing CP and subsequent hypotension +following NTG adminstration. At [**Hospital3 **] apparently +underwent cath which demonstrated anatomy not ammendable to +stenting. At rehab today, experienced chest pain and was given +ASA and NTG. He subsequently became hypotensive with SBPs +reportedly in the 80s. Per wife for many years pt had chest +discomfort lasting about 5-10 minutes about once a month at home +that usually resolves with NTG. however for the past 5-6 days he +has had it everyday and at times more than once a day at rest. +this morning he was in bed when chest pain began. after he took +ntg he began to feel unwell and bp was noted to be in the 80s. +he apparently also has been having blood streak in the stool and +urine since admitted at [**Hospital3 **] but was evaluated there. +she also states he has exertional dyspnea on going up the stairs +but denies syncope. pt apparent has not had any fever, chill, +rigor. he however does have a cough with minimal sputum +production. +. +In the [**Hospital1 18**] ED, the pt's initial vitals were stable. He denied +any further chest pain. A chest x-ray was concering for possible +pneumonia and the patient was treated with antibiotics. However +he's afebrile and has a normal wcc. He was also evaluated in the +ED by cardiology who advised against emperic anticoagulation. +The pt is now admitted to the CCU for close monitoring. His most +recent vitals prior to transfer were: HR 60, RR 23, 110/47, 97% +4L +. +On review of systems, s/he denies any prior history of stroke, +TIA, deep venous thrombosis, pulmonary embolism, bleeding at the +time of surgery, myalgias, joint pains, cough, hemoptysis, black +stools or red stools. S/he denies recent fevers, chills or +rigors. S/he denies exertional buttock or calf pain. All of the +other review of systems were negative. + + +Past Medical History: +1. CARDIAC RISK FACTORS: Hypertension +2. CARDIAC HISTORY: +-PERCUTANEOUS CORONARY INTERVENTIONS: +3. OTHER PAST MEDICAL HISTORY: +. +MR +AS, severe +CHF, systolic and diastolic dysfunction, +Recurrent MI with cardiogenic shock [**2133-8-7**]. +Multiple PCI procedures +PAD with IC +Right foot plantar ulcer +CRI. +Bronchiectasis/emphysema/recurrent bronchitis +Diabetic neuropathy, possible early diabetic nephropathy +Chronic recurrent left ear infection + + +Social History: +Lives at home with wife. +-Tobacco history: Denies. +-ETOH: Rare social EtOH. +-Illicit drugs: + + +Family History: +Noncontributory + +Physical Exam: +Temp 37.3, hr 70/min, bp 107/70, rr 16/min, sats 96% on ra +GENERAL: appears in no apparent distress. Mood, affect +appropriate. +[**Month/Day/Year 4459**]: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. No xanthalesma. + +NECK: Supple, jvp mildly elevated in a 30% angle +CARDIAC: rrr, nl s1, faint s2, [**5-12**] ejection systolic murmur in +right second intercostal space with radiation to neck. +LUNGS: reduce air entry bilaterally with expiratory wheeze. +ABDOMEN: soft, non tender, nl bs +EXTREMITIES: No c/c/e. No femoral bruits. +SKIN: No stasis dermatitis, ulcers, scars, or xanthomas. +PULSES: 1+ dp and pt pulses + + +Pertinent Results: +ADMISSION LABS: + +CBC: +[**2138-7-18**] 01:39PM BLOOD WBC-5.0 RBC-3.18*# Hgb-9.6*# Hct-28.9*# +MCV-91 MCH-30.1 MCHC-33.1 RDW-16.2* Plt Ct-340# +[**2138-7-18**] 01:39PM BLOOD Neuts-78.4* Lymphs-14.4* Monos-4.0 +Eos-2.7 Baso-0.5 + +[**2138-7-27**] BLOOD WBC-8.7 Hgb-8.1*# Hct-24.6*# Plt Ct-191# + +COAGS: +[**2138-7-18**] 01:39PM BLOOD PT-13.8* PTT-24.3 INR(PT)-1.2* + +CHEMISTRIES: +[**2138-7-18**] 01:39PM BLOOD Glucose-289* UreaN-32* Creat-1.6* Na-135 +K-4.9 Cl-98 HCO3-28 AnGap-14 + +[**2138-7-27**] BLOOD Glucose-83* UreaN-35* Creat-1.6* Na-139 K-4.0 +Cl-103 HCO3-26 + +LFTS: +[**2138-7-19**] 06:00AM BLOOD ALT-27 AST-22 LD(LDH)-213 CK(CPK)-61 +AlkPhos-85 TotBili-0.6 + +CEs: +[**2138-7-18**] 01:39PM BLOOD cTropnT-0.05* +[**2138-7-18**] 01:39PM BLOOD CK-MB-NotDone +[**2138-7-18**] 07:08PM BLOOD CK-MB-NotDone cTropnT-0.05* +[**2138-7-19**] 06:00AM BLOOD CK-MB-NotDone cTropnT-0.06* +[**2138-7-22**] 05:15AM BLOOD CK-MB-NotDone cTropnT-0.04* +[**2138-7-18**] 01:39PM BLOOD CK(CPK)-71 +[**2138-7-18**] 07:08PM BLOOD CK(CPK)-64 +[**2138-7-18**] 07:08PM BLOOD Calcium-8.2* Phos-2.8 Mg-2.1 + +IRON STUDIES: +[**2138-7-19**] 06:00AM BLOOD calTIBC-247* VitB12-918* Folate-11.9 +Ferritn-240 TRF-190* + +URINE STUDIES: +[**2138-7-22**] 06:30PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.009 +[**2138-7-22**] 06:30PM URINE Blood-NEG Nitrite-NEG Protein-NEG +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-5.0 Leuks-NEG += += += += += += += += +================================================================ +MICRO: +[**2138-7-25**] Urine Cx: +URINE CULTURE (Final [**2138-7-27**]): + ESCHERICHIA COLI. 10,000-100,000 ORGANISMS/ML.. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ESCHERICHIA COLI + | +AMPICILLIN------------ =>32 R +AMPICILLIN/SULBACTAM-- 16 I +CEFAZOLIN------------- <=4 S +CEFEPIME-------------- <=1 S +CEFTAZIDIME----------- <=1 S +CEFTRIAXONE----------- <=1 S +CEFUROXIME------------ 16 I +CIPROFLOXACIN--------- =>4 R +GENTAMICIN------------ <=1 S +MEROPENEM-------------<=0.25 S +NITROFURANTOIN-------- <=16 S +PIPERACILLIN---------- 64 I +PIPERACILLIN/TAZO----- <=4 S +TOBRAMYCIN------------ <=1 S +TRIMETHOPRIM/SULFA---- <=1 S + +[**7-25**], [**7-26**] Blood Cx: Pending += += += += += += += += +================================================================ +[**7-18**] TTE +The left atrium is mildly dilated. There is mild symmetric left +ventricular hypertrophy. LV systolic function appears depressed +(ejection fraction 30 percent) secondary to akinesis of the +posterior wall and anterior septum, and hypokinesis of the rest +of the left ventricle. Right ventricular chamber size and free +wall motion are normal. The aortic valve leaflets are severely +thickened/deformed. There is severe aortic valve stenosis. The +mitral valve leaflets are mildly thickened. There is no mitral +valve prolapse. Moderate (2+) mitral regurgitation is seen. The +tricuspid valve leaflets are mildly thickened. The supporting +structures of the tricuspid valve are thickened/fibrotic. There +is borderline pulmonary artery systolic hypertension. There is +no pericardial effusion. + +Compared with the findings of the prior study (images reviewed) +of [**2138-2-21**], the left ventricular ejection fraction is +further reduced. + +CXR [**7-19**] +The current study demonstrates left basilar opacity which is new +since [**2138-4-17**], and although appears to be smaller than on +[**2138-7-18**], is consistent with a new left lower lobe +infiltrate that might be worrisome for infectious process. No +short interval change in the cardiomediastinal silhouette is +demonstrated. There is no evidence of failure, pleural effusion, +or pneumothorax. + +CXR [**7-25**] +FINDINGS: In comparison with study of [**7-19**], there is increased +opacification +at the right base medially with silhouetting of the heart +border. Although +some of this may merely represent atelectasis, the appearance is +worrisome for +developing middle lobe pneumonia. Unfortunately, the lateral +view is somewhat +limited and does not adequately show this region. + +No evidence of vascular congestion. + +Video Swallow: +Gross aspiration of nectar thick liquids which the patient was +sensate. + + +Brief Hospital Course: +83 year old man with complex medical issues including Diasolic +and systolic CHF, severe AS, CKD, COPD and DM-2, PVD and chronic +ulcers presents from nursing facility after taking NTG for his +chest pain that resulted in hypotension that subsequently +resolved spontanously. Pt also has new AF at [**Hospital3 5097**], started on +amiodarone, persistant hematuria and anemia. +. +# CAD: Patient with recent NSTEMI reportedly complicated by +cardiogenic shock (hospitalized at [**Hospital3 **] and +discharged to rehab one day prior to admission). He reportly +had CP at rehab and was given SLN with subsequent hypotension. +At [**Hospital3 **] the patient underwent cath that demonstrated +clean LM, LAD total occulsion, LCx 50%, RCA 60%, LAD collaterals +being filled by RCA and anatomy was not ammendable to stenting. +On arrival he was chest pain free. The patient was medically +managed with high dose statin, BB and ASA. His cath films were +reviewed by both cardiac surgery and interventional cardiology. +The plan is to continue medical mangement given his lesions are +not amenable to either PCI or CABG. He had 2 episodes of chest +pain during his hospital course associated with no ECG changes +or cardiac enzyme elevation. The pain was relieved with IV +morphine. +. +#. Severe Aortic Stenosis: ECHO revealed a valve area of +0.8-1.0cm2 with a mean gradient of 23. He was evaluated by +Cardiac Surgery who as noted above did not recommend CABG/AVR. +Notably, the patient's severe AS makes treating his chest pain +difficult since he is pre-load dependent and medications such as +sub-lingial nitroglycerin can result in hypotension. Thus, this +medication should be avoided. + +# Atrial Fibrillation: His AF was noted during his admission to +[**Hospital3 5097**] in mid [**Month (only) 116**]. He was started on an amiodorone gtt at OSH +and discharged to rehab on 200mg [**Hospital1 **]. His dose was further +reduced to 200 mg daily during this hospitalization. He was also +continued on metoprolol. + +# Chronic Systolic Congestive Heart Failure: The patient +underwent ECHO that showed and EF of 30%. There was no evidence +of overload clinically. He was continued on lasix, +spironolactone, lisinopril and metoprolol. + +# Urinary Tract Infection: Patient found to have asymptomatic +UTI. Gram neg rods in urine. He was started on cipro on [**7-26**], +but cx grew E. Coli resistant to cipro. He was changed to +Bactrim DS 1tab [**Hospital1 **] on [**7-27**] and should complete a total 7 day +course. + +# Left lower lob infiltrate: This was felt to be secondary to +aspiration pneumonitis since the patient was shown to aspirate +during speech and swallow evaluation. Given he remained afebrile +without leukocytosis he was not treated with ABX for this +condition. Patient was started on a diet of pureed solids and +honey thickened liquids to prevent further aspiration events. + +# Aspiration: Patient underwent video swallow that demonstrated +aspiration. Speech and swallow had the following recs: +1. PO diet: pureed solids, honey thick liquids +2. PO meds: crushed in puree +3. Q4 oral care +4. 1:1 assist with meals to maintain aspiration precautions +They also recommend f/u by swallow therapy in rehab setting and +will require videoswallow study in [**2-7**] weeks to consider diet +upgrade. + +# Iron deficiency Anemia: The patient's Hct in [**3-17**] 40, but on +admission Hct was 28 and has remained stable. Notably, he has +had multiple guiac positive stool and plan is for him to undergo +outpatient EGD and colonoscopy on [**2138-7-28**]. However, the patient +and family would like to postpone the GI workup until after +rehab. They were given the phone number for [**Hospital **] clinic to +reschedule if they would like to. The patient was continued on +PPI and Iron. + +#) Hematuria: On admission the patient had hematuria that had +started during his prior admission to [**Hospital3 **]. On [**7-20**] +he was seen by urology and removed a large amount of old clot +from his foley. There was no active bleeding. His foley was +changed to a larger diameter foley. A repeat UA [**7-22**] was +negative for blood. +Patient should follow up as an outpatient with Dr. [**Last Name (STitle) 27027**]. The +Urology contact number is [**Telephone/Fax (1) 164**]. + +#) Acute on Chronic Kidney Disease: The patient's creatinine +was 1.6 on admission and has remained stable. He is at his +baseline. + +#) DM: The patient's insulin was increased to his home dose of +50U lantus with improved glucose control. His home glyburide and +precose were held during his admission and was covered with an +ISS. + +Medications on Admission: +simvastatsin 80mg daily +aspirin 325 mg daily +Gabapentin 300 mg Capsule Sig: Two (2) Capsule PO Q12H +amiodarone 200mg [**Hospital1 **] +allopurinol 150mg daily +lasix 40mg daily +lisinopril 5mg daily +metoprolol 50mg [**Hospital1 **] +spironolactone 12.5mg daily +lantus 40units daily and sliding scale + + +Discharge Medications: +1. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +2. Allopurinol 100 mg Tablet Sig: 1.5 Tablets PO DAILY (Daily). + +3. Spironolactone 25 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). + +4. Gabapentin 300 mg Capsule Sig: Two (2) Capsule PO Q12H (every +12 hours). +5. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Simvastatin 40 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +7. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +8. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +9. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO DAILY (Daily). +10. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +11. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +12. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +13. Outpatient Speech/Swallowing Therapy +Please reassess swallowing on [**2138-7-30**] thanks +14. Lantus 100 unit/mL Solution Sig: Fifty (50) U Subcutaneous +at bedtime. +15. Insulin Lispro 100 unit/mL Solution Sig: per sliding scale +Subcutaneous four times a day: please follow attached sliding +scale. +16. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +17. Simethicone 80 mg Tablet, Chewable Sig: One (1) Tablet, +Chewable PO QID (4 times a day) as needed for gas. +18. Polyethylene Glycol 3350 100 % Powder Sig: One (1) PO BID +(2 times a day) as needed for constipation. +19. Senna 8.6 mg Tablet Sig: 1-2 Tablets PO BID (2 times a day) +as needed for constipation. +20. Bactrim DS 160-800 mg Tablet Sig: One (1) Tablet PO twice a +day for 7 days: day1: [**7-27**]. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital **] rehab + +Discharge Diagnosis: +Primary: +-Coronary Artery Disease +-Aortic Stenosis +-Hematuria +-Acute on chronic Renal Failure +-Urinary Tract Infection +Secondary: +Chronic systolic heart failure +Diabetes Mellitus Type 2 + + +Discharge Condition: +stable + + +Discharge Instructions: +You had chest pain and was transferred from [**Hospital3 580**] for evaluation. You were evaluated by cardiac surgery +for a possible bypass and aortic valve replacement. At this +time, it is not recommended that you get this surgery. We do not +think your chest pain is related to your heart. Please take +tylenol if you develop the pain. You will need to see Dr. [**First Name (STitle) 572**] +for evaluation of blood in your stools and a urologist for blood +in your urine. +A colonoscopy and endoscopy was scheduled for [**7-28**] to +evaluate bleeding and pain. However, you requested to postpone +the procedure for a few weeks while you are at rehab. Please +call GI: ([**Telephone/Fax (1) 2233**] to reschedule. + +You were seen by a speech therapist who felt that you were +aspirating food into your lungs. You were started on a honey +thick liquids and pureed food diet. Intravenous fluids were +started to prevent dehydration. You will need to be re evaluated +in about a week to determine if you are still aspirating. + +You also had a UTI and was started on bactrim DS 1 tab twice a +day which you should continue for 7 days. + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +or 6 pounds in 3 days. +Adhere to 2 gm sodium diet + +Followup Instructions: +Cardiology: +[**First Name8 (NamePattern2) 1026**] [**Doctor Last Name 1016**] Phone: [**Telephone/Fax (1) 62**] Date/Time: [**8-28**] at 1:20pm. + +Urology: +Dr. [**Last Name (STitle) 770**] Phone: [**Telephone/Fax (1) 164**] Please make f/u as outpt to +evaluate hematuria. [**9-22**] at 1:10pm. [**Hospital Ward Name 23**] Clinical +Center, [**Location (un) 470**]. + +Gastroenterology: +Colonoscopy and EGD: Monday [**7-28**] at 11:30am. [**Hospital Ward Name 1950**] 3 on +[**Hospital Ward Name 516**]. Dr. [**First Name8 (NamePattern2) 449**] [**Last Name (NamePattern1) 452**] will do procedure. +However, you requested to have it postponed for a few weeks +while you recover at rehab. Please call GI: ([**Telephone/Fax (1) 2233**] to +reschedule your appointment. + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 4465**], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2138-7-31**] 3:00 +Podiatry: +Provider: [**First Name11 (Name Pattern1) **] [**Initial (NamePattern1) **] [**Last Name (NamePattern4) 542**], DPM Phone:[**Telephone/Fax (1) 543**] +Date/Time:[**2138-8-20**] 1:30 +Provider: [**Name10 (NameIs) 1571**] FUNCTION LAB Phone:[**Telephone/Fax (1) 609**] +Date/Time:[**2138-8-21**] 10:10 + + + +Completed by:[**2138-7-27**]",7,2138-07-18 16:20:00,2138-07-27 14:20:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,CHEST PAIN," +83 year old man with complex medical issues including diasolic +and systolic chf, severe as, ckd, copd and dm-2, pvd and chronic +ulcers presents from nursing facility after taking ntg for his +chest pain that resulted in hypotension that subsequently +resolved spontanously. pt also has new af at [**hospital3 5097**], started on +amiodarone, persistant hematuria and anemia. +. +# cad: patient with recent nstemi reportedly complicated by +cardiogenic shock (hospitalized at [**hospital3 **] and +discharged to rehab one day prior to admission). he reportly +had cp at rehab and was given sln with subsequent hypotension. +at [**hospital3 **] the patient underwent cath that demonstrated +clean lm, lad total occulsion, lcx 50%, rca 60%, lad collaterals +being filled by rca and anatomy was not ammendable to stenting. +on arrival he was chest pain free. the patient was medically +managed with high dose statin, bb and asa. his cath films were +reviewed by both cardiac surgery and interventional cardiology. +the plan is to continue medical mangement given his lesions are +not amenable to either pci or cabg. he had 2 episodes of chest +pain during his hospital course associated with no ecg changes +or cardiac enzyme elevation. the pain was relieved with iv +morphine. +. +#. severe aortic stenosis: echo revealed a valve area of +0.8-1.0cm2 with a mean gradient of 23. he was evaluated by +cardiac surgery who as noted above did not recommend cabg/avr. +notably, the patients severe as makes treating his chest pain +difficult since he is pre-load dependent and medications such as +sub-lingial nitroglycerin can result in hypotension. thus, this +medication should be avoided. + +# atrial fibrillation: his af was noted during his admission to +[**hospital3 5097**] in mid [**month (only) 116**]. he was started on an amiodorone gtt at osh +and discharged to rehab on 200mg [**hospital1 **]. his dose was further +reduced to 200 mg daily during this hospitalization. he was also +continued on metoprolol. + +# chronic systolic congestive heart failure: the patient +underwent echo that showed and ef of 30%. there was no evidence +of overload clinically. he was continued on lasix, +spironolactone, lisinopril and metoprolol. + +# urinary tract infection: patient found to have asymptomatic +uti. gram neg rods in urine. he was started on cipro on [**7-26**], +but cx grew e. coli resistant to cipro. he was changed to +bactrim ds 1tab [**hospital1 **] on [**7-27**] and should complete a total 7 day +course. + +# left lower lob infiltrate: this was felt to be secondary to +aspiration pneumonitis since the patient was shown to aspirate +during speech and swallow evaluation. given he remained afebrile +without leukocytosis he was not treated with abx for this +condition. patient was started on a diet of pureed solids and +honey thickened liquids to prevent further aspiration events. + +# aspiration: patient underwent video swallow that demonstrated +aspiration. speech and swallow had the following recs: +1. po diet: pureed solids, honey thick liquids +2. po meds: crushed in puree +3. q4 oral care +4. 1:1 assist with meals to maintain aspiration precautions +they also recommend f/u by swallow therapy in rehab setting and +will require videoswallow study in [**2-7**] weeks to consider diet +upgrade. + +# iron deficiency anemia: the patients hct in [**3-17**] 40, but on +admission hct was 28 and has remained stable. notably, he has +had multiple guiac positive stool and plan is for him to undergo +outpatient egd and colonoscopy on [**2138-7-28**]. however, the patient +and family would like to postpone the gi workup until after +rehab. they were given the phone number for [**hospital **] clinic to +reschedule if they would like to. the patient was continued on +ppi and iron. + +#) hematuria: on admission the patient had hematuria that had +started during his prior admission to [**hospital3 **]. on [**7-20**] +he was seen by urology and removed a large amount of old clot +from his foley. there was no active bleeding. his foley was +changed to a larger diameter foley. a repeat ua [**7-22**] was +negative for blood. +patient should follow up as an outpatient with dr. [**last name (stitle) 27027**]. the +urology contact number is [**telephone/fax (1) 164**]. + +#) acute on chronic kidney disease: the patients creatinine +was 1.6 on admission and has remained stable. he is at his +baseline. + +#) dm: the patients insulin was increased to his home dose of +50u lantus with improved glucose control. his home glyburide and +precose were held during his admission and was covered with an +iss. + + ","PRIMARY: [Subendocardial infarction, subsequent episode of care] +SECONDARY: [Acute kidney failure, unspecified; Pneumonitis due to inhalation of food or vomitus; Urinary tract infection, site not specified; Chronic combined systolic and diastolic heart failure; Injury to bladder and urethra, without mention of open wound into cavity; Acute posthemorrhagic anemia; Blood in stool; Coronary atherosclerosis of native coronary artery; Intermediate coronary syndrome; Congestive heart failure, unspecified; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Bronchiectasis without acute exacerbation; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Atherosclerosis of native arteries of the extremities with ulceration; Diabetes with peripheral circulatory disorders, type II or unspecified type, not stated as uncontrolled; Peripheral angiopathy in diseases classified elsewhere; Mitral valve insufficiency and aortic valve stenosis; ; Hematuria, unspecified; Iron deficiency anemia, unspecified; Chronic total occlusion of coronary artery; Other constipation; Atrial fibrillation; Unspecified accident; Long-term (current) use of insulin]" +23657,164590.0,13516,2143-04-08,13515,134743.0,2142-10-25,Discharge summary,"Admission Date: [**2142-10-22**] Discharge Date: [**2142-10-25**] + +Date of Birth: [**2112-11-14**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Watermelon / Almond Oil + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +Nausea, vomiting + +Major Surgical or Invasive Procedure: +None + +History of Present Illness: +29M h/o Type I Diabetes, c/b gastroparesis, erosive gastritis +with h/o upper GI bleed. Presents with n/v, malaise after an +EtOH binge. +. +Pt states that he was in his USOH until Saturday. He had 4 beers +and 3 rum & Coke. Afterwards, has had nausea & vomiting. +. +He also has since been non-compliant with his insulin, missing +several doses of insulin over the past few days. Last evening, +did not take any NPH or regular insulin. +. +ROS otherwise significant for a cough over the past several +days, minimally productive of scant greenish sputum. Otherwise, +denies f/c/s. No dysuria. No CP, SOB, abd pain. +. +In ED, fingerstick blood sugar 422 and BP 235/104. AG 19, +ketones in urine, but no evidence of UTI. Started on IV insulin +gtt, received 3L NS. Labetalol 5mg IV x 2 with SBP down to 170s +systolic. + +Past Medical History: +1. Type I diabetes mellitus, uncontrolled. Last HbA1c 10.8 +[**2142-5-3**]. Followed by Dr. [**Last Name (STitle) 9835**] at [**Last Name (un) **]. Complicated by +gastroparesis, nephropathy. +2. Erosive gastritis per EGD [**2137**]. Noncompliant with GI follow +up for EGD after [**2141**] hospitalization/elopement. Noncompliant +with PPI. +3. Hypertension, uncontrolled +4. Chronic renal insufficiency, baseline 1.5 +5. Gastroesophageal reflux disease +6. Depression + + +Social History: +Works at [**Company 2475**] in office services. Lives with girlfriend in +[**Location (un) 686**]. Smokes approx 5 cigarettes/week. Usually rare EtOH, +except this past weekend. Denies illicit drug use. + + +Family History: +Mr. [**Known lastname 21822**] has 4 brothers and 5 sisters, all with no known Hx +of diabetes or significant medical problems. His [**Name2 (NI) **] are +alive and well. He reports that his grandfather had Diabetes, +but he isn??????t sure what type. + + +Physical Exam: +Temp 99.7 BP 149/87 HR 88 RR 20 O2 sat 99% +GEN: pt [**Name (NI) **]3, NAD, well nourished +HEENT: PERRLA +CV: RRR +Resp: CTAB no wheezes or crackles +Ab: +BS, soft, NT, ND +EXT: no edema, bruising, or cyanosis + + +Pertinent Results: +[**2142-10-22**] 08:59AM GLUCOSE-336* UREA N-51* CREAT-2.9* SODIUM-137 +POTASSIUM-4.6 CHLORIDE-97 TOTAL CO2-21* ANION GAP-24* + +[**2142-10-25**] 03:39AM BLOOD Glucose-59* UreaN-29* Creat-2.3* Na-140 +K-3.6 Cl-106 HCO3-24 AnGap-14 + +Brief Hospital Course: +29 M with DM1, DKA, hypertensive urgency likely secondary to +noncompliance. +. +DKA - likely [**2-9**] noncompliance. +- No evidence of infection as precipitant. CXR neg, UA with 0-2 +wbc, low grade fevers initially which have cleared, no increased +WBC + - CE x2 are nl + - gave fluids and insulin drip + - AG closed by HD 2 however pt continued to have some nausea + - HD 3 pt began taking PO, and was transitioned to [**1-9**] of his +home humalog dose + - HD 4 pt, had good PO intake, without nausea or vomiting +. +# Hypertensive Urgency - also likely [**2-9**] noncompliance, as pt +missed his am's dose of BP medications before admission. + - initially difficult to manage with IV metoprolol and +hydralazine + - Came under control to SBP of 150-170 range with 75 mg tid of +metoprolol and 10 mg of norvasc. + - will discharge on daily metoprolol and norvasc to increase +compliance + - pt likely to have baseline high blood pressures given history +of non-compliance + - Did not restart ACE-I due to worsening of renal function +. +# ARF - currently 2.3 down from Cr 2.9, with baseline ~2, likely +prerenal [**2-9**] DKA + - Gave IV hydration to assist with pre-renal causes, but Cr did +not return completely to baseline. + - Should follow up worsening renal function at [**Hospital **] clinic on +f/u apt as outpatient. +. +# FEN - Pt not tolerating PO's currently initially, but did +increase with time, IV fluid, and reglan. + - emesis initially treated with IV zofran and phenergan. + - pt transitioned to IV reglan and then PO reglan with good +results + - has reported history of gastroparesis and has been on reglan +before + - will give pt outpatient perscription for reglan to assist +with gastroparesis + - pt eating full meal at discharge + - continued home PPI +. +# Proph + - PPI + - pneumoboots and ambulation + - bowel regimen + +Medications on Admission: +NPH 40 u [**Hospital1 **] +lisinopril 5 mg po + +Discharge Medications: +1. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] DAILY (Daily). +2. Amlodipine 5 mg Tablet [**Last Name (STitle) **]: Two (2) Tablet PO DAILY (Daily). +Disp:*60 Tablet(s)* Refills:*2* +3. Metoclopramide 10 mg Tablet [**Last Name (STitle) **]: One (1) Tablet PO QIDACHS (4 +times a day (before meals and at bedtime)). +Disp:*120 Tablet(s)* Refills:*2* +4. Metoprolol Succinate 100 mg Tablet Sustained Release 24 hr +[**Last Name (STitle) **]: Two (2) Tablet Sustained Release 24 hr PO DAILY (Daily). +Disp:*60 Tablet Sustained Release 24 hr(s)* Refills:*2* +5. Insulin NPH Human Recomb 300 unit/3 mL Insulin Pen [**Last Name (STitle) **]: +Twenty (20) units Subcutaneous at bedtime. +Disp:*600 units* Refills:*2* +6. Insulin NPH Human Recomb 300 unit/3 mL Insulin Pen [**Last Name (STitle) **]: +Twenty (20) units Subcutaneous At breakfast. +Disp:*600 units* Refills:*2* +7. Regular insulin sliding scale +Please see attached regular insulin sliding scale. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary diagnosis: +# Diabetic ketoacidosis secondary to diabetes mellitus type 1 +# Gastroparesis secondary to diabetes mellitus type 1 +# Diabetes mellitus type 1 +# Hypertensive urgency +. +Secondary diagnosis: +# Chronic renal insufficiency secondary to diabetes mellitus +type 1 +# Diabetic neuropathy +# Gastroesophageal reflux disease +# Erosive gastritis +# Depression + +Discharge Condition: +Stable, tolerating PO intake. + +Discharge Instructions: +You were admitted to the intensive care unit because you were +hypoglycemic (had very low blood sugar) because of your type 1 +diabetes. We started you on an insulin trip. In addition, you +were nauseous and vomiting, probably related to gastroparesis +(slow intestinal movements) related to your type 1 diabetes, and +we gave you medications to help your intestines move. Finally, +we found that you had very high blood pressures, and we gave you +medications to lower your blood pressure. +. +We have started you on some new medications: +. +# For your nausea and vomiting: Metoclopramide 10 mg. Take one +tablet before meals and at bedtime every day. +. +# For your high blood pressure: +1. Toprol XL 200mg daily: Take 200 mg daily in the mornings. +2. Amlodipine 10mg daily: Take 10mg daily in the mornings. +. +# For your insulin: We have written a prescription for an +insulin pen for you to inject your NPH insulin. You should +inject 20 units NPH at every breakfast, and another 20 units NPH +at every bedtime. We have DECREASED your insulin dosage ONLY +BECAUSE YOU ARE NOT EATING A FULL DIET YET. Once you start +eating a full diet, you should return to using your 40 units NPH +at every breakfast, and another 40 units NPH at every bedtime. +. +We have ***STOPPED*** your lisinopril 5mg daily because of your +kidney function. Please follow up with the kidney doctor +mentioned below to determine whether you should restart it. +. +Otherwise, we have not changed your medications. +. +We have made several appointments for you. Please keep these +appointments. +. +If you experience nausea, vomiting, headache, changes in vision, +chest pain, fever, shortness of breath, or any other symptoms +you are concerned about, go immediately to the emergency room +and call your primary care doctor. + +Followup Instructions: +Because of your health, we strongly encourage you to follow up +with the doctors [**Name5 (PTitle) 7928**]. We have made the following appointments +for you: +. +[**Hospital 2793**] clinic (for your kidney): Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 4883**], tel. +[**Telephone/Fax (1) 60**], Wednesday, [**10-31**], at 8 am, Medical +Specialties [**Hospital Ward Name 23**] [**Location (un) **] +. +[**Hospital **] clinic (for your diabetes): Dr. [**First Name (STitle) **] [**Name (STitle) 9835**], tel. +[**Telephone/Fax (1) 2384**], Wednesday, [**10-31**], at 1pm, [**Last Name (un) **] Diabetes +Center, [**Location (un) **]. Please check in at front desk. +. +Primary care (for your overall health): Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], tel. +[**Telephone/Fax (1) 250**], Wednesday, [**11-7**], at 1:30 pm, [**Location (un) 3387**], Central 6, [**Hospital Ward Name 23**] Building. +. +Please call if there are any conflicts with your schedule. + + +",165,2142-10-22 11:09:00,2142-10-25 14:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,DIABETIC KETOACIDOSIS," +29 m with dm1, dka, hypertensive urgency likely secondary to +noncompliance. +. +dka - likely [**2-9**] noncompliance. +- no evidence of infection as precipitant. cxr neg, ua with 0-2 +wbc, low grade fevers initially which have cleared, no increased +wbc + - ce x2 are nl + - gave fluids and insulin drip + - ag closed by hd 2 however pt continued to have some nausea + - hd 3 pt began taking po, and was transitioned to [**1-9**] of his +home humalog dose + - hd 4 pt, had good po intake, without nausea or vomiting +. +# hypertensive urgency - also likely [**2-9**] noncompliance, as pt +missed his ams dose of bp medications before admission. + - initially difficult to manage with iv metoprolol and +hydralazine + - came under control to sbp of 150-170 range with 75 mg tid of +metoprolol and 10 mg of norvasc. + - will discharge on daily metoprolol and norvasc to increase +compliance + - pt likely to have baseline high blood pressures given history +of non-compliance + - did not restart ace-i due to worsening of renal function +. +# arf - currently 2.3 down from cr 2.9, with baseline ~2, likely +prerenal [**2-9**] dka + - gave iv hydration to assist with pre-renal causes, but cr did +not return completely to baseline. + - should follow up worsening renal function at [**hospital **] clinic on +f/u apt as outpatient. +. +# fen - pt not tolerating pos currently initially, but did +increase with time, iv fluid, and reglan. + - emesis initially treated with iv zofran and phenergan. + - pt transitioned to iv reglan and then po reglan with good +results + - has reported history of gastroparesis and has been on reglan +before + - will give pt outpatient perscription for reglan to assist +with gastroparesis + - pt eating full meal at discharge + - continued home ppi +. +# proph + - ppi + - pneumoboots and ambulation + - bowel regimen + + ","PRIMARY: [Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage I through stage IV, or unspecified] +SECONDARY: [Diabetes with ketoacidosis, type I [juvenile type], uncontrolled; Acute kidney failure, unspecified; Chronic kidney disease, unspecified; Gastroparesis; Personal history of noncompliance with medical treatment, presenting hazards to health; Polyneuropathy in diabetes; Other specified gastritis, without mention of hemorrhage; Esophageal reflux; Depressive disorder, not elsewhere classified; Alcohol abuse, unspecified; Diabetes with neurological manifestations, type I [juvenile type], uncontrolled; Diabetes with renal manifestations, type I [juvenile type], uncontrolled]" +23657,176997.0,13519,2145-04-18,13518,169263.0,2145-03-24,Discharge summary,"Admission Date: [**2145-3-21**] Discharge Date: [**2145-3-24**] + +Date of Birth: [**2112-11-14**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Watermelon / Almond Oil + +Attending:[**First Name3 (LF) 783**] +Chief Complaint: +Shortness of breath, nausea, vomiting + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +32 y/o M with hx of DM I, HTN, ESRD on HD (last HD yesterday +with uneventful full run). Today had sudden onset SOB when he +woke up. Felt positional and was improved with sitting up and +worsened with lying down. Also then had symptoms with diarrhea +and vomiting a few hours after waking up. They were +non-bilious, non-bloody emesis and diarrhea. His SOB continued +and he felt as if he had a tight feeling in his chest. Also +felt some tightness substernally. No fevers, chills. Did have +some sweats recently, but had otherwise been feeling well and +healthy since his last discharge for n/v and gastroparesis. +. +In the ED, initial vitals were T 100.4, 203/116, 114 NSR, 40, +85% RA. Overall, mildly uncomfortable and working to breath, +rales bilaterally. Had soft, distended, non-tender abdomen. +Refused guiac exam. He received vanco, zosyn, and levo for +potential pna. Also received an ASA. Started on nitro gtt for +hypertension. Renal aware of patient and that he received +contrast for his CTA. +. +On transfer from the ED, his vitals were 181/107, 124, 25, 97% +NRB (was 90 on 6L). He was mildly uncomfortable. He is +complaining of shortness of breath and a headache. His nausea +is mostly improved. He otherwise is comfortable on 6L NC. +. +In the MICU, he had CTA which was negative for PE and consistent +with pulmonary edema so antibiotics were discontinued. He +received a one time dose of lasix 20 IV with good UOP and BP +improved on home regimen as he was weaned off nitro drip and +down to 2L O2 by NC. At time of transfer, he reports SOB much +improved and denies any current CP. + +Past Medical History: +- HTN +- DM I since age 19, seen at [**Last Name (un) **]. Complicated by nephropathy, +gastroparesis, and possibly retinopathy. +- CKD: thought to be related to HTN and longstanding diabetes. +Now on hemodialysis T/Th/Sat. Does make urine. Has been listed +on kidney/pancreas transplant wait list since 4/[**2144**]. +- Anemia: Thought to be combination of iron deficiency and CKD, +now on epo with dialysis +- Depression +- s/p appendectomy [**7-/2144**] + +Social History: +States that he previously drank heavily (30-40 drinks/week) but +has not used alcohol since [**2144-11-14**]. +h/o tobacco use, quit in +[**2142**], relapsed, quit last year and denies tobacco currently. +Denies other drugs. Neg PPD [**2145-2-26**]. Lives with girlfriend. + +Family History: +No FH of pancreatitis. Diabetes and heart trouble in +grandfather. + +Physical Exam: +General Appearance: Well nourished +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Cardiovascular: (S1: Normal), (S2: Normal), no rubs +Peripheral Vascular: (Right radial pulse: Present), (Left radial +pulse: Present), (Right DP pulse: Present), (Left DP pulse: +Present) +Respiratory / Chest: (Expansion: Symmetric), (Breath Sounds: +Clear : , Crackles : few at bilateral bases) +Abdominal: Soft, Non-tender, Bowel sounds present +Extremities: Right lower extremity edema: Trace, Left lower +extremity edema: Absent +Skin: Not assessed +Neurologic: Attentive, Responds to: Not assessed, Movement: Not +assessed, Tone: Not assessed + + +Pertinent Results: +[**2145-3-21**] 07:00PM BLOOD WBC-8.1 RBC-3.05* Hgb-8.4* Hct-27.1* +MCV-89 MCH-27.5 MCHC-31.0 RDW-15.3 Plt Ct-275 +[**2145-3-22**] 04:02AM BLOOD WBC-9.3 RBC-2.64* Hgb-7.4* Hct-23.7* +MCV-90 MCH-28.1 MCHC-31.3 RDW-15.4 Plt Ct-282 +[**2145-3-23**] 07:20AM BLOOD WBC-10.4 RBC-2.74* Hgb-8.1* Hct-24.7* +MCV-90 MCH-29.3 MCHC-32.6 RDW-15.8* Plt Ct-312 +[**2145-3-24**] 06:03AM BLOOD WBC-5.1# RBC-2.65* Hgb-7.9* Hct-24.1* +MCV-91 MCH-29.8 MCHC-32.8 RDW-15.6* Plt Ct-252 +[**2145-3-21**] 07:00PM BLOOD Neuts-86.7* Lymphs-9.3* Monos-3.7 Eos-0.3 +Baso-0.1 +[**2145-3-22**] 04:02AM BLOOD PT-11.8 PTT-26.0 INR(PT)-1.0 +[**2145-3-21**] 07:00PM BLOOD Glucose-214* UreaN-23* Creat-6.4*# Na-137 +K-5.5* Cl-99 HCO3-30 AnGap-14 +[**2145-3-22**] 04:02AM BLOOD Glucose-91 UreaN-27* Creat-7.3* Na-138 +K-4.6 Cl-101 HCO3-30 AnGap-12 +[**2145-3-23**] 07:20AM BLOOD Glucose-127* UreaN-36* Creat-9.3*# Na-135 +K-6.1* Cl-97 HCO3-26 AnGap-18 +[**2145-3-24**] 06:03AM BLOOD Glucose-177* UreaN-26* Creat-7.0*# Na-134 +K-4.9 Cl-95* HCO3-31 AnGap-13 +[**2145-3-21**] 07:00PM BLOOD ALT-77* AST-71* AlkPhos-93 TotBili-0.3 +[**2145-3-22**] 04:02AM BLOOD ALT-57* AST-39 CK(CPK)-261 AlkPhos-80 +TotBili-0.3 +[**2145-3-23**] 07:20AM BLOOD ALT-44* AST-25 AlkPhos-90 TotBili-0.4 +[**2145-3-24**] 06:03AM BLOOD ALT-33 AST-21 AlkPhos-78 TotBili-0.2 +[**2145-3-21**] 07:00PM BLOOD Lipase-177* +[**2145-3-21**] 07:00PM BLOOD proBNP-[**Numeric Identifier 40887**]* +[**2145-3-21**] 07:00PM BLOOD cTropnT-0.10* +[**2145-3-22**] 04:02AM BLOOD CK-MB-2 cTropnT-0.12* +[**2145-3-22**] 12:10PM BLOOD CK-MB-2 cTropnT-0.12* +[**2145-3-22**] 04:02AM BLOOD Calcium-8.6 Phos-2.2*# Mg-1.6 +[**2145-3-23**] 07:20AM BLOOD Calcium-8.6 Phos-2.5* Mg-1.7 +[**2145-3-24**] 06:03AM BLOOD Calcium-8.3* Phos-4.5# Mg-1.6 +[**2145-3-21**] 7:00 pm BLOOD CULTURE LINE EJ: Pending at +discharge. + URINE CULTURE (Final [**2145-3-23**]): NO GROWTH. + Legionella Urinary Antigen (Final [**2145-3-22**]): + NEGATIVE FOR LEGIONELLA SEROGROUP 1 ANTIGEN. +-- +Radiology Report CHEST (PORTABLE AP) Study Date of [**2145-3-21**] +Final Report +EXAM: Chest frontal, single AP upright portable view. +Large areas of airspace opacity involving the right mid-to-lower +lung, likely involving the right middle and lower lobes and +possibly the right upper lobe. There is suggestion of small +bilateral pleural effusions. The cardiac silhouette remains +enlarged. +IMPRESSION: +1. Right lung airspace opacity concerning for infectious process +vs edema. Recommend clinical correlation and followup to +resolution. Small bilateral pleural effusions. +2. Persistent moderate cardiomegaly. +--- +Radiology Report CTA CHEST W&W/O C&RECONS, NON-CORONARY Study +Date of [**2145-3-21**] Final Report +CHEST CT WITH IV CONTRAST: The thoracic aorta is normal in +course and +caliber, without dissection. The pulmonary arteries opacify +normally, without evidence of pulmonary embolism. The main +pulmonary artery is enlarged, measuring 3.6 cm in diameter. +Mediastinal and hilar lymph nodes do not meet size criteria for +pathologic enlargement. There are extensive nodular opacities +involving all lobes of the lungs, mid lung and basal +predominant. More confluent areas of airspace consolidation are +present centrally and dependently. There is interlobular septal +thickening, left greater than right. The airways are patent +bilaterally to the subsegmental level. There is a small right +pleural effusion and a moderate pericardial effusion. The heart +is enlarged. Enlarged prevascular and pretracheal mediastinal +lymph nodes are likely reactive. Anterior mediastinal soft +tissue density is likely residual thymus. + +Imaging of the upper abdomen is unremarkable. There are no +concerning osseous lesions. + +IMPRESSION: +1. No pulmonary embolism. No aortic dissection. +2. Extensive nodular opacities throughout all lobes concerning +for infection. Confluent areas of airspace opacity may reflect +pulmonary edema or infection. Septal thickening consistent with +interstitial pulmonary edema. Mediastinal lymphadenopathy, may +be reactive. +3. Moderate pericardial effusion. +4. Small right pleural effusion. +5. Enlarged main pulmonary artery suggestive of pulmonary +arterial +hypertension. +--- +Portable TTE (Complete) Done [**2145-3-22**] at 9:30:00 AM FINAL + +Findings +This study was compared to the prior study of [**2144-2-14**]. +Multiplanar reconstructions were generated and confirmed on an +independent workstation. + +LEFT ATRIUM: Mild LA enlargement. + +LEFT VENTRICLE: Mild symmetric LVH with normal cavity size. Low +normal LVEF. Estimated cardiac index is normal (>=2.5L/min/m2). +No resting LVOT gradient. + +RIGHT VENTRICLE: Normal RV chamber size and free wall motion. + +AORTA: Mildly dilated aortic sinus. Mildly dilated ascending +aorta. No 2D or Doppler evidence of distal arch coarctation. + +AORTIC VALVE: Normal aortic valve leaflets (3). No AS. Trace AR. + + +MITRAL VALVE: Normal mitral valve leaflets with trivial MR. + +TRICUSPID VALVE: Normal tricuspid valve leaflets with trivial +TR. Moderate PA systolic hypertension. + +PULMONIC VALVE/PULMONARY ARTERY: Normal pulmonic valve leaflet. +No PS. Physiologic PR. + +PERICARDIUM: Small to moderate pericardial effusion. Effusion +circumferential. No echocardiographic signs of tamponade. +Echocardiographic signs of tamponade may be absent in the +presence of elevated right sided pressures. + +Conclusions +The left atrium is mildly dilated. There is mild symmetric left +ventricular hypertrophy with normal cavity size. Overall left +ventricular systolic function is low normal. Quantitative +biplane LVEF is 52%. The estimated cardiac index is normal +(>=2.5L/min/m2). Right ventricular chamber size and free wall +motion are normal. The aortic root is mildly dilated at the +sinus level. The ascending aorta is mildly dilated. The aortic +valve leaflets (3) appear structurally normal with good leaflet +excursion and no aortic stenosis. Trace aortic regurgitation is +seen. The mitral valve appears structurally normal with trivial +mitral regurgitation. There is moderate pulmonary artery +systolic hypertension. There is a small to moderate sized +circumferential pericardial effusion without echocardiographic +signs of tamponade. Echocardiographic signs of tamponade may be +absent in the presence of elevated right sided pressures. + +IMPRESSION: Mild symmetric left ventricular hypertrophy with low +normal systolic function. Moderate pulmonary artery systolic +hypertension. Small-moderate circumferential pericardial +effusion. +Compared with the prior study (images reviewed) of [**2144-2-14**], +left ventricular systolic function is less vigorous and +pulmonary artery systolic hypertension is now identified. + +CLINICAL IMPLICATIONS: +Based on [**2142**] AHA endocarditis prophylaxis recommendations, the +echo findings indicate prophylaxis is NOT recommended. Clinical +decisions regarding the need for prophylaxis should be based on +clinical and echocardiographic data. +--- +Radiology Report CHEST (PORTABLE AP) Study Date of [**2145-3-22**] +Final Report +PORTABLE CHEST +FINDINGS: Previously identified asymmetrically distributed +opacities in the right lung have rapidly improved with only +minimal residual opacities, +predominantly in the right retrocardiac region. However, opacity +in the left retrocardiac area has slightly worsened. Small +pleural effusions are again demonstrated. Cardiac silhouette +remains enlarged and there is persistent increase in pulmonary +vascularity. + +IMPRESSION: +1. Rapid improvement in right-sided alveolar opacities, which +may have been due to asymmetrical pulmonary edema or aspiration +considering the rapid improvement. Worsening opacities at left +base could reflect evolving +infection in the appropriate clinical setting. +2. Enlarged cardiac silhouette with known pericardial effusion. +3. Small bilateral pleural effusions. +-- +Radiology Report CHEST (PA & LAT) Study Date of [**2145-3-23**] +Final Report +IMPRESSION: PA and lateral chest compared to [**3-22**]: +Severe cardiomegaly is stable. Small left pleural effusion is +new or newly +apparent. Pulmonary vascular congestion is mild though the upper +lobe vessels are clearly dilated and there is no pulmonary +edema. +-- + + +Brief Hospital Course: +32yom w T1DM, ESRD on hemodialysis, HTN presented with sudden +onset dyspnea, likely due to flash pulmonary edema in setting of +severe hypertension. + +# Shortness of breath: Presented w sudden onset dyspnea. Most +likely due to flash pulmonary edema given severe HTN on +presentation, elevated BNP, CXR and CTA showing pulmonary edema +which rapidly resolved with blood pressure control. Echo showed +new findings of mild LV systolic dysfunction (EF 52%), moderate +pulmonary artery HTN, and small-moderate circumferential +pericardial effusion (previously seen on CT abd [**2145-3-6**]). +Troponins cycled every 8 hours were 0.10, 0.12, 0.12, consistent +with demand ischemia in setting of renal failure without concern +for an acute ischemic event. EKG on admission was unchanged from +prior. CTA was negative for PE. Initially, CXR had infiltrate +concerning for PNA, so pt was started on antibiotics for +hospital acquired PNA. However, these were discontinued after +rapid improvement of CXR with diuresis. In the MICU, pt was +treated with a nitro drip, lasix (with good urine output), and +supplmental O2 via nasal cannula. On transfer to the floor, +lungs were wheezy and pt sated 91%-95% on 2-4L NC. After +hemodialysis, lungs were clear, and pt sated 95-100% on room +air. Although patient had low grade temperatures (99.0), he did +not develop localizing symptoms or leukocytosis concerning for +health care acquired pneumonia. Given good urine output despite +being on hemodialysis, patient was started on 80mg daily of +Lasix PO by Renal upon discharge. +. +# Hypertension: SBP in 200s on arrival in setting of medication +noncompliance secondary to PO intolerance. Placed on nitro drip +until tolerating POs, at which point home antihypertensives +(hydralazine, lisinopril, metoprolol) were restarted. SBP ranged +120s-170s on floor with some improvement after dialysis as well. + +. +# End stage renal failure: Renal followed patient, and he was +able to remain on his regular T/Th/Sat dialysis schedule while +in house. +. +# Nausea/Vomiting: Etiology for nausea and vomiting unclear, +although likely from gastroparesis as noted in previous +admissions. Was given zofran and reglan PRN with good control of +symptoms. +. +# Pulmonary Hypertension: Increased PASP new since last TTE and +slightly decreased LVEF compared with 2/09 as well as BNP [**Numeric Identifier 14123**] +all suggest left heart failure as etiology of pulmonary +hypertension. Patient should consider further work-up as +outpatient (rheum, LFTs, HIV, right heart cath...) +. +# Pericardial Effusion: likely secondary to renal failure. +Unchanged based on findings on CT scan. Pulsus < 10 without +signs of tamponade. +. +# Anemia: On transfer to MICU, Hct was 27, which was above +baseline of 23. Thought to be secondary to volume contraction in +the setting of nause and vomiting. With improvement of +nausea/vomiting his hematocrit trended back to his baseline of +23. No clinical evidence of bleeding during his stay. +. +# Transaminitis: On admission, mildly elevated AST and ALT in +70s. Alk phos was normal. Unclear etiology, but perhaps +secondary to hepatic congestion in setting of flash pulmonary +edema. Had normal ultrasound last admission. Liver function +tests were trended and came down with improvement in his +clinical status. +. +# Type I Diabetes: Complicated by nephropathy, neuropathy and +gastroparesis. Remained on insulin sliding scale and home lantus +dose. Blood sugar ranged from 161-204. No anion gap on routine +labs to suggest ketoacidosis. + +Medications on Admission: +# Hydralazine 25 mg tabs, 1-2 tabs TID +# Amlodipine 10 mg daily +# Calcium Acetate 667 mg TID +# Vitamin D 5,000 units daily +# Calcitriol 0.25 mcg daily +# Metoclopramide 5 mg TID PRN +# Lisinopril 20 mg daily +# Metoprolol Succinate 200 mg Tablet Sustained Release daily +# EMLA 2.5-2.5 % Cream [**Hospital1 **] +# Humalog Sliding Scale +# Glargine 15 u qHS + +Discharge Medications: +1. Hydralazine 25 mg Tablet [**Hospital1 **]: One (1) Tablet PO TID (3 times +a day). +Disp:*90 Tablet(s)* Refills:*2* +2. Lisinopril 20 mg Tablet [**Hospital1 **]: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +3. Calcium Acetate 667 mg Capsule [**Hospital1 **]: Two (2) Capsule PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +4. Metoclopramide 10 mg Tablet [**Hospital1 **]: 0.5 Tablet PO TID (3 times a +day): Do not take when you have loose stools, diarrhea. +5. Vitamin D 5,000 unit Tablet [**Hospital1 **]: One (1) Tablet PO once a day +for 2 weeks. +6. Ergocalciferol (Vitamin D2) 50,000 unit Capsule [**Hospital1 **]: One (1) +Capsule PO once a week: Mondays. +7. Calcitriol 0.25 mcg Capsule [**Hospital1 **]: One (1) Capsule PO once a +day. +8. Amlodipine 10 mg Tablet [**Hospital1 **]: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* +9. Metoprolol Succinate 200 mg Tablet Sustained Release 24 hr +[**Hospital1 **]: One (1) Tablet Sustained Release 24 hr PO once a day. +Disp:*30 Tablet Sustained Release 24 hr(s)* Refills:*2* +10. Lasix 80 mg Tablet [**Hospital1 **]: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* +11. Insulin Glargine 100 unit/mL Solution [**Hospital1 **]: Fifteen (15) +units Subcutaneous with breakfast. +12. Humalog 100 unit/mL Solution [**Hospital1 **]: per sliding scale +Subcutaneous four times a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: Flash pulmonary edema with hypertensive urgency +Secondary: ESRD on hemodialysis, type 1 diabetes mellitus, +gastroparesis, anemia + + +Discharge Condition: +Mental Status: Clear and coherent +Level of Consciousness: Alert and interactive +Activity Status: Ambulatory - Independent + + +Discharge Instructions: +-You were admitted with acute shortness of breath, nausea and +vomiting. You likely had an episode of ""flash pulmonary edema,"" +or rapid fluid buildup in the lungs, due to high blood pressures +(perhaps from high sodium/salt meal). Your blood pressure was +aggressively controlled; fluid in your lungs was removed by +hemodialysis and a water pill (Lasix) with improvement in your +breathing. +. +-It is important that you continue to take your medications as +directed. We made the following changes to your medications +during this admission: +--> Start Lasix 80mg daily +. +-Contact your doctor or come to the Emergency Room should your +symptoms return. Also seek medical attention if you develop any +new fever, chills, trouble breathing, chest pain, nausea, +vomiting or unusual stools. + +Followup Instructions: +Please make an appointment to see your primary care doctor +within 2 weeks. You can reach Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) 40888**] office at +[**Telephone/Fax (1) 250**]. +. +Department: [**Hospital3 249**] +When: WEDNESDAY [**2145-3-24**] at 12:00 PM +With: [**First Name8 (NamePattern2) 971**] [**Last Name (NamePattern1) **], LICSW [**Telephone/Fax (1) 250**] +Building: SC [**Hospital Ward Name 23**] Clinical Ctr [**Location (un) 895**] +Campus: EAST Best Parking: [**Hospital Ward Name 23**] Garage + +Department: TRANSPLANT +When: MONDAY [**2145-4-12**] at 1 PM +With: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 2088**], MD [**Telephone/Fax (1) 673**] +Building: LM [**Hospital Unit Name **] [**Location (un) **] +Campus: WEST Best Parking: [**Hospital Ward Name **] Garage + +Department: CARDIAC SERVICES +When: FRIDAY [**2145-4-16**] at 3:00 PM +With: [**Year (4 digits) **] [**Telephone/Fax (1) 62**] +Building: SC [**Hospital Ward Name 23**] Clinical Ctr [**Location (un) **] +Campus: EAST Best Parking: [**Hospital Ward Name 23**] Garage + + + [**First Name11 (Name Pattern1) 734**] [**Last Name (NamePattern1) 735**] MD, [**MD Number(3) 799**] + +",25,2145-03-21 21:13:00,2145-03-24 11:14:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,SHORTNESS OF BREATH," +32yom w t1dm, esrd on hemodialysis, htn presented with sudden +onset dyspnea, likely due to flash pulmonary edema in setting of +severe hypertension. + +# shortness of breath: presented w sudden onset dyspnea. most +likely due to flash pulmonary edema given severe htn on +presentation, elevated bnp, cxr and cta showing pulmonary edema +which rapidly resolved with blood pressure control. echo showed +new findings of mild lv systolic dysfunction (ef 52%), moderate +pulmonary artery htn, and small-moderate circumferential +pericardial effusion (previously seen on ct abd [**2145-3-6**]). +troponins cycled every 8 hours were 0.10, 0.12, 0.12, consistent +with demand ischemia in setting of renal failure without concern +for an acute ischemic event. ekg on admission was unchanged from +prior. cta was negative for pe. initially, cxr had infiltrate +concerning for pna, so pt was started on antibiotics for +hospital acquired pna. however, these were discontinued after +rapid improvement of cxr with diuresis. in the micu, pt was +treated with a nitro drip, lasix (with good urine output), and +supplmental o2 via nasal cannula. on transfer to the floor, +lungs were wheezy and pt sated 91%-95% on 2-4l nc. after +hemodialysis, lungs were clear, and pt sated 95-100% on room +air. although patient had low grade temperatures (99.0), he did +not develop localizing symptoms or leukocytosis concerning for +health care acquired pneumonia. given good urine output despite +being on hemodialysis, patient was started on 80mg daily of +lasix po by renal upon discharge. +. +# hypertension: sbp in 200s on arrival in setting of medication +noncompliance secondary to po intolerance. placed on nitro drip +until tolerating pos, at which point home antihypertensives +(hydralazine, lisinopril, metoprolol) were restarted. sbp ranged +120s-170s on floor with some improvement after dialysis as well. + +. +# end stage renal failure: renal followed patient, and he was +able to remain on his regular t/th/sat dialysis schedule while +in house. +. +# nausea/vomiting: etiology for nausea and vomiting unclear, +although likely from gastroparesis as noted in previous +admissions. was given zofran and reglan prn with good control of +symptoms. +. +# pulmonary hypertension: increased pasp new since last tte and +slightly decreased lvef compared with 2/09 as well as bnp [**numeric identifier 14123**] +all suggest left heart failure as etiology of pulmonary +hypertension. patient should consider further work-up as +outpatient (rheum, lfts, hiv, right heart cath...) +. +# pericardial effusion: likely secondary to renal failure. +unchanged based on findings on ct scan. pulsus < 10 without +signs of tamponade. +. +# anemia: on transfer to micu, hct was 27, which was above +baseline of 23. thought to be secondary to volume contraction in +the setting of nause and vomiting. with improvement of +nausea/vomiting his hematocrit trended back to his baseline of +23. no clinical evidence of bleeding during his stay. +. +# transaminitis: on admission, mildly elevated ast and alt in +70s. alk phos was normal. unclear etiology, but perhaps +secondary to hepatic congestion in setting of flash pulmonary +edema. had normal ultrasound last admission. liver function +tests were trended and came down with improvement in his +clinical status. +. +# type i diabetes: complicated by nephropathy, neuropathy and +gastroparesis. remained on insulin sliding scale and home lantus +dose. blood sugar ranged from 161-204. no anion gap on routine +labs to suggest ketoacidosis. + + ","PRIMARY: [Acute diastolic heart failure] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Unspecified disease of pericardium; Diabetes with renal manifestations, type I [juvenile type], not stated as uncontrolled; Other chronic pulmonary heart diseases; Diabetes with ophthalmic manifestations, type I [juvenile type], not stated as uncontrolled; Congestive heart failure, unspecified; Diabetes with neurological manifestations, type I [juvenile type], not stated as uncontrolled; Hyperpotassemia; Renal dialysis status; Background diabetic retinopathy; Gastroparesis; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Long-term (current) use of insulin; Anemia in chronic kidney disease; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]; Other postprocedural status]" +23657,176997.0,13519,2145-04-18,13517,125544.0,2145-02-27,Discharge summary,"Admission Date: [**2145-2-18**] Discharge Date: [**2145-2-27**] + +Date of Birth: [**2112-11-14**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Watermelon / Almond Oil + +Attending:[**First Name3 (LF) 9454**] +Chief Complaint: +Nausea/vomiting, diarrhea --> DKA + +Major Surgical or Invasive Procedure: +PICC line placement +Initiation of hemodialysis + +History of Present Illness: +Mr. [**Known lastname 21822**] is a 32 year-old man with a history of HTN, type 1 +diabetes with gastroparesis, CKD stage V and recently s/p AV +fistula [**2145-1-22**] in anticipation of HD, and anemia who presents +with profuse watery vomiting and watery diarrhea for last 2 +days. No blood or mucus. No fevers but did have night sweats and +chills. He also has crampy abdominal pain improved with bowel +movements. He has only been able to keep down sips. He denies +any lightheadedness. He does still make urine and has not noted +any change in UOP, dysuria, or hematuria. He denies any sick +contacts but did just return to work yesterday after recovering +from placement of a RUE graft on [**1-26**]. He denies any recent +travel or antibiotics use. He states his BS have been in 100s +and he has been taking his lantus 15 in AM, but states this is +what his DKA has felt like in the past. + + +Past Medical History: +- HTN +- DM I since age 19, seen at [**Last Name (un) **]. Complicated by nephropathy, +gastroparesis, proteinuria and possibly retinopathy. +-CKD: thought to be related to HTN and longstanding DMII. +Underwent RUE fistula placement on [**1-26**] for planned HD +initiation. Being considered for liver-pancreas transplant +- Anemia: Thought to be combination of iron deficiency and CKD, +still taking iron +- Depression +- S/p appendectomy [**7-/2144**] + +Social History: +Lives with his girlfriend. [**Name (NI) 1403**] in a clerical setting. Quit +smoking 2 days ago, 5 pk year history. Occasional ETOH. No +illicit drugs. + + +Family History: +Diabetes and heart trouble in grandfather + +Physical Exam: +Physical Exam (on Admission) +Vitals: T 99.2, HR 100, BP 171/90, RR 12, O2sat 97RA. +General: Uncomfortable appearing young man, recently vomited +small amount of nonbloody nonbilous emesis +HEENT: NCAT, MMM, oropharynx clear +Neck: Supple, LAD +Pulm: CTA B +CV: Tachycardic but regular, promienent P2, no m/r/g +Abd: BS hyperactive but not high-pitched, diffuse tenderness +without guarding or rebound, nondistended +Extrem: No LE edema, DP pulses 2+ +Neuro: AAOx 3, grossly nonfocal, no asterixis +Derm: No rash + +Pertinent Results: +On admission to MICU: +pH 7.27 pCO2 24 pO2 233 HCO3 12 BaseXS -13 +140 107 100 AGap=26 +-------------<305 +5.1 12 15.2 +Ca: 8.3 Mg: 2.0 P: 8.0 +ALT: 62 AP: 77 Tbili: 0.1 +AST: 33 [**Doctor First Name **]: 93 Lip: 59 +Osms:346 +Serum Acetmnphn Negative +MCV 88 +wbc 8.2 +plts 272 +hct 20.0 +N:87.2 L:8.7 M:3.1 E:0.8 Bas:0.1 +Lactate: 0.8 + +EKG: NSR at 97 bpm, nl axis and intervals, no ST-T wave changes + + +Chem ([**2-27**]): 140/4.1 101/29 31/8.7 < 70 Ca=8.0 Mg=1.8 +P=4.1 +CBC ([**2-27**]): 6.4 > 22.1 < 233 + +Blood culture [**2-24**] and [**2-27**]: Final read negative + + +Brief Hospital Course: +In the ER on [**2-18**], his vitals were: T 100.1, P 98, BP 164/90, RR +16, O2 sat 100%. He had abdominal pain, and he was guiac +negative. His initial creatinine was 15.3, his glucose was 162, +and he had a metabolic acidosis with an anion gap of 24 (up from +his baseline of 19, due to his chronic kidney disease). He was +given 2L IVF for hydration, and his anion gap closed to 20. He +was given morphine 4 mg IV x 2 and zofran 4 mg IV x 2, and +admitted to medicine. On transfer to the floor his vitals were: +T 99.2, HR 100, BP 171/90, RR 12, O2sat 97% on room air. +. +On the medicine floor he had worsening nausea, vomiting and +abdominal pain, his glucose rose to 305, his gap increased to 21 +and his pH was 7.27. He received another 2 liters of normal +saline, but become tachypneic. His tachypnea resolved with +diuresis (Lasix 20 mg IV). On [**2-19**] the patient was transferred +to the MICU for an insulin drip and management of DKA. He +received 2 liters of D5W in normal saline, then 1 liter of D5W +with 3 amps of bicarb, then 1 liter of D5W with K+. For his +hematocrit of 20 he received 1 unit of pRBCs. His gap was back +down to 21 by 23:00 that evening. + +On [**2-20**] the patient had his first session of hemodialysis. He +declined his renal diet all day, then at midnight had [**State 19827**] +Fried Chicken brought in from outside. In the early AM of [**2-21**] +he developed nausea, vomiting, a glucose of 436 and DKA. He had +an EKG that showed no ischemia, and morphine for pain. For +systolic blood pressures from 190-210 he received IV doses of +his home PO antihypertensives (Hydralazine and Metoprolol). The +patient was refusing his calcium capsules because they were too +big to swallow, and tried to order a pizza in instead of +hospital food. + +By [**2-24**] he had been transitioned from insulin drip to insulin +boluses. On [**2-25**] he had his 4th session of dialysis. He wanted +to leave that evening AMA (felt he had lost his freedom), but +was convinced to stay. On [**2-26**] he again wanted to leave AMA but +was again convinced to stay one more day for a 5th dialysis +session and to arrange optimal outpatient followup. He was +transferred out of the ICU to the medicine floor. + +Overnight on [**3-31**], he [**Date Range 28316**] a fever to 100.9. Blood +cultures were sent and he underwent his 5th dialysis session. +Following his HD session, he was seen by the medical team and +advised to stay in the hospital for one more day to assess for +an infection, given his overnight fever and recent initiation of +hemodialysis. He was advised to stay to ensure he remained +afebrile for 24 hours. Mr. [**Known lastname 21822**] refused this advise and +decided to sign out AGAINST MEDICAL ADVICE, despite repeated +discussions with him regarding our decision and desire to +monitor him for another day. + +By problem: +Anion gap metabolic acidosis/hyperglycemia/DKA. Increased above +baseline on presentation probably due to uremia in setting of +dehydration. It slightly improved s/p 2L IVF near baseline gap +of 19. But after brief stay on the regular medicine floor, his +blood sugar elevated into the 200-300s and anion gap increased; +acetone found in serum and ketones seen in urinalysis, +concerning for DKA. Lactate was normal. In the MICU, patient was +started on an insulin gtt and started on intravenous fluids. In +total, patient received 2L D51/2NS, then D5W with 3 amps bicarb +in 1L, then D5W with potassium. He had a PICC placed for regular +(every 4 hour) electrolyte checks. Patient's anion gap decreased +to baseline ~17, given patient's underlying end-stage renal +disease/uremia. Insulin gtt was discontinued and [**First Name8 (NamePattern2) **] [**Last Name (un) **] +recs, patient was started on a fixed Lantus and Humalog sliding +scale. Of note, on [**2-20**], patient refused hospital diet +and had his girlfriend bring him [**State 19827**] Fried Chicken; his +blood sugars and anion gap increased. Patient required +resumption of insulin gtt briefly; he was resumed on insulin +sliding scale and fixed dose, with Nutrition Consult and Social +Work following for coping/management of his long-standing, +complicated Type 1 Diabetes Mellitus. + +N/V/D, abdominal pain. Given low grade fever and acute onset, +most c/w viral gastroenteritis although possible that this was +exacerbated by uremia. Also, patient has a hx of gastroparesis. +Abdominal exam nonfocal but with tenderness initially that +resolved. Did have an episode of resumed, increased abdominal +pain after consumption of KFC, likely due to brief opening of +anion gap and underlying gastroparesis. Lipase was normal. Mild +elevation of LFTs gradually resolved. Pt did not appear fluid +overloaded on exam. Patient's diarrhea resolved while in MICU +and as per above, developed appetite and was able to tolerate PO +medications/diet. Clostridium difficile toxin was sent and +negative + +Acute on chronic renal failure. Pt was already in end stage +renal disease (stage 4) on admission. AV fisulta had been +recently placed for initiation of hemodialysis. In the setting +of profuse nausea, vomiting and diarrhea, there was also likely +a prerenal component to the bump in creatinine. Patient received +2L intravenous fluids in the ED and then approximately 4L to +manage his DKA. Patient did become hypertensive likely in this +setting. Patient was continued on calcitriol, calcium acetate, +and nephrotoxic medications were avoided. Renal followed the +patient during this admission and initiated hemodialysis with +good effect on his creatinine and volume status. + +Anemia. Initially on arrival to the MICU, hematocrit was 20, +mildly below baseline of 25 and felt due to the combination of +iron deficiency and CKD. Patient did not have emesis or blood in +his stools. Patient was transfused one unit of pRBC with good +effect. He was continued on iron supplements and may benefit +from Epogen with hemodialysis in the future. + +HTN. Poorly controlled, likely in the setting of initial acute +discomfort and later due to volume overload in the setting of +his ESRD and intravenous fluids for DKA. Patient was ultimately +transitioned to a regimen of Metoprolol 100mg twice daily, +Amlodipine 10mg daily and Hydralazine 50mg three times daily. + +Fever. Mr. [**Known lastname 21822**] [**Last Name (Titles) 28316**] a fever to 100.9 on the night of +[**3-31**]. As discussed above, in the setting of recent +initiation of hemodialysis and pending blood cultures, the +patient was advised to remain in the hospital to be sure he was +afebrile for 24 hours, without signs or symptoms of infection, +and that his blood cultures remained negative. Mr. [**Known lastname 21822**] +refused, and signed out AGAINST MEDICAL ADVICE. + +Medications on Admission: +Calcium Acetate 667 mg 2 tabs tid w/ meals +Amlodipine 10mg daily +Metoprolol succinate 100mg daily +Ferrous sulfate 1 tab daily +Calcitriol 0.25mcg daily +Hydralazine 25mg tid +Humalog SS +Lantus 15 units qAM +. +Allergies: Penicillins, Watermelon, Almond Oil + +Discharge Medications: +1. Calcium Acetate 667 mg Capsule [**Known lastname **]: Two (2) Capsule PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +Disp:*180 Capsule(s)* Refills:*2* +2. Amlodipine 5 mg Tablet [**Known lastname **]: Two (2) Tablet PO DAILY (Daily). +Disp:*60 Tablet(s)* Refills:*2* +3. Hydralazine 25 mg Tablet [**Known lastname **]: Two (2) Tablet PO TID (3 times +a day). +Disp:*180 Tablet(s)* Refills:*2* +4. Metoprolol Tartrate 50 mg Tablet [**Known lastname **]: Two (2) Tablet PO BID +(2 times a day). +Disp:*120 Tablet(s)* Refills:*2* +5. Insulin regimen +Please follow printout of insulin dosing (Humalog) +6. Insulin Glargine 100 unit/mL Solution [**Known lastname **]: Fifteen (15) units +Subcutaneous at bedtime. +Disp:*1 month supply* Refills:*2* +7. Calcitriol 0.25 mcg Capsule [**Known lastname **]: One (1) Capsule PO once a +day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Viral Gastroenteritis +Diabetic Ketoacidosis +Diabetes Mellitus type 1 +CKD stage V, requiring initiation of hemodialysis + + +Discharge Condition: +The patient is leaving AGAINST MEDICAL ADVICE given his recent +fevers, pending blood cultures, and recent initiation of +hemodialysis. +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Ambulatory - Independent + + +Discharge Instructions: +*LEAVING AGAINST MEDICAL ADVICE* + +You were admitted to the hospital for nausea and vomiting. +While in the hospital, your sugars were elevated and you were +found to have Diabetic Ketoacidosis (DKA). You were treated +with an insulin drip and your DKA initially resolved. However, +you were not compliant with your diabetic diet and after eating +fried chicken you redeveloped signs of DKA requiring a second +insulin drip. You developed further episodes of DKA during your +hospitalization and each required insulin drip in the intensive +care unit. Additionally, during this hospitalization you were +initiated on hemodialysis which you will require three times a +week. You [**Known lastname 28316**] a fever on [**2-24**] and again on [**2-27**], and blood +cultures were taken to evaluate for any signs of blood +infection. These must be followed by your primary care doctor +or your outpatient nephrologist. Given your recent initiation +of hemodialysis and lengthy hospital course, we advise you to +remain in the hospital while we await the results of these +cultures. As you have decided to leave, it will be AGAINST +MEDICAL ADVICE as we strongly believe that you should continue +to be evaluated for signs and potential sources of infection +given your recent fevers. We want to ensure that you did not +have an active infection and do not have fevers over the next 24 +hours. + +We made the following changes to your home medications: +Hydralazine 50 mg TID (you were taking 25 mg TID prior) +Metoprolol Tartrate 100 [**Hospital1 **] (you were on a long acting +metoprolol once daily prior) + +Please also follow the attached printout of sliding scale +insulin dosing based on your blood sugars. + +Followup Instructions: +Appointment #1 +MD: [**First Name4 (NamePattern1) 2184**] [**Last Name (NamePattern1) 2185**] ([**Company 191**] Post [**Hospital **] Clinic) +Specialty: Internal Medicine +Date/ Time: Monday, [**3-1**], 8:15am +Location: [**Location (un) **], [**Hospital Ward Name 23**] Building, [**Location (un) **] Central +Suite +Phone number: [**Telephone/Fax (1) 250**] +. +Appointment #2 +MD: [**First Name8 (NamePattern2) 7208**] [**Last Name (NamePattern1) 978**] +Specialty: Endocrinology +Date/ Time: Tuesday, [**3-2**], 9 am +Location: [**Hospital **] Clinic +Phone number: [**Telephone/Fax (1) 2490**] + +Apt # 3: +Social Work: +[**3-24**] at 12PM with [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 10927**], LICSW in [**Company 191**] +Please call [**Telephone/Fax (1) 250**] to cancel or change if needed + + + +",50,2145-02-18 20:45:00,2145-02-27 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,DEHYDRATION," +in the er on [**2-18**], his vitals were: t 100.1, p 98, bp 164/90, rr +16, o2 sat 100%. he had abdominal pain, and he was guiac +negative. his initial creatinine was 15.3, his glucose was 162, +and he had a metabolic acidosis with an anion gap of 24 (up from +his baseline of 19, due to his chronic kidney disease). he was +given 2l ivf for hydration, and his anion gap closed to 20. he +was given morphine 4 mg iv x 2 and zofran 4 mg iv x 2, and +admitted to medicine. on transfer to the floor his vitals were: +t 99.2, hr 100, bp 171/90, rr 12, o2sat 97% on room air. +. +on the medicine floor he had worsening nausea, vomiting and +abdominal pain, his glucose rose to 305, his gap increased to 21 +and his ph was 7.27. he received another 2 liters of normal +saline, but become tachypneic. his tachypnea resolved with +diuresis (lasix 20 mg iv). on [**2-19**] the patient was transferred +to the micu for an insulin drip and management of dka. he +received 2 liters of d5w in normal saline, then 1 liter of d5w +with 3 amps of bicarb, then 1 liter of d5w with k+. for his +hematocrit of 20 he received 1 unit of prbcs. his gap was back +down to 21 by 23:00 that evening. + +on [**2-20**] the patient had his first session of hemodialysis. he +declined his renal diet all day, then at midnight had [**state 19827**] +fried chicken brought in from outside. in the early am of [**2-21**] +he developed nausea, vomiting, a glucose of 436 and dka. he had +an ekg that showed no ischemia, and morphine for pain. for +systolic blood pressures from 190-210 he received iv doses of +his home po antihypertensives (hydralazine and metoprolol). the +patient was refusing his calcium capsules because they were too +big to swallow, and tried to order a pizza in instead of +hospital food. + +by [**2-24**] he had been transitioned from insulin drip to insulin +boluses. on [**2-25**] he had his 4th session of dialysis. he wanted +to leave that evening ama (felt he had lost his freedom), but +was convinced to stay. on [**2-26**] he again wanted to leave ama but +was again convinced to stay one more day for a 5th dialysis +session and to arrange optimal outpatient followup. he was +transferred out of the icu to the medicine floor. + +overnight on [**3-31**], he [**date range 28316**] a fever to 100.9. blood +cultures were sent and he underwent his 5th dialysis session. +following his hd session, he was seen by the medical team and +advised to stay in the hospital for one more day to assess for +an infection, given his overnight fever and recent initiation of +hemodialysis. he was advised to stay to ensure he remained +afebrile for 24 hours. mr. [**known lastname 21822**] refused this advise and +decided to sign out against medical advice, despite repeated +discussions with him regarding our decision and desire to +monitor him for another day. + +by problem: +anion gap metabolic acidosis/hyperglycemia/dka. increased above +baseline on presentation probably due to uremia in setting of +dehydration. it slightly improved s/p 2l ivf near baseline gap +of 19. but after brief stay on the regular medicine floor, his +blood sugar elevated into the 200-300s and anion gap increased; +acetone found in serum and ketones seen in urinalysis, +concerning for dka. lactate was normal. in the micu, patient was +started on an insulin gtt and started on intravenous fluids. in +total, patient received 2l d51/2ns, then d5w with 3 amps bicarb +in 1l, then d5w with potassium. he had a picc placed for regular +(every 4 hour) electrolyte checks. patients anion gap decreased +to baseline ~17, given patients underlying end-stage renal +disease/uremia. insulin gtt was discontinued and [**first name8 (namepattern2) **] [**last name (un) **] +recs, patient was started on a fixed lantus and humalog sliding +scale. of note, on [**2-20**], patient refused hospital diet +and had his girlfriend bring him [**state 19827**] fried chicken; his +blood sugars and anion gap increased. patient required +resumption of insulin gtt briefly; he was resumed on insulin +sliding scale and fixed dose, with nutrition consult and social +work following for coping/management of his long-standing, +complicated type 1 diabetes mellitus. + +n/v/d, abdominal pain. given low grade fever and acute onset, +most c/w viral gastroenteritis although possible that this was +exacerbated by uremia. also, patient has a hx of gastroparesis. +abdominal exam nonfocal but with tenderness initially that +resolved. did have an episode of resumed, increased abdominal +pain after consumption of kfc, likely due to brief opening of +anion gap and underlying gastroparesis. lipase was normal. mild +elevation of lfts gradually resolved. pt did not appear fluid +overloaded on exam. patients diarrhea resolved while in micu +and as per above, developed appetite and was able to tolerate po +medications/diet. clostridium difficile toxin was sent and +negative + +acute on chronic renal failure. pt was already in end stage +renal disease (stage 4) on admission. av fisulta had been +recently placed for initiation of hemodialysis. in the setting +of profuse nausea, vomiting and diarrhea, there was also likely +a prerenal component to the bump in creatinine. patient received +2l intravenous fluids in the ed and then approximately 4l to +manage his dka. patient did become hypertensive likely in this +setting. patient was continued on calcitriol, calcium acetate, +and nephrotoxic medications were avoided. renal followed the +patient during this admission and initiated hemodialysis with +good effect on his creatinine and volume status. + +anemia. initially on arrival to the micu, hematocrit was 20, +mildly below baseline of 25 and felt due to the combination of +iron deficiency and ckd. patient did not have emesis or blood in +his stools. patient was transfused one unit of prbc with good +effect. he was continued on iron supplements and may benefit +from epogen with hemodialysis in the future. + +htn. poorly controlled, likely in the setting of initial acute +discomfort and later due to volume overload in the setting of +his esrd and intravenous fluids for dka. patient was ultimately +transitioned to a regimen of metoprolol 100mg twice daily, +amlodipine 10mg daily and hydralazine 50mg three times daily. + +fever. mr. [**known lastname 21822**] [**last name (titles) 28316**] a fever to 100.9 on the night of +[**3-31**]. as discussed above, in the setting of recent +initiation of hemodialysis and pending blood cultures, the +patient was advised to remain in the hospital to be sure he was +afebrile for 24 hours, without signs or symptoms of infection, +and that his blood cultures remained negative. mr. [**known lastname 21822**] +refused, and signed out against medical advice. + + ","PRIMARY: [Diabetes with ketoacidosis, type I [juvenile type], uncontrolled] +SECONDARY: [Acute kidney failure, unspecified; End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Secondary hyperparathyroidism (of renal origin); Intestinal infection due to other organism, not elsewhere classified; Diabetes with renal manifestations, type I [juvenile type], uncontrolled; Diabetes with neurological manifestations, type I [juvenile type], uncontrolled; Gastroparesis; Diabetes with ophthalmic manifestations, type I [juvenile type], uncontrolled; Background diabetic retinopathy; Dehydration; Anemia in chronic kidney disease; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Long-term (current) use of insulin]" +23657,169263.0,13518,2145-03-24,13517,125544.0,2145-02-27,Discharge summary,"Admission Date: [**2145-2-18**] Discharge Date: [**2145-2-27**] + +Date of Birth: [**2112-11-14**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Watermelon / Almond Oil + +Attending:[**First Name3 (LF) 9454**] +Chief Complaint: +Nausea/vomiting, diarrhea --> DKA + +Major Surgical or Invasive Procedure: +PICC line placement +Initiation of hemodialysis + +History of Present Illness: +Mr. [**Known lastname 21822**] is a 32 year-old man with a history of HTN, type 1 +diabetes with gastroparesis, CKD stage V and recently s/p AV +fistula [**2145-1-22**] in anticipation of HD, and anemia who presents +with profuse watery vomiting and watery diarrhea for last 2 +days. No blood or mucus. No fevers but did have night sweats and +chills. He also has crampy abdominal pain improved with bowel +movements. He has only been able to keep down sips. He denies +any lightheadedness. He does still make urine and has not noted +any change in UOP, dysuria, or hematuria. He denies any sick +contacts but did just return to work yesterday after recovering +from placement of a RUE graft on [**1-26**]. He denies any recent +travel or antibiotics use. He states his BS have been in 100s +and he has been taking his lantus 15 in AM, but states this is +what his DKA has felt like in the past. + + +Past Medical History: +- HTN +- DM I since age 19, seen at [**Last Name (un) **]. Complicated by nephropathy, +gastroparesis, proteinuria and possibly retinopathy. +-CKD: thought to be related to HTN and longstanding DMII. +Underwent RUE fistula placement on [**1-26**] for planned HD +initiation. Being considered for liver-pancreas transplant +- Anemia: Thought to be combination of iron deficiency and CKD, +still taking iron +- Depression +- S/p appendectomy [**7-/2144**] + +Social History: +Lives with his girlfriend. [**Name (NI) 1403**] in a clerical setting. Quit +smoking 2 days ago, 5 pk year history. Occasional ETOH. No +illicit drugs. + + +Family History: +Diabetes and heart trouble in grandfather + +Physical Exam: +Physical Exam (on Admission) +Vitals: T 99.2, HR 100, BP 171/90, RR 12, O2sat 97RA. +General: Uncomfortable appearing young man, recently vomited +small amount of nonbloody nonbilous emesis +HEENT: NCAT, MMM, oropharynx clear +Neck: Supple, LAD +Pulm: CTA B +CV: Tachycardic but regular, promienent P2, no m/r/g +Abd: BS hyperactive but not high-pitched, diffuse tenderness +without guarding or rebound, nondistended +Extrem: No LE edema, DP pulses 2+ +Neuro: AAOx 3, grossly nonfocal, no asterixis +Derm: No rash + +Pertinent Results: +On admission to MICU: +pH 7.27 pCO2 24 pO2 233 HCO3 12 BaseXS -13 +140 107 100 AGap=26 +-------------<305 +5.1 12 15.2 +Ca: 8.3 Mg: 2.0 P: 8.0 +ALT: 62 AP: 77 Tbili: 0.1 +AST: 33 [**Doctor First Name **]: 93 Lip: 59 +Osms:346 +Serum Acetmnphn Negative +MCV 88 +wbc 8.2 +plts 272 +hct 20.0 +N:87.2 L:8.7 M:3.1 E:0.8 Bas:0.1 +Lactate: 0.8 + +EKG: NSR at 97 bpm, nl axis and intervals, no ST-T wave changes + + +Chem ([**2-27**]): 140/4.1 101/29 31/8.7 < 70 Ca=8.0 Mg=1.8 +P=4.1 +CBC ([**2-27**]): 6.4 > 22.1 < 233 + +Blood culture [**2-24**] and [**2-27**]: Final read negative + + +Brief Hospital Course: +In the ER on [**2-18**], his vitals were: T 100.1, P 98, BP 164/90, RR +16, O2 sat 100%. He had abdominal pain, and he was guiac +negative. His initial creatinine was 15.3, his glucose was 162, +and he had a metabolic acidosis with an anion gap of 24 (up from +his baseline of 19, due to his chronic kidney disease). He was +given 2L IVF for hydration, and his anion gap closed to 20. He +was given morphine 4 mg IV x 2 and zofran 4 mg IV x 2, and +admitted to medicine. On transfer to the floor his vitals were: +T 99.2, HR 100, BP 171/90, RR 12, O2sat 97% on room air. +. +On the medicine floor he had worsening nausea, vomiting and +abdominal pain, his glucose rose to 305, his gap increased to 21 +and his pH was 7.27. He received another 2 liters of normal +saline, but become tachypneic. His tachypnea resolved with +diuresis (Lasix 20 mg IV). On [**2-19**] the patient was transferred +to the MICU for an insulin drip and management of DKA. He +received 2 liters of D5W in normal saline, then 1 liter of D5W +with 3 amps of bicarb, then 1 liter of D5W with K+. For his +hematocrit of 20 he received 1 unit of pRBCs. His gap was back +down to 21 by 23:00 that evening. + +On [**2-20**] the patient had his first session of hemodialysis. He +declined his renal diet all day, then at midnight had [**State 19827**] +Fried Chicken brought in from outside. In the early AM of [**2-21**] +he developed nausea, vomiting, a glucose of 436 and DKA. He had +an EKG that showed no ischemia, and morphine for pain. For +systolic blood pressures from 190-210 he received IV doses of +his home PO antihypertensives (Hydralazine and Metoprolol). The +patient was refusing his calcium capsules because they were too +big to swallow, and tried to order a pizza in instead of +hospital food. + +By [**2-24**] he had been transitioned from insulin drip to insulin +boluses. On [**2-25**] he had his 4th session of dialysis. He wanted +to leave that evening AMA (felt he had lost his freedom), but +was convinced to stay. On [**2-26**] he again wanted to leave AMA but +was again convinced to stay one more day for a 5th dialysis +session and to arrange optimal outpatient followup. He was +transferred out of the ICU to the medicine floor. + +Overnight on [**3-31**], he [**Date Range 28316**] a fever to 100.9. Blood +cultures were sent and he underwent his 5th dialysis session. +Following his HD session, he was seen by the medical team and +advised to stay in the hospital for one more day to assess for +an infection, given his overnight fever and recent initiation of +hemodialysis. He was advised to stay to ensure he remained +afebrile for 24 hours. Mr. [**Known lastname 21822**] refused this advise and +decided to sign out AGAINST MEDICAL ADVICE, despite repeated +discussions with him regarding our decision and desire to +monitor him for another day. + +By problem: +Anion gap metabolic acidosis/hyperglycemia/DKA. Increased above +baseline on presentation probably due to uremia in setting of +dehydration. It slightly improved s/p 2L IVF near baseline gap +of 19. But after brief stay on the regular medicine floor, his +blood sugar elevated into the 200-300s and anion gap increased; +acetone found in serum and ketones seen in urinalysis, +concerning for DKA. Lactate was normal. In the MICU, patient was +started on an insulin gtt and started on intravenous fluids. In +total, patient received 2L D51/2NS, then D5W with 3 amps bicarb +in 1L, then D5W with potassium. He had a PICC placed for regular +(every 4 hour) electrolyte checks. Patient's anion gap decreased +to baseline ~17, given patient's underlying end-stage renal +disease/uremia. Insulin gtt was discontinued and [**First Name8 (NamePattern2) **] [**Last Name (un) **] +recs, patient was started on a fixed Lantus and Humalog sliding +scale. Of note, on [**2-20**], patient refused hospital diet +and had his girlfriend bring him [**State 19827**] Fried Chicken; his +blood sugars and anion gap increased. Patient required +resumption of insulin gtt briefly; he was resumed on insulin +sliding scale and fixed dose, with Nutrition Consult and Social +Work following for coping/management of his long-standing, +complicated Type 1 Diabetes Mellitus. + +N/V/D, abdominal pain. Given low grade fever and acute onset, +most c/w viral gastroenteritis although possible that this was +exacerbated by uremia. Also, patient has a hx of gastroparesis. +Abdominal exam nonfocal but with tenderness initially that +resolved. Did have an episode of resumed, increased abdominal +pain after consumption of KFC, likely due to brief opening of +anion gap and underlying gastroparesis. Lipase was normal. Mild +elevation of LFTs gradually resolved. Pt did not appear fluid +overloaded on exam. Patient's diarrhea resolved while in MICU +and as per above, developed appetite and was able to tolerate PO +medications/diet. Clostridium difficile toxin was sent and +negative + +Acute on chronic renal failure. Pt was already in end stage +renal disease (stage 4) on admission. AV fisulta had been +recently placed for initiation of hemodialysis. In the setting +of profuse nausea, vomiting and diarrhea, there was also likely +a prerenal component to the bump in creatinine. Patient received +2L intravenous fluids in the ED and then approximately 4L to +manage his DKA. Patient did become hypertensive likely in this +setting. Patient was continued on calcitriol, calcium acetate, +and nephrotoxic medications were avoided. Renal followed the +patient during this admission and initiated hemodialysis with +good effect on his creatinine and volume status. + +Anemia. Initially on arrival to the MICU, hematocrit was 20, +mildly below baseline of 25 and felt due to the combination of +iron deficiency and CKD. Patient did not have emesis or blood in +his stools. Patient was transfused one unit of pRBC with good +effect. He was continued on iron supplements and may benefit +from Epogen with hemodialysis in the future. + +HTN. Poorly controlled, likely in the setting of initial acute +discomfort and later due to volume overload in the setting of +his ESRD and intravenous fluids for DKA. Patient was ultimately +transitioned to a regimen of Metoprolol 100mg twice daily, +Amlodipine 10mg daily and Hydralazine 50mg three times daily. + +Fever. Mr. [**Known lastname 21822**] [**Last Name (Titles) 28316**] a fever to 100.9 on the night of +[**3-31**]. As discussed above, in the setting of recent +initiation of hemodialysis and pending blood cultures, the +patient was advised to remain in the hospital to be sure he was +afebrile for 24 hours, without signs or symptoms of infection, +and that his blood cultures remained negative. Mr. [**Known lastname 21822**] +refused, and signed out AGAINST MEDICAL ADVICE. + +Medications on Admission: +Calcium Acetate 667 mg 2 tabs tid w/ meals +Amlodipine 10mg daily +Metoprolol succinate 100mg daily +Ferrous sulfate 1 tab daily +Calcitriol 0.25mcg daily +Hydralazine 25mg tid +Humalog SS +Lantus 15 units qAM +. +Allergies: Penicillins, Watermelon, Almond Oil + +Discharge Medications: +1. Calcium Acetate 667 mg Capsule [**Known lastname **]: Two (2) Capsule PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +Disp:*180 Capsule(s)* Refills:*2* +2. Amlodipine 5 mg Tablet [**Known lastname **]: Two (2) Tablet PO DAILY (Daily). +Disp:*60 Tablet(s)* Refills:*2* +3. Hydralazine 25 mg Tablet [**Known lastname **]: Two (2) Tablet PO TID (3 times +a day). +Disp:*180 Tablet(s)* Refills:*2* +4. Metoprolol Tartrate 50 mg Tablet [**Known lastname **]: Two (2) Tablet PO BID +(2 times a day). +Disp:*120 Tablet(s)* Refills:*2* +5. Insulin regimen +Please follow printout of insulin dosing (Humalog) +6. Insulin Glargine 100 unit/mL Solution [**Known lastname **]: Fifteen (15) units +Subcutaneous at bedtime. +Disp:*1 month supply* Refills:*2* +7. Calcitriol 0.25 mcg Capsule [**Known lastname **]: One (1) Capsule PO once a +day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Viral Gastroenteritis +Diabetic Ketoacidosis +Diabetes Mellitus type 1 +CKD stage V, requiring initiation of hemodialysis + + +Discharge Condition: +The patient is leaving AGAINST MEDICAL ADVICE given his recent +fevers, pending blood cultures, and recent initiation of +hemodialysis. +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Ambulatory - Independent + + +Discharge Instructions: +*LEAVING AGAINST MEDICAL ADVICE* + +You were admitted to the hospital for nausea and vomiting. +While in the hospital, your sugars were elevated and you were +found to have Diabetic Ketoacidosis (DKA). You were treated +with an insulin drip and your DKA initially resolved. However, +you were not compliant with your diabetic diet and after eating +fried chicken you redeveloped signs of DKA requiring a second +insulin drip. You developed further episodes of DKA during your +hospitalization and each required insulin drip in the intensive +care unit. Additionally, during this hospitalization you were +initiated on hemodialysis which you will require three times a +week. You [**Known lastname 28316**] a fever on [**2-24**] and again on [**2-27**], and blood +cultures were taken to evaluate for any signs of blood +infection. These must be followed by your primary care doctor +or your outpatient nephrologist. Given your recent initiation +of hemodialysis and lengthy hospital course, we advise you to +remain in the hospital while we await the results of these +cultures. As you have decided to leave, it will be AGAINST +MEDICAL ADVICE as we strongly believe that you should continue +to be evaluated for signs and potential sources of infection +given your recent fevers. We want to ensure that you did not +have an active infection and do not have fevers over the next 24 +hours. + +We made the following changes to your home medications: +Hydralazine 50 mg TID (you were taking 25 mg TID prior) +Metoprolol Tartrate 100 [**Hospital1 **] (you were on a long acting +metoprolol once daily prior) + +Please also follow the attached printout of sliding scale +insulin dosing based on your blood sugars. + +Followup Instructions: +Appointment #1 +MD: [**First Name4 (NamePattern1) 2184**] [**Last Name (NamePattern1) 2185**] ([**Company 191**] Post [**Hospital **] Clinic) +Specialty: Internal Medicine +Date/ Time: Monday, [**3-1**], 8:15am +Location: [**Location (un) **], [**Hospital Ward Name 23**] Building, [**Location (un) **] Central +Suite +Phone number: [**Telephone/Fax (1) 250**] +. +Appointment #2 +MD: [**First Name8 (NamePattern2) 7208**] [**Last Name (NamePattern1) 978**] +Specialty: Endocrinology +Date/ Time: Tuesday, [**3-2**], 9 am +Location: [**Hospital **] Clinic +Phone number: [**Telephone/Fax (1) 2490**] + +Apt # 3: +Social Work: +[**3-24**] at 12PM with [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 10927**], LICSW in [**Company 191**] +Please call [**Telephone/Fax (1) 250**] to cancel or change if needed + + + +",25,2145-02-18 20:45:00,2145-02-27 18:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LEFT AGAINST MEDICAL ADVI,DEHYDRATION," +in the er on [**2-18**], his vitals were: t 100.1, p 98, bp 164/90, rr +16, o2 sat 100%. he had abdominal pain, and he was guiac +negative. his initial creatinine was 15.3, his glucose was 162, +and he had a metabolic acidosis with an anion gap of 24 (up from +his baseline of 19, due to his chronic kidney disease). he was +given 2l ivf for hydration, and his anion gap closed to 20. he +was given morphine 4 mg iv x 2 and zofran 4 mg iv x 2, and +admitted to medicine. on transfer to the floor his vitals were: +t 99.2, hr 100, bp 171/90, rr 12, o2sat 97% on room air. +. +on the medicine floor he had worsening nausea, vomiting and +abdominal pain, his glucose rose to 305, his gap increased to 21 +and his ph was 7.27. he received another 2 liters of normal +saline, but become tachypneic. his tachypnea resolved with +diuresis (lasix 20 mg iv). on [**2-19**] the patient was transferred +to the micu for an insulin drip and management of dka. he +received 2 liters of d5w in normal saline, then 1 liter of d5w +with 3 amps of bicarb, then 1 liter of d5w with k+. for his +hematocrit of 20 he received 1 unit of prbcs. his gap was back +down to 21 by 23:00 that evening. + +on [**2-20**] the patient had his first session of hemodialysis. he +declined his renal diet all day, then at midnight had [**state 19827**] +fried chicken brought in from outside. in the early am of [**2-21**] +he developed nausea, vomiting, a glucose of 436 and dka. he had +an ekg that showed no ischemia, and morphine for pain. for +systolic blood pressures from 190-210 he received iv doses of +his home po antihypertensives (hydralazine and metoprolol). the +patient was refusing his calcium capsules because they were too +big to swallow, and tried to order a pizza in instead of +hospital food. + +by [**2-24**] he had been transitioned from insulin drip to insulin +boluses. on [**2-25**] he had his 4th session of dialysis. he wanted +to leave that evening ama (felt he had lost his freedom), but +was convinced to stay. on [**2-26**] he again wanted to leave ama but +was again convinced to stay one more day for a 5th dialysis +session and to arrange optimal outpatient followup. he was +transferred out of the icu to the medicine floor. + +overnight on [**3-31**], he [**date range 28316**] a fever to 100.9. blood +cultures were sent and he underwent his 5th dialysis session. +following his hd session, he was seen by the medical team and +advised to stay in the hospital for one more day to assess for +an infection, given his overnight fever and recent initiation of +hemodialysis. he was advised to stay to ensure he remained +afebrile for 24 hours. mr. [**known lastname 21822**] refused this advise and +decided to sign out against medical advice, despite repeated +discussions with him regarding our decision and desire to +monitor him for another day. + +by problem: +anion gap metabolic acidosis/hyperglycemia/dka. increased above +baseline on presentation probably due to uremia in setting of +dehydration. it slightly improved s/p 2l ivf near baseline gap +of 19. but after brief stay on the regular medicine floor, his +blood sugar elevated into the 200-300s and anion gap increased; +acetone found in serum and ketones seen in urinalysis, +concerning for dka. lactate was normal. in the micu, patient was +started on an insulin gtt and started on intravenous fluids. in +total, patient received 2l d51/2ns, then d5w with 3 amps bicarb +in 1l, then d5w with potassium. he had a picc placed for regular +(every 4 hour) electrolyte checks. patients anion gap decreased +to baseline ~17, given patients underlying end-stage renal +disease/uremia. insulin gtt was discontinued and [**first name8 (namepattern2) **] [**last name (un) **] +recs, patient was started on a fixed lantus and humalog sliding +scale. of note, on [**2-20**], patient refused hospital diet +and had his girlfriend bring him [**state 19827**] fried chicken; his +blood sugars and anion gap increased. patient required +resumption of insulin gtt briefly; he was resumed on insulin +sliding scale and fixed dose, with nutrition consult and social +work following for coping/management of his long-standing, +complicated type 1 diabetes mellitus. + +n/v/d, abdominal pain. given low grade fever and acute onset, +most c/w viral gastroenteritis although possible that this was +exacerbated by uremia. also, patient has a hx of gastroparesis. +abdominal exam nonfocal but with tenderness initially that +resolved. did have an episode of resumed, increased abdominal +pain after consumption of kfc, likely due to brief opening of +anion gap and underlying gastroparesis. lipase was normal. mild +elevation of lfts gradually resolved. pt did not appear fluid +overloaded on exam. patients diarrhea resolved while in micu +and as per above, developed appetite and was able to tolerate po +medications/diet. clostridium difficile toxin was sent and +negative + +acute on chronic renal failure. pt was already in end stage +renal disease (stage 4) on admission. av fisulta had been +recently placed for initiation of hemodialysis. in the setting +of profuse nausea, vomiting and diarrhea, there was also likely +a prerenal component to the bump in creatinine. patient received +2l intravenous fluids in the ed and then approximately 4l to +manage his dka. patient did become hypertensive likely in this +setting. patient was continued on calcitriol, calcium acetate, +and nephrotoxic medications were avoided. renal followed the +patient during this admission and initiated hemodialysis with +good effect on his creatinine and volume status. + +anemia. initially on arrival to the micu, hematocrit was 20, +mildly below baseline of 25 and felt due to the combination of +iron deficiency and ckd. patient did not have emesis or blood in +his stools. patient was transfused one unit of prbc with good +effect. he was continued on iron supplements and may benefit +from epogen with hemodialysis in the future. + +htn. poorly controlled, likely in the setting of initial acute +discomfort and later due to volume overload in the setting of +his esrd and intravenous fluids for dka. patient was ultimately +transitioned to a regimen of metoprolol 100mg twice daily, +amlodipine 10mg daily and hydralazine 50mg three times daily. + +fever. mr. [**known lastname 21822**] [**last name (titles) 28316**] a fever to 100.9 on the night of +[**3-31**]. as discussed above, in the setting of recent +initiation of hemodialysis and pending blood cultures, the +patient was advised to remain in the hospital to be sure he was +afebrile for 24 hours, without signs or symptoms of infection, +and that his blood cultures remained negative. mr. [**known lastname 21822**] +refused, and signed out against medical advice. + + ","PRIMARY: [Diabetes with ketoacidosis, type I [juvenile type], uncontrolled] +SECONDARY: [Acute kidney failure, unspecified; End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Secondary hyperparathyroidism (of renal origin); Intestinal infection due to other organism, not elsewhere classified; Diabetes with renal manifestations, type I [juvenile type], uncontrolled; Diabetes with neurological manifestations, type I [juvenile type], uncontrolled; Gastroparesis; Diabetes with ophthalmic manifestations, type I [juvenile type], uncontrolled; Background diabetic retinopathy; Dehydration; Anemia in chronic kidney disease; Iron deficiency anemia, unspecified; Depressive disorder, not elsewhere classified; Long-term (current) use of insulin]" +25256,144551.0,12435,2162-04-02,12434,170994.0,2162-03-16,Discharge summary,"Admission Date: [**2162-2-4**] Discharge Date: [**2162-3-16**] + +Date of Birth: [**2123-3-28**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 2485**] +Chief Complaint: +Chief Complaint: Low oxygen saturation at clinic +Reason for MICU admission: hypercarbic respiratory failure + + +Major Surgical or Invasive Procedure: +Intubation/mechanical ventilation +Arterial line placement +s/p tracheostomy placement [**2162-3-8**] + +History of Present Illness: +38M with NHL s/p alloSCT [**2155**] and DLI [**2156**], in remission but +with chronic GVHD including bronchiolitis obliterans and severe +restrictive lung disease, initially admitted to [**Year (4 digits) 3242**] service on +[**2-4**] with shortness of breath, now transferred to MICU for +hypercarbic respiratory failure. +. +He was at routine clinic visit on [**2-4**] and noted shortness of +breath and sats 93% RA. He had had recent outpatient treatment +for pneumonia starting [**1-21**], briefly interrupted due to elevated +bilirubin. Has been on very low dose IL-2 subcutaneously at +home, last received prior to admission. +. +During his hospital course, he was treated with cefepime and +levofloxacin (now day 14). Pulmonary was consulted and +recommended chest PT and hypertonic saline. He remained on RA +for the most part, maintaining sats in 90-97% range. Afebrile +with exception of T100.5 on [**2-9**] and 100.3 this morning. IL-2 +was stopped at admission and tacrolimus was trialed for enhanced +immunosuppresion, but was stopped today due to development of +tremor in the past few days. +On rounds this AM he noted fatigue without new respiratory +symptoms. Got chest PT, lasix 20 mg, vancomycin, and nebs. +During the course of the morning he looked more fatigued then +started working harder to breathe. CXR was grossly unchanged. He +was started on 1-2L O2. Somnolence then developed and he needed +to be lifted from chair to bed. ABG done and pending at the time +of transfer. He was working hard to breathe but not responding +to verbal stimuli. He was rapidly transported to the [**Hospital Unit Name 153**] and +intubated. Immediately prior to intubation he was apneic and +required bag ventilation. +. +Review of Systems: +(+) Unable to obtain; see admission note. Notables include +significant weight loss for which GI was consulted, and +development of bilateral LE edema (as well as some in UEs). + + +Past Medical History: +Past Oncologic History: +- [**4-/2154**] p/w fevers, night sweats, and weight loss in the +setting of a left inguinal lymph node. +- CT scan: 15x14x10cm mass in the LUQ. +- Bx grade II/III follicular lymphoma. +- Treated with six cycles of CHOP/Rituxan with good response, +but showed evidence for relapse in [**12/2154**] and was treated with +MINE chemotherapy for two cycles. +- [**3-/2155**]: Underwent stem cell mobilization with Cytoxan followed +by autologous stem cell transplant in +- [**7-/2155**]: Noted for disease recurrence. He was initially treated +with a course of Rituxan without response followed by Zevalin +with +- [**3-/2156**]: Noted progression of his disease. He was treated with + +one cycle of [**Hospital1 **] followed by one cycle of ESHAP. +- [**2156-7-29**]: Nonmyeloablative allogeneic stem cell transplant +with a [**5-30**] HLA-matched unrelated donor with Campath conditioning + +- Six-month follow-up CT noted for disease progression. +- [**1-/2157**]: Received donor lymphocyte infusion in , complicated by +acute liver/GI GVHD grade IV, for which [**Known firstname **] required a +prolonged hospitalization in the summer of [**2156**]. +- Multiple GI bleeds requiring ICU admissions and multiple +transfusions and embolization of his bleeding. +- Noted to have CNS lesions felt consistent with PTLD and this +was treated with a course of Rituxan. No evidence for recurrence +of the PTLD. +- Acute liver GVHD, on CellCept, prednisone, and photophoresis. + +- [**2157-12-28**] Photophoresis was d/c'd due to episodes of +bacteremia and eventual removal of his apheresis catheter. +- [**2158-6-13**] restarted photopheresis on a weekly basis on , but +then discontinued this again on [**2158-9-7**] as this was felt not +to be making any impact on his liver function tests. +- undergone phlebotomy due to iron overload with corresponding +drop in his ferritin. He has continued with transient rises in +his transaminases and bilirubin and has remained on varying +doses of CellCept and prednisone which has been slowly tapered +over the time. +- [**2160-1-10**] CellCept discontinued. +- [**2159-1-19**] admission due to increasing right hip pain. MRI +revealed edema and infiltrating process in the psoas muscle +bilaterally. After extensive workup, this was felt related to an +infection and required several admissions with completion of +antibiotics in 03/[**2158**]. +- [**7-/2160**]: Last scans showed no evidence for lymphom and he has +remained in remission. +- [**2160-10-20**]: URI and treatment with course of Levaquin. +- [**2160-11-13**] completed a 4 week course of Rituxan to treat his +GVHD. +-In [**5-/2161**], noted to have tiny echogenic nodule on abdominal +[**Year (4 digits) 950**]. MRI of the liver also showed this nodule but was not +as concerning on review and he is due to have a repeat MRI +imaging in early [**Month (only) **]. +-- GI varices and attempts at banding have been unsuccessful due +to difficulty with passing the necessary instruments. He has +been on a low dose beta blocker as well as simvastatin, which +was started on [**2161-7-7**] to help with medical management of his +varices. +-On [**2161-8-3**], worsening cough and was noted to have a small +new pneumothorax in the left apical area. This has essentially +resolved over time +- Issues with weight loss (followed by Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **]); +multiple tests done with no etiology found; question +malabsorption related to GVHD +- Has on and off respiratory infections and has been treated +with antibiotics with possible pneumonia. Question underlying +exacerbations of pulmonary GVHD in setting of his URIs. +- Currently receives IVIG every month. +. +Other Past Medical History: +1. Non-Hodgkin's lymphoma s/p allo SCT +2. Grade 4 Acute GVHD of GI/liver following DLI with GI bleed, +chronic transaminitis, portal HTN with esophageal varices (not +able to band) +3. History of intracranial lesions felt consistent with PTLD. +4. Extensinve chronic GVHD of lung, liver, skin, mucous +membranes. +5. Grade II esophageal varices, intollerant to beta blockade. +6. HSV in nasal washing [**11/2159**](completed course of Valtrex) +7. Hypothyroidism +8. hx of Psoas muscle infection +. + + +Social History: +Smoke: never +EtOH: none currently; occassional use prior to NHL dx +Drugs: never +Born in [**Country **] and moved to the U.S. for college ([**Hospital1 **]). +Married in [**2160-8-25**] and lives in [**Location **]. No children. +Stays at home and writes (currently writing a book on being +diagnosed with cancer at young age). + + +Family History: +Without history of lymphoma or other cancers in the family +No FHx of DM or HTN +Mother: Alive, Thyroid disease +Father: [**Name (NI) 38646**] cardiac cath with angioplasty of 2 vessels, +asthma +2 older brothers: alive and well + +Physical Exam: +VS: 96.6 129 110/77 21 100% +AC FiO2 100%, VT: 350, RR: 24, PEEP 5 +GEN: intubated, sedated, cachectic. +HEENT: PERRL 4->3, oropharynx clear. +Neck: Thin, JVD to 3 cm ASA. +CV: tachy, regular, S1 S2, no mrg apprciated. +PULM: Poor air entry bilaterally, no wheezes/rhonchi/crackles +appreciated. +ABD: audible bowel sounds, tense abdomen though appears +nontender. +LIMBS: 2+ pitting edema bilaterally, warm. +NEURO: sedated, moving all extremities prior to intubation. Post +intubation with some posturing and tremors of RUE in particular, +?tacro effect. +SKIN: diffuse scattered GVHD associated rash. + + +Pertinent Results: +CBC +[**2162-2-20**] 03:55AM BLOOD WBC-6.7 RBC-2.94* Hgb-9.0* Hct-27.5* +MCV-93 MCH-30.6 MCHC-32.7 RDW-16.3* Plt Ct-95* +[**2162-2-19**] 04:14AM BLOOD WBC-8.9 RBC-3.21* Hgb-9.5* Hct-30.4* +MCV-95 MCH-29.7 MCHC-31.3 RDW-16.4* Plt Ct-100* +[**2162-2-18**] 04:29AM BLOOD WBC-9.8 RBC-3.32* Hgb-9.9* Hct-31.8* +MCV-96 MCH-29.7 MCHC-31.0 RDW-16.4* Plt Ct-130* +[**2162-2-17**] 01:08PM BLOOD WBC-11.0 RBC-3.63* Hgb-10.7* Hct-35.6* +MCV-98 MCH-29.5 MCHC-30.1* RDW-15.8* Plt Ct-135* + +CHEMISTRY +[**2162-2-20**] 03:55AM BLOOD Glucose-131* UreaN-19 Creat-0.3* Na-138 +K-4.2 Cl-100 HCO3-32 AnGap-10 +[**2162-2-19**] 04:14AM BLOOD Glucose-88 UreaN-20 Creat-0.3* Na-137 +K-4.2 Cl-102 HCO3-30 AnGap-9 +[**2162-2-18**] 04:29AM BLOOD Glucose-83 UreaN-21* Creat-0.4* Na-138 +K-4.3 Cl-101 HCO3-30 AnGap-11 +[**2162-2-17**] 01:08PM BLOOD Glucose-168* UreaN-27* Creat-0.4* Na-141 +K-4.4 Cl-97 HCO3-37* AnGap-11 +[**2162-2-19**] 04:14AM BLOOD ALT-51* AST-67* AlkPhos-249* TotBili-1.5 +[**2162-2-17**] 01:08PM BLOOD ALT-76* AST-72* LD(LDH)-332* CK(CPK)-31* +AlkPhos-297* TotBili-1.2 +[**2162-2-17**] 12:29AM BLOOD ALT-80* AST-78* LD(LDH)-278* AlkPhos-287* +TotBili-1.0 +[**2162-2-16**] 12:00AM BLOOD ALT-86* AST-109* LD(LDH)-317* +AlkPhos-338* TotBili-1.2 DirBili-0.8* IndBili-0.4 +[**2162-2-20**] 03:55AM BLOOD Calcium-8.5 Phos-3.0 Mg-1.7 + +MICRO +[**2162-3-4**] 1:08 pm BRONCHOALVEOLAR LAVAGE RIGHT LOWER LOBE. + +GRAM STAIN (Final [**2162-3-4**]): 3+ (5-10 per 1000X FIELD): +POLYMORPHONUCLEAR LEUKOCYTES. NO MICROORGANISMS SEEN. + +RESPIRATORY CULTURE (Final [**2162-3-8**]): KLEBSIELLA PNEUMONIAE. +~1000/ML. + +SENSITIVITIES: MIC expressed in MCG/ML + +_________________________________________________________ + KLEBSIELLA PNEUMONIAE + | +AMPICILLIN/SULBACTAM-- =>32 R +CEFAZOLIN------------- <=4 S +CEFEPIME-------------- <=1 S +CEFTAZIDIME----------- <=1 S +CEFTRIAXONE----------- <=1 S +CIPROFLOXACIN--------- =>4 R +GENTAMICIN------------ <=1 S +MEROPENEM-------------<=0.25 S +PIPERACILLIN/TAZO----- =>128 R +TOBRAMYCIN------------ <=1 S +TRIMETHOPRIM/SULFA---- =>16 R + +REPORTS +CXR PA/LAT [**2162-2-4**]: +Increased consolidation at the base of the left lung is +accompanied by new +small left pleural effusion, could be pneumonia. Right lung +generally clear aside from mild peribronchial infiltration in +the right upper lobe. Heart size normal. No evidence of central +adenopathy. + +ECHO [**2162-2-18**] +IMPRESSION: Vigorous biventircular systolic function. No +clinically-significant valvular disease seen. Normal estimated +intracardiac filling pressures. + +ABDOMINAL U/S [**2162-2-19**]: +FINDINGS: Since prior examination, there has been interval +development of a moderate-to-severe amount of intra-abdominal +ascites. The largest pocket of ascites is noted within the right +lower quadrant measuring up to 13.6 cm in anterior-posterior +dimensions, approximately 1 cm from the skin surface. +IMPRESSION: Moderate-to-severe intra-abdominal ascites with +largest pocket in right lower quadrant +. +CXR [**2162-3-8**]: +Left lower lobe remains entirely consolidated. Small left +pleural effusion is larger. Right infrahilar consolidation is +stable. Tip of the new tracheostomy tube is just a few +millimeters above the carina, probably not +optimal. Feeding tube ends in the stomach. No right pleural +effusion. Heart size normal. Right PIC line ends in the upper +right atrium. Findings were discussed by telephone with the +patient's nurse at the time of dictation. +. +Discharge Labs: + +[**2162-3-10**] 05:19AM BLOOD WBC-5.5 RBC-2.84* Hgb-8.2* Hct-27.2* +MCV-96 MCH-28.9 MCHC-30.1* RDW-16.3* Plt Ct-166 +[**2162-3-6**] 03:15AM BLOOD Neuts-77* Bands-2 Lymphs-15* Monos-4 +Eos-1 Baso-0 Atyps-0 Metas-1* Myelos-0 +[**2162-3-10**] 05:19AM BLOOD Glucose-66* UreaN-13 Creat-0.2* Na-142 +K-3.6 Cl-108 HCO3-24 AnGap-14 +[**2162-3-8**] 03:47AM BLOOD ALT-40 AST-41* LD(LDH)-225 AlkPhos-259* +TotBili-0.9 +[**2162-3-10**] 05:19AM BLOOD Calcium-6.6* Phos-1.5* Mg-1.5* +[**2162-2-25**] 03:20AM BLOOD calTIBC-316 VitB12-1776* Folate-GREATER +TH Ferritn-230 TRF-243 +[**2162-3-3**] 12:06AM BLOOD TSH-0.71 +[**2162-2-17**] 08:50AM BLOOD tacroFK-9.1 +[**2162-3-8**] 08:51PM BLOOD Type-ART pO2-177* pCO2-65* pH-7.33* +calTCO2-36* Base XS-6 +[**2162-3-4**] 04:27AM BLOOD Lactate-1.0 + +Brief Hospital Course: +38M with NHL s/p alloBMT complicated by multi-organ GVHD and BO +with severe baseline lung disease and CO2 retention, presenting +with dyspnea and cough, now transfered to [**Hospital Unit Name 153**] for hypercarbic +respiratory failure. +. +# Hypercarbic respiratory failure. The etiology of his +respiratory failure was thought to be most likely [**1-26**] 3 factors: +1) worsening pulmonary GVHD 2) cirrhosis also likely [**1-26**] GVHD +and may benefit from a therapeutic para to help his breathing 3) +low negative inspiratory force (NIF) values, suggestive of weak +muscles of respiration, possibly secondary to ICU or steroid +myopathy. Infection thought to be less likely given negative +BAL. CTA negative for PE. Therefore, although vanc, levo, and +cefepime were continued, pt was started on methylprednisolone +50mg IV Q12H. CT head for somnolence negative. After discussion +with his oncologist and the primary medical team, CT surgery was +consulted for tracheostomy and GI was consulted about placing a +PEG tube. Patient was tried several times on PSV and a vent +weaning trial in the days leading up to the scheduled operation +and the patient was noted to tolerate progressively lower +pressure support. PEG and trach placement was tentatively +scheduled for [**2162-2-26**] but the patient's condition improved and he +was extubated on the morning of [**2162-2-26**]. He intermittently +required NIPPV for respiratory fatigue but in general his ABGs +were reassuring enough for him to remain on oxygen +supplementation alone. On [**2-28**], the patient appeared to be in +respiratory fatigue which continued and worsened with increasing +tachycardia in the setting of pt spiking fevers. As a result, he +was reintubated on [**2162-3-3**]. A bronchoscopy was performed which +revealed GNRs in the sputum. He was kept on broad spectrum +antibiotic coverage and was switched to Meropenem when BAL +cultures showed Klebsiella pneumoniae sensitive to this +antibiotic. On [**3-8**], a trach was placed at the bedside without +difficulty. He was able to tolerate breathing without +ventilatory support for 1.5 hours by [**2162-3-14**], but otherwise was +on pressure support, with a PSV of 12 and PEEP of 5. He +completed an 8 day course of meropenem on [**2162-3-15**]. +. +#Fever. The patient was noted to have increasing leukocytosis +and low grade temps on [**2162-3-2**]. [**Date Range 3242**] was consulted and recommended +that we check CT sinus, CT chest, and start empiric antibiotic +treatment with vanc/cefepime/voriconazole. The results of the +CT sinus and CT chest were consistent with marked interval +worsening of right lower lobe pneumonia.. Culture data from BAL +was consistent with meropenem-sensitive klebsiella pneumonia. +The patient was started on this antibiotic with resolution of +his fevers. Just prior to discharge, the patient thought he may +have aspirated some contents of his NG tube which had been +dislodged overnight. A new Dobhoff was placed by IR on [**3-10**]. He +did have a low grade fever to 100.5F on [**3-10**]. As a result, he +was started on Vancomycin, per [**Month/Year (2) 3242**] recommendations. C. difficile +toxin was negative x 2, and vancomycin was stopped on [**2162-3-12**], +with no further fevers. +. +#Diarrhea/loose stools. Mr. [**Known lastname 38598**] reported frequent loose stools +on [**3-11**]. He was started empirically on po vanco, per [**Month/Year (2) 3242**] +recomendations, and stopped once C. Diff toxin was negative. +. +# Hypotension. Normotensive prior to intubation but had some +prolonged low BPs most likely secondary to positive pressure +effects and sedation. CTA negative for PE. TTE also wnl. +Neosynephrine quickly weaned off. Normotensive since +extubation. +. +# Tremor. Occurring on [**Month/Year (2) 3242**] floor prior to events, though ?med +effect from tacro. Low suspicion for seizure activity given +chronicity and with normal mental status prior. Resolved during +ICU stay. +. +# Edema. New this admission, though to be [**1-26**] IVFs. Past +echocardiograms have all been within normal limits. A TTE on +this admission was similarly normal, but his symptoms did +self-resolve. [**Month (only) 116**] have been related to cirrhosis although +albumin only 3.6. +. +# Non-Hodgkin's lymphoma s/p allo [**Month (only) 3242**]: Most recent PET scan with +no evidence of recurrent disease and he remains in remission. +. +# GVHD. Respiratory plan as above, prednisone and MMF per above, +PPx with bactrim DS and Acyclovir. On [**2162-3-13**], patient was +treated with one dose of rituxan. +. +# Elevated LFTs. At baseline from GVHD. +. +# Hypothyroidism. No active issues. Levothyroxine 125 mcg daily +M-Saturday was continued. +. +# Gastric varices. Asymptomatic. No e/o GI bleed. Metoprolol +restarted at 12.5 mg PO BID. +. +# Nutrition: Patient was advanced to a regular diet with +supplemental Ensure on [**2162-2-26**] after extubation. A Dobhoff was +placed by IR on [**3-10**] as patient was unable to keep up with +adequate po intake for caloric needs. He will require tube feeds +based on nutrition recommendations until he is able to maintain +adequate po intake. +. +CODE STATUS: FULL CODE (confirmed) + +Medications on Admission: +ALBUTEROL SULFATE - 90 mcg HFA Aerosol Inhaler - 2 puffs(s) +inhaled q 4-6h as needed for chest tightness/SOB/exposure to +cold +air +ALBUTEROL SULFATE - 2.5 mg/3 mL (0.083 %) Solution for +Nebulization - 1 neb inhaled four times daily as needed for +shortness of breath +AZITHROMYCIN - (On Hold from [**2162-1-28**] to unknown for on +levaquin) - 250 mg Tablet - 1 (One) Tablet(s) by mouth three +times a week Start after Zpak completed +BUDESONIDE-FORMOTEROL [SYMBICORT] - 160 mcg-4.5 mcg/Actuation +HFA +Aerosol Inhaler - 2 puffs inhaled twice daily +ERGOCALCIFEROL (VITAMIN D2) [VITAMIN D] - 50,000 unit Capsule - +1 +(One) Capsule(s) by mouth once a week +ERYTHROMYCIN - (Prescribed by Other Provider) - 5 mg/gram +Ointment - [**12-28**] inch to both eyes at bedtime. +FAMCICLOVIR - 250 mg Tablet - 2 (Two) Tablet(s) by mouth twice a + +day +IPRATROPIUM BROMIDE - 0.2 mg/mL (0.02 %) Solution - 1 vial +nebulized three times daily as needed for cough and shortness of + +breath +ISOSORBIDE DINITRATE - 5 mg Tablet - one to 1(one) Tablet(s) by + +mouth daily +LEVOFLOXACIN [LEVAQUIN] - (Prescribed by Other Provider) - 250 +mg Tablet - 2 Tablet(s) by mouth once a day for 14 days started + +on [**2162-1-21**] +LEVOTHYROXINE [LEVOXYL] - 125 mcg Tablet - 1 (One) Tablet(s) by + +mouth once a day Monday - Saturday. - No Substitution +LIPASE-PROTEASE-AMYLASE [CREON] - (Prescribed by Other Provider) + +- 60,000 unit-[**Unit Number **],000 unit-[**Unit Number **],000 unit Capsule, Delayed +Release(E.C.) - 3 Capsule(s) by mouth three times a day Take +with +meals +LOFEMAX - (Prescribed by Other Provider) - - 1 drop to right +eye daily +LORAZEPAM - 0.5 mg Tablet - 1 to 2 Tablet(s) by mouth at bedtime + +as needed for insomnia +METOPROLOL SUCCINATE - 25 mg Tablet Sustained Release 24 hr - 1 + +(One) Tablet(s) by mouth once a day +MYCOPHENOLATE MOFETIL - (Prescribed by Other Provider: [**Name Initial (NameIs) **]) - + +250 mg Capsule - 1 (One) Capsule(s) by mouth twice a day +NYSTATIN - 100,000 unit/mL Suspension - 5 (Five) ml(s) by mouth + +four times a day +PREDNISONE - (Prescribed by Other Provider) - 10 mg Tablet - 2 +(Two) Tablet(s) by mouth once a day +SIMVASTATIN - 20 mg Tablet - 1 Tablet(s) by mouth daily +SULFAMETHOXAZOLE-TRIMETHOPRIM - 800 mg-160 mg Tablet - 1 (One) +Tablet(s) by mouth three times a week (Monday, Wednesday, +Friday) +MULTIVITAMINS-MINERALS-LUTEIN [CENTRUM SILVER] - (Prescribed by + +Other Provider) - 500 mcg-250 mcg Tablet, Chewable - 1 (One) +Tablet(s) by mouth once a day + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +Non hodgkins lymphoma +Hypoxic respiratory failure +Klebsiella Pneumonia +Bronchiolitis Obliterans +GVHD + + +Discharge Condition: +stable, s/p tracheostomy, afebrile, on PSV. + +Followup Instructions: +Patient should have close monitoring and follow-up with [**Hospital1 3242**] +while at rehab, and should see his oncologist within 1 week of +discharge from rehabilitation facility. + + +",17,2162-02-04 17:24:00,2162-03-16 11:30:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,LONG TERM CARE HOSPITAL,LYMPHOMA," +38m with nhl s/p allobmt complicated by multi-organ gvhd and bo +with severe baseline lung disease and co2 retention, presenting +with dyspnea and cough, now transfered to [**hospital unit name 153**] for hypercarbic +respiratory failure. +. +# hypercarbic respiratory failure. the etiology of his +respiratory failure was thought to be most likely [**1-26**] 3 factors: +1) worsening pulmonary gvhd 2) cirrhosis also likely [**1-26**] gvhd +and may benefit from a therapeutic para to help his breathing 3) +low negative inspiratory force (nif) values, suggestive of weak +muscles of respiration, possibly secondary to icu or steroid +myopathy. infection thought to be less likely given negative +bal. cta negative for pe. therefore, although vanc, levo, and +cefepime were continued, pt was started on methylprednisolone +50mg iv q12h. ct head for somnolence negative. after discussion +with his oncologist and the primary medical team, ct surgery was +consulted for tracheostomy and gi was consulted about placing a +peg tube. patient was tried several times on psv and a vent +weaning trial in the days leading up to the scheduled operation +and the patient was noted to tolerate progressively lower +pressure support. peg and trach placement was tentatively +scheduled for [**2162-2-26**] but the patients condition improved and he +was extubated on the morning of [**2162-2-26**]. he intermittently +required nippv for respiratory fatigue but in general his abgs +were reassuring enough for him to remain on oxygen +supplementation alone. on [**2-28**], the patient appeared to be in +respiratory fatigue which continued and worsened with increasing +tachycardia in the setting of pt spiking fevers. as a result, he +was reintubated on [**2162-3-3**]. a bronchoscopy was performed which +revealed gnrs in the sputum. he was kept on broad spectrum +antibiotic coverage and was switched to meropenem when bal +cultures showed klebsiella pneumoniae sensitive to this +antibiotic. on [**3-8**], a trach was placed at the bedside without +difficulty. he was able to tolerate breathing without +ventilatory support for 1.5 hours by [**2162-3-14**], but otherwise was +on pressure support, with a psv of 12 and peep of 5. he +completed an 8 day course of meropenem on [**2162-3-15**]. +. +#fever. the patient was noted to have increasing leukocytosis +and low grade temps on [**2162-3-2**]. [**date range 3242**] was consulted and recommended +that we check ct sinus, ct chest, and start empiric antibiotic +treatment with vanc/cefepime/voriconazole. the results of the +ct sinus and ct chest were consistent with marked interval +worsening of right lower lobe pneumonia.. culture data from bal +was consistent with meropenem-sensitive klebsiella pneumonia. +the patient was started on this antibiotic with resolution of +his fevers. just prior to discharge, the patient thought he may +have aspirated some contents of his ng tube which had been +dislodged overnight. a new dobhoff was placed by ir on [**3-10**]. he +did have a low grade fever to 100.5f on [**3-10**]. as a result, he +was started on vancomycin, per [**month/year (2) 3242**] recommendations. c. difficile +toxin was negative x 2, and vancomycin was stopped on [**2162-3-12**], +with no further fevers. +. +#diarrhea/loose stools. mr. [**known lastname 38598**] reported frequent loose stools +on [**3-11**]. he was started empirically on po vanco, per [**month/year (2) 3242**] +recomendations, and stopped once c. diff toxin was negative. +. +# hypotension. normotensive prior to intubation but had some +prolonged low bps most likely secondary to positive pressure +effects and sedation. cta negative for pe. tte also wnl. +neosynephrine quickly weaned off. normotensive since +extubation. +. +# tremor. occurring on [**month/year (2) 3242**] floor prior to events, though ?med +effect from tacro. low suspicion for seizure activity given +chronicity and with normal mental status prior. resolved during +icu stay. +. +# edema. new this admission, though to be [**1-26**] ivfs. past +echocardiograms have all been within normal limits. a tte on +this admission was similarly normal, but his symptoms did +self-resolve. [**month (only) 116**] have been related to cirrhosis although +albumin only 3.6. +. +# non-hodgkins lymphoma s/p allo [**month (only) 3242**]: most recent pet scan with +no evidence of recurrent disease and he remains in remission. +. +# gvhd. respiratory plan as above, prednisone and mmf per above, +ppx with bactrim ds and acyclovir. on [**2162-3-13**], patient was +treated with one dose of rituxan. +. +# elevated lfts. at baseline from gvhd. +. +# hypothyroidism. no active issues. levothyroxine 125 mcg daily +m-saturday was continued. +. +# gastric varices. asymptomatic. no e/o gi bleed. metoprolol +restarted at 12.5 mg po bid. +. +# nutrition: patient was advanced to a regular diet with +supplemental ensure on [**2162-2-26**] after extubation. a dobhoff was +placed by ir on [**3-10**] as patient was unable to keep up with +adequate po intake for caloric needs. he will require tube feeds +based on nutrition recommendations until he is able to maintain +adequate po intake. +. +code status: full code (confirmed) + + ","PRIMARY: [Acute and chronic respiratory failure] +SECONDARY: [Pneumonia, organism unspecified; Pneumonia due to Klebsiella pneumoniae; Pneumonitis due to inhalation of food or vomitus; Dependence on respirator, status; Complications of transplanted bone marrow; Chronic graft-versus-host disease; Nodular lymphoma, unspecified site, extranodal and solid organ sites; Portal hypertension; Esophageal varices in diseases classified elsewhere, without mention of bleeding; Other specified alveolar and parietoalveolar pneumonopathies; Unspecified intestinal malabsorption; Paroxysmal supraventricular tachycardia; Unspecified pleural effusion; Surgical operation with transplant of whole organ causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Accidents occurring in other specified places; Varices of other sites; Unspecified acquired hypothyroidism; Secondary diabetes mellitus without mention of complication, not stated as uncontrolled, or unspecified; Adrenal cortical steroids causing adverse effects in therapeutic use; Hypoxemia; Nonspecific low blood pressure reading; Iron deficiency anemia, unspecified; Cirrhosis of liver without mention of alcohol]" +25696,188176.0,11473,2170-11-12,11472,192616.0,2170-05-21,Discharge summary,"Admission Date: [**2170-5-5**] Discharge Date: [**2170-5-21**] + +Date of Birth: [**2118-2-1**] Sex: M + +Service: MEDICINE + +Allergies: +Ciprofloxacin + +Attending:[**First Name3 (LF) 6565**] +Chief Complaint: +right lower extremity swelling + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +52 year old man with a PMH of metatstatic prostate cancer, PE, +DVT on lovenox, hx of IVC filter in [**2168-4-9**] presents with +increased leg swelling. Patient reports right leg pain that +acutely started on the day prior to admission. He likens the +sensation to feeling as though something were crawling up his +leg and pain was reproduced with standing. These symptoms are +similar to symptoms he's experienced with previous DVTs. He +denies any injury to his leg and also denies prolonged travel or +immobility. He also noticed shortness of breath without chest +pain. Given these symptoms, he presented to the [**Hospital1 18**] ED for +further evaluation. +. +In the [**Hospital1 18**] ED, vitals were as follows T - 98.8, HR - 117, BP - +128/80, RR - 12, O2 - 99%RA. CXR was unremarkable. LENIs showed +non-occlusive DVT on the right. CTA chest was ordered, but was +pending at the time of admission. Given concern for DVT/PE, IV +Heparin was started, though because of the GIB, patient was +admitted to the ICU for concern of GIB in the setting of +anticoagulation + + +Past Medical History: +PAST MEDICAL HISTORY: +1. Metastatic prostate cancer to bone refractory to hormone +therapy +2. Bilateral LE DVTs complicated by bilateral PE [**4-/2168**], +treated with enoxoparin then warfarin, and status post IVC +filter placement 04/[**2168**]. Last with DVT on [**2169-1-7**], now on +enoxoparin 120 mg daily. +3. Psoriasis +4. Hypercholesterolemia +5. Seasonal allergies +6. Obstructive sleep apnea on CPAP +. +PAST ONCOLOGIC HISTORY (per prior discharge summary): +Metastatic prostate cancer to bone refractory to hormone therapy +s/p cycle 1 of Carboplatin and Taxotere [**2168-12-15**]. Dx in [**2163**] as +[**Doctor Last Name **] 8 s/p surgical prostatectomy with XRT to T9 spinal +metastasis in [**11-12**] followed by hormonal therapy, Taxotere (2 +cycles), ketoconazole, hydrocortisone, mitoxantrone, and DES. He +was recently noted to have a rise in his PSA to the 400 range, +and a L-spine MRI on [**11-15**] showed multiple spine metastatic foci +(no prior MRI L-spine for comparison, bone scan in [**6-/2168**] +without clear spine metastases). He received his +first cycle of Carboplatin and Taxotere on [**2168-12-15**]. + + +Social History: +He lives at home with his wife and his 12 year-old son. [**Name (NI) **] does + +not smoke. He denies tobacco, alcohol or illicit drug use. He +formerly worked as heavy machine operator at [**Location (un) 86**] Water and +Sewage. + + +Family History: +No family history of thrombophilic disorders. + +Physical Exam: +PHYSICAL EXAM: +Vitals: T - 99.5, BP - 131/79, HR - 119, RR - 16, O2 - 99% 3 L +NC +Gen: Awake, alert, NAD +HEENT: NC/AT; PERRLA, EOMI; OP clear, nonerythematous +CV: Distant heart sounds, [**2-10**] body habitus, but otherwise, no +m/r/g +Pulm: Small inspiratory crackles at the bases bilaterally +Abd: Soft, NT, ND + BS +Rectal: Guaiac negative +Ext: No c/c/e; RLE markedly bigger than LLE with mild erythema +and keratoses on shins + + +Pertinent Results: +CTA (prelim read): +IMPRESSION: +1. No evidence of pulmonary embolism. +2. Innumerable diffuse osseous metastatic sclerotic lesions. +3. Stable T9 compression fracture. +4. Fatty liver. + +LENIS: +IMPRESSION: Partially occlusive thrombus within the mid right +superficial femoral vein consistent with chronic recanalized +DVT. + +CXR: +FINDINGS: Single bedside AP examination labeled ""upright"" with +excessive lordotic positioning, as compared with studies dated +[**2170-4-11**] and [**2169-2-21**]; the overall appearance has not much changed. +The lung volumes remain low with bibasilar vascular crowding, +but no focal airspace process. Allowing for these factors, the +heart is top normal in size with only equivocal upper zone +pulmonary vascular redistribution, but no overt CHF or pleural +effusion. + +Brief Hospital Course: +52-year-old man with metastatic prostate cancer, not on active +chemo with recurrent DVTs/PEs despite anticoagulation, also with +recent GIB, presented with LE swelling, found to have RLE DVT. +. +# DVT: The patient presented with worse clot burden. He was on +enoxaparin at home. Anti-Xa activity not checked on admission. +He underwent an IVC venogram and mechanical thrombolysis with +local TPA on [**2170-5-7**]. Heparin was then discontinued, and he was +started on enoxaparin 120 mg [**Hospital1 **] on [**2170-5-8**]. (The patient had +been on enoxaparin 80 mg [**Hospital1 **] before this admission.) His anti-Xa +activity was therapeutic. He was sent home with enoxaparin 120 +mg SC bid. +. +# Chronic pain: the patient experienced significant pain from +bone metastases during this admission, requiring hydromorphone +PCA. Palliative care was consulted on pain management. His pain +gradually improved and he was discharged with methadone 20 mg PO +qid and hydromorphone 12-24 mg PO q2h prn as well as gabapentin. + +. +# Intermittent delirium: most likely from high-dose pain meds. +His delirium resolved as his pain medications were weaned down. + +. +# Fever: The patient spiked a fever of 101.1 on [**2170-5-15**]. He was +empirically started on vancomycin because of concerning for a +PICC line infection. However, when his blood cultures came back +negative, and he defervesced promtly, the vancomycin was +discontinued after 3 days. +. +# Metastatic prostate cancer: with bone mets. Spine CT showed +extensive spine mets. Not able to tolerated spine MRI. PSA > 900 +from the 126 in [**Month (only) 547**]. After a discussion with his outpatient +oncologist, he was discharged with a plan for possible samarium +as outpatient. +. +# UTI: pan-sensitive Klebsiella. He was initially started on +ceftriaxone, which was switched to TMP/SMX when sensitivities +were available. He finished a 7 days of TMP/SMX. +. +# Anemia: During his last admission, AVM seen on EGD was +cauterized on [**2170-4-24**] during last admission. During this +admission he received 2 units of pRBCs in MICU, and his +hematocrit was stable after that. He was continued on PPI and +sucralfate. +. +# Psoriasis: continued on outpatient creams. +. +# Obstructive Sleep Apnea: continued on CPAP. +. +# Communication: [**First Name8 (NamePattern2) **] [**Known lastname **](wife/HCP)-([**Telephone/Fax (1) 36628**] +(h)/([**Telephone/Fax (1) 36629**] (c) +. +# Code: FULL + +Medications on Admission: +1. Lorazepam 1 mg PO Q6H +2. Docusate Sodium 100 mg PO BID +3. Senna 8.6 mg PO BID +4. Pantoprazole 40 mg PO BID +5. Sucralfate 1 gram PO QID +6. Lidocaine 5 % TD +7. Bisacodyl 10 mg PO QD +8. Nortriptyline 50 mg PO QD +9. Celecoxib 200 mg PO BID +10. Gabapentin 300 mg PO TID +11. Tylenol PRN +12. Enoxaparin 80 mg SC BID +13. OxyContin 80 mg PO TID +14. Hydromorphone 4-8 mg PO Q3-4 hours + + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +2. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO QID (4 times +a day). +Disp:*120 Tablet(s)* Refills:*2* +3. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated Sig: +One (1) Adhesive Patch, Medicated Topical DAILY (Daily). +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +4. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +5. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed for +constipation. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +6. Enoxaparin 120 mg/0.8 mL Syringe Sig: One [**Age over 90 **]y +(120) mg Subcutaneous Q12H (every 12 hours). +Disp:*qs 1 month's supply* Refills:*2* +7. Docusate Sodium 100 mg Capsule Sig: Two (2) Capsule PO BID (2 +times a day). +Disp:*120 Capsule(s)* Refills:*2* +8. Senna 8.6 mg Tablet Sig: Two (2) Tablet PO BID (2 times a +day) as needed for constipation. +Disp:*120 Tablet(s)* Refills:*0* +9. Clobetasol 0.05 % Cream Sig: One (1) Appl Topical [**Hospital1 **] (2 +times a day). +10. Hydromorphone 4 mg Tablet Sig: Three (3) Tablet PO Q2H +(every 2 hours) as needed for pain. +Disp:*qs 1 month's supply* Refills:*0* +11. Methadone 10 mg Tablet Sig: Two (2) Tablet PO Q6H (every 6 +hours). +Disp:*240 Tablet(s)* Refills:*2* +12. Gabapentin 100 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +13. Dulcolax 10 mg Suppository Sig: Ten (10) mg Rectal once a +day as needed for constipation. +Disp:*qs 1 month's supply* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary diagnosis: deep venous thrombosis + +Secondary diagnoses: metastatic prostate cancer, obstructive +sleep apnea, psoriasis + +Discharge Condition: +stable + +Discharge Instructions: +You presented to the [**Hospital1 18**] with leg pain and were found to have +a blood clot in your leg. You underwent a procedure to break up +the clot and received blood thinner. Please continue to take all +your medications, especially the enoxaparin (Lovenox), as +instructed. Please follow up with your physicians. + +If you develop worsening pain, difficulty breathing, fevers, +chills, chest pain, or any other concerning symptom, please go +to the nearest Emergency Room immediately. + +Followup Instructions: +* Oncology: Dr. [**Last Name (STitle) **], please call ([**Telephone/Fax (1) 31457**] to make a +follow-up appointment within 2 weeks. +* Primary care: Dr. [**Last Name (STitle) **], please call [**Telephone/Fax (1) 7477**] to maek a +follow-up appointment within 2 weeks. + + [**First Name4 (NamePattern1) 2946**] [**Last Name (NamePattern1) **] MD [**MD Number(1) 3218**] + +",175,2170-05-05 22:00:00,2170-05-21 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,"DVT, ANEMIA"," +52-year-old man with metastatic prostate cancer, not on active +chemo with recurrent dvts/pes despite anticoagulation, also with +recent gib, presented with le swelling, found to have rle dvt. +. +# dvt: the patient presented with worse clot burden. he was on +enoxaparin at home. anti-xa activity not checked on admission. +he underwent an ivc venogram and mechanical thrombolysis with +local tpa on [**2170-5-7**]. heparin was then discontinued, and he was +started on enoxaparin 120 mg [**hospital1 **] on [**2170-5-8**]. (the patient had +been on enoxaparin 80 mg [**hospital1 **] before this admission.) his anti-xa +activity was therapeutic. he was sent home with enoxaparin 120 +mg sc bid. +. +# chronic pain: the patient experienced significant pain from +bone metastases during this admission, requiring hydromorphone +pca. palliative care was consulted on pain management. his pain +gradually improved and he was discharged with methadone 20 mg po +qid and hydromorphone 12-24 mg po q2h prn as well as gabapentin. + +. +# intermittent delirium: most likely from high-dose pain meds. +his delirium resolved as his pain medications were weaned down. + +. +# fever: the patient spiked a fever of 101.1 on [**2170-5-15**]. he was +empirically started on vancomycin because of concerning for a +picc line infection. however, when his blood cultures came back +negative, and he defervesced promtly, the vancomycin was +discontinued after 3 days. +. +# metastatic prostate cancer: with bone mets. spine ct showed +extensive spine mets. not able to tolerated spine mri. psa > 900 +from the 126 in [**month (only) 547**]. after a discussion with his outpatient +oncologist, he was discharged with a plan for possible samarium +as outpatient. +. +# uti: pan-sensitive klebsiella. he was initially started on +ceftriaxone, which was switched to tmp/smx when sensitivities +were available. he finished a 7 days of tmp/smx. +. +# anemia: during his last admission, avm seen on egd was +cauterized on [**2170-4-24**] during last admission. during this +admission he received 2 units of prbcs in micu, and his +hematocrit was stable after that. he was continued on ppi and +sucralfate. +. +# psoriasis: continued on outpatient creams. +. +# obstructive sleep apnea: continued on cpap. +. +# communication: [**first name8 (namepattern2) **] [**known lastname **](wife/hcp)-([**telephone/fax (1) 36628**] +(h)/([**telephone/fax (1) 36629**] (c) +. +# code: full + + ","PRIMARY: [Acute venous embolism and thrombosis of deep vessels of proximal lower extremity] +SECONDARY: [Secondary malignant neoplasm of bone and bone marrow; Urinary tract infection, site not specified; Friedl?nder's bacillus infection in conditions classified elsewhere and of unspecified site; Delirium due to conditions classified elsewhere; Anemia, unspecified; Neoplasm related pain (acute) (chronic); Pure hypercholesterolemia; Obstructive sleep apnea (adult)(pediatric); Other psoriasis; Personal history of malignant neoplasm of prostate]" +26212,159674.0,22772,2190-01-22,22771,117561.0,2189-08-24,Discharge summary,"Admission Date: [**2189-8-20**] Discharge Date: [**2189-8-24**] + +Date of Birth: [**2133-11-10**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 348**] +Chief Complaint: +Perirectal abscess/ pain x 7 days. + +Major Surgical or Invasive Procedure: +I and D of abscess + +History of Present Illness: +55 year old cantonese speaking male , PMH of ESRD on tri weekly +dialysis, DM, HTN, who presents with perirectal pain and +perirectal mass x 7 days. + +Past Medical History: +-- HTN: difficult to control, multiple agents used +-- DM: with retinopathy, nephropathy +-- ESRD due to IgA nephropathy/DM +-- diabetic retinopathy- Blindness +-- R subclavian Thrombus [**2187**] - stopped anticoagulation in [**2187**] +-- Anemia of chronic disease +-- Hyperlipidemia +-- CAD - not an intervetional or CABG candidate. Cardiac +catheterization from [**2188-2-4**] showed 3VD with a 30% left +main, a diffusely diseased LAD with 80% mid stenosis, 90% +diagonal, 60% second diagonal, and 90% OM1. None suitable for +PCI or CABG. EF 60-70% TTE [**2188-10-14**] + +Social History: +Cantonese/Mandarin speaking, limited English, immigrated to the +US 10 yrs ago, currently lives with wife and 3 children, has +been blind for approx 3 years, has not worked recently; No +history of tobacco use, alcohol, or illicit drug use. Wife +injects insulin. + + +Family History: +No family history of DM, CAD, Stroke, HTN, or Renal Disease + +Physical Exam: +per surgery team +VS +Gen: Drowsy, hard to keep awake ( per wife is baseline state ). +Chest: Left dialysis catheter in Left subclavian vein. +CVS: RRR II/Vi Harsh systolic murmur at LSB and L 5th +intercostal space midclavicualr. No carotid bruits. +Pulm: CTAB no w/r/r +Abd: Soft NT/ ND + BS +Ext: No C/E bl +. +per icu team a day later: +VS: T 96.2; HR 68; BP 205/68; RR 22; SpO2 100% 3L NC +GEN: NAD, dyskinesia of mouth (lip smacking, tongue thrusting) +HEENT: mmm, poor dentition, small lesion on L side tongue, no +LAD, neck supple, no masses, blind, L eye: cloudy bloody cornea +no discernible pupil, R eye: small fixed pupil, injected +conjunctiva +CV: RRR, no M/R/G +LUNGS: CTA B, 100% 3L NC, episodes of panting +ABD: decreased bs, soft, ntnd +EXT: warm, dry, 2+ pedal and radial pulses, no edema or cyanosis +Perirectal area: packing is saturated with blood, edema +surrounding I/D site, very tender + + +Pertinent Results: +138 96 19 +-------------< 79 +3.4 29 6.0 +Ca: 8.6 Mg: 1.6 P: 2.4 D +. +WBC: 11.4 +HCT: 36.2 +PLT: 198 +. +PT: 14.3 PTT: 33.9 INR: 1.2 +. +CXR: FINDINGS: In comparison with the study of [**5-11**], there is +again enlargement of the cardiac silhouette, although less +prominent than on the previous study. There is again +engorgement of the pulmonary vessels consistent with substantial +elevation of pulmonary venous pressure. The costophrenic angles +have cleared, consistent with decreased pleural effusion + + +Brief Hospital Course: +Mr. [**Known lastname 724**] is a 55 year old man with a PMH significant for ESRD on +MWF HD, CAD, DM, anemia, poorly controlled HTN, and anemia +transferred from the surgical service for monitoring s/p +perirectal I/D. + +1. Perirectal Abscess: The patient was admitted for a perirectal +abscess status post I/D on [**8-19**]. Mr. [**Known lastname 724**] was initially treated +with ciprofloxacin and flagyl. After wound culture speciated out +as MRSA, vancomycin was added to the patient's antibiotic +therapy. Per Dr. [**Last Name (STitle) **] of surgery, antibiotic therapy will +need to be continued for 14 days (stop on [**9-5**]). The patient was +treated with oxycodone PRN for pain control, which he did not +require in the 48 hours prior to discharge. A follow-up +appointment was scheduled for the patient with Dr. [**Last Name (STitle) **] in +outpatient clinic in 2 weeks. + +2. HTN: After the patient's I/D procedure, he became +hypertensive with SBP >200 and was transferred to the [**Hospital Ward Name 332**] ICU +for closer monitoring. His home medications were continued and +he was also placed on a nitroglycerin drip which was continued +until his hemodialysis on [**8-21**], at which point he became +hypotensive and the nitroglycerin was discontinued. Upon +transfer to the medicine floor, his blood pressure remained +stable. At discharge, patient was continued on his home regimen +of labetolol, minoxidil, clonidine, imdur, and amlodipine. + +3. CAD: Patient's ASA and plavix was held for the I/D procedure. + At discharge, patient was resumed on all home medications +including ASA, plavix, losartan, labetolol, lisinopril. + +4. DM 2: Patient continued on 70/30 and RISS Q6H during his +hospital course. + +5. Hyperlipidemia: Patient continued on home statin therapy. + +6. ESRD: Patient on MWF hemodialysis, which was continued during +his hospital course. Last HD was on day of discharge ([**Month/Year (2) 766**]). +Nephrocaps continued during hospital course. The patient will +need vancomycin dosed per HD protocol. + +7. Anemia of chronic disease: On discharge, patient's HCT stable +and at baseline. + +Medications on Admission: +Allergies: NKDA + +Home meds (per OMR): +Atorvastatin 40mg po daily +Aspirin 325mg po daily +Clonidine patch +Epogen (2xper wk) +Hydralazine 50mg po daily +Insulin (NPH 10 units [**Hospital1 **]) +Lisinopril 40mg daily +Losartan 100mg daily +Metoprolol tartrate 150mg po bid +Minoxidil 2.5mb po bid +Amlodipine 10mg daily +Nephrocaps +Calcium 500mg po tid +Plavix 75mg po daily +Protonix 40mg po daily +Reglan 5mg q8h IV +Fluticasone 2 puffs IH [**Hospital1 **] + +Discharge Medications: +1. Lactulose 10 gram/15 mL Syrup Sig: Fifteen (15) ML PO DAILY +(Daily) as needed for constipation. +2. Amlodipine 5 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +3. Clonidine 0.2 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +4. Clopidogrel 75 mg Tablet Sig: One (1) Tablet PO once a day. +5. Atorvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +6. Labetalol 200 mg Tablet Sig: Four (4) Tablet PO TID (3 times +a day). +7. Minoxidil 2.5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +8. Isosorbide Dinitrate 10 mg Tablet Sig: Three (3) Tablet PO +TID (3 times a day). +9. Aspirin 325 mg Tablet Sig: One (1) Tablet PO once a day. +10. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO Before every +meal. +11. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO DAILY (Daily). +12. B Complex-Vitamin C-Folic Acid 1 mg Capsule Sig: One (1) Cap +PO DAILY (Daily). +13. Fluticasone 50 mcg/Actuation Disk with Device Sig: Two (2) +puffs Inhalation twice a day. +14. Calcium Carbonate 500 mg Tablet, Chewable Sig: Two (2) +Tablet, Chewable PO TID (3 times a day) as needed. +15. Insulin NPH & Regular Human 100 unit/mL (70-30) Cartridge +Sig: 8 units in the morning and 6 units at night . Subcutaneous +daily. +16. Losartan 100 mg Tablet Sig: One (1) Tablet PO once a day. +17. Metronidazole 250 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 12 days: Stop on [**9-5**]. +Disp:*36 Tablet(s)* Refills:*0* +18. Ciprofloxacin 500 mg Tablet Sig: One (1) Tablet PO Q24H +(every 24 hours) for 12 days: STOP ON [**9-5**]. +Disp:*12 Tablet(s)* Refills:*0* +19. Vancomycin in Dextrose 1 gram/200 mL Piggyback Sig: One (1) +gram Intravenous HD PROTOCOL (HD Protochol) for 12 days: STOP ON +[**9-5**]. gram +20. Insulin NPH & Regular Human 100 unit/mL (70-30) Cartridge +Sig: 8 units in the AM and 6 units in the PM Subcutaneous twice +a day. +21. Calcium Carbonate 500 mg Tablet, Chewable Sig: Two (2) +Tablet, Chewable PO TID (3 times a day). +22. Outpatient Lab Work +Vancomycin trough to be drawn on Friday ([**8-28**]) prior to +hemodialysis. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital6 1952**], [**Location (un) 86**] + +Discharge Diagnosis: +Primary +1. Perirectal abscess +2. Hypertension + +Secondary +Diabetes +ESRD qMWF due to IgA nephropathy/DM +Diabetic retinopathy +R subclavian Thrombus [**2187**] - stopped anticoagulation in [**2187**] +Anemia of chronic disease +Hyperlipidemia +CAD + + +Discharge Condition: +Patient was discharged in stable condition. + + +Discharge Instructions: +1. You were admitted for a perirectal abscess, which was +surgically drained. You will need to take antibiotics for a +total of 14 days (STOP ON [**9-5**]). Your antibiotic regimen is: +Vancomycin 1000mg per HD protocol +Flagyl 250mg po TID (to be given after hemodialysis) +Ciprofloxacin 500 mg by mouth every 24 hours (to be given after +hemodialysis) + +2. You will need to have a blood test (vancomycin trough) drawn +on Friday (8/285) prior to hemodialysis. + +3. You should resume all of your home medications as prior to +admission. It is important that you take all of your medications +as prescribed. + +4. You have a follow-up appointment with the surgeon as listed +below. It is very important that you make all of your doctors +[**Name5 (PTitle) 4314**]. + +5. If you develop a fever, chest pain, shortness of breath, or +other concerning symptoms, you should contact your PCP or go to +the local Emergency Department immediately. + +Followup Instructions: +You are scheduled for a follow-up appointment with Dr. [**Last Name (STitle) **] +of surgery on [**2189-9-3**] at 4pm at [**Street Address(2) 1126**] in [**Location (un) **], +MA. + +Please follow-up with your PCP, [**Last Name (NamePattern4) **]. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] in [**2-4**] +weeks. You can [**Month/Day (2) **] an appointment by calling ([**Telephone/Fax (1) 58911**]. + +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 12902**], MD Phone:[**Telephone/Fax (1) 253**] +Date/Time:[**2189-11-19**] 10:30 + +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], [**Name Initial (NameIs) **].D. Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2190-4-6**] 11:20 + + + +Completed by:[**2189-8-24**]",151,2189-08-20 10:06:00,2189-08-24 16:30:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOME HEALTH CARE,PERI RECTAL ABSCESS," +mr. [**known lastname 724**] is a 55 year old man with a pmh significant for esrd on +mwf hd, cad, dm, anemia, poorly controlled htn, and anemia +transferred from the surgical service for monitoring s/p +perirectal i/d. + +1. perirectal abscess: the patient was admitted for a perirectal +abscess status post i/d on [**8-19**]. mr. [**known lastname 724**] was initially treated +with ciprofloxacin and flagyl. after wound culture speciated out +as mrsa, vancomycin was added to the patients antibiotic +therapy. per dr. [**last name (stitle) **] of surgery, antibiotic therapy will +need to be continued for 14 days (stop on [**9-5**]). the patient was +treated with oxycodone prn for pain control, which he did not +require in the 48 hours prior to discharge. a follow-up +appointment was scheduled for the patient with dr. [**last name (stitle) **] in +outpatient clinic in 2 weeks. + +2. htn: after the patients i/d procedure, he became +hypertensive with sbp >200 and was transferred to the [**hospital ward name 332**] icu +for closer monitoring. his home medications were continued and +he was also placed on a nitroglycerin drip which was continued +until his hemodialysis on [**8-21**], at which point he became +hypotensive and the nitroglycerin was discontinued. upon +transfer to the medicine floor, his blood pressure remained +stable. at discharge, patient was continued on his home regimen +of labetolol, minoxidil, clonidine, imdur, and amlodipine. + +3. cad: patients asa and plavix was held for the i/d procedure. + at discharge, patient was resumed on all home medications +including asa, plavix, losartan, labetolol, lisinopril. + +4. dm 2: patient continued on 70/30 and riss q6h during his +hospital course. + +5. hyperlipidemia: patient continued on home statin therapy. + +6. esrd: patient on mwf hemodialysis, which was continued during +his hospital course. last hd was on day of discharge ([**month/year (2) 766**]). +nephrocaps continued during hospital course. the patient will +need vancomycin dosed per hd protocol. + +7. anemia of chronic disease: on discharge, patients hct stable +and at baseline. + + ","PRIMARY: [Abscess of anal and rectal regions] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, malignant, with chronic kidney disease stage V or end stage renal disease; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled; Background diabetic retinopathy; Anemia in chronic kidney disease]" +26901,179730.0,24113,2185-10-17,24112,160675.0,2185-07-04,Discharge summary,"Admission Date: [**2185-7-1**] Discharge Date: [**2185-7-4**] + +Date of Birth: [**2160-11-6**] Sex: M + +Service: MEDICINE + +Allergies: +Codeine + +Attending:[**First Name3 (LF) 1257**] +Chief Complaint: +DKA + +Major Surgical or Invasive Procedure: +Femoral line placement + +History of Present Illness: +Mr [**Known lastname 61289**] is a 24M with poorly-controlled DM who presents with +DKA. +He was well until approx 4d ago when he developed a +nonproductive cough, along with chills and sweats and some nasal +congestion but no fevers. The evening prior to admission he +developed periumbilical abdominal discomfort accompanied by +nausea and non-bloody vomiting. Has chronic constipation with +BMs usually 1x week, had 4 BMs the day prior to presentation. +His PO intake was poor. He last took his insulin approximately +24h prior to presentation. Has been making urine, but no +dysuria, hematuria, no NSAID use. Reports low back pain similar +to prior. Denies metalic taste, pruritis, dyspnea. +. +In the emergency department, vitals were 98.3 104 154/82 16 100% +on RA. On exam, writhing in abdominal pain. He was given zofran, +ativan, insulin (10 units x2 sq) currently on 7units/hr drip. +CXR showed a LLL pna and he was given levofloxacin. Had a +femoral line placed for access, 22 wrist PIV. Given 4L of normal +saline. Renal was not contact[**Name (NI) **]. HR low 100's BP 160's RR 22. + + +Past Medical History: +- Diabetes mellitus, type I. Diagnosed in [**2162**]. Poorly +controlled with past DKA. Complicated with retinopathy, +nephropathy +- Hypertension, poorly controlled +- Chronic kidney disease +- Chronic constipation + + +Social History: +Lives with aunt in [**Location (un) 686**]. Smokes 2 packs per week since age + +16. Denies recent alcohol use. Denies illicit drug use, now or +in the past. + + +Family History: +Father, grandmother with diabetes mellitus. No relatives +currently on dialysis. + + +Physical Exam: +Vitals 97.2 94 138/87 12 95% on RA +General Lying in bed appearing comfortable +HEENT Sclera anicteric, MMM +Neck Supple no JVD +Pulm Lungs clear bilaterally, no rales or wheezing +CV Regular S1 S2 no m/r/g +Abd Soft nontender +bowel sounds +Extrem Warm no edema palpable pulses +Neuro Sleepy but arousable, responds to commands, answering +appropriately, moving all extremities without focal deficits +Derm No rash +Lines/tubes/drains + + +Brief Hospital Course: +24 year old man with poorly controlled DM and HTN with ESRD not +yet on HD presents with DKA in setting of insulin noncompliance +and an underlying viral pneumonia versus viral URI. He was +admitted to the ICU and started on an insulin drip. The anion +gap closed and he was transitioned to glargine in the morning +(22 units) and maintained on a sliding scale. He was followed by +the [**Last Name (un) 387**] consult team while hospitalized and will see them as +an outpatient this week. He had abnormal chest film along with +cough and chills. He was started on empiric levofloxacin, +however, his flu swab came back positive for influenza A and the +antibiotics were discontinued. The influenza was not H1N1 by +state lab testing. He was afebrile for 24 hours prior to +discharge. We found normocytic anemia likely from CKD. Iron +studies were sent and were pending at the time of discharge. +They will be followed up by the [**Hospital **] clinic and he will likely +be started on epoetin as an outpatient. He was discharged on +empiric iron. + + +Medications on Admission: +metoprolol 50mg [**Hospital1 **] +amlodipine 10mg daily +simvastatin 20mg daily +hydralazine 50mg tid +aranesp 40mcg qweek +insulin galrgine 20 units qhs +insulin humalog sliding scale +miralax +senna + +Discharge Medications: +1. Metoprolol Tartrate 50 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +2. Amlodipine 5 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +3. Hydralazine 25 mg Tablet Sig: Two (2) Tablet PO Q8H (every 8 +hours). +4. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +5. Metoclopramide 10 mg Tablet Sig: 0.5 Tablet PO QIDACHS (4 +times a day (before meals and at bedtime)). +Disp:*30 Tablet(s)* Refills:*2* +6. Insulin Glargine 100 unit/mL Solution Sig: Twenty Two (22) +units Subcutaneous once a day. +7. Insulin Lispro 100 unit/mL Solution Sig: AS DIR Subcutaneous +four times a day: As needed per sliding scale. +8. Iron (Ferrous Sulfate) 325 mg (65 mg Iron) Tablet Sig: One +(1) Tablet PO twice a day. +Disp:*60 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Diabetic Keto-acidosis +Influenza A +Chronic Kidney Disease +Anemia of Chronic Disease + + +Discharge Condition: +Afebrile, hemodynamically stable. + + +Discharge Instructions: +You were admitted to the hospital with the flu. Because you were +sick your diabetes was not in good control and you needed +insulin through an IV for a couple of days. You have been able +to eat and take your insulin now and should continue doing this +when you are discharged. + +Medication changes: +CHANGE: Glargine to 22units at breakfast time +START: Reglan 5mg by mouth with meals and at bedtime +START: Iron 325mg by mouth twice daily + +Please come back to the hospital or call your doctor if you have +fevers, chills, abdominal pain, nausea, vomiting, inability to +take your insulin, inability to eat, chest pain, back pain, +rash, or any other concerning symptoms. + +Followup Instructions: +Please follow up with your primary care provider, [**Last Name (NamePattern4) **]. [**Last Name (STitle) 14166**] +([**Telephone/Fax (1) 14167**]) in the next 1-2 weeks. + +Please follow up with Dr.[**Name (NI) 33126**] nurse [**First Name8 (NamePattern2) 3639**] [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **]-[**Doctor Last Name **] ([**Telephone/Fax (1) 3637**]) on [**2185-7-7**] at 1:00pm. + + + +Completed by:[**2185-7-4**]",105,2185-07-01 15:16:00,2185-07-04 17:41:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,PNEUMONIA;DIABETIC KETOACIDOSIS," +24 year old man with poorly controlled dm and htn with esrd not +yet on hd presents with dka in setting of insulin noncompliance +and an underlying viral pneumonia versus viral uri. he was +admitted to the icu and started on an insulin drip. the anion +gap closed and he was transitioned to glargine in the morning +(22 units) and maintained on a sliding scale. he was followed by +the [**last name (un) 387**] consult team while hospitalized and will see them as +an outpatient this week. he had abnormal chest film along with +cough and chills. he was started on empiric levofloxacin, +however, his flu swab came back positive for influenza a and the +antibiotics were discontinued. the influenza was not h1n1 by +state lab testing. he was afebrile for 24 hours prior to +discharge. we found normocytic anemia likely from ckd. iron +studies were sent and were pending at the time of discharge. +they will be followed up by the [**hospital **] clinic and he will likely +be started on epoetin as an outpatient. he was discharged on +empiric iron. + + + ","PRIMARY: [Diabetes with ketoacidosis, type I [juvenile type], uncontrolled] +SECONDARY: [Influenza with pneumonia; Chronic kidney disease, Stage IV (severe); Acute kidney failure, unspecified; Diabetes with ophthalmic manifestations, type I [juvenile type], uncontrolled; Background diabetic retinopathy; Diabetes with renal manifestations, type I [juvenile type], uncontrolled; Nephritis and nephropathy, not specified as acute or chronic, in diseases classified elsewhere; Constipation, unspecified; Anemia in chronic kidney disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Gastroparesis; Personal history of noncompliance with medical treatment, presenting hazards to health]" +27790,162585.0,18577,2113-08-18,18576,127130.0,2113-07-21,Discharge summary,"Admission Date: [**2113-7-12**] Discharge Date: [**2113-7-21**] + + +Service: NEUROSURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1854**] +Chief Complaint: +The patient's chief complaint is of increasing ataxia while at +rehab facility. + +Major Surgical or Invasive Procedure: +1. [**2114-7-14**] Left Craniotomy for Subdural Hematoma + + +History of Present Illness: +Patient is a 85M with a PMH significant for atrial fibrillation +presently treated with a pacemaker and aspirin therapy. He +reports having been on Coumadin at one point in time, but not +for a while now. He returns to the ED this afternoon with chief +complaint of increasing ataxia while at rehab facility. He was +transferred back to [**Hospital1 18**] for re-evaluation for ? recurrance of +SDH. + +Past Medical History: +PMHx: +1. Atrial Fibrillation requiring the use of a pacemaker +2. Prostate CA presently undergoing work-up for cryotherapy. +3. s/p Bilateral cataract surgery + +Social History: +Social Hx: resides at home alone in [**Location (un) 51029**] + + +Family History: +Family Hx: non-contributory. + +Physical Exam: +O: T: 98.1 BP:157/63 HR:59 RR:16 O2Sats: 98% RA +Gen: WD/WN, comfortable, NAD. +HEENT:normocephalic, atraumatic +Pupils: surgically irregular, minimally reactive +EOMs: intact +Extrem: Warm and well-perfused. +Neuro: +Mental status: Awake and alert, cooperative with exam, normal +affect. +Orientation: Oriented to person, place, and date. +Recall: [**2-20**] objects at 5 minutes. +Language: Speech fluent with good comprehension and repetition. +Naming intact. No dysarthria or paraphasic errors. + +Cranial Nerves: +I: Not tested +II: Pupils are surgically asymmetric and minimally reactive to +light, 3mm bilaterally. Visual fields are full to confrontation. + +III, IV, VI: Extraocular movements intact bilaterally without +nystagmus. +V, VII: Facial strength and sensation intact and symmetric. +VIII: Hearing intact to voice. +IX, X: Palatal elevation symmetrical. +[**Doctor First Name 81**]: Sternocleidomastoid and trapezius normal bilaterally. +XII: Tongue midline without fasciculations. + +Motor: Normal bulk and tone bilaterally. No abnormal movements, +tremors. Strength full power [**4-24**] throughout. Slight right +pronator drift. Right sided dysmetria. + +Sensation: Intact to light touch, propioception. + +Reflexes: B T Br Pa Ac +Right 2 2 2 2 2 +Left 2 2 2 2 2 + +Coordination: normal on finger-nose-finger + +Pertinent Results: +Speech & Swallow Evaluation: +RECOMMENDATIONS: +1. PO diet: regular solids, nectar thick liquids. +2. PO meds whole with nectar thick liquids. +3. 1:1 supervision with meals to maintain aspiration precautions +and assist with feeding. Encourage pt to alternate bites with +sips to clear. +4. Please reconsult if there are concerns for aspiration on this +diet and a videoswallow study can be performed. +5. Repeat swallow evaluation early next week here or at rehab. + +Pre-operative HCT: +IMPRESSION: Increased size of left cerebral convexity subdural +hemorrhage, +with new hyperdensity suggestive of rebleeding. 8-mm rightward +subfalcine +herniation. + +Post-operative HCT: +IMPRESSION: S/p left frontal craniotomy with interval decrease +in the size of the subdural collection. Partial improvement in +associated mass effect. + +Labs: +[**2113-7-21**] 06:44AM BLOOD WBC-7.8 RBC-3.05* Hgb-9.6* Hct-28.1* +MCV-92 MCH-31.6 MCHC-34.3 RDW-13.1 Plt Ct-269 + +[**2113-7-21**] 06:44AM BLOOD Glucose-107* UreaN-17 Creat-0.5 Na-137 +K-3.9 Cl-106 HCO3-24 AnGap-11 + +[**2113-7-21**] 06:44AM BLOOD Calcium-8.1* Phos-2.5* Mg-2.2 + +Brief Hospital Course: +The patient on [**7-14**] was brought to the OR for a craniotomy for +a large left SDH. His pressure was kept below 140 and after the +procedure his stayed overnight in PACU and on [**7-15**] his was +transferred to stepdown. He began treatment for a UTI with +levaquin. A speech and swallow evaluation on [**7-17**], and dietary +adjustments were made accordingly. Due to the nature of his +urine culture, he was MRSA screened and finalized as negative on +[**2113-7-21**]. His neurlogical examination has been stable since his +operative intervention, and determined to be appropriate for +rehabilitation. + +Medications on Admission: +1. ASA 81mg daily +2. Folic Acid 400mcg daily +3. Calcium 500mg daily +4. Casodex 50mg daily +5. Actonel 35mg weekly +6. Tagamet 300mg daily +7. Metamucil daily +8. Dilantin 100mg TID + + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +2. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +3. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Bicalutamide 50 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +7. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +8. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +9. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed. +10. Ipratropium Bromide 0.02 % Solution Sig: One (1) Inhalation +Q6H (every 6 hours) as needed. +11. Calcium Carbonate 500 mg Tablet, Chewable Sig: Two (2) +Tablet, Chewable PO DAILY (Daily). +12. Phenytoin Sodium Extended 100 mg Capsule Sig: Three (3) +Capsule PO BID (2 times a day). +13. Sodium Chloride 0.9% Flush 3 mL IV PRN line flush +Peripheral line: Flush with 3 mL Normal Saline every 8 hours and +PRN. +14. Levaquin 500 mg Tablet Sig: One (1) Tablet PO once a day for +10 days. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 979**] - [**Location (un) 246**] + +Discharge Diagnosis: +Left Subdural Hematoma +Urinary tract infection +Post-surgical urinary retention + + +Discharge Condition: +Neurologically Stable + + +Discharge Instructions: +General Instructions + +?????? Have a friend/family member check your incision daily for +signs of infection. +?????? Take your pain medicine as prescribed. +?????? Exercise should be limited to walking; no lifting, straining, +or excessive bending. +?????? You may wash your hair only after sutures have been removed. +?????? You may shower before this time using a shower cap to cover +your head. +?????? Increase your intake of fluids and fiber, as narcotic pain +medicine can cause constipation. We generally recommend taking +an over the counter stool softener, such as Docusate (Colace) +while taking narcotic pain medication. +?????? Unless directed by your doctor, do not take any +anti-inflammatory medicines such as Motrin, Aspirin, Advil, and +Ibuprofen etc. +?????? You have been prescribed an anti-seizure medicine, take it as +prescribed and follow up with laboratory blood drawing as +ordered. +?????? Clearance to drive and return to work will be addressed at +your post-operative office visit. + +CALL YOUR SURGEON IMMEDIATELY IF YOU EXPERIENCE ANY OF THE +FOLLOWING + +?????? New onset of tremors or seizures. +?????? Any confusion or change in mental status. +?????? Any numbness, tingling, weakness in your extremities. +?????? Pain or headache that is continually increasing, or not +relieved by pain medication. +?????? Any signs of infection at the wound site: redness, swelling, +tenderness, or drainage. +?????? Fever greater than or equal to 101?????? F. + + +Followup Instructions: +Follow-Up Appointment Instructions + +??????Please return to the office in 10 days for removal of your +sutures. This may also be done at the rehab facility. +??????Please call ([**Telephone/Fax (1) 88**] to schedule an appointment with Dr. +[**Last Name (STitle) **]/[**Doctor Last Name **], to be seen in 4 weeks. +??????You will need a CT scan of the brain without contrast. + + + +Completed by:[**2113-7-21**]",28,2113-07-12 17:36:00,2113-07-21 13:20:00,EMERGENCY,EMERGENCY ROOM ADMIT,REHAB/DISTINCT PART HOSP,ACUTE SUBDURAL HEMATOMA," +the patient on [**7-14**] was brought to the or for a craniotomy for +a large left sdh. his pressure was kept below 140 and after the +procedure his stayed overnight in pacu and on [**7-15**] his was +transferred to stepdown. he began treatment for a uti with +levaquin. a speech and swallow evaluation on [**7-17**], and dietary +adjustments were made accordingly. due to the nature of his +urine culture, he was mrsa screened and finalized as negative on +[**2113-7-21**]. his neurlogical examination has been stable since his +operative intervention, and determined to be appropriate for +rehabilitation. + + ","PRIMARY: [Subdural hemorrhage] +SECONDARY: [Subdural hemorrhage following injury without mention of open intracranial wound, with no loss of consciousness; Urinary tract infection, site not specified; Compression of brain; Atrial fibrillation; Cardiac pacemaker in situ; Malignant neoplasm of prostate]" +27960,179767.0,15207,2196-01-28,15205,119407.0,2195-09-04,Discharge summary,"Admission Date: [**2195-9-3**] Discharge Date: [**2195-9-4**] + +Date of Birth: [**2171-11-13**] Sex: F + +Service: MEDICINE + +Allergies: +Vicodin / Augmentin / Diflucan + +Attending:[**First Name3 (LF) 3556**] +Chief Complaint: +angioedema vs anaphylaxis + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +History of Present Illness: 23F PMH idiopathic chronic urticaria +and angioedema, asthma followed by allergy presenting with +tongue swelling and dysphagia starting at 7:45 am soon after +awakening. Denies shortness of breath, wheezing, dizziness, +urticaria, flushing, pruritus. The patient is not taking any new +medications and denies new exposures or insect bites prior to +this episode. The patient does admit to smoking one cigarette +the night prior to admission. The patient took benadryl, +ranitidine, loratidine and a shot of her Epi-Pen prior to +presenting to the ED. In the ED, the patient's vital signs were +T 98.1, P 64, BP 133/61, RR 20, O2sat 100%RA. The patient was +evaluated by ENT with laryngoscope showing oropharyngeal +swelling but no swelling of the vocal cords. The patient was +given a dose of methylprednisolone 125 mg IV. The patient feels +symptomatic improvement in tongue swelling and dysphagia on +admission. +. +Of note, the patient has had chronic urticaria and angioedema +since Cesearean section performed [**2195-6-7**] for failure to +progress after 30 hour labor; done under epidural. The patient +has seubsequently been seen in the ED multiple times for facial +and tongue swelling. The patient was given prednisone 60 mg x 5 +days [**2195-8-11**] for isolated upper lip swelling. +. +Review of systems: As above. Negative for fevers, chills, chest +pain, abdominal pain, nausea, vomiting, diarrhea, melena, BRBPR, +dysuria, hematuria. The patient has not had a menstrual cycle +since giving birth as above. + + +Past Medical History: +1. Asthma +2. Seasonal allergies +3. Status post cholecystectomy ([**4-30**]) +4. Status post medical abortion of 16 week gestation in [**8-2**]. +5. Status post motor vehicle accident in 8th grade. She was +recommended to wear an LSO brace for stability, however, she +refused. She has not had porblems with back pain though. + +Social History: +She lives at home with her father, twin sister, and two-month +old child. She works as an administrator at [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +International. Rare social tobacco use. She denies alcohol and +IV drug use. + +Family History: + Mother - age 53, seizures, DM +Father - age 55, DM, HTN +2 brothers - asthma +2 sisters - 1 identical twin w/ asthma; 1 murmur, arrhythmias + + +Physical Exam: +Vitals: AF P:91 BP:129/74 RR:12 O2sat:100%RA +General: Well appearing female in no acute distress, speaking +full sentences without stridor. +HEENT: Pupils equal and reactive, extraoccular movements intact, +tongue edematous, OP edematous but no signs of airway +compromise, no edema of lips or ocular membranes, moist mucous +membranes. +Neck: Supple without lymphadenopathy or edema. +Cardiac: Regular rate and rhythm without murmurs, rubs, or +gallops. +Pulmonary: Clear to auscultation bilaterally, no wheezes, rales, +or rhonchi. +Abdomen: Normoactive bowel sounds, soft, obese, no rebound or +guarding, well-healed Cesarean scar. +Extremities: Warm and well perfused without cyanosis or edema. +Neurological: Cranial nerves II through XII intact. Gait +narrow-based and steady. + + +Pertinent Results: +[**2195-9-3**] 10:25AM GLUCOSE-98 UREA N-12 CREAT-0.7 SODIUM-140 +POTASSIUM-3.8 CHLORIDE-107 TOTAL CO2-25 ANION GAP-12 +[**2195-9-3**] 10:25AM MAGNESIUM-2.2 IRON-15* +[**2195-9-3**] 10:25AM calTIBC-464 FERRITIN-5.1* TRF-357 +[**2195-9-3**] 10:25AM WBC-8.0 RBC-4.03* HGB-9.4* HCT-29.7* MCV-74* +MCH-23.3* MCHC-31.6 RDW-17.2* +[**2195-9-3**] 10:25AM NEUTS-80.1* LYMPHS-17.3* MONOS-1.2* EOS-1.1 +BASOS-0.3 +[**2195-9-3**] 10:25AM PLT COUNT-390 +[**2195-9-3**] 09:40AM GLUCOSE-102 UREA N-13 CREAT-0.8 SODIUM-138 +POTASSIUM-4.8 CHLORIDE-106 TOTAL CO2-22 ANION GAP-15 +[**2195-9-3**] 09:40AM estGFR-Using this +CHEST (PORTABLE AP) + +Reason: Evaluate for pathology. + +[**Hospital 93**] MEDICAL CONDITION: +23 year old woman with chronic urticaria, angioedema p/w OP +swelling. +REASON FOR THIS EXAMINATION: +Evaluate for pathology. +CHEST AP PORTABLE SINGLE VIEW. + +INDICATION: Chronic urticaria, angioedema. Evaluate for possible +pulmonary pathology. + +FINDINGS: AP single view of the chest has been obtained with +patient in sitting upright position and analysis is performed in +comparison with a preceding PA and lateral chest examination of +[**2195-8-19**]. No significant interval change has occurred in +the previously as normal identified chest examination. Heart +size is within normal limits considering AP technique. +Noteworthy is considerable adiposity in the form of prominent +soft tissue surrounding the thorax. + +IMPRESSION: No new chest abnormality on portable AP single view +chest examination in comparison with normal previous study of +[**10-19**]. + + +Brief Hospital Course: +Pt was treated for an acute episode of angioedema with a +question of anaphylaxis. The patient has a history of presumed +idiopathic chronic urticaria and angioedema and has no no known +precipitants to this episode. The patient is followed by Dr. +[**Last Name (STitle) **] from allergy. The patient's vital signs were stable and +examination was siginificant for tongue swelling but no signs of +airway compromise. The patient took benadryl, ranitidine, +famotidine and a shot of her Epi-Pen prior to presenting to the +ED. The patient was given a dose of methylprednisolone 125 mg IV +was continued on benadryl, ranitidine, loratidine. Pt was +monitored overnight in the ICU and no further episodes of airway +compromise or angioedema. We contact[**Name (NI) **] her outpatient allergist +who felt this patient most likely had acute angioedema. +Aftrer 24 hours in the ICU, the patient was discharged home in +stable condition. + +Medications on Admission: +Doxepin 25 mg QHS +Loratidine 10 mg QD +Ranitidine 300 mg QD +Benadryl 50 mg [**Hospital1 **] +Epi-Pen 0.3 mg/0.3 mL Syringe PRN + + +Discharge Medications: +1. Doxepin 25 mg Capsule Sig: One (1) Capsule PO HS (at +bedtime). +2. Ranitidine HCl 150 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +3. Loratadine 10 mg Tablet Sig: One (1) Tablet PO once a day. +4. Diphenhydramine HCl 25 mg Capsule Sig: Two (2) Capsule PO BID +(2 times a day). +5. EpiPen 0.3 mg/0.3 mL Syringe Sig: One (1) Intramuscular once +a day as needed for allergy symptoms. +Disp:*2 syringe* Refills:*0* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +1. Angioedema versus anaphylaxis. +2. Idiopathic chronic urticaria and angioedema. +3. Chronic iron-deficiency anemia. +. +Secondary: +1. Seasonal allergies. +2. Asthma, in remission; one hospitalization but never +intubated. +3. Gastroesophageal reflux disease. +4. Status post cholecystectomy 5/[**2190**]. +5. Status post medical abortion of 16 week gestation in 8/[**2192**]. + +6. Status post motor vehicle accident in 8th grade. + + +Discharge Condition: +Afebrile, vital signs stable. No signs of airway compromise. + + +Discharge Instructions: +You were admitted with another episode of angioedema and tongue +swelling. It is very important that you take your medications +and keep an Epi-Pen at home. Please follow-up with your +allergist as below. +. +Please follow-up with your primary care physician regarding your +[**Name9 (PRE) 44267**] anemia, likely due to blood loss from menstrual +cycles. +. +Please contact a physician if you experience fevers, chills, +tongue swelling or other angioedema, shortness of breath, or any +other concerning symptoms. +. +Please take your medications as prescribed. There were no +changes to your medications. +. +Please keep your follow-up appointments as below. + +Followup Instructions: +Previously scheduled appointments: +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 30764**], MD Phone:[**Telephone/Fax (1) 1723**] +Date/Time:[**2195-9-23**] 2:45 +. +Please call your primary care physician, [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], +at [**Telephone/Fax (1) 250**] to schedule an appointment within two weeks. + + + [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 3559**] MD, [**MD Number(3) 3560**] + +",146,2195-09-03 09:53:00,2195-09-04 09:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALLERGIC REACTION," +pt was treated for an acute episode of angioedema with a +question of anaphylaxis. the patient has a history of presumed +idiopathic chronic urticaria and angioedema and has no no known +precipitants to this episode. the patient is followed by dr. +[**last name (stitle) **] from allergy. the patients vital signs were stable and +examination was siginificant for tongue swelling but no signs of +airway compromise. the patient took benadryl, ranitidine, +famotidine and a shot of her epi-pen prior to presenting to the +ed. the patient was given a dose of methylprednisolone 125 mg iv +was continued on benadryl, ranitidine, loratidine. pt was +monitored overnight in the icu and no further episodes of airway +compromise or angioedema. we contact[**name (ni) **] her outpatient allergist +who felt this patient most likely had acute angioedema. +aftrer 24 hours in the icu, the patient was discharged home in +stable condition. + + ","PRIMARY: [Angioneurotic edema, not elsewhere classified] +SECONDARY: [Iron deficiency anemia, unspecified; Asthma, unspecified type, unspecified; Esophageal reflux; Unspecified accident]" +27960,179767.0,15207,2196-01-28,15206,191411.0,2195-11-26,Discharge summary,"Admission Date: [**2195-11-21**] Discharge Date: [**2195-11-26**] + +Date of Birth: [**2171-11-13**] Sex: F + +Service: MEDICINE + +Allergies: +Vicodin / Augmentin / Diflucan / Amoxicillin + +Attending:[**First Name3 (LF) 3561**] +Chief Complaint: +Tongue Swelling + +Major Surgical or Invasive Procedure: +Endotracheal intubation + +History of Present Illness: +24 y.o. female with history of idiopathic urticaria and +angioedema with multiple hospitalizations for tongue swelling +who presented to the ED this morning with tongue swelling. +Patient reportedly woke up from sleep short of breath at which +time she noticed her tongue swelling. It is unclear if there was +any direct precipitant. EMS was notified and she was given +Epinephrine in the field x 1 with no effect. Once in the ER, she +was noted to have severe left-sided tongue swelling and received +an additional dose of Epinephrine as well as Famotidine, +Benadryl and Solu-medrol with no improvement in symptoms after +10 minutes. She was then electively intubated to protect her +airway and admitted to the MICU for further management. +. +With regards to the patient's tongue swelling, she began +experiencing symptoms of frequent hives and tongue swelling +after a cesarian section in [**Month (only) **] of this year. She has no clear +triggers though the patient's father has noticed that the +episodes seem to coincide with periods of high emotional stress. +She has been followed in allergy/immunology and is felt to have +idiopathic urticaria and angioedema and uses an Epinephrine pen, +approximately once every week for these symptoms. She +additionally has been on Prednisone tapers subsequent to her +multiple hospitalizations, which of note have not resulted in an +intubation until now. Other pertinent work-up for this condition +includes an investigation into atopy and the patient has no +history of frequent infections, immune disorders, eczema, +contact allergies, reactions to foods, meds, latex, insect +stings. She has an identical twin sister who has not had any +such reactions nor has anyone in her immediate family. C4 levels +checked in the past have been WNL, with respect to a work-up for +C1 esterase deficiency. + +Past Medical History: +1. Chronic urticaria and angioedemea since C-section done on +[**6-4**] for failure to progress after 30 hour labor +2. Asthma +3. Seasonal allergies +4. Status post cholecystectomy ([**4-30**]) + +Social History: +Lives with father and siblings and has a 5 month old son. +[**Name (NI) 6961**] are separated and there appears to be some tension +between mother and children as mother has a psychiatric illness. +Per father he and patient have also recently had a tumultuous +relationship and are currently not on speaking terms. Reportedly +infrequent alcohol or tobacco use and no IV drugs. + + +Family History: +Father with seasonal allergies. Otherwise, no history of related +urticaria, angioedema. + +Physical Exam: +Vitals: T-96.0 , BP-115/46, HR-81, RR-14, O2-100% AC 550/14/.[**5-2**] +General: Sedated, intubated, NAD +HEENT: NC/AT; PERRLA, EOMI; Tongue notably swollen, mostly on +left +CV: S1, S2 nl, no m/r/g appreciated +Lungs: CTAB +Abd: Soft, NT, ND, + BS +Ext: No c/c/c +Neuro: Grossly intact, but pt. is sedated. She appropriately +withdraws from pain and can open eyes on request +Skin: No urticaria or other rashes + + +Pertinent Results: +CXR ([**10-21**]): Endotracheal tube in satisfactory position 5 cm +above the carina. No acute cardiopulmonary process. +[**2195-11-21**] 11:25AM BLOOD WBC-10.6 RBC-4.34 Hgb-10.5* Hct-32.9* +MCV-76* MCH-24.3* MCHC-32.0 RDW-17.1* Plt Ct-523* +[**2195-11-23**] 04:24AM BLOOD WBC-6.7 RBC-2.62*# Hgb-6.2*# Hct-23.9*# +MCV-91# MCH-23.7* MCHC-26.0*# RDW-17.5* Plt Ct-317 +[**2195-11-23**] 06:08AM BLOOD WBC-11.4*# RBC-4.24# Hgb-10.4*# +Hct-32.7*# MCV-77*# MCH-24.4* MCHC-31.8# RDW-18.3* Plt Ct-566*# +[**2195-11-24**] 03:32AM BLOOD WBC-16.9* RBC-3.85* Hgb-9.4* Hct-29.2* +MCV-76* MCH-24.5* MCHC-32.3 RDW-17.8* Plt Ct-426 +[**2195-11-26**] 03:24AM BLOOD WBC-12.5* RBC-3.80* Hgb-9.5* Hct-29.1* +MCV-77* MCH-24.9* MCHC-32.4 RDW-17.7* Plt Ct-367 +[**2195-11-21**] 11:25AM BLOOD Glucose-135* UreaN-15 Creat-0.7 Na-144 +K-3.1* Cl-107 HCO3-24 AnGap-16 +[**2195-11-22**] 03:56AM BLOOD Glucose-172* UreaN-13 Creat-0.7 Na-137 +K-5.4* Cl-106 HCO3-21* AnGap-15 +[**2195-11-25**] 03:56AM BLOOD Glucose-117* UreaN-23* Creat-0.6 Na-146* +K-3.8 Cl-110* HCO3-31 AnGap-9 +[**2195-11-22**] 10:58AM BLOOD FSH-11 LH-15 Prolact-23 +[**2195-11-22**] 10:58AM BLOOD Estradl-20 +[**2195-11-22**] 10:58AM BLOOD C4-38 +[**2195-11-21**] 06:23PM BLOOD Type-ART pO2-191* pCO2-44 pH-7.38 +calTCO2-27 Base XS-0 +[**2195-11-22**] 01:39AM BLOOD Type-ART pO2-94 pCO2-44 pH-7.40 +calTCO2-28 Base XS-1 +[**2195-11-23**] 06:58PM BLOOD C1 ESTERASE INHIBITOR, FUNCTIONAL +ASSAY-PND +[**2195-11-22**] 10:50AM BLOOD ANTI-FCER1 ANTIBODY-PND + +Brief Hospital Course: +A/P: 24 y.o. female with history of idiopathic urticaria and +angioedema who presents with tongue swelling, unresponsive to H2 +blocker, steroids, epinephrine and benadryl, electively +intubated to protect airway and admitted to the MICU for further +management. +. +Respiratory: Elective intubation to protect airway in the +setting of angioedema. No underlying lung disease besides asthma +and currently not wheezy. Would expect that patient can be +easily extubated once tongue obstruction has been resolved. +Extubated on [**11-24**] after 2 days with cuff leak. +. +Angioedema: Etiology is unclear. [**Name2 (NI) **] does not have a +significant amount of atopy in personal history and has been +worked up, at least partially for C1 esterase deficiency with +C4. Patient initially treated with Solumedrol and then converted +to prednisone. Also treated with ranitidine and fexofenadine as +well as benadryl. Following extubation, benadryl discontinued. +Steroid taper started. Patient discharged on a 10 day steroid +taper and will follow up with allergy as an outpatient. She was +also continued on her ranitidine and fexofenatine transitioned +to loratadine as an outpatient. +. +Asthma: No active issues. She was continued on albuterol prn. +. +Anemia: Patient has iron deficiency anemia by labs done in +[**Month (only) **]. She had a mild hematocrit drop during +hospitalization but had no evidence of bleeding. She can be +followed up with her PCP as an outpatient. +. +Depression: On Doxepin as an outpatient. Home dose restarted +prior to discharge. +. +FEN: Following extubation tolerated regular diet without issue. +. +PPx: continued on heparin sc and H2 blocker +. +Code: FULL +. +Communication: must communicate both w father and mother. they +do not see patient at same time. +** Father, Rev. [**Known lastname 44268**] - ([**Telephone/Fax (1) 44269**] (c), ([**Telephone/Fax (1) 44270**] +(h), ([**Telephone/Fax (1) 44271**] (cell phone of Rev. [**Known lastname 44272**] son, [**Doctor First Name 71**] +** Mom [**Telephone/Fax (1) 44273**] + +Medications on Admission: +Doxepin 75 mg QHS +Loratidine 10 mg QD +Ranitidine 300 mg QD +Epi-Pen 0.3 mg/0.3 mL Syringe PRN +Ativan 0.5mg QHS + +Discharge Medications: +1. Doxepin 75 mg Capsule Sig: One (1) Capsule PO at bedtime. +2. Loratadine 10 mg Tablet Sig: One (1) Tablet PO once a day. +3. Ranitidine HCl 150 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +4. EpiPen 0.3 mg/0.3 mL Syringe Sig: One (1) injection +Intramuscular prn as needed for anaphylaxis. +Disp:*4 syringes* Refills:*0* +5. Prednisone 10 mg Tablet Sig: as directed Tablet PO as +directed for 4 days: Take 5 tablets [**11-27**], take 4 tablets [**11-28**], +take 3 tablets [**11-29**], take 2 tablets [**11-30**], then switch to 5 mg +tablets as directed. +Disp:*14 Tablet(s)* Refills:*0* +6. Prednisone 5 mg Tablet Sig: as directed Tablet PO as directed +for 3 days: Take 3 tablets on [**12-1**], then take 2 tablets on [**12-2**], +then take 1.5 tablets on [**12-3**], then discontinue. +Disp:*7 Tablet(s)* Refills:*0* +7. Albuterol 90 mcg/Actuation Aerosol Sig: 1-2 Puffs Inhalation +Q6H (every 6 hours) as needed. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +1. idiopathic angioedema + +Secondary: +1. asthma +2. chronic urticaria + + +Discharge Condition: +Ambulatory. Stable vital signs at baseline. No respiratory +distress. + + +Discharge Instructions: +Please continue to take all medications as prescribed. It is +important that you not miss any of your medications to prevent +further episodes of angioedema. Please complete your steroid +taper as outlined below. + +Please follow up with Dr. [**Last Name (STitle) **] and Dr. [**Last Name (STitle) **] as below. + +Please call your doctor or return to the hospital if you +experience any recurrent lip swelling, tongue swelling, other +facial swelling, fevers, chills, or any other concerns. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **] at [**Location (un) 8170**] on [**2195-12-24**] +at 4pm. Phone: [**Telephone/Fax (1) 44274**] + +Please follow up with Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] on [**2195-12-7**] at 7 pm. +Phone: [**Telephone/Fax (1) 1247**] + +Please follow up with Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] at [**Hospital **] on [**2195-3-24**] at 4pm. Phone: [**Telephone/Fax (1) 1247**] + + + +",63,2195-11-21 11:00:00,2195-11-26 16:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ALLERGIC REACTION," +a/p: 24 y.o. female with history of idiopathic urticaria and +angioedema who presents with tongue swelling, unresponsive to h2 +blocker, steroids, epinephrine and benadryl, electively +intubated to protect airway and admitted to the micu for further +management. +. +respiratory: elective intubation to protect airway in the +setting of angioedema. no underlying lung disease besides asthma +and currently not wheezy. would expect that patient can be +easily extubated once tongue obstruction has been resolved. +extubated on [**11-24**] after 2 days with cuff leak. +. +angioedema: etiology is unclear. [**name2 (ni) **] does not have a +significant amount of atopy in personal history and has been +worked up, at least partially for c1 esterase deficiency with +c4. patient initially treated with solumedrol and then converted +to prednisone. also treated with ranitidine and fexofenadine as +well as benadryl. following extubation, benadryl discontinued. +steroid taper started. patient discharged on a 10 day steroid +taper and will follow up with allergy as an outpatient. she was +also continued on her ranitidine and fexofenatine transitioned +to loratadine as an outpatient. +. +asthma: no active issues. she was continued on albuterol prn. +. +anemia: patient has iron deficiency anemia by labs done in +[**month (only) **]. she had a mild hematocrit drop during +hospitalization but had no evidence of bleeding. she can be +followed up with her pcp as an outpatient. +. +depression: on doxepin as an outpatient. home dose restarted +prior to discharge. +. +fen: following extubation tolerated regular diet without issue. +. +ppx: continued on heparin sc and h2 blocker +. +code: full +. +communication: must communicate both w father and mother. they +do not see patient at same time. +** father, rev. [**known lastname 44268**] - ([**telephone/fax (1) 44269**] (c), ([**telephone/fax (1) 44270**] +(h), ([**telephone/fax (1) 44271**] (cell phone of rev. [**known lastname 44272**] son, [**doctor first name 71**] +** mom [**telephone/fax (1) 44273**] + + ","PRIMARY: [Angioneurotic edema, not elsewhere classified] +SECONDARY: [Acute respiratory failure; Asthma, unspecified type, unspecified; Iron deficiency anemia, unspecified; Hypopotassemia; Essential thrombocythemia; Unspecified accident]" +28043,127710.0,14227,2176-08-07,14223,149969.0,2176-06-12,Discharge summary,"Admission Date: [**2176-6-3**] Discharge Date: [**2176-6-12**] + + +Service: MEDICINE + +Allergies: +Amoxicillin / Penicillins / Coumadin / Oxycodone / Megestrol +Acetate / Remeron / Ritalin + +Attending:[**First Name3 (LF) 5129**] +Chief Complaint: +87 yo man with history of prostate cancer s/p XRT, dementia, +prior bladder rupture, who was treated in the [**Hospital1 18**] MICU for a +new bladder rupture and urosepsis, transfered to SIRS 2 +primarily for management of resolving urosepsis, peritonitis, +post-surgical pain, and delirium. + +Major Surgical or Invasive Procedure: +Anterior bladder perforation closure, placement of suprapubic +catheter and peritoneal drain + +History of Present Illness: +87 yo man with history of prostate CA in [**2156**] s/p XRT, prior +bladder rupture, indwelling foley, multiple UTIs, and recently +dx dementia who presented to ED from NH with weeks of lower +abdominal pain and groin pain. Bright red hematuria was seen at +his nursing home. His foley was changed 1 week prior to +admission with sm amount of blood that cleared at the time. He +was unable to give other ROS. His family reported that the pt +had been having abd pain and hematuria all week since foley +change, and he was brought to the ED because he was having +fevers, nausea/vomiting and worsening pain. Prior to this past +week, he had been at his best recent baseline (w/a h/o one year +of new onset dementia), totally recovered from prior stroke, +working with PT, alert and oriented although. After he +presentated to ED he had n/v and one episode of abd pain. He +triggered for tachycardia with HR 130s while vomiting. His +abdomen was soft on exam. He had gross hematuria noted and +urology was consulted. In line with their recs a CT with IV +contrast was ordered which showed the foley catheter balloon +dilated in urethra, urology came and replaced the foley. The pt +started to become hypotensive, with a lowest BP to 65/30, and he +received approximately 2-3L liters IVF with minimal response. +He had a RIJ line placed, and he was started on norepinephrine. +His labs were notable for lactate 2.4, WBC 7.7 with 15% bands. +His UA was positive with gram negative rods. He was thus +started on cefepime/gent/vanc. + +The pt then had CT cystogram after foley replacement prior to +transfer to [**Hospital Unit Name 153**], notable for bladder rupture, this was believed +to have occured sometime in the past week either immediately or +some time after foley replacement. Urology saw the patient +again, at which point his abdomen was noted to be diffusely +tender but not hard. His BP was noted to be 100-120s while he +was being weaned off norepinephrine. After the pt was +appropriately stabilized, he was taken on [**2176-6-4**] to the OR for +repair of his bladder rupture and placement of a suprapubic +catheter. Post-op the pt was hemodynamically stable and c/o +abdominal pain. As the pt recovered from his sepsis w/ IV abx +and IV NS his serial CXRs showed worsening pulmonary edema, +which improved with diuresis with IV lasix. His SBP values also +went up to the 200s, at which point his home HTN regimen was +restarted. He also became delirious soon after surgery, likely +due to resolving urosepsis, pain, and pain medications. He was +transfered to the medical team for management of his resolving +urosepsis, post-op pain management, and delirium. + +Past Medical History: +- DM II, on insulin +- Prostate CA s/p XRT. Diagnosed in [**2156**]. +- Chronic urinary incontinence, s/p TURP [**10-6**]. +- History of UTI's, including prior MRSA and pseudomonas growth. +(Has chronic indwelling foley, changed Q6 weeks, on ppx with +cephalexin per Dr. [**Last Name (STitle) 770**] +- S/p bladder rupture and repair [**2-8**] +- A Fib, not anticoagulated due to bleeding history. +- Hyperthyroidism. +- Depression. +- Hypertension. +- PVD. +- H/o CVA [**2172**] +- Severe chronic axonal neuropathy, radiculopathy and plexopathy + +(due to XRT) per Dr. [**Last Name (STitle) **], with right foot drop for many +years. Bed ridden. +- L3 compression fracture. +- Cataract s/p bilateral laser surgery, also with ""macular +edema"" s/p dexamethasone injxn. +- Hard of hearing +- L thyroid nodule, benign. + +Social History: +[**Location (un) 1036**] resident. Smoked 2ppd tobacco x 24 years. Quit in +[**2137**]. Denies EtOH. Former WWII vet. Former Fire Fighter. Wife +is HCP. Daughter is RN, Son is engineer. + +Family History: +No illnesses, strokes, DM or early heart attacks run in the +family. + +Physical Exam: +Vitals: T:96.5 BP:132/68 P:103 (AF) R: 30 SaO2: 94% RA CVP 8 +General: Awake, responds to command, marked speech latency, +minimal response to questions. Appears frail, uncomfortable and +fatigued. +HEENT: Pale sclera. MM dry. +Neck: Supple, no LAD. R CVL IJ in place. +Pulmonary: Lungs CTA bilaterally, no wheezes, ronchi or rales +Cardiac: Tachycardic, irregular, 2/6 systolic murmur +Abdomen: BS present. Abd soft. Diffusely tender w/tap +tenderness throughout but w/o rebound or guarding. +Extremities: Mild dependent edema in UEs and [**Name Prefix (Prefixes) **] [**Last Name (Prefixes) 6816**], +cool toes with evidence of PVD/dry gangrene of right 2nd/3rd +toes. Upper extremitites well perfused. Foley in place, +draining clear urine. +Skin: No ulcers noted. Scattered excoriated lesions on right +lower quadrant/groin area. +Neurologic:Awake, responds to commands, can give coherent +answers. Oriented to person and hospital, not to specific +hospital, or year, marked speech latency. EOMI. Slight right +facial droop and UE contracture, resolves with effort. Moving +all extremities, grip strength equal. + +Pertinent Results: +Labs +Admission labs +[**2176-6-3**] 03:46PM BLOOD WBC-7.4 RBC-3.92* Hgb-11.6*# Hct-34.9*# +MCV-89 MCH-29.5 MCHC-33.1 RDW-16.1* Plt Ct-302 + +[**2176-6-3**] 03:46PM BLOOD PT-13.7* PTT-25.1 INR(PT)-1.2* + +[**2176-6-3**] 03:46PM BLOOD Glucose-124* UreaN-28* Creat-0.9 Na-139 +K-4.9 Cl-107 HCO3-21* AnGap-16 + +[**2176-6-3**] 03:46PM BLOOD Albumin-3.3* + +[**2176-6-4**] 01:31AM BLOOD Calcium-7.7* Phos-3.2 Mg-1.5* +[**2176-6-4**] 05:39AM BLOOD Type-ART pO2-70* pCO2-30* pH-7.37 +calTCO2-18* Base XS--6 +[**2176-6-3**] 03:47PM BLOOD Glucose-120* Lactate-2.4* Na-141 K-4.6 +Cl-105 calHCO3-22 + +Discharge labs: +[**2176-6-12**] 06:04AM BLOOD WBC-11.2* RBC-3.34* Hgb-10.2* Hct-30.6* +MCV-92 MCH-30.5 MCHC-33.2 RDW-16.2* Plt Ct-331 +[**2176-6-12**] 06:04AM BLOOD Glucose-133* UreaN-26* Creat-1.2 Na-139 +K-4.2 Cl-108 HCO3-24 AnGap-11 +[**2176-6-12**] 06:04AM BLOOD Calcium-7.3* Phos-2.3* Mg-2.2 +[**2176-6-12**] 06:04AM BLOOD Genta-5.8 + +Microbiology: +[**2176-6-6**] 10:25 am URINE. URINE CULTURE (Final [**2176-6-7**]): NO +GROWTH. + +[**2176-6-4**] 12:00 pm PERITONEAL FLUID + + **FINAL REPORT [**2176-6-11**]** + + GRAM STAIN (Final [**2176-6-4**]): + 4+ (>10 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + 1+ (<1 per 1000X FIELD): GRAM NEGATIVE ROD(S). + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count.. + REPORTED BY PHONE TO [**Last Name (LF) **], [**First Name3 (LF) **] @ 1822 ON [**2176-6-4**]. + + FLUID CULTURE (Final [**2176-6-11**]): + Due to mixed bacterial types (>=3) an abbreviated workup +is + performed; P.aeruginosa, S.aureus and beta strep. are +reported if + present. Susceptibility will be performed on P.aeruginosa +and + S.aureus if sparse growth or greater.. + PSEUDOMONAS AERUGINOSA. RARE GROWTH. + DR. [**First Name (STitle) **] #[**Numeric Identifier 42293**] REQUESTED SENSITIVITIES [**2176-6-9**]. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + PSEUDOMONAS AERUGINOSA + | +CEFEPIME-------------- 2 S +CEFTAZIDIME----------- 4 S +CIPROFLOXACIN--------- =>4 R +GENTAMICIN------------ <=1 S +MEROPENEM------------- 0.5 S +PIPERACILLIN---------- 8 S +PIPERACILLIN/TAZO----- 8 S +TOBRAMYCIN------------ <=1 S + + ANAEROBIC CULTURE (Final [**2176-6-8**]): NO ANAEROBES ISOLATED. + +[**2176-6-3**] 3:46 pm BLOOD CULTURE +FINAL REPORT [**2176-6-9**]** Blood Culture, Routine (Final +[**2176-6-9**]):NO GROWTH. + +[**2176-6-3**] 3:46 pm URINE from CATHETER FINAL REPORT [**2176-6-5**]** +URINE CULTURE (Final [**2176-6-5**]): + Culture workup discontinued. Further incubation showed +contamination + with mixed fecal flora. Clinical significance of +isolate(s) + uncertain. Interpret with caution. + GRAM NEGATIVE ROD(S). >100,000 ORGANISMS/ML.. + +. + +Imaging Studies: + +CT abdomen/pelvis w/ contrast ([**6-3**]) +1. Pyelonephritis of the left kidney. No abscess. +2. The Foley catheter balloon is inflated in the penile urethra. +Small amount of gas within the bladder and the left distal +ureter are most likely related to the catheterization. +3. Small amount of free fluid is noted within the pelvis. + +CT abdomen/pelvis w/ contrast ([**6-9**]) +IMPRESSIONS: +1. Small, 3.6 x 1.2 x 4 cm fluid collection at the +posterior-superior aspect +of the bladder dome, with an enhancing rim, concerning for +abscess. The right +pelvic catheter does not terminate within this collection. +2. Trace residual free fluid in the mesentery of the pelvis. +Interval +resolution of free contrast material in the pelvis. + +CXR ([**6-7**]) +The NG tube tip is in the stomach. The right internal jugular +line tip is at mid SVC. There is interval improvement up to +almost complete resolution of pulmonary edema. The left +retrocardiac opacity is still present, most likely consistent +with left lower lobe atelectasis. Pleural effusion, bilateral, +is small, left more than right. + + +Brief Hospital Course: +87 yo man with history of prostate cancer s/p XRT, prior bladder +rupture, and dementia who was treated in the [**Hospital1 18**] MICU for a +second bladder rupture, bladder rupture repair and suprapubic +catheter placement, UTI, sepsis, and peritonitis who was +transfered to the Medicine service for management of his +post-surgical pain, resolving peritonitis, delirium, and heart +rate control. +. +# Bladder rupture, urosepsis, peritonitis +. +The pt had a history of bladder rupture s/p repair in [**1-/2175**] and +presented to this admission with evidence of new rupture on CT +in setting of vague abdominal pain, nausea, vomiting and +evolving shock. He likely has friable bladder tissue in setting +of XRT for prostate CA and prior rupture. At admission it was +unclear how long the rupture had been present, but may have been +related temporally to recent foley catheter change one week +prior. He had a history of MRSA, proteus, klebsiella and +pseudomonas UTIs, and thus was started on broad spectrum +antibiotics (vancomycin, cefepime, and gentamicin) at admission. +. +He was bolused with IV fluids overnight in the MICU and went to +the OR on the first hospital day. In the OR, a perforation in +the anterior bladder wall was closed. A suprapubic catheter was +placed in a posterior bladder wall perforation, and a JP drain +was placed in the peritoneum. Cultures were taken from the +peritoneal fluid and urine that grew out Pseudomonas sensitive +to cefepime and gent, resistent to cipro. After the surgery, +the output from the JP drain continued to decrease. Chemical +analysis was consistent with serum, rather than urine, and on +the basis of this it was felt that the bladder perforations were +successfully sealed. + +Post-operatively, he was treated with IV morphine and +acetaminophen for pain control. He was transfused 2 units PRBCs +for hematocrit 27, with appropriate bump. +The pt did go on to c/o some post-surgical pain. He continued to +drain clear urine from both the urethral and suprapubic +catheters. He had a CT scan on [**6-9**] to assess for a fluid +collection or abscess in the pelvic cavity, which showed a small +fluid collection that requires follow up CT. Thus he was cleared +for the removal of his JP drain. His surgical incision remained +clean, dry, and intact. He had two negative urine cx. The cx +of his peritoneal fluid sample taken on [**2176-6-4**] showed no growth +except for rare Pseudomonas Aeruginosa growth that were shown on +[**2176-6-12**] to be sensitive to Cefepim and Vancomycin. He was +continued on his regimen of IV Cefepim, Vancomycin, and +Gentamycin for 10 days to ensure adequate tx of his UTI and +peritonitis, but was switched to solely Cefepim coverage on +[**2176-6-12**] when the culture sensitivities returns. He had a PICC +line placed on [**2176-6-12**] for the completion of his 14 day course +of Cefepime. He did have mild urine leakage around his +suprapubic catheter, but this only lasted 3 days and Urology was +not concerned given that his catheters both continued to drain +clear urine. He is scheduled for a F/U pelvic CT scan to +reasscess the region concerning for a possible abscess, and he +is also scheduled for a F/U visit with his urologist Dr. [**Last Name (STitle) 770**] +for in 2 weeks. +. +# Delirium +W/R/T the pt's mental status, after his surgery, he became +increasingly agitated and disoriented. The delirium was felt to +be secondary to pain, recent surgery, infection, and narcotics +in the setting of baseline dementia. The pt. had been receiving +IV Dilaudid for pain. Overall the narcotics were used sparingly +and his infection was treated with [**Last Name (STitle) 17577**] broad spectrum abx. +Zyprexa was used in small doses for acute agitation with +adequate sedation. He was placed in soft restraints to protect +against the pt pulling out his NGT or either of his catheters or +drains. [**2176-6-7**] was the last time that the pt received Zyprexa +for agitation/delirium, and he became alert and oriented to +person, hospital name, and month/year since [**6-9**] and has been at +his baseline since then (he has some known dementia). He is +alert and oriented x3 on D/C. + +. +# Anemia + +W/R/T the pt's anemia as above, he received 2 units PRBCs +post-operatively for hematocrit of 27. His blood count then +stabilized and he did not require further transfusions. His +hemolytic work-up was negative. He stabilized in the low 30s +throughout his stay and has been stable. +. +# Atrial fibrillation + +The pt has a h/o atrial fibrillation controlled only by +Metoprolol and has not been anticoagulated due to his h/o +hemorrhage on coumadin. While in the hospital he had multiple +episodes of atrial fibrillation with RVR to 130-160s, typically +related to pain and stress. His metoprolol had been held due to +hypotension at admission, but was restarted to manage his RVR +when his blood pressure tolerated. He continued to have such +episodes of afib with RVR throughout his stay, and thus his +Metoprolol dose was increased to 50 mg Q 8H up from 25 mg [**Hospital1 **], +which his BP tolerated. With this increase in the metoprolol +maintained an average HR in the 70s and stopped having episodes +of RVR. He will need outpt F/U to assess any need to adjust this +regimen. + +. +# Diabetes mellitus II: + +The pt was placed on a humalog sliding scale with 15U NPH in the +AM, however was taken off of the NPH due to hypoglycemia in the +MICU. on the floor, the pt developed hyperglycemia to the 200's +and was consistently over 180, at which point 4 [**Location **] +was added and his sliding scale was increased to maintain better +glycemic control. He subsequently had lower blood glucose +levels overall, but still has some levels in the 200s and now +that he is not infected and will be having decreasing levels of +pain and stress, his insulin regimen will likely need to be +adjusted at the rehab facility with [**Location 17577**] finger sticks and +his primary care should f/u on this as well. +. +# Volume status/Blood pressure + +The pt has a h/o hypertension controlled on amlodipine and +metoprolol, but he was hypotensive at admission, at whcih point +he was hydrated aggressively with IV normal saline overnight and +post-operatively. As he recovered from hypotension and sepsis, +his blood pressure came up. Serial CXRs showed worsening +pulmonary edema and he was diuresed with boluses of IV Lasix, +which completely cleared his pulmonary edema. His outpatient +antihypertensives (except for Lisinopril) were restarted as +tolerated after he had recovered from peritonitis and urosepsis. + Lisinopril should be restarted as an outpatient as tolerated by +his blood pressure with the new adjustment to the metoprolol +levels. +. +# Nutrition: +W/R/T the pt's nutrition, given the pt's delirium, an NGT was +placed for tube feeds which were given continuously. He had a +speech and swallow consult with a swallow study and was noted to +be silently aspirating and was thus deemed unable to take POs +until he has rehab and a further evaluation. NGtube and PEG +were both considered, and it was decided to plan for discharge +with the NG tube with plans for speech and [**Hospital 42294**] with a goal of reachieving ability to take POs. +For now he has a feed rate of 40ml/hr but his goal is 60ml/hr. +The rate was slowed given recent NGT residuals, but he is on +Metoclopramide and and has recently begun a bowel regimen to +ensure that there is no backup causing these residuals. +Instrucitons are to hold for residuals over 150ml. +. +# Scrotal Edema and candidal infection +The pt also experienced extreme scrotal edema for being given +about 14 liters of IV fluid for his urospesis/hypotension. His +scrotum was elevated to decrease the edema, and has decreased +but is still an issue. He also developed a erythematous rash +around his scrotum and groin area which was treated with 2% +Miconazole powder. There is no warmth in this area or any +appearance of cellulitis. The plan is to continue to manage +with miconazole powder. +. +# Depression: +The pt has a h/o depression and had been on 10mg Lexapro per +night prior to admission. His home dose of Lexapro was held +during this admission given his delirium with the plan to +restart it as an outpatient. +. +The pt was known to be a full code status. +. +Signed: +[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 42295**] (Sub-Intern) pager number [**Serial Number 11736**] +[**Last Name (LF) **], [**First Name3 (LF) 1439**] (Resident) [**Numeric Identifier 16045**] +[**Last Name (LF) **], [**First Name3 (LF) 518**] (Attending) + + +Medications on Admission: +Cephalexin daily UTI ppx +NPH 15 units QAM +RISS +Heparin SC TID +Azo cranberry 450mg daily +Bisoprolol 5mg daily +Norvasc 5mg daily +Aspirin 81mg daily +Florastor 250mg [**Hospital1 **] +Tylenol 500mg TID +MVI [**Hospital1 **] +Lisinopril 5mg daily +Simvastatin 10mg QHS +Prilosec 20mg daily +Lexapro 20mg daily +MOM PRN constipation +Bisacodyl PRN constipation +Fleet's enema PRN constipation + +Discharge Medications: +1. Amlodipine 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Acetaminophen 500 mg Tablet Sig: Two (2) Tablet PO Q 8H +(Every 8 Hours) as needed for Pain/fever for 3 weeks. +3. Miconazole Nitrate 2 % Powder Sig: One (1) Appl Topical [**Hospital1 **] +(2 times a day). +Disp:*1 Appl* Refills:*2* +4. Oxybutynin Chloride 5 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) as needed for bladder pain. +Disp:*1 Tablet(s)* Refills:*0* +5. Ondansetron 4 mg IV Q8H:PRN nausea, vomiting +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) as +needed for constipation. +Disp:*1 Tablet(s)* Refills:*0* +7. Metoprolol Tartrate 50 mg Tablet Sig: One (1) Tablet PO Q 8H +(Every 8 Hours). +Disp:*1 Tablet(s)* Refills:*2* +8. Docusate Sodium 50 mg/5 mL Liquid Sig: One (1) PO DAILY +(Daily). +Disp:*1 50 mg/5 ml* Refills:*2* +9. Insulin Glargine 100 unit/mL Solution Sig: Four (4) UNits +Subcutaneous at bedtime. +10. Cefepime 2 gram Recon Soln Sig: Two (2) g Intravenous twice +a day for 5 days. +11. Heparin (Porcine) 5,000 unit/mL Solution Sig: 5000 (5000) +Units Injection TID (3 times a day). +12. Metoclopramide 5 mg Tablet Sig: One (1) Tablet PO every six +(6) hours. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +Your primary Diagnoses Include: +Bladder rupture +Peritonitis +Urinary tract infection +sepsis + +Secondary Diagnoses +Delirium +Diabetes mellitus +Atrial fibrillation with episodes of rapid ventricular rate + + +Discharge Condition: +Stable. Afebrile. At his baseline mental status. Pain adequately +controlled on standing Tylenol. + + +Discharge Instructions: +You were admitted to the hospital for treatment of bladder +rupture and infection. You underwent surgery to repair the leak +in the bladder. Afterwards, you were treated with intravenous +antibiotics for infection in the space around the bladder. + +There have been changes to your medications as follows: + +1. Metoprolol increased to 50 mg Q 8H. This level may need to be +decreased in the future as recommended at followup with your +primary care doctor given you heart rate in the future. + +Scheduled appointments: +Please return to the [**Hospital1 18**] [**Hospital Ward Name 23**] Clinical center on [**2176-6-17**] +for your scheduled follow-up CT scan of the pelvis. +Plan for returning to the [**Hospital1 18**] for a followup appointment with +your Urologist, Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 770**] on Monday [**2176-6-17**] at 3 +PM. +The location of this appointment will be at the [**Hospital1 18**] [**Hospital Ward Name 5074**] [**Hospital Ward Name 23**] Building [**Location (un) **] Surgical Specialities. Please +call the phone number: ([**Telephone/Fax (1) 7707**] with quesitons about this +appointment. + +Please call your doctor or return to the emergency room for +fever > 101 deg F, worsening abdominal or bladder pain, or other +new symptoms concerning to you. + +Followup Instructions: +Newly-scheduled follow-ups: +- F/U CT 1 week after discharge to re-assess for abscess. CT +scheduled for [**2176-6-17**] at 8:15 AM at [**Location (un) **], [**Hospital Ward Name 5074**] [**Location (un) 470**]. +- F/U urology appointment: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 4653**], MD +Phone:[**Telephone/Fax (1) 5727**] Date/Time: [**2176-6-17**] 3:00PM. + + + +",56,2176-06-03 20:13:00,2176-06-12 17:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,SEPSIS," +87 yo man with history of prostate cancer s/p xrt, prior bladder +rupture, and dementia who was treated in the [**hospital1 18**] micu for a +second bladder rupture, bladder rupture repair and suprapubic +catheter placement, uti, sepsis, and peritonitis who was +transfered to the medicine service for management of his +post-surgical pain, resolving peritonitis, delirium, and heart +rate control. +. +# bladder rupture, urosepsis, peritonitis +. +the pt had a history of bladder rupture s/p repair in [**1-/2175**] and +presented to this admission with evidence of new rupture on ct +in setting of vague abdominal pain, nausea, vomiting and +evolving shock. he likely has friable bladder tissue in setting +of xrt for prostate ca and prior rupture. at admission it was +unclear how long the rupture had been present, but may have been +related temporally to recent foley catheter change one week +prior. he had a history of mrsa, proteus, klebsiella and +pseudomonas utis, and thus was started on broad spectrum +antibiotics (vancomycin, cefepime, and gentamicin) at admission. +. +he was bolused with iv fluids overnight in the micu and went to +the or on the first hospital day. in the or, a perforation in +the anterior bladder wall was closed. a suprapubic catheter was +placed in a posterior bladder wall perforation, and a jp drain +was placed in the peritoneum. cultures were taken from the +peritoneal fluid and urine that grew out pseudomonas sensitive +to cefepime and gent, resistent to cipro. after the surgery, +the output from the jp drain continued to decrease. chemical +analysis was consistent with serum, rather than urine, and on +the basis of this it was felt that the bladder perforations were +successfully sealed. + +post-operatively, he was treated with iv morphine and +acetaminophen for pain control. he was transfused 2 units prbcs +for hematocrit 27, with appropriate bump. +the pt did go on to c/o some post-surgical pain. he continued to +drain clear urine from both the urethral and suprapubic +catheters. he had a ct scan on [**6-9**] to assess for a fluid +collection or abscess in the pelvic cavity, which showed a small +fluid collection that requires follow up ct. thus he was cleared +for the removal of his jp drain. his surgical incision remained +clean, dry, and intact. he had two negative urine cx. the cx +of his peritoneal fluid sample taken on [**2176-6-4**] showed no growth +except for rare pseudomonas aeruginosa growth that were shown on +[**2176-6-12**] to be sensitive to cefepim and vancomycin. he was +continued on his regimen of iv cefepim, vancomycin, and +gentamycin for 10 days to ensure adequate tx of his uti and +peritonitis, but was switched to solely cefepim coverage on +[**2176-6-12**] when the culture sensitivities returns. he had a picc +line placed on [**2176-6-12**] for the completion of his 14 day course +of cefepime. he did have mild urine leakage around his +suprapubic catheter, but this only lasted 3 days and urology was +not concerned given that his catheters both continued to drain +clear urine. he is scheduled for a f/u pelvic ct scan to +reasscess the region concerning for a possible abscess, and he +is also scheduled for a f/u visit with his urologist dr. [**last name (stitle) 770**] +for in 2 weeks. +. +# delirium +w/r/t the pts mental status, after his surgery, he became +increasingly agitated and disoriented. the delirium was felt to +be secondary to pain, recent surgery, infection, and narcotics +in the setting of baseline dementia. the pt. had been receiving +iv dilaudid for pain. overall the narcotics were used sparingly +and his infection was treated with [**last name (stitle) 17577**] broad spectrum abx. +zyprexa was used in small doses for acute agitation with +adequate sedation. he was placed in soft restraints to protect +against the pt pulling out his ngt or either of his catheters or +drains. [**2176-6-7**] was the last time that the pt received zyprexa +for agitation/delirium, and he became alert and oriented to +person, hospital name, and month/year since [**6-9**] and has been at +his baseline since then (he has some known dementia). he is +alert and oriented x3 on d/c. + +. +# anemia + +w/r/t the pts anemia as above, he received 2 units prbcs +post-operatively for hematocrit of 27. his blood count then +stabilized and he did not require further transfusions. his +hemolytic work-up was negative. he stabilized in the low 30s +throughout his stay and has been stable. +. +# atrial fibrillation + +the pt has a h/o atrial fibrillation controlled only by +metoprolol and has not been anticoagulated due to his h/o +hemorrhage on coumadin. while in the hospital he had multiple +episodes of atrial fibrillation with rvr to 130-160s, typically +related to pain and stress. his metoprolol had been held due to +hypotension at admission, but was restarted to manage his rvr +when his blood pressure tolerated. he continued to have such +episodes of afib with rvr throughout his stay, and thus his +metoprolol dose was increased to 50 mg q 8h up from 25 mg [**hospital1 **], +which his bp tolerated. with this increase in the metoprolol +maintained an average hr in the 70s and stopped having episodes +of rvr. he will need outpt f/u to assess any need to adjust this +regimen. + +. +# diabetes mellitus ii: + +the pt was placed on a humalog sliding scale with 15u nph in the +am, however was taken off of the nph due to hypoglycemia in the +micu. on the floor, the pt developed hyperglycemia to the 200s +and was consistently over 180, at which point 4 [**location **] +was added and his sliding scale was increased to maintain better +glycemic control. he subsequently had lower blood glucose +levels overall, but still has some levels in the 200s and now +that he is not infected and will be having decreasing levels of +pain and stress, his insulin regimen will likely need to be +adjusted at the rehab facility with [**location 17577**] finger sticks and +his primary care should f/u on this as well. +. +# volume status/blood pressure + +the pt has a h/o hypertension controlled on amlodipine and +metoprolol, but he was hypotensive at admission, at whcih point +he was hydrated aggressively with iv normal saline overnight and +post-operatively. as he recovered from hypotension and sepsis, +his blood pressure came up. serial cxrs showed worsening +pulmonary edema and he was diuresed with boluses of iv lasix, +which completely cleared his pulmonary edema. his outpatient +antihypertensives (except for lisinopril) were restarted as +tolerated after he had recovered from peritonitis and urosepsis. + lisinopril should be restarted as an outpatient as tolerated by +his blood pressure with the new adjustment to the metoprolol +levels. +. +# nutrition: +w/r/t the pts nutrition, given the pts delirium, an ngt was +placed for tube feeds which were given continuously. he had a +speech and swallow consult with a swallow study and was noted to +be silently aspirating and was thus deemed unable to take pos +until he has rehab and a further evaluation. ngtube and peg +were both considered, and it was decided to plan for discharge +with the ng tube with plans for speech and [**hospital 42294**] with a goal of reachieving ability to take pos. +for now he has a feed rate of 40ml/hr but his goal is 60ml/hr. +the rate was slowed given recent ngt residuals, but he is on +metoclopramide and and has recently begun a bowel regimen to +ensure that there is no backup causing these residuals. +instrucitons are to hold for residuals over 150ml. +. +# scrotal edema and candidal infection +the pt also experienced extreme scrotal edema for being given +about 14 liters of iv fluid for his urospesis/hypotension. his +scrotum was elevated to decrease the edema, and has decreased +but is still an issue. he also developed a erythematous rash +around his scrotum and groin area which was treated with 2% +miconazole powder. there is no warmth in this area or any +appearance of cellulitis. the plan is to continue to manage +with miconazole powder. +. +# depression: +the pt has a h/o depression and had been on 10mg lexapro per +night prior to admission. his home dose of lexapro was held +during this admission given his delirium with the plan to +restart it as an outpatient. +. +the pt was known to be a full code status. +. +signed: +[**first name8 (namepattern2) **] [**last name (namepattern1) 42295**] (sub-intern) pager number [**serial number 11736**] +[**last name (lf) **], [**first name3 (lf) 1439**] (resident) [**numeric identifier 16045**] +[**last name (lf) **], [**first name3 (lf) 518**] (attending) + + + ","PRIMARY: [Septicemia due to pseudomonas] +SECONDARY: [Septic shock; Accidental puncture or laceration during a procedure, not elsewhere classified; Other suppurative peritonitis; Urinary tract infection, site not specified; Pulmonary congestion and hypostasis; Acute posthemorrhagic anemia; Rupture of bladder, nontraumatic; Severe sepsis; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Atrial fibrillation; Personal history of malignant neoplasm of prostate; Long-term (current) use of insulin; Gross hematuria; Unspecified essential hypertension; Depressive disorder, not elsewhere classified; Mononeuritis of lower limb, unspecified; Late effect of radiation; ; Other specified antibiotics causing adverse effects in therapeutic use; Pressure ulcer, lower back; Pressure ulcer, heel; Pressure ulcer, stage II; Pressure ulcer, stage I; Candidiasis of skin and nails; Edema of male genital organs]" +28043,127710.0,14227,2176-08-07,14224,135417.0,2176-07-04,Discharge summary,"Admission Date: [**2176-6-17**] Discharge Date: [**2176-7-4**] + + +Service: MEDICINE + +Allergies: +Amoxicillin / Penicillins / Coumadin / Oxycodone / Megestrol +Acetate / Remeron / Ritalin + +Attending:[**First Name3 (LF) 689**] +Chief Complaint: +Altered mental status. + +Major Surgical or Invasive Procedure: +Endotracheal intubation. +PICC line placement. +Dobhoff (nasogastric) tube placement. +PEG tube placement + + +History of Present Illness: +Mr. [**Known lastname 42290**] is an 87 year-old man with atrial fibrillation, +diabetes mellitus II, prostate cancer s/p XRT, cerebrovascular +accident, dementia, and bladder rupture most recently on [**6-3**], +s/p repair and complicated by peritonitis, delirium who presents +from rehab with altered mental status. + +Regarding his prior hospitalization, he presented to [**Hospital1 18**] on +[**6-3**] after the onset of abdominal pain and hematuria. His foley +was replaced with no improvement in his symptoms, subsequently +undergoing CT scan with findings consistent with ruptured +bladder. He had also become hypotensive at that point requiring +pressors and transfer to the MICU. He underwent repair of an +anterior bladder rupture on [**6-4**] with placement of a foley, SP +catheter, and JP drain. Peritoneal culture grew rare +Pseudomonas, and his antibiotics were initially Vanco, Cefepime, +Gent x10 days, narrowed to Cefepime. A follow up CT scan +demonstrated a small fluid collection, though it was unclear if +it was indeed an abscess. He was discharged to rehab with a +PICC, foley, SP catheter, completion of 14-day course of +Cefepime, and follow up CT scan and urology follow-up. + +Per report, the patient was found today at [**Hospital **] rehab with +altered mental status. Per report, he was more lethargic and +confused during the course of the day. Patient is usually +verbal, though was found to be non-verbal prior to transfer, +lying supine and moaning. FSBG 187. The son visited him last +Thursday and was reportedly at his baseline, conversing, lucid, +awake and alert. However, yesterday he was less conversant, +calling his wife's name, but responding to commands. He was also +noted to be tremulous all over. There was no obvious indication +of new symptoms such as new pain, respiratory symptoms, new +numbness/weakness or other neurological symptoms. + +In the ED, vitals were 99.6, 74, 130/85, 25, 95% on RA. He was +agitated without meningismus, and was intubated for airway +protection (100% AC 550x12, 100%). Admission labs revealed a +white count of 23 and Cr of 2.3. LP done in ER, needle trauma at +end of tap. He was given vancomycin, ceftriaxone, and zosyn +(started), which was changed to cefepime given his PCN allergy. +Given 2L fluid, and was transiently hypotensive to 90s, which +responded to 130s systolic after 250cc bolus. + +Past Medical History: +-DM II, on insulin +-prostate CA s/p XRT [**2156**] +-chronic urinary incontinence, s/p TURP [**10-6**] +-history of UTIs, including prior MRSA, klebsiella, proteus, +pseuduomonas +-s/p bladder rupture and repair x2, [**2-8**], [**6-8**] +-atrial fibrillation, not anticoagulated due to h/o bleeding +-hyperthyroidism +-depression +-hypertension +-moderate aortic stenosis on TTE [**5-/2176**] +-peripheral vascular disease +-h/o CVA [**2172**] +-severe chronic axonal neuropathy, radiculopathy and plexopathy +(due to XRT) per Dr. [**Last Name (STitle) **], with right foot drop for many +years +-L3 compression fracture +-cataract s/p bilateral laser surgery, also with ""macular edema"" +s/p dexamethasone injection +-hard of hearing +-left thyroid nodule, benign + +Social History: +Smoked 2 ppd tobacco x24 years. Quit in [**2137**]. Denies EtOH. +Former WWII vet. Former Fire Fighter. Wife is HCP. Daughter is +RN, son is engineer. + +Family History: +No illnesses, strokes, DM or early heart attacks run in the +family. + +Physical Exam: +Vitals: Tm 98.4, Tc 97.8, HR 58 (58-78), BP 143/82, RR 17, sat +100%RA +General: minimally interactive; squeezes hands on command but +will not close eyes on command; winces when pressure is applied +to suprapubic region +Lungs: clear anteriorly +Chest: RRR, normal S1/S2 +Abdomen: moderate suprapubic tenderess, normal bowel sounds; +suprapubic catheter, folety catheter, and rectal tube are in +place +Extremites: hands with trace pitting edema, diffuse ecchymoses, +legs are non-edematous + +Pertinent Results: +Labs at Admission: + +[**2176-6-17**] 03:22AM BLOOD WBC-22.6*# RBC-3.76* Hgb-11.3* Hct-35.8* +MCV-95 MCH-30.0 MCHC-31.4 RDW-16.3* Plt Ct-522*# +[**2176-6-17**] 03:22AM BLOOD Neuts-88.5* Lymphs-6.3* Monos-3.4 Eos-1.4 +Baso-0.4 +[**2176-6-17**] 03:22AM BLOOD PT-15.5* PTT-29.5 INR(PT)-1.4* +[**2176-6-17**] 03:22AM BLOOD Glucose-184* UreaN-53* Creat-2.3*# Na-135 +K-4.7 Cl-102 HCO3-24 AnGap-14 +[**2176-6-18**] 04:17AM BLOOD ALT-9 AST-14 LD(LDH)-247 TotBili-0.2 +[**2176-6-17**] 03:22AM BLOOD Albumin-2.6* Calcium-8.1* Phos-2.5* +Mg-2.1 +[**2176-6-18**] 04:17AM BLOOD calTIBC-164* Hapto-184 Ferritn-251 +TRF-126* +[**2176-6-19**] 03:49AM BLOOD VitB12-1024* Folate-14.6 + +Micro Studies: + +[**2176-6-29**] URINE URINE CULTURE- negative +[**2176-6-28**] STOOL CLOSTRIDIUM DIFFICILE TOXIN A & B TEST- +negative +[**2176-6-20**] BLOOD CULTURE Blood Culture, Routine- negative +[**2176-6-19**] SPUTUM GRAM STAIN-FINAL; RESPIRATORY CULTURE- yeast +[**2176-6-19**] STOOL CLOSTRIDIUM DIFFICILE TOXIN A & B TEST- +negative +[**2176-6-19**] BLOOD CULTURE Blood Culture, Routine- negative +[**2176-6-19**] URINE URINE CULTURE- negative +[**2176-6-18**] URINE Legionella Urinary Antigen - negative +[**2176-6-17**] SPUTUM GRAM STAIN-FINAL; RESPIRATORY CULTURE-FINAL +{YEAST, STAPH AUREUS COAG +}; LEGIONELLA CULTURE- negative +GRAM STAIN (Final [**2176-6-17**]): + >25 PMNs and <10 epithelial cells/100X field. + 2+ (1-5 per 1000X FIELD): GRAM POSITIVE COCCI. + IN PAIRS AND CLUSTERS. + 1+ (<1 per 1000X FIELD): YEAST(S). +_________________________________________________________ + STAPH AUREUS COAG + + | +CLINDAMYCIN----------- =>8 R +ERYTHROMYCIN---------- =>8 R +GENTAMICIN------------ <=0.5 S +LEVOFLOXACIN---------- =>8 R +OXACILLIN------------- =>4 R +RIFAMPIN-------------- <=0.5 S +TETRACYCLINE---------- 2 S +TRIMETHOPRIM/SULFA---- <=0.5 S +VANCOMYCIN------------ <=1 S +[**2176-6-17**] CSF;SPINAL FLUID GRAM STAIN-FINAL; FLUID CULTURE- +negative +[**2176-6-17**] SPUTUM GRAM STAIN-FINAL; RESPIRATORY CULTURE- +negative +[**2176-6-17**] BLOOD CULTURE Blood Culture, Routine- negative +[**2176-6-17**] BLOOD CULTURE Blood Culture, Routine- negative +[**2176-6-17**] URINE URINE CULTURE- negative + +Cerebrospinal Fluid: + +[**2176-6-17**] 05:30AM CEREBROSPINAL FLUID (CSF) WBC-19 RBC-8450* +Polys-78 Lymphs-14 Monos-5 Eos-3 +[**2176-6-17**] 05:30AM CEREBROSPINAL FLUID (CSF) WBC-11 RBC-1650* +Polys-78 Lymphs-15 Monos-7 +[**2176-6-17**] 05:30AM CEREBROSPINAL FLUID (CSF) TotProt-59* +Glucose-101 +[**2176-6-17**] 11:19AM CEREBROSPINAL FLUID (CSF) HERPES SIMPLEX VIRUS +PCR-negative for HSV 1 and HSV 2 + +Imaging Studies: + +CT Abdomen and Pelvis ([**6-17**]): +1. Anasarca. New small left greater than right pleural +effusions. Tiny pericardial effusion. +2. Right basilar airspace opacity concerning for aspiration. +3. Superpubic and Foley catheter remain within the decompressed +bladder. [**Doctor Last Name 406**] drain is removed. The fluid in the previously +seen rim-enhancing pelvic fluid collection has essentially +resolved, with now 2.4 x 1.7 x 1.8 cm soft tissue seen remaining +where fluid collection was. No definite new fluid collection +seen. + +EEG ([**6-17**]): +IMPRESSION: This is an abnormal portable EEG recording due to +the independent left and right parasagittal discharges and the +focal slowing +in the parasagittal area. The background was slow alternating +with periods of relative suppression, as well as multifocal +slowing. For about 15 minutes, there were bifrontally +predominant triphasic waves that evolved into more rhythmic +pattern reaching a maximum of 1.5-2 Hz. The first and second +abnormalities suggest cortical irritability as well as +subcortical dysfunction in the parasagittal areas. The third +abnormality suggests multifocal a moderate to severe +encephalopathy. The fourth abnormality may be seen in +encephalopathies but also raises concern for electrographic +seizure activity, although no clear change was seen in the +patient's behavior on video. Thus, continuous EEG recording may +be of further diagnostic value in this patient to evaluate for +subclinical seizures. Of note is the irregular cardiac rhythm +suggestive of atrial fibrilllation. + +TTE ([**6-19**]): +The left atrium is normal in size. There is mild symmetric left +ventricular hypertrophy. The left ventricular cavity size is +normal. Due to suboptimal technical quality, a focal wall motion +abnormality cannot be fully excluded. Overall left ventricular +systolic function is low normal (LVEF 50-55%). There is no +ventricular septal defect. Right ventricular chamber size and +free wall motion are normal. The aortic valve leaflets are +moderately thickened. There is moderate aortic valve stenosis +(valve area 1.0-1.2cm2). Trace aortic regurgitation is seen. The +mitral valve leaflets are mildly thickened. Moderate (2+) mitral +regurgitation is seen. The pulmonary artery systolic pressure +could not be determined. There is a small pericardial effusion. +There are no echocardiographic signs of tamponade. Compared with +the prior study (images reviewed) of [**2172-12-17**], the degree of +AS is now moderate. + +MRI Head ([**6-24**]): +IMPRESSION: No evidence for acute ischemia. Slight progression +of periventricular hyperintensity which could reflect +progression of small vessel ischemia. Less likely, this could +represent transependymal CSF flow from NPH. Foci of hypersignal +in the right frontal and parietal lobe which were not present on +the prior MRI may represent interval ischemia which is chronic. +. +. +DISCHARGE LABS: +. +Na: 147 +Cl: 118 +Cr: 1.7 +Hct: 23.8 +Ca: 8.0 + +Brief Hospital Course: +In summary an 87 year-old man with history of atrial +fibrillation, diabetes mellitus II, dementia, history of +prostate cancer s/p XRT c/b bladder rupture x2 with recent +surgical repair, MDR UTIs, who presents from rehab with altered +mental status. + +# Altered mental status: etiology is not clear. He was intubated +in the emergency room for airway protection (extubated later on +[**6-24**]). He had a leukocytosis of 23 with neutrophilic +predominance at admission. CSF was traumatic but we could not +exclude bacterial meningitis. Other considerations included +delirium in setting of infection (meningitis, aspiration +pneumonia, or urinary tract infection), acute renal failure, and +seizures. He was treated empirically for meningitis with +ceftriaxone, vancomycin, and Bactrim. Neurology was consulted. +EEG showed possible non-convulsive status epilepticus while in +the intensive care unit. Therefore he was started on Dilantin. +MRI showed no evidence of acute vascular event. Despite the +above treatments, his mental status did not return to +pre-admission baseline. After transfer to the floors, he had +completed a 14-day course of antibiotics and remained +therapeutic on Dilantin. The patient's mental status has +gradually improved, and Neurology recommended continuing +Dilantin and follow up with Neurology upon discharge. + +# Seizures: MRI was without mass or evidence of stroke. +Non-convulsive status epilepticus was felt to be precipitated by +meningitis. He was loaded on phenytoin and levels were followed +until therapeutic. + +# Acute renal failure: His creatinine was up to 2.3 during this +admission from previous baseline 0.5-1.0. This was thought +secondary to gentamicin toxicity during prior admission or +possibly precipitated by infection/sepsis. His creatinine came +down with treatment of infection, but has not reached previous +baseline. He is still producing good amount of urine and +creatinine has been stable at 1.7. + +# Anemia: his baseline hematocrit from early [**2176**] is 30. There +were no signs of active bleeding on exam. The anemia was felt to +be due to phlebotomy effect and inflammation and chronic +disease. We maintained an active type and screen. Blood +transfusion was not necessary. + +# S/p Bladder repair: He has had two bladder ruptures in the +last two years. He now has a chronic foley and suprapubic +catheter. At last admission the bladder perforation appeared to +be healing well with clear drainage. During this admission there +was a small fluid collection in the peritoneum, which was a +non-specific finding. His foley and supra-pubic catheters +continued to drain clear urine, and abdominal exam was benign. + +# Diabetes mellitus II: bood sugars were stable. We continued +his home insulin sliding scale and held his Lantus initially. +We restarted this medication on [**7-2**], and his sugars remained +within good contol. + +# Atrial fibrillation: he is not on anticoagulation due to +history of bleeding. In the intensive care unit he had episodes +of atrial fibrillation with RVR. He was intially treated with +metoprolol, then was loaded on amiodorone with good rate +control. After transfer to the floors, there was concern of +high-degree atrioventricular block. Electrophysiology service +was consulted and recommended that amiodorone be discontinued. +He was kept on metoprolol at a dose of 25 mg twice daily and he +was started on ASA 81 mg daily prior to admission. + +# Hypertension: We continued metoprolol and held amlodipine. +Blood pressure control was good on this regimen. + +Medications on Admission: +Amlodipine 5 mg PO DAILY (Daily). +Acetaminophen 500 mg (2) Tablet PO Q 8H (Every 8 Hours) as +needed Miconazole Nitrate 2 % Powder (1) Appl Topical [**Hospital1 **] +Ondansetron 4 mg IV Q8H:PRN nausea, vomiting +Senna 8.6 mg (1) Tablet PO DAILY (Daily) as needed for +constipation +Metoprolol Tartrate 50 mg PO Q8H +Docusate Sodium 50 mg/5 mL Liquid (1) PO DAILY +Insulin Glargine 6 Units Subcutaneous at bedtime +Cefepime 2 gram [**Hospital1 **] through [**6-16**] +Lovenox 40mg SC Daily +Metoclopramide 5 mg PO every six 6 hours + +Discharge Medications: +1. Phenytoin 125 mg/5 mL Suspension Sig: One (1) PO TID (3 +times a day). +2. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +3. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +4. Miconazole Nitrate 2 % Powder Sig: One (1) Appl Topical [**Hospital1 **] +(2 times a day) as needed for rash. +5. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed for constipation. +6. Docusate Sodium 50 mg/5 mL Liquid Sig: Ten (10) mL PO BID (2 +times a day). +7. Insulin Glargine 100 unit/mL Cartridge Sig: Six (6) Units +Subcutaneous at bedtime. +8. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) mL +Injection TID (3 times a day). +9. Aspirin 81 mg Tablet Sig: One (1) Tablet PO once a day. +10. Sodium Chloride 0.9% Flush 10 mL IV PRN line flush +PICC, non-heparin dependent: Flush with 10 mL Normal Saline +daily and PRN per lumen. +11. Heparin Flush (10 units/ml) 2 mL IV PRN line flush +PICC, heparin dependent: Flush with 10mL Normal Saline followed +by Heparin as above daily and PRN per lumen. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +PRIMARY DIAGNOSES +Meningitis +Atrial fibrillation with rapid ventricular response +Non-convulsive status epilepticus +Acute renal failure +. +SECONDARY DIAGNOSES +History of bladder rupture +Moderate aortic stenosis +Diabetes type II + + +Discharge Condition: +Vital signs stable. Afebrile. + + +Discharge Instructions: +You were admitted to the hospital for evaluation of altered +mental status. We believe that you had an infection, although we +were not able to isolate the source. We treated you with a +fourteen-day course of antibiotics, which you completed while in +the hospital. In addition, we noticed that you were having +seizures and started you on a medicine to help prevent seizures +in the future. We also placed a G-tube in your stomach in order +to improve your nutrition. +. +While you were here, we made the following changes to your +medications: +1. We started you on Dilantin for seizures +2. We discontinued your Amlodipine and decreased your +Metoprolol to 25 mg PO twice daily +3. We discontinued your Ondansetron +4. We started you on Aspirin 81 mg daily +5. We increased your senna to twice daily instead of once daily +6. We discontinued your Lovenox injections and started you on +Heparing injections three times daily + +Please take all medications as prescribed. + +Please keep all previously scheduled appointments + +Please return to the ED or your healthcare facility if you +experience shortness of breath, chest pain, fevers, chills, +increasing confusion, seizures, or any other concerning +symptoms. + +Followup Instructions: +Please follow-up with your primary provider one week after being +discharged from [**Hospital 100**] Rehab. Their phone number is +[**Telephone/Fax (1) 3070**]. + +PROVIDER: [**Name10 (NameIs) **] [**First Name4 (NamePattern1) 429**] [**Last Name (NamePattern1) 118**] (Nephrology). Date and time: [**8-9**] at 11am. Location: [**Hospital Ward Name 23**] Clinical Center [**Location (un) 436**]. +Phone number: [**Telephone/Fax (1) 60**] + +PROVIDER: [**Name10 (NameIs) **], [**Name11 (NameIs) 1112**] MD (Neurology). Date/Time: [**2176-10-2**] at +1 PM. Location: [**Hospital Ward Name 23**] Building [**Location (un) **]. + + + +Completed by:[**2176-7-4**]",34,2176-06-17 06:36:00,2176-07-04 14:01:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,ALTERED MENTAL STATUS," +in summary an 87 year-old man with history of atrial +fibrillation, diabetes mellitus ii, dementia, history of +prostate cancer s/p xrt c/b bladder rupture x2 with recent +surgical repair, mdr utis, who presents from rehab with altered +mental status. + +# altered mental status: etiology is not clear. he was intubated +in the emergency room for airway protection (extubated later on +[**6-24**]). he had a leukocytosis of 23 with neutrophilic +predominance at admission. csf was traumatic but we could not +exclude bacterial meningitis. other considerations included +delirium in setting of infection (meningitis, aspiration +pneumonia, or urinary tract infection), acute renal failure, and +seizures. he was treated empirically for meningitis with +ceftriaxone, vancomycin, and bactrim. neurology was consulted. +eeg showed possible non-convulsive status epilepticus while in +the intensive care unit. therefore he was started on dilantin. +mri showed no evidence of acute vascular event. despite the +above treatments, his mental status did not return to +pre-admission baseline. after transfer to the floors, he had +completed a 14-day course of antibiotics and remained +therapeutic on dilantin. the patients mental status has +gradually improved, and neurology recommended continuing +dilantin and follow up with neurology upon discharge. + +# seizures: mri was without mass or evidence of stroke. +non-convulsive status epilepticus was felt to be precipitated by +meningitis. he was loaded on phenytoin and levels were followed +until therapeutic. + +# acute renal failure: his creatinine was up to 2.3 during this +admission from previous baseline 0.5-1.0. this was thought +secondary to gentamicin toxicity during prior admission or +possibly precipitated by infection/sepsis. his creatinine came +down with treatment of infection, but has not reached previous +baseline. he is still producing good amount of urine and +creatinine has been stable at 1.7. + +# anemia: his baseline hematocrit from early [**2176**] is 30. there +were no signs of active bleeding on exam. the anemia was felt to +be due to phlebotomy effect and inflammation and chronic +disease. we maintained an active type and screen. blood +transfusion was not necessary. + +# s/p bladder repair: he has had two bladder ruptures in the +last two years. he now has a chronic foley and suprapubic +catheter. at last admission the bladder perforation appeared to +be healing well with clear drainage. during this admission there +was a small fluid collection in the peritoneum, which was a +non-specific finding. his foley and supra-pubic catheters +continued to drain clear urine, and abdominal exam was benign. + +# diabetes mellitus ii: bood sugars were stable. we continued +his home insulin sliding scale and held his lantus initially. +we restarted this medication on [**7-2**], and his sugars remained +within good contol. + +# atrial fibrillation: he is not on anticoagulation due to +history of bleeding. in the intensive care unit he had episodes +of atrial fibrillation with rvr. he was intially treated with +metoprolol, then was loaded on amiodorone with good rate +control. after transfer to the floors, there was concern of +high-degree atrioventricular block. electrophysiology service +was consulted and recommended that amiodorone be discontinued. +he was kept on metoprolol at a dose of 25 mg twice daily and he +was started on asa 81 mg daily prior to admission. + +# hypertension: we continued metoprolol and held amlodipine. +blood pressure control was good on this regimen. + + ","PRIMARY: [Meningitis, unspecified] +SECONDARY: [Grand mal status; Acute kidney failure, unspecified; Acute respiratory failure; Acidosis; Other complications due to other internal prosthetic device, implant, and graft; ; Atrial fibrillation; ; Other urinary incontinence; Hypotension, unspecified; Peripheral vascular disease, unspecified; Benign essential hypertension; Anemia of other chronic disease; Hyperpotassemia; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Pressure ulcer, lower back; Pressure ulcer, unspecified stage; Brachial plexus lesions; Neuralgia, neuritis, and radiculitis, unspecified; Other acquired deformities of ankle and foot; Aortic valve disorders; Other persistent mental disorders due to conditions classified elsewhere; Other postprocedural status; Personal history of malignant neoplasm of prostate; Personal history of transient ischemic attack (TIA), and cerebral infarction without residual deficits; Personal history of Methicillin resistant Staphylococcus aureus; Long-term (current) use of insulin; Radiological procedure and radiotherapy as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure]" +28043,135417.0,14224,2176-07-04,14223,149969.0,2176-06-12,Discharge summary,"Admission Date: [**2176-6-3**] Discharge Date: [**2176-6-12**] + + +Service: MEDICINE + +Allergies: +Amoxicillin / Penicillins / Coumadin / Oxycodone / Megestrol +Acetate / Remeron / Ritalin + +Attending:[**First Name3 (LF) 5129**] +Chief Complaint: +87 yo man with history of prostate cancer s/p XRT, dementia, +prior bladder rupture, who was treated in the [**Hospital1 18**] MICU for a +new bladder rupture and urosepsis, transfered to SIRS 2 +primarily for management of resolving urosepsis, peritonitis, +post-surgical pain, and delirium. + +Major Surgical or Invasive Procedure: +Anterior bladder perforation closure, placement of suprapubic +catheter and peritoneal drain + +History of Present Illness: +87 yo man with history of prostate CA in [**2156**] s/p XRT, prior +bladder rupture, indwelling foley, multiple UTIs, and recently +dx dementia who presented to ED from NH with weeks of lower +abdominal pain and groin pain. Bright red hematuria was seen at +his nursing home. His foley was changed 1 week prior to +admission with sm amount of blood that cleared at the time. He +was unable to give other ROS. His family reported that the pt +had been having abd pain and hematuria all week since foley +change, and he was brought to the ED because he was having +fevers, nausea/vomiting and worsening pain. Prior to this past +week, he had been at his best recent baseline (w/a h/o one year +of new onset dementia), totally recovered from prior stroke, +working with PT, alert and oriented although. After he +presentated to ED he had n/v and one episode of abd pain. He +triggered for tachycardia with HR 130s while vomiting. His +abdomen was soft on exam. He had gross hematuria noted and +urology was consulted. In line with their recs a CT with IV +contrast was ordered which showed the foley catheter balloon +dilated in urethra, urology came and replaced the foley. The pt +started to become hypotensive, with a lowest BP to 65/30, and he +received approximately 2-3L liters IVF with minimal response. +He had a RIJ line placed, and he was started on norepinephrine. +His labs were notable for lactate 2.4, WBC 7.7 with 15% bands. +His UA was positive with gram negative rods. He was thus +started on cefepime/gent/vanc. + +The pt then had CT cystogram after foley replacement prior to +transfer to [**Hospital Unit Name 153**], notable for bladder rupture, this was believed +to have occured sometime in the past week either immediately or +some time after foley replacement. Urology saw the patient +again, at which point his abdomen was noted to be diffusely +tender but not hard. His BP was noted to be 100-120s while he +was being weaned off norepinephrine. After the pt was +appropriately stabilized, he was taken on [**2176-6-4**] to the OR for +repair of his bladder rupture and placement of a suprapubic +catheter. Post-op the pt was hemodynamically stable and c/o +abdominal pain. As the pt recovered from his sepsis w/ IV abx +and IV NS his serial CXRs showed worsening pulmonary edema, +which improved with diuresis with IV lasix. His SBP values also +went up to the 200s, at which point his home HTN regimen was +restarted. He also became delirious soon after surgery, likely +due to resolving urosepsis, pain, and pain medications. He was +transfered to the medical team for management of his resolving +urosepsis, post-op pain management, and delirium. + +Past Medical History: +- DM II, on insulin +- Prostate CA s/p XRT. Diagnosed in [**2156**]. +- Chronic urinary incontinence, s/p TURP [**10-6**]. +- History of UTI's, including prior MRSA and pseudomonas growth. +(Has chronic indwelling foley, changed Q6 weeks, on ppx with +cephalexin per Dr. [**Last Name (STitle) 770**] +- S/p bladder rupture and repair [**2-8**] +- A Fib, not anticoagulated due to bleeding history. +- Hyperthyroidism. +- Depression. +- Hypertension. +- PVD. +- H/o CVA [**2172**] +- Severe chronic axonal neuropathy, radiculopathy and plexopathy + +(due to XRT) per Dr. [**Last Name (STitle) **], with right foot drop for many +years. Bed ridden. +- L3 compression fracture. +- Cataract s/p bilateral laser surgery, also with ""macular +edema"" s/p dexamethasone injxn. +- Hard of hearing +- L thyroid nodule, benign. + +Social History: +[**Location (un) 1036**] resident. Smoked 2ppd tobacco x 24 years. Quit in +[**2137**]. Denies EtOH. Former WWII vet. Former Fire Fighter. Wife +is HCP. Daughter is RN, Son is engineer. + +Family History: +No illnesses, strokes, DM or early heart attacks run in the +family. + +Physical Exam: +Vitals: T:96.5 BP:132/68 P:103 (AF) R: 30 SaO2: 94% RA CVP 8 +General: Awake, responds to command, marked speech latency, +minimal response to questions. Appears frail, uncomfortable and +fatigued. +HEENT: Pale sclera. MM dry. +Neck: Supple, no LAD. R CVL IJ in place. +Pulmonary: Lungs CTA bilaterally, no wheezes, ronchi or rales +Cardiac: Tachycardic, irregular, 2/6 systolic murmur +Abdomen: BS present. Abd soft. Diffusely tender w/tap +tenderness throughout but w/o rebound or guarding. +Extremities: Mild dependent edema in UEs and [**Name Prefix (Prefixes) **] [**Last Name (Prefixes) 6816**], +cool toes with evidence of PVD/dry gangrene of right 2nd/3rd +toes. Upper extremitites well perfused. Foley in place, +draining clear urine. +Skin: No ulcers noted. Scattered excoriated lesions on right +lower quadrant/groin area. +Neurologic:Awake, responds to commands, can give coherent +answers. Oriented to person and hospital, not to specific +hospital, or year, marked speech latency. EOMI. Slight right +facial droop and UE contracture, resolves with effort. Moving +all extremities, grip strength equal. + +Pertinent Results: +Labs +Admission labs +[**2176-6-3**] 03:46PM BLOOD WBC-7.4 RBC-3.92* Hgb-11.6*# Hct-34.9*# +MCV-89 MCH-29.5 MCHC-33.1 RDW-16.1* Plt Ct-302 + +[**2176-6-3**] 03:46PM BLOOD PT-13.7* PTT-25.1 INR(PT)-1.2* + +[**2176-6-3**] 03:46PM BLOOD Glucose-124* UreaN-28* Creat-0.9 Na-139 +K-4.9 Cl-107 HCO3-21* AnGap-16 + +[**2176-6-3**] 03:46PM BLOOD Albumin-3.3* + +[**2176-6-4**] 01:31AM BLOOD Calcium-7.7* Phos-3.2 Mg-1.5* +[**2176-6-4**] 05:39AM BLOOD Type-ART pO2-70* pCO2-30* pH-7.37 +calTCO2-18* Base XS--6 +[**2176-6-3**] 03:47PM BLOOD Glucose-120* Lactate-2.4* Na-141 K-4.6 +Cl-105 calHCO3-22 + +Discharge labs: +[**2176-6-12**] 06:04AM BLOOD WBC-11.2* RBC-3.34* Hgb-10.2* Hct-30.6* +MCV-92 MCH-30.5 MCHC-33.2 RDW-16.2* Plt Ct-331 +[**2176-6-12**] 06:04AM BLOOD Glucose-133* UreaN-26* Creat-1.2 Na-139 +K-4.2 Cl-108 HCO3-24 AnGap-11 +[**2176-6-12**] 06:04AM BLOOD Calcium-7.3* Phos-2.3* Mg-2.2 +[**2176-6-12**] 06:04AM BLOOD Genta-5.8 + +Microbiology: +[**2176-6-6**] 10:25 am URINE. URINE CULTURE (Final [**2176-6-7**]): NO +GROWTH. + +[**2176-6-4**] 12:00 pm PERITONEAL FLUID + + **FINAL REPORT [**2176-6-11**]** + + GRAM STAIN (Final [**2176-6-4**]): + 4+ (>10 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + 1+ (<1 per 1000X FIELD): GRAM NEGATIVE ROD(S). + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count.. + REPORTED BY PHONE TO [**Last Name (LF) **], [**First Name3 (LF) **] @ 1822 ON [**2176-6-4**]. + + FLUID CULTURE (Final [**2176-6-11**]): + Due to mixed bacterial types (>=3) an abbreviated workup +is + performed; P.aeruginosa, S.aureus and beta strep. are +reported if + present. Susceptibility will be performed on P.aeruginosa +and + S.aureus if sparse growth or greater.. + PSEUDOMONAS AERUGINOSA. RARE GROWTH. + DR. [**First Name (STitle) **] #[**Numeric Identifier 42293**] REQUESTED SENSITIVITIES [**2176-6-9**]. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + PSEUDOMONAS AERUGINOSA + | +CEFEPIME-------------- 2 S +CEFTAZIDIME----------- 4 S +CIPROFLOXACIN--------- =>4 R +GENTAMICIN------------ <=1 S +MEROPENEM------------- 0.5 S +PIPERACILLIN---------- 8 S +PIPERACILLIN/TAZO----- 8 S +TOBRAMYCIN------------ <=1 S + + ANAEROBIC CULTURE (Final [**2176-6-8**]): NO ANAEROBES ISOLATED. + +[**2176-6-3**] 3:46 pm BLOOD CULTURE +FINAL REPORT [**2176-6-9**]** Blood Culture, Routine (Final +[**2176-6-9**]):NO GROWTH. + +[**2176-6-3**] 3:46 pm URINE from CATHETER FINAL REPORT [**2176-6-5**]** +URINE CULTURE (Final [**2176-6-5**]): + Culture workup discontinued. Further incubation showed +contamination + with mixed fecal flora. Clinical significance of +isolate(s) + uncertain. Interpret with caution. + GRAM NEGATIVE ROD(S). >100,000 ORGANISMS/ML.. + +. + +Imaging Studies: + +CT abdomen/pelvis w/ contrast ([**6-3**]) +1. Pyelonephritis of the left kidney. No abscess. +2. The Foley catheter balloon is inflated in the penile urethra. +Small amount of gas within the bladder and the left distal +ureter are most likely related to the catheterization. +3. Small amount of free fluid is noted within the pelvis. + +CT abdomen/pelvis w/ contrast ([**6-9**]) +IMPRESSIONS: +1. Small, 3.6 x 1.2 x 4 cm fluid collection at the +posterior-superior aspect +of the bladder dome, with an enhancing rim, concerning for +abscess. The right +pelvic catheter does not terminate within this collection. +2. Trace residual free fluid in the mesentery of the pelvis. +Interval +resolution of free contrast material in the pelvis. + +CXR ([**6-7**]) +The NG tube tip is in the stomach. The right internal jugular +line tip is at mid SVC. There is interval improvement up to +almost complete resolution of pulmonary edema. The left +retrocardiac opacity is still present, most likely consistent +with left lower lobe atelectasis. Pleural effusion, bilateral, +is small, left more than right. + + +Brief Hospital Course: +87 yo man with history of prostate cancer s/p XRT, prior bladder +rupture, and dementia who was treated in the [**Hospital1 18**] MICU for a +second bladder rupture, bladder rupture repair and suprapubic +catheter placement, UTI, sepsis, and peritonitis who was +transfered to the Medicine service for management of his +post-surgical pain, resolving peritonitis, delirium, and heart +rate control. +. +# Bladder rupture, urosepsis, peritonitis +. +The pt had a history of bladder rupture s/p repair in [**1-/2175**] and +presented to this admission with evidence of new rupture on CT +in setting of vague abdominal pain, nausea, vomiting and +evolving shock. He likely has friable bladder tissue in setting +of XRT for prostate CA and prior rupture. At admission it was +unclear how long the rupture had been present, but may have been +related temporally to recent foley catheter change one week +prior. He had a history of MRSA, proteus, klebsiella and +pseudomonas UTIs, and thus was started on broad spectrum +antibiotics (vancomycin, cefepime, and gentamicin) at admission. +. +He was bolused with IV fluids overnight in the MICU and went to +the OR on the first hospital day. In the OR, a perforation in +the anterior bladder wall was closed. A suprapubic catheter was +placed in a posterior bladder wall perforation, and a JP drain +was placed in the peritoneum. Cultures were taken from the +peritoneal fluid and urine that grew out Pseudomonas sensitive +to cefepime and gent, resistent to cipro. After the surgery, +the output from the JP drain continued to decrease. Chemical +analysis was consistent with serum, rather than urine, and on +the basis of this it was felt that the bladder perforations were +successfully sealed. + +Post-operatively, he was treated with IV morphine and +acetaminophen for pain control. He was transfused 2 units PRBCs +for hematocrit 27, with appropriate bump. +The pt did go on to c/o some post-surgical pain. He continued to +drain clear urine from both the urethral and suprapubic +catheters. He had a CT scan on [**6-9**] to assess for a fluid +collection or abscess in the pelvic cavity, which showed a small +fluid collection that requires follow up CT. Thus he was cleared +for the removal of his JP drain. His surgical incision remained +clean, dry, and intact. He had two negative urine cx. The cx +of his peritoneal fluid sample taken on [**2176-6-4**] showed no growth +except for rare Pseudomonas Aeruginosa growth that were shown on +[**2176-6-12**] to be sensitive to Cefepim and Vancomycin. He was +continued on his regimen of IV Cefepim, Vancomycin, and +Gentamycin for 10 days to ensure adequate tx of his UTI and +peritonitis, but was switched to solely Cefepim coverage on +[**2176-6-12**] when the culture sensitivities returns. He had a PICC +line placed on [**2176-6-12**] for the completion of his 14 day course +of Cefepime. He did have mild urine leakage around his +suprapubic catheter, but this only lasted 3 days and Urology was +not concerned given that his catheters both continued to drain +clear urine. He is scheduled for a F/U pelvic CT scan to +reasscess the region concerning for a possible abscess, and he +is also scheduled for a F/U visit with his urologist Dr. [**Last Name (STitle) 770**] +for in 2 weeks. +. +# Delirium +W/R/T the pt's mental status, after his surgery, he became +increasingly agitated and disoriented. The delirium was felt to +be secondary to pain, recent surgery, infection, and narcotics +in the setting of baseline dementia. The pt. had been receiving +IV Dilaudid for pain. Overall the narcotics were used sparingly +and his infection was treated with [**Last Name (STitle) 17577**] broad spectrum abx. +Zyprexa was used in small doses for acute agitation with +adequate sedation. He was placed in soft restraints to protect +against the pt pulling out his NGT or either of his catheters or +drains. [**2176-6-7**] was the last time that the pt received Zyprexa +for agitation/delirium, and he became alert and oriented to +person, hospital name, and month/year since [**6-9**] and has been at +his baseline since then (he has some known dementia). He is +alert and oriented x3 on D/C. + +. +# Anemia + +W/R/T the pt's anemia as above, he received 2 units PRBCs +post-operatively for hematocrit of 27. His blood count then +stabilized and he did not require further transfusions. His +hemolytic work-up was negative. He stabilized in the low 30s +throughout his stay and has been stable. +. +# Atrial fibrillation + +The pt has a h/o atrial fibrillation controlled only by +Metoprolol and has not been anticoagulated due to his h/o +hemorrhage on coumadin. While in the hospital he had multiple +episodes of atrial fibrillation with RVR to 130-160s, typically +related to pain and stress. His metoprolol had been held due to +hypotension at admission, but was restarted to manage his RVR +when his blood pressure tolerated. He continued to have such +episodes of afib with RVR throughout his stay, and thus his +Metoprolol dose was increased to 50 mg Q 8H up from 25 mg [**Hospital1 **], +which his BP tolerated. With this increase in the metoprolol +maintained an average HR in the 70s and stopped having episodes +of RVR. He will need outpt F/U to assess any need to adjust this +regimen. + +. +# Diabetes mellitus II: + +The pt was placed on a humalog sliding scale with 15U NPH in the +AM, however was taken off of the NPH due to hypoglycemia in the +MICU. on the floor, the pt developed hyperglycemia to the 200's +and was consistently over 180, at which point 4 [**Location **] +was added and his sliding scale was increased to maintain better +glycemic control. He subsequently had lower blood glucose +levels overall, but still has some levels in the 200s and now +that he is not infected and will be having decreasing levels of +pain and stress, his insulin regimen will likely need to be +adjusted at the rehab facility with [**Location 17577**] finger sticks and +his primary care should f/u on this as well. +. +# Volume status/Blood pressure + +The pt has a h/o hypertension controlled on amlodipine and +metoprolol, but he was hypotensive at admission, at whcih point +he was hydrated aggressively with IV normal saline overnight and +post-operatively. As he recovered from hypotension and sepsis, +his blood pressure came up. Serial CXRs showed worsening +pulmonary edema and he was diuresed with boluses of IV Lasix, +which completely cleared his pulmonary edema. His outpatient +antihypertensives (except for Lisinopril) were restarted as +tolerated after he had recovered from peritonitis and urosepsis. + Lisinopril should be restarted as an outpatient as tolerated by +his blood pressure with the new adjustment to the metoprolol +levels. +. +# Nutrition: +W/R/T the pt's nutrition, given the pt's delirium, an NGT was +placed for tube feeds which were given continuously. He had a +speech and swallow consult with a swallow study and was noted to +be silently aspirating and was thus deemed unable to take POs +until he has rehab and a further evaluation. NGtube and PEG +were both considered, and it was decided to plan for discharge +with the NG tube with plans for speech and [**Hospital 42294**] with a goal of reachieving ability to take POs. +For now he has a feed rate of 40ml/hr but his goal is 60ml/hr. +The rate was slowed given recent NGT residuals, but he is on +Metoclopramide and and has recently begun a bowel regimen to +ensure that there is no backup causing these residuals. +Instrucitons are to hold for residuals over 150ml. +. +# Scrotal Edema and candidal infection +The pt also experienced extreme scrotal edema for being given +about 14 liters of IV fluid for his urospesis/hypotension. His +scrotum was elevated to decrease the edema, and has decreased +but is still an issue. He also developed a erythematous rash +around his scrotum and groin area which was treated with 2% +Miconazole powder. There is no warmth in this area or any +appearance of cellulitis. The plan is to continue to manage +with miconazole powder. +. +# Depression: +The pt has a h/o depression and had been on 10mg Lexapro per +night prior to admission. His home dose of Lexapro was held +during this admission given his delirium with the plan to +restart it as an outpatient. +. +The pt was known to be a full code status. +. +Signed: +[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 42295**] (Sub-Intern) pager number [**Serial Number 11736**] +[**Last Name (LF) **], [**First Name3 (LF) 1439**] (Resident) [**Numeric Identifier 16045**] +[**Last Name (LF) **], [**First Name3 (LF) 518**] (Attending) + + +Medications on Admission: +Cephalexin daily UTI ppx +NPH 15 units QAM +RISS +Heparin SC TID +Azo cranberry 450mg daily +Bisoprolol 5mg daily +Norvasc 5mg daily +Aspirin 81mg daily +Florastor 250mg [**Hospital1 **] +Tylenol 500mg TID +MVI [**Hospital1 **] +Lisinopril 5mg daily +Simvastatin 10mg QHS +Prilosec 20mg daily +Lexapro 20mg daily +MOM PRN constipation +Bisacodyl PRN constipation +Fleet's enema PRN constipation + +Discharge Medications: +1. Amlodipine 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Acetaminophen 500 mg Tablet Sig: Two (2) Tablet PO Q 8H +(Every 8 Hours) as needed for Pain/fever for 3 weeks. +3. Miconazole Nitrate 2 % Powder Sig: One (1) Appl Topical [**Hospital1 **] +(2 times a day). +Disp:*1 Appl* Refills:*2* +4. Oxybutynin Chloride 5 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) as needed for bladder pain. +Disp:*1 Tablet(s)* Refills:*0* +5. Ondansetron 4 mg IV Q8H:PRN nausea, vomiting +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO DAILY (Daily) as +needed for constipation. +Disp:*1 Tablet(s)* Refills:*0* +7. Metoprolol Tartrate 50 mg Tablet Sig: One (1) Tablet PO Q 8H +(Every 8 Hours). +Disp:*1 Tablet(s)* Refills:*2* +8. Docusate Sodium 50 mg/5 mL Liquid Sig: One (1) PO DAILY +(Daily). +Disp:*1 50 mg/5 ml* Refills:*2* +9. Insulin Glargine 100 unit/mL Solution Sig: Four (4) UNits +Subcutaneous at bedtime. +10. Cefepime 2 gram Recon Soln Sig: Two (2) g Intravenous twice +a day for 5 days. +11. Heparin (Porcine) 5,000 unit/mL Solution Sig: 5000 (5000) +Units Injection TID (3 times a day). +12. Metoclopramide 5 mg Tablet Sig: One (1) Tablet PO every six +(6) hours. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +Your primary Diagnoses Include: +Bladder rupture +Peritonitis +Urinary tract infection +sepsis + +Secondary Diagnoses +Delirium +Diabetes mellitus +Atrial fibrillation with episodes of rapid ventricular rate + + +Discharge Condition: +Stable. Afebrile. At his baseline mental status. Pain adequately +controlled on standing Tylenol. + + +Discharge Instructions: +You were admitted to the hospital for treatment of bladder +rupture and infection. You underwent surgery to repair the leak +in the bladder. Afterwards, you were treated with intravenous +antibiotics for infection in the space around the bladder. + +There have been changes to your medications as follows: + +1. Metoprolol increased to 50 mg Q 8H. This level may need to be +decreased in the future as recommended at followup with your +primary care doctor given you heart rate in the future. + +Scheduled appointments: +Please return to the [**Hospital1 18**] [**Hospital Ward Name 23**] Clinical center on [**2176-6-17**] +for your scheduled follow-up CT scan of the pelvis. +Plan for returning to the [**Hospital1 18**] for a followup appointment with +your Urologist, Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 770**] on Monday [**2176-6-17**] at 3 +PM. +The location of this appointment will be at the [**Hospital1 18**] [**Hospital Ward Name 5074**] [**Hospital Ward Name 23**] Building [**Location (un) **] Surgical Specialities. Please +call the phone number: ([**Telephone/Fax (1) 7707**] with quesitons about this +appointment. + +Please call your doctor or return to the emergency room for +fever > 101 deg F, worsening abdominal or bladder pain, or other +new symptoms concerning to you. + +Followup Instructions: +Newly-scheduled follow-ups: +- F/U CT 1 week after discharge to re-assess for abscess. CT +scheduled for [**2176-6-17**] at 8:15 AM at [**Location (un) **], [**Hospital Ward Name 5074**] [**Location (un) 470**]. +- F/U urology appointment: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 4653**], MD +Phone:[**Telephone/Fax (1) 5727**] Date/Time: [**2176-6-17**] 3:00PM. + + + +",22,2176-06-03 20:13:00,2176-06-12 17:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,SEPSIS," +87 yo man with history of prostate cancer s/p xrt, prior bladder +rupture, and dementia who was treated in the [**hospital1 18**] micu for a +second bladder rupture, bladder rupture repair and suprapubic +catheter placement, uti, sepsis, and peritonitis who was +transfered to the medicine service for management of his +post-surgical pain, resolving peritonitis, delirium, and heart +rate control. +. +# bladder rupture, urosepsis, peritonitis +. +the pt had a history of bladder rupture s/p repair in [**1-/2175**] and +presented to this admission with evidence of new rupture on ct +in setting of vague abdominal pain, nausea, vomiting and +evolving shock. he likely has friable bladder tissue in setting +of xrt for prostate ca and prior rupture. at admission it was +unclear how long the rupture had been present, but may have been +related temporally to recent foley catheter change one week +prior. he had a history of mrsa, proteus, klebsiella and +pseudomonas utis, and thus was started on broad spectrum +antibiotics (vancomycin, cefepime, and gentamicin) at admission. +. +he was bolused with iv fluids overnight in the micu and went to +the or on the first hospital day. in the or, a perforation in +the anterior bladder wall was closed. a suprapubic catheter was +placed in a posterior bladder wall perforation, and a jp drain +was placed in the peritoneum. cultures were taken from the +peritoneal fluid and urine that grew out pseudomonas sensitive +to cefepime and gent, resistent to cipro. after the surgery, +the output from the jp drain continued to decrease. chemical +analysis was consistent with serum, rather than urine, and on +the basis of this it was felt that the bladder perforations were +successfully sealed. + +post-operatively, he was treated with iv morphine and +acetaminophen for pain control. he was transfused 2 units prbcs +for hematocrit 27, with appropriate bump. +the pt did go on to c/o some post-surgical pain. he continued to +drain clear urine from both the urethral and suprapubic +catheters. he had a ct scan on [**6-9**] to assess for a fluid +collection or abscess in the pelvic cavity, which showed a small +fluid collection that requires follow up ct. thus he was cleared +for the removal of his jp drain. his surgical incision remained +clean, dry, and intact. he had two negative urine cx. the cx +of his peritoneal fluid sample taken on [**2176-6-4**] showed no growth +except for rare pseudomonas aeruginosa growth that were shown on +[**2176-6-12**] to be sensitive to cefepim and vancomycin. he was +continued on his regimen of iv cefepim, vancomycin, and +gentamycin for 10 days to ensure adequate tx of his uti and +peritonitis, but was switched to solely cefepim coverage on +[**2176-6-12**] when the culture sensitivities returns. he had a picc +line placed on [**2176-6-12**] for the completion of his 14 day course +of cefepime. he did have mild urine leakage around his +suprapubic catheter, but this only lasted 3 days and urology was +not concerned given that his catheters both continued to drain +clear urine. he is scheduled for a f/u pelvic ct scan to +reasscess the region concerning for a possible abscess, and he +is also scheduled for a f/u visit with his urologist dr. [**last name (stitle) 770**] +for in 2 weeks. +. +# delirium +w/r/t the pts mental status, after his surgery, he became +increasingly agitated and disoriented. the delirium was felt to +be secondary to pain, recent surgery, infection, and narcotics +in the setting of baseline dementia. the pt. had been receiving +iv dilaudid for pain. overall the narcotics were used sparingly +and his infection was treated with [**last name (stitle) 17577**] broad spectrum abx. +zyprexa was used in small doses for acute agitation with +adequate sedation. he was placed in soft restraints to protect +against the pt pulling out his ngt or either of his catheters or +drains. [**2176-6-7**] was the last time that the pt received zyprexa +for agitation/delirium, and he became alert and oriented to +person, hospital name, and month/year since [**6-9**] and has been at +his baseline since then (he has some known dementia). he is +alert and oriented x3 on d/c. + +. +# anemia + +w/r/t the pts anemia as above, he received 2 units prbcs +post-operatively for hematocrit of 27. his blood count then +stabilized and he did not require further transfusions. his +hemolytic work-up was negative. he stabilized in the low 30s +throughout his stay and has been stable. +. +# atrial fibrillation + +the pt has a h/o atrial fibrillation controlled only by +metoprolol and has not been anticoagulated due to his h/o +hemorrhage on coumadin. while in the hospital he had multiple +episodes of atrial fibrillation with rvr to 130-160s, typically +related to pain and stress. his metoprolol had been held due to +hypotension at admission, but was restarted to manage his rvr +when his blood pressure tolerated. he continued to have such +episodes of afib with rvr throughout his stay, and thus his +metoprolol dose was increased to 50 mg q 8h up from 25 mg [**hospital1 **], +which his bp tolerated. with this increase in the metoprolol +maintained an average hr in the 70s and stopped having episodes +of rvr. he will need outpt f/u to assess any need to adjust this +regimen. + +. +# diabetes mellitus ii: + +the pt was placed on a humalog sliding scale with 15u nph in the +am, however was taken off of the nph due to hypoglycemia in the +micu. on the floor, the pt developed hyperglycemia to the 200s +and was consistently over 180, at which point 4 [**location **] +was added and his sliding scale was increased to maintain better +glycemic control. he subsequently had lower blood glucose +levels overall, but still has some levels in the 200s and now +that he is not infected and will be having decreasing levels of +pain and stress, his insulin regimen will likely need to be +adjusted at the rehab facility with [**location 17577**] finger sticks and +his primary care should f/u on this as well. +. +# volume status/blood pressure + +the pt has a h/o hypertension controlled on amlodipine and +metoprolol, but he was hypotensive at admission, at whcih point +he was hydrated aggressively with iv normal saline overnight and +post-operatively. as he recovered from hypotension and sepsis, +his blood pressure came up. serial cxrs showed worsening +pulmonary edema and he was diuresed with boluses of iv lasix, +which completely cleared his pulmonary edema. his outpatient +antihypertensives (except for lisinopril) were restarted as +tolerated after he had recovered from peritonitis and urosepsis. + lisinopril should be restarted as an outpatient as tolerated by +his blood pressure with the new adjustment to the metoprolol +levels. +. +# nutrition: +w/r/t the pts nutrition, given the pts delirium, an ngt was +placed for tube feeds which were given continuously. he had a +speech and swallow consult with a swallow study and was noted to +be silently aspirating and was thus deemed unable to take pos +until he has rehab and a further evaluation. ngtube and peg +were both considered, and it was decided to plan for discharge +with the ng tube with plans for speech and [**hospital 42294**] with a goal of reachieving ability to take pos. +for now he has a feed rate of 40ml/hr but his goal is 60ml/hr. +the rate was slowed given recent ngt residuals, but he is on +metoclopramide and and has recently begun a bowel regimen to +ensure that there is no backup causing these residuals. +instrucitons are to hold for residuals over 150ml. +. +# scrotal edema and candidal infection +the pt also experienced extreme scrotal edema for being given +about 14 liters of iv fluid for his urospesis/hypotension. his +scrotum was elevated to decrease the edema, and has decreased +but is still an issue. he also developed a erythematous rash +around his scrotum and groin area which was treated with 2% +miconazole powder. there is no warmth in this area or any +appearance of cellulitis. the plan is to continue to manage +with miconazole powder. +. +# depression: +the pt has a h/o depression and had been on 10mg lexapro per +night prior to admission. his home dose of lexapro was held +during this admission given his delirium with the plan to +restart it as an outpatient. +. +the pt was known to be a full code status. +. +signed: +[**first name8 (namepattern2) **] [**last name (namepattern1) 42295**] (sub-intern) pager number [**serial number 11736**] +[**last name (lf) **], [**first name3 (lf) 1439**] (resident) [**numeric identifier 16045**] +[**last name (lf) **], [**first name3 (lf) 518**] (attending) + + + ","PRIMARY: [Septicemia due to pseudomonas] +SECONDARY: [Septic shock; Accidental puncture or laceration during a procedure, not elsewhere classified; Other suppurative peritonitis; Urinary tract infection, site not specified; Pulmonary congestion and hypostasis; Acute posthemorrhagic anemia; Rupture of bladder, nontraumatic; Severe sepsis; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Atrial fibrillation; Personal history of malignant neoplasm of prostate; Long-term (current) use of insulin; Gross hematuria; Unspecified essential hypertension; Depressive disorder, not elsewhere classified; Mononeuritis of lower limb, unspecified; Late effect of radiation; ; Other specified antibiotics causing adverse effects in therapeutic use; Pressure ulcer, lower back; Pressure ulcer, heel; Pressure ulcer, stage II; Pressure ulcer, stage I; Candidiasis of skin and nails; Edema of male genital organs]" +28223,121068.0,12930,2190-09-12,12929,187916.0,2190-05-30,Discharge summary,"Admission Date: [**2190-5-20**] Discharge Date: [**2190-5-30**] + + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 2387**] +Chief Complaint: +gangrenous toe + +Major Surgical or Invasive Procedure: +Lower extremity angiogram with balloon angioplasty and placement +of stent + + +History of Present Illness: +Mr. [**Known lastname 39714**] is an 89yo gentleman with dementia, PVD, diastolic +CHF, and AFib on coumadin admitted for work-up of gangrenous toe +and mental status changes. Of note, he had been taking increased +doses of percocet for the painful foot, and he had been +increasingly withdrawn in the setting of his son's death on +[**5-6**]. Shortly after admission to the floor, he was noted to be +unresponsive except to sternal rub; ABG was 7.07/120/225. A Code +Blue was called, and the patient was intubated for hypercarbic +respiratory failure. + +In the MICU, he was found to be febrile; cultures were +significant for a positive UA, and he was started on cipro. He +self-extubated himself during a spontaneous breathing trial and +did well without need for reintubation. Per his family, his +mental status at baseline is that he responds to questions but +is not oriented. + +Past Medical History: +Chronic Diastolic CHF (EF 45%) +PVD s/p R SFA stent [**2-/2190**], s/p PTA peroneal, s/p R +tarsometatarsal amputation +Tachy-brady syndrome s/p PPM +Atrial fibriallation on coumadin +CAD +CRI (baseline Cr 1.5-2.0) +h/o locally advanced prostate cancer +Anemia of chronic disease (colonoscopy and EGD unremarkable) +h/o lung nodules (recent CT scan with unchanged nodules on chest +CT - likely silicosis vs malignancy) +?? h/o miner's lung +Gout +dementia +CVA + +Allergies: NKDA + +PCP: [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 5456**] +Cardiologist: Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] + +Social History: +Worked as a coal miner. Has 24/7 care at home for daily +activities; 15 children. Not ambulating since his recent +amputation of toes on right foot. Needs help with daily +activities (eating, dressing). + + +Family History: +Non-contributory. + +Physical Exam: +VS- 100.0 158/52 54 20 100% RA +Gen- Awake, pleasant, responds slowly to some questions, not at +all to others, oriented to self but not to place or time. +Heent- MMM, anicteric, missing teeth +Neck- Supple, no LAD, healing IV wound L neck, JVP not elevated. + +Heart- S1, S2, RRR, I/VI systolic murmur. +Chest- Moving air well, no crackles. +Abd- soft, NT, ND, pos BS, no palpable masses +Ext- [**Last Name (un) **] bed pallor, no clubbing, no edema. Right toes have +been amputated; Left big toe is gangrenous, but no frank pus or +warmth. No LE edema. +Neuro- UE somewhat rigid with superimposed tremor. Head slumped +to the side. + +Pertinent Results: +[**2190-5-20**] 01:15PM BLOOD WBC-8.6 RBC-3.51* Hgb-9.5* Hct-31.2* +MCV-89 MCH-27.0 MCHC-30.3* RDW-17.5* Plt Ct-431 +[**2190-5-23**] 03:15AM BLOOD WBC-13.8*# RBC-3.49* Hgb-9.7* Hct-31.0* +MCV-89 MCH-27.6 MCHC-31.1 RDW-17.6* Plt Ct-196 +[**2190-5-30**] 05:00AM BLOOD WBC-5.9 RBC-3.20* Hgb-8.7* Hct-27.5* +MCV-86 MCH-27.2 MCHC-31.6 RDW-18.0* Plt Ct-381 +[**2190-5-20**] 01:15PM BLOOD PT-19.3* PTT-34.1 INR(PT)-1.8* +[**2190-5-30**] 05:00AM BLOOD PT-14.6* PTT-33.4 INR(PT)-1.3* +[**2190-5-20**] 01:15PM BLOOD Glucose-155* UreaN-43* Creat-2.5* Na-147* +K-5.6* Cl-105 HCO3-29 AnGap-19 +[**2190-5-30**] 05:00AM BLOOD Glucose-81 UreaN-16 Creat-1.5* Na-145 +K-4.0 Cl-106 HCO3-27 AnGap-16 +[**2190-5-20**] 01:15PM BLOOD ALT-63* AST-90* AlkPhos-99 TotBili-0.2 +[**2190-5-22**] 05:20AM BLOOD ALT-120* AST-121* LD(LDH)-404* AlkPhos-68 +TotBili-0.2 +[**2190-5-28**] 07:25AM BLOOD ALT-29 AST-22 +[**2190-5-20**] 01:15PM BLOOD Lipase-24 +[**2190-5-20**] 05:18PM BLOOD CK-MB-6 cTropnT-0.16* +[**2190-5-21**] 03:23AM BLOOD CK-MB-NotDone cTropnT-0.17* +[**2190-5-20**] 01:15PM BLOOD Albumin-3.6 Calcium-8.7 Phos-5.6*# Mg-2.6 +[**2190-5-30**] 05:00AM BLOOD Calcium-8.2* Phos-3.2 Mg-1.8 +[**2190-5-21**] 06:09PM BLOOD VitB12-GREATER TH Folate-GREATER TH +[**2190-5-24**] 05:50AM BLOOD %HbA1c-5.5 +[**2190-5-25**] 08:05AM BLOOD Triglyc-60 HDL-36 CHOL/HD-2.8 LDLcalc-51 +[**2190-5-21**] 06:09PM BLOOD TSH-2.9 +[**2190-5-20**] 01:15PM BLOOD ASA-NEG* Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +[**2190-5-21**] 01:28AM BLOOD Type-ART Temp-36.7 pO2-240* pCO2-106* +pH-7.11* calTCO2-36* Base XS-0 Intubat-NOT INTUBA +[**2190-5-21**] 02:09AM BLOOD Type-ART pO2-225* pCO2-120* pH-7.07* +calTCO2-37* Base XS-0 +[**2190-5-23**] 06:06AM BLOOD Type-ART pO2-180* pCO2-48* pH-7.37 +calTCO2-29 Base XS-2 +[**2190-5-20**] 01:10PM BLOOD Lactate-2.2* +[**2190-5-23**] 06:06AM BLOOD Lactate-1.0 +[**2190-5-21**] 02:09AM BLOOD freeCa-1.20 + +Urine Cx [**5-22**] Citrobacter freundii sensitive to cipro +Blood Cx [**5-20**], [**5-22**] negative +Resp Cx: no significant growth + +ECG: Paced, no acute changes + +Studies~ + +Left foot plain film [**2190-5-20**]: +Transverse fracture of the mid diaphysis of the second proximal +phalanx. + +CXR [**2190-5-20**]: Bilateral parenchymal opacities, for which CT of +the chest is recommended for further evaluation and to exclude +malignancy. + +CT Head [**2190-5-21**]: +There is no evidence of acute intracranial hemorrhage or mass +effect. Unchanged low-attenuation areas in the subcortical white +matter and focal low attenuations likely consistent with small +vessel disease and lacunar ischemic changes. +Persistent and unchanged right frontal subcortical area of low +density, likely consistent with sequela of an old ischemic +event. If there is no clinical contraindication, MRI of the head +with diffusion-weighted sequences may provide better +characterization of these findings. + +RUQ Ultrasound [**5-21**]: +1. Cholelithiasis with no signs of cholecystitis. +2. Trace of ascites. +3. Atrophic kidneys. + +Renal US [**5-24**]: +1. Bilateral atrophic kidneys without evidence of hydronephrosis +or renal calculi. +2. Right upper pole simple cyst measuring up to 1.2 cm. + +CXR [**5-25**]: +1. Interval worsening of the mild pulmonary edema. Unchanged +bilateral +multifocal pneumonia. +2. Increasing moderate right pleural effusion. + +LE Angiogram [**5-27**]: +1. Access was obtained in a treograde fashion in teh right +common +femoral artery. AN omniflush catheter was advanced to the level +of L2/L3 +and a dstal abdominal aortogram was prefromed. The abdominal +aorta had +moderate diffuse disease. The renal arteries were poorly seen. +The RCIA, +IIA and EIA were patent. The RCFA was patent and teh RLE was not +imaged +beyond that point. The LCIA, EIA and IIA were patent as was the +L CFA. +The LSFA had a 70% stenosis. The ominiflush catheter was then +advanced +over the [**Doctor Last Name 534**] over an angled gluide wire and selective +angiography of +the LLE was preformed. The popliteal artery was patent with mild +diffuse +disease. There was a high grade stenosis of the TPT and the AT +and the +PT were 100% occluded. There were diffuse high grade stenoses of +the +peroneal artery. The left DP and foot filled via collaterals +from the PA +artery. +2. Successful PTA of the L PA with a 3.0 balloon. Final +angiography +revealed a 20% residual stenosis and no dissection. (See PTA +comments) +3. Successful stenting of the LSFA with a 6.0 x 60 mm protege +stent +which was post dilate dto 6.0 with a admiral balloon. Final +angiography +revealed no residual stenosis in the stent, no dissection and +normal +flow. (See PTA comments) +FINAL DIAGNOSIS: +1. Peripheral vascular disease. +2. Stenting of the LSFA. +3. Successful PTA of the L PA + +Brief Hospital Course: +89yo gentleman with dementia, HTN, PVD, CAD, AFib (s/p PPM for +tachy-brady syndrome), and CKD who admitted with gangrenous toe, +found to have mental status changes upon arrival to the floor. + +# Mental status change/Hypercarbic respiratory failure +Shortly after admission to the hospital floor, the patient was +noted to be obtunded. An ABG showed significant hypercarbia to +120 and a code blue was called. The patient was intubated and +transferred to the MICU for further care. Within 48 hours of +intubation, the patient self-extubated during a spontaneous +breathing trial and did well on his own; he did not require +re-intubation. + +The precipitating event for his hypercarbic respiratory failure +was unclear. A CT of his head did not show any acute event. It +was noted that he had been taking increasing doses of percocet +just prior to his presentation, and there was concern that he +might have had narcotic induced hypoventilation. + +Through the rest of his course, his mental status was oriented +to person only. He responded to most simple questions. His +family felt that he was at his baseline. + +# Fevers: +The patient was febrile on [**5-22**], shortly after presentation +to the MICU. His cultures were significant for Citrobacter +freundi in his urine. He was started on ciprofloxacin for his +UTI on [**5-22**] x a 2 week course to be completed [**6-4**]. His +blood cultures were negative. Although subsequent CXRs were +read as possible pneumonia, his fevers resolved with treatment +of his UTI and he did not have clinical manifestations of +pneumonia. Upon review of his prior chest films and CT chest, +he has a long history of nodules and pulmonary opacities due to +silicosis. + +# Acute Renal Failure on Chronic Renal Insufficiency/ Acute on +chronic diastolic heart failure: +Patient's baseline creatinine ranges 1.5-2.0. At the time of +admission, his Cr was 2.5. His diuretics were held and he was +given several liters of fluid in the MICU and transfused one +unit of pRBCs. Renal ultrasound showed no evidence of +obstruction. His creatinine improved to 1.4 prior to his cath +and was 1.5 on the day of discharge. + +Although he initially appeared dehydrated on admission, Mr. +[**Known lastname 39714**] developed lower extremity edema and crackles on his exam +in the setting of receiving IV fluids for ARF and prior to his +catheterization. He was kept in the hospital after the +angiogram for diuresis. He was given IV lasix and then +transitioned to PO lasix. His home lasix dose was increased +from 40mg daily to 80mg daily to continue diuresis for his lower +extremity edema. + +**His blood will be drawn [**6-2**] and a BUN/Cr should be sent to +his primary care doctor so that his dose of lasix can be +adjusted as appropriate. He will likely need to be put back on +40mg lasix daily once his lower extremity has improved.** + +# Gangrenous left big toe/Peripheral vascular disease: +After the patient's renal function returned to baseline, he was +brought to the cath lab and underwent LE angiography with +balloon angioplasty and a stent to his LSFA. He was continued +on aspirin and plavix was started. + +There was no evidence of infection in his lower extremities. He +had recently completed 2 weeks of keflex prior to his admission. + Wound care was provided per wound care nursing recommendations. + The patient should follow-up with Dr. [**Last Name (STitle) **]. + +# Hypertension: +Mr. [**Known lastname 39714**] developed hypertensive urgency during his hospital +stay. The trigger for his elevated BPs was not clear, though +his systolic blood pressure was noted to be elevated 150s-170s +even before he became acutely hypertensive to 200 and was +transferred to the CCU. His pressures were acutely controlled +with hydralazine. + +His metoprolol was increased and he was started on norvasc. At +the time of discharge, his blood pressures were greatly improved +on this regimen with systolic pressures in the 130s to 150s. +His blood pressure regimen should continue to be adjusted as +needed as an outpatient. + +# Transaminitis: +Patient was noted to have a transaminitis upon admission. He +had a RUQ ultrasound that showed gallstones but no evidence of +cholecystitis. His transaminitis resolved with IV fluids and +his ALT/AST were normal at the time of discharge. + +# Anemia: +Patient's Hct was stable at 28-31. He received 1 unit of packed +red cells in the setting of ARF while he was in the MICU with an +appropriate increase in his Hct. His iron supplementation was +continued. + +# Coronary artery disease: +There was no evidence of active coronary disease. His ASA, +atorvastatin, and metoprolol were continued. + +# History of Atrial fibrillation: +Patient is s/p PPM for tachybrady syndrome. He was V-paced on +telemetry. +His coumadin was initially held in anticipation of angiography. +At the time of discharge, his coumadin was restarted. His INR +will be drawn on Wednesday to allow his coumadin to be adjusted +as needed since he is being sent home on ciprofloxacin, which +interacts with coumadin. + +# Dementia/Delirium: +After his extubation, the patient was felt to be at his baseline +as discussed above. His valproate, which he takes at home for +behavioral control, was continued. His wife was advised to +avoid narcotics because of the concern that the percocet had +been responsible for his hypoventilation. + +# Neurotic excoriations on neck: +Dermatology was consulted for ulcerated lesions on the patient's +neck and head. They felt that he had neurotic excoriations and +that the lesions would heal if he would stop picking at them. +He was given mitts to wear and the sores should be covered with +vaseline and then gauze to help prevent him from scratching +them. + +# Gout: continued allopurinol + +# Nutrition: Soft/dysphagia diet with nectar thickened liquid +per speech and swallow + +# Code: full (confirmed with wife) + +# Dispo: He was discharged to home, where he has 24 hour care as +well as a hospital bed and VNA. + +# Communication: Wife [**Name (NI) 382**] [**Name (NI) **] [**Telephone/Fax (1) 39715**]. + +# Note that the following medication changes were made: +- increased metoprolol to 150mg daily +- increased lasix to 80mg daily*** Please note that this dose +will probably need to be decreased down to 40mg daily in the +next week. +- started norvasc (amlodipine) 5mg daily +- started plavix (clopidogrel) 75mg daily +- started ciprofloxacin 500mg twice a day for 5 more days to +treat urine infection (last day to take is [**6-4**]) +- stop taking percocet or oxycodone as these medications may +have been responsible for making your breathing dangerously +slow. + +Medications on Admission: +ASA 81mg PO daily +Iron 65mg daily +Allopurinol 100mg PO daily +Colchicine .6mg PO daily +Divalproex 250mg PO bid +Tolterodine LA 4mg daily +Montelukast 10mg PO daily +Metoprolol XL 50mg daily +Atorvastatin 10mg PO daily +Docustate 100mg PO bid +Warfarin 2.5mg PO qhs +Lasix 40mg daily +oxycodone 1tab q4-6hours prn +megace 1 teaspoon daily +MVI +Keflex course [**2190-5-11**] + +Discharge Medications: +1. Allopurinol 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Montelukast 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Atorvastatin 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Valproate Sodium 250 mg/5 mL Syrup Sig: Two [**Age over 90 1230**]y +(250) mg PO Q12H (every 12 hours). +5. Multivitamins Tablet, Chewable Sig: One (1) Tablet, +Chewable PO once a day. +6. Iron 27 mg (Elemental) Tablet Sig: Two (2) Tablet PO once a +day. +7. Aspirin 81 mg Tablet Sig: One (1) Tablet PO once a day. +8. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM: adjust dose as directed by your primary doctor. +9. Docusate Sodium 50 mg/5 mL Liquid Sig: One Hundred (100) mg +PO BID (2 times a day). +10. Megestrol 400 mg/10 mL Suspension Sig: One (1) teaspoon PO +DAILY (Daily). +11. Metoprolol Succinate 50 mg Tablet Sustained Release 24 hr +Sig: Three (3) Tablet Sustained Release 24 hr PO once a day. +Disp:*90 Tablet Sustained Release 24 hr(s)* Refills:*0* +12. Amlodipine 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*1* +13. Clopidogrel 75 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*1* +14. Ciprofloxacin 500 mg Tablet Sig: One (1) Tablet PO Q12H +(every 12 hours) for 5 days: Last day to take is [**6-4**]. +Disp:*10 Tablet(s)* Refills:*0* +15. Furosemide 40 mg Tablet Sig: Two (2) Tablet PO ONCE (Once): +**you will probably need to decrease your dose to 40mg sometime +in the next week as directed by your physician**. +Disp:*60 Tablet(s)* Refills:*0* +16. Colchicine 0.6 mg Tablet Sig: One (1) Tablet PO once a day. + +17. Tolterodine 4 mg Capsule, Sust. Release 24 hr Sig: One (1) +Capsule, Sust. Release 24 hr PO once a day. + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Primary Diagnosis: Peripheral vascular disease +Secondary Diagnoses: Dry gangrene, Hypercarbic respiratory +failure, Mental status change, Hypertension, Atrial fibrillation + + +Discharge Condition: +Afebrile, vital signs stable, mental status at baseline +(oriented to person but not place or time) + + +Discharge Instructions: +You were admitted with dry gangrene of your big toe. There is +no sign of infection. The gangrene is there because of poor +blood flow to the foot. You had an angiogram and a stentwas +placed to help the blood flow to your foot. + +1. Please take all medications as prescribed. Note that the +following medication changes were made: +- increased metoprolol to 150mg daily +- increased lasix to 80mg daily*** Please note that this dose +will probably need to be decreased down to 40mg daily in the +next week. +- started norvasc (amlodipine) 5mg daily +- started plavix (clopidogrel) 75mg daily +- started ciprofloxacin 500mg twice a day for 5 more days to +treat urine infection (last day to take is [**6-4**]) +- stop taking percocet or oxycodone as these medications may +have been responsible for making your breathing dangerously +slow. + +2. Please attend all follow-up appointments. + +3. Please call your doctor or return to the hospital if you +develop chest pain, palpitations, fevers, any change in the +wounds on your feet (including redness or pus), or any other +concerning symptom. + +***You need to call Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 34604**] office on the afternoon +of Wednesday, [**6-2**] to follow up on your bloodwork. Dr. +[**Last Name (STitle) 5456**] may adjust your dose of coumadin (also called warfarin) +or your dose of lasix depending on the results of your +bloodwork.*** + +Followup Instructions: +1. Please call your primary doctor and set up an appointment for +the next 2-3 weeks: Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) 5456**] [**Telephone/Fax (1) 5457**]. + +2. Please call Dr. [**Last Name (STitle) **] for an appointment in the next 4 weeks: +[**Telephone/Fax (1) 7960**]. + +3. Please keep your previously scheduled appointments: +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1244**], MD Phone:[**Telephone/Fax (1) 1237**] +Date/Time:[**2190-6-18**] 10:15 + + +Completed by:[**2190-5-30**]",105,2190-05-20 15:55:00,2190-05-30 19:17:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ALTERED MENTAL STATUS," +89yo gentleman with dementia, htn, pvd, cad, afib (s/p ppm for +tachy-brady syndrome), and ckd who admitted with gangrenous toe, +found to have mental status changes upon arrival to the floor. + +# mental status change/hypercarbic respiratory failure +shortly after admission to the hospital floor, the patient was +noted to be obtunded. an abg showed significant hypercarbia to +120 and a code blue was called. the patient was intubated and +transferred to the micu for further care. within 48 hours of +intubation, the patient self-extubated during a spontaneous +breathing trial and did well on his own; he did not require +re-intubation. + +the precipitating event for his hypercarbic respiratory failure +was unclear. a ct of his head did not show any acute event. it +was noted that he had been taking increasing doses of percocet +just prior to his presentation, and there was concern that he +might have had narcotic induced hypoventilation. + +through the rest of his course, his mental status was oriented +to person only. he responded to most simple questions. his +family felt that he was at his baseline. + +# fevers: +the patient was febrile on [**5-22**], shortly after presentation +to the micu. his cultures were significant for citrobacter +freundi in his urine. he was started on ciprofloxacin for his +uti on [**5-22**] x a 2 week course to be completed [**6-4**]. his +blood cultures were negative. although subsequent cxrs were +read as possible pneumonia, his fevers resolved with treatment +of his uti and he did not have clinical manifestations of +pneumonia. upon review of his prior chest films and ct chest, +he has a long history of nodules and pulmonary opacities due to +silicosis. + +# acute renal failure on chronic renal insufficiency/ acute on +chronic diastolic heart failure: +patients baseline creatinine ranges 1.5-2.0. at the time of +admission, his cr was 2.5. his diuretics were held and he was +given several liters of fluid in the micu and transfused one +unit of prbcs. renal ultrasound showed no evidence of +obstruction. his creatinine improved to 1.4 prior to his cath +and was 1.5 on the day of discharge. + +although he initially appeared dehydrated on admission, mr. +[**known lastname 39714**] developed lower extremity edema and crackles on his exam +in the setting of receiving iv fluids for arf and prior to his +catheterization. he was kept in the hospital after the +angiogram for diuresis. he was given iv lasix and then +transitioned to po lasix. his home lasix dose was increased +from 40mg daily to 80mg daily to continue diuresis for his lower +extremity edema. + +**his blood will be drawn [**6-2**] and a bun/cr should be sent to +his primary care doctor so that his dose of lasix can be +adjusted as appropriate. he will likely need to be put back on +40mg lasix daily once his lower extremity has improved.** + +# gangrenous left big toe/peripheral vascular disease: +after the patients renal function returned to baseline, he was +brought to the cath lab and underwent le angiography with +balloon angioplasty and a stent to his lsfa. he was continued +on aspirin and plavix was started. + +there was no evidence of infection in his lower extremities. he +had recently completed 2 weeks of keflex prior to his admission. + wound care was provided per wound care nursing recommendations. + the patient should follow-up with dr. [**last name (stitle) **]. + +# hypertension: +mr. [**known lastname 39714**] developed hypertensive urgency during his hospital +stay. the trigger for his elevated bps was not clear, though +his systolic blood pressure was noted to be elevated 150s-170s +even before he became acutely hypertensive to 200 and was +transferred to the ccu. his pressures were acutely controlled +with hydralazine. + +his metoprolol was increased and he was started on norvasc. at +the time of discharge, his blood pressures were greatly improved +on this regimen with systolic pressures in the 130s to 150s. +his blood pressure regimen should continue to be adjusted as +needed as an outpatient. + +# transaminitis: +patient was noted to have a transaminitis upon admission. he +had a ruq ultrasound that showed gallstones but no evidence of +cholecystitis. his transaminitis resolved with iv fluids and +his alt/ast were normal at the time of discharge. + +# anemia: +patients hct was stable at 28-31. he received 1 unit of packed +red cells in the setting of arf while he was in the micu with an +appropriate increase in his hct. his iron supplementation was +continued. + +# coronary artery disease: +there was no evidence of active coronary disease. his asa, +atorvastatin, and metoprolol were continued. + +# history of atrial fibrillation: +patient is s/p ppm for tachybrady syndrome. he was v-paced on +telemetry. +his coumadin was initially held in anticipation of angiography. +at the time of discharge, his coumadin was restarted. his inr +will be drawn on wednesday to allow his coumadin to be adjusted +as needed since he is being sent home on ciprofloxacin, which +interacts with coumadin. + +# dementia/delirium: +after his extubation, the patient was felt to be at his baseline +as discussed above. his valproate, which he takes at home for +behavioral control, was continued. his wife was advised to +avoid narcotics because of the concern that the percocet had +been responsible for his hypoventilation. + +# neurotic excoriations on neck: +dermatology was consulted for ulcerated lesions on the patients +neck and head. they felt that he had neurotic excoriations and +that the lesions would heal if he would stop picking at them. +he was given mitts to wear and the sores should be covered with +vaseline and then gauze to help prevent him from scratching +them. + +# gout: continued allopurinol + +# nutrition: soft/dysphagia diet with nectar thickened liquid +per speech and swallow + +# code: full (confirmed with wife) + +# dispo: he was discharged to home, where he has 24 hour care as +well as a hospital bed and vna. + +# communication: wife [**name (ni) 382**] [**name (ni) **] [**telephone/fax (1) 39715**]. + +# ","PRIMARY: [Atherosclerosis of native arteries of the extremities with gangrene] +SECONDARY: [Acute respiratory failure; Urinary tract infection, site not specified; Chronic diastolic heart failure; Acute kidney failure, unspecified; Malignant essential hypertension; Drug-induced delirium; Hyperosmolality and/or hypernatremia; Congestive heart failure, unspecified; Chronic kidney disease, unspecified; Other specified analgesics and antipyretics causing adverse effects in therapeutic use; Other nonspecific abnormal serum enzyme levels; Pure hypercholesterolemia; Gout, unspecified; Anemia of other chronic disease; Atrial fibrillation; Cardiac pacemaker in situ; Pneumoconiosis due to other silica or silicates; Other amputation stump complication]" +28259,111485.0,12626,2188-10-02,12610,113482.0,2188-09-08,Discharge summary,"Admission Date: [**2188-8-21**] Discharge Date: [**2188-9-8**] + +Date of Birth: [**2111-12-1**] Sex: M + +Service: MEDICINE + +Allergies: +Phenytoin / Decadron + +Attending:[**First Name3 (LF) 7223**] +Chief Complaint: +Meningioma + +Major Surgical or Invasive Procedure: +[**2188-8-20**]: Left Craniotomy for Meningioma with reconstruction +[**2188-8-31**]: G-tube placement + +History of Present Illness: +76-year-old male with history of recurrent meningioma s/p +bifrontal craniotomy with cranioplasty and bone flap [**2188-8-21**], +transferred from TICU for further management of post-operative +atrial fibrillation. Patient has baseline sinus bradycardia and +underwent ablation after presentation with tachyarrythmia on +[**2188-7-16**]. Patient unable to give history. + +Past Medical History: +1. Atypical Reccurent Right Frontal Meningioma: Symptoms began +in [**2180-6-22**] per [**First Name8 (NamePattern2) 38984**] [**Last Name (NamePattern1) **] ""when he became forgetful and +sluggish. Initially he was treated for depression. A head MRI +showed a large dura-based mass in the right frontal brain. A +resection was done by [**Name6 (MD) 1528**] Cares, MD [**First Name (Titles) **] [**Last Name (Titles) **] [**Hospital1 38994**]. Pathology was atypical meningioma. He did well until +[**10-22**] when the mass recurred. He had a second resection on +[**2182-1-9**] by Dr. [**Last Name (STitle) 38985**]. This was followed with involved-field +cranial irradiation by [**First Name8 (NamePattern2) 636**] [**Last Name (NamePattern1) 38986**], MD [**First Name (Titles) **] [**Last Name (Titles) **] [**Hospital1 **] +from [**Month (only) **] to [**2182-3-22**] to 5760 cGy. A follow up MRI on [**2183-6-26**] +showed a 0.5-mm dural based nodular enhancement and he was +referred here for SRS. Surveillance MRI on [**2184-12-8**] revealed +growth of the meningioma in the superior margin of the surgical +cavity invading the skull. He underwent craniectomy on [**2185-1-26**] +by [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD [**First Name (Titles) **] [**Last Name (Titles) 38987**]. There had been invasion +into the inner and outer tables of the skull. A piece of Duagen +dural substitute was placed over the dural defect and then +Methyl Methacrylate cranioplasty was placed over the skull +defect. Pathology revealed atypical meningioma."" Underwent +cyberknife therapy in [**2-27**]. He has been maintained on temodar +(chemo) 25mg/m2. +2. Atrial fibrillation: Known to Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] and followed +by Dr. [**Last Name (STitle) 16958**]. +3. GERD +4. OA of knee +5. Hypothyroid + + +Social History: +Married with two children. Used to smoke a pack a day but quit +in [**2151**]. Used to drink beer but stopped when he was put on +Coumadin. Mother died at 80 from stroke. Father died at 60's, +unclear cause. Bother died 60 from lung cancer. + +Family History: +Non-contributory + +Physical Exam: +Gen: elderly male in NAD. Oriented x 1. Mood, affect +appropriate. +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. +CV: Regular rate, normal S1, S2. No m/r/g. No thrills, lifts. No +S3 or S4. +Chest: Resp were unlabored, no accessory muscle use. Poor air +flow bases bilateral. No wheezes or crackles. +Abd: Soft, NTND. PEG tube inplace. No HSM or tenderness. +Ext: No c/c/e. +Skin: No stasis dermatitis, ulcers, scars. + +Pertinent Results: +[**2188-8-22**] Echocardiogram: The left atrium is mildly dilated. There +is mild symmetric left ventricular hypertrophy. The left +ventricular cavity is unusually small. Overall left ventricular +systolic function is normal (LVEF 60%). The right ventricular +cavity is dilated with depressed free wall contractility. There +are focal calcifications in the aortic arch. The aortic valve +leaflets (3) are mildly thickened but aortic stenosis is not +present. No aortic regurgitation is seen. The mitral valve +leaflets are mildly thickened. There is no mitral valve +prolapse. The estimated pulmonary artery systolic pressure is +normal. There is a small pericardial effusion. There is an +anterior space which most likely represents a fat pad. There are +no echocardiographic signs of tamponade. +. +Compared with the findings of the prior study (images reviewed) +of [**2188-7-15**], the findings are similar. +. +Head CT [**2188-8-31**]: Multifocal intraparenchymal hemorrhage +centered within the right frontal lobe with surrounding edema is +relatively unchanged when compared to prior exam. A small amount +of extra-axial hemorrhage along the right frontal craniotomy is +stable in appearance as well. Areas of pneumocephalus near the +right frontal craniotomy mesh is persistent. There is no shift +of normally midline structures. The ventricle configuration is +unchanged. Hypodensity in the periventricular and subcortical +white matter reflects chronic microvascular and vascular +ischemic changes. Secretions in the right frontal sinus is +unchanged. +. +MRI [**2188-8-22**]: Status post interval resection of right frontal +scalp mass and the contiguous extra-axial enhancing lesions. +There is stable enhancing heterogeneous tissue in the inferior +right frontal lobe. There are findings suggestive of ischemia in +the right frontal lobe which is new compared to the prior study +of [**2188-8-21**]. There is a new mesh cranioplasty in the right +frontal region. +. +Labs on Admission: +[**2188-8-21**] 11:30AM BLOOD WBC-2.5* RBC-3.39* Hgb-11.0* Hct-29.7* +MCV-87 MCH-32.5* MCHC-37.1* RDW-14.1 Plt Ct-202 +[**2188-8-21**] 08:20AM BLOOD PT-23.0* PTT-33.7 INR(PT)-2.2* +[**2188-8-21**] 05:45PM BLOOD Glucose-196* UreaN-15 Creat-1.2 Na-142 +K-3.9 Cl-105 HCO3-26 AnGap-15 +[**2188-8-21**] 05:45PM BLOOD Calcium-10.0 Phos-3.3 Mg-2.5 +. +Labs on Discharge: + + +Brief Hospital Course: +Patient was electively admitted on [**8-21**] for a planned surgical +resection and esthetic reconstruction of his left cranium for +recurrent meningioma. On admission, his coagulation studies +were elevated, requiring the use of FFP infusion and vitamin K +infusion to correct prior to surgery. This was done +uneventfully, and surgery proceded. Intraoperatively, he had +several episodes of atrial fibrillation with rapid ventricular +response, which was refractory to cardioversion. He also +underwent an intraoperative TEE for further interrogation of +this process. Post-operatively, he was admitted to the ICU for +this reason, and cardiology consulted for control of his atrial +fibrillation he was started on an Amiodarone drip and Diltiazem +drips which eventually converted him. He remained abulic, +followed commands inconsistently and answered in one word +answers. +. +# Atrial Fibrillation: On [**8-27**] he was transferred to the step +down unit. On [**8-27**]: Back into afib on Esmolol. On [**8-29**]: amio 200 +[**Hospital1 **], LFTs wnl; back in afib. Lopressor 37.5mg PO BID. On [**2188-8-29**], +patient was transferred from trauma SICU to medicine cardiology +service. On arrival, he was in atrial fibrillation with RVR. Per +cardiology recs, he was given acebutolol 200mg via the NG tube. +Overnight, patient pulled out his NG tube. Given that he had +failed swallow studies twice in the previous week, he was not +able to take any medications by mouth. Plan was to give patient +IV beta-blockers as needed until a PEG tube was placed. On the +morning of [**2188-8-30**], patient was given metoprolol IV 5mg x1 for +atrial flutter with heart rate in 130s. Patient converted back +to sinus rhythm. On [**2188-9-1**] patient re-entered A Fib with RVR. +Patient was started on Acebutolol, Amiodarone 100mg qd and +digoxin 0.125mg. Metoprolol was not started as patient become +bradycardiac last time he converted. However, patient did not +convert with Acebutolol titrated up to 400mg [**Hospital1 **] consequently we +started Metoprolol. Patient converted on [**2188-9-6**] when titrated +to Metoprolol 100mg [**Hospital1 **]. No significant pauses or brady on +conversion. Patient recently had ablation in [**6-29**]. Pacemaker +placement not an ideal option as patient will require multiple +MRI for meningioma resection follow-up. +- Discharge on the following medications for rate control: +Metroprolol 75mg po BID, Amiodarone 100mg po qd, Digoxin +0.125mcg po every other day. +- Started Aspirin 81 mg, Neurosurgery stated this was ok. +**** Per neurosurgery, need to wait 1 month before +anticoagulation can be started due to recent craniotomy. Patient +is a candidate for anti-coagulation, was in A Fib with AVR +during hospitliazation. In 1 month need to discuss with +Neurosurgery and Cardiology re-starting anti-coagulation **** +. +# s/p frontal craniotomy: Of note, on [**2188-8-30**] plastic surgery +noted fluid build up at the incision site on frontal region. +Fluid was cultured and final report was no growth. Patient +received vancomycin for a 5 day course given that infection to +that area could be devastating. Kept head of bed elevated. +Continued Keppra for seizure prophylaxis. Patient has follow-up +appointments with Neurosurgery and Plastic surgery (will be +removing sutures). +. +# FEN: Patient has failed swallow study twice. Patient pulled +out NG tube night of [**2188-8-29**]. G tube placed [**2188-8-31**]. On tube +feeds with banana flakes secondary to bowel incontinence. +- Diet order per nutrition in page 1 +- discontinue banana flakes if patient becomes constipated +- peg site needs to changed daily with dry dressing +. +# Hypothyroidism: Repeat TSH 1.3, however free T4 remained +elevated at 1.9. Decreased Levothyroxine from 50mcg to 37.5 mcg. + +- Recheck TSH and free T4 in 1 month +. +# Hematuria: Urine culture negative. Repeat Ua no RBC. Hematuria +most likely secondary to trauma from patient pulling at foley. +Condom cath did not work, patient currently incontinent. +Discharge on foley. When patient becomes more oriented can d/c +foley +- recheck Ua for hematuria in [**1-23**] months +. +# DM: Morning NPH units increased to 14 from 12 as blood sugars +slightly elevated.Can adjust sliding scale at rehab as +appropriate. +. +#. Hypertension: Well-controlled throughout admission. Continued +lisinopril 10mg PO daily, for rate control patient on Metoprolol +75 mg [**Hospital1 **] with hold parameters. +. +# Code Status: Full, confirmed with wife + + +Medications on Admission: +1. Amiodorone (200 mg daily) +2. Coumadin [Warfarin] (stopped [**2188-8-17**]) +3. Levoxyl (50mcg daily) +4. Lisinopril [Prinivil, Zestril] (10 mg daily) +5. Metoprolol succinate [Toprol XL] (25 mg daily) +6. Neurontin (Gabapentin)(400 mg [**Hospital1 **]) +7. Sanctura 20 mg [**Hospital1 **]) +8. Pepcid (Famotidine)(20 mg daily) + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +Primary Diagnosis: +Meningioma +Atrial fibrillation with RVR +. +Secondary Diagnosis: +Hypothyroidism +Diabetes +GERD + + +Discharge Condition: +Vitals stable, sinus rythm. + + +Discharge Instructions: +You were admitted on [**2188-8-21**] for removal of a meningioma. During +the hospital course you were transferred to the cardiology +service for further management of a fast heart rhythm. You +eventually converted to sinus rythym. +. +We have made changes to your medications please take them as +directed. +. +Please attend your follow-up appointments as listed: +1) You have an appointment with Plastic Surgery Clinic on +[**2188-9-12**] 01:30p [**Hospital6 29**], [**Location (un) **]. They will be +removing your sutures. +2) You have an appointment with Radiology on [**2188-10-7**] 08:30a XCT +[**Apartment Address(1) 9394**] [**Hospital Ward Name **] CC CLINICAL CENTER, [**Location (un) **] RADIOLOGY to +have a CT head. Immediately following you have an appointment +with Neurosurgery on [**2188-10-7**] 9:30 am with Dr. [**Last Name (STitle) **],[**First Name3 (LF) **] +M. LM [**Hospital Unit Name **], [**Location (un) **] NEUROSURGERY WEST. You will not +need an MRI of the brain, as this was done during your hospital +stay. If you have any questions there number is [**Telephone/Fax (1) 1669**]. +3) Follow-up with your Cardiologist, Dr. [**Last Name (STitle) **] [**Telephone/Fax (1) 62**] on +[**10-16**] at 10:20am. His office is at [**Hospital6 29**], [**Location (un) **] CC7 CARDIOLOGY +4) Follow with primary care doctor Mr. [**Name13 (STitle) **] in [**2-25**] weeks. +Have [**Hospital **] rehab call [**Telephone/Fax (1) 38995**] to make an appointment. + +. +Call your primary care doctor or go to the ER if you experience +rapid heart rate, feeling dizzy, pass out, chest pain, shortness +of breath or any other symptoms. +. +The following discharge Instructions have been provided by +Neurosurgery regarding your surgery: +?????? Unless directed by your doctor, do not take any +anti-inflammatory medicines such as Motrin, Advil, and Ibuprofen +etc. +- If you have been prescribed an anti-seizure medicine, take it +as prescribed and follow up with laboratory blood drawing as +ordered. +- Clearance to drive and return to work will be addressed at +your post-operative office visit. + +CALL YOUR SURGEON IMMEDIATELY IF YOU EXPERIENCE ANY OF THE +FOLLOWING +- New onset of tremors or seizures. +- Any confusion or change in mental status. +- Any numbness, tingling, weakness in your extremities. +- Pain or headache that is continually increasing, or not +relieved by pain medication. +- Any signs of infection at the wound site: redness, swelling, +tenderness, or drainage. +- Fever greater than or equal to 101?????? F. + + + + + +Followup Instructions: +1) You have an appointment with Plastic Surgery Clinic on [**8-23**] 1:30pm at [**Hospital Ward Name 23**] Building [**Location (un) 470**]. They will be removing +your sutures. +. +2) You have an appointment with Radiology on [**2188-10-7**] 08:30a XCT +[**Apartment Address(1) 9394**] [**Hospital Ward Name **] CC CLINICAL CENTER, [**Location (un) **] RADIOLOGY to +have a CT head. Immediately following you have an appointment +with Neurosurgery on [**2188-10-7**] 9:30 am with Dr. [**Last Name (STitle) **],[**First Name3 (LF) **] +M. LM [**Hospital Unit Name **], [**Location (un) **] NEUROSURGERY WEST. You will not +need an MRI of the brain, as this was done during your hospital +stay. If you have any questions there number is [**Telephone/Fax (1) 1669**]. +. +3) Follow-up with your Cardiologist, Dr. [**Last Name (STitle) **] [**Telephone/Fax (1) 62**] on +[**10-16**] at 10:20am. His office is at [**Hospital6 29**], [**Location (un) **] CC7 CARDIOLOGY +. +4) Follow with primary care doctor Mr. [**Name13 (STitle) **] in [**2-25**] weeks. +Have rehab call [**Telephone/Fax (1) 38995**] to make an appointment. + + + +Completed by:[**2188-9-8**]",24,2188-08-21 12:30:00,2188-09-08 15:30:00,ELECTIVE,PHYS REFERRAL/NORMAL DELI,REHAB/DISTINCT PART HOSP,MENINGIOMA/SDA," +patient was electively admitted on [**8-21**] for a planned surgical +resection and esthetic reconstruction of his left cranium for +recurrent meningioma. on admission, his coagulation studies +were elevated, requiring the use of ffp infusion and vitamin k +infusion to correct prior to surgery. this was done +uneventfully, and surgery proceded. intraoperatively, he had +several episodes of atrial fibrillation with rapid ventricular +response, which was refractory to cardioversion. he also +underwent an intraoperative tee for further interrogation of +this process. post-operatively, he was admitted to the icu for +this reason, and cardiology consulted for control of his atrial +fibrillation he was started on an amiodarone drip and diltiazem +drips which eventually converted him. he remained abulic, +followed commands inconsistently and answered in one word +answers. +. +# atrial fibrillation: on [**8-27**] he was transferred to the step +down unit. on [**8-27**]: back into afib on esmolol. on [**8-29**]: amio 200 +[**hospital1 **], lfts wnl; back in afib. lopressor 37.5mg po bid. on [**2188-8-29**], +patient was transferred from trauma sicu to medicine cardiology +service. on arrival, he was in atrial fibrillation with rvr. per +cardiology recs, he was given acebutolol 200mg via the ng tube. +overnight, patient pulled out his ng tube. given that he had +failed swallow studies twice in the previous week, he was not +able to take any medications by mouth. plan was to give patient +iv beta-blockers as needed until a peg tube was placed. on the +morning of [**2188-8-30**], patient was given metoprolol iv 5mg x1 for +atrial flutter with heart rate in 130s. patient converted back +to sinus rhythm. on [**2188-9-1**] patient re-entered a fib with rvr. +patient was started on acebutolol, amiodarone 100mg qd and +digoxin 0.125mg. metoprolol was not started as patient become +bradycardiac last time he converted. however, patient did not +convert with acebutolol titrated up to 400mg [**hospital1 **] consequently we +started metoprolol. patient converted on [**2188-9-6**] when titrated +to metoprolol 100mg [**hospital1 **]. no significant pauses or brady on +conversion. patient recently had ablation in [**6-29**]. pacemaker +placement not an ideal option as patient will require multiple +mri for meningioma resection follow-up. +- ","PRIMARY: [Benign neoplasm of cerebral meninges] +SECONDARY: [Cerebral edema; Atrial flutter; Hemorrhage complicating a procedure; Unspecified protein-calorie malnutrition; Injury to bladder and urethra, without mention of open wound into cavity; Hyperosmolality and/or hypernatremia; Atrial fibrillation; Sinoatrial node dysfunction; Congestive heart failure, unspecified; ; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Unspecified essential hypertension; Unspecified acquired hypothyroidism; Esophageal reflux; Osteoarthrosis, localized, not specified whether primary or secondary, lower leg; Long-term (current) use of anticoagulants; Unspecified accident; Personal history of irradiation, presenting hazards to health; Personal history of tobacco use; Anemia, unspecified; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation]" +28933,118513.0,21653,2170-08-07,21652,190604.0,2170-04-20,Discharge summary,"Admission Date: [**2170-4-7**] Discharge Date: [**2170-4-20**] + +Date of Birth: [**2136-7-24**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 3913**] +Chief Complaint: +Hypotension + +Major Surgical or Invasive Procedure: +None. + +History of Present Illness: +33 year old male with h/o large B-cell lymphoma status post +allogenic stem cell transplant in [**2166**], complicated by severe +graft versus host disease of the skin and oral mucousa requiring +TPN, recent PE on Lovenox and recent admission for shortness of +breath and [**Female First Name (un) **] fungemia. He presented to [**Hospital 3242**] clinic today +with shortness of breath, malaise and fever. Also c/o dull +chest ache across entire chest without any pain or palpitations. +Denies pluiritic cp. +nonproductive cough. Fever to 102 AM of +admisison. +nausea and emesis X 1, one day PTA. +. +Initial vitals T 103, BP 114/88 HR 160 and 91%RA. He was given +6 mg adenosine with brief slowing of HR to 120s and ?Flutter +waves. He was given 2L IVF and underwent CTA to eval for PE. +He also received his outpt dose of 50mg metoprolol. On return to +the floor from CT, HR 135, SBP 75. The pt was transferred to +the MICU for further mgmt. + +Past Medical History: +(No changes since last admission) +# Large B cell lymphoma, s/p sibling-matched allogenic SCT in +[**6-/2167**] +- c/b severe GVHD of skin, GI/mouth +- had been receiving photopheresis -> stopped, now on rituxan +- TPN dependent (via PICC) +# Migraines +# h/o vaso-vagal syncope with blood draws +# h/o bacteremia +- coagulase neg Staph [**10-5**] and [**1-15**] +- Step Viridans [**1-15**] +- tx w/ 6wks of vancomycin; pheresis catheter was removed +- vancomycin started [**1-19**] +- TEE deferred given severe GI GVHD +# Steroid myopathy +# Moraxella sinusitis +- + sputum [**12/2090**], s/p 10d levaquin +# Cardiomyopathy +- TTE [**4-5**] EF 45-50% +- Likely multifactorial: chemotherapy, radiation, GVHD, +tachycardia +# Fungemia with [**Female First Name (un) **] [**Female First Name (un) 29361**], in process of treatment with +caspofungin +. +ONCOLOGIC HISTORY: +The patient was diagnosed with diffuse large B-cell lymphoma in + +[**9-/2165**] and treated with eight cycles of R-CHOP and 25 doses of + +XRT, finished in 6/[**2165**]. In [**6-/2166**], relapsed with +disease found in periaortic lymph nodes and in the spleen. He +received one cycle of ICE chemotherapy on [**2166-8-11**], underwent +autologous stem cell transplant and was discharged [**2166-11-11**]. +Follow up PET scan on [**2167-1-30**] demonstrated recurrent persistent +uptake in the spleen, mesentery, and with new liver and +pulmonary lesions. Liver biopsy demonstrated diffuse large +B-cell lymphoma and he was treated with three weekly doses of +Rituxan but continued to progress. He was treated with salvage +therapy with one cycle of MINE chemotherapy as an inpatient +starting [**2167-4-23**] and CT scan demonstrated response in the lung +and liver with stable disease in the spleen. The patient was +admitted for a second cycle of MINE +chemotherapy on [**2167-6-4**]. He received a nonmyeloablative +sibling-matched allogeneic SCT in 8/[**2166**]. He has had severe +chronic GVHD of the skin and oropharyngeal mucosa; he is +currently undergoing Rituxan weekly x4 for GVHD, last completed +at end of [**Month (only) 958**]. + +Social History: +No changes since last admission: +He lives with his wife and 6 year old son. [**Name (NI) **] works as a sales +manager for [**Company 56968**], although he has been out of work +recently due to his recent hospitalizations. He does not smoke +and has not had any alcohol intake since prior to transplant. + + +Family History: +No changes since last admission: +His paternal grandmother had breast cancer and a paternal uncle +had cancer of an unknown etiology. His father had diabetes and +died of a myocardial infarction. + +Physical Exam: +Vitals: T 103.1 P 165 R 25 127/70 100% on 2L +General: Chronically ill appearing male, appearing older than +stated age. Dry, flaking skin over sclap. Appears in moderate +distress but speaking in full sentences. +HEENT: NC/AT. Dry flaking skin, alopecia. Oropharynx clear +without any evidence of thrush, moist mucous membranes, no +exudates or lesions. +Neck: Leathery skin, no apparent LAD. +Lungs: CTAB, no w/r/r, good air movement. +Cardiac: Tachycardic, regular, S1, S2, no m/g/r. +Abdomen: Soft, non-tender, non-distended, +BS, difficult to +assess for HSM due to thickened skin. +Skin: Scleroderma-like changes, thickened skin. Areas of hypo +and hyperpigmentation over face, back, arms, abdomen. On left +side, PICC dressing is in place. PICC site c/d/i without +erythema/tenderness/induration. +Neuro: A&Ox3, CNs sym and intact. + + +Pertinent Results: +[**2170-4-6**] 11:50AM WBC-12.6* RBC-3.94* HGB-11.4* HCT-36.7* +MCV-93 MCH-28.8 MCHC-31.0 RDW-25.4* +[**2170-4-6**] 11:50AM PLT SMR-HIGH PLT COUNT-462* +[**2170-4-6**] 11:50AM NEUTS-86.3* BANDS-0 LYMPHS-9.3* MONOS-3.9 +EOS-0.4 BASOS-0.1 +[**2170-4-6**] 11:50AM GRAN CT-[**Numeric Identifier 56969**]* +[**2170-4-6**] 11:50AM GLUCOSE-121* UREA N-19 CREAT-0.5 SODIUM-134 +POTASSIUM-4.5 CHLORIDE-94* TOTAL CO2-30 ANION GAP-15 +. +CTA Chest ([**2170-4-7**]) +1. New right lower lobe consolidation consistent with acute +pneumonia. +2. Multiple nodular opacities in the right and left upper lobes +are grossly unchanged. Stable small left pleural effusion. +. +CT Chest ([**2170-4-14**]) +1. Marked interval increase in the large left pleural effusion +with +associated compressive left lower lobe atelectasis. An embedded +focus of +consolidation with a parapneumonic effusion cannot be excluded. +2. Small focus of tree-in-[**Male First Name (un) 239**] opacity at superolateral right +middle lobe +(2:24) may reflect evolving infection/inflammation. +3. Interval improvement in the right lower lobe atelectasis with +better +parenchymal aeration of the right lung. Multiple bilateral +pulmonary nodules are unchanged since [**2170-4-7**]. +. +Echo ([**2170-4-17**]) +The left atrium is normal in size. Left ventricular wall +thicknesses and cavity size are normal. There is mild global +left ventricular hypokinesis (LVEF = 45-50 %). Overall left +ventricular systolic function is mildly depressed. Tissue +Doppler imaging suggests a normal left ventricular filling +pressure (PCWP<12mmHg). Right ventricular chamber size and free +wall motion are normal. The aortic valve leaflets appear +structurally normal with good leaflet excursion. No aortic +regurgitation is seen. The mitral valve leaflets are mildly +thickened. No mitral regurgitation is seen. The pulmonary artery +systolic pressure could not be determined. There is no +pericardial effusion. +IMPRESSION: Suboptimal image quality. Mild global left +ventricular systolic dysfunction with normal estimated left +ventricular filling pressure. Tachycardia. Compared with the +prior study (images reviewed) of [**2170-3-15**], the heart rate is +faster. The other findings are similar. + +Brief Hospital Course: +Patient presented to outpatient clinic with hypotension and +tachycardia. Attempted stabilization on floor, but then +admitted to the ICU for management. +. +#Pneumosepsis: Patient admitted to the ICU for management. +Impression on admission was for sepsis. Patient was +aggressively volume resuscitated with improvement in his BP and +HR. Started on cefepime and caspofungin on arrival. Central +venous access was attempted w/o success. Left IJ repeatedly +coiled and turned upwards into R-IJ on CXR. Line was d/c'd and +decision was made to use PICC line in interim period. Blood +cultures grew strep pneumo pan sensitive and patient was +narrowed to nafcillin but then later changed to ceftriaxone +given its improved activity against strep infections. CT of the +chest confirmed lobar infiltrate in RLL w/o evidence of +significant effusion. Patient became mildly hypoxic following +rehydration requiring at peak time 4L NC. Subsequently +respiratory status improved to 2L at time of call out from ICU, +but still desating with exertion. CXR demonstrated minimal +pleural effusion on right at site of infiltrate and moderate +L-pleural effusion thought to be related to fluids. A repeat +chest CT was obtained which confirmed the presence of a large +left effusion; the pulmonary service was consulted and a +thoracentesis was performed though only a few cc's of fluid were +able to be aspirated. Fluid analysis demonstrated an exudate +that had no micro growth at the time of discharge. The pt +developed a small PTX as a result of the thoracentesis however +he was asymptomatic with this and it improved with supportive +care. At the time of discharge, the pt was completing his two +week course of ceftriaxone. +. +#GVHD: The pt's GVHD is severe. He was continued on his home +regimen which includes prednisone, tacrolimus, CellCept and +Gleevec. His tacrolimus dosing was uptitrated based on his serum +levels. Prophylaxis with Bactrim, acyclovir, and posaconazole +was continued. +. +#Hypertension: The pt's metoprolol was held on arrival to ICU. +It was restarted at 1/2 home dose prior to call out from the +MICU and eventually titrated up to above his admission dose to +better treat his tacycardia. +. +#Tachycardia: The pt's baseline HR is known to be in 100-120's. +This has been attributed in the past to chemotherapy, radiation, +or GVHD. On this admission, the pt's metoprolol was titrated up +for better HR control with excellent effect. +. +#H/O PE: The pt has a history of PE in the past. A CTA at time +of admission was negative for additional PE. His home Lovenox +was continued. + +Medications on Admission: +1. Acyclovir 200 mg/5 mL Suspension [**Year (4 digits) **]: Ten (10) mL PO every +eight (8) hours. +2. Cyclobenzaprine 10 mg Tablet [**Year (4 digits) **]: One (1) Tablet PO BID (2 +times a day) as needed. +3. Imatinib 400 mg Tablet [**Year (4 digits) **]: One (1) Tablet PO DAILY (Daily). + +4. Enoxaparin 60 mg/0.6 mL Syringe [**Year (4 digits) **]: Sixty (60) mg +Subcutaneous Q12H (every 12 hours). +5. Fluticasone 110 mcg/Actuation Aerosol [**Year (4 digits) **]: Two (2) Puff +Inhalation [**Hospital1 **] (2 times a day). +6. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] once a day. +7. Lorazepam 0.5 mg Tablet [**Last Name (STitle) **]: 1-2 Tablets PO every six (6) +hours as needed for nausea, anxiety. +8. Metoprolol Tartrate 25 mg Tablet [**Last Name (STitle) **]: Two (2) Tablet PO TID +(3 times a day). +9. Mycophenolate Mofetil 200 mg/mL Suspension for Reconstitution +[**Last Name (STitle) **]: Seven [**Age over 90 1230**]y (750) mg PO BID (2 times a day). +10. Posaconazole 200 mg/5 mL Suspension [**Age over 90 **]: Two Hundred (200) +mg PO three times a day. +11. Tacrolimus 0.5 mg Capsule [**Age over 90 **]: One (1) Capsule PO QAM (once +a day (in the morning)). +12. Prednisone 5 mg/mL Concentrate [**Age over 90 **]: Fifteen (15) mg PO twice +a day. +13. Artificial Saliva 0.15-0.15 % Solution [**Age over 90 **]: Thirty (30) ML +Mucous membrane QID (4 times a day) as needed. +14. Trimethoprim-Sulfamethoxazole 40-200 mg/5 mL Suspension [**Age over 90 **]: +Ten (10) ML PO DAILY (Daily). +15. Sarna Anti-Itch 0.5-0.5 % Lotion Topical +16. Insulin Regular Human 100 unit/mL Solution [**Age over 90 **]: sliding +scale Injection ASDIR (AS DIRECTED). +17. Ceftriaxone-Dextrose (Iso-osm) 1 gram/50 mL Piggyback [**Age over 90 **]: +One (1) gram Intravenous Q24H (every 24 hours): Day 1 = [**2170-4-14**]. +Please continue through [**2170-4-28**]. +18. Artificial Tears Ophthalmic + +Discharge Medications: +1. Acyclovir 200 mg/5 mL Suspension [**Month/Day/Year **]: Ten (10) mL PO every +eight (8) hours. +2. Cyclobenzaprine 10 mg Tablet [**Month/Day/Year **]: One (1) Tablet PO BID (2 +times a day) as needed. +3. Imatinib 400 mg Tablet [**Month/Day/Year **]: One (1) Tablet PO DAILY (Daily). + +4. Enoxaparin 60 mg/0.6 mL Syringe [**Month/Day/Year **]: Sixty (60) mg +Subcutaneous Q12H (every 12 hours). +5. Fluticasone 110 mcg/Actuation Aerosol [**Month/Day/Year **]: Two (2) Puff +Inhalation [**Hospital1 **] (2 times a day). +6. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] once a day. +7. Lorazepam 0.5 mg Tablet [**Last Name (STitle) **]: 1-2 Tablets PO every six (6) +hours as needed for nausea, anxiety. +8. Metoprolol Tartrate 25 mg Tablet [**Last Name (STitle) **]: Three (3) Tablet PO TID +(3 times a day). +9. Mycophenolate Mofetil 200 mg/mL Suspension for Reconstitution +[**Last Name (STitle) **]: Seven [**Age over 90 1230**]y (750) mg PO BID (2 times a day). +10. Posaconazole 200 mg/5 mL Suspension [**Age over 90 **]: Two Hundred (200) +mg PO three times a day. +11. Tacrolimus 1 mg Capsule [**Age over 90 **]: One (1) Capsule PO QAM (once a +day (in the morning)). +12. Prednisone 5 mg/mL Concentrate [**Age over 90 **]: Fifteen (15) mg PO twice +a day. +13. Artificial Saliva 0.15-0.15 % Solution [**Age over 90 **]: Thirty (30) ML +Mucous membrane QID (4 times a day) as needed. +14. Trimethoprim-Sulfamethoxazole 40-200 mg/5 mL Suspension [**Age over 90 **]: +Ten (10) ML PO DAILY (Daily). +15. Sarna Anti-Itch 0.5-0.5 % Lotion Topical +16. Insulin Regular Human 100 unit/mL Solution [**Age over 90 **]: sliding +scale Injection ASDIR (AS DIRECTED). +17. Ceftriaxone-Dextrose (Iso-osm) 1 gram/50 mL Piggyback [**Age over 90 **]: +One (1) gram Intravenous Q24H (every 24 hours): Day 1 = [**2170-4-14**]. +Please continue through [**2170-4-28**]. +18. Artificial Tears Ophthalmic + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +pneumosepsis +large B cell lymphoma +GVHD +cardiomyopathy +tachycardia + + +Discharge Condition: +Overall improved. Vitals stable, afebrile. + + +Discharge Instructions: +You were admitted with pneumonia and low blood pressure. We have +treated you and you have improved. You are now being discharged +to rehab for further care. +. +Please contact Dr. [**Last Name (STitle) 410**], the on-call hematology/oncology +fellow, or go to the emergency if you experience any fevers +above 100.0, chills, significant nausea or vomiting, inability +to keep down food or drink, difficulty breathing, cough, chest +pain, or other concerning symptoms. + +Followup Instructions: +You have a follow-up appointment scheduled with Dr. [**Last Name (STitle) 410**] on +[**Last Name (LF) 2974**], [**4-27**] at 9:00AM. Please call ([**Telephone/Fax (1) 14703**] if you +need to change this. +. +You have a follow-up appointment scheduled with Drs. [**First Name (STitle) **] and +[**Name5 (PTitle) **] from the [**Hospital1 18**] Pulmonary Division on [**5-21**] at +2:40PM. Please call [**Telephone/Fax (1) 612**] if you need to change this. + + + +",109,2170-04-07 12:33:00,2170-04-20 12:43:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,REHAB/DISTINCT PART HOSP,FEVER/SHORTNESS OF BREATH," +patient presented to outpatient clinic with hypotension and +tachycardia. attempted stabilization on floor, but then +admitted to the icu for management. +. +#pneumosepsis: patient admitted to the icu for management. +impression on admission was for sepsis. patient was +aggressively volume resuscitated with improvement in his bp and +hr. started on cefepime and caspofungin on arrival. central +venous access was attempted w/o success. left ij repeatedly +coiled and turned upwards into r-ij on cxr. line was d/cd and +decision was made to use picc line in interim period. blood +cultures grew strep pneumo pan sensitive and patient was +narrowed to nafcillin but then later changed to ceftriaxone +given its improved activity against strep infections. ct of the +chest confirmed lobar infiltrate in rll w/o evidence of +significant effusion. patient became mildly hypoxic following +rehydration requiring at peak time 4l nc. subsequently +respiratory status improved to 2l at time of call out from icu, +but still desating with exertion. cxr demonstrated minimal +pleural effusion on right at site of infiltrate and moderate +l-pleural effusion thought to be related to fluids. a repeat +chest ct was obtained which confirmed the presence of a large +left effusion; the pulmonary service was consulted and a +thoracentesis was performed though only a few ccs of fluid were +able to be aspirated. fluid analysis demonstrated an exudate +that had no micro growth at the time of discharge. the pt +developed a small ptx as a result of the thoracentesis however +he was asymptomatic with this and it improved with supportive +care. at the time of discharge, the pt was completing his two +week course of ceftriaxone. +. +#gvhd: the pts gvhd is severe. he was continued on his home +regimen which includes prednisone, tacrolimus, cellcept and +gleevec. his tacrolimus dosing was uptitrated based on his serum +levels. prophylaxis with bactrim, acyclovir, and posaconazole +was continued. +. +#hypertension: the pts metoprolol was held on arrival to icu. +it was restarted at 1/2 home dose prior to call out from the +micu and eventually titrated up to above his admission dose to +better treat his tacycardia. +. +#tachycardia: the pts baseline hr is known to be in 100-120s. +this has been attributed in the past to chemotherapy, radiation, +or gvhd. on this admission, the pts metoprolol was titrated up +for better hr control with excellent effect. +. +#h/o pe: the pt has a history of pe in the past. a cta at time +of admission was negative for additional pe. his home lovenox +was continued. + + ","PRIMARY: [Pneumococcal septicemia [Streptococcus pneumoniae septicemia]] +SECONDARY: [Pneumococcal pneumonia [Streptococcus pneumoniae pneumonia]; Septic shock; Unspecified pleural effusion; Iatrogenic pneumothorax; Complications of transplanted bone marrow; Other primary cardiomyopathies; Hyposmolality and/or hyponatremia; Severe sepsis; Unspecified essential hypertension]" +28999,128539.0,16343,2179-03-03,16341,118414.0,2178-11-10,Discharge summary,"Admission Date: [**2178-11-2**] Discharge Date: [**2178-11-10**] + +Date of Birth: [**2116-7-30**] Sex: M + +Service: NEUROSURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1854**] +Chief Complaint: +CC:[**CC Contact Info 46547**] + +Major Surgical or Invasive Procedure: +VP shunt placement + + +History of Present Illness: +HPI: +Pt unreliable historian secondary to confusion. 62yo male with +known hx of clear cell renal cancer with brain metastases. [**Name (NI) 1094**] +wife reports 5day hx of increased confusion, unstable wide +shuffled gait, blurred vision not improved with new glasses. + + +Past Medical History: +PMHx: +-clear cell renal cancer/brain metastases +-[**2173-12-4**] right radical nephrectomy and wedge resection of the + + right lower lung. +-Tarceva/Avastin trial [**7-/2175**] till [**2177-5-7**] when started Avastin +alone. +-Increasing lung nodules [**2177-12-10**] and screening for IL-2 revealed + +brain met. +-Received one cycle of IL-2. +He is s/p: +1. Cyberknife SRS [**Date range (1) 46548**] to 2750 cGy brainstem +2. Cyberknife SRS [**2178-5-5**] to 1800 cGy left cerebellar met +3. WBXRT [**Date range (1) 46549**]/07 to 3600 cGy +4. Sutent started [**2178-7-7**] + + +Social History: +Social Hx: lives with his wife + + +Family History: +nc + +Physical Exam: +PHYSICAL EXAM: +T: 97.3 BP: 106/60 HR:63 R: 16 O2Sats: 97% RA +Gen: WD/WN, comfortable, NAD. +HEENT: Radiation induced alopecia. Pupils: [**2-6**], sluggish rxn +EOMs: intact with FFOV +Neck: Supple. +Lungs: CTA bilaterally. +Cardiac: RRR. nl S1/S2. +Abd: Soft, NT, BS+ +Extrem: Warm and well-perfused. +Neuro: +Mental status: Awake and alert, cooperative with exam, flat +affect able to follow commands. +Orientation: Oriented to person, place, not time. +Language: Speech slow, deliberate. Slow to process, able to +repeat. +Naming intact. No dysarthria or paraphasic errors. + +Cranial Nerves: +I: Not tested +II: Pupils equally round and reactive to light, 3-2mm +bilaterally. Visual fields are full to confrontation. +III, IV, VI: Extraocular movements intact bilaterally without +nystagmus. +V, VII: Facial strength and sensation intact and symmetric. +VIII: Hearing intact to voice. +IX, X: Palatal elevation symmetrical. +[**Doctor First Name 81**]: Sternocleidomastoid and trapezius normal bilaterally. +XII: Tongue midline without fasciculations. + +Motor: Normal bulk and tone bilaterally. No abnormal movements. +Strength full power [**4-11**] throughout. No pronator drift + +Sensation: Intact to light touch +Toes downgoing bilaterally + +Coordination: decreased finger to nose coordination on Rt, rapid +alternating movements, heel to shin + +on discharge his orientation, speech, fluency of speech and gait +have improved. + +Pertinent Results: +CT: +Interval increase in size of the metastatic lesion involving the + +right tectum which now measures 17 x 18 mm with a hyperdense +appearance concerning for hemorrhage. There is interval +increase +in associated midbrain edema as well as mass effect on the +aquaduct of sylvius. There is resultant hydrocephalus, new, with +increase in periventricular hypoattenuation compatible with +transependymal flow of CSF in the setting of hydrocephalus. +There is a stable appearance of the small lesion in the +eriventricular white matter adjacent to the right occipital +[**Doctor Last Name 534**]. +The lesion previously noted in the left CP angle is poorly +assessed. There is no evidence of major vascular territorial +infarction. There is no extra-axial hemorrhage. Surrounding soft + +tissue and osseous structures appear unremarkable. Nodular +mucosal thickening noted in the maxillary sinuses bilaterally. +Right mastoid air cell opacification is noted. + +[**2178-11-2**] 01:15PM WBC-4.8 RBC-3.31* HGB-12.4* HCT-38.5* +MCV-116*# MCH-37.3* MCHC-32.2 RDW-15.3 +[**2178-11-2**] 01:15PM GLUCOSE-92 UREA N-27* CREAT-1.6* SODIUM-141 +POTASSIUM-5.8* CHLORIDE-108 TOTAL CO2-19* ANION GAP-20 + +Brief Hospital Course: +The patient is a 62 year-old male who presented with tactile +tumor and renal cell carcinoma and hydrocephalus. On [**2178-11-4**] he +underwent a VP shunt successfully, and he was taken back to the +recovery room, extubated and was noted to be neurologically +improved from his preoperative condition. Post-op CT stable. +On [**2178-11-5**] in am he was lethargic, stat head CT was repeated, +which was stable. Prior to CT blood glucose was checked, which +was decreased, and he received D50 [**12-9**] an ampule with elevated +blood glucose when rechecked in 30 min. +The rest of his hospitalization was uneventful. he advanced in +his diet and activity. He was seen by PT and OT and deemed a +candidate for rehab. he is voiding freely and moving his +bowels. We contact[**Name (NI) **] Dr. [**Last Name (STitle) **] about his sutent and megace in +the peri-operative phase. He stated it was best to start him on +wednesday (one week post op). His follow up appts are detailed +in the discharge instructions. + +Medications on Admission: +Medications prior to admission: +Atenolol 50 mg PM, Lisinopril 20 mg PM, Zocor 20 mg +PM, Provigil 400 mg AM, Zyprexa 2.5 mg PRN, Pepcid 10 mg PRN, +Megestrol 2 tsp (400 mg) when on Sutent, Sutent 25 mg (2 weeks +on/1 week off). + + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +2. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily). +3. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +4. Famotidine 20 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +5. Lisinopril 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Atenolol 50 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +7. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +8. Modafinil 100 mg Tablet Sig: Four (4) Tablet PO daily (). +9. Olanzapine 2.5 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day) as needed. +10. Megestrol 40 mg/mL Suspension Sig: One (1) PO DAILY +(Daily). +11. Oxycodone-Acetaminophen 5-325 mg Tablet Sig: 1-2 Tablets PO +Q4H (every 4 hours) as needed: PLEASE DO NOT EXCEED MORE THAN +4000 MG OF TYLENOL OVER 24 HOUR PERIOD. +12. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +13. Magnesium Hydroxide 400 mg/5 mL Suspension Sig: Thirty (30) +ML PO Q6H (every 6 hours) as needed. +14. Insulin Regular Human 100 unit/mL Solution Sig: One (1) +Injection ASDIR (AS DIRECTED): PLEASE FOLLOW SLIDING SCALE. +15. Dexamethasone 1 mg Tablet Sig: Three (3) Tablet PO tid () +for 3 doses. +16. Dexamethasone 1 mg Tablet Sig: Two (2) Tablet PO TID (3 +times a day) for 3 doses. +17. Dexamethasone 1 mg Tablet Sig: One (1) Tablet PO tid () for +3 doses. +18. Dexamethasone 1 mg Tablet Sig: One (1) Tablet PO bid () for +2 doses. +19. Dexamethasone 1 mg Tablet Sig: One (1) Tablet PO qd () for 1 +doses. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital **] Medical Center - [**Hospital1 3597**] + +Discharge Diagnosis: +OBSTRUCTIVE HYDROCEPHALUS + + +Discharge Condition: +NEUROLOGICALLY STABLE + + +Discharge Instructions: +DISCHARGE INSTRUCTIONS FOR CRANIOTOMY/HEAD INJURY + +?????? Have your incision checked daily for signs of infection +?????? Take your pain medicine as prescribed +?????? Exercise should be limited to walking; no lifting, straining, +excessive bending +?????? You may wash your hair only after sutures and/or staples have +been removed +?????? You may shower before this time with assistance and use of a +shower cap +?????? Increase your intake of fluids and fiber as pain medicine +(narcotics) can cause constipation +?????? Unless directed by your doctor, do not take any +anti-inflammatory medicines such as Motrin, aspirin, Advil, +Ibuprofen etc. +?????? Clearance to drive and return to work will be addressed at +your post-operative office visit + +CALL YOUR SURGEON IMMEDIATELY IF YOU EXPERIENCE ANY OF THE +FOLLOWING: + +?????? New onset of tremors or seizures +?????? Any confusion or change in mental status +?????? Any numbness, tingling, weakness in your extremities +?????? Pain or headache that is continually increasing or not +relieved by pain medication +?????? Any signs of infection at the wound site: redness, swelling, +tenderness, drainage +?????? Fever greater than or equal to 101?????? F + +Followup Instructions: +PLEASE HAVE YOUR SUTURES REMOVED ON [**2178-11-18**] BY A REHAB HEALTH +CARE PROVIDER + +PLEASE CALL [**Telephone/Fax (1) **] TO SCHEDULE AN APPOINTMENT WITH DR. +[**Last Name (STitle) **] TO BE SEEN IN FOUR WEEKS. + +YOU WILL NEED AN [**Last Name (STitle) 4338**] OF THE BRAIN WITH and WITHOUT GADOLIDIUM + +Provider: [**Name10 (NameIs) 5005**] [**Last Name (NamePattern4) 5342**], MD Phone:[**Telephone/Fax (1) 44**] +Date/Time:[**2178-12-14**] 3:00 +Provider: [**Name10 (NameIs) 4338**] Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2178-12-14**] 12:20 +F/U with Dr. [**Last Name (STitle) **] in [**1-10**] weeks, please call [**Telephone/Fax (1) 38171**] + + + +Completed by:[**2178-11-10**]",113,2178-11-02 17:33:00,2178-11-10 17:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,REHAB/DISTINCT PART HOSP,ALTERED MENTAL STATUS," +the patient is a 62 year-old male who presented with tactile +tumor and renal cell carcinoma and hydrocephalus. on [**2178-11-4**] he +underwent a vp shunt successfully, and he was taken back to the +recovery room, extubated and was noted to be neurologically +improved from his preoperative condition. post-op ct stable. +on [**2178-11-5**] in am he was lethargic, stat head ct was repeated, +which was stable. prior to ct blood glucose was checked, which +was decreased, and he received d50 [**12-9**] an ampule with elevated +blood glucose when rechecked in 30 min. +the rest of his hospitalization was uneventful. he advanced in +his diet and activity. he was seen by pt and ot and deemed a +candidate for rehab. he is voiding freely and moving his +bowels. we contact[**name (ni) **] dr. [**last name (stitle) **] about his sutent and megace in +the peri-operative phase. he stated it was best to start him on +wednesday (one week post op). his follow up appts are detailed +in the discharge instructions. + + ","PRIMARY: [Obstructive hydrocephalus] +SECONDARY: [Secondary malignant neoplasm of brain and spinal cord; Other specified visual disturbances; Unspecified sleep apnea; Personal history of malignant neoplasm of renal pelvis; Personal history of irradiation, presenting hazards to health]" +29035,152710.0,17989,2154-02-11,17959,124081.0,2153-10-03,Discharge summary,"Admission Date: [**2153-10-1**] [**Month/Day/Year **] Date: [**2153-10-3**] + +Date of Birth: [**2089-12-13**] Sex: F + +Service: SURGERY + +Allergies: +Erythromycin Base / Indomethacin / Actonel / Reglan + +Attending:[**First Name3 (LF) 695**] +Chief Complaint: +Dyspnea + +Major Surgical or Invasive Procedure: +[**2153-10-2**]: Thoracentesis + +History of Present Illness: +63F 2 months s/p combined kidney and liver [**Month/Day/Year **] and +splenectomy ([**2153-7-22**]) for end-stage liver disease +secondary to nonalcoholic steatohepatitis and end-stage renal +disease. She is currently at a [**Hospital1 1501**] for rehab and wound care. +Also c/o chronic abdominal pain. Recent admission for UTI - on +meropenum. Also with an open wound being packed W-Dry. Now c/o +SOB and low grade fever (100.4). No CP. Says he Q. +Minimal pain at kidney incision. + + + +Past Medical History: +- NASH cirrhosis: Liver bx [**2152-9-6**] = Stage IV cirrhosis, Grade 2 + +inflammation, complicated by portal HTN +- Esophageal varicies (grade I and II, s/p banding), s/p TIPS +[**8-15**] +- History of encephalopathy +- History of ascites +- Anemia +- Thrombocytopenia +- ESRD on HD due to diabetes and contrast-induced nephropathy +- Type 2 diabetes with retinopathy, nephropathy, and neuropathy + +- History of C. difficile infection +- History of seizures +- Small left frontal meningioma +- Hypertension +- GERD +- OSA +- Leg cramps/? RLS +- DJD of neck +- History of dermoid cyst +- Right adrenal mass +-[**2153-9-22**] klebsiella uti +. +Past Surgical History: (per OMR) +- Status post cholecystectomy followed by tubal ligation +- Status post left oopherectomy +- Status post appendectomy +. +Past Psychiatric History: (per OMR) +Depression first experienced in high school. First +hospitalization in [**2131**] (after husband's death). History of +cutting and burning self. History of overdose. One course of ECT +in past that was helpful. +. + +Social History: +Widowed, lived in [**Hospital3 **] although most recently has +been at [**Hospital1 2670**] SNIF. Has 4 children, several in MA. Smoking: +None; EtOH: Never; Illicits: None + + +Family History: +Mom: CAD, stroke +Dad: HTN, DM + +Physical Exam: +100.4 86 120/62 18 84% RA in triage +AAOx3 NAD no icterus or jaundice +RRR +decreased BS on R side, left clear +Liver scar well healed, lower abd wound with wet to dry - +granulating well +tender R side of abd wound to mild palpation +No diffuse guarding or rebound +mild edema, extrem warm + + +Pertinent Results: +On Admisssion: [**2153-10-1**] +WBC-3.3* RBC-3.10* Hgb-9.7* Hct-30.4* MCV-98 MCH-31.3 MCHC-31.8 +RDW-18.3* Plt Ct-456* +PT-12.3 PTT-28.3 INR(PT)-1.0 +Glucose-82 UreaN-17 Creat-0.7 Na-139 K-4.7 Cl-103 HCO3-27 +AnGap-14 +ALT-21 AST-23 CK(CPK)-24* AlkPhos-109 TotBili-0.3 +At [**Month/Day/Year **] [**2153-10-3**] +WBC-3.0* RBC-2.86* Hgb-9.1* Hct-28.3* MCV-99* MCH-31.7 MCHC-32.1 +RDW-18.3* Plt Ct-417 +Glucose-127* UreaN-21* Creat-0.9 Na-143 K-4.4 Cl-106 HCO3-27 +AnGap-14 +ALT-18 AST-14 AlkPhos-102 TotBili-0.2 +Calcium-8.6 Phos-4.7* Mg-1.8 + +Brief Hospital Course: +63 y/o female s/p liver/kidney [**Month/Day/Year **] who returns with +ongoing issues of vague abdominal pain and also some dyspnea. +She has had a recent admission for a UTI being treated with +Meropenum through [**10-6**]. +She presented with low grade fever and dyspnea and was +de-satting into the high 80's. A non-rebreather was placed, this +type of face mask causes great anxiety for this patient. +A chest x-ray shows Right pleural effusion with basilar +atelectasis, cannot exclude +pneumonia and an ABG confirmed respiratory acidosis. +On [**10-2**] she underwent a thoracentesis and [**2144**] cc clear straw +colored drainage was removed by the interventional pulmonology +team. Her O2 requirement immediately dropped and her respiratory +rate improved and she felt subjectively better. +In addition she received IV lasix with good resulting urine +output. +The patient was transferred to the regular surgical floor and +continued to feel subjectively better with decreasing O2 +requirements, and by post procedure day one she was on room air +with no evidence of desats and routinely 94% on room air. +The patient also had c/o right calf pain, and the right lower +extremity is larger than the left. Non-invasive studies reveal +no evidence of DVT. +Foley was discontinued and the patient c/o urinary discomfort. +She will be treated with pyridium as the UA is negative and she +continues on the meropenum. +Chest xray on [**10-3**] shows improvement. The left side is more +clear, the right side shows small to moderate pleural effusion. +The vasculature is engorged but does not show pulmonary edema. +She continues to atelectasis on the right. Physical exam reveals +no crackles but there is diminished breath sounds about midway +up lung field. +The interventional pulmonary team was contact[**Name (NI) **] for further +recommendations and she is to be treated symptomatically PRN. +The lasix dose was increased while she was hospitalized. + + +Medications on Admission: +Furosemide 20' +Amlodipine 5' +Prednisone 5' +citalopram 60' +Levetiracetam 500"" +MMF 250"" +Nystatin 5"""" +Omeprazole 20' +Trimethoprim-Sulfamethoxazole 80-400' +Valganciclovir 450' +Senna 1"" +Docusate Sodium 100"" +Lidocaine 5 %(700 mg/patch) +Tacrolimus 3"" +Meropenem 500"""" +Trazodone 50' +Insulin NPH 30' + + +[**Name (NI) **] Medications: +1. Insulin NPH Human Recomb 100 unit/mL Suspension Sig: Thirty +(30) units Subcutaneous once a day. +2. Insulin Lispro 100 unit/mL Solution Sig: per sliding scale +Subcutaneous four times a day. +3. Valganciclovir 450 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Trimethoprim-Sulfamethoxazole 80-400 mg Tablet Sig: One (1) +Tablet PO DAILY (Daily). +5. Amlodipine 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Citalopram 20 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +7. Mycophenolate Mofetil 250 mg Capsule Sig: One (1) Capsule PO +BID (2 times a day). +8. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO DAILY (Daily). +9. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +10. Docusate Sodium 100 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +11. Nystatin 100,000 unit/mL Suspension Sig: Five (5) ml PO four +times a day. +12. Trazodone 50 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +13. Levetiracetam 500 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +14. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain: 6 tablets maximum daily. +15. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +16. Prednisone 2.5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +17. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +18. Tacrolimus 1 mg Capsule Sig: Three (3) Capsule PO twice a +day. +19. Lorazepam 0.5 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime) as needed for anxiety. +20. Phenazopyridine 100 mg Tablet Sig: One (1) Tablet PO TID (3 +times a day) for 3 days. +21. Meropenem 500 mg Recon Soln Sig: One (1) Recon Soln +Intravenous Q6H (every 6 hours) for 4 days: Through [**2153-10-6**]. +22. Heparin, Porcine (PF) 10 unit/mL Syringe Sig: per protocol +ML Intravenous PRN (as needed) as needed for line flush. + + +[**Month/Day/Year **] Disposition: +Extended Care + +Facility: +[**Hospital 2670**] Rehab + +[**Hospital **] Diagnosis: +Pleural effusion; s/p thoracentesis + + +[**Hospital **] Condition: +Stable/ Good. No O2 requirement + + +[**Hospital **] Instructions: +Please call the [**Hospital **] clinic at [**Telephone/Fax (1) 673**] for fever > +101, chills, nausea, vomiting, diarrhea, chest pain, increased +shortness of breath, increased abdominal pain or other +concerning symptoms +Continue labwork evry Monday and Thursday and fax to +[**Telephone/Fax (1) 697**] to include CBC, Chem 10, LFTs, UA, trough Prograf +The [**Telephone/Fax (1) **] clinic will work with the facility for medication +management. Please do not change any immunosuppressives with +checking with [**Telephone/Fax (1) **] clinic +No heavy lifting +Patient may shower, replace dressing. +Complete Meropenum course on [**2153-10-6**] + +Followup Instructions: +[**Name6 (MD) 2105**] [**Name8 (MD) 2106**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2153-10-26**] +11:00 +[**First Name8 (NamePattern2) 161**] [**Name6 (MD) 162**] [**Name8 (MD) 163**], MD Phone:[**Telephone/Fax (1) 921**] Date/Time:[**2153-10-29**] 8:30 + + + [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 707**] MD, [**MD Number(3) 709**] + +Completed by:[**2153-10-3**]",131,2153-10-01 18:57:00,2153-10-03 14:20:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,"FEVER,ORIGIN UNKNOWN"," +63 y/o female s/p liver/kidney [**month/day/year **] who returns with +ongoing issues of vague abdominal pain and also some dyspnea. +she has had a recent admission for a uti being treated with +meropenum through [**10-6**]. +she presented with low grade fever and dyspnea and was +de-satting into the high 80s. a non-rebreather was placed, this +type of face mask causes great anxiety for this patient. +a chest x-ray shows right pleural effusion with basilar +atelectasis, cannot exclude +pneumonia and an abg confirmed respiratory acidosis. +on [**10-2**] she underwent a thoracentesis and [**2144**] cc clear straw +colored drainage was removed by the interventional pulmonology +team. her o2 requirement immediately dropped and her respiratory +rate improved and she felt subjectively better. +in addition she received iv lasix with good resulting urine +output. +the patient was transferred to the regular surgical floor and +continued to feel subjectively better with decreasing o2 +requirements, and by post procedure day one she was on room air +with no evidence of desats and routinely 94% on room air. +the patient also had c/o right calf pain, and the right lower +extremity is larger than the left. non-invasive studies reveal +no evidence of dvt. +foley was discontinued and the patient c/o urinary discomfort. +she will be treated with pyridium as the ua is negative and she +continues on the meropenum. +chest xray on [**10-3**] shows improvement. the left side is more +clear, the right side shows small to moderate pleural effusion. +the vasculature is engorged but does not show pulmonary edema. +she continues to atelectasis on the right. physical exam reveals +no crackles but there is diminished breath sounds about midway +up lung field. +the interventional pulmonary team was contact[**name (ni) **] for further +recommendations and she is to be treated symptomatically prn. +the lasix dose was increased while she was hospitalized. + + + ","PRIMARY: [Unspecified pleural effusion] +SECONDARY: [Acidosis; Urinary tract infection, site not specified; Kidney replaced by transplant; Liver replaced by transplant; Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled; Background diabetic retinopathy; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Epilepsy, unspecified, without mention of intractable epilepsy; Unspecified essential hypertension; Esophageal reflux; Obstructive sleep apnea (adult)(pediatric)]" +29035,152710.0,17989,2154-02-11,17958,108831.0,2153-08-21,Discharge summary,"Admission Date: [**2153-7-9**] [**Month/Day/Year **] Date: [**2153-8-21**] + +Date of Birth: [**2089-12-13**] Sex: F + +Service: SURGERY + +Allergies: +Erythromycin Base / Indomethacin / Actonel / Reglan + +Attending:[**First Name3 (LF) 695**] +Chief Complaint: +GI bleeding. + +Major Surgical or Invasive Procedure: +[**2153-7-22**]: liver and kidney [**Month/Day/Year **] + +History of Present Illness: +The patient is a 63 year old female iwth a history of NASH +cirrhosis awaiting [**Month/Day/Year **], complicated by portal vein +hypertension, grade 2 esophogeal varices s/p TIPS, +encephalopathy, recurrent pleural effusions, ESRD on HD awaiting +[**Month/Day/Year **] was was transfered from [**Hospital1 **] Care with GIB +unresponsive to multiple transfusions. The patient was recently +hospitalized at [**Hospital1 18**] from [**Date range (1) 19159**] for altered mental status +believed secondary to hepatic encephalopathy. During the +admission the patient had a large melanotic stool, and an EGD +showed which showed portal hypertensive gastropathy vs. GAVE +syndrome without varices. On day of [**Date range (1) **], the patient had +a hct of 26.9. While at [**Hospital1 **], patient describes having +melena for a couple of days, without BRBPR. She reportedly +received 4units of PRBC over the weekend, without improvement of +HCT. When checked at [**Hospital1 **], hct was less than 21, and she was +transfered to [**Hospital1 18**] for further evaluation. Of note, the +patient has questioning of clotting of her AV graft, with an +inability to dialyze on the day of presentation. +. +On presenation ot [**Hospital1 18**], initial vitas were 98.5, BP 102/39, HR +56, 94% on RA. Her vitals remained stable, and hct was 23.3. +She was transfused with 1 unit of PRBC, cipro for SBP ppx, IV +protonix, started on an octreotide gtt, and given 1 L of NS. +She was noted to have a melanotic, guaic positive stool. She +was admitted to the MICU for further manegment. +. + + +Past Medical History: +- NASH cirrhosis: Liver bx [**2152-9-6**] = Stage IV cirrhosis, Grade 2 + +inflammation, complicated by portal HTN +- Esophageal varicies (grade I and II, s/p banding), s/p TIPS +[**8-15**] +- History of encephalopathy +- History of ascites +- Anemia +- Thrombocytopenia +- ESRD on HD due to diabetes and contrast-induced nephropathy +- Type 2 diabetes with retinopathy, nephropathy, and neuropathy + +- History of C. difficile infection +- History of seizures +- Small left frontal meningioma +- Hypertension +- GERD +- OSA +- Leg cramps/? RLS +- DJD of neck +- History of dermoid cyst +- Right adrenal mass +. +Past Surgical History: (per OMR) +- Status post cholecystectomy followed by tubal ligation +- Status post left oopherectomy +- Status post appendectomy +. +Past Psychiatric History: (per OMR) +Depression first experienced in high school. First +hospitalization in [**2131**] (after husband's death). History of +cutting and burning self. History of overdose. One course of ECT +in past that was helpful. +. + +Social History: +Widowed, lived in [**Hospital3 **] although most recently has +been at rehab. Has 4 children, several in MA. Smoking: None; +EtOH: Never; Illicits: None + + +Family History: +Family History: +Mom: CAD, stroke +Dad: HTN, DM + +Physical Exam: +On presentation to the MICU: +VS: T 97.9 BP 104/40 HR 83 RR 20 97% 2L +GENERAL: NAD, lethargic but opens eyes to voice and follows +commands +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. PERRLA/EOMI. dryMM. OP clear. Neck Supple, No +LAD, No thyromegaly. +CARDIAC: Regular rhythm, normal rate. Normal S1, S2. 3/6 SEM +best heard at RUSB, no rubs or [**Last Name (un) 549**]. JVP=7cm. +LUNGS: decreased BS at right base but poor effort, no wheezing +or rhonchi +ABDOMEN: +BS, Soft, NT, obese, distended, negative fluid wave +but Dullness to percussion throughout all 4 quadrants, No HSM +EXTREMITIES: No edema or calf pain, 2+ dorsalis pedis/ posterior +tibial pulses. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Lethargice CN 2-12 grossly intact. Preserved +sensation throughout grossly. Moves all 4 extremities(unable to +interact for strength exam) but b/l arms contracted. Increased +tone with all extremities. [**2-9**]+ reflexes, equal BL. Unable to +assess coordination. Gait assessment deferred. +asterixis +PSYCH: unable to assess +. + + +Pertinent Results: +On Admission: [**2153-7-9**] +WBC-3.3* RBC-2.54* HGB-8.0* HCT-23.3* MCV-92 MCH-31.4 MCHC-34.3 +RDW-18.3* +NEUTS-67.5 LYMPHS-26.4 MONOS-5.4 EOS-0.3 BASOS-0.4 PLT COUNT-65* +PT-16.4* PTT-32.4 INR(PT)-1.5* +GLUCOSE-150* UREA N-55* CREAT-5.4*# SODIUM-134 POTASSIUM-4.5 +CHLORIDE-101 TOTAL CO2-24 ANION GAP-14 +LIPASE-40 ALT(SGPT)-11 AST(SGOT)-17 ALK PHOS-98 TOT BILI-1.0 +. +Hct Trend: +[**2153-7-10**] 02:12AM BLOOD Hct-23.0* +[**2153-7-10**] 09:04AM BLOOD Hct-20.9* +[**2153-7-10**] 12:42PM BLOOD Hct-23.4* +[**2153-7-10**] 05:22PM BLOOD Hct-22.7* +[**2153-7-11**] 12:27AM BLOOD Hct-26.8* +[**2153-7-11**] 05:52AM BLOOD Hct-25.8* +. +At [**Month/Day/Year **]: [**2153-8-20**] +WBC-12.1* RBC-3.30* Hgb-10.0* Hct-31.2* MCV-94 MCH-30.2 +MCHC-32.0 RDW-16.2* Plt Ct-893* +Glucose-96 UreaN-19 Creat-0.6 Na-139 K-5.1 Cl-105 HCO3-26 +AnGap-13 +ALT-20 AST-10 AlkPhos-116 TotBili-0.3 +Albumin-2.9* Calcium-8.3* Phos-3.5 Mg-1.5* +tacroFK-6.9 + +Brief Hospital Course: +63 y/o female with NASH cirrhosis, c/b portal hypertension, +grade [**2-9**] esophageal varices s/p TIPS, encephalopathy, recurrent +pleural effusions requiring weekly thoracentesis, and ESRD on HD +who was admitted with GI Bleed. +. +# UGIB: Has h/o NASH cirrhosis c/b varicies s/p banding and EGD +2 weeks prior with severe portal hypertensive gastropathy vs. +GAVE syndrome. Presented with melenotic stools and hematocrit +drop unresponsive to transfusion. EGD showed clotted blood and +known varices/gastropathy with no active bleeding. ? oozing from +gastropathy. Hct stablelized after 2 units pRBCs and was called +out of the ICU to the medicine floor. PPI was continued. +. +Dyspnea: Likely related to reaccumulating pleural effusion. +Required 2 thoracentesis procedures on the medicine service +prior to [**Month/Day (2) **]. Fluid was exudative by lights criteria and +cultures were negative. Likely related to underlying liver +disease. She received one tap for 1 liter post op and has +otherwise been stable. +. +# Fever: Patient was intermittently febrile while on the +medicine service prior to [**Month/Day (2) **]. Culture data and c diff +toxin were unrevealing. She was placed on Vanco and Zosyn +empirically from [**7-15**] to [**7-21**] until [**Month/Year (2) **] for presumed HAP, +but no adequate sputum could be obtained. She had one episode of +fever post [**Month/Year (2) **] that was related to a Klebsiella UTI which +was treated with Zosyn x 5 days, she remained afebrile through +the rest of hospitalizations. +. +# ESRD: Prior to [**Month/Year (2) **], was on TTS HD schedule. Received +liver/kidney [**Month/Year (2) **].Because she was highly sensitized, she +received plasmapheresis and thymoglobulin. The creatinine was +down to 0.6 by time of [**Month/Year (2) **]. +. +# NASH Cirrhosis: On the medicine service, patient was continued +on lactulose, rifaximin, midodrine, ursodiol, nadolol and +bactrim DS for SBP prophylaxis prior to [**Month/Year (2) **]. She received +a combined liver and kidney [**Month/Year (2) **] on [**7-21**] (extending +into [**7-22**]) She was taken to the OR with Drs [**Last Name (STitle) **] and [**Name5 (PTitle) 816**]. +The liver surgery consisted of Orthotopic deceased donor liver +[**Name5 (PTitle) **], piggyback, +portal vein to portal vein anastomosis, common hepatic artery +donor to proper hepatic artery recipient, common bile duct to +common bile duct anastomosis with no T-tube. Splenectomy was +also done to assist with increased PRA for the kidney. +Post operatively her liver enzymes returned to [**Location 213**] very soon +after surgery and remained stable throughtout the +hospitalization. She received routine immunosuppression to +include Cellcept and Prograf as well as the induction Thymo and +solumedrol with plasmapheresis for the highly sensitzed kidney. +She also received IVIg x 3 doses. +. +Nutrition: Patient will continue on tube feeds. Her appetite has +improved over the course of the hospitalization but is still +requiring some supplementation via [**Location 40056**]. +. +# DM2: Continue glargine and SSI. +. +# History of seizure: Leviticetam is continued post op. +. +# Depression/Anxiety: Continue on citalopram (dose increased to +40 mg daily on [**8-19**]) and ativan PRN +. + + +Medications on Admission: +Albuterol Sulfate (0.083 % nebs inhaled q(4) hours prn +Allopurinol 100 mg Tablet PO QOD +Nephrocaps daily +Citalopram 60 mg Tablet by mouth daily +Gabapentin 300 mg Capsule PO QOD +Hydroxyzine HCl 25 mg Tablet PO q8hr prn pruritis +Novolog SS +Lantus 18 units at bedtime +Ipratropium Bromide (0.02 %) q(6) prn +Lactulose 45 CCs by mouth qid +Lamotrigine 100 mg Tablet by mouth at bedtime +Keppra 1,000 mg Tablet by mouth once a day after HD on HD days +Lorazepam 1 mg Tablet by mouth q (8) prn anxiety +Midodrine 5 mg by mouth QTUTHSA (TU,TH,SA) +Nadolol 20 mg Tablet by mouth once a day +Pantoprazole 40 mg Tablet, Delayed Release (E.C.) by mouth every +q12 +Rifaximin 400 mg Tablet PO TID +Renagel 800 mg Tablet by mouth TID +Bactrim DS 800 mg-160 mg Tablet by mouth daily +Ursodiol 600 mg Capsule PO BID +OTC: +Calcium Carbonate-Vitamin D3 [Caltrate-600 Plus Vitamin D3] +600 mg-400 unit Tablet 2 Tablet(s) by mouth once a day +Multivitamin 1 Tablet(s) by mouth once a day (OTC) +. + + +[**Month/Year (2) **] Medications: +1. Levetiracetam 500 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +2. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H (every +6 hours) as needed for pain. +3. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day): Hold for diarrhea. +4. Trimethoprim-Sulfamethoxazole 80-400 mg Tablet Sig: One (1) +Tablet PO DAILY (Daily). +5. Mycophenolate Mofetil 500 mg Tablet Sig: Two (2) Tablet PO +BID (2 times a day). +6. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +7. Miconazole Nitrate 2 % Powder Sig: One (1) Appl Topical TID +(3 times a day) as needed for peri area. +8. Valganciclovir 450 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +9. Loperamide 2 mg Capsule Sig: One (1) Capsule PO TID (3 times +a day) as needed for diarrhea. +10. Prednisone 5 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily): Follow [**Month/Year (2) **] clinic taper. +11. Insulin Glargine 100 unit/mL Solution Sig: Thirty Two (32) +units Subcutaneous at bedtime. +12. Insulin Regular Human 100 unit/mL Solution Sig: per sliding +scale Injection four times a day. +13. Furosemide 20 mg Tablet Sig: One (1) Tablet PO QAM (once a +day (in the morning)). +14. Tacrolimus 1 mg Capsule Sig: Four (4) Capsule PO twice a +day. +15. Citalopram 20 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +16. Lorazepam 0.5 mg Tablet Sig: One (1) Tablet PO twice a day +as needed for agitation/anxiety. + + +[**Month/Year (2) **] Disposition: +Extended Care + +Facility: +[**Hospital1 **] + +[**Hospital1 **] Diagnosis: +NASH cirrhosis +ESRD +s/p combined liver/kidney [**Hospital1 **] + + +[**Hospital1 **] Condition: +Stable/Good + + +[**Hospital1 **] Instructions: +Please call the [**Hospital1 **] clinic at [**Telephone/Fax (1) 673**] for fever > +101, chills, nausea, vomiting, diarrhea, inability to take or +keep down food, fluids or medications. +Labs to be drawn every Monday and Thursday to include CBC, Chem +10, AST, ALT, t bili, Alk Phos, trough Prograf level and U/A +Continue cycled tube feeds via [**Name (NI) 40056**] +PT +Abdominal wound normal saline moist to dry dressing daily +Sacral dressing q 72 hours and PRN + +Followup Instructions: +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 707**], MD, PHD[**MD Number(3) 708**]:[**Telephone/Fax (1) 673**] Date/Time:[**2153-8-29**] +3:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 707**], MD, PHD[**MD Number(3) 708**]:[**Telephone/Fax (1) 673**] Date/Time:[**2153-9-5**] +11:00 +[**Name6 (MD) 2105**] [**Name8 (MD) 2106**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2153-9-14**] +11:00 + + + [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 707**] MD, [**MD Number(3) 709**] + +Completed by:[**2153-8-21**]",174,2153-07-09 22:39:00,2153-08-21 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,UPPER GI BLEED," +63 y/o female with nash cirrhosis, c/b portal hypertension, +grade [**2-9**] esophageal varices s/p tips, encephalopathy, recurrent +pleural effusions requiring weekly thoracentesis, and esrd on hd +who was admitted with gi bleed. +. +# ugib: has h/o nash cirrhosis c/b varicies s/p banding and egd +2 weeks prior with severe portal hypertensive gastropathy vs. +gave syndrome. presented with melenotic stools and hematocrit +drop unresponsive to transfusion. egd showed clotted blood and +known varices/gastropathy with no active bleeding. ? oozing from +gastropathy. hct stablelized after 2 units prbcs and was called +out of the icu to the medicine floor. ppi was continued. +. +dyspnea: likely related to reaccumulating pleural effusion. +required 2 thoracentesis procedures on the medicine service +prior to [**month/day (2) **]. fluid was exudative by lights criteria and +cultures were negative. likely related to underlying liver +disease. she received one tap for 1 liter post op and has +otherwise been stable. +. +# fever: patient was intermittently febrile while on the +medicine service prior to [**month/day (2) **]. culture data and c diff +toxin were unrevealing. she was placed on vanco and zosyn +empirically from [**7-15**] to [**7-21**] until [**month/year (2) **] for presumed hap, +but no adequate sputum could be obtained. she had one episode of +fever post [**month/year (2) **] that was related to a klebsiella uti which +was treated with zosyn x 5 days, she remained afebrile through +the rest of hospitalizations. +. +# esrd: prior to [**month/year (2) **], was on tts hd schedule. received +liver/kidney [**month/year (2) **].because she was highly sensitized, she +received plasmapheresis and thymoglobulin. the creatinine was +down to 0.6 by time of [**month/year (2) **]. +. +# nash cirrhosis: on the medicine service, patient was continued +on lactulose, rifaximin, midodrine, ursodiol, nadolol and +bactrim ds for sbp prophylaxis prior to [**month/year (2) **]. she received +a combined liver and kidney [**month/year (2) **] on [**7-21**] (extending +into [**7-22**]) she was taken to the or with drs [**last name (stitle) **] and [**name5 (ptitle) 816**]. +the liver surgery consisted of orthotopic deceased donor liver +[**name5 (ptitle) **], piggyback, +portal vein to portal vein anastomosis, common hepatic artery +donor to proper hepatic artery recipient, common bile duct to +common bile duct anastomosis with no t-tube. splenectomy was +also done to assist with increased pra for the kidney. +post operatively her liver enzymes returned to [**location 213**] very soon +after surgery and remained stable throughtout the +hospitalization. she received routine immunosuppression to +include cellcept and prograf as well as the induction thymo and +solumedrol with plasmapheresis for the highly sensitzed kidney. +she also received ivig x 3 doses. +. +nutrition: patient will continue on tube feeds. her appetite has +improved over the course of the hospitalization but is still +requiring some supplementation via [**location 40056**]. +. +# dm2: continue glargine and ssi. +. +# history of seizure: leviticetam is continued post op. +. +# depression/anxiety: continue on citalopram (dose increased to +40 mg daily on [**8-19**]) and ativan prn +. + + + ","PRIMARY: [Other specified disorders of stomach and duodenum] +SECONDARY: [End stage renal disease; Hemorrhage of gastrointestinal tract, unspecified; Portal hypertension; Esophageal varices in diseases classified elsewhere, without mention of bleeding; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Other ascites; Unspecified pleural effusion; Pneumonia, organism unspecified; Urinary tract infection, site not specified; Other complications due to renal dialysis device, implant, and graft; Paroxysmal ventricular tachycardia; Hepatic encephalopathy; ; Cardiac arrest; Cirrhosis of liver without mention of alcohol; Other chronic nonalcoholic liver disease; Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled; Background diabetic retinopathy; Anemia in chronic kidney disease; Epilepsy, unspecified, without mention of intractable epilepsy; Esophageal reflux; Obstructive sleep apnea (adult)(pediatric); Dysthymic disorder; Friedl?nder's bacillus infection in conditions classified elsewhere and of unspecified site; Surgical operation with anastomosis, bypass, or graft, with natural or artificial tissues used as implant causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation]" +29035,108831.0,17958,2153-08-21,17957,115770.0,2153-05-16,Discharge summary,"Admission Date: [**2153-5-14**] [**Year/Month/Day **] Date: [**2153-5-16**] + +Date of Birth: [**2089-12-13**] Sex: F + +Service: MEDICINE + +Allergies: +Erythromycin Base / Indomethacin / Actonel / Reglan + +Attending:[**First Name3 (LF) 3561**] +Chief Complaint: +Hypoxia and hypotension s/p thoracentesis + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +63 F with NASH cirrhosis, recurrent pleural effusions, DM, ESRD +on TTS schedule who was sent to the ER after 2 liter +thoracentesis done by radiology. Her oxygen saturation dropped +to the high 80s and she was transiently hypotensive to 80s +systolic. She denied lightheadedness, dizziness, chest pain, +nausea, diaphoresis, her only complaint was of pleurisy on +inspiration. + +In the ER her blood pressure was stable in the 90s systolic (b/l +90-100s), CXR with no PTX, 99% 4L/NC. Clinically without +complaints, asking for food. Guiaic negative. No other +complaints. No fluids given. Admitted to MICU for close +observation of hemodynamics. +. +Review of systems is otherwise negative other than HPI. In the +ICU she had no complaints other than pleurisy. + + +Past Medical History: +NASH cirrhosis: Liver bx [**2152-9-6**] = Stage IV cirrhosis, Grade 2 +inflammation, complicated by portal HTN +--Esophageal varicies (grade I and II, s/p banding), s/p TIPS in + +[**9-15**] +--History of encephalopathy +--History of ascites +- Anemia +- Thrombocytopenia +- ESRD on HD due to diabetes and contrast-induced nephropathy +- Type 2 diabetes with retinopathy, nephropathy, and neuropathy +- History of C. difficile infection +- History of seizures +- Small left frontal meningioma +- Hypertension +- GERD +- OSA +- Leg cramps/? RLS +- DJD of neck +- History of dermoid cyst +- Right adrenal mass +. +Past Surgical History: +- Status post cholecystectomy followed by tubal ligation +- Status post left oopherectomy +- Status post appendectomy +. +Past Psychiatric History: +Depression first experienced in high school. First +hospitalization in [**2131**] (after husband's death). History of +cutting and burning self. History of overdose. One course of ECT + +in past that was helpful. + + +Social History: +Social History: +Widowed, lived in [**Hospital3 **] although most recently has +been at rehab. Has 4 children, several in MA. +Smoking: None +EtOH: Never +Illicits: None + + +Family History: +Family History: +Mom: CAD, stroke +Dad: HTN, DM + +Physical Exam: +Tmax: 36.7 ??????C (98 ??????F) +Tcurrent: 36.7 ??????C (98 ??????F) +HR: 58 (56 - 62) bpm +BP: 98/34(49) {76/34(47) - 100/47(59)} mmHg +RR: 15 (11 - 15) insp/min +SpO2: 97% + +General Appearance: No acute distress +Eyes / Conjunctiva: PERRL +Head, Ears, Nose, Throat: Normocephalic +Lymphatic: Cervical WNL, Supraclavicular WNL +Cardiovascular: (S1: Normal), (S2: Normal), (Murmur: Systolic) +Peripheral Vascular: (Right radial pulse: Present), (Left radial +pulse: Present), (Right DP pulse: Present), (Left DP pulse: +Present) +Respiratory / Chest: (Expansion: Symmetric), (Percussion: +Dullness : RLL), (Breath Sounds: Diminished: RLL) +Abdominal: Soft, Non-tender, Bowel sounds present, Distended, +ascites present +Extremities: Right: 1+, Left: 1+ +Skin: Not assessed +Neurologic: Attentive, Follows simple commands, Responds to: Not +assessed, Oriented (to): x3, Movement: Not assessed, Tone: Not +assessed + + +Pertinent Results: +COMPARISON: [**2153-4-29**]. + +FINDINGS: There is no pneumothorax. There is small residual +pleural effusion +on the right. Left lung is clear. There is no left effusion. +Heart and +mediastinal contours are stable. Right-sided tunneled catheter +is again +noted, and the tip is situated within the right atrium. A tip is +noted, and +projects over the expected location within the liver. Osseous +structures are +stable. + +IMPRESSION: + +No pneumothorax. +------------ +[**5-15**] +CHEST PORTABLE AP + +REASON FOR EXAM: 63-year-old woman with re-expansion pulmonary +edema, assess +change. + +Since yesterday, right middle lobe and right lower lobe alveolar +opacity +decreased. Bilateral pleural effusions are unchanged, still +small, more +marked on the right. Right hemodialysis catheter still ends in +the right +atrium. Clips in the upper abdomen are unchanged. There is no +other change. + + +Brief Hospital Course: +63 F with cirrhosis, ESRD s/p thoracentesis who presents with +hypoxia and hypotension in setting likely re-expansion pulmonary +edema +. +#. Hypoxia- patient currently 99% on 2L and comfortable. Suspect +she had some desaturation in setting of re- expansion edema +which has stabilized. No evidence of pneumothorax on multiple +CXR, there is re-accumulation of fluid in the right lung. She +was monitored for 48 hours in the ICU and had stable blood +pressure and oxygen saturation on 2 liters of oxygen. She was +discharged to rehab facility. She should have future +thoracentesis by interventional pulmonary in order to follow +trans pulmonary pressures to avoid re-expansion pulmonary edema. +. + +# Hypotension- patient back to baseline, suspect transient +hypotension in setting volume shifts after thoracentesis. +Baseline systolic pressure 90s. +. + +# ESRD- [**3-12**] diabetes, continue phos binder, was dialyzed on [**5-15**] +with 3 liters removed. +- call renal in AM, due for HD +- continued midodrine with HD +. + +# Cirrhosis- on transplant list +- Encephalopathy- continued lactulose and rifaximin +- SBP- h/o prior SBP, continued Bactrim DS ppx +- ascites- off diuretics, intermittent PC as indicated, none +this hospitalization +- varices- nadolol +- anemia- cont PPI +. + +# Diabetes- continued lantus and humalog SS +. + +# Seizures- continued lamictal +. + +# Depression- continued celexa + +CODE STATUS: confimred FULL CODE + +Medications on Admission: +Acetaminophen prn +Lactulose 30cc qid +Lamotrigine 100 mg qhs +Pantoprazole 40 mg daily +Allopurinol 100 mg qod +Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY +Citalopram 20 mg Tablet Sig: Two (2) Tablet PO DAILY +Ursodiol 300 mg Capsule Sig: Two (2) Capsule PO BID +Hydroxyzine HCl 25 mg Tablet Sig: One (1) Tablet PO Q8H prn +Lorazepam 0.5 mg q8h prn +Gabapentin 300 mg daily +Sevelamer HCl 800mg po tid +Cholecalciferol 800 units daily +Rifaximin 200 mg po tid +Albuterol prn +Ipratropium prn +B-Complex with Vitamin C po daily +Insulin Glargine 20 units QHS +Nadolol 20 mg Tablet Sig: Two (2) Tablet PO DAILY +Keppra 1,000 mg Tablet Sig: One (1) Tablet PO once a day +Docusate Sodium 100 mg PO BID +Bactrim DS 1 tab daily +Midodrine 5 mg Tablet Sig: One (1) Tablet PO QTUTHSA +Zolpidem 5 mg Tablet Sig: 0.5 Tablet PO HS +Insulin Lispro Subcutaneous + +[**Month/Day (4) **] Medications: +1. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO QID (4 +times a day). +2. Lamotrigine 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +4. Allopurinol 100 mg Tablet Sig: One (1) Tablet PO EVERY OTHER +DAY (Every Other Day). +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every six (6) +hours as needed for pain. +7. Citalopram 20 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +8. Ursodiol 300 mg Capsule Sig: Two (2) Capsule PO BID (2 times +a day). +9. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO Q48H (every +48 hours). +10. Hydroxyzine HCl 25 mg Tablet Sig: One (1) Tablet PO Q6H +(every 6 hours) as needed. +11. Lorazepam 0.5 mg Tablet Sig: One (1) Tablet PO every eight +(8) hours as needed. +12. Sevelamer Carbonate 800 mg Tablet Sig: One (1) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +13. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +14. Rifaximin 200 mg Tablet Sig: Two (2) Tablet PO TID (3 times +a day). +15. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed. +16. Ipratropium Bromide 0.02 % Solution Sig: One (1) Inhalation +Q6H (every 6 hours). +17. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +18. Insulin Glargine 100 unit/mL Cartridge Sig: Twenty (20) +Subcutaneous at bedtime. +19. Insulin Lispro 100 unit/mL Cartridge Sig: as directed +Subcutaneous four times a day: per sliding scale. +20. Nadolol 20 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). +21. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +22. Trimethoprim-Sulfamethoxazole 160-800 mg Tablet Sig: One (1) +Tablet PO DAILY (Daily). +23. Midodrine 5 mg Tablet Sig: One (1) Tablet PO 3X/WEEK +(TU,TH,SA). +24. Zolpidem 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime) +as needed for insomnia. + + +[**Month/Day (4) **] Disposition: +Extended Care + +Facility: +[**Last Name (LF) 2670**] , [**First Name3 (LF) 5871**] + +[**First Name3 (LF) **] Diagnosis: +Re-expansion pulmonary edema + +[**First Name3 (LF) **] Condition: +Stable + +[**First Name3 (LF) **] Instructions: +You were in the ICU for monitoring after fluid removal of your +lung. Your vitals were stable. + +Follow up with the liver doctors [**First Name (Titles) **] [**Last Name (Titles) **]. + +Followup Instructions: +Provider: [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 44**] +Date/Time:[**2153-6-22**] 11:30 + + + +",97,2153-05-14 22:41:00,2153-05-16 14:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,HYPOXIA," +63 f with cirrhosis, esrd s/p thoracentesis who presents with +hypoxia and hypotension in setting likely re-expansion pulmonary +edema +. +#. hypoxia- patient currently 99% on 2l and comfortable. suspect +she had some desaturation in setting of re- expansion edema +which has stabilized. no evidence of pneumothorax on multiple +cxr, there is re-accumulation of fluid in the right lung. she +was monitored for 48 hours in the icu and had stable blood +pressure and oxygen saturation on 2 liters of oxygen. she was +discharged to rehab facility. she should have future +thoracentesis by interventional pulmonary in order to follow +trans pulmonary pressures to avoid re-expansion pulmonary edema. +. + +# hypotension- patient back to baseline, suspect transient +hypotension in setting volume shifts after thoracentesis. +baseline systolic pressure 90s. +. + +# esrd- [**3-12**] diabetes, continue phos binder, was dialyzed on [**5-15**] +with 3 liters removed. +- call renal in am, due for hd +- continued midodrine with hd +. + +# cirrhosis- on transplant list +- encephalopathy- continued lactulose and rifaximin +- sbp- h/o prior sbp, continued bactrim ds ppx +- ascites- off diuretics, intermittent pc as indicated, none +this hospitalization +- varices- nadolol +- anemia- cont ppi +. + +# diabetes- continued lantus and humalog ss +. + +# seizures- continued lamictal +. + +# depression- continued celexa + +code status: confimred full code + + ","PRIMARY: [Acute edema of lung, unspecified] +SECONDARY: [Unspecified pleural effusion; Portal hypertension; End stage renal disease; Esophageal varices in diseases classified elsewhere, without mention of bleeding; Acute respiratory failure; Cirrhosis of liver without mention of alcohol; Other chronic nonalcoholic liver disease; Other iatrogenic hypotension; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Obstructive sleep apnea (adult)(pediatric); Diabetes with neurological manifestations, type II or unspecified type, not stated as uncontrolled; Polyneuropathy in diabetes; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled; Background diabetic retinopathy; Esophageal reflux; Anemia in chronic kidney disease]" +29495,182822.0,23427,2126-01-30,23403,152287.0,2125-11-13,Discharge summary,"Admission Date: [**2125-11-6**] Discharge Date: [**2125-11-13**] + +Date of Birth: [**2062-4-14**] Sex: F + +Service: UROLOGY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 824**] +Chief Complaint: +1.4cm right renal calculus + +Major Surgical or Invasive Procedure: +s/p right ureteroscopy, laser lithotripsy + + +History of Present Illness: +63F who underwent a renal ultrasound in [**Country 651**] for back pain +approximately five years ago that showed some kind of kidney +stone and maybe hydronephrosis, per the patient; the history is +unclear. Since that time, she denies any further symptoms and +currently is not in pain. She also denies any nausea or +vomiting, difficulty with her urination or fevers and chills. +She did undergo a CT scan of abdomen and pelvis on [**8-31**] +with and without contrast, which showed a 14 mm right upper pole +nonobstructing calculus with moderate right upper pole cortical +thinning. + +Past Medical History: +Her past medical history is notable for hypertension and a +pacemaker that was placed for apparently bradycardia, per the +patient. She has been seen by Dr. [**Last Name (STitle) **] in Cardiology for +chest pain that was not concerning. + + +Social History: +She reports no history of tobacco use and rare alcohol. The +patient is not currently working. + + +Family History: +Her family history is notable for heart disease, but no kidney +stones. + + +Physical Exam: +AVSS, BP 105/75 +NAD, NCAT +EOM full, PERRL +Neck supple, no LAD +Chest with bibasilar crackles, no wheezes +RRR, no MRG +Abdomen soft, minimally distended, NT, NABS +LE WWP, trace peripheral edema + +Pertinent Results: +CHEST (PORTABLE AP) [**2125-11-8**] 2:59 AM + +CHEST (PORTABLE AP) + +Reason: 300 + +[**Hospital 93**] MEDICAL CONDITION: +63 year old woman with septic shock, flash edema +REASON FOR THIS EXAMINATION: +Effusion, PNA +CLINICAL INDICATION: 63-year-old woman with septic shock and +flash edema, evaluate for effusion or pneumonia. + +COMPARISON: [**2125-11-7**]. + +SEMI-UPRIGHT CHEST X-RAY: Compared with [**2125-11-7**] there +is stable congestive heart failure with large pleural effusions +right greater than left. Pacemaker device and right kidney stent +are stable. A right There is a slight increase in pulmonary +edema. + +IMPRESSION: Slightly increased moderately severe pulmonary edema +right greater than left. Stable bilateral pleural effusions +right greater than left. Coexistant pneumonia cannot be +excluded. +******************** + +PORTABLE ABDOMEN [**2125-11-7**] 8:08 AM + +PORTABLE ABDOMEN + +Reason: eval for sbo + +[**Hospital 93**] MEDICAL CONDITION: +63 year old woman with SOB/pulmonary edema and abdominal +discomfort +REASON FOR THIS EXAMINATION: +eval for sbo +STUDY: Portable abdomen. + +INDICATION: A 63-year-old female with shortness of +breath/pulmonary edema presenting with abdominal discomfort. +Status post small-bowel obstruction. + +COMPARISONS: CT dated [**2125-8-31**]. + +FINDINGS: A right ureteral stent is identified. A pigtail loop +can be visualized projecting over the stated area of the +bladder. The upper pigtail loop appears slightly unfolded, but +is probably within the renal pelvis. On these two supine views, +there are no distended loops of small bowel. The bowel gas +pattern is overall nonspecific. The soft tissues and osseous +structures are grossly unremarkable. + +IMPRESSION: No evidence of obstruction. + +******************** +ECHO: [**2125-11-7**] +The left atrium is elongated. No atrial septal defect is seen by +2D or color Doppler. The estimated right atrial pressure is +0-10mmHg. Left ventricular wall thickness, cavity size and +regional/global systolic function are normal (LVEF >55%) +Transmitral Doppler and tissue velocity imaging are consistent +with normal LV diastolic function. There is no ventricular +septal defect. The right ventricular cavity is mildly dilated. +Right ventricular systolic function is normal. The ascending +aorta is mildly dilated. The aortic valve leaflets (3) are +mildly thickened but aortic stenosis is not present. No aortic +regurgitation is seen. The mitral valve leaflets are mildly +thickened. No mass or vegetation is seen on the mitral valve. +Mild (1+) mitral regurgitation is seen. The tricuspid valve +leaflets are mildly thickened. There is moderate pulmonary +artery systolic hypertension. There is a trivial/physiologic +pericardial effusion. + +******************** + AEROBIC BOTTLE (Final [**2125-11-12**]): + THIS IS A CORRECTED REPORT [**2125-11-12**] 11:30AM. + REPORTED BY PHONE TO [**First Name8 (NamePattern2) **] [**Doctor Last Name **] [**2125-11-12**] 11:35AM. + NO GROWTH. + PREVIOUSLY REPORTED AS GRAM NEGATIVE DIPLOCOCCI [**2125-11-12**] +11:30AM. + + ANAEROBIC BOTTLE (Final [**2125-11-10**]): + REPORTED BY PHONE TO [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) 60045**] 4I 21:15 [**2125-11-7**]. + ESCHERICHIA COLI. FINAL SENSITIVITIES. + WARNING! This isolate is an extended-spectrum +beta-lactamase + (ESBL) producer and should be considered resistant to +all + penicillins, cephalosporins, and aztreonam. Consider +Infectious + Disease consultation for serious infections caused by + ESBL-producing species. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ESCHERICHIA COLI + | +AMPICILLIN------------ =>32 R +AMPICILLIN/SULBACTAM-- =>32 R +CEFAZOLIN------------- =>64 R +CEFEPIME-------------- R +CEFTAZIDIME----------- R +CEFTRIAXONE----------- =>64 R +CEFUROXIME------------ =>64 R +CIPROFLOXACIN--------- =>4 R +GENTAMICIN------------ <=1 S +IMIPENEM-------------- <=1 S +MEROPENEM-------------<=0.25 S +PIPERACILLIN---------- =>128 R +PIPERACILLIN/TAZO----- <=4 S +TOBRAMYCIN------------ <=1 S +TRIMETHOPRIM/SULFA---- <=1 S + + +Brief Hospital Course: +Here for semi-elective ureteroscopy and laser lithotripsy for +>1cm renal pelvis stone. She was feeling well, in her usual +state of health and took her antihypertensive medications this +morning. Her Pre-op Vs were T 99.1, P 71, BP 149/80, RR 20, 100% +on RA. The procedure begatn at 15:35 and ended at 17:08, and +required GETA (with propofol for sedation) and was +uncomplicated. + +Post-operatively she was hypertensive with BP 190/100 which +responded to 5mg Iv labetalol; however her BP trended down by +7pm to the low 100's with HR a-paced at 70. At 2100 she was +febrile to 101.8 and had severe nausea and vomiting for which +she was given 200mcg fentanyl, 2mg midazolam, 1mg haldol for +nausea, 125mg demerol for shakes, 3.25mg promethazine, and 4mg +zofran along with 240mg gentamycin and 1g vancomycin for +presumed urosepsis. Her BP then trended down to the 80's-90's +where it remained despite 3.5L IVF in the post-operative +setting. Her oxygen saturation was also noted to be in the low +90's on 2L N/C, briefly requiring 6L nasal canula and then back +to 2-3L n/c. + +ID: Placed empirically on vanc and gent, then changed to vanc +and cefepime on POD1. By the end of POD1, blood cx grew out GNR +in the anaerobic bottle, resistant to ceftriaxone, cipro, levo. +Since sensitivities to cefepime were unknown, but this organism +was known to be sensitive to gentamycin, on POD2, the pt was +again placed on gent. After 3 doses, abx were again changed to +from gent to meropenem on POD3. In addition the pt remained on +vancomycin. Flagyl was added due to concern for C.diff on POD2 +after an episode of diarrhea. POD4, vanc and flagyl were +discontinued and the pt was maintained on meropenem until +discharge, after cultures grew E.coli with extended resistance, +but susceptibility to [**Last Name (un) 2830**] and ertapenem. The day of discharge +POD7, the pt received one dose of ertapenem in house; it was +arranged for her to receive daily dosing as an outpatient. +Follow up after antibiotics with urology was arranged. + +CV: Baseline BP unknown, but in [**Name (NI) 13042**], pt was initally +hypertensive as above and then hypotensive after sedation and +BB. The night of admission the pt received 10L IVF to sustain +her pressures. POD1-2 BPs primarily ranged in 80-90s systolic +without fluid boluses or pressors. Urine output remained high +and pt was mentating fine. By POD3, the SBP rose to 110s. +Pressors were not used. On POD2, pt also went into afib with +RVR, 10mg iv lopressor was used in conjunction with PO lopressor +to control the rate. The pt spontaneously reverted back to NSR +on POD2 later in the day. On POD4, the pt again had an episode +of Afib, rate controlled with PO lopressor, which again +spontaneously converted to NSR. After this date she maintained +sinus rhythm until discharge. Medicine was consulted and they +recommended no acute treatment during this hospitalization and +follow up with her PCP for management of this rhythm. + +Pulm: Pt went into flash pulmonary edema the evening of +admission after receiving aggressive IVF resuscitation. Her O2 +requirement increased from 2LNC to 15L/min per non-rebreather. +By the following morning, after being diuresed with IV lasix, +the pt was on 4L via nasal cannula and sating 95-100%. By POD4, +the pt was saturating well on room air, and she remained off +supplemental oxygen for the remainder of the hospitalization. + +GI: On POD1, the pt complained of moderate lower abdominal pain. + She was distended on exam. KUB demonstrated a non-obstructive +gas pattern with gas in the sigmoid colon. By POD2, the pt was +passing flatus and her distention had reduced. + +Medications on Admission: +metoprolol 12.5 [**Hospital1 **] +isosorbide dinitrate [**Hospital1 **] +aspirin + +Discharge Medications: +1. Metoprolol Tartrate 25 mg Tablet Sig: 0.5 Tablet PO BID (2 +times a day). +2. Isosorbide Dinitrate 10 mg Tablet Sig: One (1) Tablet PO BID +(2 times a day). +3. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H (every +6 hours) as needed for temp>101, pain. +4. Ertapenem 1 gram Recon Soln Sig: One (1) gram Intravenous +once a day for 9 days. +Disp:*9 grams* Refills:*0* +5. Albuterol 90 mcg/Actuation Aerosol Sig: One (1) puff +Inhalation every six (6) hours as needed for shortness of breath +or wheezing. +Disp:*3 inhalers* Refills:*1* +6. Saline Flush 0.9 % Syringe Sig: [**5-3**] ml Injection SASH, prn. +Disp:*180 ml* Refills:*2* +7. Heparin Flush 100 unit/mL Kit Sig: [**2-26**] ml Intravenous SASH, +prn. +Disp:*90 ml* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +s/p right ureteroscopy, laser lithotripsy, urosepsis + + +Discharge Condition: +good + + +Discharge Instructions: +You may shower and bathe normally. Do not drive or drink +alcohol if taking narcotic pain medication. Resume all of your +home medications, but please avoid aspirin/advil for one week. +Call your Urologist's office ([**Telephone/Fax (1) 164**]) to schedule a +follow-up appointment in [**1-27**] weeks, or if you have any +questions. If you have fevers > 101.5 F, vomiting, severe +abdominal pain, or inability to urinate, call your doctor or go +to the nearest emergency room. + + +Followup Instructions: +Call [**Telephone/Fax (1) 164**] to arrange follow up after you have completed +your antibiotics in [**1-27**] weeks. + + + +",78,2125-11-06 17:26:00,2125-11-13 13:13:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOME HEALTH CARE,KIDNEY STONES," +here for semi-elective ureteroscopy and laser lithotripsy for +>1cm renal pelvis stone. she was feeling well, in her usual +state of health and took her antihypertensive medications this +morning. her pre-op vs were t 99.1, p 71, bp 149/80, rr 20, 100% +on ra. the procedure begatn at 15:35 and ended at 17:08, and +required geta (with propofol for sedation) and was +uncomplicated. + +post-operatively she was hypertensive with bp 190/100 which +responded to 5mg iv labetalol; however her bp trended down by +7pm to the low 100s with hr a-paced at 70. at 2100 she was +febrile to 101.8 and had severe nausea and vomiting for which +she was given 200mcg fentanyl, 2mg midazolam, 1mg haldol for +nausea, 125mg demerol for shakes, 3.25mg promethazine, and 4mg +zofran along with 240mg gentamycin and 1g vancomycin for +presumed urosepsis. her bp then trended down to the 80s-90s +where it remained despite 3.5l ivf in the post-operative +setting. her oxygen saturation was also noted to be in the low +90s on 2l n/c, briefly requiring 6l nasal canula and then back +to 2-3l n/c. + +id: placed empirically on vanc and gent, then changed to vanc +and cefepime on pod1. by the end of pod1, blood cx grew out gnr +in the anaerobic bottle, resistant to ceftriaxone, cipro, levo. +since sensitivities to cefepime were unknown, but this organism +was known to be sensitive to gentamycin, on pod2, the pt was +again placed on gent. after 3 doses, abx were again changed to +from gent to meropenem on pod3. in addition the pt remained on +vancomycin. flagyl was added due to concern for c.diff on pod2 +after an episode of diarrhea. pod4, vanc and flagyl were +discontinued and the pt was maintained on meropenem until +discharge, after cultures grew e.coli with extended resistance, +but susceptibility to [**last name (un) 2830**] and ertapenem. the day of discharge +pod7, the pt received one dose of ertapenem in house; it was +arranged for her to receive daily dosing as an outpatient. +follow up after antibiotics with urology was arranged. + +cv: baseline bp unknown, but in [**name (ni) 13042**], pt was initally +hypertensive as above and then hypotensive after sedation and +bb. the night of admission the pt received 10l ivf to sustain +her pressures. pod1-2 bps primarily ranged in 80-90s systolic +without fluid boluses or pressors. urine output remained high +and pt was mentating fine. by pod3, the sbp rose to 110s. +pressors were not used. on pod2, pt also went into afib with +rvr, 10mg iv lopressor was used in conjunction with po lopressor +to control the rate. the pt spontaneously reverted back to nsr +on pod2 later in the day. on pod4, the pt again had an episode +of afib, rate controlled with po lopressor, which again +spontaneously converted to nsr. after this date she maintained +sinus rhythm until discharge. medicine was consulted and they +recommended no acute treatment during this hospitalization and +follow up with her pcp for management of this rhythm. + +pulm: pt went into flash pulmonary edema the evening of +admission after receiving aggressive ivf resuscitation. her o2 +requirement increased from 2lnc to 15l/min per non-rebreather. +by the following morning, after being diuresed with iv lasix, +the pt was on 4l via nasal cannula and sating 95-100%. by pod4, +the pt was saturating well on room air, and she remained off +supplemental oxygen for the remainder of the hospitalization. + +gi: on pod1, the pt complained of moderate lower abdominal pain. + she was distended on exam. kub demonstrated a non-obstructive +gas pattern with gas in the sigmoid colon. by pod2, the pt was +passing flatus and her distention had reduced. + + ","PRIMARY: [Other postoperative infection] +SECONDARY: [Septicemia due to escherichia coli [E. coli]; Severe sepsis; Septic shock; Defibrination syndrome; Cardiac complications, not elsewhere classified; Atrial fibrillation; ; Cardiac pacemaker in situ; Unspecified essential hypertension; Calculus of kidney]" +30341,121351.0,30890,2145-07-31,30889,174592.0,2145-06-18,Discharge summary,"Admission Date: [**2145-5-28**] Discharge Date: [**2145-6-18**] + +Date of Birth: [**2084-3-2**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 5552**] +Chief Complaint: +Dehydration. + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +Mr. [**Known lastname **] is a 61 year old man with metastatic esophageal +cancer to liver and lung presents from clinic with dehydration +and severe mucositis. He is s/p initiation of cycle 1 of ECX +(epirubicin, cisplatin, and xeloda) on [**5-20**]. Since his +treatment, he has been feeling fatigued and developed a sore +throat and mouth sores. He has been able to eat and drink +although drinking sometimes makes him nauseated. He was +prescribed magic mouthwash and did not noticed much improvement. + Patietn also states that he feels confused sometims and with a +slow mind. He had dairrhea in the morning with normal color, but +watery stool. He denies any sick contacts or exposure to people +in nursing homes, children or other infectious agents. +. +He had planned on coming into the outpatient treatment area for +IVFs, but because he has been feeling so unwell, he presented in +clinic today for evaluation. +. +In clinic, he was found to be orthostatic and appeared +dehydrated on exam. He was noted to have oral thrush. He was +given 2L NS, zofran 8 mg IV and nystatin 5 cc as well as +diflucan 200 mg. he was seen by Dr. [**Last Name (STitle) **]. He is now being +admitted for rehydration and treatment of his mucositis and +thrush. + +Past Medical History: +PAST ONCOLOGIC HISTORY: +====================== +He initially presented in [**11/2142**] due to dysphagia and weight +loss. At that time, he had a barium swallow, which showed a +pinpoint narrowing of his distal esophagus. He had endoscopy +and underwent dilatation of this stricture. He did not have +much improvement with the dilatation and in [**Month (only) 116**] of this year +underwent a second dilatation once again with no improvement. +He had motility tests, which were most consistent with +achalasia. In [**Month (only) **], he underwent a Botox injection to the +narrowing in order to help to release it. He had a CT scan +after this which showed a 1.5 cm gastrohepatic lymph node. On +[**2143-8-28**] he underwent an upper endoscopy on which they saw +distal esophageal narrowing. They also performed multiple +biopsies of the area of narrowing. Of note, they saw some +ulceration in the GE junction and a thick abnormal fold +concerning for esophageal or gastric cardia cancer. The biopsy +showed moderate to poorly differentiated adenocarcinoma. After +this he underwent endoscopic ultrasound, however, they were +unable to pass the ultrasound probe beyond the stricture. He +has had a port, g-tube, and esophageal stent +placed. He started treatment with 5-FU and Cisplatin on [**2143-10-10**] +with concurrent radiation therapy. Radiation was completed on +[**2143-11-26**]. He was admitted from [**2143-11-26**] to the [**2143-12-3**] +with febrile neutropenia and dehydration. He underwent an +esophagectomy on [**2144-1-20**]. Pathology from this showed a +metastatic adenocarcinoma with 4/6 perigastric lymph nodes +positive, and a separate foci of tumor in the adjacent adipose +tissue. He completed treatment in [**2144-1-4**]. He had liver +lesions noted on a CT scan [**2145-1-16**]. He had these biopsied on +[**2145-1-27**] and the pathology came back as consistent with +metastasis from esophageal cancer. +. +PAST MEDICAL HISTORY: +==================== +- Esophageal cancer- moderate to poorly differentiated +adenocarcinoma; Rec'd 5-FU/cisplatin with concurrent XRT in +[**10-11**], now s/p minimally invasive esophagectomy [**1-10**]. +- h/o atrial fibrillation +- h/o S. viridans bacteremia +- Sinusitis, status post surgery +- Hypertension +- Vocal cord paralysis + +Social History: +He originally moved from [**Country 6171**] 17 years ago. Married, 2 +children. Teaches French and Spanish. He used to smoke a pack a +day, but quit 15 years ago. He used to drink a couple of glasses +of wine with dinner each night, but not since diagnosis. + +Family History: +He has a father with pancreatic cancer who died at the age of +70. + +Physical Exam: +Vitals - T: 98.1 BP: 104/74 HR: 67 RR: 16 02 sat: 100% on RA +. +GENERAL: NAD, very pelasant gentleman, hoarse, very french +accent +SKIN: warm and well perfused, no excoriations or lesions, no +rashes +HEENT: AT/NC, EOMI, PERRLA, anicteric sclera, pink conjunctiva, +patent nares, MMM, good dentition, nontender supple neck, no +LAD, no JVD +CARDIAC: RRR, S1/S2, no mrg +LUNG: CTAB +ABDOMEN: nondistended, +BS, nontender in all quadrants, no +rebound/guarding, no hepatosplenomegaly +M/S: moving all extremities well, no cyanosis, clubbing or +edema, no obvious deformities +PULSES: 2+ DP pulses bilaterally +NEURO: CN II-XII intact, strenght [**6-8**] in upper and lower +extremities, DTRs [**6-8**], [**Name2 (NI) 73082**] 27 + + +Pertinent Results: +On Admission: +[**2145-5-28**] 10:00AM WBC-2.9*# RBC-4.84 HGB-15.0 HCT-43.9 MCV-91 +MCH-30.9 MCHC-34.1 RDW-13.8 +[**2145-5-28**] 10:00AM PLT SMR-VERY LOW PLT COUNT-35*# +[**2145-5-28**] 10:00AM GRAN CT-2240 +[**2145-5-28**] 10:00AM ALT(SGPT)-100* AST(SGOT)-51* ALK PHOS-75 TOT +BILI-1.4 DIR BILI-0.3 INDIR BIL-1.1 +[**2145-5-28**] 10:00AM ALBUMIN-3.5 PHOSPHATE-3.5 MAGNESIUM-2.2 +[**2145-5-28**] 10:00AM UREA N-36* CREAT-1.0 SODIUM-138 POTASSIUM-3.6 +CHLORIDE-102 TOTAL CO2-27 ANION GAP-13 +[**2145-5-28**] 10:00AM GRAN CT-2240 + +Pertinent Interim/Discharge Labs +[**2145-6-18**] 12:23AM BLOOD WBC-12.3* RBC-3.46* Hgb-10.7* Hct-30.5* +MCV-88 MCH-31.0 MCHC-35.2* RDW-18.6* Plt Ct-228 +[**2145-6-14**] 12:00AM BLOOD WBC-19.3* RBC-3.03* Hgb-9.4* Hct-28.2* +MCV-93 MCH-30.9 MCHC-33.2 RDW-17.9* Plt Ct-98* +[**2145-6-13**] 12:00AM BLOOD PT-15.5* INR(PT)-1.4* +[**2145-6-8**] 09:36AM BLOOD PT-28.0* PTT-31.1 INR(PT)-2.8* +[**2145-6-6**] 12:00AM BLOOD Gran Ct-253* +[**2145-6-7**] 12:00AM BLOOD Gran Ct-704* +[**2145-6-9**] 12:00AM BLOOD Gran Ct-7521 +[**2145-6-18**] 12:23AM BLOOD Glucose-91 UreaN-19 Creat-0.5 Na-134 +K-4.4 Cl-103 HCO3-24 AnGap-11 +[**2145-6-15**] 12:00AM BLOOD ALT-27 AST-32 LD(LDH)-292* AlkPhos-160* +TotBili-2.1* +[**2145-6-18**] 12:23AM BLOOD Calcium-7.0* Phos-3.5 Mg-1.9 +[**2145-6-15**] 12:00AM BLOOD Albumin-2.0* Calcium-6.9* Phos-3.1 Mg-1.9 + +CT abdomen/pelvis [**5-30**]: +1. No evidence of diverticulitis, abscess, or any acute +pathology to explain LLQ pain. +2. New wedge-shaped hypodensities within the spleen, likely +infarcts given relatively rapid appearance from the prior study. + +3. Although incompletely assessed due to collapsed bowel, +apparent wall thickening of the ascending colon which may +represent bowel wall edema. No secondary signs of inflammation +(ie no fat stranding). + +CXR [**6-3**]: +As compared to the previous radiograph, there is increasing +opacity +at the left lung base, combined with a newly appeared blunting +of the left +costophrenic sinus, presumably due to effusion. The size of the +cardiac +silhouette is unchanged. Unchanged normal right lung, unchanged +Port-A-Cath system. + +CT chest [**6-4**]: +1. New diffuse transverse colon wall thickening and surrounding +inflammatory change consistent with colitis, only partially +visualized. Further evaluation with dedicated CT enterography of +the abdomen and pelvis may be obtained for further evaluation. +2. New, small left, and trace right, pleural effusions. +3. New tree-in-[**Male First Name (un) 239**] opacities in the right lower lobe with mild +improvement in right upper lobe tree-in-[**Male First Name (un) 239**] opacities. These +findings may be due to +aspiration. + +TTE [**6-8**]: +No vegetations seen (suboptimal-quality study). Mild mitral +regurgitation. Normal global and regional biventricular systolic +function. + +RUE U/S [**6-8**]: +DVT involving the right distal brachial vein, as well as the +cephalic vein. + +CXR [**6-9**]: +Compared to [**6-3**], there is more opacification in the left +lower lobe, +which could be worsening atelectasis or pneumonia particularly +due to recent aspiration. There has also been increase in +diameter of the cardiac +silhouette and the azygos vein which may indicate volume +overload but there is no pulmonary edema. + +MICRO +[**6-1**] blood cx: Strep Pneumoniae + +Brief Hospital Course: +1. Pneumococcal infection: While the patient was neutropenic, he +was febrile once. Cultures were sent and he was started on +empiric cefepime. Imaging suggested a LLL pneumonia, and blood +cultures grew GPC, for which vancomycin was added. The GPC were +speciated as S. pneumoniae. TTE showed no vegetations. No +further blood cultures were positive, and his antibiotics were +eventually narrowed to ceftriaxone alone for a 14 day course, +starting at the resolution of neutropenia. For easier dosing at +home, he was changed to Cefpodoxine to finish course after +discharge. + +2. Mucositis: Unable to tolerate PO and was resuscitated with +IVF. He was started on oral lidocaine and gelclairm as well as +oral fluconazole and nystatin for [**Female First Name (un) 564**]. He was later taken +off the fluconazole as it elevated his transaminases and changed +to micafungin. However, this was also stopped as it elevated his +bilirubin. IV morphine was used for pain control and he briefly +required a PCA pump. Once his neutropenia resolved, his +mucositis began to improve. However, the resultant increase in +secretions caused respiratory distress and hypoxia, requiring +ICU transfer for frequent deep suctioning and nebulizers. This +resolved rapidly and he returned to the floor. Mucositis +subsequently improved. + +3. Acute renal failure: Despite normal creatinine at 1.0, this +essentially doubled from low baseline of 0.4-0.7 and +BUN/creatinine 36. Likely in the setting of poor PO. He was +agressively hydrated with IVF and creatinine improved. + +4. Neutropenia: Secondary to chemotherapy. His ANC continued to +trend down during admission until he became severely +neutropenic. He was started on filgrastim and eventually his ANC +completely recovered. + +5. Thrombocytopenia: Also secondary to chemotherapy. Early in +the admission, he had some hematochezia, so was transfused plts +to keep his count over 30,000. + +6. Right UE DVT: Found on U/S in the setting of arm swelling. He +was started on enoxaparin. + +7. Colitis: Early on, paient complained of LLQ pain, associated +with hematochezia and then dark stools. He required 2 units RBCs +for this, but endoscopy could not be done due to his neutropenia +and thrombocytopenia. Stool studies were negative. CT abdomen +showed some bowel edema, but no diverticulitis. A CT chest done +a few days later noted some transverse colitis, although he was +asymptomatic. Metronidazole was empirically started and +continued for 5 days. Later on, in the setting of starting +enoxaparin for DVT, he had dark guaiac positive stools. GI was +consulted and felt bleeding was related to mucositis vs +colitis/inflammation in setting of anticoagulation and did not +feel there was indication for scope as an inpatient. His +hematocrit was stable prior to discharge. + +8. Esophageal cancer: On admission, he was day 9 status post +chemotherapy. He received no further treatments as an inpatient, +and he will follow up with his oncologist as an outpatient. + +9. Nutrition: Due to poor POs, PPN was started as there was not +enough access for TPN in the patient's chest port due to +antibiotics and IV fluids. Once his antibiotics were weaned, TPN +was initiated via his port. He also had an elevated INR that was +likely nutritional, and improved with vitamin K. + +Medications on Admission: +Emend 125mg day 1, 80mg days [**3-9**] +Xeloda 2g [**Hospital1 **] (days [**2-17**]) +Dexamethasone 4mg (days [**3-10**]) +Magic mouthwash tid prn +Lorazepam 0.5-1mg q4-6h prn +Megestrol 100mg/10ml susp daily +Metoclopramide 5mg tid +Metoprolol 100mg [**Hospital1 **] +Ondansetron 8mg q8h prn (? GI upset) +Gelclair tid +Oxycodone 5-10mg q4-6h prn +Prochlorperazine 10mg q6-8h prn +Ranitidine 150mg [**Hospital1 **] +Sucralfate 1g tid +Zolpidem 10mg hs prn + +Discharge Medications: +1. Flushes +Saline flush 10cc SASH and prn +heparin flush 10U/ml 5cc SASH and prn +Heparin 100U/ml 5cc deaccess port +2. Lidocaine HCl 2 % Solution Sig: Fifteen (15) ML Mucous +membrane TID (3 times a day) as needed. +Disp:*1 bottle* Refills:*0* +3. Lorazepam 0.5 mg Tablet Sig: 1-2 Tablets PO every 4-6 hours +as needed for anxiety or nausea. +4. Megestrol 400 mg/10 mL Suspension Sig: 100mg/10ml suspension +PO once a day. +5. Reglan 5 mg Tablet Sig: One (1) Tablet PO three times a day. + +6. Metoprolol Tartrate 50 mg Tablet Sig: Two (2) Tablet PO BID +(2 times a day). +7. ZOFRAN ODT 8 mg Tablet, Rapid Dissolve Sig: One (1) Tablet, +Rapid Dissolve PO every eight (8) hours as needed for nausea. +8. Oral Wound Care Products Gel in Packet Sig: One (1) ML +Mucous membrane TID (3 times a day) as needed. +9. Oxycodone 5 mg Tablet Sig: 1-2 Tablets PO every six (6) hours +as needed for pain. +10. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q6H (every 6 hours) as needed for nausea or vomit. +11. Sucralfate 1 gram Tablet Sig: One (1) Tablet PO three times +a day. +12. Ambien 10 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed for insomnia. +13. Enoxaparin 80 mg/0.8 mL Syringe Sig: One (1) syringe +Subcutaneous Q12H (every 12 hours). +Disp:*60 syringe* Refills:*0* +14. Cefpodoxime 100 mg Tablet Sig: Two (2) Tablet PO Q12H (every +12 hours) for 3 days. +Disp:*12 Tablet(s)* Refills:*0* +15. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q12H (every 12 hours). +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +16. Outpatient Lab Work +Please do weekly lab work and fax to [**First Name4 (NamePattern1) 553**] [**Last Name (NamePattern1) 18971**] [**Telephone/Fax (1) 55043**] to monito while on TPN. Check CBC, BUN, Cr, +electrolytes, albumin, LFTs. + + +Discharge Disposition: +Home With Service + +Facility: +Critical Care Systems + +Discharge Diagnosis: +Primary: +Chemotherapy induced diarrhea and mucositis +Pneumococcal bacteremia +Pneumonia +Deep venous thrombosis + +Secondary: +Esophageal cancer +Hypertension + + +Discharge Condition: +hemodynamically stable, afebrile, shortnes of breath and cough +improved + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] with dehydration, diarrhea, and +inflammation of the mucous membranes (mucositis). We gave you IV +fluids and started TPN, a form of nutrition given through the +veins. We also treated you with antibiotics for a bloodstream +infection and a pneumonia. We also started enoxaparin (Lovenox), +a blood thinner, due to a blood clot found in your arm veins. +Once your white blood cells recovered from your chemotherapy, +your mucositis continued to improve. We changed your ranitidine +to pantopraxole. + +Please take all medications as prescribed and go to all follow +up appointments. + +If you experience fevers, chills, vomiting, diarrhea, abdominal +pain, worsening mouth/throat pain, bloody stools, or any other +concerning symptoms, please seek medical attention or come to +the ER immediately. + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **]. Call [**Telephone/Fax (1) 6568**] for an +appointment in [**2-5**] weeks. + + + +",43,2145-05-28 14:38:00,2145-06-18 13:00:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOME HEALTH CARE,DEHYDRATION," +1. pneumococcal infection: while the patient was neutropenic, he +was febrile once. cultures were sent and he was started on +empiric cefepime. imaging suggested a lll pneumonia, and blood +cultures grew gpc, for which vancomycin was added. the gpc were +speciated as s. pneumoniae. tte showed no vegetations. no +further blood cultures were positive, and his antibiotics were +eventually narrowed to ceftriaxone alone for a 14 day course, +starting at the resolution of neutropenia. for easier dosing at +home, he was changed to cefpodoxine to finish course after +discharge. + +2. mucositis: unable to tolerate po and was resuscitated with +ivf. he was started on oral lidocaine and gelclairm as well as +oral fluconazole and nystatin for [**female first name (un) 564**]. he was later taken +off the fluconazole as it elevated his transaminases and changed +to micafungin. however, this was also stopped as it elevated his +bilirubin. iv morphine was used for pain control and he briefly +required a pca pump. once his neutropenia resolved, his +mucositis began to improve. however, the resultant increase in +secretions caused respiratory distress and hypoxia, requiring +icu transfer for frequent deep suctioning and nebulizers. this +resolved rapidly and he returned to the floor. mucositis +subsequently improved. + +3. acute renal failure: despite normal creatinine at 1.0, this +essentially doubled from low baseline of 0.4-0.7 and +bun/creatinine 36. likely in the setting of poor po. he was +agressively hydrated with ivf and creatinine improved. + +4. neutropenia: secondary to chemotherapy. his anc continued to +trend down during admission until he became severely +neutropenic. he was started on filgrastim and eventually his anc +completely recovered. + +5. thrombocytopenia: also secondary to chemotherapy. early in +the admission, he had some hematochezia, so was transfused plts +to keep his count over 30,000. + +6. right ue dvt: found on u/s in the setting of arm swelling. he +was started on enoxaparin. + +7. colitis: early on, paient complained of llq pain, associated +with hematochezia and then dark stools. he required 2 units rbcs +for this, but endoscopy could not be done due to his neutropenia +and thrombocytopenia. stool studies were negative. ct abdomen +showed some bowel edema, but no diverticulitis. a ct chest done +a few days later noted some transverse colitis, although he was +asymptomatic. metronidazole was empirically started and +continued for 5 days. later on, in the setting of starting +enoxaparin for dvt, he had dark guaiac positive stools. gi was +consulted and felt bleeding was related to mucositis vs +colitis/inflammation in setting of anticoagulation and did not +feel there was indication for scope as an inpatient. his +hematocrit was stable prior to discharge. + +8. esophageal cancer: on admission, he was day 9 status post +chemotherapy. he received no further treatments as an inpatient, +and he will follow up with his oncologist as an outpatient. + +9. nutrition: due to poor pos, ppn was started as there was not +enough access for tpn in the patients chest port due to +antibiotics and iv fluids. once his antibiotics were weaned, tpn +was initiated via his port. he also had an elevated inr that was +likely nutritional, and improved with vitamin k. + + ","PRIMARY: [Drug induced neutropenia] +SECONDARY: [Pneumonia, organism unspecified; Malignant neoplasm of liver, secondary; Secondary malignant neoplasm of lung; Candidiasis of mouth; Acute kidney failure, unspecified; ; Malignant neoplasm of other specified part of esophagus; Bacteremia; Dehydration; Anemia, unspecified; ; Atrial fibrillation; Other stomatitis and mucositis (ulcerative); Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Abnormal coagulation profile; Diarrhea; Pneumococcus infection in conditions classified elsewhere and of unspecified site; Unilateral paralysis of vocal cords or larynx, partial; Unspecified essential hypertension; Other and unspecified noninfectious gastroenteritis and colitis]" +30659,123675.0,13337,2146-03-26,13336,110439.0,2145-12-24,Discharge summary,"Admission Date: [**2145-12-20**] Discharge Date: [**2145-12-24**] + +Date of Birth: [**2087-12-9**] Sex: F + +Service: MEDICINE + +Allergies: +Zanaflex + +Attending:[**First Name3 (LF) 10293**] +Chief Complaint: +Chief complaint: Hypotension post-TIPS revision, after transfer +from OSH ([**Hospital3 17162**]) with shortness of breath, refractory +ascites + + +Major Surgical or Invasive Procedure: +TIPS revision, paracentesis x 2 + + +History of Present Illness: +History of Present Illness +Ms. [**Known lastname **] is a 58 yo woman with a history of HCV cirrhosis s/p +TIPS [**3-5**] who presents with increased abdominal distension. +. +She previously had refractory ascites in early [**2145**], and +underwent placement of TIPS for this reason. She was then doing +well and was without significant ascites on aldactone. Lasix was +added [**11-4**] for some edema. Subsequently her ascites continued to +worsen. She was getting therapeutic paracentesis with removal of +[**7-4**] L each time every two weeks. US [**11-18**] showed increased +velocity in the TIPS. +. +She was recently admitted to [**Hospital3 **] [**Date range (1) 40579**] with +increasing SOB, received 60 mg lasix underwent removal of 10 L +of ascitic fluid, with resolution of SOB. Creatinine at that +time on admission was 1.8. She had an ultrasound with Doppler +[**12-12**] showing increased flow in the TIPS. +. +She was doing well until [**12-18**] when she presented for routine +labs and was found to have renal failure beyond her baseline +(creatinine 2.0 elevated from recent b/l 1.5) and hyperkalemia +to 5.4 with peaked T waves. She received kayexalate, insulin, +bicarb, D50 and was admitted. Diuretics were held. Because of +concern for TIPS occlusion, she was transferred to [**Hospital1 18**] for +possible revision. +. +On acceptance to the medicine team, she complains of epigastric +pain, worse with lying and accompanied by a sour taste. She +denies fevers, chills, change in bowel movements or blood in BM +(baseline 4 BM/day on lactulose). Also no chest pain or +shortness of breath. No urinary symptoms. +. +Upon admission to [**Hospital1 18**], plan was to proceed with TIPS revision. + The day of admission to the MICU, she underwent TIPS revision +and had a 6L paracentesis. Intraoperatively you way hypotensive +to SBP 70s, treated with 1L 5% albumin and neo gtt without +complication. [**Name (NI) **], pt again became hypotensive to +the 70s, asymmptomatic and resolve with 50g 25% albumin and +500cc NS. In total in [**Name (NI) 13042**], pt received 1400cc NS, 800cc +Bicarb/D5W and 200cc of 25% albumin. EBL 147ml. +. +Upon transfer to MICU, patient confirms story as above. States +she's had some mild abdominal pain. +. + + +Past Medical History: +PAST MEDICAL HISTORY: +# ESLD secondary to HCV cirrhosis +- Hep C dxed [**2126**], unknown exposure: no hx transfusion, IVDU, +tatoo placed after hep C diagnosis +- genotype IA, treated with multiple courses of interferon +unsuccessfully +- bx [**2140**] stage 3-4 fibrosis +- hx encephalopathy, +- grade 3 varices banded [**3-5**]. No history of variceal bleeding. ++ history of hemorrhoidal bleeding. +- hx refractory ascites, s/p TIPS [**2145-3-19**], revised [**8-3**] after +presenting with recurrent ascites +- on transplant list +# Renal insufficiency, baseline creatinine 1.5 per OSH records +but previously has bumped to >2 +# Diastolic CHF +# Asthma +# Depression +# Anxiety +# GERD +# IDDM +# Seizure disorder +# Hypertension +# OSA +# Refractory nausea - controlled with reglan - ? gastroparesis +# s/p CCY +# h/o Asthma - stable +# Pancytopenia - related to ESLD +. + + +Social History: +From [**Male First Name (un) **] and visited recently. ? past h/o IVDU. Denies +tobacco, EtOH, or current recreational drug use. + + +Family History: +Family History: no family history of liver disease + +Physical Exam: +Admission PE: + +T 96.1 89, 100/58, 23, 99/RA +Gen: no apparent distress, appears well +HEENT/NECK: could not visualize JVP, supple, oropharynx clear, +sclera anicteric +Cor: regular, 2/6 systolic murmur heard best at the left upper +sternal border +Pulm: lungs clear bilaterally except fine bibasilar crackles +posteriorly +Abd: Distended, soft, nontender. + shifting dullness. No +rebound, no guarding. +Ext: trace pitting edema bilaterally, warm +Neuro: A&O x 3, appropriate, coherent historian, no asterixis. + +Pertinent Results: + +EKG [**12-20**]: Normal sinus rhythm at 87 bpm. Normal axis, normal +intervals. No evidence of ischemia. +. +Admission Labs: +[**2145-12-21**] 03:40AM BLOOD WBC-4.3 RBC-2.91* Hgb-10.3* Hct-28.5* +MCV-98 MCH-35.6* MCHC-36.2* RDW-14.1 Plt Ct-88* +[**2145-12-21**] 03:40AM BLOOD Neuts-72.3* Lymphs-15.6* Monos-8.4 +Eos-3.2 Baso-0.6 +[**2145-12-21**] 03:40AM BLOOD PT-14.6* PTT-32.8 INR(PT)-1.3* +[**2145-12-21**] 03:40AM BLOOD Plt Ct-88* +[**2145-12-21**] 03:40AM BLOOD Glucose-173* UreaN-35* Creat-1.7* Na-126* +K-4.2 Cl-95* HCO3-25 AnGap-10 +[**2145-12-21**] 03:40AM BLOOD ALT-24 AST-39 LD(LDH)-246 AlkPhos-393* +TotBili-4.9* +[**2145-12-21**] 03:40AM BLOOD Albumin-2.2* Calcium-7.5* Phos-3.8 Mg-2.1 +. +Labs prior to discharge: +[**2145-12-24**] 06:15AM BLOOD WBC-2.7* RBC-2.43* Hgb-9.1* Hct-23.8* +MCV-98 MCH-37.3* MCHC-38.0* RDW-14.5 Plt Ct-66* +[**2145-12-24**] 06:15AM BLOOD Glucose-125* UreaN-35* Creat-1.5* Na-129* +K-4.1 Cl-97 HCO3-25 AnGap-11 +[**2145-12-24**] 06:15AM BLOOD ALT-17 AST-33 AlkPhos-229* TotBili-5.4* +. +Micro: +[**2145-12-21**] URINE CULTURE (Final [**2145-12-22**]): + MIXED BACTERIAL FLORA ( >= 3 COLONY TYPES), CONSISTENT +WITH SKIN + AND/OR GENITAL CONTAMINATION. +. +Radographic studies: +. +LIVER OR GALLBLADDER US [**12-21**] (to evaluate TIPs) +IMPRESSION: +1. Patent TIPS with velocities of 100 to 180 cm/s. +2. There is a lack of wall-to-wall flow in the mid to distal +TIPS, suggestive +of neo-intimal hyperplasia. +3. Interval increase in the amount of ascites since the prior +exam. +4. Splenomegaly. + + +Brief Hospital Course: +A 57 yo woman with HCV cirrhosis s/p TIPS is transferred from +OSH with refractory ascites for consideration of TIPS revision. + +. +# Ascites: The patient had large ascites on exam but was not +uncomfortable. Last therapeutic tap had been [**12-13**]. Ultrasound +showed lack of wall-to-wall flow in the mid to distal TIPS, +suggestive of neo-intimal hyperplasia. Given the history of +apparent improvement in ascites after placement and subsequently +after revision of TIPS, she underwent TIPS revision with 10 mm +balloon and improved flow. Follow-up US two days later showed +patent tips. Paracentesis of 6 L was done at the time of +revision, and an additional 11.25 liters were taken off two days +later, with albumin replacement each time. Diuretics were held +for elevated creatinine. PPI was continued for reflux symptoms +likely secondary to ascites. +. +# Hypotension: Intraoperatively while under general anesthesia, +patient was hypotensive with SBP 70s. This continued in the +[**Month/Year (2) 13042**] post-operatively. Initial hypotension likely related to +anesthesia and fluid shift from large volume paracentesis. She +was transferred briefly to the MICU, where blood pressure +returned to baseline SBP 90s with IVF and albumin. +. +# Acute renal failure: Creatinine at OSH was increased from +baseline 1.5 to 2.0. On admission, creatinine was 1.7. Diuretics +were held. Urinary sodium was <10, consistent with prerenal vs +HRS. She was given albumin at the time of paracentesis, and +creatinine trended down to 1.5 prior to discharge. She was +discharged off all diuretics with plans for lab tests in 3 days +to monitor kidney function given that she had large volume +paracentesis on the day of discharge. +. +# UTI: She had had a recent E Coli treated with Bactrim at an +outside hospital. UA and cultures here were negative. +. +# Hyponatremia: Sodium was near baseline. She was asymptomatic. + +. +# DM: Lantus was continued at home dose; she was given regular +insulin as needed. +. +# Pancytopenia: Hematocrit and platelets were at baseline. +. +# Depression/Anxiety. Mirtazapine and trazadone were continued. +. +# Seizure disorder: Carbamazepine was continued. +. + +Medications on Admission: +- Potassium 20mEq PO daily +- Spironolactone 200mg PO daily +- Lactulose 30ml PO QID, titrated to [**2-28**] BM daily +- Rifaximin 400 mg PO TID +- Metoclopramide 10mg QACHS +- Lasix 40mg daily +- Clotrimazole +- Levaquin 250mg daily (for E. coli UTI, subseq R to levoflox) +- Protonix 40mg daily +- Mirtazapine 15mg PO HS +- Lantus 26 units SubQ +- Carbamazepine 200 mg QAM, 400 mg QPM +- Ibuprofen PRN pain +- Folic acid 1mg daily +- Dulcolax 1 tablet PO Q12H + + +Discharge Medications: +1. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO QID (4 +times a day). +2. Rifaximin 200 mg Tablet Sig: Two (2) Tablet PO TID (3 times a +day). +3. Metoclopramide 10 mg Tablet Sig: One (1) Tablet PO QID (4 +times a day) as needed for nausea. +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +5. Mirtazapine 15 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +6. Lantus +26 units qhs +7. Carbamazepine 200 mg Tablet Sig: One (1) Tablet PO QAM (once +a day (in the morning)). +8. Carbamazepine 200 mg Tablet Sig: Two (2) Tablet PO QPM (once +a day (in the evening)). +9. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +10. Clotrimazole 10 mg Troche Sig: One (1) Troche Mucous +membrane QID (4 times a day) as needed. +11. Outpatient Lab Work +Please do chemistry panel including creatinine, CBC, and LFTs. +Please fax results to: [**Telephone/Fax (1) 697**] ATTN: Dr. [**Last Name (STitle) 497**]. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +primary: cirrhosis +secondary: renal insufficiency, diastolic congestive heart +failure, type 2 diabetes + + +Discharge Condition: +stable + + +Discharge Instructions: +You were admitted to the hospital because you needed to have +your TIPS revised. You had the TIPS revised and fluid taken out +of your abdomen. + +The following medications were changed in the hospital: +spironolactone, lasix, levaquin, and potassium were stopped +. +Please have your labs checked next Monday, [**12-27**] with the +attached prescription. +. +Please call your doctor or return to the hospital if you have +chest pain or shortnes of breath, increasing abdominal girth, +fevers and chills, or other symptoms that are concerning to you. + + + +Followup Instructions: +Please have your labs checked on Monday, [**12-27**] with the +attached prescription. +. +You will need to have follow-up TIPS surveillance in [**7-4**] weeks. +Dr. [**Last Name (STitle) 497**] can arrange this. +. +You have an appointment for an ultrasound and then at the +[**Hospital 20871**] clinic: +ULTRASOUND Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2146-1-12**] 1:45 +TRANSPLANT [**Hospital 1389**] CLINIC Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2146-1-12**] 3:20 + + + +Completed by:[**2145-12-25**]",92,2145-12-20 23:09:00,2145-12-24 18:40:00,EMERGENCY,TRANSFER FROM HOSP/EXTRAM,HOME,REFRACTORY ASCITES," +a 57 yo woman with hcv cirrhosis s/p tips is transferred from +osh with refractory ascites for consideration of tips revision. + +. +# ascites: the patient had large ascites on exam but was not +uncomfortable. last therapeutic tap had been [**12-13**]. ultrasound +showed lack of wall-to-wall flow in the mid to distal tips, +suggestive of neo-intimal hyperplasia. given the history of +apparent improvement in ascites after placement and subsequently +after revision of tips, she underwent tips revision with 10 mm +balloon and improved flow. follow-up us two days later showed +patent tips. paracentesis of 6 l was done at the time of +revision, and an additional 11.25 liters were taken off two days +later, with albumin replacement each time. diuretics were held +for elevated creatinine. ppi was continued for reflux symptoms +likely secondary to ascites. +. +# hypotension: intraoperatively while under general anesthesia, +patient was hypotensive with sbp 70s. this continued in the +[**month/year (2) 13042**] post-operatively. initial hypotension likely related to +anesthesia and fluid shift from large volume paracentesis. she +was transferred briefly to the micu, where blood pressure +returned to baseline sbp 90s with ivf and albumin. +. +# acute renal failure: creatinine at osh was increased from +baseline 1.5 to 2.0. on admission, creatinine was 1.7. diuretics +were held. urinary sodium was <10, consistent with prerenal vs +hrs. she was given albumin at the time of paracentesis, and +creatinine trended down to 1.5 prior to discharge. she was +discharged off all diuretics with plans for lab tests in 3 days +to monitor kidney function given that she had large volume +paracentesis on the day of discharge. +. +# uti: she had had a recent e coli treated with bactrim at an +outside hospital. ua and cultures here were negative. +. +# hyponatremia: sodium was near baseline. she was asymptomatic. + +. +# dm: lantus was continued at home dose; she was given regular +insulin as needed. +. +# pancytopenia: hematocrit and platelets were at baseline. +. +# depression/anxiety. mirtazapine and trazadone were continued. +. +# seizure disorder: carbamazepine was continued. +. + + ","PRIMARY: [Other complications due to other vascular device, implant, and graft] +SECONDARY: [Acute kidney failure, unspecified; Other ascites; Diastolic heart failure, unspecified; ; Urinary tract infection, site not specified; Hyposmolality and/or hyponatremia; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Other iatrogenic hypotension; Cirrhosis of liver without mention of alcohol; Congestive heart failure, unspecified; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Chronic hepatitis C without mention of hepatic coma; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Hyperpotassemia; Asthma, unspecified type, unspecified; Dysthymic disorder; Esophageal reflux; Obstructive sleep apnea (adult)(pediatric); Epilepsy, unspecified, without mention of intractable epilepsy; ; Long-term (current) use of insulin]" +31692,116133.0,19351,2186-07-02,19350,174449.0,2186-04-13,Discharge summary,"Admission Date: [**2186-3-10**] Discharge Date: [**2186-4-13**] + +Date of Birth: [**2130-11-30**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1666**] +Chief Complaint: +Shortness of breath + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +Pt is a 55 yo man w/ h/o end-stage sarcoid dx on home O2 (3L NC) +no longer on xplant list, on home O2, who p/w SOB, f/c x 5 +days. Pt was in his USOH until 5 days ago when noted increased +SOB, dry cough. Called PCPs office on [**3-8**], who directed him to +go to ED, but pt waited as is having financial problems at home +and wanted to wait to work out some things before coming to ED. +Pt had self-titrated up O2 to 4L. Also states felt like he had a +fever o/n, but did not take temp. Today pt was seen at home by +OT who noted that he had decreased O2 sats to 85-90% on 4L O2. +OT called PCPs office who instructed them to call ambulance. +Pt initially presented to [**Hospital3 **] where +initial vitals noted to be T 98.8, HR 81, BP 132/68, RR 18, O2 +91% 4L NC. Labs notable for slightly elevated WBC at 10.4. CXR +there demonstrated ?new infiltrate, although difficult to assess +given underlying lung dx. Pt was given rocephin 1gm x 1, azithro +500mg x 1, and transferred to [**Hospital1 18**]. +In ED initial vitals T 97.4, HR 104, BP 115/82, RR 20, O2 91% 4L +NC. Pt admitted for further management. +Currently pt c/o continued SOB, cough, no other complaints at +this time. + + +Past Medical History: +1. Hepatitis C, diagnosed as part of the lung transplant workup + +at the [**Hospital1 756**]. He is followed by Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] in GI. He +is hepatitis B core surface antibody positive and surface +antigen +negative. In addition, he has hepatitis C antibody plus type 2b + +with a viral load in [**8-/2185**], of 5.5 million. He had grade 2 +fibrosis on [**2184-4-28**]. He is not thought to be a candidate +currently for interferon treatment given his sarcoidosis. He has + +transaminitis. +2. Sarcoidosis. He is followed by Dr. [**Last Name (STitle) 2168**]. The patient has +been obtaining PFTs from Dr. [**Last Name (STitle) **], and he is currently on +azathioprine and prednisone with prophylaxis Bactrim. +3. Sleep apnea. +4. Erectile dysfunction. +5. Emotional lability and anxiety. +6. Status post mandible fracture [**8-20**]. +7. Status post multiple rib and clavicle fractures over the past + +year secondary to fall. +8. Spinal stenosis: diagnosed on MRI and is followed by Dr. [**First Name8 (NamePattern2) **] +[**Last Name (NamePattern1) 363**], [**First Name3 (LF) **] orthopedic physician at the [**Hospital1 18**]. The diagnosis was +established as part of a workup for progressive lower leg +weakness, which led to multiple falls and currently an inability +to ambulate. +9. Shingles in [**12/2184**] on the right side of the face with +residual neuropathic pain. + + +Social History: +Lives in an apartment in [**Location (un) 1459**] with his 27 yo daughter who +is s/p traumatic brain injury in a motor vehicle accident. Has +another daughter from whom he is estranged. Recently divorced +from his wife of 33 years who he says did ""not want to take care +of him."" Patient is a former food salesman, selling restaurant +supplies to pizzerias. Has been unemployed for about a year, no +longer on unemployment. Recently obtained some disability +benefits. Reports a 10 pack year smoking history, but quit 20 +years ago. Reports no history of ethanol use or IV drug use. Pt +had previous admission in which he was on high doses of +methadone and benzodiazepenes that were verified by PCP to be +prescribed by an outpatient physician to treat his pain from +spinal stenosis; pt believed to withdraw from both on previous +admissions. + +Family History: +Non contributory of pulmonary disease. + +Physical Exam: +Admission +Vitals - T 97.9, HR 97, BP 121/70, RR 25, O2 86% --> 94% 4L NC +Gen - awake, alert, eating [**Location (un) 6002**], tachypnic slightly, +speaking in full sentences +CVS - RRR no noted m/r/g +Lungs - mild decreased BS diffusely but overall fairly good air +movement w/ no noted crackles, + mild wheezing +Abd - soft, NT/ND +Ext - trace LE edema b/l +. +Discharge +Vitals - T 97.9, HR 97, BP 126/86, RR 18, O2 98%6L with facemask +mist supplementation +Gen - awake, alert, comfortable, speaking in full sentences +CVS - RRR no noted m/r/g +Lungs - mild decreased BS diffusely but overall fairly good air +movement w/ no noted crackles, + mild expiratory wheezes at +bases, no increased work of breathing +Abd - soft, NT/ND +Ext - trace LE edema b/l, + mild right forearm edema + + +Pertinent Results: +CXR [**2186-3-11**]:Extensive pulmonary fibrosis and architectural +distortion, presumably due to the provided history of sarcoid +although basilar predominance is atypical. No findings to +suggest an acute superimposed pneumonia, but subtle infection +could be easily obscured by the chronic lung disease. +. +CXR [**2186-4-6**]: +Today's study demonstrates fracture displacement of the right +seventh rib laterally, other lower fractures were demonstrated +along the lateral chest wall on the 9:27 a.m. film. Severe +pulmonary fibrosis and marked emphysema are longstanding. There +is no evidence of acute pulmonary changes though subtle findings +would be missed. No appreciable pleural effusion is seen. Heart +size is normal. No pneumothorax. +. +CT Chest [**2186-3-14**] +1. No evidence of pneumonia or other acute cardiopulmonary +process. +2. Chronic severe pulmonary fibrosis, could be end- stage +sarcoidosis. +Chronic pulmonary hypertension. +3. Previous right upper lobe infection resolved. +4. Possible small right upper lobe mycetoma. +5. New left lower lobe 3.5 mm lung nodule warrants [**5-25**] month CT +followup. +. +CT abd: +1. Bilateral rectus sheath hematomas as described above. Small +amount of blood in the fat-containing right inguinal hernia. +2. No evidence of retroperitoneal hematoma. +3. Changes in the lung bases, incompletely evaluated, are +consistent with the patient's history of sarcoid. +4. Healing bilateral rib fractures. +5. Abdominal aortic ectasia as above up to 2.8 cm. +6. Nonobstructing left nephrolithiasis. +. +CT Chest [**2186-4-6**]: +1. Small PE of segmental/subsegmental right upper lobe branch. +This was communicated by Dr. [**First Name8 (NamePattern2) **] [**Name (STitle) 24949**] with Dr. [**First Name8 (NamePattern2) **] +[**Last Name (NamePattern1) 3766**] by telephone in the AM on [**2186-4-10**]. +2. New minimally displaced fracture of the lateral right ninth +rib. Multiple additional bilateral healing rib fractures. +3. Healing left distal clavicle fracture. +3. Resolution of right upper lobe pneumonia. +4. Chronic severe pulmonary fibrosis in the setting of +sarcoidosis. +. +LE U/S:No evidence of DVT in either extremity. +. +CBC +[**2186-3-11**] 05:15AM BLOOD WBC-9.2 RBC-3.74* Hgb-13.2* Hct-39.3* +MCV-105* MCH-35.4* MCHC-33.6 RDW-15.3 Plt Ct-259 +[**2186-3-13**] 04:40AM BLOOD WBC-10.6 RBC-3.70* Hgb-13.0* Hct-39.3* +MCV-106* MCH-35.3* MCHC-33.2 RDW-15.9* Plt Ct-294 +[**2186-3-14**] 04:40AM BLOOD WBC-12.0* RBC-3.53* Hgb-12.4* Hct-36.9* +MCV-105* MCH-35.1* MCHC-33.6 RDW-15.4 Plt Ct-269 +[**2186-3-19**] 05:11AM BLOOD WBC-10.1 RBC-3.72* Hgb-13.1* Hct-39.9* +MCV-107* MCH-35.1* MCHC-32.7 RDW-16.1* Plt Ct-232 +[**2186-3-21**] 04:40AM BLOOD WBC-11.3* RBC-3.71* Hgb-13.1* Hct-39.9* +MCV-108* MCH-35.4* MCHC-32.9 RDW-16.2* Plt Ct-298 +[**2186-3-23**] 07:30AM BLOOD WBC-11.0 RBC-3.56* Hgb-12.4* Hct-38.6* +MCV-108* MCH-34.9* MCHC-32.3 RDW-16.2* Plt Ct-297 +[**2186-3-25**] 06:22AM BLOOD WBC-10.8 RBC-3.40* Hgb-12.0* Hct-36.4* +MCV-107* MCH-35.4* MCHC-33.1 RDW-16.3* Plt Ct-282 +[**2186-3-28**] 03:58PM BLOOD Hct-32.0* +[**2186-3-31**] 07:55AM BLOOD WBC-10.6 RBC-2.86* Hgb-10.0* Hct-31.1* +MCV-109* MCH-35.1* MCHC-32.2 RDW-16.9* Plt Ct-361 +[**2186-4-2**] 06:03AM BLOOD WBC-11.1* RBC-2.91* Hgb-10.3* Hct-32.3* +MCV-111* MCH-35.2* MCHC-31.8 RDW-17.1* Plt Ct-320 +[**2186-4-5**] 05:54AM BLOOD WBC-15.2* RBC-3.26* Hgb-11.6* Hct-36.2* +MCV-111* MCH-35.5* MCHC-32.0 RDW-16.5* Plt Ct-367 +[**2186-4-9**] 05:42AM BLOOD WBC-9.6 RBC-3.10* Hgb-11.1* Hct-33.9* +MCV-109* MCH-35.8* MCHC-32.8 RDW-16.2* Plt Ct-259 +[**2186-4-10**] 04:08AM BLOOD WBC-8.6 RBC-3.18* Hgb-11.2* Hct-34.7* +MCV-109* MCH-35.1* MCHC-32.1 RDW-16.3* Plt Ct-277 +[**2186-4-11**] 05:35AM BLOOD WBC-7.7 RBC-3.18* Hgb-11.2* Hct-34.7* +MCV-109* MCH-35.3* MCHC-32.4 RDW-16.3* Plt Ct-290 +. +Chem 7 +[**2186-3-11**] 05:15AM BLOOD Glucose-243* UreaN-16 Creat-0.5 Na-138 +K-4.9 Cl-101 HCO3-28 AnGap-14 +[**2186-3-13**] 04:40AM BLOOD Glucose-222* UreaN-20 Creat-0.5 Na-141 +K-3.9 Cl-105 HCO3-27 AnGap-13 +[**2186-3-15**] 05:31AM BLOOD Glucose-125* UreaN-18 Creat-0.5 Na-143 +K-3.9 Cl-104 HCO3-29 AnGap-14 +[**2186-3-19**] 05:11AM BLOOD Glucose-154* UreaN-27* Creat-0.5 Na-144 +K-4.3 Cl-105 HCO3-30 AnGap-13 +[**2186-3-23**] 07:30AM BLOOD Glucose-103 UreaN-23* Creat-0.6 Na-140 +K-4.3 Cl-100 HCO3-32 AnGap-12 +[**2186-3-26**] 05:39AM BLOOD Glucose-142* UreaN-29* Creat-0.6 Na-143 +K-4.6 Cl-105 HCO3-25 AnGap-18 +[**2186-3-28**] 06:42AM BLOOD Glucose-128* UreaN-23* Creat-0.4* Na-143 +K-4.2 Cl-105 HCO3-34* AnGap-8 +[**2186-3-30**] 05:05AM BLOOD Glucose-120* UreaN-22* Creat-0.5 Na-140 +K-4.6 Cl-101 HCO3-32 AnGap-12 +[**2186-4-1**] 06:06AM BLOOD Glucose-98 UreaN-17 Creat-0.5 Na-142 +K-4.2 Cl-104 HCO3-36* AnGap-6* +[**2186-4-3**] 05:17AM BLOOD Glucose-186* UreaN-25* Creat-0.5 Na-143 +K-4.2 Cl-104 HCO3-35* AnGap-8 +[**2186-4-9**] 05:42AM BLOOD Glucose-139* UreaN-24* Creat-0.6 Na-144 +K-3.9 Cl-102 HCO3-36* AnGap-10 +[**2186-4-10**] 04:08AM BLOOD Glucose-139* UreaN-20 Creat-0.5 Na-145 +K-3.8 Cl-106 HCO3-35* AnGap-8 +[**2186-4-11**] 05:35AM BLOOD Glucose-111* UreaN-20 Creat-0.5 Na-147* +K-3.9 Cl-106 HCO3-36* AnGap-9 +. +MISC +[**2186-3-11**] 05:15AM BLOOD ALT-131* AST-140* LD(LDH)-342* +[**2186-3-19**] 05:11AM BLOOD ALT-96* AST-113* AlkPhos-104 TotBili-0.5 +[**2186-4-8**] 03:52AM BLOOD CK-MB-NotDone cTropnT-0.08* +[**2186-4-8**] 11:50AM BLOOD CK-MB-NotDone cTropnT-0.15* +[**2186-4-8**] 05:55PM BLOOD Type-ART pO2-79* pCO2-54* pH-7.44 +calTCO2-38* Base XS-10 +[**2186-4-8**] 05:55PM BLOOD O2 Sat-93 + +Brief Hospital Course: +#SHORTNESS OF BREATH / VIRAL BRONCHITIS / SARCOIDOSIS / ANXIETY +Mr. [**Known lastname 52653**] was admitted with worsening SOB and lower oxygen +saturations. This was not felt to be a flare of sarcoidosis but +more likely a viral infection on top of severe underlying lung +disease caused by sarcoid. A pulmonary consultation was +obtained. Prednisone was increased to 60mg PO daily in addition +to his azathioprine 150mg once daily. His oxygen flow was +increased to four liters, and later to 5-6 liters. He briefly +went to the MICU on [**2186-4-7**] for worsening tachypnea; he remained +on his baseline 6L NC with shovel mask mist support. After +returning to the floor and again becoming tachypneic, he +underwent CTA which showed as small subsegmental PE. LENI's were +negative for DVT. As the patient had had recent bleeding with +rectus sheath hematomas, anticoagulation was not started.His +outpt pulmonologist was made aware and agreed with holding off +on anticoagulation. At discharge, he was restarted on lower dose +sc heparin 5000 [**Hospital1 **] (down from TID). He will be followed +closely as an outpt with Dr. [**Last Name (STitle) **]. At discharge he was 97% +on 6L NC and shovel mask mist support, slightly tachypnic. Per +Dr.[**Last Name (STitle) 18309**], transtracheal oxygen catheter has been discussed to +improve oxygen delivery. He was evaluated by throracic surgery +during his inpt stay but a decision was defered as the surgeon +was out of town. The cardiothoracic surgery clinic will call the +patient with an appointment to follow up in clinic for +evaluation. +. +#PSEUDOMONAS PNEUMONIA +He stabilized after initial presentation but intermittently +became tachypneic from his viral bronchitis, but later developed +much more productive cough with phlegm. Sputum culture was +obtained which was notable for multidrug-resistant pseudomonas. +CT scan showed interval developement of new RUL consolidation. +He was treated with meropenem for 14 days. Subsequent CT showed +interval resolution. +. +#SEVERE ANXIETY +He has severe anxiety related to advanced illness and is quite +fearful of death, and this exacerbated respiratory symptoms. A +palliative care consultation was obtained and the patient wsa +tried on sublingual morphine with an increase in his anxiolytic +medications. He personally was not yet ready for hospice. In +terms of psychopharmacology, the patient was started on +risperidone 1mg PO BID, and his duloxetine was increased to 90mg +PO daily. SL Morphine aided in comfort. +. +#RIB FRACTURES / OSTEOPOROSIS: +THe patient had several old rib fractures, but also developed a +new acute rib fracture during this admission. This is due to +chronic steroid use and coughing. A vitamin D level was normal +in [**11-19**]. A repeat Vit D level is pending. This value should be +followed up on and Vit D supplements started if low. The patient +may also need bisphosphonates although the long-term benefits +are doubtful given his poor prognosis. +. +#RECTUS SHEALTH HEMATOMA +The patient developed a moderate sized rectus shealth hematoma +during this admission with 8 point hematocrit drop. This was +felt to be in part to coughing while on subcutaneous heparin +injections. Heparin sc was discontinued. His HCT stabilized +without intervention. Heparin at a lower dose of 5000 [**Hospital1 **] was +restarted. If the patient has any sign of bleeding or worsening +abd bruising, discontinue heparin and please use pneumoboots. +. +#FALL +The patient fell on [**2186-4-6**] while toileting. He did not hit his +head and had no LOC. +New rib fracture and rectus sheath hematoma were not attributed +to this fall. +. +#SPINAL STENOSIS +The patient was continued on long and short acting morphine for +pain control. +His MS contin was increased to 45/15/45 mg three times per day +respectively. +He had sublingual morphine and percocet on PRN basis. +. +#PAIN MEDICATION ISSUES +The patient was seen by nursing to be saving pain medication for +his daughter. [**Name (NI) **] was directly observed taking all medications +subsequently. There were no subsequent concerns regarding pain +medication. +. +# MENTAL STATUS +The patient is typically fully oriented, though he had frequent +periods where he was unsure of surroundings. He typically became +quite paranoid at night and felt that most night nurses were +playing tricks on him. He was started on risperidone 1mg PO BID +with PRN haldol for agitation. + +Medications on Admission: +Albuterol PRN , Azathioprine 150mg daily Klonipin 0.5mg TID PRN + +Cymbalta 60mg daily Advair 500/50 INH [**Hospital1 **] Remeron 15mg qhs +Morphine SR 30mg TID Omeprazole 20mg daily Percocet q6hr PRN +Prednisone 40mg daily Simvastatin 20mg daily Spiriva 18mcg INH +daily Trazadone 50mg qhs PRN ASA 325mg daily colace +senna thiamine 100mg daily tylenol PRN + + +Discharge Medications: +1. Albuterol Sulfate 2.5 mg/3 mL Solution for Nebulization Sig: +One (1) neb Inhalation Q6H (every 6 hours). +2. Azathioprine 50 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +3. Duloxetine 30 mg Capsule, Delayed Release(E.C.) Sig: Three +(3) Capsule, Delayed Release(E.C.) PO DAILY (Daily). +4. Mirtazapine 15 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +5. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +6. Prednisone 20 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +7. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +8. Tiotropium Bromide 18 mcg Capsule, w/Inhalation Device Sig: +One (1) Cap Inhalation DAILY (Daily). +9. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +10. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day). +11. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +12. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +13. Trimethoprim-Sulfamethoxazole 160-800 mg Tablet Sig: One (1) +Tablet PO QMWF (). +14. Fluticasone-Salmeterol 500-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +15. Trazodone 50 mg Tablet Sig: 0.5 Tablet PO HS (at bedtime) as +needed. +16. Clonazepam 1 mg Tablet Sig: One (1) Tablet PO TID (3 times a +day). +17. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +18. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +19. Morphine 15 mg Tablet Sustained Release Sig: One (1) Tablet +Sustained Release PO q 1:00pm as needed. +20. Morphine 15 mg Tablet Sustained Release Sig: Three (3) +Tablet Sustained Release PO QAM (once a day (in the morning)). +21. Morphine 15 mg Tablet Sustained Release Sig: Three (3) +Tablet Sustained Release PO QPM (once a day (in the evening)). +22. Morphine Concentrate 20 mg/mL Solution Sig: 0.5-0.75 mL PO +Q3H (every 3 hours) as needed. +23. Lorazepam 1 mg Tablet Sig: One (1) Tablet PO Q3H PRN (). +24. Oxycodone-Acetaminophen 5-325 mg Tablet Sig: One (1) Tablet +PO Q4H (every 4 hours) as needed for pain. +25. Nystatin 100,000 unit/mL Suspension Sig: Five (5) ML PO QID +(4 times a day) as needed. +26. Risperidone 1 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +27. Haloperidol 0.5 mg Tablet Sig: Two (2) Tablet PO BID (2 +times a day) as needed. +28. Insulin +12 units NPH qAM, 6 units NPH qPM +Regular Insulin Sliding scale coverage (see attached scale) +29. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO Q8H +(every 8 hours) as needed. +30. Sodium Chloride 0.65 % Aerosol, Spray Sig: Two (2) Spray +Nasal QID (4 times a day) as needed. +31. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection [**Hospital1 **] (2 times a day). + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 672**] Hospital + +Discharge Diagnosis: +Primary: +- Acute exacerbation of COPD +- Hospital acquired pneumonia +- Rectus sheath hematoma +- End stage pulmonary sarcoid + +Secondary: +- Chronic immunosuppression +- Obstructive sleep apnea +- Left III nerve palsy +- Anxiety; depression; paranoia +- Traumatic mandibular, rib, clavicle fractures +- Spinal stenosis; frequent falls +- Chronic pain +- Zoster +- Hepatitis C + + +Discharge Condition: +Stable. On 6L NC. afebrile. + + +Discharge Instructions: +You were admitted with shortness of breath and thought to have a +viral bronchitis on top of your sarcoidosis. You had a new +pneumonia and were treated with IV antibiotics: 14 day course of +meropenem completed. You were continued on a higher dose of +predisone as well as your current dose of azathioprine. +. +You had a large abdominal (rectus sheath) hematoma that will +improve over time. +. +Your medications were changed. +Your prednisone was increased as above. +Your pain medications have changed; please review your NEW +medication list and adjust your home meds as needed. +. +If you develop worsening shortness of breath, low oxygen +saturations on your current level of home oxygen, fevers or +chills, please return to the hospital. + +Followup Instructions: +New left lower lobe 3.5 mm lung nodule warrants [**5-25**] month CT +followup. +. +Please make an appointment with Dr. [**Last Name (STitle) **], your outpt +psychiatrist ([**Telephone/Fax (1) 52654**]) to be seen in [**12-14**] weeks. + +Provider: [**Last Name (NamePattern4) **]. [**First Name (STitle) 1112**]/DR. [**Last Name (STitle) **] Phone:[**Telephone/Fax (1) 612**] +Date/Time:[**2186-5-1**] 2:00 +Provider: [**Name10 (NameIs) 1571**] FUNCTION LAB Phone:[**Telephone/Fax (1) 609**] +Date/Time:[**2186-5-1**] 1:00 +Provider: [**Name10 (NameIs) 1570**],INTERPRET W/LAB NO CHECK-IN [**Name10 (NameIs) 1570**] INTEPRETATION +BILLING Date/Time:[**2186-5-1**] 1:00 + + + [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1672**] MD, [**MD Number(3) 1673**] + +",80,2186-03-10 21:06:00,2186-04-13 14:34:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,PNEUMONIA," +#shortness of breath / viral bronchitis / sarcoidosis / anxiety +mr. [**known lastname 52653**] was admitted with worsening sob and lower oxygen +saturations. this was not felt to be a flare of sarcoidosis but +more likely a viral infection on top of severe underlying lung +disease caused by sarcoid. a pulmonary consultation was +obtained. prednisone was increased to 60mg po daily in addition +to his azathioprine 150mg once daily. his oxygen flow was +increased to four liters, and later to 5-6 liters. he briefly +went to the micu on [**2186-4-7**] for worsening tachypnea; he remained +on his baseline 6l nc with shovel mask mist support. after +returning to the floor and again becoming tachypneic, he +underwent cta which showed as small subsegmental pe. lenis were +negative for dvt. as the patient had had recent bleeding with +rectus sheath hematomas, anticoagulation was not started.his +outpt pulmonologist was made aware and agreed with holding off +on anticoagulation. at discharge, he was restarted on lower dose +sc heparin 5000 [**hospital1 **] (down from tid). he will be followed +closely as an outpt with dr. [**last name (stitle) **]. at discharge he was 97% +on 6l nc and shovel mask mist support, slightly tachypnic. per +dr.[**last name (stitle) 18309**], transtracheal oxygen catheter has been discussed to +improve oxygen delivery. he was evaluated by throracic surgery +during his inpt stay but a decision was defered as the surgeon +was out of town. the cardiothoracic surgery clinic will call the +patient with an appointment to follow up in clinic for +evaluation. +. +#pseudomonas pneumonia +he stabilized after initial presentation but intermittently +became tachypneic from his viral bronchitis, but later developed +much more productive cough with phlegm. sputum culture was +obtained which was notable for multidrug-resistant pseudomonas. +ct scan showed interval developement of new rul consolidation. +he was treated with meropenem for 14 days. subsequent ct showed +interval resolution. +. +#severe anxiety +he has severe anxiety related to advanced illness and is quite +fearful of death, and this exacerbated respiratory symptoms. a +palliative care consultation was obtained and the patient wsa +tried on sublingual morphine with an increase in his anxiolytic +medications. he personally was not yet ready for hospice. in +terms of psychopharmacology, the patient was started on +risperidone 1mg po bid, and his duloxetine was increased to 90mg +po daily. sl morphine aided in comfort. +. +#rib fractures / osteoporosis: +the patient had several old rib fractures, but also developed a +new acute rib fracture during this admission. this is due to +chronic steroid use and coughing. a vitamin d level was normal +in [**11-19**]. a repeat vit d level is pending. this value should be +followed up on and vit d supplements started if low. the patient +may also need bisphosphonates although the long-term benefits +are doubtful given his poor prognosis. +. +#rectus shealth hematoma +the patient developed a moderate sized rectus shealth hematoma +during this admission with 8 point hematocrit drop. this was +felt to be in part to coughing while on subcutaneous heparin +injections. heparin sc was discontinued. his hct stabilized +without intervention. heparin at a lower dose of 5000 [**hospital1 **] was +restarted. if the patient has any sign of bleeding or worsening +abd bruising, discontinue heparin and please use pneumoboots. +. +#fall +the patient fell on [**2186-4-6**] while toileting. he did not hit his +head and had no loc. +new rib fracture and rectus sheath hematoma were not attributed +to this fall. +. +#spinal stenosis +the patient was continued on long and short acting morphine for +pain control. +his ms contin was increased to 45/15/45 mg three times per day +respectively. +he had sublingual morphine and percocet on prn basis. +. +#pain medication issues +the patient was seen by nursing to be saving pain medication for +his daughter. [**name (ni) **] was directly observed taking all medications +subsequently. there were no subsequent concerns regarding pain +medication. +. +# mental status +the patient is typically fully oriented, though he had frequent +periods where he was unsure of surroundings. he typically became +quite paranoid at night and felt that most night nurses were +playing tricks on him. he was started on risperidone 1mg po bid +with prn haldol for agitation. + + ","PRIMARY: [Obstructive chronic bronchitis with acute bronchitis] +SECONDARY: [Pneumonia due to Pseudomonas; Acute posthemorrhagic anemia; Pneumonia, organism unspecified; Acidosis; Other pulmonary embolism and infarction; Pathologic fracture of other specified site; Sarcoidosis; Lung involvement in other diseases classified elsewhere; Obstructive sleep apnea (adult)(pediatric); Unspecified viral hepatitis C without hepatic coma; Other dependence on machines, supplemental oxygen; Third or oculomotor nerve palsy, partial; Dysthymic disorder; Spinal stenosis, unspecified region; Constipation, unspecified; Encounter for palliative care; Other disorders of muscle, ligament, and fascia; Other chronic pulmonary heart diseases; Hypoxemia; Other chronic pain; Other abnormal glucose; Adrenal cortical steroids causing adverse effects in therapeutic use; Osteoporosis, unspecified]" +31969,151726.0,21685,2110-05-14,21684,116681.0,2109-12-27,Discharge summary,"Admission Date: [**2109-12-23**] Discharge Date: [**2109-12-27**] + +Date of Birth: [**2033-9-7**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 4616**] +Chief Complaint: +Malaise and fever + +Major Surgical or Invasive Procedure: +central line placement + + +History of Present Illness: +This is a 76 yo F w/h/o pancreatic cancer s/p whipple and s/p +external beam XRT concurrent with xeloda, currently being +treated with Gemcitabine weekly w/last chemo [**2109-12-18**]. At home, +pt had persistant malaise, light-headedness, and LE myalgias +which normally last ~2 days after chemotherapy but this time +persisted. She also noted 2 days of fever to max of 101.5, +along with rhinorrhea, sore throat, and epistaxis which had been +bothering her for ~1 week. She normally checks her BP at home, +but for the past few days her automated BP cuff had been saying +""unreadable"" when she tried to measure it. Pt's baseline BP is +reportedly in 120s, but in the past after chemo it would dip to +the 100s. With chemo, pt reports decreased apetite, and her +daughter notes that she has lost 2 lbs in the past week. Also +of note, pt has had chronic diarrhea for ~6 months, but after +starting Lomotil, Immodium, and Viokase 8 (pancreatic enzyme +replacment) her #of BMs has decreased from 4 to 2 per day. On +the morning of admission, the fever and light-headedness +prompted the pt's family to call her oncology NP, who told them +to call EMS. On EMS arrival BP was 100/50. +. +On ROS Pt denies SOB, chest pain, cough, headache, sinus +pressure, neck stiffness, visual changes, nausea, vommiting, +worsening diarrhea, melena, hematochezia, dysuria, and +hematuria. +. +In the [**Hospital1 18**] ED SBP was initially in the low 100s, and +temp=100.6. 2L IVF where given, and despite the administraton +of fluid SBP fell to the 80s. Right IJ placed (MAP 58 CVP 10) +and pt was started on norepinephrine gtt and Vanco/Ceftaz were +administered. Pt was never tachycardic or hypoxic. Lactate +1.0, HCT 25. Guiac (-) brown stool. CXR was clear, and U/A +clear. + +Past Medical History: +-pancreatic cancer diagnosed at [**Hospital6 1597**] [**4-16**], s/p +Whipple [**2109-5-10**]. S/p Cyber Knife and external beam XRT concurrent +with xeloda. Currently getting Gemcitabine weekly w/last chemo +[**2109-12-18**]. +-CBD obstruction with stent +- s/p PE on coumadin +- h/o uterine sarcoma: stage Ib, grade III endometrial +carcinoma: s/p TAH-BSO [**9-13**], +- Aortic stenosis +- Hypertension +- Type 2 diabetes +- Glaucoma +- herpes in L eye + +Social History: +No smoking, No alcohol, no drug use. +Lives alone in home in [**Location (un) 583**], but son or daughter stays with +her +at night. Independent when well. Children have been staying +with her because they are concerned about her. Dtr. is HCP. + + +Family History: +daughter with endometrial carcinoma, sister with liver cancer, +father with lung cancer, no fam h/o blood clots + +Physical Exam: +VS: Temp: 97.3 BP: 102/42 HR:71 RR:16 O2sat 98 RA CVP 11 +GEN: pleasant, comfortable, NAD +HEENT: R PERRL, L Pupil Surgical, EOMI, anicteric, MMM, op +without lesions +NECK: no supraclavicular or cervical lymphadenopathy, no jvd, no +carotid bruits, no thyromegaly or thyroid nodules +RESP: CTA b/l with good air movement throughout +CV: RR, S1 and S2 wnl, no blowing [**2-13**] creshendo/decreshendo M +heard throughout precorium but best at RUSB +ABD: nd, +b/s, soft, nt, no masses or hepatosplenomegaly +EXT: no c/c/e, warm, good pulses +SKIN: no rashes/no jaundice +NEURO: AAOx3. Cn II-XII intact. 5/5 strength throughout. No +sensory deficits to light touch appreciated. No clonus. +RECTAL (in ED): Guiac (-) brown stool + +Pertinent Results: +CBC: +[**2109-12-23**] +WBC-4.4 RBC-2.66* Hgb-9.2* Hct-24.5* MCV-92 MCH-34.5* MCHC-37.6* +RDW-13.5 Plt Ct-93* +[**2109-12-23**] +WBC-3.9* RBC-1.94*# Hgb-6.6*# Hct-18.7* MCV-97 MCH-34.0* +MCHC-35.1* RDW-14.0 Plt Ct-75* +[**2109-12-27**] +WBC-3.7* RBC-2.63* Hgb-8.7* Hct-24.5* MCV-93 MCH-33.2* +MCHC-35.6* RDW-13.9 Plt Ct-88* +. +COAGS: +[**2109-12-23**] +PT-36.1* PTT-51.4* INR(PT)-3.8* +[**2109-12-27**] +PT-18.9* PTT-30.4 INR(PT)-1.7* +. +CHEM: +[**2109-12-23**] +Glucose-154* UreaN-37* Creat-1.6* Na-131* K-3.9 Cl-97 HCO3-18* +AnGap-20 +[**2109-12-27**] +Glucose-153* UreaN-14 Creat-0.9 Na-133 K-3.8 Cl-105 HCO3-22 +AnGap-10 +. +ANEMIA LABS: +[**2109-12-26**] +Iron-36 calTIBC-139* Folate-9.2 Ferritn-GREATER TH TRF-107* +. +URINE: +[**2109-12-23**] +Color-Straw Appear-Clear Sp [**Last Name (un) **]-1.006 Blood-NEG Nitrite-NEG +Protein-NEG Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG +pH-5.0 Leuks-SM RBC-0 WBC-[**5-20**]* Bacteri-MOD Yeast-MOD Epi-[**2-12**] +. +[**12-23**] BCx: negative +[**12-23**] UCx: YEAST. 10,000-100,000 ORGANISMS/ML.. +[**12-24**] UCx: YEAST. ~6OOO/ML. +[**12-26**] Stool: FECES NEGATIVE FOR C. DIFFICILE TOXIN BY EIA. +. +[**2109-12-23**] CXR +AP UPRIGHT CHEST: The tip of a new right internal jugular +central venous catheter terminates in the distal SVC. The +cardiac, mediastinal and hilar contours appear stable. The lungs +are clear. The pulmonary vasculature is normal. There is no +pleural effusion or pneumothorax. The visualized osseous +structures appear unremarkable. +IMPRESSION: +1. Standard position of the right IJ central venous catheter, +terminating in the distal SVC. +2. No acute cardiopulmonary process. +. +[**12-23**] EKG +Sinus rhythm. Compared to the previous tracing of [**2109-7-3**] R wave +progression is improved. + +Brief Hospital Course: +A/P: 76 yo F w/ h/o pancreatic cancer, currently receiving +chemotherapy who presented with fever and hypotension requiring +pressors: pt initially admitted to ICU for r/o sepsis. Pt with +mildly positive UA and no other clear source of infection, . +. +# Hypotension: on presentation had hypotension that was not +responisve to fluids. She was started on levophed in the ED and +after 12 hours in ICU levofed was successfully weaned and BP was +stable. Hypotension was most likely [**1-11**] decreased PO intake in +the setting of chronic diarrhea and outpatient antihypertensive +medications. Sepsis was considered since pt continued to have +hypotension despite CVP of 12. Before D/C from the ICU BP was +stable for 24 hours and pt was afebrile. Pt had initially been +started on cipro and flagyl for weakly positive UA and empiric +coverage for possible intra-abdominal process. These antibiotics +were stopped shortly thereafter due to lack of data c/w +infectious etiology (see below). Remained afebrile and BP stable +off of antibiotics. On the Onc floor, her BPs were stable off of +her antihypertensive regimen. We were able to restart her +atenolol but ACE was held on discharge, to be restarted as +tolerated as an outpatient. +. +# Pancreatic Cancer: Chemo side effects likely contributed to +diarrhea. Onc plans were held and deferred to outpatient +oncology team. +. +# Diarrhea: Pt was continued on home viokase for pancreatic +enzyme replacement. She also takes immodium and lomotil for +chronic diarrhea. A Ciff assay was negative. +. +# Pancytopenia: All cell lines were depressed -- likely +pancytopenia [**1-11**] chemotherapy. No signs of bleeding aside from +epistaxis in the setting of supratherapeutic INR. Pt was +transfused a total of 2 units pRBCs with appropriate HCT +response. Also received 1 unit platelets (see below). +. +# Fever: Fever resolved by the time of call out from the ICU. Pt +was afebrile on floor. Culture data did not reveal a clear +source. Likely that fever on presentation was due to a viral +URI, given history of rhinorrhea and sore throat. Because Cx +data was negative cipro and flagyl were discontinued on the day +that she was called out from the MICU. Abx not resumed on floor. +. +# Hx of PE: treated with coumadin at home. INR was +supratherapeutic throughout time in the ICU. On the day of +call-out she was having epistaxis. Likely that quinolone +administration was prolonging the INR. Given FFP before transfer +to the floor. Had some persistent bleeding on floor. Was +transfused 1 unit of platelets (nadir value was 40 with +bleeding), with resolution of epistaxis. Resumed coumadin +regimen prior to d/c, but was still not therapeutic prior to +discharge. Therefore, given enoxaparin daily injections with +plan for outpt INR checks. +. +# Myalgias: most likley [**1-11**] chemo. Gave tylenol PRN. +. +# DM: On glyburide at home, which was held and HISS was given. +Restarted on discharge. +. +# Code: Full + +Medications on Admission: +Atenolol 50 mg PO DAILY +Enalapril 10 mg PO DAILY +Warfarin 2.5 mg TTSS and 3 mg MWF +Glyburide 2.5 mg PO BID +Ativan 0.5-1 mg QDay PRN +Compazine 10 mg TID PRN +Lomotil 2.5 mg PO BID +Viokase 8 1-2 tabs QIDAC +Vit B12 +Immodium + + +Discharge Medications: +1. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO 4X/WEEK +([**Doctor First Name **],TU,TH,SA). +2. Warfarin 1 mg Tablet Sig: Three (3) Tablet PO 3X/WEEK +(MO,WE,FR). +3. Cyanocobalamin 100 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Atenolol 50 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +5. Prochlorperazine Maleate 10 mg Tablet Sig: One (1) Tablet PO +Q8H (every 8 hours) as needed for nausea. +6. Lorazepam 0.5 mg Tablet Sig: 1-2 Tablets PO DAILY (Daily) as +needed for Anxiety. +7. Amylase-Lipase-Protease 30,000-8,000- 30,000 unit Tablet Sig: +1-2 Tablets PO QIDAC (). +8. GlyBURIDE 2.5 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +9. Imodium A-D 2 mg Tablet Sig: One (1) Tablet PO as directed as +needed for diarrhea. +10. Enoxaparin 100 mg/mL Syringe Sig: One Hundred (100) mg +Subcutaneous once a day: until otherwise instructed by MD. +[**Last Name (Titles) **]:*5 syringes* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] Home Health Care + +Discharge Diagnosis: +Primary: +Hypotension +. +Secondary: +# pancreatic cancer diagnosed at [**Hospital6 1597**] [**4-16**], s/p +Whipple [**2109-5-10**]. S/p Cyber Knife and external beam XRT concurrent +with xeloda. Currently getting Gemcitabine weekly w/last chemo +[**2109-12-18**]. +# CBD obstruction with stent +# s/p PE on coumadin +# h/o uterine sarcoma: stage Ib, grade III endometrial +carcinoma: s/p TAH-BSO [**9-13**], +# Aortic stenosis +# Hypertension +# Type 2 diabetes +# Glaucoma +# herpes in L eye + +Discharge Condition: +stable, normotensive, ambulating independently + + +Discharge Instructions: +You were admitted to the hospital with fevers and low blood +pressure. You were briefly in our ICU because you needed +medicine to suppport your blood pressure. However, you were +quickly able to come off that medicine. We checked for any signs +of infection but there were none. +. +We are restarting one of your blood pressure medicines, +atenolol. However, given your recent low blood pressures, you +should not take you enalapril until instructed by your PCP or +oncologist. +. +You will be going home with physical therapy and a visiting +nurse to check your blood counts as well as the level of couadin +in your blood. In the meantime, you will need to take an +injection of Lovenox once per day to make sure your blood is +thin enough. +. +Please make sure to take all your medicines as prescribed. +Please keep all your followup appointments. If you experience +any fevers/chills, lightheadedness, or other symptoms which +concern you, please call your doctor or go to the ED. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Name8 (MD) **], MD Phone:[**Telephone/Fax (1) 22**] Date/Time:[**2110-1-8**] +1:00 +Provider: [**First Name8 (NamePattern2) **] [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 22**] +Date/Time:[**2110-1-8**] 1:00 +Provider: [**Name10 (NameIs) **] FELT, RN Phone:[**Telephone/Fax (1) 22**] +Date/Time:[**2110-1-8**] 2:00 +. +Please see your PCP: [**Name10 (NameIs) **],[**First Name3 (LF) 251**] R [**Telephone/Fax (1) 57021**], in the next 2 +weeks. + + + +",138,2109-12-23 17:22:00,2109-12-27 17:53:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,HYPOTENSION," +a/p: 76 yo f w/ h/o pancreatic cancer, currently receiving +chemotherapy who presented with fever and hypotension requiring +pressors: pt initially admitted to icu for r/o sepsis. pt with +mildly positive ua and no other clear source of infection, . +. +# hypotension: on presentation had hypotension that was not +responisve to fluids. she was started on levophed in the ed and +after 12 hours in icu levofed was successfully weaned and bp was +stable. hypotension was most likely [**1-11**] decreased po intake in +the setting of chronic diarrhea and outpatient antihypertensive +medications. sepsis was considered since pt continued to have +hypotension despite cvp of 12. before d/c from the icu bp was +stable for 24 hours and pt was afebrile. pt had initially been +started on cipro and flagyl for weakly positive ua and empiric +coverage for possible intra-abdominal process. these antibiotics +were stopped shortly thereafter due to lack of data c/w +infectious etiology (see below). remained afebrile and bp stable +off of antibiotics. on the onc floor, her bps were stable off of +her antihypertensive regimen. we were able to restart her +atenolol but ace was held on discharge, to be restarted as +tolerated as an outpatient. +. +# pancreatic cancer: chemo side effects likely contributed to +diarrhea. onc plans were held and deferred to outpatient +oncology team. +. +# diarrhea: pt was continued on home viokase for pancreatic +enzyme replacement. she also takes immodium and lomotil for +chronic diarrhea. a ciff assay was negative. +. +# pancytopenia: all cell lines were depressed -- likely +pancytopenia [**1-11**] chemotherapy. no signs of bleeding aside from +epistaxis in the setting of supratherapeutic inr. pt was +transfused a total of 2 units prbcs with appropriate hct +response. also received 1 unit platelets (see below). +. +# fever: fever resolved by the time of call out from the icu. pt +was afebrile on floor. culture data did not reveal a clear +source. likely that fever on presentation was due to a viral +uri, given history of rhinorrhea and sore throat. because cx +data was negative cipro and flagyl were discontinued on the day +that she was called out from the micu. abx not resumed on floor. +. +# hx of pe: treated with coumadin at home. inr was +supratherapeutic throughout time in the icu. on the day of +call-out she was having epistaxis. likely that quinolone +administration was prolonging the inr. given ffp before transfer +to the floor. had some persistent bleeding on floor. was +transfused 1 unit of platelets (nadir value was 40 with +bleeding), with resolution of epistaxis. resumed coumadin +regimen prior to d/c, but was still not therapeutic prior to +discharge. therefore, given enoxaparin daily injections with +plan for outpt inr checks. +. +# myalgias: most likley [**1-11**] chemo. gave tylenol prn. +. +# dm: on glyburide at home, which was held and hiss was given. +restarted on discharge. +. +# code: full + + ","PRIMARY: [Acute kidney failure, unspecified] +SECONDARY: [Other specified aplastic anemias; Hyposmolality and/or hyponatremia; Acidosis; Hypovolemia; Personal history of venous thrombosis and embolism; Personal history of malignant neoplasm of other gastrointestinal tract; Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Epistaxis; Unspecified essential hypertension; Aortic valve disorders; Long-term (current) use of anticoagulants]" +32247,113222.0,15732,2122-09-29,15731,180961.0,2122-09-17,Discharge summary,"Admission Date: [**2122-9-11**] Discharge Date: [**2122-9-17**] + +Date of Birth: [**2059-1-8**] Sex: F + +Service: SURGERY + +Allergies: +Percocet / Motrin / Nsaids / Aspirin / Dilantin + +Attending:[**First Name3 (LF) 668**] +Chief Complaint: +Abdominal pain + +Major Surgical or Invasive Procedure: +[**2122-9-13**]: negative exploratory laparotomy + + +History of Present Illness: +62yo F w/ a PMH of ESRD on HD s/p failed kidney transplant, +DVT (associated w/ HD cath), and HTN who presents to the ED +today +with right lower quadrant abdominal pain and hypotension. She +was +nauseated last night and had vomiting x 1. Nonbloody, +nonbilious. +Last bowel movement was 2 days ago. Not constipated. No +diarrhea. No fever chillls or night sweats. She has had the +abdominal pain for weeks. Food makes the pain better. She has +not eaten today so the pain has gotten worse over the last +couple +of days. + + +Past Medical History: +1. Diabetes mellitus.- unclear hx, not on medication, nl [**Name (NI) **] +2. End-stage renal disease secondary to diabetes mellitus s/p +failed dual kidney transplant +3. Hemodialysis. +4. Hypertension. +5. Hyperlipidemia. +6. Thrombosis of bilateral IVJ (catheter placement)-- DVT +associated with HD catheter RUE on anticoagulation +7. SVC syndrome [**1-13**], s/p thrombectomy, on anticoagulation, +hospitalization complicated by obturator hematoma and required +intubation, PEG and Trach with VAP, and questionable seizure +8. Currently, in hemodialysis. +9. Osteoarthritis. +10. Arthritis of the left knee at age nine, treated with ACTH +resulting in secondary [**Location (un) **]. +11. rheumatic fever as child +12. Afib with RVR + +Past Surgical History: +1. Kidney transplant in [**2119**]. +2. Left arm AV fistula for dialysis. +3. Removal of remnant of AV fistula, left arm. +4. Catheter placement for hemodialysis. +5. Low back surgery (unspecified) + +Social History: +-lives with her nephew [**Name (NI) **], but does not know his number +-Brother is HCP +-[**Name (NI) 1139**]: 10pkyr [**Name2 (NI) 1818**], recently quit but states that she has +restarted and smoking 5 cigs per day +-denies etoh/illicits + + +Family History: +Mother and sister with diabetes mellitus. +Kidney failure in mother, sister + + +Physical Exam: +Vital signs: T 96.0 HR 110 BP 96/46 RR 16 O2sat 95% on RA +General: No acute distress +Cardiovascular: regular rate and rhythm, systolic murmur +Pulmonary: clear to ausculation bilaterally +Abdomen: Soft, nondisteded, tender to palpation in the +suprapubic +area and in the right lower quadrant, no guarding +Rectal exam: guiac negative, no gross blood, no hemorrhoids on +exam + + +Pertinent Results: +On Admission: [**2122-9-10**] +WBC-9.2 RBC-4.33 Hgb-14.1 Hct-42.7 MCV-99* MCH-32.5* MCHC-33.0 +RDW-15.4 Plt Ct-451* +PT-22.3* INR(PT)-2.1* +Glucose-199* UreaN-47* Creat-9.7*# Na-139 K-4.0 Cl-92* HCO3-26 +AnGap-25* +ALT-9 AST-12 AlkPhos-45 TotBili-0.3 +Calcium-9.7 Phos-7.0* Mg-2.3 +On Discharge [**2122-9-17**] +WBC-6.2 RBC-2.94* Hgb-9.5* Hct-29.9* MCV-102* MCH-32.4* +MCHC-31.9 RDW-14.5 Plt Ct-317 +PT-31.2* PTT-40.3* INR(PT)-3.2* +K-3.6 + +Brief Hospital Course: +63 y/o female s/p failed kidney transplant in past and recent +admission for She now returns with abdominal pain. +A CT scan of the abdomen demonstrated portal venous air and +pneumatosis involving the right colon. She was taken to the OR +with Dr [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **]. In summary, upon inspection of the +peritoneal cavity there was no free fluid. No fibrinous exudate +and no foul smell. There was virtually no adhesions in the +abdominal cavity. The +terminal ileum was identified. This was run retrograde to the +ligament Treitz without evidence of small bowel pathology. There +was no significant pathology involving the right colon. No +evidence of the pneumatosis or gangrenous changes were +identified. The colon was run from the right colon to the distal +sigmoid. Multiple diverticula are noted throughout the +left-sided colon as well +as 1 or 2 small diverticula in the small bowel, but again no +evidence of perforation, no gangrenous changes, no pneumatosis +was identified. There was no fibrinous exudate. +In the PACU following the case she became increasingly +somnolent, BP hypertensive, she was reintubated and transferred +to the ICU. She was started on IV Levaquin. +She was extubated on POD 1 and remained stable thereafter. +HD via tunneled line with last HD on [**9-16**] with 2 Liters removed. +She was kept on telemetry and had an episode of tachycardia +which resolved without additional beta blockade. +Every day she became more alert and more able to participate +with PT, so she was able to be discharged home with full +services for OT/PT, nursing and social work +Coumadin restarting [**9-19**] with PT/INR to be drawn and results +faxed to [**First Name8 (NamePattern2) 5969**] [**Last Name (NamePattern1) 5970**] by the VNA. She will then resume +monitoring with Dr[**Name (NI) 4849**] at [**Location (un) **] as she was +pre-hospitalization. Next HD Saturday [**9-20**]. Stable per renal. + + +Medications on Admission: +ATORVASTATIN [LIPITOR] - (Prescribed by Other Provider) - 20 mg +Tablet - 1 Tablet(s) by mouth once a day +B COMPLEX-VITAMIN C-FOLIC ACID [RENAL CAPS] - (Prescribed by +Other Provider) - 1 mg Capsule - 1 Capsule(s) by mouth once a +day +CINACALCET [SENSIPAR] - (Prescribed by Other Provider; Dose +adjustment - no new Rx) - 90 mg Tablet - 1 Tablet(s) by mouth +once a day +DARBEPOETIN ALFA IN POLYSORBAT [ARANESP (POLYSORBATE)] - +(Prescribed by Other Provider) - 40 mcg/mL Solution - once per +week weekly +LISINOPRIL - (Prescribed by Other Provider) - 5 mg Tablet - 1 +Tablet(s) by mouth daily +METOPROLOL TARTRATE - (Prescribed by Other Provider) - 100 mg +Tablet - 1 Tablet by mouth daily +SERTRALINE [ZOLOFT] - (Prescribed by Other Provider) - 100 mg +Tablet - 1 Tablet(s) by mouth hs +WARFARIN - (Prescribed by Other Provider) - 2 mg Tablet - 4 +Tablet(s) by mouth once a day + + +Discharge Medications: +1. Metoprolol Succinate 100 mg Tablet Sustained Release 24 hr +[**Month/Year (2) **]: One (1) Tablet Sustained Release 24 hr PO once a day. +2. Atorvastatin 20 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. + +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Month/Year (2) **]: One (1) Cap +PO DAILY (Daily). +4. Cinacalcet 90 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. +5. Sertraline 100 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. +6. Lisinopril 5 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO DAILY (Daily). + +7. Acetaminophen-Codeine 300-30 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO +Q4H (every 4 hours) as needed for pain. +Disp:*20 Tablet(s)* Refills:*0* +8. Warfarin 1 mg Tablet [**Month/Year (2) **]: Two (2) Tablet PO once a day: +Please restart [**2122-9-18**]. Do NOT dose on [**9-17**]. +9. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO twice a +day: Started with previous admission, scripts given at last +discharge. +Disp:*90 Tablet(s)* Refills:*2* +10. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO following +HD. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Abdominal pain s/p ex-lap for potential small bowel obstruction, +which was negative + + +Discharge Condition: +Good + + +Discharge Instructions: +Please call the transplant clinic at [**Telephone/Fax (1) 673**] for fever > +101, chills, nausea, vomiting, diarrhea, increased abdominal +pain, inability to take or keep down medications. +Monitor incision for redness, drainage or bleeding. Incison may +be left open to air. +Continue hemodialysis via left tunneled dialysis line. Next HD +[**9-19**] at [**Location (un) **] +Continue food, fluid and medications per renal recommendations +No showering with dialysis catheter +Dr[**Name (NI) **] at [**Location (un) **] dialysis will continue to follow +PT/INR, dialysis unit aware + +Followup Instructions: +[**Last Name (LF) **],[**First Name3 (LF) **] TRANSPLANT SOCIAL WORK Date/Time:[**2122-9-25**] 1:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time: [**2122-9-25**] 2 PM +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2122-10-16**] 2:00 +[**Month/Day/Year 1220**]. [**Name5 (PTitle) 540**] & [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 44**] Date/Time:[**2122-11-10**] +4:30 + + + +Completed by:[**2122-9-17**]",12,2122-09-11 22:13:00,2122-09-17 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,BENIGN PNEUMATOSIS," +63 y/o female s/p failed kidney transplant in past and recent +admission for she now returns with abdominal pain. +a ct scan of the abdomen demonstrated portal venous air and +pneumatosis involving the right colon. she was taken to the or +with dr [**first name8 (namepattern2) **] [**last name (namepattern1) **]. in summary, upon inspection of the +peritoneal cavity there was no free fluid. no fibrinous exudate +and no foul smell. there was virtually no adhesions in the +abdominal cavity. the +terminal ileum was identified. this was run retrograde to the +ligament treitz without evidence of small bowel pathology. there +was no significant pathology involving the right colon. no +evidence of the pneumatosis or gangrenous changes were +identified. the colon was run from the right colon to the distal +sigmoid. multiple diverticula are noted throughout the +left-sided colon as well +as 1 or 2 small diverticula in the small bowel, but again no +evidence of perforation, no gangrenous changes, no pneumatosis +was identified. there was no fibrinous exudate. +in the pacu following the case she became increasingly +somnolent, bp hypertensive, she was reintubated and transferred +to the icu. she was started on iv levaquin. +she was extubated on pod 1 and remained stable thereafter. +hd via tunneled line with last hd on [**9-16**] with 2 liters removed. +she was kept on telemetry and had an episode of tachycardia +which resolved without additional beta blockade. +every day she became more alert and more able to participate +with pt, so she was able to be discharged home with full +services for ot/pt, nursing and social work +coumadin restarting [**9-19**] with pt/inr to be drawn and results +faxed to [**first name8 (namepattern2) 5969**] [**last name (namepattern1) 5970**] by the vna. she will then resume +monitoring with dr[**name (ni) 4849**] at [**location (un) **] as she was +pre-hospitalization. next hd saturday [**9-20**]. stable per renal. + + + ","PRIMARY: [Other specified disorders of intestine] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; ; Acidosis; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Atrial fibrillation; Hypotension, unspecified; ]" +32247,127308.0,15733,2122-12-31,15732,113222.0,2122-09-29,Discharge summary,"Admission Date: [**2122-9-22**] Discharge Date: [**2122-9-29**] + +Date of Birth: [**2059-1-8**] Sex: F + +Service: MEDICINE + +Allergies: +Percocet / Motrin / Nsaids / Aspirin / Dilantin / Ativan + +Attending:[**First Name3 (LF) 1973**] +Chief Complaint: +Altered mental status + +Major Surgical or Invasive Procedure: +Intubation + +History of Present Illness: +63F with multiple medical problems and multiple admissions for +altered mental status presenting with abdominal pain and altered +mental status. Ms. [**Known lastname **] [**Last Name (Titles) 1834**] exploratory laparotomy on +[**2122-9-11**] and was found to have benign cecal pneumatosis. The +patient presents now for progressive confusion and decreased +mental acuity. The family is not available to discuss their +concerns and the patient complains of unchanged abdominal pain. + + +In the ED her vitals were 98.2 99 123/39 17 99%RA. FSG was 86 on +arrival. Exam showed A+O x 1. Labs were c/w ESRD, with AG +acidosis, but no hyperkalemia. Neurology was consulted given the +AMS, and felt it was due to a toxic-metabolic encephalopathy and +not a central insult or seizure. CXR was unrevealing except for +LLL atelectasis. No urine able to be obtained but blood cultures +were sent. A CT head was negative. A CT abdomen and pelvis was +obtained which showed no acute process or abscess, but a small +hematoma/stranding in the anterior subcutaneous tissues and +likely also left rectus, c/w recent surgery. Her HR did increase +to the 140s in the ED, responded to IV labetolol, but pressure +dropped. This responded to IVF. She was given 250mg of +levetiracetam and admitted to medicine for further workup of AMS +and correction of electrolytes. + +Past Medical History: +PMH: +1. Multiple admission with altered MS recently ([**10-13**]) - with +recent extensive neurological workup revealing multifocal +etiology likely due to HD fluid/electrolyte shifts, ? uremia +prior to HD, also component of vascular dementia. Started on +[**Month/Year (2) 13401**] [**9-14**]. +2. Diabetes mellitus. +3 End-stage renal disease secondary to diabetes mellitus s/p +failed dual extended-criteria donor renal transplant (BK virus +nephropathy) +4. Hemodialysis. +5. Hypertension. +6. Hyperlipidemia. +7. Thrombosis of bilateral IVJ (catheter placement)-- DVT +associated with HD catheter RUE on anticoagulation (Coumadin) +--balloon angioplasty performed [**1-13**]. +8. Osteoarthritis. +9. PER OMR NOTES (?) - Arthritis of the left knee at age nine, +treated with ACTH resulting in secondary [**Location (un) **]. She was +diagnosed with rheumatic fever. +10. h/o Trach and PEG [**1-13**] (reversed [**2-13**]). +11. h/o L tension pneumothorax [**2-7**] intubation +. +Past Surgical History: +1. Kidney transplant in [**2119**] b/l in RLQ +2. Left arm AV fistula for dialysis. +3. Removal of remnant of AV fistula, left arm. +4. Catheter placement for hemodialysis. +5. Low back surgery (unspecified) + + +Social History: +The patient smokes half a pack of cigarettes a day for the last +20 years. She does not drink alcohol or has ever experienced +with recreational drugs, has no tattoos. The patient has had +transfusions in [**2119**] and [**2120**]. The patient is a homemaker. The +patient has experienced economic problems lately. +. + + + +Family History: +Family History: From prior d/c summary +Mother and sister with diabetic mellitus. +Kidney failure in mother, sister + +Physical Exam: +On admission to ICU +PE: intubated, sedated, NAD +VS: T 98.0 BP 157/64--> 80s/40s with propofol HR 96 RR 12, 100% +AC 100% 500 x 20 5 +General: intubated, sedated +HEENT: tongue is swollen and protruding from her mouth, blood +visible around ET tube, lips swollen. L pupil briskly reactive +to light from 3 mm --> 1 mm; R pupil is sluggish, 3 mm --> 2 mm. +anicteric . +NECK: no JVD, supple +CV: +s1s2 RRR 2/6 systolic murmur, no R/G. +L.sided tunnel cath + +no erythema, C/D/I, currently accessed/receiveing IVF. +PULM: CTA B/L +ABD: +bs, midline inscision c/d/i, staples in place, soft, ND. +EXT: no C/C/edema 2+pulses b/l +NEURO: intubated/sedated. moves all 4. + + +Pertinent Results: +Admission labs: +[**2122-9-21**] 04:00PM PLT COUNT-415 +[**2122-9-21**] 04:00PM NEUTS-67.4 LYMPHS-20.1 MONOS-9.8 EOS-2.6 +BASOS-0.1 +[**2122-9-21**] 04:00PM WBC-8.3 RBC-2.72* HGB-9.1* HCT-27.7* MCV-102* +MCH-33.3* MCHC-32.7 RDW-16.1* +[**2122-9-21**] 04:00PM ACETMNPHN-NEG bnzodzpn-NEG barbitrt-NEG +[**2122-9-21**] 04:00PM CALCIUM-9.7 PHOSPHATE-8.0*# MAGNESIUM-2.5 +[**2122-9-21**] 04:00PM GLUCOSE-58* UREA N-49* CREAT-13.8*# +SODIUM-136 POTASSIUM-6.8* CHLORIDE-99 TOTAL CO2-21* ANION +GAP-23* +[**2122-9-21**] 04:09PM LACTATE-1.4 K+-4.6 +[**2122-9-21**] 05:24PM PT-18.3* PTT-29.2 INR(PT)-1.7* +[**2122-9-22**] 06:50AM PLT COUNT-421 +[**2122-9-22**] 06:50AM WBC-8.5 RBC-2.83* HGB-9.2* HCT-29.4* MCV-104* +MCH-32.7* MCHC-31.4 RDW-15.5 + +[**9-21**] CT ABD/PELVIS: no acute process, diverticulosis, extensive +atherosclerotic changes, left anterior subcutaneous tissue +stranding with hematoma-post surgical, extensive collateral +circulation, suggestive of an upper extremity thrombus. + +CT HEAD (noncontrast) [**9-21**]: no acute intracranial process, +multiple lacunar infarcts, chronic small vessel ischemic disease +(unchanged) + +EEG: This is an abnormal 24-hour video EEG telemetry in the +waking and sleeping states due to the occasional left +mid-temporal sharp +waves suggestive of a potential focus of epileptogenesis. In +addition, +there were bursts of generalized delta frequency slowing +suggestive of +midline subcortical dysfunction. Nonetheless, there were no +electrographic seizures and no pushbutton activations noted. + +[**2122-9-29**] 01:30PM BLOOD WBC-6.4 RBC-3.28* Hgb-10.9* Hct-33.7* +MCV-103* MCH-33.3* MCHC-32.4 RDW-16.6* Plt Ct-470* +[**2122-9-29**] 01:30PM BLOOD Plt Ct-470* +[**2122-9-29**] 01:30PM BLOOD PT-27.6* PTT-131.8* INR(PT)-2.8* +[**2122-9-29**] 01:30PM BLOOD Glucose-134* UreaN-36* Creat-9.5*# Na-136 +K-3.7 Cl-97 HCO3-26 AnGap-17 +[**2122-9-29**] 01:30PM BLOOD Calcium-8.6 Phos-5.8* Mg-2.2 + +Brief Hospital Course: +1. Altered mental status/seizure/intubation: most likely +etiology is multiple missed hemodialysis sessions/uremia. It is +possible the Tylenol with codeine she was taking for post +operative pain control contributed. The morning following +admission she had an episode of decreased responsiveness, clonic +jerks, lip smacking and hand automatisms. She was evaluated by +neurology and was given Ativan and Depakote for complex partial +seizure. Approximately 1 hour after this she became unresponsive +and her tongue was swollen. She was intubated for airway +protection due to angioedema. Her mental status normalized +(thought to be related to post-ictal state and medications), EEG +was negative for status epilepticus, head CT and toxicology +screens were negative. The patient required daily dialysis from +[**Date range (3) 45315**] and her mental status normalized and was stable +for several days at discharge. + +2. Angioedema/respiratory failure: Her tongue was noted to be +swollen prior to the administration of Depakote during +suctioning prior to intubation. The angioedema seemed to +correlate with the Ativan administration. There is a report of +angioedema in the past, attributed to Dilantin--but she received +Ativan at that time as well. She was treated for 24 hours with +steroids with remarkable improvement. Her lisinopril was also +discontinued. Her intubation was for airway protection in the +setting of altered mental status and angioedema. She had +persistent apneic episodes on the ventilator and never developed +a cuff leak. She has presumed tracheal stenosis from prior +tracheostomy. She was successfully extubated in the presence of +anesthesia on [**2122-9-25**]. It is recommended she have an outpatient +sleep study to evaluate for obstructive sleep apnea as well as +an outpatient allergy evaluation. + +3. Seizures: The patient suffered a partial complex seizure on +the morning after admission. The neurology team followed the +patient throughout her admission. +She was initially loaded with depakote, however, this was then +tapered off and her [**Date Range 13401**] dosing was increased to 500 mg twice +daily and an additional dose following hemodialysis. She will +follow up with Neurology as an outpatient. + +4. ESRD on HD: She missed two outpatient HD sessions prior to +admission. She was dialyzed daily in the MICU from [**Date range (1) 45316**] +then returned to her scheduled of T/T/Saturday. + +5. Atrial fibrillation: Rate control with metoprolol. She had a +single episode of RVR in the ED prior to admission which +responded to labetalol, otherwise, she was effectively rate +controlled. Her INR was subtherapeutic at admission, but was +therapeutic at discharge. Her INR will need to be followed in +rehabilitation and outpatient monitoring set up prior to +discharge home. + +6. Abdominal Pain: likely post operative, waxed and waned on +this admission. At the time of discharge, the pain was +controlled by Tylenol. Her staples were removed by the surgical +team during this hospitalization. She had increased discharge +from her abdominal wound noted on [**2122-9-28**]. The surgery team +evaluated and felt the wound was healing well and there was no +evidence of a wound infection. They recommended daily dry +dressing changes. + +7. Benign Hypertension: continued on amlodipine and metoprolol. +Lisinopril discontinued in the setting of angioedema and not +restarted. The amlodipine was started in its place. Her blood +pressure ranged 110-140s/50-70s prior to discharge. + +8. Disposition: the patient was discharged to a rehabilitation +facility. She will benefit from a home safety evaluation and +visiting nurses to evaluate medication understanding/compliance. +She requires INR monitoring. As an outpatient, she should have +an allergy evaluation for the recurrent angioedema as well as a +sleep study to evaluate sleep apnea. + + +Medications on Admission: +MEDS: +1. Metoprolol Succinate 100 mg Tablet Sustained Release 24 hr +[**Date Range **]: One (1) Tablet Sustained Release 24 hr PO once a day. +2. Atorvastatin 20 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. + +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Date Range **]: One (1) Cap + +PO DAILY (Daily). +4. Cinacalcet 90 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +5. Sertraline 100 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +6. Lisinopril 5 mg Tablet [**Date Range **]: One (1) Tablet PO DAILY (Daily). + +7. Acetaminophen-Codeine 300-30 mg Tablet [**Date Range **]: One (1) Tablet PO + +Q4H (every 4 hours) as needed for pain. +Disp:*20 Tablet(s)* Refills:*0* +8. Warfarin 1 mg Tablet [**Date Range **]: Two (2) Tablet PO once a day: +Please restart [**2122-9-18**]. Do NOT dose on [**9-17**]. +9. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO twice a +day: Started with previous admission +10. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO following + +HD. + + +Discharge Medications: +1. Metoprolol Tartrate 50 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO TID +(3 times a day). +2. Atorvastatin 20 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO DAILY +(Daily). +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Month/Year (2) **]: One (1) Cap +PO DAILY (Daily). +4. Cinacalcet 30 mg Tablet [**Month/Year (2) **]: Three (3) Tablet PO DAILY +(Daily). +5. Sertraline 100 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO DAILY +(Daily). +6. Warfarin 1 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO DAILY (Daily). +7. Levetiracetam 500 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO BID (2 +times a day). +8. Levetiracetam 500 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO HD +PROTOCOL (HD Protochol). +9. Amlodipine 5 mg Tablet [**Month/Year (2) **]: Two (2) Tablet PO DAILY (Daily). + +10. Acetaminophen 500 mg Tablet [**Month/Year (2) **]: 1-2 Tablets PO Q6H (every 6 +hours) as needed: not to exceed 4 grams/24 hours. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 1186**] - [**Location (un) 538**] + +Discharge Diagnosis: +Primary: +Altered mental status +Uremia +Angioedema +Respiratory failure +Complex partial seizure + +Secondary +Hypertension +End stage renal disease on hemodialysis +Atrial fibrillation +Seizure Disorder +Failed renal transplant X 2 +Hyperlipidemia + + +Discharge Condition: +At mental status baseline, pain controlled, tolerating diet + + +Discharge Instructions: +You were admitted with confusion in the setting of missed +hemodialysis sessions. In the hospital, you had a seizure and a +reaction to a medication which caused your tongue to swell and +necessitated a breathing tube. You had several daily dialysis +sessions and your confusion resolved. You had abdominal pain +which was controlled with Tylenol. Surgery evaluated your wound +and thought you were healing well. You are being discharged to +a rehabilitation facility to regain your strength after the long +hospitalization. + +Followup Instructions: +Please call your primary provider, [**Last Name (NamePattern4) **]. [**Last Name (STitle) **] [**Telephone/Fax (1) 45317**] for +an appointment within 1 week of rehabilitation discharge. + +Surgery Follow Up: Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2122-10-16**] 2:00 + +Neurology Follow Up: Provider: [**Name Initial (NameIs) 1220**]. [**Name5 (PTitle) 540**] & [**Doctor Last Name **] +Phone:[**Telephone/Fax (1) 44**] Date/Time:[**2122-11-10**] 4:30 + +Renal Transplant Appointment: Provider: [**Name10 (NameIs) 2105**] [**Name11 (NameIs) 2106**], MD +Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2123-1-15**] 9:00 + + + +Completed by:[**2122-9-29**]",93,2122-09-22 01:46:00,2122-09-29 18:35:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,ALTERED MENTAL STATUS," +1. altered mental status/seizure/intubation: most likely +etiology is multiple missed hemodialysis sessions/uremia. it is +possible the tylenol with codeine she was taking for post +operative pain control contributed. the morning following +admission she had an episode of decreased responsiveness, clonic +jerks, lip smacking and hand automatisms. she was evaluated by +neurology and was given ativan and depakote for complex partial +seizure. approximately 1 hour after this she became unresponsive +and her tongue was swollen. she was intubated for airway +protection due to angioedema. her mental status normalized +(thought to be related to post-ictal state and medications), eeg +was negative for status epilepticus, head ct and toxicology +screens were negative. the patient required daily dialysis from +[**date range (3) 45315**] and her mental status normalized and was stable +for several days at discharge. + +2. angioedema/respiratory failure: her tongue was noted to be +swollen prior to the administration of depakote during +suctioning prior to intubation. the angioedema seemed to +correlate with the ativan administration. there is a report of +angioedema in the past, attributed to dilantin--but she received +ativan at that time as well. she was treated for 24 hours with +steroids with remarkable improvement. her lisinopril was also +discontinued. her intubation was for airway protection in the +setting of altered mental status and angioedema. she had +persistent apneic episodes on the ventilator and never developed +a cuff leak. she has presumed tracheal stenosis from prior +tracheostomy. she was successfully extubated in the presence of +anesthesia on [**2122-9-25**]. it is recommended she have an outpatient +sleep study to evaluate for obstructive sleep apnea as well as +an outpatient allergy evaluation. + +3. seizures: the patient suffered a partial complex seizure on +the morning after admission. the neurology team followed the +patient throughout her admission. +she was initially loaded with depakote, however, this was then +tapered off and her [**date range 13401**] dosing was increased to 500 mg twice +daily and an additional dose following hemodialysis. she will +follow up with neurology as an outpatient. + +4. esrd on hd: she missed two outpatient hd sessions prior to +admission. she was dialyzed daily in the micu from [**date range (1) 45316**] +then returned to her scheduled of t/t/saturday. + +5. atrial fibrillation: rate control with metoprolol. she had a +single episode of rvr in the ed prior to admission which +responded to labetalol, otherwise, she was effectively rate +controlled. her inr was subtherapeutic at admission, but was +therapeutic at discharge. her inr will need to be followed in +rehabilitation and outpatient monitoring set up prior to +discharge home. + +6. abdominal pain: likely post operative, waxed and waned on +this admission. at the time of discharge, the pain was +controlled by tylenol. her staples were removed by the surgical +team during this hospitalization. she had increased discharge +from her abdominal wound noted on [**2122-9-28**]. the surgery team +evaluated and felt the wound was healing well and there was no +evidence of a wound infection. they recommended daily dry +dressing changes. + +7. benign hypertension: continued on amlodipine and metoprolol. +lisinopril discontinued in the setting of angioedema and not +restarted. the amlodipine was started in its place. her blood +pressure ranged 110-140s/50-70s prior to discharge. + +8. disposition: the patient was discharged to a rehabilitation +facility. she will benefit from a home safety evaluation and +visiting nurses to evaluate medication understanding/compliance. +she requires inr monitoring. as an outpatient, she should have +an allergy evaluation for the recurrent angioedema as well as a +sleep study to evaluate sleep apnea. + + + ","PRIMARY: [Toxic encephalopathy] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Acidosis; Kidney replaced by transplant; Other postoperative infection; Angioneurotic edema, not elsewhere classified; Diabetes with renal manifestations, type II or unspecified type, uncontrolled; Other convulsions; Abdominal pain, left lower quadrant; Other chronic pain; Atrial fibrillation; Apnea; Benzodiazepine-based tranquilizers causing adverse effects in therapeutic use; Diabetes with other specified manifestations, type II or unspecified type, uncontrolled; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Other iatrogenic hypotension; Abnormal coagulation profile; Other and unspecified hyperlipidemia; Osteoarthrosis, unspecified whether generalized or localized, site unspecified; ; Personal history of venous thrombosis and embolism; Long-term (current) use of anticoagulants; Tracheostomy status; Gastrostomy status; Other postprocedural status]" +32247,127308.0,15733,2122-12-31,15730,105172.0,2122-09-10,Discharge summary,"Admission Date: [**2122-9-3**] Discharge Date: [**2122-9-10**] + +Date of Birth: [**2059-1-8**] Sex: F + +Service: MEDICINE + +Allergies: +Percocet / Motrin / Nsaids / Aspirin / Dilantin + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Altered mental status + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +62yo F w/ a PMH of ESRD on HD s/p failed kidney transplant, DVT +(associated w/ HD cath), and HTN who presents to the ED today +after being found on her neighbors stoop confused and apparently +topless. History is primarily taken from EMS reports as the +patient recalls little of the event. Apparently she was feeling +her usual self when she went to HD today. She remembers the ride +home but she states she got off at the wrong street. The next +thing she remembers was being evaluated by EMS. Of note, her FS +was apparently 69 in the field but she is not taking insulin +currently. No history of incontinence, tongue laceration, injury +or LOC. It is not clear how long she was unattended prior to +being found. She had a similar presentation in [**1-13**] with +question of seizure activity but was eventually thought not to +be having seizures. Also reports blood in her urine last night, +and abdominal pain. Reports occasionaly missing her medications, +but always taking her statin and coumadin. Recent change in +coumadin from 5 to 7mg. + +In the ED her vitals were 97.6, 108, 200/100, 100% RA. FS was in +100s on arrival. She received 5mg IV and 100mg PO of metoprolol +which slowed her rate and lowered her BP to more appropriate +levels. She did have episodes of sinus tach up into the 130s +during EJ placement attempts. However, this resolved prior to +transfer. She was evaluated by neurology in the ED who felt that +she was primarily encephalopathic without focality but could not +rule out a seizure. + +Past Medical History: +1. Diabetes mellitus.- unclear hx, not on medication, nl [**Name (NI) **] +2. End-stage renal disease secondary to diabetes mellitus s/p +failed dual kidney transplant +3. Hemodialysis. +4. Hypertension. +5. Hyperlipidemia. +6. Thrombosis of bilateral IVJ (catheter placement)-- DVT +associated with HD catheter RUE on anticoagulation +7. SVC syndrome [**1-13**], s/p thrombectomy, on anticoagulation, +hospitalization complicated by obturator hematoma and required +intubation, PEG and Trach with VAP, and questionable seizure +8. Currently, in hemodialysis. +9. Osteoarthritis. +10. Arthritis of the left knee at age nine, treated with ACTH +resulting in secondary [**Location (un) **]. +11. rheumatic fever as child +12. Afib with RVR + +Past Surgical History: +1. Kidney transplant in [**2119**]. +2. Left arm AV fistula for dialysis. +3. Removal of remnant of AV fistula, left arm. +4. Catheter placement for hemodialysis. +5. Low back surgery (unspecified) + +Social History: +-lives with her nephew [**Name (NI) **], but does not know his number +-Brother is HCP +-[**Name (NI) 1139**]: 10pkyr [**Name2 (NI) 1818**], recently quit but states that she has +restarted and smoking 5 cigs per day +-denies etoh/illicits + +Family History: +Mother and sister with diabetic mellitus. +Kidney failure in mother, sister + + +Physical Exam: +VS: 96.7, 155/84, 83, 20, 98%RA +GEN: Well appearing, NAD +HEENT: NCAT, EOMI, PERRL, oropharynx clear and without erythema +or exudate +NECK: Supple, no LAD, no appreciable JVD +CV: RRR, normal S1S2, systolic murmur at lower sternal border, +no rubs or gallops, 2+ pulses +PULM: CTAB, no w/r/r, good air movement bilaterally +ABD: Soft, ND, mild suprapubic tenderness without rebound or +guarding, normoactive bowel sounds, no organomegaly, no +abdominal bruit appreciated +EXT: Warm and well perfused, full and symmetric distal pulses, +no pedal edema +NEURO: AOx2, trouble with date. Memory [**1-8**] at 2min. Language +fluent. Strength 5/5 in all extremities. Sensation intact to +light touch diffusely. DTRs 2+ bilaterally in patella and +biceps, toes down going. Gait deferred. Seems confused about her +history + +Pertinent Results: +[**2122-9-3**] 01:50PM BLOOD WBC-8.7 RBC-3.84*# Hgb-12.5# Hct-37.0 +MCV-96 MCH-32.5* MCHC-33.8 RDW-15.5 Plt Ct-254# +[**2122-9-10**] 07:59AM BLOOD WBC-9.2 RBC-4.33 Hgb-14.1 Hct-42.7 +MCV-99* MCH-32.5* MCHC-33.0 RDW-15.4 Plt Ct-451* +[**2122-9-3**] 02:46PM BLOOD PT-17.1* PTT-28.0 INR(PT)-1.6* +[**2122-9-10**] 07:59AM BLOOD PT-22.3* INR(PT)-2.1* +[**2122-9-3**] 01:50PM BLOOD Glucose-88 UreaN-15 Creat-4.9* Na-140 +K-3.9 Cl-97 HCO3-28 AnGap-19 +[**2122-9-8**] 07:45AM BLOOD Glucose-88 UreaN-60* Creat-12.2*# Na-139 +K-4.0 Cl-97 HCO3-22 AnGap-24 +[**2122-9-10**] 07:59AM BLOOD Glucose-199* UreaN-47* Creat-9.7*# Na-139 +K-4.0 Cl-92* HCO3-26 AnGap-25* +[**2122-9-3**] 01:50PM BLOOD ALT-13 AST-16 AlkPhos-58 TotBili-0.5 +[**2122-9-3**] 01:50PM BLOOD Calcium-10.1 Phos-3.8 Mg-1.9 +[**2122-9-10**] 07:59AM BLOOD Calcium-9.7 Phos-7.0* Mg-2.3 +[**2122-9-7**] 07:30AM BLOOD VitB12-1032* Folate-GREATER TH +[**2122-9-7**] 07:30AM BLOOD TSH-1.2 +[**2122-9-4**] 05:40AM BLOOD PTH-401* +[**2122-9-3**] 01:50PM BLOOD ASA-NEG Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +[**2122-9-3**] 07:30PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.005 +[**2122-9-3**] 07:30PM URINE Blood-MOD Nitrite-NEG Protein-30 +Glucose-250 Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2122-9-3**] 07:30PM URINE RBC-0-2 WBC-[**6-16**]* Bacteri-FEW Yeast-NONE +Epi-[**11-26**] +[**2122-9-4**] 01:30AM URINE bnzodzp-NEG barbitr-NEG opiates-POS +cocaine-NEG amphetm-NEG mthdone-NEG + +Urine cx ([**9-3**], [**9-4**], [**9-6**]): mixed flora consistent with +contamination +Blood cx ([**9-4**]): 2 negative, 1 NGTD +Cdiff ([**9-6**]): negative + +CXR [**2122-9-3**]: +IMPRESSION: No evidence of acute cardiopulmonary process + +Head CT without Contrast [**2122-9-3**]: +IMPRESSION: No hemorrhage or acute edema. + +EEG [**2122-9-4**]: +IMPRESSION: This is an abnormal routine EEG due to the slow +background, +generalized bursts of slow activity, and multifocal slow +transients with +triphasic features. These findings suggest a widespread +encephalopathy +afecting both cortical and subcortical structures. Medications, +metabolic disturbancies and infections are among the most common +causes. +There were no lateralized or epileptiform features noted. + +Abdominal CT with contrast [**2122-9-4**]: +IMPRESSION: No evidence of abdominal inflammatory process, or +other specific CT finding to explain abdominal pain. + +Head CT without Contrast [**2122-9-6**]: (prelim) +Limited study, despite being repeated, no acute intracranial +hemorrhage +appreciated. + +MRI Head without contrast [**2122-9-7**]: +CONCLUSION: No definite interval change in the appearance of the +brain +compared to the prior study. + +Brief Hospital Course: +1) Altered mental status: Pt with similar presentations in the +past. Labs to evaluate for a toxic-metabolic cause were +unrevealing. She was initially treated with Cipro for a +suspected UTI, but stopped on day 2 as this drug can lower the +seizure threshold and urine grew mixed flora. Head imaging with +CT and MRI was unrevealing. EEG showed generalized slowing. On +the morning of [**9-5**] during her HD treatment, she became very +agitated, confused, and then unresponsive. Her arms were +clutched to her chest in fists and her eyes were deviated to the +left. She was given 1 mg of Ativan and remained disoriented and +somnolent, presumably postictal. Of note, she was also dialyzed +earlier on the day of admission. Neurology was consulted and +felt her presentation was due to fluid and electrolyte shifts +with HD and recommended [**Date Range 13401**] for her apparent seizure. +Dilantin was avoided due to prior drug related angioedema. She +remained confused and agitated, and her somnolence increased. +She was vomiting and minimally responsive to sternal rub. She +was transferred to the MICU for observation, received IV haldol +for agitation, and was called out the next day as she remained +stable. She subsequently received HD two more times with no +adverse reaction. Her mental status improved and she was A&Ox3 +at discharge, although likely with some chronic cognitive +deficits. Her sertraline was held during this admission as well +as on discharge, and can be addressed as an outpatient. + +2) ESRD on HD: She was continued on her Tu/Th/Sat HD schedule. +She was continued on nephrocaps and cinacalcet and started on +sevelamer. + +3) History of DVT/SVC syndrome: Her INR was initially +subtherapeutic at 1.6 and she was bridged on a heparin drip. +With warfarin 5mg daily, it improved to 1.9. However, her +heparin and warfarin were held when her mental status +deteriorated. Once CT head showed no bleed, her heparin was +continued. When decision was made to not perform LP, her +warfarin was restarted and heparin was stopped due to a +therapeutic INR of 2.2. + +Medications on Admission: +ATORVASTATIN - 20 mg by mouth once a day +B COMPLEX-VITAMIN C-FOLIC ACID 1 Capsule(s) by mouth once a day + +CINACALCET 90 mg by mouthonce a day +DARBEPOETIN ALFA IN POLYSORBAT - 40 mcg/mL Solution - once per +week weekly +LISINOPRIL - 5 mg by mouth daily +METOPROLOL TARTRATE - 100 mg by mouth daily +SERTRALINE 100 mg by mouth hs +WARFARIN - - 7 mg by mouth once a day +Tylenol 3 PRN pain + +Discharge Medications: +1. Levetiracetam 250 mg Tablet [**Date Range **]: One (1) Tablet PO QHD (each +hemodialysis). +Disp:*12 Tablet(s)* Refills:*2* +2. Metoprolol Tartrate 50 mg Tablet [**Date Range **]: One (1) Tablet PO twice +a day. +Disp:*60 Tablet(s)* Refills:*2* +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Date Range **]: One (1) Cap +PO DAILY (Daily). +4. Atorvastatin 20 mg Tablet [**Date Range **]: One (1) Tablet PO DAILY +(Daily). +5. Darbepoetin Alfa In Polysorbat 40 mcg/0.4 mL Pen Injector +[**Date Range **]: One (1) Subcutaneous once a week. +6. Lisinopril 5 mg Tablet [**Date Range **]: One (1) Tablet PO DAILY (Daily). + +7. Levetiracetam 250 mg Tablet [**Date Range **]: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +8. Sevelamer HCl 800 mg Tablet [**Date Range **]: One (1) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS): Take with meals. +Disp:*90 Tablet(s)* Refills:*2* +9. Cinacalcet 90 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +10. Warfarin 5 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet [**Date Range **]: One (1) Tablet PO once a day: Take +at same time as 5mg pill. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +Caregroup + +Discharge Diagnosis: +Primary: Altered mental status, seizure history +Secondary: End stage renal disease, status post renal transplant + + +Discharge Condition: +Stable. + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] with confusion. This occurred after +your dialysis. It is possible that you had a seizure during your +confusion. It is not clear what caused the confusion, but it has +improved greatly, with no problems after your last dialysis. + +Please take all medications as prescribed and go to all follow +up appointments. We are holding your sertraline (Zoloft) for now +as this might have contributed to your confusion. We have +started you on [**Last Name (LF) **], [**First Name3 (LF) **] antiseizure medication, with +assistance from the neurologists. We are also starting +sevelamer, a medication to help your electrolytes. Note that you +should take your metoprolol twice daily. + +If you experience any confusion, seizures, weakness, fevers, or +any other concerning symptoms, please seek medical attention or +come to the ER immediately. + +Followup Instructions: +Primary Care: Dr. [**Last Name (STitle) **], ([**Telephone/Fax (1) 45314**], Wed [**9-16**], 1pm +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2122-10-16**] 2:00 +Provider: [**Name Initial (NameIs) 1220**]. [**Name5 (PTitle) 540**] & [**Doctor Last Name **], Neurology Phone:[**Telephone/Fax (1) 44**] +Date/Time:[**2122-11-10**] 4:30 + + + +Completed by:[**2122-9-10**]",112,2122-09-03 20:37:00,2122-09-10 17:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ALTERED MENTAL STATUS," +1) altered mental status: pt with similar presentations in the +past. labs to evaluate for a toxic-metabolic cause were +unrevealing. she was initially treated with cipro for a +suspected uti, but stopped on day 2 as this drug can lower the +seizure threshold and urine grew mixed flora. head imaging with +ct and mri was unrevealing. eeg showed generalized slowing. on +the morning of [**9-5**] during her hd treatment, she became very +agitated, confused, and then unresponsive. her arms were +clutched to her chest in fists and her eyes were deviated to the +left. she was given 1 mg of ativan and remained disoriented and +somnolent, presumably postictal. of note, she was also dialyzed +earlier on the day of admission. neurology was consulted and +felt her presentation was due to fluid and electrolyte shifts +with hd and recommended [**date range 13401**] for her apparent seizure. +dilantin was avoided due to prior drug related angioedema. she +remained confused and agitated, and her somnolence increased. +she was vomiting and minimally responsive to sternal rub. she +was transferred to the micu for observation, received iv haldol +for agitation, and was called out the next day as she remained +stable. she subsequently received hd two more times with no +adverse reaction. her mental status improved and she was a&ox3 +at discharge, although likely with some chronic cognitive +deficits. her sertraline was held during this admission as well +as on discharge, and can be addressed as an outpatient. + +2) esrd on hd: she was continued on her tu/th/sat hd schedule. +she was continued on nephrocaps and cinacalcet and started on +sevelamer. + +3) history of dvt/svc syndrome: her inr was initially +subtherapeutic at 1.6 and she was bridged on a heparin drip. +with warfarin 5mg daily, it improved to 1.9. however, her +heparin and warfarin were held when her mental status +deteriorated. once ct head showed no bleed, her heparin was +continued. when decision was made to not perform lp, her +warfarin was restarted and heparin was stopped due to a +therapeutic inr of 2.2. + + ","PRIMARY: [Altered mental status] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Urinary tract infection, site not specified; Complications of transplanted kidney; Other complications due to renal dialysis device, implant, and graft; Acute venous embolism and thrombosis of unspecified deep vessels of lower extremity; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Surgical operation with transplant of whole organ causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Other and unspecified hyperlipidemia; ; Personal history of noncompliance with medical treatment, presenting hazards to health; Other specified cardiac dysrhythmias; Osteoarthrosis, unspecified whether generalized or localized, site unspecified; ]" +32247,113222.0,15732,2122-09-29,15730,105172.0,2122-09-10,Discharge summary,"Admission Date: [**2122-9-3**] Discharge Date: [**2122-9-10**] + +Date of Birth: [**2059-1-8**] Sex: F + +Service: MEDICINE + +Allergies: +Percocet / Motrin / Nsaids / Aspirin / Dilantin + +Attending:[**First Name3 (LF) 30**] +Chief Complaint: +Altered mental status + +Major Surgical or Invasive Procedure: +None. + + +History of Present Illness: +62yo F w/ a PMH of ESRD on HD s/p failed kidney transplant, DVT +(associated w/ HD cath), and HTN who presents to the ED today +after being found on her neighbors stoop confused and apparently +topless. History is primarily taken from EMS reports as the +patient recalls little of the event. Apparently she was feeling +her usual self when she went to HD today. She remembers the ride +home but she states she got off at the wrong street. The next +thing she remembers was being evaluated by EMS. Of note, her FS +was apparently 69 in the field but she is not taking insulin +currently. No history of incontinence, tongue laceration, injury +or LOC. It is not clear how long she was unattended prior to +being found. She had a similar presentation in [**1-13**] with +question of seizure activity but was eventually thought not to +be having seizures. Also reports blood in her urine last night, +and abdominal pain. Reports occasionaly missing her medications, +but always taking her statin and coumadin. Recent change in +coumadin from 5 to 7mg. + +In the ED her vitals were 97.6, 108, 200/100, 100% RA. FS was in +100s on arrival. She received 5mg IV and 100mg PO of metoprolol +which slowed her rate and lowered her BP to more appropriate +levels. She did have episodes of sinus tach up into the 130s +during EJ placement attempts. However, this resolved prior to +transfer. She was evaluated by neurology in the ED who felt that +she was primarily encephalopathic without focality but could not +rule out a seizure. + +Past Medical History: +1. Diabetes mellitus.- unclear hx, not on medication, nl [**Name (NI) **] +2. End-stage renal disease secondary to diabetes mellitus s/p +failed dual kidney transplant +3. Hemodialysis. +4. Hypertension. +5. Hyperlipidemia. +6. Thrombosis of bilateral IVJ (catheter placement)-- DVT +associated with HD catheter RUE on anticoagulation +7. SVC syndrome [**1-13**], s/p thrombectomy, on anticoagulation, +hospitalization complicated by obturator hematoma and required +intubation, PEG and Trach with VAP, and questionable seizure +8. Currently, in hemodialysis. +9. Osteoarthritis. +10. Arthritis of the left knee at age nine, treated with ACTH +resulting in secondary [**Location (un) **]. +11. rheumatic fever as child +12. Afib with RVR + +Past Surgical History: +1. Kidney transplant in [**2119**]. +2. Left arm AV fistula for dialysis. +3. Removal of remnant of AV fistula, left arm. +4. Catheter placement for hemodialysis. +5. Low back surgery (unspecified) + +Social History: +-lives with her nephew [**Name (NI) **], but does not know his number +-Brother is HCP +-[**Name (NI) 1139**]: 10pkyr [**Name2 (NI) 1818**], recently quit but states that she has +restarted and smoking 5 cigs per day +-denies etoh/illicits + +Family History: +Mother and sister with diabetic mellitus. +Kidney failure in mother, sister + + +Physical Exam: +VS: 96.7, 155/84, 83, 20, 98%RA +GEN: Well appearing, NAD +HEENT: NCAT, EOMI, PERRL, oropharynx clear and without erythema +or exudate +NECK: Supple, no LAD, no appreciable JVD +CV: RRR, normal S1S2, systolic murmur at lower sternal border, +no rubs or gallops, 2+ pulses +PULM: CTAB, no w/r/r, good air movement bilaterally +ABD: Soft, ND, mild suprapubic tenderness without rebound or +guarding, normoactive bowel sounds, no organomegaly, no +abdominal bruit appreciated +EXT: Warm and well perfused, full and symmetric distal pulses, +no pedal edema +NEURO: AOx2, trouble with date. Memory [**1-8**] at 2min. Language +fluent. Strength 5/5 in all extremities. Sensation intact to +light touch diffusely. DTRs 2+ bilaterally in patella and +biceps, toes down going. Gait deferred. Seems confused about her +history + +Pertinent Results: +[**2122-9-3**] 01:50PM BLOOD WBC-8.7 RBC-3.84*# Hgb-12.5# Hct-37.0 +MCV-96 MCH-32.5* MCHC-33.8 RDW-15.5 Plt Ct-254# +[**2122-9-10**] 07:59AM BLOOD WBC-9.2 RBC-4.33 Hgb-14.1 Hct-42.7 +MCV-99* MCH-32.5* MCHC-33.0 RDW-15.4 Plt Ct-451* +[**2122-9-3**] 02:46PM BLOOD PT-17.1* PTT-28.0 INR(PT)-1.6* +[**2122-9-10**] 07:59AM BLOOD PT-22.3* INR(PT)-2.1* +[**2122-9-3**] 01:50PM BLOOD Glucose-88 UreaN-15 Creat-4.9* Na-140 +K-3.9 Cl-97 HCO3-28 AnGap-19 +[**2122-9-8**] 07:45AM BLOOD Glucose-88 UreaN-60* Creat-12.2*# Na-139 +K-4.0 Cl-97 HCO3-22 AnGap-24 +[**2122-9-10**] 07:59AM BLOOD Glucose-199* UreaN-47* Creat-9.7*# Na-139 +K-4.0 Cl-92* HCO3-26 AnGap-25* +[**2122-9-3**] 01:50PM BLOOD ALT-13 AST-16 AlkPhos-58 TotBili-0.5 +[**2122-9-3**] 01:50PM BLOOD Calcium-10.1 Phos-3.8 Mg-1.9 +[**2122-9-10**] 07:59AM BLOOD Calcium-9.7 Phos-7.0* Mg-2.3 +[**2122-9-7**] 07:30AM BLOOD VitB12-1032* Folate-GREATER TH +[**2122-9-7**] 07:30AM BLOOD TSH-1.2 +[**2122-9-4**] 05:40AM BLOOD PTH-401* +[**2122-9-3**] 01:50PM BLOOD ASA-NEG Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +[**2122-9-3**] 07:30PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.005 +[**2122-9-3**] 07:30PM URINE Blood-MOD Nitrite-NEG Protein-30 +Glucose-250 Ketone-NEG Bilirub-NEG Urobiln-NEG pH-8.0 Leuks-NEG +[**2122-9-3**] 07:30PM URINE RBC-0-2 WBC-[**6-16**]* Bacteri-FEW Yeast-NONE +Epi-[**11-26**] +[**2122-9-4**] 01:30AM URINE bnzodzp-NEG barbitr-NEG opiates-POS +cocaine-NEG amphetm-NEG mthdone-NEG + +Urine cx ([**9-3**], [**9-4**], [**9-6**]): mixed flora consistent with +contamination +Blood cx ([**9-4**]): 2 negative, 1 NGTD +Cdiff ([**9-6**]): negative + +CXR [**2122-9-3**]: +IMPRESSION: No evidence of acute cardiopulmonary process + +Head CT without Contrast [**2122-9-3**]: +IMPRESSION: No hemorrhage or acute edema. + +EEG [**2122-9-4**]: +IMPRESSION: This is an abnormal routine EEG due to the slow +background, +generalized bursts of slow activity, and multifocal slow +transients with +triphasic features. These findings suggest a widespread +encephalopathy +afecting both cortical and subcortical structures. Medications, +metabolic disturbancies and infections are among the most common +causes. +There were no lateralized or epileptiform features noted. + +Abdominal CT with contrast [**2122-9-4**]: +IMPRESSION: No evidence of abdominal inflammatory process, or +other specific CT finding to explain abdominal pain. + +Head CT without Contrast [**2122-9-6**]: (prelim) +Limited study, despite being repeated, no acute intracranial +hemorrhage +appreciated. + +MRI Head without contrast [**2122-9-7**]: +CONCLUSION: No definite interval change in the appearance of the +brain +compared to the prior study. + +Brief Hospital Course: +1) Altered mental status: Pt with similar presentations in the +past. Labs to evaluate for a toxic-metabolic cause were +unrevealing. She was initially treated with Cipro for a +suspected UTI, but stopped on day 2 as this drug can lower the +seizure threshold and urine grew mixed flora. Head imaging with +CT and MRI was unrevealing. EEG showed generalized slowing. On +the morning of [**9-5**] during her HD treatment, she became very +agitated, confused, and then unresponsive. Her arms were +clutched to her chest in fists and her eyes were deviated to the +left. She was given 1 mg of Ativan and remained disoriented and +somnolent, presumably postictal. Of note, she was also dialyzed +earlier on the day of admission. Neurology was consulted and +felt her presentation was due to fluid and electrolyte shifts +with HD and recommended [**Date Range 13401**] for her apparent seizure. +Dilantin was avoided due to prior drug related angioedema. She +remained confused and agitated, and her somnolence increased. +She was vomiting and minimally responsive to sternal rub. She +was transferred to the MICU for observation, received IV haldol +for agitation, and was called out the next day as she remained +stable. She subsequently received HD two more times with no +adverse reaction. Her mental status improved and she was A&Ox3 +at discharge, although likely with some chronic cognitive +deficits. Her sertraline was held during this admission as well +as on discharge, and can be addressed as an outpatient. + +2) ESRD on HD: She was continued on her Tu/Th/Sat HD schedule. +She was continued on nephrocaps and cinacalcet and started on +sevelamer. + +3) History of DVT/SVC syndrome: Her INR was initially +subtherapeutic at 1.6 and she was bridged on a heparin drip. +With warfarin 5mg daily, it improved to 1.9. However, her +heparin and warfarin were held when her mental status +deteriorated. Once CT head showed no bleed, her heparin was +continued. When decision was made to not perform LP, her +warfarin was restarted and heparin was stopped due to a +therapeutic INR of 2.2. + +Medications on Admission: +ATORVASTATIN - 20 mg by mouth once a day +B COMPLEX-VITAMIN C-FOLIC ACID 1 Capsule(s) by mouth once a day + +CINACALCET 90 mg by mouthonce a day +DARBEPOETIN ALFA IN POLYSORBAT - 40 mcg/mL Solution - once per +week weekly +LISINOPRIL - 5 mg by mouth daily +METOPROLOL TARTRATE - 100 mg by mouth daily +SERTRALINE 100 mg by mouth hs +WARFARIN - - 7 mg by mouth once a day +Tylenol 3 PRN pain + +Discharge Medications: +1. Levetiracetam 250 mg Tablet [**Date Range **]: One (1) Tablet PO QHD (each +hemodialysis). +Disp:*12 Tablet(s)* Refills:*2* +2. Metoprolol Tartrate 50 mg Tablet [**Date Range **]: One (1) Tablet PO twice +a day. +Disp:*60 Tablet(s)* Refills:*2* +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Date Range **]: One (1) Cap +PO DAILY (Daily). +4. Atorvastatin 20 mg Tablet [**Date Range **]: One (1) Tablet PO DAILY +(Daily). +5. Darbepoetin Alfa In Polysorbat 40 mcg/0.4 mL Pen Injector +[**Date Range **]: One (1) Subcutaneous once a week. +6. Lisinopril 5 mg Tablet [**Date Range **]: One (1) Tablet PO DAILY (Daily). + +7. Levetiracetam 250 mg Tablet [**Date Range **]: One (1) Tablet PO BID (2 +times a day). +Disp:*60 Tablet(s)* Refills:*2* +8. Sevelamer HCl 800 mg Tablet [**Date Range **]: One (1) Tablet PO TID +W/MEALS (3 TIMES A DAY WITH MEALS): Take with meals. +Disp:*90 Tablet(s)* Refills:*2* +9. Cinacalcet 90 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +10. Warfarin 5 mg Tablet [**Date Range **]: One (1) Tablet PO once a day. +Disp:*30 Tablet(s)* Refills:*2* +11. Warfarin 2 mg Tablet [**Date Range **]: One (1) Tablet PO once a day: Take +at same time as 5mg pill. +Disp:*30 Tablet(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +Caregroup + +Discharge Diagnosis: +Primary: Altered mental status, seizure history +Secondary: End stage renal disease, status post renal transplant + + +Discharge Condition: +Stable. + + +Discharge Instructions: +You were admitted to [**Hospital1 18**] with confusion. This occurred after +your dialysis. It is possible that you had a seizure during your +confusion. It is not clear what caused the confusion, but it has +improved greatly, with no problems after your last dialysis. + +Please take all medications as prescribed and go to all follow +up appointments. We are holding your sertraline (Zoloft) for now +as this might have contributed to your confusion. We have +started you on [**Last Name (LF) **], [**First Name3 (LF) **] antiseizure medication, with +assistance from the neurologists. We are also starting +sevelamer, a medication to help your electrolytes. Note that you +should take your metoprolol twice daily. + +If you experience any confusion, seizures, weakness, fevers, or +any other concerning symptoms, please seek medical attention or +come to the ER immediately. + +Followup Instructions: +Primary Care: Dr. [**Last Name (STitle) **], ([**Telephone/Fax (1) 45314**], Wed [**9-16**], 1pm +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] +Date/Time:[**2122-10-16**] 2:00 +Provider: [**Name Initial (NameIs) 1220**]. [**Name5 (PTitle) 540**] & [**Doctor Last Name **], Neurology Phone:[**Telephone/Fax (1) 44**] +Date/Time:[**2122-11-10**] 4:30 + + + +Completed by:[**2122-9-10**]",19,2122-09-03 20:37:00,2122-09-10 17:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ALTERED MENTAL STATUS," +1) altered mental status: pt with similar presentations in the +past. labs to evaluate for a toxic-metabolic cause were +unrevealing. she was initially treated with cipro for a +suspected uti, but stopped on day 2 as this drug can lower the +seizure threshold and urine grew mixed flora. head imaging with +ct and mri was unrevealing. eeg showed generalized slowing. on +the morning of [**9-5**] during her hd treatment, she became very +agitated, confused, and then unresponsive. her arms were +clutched to her chest in fists and her eyes were deviated to the +left. she was given 1 mg of ativan and remained disoriented and +somnolent, presumably postictal. of note, she was also dialyzed +earlier on the day of admission. neurology was consulted and +felt her presentation was due to fluid and electrolyte shifts +with hd and recommended [**date range 13401**] for her apparent seizure. +dilantin was avoided due to prior drug related angioedema. she +remained confused and agitated, and her somnolence increased. +she was vomiting and minimally responsive to sternal rub. she +was transferred to the micu for observation, received iv haldol +for agitation, and was called out the next day as she remained +stable. she subsequently received hd two more times with no +adverse reaction. her mental status improved and she was a&ox3 +at discharge, although likely with some chronic cognitive +deficits. her sertraline was held during this admission as well +as on discharge, and can be addressed as an outpatient. + +2) esrd on hd: she was continued on her tu/th/sat hd schedule. +she was continued on nephrocaps and cinacalcet and started on +sevelamer. + +3) history of dvt/svc syndrome: her inr was initially +subtherapeutic at 1.6 and she was bridged on a heparin drip. +with warfarin 5mg daily, it improved to 1.9. however, her +heparin and warfarin were held when her mental status +deteriorated. once ct head showed no bleed, her heparin was +continued. when decision was made to not perform lp, her +warfarin was restarted and heparin was stopped due to a +therapeutic inr of 2.2. + + ","PRIMARY: [Altered mental status] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; Urinary tract infection, site not specified; Complications of transplanted kidney; Other complications due to renal dialysis device, implant, and graft; Acute venous embolism and thrombosis of unspecified deep vessels of lower extremity; Epilepsy, unspecified, without mention of intractable epilepsy; Long-term (current) use of anticoagulants; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Surgical operation with transplant of whole organ causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Other and unspecified hyperlipidemia; ; Personal history of noncompliance with medical treatment, presenting hazards to health; Other specified cardiac dysrhythmias; Osteoarthrosis, unspecified whether generalized or localized, site unspecified; ]" +32247,127308.0,15733,2122-12-31,15731,180961.0,2122-09-17,Discharge summary,"Admission Date: [**2122-9-11**] Discharge Date: [**2122-9-17**] + +Date of Birth: [**2059-1-8**] Sex: F + +Service: SURGERY + +Allergies: +Percocet / Motrin / Nsaids / Aspirin / Dilantin + +Attending:[**First Name3 (LF) 668**] +Chief Complaint: +Abdominal pain + +Major Surgical or Invasive Procedure: +[**2122-9-13**]: negative exploratory laparotomy + + +History of Present Illness: +62yo F w/ a PMH of ESRD on HD s/p failed kidney transplant, +DVT (associated w/ HD cath), and HTN who presents to the ED +today +with right lower quadrant abdominal pain and hypotension. She +was +nauseated last night and had vomiting x 1. Nonbloody, +nonbilious. +Last bowel movement was 2 days ago. Not constipated. No +diarrhea. No fever chillls or night sweats. She has had the +abdominal pain for weeks. Food makes the pain better. She has +not eaten today so the pain has gotten worse over the last +couple +of days. + + +Past Medical History: +1. Diabetes mellitus.- unclear hx, not on medication, nl [**Name (NI) **] +2. End-stage renal disease secondary to diabetes mellitus s/p +failed dual kidney transplant +3. Hemodialysis. +4. Hypertension. +5. Hyperlipidemia. +6. Thrombosis of bilateral IVJ (catheter placement)-- DVT +associated with HD catheter RUE on anticoagulation +7. SVC syndrome [**1-13**], s/p thrombectomy, on anticoagulation, +hospitalization complicated by obturator hematoma and required +intubation, PEG and Trach with VAP, and questionable seizure +8. Currently, in hemodialysis. +9. Osteoarthritis. +10. Arthritis of the left knee at age nine, treated with ACTH +resulting in secondary [**Location (un) **]. +11. rheumatic fever as child +12. Afib with RVR + +Past Surgical History: +1. Kidney transplant in [**2119**]. +2. Left arm AV fistula for dialysis. +3. Removal of remnant of AV fistula, left arm. +4. Catheter placement for hemodialysis. +5. Low back surgery (unspecified) + +Social History: +-lives with her nephew [**Name (NI) **], but does not know his number +-Brother is HCP +-[**Name (NI) 1139**]: 10pkyr [**Name2 (NI) 1818**], recently quit but states that she has +restarted and smoking 5 cigs per day +-denies etoh/illicits + + +Family History: +Mother and sister with diabetes mellitus. +Kidney failure in mother, sister + + +Physical Exam: +Vital signs: T 96.0 HR 110 BP 96/46 RR 16 O2sat 95% on RA +General: No acute distress +Cardiovascular: regular rate and rhythm, systolic murmur +Pulmonary: clear to ausculation bilaterally +Abdomen: Soft, nondisteded, tender to palpation in the +suprapubic +area and in the right lower quadrant, no guarding +Rectal exam: guiac negative, no gross blood, no hemorrhoids on +exam + + +Pertinent Results: +On Admission: [**2122-9-10**] +WBC-9.2 RBC-4.33 Hgb-14.1 Hct-42.7 MCV-99* MCH-32.5* MCHC-33.0 +RDW-15.4 Plt Ct-451* +PT-22.3* INR(PT)-2.1* +Glucose-199* UreaN-47* Creat-9.7*# Na-139 K-4.0 Cl-92* HCO3-26 +AnGap-25* +ALT-9 AST-12 AlkPhos-45 TotBili-0.3 +Calcium-9.7 Phos-7.0* Mg-2.3 +On Discharge [**2122-9-17**] +WBC-6.2 RBC-2.94* Hgb-9.5* Hct-29.9* MCV-102* MCH-32.4* +MCHC-31.9 RDW-14.5 Plt Ct-317 +PT-31.2* PTT-40.3* INR(PT)-3.2* +K-3.6 + +Brief Hospital Course: +63 y/o female s/p failed kidney transplant in past and recent +admission for She now returns with abdominal pain. +A CT scan of the abdomen demonstrated portal venous air and +pneumatosis involving the right colon. She was taken to the OR +with Dr [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **]. In summary, upon inspection of the +peritoneal cavity there was no free fluid. No fibrinous exudate +and no foul smell. There was virtually no adhesions in the +abdominal cavity. The +terminal ileum was identified. This was run retrograde to the +ligament Treitz without evidence of small bowel pathology. There +was no significant pathology involving the right colon. No +evidence of the pneumatosis or gangrenous changes were +identified. The colon was run from the right colon to the distal +sigmoid. Multiple diverticula are noted throughout the +left-sided colon as well +as 1 or 2 small diverticula in the small bowel, but again no +evidence of perforation, no gangrenous changes, no pneumatosis +was identified. There was no fibrinous exudate. +In the PACU following the case she became increasingly +somnolent, BP hypertensive, she was reintubated and transferred +to the ICU. She was started on IV Levaquin. +She was extubated on POD 1 and remained stable thereafter. +HD via tunneled line with last HD on [**9-16**] with 2 Liters removed. +She was kept on telemetry and had an episode of tachycardia +which resolved without additional beta blockade. +Every day she became more alert and more able to participate +with PT, so she was able to be discharged home with full +services for OT/PT, nursing and social work +Coumadin restarting [**9-19**] with PT/INR to be drawn and results +faxed to [**First Name8 (NamePattern2) 5969**] [**Last Name (NamePattern1) 5970**] by the VNA. She will then resume +monitoring with Dr[**Name (NI) 4849**] at [**Location (un) **] as she was +pre-hospitalization. Next HD Saturday [**9-20**]. Stable per renal. + + +Medications on Admission: +ATORVASTATIN [LIPITOR] - (Prescribed by Other Provider) - 20 mg +Tablet - 1 Tablet(s) by mouth once a day +B COMPLEX-VITAMIN C-FOLIC ACID [RENAL CAPS] - (Prescribed by +Other Provider) - 1 mg Capsule - 1 Capsule(s) by mouth once a +day +CINACALCET [SENSIPAR] - (Prescribed by Other Provider; Dose +adjustment - no new Rx) - 90 mg Tablet - 1 Tablet(s) by mouth +once a day +DARBEPOETIN ALFA IN POLYSORBAT [ARANESP (POLYSORBATE)] - +(Prescribed by Other Provider) - 40 mcg/mL Solution - once per +week weekly +LISINOPRIL - (Prescribed by Other Provider) - 5 mg Tablet - 1 +Tablet(s) by mouth daily +METOPROLOL TARTRATE - (Prescribed by Other Provider) - 100 mg +Tablet - 1 Tablet by mouth daily +SERTRALINE [ZOLOFT] - (Prescribed by Other Provider) - 100 mg +Tablet - 1 Tablet(s) by mouth hs +WARFARIN - (Prescribed by Other Provider) - 2 mg Tablet - 4 +Tablet(s) by mouth once a day + + +Discharge Medications: +1. Metoprolol Succinate 100 mg Tablet Sustained Release 24 hr +[**Month/Year (2) **]: One (1) Tablet Sustained Release 24 hr PO once a day. +2. Atorvastatin 20 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. + +3. B Complex-Vitamin C-Folic Acid 1 mg Capsule [**Month/Year (2) **]: One (1) Cap +PO DAILY (Daily). +4. Cinacalcet 90 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. +5. Sertraline 100 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO once a day. +6. Lisinopril 5 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO DAILY (Daily). + +7. Acetaminophen-Codeine 300-30 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO +Q4H (every 4 hours) as needed for pain. +Disp:*20 Tablet(s)* Refills:*0* +8. Warfarin 1 mg Tablet [**Month/Year (2) **]: Two (2) Tablet PO once a day: +Please restart [**2122-9-18**]. Do NOT dose on [**9-17**]. +9. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO twice a +day: Started with previous admission, scripts given at last +discharge. +Disp:*90 Tablet(s)* Refills:*2* +10. Levetiracetam 250 mg Tablet [**Month/Year (2) **]: One (1) Tablet PO following +HD. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Abdominal pain s/p ex-lap for potential small bowel obstruction, +which was negative + + +Discharge Condition: +Good + + +Discharge Instructions: +Please call the transplant clinic at [**Telephone/Fax (1) 673**] for fever > +101, chills, nausea, vomiting, diarrhea, increased abdominal +pain, inability to take or keep down medications. +Monitor incision for redness, drainage or bleeding. Incison may +be left open to air. +Continue hemodialysis via left tunneled dialysis line. Next HD +[**9-19**] at [**Location (un) **] +Continue food, fluid and medications per renal recommendations +No showering with dialysis catheter +Dr[**Name (NI) **] at [**Location (un) **] dialysis will continue to follow +PT/INR, dialysis unit aware + +Followup Instructions: +[**Last Name (LF) **],[**First Name3 (LF) **] TRANSPLANT SOCIAL WORK Date/Time:[**2122-9-25**] 1:00 +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time: [**2122-9-25**] 2 PM +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1330**], MD Phone:[**Telephone/Fax (1) 673**] Date/Time:[**2122-10-16**] 2:00 +[**Month/Day/Year 1220**]. [**Name5 (PTitle) 540**] & [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 44**] Date/Time:[**2122-11-10**] +4:30 + + + +Completed by:[**2122-9-17**]",105,2122-09-11 22:13:00,2122-09-17 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,BENIGN PNEUMATOSIS," +63 y/o female s/p failed kidney transplant in past and recent +admission for she now returns with abdominal pain. +a ct scan of the abdomen demonstrated portal venous air and +pneumatosis involving the right colon. she was taken to the or +with dr [**first name8 (namepattern2) **] [**last name (namepattern1) **]. in summary, upon inspection of the +peritoneal cavity there was no free fluid. no fibrinous exudate +and no foul smell. there was virtually no adhesions in the +abdominal cavity. the +terminal ileum was identified. this was run retrograde to the +ligament treitz without evidence of small bowel pathology. there +was no significant pathology involving the right colon. no +evidence of the pneumatosis or gangrenous changes were +identified. the colon was run from the right colon to the distal +sigmoid. multiple diverticula are noted throughout the +left-sided colon as well +as 1 or 2 small diverticula in the small bowel, but again no +evidence of perforation, no gangrenous changes, no pneumatosis +was identified. there was no fibrinous exudate. +in the pacu following the case she became increasingly +somnolent, bp hypertensive, she was reintubated and transferred +to the icu. she was started on iv levaquin. +she was extubated on pod 1 and remained stable thereafter. +hd via tunneled line with last hd on [**9-16**] with 2 liters removed. +she was kept on telemetry and had an episode of tachycardia +which resolved without additional beta blockade. +every day she became more alert and more able to participate +with pt, so she was able to be discharged home with full +services for ot/pt, nursing and social work +coumadin restarting [**9-19**] with pt/inr to be drawn and results +faxed to [**first name8 (namepattern2) 5969**] [**last name (namepattern1) 5970**] by the vna. she will then resume +monitoring with dr[**name (ni) 4849**] at [**location (un) **] as she was +pre-hospitalization. next hd saturday [**9-20**]. stable per renal. + + + ","PRIMARY: [Other specified disorders of intestine] +SECONDARY: [End stage renal disease; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage V or end stage renal disease; ; Acidosis; Diabetes with renal manifestations, type II or unspecified type, not stated as uncontrolled; Atrial fibrillation; Hypotension, unspecified; ]" +40526,101343.0,18227,2123-06-06,18226,100456.0,2123-05-25,Discharge summary,"Admission Date: [**2123-4-26**] Discharge Date: [**2123-5-25**] + +Date of Birth: [**2091-8-18**] Sex: F + +Service: SURGERY + +Allergies: +Codeine / Remicade / Vancomycin + +Attending:[**First Name3 (LF) 3376**] +Chief Complaint: +Admit Crohn's flare with abscess to Surgery + +Major Surgical or Invasive Procedure: +[**4-29**] CT-guided placement of drainage catheter into pelvic +abscess. Scant thick pus aspirated initially. +[**5-4**] The indwelling right pelvic catheter was easily exchanged +for a similar cathete +[**5-12**] CT-guided placement of two pigtail drainage catheters in +two residual intra-abdominal abscess collections. +[**5-14**] washout/ex-lap/drain placement + + +History of Present Illness: +31F with h/o Crohn's disease refractory to medical mgmt +(remicade, etc) currently on slow steroid taper. Recently +admitted [**2-25**] with microperforation. Dr. [**Last Name (STitle) 1120**] planned on +ileocecectomy on [**5-5**]. The pt now presents with epigastric pain +X 2 weeks in spite of being on cipro, flagyl, prednisone. Flagyl +d/c'd 2 weeks ago and put on prilosec by Dr. [**Last Name (STitle) 2161**]. Over past +week, pain is worse and in past 24 hrs severe [**6-28**] pain in +epigastrum and RLQ. Pt reports sweating but denies fevers. This +AM, following taking her PO mediacation the pt reported emesis +10-15 times. She also noted [**8-28**] abdominal pain, mostly RLQ, +but also LUQ. Loose stools no melena or BRBPR. Pt reports dry +mouth but denies lighheadedness, dizziness, visual changes or +other presyncopal symptoms. + +In ED, 99,4 115/69 120 17 100%RA. While in the ED, Tm 101.4 and +tachy to 130s, normotensive. WBC 5.1 with 15% bandemia, diffuse +peritonitis and rigid abdomen, diffusely tender. CT abd/pelvis +with likely early developing abscess with pockets of free air in +pelvis. The pt received 4L of NS, Dilaudid 1mg IV x7, Morphine +4mg IV, Zofran 4gm IX x1 for pain and tylenol 1gm PO. Abx were +initially continued with Cipro 400mg IV and Flagyl 500mg IV +which was later switched to Vanc 1g IV and Zosyn 4.5mg was +given. An NG tube was placed which the pt states relieved some +of her abdominal bloating. + +Upon further review of systems: +(+) Per HPI +(-) Denies chills, night sweats, recent weight loss or gain. +Denies headache, sinus tenderness, rhinorrhea or congestion. +Denied cough, shortness of breath. Occasional chest pressure, +but denies tightness, palpitations. Denied nausea, vomiting, +diarrhea, constipation or abdominal pain. The pt stated it took +her 3-4 minutes to initiate urination today in the setting of +increased abdominal pain. Denies dysuria. + +Past Medical History: +Crohn's Disease +Depression +h/o arthritis related to medications +Anorexia Nervosa/OCD + +Past Surgical History +s/p Wisdom teeth removal in [**2103**] +LEEP procedure in [**2121**] + +Primary Care Physician: [**Last Name (NamePattern4) **]. [**Last Name (STitle) 5781**] +GI: Dr. [**Last Name (STitle) 2161**] + +Social History: +Works at [**Hospital3 328**] in PR department +[**11-21**] EtOH drinks, ~3 times per week +smoked [**11-20**] ppd X 3-4yrs quit 9 years ago + +Family History: +Cousin with [**Name (NI) 4522**] Disease +Father CAD + +Physical Exam: +Vitals: T: 99.9 BP: 117/72 P: 114 R: 24-29 93-96%O2: +General: Alert, oriented, NAD when lying still +HEENT: Dry MMM, PERRLA, EOMI +Neck: supple, JVP 6-7cm, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: Tachycardic, normal S1 + S2, no murmurs, rubs, gallops +Abdomen: firm, diffusely tender, non-distended, hypoactive bowel +sounds present. + Guarding. Tenderness to palpation > Rebound. +Ext: Warm. 2+ pulses, no clubbing, cyanosis or edema +. +at discharge: +Gen: a and o x 3, nad +CV: RRR no m/r/g +RESP: LSCTA bilat +ABD: Soft, nt, nd, + bs +Incision: ota with steri strips + + +Pertinent Results: +CT Abdomen (Wet-Read) [**2123-4-26**] +1. Increased size of pelvic collection, Image 2:61, with +multiple tiny pockets of extraluminal air. The collection shows +early signs of organizing to an abscess. +2. Worsening of bowel wall thickening, consistent with Crohn's +flare. +CT Abdomen [**2123-4-28**] (wet read) +Marked interval increase in intraperitoneal fluid tracking +through the +mesentery, around the liver, and collecting in the pelvis. Large +pre-sacral pelvic collection has increased in size and +demonstrates increased rim enhancement, concerning for +developing abscess. Hyperemic mesentery and omental inflammatory +changes, likely worsened since the prior study. Focal collection +previously identified in the mid-pelvis appears largely +unchanged. Redemonstration of bowel wall abnormalities c/w +Crohn's flare, largely stable. +. +IMAGING +[**3-18**] CT abd: wall thickening/inflammatory fat stranding of TI, +cecum, hepatic flexure, 2.4 cm early abscess adj to cecum +[**4-26**] CT abd: inc pelvic fluid collection w/ mult tiny pockets of +extraluminal air, early signs of organization, worsening bowel +wall thickening +[**4-28**] CT abd: marked inc intraperitoneal fluid tracking thru +mesentery, around liver, [**Last Name (un) **] in pelvis, lg pre-sacral +pelvic [**Last Name (un) **] inc in size w/ inc rim enhancement, ? abscess, +worsened hyperemic mesentery & omental inflamm changes, focal +[**Last Name (un) **] in mid-pelvis largely unchanged, stable bowel wall abnl +[**5-9**] CT abd: interval [**Month (only) **] pelvic fluid [**Last Name (un) **], o/w stable +[**5-10**] RUE U/S: no dvt +[**5-12**] CT: drains in place +[**5-13**] CXR: increased L eff, atelectasis, new R eff improved on +CXR [**5-16**] +. + [**2123-5-16**] Blood Cx2 +[**2123-5-16**] urine +[**2123-5-16**] cxr [**Month (only) **]. lf pleural effusion,consol or pneumo lt base +is not excluded +[**2123-5-14**] Tissue(OR) PMN, no growth +[**2123-5-13**] CXR Increased left effusion/atelectasis and new small +right effusion +[**2123-5-12**] abcess x2 GRAM POSITIVE COCCI (pairs) (pairs/clusters). +PMNs +[**2123-5-12**] bld times 4 negative +[**2123-5-11**] urine neg +[**2123-5-10**] bld x2 negative +[**2123-5-10**] urine neg +[**2123-5-8**] bld negative +[**2123-5-5**] abscess C.albicans, s. viridans AND lactobacillus +[**2123-5-4**] abscess C.albicans, S.viridans, lactobacillus +[**2123-4-29**] abscess >3 bacterial types + + +Brief Hospital Course: +31F here with long-standing refractory Crohn's presenting with a +severe flare and intravascular depletion. +. +# Abdominal Pain/Surgical Abdomen: Most likely [**12-21**] Crohn's Flare +given findings on CT (Multiple Tiny Pockets of Extraluminal Air, +Worsening bowel wall thickening consistent with Crohns flare). +Other less likely etiologies include perforated ulcer (given +chronic steroid use). Evaluated by surgery in ED and upon +admission to [**Hospital Unit Name 153**]. Received IV vancomycin/zosyn. Per GI to +continue hydrcortisone 100 mg qdaily. NGT placed. Foley in +place. Strict NPO, serial abd exam. +- NPO +- Serial Abdominal Exam +-Antibiotics +-Hydrocortisone 100mg Daily +- Morphine 2-4mg IV PRN Abdominal Pain +. +# Sinus Tachycardia: In the setting of intravascular depletion, +crohns flare, abdominal pain. +- IVF resuscitation +- Pain Control with Morphine 2-4mg IV PRN +- Broad Spectrum ABx + +. +The patient was transferred to [**Hospital Ward Name 1950**] 5 she was made NPO with +IVF/Foley/IVMeds/ABX. She was febrile to 102.9 with increased +pain. Her pain medication was changed from morphine to dilaudid +with good effect. The patient also had a repeat CT scan showing +a fluid collection in her abdomen. She was taken to IR to have a +drain place. Scant thick pus aspirated and cultured. +. +A PICC line was placed and the patient was started on TPN with +bowel rest. She continued to spike temps to 103.0. Multiple +fever workups were done including BCX, UCX and CXR all negative +for infection. She had multiple CT scans done indicating +abcesses. She was taken to IR for Drain placement, 2 drains +placed for a total of 4 drains. +. +Despite the drain placements the patient continued to spike +temps to 104.6 on HD 19 requiring a cooling blanket. She was +than pre-op'd and taken to the OR for ex-lap, washout and drain +placement. +. +She returned to the floor. She was maintained as NPO, TPN was +continued along with a PCA, IVF, ABX. Infectious disease was +also consulted to recommend treatment. POD 1 the patient was +afebrile. However she continued to spike daily fevers there on +out. ID continued to follow the patient adjust antibiotics as +needed. +. +The patient c/o of severe pain and the pain service was +consulted. She was started on a fentynal patch and PO dilaudid +with good effect. At discharge the patient no longer needed the +fentynal patch, her pain was well controlled with dilaudid. Her +TPN was cycled and with the return of bowel function and flatus +her diet was advanced from sips to regular. Her TPN was d/c'd +once she tolerated regular diet. +All of her drains were d/c'd prior to d/c. The patient was +encouraged to have ensure with all meals. All D/C paperwork was +reviewed with the patient and all questions answered. She will +follow up with Dr. [**Last Name (STitle) 1120**] in [**11-20**] weeks. + +Medications on Admission: +Ciprofloxacin 500 mg [**Hospital1 **] +Celexa 20mg qday +Protonix 40 mg qday +Prednisone 25 mg qday +Ambien 10 mg qday PRN +OCP +Folate +MVI +CITRACAL + Vit D 250 mg-200 unit PO TID + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H (every +6 hours) as needed for fever. +Disp:*60 Tablet(s)* Refills:*2* +2. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Hydromorphone 4 mg Tablet Sig: 1-2 Tablets PO Q3H (every 3 +hours) as needed for pain for 2 weeks. +Disp:*50 Tablet(s)* Refills:*0* +4. Iron (Ferrous Sulfate) 325 mg (65 mg Iron) Tablet Sig: One +(1) Tablet PO once a day. +5. Ciprofloxacin 500 mg Tablet Sig: One (1) Tablet PO Q12H +(every 12 hours). +Disp:*60 Tablet(s)* Refills:*2* +6. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +7. Budesonide 3 mg Capsule, Sust. Release 24 hr Sig: Three (3) +Capsule, Sust. Release 24 hr PO DAILY (Daily) for 8 weeks. +Disp:*168 Capsule, Sust. Release 24 hr(s)* Refills:*0* +8. Ambien 10 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed for insomnia. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Crohn's Flare +Fevers +Dehydration +Sinus Tachycardia +Fluid collection +. +Secondary: +depression, Crohn's dz + + +Discharge Condition: +Stable. +Tolerating regular diet. +Pain well controlled with oral medications + + +Discharge Instructions: +Please call your doctor or return to the ER for any of the +following: +* If you are vomiting and cannot keep in fluids or your +medications. +* You are getting dehydrated due to continued vomiting, +diarrhea or other reasons. Signs of dehydration include dry +mouth, rapid heartbeat or feeling dizzy or faint when standing. +* You see blood or dark/black material when you vomit or have a +bowel movement. +* Your pain is not improving within 8-12 hours or not gone +within 24 hours. Call or return immediately if your pain is +getting worse or is changing location or moving to your chest or + +back. +*Avoid driving or operating heavy machinery while taking pain +medications. +* You have shaking chills, or a fever greater than 101.5 (F) +degrees or 38(C) degrees. +* Any serious change in your symptoms, or any new symptoms that +concern you. +* Please resume all regular home medications and take any new +meds +as ordered. +* Continue to ambulate several times per day. +. +Incision Care: +-Your steri-strips will fall off on their own. Please remove any +remaining strips 7-10 days after surgery. +-You may shower, and wash surgical incisions. +-Avoid swimming and baths until your follow-up appointment. +-Please call the doctor if you have increased pain, swelling, +redness, or drainage from the incision sites. +. + + +Followup Instructions: +1. Please call Dr.[**Name (NI) 3377**] office, [**Telephone/Fax (1) 160**], to make a +follow up appointment in [**11-20**] weeks. +. +Scheduled Appointments : +Provider: [**Name10 (NameIs) **] RM 3 [**Name10 (NameIs) **]-PREADMISSION TESTING Date/Time:[**2123-5-3**] +8:30 +Provider: [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 250**] +Date/Time:[**2123-5-18**] 8:40 +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 2163**], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2123-6-21**] 10:00 + +NEITHER DICTATED NOR READ BY ME + + +Completed by:[**2123-5-25**]",12,2123-04-26 20:13:00,2123-05-25 14:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,INTRAABDOMINAL ABSCESS," +31f here with long-standing refractory crohns presenting with a +severe flare and intravascular depletion. +. +# abdominal pain/surgical abdomen: most likely [**12-21**] crohns flare +given findings on ct (multiple tiny pockets of extraluminal air, +worsening bowel wall thickening consistent with crohns flare). +other less likely etiologies include perforated ulcer (given +chronic steroid use). evaluated by surgery in ed and upon +admission to [**hospital unit name 153**]. received iv vancomycin/zosyn. per gi to +continue hydrcortisone 100 mg qdaily. ngt placed. foley in +place. strict npo, serial abd exam. +- npo +- serial abdominal exam +-antibiotics +-hydrocortisone 100mg daily +- morphine 2-4mg iv prn abdominal pain +. +# sinus tachycardia: in the setting of intravascular depletion, +crohns flare, abdominal pain. +- ivf resuscitation +- pain control with morphine 2-4mg iv prn +- broad spectrum abx + +. +the patient was transferred to [**hospital ward name 1950**] 5 she was made npo with +ivf/foley/ivmeds/abx. she was febrile to 102.9 with increased +pain. her pain medication was changed from morphine to dilaudid +with good effect. the patient also had a repeat ct scan showing +a fluid collection in her abdomen. she was taken to ir to have a +drain place. scant thick pus aspirated and cultured. +. +a picc line was placed and the patient was started on tpn with +bowel rest. she continued to spike temps to 103.0. multiple +fever workups were done including bcx, ucx and cxr all negative +for infection. she had multiple ct scans done indicating +abcesses. she was taken to ir for drain placement, 2 drains +placed for a total of 4 drains. +. +despite the drain placements the patient continued to spike +temps to 104.6 on hd 19 requiring a cooling blanket. she was +than pre-opd and taken to the or for ex-lap, washout and drain +placement. +. +she returned to the floor. she was maintained as npo, tpn was +continued along with a pca, ivf, abx. infectious disease was +also consulted to recommend treatment. pod 1 the patient was +afebrile. however she continued to spike daily fevers there on +out. id continued to follow the patient adjust antibiotics as +needed. +. +the patient c/o of severe pain and the pain service was +consulted. she was started on a fentynal patch and po dilaudid +with good effect. at discharge the patient no longer needed the +fentynal patch, her pain was well controlled with dilaudid. her +tpn was cycled and with the return of bowel function and flatus +her diet was advanced from sips to regular. her tpn was d/cd +once she tolerated regular diet. +all of her drains were d/cd prior to d/c. the patient was +encouraged to have ensure with all meals. all d/c paperwork was +reviewed with the patient and all questions answered. she will +follow up with dr. [**last name (stitle) 1120**] in [**11-20**] weeks. + + ","PRIMARY: [Regional enteritis of small intestine with large intestine] +SECONDARY: [Peritoneal abscess; Other candidiasis of other specified sites; Peritonitis (acute) generalized; Anorexia nervosa; Pulmonary collapse; Unspecified pleural effusion; Streptococcus infection in conditions classified elsewhere and of unspecified site, other streptococcus; Arthropathy associated with gastrointestinal conditions other than infections; Obsessive-compulsive disorders; Dehydration; Iron deficiency anemia, unspecified; Other acute pain; Other chronic pain; Abdominal pain, right lower quadrant; Abdominal pain, left upper quadrant; Other specified cardiac dysrhythmias; Dysthymic disorder; Personal history of tobacco use; Long-term (current) use of steroids]" +40577,144014.0,18944,2144-12-23,18943,135411.0,2144-12-04,Discharge summary,"Admission Date: [**2144-11-8**] Discharge Date: [**2144-12-4**] + +Date of Birth: [**2092-8-6**] Sex: M + +Service: SURGERY + +Allergies: +Zestril + +Attending:[**First Name3 (LF) 4691**] +Chief Complaint: +motorcycle trauma with hemodynamic instability + +Major Surgical or Invasive Procedure: +[**11-8**] exploratory laparotomy, washout of BL arms, R groin and +repair R knee degloving injury +[**11-9**] washout of R groin, removal of lap band port, ORIF R elbow +[**11-10**] ORIF L elbow +[**11-11**] Trach, open placement of G-tube, removal gastric band + +History of Present Illness: +52yo M on motorcycle who rearended a car and was then struck +from behind at 70mph. Initially brought to [**Hospital 189**] Hospital where +noted to have BL UE fractures, hypotensive, and thus intubated +and transferred to [**Hospital1 18**] for further eval and mgmt. + +Past Medical History: +motorcycle trauma with BL open Monteggia fractures, R knee +degloving injury, hypotension, facial laceration +acute on chronic renal failure (previous baseline creatinine +2.0, now 2.7) +hypernatremia +anemia of chronic renal disease +morbid obesity s/p lap gastric band ([**Doctor Last Name **]) [**12-25**], now removed +DM2 +CAD s/p stenting x2 ([**12-19**] at [**Hospital1 1774**]) +HTN +hypercholesterolemia +CHF +OSA +Back Pain +Psoriatic Arthritis +L shoulder pain + +Social History: +Lives with wife, 3 children. On disability, former truck driver. +Former smoker, quit [**9-24**] after 80 pack year history. No current +ETOH, former heavy drinker. No illicits. + + +Family History: +Father - leukemia, [**Name2 (NI) 32071**] heart disease. Mother - [**Name (NI) 2320**]. +Sister - [**Name (NI) 2320**]. + +Physical Exam: +50, 81/40, 18, 100% +Intubated. Moving legs BL, withdrawal to pain +Face swollen +BL breath sounds +L->midline abdominal laceration. FAST negative. +BL elbow lacerations with open fractures +R knee degloving injury. + +Pertinent Results: +[**2144-12-4**] 01:36AM BLOOD WBC-7.4 RBC-2.62* Hgb-7.8* Hct-23.4* +MCV-89 MCH-29.8 MCHC-33.4 RDW-13.7 Plt Ct-174 +[**2144-12-4**] 01:36AM BLOOD PT-17.6* PTT-34.0 INR(PT)-1.6* +[**2144-12-4**] 01:36AM BLOOD Glucose-46* UreaN-90* Creat-2.7* Na-139 +K-5.7* Cl-106 HCO3-26 AnGap-13 +[**2144-12-4**] 06:06AM BLOOD K-5.4* +[**2144-12-4**] 01:36AM BLOOD Calcium-9.1 Phos-5.8* Mg-3.0* +[**2144-11-26**] 02:33AM BLOOD calTIBC-160* Ferritn-978* TRF-123* +[**2144-11-8**] 08:22PM BLOOD ASA-NEG Ethanol-69* Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG + +Brief Hospital Course: +52yo M brought to [**Hospital1 18**] by ambulance as a trauma basic. +Evaluation in trauma bay demonstrated persistent hypotension +which mildly improved with IVF resuscitation and 3u PRBC +transfusion, despite a negative FAST examination. A DPL was +attempted and was not confirmatory for the absence of +hemoperitoneum. Accordingly, he was brought to the operating +room for exploratory laparotomy which did not reveal an +intraabdominal injury, as well as washout/debridement of his BL +UE injuries by orthopedics; please see each operative report for +further details. Post-operatively he was brought to the TSICU, +intubated and sedated, and hemodynamically stable. The +remainder of his hospital course will be summarized by system: +. +Neuro: Sedation and analgesia provided by drips during +intubation, weaned after tracheotomy. Currently off drips and +managed with intermittent ativan and oxycodone. +. +CV: Pressors were weaned off quickly after initial operation. He +was hemodynamically stable throughout the remainder of his +hospital stay. On lopressor, norvasc, and imdur for HTN, with +intermittent hydralazine. +. +Resp: The vent settings were progressively weaned, slowed by +volume overload from his perioperative resuscitation which was +limited due to his acute-on-chronic renal failure. He was +extubated on HD 10 but required reintubation that same day. He +was trach'd on HD 13 because of failure to wean/extubate. Vent +was progressively weaned, currently on CPAP/PS 35%, PS between 5 +and 10, and PEEP 5. He tolerates trach collar intermittently. +He did have an enterobacter PNA on HD 15, resistant to +Zosyn/cephalosporins, which was treated with a 7-day course of +Cipro IV and Tobramycin inhaled. +. +GI: No intraabdominal injuries identified at laparotomy. The +port for the gastric band was exposed by the abdominal +laceration and removed on HD 2 by Dr. [**Last Name (STitle) **]. The remainder of +the gastric band was removed at the time of surgical g-tube +placement on HD 13. Tube feeds were begun the following day. +Has been on a bowel regimen with regular stools. +. +GU/Renal: Pt has chronic renal insufficiency, which flared to +acute renal failure after attempted diuresis. Initially +creatinine 2.1, peaked at 5.1, and settled at 2.7. Renal +consulted; presumably ATN. Vascular surgery consulted for +possible renal artery stenosis -- considered angiogram with +carbon dioxide contrast but deferred as renal function began to +improve. Hypernatremia of 155 treated with extensive FW +administration, resistant to improvement by both G-tube and IV, +now resolved and beginning to reduce the FW administration. One +additional attempt at diuresis on HD 25 caused sl increase in +creatinine and further attempts have been put on hold. +. +Heme: Pt was transfused in the trauma bay and OR. He remained +anemic with Hct in the low 20's over the next few days despite +continued transfusions, presumably from chronic renal failure. +Because he was hemodynamically stable, further transfusions were +not given. Ultimately he received 19 units of PRBC, 4u of Plts, +and 7u of FFP over the course of his hospitalization. +. +ID: Cellulitis of RUE surgical site treated with Kefzol for ~1 +week. Enterobacter PNA on HD 15, resistant to +Zosyn/cephalosporins, which was treated with a 7-day course of +Cipro IV and Tobramycin inhaled. +. +Endo: Glycemic control managed by [**Last Name (un) **] consult, initially for +hyperglycemia and lately for hypoglycemia. Insulin gtt +initially required, now controlled with SQ by sliding scale and +long-term doses. +. +MSK: BL open Monteggia fractures washed out on HD 1, R fixed +with ORIF on HD 2, L fixed with ORIF on HD 3. Cellulitis of R +treated with Kefzol. R groin laceration washed out on HD 1 by +GenSurg, WTD dsg applied, and re-washed out on HD 2 with +placement of VAC. Currently receiving WTD to R groin. R knee +degloving injury was washed out by ortho on HD 1, wrapped, and +stitched eventually removed. Currently scabbed. C-spine and +TLS-spine were cleared radiographically. Nasal laceration at L +alar was repaired by plastics, with sutures removed prior to +discharge. +. +Proph: Hep SQ TID. GI prophylaxis ceased upon tolerance of TF. + +Medications on Admission: +plavix 75', bASA', lopressor 25'', imdur 30', cozaar 100', lasix +80'', lipitor 80', zetia 10', gemfibrozil 600'', amaryl 2'', +novolin 14am/10pm, [**Last Name (un) **], celexa 20', flonase 50'', vit D +50000qwk + +Discharge Medications: +1. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) mL +Injection TID (3 times a day). +2. Chlorhexidine Gluconate 0.12 % Mouthwash Sig: Fifteen (15) ML +Mucous membrane [**Hospital1 **] (2 times a day). +3. Polyvinyl Alcohol-Povidone 1.4-0.6 % Dropperette Sig: [**2-19**] +Drops Ophthalmic PRN (as needed). +4. Albuterol 90 mcg/Actuation Aerosol Sig: Six (6) Puff +Inhalation Q2H (every 2 hours) as needed. +5. Bacitracin Zinc 500 unit/g Ointment Sig: One (1) Appl Topical +QID (4 times a day) as needed. +6. Docusate Sodium 50 mg/5 mL Liquid Sig: Ten (10) mL PO BID (2 +times a day). +7. Bisacodyl 10 mg Suppository Sig: One (1) Suppository Rectal +DAILY (Daily) as needed. +8. Triamcinolone Acetonide 0.025 % Cream Sig: One (1) Appl +Topical [**Hospital1 **] (2 times a day). +9. Acetaminophen 160 mg/5 mL Solution Sig: Twenty (20) mL +mL PO Q6H (every 6 hours) as needed. +10. Nystatin 100,000 unit/mL Suspension Sig: Five (5) ML PO QID +(4 times a day) as needed. +11. Magnesium Hydroxide 400 mg/5 mL Suspension Sig: Thirty (30) +ML PO Q6H (every 6 hours) as needed. +12. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO BID (2 +times a day). +13. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +14. Calcium Acetate 667 mg Capsule Sig: One (1) Capsule PO TID +W/MEALS (3 TIMES A DAY WITH MEALS). +15. Amlodipine 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +16. Metoprolol Tartrate 50 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +17. Oxycodone 5 mg/5 mL Solution Sig: Ten (10) mL PO Q8H (every +8 hours). +18. Quetiapine 25 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +19. Isosorbide Dinitrate 10 mg Tablet Sig: One (1) Tablet PO TID +(3 times a day). +20. Insulin Glargine 100 unit/mL Solution Sig: 0.25 mL +Subcutaneous at bedtime: 25u of Glargine qday at bedtime. +21. Insulin Regular Human 300 unit/3 mL Insulin Pen Sig: as +directed Subcutaneous four times a day: Sliding Scale: +61-120 mg/dL 0 Units +121-140 mg/dL 4 Units +141-160 mg/dL 6 Units +161-180 mg/dL 8 Units +181-200 mg/dL 10 Units +201-220 mg/dL 12 Units +221-240 mg/dL 14 Units +241-260 mg/dL 16 Units +261-280 mg/dL 18 Units +281-300 mg/dL 20 Units +301-320 mg/dL 22 Units +321-340 mg/dL 24 Units +341-360 mg/dL 26 Units +361-380 mg/dL 28 Units +381-400 mg/dL 30 Units +> 400 mg/dL 32 Units +. +22. Metoclopramide 5 mg/mL Solution Sig: One (1) mL Injection +Q6H (every 6 hours). +23. Hydromorphone 2 mg/mL Solution Sig: 0.25-1 mL Injection Q3H +(every 3 hours) as needed for pain. +24. Lorazepam 2 mg/mL Syringe Sig: 0.25 mL Injection HS (at +bedtime). +25. Lorazepam 2 mg/mL Syringe Sig: 0.25 mL Injection Q8H (every +8 hours) as needed for agitation. +26. Hydralazine 20 mg/mL Solution Sig: 0.5-1 mL Injection Q6H +(every 6 hours) as needed for SBP > 160. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +motorcycle trauma with BL open Monteggia fractures, R knee +degloving injury, hypotension, facial laceration +acute on chronic renal failure (previous baseline creatinine +2.0, now 2.7) +hypernatremia +anemia of chronic renal disease +morbid obesity s/p lap gastric band ([**Doctor Last Name **]) [**12-25**], now removed +DM2 +CAD s/p stenting x2 ([**12-19**] at [**Hospital1 1774**]) +HTN +hypercholesterolemia +CHF +OSA +Back Pain +Psoriatic Arthritis +L shoulder pain + + +Discharge Condition: +stable, on vent via trach, tolerating tube feeds via g-tube. + + +Discharge Instructions: +[**Name8 (MD) **] MD for: fever or chills; nausea, vomiting, constipation, +diarrhea, or abdominal pain; redness, swelling, or drainage from +any incision. + +Wean vent to trach collar as tolerated. + +Tube feeds via G-tube. + +Physical therapy for PROM of BL upper extremities. + +Followup Instructions: +Follow-up with Trauma surgery, Dr. [**Last Name (STitle) **], in 2 weeks. Call +[**Telephone/Fax (1) 6429**] for an appointment. +Follow-up with Orthopedic surgery, Drs. [**Last Name (STitle) 1005**] [**Name5 (PTitle) **] [**Name5 (PTitle) **], +in 2 weeks. Call [**Telephone/Fax (1) 1228**] for an appointment. +Follow-up with Vascular surgery, Dr. [**Last Name (STitle) **], in 2 weeks. +Call [**Telephone/Fax (1) 2625**] for an appointment. +Follow-up with Bariatric surgery, Dr. [**Last Name (STitle) **]. Call [**Telephone/Fax (1) 2723**] +for an appointment. +Follow-up with Nephrology, Dr. [**Last Name (STitle) 4090**], in 2 weeks. Call +[**Telephone/Fax (1) 3637**] for an appointment. +Follow-up with your outpatient primary care physician [**Last Name (NamePattern4) **] 2 +weeks. + + + +",19,2144-11-08 21:58:00,2144-12-04 13:25:00,EMERGENCY,EMERGENCY ROOM ADMIT,REHAB/DISTINCT PART HOSP,MOTOR CYCLE COLLISION," +52yo m brought to [**hospital1 18**] by ambulance as a trauma basic. +evaluation in trauma bay demonstrated persistent hypotension +which mildly improved with ivf resuscitation and 3u prbc +transfusion, despite a negative fast examination. a dpl was +attempted and was not confirmatory for the absence of +hemoperitoneum. accordingly, he was brought to the operating +room for exploratory laparotomy which did not reveal an +intraabdominal injury, as well as washout/debridement of his bl +ue injuries by orthopedics; please see each operative report for +further details. post-operatively he was brought to the tsicu, +intubated and sedated, and hemodynamically stable. the +remainder of his hospital course will be summarized by system: +. +neuro: sedation and analgesia provided by drips during +intubation, weaned after tracheotomy. currently off drips and +managed with intermittent ativan and oxycodone. +. +cv: pressors were weaned off quickly after initial operation. he +was hemodynamically stable throughout the remainder of his +hospital stay. on lopressor, norvasc, and imdur for htn, with +intermittent hydralazine. +. +resp: the vent settings were progressively weaned, slowed by +volume overload from his perioperative resuscitation which was +limited due to his acute-on-chronic renal failure. he was +extubated on hd 10 but required reintubation that same day. he +was trachd on hd 13 because of failure to wean/extubate. vent +was progressively weaned, currently on cpap/ps 35%, ps between 5 +and 10, and peep 5. he tolerates trach collar intermittently. +he did have an enterobacter pna on hd 15, resistant to +zosyn/cephalosporins, which was treated with a 7-day course of +cipro iv and tobramycin inhaled. +. +gi: no intraabdominal injuries identified at laparotomy. the +port for the gastric band was exposed by the abdominal +laceration and removed on hd 2 by dr. [**last name (stitle) **]. the remainder of +the gastric band was removed at the time of surgical g-tube +placement on hd 13. tube feeds were begun the following day. +has been on a bowel regimen with regular stools. +. +gu/renal: pt has chronic renal insufficiency, which flared to +acute renal failure after attempted diuresis. initially +creatinine 2.1, peaked at 5.1, and settled at 2.7. renal +consulted; presumably atn. vascular surgery consulted for +possible renal artery stenosis -- considered angiogram with +carbon dioxide contrast but deferred as renal function began to +improve. hypernatremia of 155 treated with extensive fw +administration, resistant to improvement by both g-tube and iv, +now resolved and beginning to reduce the fw administration. one +additional attempt at diuresis on hd 25 caused sl increase in +creatinine and further attempts have been put on hold. +. +heme: pt was transfused in the trauma bay and or. he remained +anemic with hct in the low 20s over the next few days despite +continued transfusions, presumably from chronic renal failure. +because he was hemodynamically stable, further transfusions were +not given. ultimately he received 19 units of prbc, 4u of plts, +and 7u of ffp over the course of his hospitalization. +. +id: cellulitis of rue surgical site treated with kefzol for ~1 +week. enterobacter pna on hd 15, resistant to +zosyn/cephalosporins, which was treated with a 7-day course of +cipro iv and tobramycin inhaled. +. +endo: glycemic control managed by [**last name (un) **] consult, initially for +hyperglycemia and lately for hypoglycemia. insulin gtt +initially required, now controlled with sq by sliding scale and +long-term doses. +. +msk: bl open monteggia fractures washed out on hd 1, r fixed +with orif on hd 2, l fixed with orif on hd 3. cellulitis of r +treated with kefzol. r groin laceration washed out on hd 1 by +gensurg, wtd dsg applied, and re-washed out on hd 2 with +placement of vac. currently receiving wtd to r groin. r knee +degloving injury was washed out by ortho on hd 1, wrapped, and +stitched eventually removed. currently scabbed. c-spine and +tls-spine were cleared radiographically. nasal laceration at l +alar was repaired by plastics, with sutures removed prior to +discharge. +. +proph: hep sq tid. gi prophylaxis ceased upon tolerance of tf. + + ","PRIMARY: [Open fracture of shaft of ulna (alone)] +SECONDARY: [; Open wound of knee, leg [except thigh], and ankle, with tendon involvement; Acute posthemorrhagic anemia; Injury to other intra-abdominal organs without mention of open wound into cavity, peritoneum; Traumatic shock; Acute kidney failure with lesion of tubular necrosis; Pneumonia due to other gram-negative bacteria; Mechanical complication due to other implant and internal device, not elsewhere classified; Other postoperative infection; Cellulitis and abscess of upper arm and forearm; Hyperosmolality and/or hypernatremia; Other motor vehicle traffic accident involving collision with motor vehicle injuring motorcyclist; Closed dislocation of wrist, unspecified part; Open Monteggia's fracture; Open wound of abdominal wall, lateral, complicated; Morbid obesity; Surgical operation with anastomosis, bypass, or graft, with natural or artificial tissues used as implant causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Bariatric surgery status; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Chronic kidney disease, unspecified; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Surgical operation with implant of artificial internal device causing abnormal patient reaction, or later complication,without mention of misadventure at time of operation; Open wound of nose, unspecified site, complicated; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Congestive heart failure, unspecified; Obstructive sleep apnea (adult)(pediatric); Psoriatic arthropathy]" +43122,168271.0,13574,2101-06-13,13573,180308.0,2101-05-19,Discharge summary,"Admission Date: [**2101-5-12**] Discharge Date: [**2101-5-19**] + + +Service: SURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 1**] +Chief Complaint: +- abdominal pain + +Major Surgical or Invasive Procedure: +- closure/[**Location (un) **] patch for perforated duodenal ulcer + +History of Present Illness: +On admission: +The patient is a [**Age over 90 **]-year-old female who began having +intermittant generalized abdominal pain about 4 days ago. She +had some mild nausea and one episode of small volume emesis, but +she attributes this to her vertigo. Today, her pain increased a +great deal, and became quite sharp and constant and unbearable +to the point that she was crying at home. She was brought to the +ED by EMS for evaluation. Her last BM was earlier today and was +normal. She denies fever +and chills. She does have anorexia, but she says this has been +going on for some months. + + +Past Medical History: +- hypertension +- palpitations +- depression +- vertigo +- COPD/asthma +- hearing loss + +Social History: +- rare social alcohol use, denies T/D +- lives in [**Location **] in senior housing + +Family History: +- non-contributory + +Physical Exam: +Day of Discharge: +Vitals - T:97.9 BP:125/62 HR:83 RR:20 O2sat:98% on 2L NC +FS:113-134 +Gen: NAD, A&O x 3 +CV: irregular, normal rate +Resp: CTAB, no respiratory distress +Abd: soft, not distended, minimal TTP +Incision: C/D/I, no erythema or induration +JP site: dressing C/D/I +L UE: improved erythema, but still with palpable cord + +Pertinent Results: +[**2101-5-12**] CXR: +IMPRESSION: Pneumoperitoneum with bowel perforation better +assessed on CT +abdomen/pelvis performed within the same hour. Large left +diaphragmatic +hernia. Right lung base bronchiectasis may be related to chronic +aspiration. +. +[**2101-5-12**] CT ABD/PELVIS: +IMPRESSIONS: +1. Findings suggest bowel perforation, likely from the region of +the +pylorus/first portion of the duodenum where there is +circumferential wall +thickening and apparent small rent through the anterior wall. +This causes +large pneumoperitoneum and mild-to-moderate ascites. +2. Large, stomach- and colon-containing left diaphragmatic +hernia. +3. Peripheral ground- glass opacities in the right lower lobe +concerning for aspiration. +4. Few scattered sigmoid colonic diverticulae, without definite +diverticulitis, thus making this less likely cause for bowel +perforation. +. +[**2101-5-12**] WBC-7.2 Hgb-11.4 Hct-33.8 Plt Ct-420 +[**2101-5-12**] Neuts-88 Bands-2 Lymphs-2 Monos-5 Eos-2 Baso-1 Atyps-0 +Metas-0 Myelos-0 +[**2101-5-13**] WBC-15.5 Hgb-10.8 Hct-32.5 Plt Ct-458 +[**2101-5-14**] WBC-10.6 Hgb-8.4 Hct-24.9 Plt Ct-374 +[**2101-5-15**] WBC-9.2 Hgb-9.1 Hct-27.2 Plt Ct-378 +[**2101-5-17**] WBC-8.5 Hgb-9.5 Hct-28.5 Plt Ct-349 +. +[**2101-5-18**] Glucose-86 UreaN-10 Creat-0.5 Na-133 K-4.2 Cl-98 +HCO3-29 +[**2101-5-18**] Calcium-7.5 Phos-3.3 Mg-1.9 +. +[**2101-5-12**] PT-15.2 PTT-28.4 INR(PT)-1.3 +[**2101-5-15**] PT-15.3 PTT-30.9 INR(PT)-1.3 +[**2101-5-16**] PT-16.0 PTT-30.2 INR(PT)-1.4 +[**2101-5-17**] PT-17.2 PTT-30.9 INR(PT)-1.6 + +Brief Hospital Course: +*)Duodenal Ulcer +She was taken to the operating room, where a 4mm defect in the +pyloroduodenal area was noted. The defect was repaired and +reinforced with an omental patch; please see the operative +report for full details. Her diet was slowly advanced and on +discharge she was tolerating a regular diet, albeit with the +same decreased appetite she had had for several months as +reported on admission. +. +*)Tachycardia +Her post-operative course was complicated by tachycardia, which +was initially thought to be atrial fibrillation. Cardiology was +consulted and felt that it may be multi-focal tachycardia. She +had been on verapamil as an outpatient, but was started on +diltiazem during her hospitalization for acute rate control. +This was maintained, as verapamil was noted to be more +constipating. On discharge her heartrate was well controlled on +diltiazem. +. +*)Cellulitis +On POD#5 erythema was noted at the site of a prior infiltrated +IV on her left arm. The area was marked and appeared to grow in +size; vancomycin was started with subsequent improvement of the +erythema. She was discharged on a course of Bactrim to complete +7 days of antibiotics, per ID curbside recommendations. +. +*)Disposition +Physical therapists worked with her during her hospital course +and recommended further therapy after discharge. She was +discharged to a rehabilitation facility to continue her +post-operative recovery. Her home medications, with the +exception of verapamil, were re-started shortly after surgery +and were continued during her hospital course. + +Medications on Admission: +- albuterol +- estrogen ring +- Advair +- Atrovent +- meclizine +- Detrol [**Name Prefix (Prefixes) **] +- [**Last Name (Prefixes) 40988**] +- Tylenol prn + +Discharge Medications: +1. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +2. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q4H (every +4 hours) as needed for pain/fever. +3. Calcium Carbonate 500 mg Tablet, Chewable Sig: Two (2) +Tablet, Chewable PO QID (4 times a day) as needed for low +calcium, heartburn. +4. Diltiazem HCl 240 mg Capsule, Sustained Release Sig: One (1) +Capsule, Sustained Release PO DAILY (Daily). +5. Codeine Sulfate 15 mg Tablet Sig: 1-2 Tablets PO Q3H (every 3 +hours) as needed for pain. +6. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Inhalation twice a day. +7. Ipratropium Bromide 17 mcg/Actuation Aerosol Sig: Two (2) +Inhalation twice a day. +8. Bactrim DS 160-800 mg Tablet Sig: Two (2) Tablet PO twice a +day for 4 days. +Disp:16 Tablet(s) Refills:0 + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +Primary: +Perforated duodenal ulcer +Post-op low urine output +RUE cellulitis +. + +Secondary: +HTN, asthma/COPD, L leg cellulitis, occasional palpitations + + +Discharge Condition: +Stable. +Tolerating regular diet. +Pain well controlled with oral medications. + + +Discharge Instructions: +Rehab: +Please call your doctor or return to the ER for any of the +following: +* You experience new chest pain, pressure, squeezing or +tightness. +* New or worsening cough or wheezing. +* If you are vomiting and cannot keep in fluids or your +medications. +* You are getting dehydrated due to continued vomiting, +diarrhea or other reasons. Signs of dehydration include dry +mouth, rapid heartbeat or feeling dizzy or faint when standing. +* You see blood or dark/black material when you vomit or have a +bowel movement. +* Your pain is not improving within 8-12 hours or not gone +within 24 hours. Call or return immediately if your pain is +getting worse or is changing location or moving to your chest or + +back. +*Avoid lifting objects > 5lbs until your follow-up appointment +with the surgeon. +*Avoid driving or operating heavy machinery while taking pain +medications. +* You have shaking chills, or a fever greater than 101.5 (F) +degrees or 38(C) degrees. +* Any serious change in your symptoms, or any new symptoms that +concern you. +* Please resume all regular home medications and take any new +meds +as ordered. +* Continue to ambulate several times per day. +. +Incision Care: +-Your staples can be removed at rehab on [**5-25**] and steri +strips should be applied. +-Steri-strips will fall off on their own. Please remove any +remaining strips 7-10 days after applicaiton +-You may shower, and wash surgical incisions. +-Avoid swimming and baths until your follow-up appointment. +-Please call the doctor if you have increased pain, swelling, +redness, or drainage from the incision sites. +. +Cellulitis (skin infection) of the left arm: +- please take your antibiotics as directed +- if the infection does not continue to improve, an additional +antibiotic may be added (Keflex/cephalexin) +- you will need a set of labs while you are taking Bactrim + +Followup Instructions: +1. Please call Dr.[**Name (NI) 10946**] office to make a follow up +appointment in [**12-24**] weeks. +. +Scheduled Appointments : +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 2385**], MD Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2101-9-26**] 9:20 + + + +Completed by:[**2101-5-19**]",25,2101-05-12 05:21:00,2101-05-19 13:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,PNEUMOPERITONEUM," +*)duodenal ulcer +she was taken to the operating room, where a 4mm defect in the +pyloroduodenal area was noted. the defect was repaired and +reinforced with an omental patch; please see the operative +report for full details. her diet was slowly advanced and on +discharge she was tolerating a regular diet, albeit with the +same decreased appetite she had had for several months as +reported on admission. +. +*)tachycardia +her post-operative course was complicated by tachycardia, which +was initially thought to be atrial fibrillation. cardiology was +consulted and felt that it may be multi-focal tachycardia. she +had been on verapamil as an outpatient, but was started on +diltiazem during her hospitalization for acute rate control. +this was maintained, as verapamil was noted to be more +constipating. on discharge her heartrate was well controlled on +diltiazem. +. +*)cellulitis +on pod#5 erythema was noted at the site of a prior infiltrated +iv on her left arm. the area was marked and appeared to grow in +size; vancomycin was started with subsequent improvement of the +erythema. she was discharged on a course of bactrim to complete +7 days of antibiotics, per id curbside recommendations. +. +*)disposition +physical therapists worked with her during her hospital course +and recommended further therapy after discharge. she was +discharged to a rehabilitation facility to continue her +post-operative recovery. her home medications, with the +exception of verapamil, were re-started shortly after surgery +and were continued during her hospital course. + + ","PRIMARY: [Chronic or unspecified duodenal ulcer with perforation, without mention of obstruction] +SECONDARY: [Unspecified peritonitis; Cellulitis and abscess of upper arm and forearm; Cardiac complications, not elsewhere classified; Other specified disorders of peritoneum; Unspecified essential hypertension; Depressive disorder, not elsewhere classified; Chronic obstructive asthma, unspecified; Tachycardia, unspecified; Surgical operation with anastomosis, bypass, or graft, with natural or artificial tissues used as implant causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Atrial fibrillation]" +43126,132026.0,23429,2124-09-26,23428,124079.0,2124-08-17,Discharge summary,"Admission Date: [**2124-3-1**] Discharge Date: [**2124-8-17**] + +Date of Birth: [**2067-4-22**] Sex: M + +Service: MEDICINE + +Allergies: +Bactrim + +Attending:[**First Name3 (LF) 3913**] +Chief Complaint: +CLL with [**Doctor Last Name 6261**] Transformation, admitted for Allo SCT + +Major Surgical or Invasive Procedure: +Hickmann Placement & Removal +Central Venous Line Placement and removal x3 +PICC Placement and removal x2 +Sigmoidoscopy with biopsy +Paracentesis + +History of Present Illness: +Mr. [**Known lastname **] is a 56-year-old male with history of CLL with P53 +mutation, s/p FCR and PCR, and Campath [**2123-7-9**], with recent new +onset ([**2122-12-21**])left cervical lymph node enlargment which upon +biopsy revealed large cell ([**Doctor Last Name 6261**]) transformation, s/p [**Hospital1 **] +([**Date range (1) 60068**]), s/p ESHAP ([**Date range (1) 35870**]/09) ([**Date range (1) 60070**]) admitted now +for an ablative Cytoxan/Busulfan matched ([**7-27**]) unrelated donor +peripheral stem cell transplant. +. +The patient reports fatigue and anorexia since previous +admission with decreased taste sensation. He is otherwise +feeling well. On review of systems, he denies any fever, chills, +nausea, vomiting, chest pain, SOB, diarrhea, constipation, +dysuria, abdominal pain, weakness, numbness, or tingling. He +reports anxiety and fear entering transplant, but he has +accepted that it is the next step in his therapy and he is +ready. + +Past Medical History: +Past Medical History: +Hypertension +Hypercholesterolemia (diet controlled) +S/p tonsillectomy +CLL (see below) +. +Past Oncologic History (Per [**Hospital **] Clinic Note): +Pt presented with his disease back in [**10/2119**] with an elevated +white count and LDH. He was without any splenomegaly or any +cytopenias at that time. He did have some bulky lymphadenopathy. +Over the course of six months, his white count began to rise and +essentially doubled to approximately 130,000 with a rising in +his LDH of up to 1400, and he also was noted to have worsening +palpable lymphadenopathy. He then completed four cycles of FCR +therapy, which he completed back in 09/[**2119**]. He had an excellent +response to therapy and was monitored off treatment for +approximately two years. He then presented in [**7-/2122**] with a +rising white count, approximately 50% lymphocytes, +and a mildly elevated LDH. He also had some mild worsening +palpable lymphadenopathy. He then received four cycles of PCR, +but did not have much in the way of response and his treatment +regimen was switched to R-CVP of which he received two cycles. +He did again not have a significant response, though continued +to have an excellent performance status, and he was ultimately +switched to Campath therapy. He did have resolution of his +lymphocytosis, and his white count has come down nicely, but did +not have much in the way of response in terms of reducing his +bulky lymphadenopathy. He had received chemotherapy initially +through 06/[**2122**]. We had decided to observe him off treatment, +and ultimately, we had decided to move forward with an +allogeneic stem cell transplant; however, back at the end of the +summer, his donor had backed out. He also had return of his +disease, and we reinitiated Campath regimen. This, however, +ultimately was cut short on [**2123-7-7**] due to question of an +infection versus PE for which he was ruled out. He has been +followed closely by ID and has been treated on Augmentin since +that time through therapy. He then was restarted back on Campath +and completed six weeks of treatment dose as previously his +cycles have been interrupted. He again had normalization of his +white count and also no longer had any lymphocytosis. However, +he again did not have much in the way of significant response to +his lymphadenopathy. He then eventually had developed an +enlarging left cervical node which was biopsied and was found to +have [**Doctor Last Name **] transformation. He was admitted on [**2124-1-5**] for +[**Hospital1 **]. This [**Hospital1 **] was overall well tolerated. He completed his +first course of ESHAP on [**2124-2-2**], and tolerated this well. +. +Four cycles of FCR (Fludarabine, Cytoxan, +Rituxan) completed on [**2120-8-15**], four cycles of PCR +(Pentostatin, Cytoxan, Rituxan) completed on [**2122-10-1**], two +cycles of R-CVP completed on [**2123-3-11**], Campath treatment +subcutaneously initiated on [**2123-4-14**] and stopped on [**2123-4-30**], +reinitiated on [**2123-6-23**] and stopped on [**2123-7-7**], restarted +on [**2123-10-11**] and completed approximately six weeks of therapy +which he completed on [**2123-12-3**]. Reinitiated therapy due to +[**Doctor Last Name 6261**] transformation with [**Hospital1 **] treatment (Continuous +infusion of etoposide, Adriamycin, and Vincristine on days [**11-21**], +Oral prednisone on days [**11-22**], and Cytoxan on day 5) in 02/[**2123**]. +D/t inadequate disease response from [**Hospital1 **] regimen was switched +to ESHAP (Bolus of Etoposide on days [**11-21**], Cisplatin continuous +infusion on days [**11-21**], Methylprednisolone IV on days [**11-22**], +Cytarabine 2g/m2 IV over 2 hours on day 5 only). + +Social History: +Has been married for 30 years. He works as a software engineer. +He does not smoke and drinks occasional alcohol He has one +daughter who is 20-years-old. + + +Family History: +Notable for father who died of prostate cancer, with question of +lung involvement at the end. His mother had a history of MS and +one of his brothers is obese. An uncle with pancreatic cancer +and an aunt with breast cancer. + + +Physical Exam: +ON ADMISSION: +VS- 97.1 114/70 80 18 98%@RA +Gen: awake, alert, no acute distress, pleasant +HEENT: mucous membranes moist, always with a different [**Location (un) 86**] +sports hat, today Bruins. +Neck: Non-tender, neck supple, no JVD, no thyromegaly +CV: S1 & S2 regular without murmur +Lungs: Clear to auscultation bilaterally, no +wheezes/rales/rhonchi +Abd: soft, non-tender or distended, no HSM, BS present +Ext: No edema, 2+ DP pulses bilaterally +Neuro: AOx3, CN2-12 intact grossly, strength 5/5 diffusely, +sensation intact diffusely, coordination intact bilaterally. +FTN/HTS intact, negative Romberg's sign. + +ON DISCHARGE: +T: 97.0 BP: 119/92 HR: 86 RR: 18 SP02: 98%RA +General: Quite, slow movements, no acute distress +HEENT: Moist mucous membranes, no palpable LAD, neck is supple +CARDIAC: Regular rate and rhythm; normal S1 and S2 +RESP: Clear to auscultation bilaterally; no wheezes, rales, +rhonchi +ABDOMEN: +BS, non-tender, non-distended +EXTREMITY: 1+ edema bilaterally; full range of movement +SKIN: Slightly ashen/icteric + +Pertinent Results: +Please note, there are 5 months worth of labs in our system. +Please find below the admission labs, and below them, the +discharge labs. +. +ADMISSION LABS: +[**2124-3-1**] 09:25AM BLOOD WBC-14.0* RBC-3.19* Hgb-10.0* Hct-28.0* +MCV-88 MCH-31.2 MCHC-35.5* RDW-19.3* Plt Ct-117*# +[**2124-3-1**] 09:25AM BLOOD Neuts-33* Bands-2 Lymphs-55* Monos-5 +Eos-0 Baso-1 Atyps-1* Metas-3* Myelos-0 +[**2124-3-1**] 09:25AM BLOOD Hypochr-NORMAL Anisocy-2+ Poiklo-NORMAL +Macrocy-1+ Microcy-1+ Polychr-1+ +[**2124-3-1**] 09:25AM BLOOD PT-12.0 INR(PT)-1.0 +[**2124-3-1**] 09:25AM BLOOD Gran Ct-5320 +[**2124-3-1**] 09:25AM BLOOD UreaN-23* Creat-1.1 Na-147* K-4.1 Cl-106 +HCO3-28 AnGap-17 +[**2124-3-1**] 09:25AM BLOOD ALT-27 AST-33 LD(LDH)-604* AlkPhos-103 +TotBili-0.3 DirBili-0.1 IndBili-0.2 +[**2124-3-1**] 09:25AM BLOOD Calcium-9.1 Phos-3.2 Mg-1.6 UricAcd-4.5 +. +DISCHARGE LABS: +Na 131, K 3.7, Cl 101, HC03 18 (stable), BUN 24, Cr. 0.5, +Glucose 172, WBC 6.7, Hgb 9.0, Hct 26.9, Plt 95, Ca 8.2, Mg 1.9, +Phos 2.2. LFTS (trending down) ALT 214, AST 93, LDH 668, Alk +Phos 421. +Urine culture [**8-14**]: <10,000 organisms. U/A: Bili small, +bacteria few (most likely contaminated), protein trace, glucose +300, nitrates negative, leukocytes negative. +Other results: +. +Last CMV VL [**2124-8-14**] Negative. +. +ID RESULTS: +-Cdiff negative x4 since [**6-25**] +-[**2124-7-22**] cryptococcal Ag negative +-[**2124-7-20**] Peritoneal fluid negative, Gstain and Cx, Fungal, +anaerobes, AFB all negative +-[**2124-7-14**] CSF negative Gstain, Cx, Crypto, fungal, Ag +-[**2124-7-12**] stool Cx all negative +--VRE bacteremia, s/p linezolid x 2 weeks +- Strep milleri bacteremia, treated, and resolved, TTE [**4-21**] no +vegetation. There is a note that HHV6 was positive at the same +time as patient developed evanescent rash, which was attributed +to HHV6. Repeat serum viral load was negative a week later. +-BK viruria >390 million ([**4-24**]) with bladder spasms, but then +symptoms resolved. +. +Last positive Cx's we have on record are: +Final [**2124-5-17**]: ENTEROCOCCUS FAECIUM. +IDENTIFICATION AND SENSITIVITIES PERFORMED ON CULTURE # [**Numeric Identifier 60071**] + [**2124-5-11**]. +Anaerobic Bottle Gram Stain (Final [**2124-5-14**]): + GRAM POSITIVE COCCI IN CHAINS. +. +Aerobic Bottle Gram Stain (Final [**2124-5-15**]): + GRAM POSITIVE COCCI. + IN PAIRS AND CHAINS. +. +Culture taken from colon: +Time Taken Not Noted Log-In Date/Time: [**2124-5-10**] 6:22 pm + TISSUE COLON. + NO POLYMORPHONUCLEAR LEUKOCYTES SEEN. + 1+ (<1 per 1000X FIELD): GRAM POSITIVE COCCI. + IN PAIRS. + + TISSUE (Final [**2124-5-13**]): + ENTEROCOCCUS SP.. SPARSE GROWTH. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + ENTEROCOCCUS SP. + | +AMPICILLIN------------ =>32 R +LINEZOLID------------- 2 S +PENICILLIN G---------- =>64 R +VANCOMYCIN------------ =>32 R + + ANAEROBIC CULTURE (Final [**2124-5-16**]): + BACTEROIDES FRAGILIS GROUP. SPARSE GROWTH. + BETA LACTAMASE POSITIVE. + + ACID FAST CULTURE (Final [**2124-7-10**]): NO MYCOBACTERIA +ISOLATED. + + ACID FAST SMEAR (Final [**2124-5-11**]): + NO ACID FAST BACILLI SEEN ON DIRECT SMEAR. + + FUNGAL CULTURE (Final [**2124-5-26**]): NO FUNGUS ISOLATED. + +[**2124-4-15**] 12:05 pm BLOOD CULTURE + + **FINAL REPORT [**2124-4-18**]** + + Blood Culture, Routine (Final [**2124-4-18**]): + STREPTOCOCCUS ANGINOSUS (MILLERI) GROUP. FINAL +SENSITIVITIES. + CLINDAMYCIN RESISTANT @ > 2MCG/ML. + ERYTHROMYCIN RESISTANT @>4MCG/ML. + Sensitivity testing performed by Sensititre. + + SENSITIVITIES: MIC expressed in +MCG/ML + +_________________________________________________________ + STREPTOCOCCUS ANGINOSUS (MILLERI) +GROUP + | +CLINDAMYCIN----------- R +ERYTHROMYCIN---------- R +PENICILLIN G---------- 0.06 S +VANCOMYCIN------------ 1 S + + Anaerobic Bottle Gram Stain (Final [**2124-4-16**]): + REPORTED BY PHONE TO [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] @ 1035AM [**2124-4-16**]. + GRAM POSITIVE COCCI IN CHAINS. + +The following are significant reports from the last 5 months. +However, due to volume of reports, this list is not inclusive. + +[**2124-7-21**] CXR +FINDINGS: In comparison with study of [**7-12**], there is a slightly +better +inspiration with continued enlargement of the cardiac silhouette +and widening of the mediastinum due to extensive mediastinal +lipomatosis. Lungs are clear and there is no vascular +congestion. + +CENTRAL CATHETER REMAINS IN PLACE. + +[**2124-7-19**] Doppler u/s abdomen +FINDINGS: Transabdominal ultrasound with Doppler demonstrates +patent hepatic veins including the right middle and left hepatic +veins. There is appropriate direction of flow. No thrombus is +seen. Patient evaluation is limited due to patient's inability +to breath-hold. The main portal vein was seen to be patent with +appropriate direction of flow on the earlier study. The hepatic +artery was not visualized. Moderate ascites throughout the +abdomen, unchanged from prior study. + +IMPRESSION: Limited evaluation. Hepatic veins are patent with +appropriate +direction of flow with no thrombus seen. + +[**2124-7-18**] CT abdomen pelvis + + +FINDINGS: The lung bases demonstrate increased atelectasis when +compared to prior study of [**2124-5-11**]. In addition, there are +bilateral pleural +effusions, left greater than right, both slightly increased in +size since the prior study. The heart size is normal. The +spleen, gallbladder, pancreas, adrenal glands, stomach are +within normal limits. Both kidneys demonstrate parapelvic cysts +bilaterally. Otherwise, the kidneys both enhance and excrete +contrast symmetrically bilaterally. A small hyperdensity is +noted within the right lobe of the liver (2:22), unchanged in +size and appearance since at least [**2124-3-17**]. Multiple small +retroperitoneal and mesenteric lymph nodes are again noted, none +meeting CT criteria for pathologic enlargement. There is no free +air. + +There is a moderate amount of ascites, which has increased in +amount since the CT of [**5-11**]. In addition, there is a +significant amount of soft tissue edema throughout the entire +subcutaneous tissues of the abdomen, which has greatly increased +also since the prior study. + +There is persistent mild bowel wall thickening at the ileum that +apperas +moreso in the terminal ileum, not significantly changed. Fatty +change in the wall of the terminal ileum also is stable. In some +of the areas of wall thickening there is striated enhancement, +but the mucosal enhancement is only mildly increased and this is +in collapsed bowel. No distended bowel shows wall thickening +with striated enhancement. There are mildly dilated loops of +jejunum and proximal ileum without a transition pint. Previously +described possible edema of the gastric antrum/pylorus is not +apparent on today's study. + +CT OF THE PELVIS WITH IV CONTRAST: The rectum and prostate are +within normal limits. Air within the bladder is likely due to +recent placement of a Foley catheter. A large amount of free +fluid is noted within the pelvis, increased since the prior +study. There is no pelvic or inguinal lymphadenopathy. There is +a small left sided fat containing inguinal hernia. + +BONE WINDOWS: No suspicious osseous lesions are seen. Left +eighth rib +deformity consistent with old healed fracture, unchanged. + +IMPRESSION: +1. Increased ascites within the abdomen and pelvis. Bilateral +pleural +effusions, left greater than right, also slightly increased +since the prior study. Anasarca. + +2. Persistent mild ileal wall thickening and with fatty +deposition in the +terminal ileal wall, unchanged. No convinving active ileitis at +this time +with the findings likely reflecting chronic changes from graft +versus host +disease. No obstruction, but likely mild small bowel ileus. + +[**2124-7-15**] MRI head +FINDINGS: The diffusion images, which are adequate for +interpretation, +demonstrate no acute infarct. There is no mass effect or midline +shift. The remaining images are limited by motion demonstrate no +obvious midline shift or hydrocephalus. There are no obvious +areas of enhancement seen on motion limited axial images but +evaluation is limited. Subtle areas of high signal on both basal +ganglia region on post-gadolinium axial images are artifactual +from pulsation artifacts. + +IMPRESSION: Limited study due to motion. Diffusion images which +are adequate for interpretation demonstrate no acute infarct. +Other images, which are limited demonstrate no obvious +abnormalities, but for better evaluation if clinically +indicated, a repeat study can be obtained with sedation. + +[**2124-7-3**] RUE U/S +FINDINGS: + +RIGHT UPPER EXTREMITY VENOUS ULTRASOUND: + +The right internal jugular vein is patent. The proximal right +subclavian vein at the level of the internal jugular vein is +patent. Just distal to the internal jugular vein, the subclavian +vein is thrombosed. The vein is +distended with echogenic clot and demonstrates absence of flow +and +compressibility. The axillary vein is now only partially +thrombosed, with +minimal flow seen around the echogenic clot. There is partial +compressibility. The basilic vein is patent. + +One of the paired brachial veins remains thrombosed with +echogenic clot +distending the lumen and absence of flow and compressibility. +The other +brachial vein is patent. The cephalic vein remains completely +thrombosed +without compressibility or flow. + +The left subclavian vein is patent. + +IMPRESSION: + +1. Interval improvement in degree of the right upper extremity +thrombosis, +now with only partial clot in the right axillary vein, and flow +in the basilic +vein. + +2. Persistent thrombosis of the superficial veins of the right +upper +extremity, with thrombosis of one of the paired brachial veins +and the +axillary vein. + +[**2124-6-15**] ECHO +Findings +LEFT ATRIUM: Mild LA enlargement. + +RIGHT ATRIUM/INTERATRIAL SEPTUM: Normal RA size. + +LEFT VENTRICLE: Normal LV wall thickness. Small LV cavity. +Overall normal LVEF (>55%). No resting LVOT gradient. No VSD. + +RIGHT VENTRICLE: Normal RV chamber size and free wall motion. + +AORTA: Normal aortic diameter at the sinus level. Normal +ascending aorta diameter. Normal aortic arch diameter. + +AORTIC VALVE: Normal aortic valve leaflets (3). No AS. No AR. No +masses or vegetations on aortic valve, but cannot be fully +excluded due to suboptimal image quality. + +MITRAL VALVE: Mildly thickened mitral valve leaflets. No MVP. No +masses or vegetations on mitral valve, but cannot be fully +excluded due to suboptimal image quality. Normal mitral valve +supporting structures. No MS. Mild (1+) MR. LV inflow +uninterpretable due to tachycardia and/or fusion of spectral +Doppler E and A waves + +TRICUSPID VALVE: Normal tricuspid valve leaflets with trivial +TR. No masses or vegetations are seen on the tricuspid valve, +but cannot be fully excluded due to suboptimal image quality. +Normal tricuspid valve supporting structures. No TS. Normal PA +systolic pressure. + +PULMONIC VALVE/PULMONARY ARTERY: Normal pulmonic valve leaflet. +No PS. Physiologic PR. No vegetation/mass on pulmonic valve. +Normal main PA. No Doppler evidence for PDA + +PERICARDIUM: No pericardial effusion. + +GENERAL COMMENTS: Suboptimal image quality - poor echo windows. + +Conclusions +The left atrium is mildly dilated. Left ventricular wall +thicknesses are normal. The left ventricular cavity is small. +Overall left ventricular systolic function is normal (LVEF 70%). +There is no ventricular septal defect. Right ventricular chamber +size and free wall motion are normal. The aortic valve leaflets +(3) appear structurally normal with good leaflet excursion and +no aortic regurgitation. No masses or vegetations are seen on +the aortic valve, but cannot be fully excluded due to suboptimal +image quality. The mitral valve leaflets are mildly thickened. +There is no mitral valve prolapse. No masses or vegetations are +seen on the mitral valve, but cannot be fully excluded due to +suboptimal image quality. Mild (1+) mitral regurgitation is +seen. No masses or vegetations are seen on the tricuspid valve, +but cannot be fully excluded due to suboptimal image quality. +The estimated pulmonary artery systolic pressure is normal. No +vegetation/mass is seen on the pulmonic valve. There is no +pericardial effusion. + +Compared with the findings of the prior study (images reviewed) +of [**2124-5-12**], no major change. + +IMPRESSION: Suboptimal image quality. No obvious vegetations +seen + +If clinically suggested, the absence of a vegetation by 2D +echocardiography does not exclude endocarditis. + +[**2124-7-21**] FLOW CYTOMETRY PERIPHERAL BLOOD + +FLOW CYTOMETRY REPORT + +FLOW CYTOMETRY IMMUNOPHENOTYPING + +The following tests (antibodies) were performed: HLA-DR, FMC-7, +Kappa, and CD antigens 3, 5, 10, 19, 20, 23, 38, 45. + + +RESULTS: + + Three color gating (CD45 versus light scatter) is used to +determine population of interest. + + B cells are extremely scant in number, however, appear +polytypic. + + T cells comprise 90% of lymphoid gated events. + + INTERPRETATION + + Non-specific T cell dominant lymphoid profile; diagnostic +immunophenotypic features of involvement by a non-Hodgkin B-cell +lymphoma are not seen in specimen. Correlation with clinical +findings is recommended. Flow cytometry immunophenotyping may +not detect all lymphomas due to topography, sampling or +artifacts or sample preparation. + +[**2124-7-20**] FLOW CYTOMETRY ASCITES +FLOW CYTOMETRY REPORT + +FLOW CYTOMETRY IMMUNOPHENOTYPING + +The following tests (antibodies) were performed: HLA-DR, FMC-7, +Kappa, Lambda, and CD antigens 3, 5, 10, 19, 20, 23, 38, 45. + +RESULTS: + +Three color gating is performed (light scatter vs. CD45) to +optimize lymphocyte yield. + +B cells are scant in number precluding evaluation of clonality. + +T cells comprise 90% of lymphoid gated events. + +INTERPRETATION + +Non-specific T cell dominant lymphoid profile; diagnostic +immunophenotypic features of involvement by a non-Hodgkin B-cell +lymphoma are not seen in specimen. Correlation with clinical +findings is recommended. Flow cytometry immunophenotyping may +not detect all lymphomas due to topography, sampling or +artifacts or sample preparation. + +[**2124-6-26**] FLOW CYTOMETRY OF CSF FLUID +The following tests (antibodies) were performed: Kappa, Lambda, +and CD antigens 19, 45. +RESULTS: + +Three color gating is performed (light scatter vs. CD45) to +optimize lymphocyte yield. + +B cells are scant in number precluding evaluation of clonality. + +T cells comprise 99% of lymphoid gated events. + +INTERPRETATION + +Non-specific T cell dominant lymphoid profile; diagnostic +immunophenotypic features of involvement by lymphoma are not +seen in specimen. Correlation with clinical findings is +recommended. Flow cytometry immunophenotyping may not detect all +lymphomas as due to topography, sampling or artifacts of sample +preparation. + +[**2124-5-29**] SKIN BX +DIAGNOSIS: +1. Skin, right forearm, biopsy (A-B): + +Interface and superficial perivascular dermatitis with marked +dyskeratosis, dermal melanophages, and extravasated +erythrocytes, see note. + +Note: The degree of dyskeratosis (some at basal layer), lack of +eosinophils, and finding of lymphocyte-keratinocyte satellitosis +favor graft versus host disease, if clinically appropriate. The +histologic differential diagnosis includes a drug eruption.. +This case was discussed with Dr. [**Last Name (STitle) **] on [**2124-5-30**]. +2. Skin, left upper back, biopsy (C): + +Interface and superficial perivascular dermatitis with marked +dyskeratosis, dermal melanophages, and extravasated +erythrocytes, see note. + +Note: The degree of dyskeratosis (some at basal layer), lack of +eosinophils, and finding of lymphocyte-keratinocyte satellitosis +favor graft versus host disease, if clinically appropriate. The +histologic differential diagnosis includes a drug eruption. +This case was discussed with Dr. [**Last Name (STitle) **] on [**2124-5-30**]. + +[**2124-5-18**] GI BX +DIAGNOSIS: + +Terminal ileum, biopsy: + +Granulation tissue and ulcer bed with crystalline material. See +note. + +Note: No intact intestinal epithelium is seen. The crystalline +material is morphologically consistent with sodium polystyrene +sulfonate (Kayexalate), which is reported to be associated with +gastrointestinal tract ulcers. Reactive atypia is noted within +the granulation tissue, however, no definite viral inclusions +are identified. An immunohistochemical stain for +cytomegalovirus is in process and results will be reported as an +addendum. Severe acute graft versus host disease cannot be +excluded based on the morphologic findings. The case was +reviewed with Dr. [**Last Name (STitle) **] [**Last Name (NamePattern4) 7108**], who concurs. The findings were +discussed with Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] on [**2124-5-19**]. + +ADDENDUM: +Immunohistochemical stain for CMV is negative. + +[**2124-3-30**] - SIGMOIDOSCOPY - Impression: Diverticulosis of the +sigmoid colon +Normal mucosa in the sigmoid colon (biopsy) +Otherwise normal sigmoidoscopy to descending colon at 50 cm +. +[**2124-3-30**] - PATHOLOGY - GI BIOPSIES (2 JARS) +DIAGNOSIS: +Colonic mucosa biopsies, two: +A. Sigmoid: Colonic mucosa, no diagnostic abnormalities +recognized. +B. Rectum: Colonic mucosa with rare crypt cell apoptosis, see +note. +Note: These findings are not diagnostic for GVHD. Immunostain +for CMV is negative. +. +[**2124-4-12**] - PATHOLOGY - Skin, abdomen: +- Interface dermatitis with dyskeratotic keratinocytes, and mild +superficial perivascular lymphocytic infiltrate consistent with +graft versus host disease, see note. +Note: The histological differential diagnosis includes a +reaction to drugs. The current specimen shows +lymphocyte-keratinocyte satellitosis and marked apoptic bodies +at the interface level, and no eosinophilia is noted. The +keratinocytic dyskeratosis is predominantly seen at the basal +keratinocytes level, and no dermal edema is seen. Overall, a +diagnosis of graft versus host disease (GVHD) is favored, if +compatible with the clinical presentation. +. +MICROBIOLOGY TESTS: +[**2124-4-15**] BLOOD CULTURE Blood Culture, Routine-FINAL +{STREPTOCOCCUS ANGINOSUS (MILLERI) GROUP}; Anaerobic Bottle Gram +Stain-FINAL +Anaerobic Bottle Gram Stain-FINAL INPATIENT +FINAL SENSITIVITIES. + CLINDAMYCIN RESISTANT @ > 2MCG/ML. + ERYTHROMYCIN RESISTANT @>4MCG/ML. + Sensitivity testing performed by Sensititre. + SENSITIVITIES: MIC expressed in +MCG/ML +_________________________________________________________ + STREPTOCOCCUS ANGINOSUS (MILLERI) +GROUP + | +CLINDAMYCIN----------- R +ERYTHROMYCIN---------- R +PENICILLIN G---------- 0.06 S +VANCOMYCIN------------ 1 S + + Anaerobic Bottle Gram Stain (Final [**2124-4-16**]): + +[**2124-4-16**] BLOOD CULTURE -FINAL {STREPTOCOCCUS ANGINOSUS +(MILLERI) GROUP} +[**2124-4-18**] BLOOD CULTURE -FINAL NO GROWTH. + +Brief Hospital Course: +Mr. [**Known lastname **] is a 56-year-old male with history of CLL with large +cell transformation who was admitted for a scheduled allogeneic +MUD SCT on [**2124-3-10**]. His course was complicated by febrile +neutropenia and acute GVHD involving the intestinal tract, liver +and skin. He was discharged to [**Hospital1 **] in stable condition +with symptomatic improvement. += += += += += += += += += += += += += += += += += += += += += +================================================================ +[**Date range (3) 60072**] +# Allo BMT - Day 0: [**2124-3-10**] from MUD ([**7-27**], mismatch at one +HLA-A allele). The patient underwent a Busulfan/Cytoxan +conditioning regimen which did not cause neutropenia and he +tolerated it with only mild diarrhea. His initial transplant +proceeded without incident. The patient was started on +Acyclovir, Fluconazole and Ursodiol per protocol on Day -2. +Cyclosporine was started Day -1 and monitored by level. +Methotrexate was given per protocol on Days +1, and then again +on Day +7 (delayed due to concern of transaminitis - see below), +and day +11. He received inhaled pentamidine on a monthly basis +([**3-29**] and [**4-30**]). He was started on atovaquone for PCP +prophylaxis on [**4-8**]. Fungal prophylaxis was switched micafungin +while the patient had fever & neutropenia. The patient was on +voriconazole for a short period of time, but changed back to +micafungin due to concern of exacerbating chemotherapy induced +liver toxicity. +. +# Acute GVHD - The patient course was complicated by acute GVHD +which started as a blanching rash on [**3-20**]. The patient was +treated empirically for GVHD with steroids, which improved his +rash, but when the steroids were tapered the patient developed +severe watery diarrhea, up to 2L a day at times. The +gastroenterology service was consulted and on [**3-30**] the patient +had a flexible sigmoidoscopy. Biopsies of the sigmoid and rectum +were non-diagnostic but consistent with GVHD. Stool cultures +for bacterial and viral pathogens and for C. diff were negative. + The steroids were again tapered as the patient's diarrhea +improved, however, the patient developed a morbilliform rash and +his diarrhea worsened. Dermatology biopsied the rash, and the +pathology was consistent with GVHD. His skin rash evolved into +desquamation and bullae and his diarrhea symptoms flared when +steroids doses were tapered. The patient was treated with +high-dose (2mg/kg) methylprednisone, cellcept, cyclosporine and +Remicade x 2 ([**4-14**] and [**4-22**]). He also developed liver +involvement with GVHD. His TBili was elevated to max of 2.7 on +[**4-24**]. After his second dose of remicade, his symptoms improved +and a very slow steroid taper was reattempted. Steroid taper +was ultimately unsuccessful with patient requiring +methylprednisolone 25 mg in am and 20 mg in pm. + +It was thought that the skin rash may have been worsened by +cefepime. The cefepime was switched to meropenem and derm was +once again consulted on [**5-31**]. Derm took a biopsy which showed +results consistent with GVHD and unlikely for drug reaction. +. +# Fevers and neutropenia - The patient developed fevers in the +setting of neutropenia post transplant on [**3-13**] and was treated +with broad spectrum antibiotics and antifungal coverage. +Cultures remained negative and no source was identified. C diff +was negative on multiple occasions throughout this +hospitalization. His counts recovered ([**3-22**]) and antibiotics were +discontinued. +. +# VRE bacteremia - The patient developed bloody diarrhea and +underwent colonoscopy for evaluation ([**5-18**]). He was +hemodynamically stable at this time. The colonscopy was negative +as was an EGD. The following evening the patient developed a +fever to 102 and blood cultures grew VRE bacteremia. He was +started on linezolid and cefepime. His IJ was removed as was his +PICC line for access. The fevers resolved as did the bacteremia. +. +# Fevers - The patient again became febrile on [**5-31**]. He had no +symptoms and his vital signs remained stable. The patient was +continued on meropenem, linezolid and flagyl was added to cover +potential c. diff. He consistently cultured negative. His PICC +was removed with no resolution of the fevers. His IJ was removed +on [**6-9**]. Following this his fevers resolved. +. +# HHV6 infection: The patient spiked a fever [**3-27**] when he was +no longer neutropenic and he developed a splotchy and evanescent +rash, which disappeared within 24 hours. A serum HHV6 viral +load was eventually positive, and HHV6 was felt to be the likely +cause of the patient??????s rash. Repeat testing a week later for +HHV6 was negative. +. +# Strept Milleri Bacteremia: On [**4-15**] blood cultures were drawn +as the patient appeared unwell and had borderline low blood +pressures. The patient was not neutropenic at this time. Blood +cultures eventually grew Strep milleri. The patient was treated +with vancomycin initially and then switched to ceftazadime and +flagyl and then to cefepime per ID recommendations. TTE was +negative for endocarditis. The patient was deemed to high risk +to undergo TEE so it was determined that he would complete a 4 +week course from the first negative blood culture on [**4-18**] (D/C ON +[**5-15**]). +. +# BK virus: In early [**Month (only) **], while the patient was on multiple +immunosuppressant medications for GVHD, he developed dysuria, +difficulty voiding and hematuria. There was initially concern +about urinary retention; however, once the foley was placed the +patient only had a small amount drained from the bladder. Urine +bacterial cultures were negative, but urine studies were +positive for BK virus. He eventually developed BK viremia. The +patient suffered from painful bladder spasms as a result of his +BK virus. Urology service was consulted to assist with bladder +spasm control. His bladder spasms were symptomatically managed +with flomax, detrol, pyridium and a morphine PCA. ID was +consulted and they recommended treatment with intravesicular +cedofivir. In addition, the patient was given IVIG on [**5-6**] to +help boost his Ig levels in the setting of such high levels of +immunosuppression. Urology recommended an outpatient cystoscopy +after discharge for further evaluation of microscopic hematuria. +. +# Decreased Mental Status - In Mid [**2124-5-17**], patient had +waxing/[**Doctor Last Name 688**] mental status: AOx2, missing date, with a mild +decrease in his mental status. On [**6-13**] the patient's mental +status worsened. He was able to follow simple commands but not +complex commands. He was also complaining of some visual +halluciantions and made some coherent but nonsensical +statements. An MRI was conducted which showed no pathology that +would account for the mental status change. Neurology was +consulted. It was thought that the most likely cause was +metabolic encephalopathy secondary to one of his medications. In +the past he has had similar symptoms in response to cyclosporin. +At that time he was given a cyclosporin holiday and changed to +tacrolimus with a recovery of his mental status to baseline. He +is also on steroids and mycophenolate and received etanercept. + +#) Hypertension: The patient has a history hypertension that is +generally exacerbated by steroids. His anti-hypertensive +medications required frequent adjustment during this +hospitalization. His Diltiazem was changed to Nifedipine due to +concern regarding hepatotoxicity. His metoprolol dose was +increased. On [**6-11**] nifedipine was stopped due to low blood +pressures. +. +#) Anascarca: The patient's severe GVHD caused an inflammatory +state with required aggressive fluid replacement. The patient +developed severe anascarca and ascites and had an approximately +40lb weight gain secondary to GVHD. Once his GVHD stabilized, +he was diuresed with lasix which at one point caused prerenal +acute renal failure with a creatinine peak of 1.7. However, +this resolved with fluids. Patient currently has 1+ edema +bilaterally in both legs, but no other symptoms of fluid +overlaod. +. +#) Superficial venous clots: On [**4-14**], the patient developed +superficial venous clots in his left cephalic and basilic veins +near a PICC line site. He did not have any DVT. +. +#) GERD: The patient was started on a PPI on [**3-28**] due to +increased symptoms of ""heartburn"" in the setting of high dose +steroids. He was discharged with omeprazole 20mg. +. +#) Access: The patient had multiple central lines at various +times during this hospitalization, which were required as the +patient was unable to take POs. He had a Hickmann tunnelled +catheter which was removed because it was non-functional. He +also had right PICC x2 (the first of which was removed due to a +superficial phlebitis), a left IJ, a right subclavian (removed +when the patient was bacteremic) and a right IJ. He currently +has no central access. + += += += += += += += += += += += += += += += += += += += +================================================================ +[**Hospital Unit Name 153**] (Intensive Care Unit) course ([**Date range (2) 60073**]) +. +# Hypothermia / MS changes: Multiple possible etiologies in the +immunocompromised pt s/p BMT, concern for sepsis given elevated +lactate (although unclear as to what pt's baseline lactate level +is given malignancy and adenopathy, was stable at 3.0 on +transfer) and resp alkalosis. Pt had recent VRE bacteremia, +after central line placement, the midline was removed and sent +for culture. MRI shows possible embolic infarcts which raises +concern for endocarditis as another possible source of sepsis. +TSH was low normal ruling out hypothyroid myxedema. Concern for +meningitis or other central process given persistent resp +alkalosis. Additional concern for med toxicity given hx of MS +changes with cyclosporine. LP was performed and suggestive of +possible aseptic meningitis, etiologies include HSV and other +viruses (CMV, HHV, number of others sent out) vs malignancy +related as 99% lymphs on tap vs drug (chemo/immunosup) toxicity. +Ammonia level normal. BMT/heme thought that the CSF lymphs were +not likely malignant. ID recommended coverage for empiric HSV +with foscarnet (due to better coverage of HSV 6). ID also +recommended, f/u galactomannan, B-D-glucan as another survey for +invasive fungal infection without need for broader fungal +coverage now. We initially placed the patient on Linezolid, +cipro, Meropenem, flagyl, Micafungin, foscarnet and Atovaquone +(pt not taking since NPO), but then d/c'd cipro once it was felt +that pseudomonas was unlikely. The pt reported having some loose +stools but C. diff was negative and empiric flagyl treatment was +d/c'd. Atovaquone was restarted when pt able to PO clear liquid +diet. Otherwise, with this treatment the patient became +normothermic with temps >96, with improved mental status, and +hemodynamically stable (never with need for +intubation/pressors). +. +# Anemia: HCT 22 from 26, now stable 23. Not likely dilutional +(Plts, WBC increased). [**Month (only) 116**] be related to blood draws vs +bleeding. 2U pRBC given. Hemolysis/DIC labs negative. Continue +to monitor daily labs. +. +Upon discharge from [**Hospital Unit Name 153**]: [**2124-6-20**]: +#GVHD - The patient continued to have copious diarrhea since his +discharge from the [**Hospital Unit Name 153**]. The patient was restarted on +etanercept on [**6-28**]. This was held for several days when the +patient appeared septic on [**7-12**], however, was restarted on +[**2124-7-15**] after the patient's condition improved, and then finally +d/c'd again the week after. The diarrhea improved significantly +on tincture of opium, however this caused the patient to become +confused. He was switched to lomotil which has alleviated the +diarrhea somewhat. He continues to be on cellcept 1500mg [**Hospital1 **], +budesonide 3mg tid, and methylprednisolone. +. +#MS changes - The patient had multiple episodes of hypothermia +to as low as [**Age over 90 **]F, with associated mental status changes. During +his most recent episode on [**2124-7-12**], his blood pressure also +dropped to 90/60, and he was started on meropenem and daptomycin +because of the possibility of sepsis. The patient's blood +pressure improved with boluses and antibiotics. MRI head was +negative, and LP glucose, protein were normal. However, it was +thought that the daptomycin was potentially causing a further +elevation in his bilirubin, and this was stopped on [**7-15**]. +. +#Adenovirus - The patient was found to have >100,000 copies of +adenovrius in his blod on [**6-28**]. CSF was sent from [**6-26**] which +also showed evidence of adenovirus. However, repeat level on +[**7-6**] showed decreasing adenovirus levels and cidofivir was not +started. A repeat LP was performed on [**2124-7-14**], HHV-6, CMV, +Enterovirus, viral culture, HSV PCR, EBV PCR, [**Male First Name (un) 2326**], Adenovirus +pending. Blood adenovirus level also re-sent. +. +#RUE clot - The patient was found to have a RUE clot [**12-20**] picc +line, however his last U/S showed some resolution. He was not +on anticoag due to hx of GI bleeds, following clinically. +. +#GI bleed - Since leaving the unit, the patient has had several +GI bleeds, first on [**6-29**] after supratherapeutic PTT, more +recently on [**7-11**]. Both episodes were managed conservatively +with fluids given that the likely etiology was graft vs. host +disease. +. +#Ascites/edema - The patient was placed on lasix 20bid to +improve his overall anasarca and ascites. + += += += += += += += += += += += += += += += += += += += += += +================================================================ +From [**2124-7-17**] to [**2124-8-17**] (Date of Discharge) +1. GVHD: By the beginning of [**Month (only) **], the pt did not have any +GVHD associated rash and he was not having any significant +amount of diarrhea, however he did have increases in his LFT's +and total bilirubin (as below) that were associated with altered +mental status, increased somnolence and decreased responsiveness +(see below, AMS). GVHD was in the differential of this liver +dysfunction. He continued on immunosuppressive regimen of +cellcept, Budesonide, Methylprednisolone and enterecept. +Enterecept was eventually discontinued and doses of other +immunosuppressive were readjusted in accordance with liver +function. He was also started on Rituxan once per week and had +received [**1-19**] doses by the time of discharge. By d/c his LFT's +were still increased, with a Tbili holding steady in the 6's. +The amt of diarrhea changed from day to day but was typically +[**12-22**] loose stools per day, occasionally with frank blood, and +occasionally with guiac + but not frankly bloody. On discharge, +patient was kept on Methylprednisone 25mg AM/20mg PM, Cellcept +750mg every 8 hours and budesonide 3mg TID. He will receive one +more dose of Rituxan on [**8-19**]. +. +2. Increased Tbili: This was thought to be GVHD vs drug effect. +The Tbili steadily increased in late [**Month (only) 216**] until early +[**Month (only) **], when it peaked at 9.6 and this was concurrent with +his altered mental staus (as below). Acyclovir was d/c'd. Pt was +to get an MRI abdomen but was unable to sit still long enough to +get it, therefore was sent for CT abdomen with and without +contrast [**2124-7-18**], which showed an interval increase in his +ascites, increase in his pleural effusions L>R, and chronic +ileal wall thickening c/w GVHD. Hepatology was consulted and a +paracentesis was performed in early [**Month (only) **] that was +essentially non-diagnostic, ascites cultures were negative, and +the picture was essentially consistent with portal hypertension. +Rifaxamin was started. Liver Bx was recommended but was not +performed because by this time the pt was clinically improving, +waking up, and AMS was resolving. However, despite the improved +mental status, his LFT's and Tbili continued to increase and +peaked at 9.6 before they again began to decline again and were +steadily in the 6's on d/c. He began to clinically improve, his +scleral icterus got better and no liver Bx was ever performed. +Rifaxamin was stopped without consequence. Acyclovir was added +on and continued at discharge. +. +3. Altered Mental Status: The first week of [**Month (only) **], the +patient was noted to be very somnolent, confused and saying +nonsensical things. Concurrent with this was hypothermia and +hypotension. This was thought to be mostly due to hepatic +encephalopathy. An LP performed on [**7-14**] was non diagnostic and +all viral studies from that procedure were negative. MRI head +[**7-14**] was also non diagnostic. Neuro was consulted and +recommended a 24hr bedside EEG to evaluate for subclinical +seizures, however he eventually began to dramatically turn +around though and became more awake, was conversational, able to +express himself, was requesting food, and EEG was not felt to be +necessary. His mental status steadily cleared up although it was +noted that he would have occasional delirium, would be a little +restless at night (he had actually pulled out a central venous +line one night, another was placed, but he then pulled that one +out several days later), saying odd things in the morning before +he fully woke up, and sundowning a little at night. At baseline, +he is lethargic but appropriate early in the morning, will +follow commands, but later in the day after he has fully woken +up he is very appropriate, concerned about his care, his health +and his plan. +. +4. Hypothermia and Hypotension--Seen to be occasionally +hypotensive to the 90's, which responded to fluid boluses, and +hypothermic to a low of 93.8. Was put on a warmer. The pt's +Metoprolol was d/c'd and his bp's began to improve from high +90's/low 100's to the 110's. Temperature began to improve as +well. By the time the pt's mental status improved, his blood +pressures and hypothermia were no longer an issue. His vital +signs remained stable and hypothermia/hypoTN were not an issue +for several weeks leading up to discharge. In fact, the pt's +blood pressure and heart rate began to increase the week after +Metoprolol was d/c'd and was added back in with a decrease in bp +and pulse seen. He was d/c'd on Metoprolol 12.5 TID with steady +vitals. +. +5. GIB--While he was AMS, pt was not having active GI bleed or +diarrhea issues, but after he woke up he began having loose BM's +with obvious dark red blood. For the next several weeks in +[**Month (only) **], the pt would occasionally have dark red stools, which +required occasional PRBC transfusion, but never compromised him +from a hemodynamic standpoint. He also received occasional +platelets --> During [**Month (only) **], the pt required 6U of PRBC's and +5 of platelets. GI was consulted but felt the pt not stable for +colonoscopy as the large ammount of ascites fluid would lead to +infection. They also felt that he had been scoped within the +past several months and no change would be seen since his +clinical condition was not much changed. By the time of +discharge the pt's Hct was stable, he was having occasional +guiac + stools but not felt to be compromised by them. +. +6. Adenoviremia: Patient was found to have >100,000 copies of +adenovrius in his blood on [**6-28**], also with adenovirus in CSF +from [**6-26**]. Repeat level on [**7-6**] showed decreasing adenovirus +levels at approx. 3000 and cidofivir was not started. A repeat +LP was performed on [**2124-7-14**], HHV-6, CMV, Enterovirus, viral +culture, HSV PCR, EBV PCR, [**Male First Name (un) 2326**], Adenovirus were all negative. +Blood adenovirus level was present and found to be positive at +titer approx. 1900. A repeat measurement later in [**Month (only) **] +showed a titer of 696, and no specific therapy was started. +. +7. RUE clot: Found to have RUE clot of several months duration +but not anti-coagulated due to h/o GIB's. On [**2124-7-24**] pt's R hand +and forearm seen to be acutely grossly swollen, L hand normal, +however by the afternoon the pt's R arm returned to its normal +size without any interventions. It was questioned whether he was +sleeping on that arm which led to its swelling. In any event, +the patient was unable to be anticoagulated to the GIB's. +. +8. Anasarca: The pt was grossly edematous up to his abdomen. +After Metoprolol was d/c'd and hypotension resolved, Lasix was +increased to 40mg IV bid with appropriate response. He continued +to put out urine and as his anasarca steadily decreased his +Lasix was tapered. By the point of discharge, his legs were +drastically reduced from earlier, with barely any baseline +swelling even being noticeable. His Lasix was stopped. +. +9. Nutrition: The patient was started on TPN while his mental +status was poor and he was not eating, but by the time he began +to wake up he was requesting food. TPN was continued for +several weeks even after he had woken up, and eventually was +totally stopped, as the pt was increasingly taking good PO +solids and liquids. He had also pulled out two central lines by +this point and did not have access for TPN anyways. So he was +given a trial to take PO on his own, which he has done well with +by the time of discharge. +. +10. BK viruria: The pt was noted to have RBC's in his UA during +[**Month (only) **] and thus a BK virus assay was sent, which came back >5 +million copies. No specific therapy was initiated. Follow up +UA's then showed that the RBC's were zero. Given recent +complaints of dysuria, another BK virus was sent and results are +pending. +. +11. Mood: The pt had appropriately depressed moods at various +points and was very desolate that he had been in bed 5 mos, +couldn't move his legs, and didn't feel he was making progress. +Remeron was tried for several nights (to increase his sleep at +night and stimulate his appetite) but was thought to increase +restlessness/confusion at night, then was stopped. He was never +tried on any other stimulant or antidepressant. His mood would +likely get better as his clinical condition, mobility, and +overall status improve, and this was repeatedly explained to +him. +. +12. Disposition: The pt basically needs aggressive +rehabilitation at this point, as he has major proximal LE muscle +wasting and myopathy likely due to long term steroid use. He has +good distal LE strength, but cannot stand or lift his legs very +well. If steroids can be tapered, he may be able to regain his +strength. We were attempting to use Rituxan in an attempt to +wean steroids. He is eating and drinking well and needs to be +encouraged to eat and drink. If food and drink is put in front +of him he will eat it. + +Medications on Admission: +Acyclovir 400 mg PO Q8H +Allopurinol 300 mg Tablet PO DAILY +Augmentin 500mg PO TID +Atenolol 100 mg PO Daily +Fluconazole 200 mg PO Q24H +Diltiazem HCl 240 mg PO DAILY +Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H +Pentamidine 300mg inh qm x 6m (last dose [**2124-2-10**]) +Compazine 10mg PO q6-8 PRN nausea +Ativan 0.5-1mg PO q4-6 PRN nausea, anxiety, insomnia + +Discharge Medications: +1. Nystatin 100,000 unit/mL Suspension Sig: Ten (10) ML PO QID +(4 times a day). +2. Saliva Substitution Combo No.2 Solution Sig: One (1) ML +Mucous membrane QID (4 times a day). +3. Oral Wound Care Products Gel in Packet Sig: One (1) ML +Mucous membrane QID (4 times a day) as needed for mouth pain. +4. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +QID (4 times a day) as needed for itching. +5. White Petrolatum-Mineral Oil Cream Sig: One (1) Appl +Topical QID (4 times a day) as needed for GVHD. +6. Atovaquone 750 mg/5 mL Suspension Sig: One (1) PO DAILY +(Daily). +7. Insulin Regular Human 100 unit/mL Solution Sig: One (1) +Injection ASDIR (AS DIRECTED): Please see attached sliding +scale. +8. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed for wheeze. +9. Ursodiol 300 mg Capsule Sig: One (1) Capsule PO BID (2 times +a day). +10. Ergocalciferol (Vitamin D2) 50,000 unit Capsule Sig: One (1) +Capsule PO QSUN ([**Doctor First Name **]). +11. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO ASDIR (AS +DIRECTED). +12. Diphenhydramine HCl 25 mg Capsule Sig: One (1) Capsule PO +ASDIR (AS DIRECTED). +13. Metoprolol Tartrate 25 mg Tablet Sig: 0.5 Tablet PO TID (3 +times a day). +14. Acyclovir 200 mg Capsule Sig: Two (2) Capsule PO BID (2 +times a day). +15. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO BID (2 times a day). +16. Budesonide 3 mg Capsule, Sust. Release 24 hr Sig: One (1) +Capsule, Sust. Release 24 hr PO TID (3 times a day). +17. Mycophenolate Mofetil 500 mg Tablet Sig: 1.5 Tablets PO Q 8H +(Every 8 Hours). +18. Potassium & Sodium Phosphates 280-160-250 mg Powder in +Packet Sig: One (1) Powder in Packet PO ONCE (Once) for 1 doses. + +19. Micafungin 100 mg Recon Soln Sig: One (1) Recon Soln +Intravenous DAILY (Daily). +20. Rituximab 10 mg/mL Concentrate Sig: Seven Hundred-Fifteen +(715) MG Intravenous Give dose #4 (last dose) on [**2124-8-19**] for 1 +doses: Please give 715mg on [**2124-8-19**]. +21. Methylprednisolone Sodium Succ 40 mg/mL Recon Soln Sig: +Twenty Five (25) MG Injection QAM : Please give 25mg of +methylprednisolone sodium succ every morning. +22. Methylprednisolone Sodium Succ 40 mg/mL Recon Soln Sig: +Twenty (20) MG Injection Q PM: Please give 20MG of +methylprednisolone sodium succ every night. + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +Primary/active diagnoses on discharge: +1. CLL s/p [**Doctor Last Name 6261**] Transformation +2. Allogeneic Stem Cell Transplant [**2124-3-10**] +3. Chronic Graft versus Host disease of the liver, GI system, +and skin +4. Chronic GI bleed +5. Chronic Anemia +6. Thrombocytopenia +7. Hypertension +8. BK viruria +9. Adenoviremia +10. Extensive RUE deep venous thromboses + +Discharge Condition: +By the time of discharge, the pt's chronic graft versus host +disease was stable, his chronic GI bleed was not hemodynamically +compromising, the pt had been working with PT to increase his +strength and mobility, was taking good PO foods and liquids, +vital signs were stable, and was medically cleared for +discharge. + +Discharge Instructions: +You have been admitted to the hospital for an allogeneic stem +cell transplant on [**2124-3-10**]. Please see discharge summary for +COMPLETE SUMMARY of your hospital course since [**2124-3-1**]. +. +Please see attached for COMPLETE LIST of your current +medications. This was RECONCILED with admission list. +. +If you experience fever >100, shortness of breath, chest pain, +abdominal pain, headache, pain with urination, weight loss, or +any other concerning symptom, please call Dr. [**Last Name (STitle) **] or 911 +immediately. + +Followup Instructions: +Patient will need complete CBC with differential and complete +chemistry (Chem 10) within 24-48 hours of discharge on [**8-18**]. +Please fax results to Dr. [**Last Name (STitle) **] at: [**Telephone/Fax (1) 21962**]. +. +DR. [**Last Name (STitle) **] AND [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **]: [**2124-8-21**] at 12:30pm. [**Telephone/Fax (1) 3241**] or +[**Telephone/Fax (1) 3237**]. +. +Dr. [**Last Name (STitle) **], MD Phone:[**Telephone/Fax (1) 3241**] Date/Time:[**2124-9-18**] 10:30 +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 9574**], [**MD Number(3) 1240**]:[**Telephone/Fax (1) 3241**] +Date/Time:[**2124-9-18**] 10:30 +. +Urology for blood in urine: Wednesday [**9-20**] at 4pm [**Hospital Ward Name 23**] [**Location (un) **]. + + +",40,2124-03-01 11:10:00,2124-08-17 15:40:00,ELECTIVE,PHYS REFERRAL/NORMAL DELI,LONG TERM CARE HOSPITAL,CHRONIC LYMPHOCYTIC LEUKEMIA\BONE MARROW TRANSPLANT," +mr. [**known lastname **] is a 56-year-old male with history of cll with large +cell transformation who was admitted for a scheduled allogeneic +mud sct on [**2124-3-10**]. his course was complicated by febrile +neutropenia and acute gvhd involving the intestinal tract, liver +and skin. he was discharged to [**hospital1 **] in stable condition +with symptomatic improvement. += += += += += += += += += += += += += += += += += += += += += +================================================================ +[**date range (3) 60072**] +# allo bmt - day 0: [**2124-3-10**] from mud ([**7-27**], mismatch at one +hla-a allele). the patient underwent a busulfan/cytoxan +conditioning regimen which did not cause neutropenia and he +tolerated it with only mild diarrhea. his initial transplant +proceeded without incident. the patient was started on +acyclovir, fluconazole and ursodiol per protocol on day -2. +cyclosporine was started day -1 and monitored by level. +methotrexate was given per protocol on days +1, and then again +on day +7 (delayed due to concern of transaminitis - see below), +and day +11. he received inhaled pentamidine on a monthly basis +([**3-29**] and [**4-30**]). he was started on atovaquone for pcp +prophylaxis on [**4-8**]. fungal prophylaxis was switched micafungin +while the patient had fever & neutropenia. the patient was on +voriconazole for a short period of time, but changed back to +micafungin due to concern of exacerbating chemotherapy induced +liver toxicity. +. +# acute gvhd - the patient course was complicated by acute gvhd +which started as a blanching rash on [**3-20**]. the patient was +treated empirically for gvhd with steroids, which improved his +rash, but when the steroids were tapered the patient developed +severe watery diarrhea, up to 2l a day at times. the +gastroenterology service was consulted and on [**3-30**] the patient +had a flexible sigmoidoscopy. biopsies of the sigmoid and rectum +were non-diagnostic but consistent with gvhd. stool cultures +for bacterial and viral pathogens and for c. diff were negative. + the steroids were again tapered as the patients diarrhea +improved, however, the patient developed a morbilliform rash and +his diarrhea worsened. dermatology biopsied the rash, and the +pathology was consistent with gvhd. his skin rash evolved into +desquamation and bullae and his diarrhea symptoms flared when +steroids doses were tapered. the patient was treated with +high-dose (2mg/kg) methylprednisone, cellcept, cyclosporine and +remicade x 2 ([**4-14**] and [**4-22**]). he also developed liver +involvement with gvhd. his tbili was elevated to max of 2.7 on +[**4-24**]. after his second dose of remicade, his symptoms improved +and a very slow steroid taper was reattempted. steroid taper +was ultimately unsuccessful with patient requiring +methylprednisolone 25 mg in am and 20 mg in pm. + +it was thought that the skin rash may have been worsened by +cefepime. the cefepime was switched to meropenem and derm was +once again consulted on [**5-31**]. derm took a biopsy which showed +results consistent with gvhd and unlikely for drug reaction. +. +# fevers and neutropenia - the patient developed fevers in the +setting of neutropenia post transplant on [**3-13**] and was treated +with broad spectrum antibiotics and antifungal coverage. +cultures remained negative and no source was identified. c diff +was negative on multiple occasions throughout this +hospitalization. his counts recovered ([**3-22**]) and antibiotics were +discontinued. +. +# vre bacteremia - the patient developed bloody diarrhea and +underwent colonoscopy for evaluation ([**5-18**]). he was +hemodynamically stable at this time. the colonscopy was negative +as was an egd. the following evening the patient developed a +fever to 102 and blood cultures grew vre bacteremia. he was +started on linezolid and cefepime. his ij was removed as was his +picc line for access. the fevers resolved as did the bacteremia. +. +# fevers - the patient again became febrile on [**5-31**]. he had no +symptoms and his vital signs remained stable. the patient was +continued on meropenem, linezolid and flagyl was added to cover +potential c. diff. he consistently cultured negative. his picc +was removed with no resolution of the fevers. his ij was removed +on [**6-9**]. following this his fevers resolved. +. +# hhv6 infection: the patient spiked a fever [**3-27**] when he was +no longer neutropenic and he developed a splotchy and evanescent +rash, which disappeared within 24 hours. a serum hhv6 viral +load was eventually positive, and hhv6 was felt to be the likely +cause of the patient??????s rash. repeat testing a week later for +hhv6 was negative. +. +# strept milleri bacteremia: on [**4-15**] blood cultures were drawn +as the patient appeared unwell and had borderline low blood +pressures. the patient was not neutropenic at this time. blood +cultures eventually grew strep milleri. the patient was treated +with vancomycin initially and then switched to ceftazadime and +flagyl and then to cefepime per id recommendations. tte was +negative for endocarditis. the patient was deemed to high risk +to undergo tee so it was determined that he would complete a 4 +week course from the first negative blood culture on [**4-18**] (d/c on +[**5-15**]). +. +# bk virus: in early [**month (only) **], while the patient was on multiple +immunosuppressant medications for gvhd, he developed dysuria, +difficulty voiding and hematuria. there was initially concern +about urinary retention; however, once the foley was placed the +patient only had a small amount drained from the bladder. urine +bacterial cultures were negative, but urine studies were +positive for bk virus. he eventually developed bk viremia. the +patient suffered from painful bladder spasms as a result of his +bk virus. urology service was consulted to assist with bladder +spasm control. his bladder spasms were symptomatically managed +with flomax, detrol, pyridium and a morphine pca. id was +consulted and they recommended treatment with intravesicular +cedofivir. in addition, the patient was given ivig on [**5-6**] to +help boost his ig levels in the setting of such high levels of +immunosuppression. urology recommended an outpatient cystoscopy +after discharge for further evaluation of microscopic hematuria. +. +# decreased mental status - in mid [**2124-5-17**], patient had +waxing/[**doctor last name 688**] mental status: aox2, missing date, with a mild +decrease in his mental status. on [**6-13**] the patients mental +status worsened. he was able to follow simple commands but not +complex commands. he was also complaining of some visual +halluciantions and made some coherent but nonsensical +statements. an mri was conducted which showed no pathology that +would account for the mental status change. neurology was +consulted. it was thought that the most likely cause was +metabolic encephalopathy secondary to one of his medications. in +the past he has had similar symptoms in response to cyclosporin. +at that time he was given a cyclosporin holiday and changed to +tacrolimus with a recovery of his mental status to baseline. he +is also on steroids and mycophenolate and received etanercept. + +#) hypertension: the patient has a history hypertension that is +generally exacerbated by steroids. his anti-hypertensive +medications required frequent adjustment during this +hospitalization. his diltiazem was changed to nifedipine due to +concern regarding hepatotoxicity. his metoprolol dose was +increased. on [**6-11**] nifedipine was stopped due to low blood +pressures. +. +#) anascarca: the patients severe gvhd caused an inflammatory +state with required aggressive fluid replacement. the patient +developed severe anascarca and ascites and had an approximately +40lb weight gain secondary to gvhd. once his gvhd stabilized, +he was diuresed with lasix which at one point caused prerenal +acute renal failure with a creatinine peak of 1.7. however, +this resolved with fluids. patient currently has 1+ edema +bilaterally in both legs, but no other symptoms of fluid +overlaod. +. +#) superficial venous clots: on [**4-14**], the patient developed +superficial venous clots in his left cephalic and basilic veins +near a picc line site. he did not have any dvt. +. +#) gerd: the patient was started on a ppi on [**3-28**] due to +increased symptoms of ""heartburn"" in the setting of high dose +steroids. he was discharged with omeprazole 20mg. +. +#) access: the patient had multiple central lines at various +times during this hospitalization, which were required as the +patient was unable to take pos. he had a hickmann tunnelled +catheter which was removed because it was non-functional. he +also had right picc x2 (the first of which was removed due to a +superficial phlebitis), a left ij, a right subclavian (removed +when the patient was bacteremic) and a right ij. he currently +has no central access. + += += += += += += += += += += += += += += += += += += += +================================================================ +[**hospital unit name 153**] (intensive care unit) course ([**date range (2) 60073**]) +. +# hypothermia / ms changes: multiple possible etiologies in the +immunocompromised pt s/p bmt, concern for sepsis given elevated +lactate (although unclear as to what pts baseline lactate level +is given malignancy and adenopathy, was stable at 3.0 on +transfer) and resp alkalosis. pt had recent vre bacteremia, +after central line placement, the midline was removed and sent +for culture. mri shows possible embolic infarcts which raises +concern for endocarditis as another possible source of sepsis. +tsh was low normal ruling out hypothyroid myxedema. concern for +meningitis or other central process given persistent resp +alkalosis. additional concern for med toxicity given hx of ms +changes with cyclosporine. lp was performed and suggestive of +possible aseptic meningitis, etiologies include hsv and other +viruses (cmv, hhv, number of others sent out) vs malignancy +related as 99% lymphs on tap vs drug (chemo/immunosup) toxicity. +ammonia level normal. bmt/heme thought that the csf lymphs were +not likely malignant. id recommended coverage for empiric hsv +with foscarnet (due to better coverage of hsv 6). id also +recommended, f/u galactomannan, b-d-glucan as another survey for +invasive fungal infection without need for broader fungal +coverage now. we initially placed the patient on linezolid, +cipro, meropenem, flagyl, micafungin, foscarnet and atovaquone +(pt not taking since npo), but then d/cd cipro once it was felt +that pseudomonas was unlikely. the pt reported having some loose +stools but c. diff was negative and empiric flagyl treatment was +d/cd. atovaquone was restarted when pt able to po clear liquid +diet. otherwise, with this treatment the patient became +normothermic with temps >96, with improved mental status, and +hemodynamically stable (never with need for +intubation/pressors). +. +# anemia: hct 22 from 26, now stable 23. not likely dilutional +(plts, wbc increased). [**month (only) 116**] be related to blood draws vs +bleeding. 2u prbc given. hemolysis/dic labs negative. continue +to monitor daily labs. +. +upon discharge from [**hospital unit name 153**]: [**2124-6-20**]: +#gvhd - the patient continued to have copious diarrhea since his +discharge from the [**hospital unit name 153**]. the patient was restarted on +etanercept on [**6-28**]. this was held for several days when the +patient appeared septic on [**7-12**], however, was restarted on +[**2124-7-15**] after the patients condition improved, and then finally +d/cd again the week after. the diarrhea improved significantly +on tincture of opium, however this caused the patient to become +confused. he was switched to lomotil which has alleviated the +diarrhea somewhat. he continues to be on cellcept 1500mg [**hospital1 **], +budesonide 3mg tid, and methylprednisolone. +. +#ms changes - the patient had multiple episodes of hypothermia +to as low as [**age over 90 **]f, with associated mental status changes. during +his most recent episode on [**2124-7-12**], his blood pressure also +dropped to 90/60, and he was started on meropenem and daptomycin +because of the possibility of sepsis. the patients blood +pressure improved with boluses and antibiotics. mri head was +negative, and lp glucose, protein were normal. however, it was +thought that the daptomycin was potentially causing a further +elevation in his bilirubin, and this was stopped on [**7-15**]. +. +#adenovirus - the patient was found to have >100,000 copies of +adenovrius in his blod on [**6-28**]. csf was sent from [**6-26**] which +also showed evidence of adenovirus. however, repeat level on +[**7-6**] showed decreasing adenovirus levels and cidofivir was not +started. a repeat lp was performed on [**2124-7-14**], hhv-6, cmv, +enterovirus, viral culture, hsv pcr, ebv pcr, [**male first name (un) 2326**], adenovirus +pending. blood adenovirus level also re-sent. +. +#rue clot - the patient was found to have a rue clot [**12-20**] picc +line, however his last u/s showed some resolution. he was not +on anticoag due to hx of gi bleeds, following clinically. +. +#gi bleed - since leaving the unit, the patient has had several +gi bleeds, first on [**6-29**] after supratherapeutic ptt, more +recently on [**7-11**]. both episodes were managed conservatively +with fluids given that the likely etiology was graft vs. host +disease. +. +#ascites/edema - the patient was placed on lasix 20bid to +improve his overall anasarca and ascites. + += += += += += += += += += += += += += += += += += += += += += +================================================================ +from [**2124-7-17**] to [**2124-8-17**] (date of discharge) +1. gvhd: by the beginning of [**month (only) **], the pt did not have any +gvhd associated rash and he was not having any significant +amount of diarrhea, however he did have increases in his lfts +and total bilirubin (as below) that were associated with altered +mental status, increased somnolence and decreased responsiveness +(see below, ams). gvhd was in the differential of this liver +dysfunction. he continued on immunosuppressive regimen of +cellcept, budesonide, methylprednisolone and enterecept. +enterecept was eventually discontinued and doses of other +immunosuppressive were readjusted in accordance with liver +function. he was also started on rituxan once per week and had +received [**1-19**] doses by the time of discharge. by d/c his lfts +were still increased, with a tbili holding steady in the 6s. +the amt of diarrhea changed from day to day but was typically +[**12-22**] loose stools per day, occasionally with frank blood, and +occasionally with guiac + but not frankly bloody. on discharge, +patient was kept on methylprednisone 25mg am/20mg pm, cellcept +750mg every 8 hours and budesonide 3mg tid. he will receive one +more dose of rituxan on [**8-19**]. +. +2. increased tbili: this was thought to be gvhd vs drug effect. +the tbili steadily increased in late [**month (only) 216**] until early +[**month (only) **], when it peaked at 9.6 and this was concurrent with +his altered mental staus (as below). acyclovir was d/cd. pt was +to get an mri abdomen but was unable to sit still long enough to +get it, therefore was sent for ct abdomen with and without +contrast [**2124-7-18**], which showed an interval increase in his +ascites, increase in his pleural effusions l>r, and chronic +ileal wall thickening c/w gvhd. hepatology was consulted and a +paracentesis was performed in early [**month (only) **] that was +essentially non-diagnostic, ascites cultures were negative, and +the picture was essentially consistent with portal hypertension. +rifaxamin was started. liver bx was recommended but was not +performed because by this time the pt was clinically improving, +waking up, and ams was resolving. however, despite the improved +mental status, his lfts and tbili continued to increase and +peaked at 9.6 before they again began to decline again and were +steadily in the 6s on d/c. he began to clinically improve, his +scleral icterus got better and no liver bx was ever performed. +rifaxamin was stopped without consequence. acyclovir was added +on and continued at discharge. +. +3. altered mental status: the first week of [**month (only) **], the +patient was noted to be very somnolent, confused and saying +nonsensical things. concurrent with this was hypothermia and +hypotension. this was thought to be mostly due to hepatic +encephalopathy. an lp performed on [**7-14**] was non diagnostic and +all viral studies from that procedure were negative. mri head +[**7-14**] was also non diagnostic. neuro was consulted and +recommended a 24hr bedside eeg to evaluate for subclinical +seizures, however he eventually began to dramatically turn +around though and became more awake, was conversational, able to +express himself, was requesting food, and eeg was not felt to be +necessary. his mental status steadily cleared up although it was +noted that he would have occasional delirium, would be a little +restless at night (he had actually pulled out a central venous +line one night, another was placed, but he then pulled that one +out several days later), saying odd things in the morning before +he fully woke up, and sundowning a little at night. at baseline, +he is lethargic but appropriate early in the morning, will +follow commands, but later in the day after he has fully woken +up he is very appropriate, concerned about his care, his health +and his plan. +. +4. hypothermia and hypotension--seen to be occasionally +hypotensive to the 90s, which responded to fluid boluses, and +hypothermic to a low of 93.8. was put on a warmer. the pts +metoprolol was d/cd and his bps began to improve from high +90s/low 100s to the 110s. temperature began to improve as +well. by the time the pts mental status improved, his blood +pressures and hypothermia were no longer an issue. his vital +signs remained stable and hypothermia/hypotn were not an issue +for several weeks leading up to discharge. in fact, the pts +blood pressure and heart rate began to increase the week after +metoprolol was d/cd and was added back in with a decrease in bp +and pulse seen. he was d/cd on metoprolol 12.5 tid with steady +vitals. +. +5. gib--while he was ams, pt was not having active gi bleed or +diarrhea issues, but after he woke up he began having loose bms +with obvious dark red blood. for the next several weeks in +[**month (only) **], the pt would occasionally have dark red stools, which +required occasional prbc transfusion, but never compromised him +from a hemodynamic standpoint. he also received occasional +platelets --> during [**month (only) **], the pt required 6u of prbcs and +5 of platelets. gi was consulted but felt the pt not stable for +colonoscopy as the large ammount of ascites fluid would lead to +infection. they also felt that he had been scoped within the +past several months and no change would be seen since his +clinical condition was not much changed. by the time of +discharge the pts hct was stable, he was having occasional +guiac + stools but not felt to be compromised by them. +. +6. adenoviremia: patient was found to have >100,000 copies of +adenovrius in his blood on [**6-28**], also with adenovirus in csf +from [**6-26**]. repeat level on [**7-6**] showed decreasing adenovirus +levels at approx. 3000 and cidofivir was not started. a repeat +lp was performed on [**2124-7-14**], hhv-6, cmv, enterovirus, viral +culture, hsv pcr, ebv pcr, [**male first name (un) 2326**], adenovirus were all negative. +blood adenovirus level was present and found to be positive at +titer approx. 1900. a repeat measurement later in [**month (only) **] +showed a titer of 696, and no specific therapy was started. +. +7. rue clot: found to have rue clot of several months duration +but not anti-coagulated due to h/o gibs. on [**2124-7-24**] pts r hand +and forearm seen to be acutely grossly swollen, l hand normal, +however by the afternoon the pts r arm returned to its normal +size without any interventions. it was questioned whether he was +sleeping on that arm which led to its swelling. in any event, +the patient was unable to be anticoagulated to the gibs. +. +8. anasarca: the pt was grossly edematous up to his abdomen. +after metoprolol was d/cd and hypotension resolved, lasix was +increased to 40mg iv bid with appropriate response. he continued +to put out urine and as his anasarca steadily decreased his +lasix was tapered. by the point of discharge, his legs were +drastically reduced from earlier, with barely any baseline +swelling even being noticeable. his lasix was stopped. +. +9. nutrition: the patient was started on tpn while his mental +status was poor and he was not eating, but by the time he began +to wake up he was requesting food. tpn was continued for +several weeks even after he had woken up, and eventually was +totally stopped, as the pt was increasingly taking good po +solids and liquids. he had also pulled out two central lines by +this point and did not have access for tpn anyways. so he was +given a trial to take po on his own, which he has done well with +by the time of discharge. +. +10. bk viruria: the pt was noted to have rbcs in his ua during +[**month (only) **] and thus a bk virus assay was sent, which came back >5 +million copies. no specific therapy was initiated. follow up +uas then showed that the rbcs were zero. given recent +complaints of dysuria, another bk virus was sent and results are +pending. +. +11. mood: the pt had appropriately depressed moods at various +points and was very desolate that he had been in bed 5 mos, +couldnt move his legs, and didnt feel he was making progress. +remeron was tried for several nights (to increase his sleep at +night and stimulate his appetite) but was thought to increase +restlessness/confusion at night, then was stopped. he was never +tried on any other stimulant or antidepressant. his mood would +likely get better as his clinical condition, mobility, and +overall status improve, and this was repeatedly explained to +him. +. +12. disposition: the pt basically needs aggressive +rehabilitation at this point, as he has major proximal le muscle +wasting and myopathy likely due to long term steroid use. he has +good distal le strength, but cannot stand or lift his legs very +well. if steroids can be tapered, he may be able to regain his +strength. we were attempting to use rituxan in an attempt to +wean steroids. he is eating and drinking well and needs to be +encouraged to eat and drink. if food and drink is put in front +of him he will eat it. + + ","PRIMARY: [Other malignant lymphomas, unspecified site, extranodal and solid organ sites] +SECONDARY: [Acute kidney failure, unspecified; Toxic encephalopathy; Other specified septicemias; Sepsis; Hepatic encephalopathy; Chronic lymphoid leukemia, without mention of having achieved remission; Other complications due to other vascular device, implant, and graft; Acute venous embolism and thrombosis of superficial veins of upper extremity; Complications of transplanted bone marrow; Acute graft-versus-host disease; Bacteremia; Unspecified pleural effusion; Other ascites; Urinary tract infection, site not specified; Acute venous embolism and thrombosis of subclavian veins; Alkalosis; Meningitis due to adenovirus; Hemorrhage of gastrointestinal tract, unspecified; Portal hypertension; Hyposmolality and/or hyponatremia; Toxic myopathy; Other disorders of neurohypophysis; Candidiasis of mouth; Other specified erythematous conditions; Diarrhea; Neutropenia, unspecified; Fever presenting with conditions classified elsewhere; Hepatitis, unspecified; Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Streptococcus infection in conditions classified elsewhere and of unspecified site, streptococcus, group D [Enterococcus]; Infection with microorganisms without mention of resistance to multiple drugs; Streptococcus infection in conditions classified elsewhere and of unspecified site, other streptococcus; Human herpesvirus 6 infection; Other specified viral infection; Microscopic hematuria; ; Pure hypercholesterolemia; Unspecified essential hypertension]" +43147,180640.0,12752,2127-03-27,12751,161625.0,2127-03-09,Discharge summary,"Admission Date: [**2127-3-3**] Discharge Date: [**2127-3-9**] + + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 2297**] +Chief Complaint: +Respiratory distress + +Major Surgical or Invasive Procedure: +ICU monitoring, central venous catheter placement, PICC line +placement, arterial catheter placement. + +History of Present Illness: +89f with large pna requiring intbuation. Presented from rehab +facility, found to have change in mental status with severe +respiratory distress, transferred to [**Hospital1 18**]. + + In [**Hospital1 18**] ED, t103 rectally, 182/120, rr30, sats 90% on face +mask, GCS 3. Pt intubated with use of fentanyl versed, CXR +showed R-sided pna ""over entire lung."" Given ceftriaXONE, +vancomycin 1g, acetaminophen rectally 650mg for HAP pneumonia. +Vital signs on transfer 129/70, hr91, 5peep ac fio2 10%, 100% +sats. 2pIVs. + + Of note, recent hospitalized [**2-10**] at [**Hospital1 18**] for R-ACA infarct. +echo unremarkbale, started on asa, statin. Pt had ""pneumonia"" +on admit; On Amp-Sulbactam (Unasyn) 3g IV q6 on [**2127-2-11**], +Follow-up CXR on [**2-12**] looked worse than her initial IV +cipro/flagyl [**2127-2-13**]. Then on [**2-18**] changed to Amp-Clavunalic +500mg q8 and PO cipro/flagyl x5d (finished [**2127-2-24**]). A CXR was +obtained on [**2-18**] which showed stable findings. During her +hospital stay, she was hypertensive thus treated with lisinopril +and metoprolol. Physical exam on discharge from that admission +was remarkable for abulia and decreased strength on left. + + +Past Medical History: +1. Hypertension, recently poorly controlled and fluctuating +2. Alzheimer's dementia +3. Pituitary macroadenoma, followed and unchanged per CT scans +at [**Hospital3 **] (2.5 cm) +4. Autonomic dysfunction, hyponatremia, secondary to ?SIADH +([**2119**])/free water intake +5. Low TSH +6. Thyroid Goiter +7. Syncopal episodes +8. Anemia of chronic disease + + +Social History: +Since the R ACA stroke, pt has been living in a rehab. Fully +dependent, as she is hemiplegic on left and alert and oriented +to first name only. +Per medical records: Tob: denies. EtOH: denies. Drugs: denies + +Family History: +Noncontributory + +Physical Exam: +General: Not responsive to voice. +HEENT: Sclera anicteric, MMM +Neck: supple, JVP not elevated, no LAD +Lungs: scattered rales, rhonchi R>L +CV: RRR, normal S1 + S2, no murmurs, rubs, gallops +Abdomen: soft, non-tender, non-distended, bowel sounds present, +no organomegaly +Ext: Warm, well perfused, 2+ pulses, no clubbing, cyanosis, 1+ +anasarca. + +Pertinent Results: +[**2127-3-3**] 07:25PM BLOOD WBC-12.9* RBC-3.35* Hgb-10.1* Hct-31.6* +MCV-94 MCH-30.2 MCHC-32.0 RDW-15.1 Plt Ct-429 +[**2127-3-8**] 04:50AM BLOOD WBC-16.3* RBC-2.80* Hgb-8.5* Hct-26.1* +MCV-93 MCH-30.2 MCHC-32.4 RDW-15.3 Plt Ct-304 +[**2127-3-8**] 04:50AM BLOOD PT-14.0* PTT-31.9 INR(PT)-1.2* +[**2127-3-3**] 07:25PM BLOOD Glucose-139* UreaN-19 Creat-0.7 Na-138 +K-6.1* Cl-111* HCO3-23 AnGap-10 +[**2127-3-8**] 04:50AM BLOOD Glucose-121* UreaN-22* Creat-0.8 Na-137 +K-3.6 Cl-101 HCO3-26 AnGap-14 +[**2127-3-3**] 07:25PM BLOOD ALT-45* AST-119* LD(LDH)-587* CK(CPK)-69 +AlkPhos-129* TotBili-0.3 +[**2127-3-5**] 03:45AM BLOOD ALT-30 AST-44* LD(LDH)-299* AlkPhos-114 +TotBili-0.3 +[**2127-3-3**] 07:25PM BLOOD CK-MB-NotDone proBNP-[**Numeric Identifier 3602**]* +[**2127-3-3**] 07:25PM BLOOD cTropnT-0.04* +[**2127-3-4**] 02:11AM BLOOD CK-MB-5 cTropnT-0.05* +[**2127-3-4**] 01:30PM BLOOD CK-MB-NotDone cTropnT-0.07* +[**2127-3-3**] 07:25PM BLOOD Albumin-2.0* Calcium-6.1* Phos-2.8 +Mg-1.5* +[**2127-3-8**] 04:50AM BLOOD Calcium-8.3* Phos-3.3 Mg-2.1 +[**2127-3-3**] 07:25PM BLOOD TSH-0.26* +[**2127-3-3**] 07:25PM BLOOD Free T4-1.2 +[**2127-3-3**] 07:25PM BLOOD Cortsol-38.2* +[**2127-3-3**] 08:42PM BLOOD Type-ART Tidal V-500 PEEP-5 FiO2-100 +pO2-202* pCO2-30* pH-7.46* calTCO2-22 Base XS-0 AADO2-481 REQ +O2-81 Intubat-INTUBATED Vent-CONTROLLED +[**2127-3-8**] 08:23AM BLOOD Type-ART Temp-38.3 FiO2-36 O2 Flow-15 +pO2-107* pCO2-49* pH-7.46* calTCO2-36* Base XS-9 Intubat-NOT +INTUBA +[**2127-3-3**] 07:37PM BLOOD Lactate-2.6* +[**2127-3-8**] 08:23AM BLOOD Lactate-1.9 +[**2127-3-4**] 03:16AM BLOOD freeCa-1.08* +[**2127-3-7**] 03:09AM BLOOD freeCa-1.11* +. +Discharge labs: +[**2127-3-9**] 03:28AM BLOOD WBC-18.2* RBC-2.67* Hgb-8.0* Hct-24.6* +MCV-92 MCH-29.4 MCHC-31.9 RDW-14.9 Plt Ct-308 +[**2127-3-9**] 03:28AM BLOOD Neuts-86.2* Lymphs-7.4* Monos-3.5 Eos-2.7 +Baso-0.2 +[**2127-3-9**] 03:28AM BLOOD Glucose-126* UreaN-24* Creat-0.9 Na-136 +K-3.2* Cl-105 HCO3-26 AnGap-8 +[**2127-3-9**] 03:28AM BLOOD Calcium-8.1* Phos-3.1 Mg-1.9 +. +Microbiology: + +[**2127-3-3**] BLOOD CULTURE Blood Culture, Routine-FINAL +{ENTEROCOCCUS FAECIUM, PRESUMPTIVE CLOSTRIDIUM PERFRINGENS}; +Aerobic Bottle Gram Stain-FINAL; Anaerobic Bottle Gram Stain-neg +[**2127-3-3**] BLOOD CULTURE Blood Culture, Routine-Neg +[**2127-3-5**] BLOOD CULTURE Blood Culture, Routine-No growth to +date +[**2127-3-5**] BLOOD CULTURE Blood Culture, Routine-No growth to +date +[**2127-3-9**] BLOOD CULTURE Blood Culture, Routine-No growth to +date + +[**2127-3-4**] STOOL CLOSTRIDIUM DIFFICILE TOXIN A & B TEST-neg +[**2127-3-6**] STOOL CLOSTRIDIUM DIFFICILE TOXIN A & B TEST-neg +[**2127-3-9**] STOOL CLOSTRIDIUM DIFFICILE TOXIN A & B TEST-pending + +[**2127-3-4**] SPUTUM GRAM STAIN-FINAL; RESPIRATORY CULTURE-yeast, +sparse growth +[**2127-3-5**] SPUTUM GRAM STAIN-FINAL; RESPIRATORY CULTURE-yeast, +sparse growth + +[**2127-3-3**] URINE URINE CULTURE-FINAL neg +[**2127-3-5**] URINE URINE CULTURE-FINAL neg + +[**2127-3-4**] Rapid Respiratory Viral Screen & Culture Respiratory +Viral Culture-neg; Rapid Respiratory Viral Antigen Test-neg + +[**2127-3-4**] BRONCHOALVEOLAR LAVAGE GRAM STAIN- 4+ PMNs; +RESPIRATORY CULTURE-no growth; LEGIONELLA CULTURE- neg; VIRAL +CULTURE: R/O CYTOMEGALOVIRUS-no growth to date + +[**2127-3-4**] MRSA SCREEN MRSA SCREEN-FINAL INPATIENT +[**2127-3-3**] URINE Legionella Urinary Antigen -FINAL INPATIENT +. +Radiology +. +CXR [**2127-3-3**]: +IMPRESSION: +1. Interval development of multifocal airspace opacities in the +right lung +concerning for pneumonia. +2. Persistent small to moderate sized bilateral pleural +effusions. +3. Slightly low lying endotracheal tube with tip terminating 2.5 +cm superior to the carina. +4. Probable overinflation of the endotracheal cuff balloon. +. +CT head [**2127-3-5**]: +IMPRESSION: +1. Progressive cystic encephalomalacia and volume loss in the +distribution of the right anterior cerebral artery, consistent +with evolution of prior +infarct. +2. Unchanged sellar region mass, with imaging characteristics +most +suggestive of a pituitary macroadenoma, without hemorrhage. +3. No new acute intracranial process, including no hemorrhage, +edema, mass +effect, or acule large vascular territorial infarction. +. +CXR [**2127-3-8**]: +Increase in right upper lobe and left upper lobe multifocal +opacities, could be aspiration/pneumonia. Bilateral pleural +effusion slightly improved. Retrocardiac opacity persists. +Increase in interstitial edema. +. +CT abdomen/pelvis without contrast [**2127-3-8**] +1. No evidence of infectious source to explain bacteremia. +2. Moderate bilateral pleural effusions, with consolidation vs. +atelectasis at the left lung base. + + +Brief Hospital Course: +89F with shock and respiratory failure likely from pna. +. +# Respiratory Failure: Patient was hypoxic with CXR showing +multifocal right lobe infiltrate. Patient had recent ACA stroke +and failed speach and swallow and not thought to be a good +candidate for tube feeds but the family wanted to continue to +feed her, putting her at high risk for aspiration. She was +intubated on presentation to the hospital and then extubated +successfully on [**2127-3-6**]. +- Pt was started on Vanco/Zosyn for HAP given recent hospital +stay and current living situation in the rehab. Pt received 6 +days of Vancomycin, after which it was discontinued. Zosyn was +continued and pt should complete a course of 14 days (Day +1=[**3-3**]) +- On discharge, pt was satting in high 90s to 100 on FiO2 of +35%. +- sputum gram stain showed less than 25 PMNs and culture grew +rare yeast. +- urine legionella was negative. +- Bronchoalveolar lavage sample showed 4+ PMNs, CMV culture +negative to date, andrespiratory cultures negative. +- [**1-5**] blood culture bottles from admission tested positive for +enterococcus. ID service was consulted, who felt that this was +likely a contaminant. CT abdomen and pelvis was done, which +showed no abscesses or specific source of bacteremia. +- Further blood cultures were sent, and were negative to date at +the time of discharge. The final results should be followed up +by the rehab facility. +- C. diff was checked twice, both times negative. Given her high +risk for c. diff and loose stools, it was again checked on [**3-9**], +and the result is pending. It should be followed up by the rehab +facility. +. +# Shock: Patient had fever, hypoxia, and hypotension on +presentation. Most likely this is septic shock secondary to +pna. Less likely cardiogenic (CK is flat, EKG without ischemic +changes). Could also have component of central adrenal +insufficiency given pituitary macroadenoma (eos not elevated or +absent). +- Early goal directed therapy was implemented +- Lactate level was followed which peaked at 3.0 and was 1.9 on +[**3-8**]. +- MI was ruled out with negative cardiac enzymes +- cortisol level was checked (38.3 in AM) +. +# Neuro/ AMS: h/o right ACA stroke recently. Pt is rarely +responsive to voice. Opens eyes to noxious stimuli. There may be +a component of delirium in addition to residual deficits from +the large stroke recently. +- Medication list was reviewed and pared down to minimize risk +of drug effects +- Continued asa and statin +. +# Hypertension: Her home antihypertensives included metoprolol +and lisinopril. They were held in the beginning of her hospital +stay due to hypotension, then restarted slowly when she became +hypertensive. Metoprolol and lisinopril can be titrated up in +the rehab depending on her BP curve. +. +# Thyroid: Pt with goiter and low TSH in setting of pit +macroadenoma; Free T4 was WNL. +. +# anemia: at baseline of mid 20s. Hct was followed. She did not +require transfusions. +. +# hypocalcemia (even when corrected for low albumin) on +admission: unclear cause, however it resolved spontaneously. +Ionized calcium was WNL and stable. +. +# FEN: IVF PRN, replete electrolytes, TF per NG tube +. +# Prophylaxis: Subcutaneous heparin +# Access: PICC line. A line was discontinued. +# Code: Full +# Communication: Patient's family (daughter and grandson) + + +Medications on Admission: +1. Aspirin 325 mg qd +2. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H prn +3. Docusate Sodium 100 [**Hospital1 **] +4. Simvastatin 20mg qd +5. Lisinopril 5 mg qd +6. Metoprolol Tartrate 25 mg tid + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 459**] for the Aged - MACU + +Discharge Diagnosis: +Primary diagnoses: +Aspiration Pneumonia +Right ACA CVA + +Secondary Diagnoses: +HTN +Pituitary macroadenoma +Alzheimer's Dementia +Hyponatremia +Hypothyroidism +Anemia of chronic disease + +Discharge Condition: +Fair, VSS, afebrile, responsive to painful stimuli only. + +Discharge Instructions: +You were treated for your pneumonia. You also have had a stroke. +You should not + + +Completed by:[**2127-3-9**]",18,2127-03-03 19:58:00,2127-03-09 14:29:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,PNEUMONIA," +89f with shock and respiratory failure likely from pna. +. +# respiratory failure: patient was hypoxic with cxr showing +multifocal right lobe infiltrate. patient had recent aca stroke +and failed speach and swallow and not thought to be a good +candidate for tube feeds but the family wanted to continue to +feed her, putting her at high risk for aspiration. she was +intubated on presentation to the hospital and then extubated +successfully on [**2127-3-6**]. +- pt was started on vanco/zosyn for hap given recent hospital +stay and current living situation in the rehab. pt received 6 +days of vancomycin, after which it was discontinued. zosyn was +continued and pt should complete a course of 14 days (day +1=[**3-3**]) +- on discharge, pt was satting in high 90s to 100 on fio2 of +35%. +- sputum gram stain showed less than 25 pmns and culture grew +rare yeast. +- urine legionella was negative. +- bronchoalveolar lavage sample showed 4+ pmns, cmv culture +negative to date, andrespiratory cultures negative. +- [**1-5**] blood culture bottles from admission tested positive for +enterococcus. id service was consulted, who felt that this was +likely a contaminant. ct abdomen and pelvis was done, which +showed no abscesses or specific source of bacteremia. +- further blood cultures were sent, and were negative to date at +the time of discharge. the final results should be followed up +by the rehab facility. +- c. diff was checked twice, both times negative. given her high +risk for c. diff and loose stools, it was again checked on [**3-9**], +and the result is pending. it should be followed up by the rehab +facility. +. +# shock: patient had fever, hypoxia, and hypotension on +presentation. most likely this is septic shock secondary to +pna. less likely cardiogenic (ck is flat, ekg without ischemic +changes). could also have component of central adrenal +insufficiency given pituitary macroadenoma (eos not elevated or +absent). +- early goal directed therapy was implemented +- lactate level was followed which peaked at 3.0 and was 1.9 on +[**3-8**]. +- mi was ruled out with negative cardiac enzymes +- cortisol level was checked (38.3 in am) +. +# neuro/ ams: h/o right aca stroke recently. pt is rarely +responsive to voice. opens eyes to noxious stimuli. there may be +a component of delirium in addition to residual deficits from +the large stroke recently. +- medication list was reviewed and pared down to minimize risk +of drug effects +- continued asa and statin +. +# hypertension: her home antihypertensives included metoprolol +and lisinopril. they were held in the beginning of her hospital +stay due to hypotension, then restarted slowly when she became +hypertensive. metoprolol and lisinopril can be titrated up in +the rehab depending on her bp curve. +. +# thyroid: pt with goiter and low tsh in setting of pit +macroadenoma; free t4 was wnl. +. +# anemia: at baseline of mid 20s. hct was followed. she did not +require transfusions. +. +# hypocalcemia (even when corrected for low albumin) on +admission: unclear cause, however it resolved spontaneously. +ionized calcium was wnl and stable. +. +# fen: ivf prn, replete electrolytes, tf per ng tube +. +# prophylaxis: subcutaneous heparin +# access: picc line. a line was discontinued. +# code: full +# communication: patients family (daughter and grandson) + + + ","PRIMARY: [Pneumonitis due to inhalation of food or vomitus] +SECONDARY: [Acute respiratory failure; Septic shock; Severe sepsis; Hyposmolality and/or hyponatremia; Alkalosis; Hypocalcemia; Anemia in chronic kidney disease; Unspecified essential hypertension; Alzheimer's disease; Dementia in conditions classified elsewhere without behavioral disturbance; Benign neoplasm of pituitary gland and craniopharyngeal duct; Unspecified acquired hypothyroidism; Other late effects of cerebrovascular disease; Long-term (current) use of aspirin]" +43529,172162.0,16873,2115-09-26,16872,194815.0,2115-08-23,Discharge summary,"Admission Date: [**2115-8-20**] Discharge Date: [**2115-8-23**] + +Date of Birth: [**2032-12-31**] Sex: M + +Service: MEDICINE + +Allergies: +Ace Inhibitors / Norvasc + +Attending:[**First Name3 (LF) 106**] +Chief Complaint: +dyspnea + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +82M with CAD, chronic diastolic CHF, AFib on coumadin admitted +with dyspnea. Three days ago patient notes that he was not +feeling well. He was more fatigued than usual and had shortness +of breath with walking. He did not have palpitations, chest +pain, fevers, chills, orthopnea, pnd, worse edema than baseline +(has had chronic LE edema X 5 years), syncope, or presyncope. At +about 3 am on the morning of admission he awoke to turn down the +AC because he was chilly. When he sat up he became acutely short +of breath. His wife was able to calm him down and when he lay +back down he felt better. However, over the course of the next +few hours he started to feel more and more short of breath, even +when lying down, and by 7am his wife was very concerned. She +noticed that when she tried to stand him up to walk to the +living room he was very weak and his legs were wobbly. She +called 911, and they brought him to the ED. +. +Upon presentation to the ED initial vitals were: T 98 HR 76 BP +179/68 RR 28 SP02 98%RA. In the ED patient denied CP, fever, +chills, cough, weight gain. His O2 sats declined from 98% on RA +->91% on 4L->96% on NRB. CXR showed mild fluid overload and +possible PNA. Bedside TTE revealed: LA is moderately dilated. +There is mild symmetric left ventricular hypertrophy. The left +ventricular cavity size is normal. Overall left ventricular +systolic function is normal (LVEF 70%). There is no ventricular +septal defect. Right ventricular chamber size and free wall +motion are normal. The ascending aorta is mildly dilated. There +are focal calcifications in the aortic arch. The aortic valve +leaflets (3) are mildly thickened but aortic stenosis is not +present. No aortic regurgitation is seen. The mitral valve +leaflets are mildly thickened. There is no mitral valve +prolapse. Mild (1+) mitral regurgitation is seen. The estimated +pulmonary +artery systolic pressure is normal. There is no pericardial +effusion. +. +Compared with the findings of the prior study (images reviewed) +of [**2112-4-11**], the findings are similar. +. +He received the following medications: Aspirin 81mg, CeftriaXONE +1g, Azithromycin 500mg, Nitroglycerin SL 0.4mg SLX3 (for HF not +for complaints of CP), and Furosemide 80mg IV X 1. He felt +better after the furosemide (he put out 500mL) and his O2 +requirement came down to 94% on 4L. He was transferred to the +floor. +. +On the floor patient remained on NC and then on first set of +vitals was noted to be hypoxic to the mid-80s on 5L NC. He was +placed on a NRB and his O2 sat came up to 100%. He had no +complaints of chest pain, palpitations, shortness of breath, +abdominal pain, nausea, vomiting, or cough at the time. His EKG +was unchanged from prior. A CXR was also unchanged. ABG showed +an elevated A-a gradient with PO2 103 on the NRB. He was given +another 80mg IV lasix, morphine, and started on nitro paste. +Intially he improved with this regimen, however, he would +occasionally dip into the high 80s and then recover +spontaneously on the NRB and they were unable to wean him off +the NRB. He was transferred to the CCU for his continued +requirement of the NRB. +. +On presentation to the ccu the patient was comfortable on a NC. +He denied fevers, chills, palpitations, chest pain, nausea, +vomiting, diaphoresis, abdominal pain, bloating, worsening +edema, weight gain, diarrhea, and dysuria. He endorsed shortness +of breath as outlined above although currently less than prior, +constipation off and on for several years, and chronic edema of +his lower extremities for the last 5 years - treated with lasix. + + + +Past Medical History: +1. CARDIAC RISK FACTORS: hypertension, dyslipidemia. +2. CARDIAC HISTORY: +-CABG: None +-PERCUTANEOUS CORONARY INTERVENTIONS: s/p PTCA x1 15 years ago +records not at the [**Hospital1 18**] +-PACING/ICD: none +3. OTHER PAST MEDICAL HISTORY: +GASTRITIS +H.pylori + (treated) +GOUT +SYNCOPE +RENAL INSUFFICIENCY (creat ~ 1.6) +VENOUS INSUFFICIENCY and lower extremity edema +BENIGN PROSTATIC HYPERTROPHY +ATRIAL FIBRILLATION +diastolic dysfunction with volume overload treated with lasix +RETINAL VASCULAR OCCLUSION in [**2115-4-19**] thought [**1-21**] plaque +rupture not thrombotic event as therapeutic on coumadin at the +time + + +Social History: +Originally from Poland. Worked in [**Doctor First Name 533**] labor camp for a few +years before emmigrating. Also was in the service in the US. +Lives in [**Location **], MA with his wife. [**Name (NI) 1139**] history: Former 15 +pack-year smoker, quit 60 years ago. Rare ETOH use. No recent +travel. No sick contacts. + + +Family History: +No family history of early MI, arrhythmia, cardiomyopathies, or +sudden cardiac death; otherwise non-contributory + +Physical Exam: +PE on admission: + +V/S: Wt 89.4 kg T 99.5->102 ax BP 170/71 HR 70 RR 22 O2sat 94%6L + NC +GENERAL: WDWN M in NAD. Mood, affect appropriate. +HEENT: NCAT. Sclera anicteric. Conjunctiva were pink, no pallor +or cyanosis of the oral mucosa. No xanthalesma. +NECK: Supple with JVP to angle of jaw +CARDIAC: PMI located in 5th intercostal space, midclavicular +line. irregularly irregular with distant heart sounds. No m/r/g. + +LUNGS: Resp were unlabored, no accessory muscle use. Scattered +expiratory wheezes with poor air movement bilaterally and +crackles about [**12-22**] of the way up bilaterally. +ABDOMEN: Soft, NTND. No HSM or tenderness. Abd aorta not +enlarged by palpation. No abdominial bruits. Umbilical hernia +without tenderness. +EXTREMITIES: 1+ edema bilaterally to knees. Negative homans +sign. +NEURO: Alert and oriented X 3. Right pupil larger than left. +Left arm slightly weaker than right. + +PE on discharge: +V/S: Tmax 99, Tc 97.5, BP 154/69 (130-157/59-69) HR 65 (55-83) +RR 16 O2sat 94%RA +GENERAL: elderly white male in NAD. Mood, affect appropriate. +HEENT: NCAT. Sclera anicteric. PERRLA, Conjunctiva pink, OP +clear with no erythema or exudate +NECK: Supple with JVP to angle of jaw +CARDIAC: PMI located in 5th intercostal space, midclavicular +line. irregularly irregular with distant heart sounds. No m/r/g. + +LUNGS: Resp unlabored, no accessory muscle use. scatttered +rales at left base. +ABDOMEN: + BS, Soft, NTND. No HSM. Umbilical hernia without +tenderness. +EXTREMITIES: Trace edema in LE b/l, no cyanosis or clubbing +NEURO: Alert and oriented X 3. Right pupil larger than left. +Left arm slightly weaker than right. + + +Pertinent Results: +On Admission: +. +[**2115-8-20**] 08:05AM BLOOD WBC-8.7# RBC-3.99* Hgb-10.7* Hct-34.4* +MCV-86 MCH-26.8* MCHC-31.1 RDW-16.1* Plt Ct-214 +[**2115-8-20**] 08:05AM BLOOD PT-20.1* PTT-32.0 INR(PT)-1.9* +[**2115-8-20**] 08:05AM BLOOD Glucose-172* UreaN-45* Creat-1.7* Na-139 +K-4.1 Cl-101 HCO3-23 AnGap-19 +[**2115-8-20**] 08:05AM BLOOD CK-MB-NotDone proBNP-2736* +[**2115-8-20**] 08:05AM BLOOD cTropnT-0.06* +[**2115-8-21**] 05:43AM BLOOD Calcium-8.8 Phos-3.9 Mg-1.7 +[**2115-8-20**] 03:35PM BLOOD TSH-0.43 +[**2115-8-20**] 05:00PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.006 +[**2115-8-20**] 05:00PM URINE Blood-MOD Nitrite-NEG Protein-30 +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-NEG pH-7.0 Leuks-NEG +[**2115-8-20**] 05:00PM URINE RBC-[**11-8**]* WBC-0-2 Bacteri-MOD Yeast-NONE +Epi-0 +. +On discharge: +[**2115-8-23**] 05:35AM BLOOD WBC-6.6 RBC-3.74* Hgb-9.9* Hct-31.6* +MCV-85 MCH-26.6* MCHC-31.5 RDW-16.8* Plt Ct-265 +[**2115-8-23**] 05:35AM BLOOD PT-27.5* PTT-41.0* INR(PT)-2.7* +[**2115-8-23**] 05:35AM BLOOD Glucose-127* UreaN-60* Creat-1.5* Na-142 +K-4.0 Cl-105 HCO3-28 AnGap-13 +[**2115-8-23**] 05:35AM BLOOD Calcium-8.9 Phos-3.5 Mg-3.2* +. +Urine culture [**8-20**] negative +Blood cultures 9/1 and [**8-21**] NGTD +Legionella urine antigen neg [**8-20**] +. +TTE [**8-20**]: The left atrium is mildly dilated. The left ventricular +cavity size is top normal/borderline dilated. Overall left +ventricular systolic function is normal (LVEF>55%). [Intrinsic +left ventricular systolic function is likely more depressed +given the severity of valvular regurgitation.] There may be +inferolateral hypokinesis but views are technically suboptimal. +Right ventricular chamber size is normal. with normal free wall +contractility. The aortic valve leaflets (3) are mildly +thickened. No aortic regurgitation is seen. The mitral valve +leaflets are mildly thickened. An eccentric, laterally directed +jet of moderate to severe (3+) mitral regurgitation is seen. +There is severe pulmonary artery systolic hypertension. There is +no pericardial effusion. +Compared with the prior study (images reviewed) of [**2113-11-23**], +mitral regurgitation is now more prominent. There may be +inferolateral hypokinesis in the current study but images are +technically suboptimal for assessment of regional wall motion. +The left ventricular cavity is now more dilated. +. +Portable CXR [**8-20**]: Bilateral perihilar opacities may represent +congestive heart failure versus pneumonia. In the setting of the +patient's elevated BNP, findings more likely represent moderate +congestive heart failure. +. +Repeat Portable CXR [**8-20**]: +Stable appearance with bilateral perihilar airspace opacities. +Mild +cardiomegaly. +. +Portable CXR [**8-21**]: + In comparison with the study of [**8-20**], there is little overall +change +in the bilateral lower lung and left perihilar patchy +opacifications, +consistent with multifocal pneumonia. +. +Lower extremity dopplers [**8-21**]: No evidence of deep vein +thrombosis in either leg. [**Hospital Ward Name 4675**] cyst seen in the right +popliteal fossa. + +Brief Hospital Course: +ASSESSMENT AND PLAN: 82 year old man with history of CAD s/p +PCTA 15 years ago, diastolic CHF with history of fluid overload +on lasix, atrial fibrillation on coumadin with recent admission +for retinal occlusion, admitted with dyspnea on exertion, +hypoxia, and fever and transferred to the ICU due to increasing +oxygen requirements. +. +# Hypoxia: Likely this is multifactorial in etiology, from both +pulmonary and cardiac sources. He presented with evidence of +volume overload on exam, on CXR, and with an elevated BNP. In +addition, he had a fever likely infiltrate on CXR thought to be +consistent with community acquired pneumonia. PE was also a +consideration, but felt to be less likely because he was +anticoagulated on coumadin and had other more likely etiologies +for his hypoxia ([**Doctor Last Name **] score 4). Consequently, he was treated +for community acquired pneumonia with azithromycin and +ceftriaxone/cefpodoxime for a total five day course to end on +[**2115-8-24**]. In addition, TTE showed new LV dilation likely causing +more severe MR [**First Name (Titles) **] [**Last Name (Titles) **] with preserved LVEF (although this is +likely over-estimated in MR) consistent with acute exacerbation +of his diastolic CHF. He was diuresed with furosemide over the +course of his admission, and his noninvasive oxygen requirements +declined; he was able to maintain oxygen saturation in the high +90s at room air on discharge. +. +# Fever: Most likely infectious with either pulmonary or urinary +infection being most probable given leukocytosis, positive UA +and hypoxia with CXR showing possible infiltrate. Blood and +urine cultures NGTD, unable to obtain sputum culture. Treated +for both UTI and CAP; initially with ceftriaxone and +azithromycin, and transitioned to cefpodoxime with plan for +total five day course to end [**2115-8-24**]. +. +# CORONARIES: Patient with remote history of CAD s/p PTCA at OSH +and his tropinins were slightly elevated troponins with a peak +of 0.19 on [**2115-8-21**], flat CKs and negative MBs in the setting of +CRF. Cardiac enzymes were thought to be most likely elevated +from fluid overload and ventricular dilatation, and not cleared +secondary to renal failure. The patient denied any anginal +symptoms, and serial ECGs were not suggestive of any acute +ischemia. He was continued on home dose of statin, and started +on aspirin 81 mg PO daily. Per history, he is unable to tolerate +beta blockers and ace inhibitors. +. +# PUMP: Patient has history of diastolic dysfunction and has had +episodes of fluid overload treated with oral lasix in the past. +TTE on this admission revealed new LV dilation and worsening of +his MR with pulmonary artery hypertension, likely related to his +acute fluid overload. He was treated with aggressive diuresis, a +salt restricted diet and continuation of home blood pressure +regimen for afterload reduction with felodipine, hydralazine, +clonidine and Imdur. +. +# RHYTHM: The patient was monitored on telemetry and was found +to be intermittently in slow atrial fibrillation, with some ECGs +showing sinus bradycardia with prolonged AV conduction and +occasional junctional escape beats. The patient is on coumadin +for atrial fibrillation at home, and was found to be +subtherapeutic on admission. He also had a recent history of +retinal artery occlusion while anticoagulated. For that reason, +he was maintained on a heparin drip until INR was again +therapeutic. In addition, his coumadin was decreased from 5 to +2.5 on [**8-22**], with a plan to return to home dose of 5 mg on [**8-25**] +after he has finished his course of antibiotics. +. +# Hypertension: Patient's BP was 170/70 at recent PCP visit and +has been dificult to control according to OMR notes for last +several years. He is unable to tolerate ACE inhibitors or beta +blockers. During this admission, he was maintained on his home +regimen with hydralazine, clonidine, felodipine and Imdur. +. +# Lower extremity edema: Thought to be related to fluid overload +from acute on chronic diastolic CHF. LE dopplers on [**8-21**] were +negative for DVT. +. +# Chronic renal insufficiency: Patient remained at or below his +baseline creatinine of 1.7 during the course of the admission. +. +# Hyperlipidemia: Continued home dose of statin. +. +# Gout: Continued home dose of allopurinol +. +# CODE: DNR/DNI confirmed on admission with patient and family + + +Medications on Admission: +ALLOPURINOL 300 mg daily +CLONIDINE 0.1 mg twice daily +FELODIPINE 10 mg daily +FUROSEMIDE 80 mg daily +HYDRALAZINE 150 mg TID +IMDUR 60 mg daily +SIMVASTATIN 40 mg daily +WARFARIN 5 mg daily + + +Discharge Medications: +1. Isosorbide Mononitrate 60 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO DAILY (Daily). +2. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Hydralazine 50 mg Tablet Sig: Three (3) Tablet PO three times +a day. +4. Felodipine 10 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO once a day. +5. Clonidine 0.1 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +6. Allopurinol 300 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +7. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +8. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for fever. +9. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. +10. Azithromycin 250 mg Tablet Sig: One (1) Tablet PO Q24H +(every 24 hours) for 1 days. +Disp:*1 Tablet(s)* Refills:*0* +11. Cefpodoxime 100 mg Tablet Sig: Two (2) Tablet PO Q12H (every +12 hours) for 1 days. +Disp:*4 Tablet(s)* Refills:*0* +12. Warfarin 2.5 mg Tablet Sig: One (1) Tablet PO Once Daily at +4 PM. +13. Outpatient Lab Work +Please check INR on Sunday [**2115-8-25**] and call results to Dr. [**Name (NI) 47530**] office at [**Telephone/Fax (1) 1144**] +14. Furosemide 40 mg Tablet Sig: Two (2) Tablet PO once a day. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] Home Health Care + +Discharge Diagnosis: +Primary Diagnosis: +Community Acquired Pneumonia +Secondary Diagnosis: +Acute on Chronic Diastolic Chronic Congestive Heart Failure +Atrial Fibrillation on coumadin +Coronary Arteryu Disease +Chronic Kidney Disease + + +Discharge Condition: +stable + + +Discharge Instructions: +You had a pneumonia that caused your oxygen level to be low and +you were admitted to the intensive care unit. Your fevers and +low oxygen resolved slowly with intravenous antibiotics. You are +now on oral antibiotics and will need to take them for one more +day. +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +or 6 pounds in 3 days. +Adhere to 2 gm sodium diet, information was given to you about +this. +. +Medication changes: +1. Start 1 baby aspirin daily +2. Continue Azithromycin until [**8-24**] +3. Continue Cefpodoxime until [**8-24**] +4. Take 2.5 mg of coumadin on [**8-24**], then resume 5 mg of coumadin +on [**8-25**]. +. +Please call Dr. [**Last Name (STitle) **] if you have fevers, increasing cough, +chest pain, trouble breathing, or any other concerning symptoms. +Please check your INR on Sunday [**2115-8-25**]. + + +Followup Instructions: +Cardiology: +Provider: [**Name10 (NameIs) 1918**] [**Name11 (NameIs) **], MD Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2115-9-19**] 3:40 +Provider: [**Name10 (NameIs) 1918**] [**Name11 (NameIs) **], MD Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2115-10-24**] 2:00 +Primary Care: +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1143**], MD Phone:[**Telephone/Fax (1) 1144**] Date/Time: +Thursday [**2115-8-29**] at 11:00am. +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 1143**], MD Phone:[**Telephone/Fax (1) 1144**] +Date/Time:[**2115-11-27**] 9:00 + + + +",34,2115-08-20 11:09:00,2115-08-23 14:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CONGESTIVE HEART FAILURE," +assessment and plan: 82 year old man with history of cad s/p +pcta 15 years ago, diastolic chf with history of fluid overload +on lasix, atrial fibrillation on coumadin with recent admission +for retinal occlusion, admitted with dyspnea on exertion, +hypoxia, and fever and transferred to the icu due to increasing +oxygen requirements. +. +# hypoxia: likely this is multifactorial in etiology, from both +pulmonary and cardiac sources. he presented with evidence of +volume overload on exam, on cxr, and with an elevated bnp. in +addition, he had a fever likely infiltrate on cxr thought to be +consistent with community acquired pneumonia. pe was also a +consideration, but felt to be less likely because he was +anticoagulated on coumadin and had other more likely etiologies +for his hypoxia ([**doctor last name **] score 4). consequently, he was treated +for community acquired pneumonia with azithromycin and +ceftriaxone/cefpodoxime for a total five day course to end on +[**2115-8-24**]. in addition, tte showed new lv dilation likely causing +more severe mr [**first name (titles) **] [**last name (titles) **] with preserved lvef (although this is +likely over-estimated in mr) consistent with acute exacerbation +of his diastolic chf. he was diuresed with furosemide over the +course of his admission, and his noninvasive oxygen requirements +declined; he was able to maintain oxygen saturation in the high +90s at room air on discharge. +. +# fever: most likely infectious with either pulmonary or urinary +infection being most probable given leukocytosis, positive ua +and hypoxia with cxr showing possible infiltrate. blood and +urine cultures ngtd, unable to obtain sputum culture. treated +for both uti and cap; initially with ceftriaxone and +azithromycin, and transitioned to cefpodoxime with plan for +total five day course to end [**2115-8-24**]. +. +# coronaries: patient with remote history of cad s/p ptca at osh +and his tropinins were slightly elevated troponins with a peak +of 0.19 on [**2115-8-21**], flat cks and negative mbs in the setting of +crf. cardiac enzymes were thought to be most likely elevated +from fluid overload and ventricular dilatation, and not cleared +secondary to renal failure. the patient denied any anginal +symptoms, and serial ecgs were not suggestive of any acute +ischemia. he was continued on home dose of statin, and started +on aspirin 81 mg po daily. per history, he is unable to tolerate +beta blockers and ace inhibitors. +. +# pump: patient has history of diastolic dysfunction and has had +episodes of fluid overload treated with oral lasix in the past. +tte on this admission revealed new lv dilation and worsening of +his mr with pulmonary artery hypertension, likely related to his +acute fluid overload. he was treated with aggressive diuresis, a +salt restricted diet and continuation of home blood pressure +regimen for afterload reduction with felodipine, hydralazine, +clonidine and imdur. +. +# rhythm: the patient was monitored on telemetry and was found +to be intermittently in slow atrial fibrillation, with some ecgs +showing sinus bradycardia with prolonged av conduction and +occasional junctional escape beats. the patient is on coumadin +for atrial fibrillation at home, and was found to be +subtherapeutic on admission. he also had a recent history of +retinal artery occlusion while anticoagulated. for that reason, +he was maintained on a heparin drip until inr was again +therapeutic. in addition, his coumadin was decreased from 5 to +2.5 on [**8-22**], with a plan to return to home dose of 5 mg on [**8-25**] +after he has finished his course of antibiotics. +. +# hypertension: patients bp was 170/70 at recent pcp visit and +has been dificult to control according to omr notes for last +several years. he is unable to tolerate ace inhibitors or beta +blockers. during this admission, he was maintained on his home +regimen with hydralazine, clonidine, felodipine and imdur. +. +# lower extremity edema: thought to be related to fluid overload +from acute on chronic diastolic chf. le dopplers on [**8-21**] were +negative for dvt. +. +# chronic renal insufficiency: patient remained at or below his +baseline creatinine of 1.7 during the course of the admission. +. +# hyperlipidemia: continued home dose of statin. +. +# gout: continued home dose of allopurinol +. +# code: dnr/dni confirmed on admission with patient and family + + + ","PRIMARY: [Congestive heart failure, unspecified] +SECONDARY: [Pneumonia, organism unspecified; Urinary tract infection, site not specified; Acute on chronic diastolic heart failure; Atrial fibrillation; Gout, unspecified; Hypertensive chronic kidney disease, unspecified, with chronic kidney disease stage I through stage IV, or unspecified; Chronic kidney disease, unspecified; Venous (peripheral) insufficiency, unspecified; Hypertrophy (benign) of prostate without urinary obstruction and other lower urinary tract symptom (LUTS); Other and unspecified hyperlipidemia; Hematuria, unspecified; Coronary atherosclerosis of native coronary artery; Long-term (current) use of anticoagulants]" +47733,175486.0,21693,2151-04-24,21692,162330.0,2151-03-28,Discharge summary,"Admission Date: [**2151-3-7**] Discharge Date: [**2151-3-28**] + +Date of Birth: [**2111-7-13**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 425**] +Chief Complaint: +VF arrest + +Major Surgical or Invasive Procedure: +Endotracheal intubation (now extubated) +Central venous line placement (now removed) +Femoral line placement (now removed) +Electrophysiology study with cardiac catheterization + + +History of Present Illness: +39M w/ pmh significant for ebstein's anomaly s/p tricuspid valve +reconstruction, right and left sided systolic congestive heart +failure, presenting with palpitations which awoke him from +sleep. The patient presented to the ED where he appeared pale +and was found to be in VT to the 230's. He began to experience +chest pain and was given amiodarone 150mg IV X1, followed by +amiodarone gtt. He became diaphoretic and was therefore given +etomidate and shocked with 200J. His rhythm then became fine +V-fib, he became unresponsive and apneic. CPR was initiated, +epinephrine given X1, CPR continued, shocked again at 360J, +returned to V-Tach @ 240, Intubated, returned to sinus rhyhthm, +aspirated vomitus. had right bronchus intubation and ETT was +pulled back in ED. Blood pressures dropped to 48/43, started on +levophed, pressure increased to 124/77. +. +On presentation to the CCU, the patient is intubated with +mottled skin, on levophed, neosynephrine and vasopressin, with +HR 85 and BP 125/77. + + +Past Medical History: +1. Ebstein anomaly, s/p tricuspid valve reconstruction +- moderate to severe tricuspid regurgitation +- right heart failure, RVEF 25% in [**6-17**] +2. ASD, s/p primary closure [**3-/2136**] +3. Left heart failure with evidence of noncompaction of LV, with + +LVEF 28% in [**6-17**] +4. Hyperlipidemia +5. Hypertension +6. Obstructive sleep apnea +7. Obesity +8. DVT +9. Superficial phlebitis +10. endocarditis w/ septic emboli to brain prior to Cardiac +surgery. + + +Social History: +Remote tobacco use, quit 5-6 years ago. Still smokes an +occasional cigar. No history of alcohol abuse but has occasional +drink. No illicit drugs. Patient works as the [**Hospital1 18**] fax machine +repairman. He is married with 1 biologic child, aged 9 months, 2 +older children from his wife's prior marriage + +Family History: +There is no family history of premature coronary artery disease +or sudden death. Father's family history is unknown, mother is +alive in her 60's + + +Physical Exam: +Date and time of exam: [**2151-3-7**] +General appearance: sedated, intubated, obese +Vital signs: per R.N. +Height: 72 Inch, 183 cm BP right arm: 95 / 67 mmHg +Weight: 100 kg T current: 99.6 Cm HR: 99 bpm RR: 32 insp/minO2 +sat: 93 % on Supplemental oxygen: 100% +Eyes: (Conjunctiva and lids: WNL) +Ears, Nose, Mouth and Throat: (Oral mucosa: WNL), (Teeth, gums +and palette: WNL) +Neck: (Jugular veins: Not visible), (Thyroid: WNL) +Back / Musculoskeletal: (Chest wall structure: WNL) +Respiratory: (Auscultation: diminished on left, rhonchi +bilaterally.) +Cardiac: (Rhythm: Regular), (Palpation / PMI: WNL), +(Auscultation: S1: WNL, S3: Absent, S4: Absent) +Abdominal / Gastrointestinal: (Bowel sounds: WNL), (Bruits: No), +(Pulsatile mass: No), (Hepatosplenomegaly: No) +Genitourinary: (WNL) +Femoral Artery: (Right femoral artery: No bruit), (Left femoral +artery: No bruit) +Extremities / Musculoskeletal: (Digits and nails: WNL), (Gait +and station: WNL), (Muscle strength and tone: WNL), (Dorsalis +pedis artery: Right: 1+, Left: 1+), (Posterior tibial artery: +Right: 1+, Left: 1+), (Edema: Right: 0, Left: 0) +Skin: (mottled abdomen, cyanotic extreemities.) + + + +Pertinent Results: +admission labs- + +[**2151-3-7**] 05:30AM BLOOD WBC-9.4 RBC-4.83 Hgb-14.9 Hct-44.4 MCV-92 +MCH-30.8 MCHC-33.5 RDW-14.0 Plt Ct-306 +[**2151-3-7**] 05:30AM BLOOD Neuts-57.6 Lymphs-35.6 Monos-4.5 Eos-1.9 +Baso-0.4 +[**2151-3-7**] 05:30AM BLOOD PT-16.7* PTT-30.4 INR(PT)-1.5* +[**2151-3-8**] 02:59PM BLOOD Fibrino-546* +[**2151-3-8**] 02:59PM BLOOD FDP-80-160* +[**2151-3-7**] 05:30AM BLOOD Glucose-185* UreaN-16 Creat-1.0 Na-133 +K-6.3* Cl-97 HCO3-26 AnGap-16 +[**2151-3-7**] 05:30AM BLOOD CK(CPK)-267* +[**2151-3-7**] 02:56PM BLOOD CK(CPK)-262* +[**2151-3-7**] 08:29PM BLOOD CK(CPK)-740* +[**2151-3-8**] 03:01AM BLOOD ALT-400* AST-448* LD(LDH)-586* AlkPhos-68 +TotBili-1.2 +[**2151-3-11**] 04:12AM BLOOD Lipase-200* +[**2151-3-7**] 05:30AM BLOOD CK-MB-6 +[**2151-3-7**] 05:30AM BLOOD cTropnT-<0.01 +[**2151-3-7**] 02:56PM BLOOD CK-MB-7 cTropnT-0.36* +[**2151-3-7**] 08:29PM BLOOD CK-MB-9 cTropnT-0.30* +[**2151-3-7**] 05:30AM BLOOD Calcium-8.6 Phos-4.6* Mg-2.1 +[**2151-3-8**] 08:21PM BLOOD Vanco-6.6* +[**2151-3-7**] 06:19AM BLOOD Type-ART pO2-71* pCO2-51* pH-7.24* +calTCO2-23 Base XS--5 Intubat-INTUBATED +[**2151-3-7**] 05:35AM BLOOD Glucose-165* Na-135 K-9.6* Cl-94* +calHCO3-25 +[**2151-3-7**] 06:19AM BLOOD Hgb-14.6 calcHCT-44 O2 Sat-90 COHgb-2 +MetHgb-0.2 +[**2151-3-7**] 06:19AM BLOOD freeCa-1.07* + +Select labs- + +[**2151-3-12**] 04:36AM BLOOD WBC-18.9*# RBC-4.13* Hgb-12.6* Hct-37.2* +MCV-90 MCH-30.5 MCHC-33.8 RDW-14.7 Plt Ct-307 +[**2151-3-8**] 02:59PM BLOOD PT-24.6* PTT-39.6* INR(PT)-2.5* +[**2151-3-9**] 03:33AM BLOOD Glucose-170* UreaN-48* Creat-3.2* Na-129* +K-4.4 Cl-96 HCO3-23 AnGap-14 +[**2151-3-9**] 03:33AM BLOOD ALT-1211* AST-1132* CK(CPK)-4046* +AlkPhos-53 TotBili-1.8* +[**2151-3-10**] 05:00AM BLOOD ALT-1286* AST-864* LD(LDH)-677* +AlkPhos-54 TotBili-1.7* +[**2151-3-11**] 04:12AM BLOOD Lipase-200* + +Reports- +head CT with and without contrast [**2151-3-7**] +IMPRESSION: +1. No acute intracranial pathology. +2. Encephalomalacia of the right occipital pole with associated +ex vacuo +dilatation of the right lateral ventricular occipital [**Doctor Last Name 534**] +suggestive of prior cerebral injury. +================================ +Chest CTA [**2151-3-7**] +IMPRESSION: +1. Small left pneumothorax, likely related to acute left rib +fractures. Other rib deformities are bilateral. +2. Bibasilar and peribronchial opacities, could be due to +massive aspiration, associated with atelectasis. +3. Severe cardiomegaly with marked enlargement of right atrium +and right +ventricle in this patient with known Ebstein malformation and +prior sternotomy for tricuspid plasty. +4. Mediastinal lipomatosis. +5. Venous shunt between the right and the middle hepatic veins, +could be due to old Budd-Chiari disease. Tiny filling defect in +the abnormal connection could be branching vessels or thrombus, +likely old. +. +================================ +[**2151-3-7**] CT chest +IMPRESSION: +1. No residual pneumothorax in the upper two-thirds of the +chest. One +residual air bubble in the mediastinum. No chest tube was +installed. +2. No other change since earlier today. +================================ +CT chest [**2151-3-13**]- IMPRESSION: +1. No evidence of intra-abdominal fluid collection. +2. Basal pulmonary consolidation with small pleural effusions. +3. Mediastinal lipomatosis. +4. Right adrenal myelolipoma. +5. Evidence of previous right hip AVN. +. +Echo with bubble study +No spontaneous echo contrast or thrombus is seen in the left +atrium/left atrial appendage or the right atrium/right atrial +appendage. The left and atrial and right appendage emptying +velocities are depressed (<0.2m/s). The intra-atrial septum is +thickened consistent with prior ASD closure surgery. No residual +atrial septal defect is seen by 2D or color Doppler. Left +ventricular wall thickness and cavity size are grossly normal. +The apex is heavily trabeculated. Systolic function could not be +adequately assessed. Th e systolic function appears depressed. +The right ventricular cavity is dilated with marked free wall +hypokinesis. There are simple atheroma in the descending +thoracic aorta to 45cm from the incisors. The descending aorta +is relatively small, but no coarctation or dissection is seen. +The aortic valve leaflets (3) appear structurally normal with +good leaflet excursion. No aortic regurgitation is seen. The +mitral valve appears structurally normal with trivial mitral +regurgitation. No mass or vegetation is seen on the mitral +valve. The tricuspid annular ring is identified and appears well +seated. Mild to moderate tricuspid regurgitation is seen. There +is no pericardial effusion. + +IMPRESSION: No atrial septal defect by 2D or color Doppler. Well +seated tricuspid annular ring with mild-moderate tricuspid +regurgitation. Severe right ventricular cavity enlargement with +depressed biventricular systolic function. +. +Cardiac MRI:Impression: +1. Normal left ventricular cavity size with globally depressed +systolic function. The LVEF was severely decreased at 28%. No MR +evidence of prior myocardial scarring/infarction although images +technically suboptimal. Prominent non-compacted left ventricular +myocardium that meet CMR criteria for non-compaction. +2. Abnormal and apically displaced tricuspid valve consistent +with Ebstein's anomaly. A tricuspid annulplasty ring was +present. Moderately depressed systolic function of the +functional right ventricle with RVEF at 25%. Abnormal septal +motion consistent with right ventricular pressure / volume +overload. Markedly dilated inferior vena cava and hepatic veins +consistent with elevated +right atrial pressure. +3. Mild aortic regurgitation. Moderate-to-severe tricuspid +regurgitation through tricuspid leaflets of functional right +ventricle. Severe tricuspid regurgitation through tricuspid +annulus of structural right ventricle. 4. The indexed diameters +of the ascending and descending thoracic aorta were +normal. The main pulmonary artery diameter index was normal. +5. Biatrial enlargement. +. +Chest x-ray [**2151-3-17**] - IMPRESSION: 1. Stable appearance of the +mediastinum and cardiac silhouette. 2. Status post extubation. +No evidence of atelectasis. +. +EKG [**2151-3-26**]- Sinus rhythm. The P-R interval is prolonged. Left +axis deviation. Right bundle-branch block with left anterior +fascicular block. There are Q waves in the inferior leads +consistent with prior infarction. There is an abnormal +precordial transition consistent with possible prior anterior +myocardial infarction. Low voltage in the precordial leads. +Compared to the previous tracing the P-R interval is longer. + + +Brief Hospital Course: +39M w/ pmh of ebstein's anomaly, s/p tricuspid valve +reconstruction, right and left sided systolic congestive heart +failure, presenting with unstable ventricular tachycardia, s/p +resuscitation with return to sinus tachycardia, s/p intubation +and extubation. +. +# Ventricular Tachycardia: Likely result of natural history of +ebstein anomaly. Patient underwent CPR and intubation with +return to normal sinus rhythm. Suppressed ectopy with +Amiodarone. Also started metoprolol for rate-control. Amiodarone +increased to 200mg TID. Had cardiac MRI with final read as +above. Patient then underwent EP study where they were unable to +induce ventricular fibrillation so unable to ablate. EP was +unable to place an ICD during this admission given recent +procedure and significant abnormal heart anatomy. Patient to +follow up with Dr. [**Last Name (STitle) **] in [**2-12**] weeks to discuss possible +ICD placement in the future. In addition, patient to have +monitor set up at home as per Dr. [**Last Name (STitle) **]. +. +#Respiratory Failure - Now resolved. Initially primarily +hypoxemic, with unclear etiology. Differential includes ARDS, +PNA/sepsis, shunt, and volume overload. Improvement with nitric +oxide suggested some shunt physiology, although intracardiac +shunt was not evident on TEE. Respiratory failure improved with +diuresis. Decreased Fi02 and PEEP and nitric oxide weaned off +with improved compliance. Methemaglobin negative. Multifactorial +secondary to CHF, OSA, and restrictive ventilation due to +habitus. Required mechanical ventilation from admission +(intubated during V Fib arrrest in ED), and extubated on +[**2151-3-16**], without difficulty. Since, patient has been satting +well on room air using CPAP at night. +. +#Hypotension (resolved): Initially secondary to VT, in addition +probably contribution from sedatives, positive pressure +ventilation especially in the setting of marked RV dysfunction. +[**Month (only) 116**] also be intravscularly volume depleted, but total body +overloaded. Sepsis less likely at this point, given broad +spectrum antibiotic coverage, negative culture data, although +stil febrile. Patient initially on 3-pressors which were weaned +off. In terms of sepsis work-up all culture data negative, +although patient was treated empirically for VAP. Initially +held all blood pressure medications including beta blocker and +ACE inhibitor which were restarted slowly after hypotension had +resolved. +. +# Fevers: Leukocytosis/fever/right lobe infiltrate- Patient felt +to have likely aspiration PNA with witnessed emesis during +intubation. Cultures were all negative. Femoral line was +removed and sent for culture. Given negative culture data, +patient was treated for VAP and then there was concern that +possible drug fever given persistant fever and no positive +culture data. Fevers improved after patient was extubated and +did not recur. +. +# Chronic Systolic Congestive Heart Failure: Has right sided +heart failure only, s/p tricuspid reconstruction and ASD repair. +Patint on low dose metoprolol and lisinopril as above, cont +aspirin 325. Initially held statin in the setting of worsening +liver abnormalities but restarted as LFTs improved. Continued +patient's outpatient lasix dose of 40 mg Po daily once blood +pressures had improved. +. +# Pain: has left sided chest wall pain [**3-15**] fractured ribs from +resuscitation. Patient was treated with Lidocaine patch daily +as well as standing Tylenol. Patient was discharged on tylenol +PRN. +. +#Gout: Patient as outpatient on colchicine and allopurinol +although patient not taking allopurinol at home. Initially +concern that fever may be secondary to gout. Patient was tapped +and tap revealed WBC, Joint Fluid 300* #/uL 0 - 150 +RBC, Joint Fluid [**Numeric Identifier 1871**]* #/uL 0 - 0 Polys 80* % 0 - 25 +Lymphocytes 4 % 0 - 75 +Monocytes 0 % 0 - 70 Macrophage 16 % 0 - 70 FEW SIDEROTIC +GRANULES PRESENT +Joint Crystals, Number NO[**Serial Number **]. Patient states that he is having +pain in his right knee which he thinks is from his gout. Given +improvement in renal function and patient's request restarted +colchicine at outpatient dose. +. +# Anemia - patient with Cr 31 currently previous baseline 41. +Patient has not had anemia labs checked. Added on anemia labs to +discharge labs. Patient will require active type and screen +prior to additional procedures +. +FEN: regular cardiac diet, replete lytes PRN +. +ACCESS: PIV +. +PROPHYLAXIS: hep sc, colace, senna, PPI daily + +CODE: Full Colde + + +Medications on Admission: +ALBUTEROL - 90 mcg Aerosol - ii puffs ih qid prn +ALLOPURINOL - 300 mg Tablet - 2 Tablet(s) by mouth daily +ATORVASTATIN - 20 mg Tablet - 1 Tablet(s) by mouth once a day +COLCHICINE - 0.6 mg Tablet - One Tablet(s) by mouth once a day +DIGOXIN - 125 mcg Tablet - 1 Tablet(s) by mouth daily +FLUTICASONE [FLOVENT HFA] - 220 mcg Aerosol - 2 puffs nasally +twice a day x two weeks +FUROSEMIDE - 40 mg Tablet - 1 Tablet(s) by mouth once a day +LISINOPRIL - 10 mg Tablet - 1 Tablet(s) by mouth once a day +METOPROLOL SUCCINATE [TOPROL XL] - 25 mg Tablet Sustained +Release +24 hr - 1 Tablet(s) by mouth once a day + + +Discharge Medications: +1. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*1* +2. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*1* +3. Furosemide 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Colchicine 0.6 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Atorvastatin 20 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +6. Metoprolol Tartrate 25 mg Tablet Sig: One (1) Tablet PO twice +a day. +Disp:*60 Tablet(s)* Refills:*2* +7. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO TID (3 times +a day). +Disp:*90 Tablet(s)* Refills:*2* +8. Albuterol 90 mcg/Actuation Aerosol Sig: One (1) Inhalation +four times a day as needed for shortness of breath or wheezing. + + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary: +Ventricular fibrillation arrest +. +Secondary: +Ebstein's anomaly +Chronic left heart failure +Hyperlipidemia +Hypertension +Obstructive sleep apnea +Gout + +Discharge Condition: +Good, hemodynamically stable, afebrile + +Discharge Instructions: +You were admitted after cardiac arrest. The arrest was most +likely caused by underlying rhythm abnormalities related to your +Ebstein's Anomaly. You were intubated for airway protection, and +finally extubated after your respiratory status improved. You +had fevers that resolved after extubation. As you improved +significantly, you were transferred to the floor from the ICU. +You were evaluated by an electrophysiology study, but no +ablatable source could be identified in your heart. You need to +follow-up in 2 weeks with Dr. [**Last Name (STitle) **] for further evaluation +and possible ICD placement. Please also follow-up as strongly +advised below. Dr. [**Last Name (STitle) **] is arranging for you to have an +outpatient cardionet or loop recorder at home after discharge. +. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs. +Adhere to 2 gm sodium diet +Fluid Restriction:1500ml +. +The following changes were made to your medications: +- We are stopping your digoxin as your have not been on it in +the hospital +-STOP Allopurinol for now, re-discuss with Dr. [**Last Name (STitle) **] +[**Name (STitle) **] Lisinopril to 2.5mg PO daily +-CHANGE Metoprolol to 25 mg PO BID +-START Amiodarone 200mg PO 3 times daily +-START Aspirin 325mg PO daily +. +If you experience any chest pain, shortness of breath, +palpitations, weakness, nausea, vomiting, dizziness, +lightheadedness, or have any other concerns please [**Name6 (MD) 138**] your MD +or return to the ED. + +Followup Instructions: +Please call to set up a follow-up appointment within 2 weeks +with Dr. [**Last Name (STitle) **] ([**Telephone/Fax (1) 2037**] for further evaluation for ICD +and monitoring of your cardiac status. +. +Please follow-up with the Adult Congenital Heart Clinic within 1 +month for further monitoring of your Ebstein's anomaly. +. +Please call the rheumatology department ([**Telephone/Fax (1) 1668**] for a +follow up appointment with Dr. [**Last Name (STitle) **] to discuss when and if to +restart allopurinol treatment for gout. +. +Please follow-up with Sleep Medicine ([**Telephone/Fax (1) 9525**] to schedule +a repeat outpatient sleep study. +. +Please call the [**Hospital **] Clinic ([**Telephone/Fax (1) 7026**] as outpatient to +discuss weight loss in the case of further possible heart +surgery. We would reccomend you follow up within 1-2 weeks. + + +Completed by:[**2151-3-28**]",27,2151-03-07 06:24:00,2151-03-28 14:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CARDIAC ARREST," +39m w/ pmh of ebsteins anomaly, s/p tricuspid valve +reconstruction, right and left sided systolic congestive heart +failure, presenting with unstable ventricular tachycardia, s/p +resuscitation with return to sinus tachycardia, s/p intubation +and extubation. +. +# ventricular tachycardia: likely result of natural history of +ebstein anomaly. patient underwent cpr and intubation with +return to normal sinus rhythm. suppressed ectopy with +amiodarone. also started metoprolol for rate-control. amiodarone +increased to 200mg tid. had cardiac mri with final read as +above. patient then underwent ep study where they were unable to +induce ventricular fibrillation so unable to ablate. ep was +unable to place an icd during this admission given recent +procedure and significant abnormal heart anatomy. patient to +follow up with dr. [**last name (stitle) **] in [**2-12**] weeks to discuss possible +icd placement in the future. in addition, patient to have +monitor set up at home as per dr. [**last name (stitle) **]. +. +#respiratory failure - now resolved. initially primarily +hypoxemic, with unclear etiology. differential includes ards, +pna/sepsis, shunt, and volume overload. improvement with nitric +oxide suggested some shunt physiology, although intracardiac +shunt was not evident on tee. respiratory failure improved with +diuresis. decreased fi02 and peep and nitric oxide weaned off +with improved compliance. methemaglobin negative. multifactorial +secondary to chf, osa, and restrictive ventilation due to +habitus. required mechanical ventilation from admission +(intubated during v fib arrrest in ed), and extubated on +[**2151-3-16**], without difficulty. since, patient has been satting +well on room air using cpap at night. +. +#hypotension (resolved): initially secondary to vt, in addition +probably contribution from sedatives, positive pressure +ventilation especially in the setting of marked rv dysfunction. +[**month (only) 116**] also be intravscularly volume depleted, but total body +overloaded. sepsis less likely at this point, given broad +spectrum antibiotic coverage, negative culture data, although +stil febrile. patient initially on 3-pressors which were weaned +off. in terms of sepsis work-up all culture data negative, +although patient was treated empirically for vap. initially +held all blood pressure medications including beta blocker and +ace inhibitor which were restarted slowly after hypotension had +resolved. +. +# fevers: leukocytosis/fever/right lobe infiltrate- patient felt +to have likely aspiration pna with witnessed emesis during +intubation. cultures were all negative. femoral line was +removed and sent for culture. given negative culture data, +patient was treated for vap and then there was concern that +possible drug fever given persistant fever and no positive +culture data. fevers improved after patient was extubated and +did not recur. +. +# chronic systolic congestive heart failure: has right sided +heart failure only, s/p tricuspid reconstruction and asd repair. +patint on low dose metoprolol and lisinopril as above, cont +aspirin 325. initially held statin in the setting of worsening +liver abnormalities but restarted as lfts improved. continued +patients outpatient lasix dose of 40 mg po daily once blood +pressures had improved. +. +# pain: has left sided chest wall pain [**3-15**] fractured ribs from +resuscitation. patient was treated with lidocaine patch daily +as well as standing tylenol. patient was discharged on tylenol +prn. +. +#gout: patient as outpatient on colchicine and allopurinol +although patient not taking allopurinol at home. initially +concern that fever may be secondary to gout. patient was tapped +and tap revealed wbc, joint fluid 300* #/ul 0 - 150 +rbc, joint fluid [**numeric identifier 1871**]* #/ul 0 - 0 polys 80* % 0 - 25 +lymphocytes 4 % 0 - 75 +monocytes 0 % 0 - 70 macrophage 16 % 0 - 70 few siderotic +granules present +joint crystals, number no[**serial number **]. patient states that he is having +pain in his right knee which he thinks is from his gout. given +improvement in renal function and patients request restarted +colchicine at outpatient dose. +. +# anemia - patient with cr 31 currently previous baseline 41. +patient has not had anemia labs checked. added on anemia labs to +discharge labs. patient will require active type and screen +prior to additional procedures +. +fen: regular cardiac diet, replete lytes prn +. +access: piv +. +prophylaxis: hep sc, colace, senna, ppi daily + +code: full colde + + + ","PRIMARY: [Paroxysmal ventricular tachycardia] +SECONDARY: [Chronic systolic heart failure; Ebstein's anomaly; Acute respiratory failure; Pneumonitis due to inhalation of food or vomitus; Cardiogenic shock; Acute and subacute necrosis of liver; Acute kidney failure with lesion of tubular necrosis; Iatrogenic pneumothorax; Ventilator associated pneumonia; Congestive heart failure, unspecified; Hyposmolality and/or hyponatremia; Alkalosis; Closed fracture of two ribs; Cardiac arrest; Other iatrogenic hypotension; Other specified misadventures during medical care; Other and unspecified hyperlipidemia; Unspecified essential hypertension; Obstructive sleep apnea (adult)(pediatric); Mitral valve disorders; Obesity, unspecified; Anemia, unspecified; Venous (peripheral) insufficiency, unspecified; Gout, unspecified; Personal history of venous thrombosis and embolism; Personal history of thrombophlebitis; Other postprocedural status]" +49081,140192.0,14375,2161-11-27,14374,127653.0,2161-11-05,Discharge summary,"Admission Date: [**2161-10-18**] Discharge Date: [**2161-11-5**] + +Date of Birth: [**2099-7-2**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 3276**] +Chief Complaint: +dyspnea, low grade fever + +Major Surgical or Invasive Procedure: +pleurex catheter drainage +EGD + + +History of Present Illness: +Mr. [**Known lastname 42603**] is a 62 year old male with a h/o metastatic large +cell lung cancer to bone c/b recurrent malignant pleural +effusion requiring pleurex catheter placement, HIV (CD4 535) on +HAART, htn who presented to the ED with pleuritic CP and dyspnea +which has been his long standing issues. He further states that +he flt like he was dying and is not cmofortable with going home. +In ED vitals were stable with sats 100% on 1.5L o2 and bp of +134/89, temp 99.4. labs are at baseline. CXR revealed moderate +to large left sided pleural effusion with pleurex drain and +minimal interval changes. His temp subsequently went to 100.5 +although he [**Doctor First Name 1638**] any neck stiffness, photophobia, cough, +nausea, vomiting, diarrhoea, dysuria or rash. He was cultured +and started on vanco and zosyn. He's seen by psych who felt he's +not at suicidal risk. He's admitted for further care. + +Past Medical History: +[**7-/2159**]: Diagnosed with non small cell lung cancer by CT guided +biopsy +[**2159-9-20**]: PET scan with low-attenuation lesion in the left +lobe of the thyroid gland measuring 25 x 7 mm in addition to +markedly FDG avid left upper lobe mass consistent with known +cancer and FDG avid prominent bilateral axillary lymphadenopathy +suspicious for metastatic disease, but no pathologically +enlarged +infraclavicular lymph nodes. He also had retroperitoneal +internal and external iliac chain FDG avid lymphadenopathy +considered unusual for lung carcinoma. +[**2159-10-29**]: FNA of the thyroid, which was negative. +[**2159-10-31**]: Left axillary lymph node dissection. With pathology +revealing florid reactive follicular hyperplasia consistent with +HIV associated lymphadenopathy. Further staging and treatment +were deferred until the patient was stabilized on HAART therapy. + He was +initially seen by infectious disease doctors [**Last Name (NamePattern4) **] [**2160-1-10**] and +was started on HAART therapy in 01/[**2160**]. +[**3-/2160**]: He was hospitalized for influenza. After the +hospitalization, he was lost to follow up until [**Month (only) **]. Other +than the visit with his infectious disease on [**2160-5-5**], he then +lost to follow up until [**7-13**]. +[**2160-7-24**]: CT demonstrated left upper lobe mass minimally +increased in size from [**3-/2160**] with a sub 5 mm left upper lobe +pulmonary nodule +with additional stable bilateral nodules, new left-sided pleural +effusion. +[**2160-8-6**]: Bronchoscopy, mediastinoscopy, and pleural drainage +and talc pleurodesis by Dr. [**Last Name (STitle) **]. Pathology revealed 4R lymph +nodes with no malignancy but frozen sections showed metastatic +large cell carcinoma and 4L lymph nodes that showed metastatic +large cell carcinoma. A level 7 lymph node showed metastatic +large cell carcinoma and a parietal pleural biopsy also showed +metastatic large cell carcinoma involving the pleura. He was +started on carboplatin and +gemcitabine on [**2160-8-28**] he has completed 4 cycles. +[**2160-12-5**]: MR [**Name13 (STitle) **] with L1 lesion +. +MEDICAL HISTORY: +- Peripheral vestibulopathy +- HIV: Diagnosed in the [**2142**], he had been previously +cared for by Dr. [**First Name8 (NamePattern2) 333**] [**Last Name (NamePattern1) 42604**] at [**Hospital6 **]. +[**2160-10-30**] -> CD4 425, VL undetectable +- Positive PPD-negative AFB [**1-11**]-s/p 6 months Rifampin in +[**2148**]. +- Hypertension. +- History of appendicitis status post appendectomy in [**2126**]. + + +Social History: +He is originally of Haitian origin. His wife +and children live in [**Country 2045**]. He is an employee in the food +service industry here at [**Hospital1 18**]. He reports a prior history +of tobacco, having stopped in [**2148**]. He is sexually active only +with women. He denies any intravenous drug use. He received +transfusions potentially around the time of his appendectomy in +[**2126**]. + + +Family History: +No premature CAD or cancer. + +Physical Exam: +T: 97.6 BP: 122/89 HR: 100 RR: 20 O2 100% 2LNC +Gen: Pleasant, chronically ill appearing male in NAD +HEENT: No conjunctival pallor. No icterus. MMM. OP clear. +NECK: Supple. JVP low. +CV: RRR. nl S1, S2. No murmurs, rubs or [**Last Name (un) 549**] +LUNGS: Prominent breath sounds. Decreased on L halfway up. +ABD: NABS. Soft, NT, ND. No HSM +EXT: WWP, NO CCE. Full distal pulses bilaterally. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Moving all +extremities. + +Exam at discharge: +O: 126/88 99 99.1 98% RA 1154/1520 +Gen: Pleasant, chronically ill appearing male in NAD +HEENT: No conjunctival pallor. No icterus. MMM. OP clear. +NECK: Supple. JVP low. +CV: RRR. nl S1, S2. No murmurs, rubs or [**Last Name (un) 549**], mild chest +discomfort reproducible over sternum +LUNGS: Prominent breath sounds. Decreased on L halfway up. +ABD: NABS. Soft, NT, ND. No HSM +EXT: WWP, NO CCE. Full distal pulses bilaterally. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Appropriate. CN 2-12 grossly intact. Moving all +extremities. + +Pertinent Results: +[**2161-10-18**] WBC-10.7 Hgb-9.8* Hct-30.9* Plt Ct-577* +[**2161-10-19**] WBC-3.6*# Hgb-8.6* Hct-25.8* Plt Ct-397 +[**2161-10-19**] WBC-2.3* Hgb-9.6* Hct-29.3* Plt Ct-379 +[**2161-10-20**] WBC-1.5* Hgb-9.0* Hct-27.7* Plt Ct-319 +[**2161-10-21**] WBC-2.1* Hgb-9.1* Hct-27.4* Plt Ct-257 +[**2161-10-22**] WBC-2.9* Hgb-8.6* Hct-26.6* Plt Ct-220 +[**2161-10-23**] WBC-3.8* Hgb-8.9* Hct-27.3* Plt Ct-169 +[**2161-10-24**] WBC-3.9* Hgb-8.2* Hct-25.4* Plt Ct-167 +[**2161-10-24**] WBC-4.0 Hgb-8.5* Hct-26.9* Plt Ct-153 +[**2161-10-25**] WBC-4.5 Hgb-7.4* Hct-21.9* Plt Ct-178 +[**2161-10-26**] WBC-5.5 Hgb-7.9* Hct-24.0* Plt Ct-182 +[**2161-10-27**] WBC-6.4 Hgb-9.2* Hct-26.7* Plt Ct-172 +[**2161-10-28**] WBC-7.0 Hgb-9.8* Hct-28.6* Plt Ct-227 +[**2161-10-29**] WBC-8.5 Hgb-9.6* Hct-28.7* Plt Ct-279 +[**2161-10-30**] WBC-8.3 Hgb-9.4* Hct-29.7* Plt Ct-359 +[**2161-10-31**] WBC-7.8 Hgb-9.8* Hct-29.6* Plt Ct-458* +[**2161-11-1**] WBC-7.9 Hgb-9.3* Hct-28.5* Plt Ct-521* +[**2161-11-2**] WBC-5.8 Hgb-9.7* Hct-29.3* Plt Ct-595* +[**2161-11-4**] WBC-6.8 Hgb-9.3* Hct-29.4* Plt Ct-676* +[**2161-11-5**] WBC-7.5 Hgb-9.0* Hct-28.0* Plt Ct-656* + +[**2161-10-28**] WBC-7.0 Lymph-43* Abs [**Last Name (un) **]-3010 CD3%-78 Abs CD3-2339* +CD4%-16 Abs CD4-483 CD8%-61 Abs CD8-1824* CD4/CD8-0.3* + +[**2161-10-18**] UreaN-11 Creat-1.2 Na-136 K-4.6 Cl-96 HCO3-28 +AnGap-17 +[**2161-10-19**] UreaN-10 Creat-1.1 Na-139 K-3.8 Cl-102 HCO3-30 +AnGap-11 +[**2161-10-20**] UreaN-6 Creat-1.2 Na-140 K-3.7 Cl-103 HCO3-30 +AnGap-11 +[**2161-10-21**] UreaN-11 Creat-1.4* Na-142 K-3.8 Cl-102 HCO3-31 +AnGap-13 +[**2161-10-22**] UreaN-9 Creat-1.4* Na-141 K-3.7 Cl-100 HCO3-31 +AnGap-14 +[**2161-10-23**] UreaN-8 Creat-1.6* Na-141 K-4.0 Cl-104 HCO3-30 +AnGap-11 +[**2161-10-23**] UreaN-8 Creat-1.6* Na-138 K-3.9 Cl-100 HCO3-29 +AnGap-13 +[**2161-10-24**] UreaN-7 Creat-1.7* Na-139 K-3.6 Cl-101 HCO3-30 +AnGap-12 +[**2161-10-25**] UreaN-7 Creat-1.7* Na-138 K-4.0 Cl-100 HCO3-30 +AnGap-12 +[**2161-10-26**] UreaN-10 Creat-2.0* Na-139 K-4.0 Cl-100 HCO3-31 +AnGap-12 +[**2161-10-27**] UreaN-13 Creat-2.0* Na-140 K-4.2 Cl-103 HCO3-29 +AnGap-12 +[**2161-10-28**] UreaN-10 Creat-2.0* Na-141 K-4.0 Cl-102 HCO3-30 +AnGap-13 +[**2161-10-29**] UreaN-11 Creat-2.1* Na-143 K-4.0 Cl-105 HCO3-26 +AnGap-16 +[**2161-10-30**] UreaN-11 Creat-2.3* Na-143 K-4.2 Cl-105 HCO3-29 +AnGap-13 +[**2161-10-31**] UreaN-11 Creat-2.3* Na-141 K-4.2 Cl-105 HCO3-28 +AnGap-12 +[**2161-11-1**] UreaN-12 Creat-2.3* Na-143 K-4.3 Cl-105 HCO3-30 +AnGap-12 +[**2161-11-2**] UreaN-11 Creat-2.3* Na-145 K-4.3 Cl-105 HCO3-29 +AnGap-15 +[**2161-11-3**] UreaN-9 Creat-1.9* Na-143 K-4.1 Cl-104 HCO3-29 +AnGap-14 +[**2161-11-4**] UreaN-8 Creat-2.1* Na-147* K-4.3 Cl-108 HCO3-31 +AnGap-12 +[**2161-11-5**] UreaN-9 Creat-1.8* Na-145 K-4.2 Cl-105 HCO3-32 +AnGap-12 + +[**2161-10-24**] ALT-97* AST-89* LD(LDH)-505* CK(CPK)-97 AP-288* +Amylase-93 TotBili-5.1* +[**2161-10-24**] CK(CPK)-102 +[**2161-10-25**] ALT-79* AST-66* LD(LDH)-478* CK(CPK)-88 AP-246* +Amylase-80 TotBili-4.4* DirBili-0.2 IndBili-4.2 +[**2161-10-26**] ALT-64* AST-53* AP-244* TotBili-4.2* +[**2161-10-27**] ALT-50* AST-43* LD(LDH)-497* AP-227* Amylase-78 +TotBili-4.5* +[**2161-10-28**] ALT-41* AST-41* LD(LDH)-514* AP-230* TotBili-4.4* +[**2161-10-29**] ALT-37 AST-43* AP-236* TotBili-3.1* +[**2161-10-30**] ALT-58* AST-79* LD(LDH)-486* AP-406* TotBili-1.5 +[**2161-10-31**] ALT-44* AST-51* LD(LDH)-483* AP-371* TotBili-0.7 +[**2161-11-1**] ALT-45* AST-61* LD(LDH)-469* AP-402* TotBili-0.4 +[**2161-11-4**] ALT-86* AST-165* LD(LDH)-619* AP-465* TotBili-0.4 +[**2161-11-5**] ALT-59* AST-69* LD(LDH)-607* AP-409* TotBili-0.4 + +[**2161-10-24**] CK-MB-2 cTropnT-<0.01 +[**2161-10-24**] CK-MB-2 cTropnT-<0.01 +[**2161-10-25**] CK-MB-2 cTropnT-<0.01 +[**2161-10-28**] Type-ART pO2-92 pCO2-26* pH-7.66* calTCO2-30 Base XS-9 + +[**2161-10-28**] Type-ART pO2-26* pCO2-37 pH-7.53* calTCO2-32* Base +XS-6 +[**2161-10-29**] Type-[**Last Name (un) **] pO2-43* pCO2-47* pH-7.45 calTCO2-34* Base +XS-7 +[**2161-10-30**] Type-[**Last Name (un) **] pO2-154* pCO2-46* pH-7.45 calTCO2-33* Base +XS-7 C +[**2161-10-28**] Lactate-1.1 Na-143 K-3.7 Cl-102 +[**2161-10-28**] Lactate-2.1* Na-144 K-3.8 Cl-101 + +[**2161-10-21**] URINE Hours-RANDOM Creat-31 Na-31 K-13 Cl-30 +[**2161-10-24**] URINE Hours-RANDOM Creat-31 Na-24 +[**2161-10-28**] URINE Hours-RANDOM Creat-30 Na-49 K-16 Cl-39 +[**2161-10-30**] URINE Hours-RANDOM UreaN-126 Creat-45 Na-32 Phos-6.8 +[**2161-10-28**] URINE Osmolal-160 +[**2161-10-30**] URINE Osmolal-153 +[**2161-10-20**] PLEURAL WBC-600* RBC-8125* Polys-0 Lymphs-95* Monos-5* +[**2161-10-21**] PLEURAL WBC-889* RBC-[**Numeric Identifier 42605**]* Polys-1* Lymphs-89* +Monos-6* Eos-1* Meso-2* Macro-1* +[**2161-11-5**] PLEURAL WBC-650* RBC-[**Numeric Identifier 42606**]* Polys-7* Lymphs-91* +Monos-2* +[**2161-10-20**] PLEURAL TotProt-3.9 LD(LDH)-527 +[**2161-10-20**] PLEURAL TotProt-3.4 LD(LDH)-447 +[**2161-10-21**] PLEURAL TotProt-3.7 Glucose-119 LD(LDH)-430 + +CXR [**10-18**] +IMPRESSION: Moderate to large left pleural effusion with related +atelectasis +unchanged. Subtle consolidation on the left could be obscured +however the +right lung remains clear. + +CXR [**10-20**] +1. No pulmonary embolism. + +2. No significant change in moderate left pleural effusion. +While small +loculations of the effusion are associated, the pleural catheter +resides +within the largest pleural collection. Nodular thickening and +enhancement of the pleura may be secondary to metastatic +involvement versus iatrogenic +etiologies (i.e. pleurodesis). + +3. No significant change in left upper lobe pulmonary mass or +innumerable +lung metastases. Diffuse interlobular septal thickening may +again represent +lymphangitic spread of carcinoma. + +4. Persistant round atelectasis involving a large portion of the +left lower +lobe. + +CXR [**10-28**] +FINDINGS: As compared to the previous examination, there is no +relevant +change. The extent of the pre-existing left-sided pleural +effusion is +constant. The effusion fills more than 50% of the left +hemithorax and +distributes through the entirety of the pleural space. The +retrocardiac lung areas and the few ventilated left lung areas +are clearly atelectatic. + +There could be mild displacement of the heart over the midline +into the right hemithorax, probably exaggerated by a relatively +severe thoracic scoliosis. + +The right lung is free of effusions. However, mild overhydration +is seen. No evidence of pneumothorax, no focal parenchymal +opacities suggesting pneumonia. + +CXR [**10-31**] +IMPRESSION: Extensive left effusion; however, decreased compared +to [**2161-10-28**]. No new consolidations and no PTX. + +CT head [**10-28**] +1. Known pituitary/sellar mass is again identified, unchanged +but +incompletely evaluated. +2. No large mass lesion separate from this or area of +hemorrhage. Please +note that MRI is more sensitive in detection of small lesions +and can be +considered for assessment of metastatic disease. + +Renal ultrasound: No evidence of stones or hydronephrosis in +either kidney. Simple +cyst in the right kidney. + +Abdominal ultrasound [**11-4**] +1. Normal-appearing liver, with no intrahepatic lesion seen. +2. s/p cholecystectomy. The common duct is not dilated, and +there is no +intrahepatic biliary dilatation. + +ECHO: No vegetations +EGD: mucosal erythema c/w gastritis + +pleural fluid at discharge: +GRAM STAIN (Final [**2161-11-5**]): + 2+ (1-5 per 1000X FIELD): POLYMORPHONUCLEAR +LEUKOCYTES. + NO MICROORGANISMS SEEN. + This is a concentrated smear made by cytospin method, +please refer to + hematology for a quantitative white blood cell count.. + + FLUID CULTURE (Final [**2161-11-8**]): NO GROWTH. + + ANAEROBIC CULTURE (Preliminary): NO GROWTH + + +Brief Hospital Course: +62 year old male with a h/o metastatic large cell lung cancer to +bone c/b recurrent malignant pleural effusion requiring pleurex +catheter placement, HIV (CD4 535) on HAART, htn who presented +with dyspnea, unchanged pleural effusion on cxr and low grade +fever. + +# Coagulase negative staph in pleural fluid, urine: +Initially thought to be contaminant but grew in several samples +and then in urine. Blood cultures were all negative and an +echocardiogram showed no vegetations. The patient was treated +with levofloxacin and was afebrile. + +# Pleural effusion: Drained by IP frequently throughout +hospitalization usually followed by improvement in dyspnea. See +above for pleural fluid analysis at discharge. The patient will +continue to receive thrice weekly pleurex drainage via VNA at +home. + +# [**Last Name (un) **]: Likely contrast induced nephropathy though elevation +persisted longer than expected. Peaked at 2.3 and trending down +on discharge to 1.8. + +# Epigastric pain. Persistent nausea/vomiting and epigastric +pain. Ruled out for MI. Had EGD which showed gastritis. Path +from biopsy pending. Symptoms began to improve before discharge. + +# Tachypnea/Anxiety. Patient was transferred to MICU overnight +for tachypnea and respiratory alkalosis with pH of 7.6. It +resolved with ativan and morphine. A central drive for +respiratory alkalosis was ruled out by CT. He was started on [**Hospital1 **] +Klonipin with good effect. + +# Lung cancer: Plan per primary oncologist. + +# HIV. CD4 483. HAART was stopped for [**Last Name (un) **], elevated LFTs. He +will follow with HIV doctor as outpatient. + +# Hypertension: controlled well with amlodpine + +# Depression/suicidal ideation: iniatlly followed by pscyh for +question of suicidal ideation on admission but this appears to +have been a misunderstanding. They did recommend Celexa. This +was started at 10mg for one day but it was not continued as +patient was sent to the MICU on that day. + +Code- full + +Medications on Admission: +amlodipine 10 mg daily +atazanavir 300 mg daily +Truvada 200mg/300mg daily +ritonivir 100 mg daily +alimenta Q3weeks +folic acid 1 mg daily +ibuprofen 800 mg TID +morphine SR 15 mg [**Hospital1 **] +oxycodone 5-10 mg Q4H prn +ranitidine 150 mg daily +colace/senna +compazine 10 mg prn +lactulose prn +albuterol prn + +Discharge Medications: +1. Amlodipine 5 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +2. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Oxycodone 5 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 hours) +as needed for pain. +4. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed for wheeze. +5. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +6. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +7. Clonazepam 0.5 mg Tablet Sig: One (1) Tablet PO twice a day. +Disp:*30 Tablet(s)* Refills:*2* +8. Ranitidine HCl 150 mg Capsule Sig: One (1) Capsule PO once a +day. +9. Compazine 10 mg Tablet Sig: One (1) Tablet PO once a day as +needed for nausea. +Disp:*30 Tablet(s)* Refills:*0* +10. Lactulose 10 gram Packet Sig: One (1) PO once a day. +Disp:*30 packets* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +Primary Diagnosis: +metastatic large cell lung cancer +HIV/AIDS + +Secondary Diagnoses: +# stage IIIB large cell lung cancer metastatic to bone +- started Alimenta [**2161-7-16**] +# HIV, CD4 [**6-13**] 535, VL undetectable +- diagnosed in [**2142**] +- re-initiated HAART on [**2160-2-28**] +# chronic malignant pleural effusion s/p talc pleurodesis [**8-12**] +with pleurex catheter placed [**1-12**] for recurrent effusion +# Hypertension +# Positive PPD-negative AFB [**1-11**]-s/p 6 months Rifampin in [**2148**]. + +# Hepatitis B +# s/p cholecystectomy on [**2161-4-1**] +# h/o appendicitis status post appendectomy in [**2126**] +# Sellar mass seen on MRI most recently on [**2160-8-4**] +- a stable appearance of the intra and suprasellar mass +- nonfunctioning mass as worked up by endocrinology +# Low back pain + + + + +Discharge Condition: +stable and improved + + +Discharge Instructions: +You were admitted to the hospital for shortness of breath. Your +symptoms improved after some fluid was drained from the catheter +in your chest. A CT scan of your chest showed that you did not +have any blood clots in your lungs. You developed mild kidney +dysfunction during stay that improved with fluids. You also +developed abdominal pain during your hospitalization. An +endoscopic procedure showed that you had no inflammation in your +esophagous, and some mild inflammation in your stomach. +Biopsies were taken and we are still awaiting the results. An +ultrasound of your abdomen also was normal. You continued to +improve and you were discharged on [**2161-11-5**] home with services. + +The following changes have been made to your medications: +please do not take your HIV medications until you meet with Dr. +[**Last Name (STitle) 7443**]: +atazanavir +Truvada +ritonivir + +See below for follow up appointments. + +Please call your doctor or 911 if you develop worsening +shortness of breath, chest pain, fevers or chills, worsening +abdominal pain, persistent vomiting or diarrhea, or any other +concerning medical symptoms. + + +Followup Instructions: +[**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) 7447**], MD Phone:[**Telephone/Fax (1) 457**] Date/Time:[**2161-11-18**] 11:30 + +please call your primary oncologist, Dr. [**Last Name (STitle) 3274**], at +[**Telephone/Fax (1) 15512**], this week to set up a follow up appointment next +week + + + [**First Name8 (NamePattern2) 251**] [**Name8 (MD) **] MD [**MD Number(1) 3282**] + +",22,2161-10-18 18:44:00,2161-11-05 16:45:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,PLEURAL EFFUSION," +62 year old male with a h/o metastatic large cell lung cancer to +bone c/b recurrent malignant pleural effusion requiring pleurex +catheter placement, hiv (cd4 535) on haart, htn who presented +with dyspnea, unchanged pleural effusion on cxr and low grade +fever. + +# coagulase negative staph in pleural fluid, urine: +initially thought to be contaminant but grew in several samples +and then in urine. blood cultures were all negative and an +echocardiogram showed no vegetations. the patient was treated +with levofloxacin and was afebrile. + +# pleural effusion: drained by ip frequently throughout +hospitalization usually followed by improvement in dyspnea. see +above for pleural fluid analysis at discharge. the patient will +continue to receive thrice weekly pleurex drainage via vna at +home. + +# [**last name (un) **]: likely contrast induced nephropathy though elevation +persisted longer than expected. peaked at 2.3 and trending down +on discharge to 1.8. + +# epigastric pain. persistent nausea/vomiting and epigastric +pain. ruled out for mi. had egd which showed gastritis. path +from biopsy pending. symptoms began to improve before discharge. + +# tachypnea/anxiety. patient was transferred to micu overnight +for tachypnea and respiratory alkalosis with ph of 7.6. it +resolved with ativan and morphine. a central drive for +respiratory alkalosis was ruled out by ct. he was started on [**hospital1 **] +klonipin with good effect. + +# lung cancer: plan per primary oncologist. + +# hiv. cd4 483. haart was stopped for [**last name (un) **], elevated lfts. he +will follow with hiv doctor as outpatient. + +# hypertension: controlled well with amlodpine + +# depression/suicidal ideation: iniatlly followed by pscyh for +question of suicidal ideation on admission but this appears to +have been a misunderstanding. they did recommend celexa. this +was started at 10mg for one day but it was not continued as +patient was sent to the micu on that day. + +code- full + + ","PRIMARY: [Malignant pleural effusion] +SECONDARY: [Human immunodeficiency virus [HIV] disease; Pneumonia, organism unspecified; Acute kidney failure with lesion of tubular necrosis; Malignant neoplasm of upper lobe, bronchus or lung; Secondary malignant neoplasm of bone and bone marrow; Alkalosis; Mixed acid-base balance disorder; Hyperosmolality and/or hypernatremia; Other specified gastritis, without mention of hemorrhage; Staphylococcus infection in conditions classified elsewhere and of unspecified site, other staphylococcus; Vestibular neuronitis; Unspecified essential hypertension; Unspecified gastritis and gastroduodenitis, without mention of hemorrhage; Cyst of kidney, acquired; Lumbago; Unspecified adjustment reaction; Unspecified condition of brain; Esophageal reflux; Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]; Constipation, unspecified; Other drugs and medicinal substances causing adverse effects in therapeutic use; Depressive disorder, not elsewhere classified]" +51698,190004.0,23245,2142-03-09,23244,137588.0,2142-02-19,Discharge summary,"Admission Date: [**2142-2-13**] Discharge Date: [**2142-2-19**] + +Date of Birth: [**2072-4-9**] Sex: M + +Service: NEUROSURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 3227**] +Chief Complaint: +Headaches, emesis, altered mental status, right hemiparesis + +Major Surgical or Invasive Procedure: +[**2142-2-13**]: Left Craniotomy for subdural Hematoma with Dr. [**First Name (STitle) **] + + +History of Present Illness: +This is a 69 year old male who has been on Coumadin for a +history of multiple DVTs and a PE. He had complained of a +headache for several days and had multiple episodes of vomiting. +His son found him confused after family members reported a +stuporous ""drunken"" state. He was brought to the OSH. He +reportedly wasmoving all extremities and was able to answer some +questions. +His head CT revealed a large left SDH. He was given 10 mg SC of +vitamin K and FFP as well as a dilantin load. He was transferred +to [**Hospital1 18**] for a neurosurgical evaluation. + +Upon arrival to [**Hospital1 18**], he was still moving spontaneously +but unable to answer questions per the ER. He was given +profiline +and a second dose of FFP. + + +Past Medical History: +varicose vein stripping +DVT L superfical femoral +L4-5, L5-S1 stenosis +HTN +hyperlipidemia +PE +IVC filter +hip replacement + +Social History: +warehouse worker forced to quit 1 [**1-13**] yrs ago due to L hip pain. +no tobacco, no ETOH + + +Family History: +NC + +Physical Exam: +On admission: +T:98.3 BP:147/89 HR:89 RR:17 O2Sats:98% 4L NC +Gen: Lethargic, agitated +HEENT: Pupils: PERRL EOMs-unable to test +Neck: Supple. +Lungs: CTA bilaterally. +Cardiac: RRR. S1/S2. +Abd: Obese, Soft, NT, BS+ +Extrem: Warm and well-perfused. +Neuro: +Mental status: Lethargic, follows some commands. + +Cranial Nerves: +I: Not tested +II: Pupils equally round and reactive to light, 3 to 2 mm +bilaterally. Visual fields are full to confrontation. +III, IV, VI: unable to test +V, VII: Facial strength and sensation intact and symmetric. +VIII: Hearing intact to voice. +IX-XII: Tongue midline without fasciculations. + +Motor: Normal bulk and tone bilaterally. No abnormal movements, +tremors. Moving left side spontaneously. Moving RUE +spontaneously +but less than left. Briskly withdraws RLE to minimal noxious +stimuli. Unable to assess pronator drift. + +Sensation: Appears intact to light touch bilaterally and patient +opens eyes and says ""Ai"" to noxious stimuli. + +On Discharge: +A&Ox3 +PERRL 3-2mm bilaterally +EOMs: intact +Face symmetrical +Tongue midline +Motor: D B T IP Q H [**Last Name (un) **] AT [**Last Name (un) 938**] + R 5 5 5 5 5 5 5 5 5 + L 5 5 5 5 5 5 5 5 5 +Incision: clean, dry and intact- anterior aspect of wound has an +area of white- appears to be dressing that was stuck to +incisional glue. + +Pertinent Results: +CT Head [**2142-2-13**]: +Left subdural hematoma with a hyperdense focus in the left +frontoparietal +region consistent with acute hemorrhage. 1.4 cm rightward +subfalcine +herniation and compression of the left lateral ventricle without +ventricular entrapment. Overall, unchanged since outside +hospital study performed two hours ago. + +CT Head [**2142-2-14**]: +Newly apparent 5-mm in transverse dimension posteriorly centered + +right subdural hemorrhage. The patient is status post left +craniotomy with +interval evacuation of previously noted left subdural +hemorrhage. Improvement in mass effect with now 4 mm rightward +midline shift decreased from 9 using comparable measurements. +Improvement in compression of the left lateral ventricle. + +LENIS [**2142-2-15**]: +1. Incomplete compressibility of the left mid-to-lower +superficial femoral +vein which may represent partially occlusive or chronic DVT. +2. No evidence of right lower extremity DVT. + +CT Head [**2142-2-19**]: +Stable CT scan + + +Brief Hospital Course: +Mr. [**Known lastname 1794**] was admitted to [**Hospital1 18**] under the CAre of Dr [**First Name (STitle) **]. He +was taken to the OR on the evening of [**2142-2-13**] for Left craniotomy +for SDH evacuation. He was left intubated and transported to the +ICU. He was extubated aorund noon on [**2142-2-14**]. He was MAE with +right sided weakness but not following commands. HE became +febrile to 101.8 early am on [**2142-2-15**]. Sputum cultures were +positive for Gram + cocci in pairs. LENS showed a Left +superficial femoral DVT that was either chronic or a new +partially occlusive DVT. His PCP [**Last Name (NamePattern4) **].[**Last Name (STitle) 1057**] was contact[**Name (NI) **] at his +new office [**Telephone/Fax (1) 14331**]. His office had records dating from +[**2139**]. The patient has been on Coumdain since then without a new +diagnosis of DVT. Therefore we determined that his origical DVT +was prior to [**2139**] and this finding was consistant with new L +DVT. Venodynes were removed form the LLE. Hematology was +consulted with regards to whether anticoagulation is warranted. +In the context of a recent evacuation of the SDH and the small +size of the DVT, it was felt that the patient can be initiated +on subcutaneous heparin at prophylactic dose since the patient +has an IVC filter in place. The joint decision between +neurosurgery and hematology was to initiate anti-coagulation +approxiamtely 2 weeks after the SDH evacuation. He was seen by +the Speach/Swallow service. They recommended a pureed diet. + +His neruologic status was improved on 2.4 and transfer to the +SDU was initiated. On [**2142-2-16**] he was neurologically stable in the +SDU. Levofloxacin was started in the setting of low grade fever +and sputum with gram + cocci. CT head showed a L PCA infarct. +Stroke Neurology was consulted. Work up revealed no evidence of +embolic or thrombotic lesions. The patient will f/u with the +neurology clinic for work up of hypercoagulability. + +Also on [**2142-2-16**], his foley was discontiued for a voiding trial. +His bowel regimen was increased. PT and OT were consulted. KUB +showed a decrease in air in small bowel and repeat head CT was +stable. + +Pt was cleared to go to rehab on [**2142-2-19**] + + +Medications on Admission: +Coumadin 6 mg daily +Verapamin ER 180 mg daily +Simvastatin 20 mg daily +Ibuprofen 600 mg PRN - arthritic pain +Aspirin 81 mg daily + + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H (every +6 hours) as needed for pain, temp. +2. Simvastatin 10 mg Tablet Sig: Two (2) Tablet PO DAILY +(Daily). +3. Verapamil 120 mg Tablet Sig: 0.5 Tablet PO Q8H (every 8 +hours). +4. Levetiracetam 750 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day). +5. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +6. Insulin Lispro 100 unit/mL Solution Sig: One (1) +Subcutaneous ASDIR (AS DIRECTED). +7. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +8. Metoprolol Tartrate 25 mg Tablet Sig: 0.5 Tablet PO Q6H +(every 6 hours). +9. Hydrocortisone Acetate 1 % Ointment Sig: One (1) Appl Rectal +TID (3 times a day) as needed for PRN. +10. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO BID (2 times a day). +11. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO Q6H +(every 6 hours) as needed for Constipation. +12. Magnesium Hydroxide 400 mg/5 mL Suspension Sig: Thirty (30) +ML PO Q6H (every 6 hours) as needed for Constipation. +13. Senna 8.6 mg Tablet Sig: Two (2) Tablet PO BID (2 times a +day). +14. Docusate Sodium 50 mg/5 mL Liquid Sig: One (1) PO TID (3 +times a day). +15. Polyethylene Glycol 3350 17 gram/dose Powder Sig: One (1) +PO DAILY (Daily). +16. Famotidine 20 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +17. Levofloxacin 500 mg Tablet Sig: One (1) Tablet PO Q24H +(every 24 hours) for 4 days. Tablet(s) +18. Sodium Chloride 0.9% Flush 3 mL IV Q8H:PRN line flush +Peripheral line: Flush with 3 mL Normal Saline every 8 hours and +PRN. +19. Ondansetron 4 mg IV Q8H:PRN nausea +20. Dilaudid 2 mg Tablet Sig: 1-2 Tablets PO every six (6) hours +as needed for pain. + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital **] [**Hospital **] Hospital + +Discharge Diagnosis: +Left Subdural Hematoma +Left Superficial Femeral Deep Vein Thrombosis +Left PCA infarct + + +Discharge Condition: +Mental Status:Clear and coherent +Level of Consciousness:Alert and interactive +Activity Status:Out of Bed with assistance to chair or +wheelchair + + +Discharge Instructions: +General Instructions + +?????? Have a friend/family member check your incision daily for +signs of infection. +?????? Take your pain medicine as prescribed. +?????? Exercise should be limited to walking; no lifting, straining, +or excessive bending. +?????? You may wash your hair but do not scrub surgical wound. +Increase your intake of fluids and fiber, as narcotic pain +medicine can cause constipation. We generally recommend taking +an over the counter stool softener, such as Docusate (Colace) +while taking narcotic pain medication. +?????? Coumadin may be restarted on [**2142-2-26**] +?????? You have been prescribed an anti-seizure medicine, Keppra, +take it as prescribed. +?????? Clearance to drive and return to work will be addressed at +your post-operative office visit. +?????? You need to continue a strict bowel regimen. + +CALL YOUR SURGEON IMMEDIATELY IF YOU EXPERIENCE ANY OF THE +FOLLOWING + +?????? New onset of tremors or seizures. +?????? Any confusion or change in mental status. +?????? Any numbness, tingling, weakness in your extremities. +?????? Pain or headache that is continually increasing, or not +relieved by pain medication. +?????? Any signs of infection at the wound site: redness, swelling, +tenderness, or drainage. +?????? Fever greater than or equal to 101?????? F. + +**** SUTURES ARE DISSOLVEABLE**** Please keep dry x 7days +post-op. + +NO COUMADIN UNTIL [**2142-2-26**] + +Followup Instructions: +Follow-Up Appointment Instructions + +??????Please call ([**Telephone/Fax (1) 9403**] to schedule an appointment with Dr. +[**First Name (STitle) **], to be seen on [**2142-3-8**] (this is one week post Coumadin). +??????You will need a CT scan of the brain without contrast. + +??????You will need to follow up with Dr. [**Last Name (STitle) **] from Stroke +Neurology please call ([**Telephone/Fax (1) 7394**] for an appointment. Your +TTE was done inpatient prior to discharge. + + + +Completed by:[**2142-2-19**]",18,2142-02-13 21:28:00,2142-02-19 17:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,SUBDURAL HEMATOMA," +mr. [**known lastname 1794**] was admitted to [**hospital1 18**] under the care of dr [**first name (stitle) **]. he +was taken to the or on the evening of [**2142-2-13**] for left craniotomy +for sdh evacuation. he was left intubated and transported to the +icu. he was extubated aorund noon on [**2142-2-14**]. he was mae with +right sided weakness but not following commands. he became +febrile to 101.8 early am on [**2142-2-15**]. sputum cultures were +positive for gram + cocci in pairs. lens showed a left +superficial femoral dvt that was either chronic or a new +partially occlusive dvt. his pcp [**last name (namepattern4) **].[**last name (stitle) 1057**] was contact[**name (ni) **] at his +new office [**telephone/fax (1) 14331**]. his office had records dating from +[**2139**]. the patient has been on coumdain since then without a new +diagnosis of dvt. therefore we determined that his origical dvt +was prior to [**2139**] and this finding was consistant with new l +dvt. venodynes were removed form the lle. hematology was +consulted with regards to whether anticoagulation is warranted. +in the context of a recent evacuation of the sdh and the small +size of the dvt, it was felt that the patient can be initiated +on subcutaneous heparin at prophylactic dose since the patient +has an ivc filter in place. the joint decision between +neurosurgery and hematology was to initiate anti-coagulation +approxiamtely 2 weeks after the sdh evacuation. he was seen by +the speach/swallow service. they recommended a pureed diet. + +his neruologic status was improved on 2.4 and transfer to the +sdu was initiated. on [**2142-2-16**] he was neurologically stable in the +sdu. levofloxacin was started in the setting of low grade fever +and sputum with gram + cocci. ct head showed a l pca infarct. +stroke neurology was consulted. work up revealed no evidence of +embolic or thrombotic lesions. the patient will f/u with the +neurology clinic for work up of hypercoagulability. + +also on [**2142-2-16**], his foley was discontiued for a voiding trial. +his bowel regimen was increased. pt and ot were consulted. kub +showed a decrease in air in small bowel and repeat head ct was +stable. + +pt was cleared to go to rehab on [**2142-2-19**] + + + ","PRIMARY: [Subdural hemorrhage] +SECONDARY: [Compression of brain; Cerebral artery occlusion, unspecified with cerebral infarction; Pneumonia, organism unspecified; Hemiplegia, unspecified, affecting unspecified side; Acute venous embolism and thrombosis of deep vessels of proximal lower extremity; Long-term (current) use of anticoagulants; Personal history of venous thrombosis and embolism; Hip joint replacement; Other and unspecified hyperlipidemia; Unspecified essential hypertension; Obesity, unspecified]" +54610,122829.0,19216,2150-07-15,19215,100003.0,2150-04-21,Discharge summary,"Admission Date: [**2150-4-17**] Discharge Date: [**2150-4-21**] + +Date of Birth: [**2090-5-19**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 12174**] +Chief Complaint: +coffee ground emesis + +Major Surgical or Invasive Procedure: +EGD +Right IJ CVL + + +History of Present Illness: +Mr. [**Known lastname 52368**] is a 59M w HepC cirrhosis c/b grade I/II esophageal +varices and portal gastropathy (last EGD [**3-/2150**]), who p/w +coffee-ground emesis and melena x2 days. +. +Pt was in his USOH until about 2-3 days PTA, when he began +experiencing intermittent nausea. He had 2-3 episodes of +coffee-ground emesis and 1 episode of tarry black stool in the +morning of admission. He reports some lightheadedness which is +not new, but denies frank hematemesis, BRBPR, abdominal pain, +fever, chills, significant increases in his abdominal girth. He +denies drinking or medication non-compliance. He also reports +taking naproxen for back pain 2-3 times a day in the recent +past. +. +In the ED, his vitals were 97.4, 93/41, 69, 18, 100% on RA. He +was given 4L NS IV, protonix 40mg IV, started on an octreotide +drip. He had guaiac positive brown stool on rectal exam. He was +seen by the liver fellow in the ED who felt this was unlikely a +variceal bleed and recommended work up for infection. An NG tube +was attempted, however, patient was unable to tolerate it in the +ED. Abdominal ultrasound was done which showed a patent portal +vein, scant ascites but not enough to tap. BP dropped to 80/34, +pt transferred to MICU for hemodynamic monitoring. +. +In the MICU, pt was given 3 pRBC, Hct bumped from 21.3 to 28. +Started on norepinephrine gtt for a few hours, but BP +stabilized. On transfer to the floor, remains hemodynamically +stable. Feels good, denies tarry or bloody BMs, emesis. + +Past Medical History: +HCV Cirrhosis (tx with interferon x2 with no response) +Portal Gastropathy +Grade II Esophageal varices +HTN + +Social History: +He lives alone. He is drinking alcohol, usually one session per +week. He has four to five drinks per session. He was told to +completely abstain from alcohol, effective as of today. He +smokes about 20 cigarettes per day. + + +Family History: +NC + +Physical Exam: +ON ADMISSION: +VS: T95.9 HR 71 BP 83/36 RR 11 96% 2L NC +Gen: somnolent, oriented x 3, unable to assess for asterixis +given somnolence +HEENT: PERRLA, EOMI +Neck: supple, JVP at angle of jaw (fluid bolus running wide +open) +CV: RRR s1 s2 no appreciable murmur +Lungs: CTAB +Abd: distended, non tender, no rebound or guarding, bowel sounds +positive +Ext: 1+ pitting edema bilaterally +Skin: warm, diaphoretic, no rash or lesions noted + +Pertinent Results: +LABS ON ADMISSION: +[**2150-4-17**] 01:30PM BLOOD WBC-17.9*# RBC-2.78* Hgb-8.5* Hct-26.0* +MCV-94 MCH-30.6 MCHC-32.7 RDW-20.6* Plt Ct-186 +[**2150-4-17**] 01:30PM BLOOD Neuts-61.2 Lymphs-28.8 Monos-6.9 Eos-2.2 +Baso-0.9 +[**2150-4-17**] 02:13PM BLOOD PT-17.7* PTT-34.5 INR(PT)-1.6* +[**2150-4-17**] 01:30PM BLOOD Glucose-92 UreaN-51* Creat-1.3* Na-131* +K-5.7* Cl-104 HCO3-21* AnGap-12 +[**2150-4-17**] 01:30PM BLOOD ALT-126* AST-260* LD(LDH)-426* +AlkPhos-157* TotBili-3.3* +[**2150-4-17**] 06:41PM BLOOD Calcium-7.5* Phos-3.8 Mg-1.9 +. +LABS ON DISCHARGE: +[**2150-4-21**] 05:00AM BLOOD WBC-10.7 RBC-2.94* Hgb-9.6* Hct-27.0* +MCV-92 MCH-32.6* MCHC-35.6* RDW-21.2* Plt Ct-110* +[**2150-4-21**] 05:00AM BLOOD PT-17.4* PTT-35.6* INR(PT)-1.6* +[**2150-4-21**] 05:00AM BLOOD Glucose-84 UreaN-15 Creat-1.0 Na-132* +K-4.4 Cl-99 HCO3-25 AnGap-12 +[**2150-4-21**] 05:00AM BLOOD ALT-113* AST-210* AlkPhos-111 +TotBili-3.6* +[**2150-4-21**] 05:00AM BLOOD Calcium-8.1* Phos-3.8 Mg-1.7 +. +OTHER LABS: +[**2150-4-18**] 06:25AM BLOOD CK-MB-9 cTropnT-<0.01 +[**2150-4-17**] 06:41PM BLOOD CK-MB-11* MB Indx-4.9 cTropnT-<0.01 +[**2150-4-17**] 01:30PM BLOOD Lipase-85* +. +URINE: +[**2150-4-17**] 11:01PM URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.016 +[**2150-4-17**] 11:01PM URINE Blood-LG Nitrite-NEG Protein-NEG +Glucose-NEG Ketone-NEG Bilirub-NEG Urobiln-2* pH-5.5 Leuks-NEG +[**2150-4-17**] 11:01PM URINE RBC-63* WBC-7* Bacteri-NONE Yeast-NONE +Epi-<1 +. +MICROBIOLOGY: +Blood, urine cultures - negative +H.pylori serum antibody - negative +. +CARDIOLOGY: +. +TTE ([**4-18**]): +Conclusions +The left atrium is dilated. Left ventricular wall thicknesses +and cavity size are normal. Left ventricular systolic function +is hyperdynamic (EF>75%). Right ventricular chamber size and +free wall motion are normal. The aortic valve leaflets (3) are +mildly thickened but aortic stenosis is not present. No aortic +regurgitation is seen. The mitral valve leaflets are mildly +thickened. Mild (1+) mitral regurgitation is seen. There is +moderate pulmonary artery systolic hypertension. There is no +pericardial effusion. +IMPRESSION: Hyperdynamic LV systolic function. Mild mitral +regurgitation. Moderate pulmonary artery systolic hypertension. + +. +EKG ([**4-17**]): +Sinus rhythm +Prolonged QT interval is nonspecific but clinical correlation is +suggested +No previous tracing available for comparison + Intervals Axes +Rate PR QRS QT/QTc P QRS T +70 160 96 462/479 70 55 52 +. +GI: +EGD ([**4-20**]): +1. Varices at the lower third of the esophagus and middle third +of the esophagus. +2. Erythema and erosion in the antrum and pylorus compatible +with non-steroidal induced gastritis. +3. Bleeding from a pyloric ulcer in the pylorus compatible with +non-steroidal induced ulcer (injection, thermal therapy). +4. Normal mucosa in the duodenum. +5. Otherwise normal EGD to third part of the duodenum +. +RADIOLOGY: +. +CXR ([**4-17**]): +The prominent bulge to the right heart border could be due to +pericardial +effusion, _____ cyst, and enlarged right atrium. There is no +mediastinal +vascular engorgement to suggest cardiac tamponade. Pulmonary +vasculature is normal. The lungs are clear and there is no +pleural effusion. Overall heart size is normal. Right jugular +line ends at the junction of the +brachiocephalic veins. No pneumothorax or pleural effusion. +. +ABD U/S ([**4-17**]): +IMPRESSION: +1. No son[**Name (NI) 493**] evidence for portal venous thrombosis. Portal +vein flow is hepatopetal and wall-to-wall. +2. No significant ascites. A sliver of perihepatic ascites. +3. Persistent coarsened echotexture of the liver consistent with +known +history of cirrhosis. +4. Splenomegaly + +Brief Hospital Course: +Mr [**Known lastname 52368**] is a 59M w HCV cirrhosis w grade II esophageal varices +admitted w coffee-ground emesis and melena concerning for UGIB, +s/p MICU stay for hypotension. +. +# UGIB: Pt did not have any more bleeds while in hospital. EGD +revealed erythema and erosion in the antrum and pylorus +compatible with non-steroidal induced gastritis. Pt did remember +taking increased doses of naproxen for backache. Started on +pantoprazole 40mg PO BID for one week with repeat endoscopy +scheduled in one week ([**4-30**]). Recommended to take tylenol (max +daily dose of 2gm) for pain instead of NSAIDs. Blood pressure +meds were held at first, given MICU admission for hypotension, +but were restarted on discharge. +. +# HCV Cirrhosis: appears to be progressing to liver failure, +with elevated INR at 1.6, decreased albumin at 2.6, tbili +slightly elevated at 3.6, and chronic LE edema. Pt was continued +on prophylactic medications. +. +# FULL CODE + +Medications on Admission: +FUROSEMIDE 20mg daily +LISINOPRIL 10 mg daily +SPIRONOLACTONE 100 mg daily + +Discharge Medications: +1. Phenol 1.4 % Aerosol, Spray Sig: One (1) Spray Mucous +membrane PRN (as needed). +2. Lactulose 10 gram/15 mL Syrup Sig: Thirty (30) ML PO TID (3 +times a day). +3. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +4. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Spironolactone 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +6. Furosemide 40 mg Tablet Sig: One (1) Tablet PO once a day. +7. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every [**6-15**] +hours as needed: no more than 6 tablets of regular strength +tylenol per day. +8. Terbinafine 1 % Cream Sig: One (1) Appl Topical [**Hospital1 **] (2 times +a day) for 1 weeks. +Disp:*qs * Refills:*0* +9. Nadolol 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +10. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO twice a day for 1 weeks: +then take 1 tablet daily. +Disp:*60 Tablet, Delayed Release (E.C.)(s)* Refills:*2* +11. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +QID (4 times a day) as needed for itching. +Disp:*qs * Refills:*0* +12. Lisinopril 10 mg Tablet Sig: One (1) Tablet PO once a day. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Peptic ulcer +GI bleed + +Discharge Condition: +asymptomatic + +Discharge Instructions: +You were admitted for bleeding from an ulcer in your stomach. +This ulcer is at least partially caused by naproxen. You should +stop taking naproxen and take only tylenol for pain. You should +not take any NSAIDS for pain including ibuprofen, naproxen, +aleve, motrin, aspirin, toradol, or advil. It is okay to take +tylenol but do not take more than 4 extra strength tylenol a day +(2gram daily maximum). +. +The following medication changes were made: +Do not take naproxen +Take pantoprazole 40 mg twice daily for one week. Then take 40 +mg daily. +. +You are scheduled to get a repeat endoscopy next week. Prior to +the procedure do not have anything to drink or eat after +midnight. +. +Please return to the ER if you have any chest pain, +lightheadeness, fever, chills, bloody or black stools or any +other concerning symptoms. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Apartment Address(1) **] (ST-3) GI ROOMS Date/Time:[**2150-4-30**] 1:30 +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern1) 7290**], MD Phone:[**Telephone/Fax (1) 463**] Date/Time:[**2150-4-30**] +1:30 +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 2424**], MD Phone:[**Telephone/Fax (1) 2422**] +Date/Time:[**2150-5-7**] 11:00 + + + +Completed by:[**2150-4-24**]",85,2150-04-17 15:34:00,2150-04-21 17:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,UPPER GI BLEED," +mr [**known lastname 52368**] is a 59m w hcv cirrhosis w grade ii esophageal varices +admitted w coffee-ground emesis and melena concerning for ugib, +s/p micu stay for hypotension. +. +# ugib: pt did not have any more bleeds while in hospital. egd +revealed erythema and erosion in the antrum and pylorus +compatible with non-steroidal induced gastritis. pt did remember +taking increased doses of naproxen for backache. started on +pantoprazole 40mg po bid for one week with repeat endoscopy +scheduled in one week ([**4-30**]). recommended to take tylenol (max +daily dose of 2gm) for pain instead of nsaids. blood pressure +meds were held at first, given micu admission for hypotension, +but were restarted on discharge. +. +# hcv cirrhosis: appears to be progressing to liver failure, +with elevated inr at 1.6, decreased albumin at 2.6, tbili +slightly elevated at 3.6, and chronic le edema. pt was continued +on prophylactic medications. +. +# full code + + ","PRIMARY: [Acute gastric ulcer with hemorrhage, without mention of obstruction] +SECONDARY: [Acute posthemorrhagic anemia; Chronic hepatitis C without mention of hepatic coma; Cirrhosis of liver without mention of alcohol; Esophageal varices in diseases classified elsewhere, without mention of bleeding; Other specified disorders of stomach and duodenum; Unspecified essential hypertension; Unspecified gastritis and gastroduodenitis, without mention of hemorrhage; Edema]" +54610,147673.0,19217,2150-12-28,19216,122829.0,2150-07-15,Discharge summary,"Admission Date: [**2150-7-13**] Discharge Date: [**2150-7-15**] + +Date of Birth: [**2090-5-19**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 949**] +Chief Complaint: +Blood in rectum; Possible confusion + +Major Surgical or Invasive Procedure: +None + + +History of Present Illness: +60 yo M with Hep C cirrhosis, grade II esophageal varices, +recent admission for UGIB [**2-9**] NSAID gastritis, referred for +admission throught the ED by hepatology clinic. Pt had called in +to ask about recent medication changes and was noted by NP to +have slurred speech and tangentail thought process. Also relayed +hx of new imbalance leading to a fall during which he may have +hit his head on [**7-7**]. Per his brother (who lives in [**State **] +but speks to him by phone regularly), his speech has been off +baseline since his discharge in [**2150-4-8**]. Pt's partner who +lives in the area could not be contact[**Name (NI) **] to corroborate. Per +last liver clinic note has been off ETOH since [**Month (only) **] +(corroborated with pt) and if stays off may be candidate for +transplant list in [**2150-9-8**]. +. +In the ED, initial vs were: T=97.8 P=73 BP R O2 sat. Routine +rectal exam revealed bright red blood in rectum and Hct was 30 +which down from last measurement on [**7-7**] but not really +deviating from recent baseline. Pt did not tolerate NG tube +placement. Seen by hepatology and started on IV PPI and +octreotide drip. Hemodynamically stable throughout entire ED +course. NCHCT done to r/o bleed given hx of head injury was +unremarkable. +. +Neuro was consulted shortly after arrival to floor regarding +concern for facial droop and slurrred speech. Per their initial +eval, not concerning for acute ischemic infarct. + + +Past Medical History: +HCV Cirrhosis (tx with interferon x2 with no response) +Portal Gastropathy +Grade II Esophageal varices +HTN +Recent admission [**4-/2150**]: UGIB [**2-9**] non-steroidal induced +gastritis + + +Social History: +He lives alone. He is drinking alcohol, usually one session per +week. He has four to five drinks per session. He was told to +completely abstain from alcohol, effective as of today. He +smokes about 20 cigarettes per day. + +Family History: +NC + +Physical Exam: +General: Alert, oriented, no acute distress +HEENT: Sclera anicteric, MMM, oropharynx clear +Neck: supple, JVP not elevated, no LAD +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: Regular rate and rhythm, normal S1 + S2, no murmurs, rubs, +gallops +Abdomen: soft, non-tender, non-distended, bowel sounds present, +no rebound tenderness or guarding, no organomegaly +Ext: Warm, well perfused, 2+ pulses, no clubbing, cyanosis or +edema + + +Pertinent Results: +Admit Labs: +WBC-13.6* RBC-3.10* Hgb-10.7* Hct-30.8* MCV-100* MCH-34.6* +MCHC-34.8 RDW-20.0* Plt Ct-132* +Neuts-61 Bands-6* Lymphs-14* Monos-14* Eos-0 Baso-0 Atyps-0 +Metas-2* Myelos-2* Promyel-1* +Hypochr-NORMAL Anisocy-2+ Poiklo-1+ Macrocy-3+ Microcy-NORMAL +Polychr-OCCASIONAL Target-1+ Schisto-OCCASIONAL Tear +Dr[**Last Name (STitle) 833**] +Plt Smr-LOW Plt Ct-132* +PT-15.8* PTT-34.2 INR(PT)-1.4* +Glucose-126* UreaN-28* Creat-1.1 Na-123* K-4.8 Cl-93* HCO3-24 +AnGap-11 +Calcium-8.5 Phos-3.4 Mg-1.9 +ALT-132* AST-228* CK(CPK)-346* AlkPhos-193* TotBili-7.6* +CK-MB-11* MB Indx-3.2 cTropnT-<0.01 +Ethanol-NEG Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +URINE Color-Yellow Appear-Clear Sp [**Last Name (un) **]-1.006 Blood-NEG +Nitrite-NEG Protein-NEG Glucose-NEG Ketone-NEG Bilirub-NEG +Urobiln-NEG pH-6.5 Leuks-NEG +URINE bnzodzp-NEG barbitr-NEG opiates-NEG cocaine-NEG +amphetm-NEG mthdone-NEG + +Hapto-<20* + +On discharge: +WBC-11.2* RBC-3.23* Hgb-10.8* Hct-32.3* MCV-100* MCH-33.4* +MCHC-33.4 RDW-18.8* Plt Ct-136* +PT-15.7* PTT-33.1 INR(PT)-1.4* +Glucose-116* UreaN-26* Creat-1.1 Na-123* K-5.3* Cl-94* HCO3-22 +AnGap-12 +ALT-131* AST-239* AlkPhos-137* TotBili-8.9* + +Studies: + +CT Head Without Contrast - No acute intracranial process. + +CXR (PA/Lat) - No evidence of acute cardiopulmonary +abnormalities. Hyperinflated lungs. + +EKG: Sinus rhythm. Normal tracing. + + +Brief Hospital Course: +# Concern for GI Bleed - Considering that the patient had stable +hematocrits after his admission to the hospital and that blood +was only found in his rectum on exam, it was felt that he was +not experiencing a significant GI bleed. Nevertheless, he was +admitted to the ICU for monitoring overnight. He was kept on an +octreotide drip and an IV PPI overnight. His hematocrit +remained stable overnight and he did not have any GI bleeding +events. The following day, he was transferred to the floor. He +is scheduled for an outpatient colonoscopy with Dr. [**Last Name (STitle) **]. + +# Altered mental status - The patient presented with a history +of unstable gait, a possible facial droop, and slurred speech of +questionable chronicity. This combination, in conjunction with +normal hematocrit, was concerning for ischemic stroke. +Neurology was consulted. Neurology felt that the patient's +symptoms were possibly metabolic in nature and mentioned that +hyponatremia could contribute to falls and a change in mental +status. The patient was also started on lactulose secondary to +his having possibly mental status changes in the setting of +liver disease. Considering his alcohol history, he was also +started on thiamine and folate. + +# Hepatitis C Cirrhosis and Worsening LFTs - The most striking +change in the patient's liver function tests was the increase in +his total and direct bilirubin. Another worrisome feature was +the increase in the patient's AFP. This could be progression of +cirrhosis as he failed interferon twice. He is to follow-up with +Dr. [**Last Name (STitle) **] as an outpatient to work this up. + +# Alcohol Abuse - According to the patient and the hepatology +clinic notes, the patient has quit using alcohol. On admit, he +was started on thiamine and folate. He was also placed on the +CIWA protocol as needed, in case he had been drinking. Of note, +the patient was negative for alcohol on admission. +. +# Abnormal Differential - On his admit labs, the patient had an +abnormal differential, and he complained of a sore throat prior +to admission with thrush seen per patient. He had a repeat +differential that was also abnormal. His chest x-ray and +urinalysis were negative. He was afebrile throughout hospital +course. + +Medications on Admission: +CLOBETASOL 0.05 % Ointment twice a day +FLUOCINOLONE 0.025 % Cream +FUROSEMIDE 40 mg daily +GABAPENTIN 300 mg Capsule; [**1-10**] Capsule(s) by mouth once daily +takes prn for sleep or itch +LISINOPRIL 10 mg Tablet daily +NADOLOL 20 mg Tablet daily +PANTOPRAZOLE 40 mg daily +SPIRONOLACTONE 100 mg daily +ACETAMINOPHEN 500 mg Tablet as needed for 2-3 times daily prn + + +Discharge Medications: +1. Nadolol 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +2. Gabapentin 300 mg Capsule Sig: One (1) Capsule PO HS (at +bedtime) as needed for SLEEP/ITCH. +3. Clobetasol 0.05 % Ointment Sig: One (1) Appl Topical [**Hospital1 **] (2 +times a day). +4. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +6. Lactulose 10 gram/15 mL Syrup Sig: Sixty (60) ML PO TID (3 +times a day). +Disp:*1 bottle* Refills:*3* +7. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO once a day. +8. Rifaximin 200 mg Tablet Sig: Two (2) Tablet PO three times a +day. +Disp:*180 Tablet(s)* Refills:*2* +9. Lasix 20 mg Tablet Sig: [**1-9**] Tablet PO once a day: please hold +this medication for now. +10. Spironolactone 100 mg Tablet Sig: One (1) Tablet PO once a +day. + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +encephalopathy +hyponatremia + + +Discharge Condition: +stable + + +Discharge Instructions: +You were admitted to the hospital for confusion and slurred +speech. The neurologists saw you and thought this was not +related to your brain. You were found to have some blood in +your stool but your blood count did not significantly drop. You +will need a colonoscopy to evaluate this as an outpatient. +. +Your blood work also showed low sodium. You should restrict your +fluid intake to one liter (32 oz) daily. Do not eat or drink ice +and ice chips. Limit popsicles to [**2-10**] daily. Please hold the +lasix and Sprinonolactone until you have labs checked and +discuss this with Dr. [**Last Name (STitle) **]. You should go to the lab in the +[**Hospital Unit Name **] on [**Doctor First Name **] to have your sodium checked +on Monday. +. +The following medications were changed: +- stop lasix and spironolactone temporarily +- start taking lactulose to improve confusion +- start taking rifaxamin to improve confusion + +Please keep your appointments as listed below. + +If you experience lots of bleeding from your rectum, vomiting +blood or worsening confusion, go to the ER. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 2424**], MD Phone:[**Telephone/Fax (1) 2422**] +Date/Time:[**2150-7-28**] 8:45 +. +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 2424**], MD Phone:[**Telephone/Fax (1) 2422**] +Date/Time:[**2150-10-6**] 10:15 +Provider: [**Name10 (NameIs) **] [**Apartment Address(1) **] (ST-3) GI ROOMS Date/Time:[**2150-8-5**] 8:30 + + + +",166,2150-07-13 18:56:00,2150-07-15 17:40:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ALTERED MENTAL STATUS," +# concern for gi bleed - considering that the patient had stable +hematocrits after his admission to the hospital and that blood +was only found in his rectum on exam, it was felt that he was +not experiencing a significant gi bleed. nevertheless, he was +admitted to the icu for monitoring overnight. he was kept on an +octreotide drip and an iv ppi overnight. his hematocrit +remained stable overnight and he did not have any gi bleeding +events. the following day, he was transferred to the floor. he +is scheduled for an outpatient colonoscopy with dr. [**last name (stitle) **]. + +# altered mental status - the patient presented with a history +of unstable gait, a possible facial droop, and slurred speech of +questionable chronicity. this combination, in conjunction with +normal hematocrit, was concerning for ischemic stroke. +neurology was consulted. neurology felt that the patients +symptoms were possibly metabolic in nature and mentioned that +hyponatremia could contribute to falls and a change in mental +status. the patient was also started on lactulose secondary to +his having possibly mental status changes in the setting of +liver disease. considering his alcohol history, he was also +started on thiamine and folate. + +# hepatitis c cirrhosis and worsening lfts - the most striking +change in the patients liver function tests was the increase in +his total and direct bilirubin. another worrisome feature was +the increase in the patients afp. this could be progression of +cirrhosis as he failed interferon twice. he is to follow-up with +dr. [**last name (stitle) **] as an outpatient to work this up. + +# alcohol abuse - according to the patient and the hepatology +clinic notes, the patient has quit using alcohol. on admit, he +was started on thiamine and folate. he was also placed on the +ciwa protocol as needed, in case he had been drinking. of note, +the patient was negative for alcohol on admission. +. +# abnormal differential - on his admit labs, the patient had an +abnormal differential, and he complained of a sore throat prior +to admission with thrush seen per patient. he had a repeat +differential that was also abnormal. his chest x-ray and +urinalysis were negative. he was afebrile throughout hospital +course. + + ","PRIMARY: [Chronic hepatitis C with hepatic coma] +SECONDARY: [Hyposmolality and/or hyponatremia; Hemorrhage of rectum and anus; Portal hypertension; Esophageal varices in diseases classified elsewhere, without mention of bleeding; Alcoholic cirrhosis of liver; Other and unspecified alcohol dependence, unspecified; Anemia, unspecified; Other specified disorders of stomach and duodenum; Unspecified gastritis and gastroduodenitis, without mention of hemorrhage; Unspecified essential hypertension; Tobacco use disorder]" +61932,165934.0,15105,2159-07-20,15104,126267.0,2159-05-22,Discharge summary,"Admission Date: [**2159-5-7**] Discharge Date: [**2159-5-22**] + +Date of Birth: [**2093-11-29**] Sex: M + +Service: NEUROSURGERY + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 1835**] +Chief Complaint: +Right hand clumsiness + + +Major Surgical or Invasive Procedure: +[**5-9**]->Left Craniotomy for mass resection +[**5-14**]->Right Craniotomy for mass resection + + +History of Present Illness: +65 y/o male who has had right arm weakness/clumsiness +characterized by dropping of objects difficulty with position +sensation, went to [**Hospital6 **] on [**5-7**] when symptoms +became worse. Ct of the head showed an area of hemorrhage in the +left temp/ parietal lobe and an MRI revealed two lesions one in +the right and one in the left temp. parietal regions. He was +then transferred to [**Hospital1 18**] for definitive neurosurgical care + +Past Medical History: +Melanoma lesion on left posterior neck resected two years ago +with clear margins. +Diverticulosis +s/p partial bowel resection + +Social History: +Married, One glass of wine/day, remote smoking history 30 years +ago for 20yrs/pk/day + + +Family History: +father-leukemia +[**Name (NI) 44090**] CA + + +Physical Exam: +Exam upon admission: +T:98.6 BP: 153 /100 HR: 80 R:18 O2Sats:98% RA +Gen: WD/WN, comfortable, NAD. +HEENT: Pupils: L 7mm flicker, R 6 to 4 brisk EOMs: intact +Neck: Supple. +Abd: Soft, NT, BS+ +Extrem: Warm and well-perfused. +Neuro: +Mental status: Awake and alert, cooperative with exam, normal +affect. +Orientation: Oriented to person, place, and date. +Recall: [**3-27**] objects at 5 minutes. +Language: Speech fluent with good comprehension and repetition. +Naming intact. No dysarthria or paraphasic errors. + +Cranial Nerves: +I: Not tested +II: Pupils equally round and reactive to light, as above. Visual +fields are full to confrontation. +III, IV, VI: Extraocular movements intact bilaterally without +nystagmus. +V, VII: Facial strength and sensation intact and symmetric. +VIII: Hearing intact to voice. +IX, X: Palatal elevation symmetrical. +[**Doctor First Name 81**]: Sternocleidomastoid and trapezius normal bilaterally. +XII: Tongue midline without fasciculations. + +Motor: Normal bulk and tone bilaterally. Right hand grip +strength +4/5, finger to nose dysmetria and pronator drift. No abnormal +movements. Left arm strength full. +Sensation: Intact to light touch +Reflexes: B T Br Pa Ac +Right 2 2 2 2 2 +Left 2 2 2 2 2 + +Toes downgoing bilaterally +No clonus + +Exam on Discharge: +The patient is dysarthric. He is oriented x 3. He has a slightly +flattened left nasal labial fold. Pupils are PERRL. He has +persistant right upper extremity weakness, and left upper +extremity weakness that is steroid dose dependent. His +distal(LE) strength is full. Sensation is intact. Both wounds +are clean, dry and intact; without erythema or drainage. Sutures +have been removed. + +Pertinent Results: +Labs on Admission: +[**2159-5-7**] 12:20AM BLOOD WBC-10.3 RBC-4.61 Hgb-13.9* Hct-40.4 +MCV-88 MCH-30.2 MCHC-34.5 RDW-13.2 Plt Ct-361 +[**2159-5-7**] 12:20AM BLOOD Neuts-87.4* Lymphs-9.2* Monos-2.2 Eos-0.8 +Baso-0.4 +[**2159-5-7**] 12:20AM BLOOD PT-14.1* PTT-27.5 INR(PT)-1.2* +[**2159-5-7**] 03:30AM BLOOD Calcium-9.4 Phos-2.4* Mg-2.1 + +Labs on Discharge: +XXXXXXXXXXX + +Imaging: +CT Torso [**2159-5-7**]: +CT CHEST: The left thyroid is enlarged and heterogeneous without +focal +lesion. A 2.9 x 2.1 cm left lower lobe subpleural lung mass +(3:42) and a 5 mm right upper lobe nodule (3:40) are noted. +Calcified nodule near the right hilum (3:33) likely represents +sequela of prior granulomatous disease. There is no mediastinal +adenopathy. Several enlarged right axillary lymph nodes measure +up to 25 x 22 mm (3:22). Heart size is normal. There is no +pericardial effusion. The pulmonary arteries are patent to the +segmental level. +CT ABDOMEN: The gallbladder, spleen, adrenals, and pancreas are +unremarkable. Well-circumscribed hypodense subcentimeter liver +lesion in segment III (3:50) likely represents a cyst but is not +fully characterized. The liver is otherwise unremarkable without +evidence of intra- or extra-hepatic biliary dilatation or focal +lesion. Both kidneys demonstrate several subcentimeter well- +circumscribed lesions which likely represent cysts but are not +fully characterized. There is extensive descending and distal +transverse colon diverticulosis without evidence of +diverticulitis. The intra-abdominal loops of large and small +bowel are otherwise unremarkable without evidence of +pneumatosis, free air, or obstruction. There is no mesenteric or +retroperitoneal lymphadenopathy. +CT PELVIS: The bladder, rectum, and prostate are unremarkable. +There is +extensive sigmoid diverticulosis without evidence of +diverticulitis. +Bone windows demonstrate no lesion that is concerning for +metastasis or +infection. Mild multilevel degenerative changes are noted. +IMPRESSION: +1. Left lower lobe lung mass likely represents metastasis, +although tissue +diagnosis can be obtained if indicated. +2. Right axillary lymphadenopathy likely reflects metastatic +recurrence. +3. Heterogeneous left thyroid should be further evaluated on +thyroid +ultrasound. +4. Extensive diverticulosis without evidence of diverticulitis. + +Head CT [**5-7**]: +FINDINGS: In the right frontotemporal region, there is a 2.5 x +3.3 cm +hypodensity with fine hyperdense rim and surrounding vasogenic +edema (series 2, image 19). This is essentially identical in +size to the lesion defined on the MR (2.6 x 3.3 cm). There is +slight effacement of the subjacent body of the right lateral +ventricle but no significant shift of the midline structures. At +the left frontovertex, there is 2.2 x 3.0 cm hyperdense lesion, +with mild surrounding vasogenic edema and overlying subarachnoid +hemorrhage, similar in size to the lesion defined on the MR (2.0 +x 2.7 cm). At the posterolateral aspect of this process, there +is an ovoid isodense focus measuring 1.2 x 0.9 cm (2:24), +corresponding to the enhancing peripheral nodule on the MR. [**Name13 (STitle) **] +other foci of acute hemorrhage are seen. There is no fracture. +There is no osteolytic or- blastic lesion. Mastoid air cells and +paranasal sinuses are clear. No subcutaneous nodules are +demonstrated. +IMPRESSION: Unchanged appearance of right frontotemporal lesion +and left +frontovertex hemorrhagic lesion, likely metastases (for further +details, +please refer to the MR [**First Name (Titles) 767**] [**Hospital6 1597**]). + +MRI Head [**5-11**](post-rsxn): +FINDINGS: The patient is status post left parietal craniotomy, +in comparison with the prior study, the previously described +left frontal lobe mass lesion, has been resected. The T1 +sequence without contrast demonstrates a nodular area of +hyperintensity signal, likely consistent with blood products and +apparently unchanged after the administration of gadolinium +contrast. Restricted diffusion is noted adjacent in the +posterior margin of the surgical area, blooming artifacts and +magnetic susceptibility changes are visualized in the surgical +bed. The pattern of vasogenic edema is unchanged. The right +frontoparietal deep white matter lesion is unchanged and +demonstrates again thick rim enhancement as well as mural +enhancement as described in the prior examination. Normal flow +void signal is identified in the major vascular structures, the +orbits, the paranasal sinuses and mastoid air cells are +unremarkable. +IMPRESSION: 1. Status post left parietal craniotomy, there is a +nodular area of hyperintensity signal in the surgical bed and +posterior surgical margin, likely consistent with blood +products, however residual mass lesion is a consideration, +follow-up is recommended. +2. Similar pattern of vasogenic edema, the right frontoparietal +deep white +matter lesion is unchanged. + +Head CT [**5-14**](post-rsxn) +FINDINGS: Again noted are left parietal craniotomy changes, with +air seen +within the surgical bed, similar in appearance to prior study. +Residual +vasogenic edema within the left frontal and parietal lobes are +again noted. +Minimal focus of hemorrhage within the surgical bed is also +unchanged. In the interim, there has been interval right frontal +craniotomy, with post-surgical changes seen, with +pneumocephalus, small foci of hemorrhage. There is residual +vasogenic edema. Additionally, there is pneumocephalus overlying +the right frontal lobe, as well as small subdural collections +bilaterally. No new foci of hemorrhage are identified. +Ventricles and sulci are normal in caliber and configuration. +There is no shift of normally midline structures. Visualized +paranasal sinuses are normally aerated. +IMPRESSION: +1. Interval right frontal craniotomy, with expected +post-surgical changes +within the surgical bed, with pneumocephalus, small amount of +hemorrhage. +2. Stable post-surgical changes within the left parietal lobe, +following +surgical resection. + +Head CT [**5-16**]: +NON-CONTRAST HEAD CT: There has been no significant interval +change since one day prior. There are bilateral craniotomies +with post-surgical changes in the left parietal lobe, including +a tiny amount of pneumocephalus, residual postoperative +hemorrhage and vasogenic edema. Within the right temporal and +parietal resection bed, there is pneumocephalus, hemorrhage and +edema. Postoperative hemorrhage is stable measuring 5.7 x 4.1 +cm. There is stable minimal shift of midline structures, of +approximately 3 mm leftward shift. No new foci of hemorrhage are +identified. The visualized paranasal sinuses and mastoid air +cells are clear. +IMPRESSION: No significant change in the right temporoparietal +lobe resection bed hemorrhage and additional postoperative edema +and pneumocephalus within the left cerebral hemisphere. + +Head CT [**5-17**]: +FINDINGS: Patient is status post bilateral craniotomies. Within +the surgical bed in the right temporal and parietal lobes, there +is residual hemorrhage, pneumocephalus, and vasogenic edema. +Compared to the prior study, there has been no interval change +in size of the residual hemorrhage. Postoperative changes in the +left parietal lobe with tiny residual hemorrhage, +pneumocephalus, and vasogenic edema are also stable. There is a +minimal leftward shift of normally midline structures of +approximately 3 mm, unchanged. There are no new foci of +hemorrhage. Ventricles and sulci are normal in caliber and +configuration without evidence of hydrocephalus. Visualized +paranasal sinuses and mastoid air cells are normally aerated. +IMPRESSION: +1. No significant interval change from the prior study in the +postoperative hemorrhage within the right temporoparietal lobe +resection bed. +2. Stable post-surgical changes with the left parietal resection +bed. + +LENIS [**5-15**]: +BILATERAL LOWER EXTREMITY ULTRASOUND: Grayscale and color +Doppler imaging of the right and left common femoral, +superficial femoral and popliteal veins demonstrate normal +compressibility, augmentation, waveforms and flow. The peroneal +veins are unremarkable. +IMPRESSION: No lower extremity DVT. + +EKG [**5-7**]: +Sinus rhythm +Modest ST junctional depression is nonspecific and may be within +normal limits, but clinical correlation is suggested No previous +tracing available for comparison + Intervals Axes +Rate PR QRS QT/QTc P QRS T +89 156 98 366/416 28 -25 5 + + +Brief Hospital Course: +The patient was admitted to the neurosurgery service on [**5-7**]. On +[**5-9**] he went to the operating room for a left sided craniotomy +to resect the first of two brain lesions. Post-operatively he +was monitored in the ICU for 24hrs without incident. He was then +transferred to the neurosurgery floor for continued planning for +the resection of the right sided lesion. During his hospital +stay, neuro oncology and radiation oncology were consulted for +this patient. On 4.20, he underwent right sided craniotomy for +debulking of said lesion prior to cyberknife therapy could be +started. Post operatively, he was again transferred to the ICU +for continued monitoring. On POD#1 he was found to have new +weakness in the left upper extremity, and to be more lethargic. +A head CT was immediately done and there was new bleeding +identified in the right sided resection cavity, as well as +increased vasogenic edema. He did not worsen neurologically that +day, so head CT was again repeated on [**5-16**]. Vasogenic edema was +again noted, and lethargy persisted. It was decided to increase +the dose of his steroids from 4mg three times daily to 6mg four +times daily. + +The patient was improving neurologically and was transferred to +the stepdown unit on [**2159-5-17**]. He was evaluated by neuro-oncology +and was scheduled for a Brain [**Hospital 341**] Clinic appointment. PT and +OT evaluated the patient and recommended rehab placement. +His diet was advanced to regular and he tolerated that well. His +steroids were initially decreased to 3mg QID, but had recurrance +of left upper extremity weakness. The steroids were again +increased to 4mg QID; and to remain at this dose until WBR +therapy was initiated and could have this re-evaluated. + +On [**5-21**],he was transported to the [**Hospital1 18**] [**Hospital Ward Name **] to receive +mapping planning for WBR. He tolerated this well, and was +returned to the [**Hospital Ward Name **]. He was then discharged to an +appropriate rehab facility on [**2159-5-22**] with follow up scheduled +in the brain tumor clinic. + +Medications on Admission: +[**Hospital1 **] Benadryl prn + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed. +2. Hydromorphone 2 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed for pain. +3. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +4. Senna 8.6 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). +5. Bisacodyl 5 mg Tablet, Delayed Release (E.C.) Sig: Two (2) +Tablet, Delayed Release (E.C.) PO DAILY (Daily) as needed. +6. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO BID (2 +times a day). +7. Camphor-Menthol 0.5-0.5 % Lotion Sig: One (1) Appl Topical +TID (3 times a day) as needed. +8. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +9. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +10. Dexamethasone 4 mg Tablet Sig: One (1) Tablet PO Q6H (every +6 hours). +11. Regular Insulin Sliding Scale +Regular Insulin Sliding Scale per nursing flow sheet + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 7**] & Rehab Center - [**Hospital1 8**] + +Discharge Diagnosis: +Right fronto-temporal, and left frontovertex brain lesions + + +Discharge Condition: +Neurologically Stable + + +Discharge Instructions: +General Instructions/Information + +?????? Have a friend/family member check your incision daily for +signs of infection. +?????? Take your pain medicine as prescribed. +?????? Exercise should be limited to walking; no lifting, straining, +or excessive bending. +?????? You may shower and wash your head normally, as your sutures +have been removed prior to discharge. +?????? Increase your intake of fluids and fiber, as narcotic pain +medicine can cause constipation. We generally recommend taking +an over the counter stool softener, such as Docusate (Colace) +while taking narcotic pain medication. +?????? Unless directed by your doctor, do not take any +anti-inflammatory medicines such as Motrin, Aspirin, Advil, and +Ibuprofen etc. +?????? You have been discharged on Keppra (Levetiracetam), you will +not require blood work monitoring. +?????? You are being sent home on steroid medication, make sure you +are taking a medication to protect your stomach (Prilosec, +Protonix, or Pepcid), as these medications can cause stomach +irritation. Make sure to take your steroid medication with +meals, or a glass of milk. +?????? Clearance to drive and return to work will be addressed at +your post-operative office visit. +?????? Make sure to continue to use your incentive spirometer while +at home. +CALL YOUR SURGEON IMMEDIATELY IF YOU EXPERIENCE ANY OF THE +FOLLOWING + +?????? New onset of tremors or seizures. +?????? Any confusion or change in mental status. +?????? Any numbness, tingling, weakness in your extremities. +?????? Pain or headache that is continually increasing, or not +relieved by pain medication. +?????? Any signs of infection at the wound site: increasing redness, +increased swelling, increased tenderness, or drainage. +?????? Fever greater than or equal to 101?????? F. + + +Followup Instructions: +Follow-Up Appointment Instructions + +??????Please return to the office in [**8-3**] days (from your 2nd +surgery) for a wound check. This appointment can be made with +the Nurse Practitioner. Please make this appointment by calling +[**Telephone/Fax (1) 1669**]. If you live quite a distance from our office, +please make arrangements for the same, with your PCP. +??????You have an appointment in the Brain [**Hospital 341**] Clinic with Dr. [**Last Name (STitle) 724**] + +[**Telephone/Fax (1) 1844**]. It is on [**2159-6-4**] at 2:00 pm. The Brain [**Hospital 341**] +Clinic is located on the [**Hospital Ward Name 516**] of [**Hospital1 18**], on [**Hospital Ward Name 23**] 8. +??????You will not need an MRI of the brain as this was done during +your acute hospitalization + + + +Completed by:[**2159-5-22**]",59,2159-05-07 01:43:00,2159-05-22 14:55:00,EMERGENCY,EMERGENCY ROOM ADMIT,LONG TERM CARE HOSPITAL,HEAD MASS," +the patient was admitted to the neurosurgery service on [**5-7**]. on +[**5-9**] he went to the operating room for a left sided craniotomy +to resect the first of two brain lesions. post-operatively he +was monitored in the icu for 24hrs without incident. he was then +transferred to the neurosurgery floor for continued planning for +the resection of the right sided lesion. during his hospital +stay, neuro oncology and radiation oncology were consulted for +this patient. on 4.20, he underwent right sided craniotomy for +debulking of said lesion prior to cyberknife therapy could be +started. post operatively, he was again transferred to the icu +for continued monitoring. on pod#1 he was found to have new +weakness in the left upper extremity, and to be more lethargic. +a head ct was immediately done and there was new bleeding +identified in the right sided resection cavity, as well as +increased vasogenic edema. he did not worsen neurologically that +day, so head ct was again repeated on [**5-16**]. vasogenic edema was +again noted, and lethargy persisted. it was decided to increase +the dose of his steroids from 4mg three times daily to 6mg four +times daily. + +the patient was improving neurologically and was transferred to +the stepdown unit on [**2159-5-17**]. he was evaluated by neuro-oncology +and was scheduled for a brain [**hospital 341**] clinic appointment. pt and +ot evaluated the patient and recommended rehab placement. +his diet was advanced to regular and he tolerated that well. his +steroids were initially decreased to 3mg qid, but had recurrance +of left upper extremity weakness. the steroids were again +increased to 4mg qid; and to remain at this dose until wbr +therapy was initiated and could have this re-evaluated. + +on [**5-21**],he was transported to the [**hospital1 18**] [**hospital ward name **] to receive +mapping planning for wbr. he tolerated this well, and was +returned to the [**hospital ward name **]. he was then discharged to an +appropriate rehab facility on [**2159-5-22**] with follow up scheduled +in the brain tumor clinic. + + ","PRIMARY: [Secondary malignant neoplasm of brain and spinal cord] +SECONDARY: [Intracerebral hemorrhage; Secondary malignant neoplasm of lung; Secondary and unspecified malignant neoplasm of lymph nodes of axilla and upper limb; Iatrogenic cerebrovascular infarction or hemorrhage; Cerebral edema; Personal history of malignant melanoma of skin; Lack of coordination; Other musculoskeletal symptoms referable to limbs; Dysphagia, unspecified; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Diverticulosis of colon (without mention of hemorrhage); Personal history of tobacco use]" +65449,169230.0,9518,2193-01-21,9517,187354.0,2192-12-26,Discharge summary,"Admission Date: [**2192-12-23**] Discharge Date: [**2192-12-26**] + +Date of Birth: [**2168-10-28**] Sex: M + +Service: MEDICINE + +Allergies: +Cozaar / Spironolactone + +Attending:[**First Name3 (LF) 4765**] +Chief Complaint: +SOB/DOE + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +Mr. [**Known lastname 32362**] is a 24 year old man with a history of non-ischemic +cardiomypathy (EF 15-20%) and morbid obesity who presents with +shortness of breath, lower extremity edema and abdominal +distention for the past 2 weeks. He states that on the day of +admission ([**2191-12-24**]) he felt short of breath and a chest tightness +described as ""pulling"" sensation in the center of his chest, +worse with deep inspiration. He reports decreased expercise +tolerance and is only able to ambulate [**12-22**] a block (previously +could ambulate several blocks). He can climb 1 flight of stairs. +He denies dietary indiscretion and states he has been taking all +medications as prescribed. He has 3 pillow orthopnea which has +worsened in the past few weeks. He denies overt chest pain, PND, +diarrhea, constipation, fever, chills, night sweats, nausea, +vomiting, dysuria. ROS is positive for chronic cough x 1 year. +He was supposed to have an EP study with or without AICD +placement on [**11-20**] that was postponed to [**2193-1-2**] for symptoms +akin to a cold. (No record in chart) + +On review of systems, he denies any prior history of stroke, +TIA, deep venous thrombosis, pulmonary embolism, bleeding at the +time of surgery, myalgias, joint pains, cough, hemoptysis, black +stools or red stools. He denies recent fevers, chills or rigors. +He denies exertional buttock or calf pain. All of the other +review of systems were negative. + +Cardiac review of systems is notable for absence of chest pain, +paroxysmal nocturnal dyspnea, orthopnea, ankle edema, +palpitations, syncope or presyncope. + +In the ED, initial vitals were 99.6 63 146/95 32 95% RA. He +triggered in the ED for tachypnea with a RR of 32 and his HR was +110-120s and sinus during his ED stay. He received 1 SL NTG, ASA +325mg and Lasix 40mg IV x 1, to which he put out 850ml of urine +and reported feeling improvement in symptoms + + +Past Medical History: +1. Presumed Idiopathic dilated cardiomyopathy, EF 15-20% (echo +[**9-28**]) +- diagnosed [**11-27**] when he presented to [**Hospital1 18**] with cough, fever, +and increasing SOB. Chest CT showed bilateral lung infiltrates +and enlarged mediastinal lymph nodes consistent with multifocal +pneumonia, and echocardiography showed moderate to severe +global left ventricular hypokinesis (LVEF = 25-30 %), with +normal valve function, and no pericardial effusion. Lab work +for RSV was positive, while HIV, influenza, EBV, CMV, Lyme and +multiple blood cultures were unremarkable. Repeated echo 10 +months later confirms severely depressed and dilated LV with +LVEF of [**10-4**]%, and LVEDD of 7.8 cm +- last hospitalized [**5-29**] for CHF exacerbation, treated with IV +lasix +- evaluated [**2192-11-1**] by ED (Dr. [**Last Name (STitle) **] for ICD placement, +recommended general anesthesia for EPS and ICD placement +2. Childhood asthma +3. Morbid obesity +4. Sleep apnea - on CPAP but has not been using it +5. Moderate, Worsening pulmonary hypertension (46 mmHg [**9-28**]) +(20-28 in [**4-28**]) +6. Fatty Liver by CT. Obese and hx of EtOH. INR 1.4-1.7 since +[**5-29**]; Bili 1.7; HCV neg; HBV immune. + +Social History: +He is unmarried and lives at home with his parents. He works as +a high school wrestling coach and in security. He never smoked. +He drank ""a lot"" in college, previously quoting 6 beer/weekend +but not elaborting this time; started drinking in [**First Name5 (NamePattern1) **] [**Last Name (NamePattern1) 32363**] +high school. He has a history of cocaine use, ""a great deal"" in +sophmore year. Drinks an occasional glass of wine. + +Family History: +Father is 65 year-old and mother is 55 year-old. +Both have diabetes. He has 4 healthy older sisters. There is no +family history of SCD or cardiomyopathy. + +Physical Exam: +VS: T= 97.3 BP= 136/61 HR=114 RR= 23 O2 sat= 97% 3L +GENERAL: Obese African-American man in NAD. Oriented x3. Mood, +affect appropriate. +HEENT: NCAT. Sclera anicteric. PERRL, EOMI. Conjunctiva were +pink, no pallor or cyanosis of the oral mucosa. No xanthalesma. + +NECK: Supple without appreciable JVP, although cannot currently +assess due to body habitus. Dark Acanthosis nigricans +bilaterally +CARDIAC: PMI located in 5th intercostal space, midclavicular +line. RR, normal S1, S2. No m/r/g. No thrills, lifts. No S3 or +S4. +LUNGS: No chest wall deformities, scoliosis or kyphosis. Resp +were unlabored, no accessory muscle use. CTAB, crackles at Right +base, no wheezes or rhonchi. +ABDOMEN: Obese with diffuse anasarca and tense skin. No pain on +palpation. Positive bowel sounds. +EXTREMITIES: 3+ pitting edema to mid-abodmen. Dry skin of lower +extremities with changes of venous stasis. +SKIN: No stasis dermatitis, ulcers, scars, or xanthomas. +Skin: dry, cool. Acanthosis as above. +Neurologic: Cn 2-12 intact, full strength globally + + +Pertinent Results: +ADMISSION LABLS + WBC-12.3* RBC-5.33 Hgb-12.7* Hct-38.8* MCV-73* MCH-23.8* +MCHC-32.8 RDW-19.1* Plt Ct-284 + Glucose-136* UreaN-15 Creat-1.0 Na-136 K-4.2 Cl-102 HCO3-23 +AnGap-15 + ALT-15 AST-25 CK(CPK)-97 AlkPhos-82 TotBili-1.7* + PT-17.3* PTT-27.9 INR(PT)-1.6* + CK-MB-2 cTropnT-<0.01 proBNP-2319* + CK-MB-NotDone cTropnT-0.01 + Digoxin-0.3* +[**2192-12-24**] 03:52AM BLOOD Calcium-8.9 Phos-4.7* Mg-1.9 Iron-PND + +IRON +calTIBC-503* Ferritn-47 TRF-387* Iron-36* + +Liver +[**2192-12-23**] PT-17.3* PTT-27.9 INR(PT)-1.6* +[**2192-12-25**] PT-16.1* PTT-28.9 INR(PT)-1.4* +[**2192-12-23**] ALT-15 AST-25 CK(CPK)-97 AlkPhos-82 TotBili-1.7* +[**2192-12-26**] TotBili-1.9* DirBili-1.0* IndBili-0.9 + + +Brief Hospital Course: +Mr. [**Known lastname 32362**] is a 24 year old man with a history of non-ischemic +cardiomyopathy, NYH Class II CHF, EF 15-20% who presents with +DOE/SOB over one month, acutely over one week. He was treated +for acute on chronic CHF exacerbation. He was diuresed with IV +and then PO lasix, achieving a net negative balance of ~ 7 +litres. He was discharged to optimize his fluid status prior to +an AICD placement + +By Problem +1. Acute on Chronic CHF Exacerbation: Underlying etiology for +patient's chronic heart failure was presumed to be viral in +origin, could also be related to cocaine use in years prior to +diagnosis or alcohol abuse. All lab testing negative except for +RSV, including HIV, EBV, CMV, Lyme, RPR. Current exacerbation +likely due to poor dietary compliance as patient does not weigh +himself daily and could easily become overloaded particularly in +the context of the Holidays. He denied any medication +noncompliance. The patient was aggressively diuresed with iV +furosemide and by time of discharge he was 7 litres net negative +and sent home on 40 mg of PO furosemide [**Hospital1 **]. + +2. Tachycardia: The patient had CHF with rates around 100-130 at +presentation. This appears to be a chronic problem per previous +notes. This improved somewhat with diuresis and improvement of +his respiratory status. Doses of metoprolol were increased over +hospitalization without change in heart rate (100-120 on +telemetry). The patient should have an AICD for purposes of +primary prevention given his low EF. Plans are underway to +finish this as an outpatient. He was discharged on 100 mg +Toprol XL [**Hospital1 **] + +3. Iron Deficiency Anemia: The patient continued to be +microcytic with indices suggestive of iron deficiency. He is +also hemoglobin AC which could explain some microcytosis. No +signs of active bleeding and previous CT [**Last Name (un) **] was negative. He +was discharged on iron TID with ascorbic acid for absorption and +senna/colace for constipation + +4: Hyperbilirubinemia/ Liver Dysfunction: Patient had a slightly +elevated INR and bilirubin at presentation with normal +transaminases. Both of these parameters were slightly above his +previous values though he doe have a known element of +non-alcoholic steatohepatitis (defined by ALT/AST and US/CT +evidence of fatty infiltration). Given his two presumptive +diagnoses (NAFLD/NASH and Congestive Hepatolpathy) he is at +increased risk of fibrosis. His negative transaminases and +elevated bilirubin (half direct, half indirect) were likely in +the setting of hepatic congestion and decreased cardiac output +during his heart failure exacerbation. His bilirubin was +elevated at the time of discharge, but this would not be +expected to fall quickly. It ought to be followed. + +5. Pulmonary Hypertension: The patient was mildly hypoxic at +presentation presumably due to exacerbation of his CHF. With +diuresis this improved. ULtimately, plan is for outpatient +right heart cath. The patient was also encouraged to use his +CPAP at home and continue the diuresis begun in house. + +6. Leukocytosis: The patient had a mild leukocytosis that was +trending down at the time of discharge. He had no fevers or +signs of acute infection. + +[**Telephone/Fax (3) 32364**] +TO BE FOLLOWED IMMEDIATELY +1) Needs BMP to evaluate response to Lasix 40 mg [**Hospital1 **] +2) Needs Weight Check, was 192 Kg standing on scale at d/c +EVENTUALLY +3) CBC, iron studies to follow progress on iron repletion +4) Ultimately, follow bilirubin, INR, assess liver status +[**Telephone/Fax (3) **] + +Medications on Admission: +Diovan 40mg PO qday +Acetaminophen + Codeine 300mg/30mg PO q4H PRN cough +ASA 325mg PO qday +Furosemide 20mg PO BID - of note, pt is not sure if he takes +20mg or 40mg [**Hospital1 **] +Digoxin 250mcg PO qday +Metoprolol Succinate ER 75mg PO BID - pt is not sure of dose +(this is per Dr.[**Name (NI) 8996**] last note) + + +Discharge Medications: +1. Valsartan 40 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +2. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +3. Digoxin 250 mcg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +4. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO TID (3 times a day). +Disp:*90 Tablet(s)* Refills:*2* +5. Ascorbic Acid 250 mg Tablet, Chewable Sig: One (1) Tablet, +Chewable PO three times a day. +Disp:*90 Tablet, Chewable(s)* Refills:*2* +6. Furosemide 40 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +Disp:*60 Tablet(s)* Refills:*2* +7. Toprol XL 100 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO twice a day: Take one pill in +the morning and one at night. +Disp:*60 Tablet Sustained Release 24 hr(s)* Refills:*2* +8. Colace 100 mg Capsule Sig: One (1) Capsule PO twice a day: +for constipation. +Disp:*60 Capsule(s)* Refills:*2* +9. Senna 8.6 mg Capsule Sig: One (1) Capsule PO once a day as +needed for constipation. +Disp:*30 Capsule(s)* Refills:*2* +10. Outpatient Lab Work +Check Na, K, BUN, Cr on Monday [**2192-12-31**] + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Acute exacerbation of chronic systolic congestive heart failure +Iron Deficiency Anemia +Morbid obesity + + +Discharge Condition: +Good, not hypoxic on room air +Ambulating without assistance +Alert and Oriented *3 + +Discharge Instructions: +Mr [**Known lastname 32362**], it was pleasure to participate in your care. You were +admitted because you had increased swelling in your legs and +difficulty breathing. This was due to an exacerbation of your +heart failure. The reasons for this exacerbation are unclear +though it may have been partially driven by more salty food over +the Holidays or more subtle diet changes. In the hospital you +received IV diuretics to help remove this fluid. You lost more +than 7 litres of fluid by the time you were discharged. This is +more than 15 pounds! It is crucial that you continue this +progress at home by being very careful with diet, fluid intake +and medication use. + +Your medications have been changed. You have been started on +iron supplementation as your low iron seems to be contributing +to your persistently low blood counts. Take your iron pills with +vitamin c or fruit juice. If you get constipated on iron, you +can take Colace twice daily or Senna; these are medications that +you can get at the pharmacy. Please continue to take your other +medications as previously described. + +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight goes up more +than 3 lbs. + +MEDICATIONS +1) LASIX/FUROSEMIDE - Take 40mg tablets in the morning when you +wake and again at 4pm, or a few hours before you go to sleep. +You must take it twice daily. Your cardiologist may change this +dose. You must follow up with your PCP for [**Name Initial (PRE) **] lab test while on +this dose +2) Toprol XL - 100 mg, twice daily - this is a new dose of your +heart rate medication. TAKE THIS MEDICATION TONIGHT. +3) Aspirin 325 mg, this is to prevent a clot in your heart +4) Iron, Vitamin C - you are very low on iron and vitamin c aids +in absorption +5) Colace and Senna - medications for constipation, if that +becomes an issue + + +Followup Instructions: +You need to have your labs checked at your PCP office +We have scheduled an appointment for monday +[**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **], MD, MPH[**MD Number(3) 708**]:[**Telephone/Fax (1) 7976**] Date/Time:[**2192-12-31**] +12:30 + +You have a pre-op evaluation on the [**1-2**]. +Provider: [**Name10 (NameIs) **] RM 1 [**Name10 (NameIs) **]-PREADMISSION TESTING Date/Time:[**2193-1-2**] +9:30 +Provider: [**First Name11 (Name Pattern1) **] [**Last Name (NamePattern4) **], M.D. Phone:[**Telephone/Fax (1) 62**] +Date/Time:[**2193-1-10**] 11:20 + + +Completed by:[**2192-12-26**]",26,2192-12-23 23:09:00,2192-12-26 13:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,CONGESTIVE HEART FAILURE," +mr. [**known lastname 32362**] is a 24 year old man with a history of non-ischemic +cardiomyopathy, nyh class ii chf, ef 15-20% who presents with +doe/sob over one month, acutely over one week. he was treated +for acute on chronic chf exacerbation. he was diuresed with iv +and then po lasix, achieving a net negative balance of ~ 7 +litres. he was discharged to optimize his fluid status prior to +an aicd placement + +by problem +1. acute on chronic chf exacerbation: underlying etiology for +patients chronic heart failure was presumed to be viral in +origin, could also be related to cocaine use in years prior to +diagnosis or alcohol abuse. all lab testing negative except for +rsv, including hiv, ebv, cmv, lyme, rpr. current exacerbation +likely due to poor dietary compliance as patient does not weigh +himself daily and could easily become overloaded particularly in +the context of the holidays. he denied any medication +noncompliance. the patient was aggressively diuresed with iv +furosemide and by time of discharge he was 7 litres net negative +and sent home on 40 mg of po furosemide [**hospital1 **]. + +2. tachycardia: the patient had chf with rates around 100-130 at +presentation. this appears to be a chronic problem per previous +notes. this improved somewhat with diuresis and improvement of +his respiratory status. doses of metoprolol were increased over +hospitalization without change in heart rate (100-120 on +telemetry). the patient should have an aicd for purposes of +primary prevention given his low ef. plans are underway to +finish this as an outpatient. he was discharged on 100 mg +toprol xl [**hospital1 **] + +3. iron deficiency anemia: the patient continued to be +microcytic with indices suggestive of iron deficiency. he is +also hemoglobin ac which could explain some microcytosis. no +signs of active bleeding and previous ct [**last name (un) **] was negative. he +was discharged on iron tid with ascorbic acid for absorption and +senna/colace for constipation + +4: hyperbilirubinemia/ liver dysfunction: patient had a slightly +elevated inr and bilirubin at presentation with normal +transaminases. both of these parameters were slightly above his +previous values though he doe have a known element of +non-alcoholic steatohepatitis (defined by alt/ast and us/ct +evidence of fatty infiltration). given his two presumptive +diagnoses (nafld/nash and congestive hepatolpathy) he is at +increased risk of fibrosis. his negative transaminases and +elevated bilirubin (half direct, half indirect) were likely in +the setting of hepatic congestion and decreased cardiac output +during his heart failure exacerbation. his bilirubin was +elevated at the time of discharge, but this would not be +expected to fall quickly. it ought to be followed. + +5. pulmonary hypertension: the patient was mildly hypoxic at +presentation presumably due to exacerbation of his chf. with +diuresis this improved. ultimately, plan is for outpatient +right heart cath. the patient was also encouraged to use his +cpap at home and continue the diuresis begun in house. + +6. leukocytosis: the patient had a mild leukocytosis that was +trending down at the time of discharge. he had no fevers or +signs of acute infection. + +[**telephone/fax (3) 32364**] +to be followed immediately +1) needs bmp to evaluate response to lasix 40 mg [**hospital1 **] +2) needs weight check, was 192 kg standing on scale at d/c +eventually +3) cbc, iron studies to follow progress on iron repletion +4) ultimately, follow bilirubin, inr, assess liver status +[**telephone/fax (3) **] + + ","PRIMARY: [Acute on chronic systolic heart failure] +SECONDARY: [Other primary cardiomyopathies; Jaundice, unspecified, not of newborn; Congestive heart failure, unspecified; Other chronic pulmonary heart diseases; Unspecified sleep apnea; Tachycardia, unspecified; Iron deficiency anemia, unspecified; Morbid obesity; Other chronic nonalcoholic liver disease; Unspecified disorder of liver; Leukocytosis, unspecified]" +66256,187869.0,13112,2169-12-02,13111,166051.0,2169-11-28,Discharge summary,"Admission Date: [**2169-11-23**] Discharge Date: [**2169-11-28**] + +Date of Birth: [**2105-9-19**] Sex: F + +Service: CARDIOTHORACIC + +Allergies: +Aspirin / Ciprofloxacin / Procardia / Niacin / Biaxin / Niaspan +/ Ibuprofen / Crestor / Quinolones / Neosporin / Adhesive Tape + +Attending:[**First Name3 (LF) 3948**] +Chief Complaint: +Cough s/p bronchoscopy + +Major Surgical or Invasive Procedure: +[**2169-11-24**] : Rigid bronchoscopy with black Dumon bronchoscope. +Cryotherapy for debridement of granulation tissue, distal left +main-stem. Balloon dilatation to 10 mm, distal left main-stem. +Mechanical debridement of granulation tissue, left main-stem. +[**2169-11-24**]: Flexible bronchoscopy +[**2169-11-23**]: Rigid bronchoscopy. Foreign body removal (Y-stent). + + +History of Present Illness: +64F with PMH of morbid obesity, OSA, severe COPD, and TBM s/p +placement of Y-stent on [**2169-11-6**], who presented today for +scheduled removal of her Y-stent. She states that since having +the stent in place she has suffered from increased shortness of +breath and coughing, with increased sputum and mucus production. +The procedure itself was uncomplicated, but in the PACU she had +nearly 2 hours of prolonged coughing which developed into +pleuritic CP. She received albuterol nebs, lidocaine nebs, IV +codeine, and 125mg IV solumedrol. A CXR revealed diffuse left +lung collapse from mucus plugging and probable aspiration. She +was placed on CPAP in the PACU with some improvement in +respiratory stauts. ABG was 7.41/47/65/31. EKG was not +concerning for ischemia. Cardiac enzymes were negative. The +decision was made to to perform bronchoscopy at that time, but +to admit to MICU for repsiraotry monitoring and possible bronch +in AM if plug had not cleared by then. +. +Currently she endorses shortness of breath above her baseline. +She has diffuse pleuritic chest pain that is non-radiating. She +occasionally has spasms of uncontrollable coughing. + + +Past Medical History: +1. Obesity. +2. History of pericarditis/tamponade secondary to polyserositis. + +She has been on steroids for this for the past 17 years. +3. History of pleural effusion. +4. Sarcoidosis. +5. GERD. +6. History of lung nodule status post thoracotomy with left +lower lobe wedge resection and ([**Hospital1 2025**] [**2160**]). +7. Asthma. +8. Hiatal hernia. +9. OSA on nocturnal CPAP (plus 12) +10. Hypertension. +11. Lactose intolerance. +12. Tracheobronchomalacia + + +Social History: +The patient is divorced. She lives alone in [**Location (un) **], +[**State 350**]. She has one son who lives close by. She has been +on disability since [**2149**]. Prior to that, she worked as a +financial analyst. She has a rare glass of wine. She quit +smoking in [**2160**]. Prior to that she smoked a pack a day for 40 +years. She has never used any illicit drugs. She denies asbestos +exposure and reports no known TB exposures. She had a negative +PPD test last year prior to starting Enbrel therapy. + +Family History: +There is no family history of lung disease or sarcoid. Her +mother died secondary to rectal cancer 82 years old. Notably she +did have lupus. Her father died secondary to an MI at 72 years +old. Her son is healthy. + +Physical Exam: +VS: 99.6 94 113/51 24 90% 2L NC +Gen: obese middle aged female, frequently coughing, but not in +acute resp distress, speaking in full sentences +HEENT: NC/AT, MMM +Neck: obese +Cor: RRR, 2/6 systolic murmur at LSB +Resp: Scattered wheezes bilateral +Abd: obese, s/nt/nd +BS +Ext: WWP. 2+ b/l pitting edema to knee. + digital clubbing + + +Pertinent Results: +[**2169-11-26**] WBC-17.5* RBC-4.55 Hgb-12.1 Hct-35.6* Plt Ct-755* +[**2169-11-25**] WBC-20.0* RBC-4.08* Hgb-10.7* Hct-31.9* Plt Ct-684* +[**2169-11-24**] WBC-15.7* RBC-3.93* Hgb-10.6* Hct-30.3* Plt Ct-603* +[**2169-11-23**] WBC-19.6*# RBC-4.12* Hgb-10.9* Hct-32.0* Plt Ct-624* +[**2169-11-23**] Neuts-91.9* Lymphs-6.2* Monos-1.4* Eos-0.5 Baso-0.1 +[**2169-11-27**] Glucose-80 UreaN-25* Creat-0.8 Na-137 K-4.1 Cl-97 +HCO3-33* +[**2169-11-27**] 02:35AM BLOOD K-4.0 +[**2169-11-25**] Glucose-129* UreaN-21* Creat-0.6 Na-139 K-3.8 Cl-96 +HCO3-32 +[**2169-11-23**] Glucose-126* UreaN-8 Na-136 K-4.1 Cl-94* HCO3-31 +[**2169-11-26**] CK(CPK)-36 [**2169-11-24**] CK(CPK)-29 [**2169-11-23**] CK(CPK)-40 +[**2169-11-27**] BLOOD cTropnT-<0.01 [**2169-11-26**] CK-MB-NotDone +cTropnT-<0.01 +[**2169-11-27**] BLOOD Calcium-9.2 Phos-3.9 Mg-2.0 + +CXR: +[**2169-11-24**] In comparison with study of [**11-23**], there has been +substantial +re-expansion of the left lung, presumably from expectoration of +a mucus plug. Atelectatic changes persist at the left base and +there is continued elevation of the left hemidiaphragmatic +contour. + +[**2169-11-23**] In comparison with the study of [**11-17**], there has been +substantial volume loss in the left lung with opacification of +most of the left hemithorax following stent removal. Some patchy +quality of the opacification raises the possibility of +supervening aspiration or hemorrhage from recent bronchoscopy. + +Chest CT: [**2169-11-27**] +1. Negative examination for pulmonary embolism. +2. Long-term stability of noncalcified pulmonary nodules, +consistent with a benign etiology. +3. Stable appearance of the left lower lobe post-surgical +changes with +scarring. +4. Coronary calcifications. +5. Mucoid impactation in bronchi of left lower lobe. + + + +Brief Hospital Course: +64F with OSA, severe COPD, and TBP s/p removal of Y-stent [**11-23**] +who is admitted to the MICU post-procedurally with left lung +collapse and evidence of mucus plugging and aspiration and +respiratory failure. She was placed on CPAP with aggressive +pulmonary toileting, chest PT and mucolytics. Intravenous +steroids were started for COPD excerbation. Cardiac enzymes +were negative. On [**2168-11-23**] she had Flexible bronchoscopy which +showed granulation tissue distal to LMS occluding 75% of lunar. +Distal airway was patent. She then procedued to the operating +room for Rigid bronchoscopy, Cryotherapy for debridement of +granulation tissue, distal left main-stem. Balloon dilatation to +10 mm, distal left main-stem. Mechanical debridement of +granulation tissue, left main-stem. She tolerated the procedure +her saturations were monitored in the ICU prior to transfer to +the floor. The post procedure chest film showed some residual +atelectasis and possibly effusion at the left base with +elevation of the left hemidiaphragmatic contour, no recurrence +of the substantial volume loss seen previously and no evidence +of pneumothorax. Her oxygenation improved Sats were 91% on 2L +nasal cannula. She transferred to the floor on a steroid taper, +home CPAP settings, aggressive pulmonary toileting and chest PT. + On [**2169-11-25**] her pain was managed with PO pain medicaiton, the +foley was removed and she voided. Her diet was advanced and she +ambulated in the halls. On [**2169-11-26**] she had an episode of atrial +fibrillation in the 150's. She was given IV lopressor with +spontaneous conversion to sinus rhythm. She was started on a +standing dose of low dose beta-blocker, her lytes were repleted. + On [**2169-11-27**] Chest CT was negative for pulmonary embolism. On +[**2169-11-28**] her respiratory status was at baseline, she continued on +a steroid taper, and was discharged to home with VNA. She will +follow-up as an outpatient. + + +Medications on Admission: +# Micardis/HCTZ 40/12.5 one tablet daily +# Nexium 40 mg t.i.d. +# Flexeril 10 mg b.i.d. +# Medrol 4 mg daily, +# Zyrtec 10 mg daily +# Singulair 10 mg daily +# cyproheptadine 4 mg b.i.d. +# Lasix 20 mg daily p.r.n. edema +# Enbrel injections 50 mg every week (has not taken in the past +two weeks) +# Advair 250/50 one puff twice daily +# Rhinocort 32 mcg two sprays per nostril daily +# vitamin E +# calcium +# vitamin C +# vitamin B12 +# multivitamin +# vitamin D +# Imodium p.r.n. +# Benadryl p.r.n +# Tylenol p.r.n. + + +Discharge Medications: +1. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +2. Montelukast 10 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Benzonatate 100 mg Capsule Sig: One (1) Capsule PO TID (3 +times a day). +4. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Calcium Carbonate 500 mg Tablet, Chewable Sig: Two (2) +Tablet, Chewable PO BID (2 times a day). +6. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +7. Fluticasone-Salmeterol 250-50 mcg/Dose Disk with Device Sig: +One (1) Disk with Device Inhalation [**Hospital1 **] (2 times a day). +8. Cyclobenzaprine 10 mg Tablet Sig: One (1) Tablet PO BID (2 +times a day) as needed. +9. Fluticasone 50 mcg/Actuation Spray, Suspension Sig: Two (2) +Spray Nasal DAILY (Daily). +10. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID +(2 times a day) as needed. +11. Oxycodone 5 mg Tablet Sig: 1-2 Tablets PO Q4H (every 4 +hours) as needed. +Disp:*50 Tablet(s)* Refills:*0* +12. Prednisone 10 mg Tablet Sig: Four (4) Tablet PO once a day +for 2 days. +Disp:*25 Tablet(s)* Refills:*0* +13. Prednisone 10 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily) for 3 days. +14. Prednisone 10 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily) +for 3 days: then 1 x days, then [**11-17**] tablet (5mg) x 3 days. +15. Saline Solution Sig: Three (3) ML Miscellaneous three +times a day: Nebulizers . +Disp:*300 * Refills:*2* +16. Micardis HCT 40-12.5 mg Tablet Sig: One (1) Tablet PO once a +day. +17. Nexium 40 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO three times a day. +18. Zyrtec 10 mg Tablet Sig: One (1) Tablet PO once a day. +19. Cyproheptadine 4 mg Tablet Sig: One (1) Tablet PO twice a +day. +20. Lasix 20 mg Tablet Sig: One (1) Tablet PO once a day as +needed. +21. Toprol XL 25 mg Tablet Sustained Release 24 hr Sig: 0.5 +Tablet Sustained Release 24 hr PO once a day. +Disp:*15 Tablet Sustained Release 24 hr(s)* Refills:*2* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital6 486**] + +Discharge Diagnosis: +Obesity. +History of pericarditis/tamponade secondary to polyserositis, +steroids x 17 yrs +History of pleural effusion. +Sarcoidosis. +GERD. +History of lung nodule status post thoracotomy with left lower +lobe wedge resection and ([**Hospital1 2025**] [**2160**]). +Asthma. +Hiatal hernia. +OSA on nocturnal CPAP (plus 12) +Hypertension. +Lactose intolerance. + + +Discharge Condition: +stable + + +Discharge Instructions: +Call Dr.[**Name (NI) 14679**] office [**Telephone/Fax (1) 7769**] if develops: +-Fever > 101 or chills +-Increased shortness of breath, cough or sputum production +Prednisone taper 40 x 2 days, 30 x 3 days, 20 x 3 days, 10 x 3 +days then 5 mg day. Please contact your rheumatologist +regarding your medrol 4 mg daily. (when to start) + +Followup Instructions: +Follow-up with Dr. [**Last Name (STitle) **] [**12-12**] @10:00am in the [**Hospital Ward Name 121**] +Building [**Hospital1 **] I Chest Disease Center, [**Location (un) **] +Follow-up with Dr. [**Last Name (STitle) **] [**12-12**] at 10:30 am Chest Disease Center +Please follow-up with your rheumatologist regarding steroids + + + +Completed by:[**2169-11-29**]",4,2169-11-23 21:13:00,2169-11-28 13:35:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOME HEALTH CARE,TRACHEAL BRONCHOMALASIA," +64f with osa, severe copd, and tbp s/p removal of y-stent [**11-23**] +who is admitted to the micu post-procedurally with left lung +collapse and evidence of mucus plugging and aspiration and +respiratory failure. she was placed on cpap with aggressive +pulmonary toileting, chest pt and mucolytics. intravenous +steroids were started for copd excerbation. cardiac enzymes +were negative. on [**2168-11-23**] she had flexible bronchoscopy which +showed granulation tissue distal to lms occluding 75% of lunar. +distal airway was patent. she then procedued to the operating +room for rigid bronchoscopy, cryotherapy for debridement of +granulation tissue, distal left main-stem. balloon dilatation to +10 mm, distal left main-stem. mechanical debridement of +granulation tissue, left main-stem. she tolerated the procedure +her saturations were monitored in the icu prior to transfer to +the floor. the post procedure chest film showed some residual +atelectasis and possibly effusion at the left base with +elevation of the left hemidiaphragmatic contour, no recurrence +of the substantial volume loss seen previously and no evidence +of pneumothorax. her oxygenation improved sats were 91% on 2l +nasal cannula. she transferred to the floor on a steroid taper, +home cpap settings, aggressive pulmonary toileting and chest pt. + on [**2169-11-25**] her pain was managed with po pain medicaiton, the +foley was removed and she voided. her diet was advanced and she +ambulated in the halls. on [**2169-11-26**] she had an episode of atrial +fibrillation in the 150s. she was given iv lopressor with +spontaneous conversion to sinus rhythm. she was started on a +standing dose of low dose beta-blocker, her lytes were repleted. + on [**2169-11-27**] chest ct was negative for pulmonary embolism. on +[**2169-11-28**] her respiratory status was at baseline, she continued on +a steroid taper, and was discharged to home with vna. she will +follow-up as an outpatient. + + + ","PRIMARY: [] +SECONDARY: [Chronic obstructive asthma with (acute) exacerbation; Pneumonitis due to inhalation of food or vomitus; Pulmonary collapse; Other specified forms of effusion, except tuberculous; Other diseases of trachea and bronchus; Other chest pain; Atrial fibrillation; Sarcoidosis; Lung involvement in other diseases classified elsewhere; Obstructive sleep apnea (adult)(pediatric); Other chronic pain; Morbid obesity; Unspecified essential hypertension; Esophageal reflux; Diaphragmatic hernia without mention of obstruction or gangrene; Long-term (current) use of steroids; Personal history of tobacco use; Other artificial opening status]" +66264,173568.0,9141,2103-01-15,9112,133806.0,2102-08-24,Discharge summary,"Admission Date: [**2102-8-14**] Discharge Date: [**2102-8-24**] + +Date of Birth: [**2061-5-10**] Sex: F + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 425**] +Chief Complaint: +nausea, dry heaving, rectal bleeding + +Major Surgical or Invasive Procedure: +cardiac catheterization + + +History of Present Illness: +Pt is a 41 yo F w/ PMHx of seizure d/o, chronic back pain, +partial gastrectomy, for obesity, who presented with vague hx of +intermittent nausea and dry heaving for 3-4 months, not +associated w/ abdominal pain, but associated with anorexia and +recently, over the past week with occasional fevers (to 102), +chills, weakness, fatigue. She admits to poor PO intake over +recent weeks, as well as occasional dizzyness when standing up +and a syncopal episode. +. +(Hx below from prior admission notes and verified during Pt +interview): +. +She has had a 25-30 pound wt loss over the past 2 months, as +well as leg and arm swelling. There was no recent travel, +unusual foods, sick contacts, or new pets. She also notes +constipation x3 mos leading to painful straining and bloody +stools, which was evaluated by flex sig at OSH showing +hemorrhoids. She was started on docusate and notes loose stools +lately associated with taking more laxatives. +. +Since admission, CT was done and showed pancolitis. GI was +consulted and did upper endoscopy which was normal. Colonoscopy +was aborted for poor prep. Two days ago, the patient developed +sharp chest pain radiating to her shoulders, no exertional +component, no change with inspiration or cough. She has had +dyspnea and chest pressure for the past week that has been +constant. Cardiac markers showed trop peak at 0.41 with CK/CKMB +normal and no EKG changes. Cards was consulted and felt this was +not an MI, maybe myocarditis, and requested TTE. This was done +today showing systolic and diastolic dysfunction (LVEF 20-30%) +with a small effusion and possible early tamponade. +. +During this admission, Pt has been persistently tachycardic +(100s to 120s) and this evening Pt was noted to have a HR +130s-140s. +. +On review of systems, s/he denies any prior history of stroke, +TIA, deep venous thrombosis, pulmonary embolism, bleeding at the +time of surgery, myalgias, joint pains, cough, hemoptysis, black +stools or red stools. S/he denies exertional buttock or calf +pain. All of the other review of systems were negative. +. +Cardiac review of systems is notable for absence of chest pain, +dyspnea on exertion, paroxysmal nocturnal dyspnea, orthopnea, +ankle edema, palpitations, syncope or presyncope. + +Past Medical History: +- Epilepsy +- Cholelithiasis +- Degenerative disc disease +- Partial gastrectomy for obesity +- Lysis of adhesion 3 weeks after gastrectomy + +Social History: +single, works at [**University/College **] as administrator. Recent breakup from +boyfriend. Lives alone. Brother is a support +-Tobacco history:None +-ETOH: social +-Illicit drugs: none + +Family History: +No family history of early MI, arrhythmia, cardiomyopathies, or +sudden cardiac death; otherwise non-contributory. + +Physical Exam: +VS: T= 97.4 BP= 104/75 HR= 104 RR= 18 O2 sat= 99% +GENERAL: NAD, Alert and Oriented x3. Flat affect. +HEENT: NCAT. Sclera anicteric. Pupils somewhat dilated but +equally round and reactive to light and accomodation, EOMI. +Conjunctiva were pink, no pallor or cyanosis of the oral mucosa. + +NECK: Supple with non elevated JVP. +CARDIAC: PMI located in 5th intercostal space, midclavicular +line. RR, normal S1, S2. No m/r/g. No thrills, lifts. No S3 or +S4. +LUNGS: No chest wall deformities, scoliosis or kyphosis. Resp +were unlabored, no accessory muscle use. CTAB, no crackles, +wheezes or rhonchi. +ABDOMEN: Soft, NTND. No HSM or tenderness. Abd aorta not +enlarged by palpation. No abdominial bruits. +EXTREMITIES: 2+ lower extremity and upper extremity edema. No +clubbing or cyanosis +SKIN: traumatic erythematous patch on R lower extremity +PULSES: +Right: Carotid 2+ Femoral 2+ Popliteal 2+ DP 2+ PT 2+ +Left: Carotid 2+ Femoral 2+ Popliteal 2+ DP 2+ PT 2+ + + +Pertinent Results: +On Admission: +[**2102-8-14**] 01:04PM WBC-18.5*# RBC-4.59 HGB-13.1 HCT-44.4# +MCV-97# MCH-28.5 MCHC-29.5*# RDW-14.0 +[**2102-8-14**] 01:04PM NEUTS-84.0* LYMPHS-11.0* MONOS-4.6 EOS-0.1 +BASOS-0.3 +[**2102-8-14**] 01:04PM PLT COUNT-577*# +[**2102-8-14**] 01:04PM ALBUMIN-2.6* +[**2102-8-14**] 01:04PM LIPASE-7 +[**2102-8-14**] 01:04PM ALT(SGPT)-45* AST(SGOT)-68* ALK PHOS-159* TOT +BILI-2.3* +[**2102-8-14**] 01:04PM GLUCOSE-114* UREA N-12 CREAT-0.9 SODIUM-139 +POTASSIUM-4.3 CHLORIDE-107 TOTAL CO2-22 ANION GAP-14 +[**2102-8-14**] 03:11PM PT-17.5* PTT-37.5* INR(PT)-1.6* +[**2102-8-15**] 12:00AM PLT COUNT-353 +[**2102-8-15**] 12:00AM WBC-7.9# RBC-3.10*# HGB-9.1*# HCT-30.0*# +MCV-97 MCH-29.2 MCHC-30.2* RDW-13.9 +[**2102-8-15**] 12:00AM CALCIUM-7.3* PHOSPHATE-2.6* MAGNESIUM-2.0 +[**2102-8-15**] 12:00AM LIPASE-7 +[**2102-8-15**] 12:00AM ALT(SGPT)-27 AST(SGOT)-24 ALK PHOS-98 +AMYLASE-15 TOT BILI-0.7 +[**2102-8-15**] 12:00AM GLUCOSE-110* UREA N-12 CREAT-0.6 SODIUM-144 +POTASSIUM-4.0 CHLORIDE-115* TOTAL CO2-22 ANION GAP-11 +TSH [**8-16**]: 3.6 +PTH [**8-16**]: 66 +B12 [**8-16**]: 1835 +HCG [**8-19**]: negative +HIV neg +HCV neg +Trig 185 +Vitamin B1 370 (normal) +prealbumin 7 + CPK ISOENZYMES CK-MB cTropnT proBNP +[**2102-8-19**] 03:09AM NotDone1 0.07*2 3928* +protein electrophoresis [**8-22**] normal +Upep [**8-21**]: 27 (normal) + +. +[**2102-8-14**] RUQ ULTRASOUND: +1. Cholelithiasis without secondary signs to suggest +cholecystitis. +2. Echogenic liver most compatible with fatty infiltration. +Please note that other forms of hepatic disease such as +cirrhosis/fibrosis are not excluded. +. +[**2102-8-15**] CT ABD/PELVIS: +1. Pancolitis as decribed above. +2. Cystic lesion in tail of pancreas, not fully evaluated on +this +examination. Would recommend MRI in 6 months for further +characterization. +3. Focal narrowing in sigmoid colon may represent focal +collapsed bowel, +however, bowel wall lesion cannot be excluded. Would recommend +imaging +correlation such as colonoscopy or barium study as available. +. +[**2102-8-16**] MRCP: +1. Severe hepatic steatosis. +2. Biliary tree shows no abnormalities. +3. Colonic wall thickening and mucosal enhancement, related to +colitis as +seen on recent CT scan. +4. Cystic, non-enhancing lesion in the tail of the pancreas, +that is most likely in keeping with a pseudocyst, however, a +side branch IPMN cannot be excluded, although less likely. A +followup MRI is suggested in six months for further evaluation. +5. Jejunal biopsy negative. +. +[**2102-8-17**] CT ABD/PELVIS: +1. No evidence of esophageal perforation. +2. Resolution of colonic wall thickening demonstrated on prior +CT. +3. Hepatic steatosis. +4. Low-attenuation lesion at the tail of the pancreas is +compatible with a cyst versus dilated side branch. It is +unchanged from prior recent MRCP and CT. As described on prior +MRCP report, followup of this with MRCP in six months is +recommended to assess for expected stability. +. +[**2102-8-18**] ECHO: +The left atrium is normal in size. Left ventricular wall +thicknesses are normal. The left ventricular cavity size is +normal. Overall left ventricular systolic function is severely +depressed (LVEF= 20-30 %). Tissue Doppler imaging suggests an +increased left ventricular filling pressure (PCWP>18mmHg). There +is no ventricular septal defect. Right ventricular chamber size +and free wall motion are normal. Right ventricular chamber size +is normal. with focal hypokinesis of the apical free wall. The +aortic valve leaflets (3) appear structurally normal with good +leaflet excursion and no aortic regurgitation. The mitral valve +appears structurally normal with trivial mitral regurgitation. +There is no mitral valve prolapse. The estimated pulmonary +artery systolic pressure is normal. There is a small to moderate +sized pericardial effusion. No right atrial or right ventricular +diastolic collapse is seen. However, the right ventricle appears +underfilled. +IMPRESSION: severe anterior and apical hypokinesis/akinesis; +small, primari8ly anterior pericardial effusion possibly with +early tamponade. +. +[**2102-8-21**] CARDIAC CATHETERIZATION: +1. Selective coronary angiography in [**Last Name (un) **] left dominant system +demonstrated no flow limiting lesions. The LMCA had minimal +plaquing in +the mid portion of the vessel. The LAD had minimal luminal +irregulairites with 15% stenosis at the origin of the vessel. +The distal +LAD wraps around the apex with diffuse plaquing in the distal +LAD. The +Cx had minimal luminal irregularities and gave off a small +caliber OM1, +an atrial branch a modest OM2, a large LPL and a moderate LPDA. +The RCA +was a small nondominant vessel that initially had catheter +induced +vasospasm that improved after intracatheter nitroglycerine. +2. Limited resting hemodynamics revealed elevated right and left +filling +pressures with an RVEDP of 17 mmHg and an LVEDP of 28 mmHg. +There was +mild pulmonary artery hypertension with a PASP of 38 mmHg. The +cardiac index was preserved at 3.3 l/min/m2. The SVR was +slightly +low at 754 dynes-sec/cm5 and the PVR was preserved at 69 +dynes-sec/cm5. +The central aortic pressure was 103/68 mmHg. There was no +transaortic +valve gradient on pullback from the LV to the aorta. +FINAL DIAGNOSIS: +1. Coronary arteries have no flow limiting lesions. +2. Mild pulmonary arterial hypertension. +3. Severe left ventricular diastolic dysfunction. +. +On Discharge: +Negative Lyme, MRSA swab, HIV, HCV and urine cx +EBV, Vitamin D [**12-25**] and CMV are still pnd +COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW +Plt Ct +[**2102-8-23**] 05:13AM 7.5 3.03* 9.1* 29.4* 97 29.9 30.8* 15.0 +431 +RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap + +[**2102-8-23**] 05:13AM 91 12 0.7 139 3.7 107 27 9 +Cosyntropin stimulation test [**8-23**]: +Cortisol prior: 6.31 +Cortisol 30 min after cosyntropin: 23.9 +Cortisol 60 min after cosyntropin: 28.5 +. + +Brief Hospital Course: +The patient is a 41 year old female with seizure disorder, +gastrectomy, degenerative disc disease who presented with vague +GI complaints, weight loss, and admitted to CCU after an episode +of chest pain and she was found to have severe systolic/dystolic +function as well as tachycardia. On [**2102-8-24**], the +patient was discharged in good condition, with stable vital +signs, with appropriate outpatient follow-up arranged. +Ms.[**Known lastname 31410**] hospital course was notable for: +. +# Hypotension: Has been intermittantly hypotensive this +admission but asymptomatic, likely [**1-2**] low EF. Hct is low and +drfting down. Random cortisol low normal and cortisone +stimulation test was normally responsive. Pt is not orthostatic +or dizzy, is able to ambulate easily and denies any symptoms. +Her Lisinopril and Metoprolol was started at a very low dose. +. +# Upper back pain: Pt has a history of lower back scoliosis, +Myofascial pain syndrome and Facet arthropathy that affects her +lower back. Her upper back pain is new. Pt feels that her pain +may be [**1-2**] bedrest, and is relieved by morphine. No radicular +symptoms. On muscle relaxer at home and chronic narcotics +(Roxicet) which pt states is ineffective. Pt reports that +clonazepam did not help as an additional muscle relaxer. She was +given a limited morphine PO prescription and instructed to +contact the pain clinic at [**Hospital1 18**] which she had used in [**2098**]. +According to the patient, they recommended surgery which she has +been reluctant to do. +. +# Acute Systolic dysfunction: Cath [**8-21**] showed no CAD. Noted +increased filling pressures and furosemide and Lasix po started. +No O2 requirement or SOB at present despite fluid overload. +Unclear etiology but fatigue in last few months may be related. +TSH neg. Multiple viral tests performed, all negative except for +EBV and CMR which are pending. Pt was discharged on Lisinopril +2.5 mg and Long acting Metoprolol with furosemide twice daily. +Instructed to weigh herself daily and follow a low sodium diet. +Pt will follow-up with Dr.[**Name (NI) 3733**] for in [**Month (only) 359**]. +. +# Nausea, weight loss: Pt had recent CT scan which showed +pancolitis, and f/u CT scan which showed interval resolution. +Also w/ cholelithiasis and steatotic hepatitis. Pt w/ fairly +substantial GI surgical hx. GI and surgery following with plan +for outpt CT colonoscopy for further evaluation. GI also +recommends outpatient MRI enterography for further evaluation. +Symptoms may represent malabsorption syndrome, such as celiac +sprue, or possibly related to surgical gastric resection. +Albumin 2.0, thought to be contributing to her peripheral edema. +EGD done, Bx showed inflmmation only. Weight loss is at least in +part r/t very decreased and erratic intake. Pt describes very +poor protein and calorie intake last 2 months. Spoke with pt's +mother who states that pt has not worked in 2 months, is +considering disability, has been increasingly isolated in her +apt with limited contact with friends. Dr. [**Name (NI) 31411**], pts +outpatient psychiatrist was informed of this information. +Worsening depression is suspected. She is tolerating PO's at +discharge. She has had extensive nutritional counseling after +her gastric bypass but would consider outpatient referral again. + +. +# Anemia: Normochromic, normocytic. On Fe supplementation as Fe +studies suggest Fe deficiency. No signs of acute bleed. Had +some rectal bleeding with stools recently, [**1-2**] hemmorhoids. +Needs repeat outpt colonoscopy. On Fe, B12 q week, folic acid +supplements. +. +# Epilepsy: No sz activity noted. Continued home meds of +levetiracetam, venlafexime, topiramate +. +# Depression: See note above about poor PO intake. Increasing +isolation, ahedonia and decreased intake all point to worsening +depression. Psych team saw pt in house but had no +recommendations as they did not have accurate information from +the patient. Outpt psychiatrist was contact[**Name (NI) **] about symptoms and +will f/u with pt. Note that pt is very reluctant to discuss some +information with her caregivers. + +Medications on Admission: +B12 injection 1,000mcg monthly +Iron 65mg daily +Zolpidem 10mg HS prn +Folic acid 1mg daily +Venlafaxine 300mg daily +Amitriptyline 25mg HS (has not taken recently) +Clonazepam 1mg daily prn anxiety +Topiramate 100mg HS +Tizanidine 8mg HS +Roxicet 5/325 q6h prn +Levetiracetam 500mg [**Hospital1 **] +Omeprazole 20mg daily (no longer taking) + +Discharge Medications: +1. Topiramate 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Levetiracetam 250 mg Tablet Sig: Two (2) Tablet PO BID (2 +times a day). +3. Ferrous Sulfate 325 mg (65 mg Iron) Tablet Sig: One (1) +Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +4. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). +Disp:*30 Tablet(s)* Refills:*2* +5. Clonazepam 1 mg Tablet Sig: One (1) Tablet PO QHS (once a day +(at bedtime)) as needed for anxiety. +6. Ascorbic Acid 500 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily): Take with iron. +7. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +8. Lisinopril 5 mg Tablet Sig: 0.5 Tablet PO DAILY (Daily). +Disp:*15 Tablet(s)* Refills:*2* +9. Furosemide 20 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +Disp:*60 Tablet(s)* Refills:*2* +10. Cyanocobalamin 1,000 mcg/mL Solution Sig: One (1) injection +Injection once a week. +11. Levetiracetam 500 mg Tablet Sig: One (1) Tablet PO twice a +day. +12. Tizanidine 4 mg Capsule Sig: Two (2) Capsule PO at bedtime. + +13. Venlafaxine 150 mg Capsule, Sust. Release 24 hr Sig: Two (2) +Capsule, Sust. Release 24 hr PO once a day. +14. Morphine 15 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +Disp:*45 Tablet(s)* Refills:*0* +15. Metoprolol Succinate 25 mg Tablet Sustained Release 24 hr +Sig: One (1) Tablet Sustained Release 24 hr PO once a day. +Disp:*30 Tablet Sustained Release 24 hr(s)* Refills:*2* + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Heart Failure: systolic dysfunction (EF 20-30%) and diastolic +dysfunction +Colitis + + +Discharge Condition: +stable + + +Discharge Instructions: +You had nausea and vomiting and were admitted to the +gastroenterology service. Multiple tests were performed, you +were found to have colitis, an irritation of the lining of your +gastrointestinal tract. This is now resolving without treatment. +Your heart rate became high and you were evaluated by the +cardiology team. Your heart function is about 50% weaker than it +should be. We have done many tests to find the cause of this +weakness but have not identified a cause as yet. You did not +have a heart attack. You need to eat a balanced diet with +adequate protein and calories every day. Because your heart is +weak, you may retain fluid in your legs, lungs or hands. Not +eating enough protein makes your swelling worse. Weigh yourself +every morning, call Dr. [**Last Name (STitle) **]""[**Doctor Last Name **] if weight > 3 lbs in 1 day or +6 pounds in 3 days. +Adhere to 2 gm sodium diet +Fluid Restriction: 1.5 liters per day or about 8 cups +. +In addition, you had a cortisol stimulation test to evaluate +your low blood pressure. Please review the results of this test +with your primary care provider at your next visit. +. + +. +Medication changes: +1. START Furosemide (Lasix) to decrease the amount of fluid in +your body +2. Lisinopril: to help your heart pump better, this will lower +your blood pressure slightly +3. Metoprolol: to slow you heart rate and help your heart work +better +4. Thiamine and Vitamin C: to correct nutritional deficencies +and help your anemia +. +Please call Dr.[**Name (NI) 3733**] if you notice any trouble breathing, +increased swelling or cough. + +Followup Instructions: +Cardiology: +Provider: [**First Name4 (NamePattern1) 4648**] [**Name Initial (NameIs) **] Phone: [**Telephone/Fax (1) 62**] Date/Time: +[**2102-9-12**] 2:20 +. +Primary Care: +Provider: [**First Name8 (NamePattern2) **] [**Name11 (NameIs) **], MD [**First Name8 (NamePattern2) 151**] [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **], MD Phone: +[**Telephone/Fax (1) 250**] Date/Time: [**9-6**] at 3:25pm. Please call +insurance and change PCP. +. +Gastroenterology: +Cystic lesion in tail of pancreas, not fully evaluated on this +examination. Would recommend MRI in 6 months for further +characterization. Pt needs to have a MR enterography and +colonoscopy as an outpt. + + + +",144,2102-08-14 20:53:00,2102-08-24 12:30:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ABDOMINAL PAIN," +the patient is a 41 year old female with seizure disorder, +gastrectomy, degenerative disc disease who presented with vague +gi complaints, weight loss, and admitted to ccu after an episode +of chest pain and she was found to have severe systolic/dystolic +function as well as tachycardia. on [**2102-8-24**], the +patient was discharged in good condition, with stable vital +signs, with appropriate outpatient follow-up arranged. +ms.[**known lastname 31410**] +. +# hypotension: has been intermittantly hypotensive this +admission but asymptomatic, likely [**1-2**] low ef. hct is low and +drfting down. random cortisol low normal and cortisone +stimulation test was normally responsive. pt is not orthostatic +or dizzy, is able to ambulate easily and denies any symptoms. +her lisinopril and metoprolol was started at a very low dose. +. +# upper back pain: pt has a history of lower back scoliosis, +myofascial pain syndrome and facet arthropathy that affects her +lower back. her upper back pain is new. pt feels that her pain +may be [**1-2**] bedrest, and is relieved by morphine. no radicular +symptoms. on muscle relaxer at home and chronic narcotics +(roxicet) which pt states is ineffective. pt reports that +clonazepam did not help as an additional muscle relaxer. she was +given a limited morphine po prescription and instructed to +contact the pain clinic at [**hospital1 18**] which she had used in [**2098**]. +according to the patient, they recommended surgery which she has +been reluctant to do. +. +# acute systolic dysfunction: cath [**8-21**] showed no cad. noted +increased filling pressures and furosemide and lasix po started. +no o2 requirement or sob at present despite fluid overload. +unclear etiology but fatigue in last few months may be related. +tsh neg. multiple viral tests performed, all negative except for +ebv and cmr which are pending. pt was discharged on lisinopril +2.5 mg and long acting metoprolol with furosemide twice daily. +instructed to weigh herself daily and follow a low sodium diet. +pt will follow-up with dr.[**name (ni) 3733**] for in [**month (only) 359**]. +. +# nausea, weight loss: pt had recent ct scan which showed +pancolitis, and f/u ct scan which showed interval resolution. +also w/ cholelithiasis and steatotic hepatitis. pt w/ fairly +substantial gi surgical hx. gi and surgery following with plan +for outpt ct colonoscopy for further evaluation. gi also +recommends outpatient mri enterography for further evaluation. +symptoms may represent malabsorption syndrome, such as celiac +sprue, or possibly related to surgical gastric resection. +albumin 2.0, thought to be contributing to her peripheral edema. +egd done, bx showed inflmmation only. weight loss is at least in +part r/t very decreased and erratic intake. pt describes very +poor protein and calorie intake last 2 months. spoke with pts +mother who states that pt has not worked in 2 months, is +considering disability, has been increasingly isolated in her +apt with limited contact with friends. dr. [**name (ni) 31411**], pts +outpatient psychiatrist was informed of this information. +worsening depression is suspected. she is tolerating pos at +discharge. she has had extensive nutritional counseling after +her gastric bypass but would consider outpatient referral again. + +. +# anemia: normochromic, normocytic. on fe supplementation as fe +studies suggest fe deficiency. no signs of acute bleed. had +some rectal bleeding with stools recently, [**1-2**] hemmorhoids. +needs repeat outpt colonoscopy. on fe, b12 q week, folic acid +supplements. +. +# epilepsy: no sz activity noted. continued home meds of +levetiracetam, venlafexime, topiramate +. +# depression: see note above about poor po intake. increasing +isolation, ahedonia and decreased intake all point to worsening +depression. psych team saw pt in house but had no +recommendations as they did not have accurate information from +the patient. outpt psychiatrist was contact[**name (ni) **] about symptoms and +will f/u with pt. note that pt is very reluctant to discuss some +information with her caregivers. + + ","PRIMARY: [Universal ulcerative (chronic) colitis] +SECONDARY: [Acute combined systolic and diastolic heart failure; Other protein-calorie malnutrition; Other and unspecified postsurgical nonabsorption; Unspecified disease of pericardium; Cyst and pseudocyst of pancreas; Loss of weight; Anorexia; Bariatric surgery status; Dehydration; Calculus of gallbladder without mention of cholecystitis, without mention of obstruction; Hepatitis, unspecified; Congestive heart failure, unspecified; Unspecified essential hypertension; Other chronic pulmonary heart diseases; Precordial pain; Spondylosis of unspecified site, without mention of myelopathy; Myalgia and myositis, unspecified; Other specified cardiac dysrhythmias; Scoliosis [and kyphoscoliosis], idiopathic; Other iatrogenic hypotension; Other antihypertensive agents causing adverse effects in therapeutic use; Depressive disorder, not elsewhere classified; Internal hemorrhoids with other complication; Iron deficiency anemia, unspecified; Epilepsy, unspecified, without mention of intractable epilepsy; Other disorders of plasma protein metabolism]" +66831,140947.0,8449,2130-07-27,8448,115882.0,2130-07-14,Discharge summary,"Admission Date: [**2130-7-10**] Discharge Date: [**2130-7-14**] + +Date of Birth: [**2047-4-25**] Sex: F + +Service: SURGERY + +Allergies: +Penicillins / Morphine / Codeine + +Attending:[**First Name3 (LF) 148**] +Chief Complaint: +Jaundice and abdominal pain. + +Major Surgical or Invasive Procedure: +[**2130-7-10**] - ERCP with stent removal and new stent placement. + + +History of Present Illness: +83 year-old female presents as transfer from [**Location (un) 620**] with +jaundice and abdominal pain. The patient has a known +peri-ampullary cancer. She had an ERCP in [**4-/2130**] that revealed +a bulky/friable major papilla and a 15 mm shouldered stricture +at the ampullary level. She was stented at that time. EUS 2 +days later revealed pancreas parenchyma with changes of chronic +pancreatitis. Changes of acute on chronic pancreatitis noted in +the head of the pancreas, and dilated pancreatic and bile duct +to the ampulla. Distal CBD brushings were positive for +malignancy. The patient is scheduled to have Whipple next week +by Dr. [**Last Name (STitle) **]. Patient was seen for preadmission testing last +week and was doing well. +. +However, she now presents 3 days of severe RUQ abdominal pain +and jaundice. Her urine has been dark, and she has been having +small brown bowel movements. She also reports vomiting on and +off for 4 days. She went to the ED at [**Hospital1 18**] [**Location (un) 620**] today where +she was found to be jaundiced and slightly hypotensive with SBP +in 80s. Her BP responded well to IVF. She was diagnosed with +cholangitis and transferred to [**Hospital1 18**] main campus for ERCP. At +the time of transfer, she was mentating well and not complaining +of any chest pain. She only felt slight abdominal pain. SBP +ranged from mid 80s to 110. + + +Past Medical History: +PMHx: AF (not on coumadin), CAD, HTN, Hypothyroidism, Type II +DM, +Hypercholesterolemia, Anemia, h/o Myasthenia [**Last Name (un) **], GERD, +Dysphagia, h/o Bronchitis, chronic pancreatitis, periampullary +cancer. +. +PSHx: TAH, Sinus surgery, ORIF UE fx w/ bone grafting + + +Social History: +Retired from work in accounting office and as florist. No +tobacco, alcohol, drugs. Patient will be discharged to a skilled +nursing facility, where her husband resides. + + +Family History: +Non-contributory + +Physical Exam: +On Admission: +VS: 98.0 116 104/62 18 96%2L +Gen: NAD. A&Ox3. +HEENT: Scleral icterus. Moist mucus membranes +Neck: No JVD. No LAD. No TM. +CV: RRR. +Pulm: CTAB. +Abd: Soft. NT. ND. +BS. +DRE: Normal tone. No masses. No gross or occult blood. +Ext: Warm and well perfused. No peripheral edema. +Neuro: Motor and sensation grossly intact. + + +Pertinent Results: +[**2130-7-10**] 10:48PM GLUCOSE-132* UREA N-35* CREAT-1.1 SODIUM-137 +POTASSIUM-3.7 CHLORIDE-107 TOTAL CO2-22 ANION GAP-12 +[**2130-7-10**] 10:48PM CALCIUM-7.3* PHOSPHATE-3.3 MAGNESIUM-2.0 +[**2130-7-10**] 10:48PM WBC-10.7 RBC-2.65* HGB-8.7* HCT-25.7* MCV-97 +MCH-32.9* MCHC-33.9 RDW-18.7* +[**2130-7-10**] 10:48PM NEUTS-94* BANDS-2 LYMPHS-3* MONOS-0 EOS-0 +BASOS-0 ATYPS-1* METAS-0 MYELOS-0 +[**2130-7-10**] 10:48PM HYPOCHROM-NORMAL ANISOCYT-2+ POIKILOCY-1+ +MACROCYT-2+ MICROCYT-1+ POLYCHROM-OCCASIONAL SPHEROCYT-1+ +OVALOCYT-1+ TARGET-OCCASIONAL SCHISTOCY-OCCASIONAL +STIPPLED-OCCASIONAL +[**2130-7-10**] 10:48PM PLT SMR-NORMAL PLT COUNT-232 +[**2130-7-10**] 10:48PM PT-15.1* PTT-25.9 INR(PT)-1.3* +[**2130-7-10**] 05:50PM URINE BLOOD-SM NITRITE-NEG PROTEIN-TR +GLUCOSE-NEG KETONE-NEG BILIRUBIN-LG UROBILNGN-1 PH-6.5 LEUK-NEG +[**2130-7-10**] 05:50PM URINE RBC-0-2 WBC-[**1-26**] BACTERIA-FEW YEAST-NONE +EPI-[**1-26**] +[**2130-7-10**] 04:45PM GLUCOSE-143* UREA N-39* CREAT-1.3* SODIUM-135 +POTASSIUM-3.7 CHLORIDE-103 TOTAL CO2-25 ANION GAP-11 +[**2130-7-10**] 04:45PM ALT(SGPT)-96* AST(SGOT)-155* CK(CPK)-72 ALK +PHOS-828* TOT BILI-8.4* +[**2130-7-10**] 04:45PM LIPASE-64* +[**2130-7-10**] 04:45PM cTropnT-0.29* +[**2130-7-10**] 04:45PM CK-MB-NotDone +[**2130-7-10**] 04:45PM ALBUMIN-2.4* +. +Cardiology Report ECG Study Date of [**2130-7-10**]: +Sinus tachycardia with atrial premature beats. Non-specific +diffuse low +amplitude T waves. Compared to the previous tracing of [**2130-7-6**] +sinus tachycardia is new and the Q-T interval is no longer +prolonged. + + Intervals Axes: +Rate PR QRS QT/QTc P QRS T +108 116 90 362/446 38 -2 12 +. +[**2130-7-10**] ERCP: +Distal migration of the pre-existing biliary stent in the major +papilla. Pus and sludge released from the bile duct following +removal of stent. +Biliary stricture consistent with the patients known ampullary +cancer. 10F 7cm Cotton [**Doctor Last Name **] biliary stent placed for drainage. +Otherwise normal EGD to third part of the duodenum. +. +Cardiology Report ECG Study Date of [**2130-7-11**]: +Sinus rhythm. T wave inversions in leads V1-V6. Cannot exclude +myocardial +ischemia. Prolonged Q-T interval. Low QRS voltage in the +precordial leads. +Compared to tracing #1 of [**2130-7-10**] sinus tachycardia and atrial +premature beats are absent. The T wave inversion is new. + Intervals Axes: +Rate PR QRS QT/QTc P QRS T +69 0 84 458/473 0 -9 -142 +. +[**2130-7-11**] CXR: Mild pulmonary edema with low lung volumes and +bibasilar +atelectasis. + +Brief Hospital Course: +The patient with a history of peri-ampullary cancer was admitted +from [**Hospital1 **] [**Location (un) 620**] ED to the SICU on [**2130-7-10**] in stable condition +for treatment of cholangitis. She was made NPO, started on IV +fluids and IV Cipro and Flagyl, a foley was placed, and she was +transfused 1 unit PRBC for a HCT 24.5 prior to ERCP. She then +underwent ERCP, which revealed distal migration of the +pre-existing biliary stent in the major papilla. Pus and sludge +released from the bile duct following removal of stent. Biliary +stricture consistent with the patients known ampullary cancer +was seen. A new stent was placed. The patient was then +transferred to the [**Hospital Unit Name 153**]. +. +[**Hospital Unit Name 153**] Course [**Date range (3) 29786**]: +The patient was transferred to the [**Hospital Unit Name 153**] post ERCP for monitoring +of respiratory status and continued intubation given her history +of myasthenia [**Last Name (un) 2902**]. She was hypotensive, and CVL and A-line +were placed. She received LR boluses and was started on levophed +drip with improvement in her CVP to 16-18 and MAPs>70. UOP was +approximately 20-25cc/hr. Troponin's elevated 0.19-0.29 range; +no EKG changes or ST elevation. Recent persantine stress test +normal. Believed to be due to demand ischemia secondary to +hypotensive episode and/or sepsis. No acute cardiac events. The +patient was extubated without events and transferred to the SICU +for continued management. +. +SICU Course [**Date range (3) 29787**]: +Returned to SICU NPO except medications, on IV fluids and IV +antibiotics in good condition and hemodynamically stable. +Electrolytes repleted, started on sips and home medications, +ambulated. Cleared for transfer to the floor. +. +Floor Course [**Date range (3) 29788**]: +Tranferred to the floor; was hemodynamically stable. Diet +abvanced to clears, then regular by [**2130-7-13**] with good +tolerability. Experienced no significant pain. IV fluids +discontinued. Foley catheter was discontinued; the patient was +able to void on her own without problem. Restarted on remaining +home medications with the exception of Metoprolol, which was +prescribed as 100mg [**Hospital1 **] as blood pressure and heart rate well +controlled, instead of home dose of Toprol XL 250mg daily. +Physical Therapy evaluated and worked with the patient prior to +discharge. + +At the time of discharge on [**2130-7-14**], the patient was doing well, +afebrile with stable vital signs. The patient was tolerating a +regular diet, ambulating with assistance, voiding without +assistance, and not experiencing any significant pain. The +patient was discharged to the same skilled nursing facility, +where her husband has been admitted. She will return for planned +Whipple surgery [**2130-8-2**]. The patient received discharge teaching +and follow-up instructions with understanding verbalized and +agreement with the discharge plan. + +Medications on Admission: +1. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Mirtazapine 15 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +4. Aspirin EC 325 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +5. Metformin 500 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO DAILY (Daily). +6. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. +7. Lovastatin 40 mg Tablet Sig: One (1) Tablet PO at bedtime. +8. Lisinopril 40 mg Tablet Sig: One (1) Tablet PO once a day. +9. Mestinon 60 mg Tablet Sig: One (1) Tablet PO twice a day. +10. Alprazolam 0.25 mg Tablet Sig: One (1) Tablet PO as needed +for Anxiety. +11. Imuran 50mg PO BID. +12. Metoprolol SR 250mg (200mg + 50mg) PO daily. +13. HCTZ 25mg PO QAM. + +Discharge Medications: +1. Levothyroxine 125 mcg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Amiodarone 200 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +3. Mirtazapine 15 mg Tablet Sig: One (1) Tablet PO HS (at +bedtime). +4. Aspirin 325 mg Tablet Sig: One (1) Tablet PO DAILY (Daily): +Hold Aspirin starting [**2130-7-19**] (two weeks prior to surgery). +5. Metformin 500 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO DAILY (Daily). +6. Omeprazole 20 mg Capsule, Delayed Release(E.C.) Sig: One (1) +Capsule, Delayed Release(E.C.) PO once a day. +7. Lovastatin 20 mg Tablet Sig: One (1) Tablet PO at bedtime. +8. Lisinopril 40 mg Tablet Sig: One (1) Tablet PO once a day. +9. Mestinon 60 mg Tablet Sig: One (1) Tablet PO twice a day. +10. Alprazolam 0.25 mg Tablet Sig: One (1) Tablet PO Qday-[**Hospital1 **] as +needed for Anxiety. +11. Metronidazole 500 mg Tablet Sig: One (1) Tablet PO Q8H +(every 8 hours) for 9 days. +Disp:*27 Tablet(s)* Refills:*0* +12. Ciprofloxacin 500 mg Tablet Sig: One (1) Tablet PO Q12H +(every 12 hours) for 9 days. +Disp:*18 Tablet(s)* Refills:*0* +13. Hydrochlorothiazide 25 mg Tablet Sig: One (1) Tablet PO +DAILY (Daily). +14. Metoprolol Tartrate 100 mg Tablet Sig: One (1) Tablet PO +twice a day: [**Month (only) 116**] increase to 200mg [**Hospital1 **] if indicated by BP & HR. + +15. Azathioprine 50 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +16. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO every [**2-27**] +hours as needed for fever or pain. + + +Discharge Disposition: +Extended Care + +Facility: +[**Location (un) 29789**] Country Manor - [**Location (un) 29789**] + +Discharge Diagnosis: +1. Periampullary cancer +2. Cholangitis +3. [**First Name9 (NamePattern2) **] [**Last Name (un) **] +4. Anemia + + +Discharge Condition: +Stable + + +Discharge Instructions: +Please call your doctor or nurse practitioner or return to the +Emergency Department for any of the following: + +*You experience new chest pain, pressure, squeezing or +tightness. +*New or worsening cough, shortness of breath, or wheeze. +*If you are vomiting and cannot keep down fluids or your +medications. +*You are getting dehydrated due to continued vomiting, diarrhea, +or other reasons. Signs of dehydration include dry mouth, rapid +heartbeat, or feeling dizzy or faint when standing. +*You see blood or dark/black material when you vomit or have a +bowel movement. +*You experience burning when you urinate, have blood in your +urine, or experience a discharge. +*Your pain is not improving within 8-12 hours or is not gone +within 24 hours. Call or return immediately if your pain is +getting worse or changes location or moving to your chest or +back. +*You have shaking chills, or fever greater than 101.5 degrees +Fahrenheit or 38 degrees Celsius. +*Any change in your symptoms, or any new symptoms that concern +you. + +Please resume all regular home medications , unless specifically +advised not to take a particular medication. Also, please take +any new medications as prescribed. + +Please get plenty of rest, continue to ambulate several times +per day, and drink adequate amounts of fluids. Avoid lifting +weights greater than [**4-2**] lbs until you follow-up with your +surgeon. + +Avoid driving or operating heavy machinery while taking pain +medications. + +Followup Instructions: +You have been scheduled for Whipple surgery on [**2130-8-2**]. Please +take nothing by mouth after midnight on [**8-2**]. Stop your Aspirin +on [**2130-7-19**]. Please do NOT take your Metformin and +hydrochlorothiazide the morning of surgery. You will be +contact[**Name (NI) **] with other pre-operative instructions prior to this +date. Please call Dr.[**Name (NI) 2829**] Office at ([**Telephone/Fax (1) 2828**] with any +questions. + +Please call ([**Telephone/Fax (1) 7761**] to arrange a follow-up appointment +with Dr. [**Last Name (STitle) **] (PCP) in [**11-25**] weeks. + + + +Completed by:[**2130-7-14**]",13,2130-07-10 17:25:00,2130-07-14 14:25:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,ABDOMINAL PAIN," +the patient with a history of peri-ampullary cancer was admitted +from [**hospital1 **] [**location (un) 620**] ed to the sicu on [**2130-7-10**] in stable condition +for treatment of cholangitis. she was made npo, started on iv +fluids and iv cipro and flagyl, a foley was placed, and she was +transfused 1 unit prbc for a hct 24.5 prior to ercp. she then +underwent ercp, which revealed distal migration of the +pre-existing biliary stent in the major papilla. pus and sludge +released from the bile duct following removal of stent. biliary +stricture consistent with the patients known ampullary cancer +was seen. a new stent was placed. the patient was then +transferred to the [**hospital unit name 153**]. +. +[**hospital unit name 153**] course [**date range (3) 29786**]: +the patient was transferred to the [**hospital unit name 153**] post ercp for monitoring +of respiratory status and continued intubation given her history +of myasthenia [**last name (un) 2902**]. she was hypotensive, and cvl and a-line +were placed. she received lr boluses and was started on levophed +drip with improvement in her cvp to 16-18 and maps>70. uop was +approximately 20-25cc/hr. troponins elevated 0.19-0.29 range; +no ekg changes or st elevation. recent persantine stress test +normal. believed to be due to demand ischemia secondary to +hypotensive episode and/or sepsis. no acute cardiac events. the +patient was extubated without events and transferred to the sicu +for continued management. +. +sicu course [**date range (3) 29787**]: +returned to sicu npo except medications, on iv fluids and iv +antibiotics in good condition and hemodynamically stable. +electrolytes repleted, started on sips and home medications, +ambulated. cleared for transfer to the floor. +. +floor course [**date range (3) 29788**]: +tranferred to the floor; was hemodynamically stable. diet +abvanced to clears, then regular by [**2130-7-13**] with good +tolerability. experienced no significant pain. iv fluids +discontinued. foley catheter was discontinued; the patient was +able to void on her own without problem. restarted on remaining +home medications with the exception of metoprolol, which was +prescribed as 100mg [**hospital1 **] as blood pressure and heart rate well +controlled, instead of home dose of toprol xl 250mg daily. +physical therapy evaluated and worked with the patient prior to +discharge. + +at the time of discharge on [**2130-7-14**], the patient was doing well, +afebrile with stable vital signs. the patient was tolerating a +regular diet, ambulating with assistance, voiding without +assistance, and not experiencing any significant pain. the +patient was discharged to the same skilled nursing facility, +where her husband has been admitted. she will return for planned +whipple surgery [**2130-8-2**]. the patient received discharge teaching +and follow-up instructions with understanding verbalized and +agreement with the discharge plan. + + ","PRIMARY: [Unspecified septicemia] +SECONDARY: [Septic shock; Cholangitis; Obstruction of bile duct; Malignant neoplasm of extrahepatic bile ducts; Chronic pancreatitis; Acute kidney failure, unspecified; Severe sepsis; Atrial fibrillation; Unspecified essential hypertension; Unspecified acquired hypothyroidism; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Myasthenia gravis without (acute) exacerbation]" +68140,112268.0,18626,2157-03-01,18625,190006.0,2157-02-16,Discharge summary,"Admission Date: [**2157-1-19**] Discharge Date: [**2157-2-16**] + +Date of Birth: [**2073-4-5**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins / Bactrim + +Attending:[**First Name3 (LF) 898**] +Chief Complaint: +Transfer from [**First Name4 (NamePattern1) 2299**] [**Last Name (NamePattern1) **] NH for hypotension and hypoxia + +Major Surgical or Invasive Procedure: +none + + +History of Present Illness: +Mr. [**Known lastname 1683**] is an 83 YOM with dementia, Type 2 Diabetes Mellitus, +bladder cancer s/p resection and BCG treatment, and recently +discharged for UTI who was at his nursing home yestderday when +found to be having chills and lower extremity numbness. His +vitals were taken and was found to be afebrile 95.7, hypotensive +(79/57), tachycardic (120) and hypoxic (O2SAT: 81% on RA). His +bilateral LE were found to be cold and purple. He was warmed up +and put into bed and his BP stabilized in 110s, he was placed on +nonrebreather and his O2 sats came up only to 87%. Per records +he did not have any mental status changes. +. +Of note, OSH records from Mr [**Known lastname 1683**] previous D/C summary in OMR +report he has had multiple recent UTIs over the past few months +including multi drug resistent enterobacter on [**2156-12-12**], Proteus +on [**2156-12-20**], as well as Klebsiella in [**Month (only) 359**]. Mr. [**Known lastname 1683**] was +recently discharged from [**Hospital1 **] on [**2156-12-31**] for UTI with pseudomonas +resistent to cipro. This admission was complicated by delirium +and LE DVT for which an IVC filter was placed due to concurrent +hematuria. He is not currently anticoagulated. He was discharged +on meropenem for 6 days. On [**2157-1-18**] (the day prior to admission) +he presented to the ED b/c of hematuria and passage of clots. He +was seen by urology and foley irrigation was performed and he +was sent out on Levofloxacin with plans to undergo cystoscopy +with bladder biopsies and possible +resection of TURBT as an outpatient. However, the following day +he had his hypotensive event described above and was sent to the +ED. +. +In the ED his vitals were 98.0 110 130/60 18 99. However, his BP +dropped to 90/60 BP with sats in the 80s and a lactate of 6. CXR +showed no acute pulmonary process. He was given vanc and +meropenem and, had an IJ placed, 6 L fluid, and foley showed +gross hematuria. He was transfered to the MICU with concern for +urosepsis where his pressure stabilized and he did not require +pressors. He was transfered to the medicine floor. +. +Upon ariving to the floor vitals were 99.2 122/60 91 20 97% on +RA. +. +ROS: Difficult to understand pt, unsure if from dementia or +adentulous. Pt alert but oriented only to self, knew he was in +[**Location (un) 86**] but could not name hospital. Denied pain, SOB, but stated +he was cold and thirsty. + +Past Medical History: +1. Pulmonary Embolism ([**2156-12-24**], IVC filter, not on +anticoagulation) +2. Pancreatitis +3. Dementia +4. Type 2 Diabetes Mellitus +5. Hypertension, but not on antihypertensives +6. BPH +7. Bladder Cancer +- s/p transurethral resection in [**7-31**] +- completed [**3-29**] BCG treatment (missed treatment 5 [**1-25**] UTI) +8. s/p Stab Wounds +9. h/o RPR - treated in [**2119**] +10. s/p Penile Implant +11. Osteoarthritis + +Social History: +Per previous records, patient could not complete full history +with me due to his delirium and dementia. + +Home: lives in [**Location 4367**] [**Hospital3 400**] Facility +Occupation: retired long-distance truck driver +EtOH: remote history of social alcohol use; denies EtOH in > 45 +years +Tobacco: remote history of 1 PPD smoking history, could not tell +me when he quit +Drugs: denies + + +Family History: +Could not complete due to patient's dementia. + +Physical Exam: +VS: 100.4 133/74 76 20 98% RA +General: Alert, oriented to self only, lying comfortably in bed +HEENT: Dry mucous membranes, edentulous, pupils equal and +reactive +Neck: supple, JVP not elevated, no LAD. Right IJ in place, +appears clean and dry. +Lungs: Clear to auscultation bilaterally, no wheezes, rales, +ronchi +CV: Regular rate and rhythm, normal S1 + S2, no murmurs, rubs, +gallops +Abdomen: soft, non-tender, non-distended, bowel sounds present, +no rebound tenderness or guarding, no organomegaly +Ext: 2+ pitting edema in left LE and 1+ on right, chronic venous +stasis changes to skin of both LEs; DPs difficult to palpate, +but feet are warm +Neuro: CN grossly intact. Uses both upper extremities +purposefully. +Foley with red urine in bag. Responded to questions, but +difficult to make out his answers, mildly agitated, not really +holding coherent conversation. + +Pertinent Results: +LABS ON ADMISSION: + +[**2157-1-18**] 10:00AM BLOOD WBC-11.7* RBC-4.20* Hgb-10.4* Hct-32.8* +MCV-78* MCH-24.8* MCHC-31.7 RDW-14.7 Plt Ct-257 +[**2157-1-18**] 10:00AM BLOOD Neuts-82.9* Lymphs-11.6* Monos-4.7 +Eos-0.4 Baso-0.3 +[**2157-1-18**] 10:00AM BLOOD PT-14.4* PTT-26.4 INR(PT)-1.2* +[**2157-1-18**] 10:00AM BLOOD Glucose-138* UreaN-33* Creat-1.3* Na-144 +K-3.9 Cl-100 HCO3-30 AnGap-18 +[**2157-1-19**] 05:25PM BLOOD ALT-17 AST-16 LD(LDH)-268* AlkPhos-76 +TotBili-0.3 +[**2157-1-19**] 05:25PM BLOOD Lipase-68* +[**2157-1-19**] 05:25PM BLOOD cTropnT-<0.01 +[**2157-1-19**] 07:43PM BLOOD Hgb-8.4* calcHCT-25 O2 Sat-91 +[**2157-1-19**] 08:48PM BLOOD Glucose-133* Lactate-1.2 +[**2157-1-19**] 05:22PM BLOOD Lactate-6.0* K-5.0 + +LABS ON DISCHARGE: +[**2157-2-14**] 05:53AM BLOOD WBC-6.6 RBC-3.38* Hgb-7.9* Hct-26.0* +MCV-77* MCH-23.2* MCHC-30.2* RDW-18.1* Plt Ct-423 +[**2157-2-15**] 06:56AM BLOOD WBC-8.0 RBC-3.57* Hgb-8.2* Hct-27.5* +MCV-77* MCH-23.0* MCHC-29.8* RDW-17.5* Plt Ct-421 +[**2157-2-15**] 06:56AM BLOOD Glucose-141* UreaN-12 Creat-0.6 Na-136 +K-4.5 Cl-99 HCO3-29 AnGap-13 +[**2157-2-15**] 06:56AM BLOOD Calcium-9.0 Phos-3.0 Mg-1.6 +[**2157-2-16**] 05:43AM BLOOD WBC-7.6 RBC-3.50* Hgb-8.2* Hct-26.6* +MCV-76* MCH-23.5* MCHC-30.9* RDW-18.0* Plt Ct-495* +[**2157-2-16**] 05:43AM BLOOD Glucose-144* UreaN-11 Creat-0.6 Na-134 +K-4.3 Cl-97 HCO3-30 AnGap-11 +[**2157-2-16**] 05:43AM BLOOD Calcium-9.1 Phos-2.9 Mg-1.8 +******** +CXR [**2157-1-20**]: FINDINGS: Lung volumes are markedly diminished with +resultant bronchovascular +reorientation at the lung bases. No consolidation or edema is +evident. Tortuosity of the thoracic aorta is slightly +accentuated due to the low lung volumes. Similarly, cardiac size +is mildly accentuated, but remains overall within normal limits. +No definite effusion or pneumothorax is seen. Extensive +degenerative changes are again seen throughout the thoracic +spine. There are multiple bilateral rib deformities, presumably +due to remote trauma, relatively stable when compared to the +prior exam. IMPRESSION: Markedly low lung volumes with no acute +pulmonary process identified. + +RENAL U/S: FINDINGS: The right kidney measures 11.0 cm. The left +kidney measures 13.1 cm. No stones, hydronephrosis or solid mass +is identified. Within the lower pole of the right kidney is a +1.6 cm simple-appearing cyst. There is also a 1.6 cm +simple-appearing cyst within the upper pole of the left kidney. +No perinephric fluid collection is identified. +Limited views of bladder reveal Foley catheter, with the bladder +decompressed. There is a heterogeneous 6.7 cm mass in the +bladder with vascular waveforms obtained, compatible with the +patient's known bladder mass. +IMPRESSION: +1. No evidence of hydronephrosis. +2. No evidence of perinephric abscess or fluid. + +CXR [**2-9**]: Cardiomediastinal silhouette is stable. Right PICC +line tip is at the level of superior SVC. Heart size is normal. +Mediastinal contour is unremarkable. There is questionable new +small focal opacity at the mid portion of the left lung that +might represent subpleural atelectasis/nodule seen on the chest +CT from [**2157-1-29**], with no new consolidations +demonstrated. The known pulmonary nodules are partially imaged +on the current study due to the suboptimal sensitivity of this +portable chest radiograph. Multiple rib fractures, bilateral, +are unchanged since the prior study. The IVC filter is in place. + + +. +CT CHEST WITHOUT IV CONTRAST: There are numerous pulmonary +nodules throughout all lobes of the lungs consistent with +metastatic disease, presumably from the patient's known bladder +cancer unless there is an additional unknown primary neoplasm. +These are larger in the lung bases, measuring up to 12 mm +bilaterally (2:36, 2:34). There is no significant pleural +effusion. There is bilateral mild subsegmental dependent +atelectasis. The trachea and bronchi are patent to the +subsegmental levels. There is no mediastinal lymphadenopathy. +Note is made of multiple slightly prominent axillary lymph +nodes, which are not pathologically enlarged by size criteria. +There are numerous coronary artery calcifications, as well as +calcification of the aortic arch. A right upper extremity PICC +terminates with the catheter tip in the lower SVC. Limited axial +imaging of the upper abdomen is fairly unremarkable, although +numerous renal hypodensities are again seen, which are most +consistent with cysts, although better demonstrated on prior +imaging studies. The superior most aspect of an infrarenal IVC +filter is seen (2:56). Small hiatal hernia is present. +Osseous structures demonstrate numerous left-sided chronic rib +fractures at T1-9 as well as right-sided rib fractures at T1-6. +No suspicious lytic or sclerotic lesions are seen. There is mild +degenerative change of the thoracic spine. + +IMPRESSION: 1. Innumerable bilateral pulmonary nodules +consistent with metastatic disease. +2. No mediastinal lymphadenopathy. +3. Chronic rib fractures bilaterally. +4. Renal hypodensities most consistent with cysts, better +demonstrated on +prior studies. + +Brief Hospital Course: +83yo gentleman with h/o bladder cancer, recurrent UTIs, and +dementia called out from the MICU for continuing treatment of +urosepsis. Hospital course by problem as follows. +. +# Urosepsis: Patient received 7 L IVF with improvement in blood +pressure, never needed vasopressor support. He was started on +meropenem given prior urine cx sensitivities. He was transferred +to the floor the following morning. His renal function returned +to baseline after volume repletion. UCx pseudomonas 10-100k, +sensitive to cefepime, ceftaz, gent, [**Last Name (un) 2830**], [**Doctor Last Name **], tobra. +Recurrent UTIs across last several months with documented +history of proteus, enterobacter, klebsiela and pseudomonas, +current urine cx showing pseudomonas. No other clear source of +infection as he did not have infiltrate on CXR, no cough, no +abdominal pain, BCx NGTD, and no lines on admission. PICC line +placed and he was treated for 14days with meropenem. Urology +consulted. Recurrent UTI's likely [**1-25**] bladder cancer and +urinary retention. A Foley catheter was placed at admission. +This was taken out overnight on [**2-15**]. He passed his trial of +void with a 100 cc residual volume. He was noted to be +incontinent of urine at baseline. +. +# Bladder cancer, hematuria: Urology took for cystoscopy-> 7cm +tumor, unable to resect via scope. CT to assess for invasion/ +lymph node involvement-> no clear evid of invasion or LN +involvement however mult lung nodules concerning for metastatic +disease. Med onc consulted-> Rec chest CT for accurate +staging, bx for tissue diagnosis, and agreed to follow when +outpatient. Given massive DVT and need for anticoagulation, +discussion had with family/urology/ radiation oncology about +possible palliative procedures to stop hematuria and allow for +anticoagulation. Decision was made to proceed with palliative +radiation tx as family wished to avoid any further invasive +procedures. Palliative care also consulted. Patient underwent +palliative radiation in attempt to control hematuria so that he +could have anticoagulation given his large lower extremity DVT +as below. +. +# DVT: h/o PE [**1-25**] DVT with IVC in place not anticoagulated due +to history of hematuria. Patient noted to have swollen L leg-> +LENI-> DVT from L common fem to L popliteal. CT scan done for +staging as above showed DVT extended up to DVT filter. +Anticoagulation attempted however was d/c'd as hematuria +increased and patient dropped his hct. Palliative radiation +therapy was given with the goal to control hematuria, however +the patient did continue to bleed with anticoagulation. Given +that he bled enough to require multiple transfusions during this +admission, it was ultimately felt that anticoagulation should be +held with the decision to re-start deferred to the outpatient +setting. +. +# Low grade fevers: Following treatment with meropenem for +urosepsis as above, patient developed recurrent low grade +fevers. No clear source. UCx, BCx, and CXR negative for +infection. WBC stable. In the end, thought likely due to DVT. +By discharge, still having once daily temperatures to 99 F. +. +# Delirium : Continued on aricept. MS waxed and waned however +never returned to baseline. He frequently became agitated, +pulling at his PICC line and foley. He frequently required soft +restraints to prevent him from injuring himself and occasionally +required haldol (ECG checked and QTc wnl). After his catheter +was removed the restraints were removed and he was overall much +more calm. +. +# Anemia: baseline Hct 32-35, current Hct 25, likely [**1-25**] +hematuria. Iron studies were consistent with underlying anemia +of chronic disease. Guiac was negative. He was transfused a +total of 5 units of PRBCs during this admission given blood loss +from his friable bladder tumor. His Hct was stable around 26 +prior to discharge. +. +# Hypernatremia, Mild, Asymptomatic: likely [**1-25**] poor PO water +intake. Encouraged PO intake of water and this resolved on its +own. +. +# Type 2 DM: controlled with ISS in house. + +Medications on Admission: +Imipenem 750mg [**Hospital1 **] IM started [**2157-1-3**] for 3 days +Ertapenem 1gm IM Qday x 4 days, started [**2157-1-3**] +Decubrite 1 tab Qday +tylenol 650mg Q4H PO PRN +Lasix 30mg PO qday +Levaquin 250mg PO x 7 days, started [**2157-1-18**] +Donepezil 5mg HS +Gabapentin 300mg Qday +Imdur 30mg Qday +Famotidine 20mg PO BID PRN itch +Novalog SSI +Senna 1-2 tabs [**Hospital1 **] PRN +Vitamin D3 400mg, 2 tabs Qday +Colace 100mg [**Hospital1 **] +Citaloprom 20mg Qday + +Discharge Medications: +1. Famotidine 20 mg Tablet Sig: One (1) Tablet PO every twelve +(12) hours. +Disp:*30 Tablet(s)* Refills:*2* +2. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). Tablet(s) +3. Citalopram 20 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Donepezil 5 mg Tablet Sig: One (1) Tablet PO HS (at bedtime). + +5. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +6. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO BID (2 +times a day). +7. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for fever or pain. +8. Polyvinyl Alcohol 1.4 % Drops Sig: 1-2 Drops Ophthalmic PRN +(as needed) as needed for dryness. +Disp:*1 bottle* Refills:*2* +9. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) +Injection TID (3 times a day). +10. Nystatin 100,000 unit/mL Suspension Sig: Five (5) ML PO QID +(4 times a day). +11. Polyethylene Glycol 3350 17 gram/dose Powder Sig: One (1) +packet PO DAILY (Daily) as needed for constipation. +12. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: Two (2) +Tablet PO DAILY (Daily). +13. Insulin Instructions +Please continue to take your Humalog Insulin --Sliding Scale as +taken during this admission. A full sliding scale regimen is +outlined below for the [**First Name4 (NamePattern1) 1188**] [**Last Name (NamePattern1) **] nurses to follow. To be +taken as needed at meal times and at bed time + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital3 1186**] - [**Location (un) 538**] + +Discharge Diagnosis: +PRIMARY: +1. Urosepsis +2. Bladder Cancer +3. Deep venous thrombosis +SECONDARY: +1. Dementia / deliriium +2. Type 2 Diabetes Mellitus +3. Hypertension, but not on antihypertensives + + +Discharge Condition: +Mental Status:Confused - always +Level of Consciousness: Lethargic but arousable +Activity Status: Bedbound + + +Discharge Instructions: +It was a pleasure taking care of you during your admission at +[**Hospital1 69**]. You were admitted for a +urinary tract infection. You were treated with antibiotics. You +had a catheter in your bladder for some time, but we took this +out and you were able to urinate on your own. + +You received a course of radiation to help improve your bladder +cancer symptoms. + +You have a previous diagnosis of left lower leg blood clot. We +were unable to give you anticoagulant medications for this as +you continued to have significant blood in your urine, requiring +blood transfusion, after receiving these. + +We have changed some of your medications during your admission. +Please continue, start, or stop your medications as below: + +- Continue Citalopram 20 mg daily +- Continue Donepezil 5 mg daily +- Continue Famotidine 20 mg twice daily +- Continue polyethylene glycol for constipation as needed +- Continue Senna for constipation prevention +- Continue Vitamin D 800 units daily +- Stop Fexofenadine +- Continue Colace 100 mg twice daily +- Continue Tylenol as needed for pain/fever as written +- Continue using Humalog Insulin as needed with a sliding scale +at meal times and bedtime as taken prior to this admission +- Stop Lasix; discuss re-starting this medication as an +outpatient. +- Continue getting subcutaneous heparin three times daily while +in [**First Name4 (NamePattern1) 2299**] [**Last Name (NamePattern1) **] + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) **]. [**Doctor Last Name **] and Dr. [**Last Name (STitle) 10351**] from +urologic oncology on [**3-10**] at 1 pm. +. +Dr.[**Name (NI) 51133**] office was called and notified that you will be +going back to The [**First Name4 (NamePattern1) 2299**] [**Last Name (NamePattern1) **]. Upon return to the [**First Name4 (NamePattern1) 2299**] +[**Last Name (NamePattern1) **] you will be seen by her nurse practitioner, Jiyan [**Doctor Last Name **] +(#[**Telephone/Fax (1) 608**]). Ms. [**Name13 (STitle) **] will help to coordinate your next +visit with Dr. [**Last Name (STitle) 4321**] at your facility. + + + +Completed by:[**2157-2-16**]",13,2157-01-19 20:13:00,2157-02-16 17:20:00,EMERGENCY,EMERGENCY ROOM ADMIT,SNF,SEPSIS," +83yo gentleman with h/o bladder cancer, recurrent utis, and +dementia called out from the micu for continuing treatment of +urosepsis. hospital course by problem as follows. +. +# urosepsis: patient received 7 l ivf with improvement in blood +pressure, never needed vasopressor support. he was started on +meropenem given prior urine cx sensitivities. he was transferred +to the floor the following morning. his renal function returned +to baseline after volume repletion. ucx pseudomonas 10-100k, +sensitive to cefepime, ceftaz, gent, [**last name (un) 2830**], [**doctor last name **], tobra. +recurrent utis across last several months with documented +history of proteus, enterobacter, klebsiela and pseudomonas, +current urine cx showing pseudomonas. no other clear source of +infection as he did not have infiltrate on cxr, no cough, no +abdominal pain, bcx ngtd, and no lines on admission. picc line +placed and he was treated for 14days with meropenem. urology +consulted. recurrent utis likely [**1-25**] bladder cancer and +urinary retention. a foley catheter was placed at admission. +this was taken out overnight on [**2-15**]. he passed his trial of +void with a 100 cc residual volume. he was noted to be +incontinent of urine at baseline. +. +# bladder cancer, hematuria: urology took for cystoscopy-> 7cm +tumor, unable to resect via scope. ct to assess for invasion/ +lymph node involvement-> no clear evid of invasion or ln +involvement however mult lung nodules concerning for metastatic +disease. med onc consulted-> rec chest ct for accurate +staging, bx for tissue diagnosis, and agreed to follow when +outpatient. given massive dvt and need for anticoagulation, +discussion had with family/urology/ radiation oncology about +possible palliative procedures to stop hematuria and allow for +anticoagulation. decision was made to proceed with palliative +radiation tx as family wished to avoid any further invasive +procedures. palliative care also consulted. patient underwent +palliative radiation in attempt to control hematuria so that he +could have anticoagulation given his large lower extremity dvt +as below. +. +# dvt: h/o pe [**1-25**] dvt with ivc in place not anticoagulated due +to history of hematuria. patient noted to have swollen l leg-> +leni-> dvt from l common fem to l popliteal. ct scan done for +staging as above showed dvt extended up to dvt filter. +anticoagulation attempted however was d/cd as hematuria +increased and patient dropped his hct. palliative radiation +therapy was given with the goal to control hematuria, however +the patient did continue to bleed with anticoagulation. given +that he bled enough to require multiple transfusions during this +admission, it was ultimately felt that anticoagulation should be +held with the decision to re-start deferred to the outpatient +setting. +. +# low grade fevers: following treatment with meropenem for +urosepsis as above, patient developed recurrent low grade +fevers. no clear source. ucx, bcx, and cxr negative for +infection. wbc stable. in the end, thought likely due to dvt. +by discharge, still having once daily temperatures to 99 f. +. +# delirium : continued on aricept. ms waxed and waned however +never returned to baseline. he frequently became agitated, +pulling at his picc line and foley. he frequently required soft +restraints to prevent him from injuring himself and occasionally +required haldol (ecg checked and qtc wnl). after his catheter +was removed the restraints were removed and he was overall much +more calm. +. +# anemia: baseline hct 32-35, current hct 25, likely [**1-25**] +hematuria. iron studies were consistent with underlying anemia +of chronic disease. guiac was negative. he was transfused a +total of 5 units of prbcs during this admission given blood loss +from his friable bladder tumor. his hct was stable around 26 +prior to discharge. +. +# hypernatremia, mild, asymptomatic: likely [**1-25**] poor po water +intake. encouraged po intake of water and this resolved on its +own. +. +# type 2 dm: controlled with iss in house. + + ","PRIMARY: [Unspecified septicemia] +SECONDARY: [Septic shock; Acute kidney failure, unspecified; Urinary tract infection, site not specified; Acute venous embolism and thrombosis of deep vessels of proximal lower extremity; Acidosis; Hyposmolality and/or hyponatremia; Hyperosmolality and/or hypernatremia; Acute posthemorrhagic anemia; Pseudomonas infection in conditions classified elsewhere and of unspecified site; Malignant neoplasm of dome of urinary bladder; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Gross hematuria; Unspecified essential hypertension; Hypertrophy (benign) of prostate with urinary obstruction and other lower urinary tract symptoms (LUTS); Retention of urine, unspecified; Severe sepsis; Other transfusion reaction; Other specified procedures as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Hypoxemia; Other persistent mental disorders due to conditions classified elsewhere]" +73488,199332.0,17651,2169-12-09,17650,185762.0,2169-10-23,Discharge summary,"Admission Date: [**2169-10-14**] Discharge Date: [**2169-10-23**] + +Date of Birth: [**2130-2-9**] Sex: M + +Service: MEDICINE + +Allergies: +Ampicillin / Ancef + +Attending:[**First Name3 (LF) 689**] +Chief Complaint: +hypoxia, seizure + +Major Surgical or Invasive Procedure: +intubation for airway protection + + +History of Present Illness: +This is a 39 yom with h/o C5 quadriplegia, MDS, and recurrent +UTIs who was transferred from OSH for assessment of altered +mental status. He was admitted to [**Location (un) 620**] from [**2169-10-5**] to +[**2169-10-9**] with lethargy and was diagnosed with a Klebsiella UTI. +He was initially treated with ertapenem and subsequently +switched to ciprofloxacin for a seven day course. At the time of +discharge the patient was continuing to feel weak. At baseline +he can unscrew a bottle cap, drive a car and drive his +wheelchair. He returned to [**Location 620**] on [**2169-10-14**] with progressive +weakness in his upper extremities and lethargy. His temperature +was ""running low"" but he had no fevers, chest pain, difficulty +breathing, nausesa, vomiting, headaches, neck stiffness, head +trauma or diarrhea but was having some mild cough and +congestion. Initial vitals were notable for a temperature of +92.7. Initial urinalysis was positive and he was started on +ertapenem for presumed urinary tract infection. Subsequent +culture has been negative. He had a head CT which showed +possible blood in the third ventricle. He was transfered to this +hospital for further management. +. +On arrival to our emergency room his initial vs were: T 96.2 P: +61 BP: 120/71 R: 14 O2 sat 96%RA. He was seen by neurosurgery +who felt he should have platelets given but no surgery was +indicated. Patient was given 6 units of platelets (1 bag) and +transferred to the floor. +. +On admission the patient was noted A&O x 3 but per his family +was more lethargic than usual. Upper extremity strength was +documented as as 4-/5. On [**2169-10-15**], pt had a generalized tonic +clonic seizure with hypoxia of 88% on RA. He was treated with IV +ativan and was subsequently post-ictal. He was placed on +continuous oxygen monitoring and four liters nasal cannula with +saturations in the mid 90s. There was concern for aspiration +during this event secondary to increased secretions requiring +deep suctioning. He was started on IV Keppra 1000 mg [**Hospital1 **]. EEG +showed left mid to posterior temporal theta slowing. On [**2169-10-17**] +he had a second generalized tonic clonic seizure lasting one +minute. He was given IV ativan and subsequently was noted to +have hypoxia to 85% on 4L nasal cannula and his respiratory rate +was [**5-1**] with periods of apnea. CPAP was tried, but hypoxia +persisted. He was placed on NRB. +. +Complicating his hospital course was a multifocal pneumonia +noted on CXR, with low grade temps. He was cotninued on +meropenem for UTI although cultures subsequently returned as +negative. +. +MICU course: Pt was somnolent but arousing to voice. He did not +respond to questions but would track when aroused. He did not +withdraw to painful stimuli in the upper extremtities or respond +to questions. Pt is noted to have episodes of bradycardia +associated with hypothermia. ECG shows no apparent heart block. + Antibiotic coverage was broadened to include anaerobes with +Flagyl. Pt was continued on Keppra and Dilantin. +. +Currently, pt feels well. Denies any complaints. He denies any +discomfort with his breathing. +. +ROS: Denies fever, chills, night sweats, headache, rhinorrhea, +congestion, sore throat, cough, shortness of breath, chest pain, +abdominal pain, nausea, vomiting, BRBPR, melena, hematochezia, +dysuria, hematuria. + +Past Medical History: +1. C4/C5 Spinal Cord Injury (17 y/a)due to MVA - can move arms +slightly cannot move legs +2. OSA on CPAP at home +3. Seizure Disorder ('[**62**]-'[**63**]) +4. Baclofen Pump ('[**49**], '[**54**], '[**61**]). Managed at [**Hospital1 2177**]. +5. s/p appendicovesicostomy +6. Multiple past urinary tract infections including w mild UAs +per [**Month (only) 116**] discharge summary, have included Klebsiella, ESBL E +coli, enterococcus. + +Social History: +Lives with roommates in house in [**Location (un) 620**], MA. Has private aides +to help with ADLs. Until recent seizures, drove himself using +modified car. Used to work at UPS in Marketing. Had MVA at age +17 resulting in quadriplegia. + +Family History: +Father had [**Name2 (NI) **] in 50s. + +Physical Exam: +Vitals - T:97.5 BP:98/56 HR:61 RR:16 02 sat:93RA +GENERAL: Pleasant, well appearing male, flat affect, NAD +HEENT: Normocephalic, atraumatic. No conjunctival pallor. No +scleral icterus. PERRLA/EOMI. MMM. OP clear. Neck Supple, No +LAD, No thyromegaly. Right eye prothesis +CARDIAC: Regular rhythm, normal rate. Normal S1, S2. No murmurs, +rubs or [**Last Name (un) 549**]. JVP flat. +LUNGS: Coarse breath sounds bilaterally. Good air movement. +ABDOMEN: NABS. Soft, NT, ND. No HSM +EXTREMITIES: No calf pain, 2+ edema to mid calf. 2+ dorsalis +pedis/ posterior tibial pulses. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Appropriate. CN 2-12 intact (right eye prothesis). +Preserved sensation throughout. 0/5 strength in LE bilaterally. +Delt [**2-26**] bilat. Biceps [**2-26**] bilat. Able to pronate and supinate +arms but not against resistance. 0/5 wrists, fingers and entire +lower extremities. +PSYCH: Listens and responds to questions appropriately, pleasant + + + +Pertinent Results: +[**2169-10-14**] +144 108 52 +------------ 60 +5.0 25 1.6 +. +.....8.6 +2.5 ----- 51 ∆ +.....25.3 +N:55.4 L:36.0 M:6.0 E:1.9 Bas:0.7 +. +PT: 12.3 PTT: 36.2 INR: 1.0 +. +Urine Analysis: Bld Lg Prot 25 RBC [**5-3**] WBC [**1-26**] +. +Discharge Labs: +145 110 25 +-------------- 75 +3.7 28 1.2 +. +Ca 8.3, Mg 1.8, Phos 2.6 +. +vanc trough 34.1 +[**10-15**] EEG: This is an abnormal portable EEG due to intermittent +left +mid to posterior temporal theta slowing that, at times, appears +monomorphic and more suspicious for epileptiform activity. These + +findings suggest possible subcortical dysfunction in this area. +Anatomic correlation is indicated. A repeat study with +sphenoidal +electrodes may be performed to help clarify the above findings. +. +[**10-15**] CXR: Bibasilar pneumonia. +. +[**10-15**] CT Head: +CONCLUSION: No definite sign of an intracranial hemorrhage. See +above report for requested potential prior outside studies and +their reports. + +COMMENT: Seen on the lateral scout radiograph are two screws +overlying the mid cervical spine and a possible intervening +wire. Please provide information as to whether this finding +constitutes some form of prior surgical treatment. At least the +more cephalad screw was likely visible on the prior sagittal +T1-weighted scans as an area of susceptibility. +CONCLUSION: No definite sign of an intracranial hemorrhage. See +above report for requested potential prior outside studies and +their reports. +COMMENT: Seen on the lateral scout radiograph are two screws +overlying the +mid cervical spine and a possible intervening wire. Please +provide +information as to whether this finding constitutes some form of +prior surgical treatment. At least the more cephalad screw was +likely visible on the prior sagittal T1-weighted scans as an +area of susceptibility. +. +[**10-17**] CXR (portable): Newly developed, slightly asymmetrical +pulmonary edema with new right pleural effusion, which is small +to moderately large +. +[**10-18**] MRI Head: 1. Motion artifact degrades image quality. +Areas of apparent T2 hyperintensity in the right temporal lobe +may be artifactual related to the patient motion. The parenchyma +is otherwise grossly unremarkable. If there is focal semiology +and further clinical concern, repeat MRI of the brain as per the +seizure protocol may be helpful if the patient is able to better +tolerate the procedure without movement. +2. Stable prosthesis in the right orbit. +3. Fluid within the right mastoid air cells and paranasal +sinuses, improved since the prior study. +. +[**10-18**] CXR: Previous mild pulmonary edema has resolved. +Opacification in the right lower lung and accompanied downward +displacement of the hilus indicates that previous area of +consolidation has now collapsed. Pulmonary edema has resolved +since [**10-17**]. Consolidation in the left lower lobe has +worsened since [**10-13**] and could be another region of +atelectasis or pneumonia. The upper lungs are now clear. Heart +size is normal. Pleural effusion, if any, is minimal. ET tube is +in standard placement. +. +[**10-19**] CXR: +The patient was extubated. There is a radiopaque object +projecting over the upper neck that is most likely external but +should be correlated clinically. Cardiomediastinal silhouette +is unchanged including minimal cardiomegaly. Compared to prior +study obtained yesterday at 08:26 a.m. there is significant +improvement in bibasal atelectasis and bilateral opacities +consistent with resolution of the atelectatic process and +decrease in pleural effusion. There is still present left +retrocardiac opacity that might represent infectious process or +residual atelectasis. No evidence of failure is present. + + +Brief Hospital Course: +39 yom with h/o C5 quadriplegia, MDS, and recurrent UTIs who was +transferred from OSH for assessment of altered mental status and +UTI. Hospital course was complicated by HAP and tonic clonic +seizures. +. +#Seizures/AMS: On [**2169-10-15**], pt had a generalized tonic clonic +seizure with hypoxia of 88% on RA. He was treated with IV ativan +and was subsequently post-ictal. He was placed on continuous +oxygen monitoring and on 4L nasal cannula. He was started on IV +Keppra 1000 mg [**Hospital1 **]. EEG showed left mid to posterior temporal +theta slowing. On [**2169-10-17**] he had a second generalized tonic +clonic seizure lasting one minute. He was given IV ativan and +subsequently noted to be hypoxic to 85% on 4L nasal cannula. +His respiratory rate was [**5-1**]/min with periods of apnea. He was +tranferred tot he MICU where he remained seizure free. It was +thought that the etiology of his seizure was infection +(multifocal pneumonia noted on CXR, sputum positive for G+ +cocci). Blood cultures, urine cultures, and cerebral spinal +fluid showed no growth. Head CT and MRI were negative for acute +process. Per neurology, he was treated with Keppra 1000mg [**Hospital1 **] +and loaded with dilantin. Both antiepileptics are to be +continued as outpatient per the neurology team. Dilantin levels +should be checked in one week. Dilantin can be tapered as +outpatient per Dr. [**Last Name (STitle) **]. + +#Hypoxia/Pneumonia: Patient was hypoxic and apneic post seizure +with evidence of multifocal pneumonia on CXR. He was intubated +to protect his airway and to allow him to have an LP and MRI. +He was extubated the following day, oxygen requirement reduced +until he was on room air when transferred from the MICU back to +the floor. He continued BiPap at night per his home regimen. +He was treated with vancomycin and aztreonam for his pneumonia. +Patient will be discharged home with IV vancomycin and aztreonam +to finish a 10d course. The last day of the antibiotics will be +[**2169-10-26**]. On the day of discharge, patient's vanc +trough was 34, so vancomycin was held. Critical care/infusion +company was instructed to draw vanc trough on the morning +post-discharge, and fax the result to Dr. [**Last Name (STitle) **], patient's PCP. +[**Last Name (NamePattern4) **].[**Name (NI) 2056**] office was [**Name (NI) 653**], and the RN was told that goal +vanc trough is 15-20. If trough > 20, continue to hold +vancomycin. If vanc < 20, restart vancomycin at 1gm [**Hospital1 **], and +then re-check vanc trough before the 4th dose. + +#Bradycardia: Pt has history of HR ranging from 38 to 70 while +in the MICU. He was found to be hypothermic and was warmed with +a bear hugger which improved his HR mildly. He did experience +some light headedness but no chest pain or shortness of breath. +EKG was unimpressive, cardiac enzymes showed mildly elevated +troponins which were consistent with past measurements. No +invasive measures were taken. He should be evaluated as +outpatient regarding possible intervention. + +# Elevated troponin: Patient found to have trop of 0.25 when +having bradycardic event. According to records, this seems to +be his baseline. Could be related to renal dysfunction. Has +had cardiology consulted in the past and no interventions were +recommended. No further actions taken. +. +#C5 spinal cord injury: Continued Baclofen pump. Physical +therapy found patient to be independent and able to live +independently. + +#Depression: Home Zoloft was continued. +. +#Chronic Kidney Disease: Baseline Creatinine 1.5-1.7. Received +gentle hydration, monitored urine output, renally dosed +medications, trended creatinine. Cr 1.2 on discharge. +. +#Hypernatremia: Could be due to dehydration in the setting of +sepsis. He was given D5 boluses in the MICU. He continued to +have fluctuating hypernatremia. He was encouraged to take more +fluids. His Na was 145 on discharge. +. +FEN: D5W boluses d/t hypernatremia, repleted electrolytes, +advanced to normal diet after extubation. +Prophylaxis: SC heparin +Access: discharged with PICC +Code: Full (discussed with patient) +Communication: Patient, Mother( HCP) [**Telephone/Fax (1) 49141**]; Brother [**Name (NI) **] +[**Telephone/Fax (1) 49142**] +Disposition: home with IV antibiotics and VNA service + + +Medications on Admission: +Medications (home - per OMR note): +-Keppra 500mg [**Hospital1 **] (recent dosing somewhat unclear, [**Name (NI) 620**] d/c +summary says 1000 mg [**Hospital1 **]) +-Trazodone 50 mg QHS: PRN +-Sertraline 100 mg daily +-B-Complex with Vitamin C Tablet Sig: One (1) Tablet PO +DAILY (Daily). +-Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +-Senna 8.6 mg Tablet Sig: 1-2 Tablets PO once a day. +-Baclofen 50 mcg/mL Solution Sig: Eighteen (18) mcg Intrathecal + +once a day +-Simvastatin 20mg PO daily +-Metronidazole 500mg [**Hospital1 **] [appears not to be taking] +. +. +MEDICATIONS (on transfer): +Phenytoin 200 mg IV QHS at 10pm +Phenytoin 100 mg IV BID at 7am and 2pm +Desonide 0.05% Cream 1 Appl TP [**Hospital1 **] +Fluocinolone Acetonide 0.01% Solution 1 Appl TP [**Hospital1 **] +Ketoconazole 2% 1 Appl TP [**Hospital1 **] +MetRONIDAZOLE (FLagyl) 500 mg IV Q8H, Day 1=[**10-18**] +Aztreonam [**2159**] mg IV Q8H [**10-17**] @ 1519 +Vancomycin 1000 mg IV Q 12H [**10-17**] @ 1135 +Bacitracin Ointment 1 Appl TP QID +Lorazepam 2 mg IV PRN seizure +LeVETiracetam 1000 mg IV Q12H +Baclofen 18 mcg/hr IT WITH PUMP +TraZODONE 50 mg PO/NG HS:PRN insomnia +Simvastatin 40 mg PO/NG DAILY +Acetaminophen [**Telephone/Fax (1) 1999**] mg PO/NG Q6H:PRN fever or pain +Senna 1 TAB PO/NG [**Hospital1 **]:PRN constipation +Sertraline 100 mg PO/NG DAILY +Heparin 5000 UNIT SC TID + +Discharge Medications: +1. Outpatient Lab Work +Vancomycin trough levels drawn on AM [**10-24**]. Results should be +faxed to [**First Name8 (NamePattern2) 30642**] [**Doctor Last Name **] [**Telephone/Fax (1) 36518**] +2. Sertraline 50 mg Tablet Sig: Two (2) Tablet PO DAILY (Daily). + +3. Senna 8.6 mg Tablet Sig: 1-2 Tablets PO BID (2 times a day). + +4. Levetiracetam 500 mg Tablet Sig: Two (2) Tablet PO Q12H +(every 12 hours). +5. Trazodone 50 mg Tablet Sig: One (1) Tablet PO at bedtime as +needed for insomnia. +6. B Complex Plus Vitamin C 15-10-50-5-300 mg Capsule Sig: One +(1) Capsule PO once a day. +7. Docusate Sodium 100 mg Capsule Sig: One (1) Capsule PO twice +a day. +8. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +9. Baclofen Intrathecal +10. Phenytoin Sodium Extended 100 mg Capsule Sig: One (1) +Capsule PO BID (2 times a day): 7AM and 2PM. +Disp:*60 Capsule(s)* Refills:*0* +11. Phenytoin Sodium Extended 100 mg Capsule Sig: Two (2) +Capsule PO QHS (once a day (at bedtime)): at 10PM. +12. Aztreonam in Dextrose(IsoOsm) 2 gram/50 mL Piggyback Sig: +Two (2) gram Intravenous Q8H (every 8 hours) for 3 days. +Disp:*18 gram* Refills:*0* +13. Vancomycin 1,000 mg Recon Soln Sig: One (1) gram Intravenous +every twelve (12) hours for 3 days: Please draw vanc trough in +the AM, fax it to Dr.[**Name (NI) 2056**] Office. Hold Vanc for trough. If +trough <20, give vanc 1gm q12h for 3 days. +Disp:*6 gram* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 119**] Homecare + +Discharge Diagnosis: +primary: hospital acquired pneumonia, urinary tract infection, +mental status change, and seizures, hypernatremia +secondary: chronic renal insufficiency. + + +Discharge Condition: +stable, afebrile. + + +Discharge Instructions: +You were admitted for evaluation after transfer from an outside +hospital for symptoms of mental status confusion in the setting +of a urinary tract infection. A CT scan at the outside hospital +showed a bleed in the head, but repeat imaging here showed no +evidence of bleed. During your hospitalization here, you were +found to have a pneumonia. You also developed seizures, which +you have not had in a long time. You were transferred to the +ICU for low oxygenation which after a day improved. You were +followed by neurology who adjusted your seizure medications. + +Medications changed during this hospitalizaiton include: +--> You were started on dilantin due to active seizures. You +will follow up with Dr. [**Last Name (STitle) **] to slowly stop taper off this +medication. +--> Please continue to take keppra for seizure prevention +--> You have three more days of IV antibiotics to treat +pneumonia. The last day of antibiotics will be [**2169-10-26**]. + +Pleae call your doctor or come to the Emergency Room if you +develop shortness of breath, seizures, chest pain, bleeding, +severe fatigue and weakness or any other symptom that concerns +you. + +Followup Instructions: +PCP: [**Last Name (NamePattern4) **]. [**First Name8 (NamePattern2) 30642**] [**Name (STitle) **], on Mon [**2169-11-6**] at 11:45am + +MD: Dr [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] +Specialty: Neurology +Date and time: Wednesday, [**11-8**] at 4pm +Location: [**Hospital Ward Name 516**], [**Hospital Ward Name 23**] bldg, [**Location (un) **] +Phone number: [**Telephone/Fax (1) 541**] + + + + +",47,2169-10-14 18:37:00,2169-10-23 19:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,ALTERED MENTAL STATUS," +39 yom with h/o c5 quadriplegia, mds, and recurrent utis who was +transferred from osh for assessment of altered mental status and +uti. hospital course was complicated by hap and tonic clonic +seizures. +. +#seizures/ams: on [**2169-10-15**], pt had a generalized tonic clonic +seizure with hypoxia of 88% on ra. he was treated with iv ativan +and was subsequently post-ictal. he was placed on continuous +oxygen monitoring and on 4l nasal cannula. he was started on iv +keppra 1000 mg [**hospital1 **]. eeg showed left mid to posterior temporal +theta slowing. on [**2169-10-17**] he had a second generalized tonic +clonic seizure lasting one minute. he was given iv ativan and +subsequently noted to be hypoxic to 85% on 4l nasal cannula. +his respiratory rate was [**5-1**]/min with periods of apnea. he was +tranferred tot he micu where he remained seizure free. it was +thought that the etiology of his seizure was infection +(multifocal pneumonia noted on cxr, sputum positive for g+ +cocci). blood cultures, urine cultures, and cerebral spinal +fluid showed no growth. head ct and mri were negative for acute +process. per neurology, he was treated with keppra 1000mg [**hospital1 **] +and loaded with dilantin. both antiepileptics are to be +continued as outpatient per the neurology team. dilantin levels +should be checked in one week. dilantin can be tapered as +outpatient per dr. [**last name (stitle) **]. + +#hypoxia/pneumonia: patient was hypoxic and apneic post seizure +with evidence of multifocal pneumonia on cxr. he was intubated +to protect his airway and to allow him to have an lp and mri. +he was extubated the following day, oxygen requirement reduced +until he was on room air when transferred from the micu back to +the floor. he continued bipap at night per his home regimen. +he was treated with vancomycin and aztreonam for his pneumonia. +patient will be discharged home with iv vancomycin and aztreonam +to finish a 10d course. the last day of the antibiotics will be +[**2169-10-26**]. on the day of discharge, patients vanc +trough was 34, so vancomycin was held. critical care/infusion +company was instructed to draw vanc trough on the morning +post-discharge, and fax the result to dr. [**last name (stitle) **], patients pcp. +[**last name (namepattern4) **].[**name (ni) 2056**] office was [**name (ni) 653**], and the rn was told that goal +vanc trough is 15-20. if trough > 20, continue to hold +vancomycin. if vanc < 20, restart vancomycin at 1gm [**hospital1 **], and +then re-check vanc trough before the 4th dose. + +#bradycardia: pt has history of hr ranging from 38 to 70 while +in the micu. he was found to be hypothermic and was warmed with +a bear hugger which improved his hr mildly. he did experience +some light headedness but no chest pain or shortness of breath. +ekg was unimpressive, cardiac enzymes showed mildly elevated +troponins which were consistent with past measurements. no +invasive measures were taken. he should be evaluated as +outpatient regarding possible intervention. + +# elevated troponin: patient found to have trop of 0.25 when +having bradycardic event. according to records, this seems to +be his baseline. could be related to renal dysfunction. has +had cardiology consulted in the past and no interventions were +recommended. no further actions taken. +. +#c5 spinal cord injury: continued baclofen pump. physical +therapy found patient to be independent and able to live +independently. + +#depression: home zoloft was continued. +. +#chronic kidney disease: baseline creatinine 1.5-1.7. received +gentle hydration, monitored urine output, renally dosed +medications, trended creatinine. cr 1.2 on discharge. +. +#hypernatremia: could be due to dehydration in the setting of +sepsis. he was given d5 boluses in the micu. he continued to +have fluctuating hypernatremia. he was encouraged to take more +fluids. his na was 145 on discharge. +. +fen: d5w boluses d/t hypernatremia, repleted electrolytes, +advanced to normal diet after extubation. +prophylaxis: sc heparin +access: discharged with picc +code: full (discussed with patient) +communication: patient, mother( hcp) [**telephone/fax (1) 49141**]; brother [**name (ni) **] +[**telephone/fax (1) 49142**] +disposition: home with iv antibiotics and vna service + + + ","PRIMARY: [Pneumonia, organism unspecified] +SECONDARY: [Quadriplegia, unspecified; Acute respiratory failure; Other encephalopathy; Acute kidney failure, unspecified; Urinary tract infection, site not specified; Generalized convulsive epilepsy, with intractable epilepsy; Hyperosmolality and/or hypernatremia; ; Late effect of spinal cord injury; Late effects of motor vehicle accident; Myelodysplastic syndrome, unspecified; Obstructive sleep apnea (adult)(pediatric); Other specified cardiac dysrhythmias; Depressive disorder, not elsewhere classified; Hyperpotassemia; Chronic kidney disease, Stage II (mild); Pressure ulcer, heel; Pressure ulcer, stage II]" +74562,138356.0,12886,2162-03-26,12885,116713.0,2162-03-13,Discharge summary,"Admission Date: [**2162-3-6**] Discharge Date: [**2162-3-13**] + +Date of Birth: [**2094-12-7**] Sex: M + +Service: NEUROLOGY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 618**] +Chief Complaint: +inability to speak or move right side + +Major Surgical or Invasive Procedure: +MRI/MRA +PEG +ECHO + +History of Present Illness: +Mr. [**Known lastname 39615**] is a 67-year-old right-handed man with a history +of CAD, hyperlipidemia, PAF not anticoagulated, and lung cancer +in remission who presents with acute onset aphemia and right +hemiplegia. +He was last seen normal at 10 pm last night by his daughter; his +wife had already gone to bed. When his wife awoke the next +morning, she found him at about 6 am lying face down on the +floor, unable to speak or move his right side. His daughter came +over, and thought he seemed sleepy, but noted he did look up at +her when she was there. EMS was called and brought him +immediately to [**Hospital1 18**] ED. + +NIH Stroke Scale score was 16: +1a. Level of Consciousness: 1 +1b. LOC Question: 2 +1c. LOC Commands: 0 +2. Best gaze: 0 +3. Visual fields: 0 +4. Facial palsy: 2 +5a. Motor arm, left: 0 +5b. Motor arm, right: 4 +6a. Motor leg, left: 0 +6b. Motor leg, right: 4 +7. Limb Ataxia: 0 +8. Sensory: 0 +9. Language: 3 +10. Dysarthria: UN +11. Extinction and Neglect: 0 + +Formal ROS is not possible. His daughter reports that last night +he was sitting on the edge of his bed apparently uncomfortable, +but did not complain of anything and otherwise was normal. + + +Past Medical History: +- CAD s/p MI and angioplasty [**2145**] +- Paroxysmal atrial fibrillation (per last cardiology note, ""he +has had atrial fibrillation when he gets acutely sick with COPD +flares with +pneumonias. However, he has been in sinus rhythm in the recent +past."") +- RUL SCLC s/p chemo and radiation [**2155**], in remission +- COPD +- Hyperlipidemia +- ""Probable DM"" + + +Social History: +Former heavy smoker, [**2-9**] ppd for 20-30 years, but quitin [**2155**] +years ago with lung cancer diagnosis. + + +Family History: +His mother died from a heart disease at the age of 75. +His father died from a throat cancer at the age of 52. + + +Physical Exam: +Vitals: T: 97.9 P: 88 reg R: 20 BP: 136/95 SaO2: 100%RA +General: Awake, cooperative, NAD. Labored breathing, with +significant upper airway sounds. +HEENT: NC/AT, no scleral icterus noted, MMM, no lesions noted in +oropharynx. +Neck: Hard collar in place. +Pulmonary: Loud upper airway sounds. +Cardiac: RRR, nl. S1S2, no M/R/G noted +Abdomen: obese. soft, NT/ND, normoactive bowel sounds, no masses +or organomegaly noted. +Extremities: No C/C/E bilaterally, 2+ radial, DP pulses +bilaterally. +Skin: no rashes or lesions noted. + +Neurologic: +-Mental Status: Awake and alert. No speech production. Follows +one-step commands, both appendicular and midline. Nods yes/no to +orientation questions appropriately. + +-Cranial Nerves: +I: Olfaction not tested. +II: PERRL 2.5 to 2mm and brisk. VFF to threat. Funduscopic exam +limited by miosis. +III, IV, VI: EOMI without nystagmus. Normal saccades. +V: Facial sensation intact to light touch. +VII: Partial right facial droop. +VIII: Hearing intact to finger-rub bilaterally. +IX, X: Palate elevates symmetrically. +[**Doctor First Name 81**]: 5/5 strength in trapezii and SCM bilaterally. +XII: Tongue protrudes in midline. + +-Motor: Normal bulk. Flaccid in right UE and LE. No pronator +drift on left. No adventitious movements, such as tremor, noted. +No asterixis noted. + + Delt Bic Tri WrE FFl FE IP Quad Ham TA Gastroc +L 5 5 5 5 5 5 5- 5 5- 5 5 +R 0 0 0 0 0 0 0 0 0 0 0 +Withdraws right LE to pain, no movement of R UE. + +-Sensory: Grossly, he nods that he can feel light touch +throughout. + +-DTRs: + [**Name2 (NI) **] Tri [**Last Name (un) 1035**] Pat Ach +L 2 2 2 2 1 +R 0 0 0 1 1 + +Plantar response was flexor bilaterally. + +-Coordination: Not tested on right. On left, no intention +tremor, +no dysdiadochokinesia noted. No dysmetria on FNF. + +-Gait: Unable due to right hemiplegia. + + +Pertinent Results: +[**2162-3-12**] 06:01AM BLOOD WBC-8.9 RBC-4.50* Hgb-14.4 Hct-41.5 +MCV-92 MCH-32.0 MCHC-34.7 RDW-13.2 Plt Ct-281 +[**2162-3-11**] 06:00AM BLOOD WBC-9.9 RBC-4.51* Hgb-14.7 Hct-41.7 +MCV-92 MCH-32.6* MCHC-35.3* RDW-13.3 Plt Ct-279 +[**2162-3-10**] 08:35AM BLOOD WBC-11.5* RBC-4.90 Hgb-15.2 Hct-45.5 +MCV-93 MCH-31.0 MCHC-33.3 RDW-13.6 Plt Ct-267 +[**2162-3-9**] 06:15AM BLOOD WBC-9.4 RBC-4.21* Hgb-14.1 Hct-38.6* +MCV-92 MCH-33.4* MCHC-36.5* RDW-12.9 Plt Ct-247 +[**2162-3-8**] 06:45AM BLOOD WBC-9.1 RBC-4.18* Hgb-13.6* Hct-38.2* +MCV-91 MCH-32.5* MCHC-35.6* RDW-13.1 Plt Ct-263 +[**2162-3-7**] 02:27AM BLOOD WBC-9.7 RBC-4.18* Hgb-13.7* Hct-37.9* +MCV-91 MCH-32.7* MCHC-36.1* RDW-13.1 Plt Ct-263 +[**2162-3-6**] 07:30AM BLOOD Neuts-79.6* Lymphs-13.4* Monos-5.7 +Eos-0.8 Baso-0.4 +[**2162-3-12**] 06:01AM BLOOD PT-15.9* PTT-27.1 INR(PT)-1.4* +[**2162-3-11**] 06:00AM BLOOD PT-16.1* PTT-26.3 INR(PT)-1.4* +[**2162-3-7**] 02:27AM BLOOD PT-16.6* PTT-28.4 INR(PT)-1.5* +[**2162-3-6**] 07:30AM BLOOD PT-16.0* PTT-28.1 INR(PT)-1.4* +[**2162-3-12**] 06:01AM BLOOD Glucose-138* UreaN-33* Creat-0.7 Na-142 +K-4.0 Cl-107 HCO3-26 AnGap-13 +[**2162-3-11**] 06:00AM BLOOD Glucose-132* UreaN-33* Creat-0.8 Na-140 +K-4.2 Cl-103 HCO3-27 AnGap-14 +[**2162-3-10**] 08:35AM BLOOD Glucose-173* UreaN-27* Creat-0.8 Na-137 +K-4.5 Cl-101 HCO3-28 AnGap-13 +[**2162-3-9**] 06:15AM BLOOD Glucose-204* UreaN-22* Creat-0.8 Na-137 +K-4.2 Cl-100 HCO3-27 AnGap-14 +[**2162-3-7**] 02:27AM BLOOD Glucose-165* UreaN-15 Creat-0.8 Na-136 +K-4.0 Cl-103 HCO3-24 AnGap-13 +[**2162-3-6**] 07:30AM BLOOD Glucose-246* UreaN-15 Creat-0.7 Na-135 +K-3.8 Cl-97 HCO3-26 AnGap-16 +[**2162-3-6**] 07:30AM BLOOD ALT-33 AST-40 CK(CPK)-234* AlkPhos-120* +TotBili-0.5 +[**2162-3-7**] 02:27AM BLOOD CK-MB-3 cTropnT-<0.01 +[**2162-3-12**] 06:01AM BLOOD Calcium-9.0 Phos-3.4 Mg-2.3 +[**2162-3-6**] 07:30AM BLOOD Albumin-4.4 Calcium-9.3 Phos-2.8 Mg-2.0 +[**2162-3-8**] 06:45AM BLOOD Triglyc-147 HDL-40 CHOL/HD-3.7 LDLcalc-80 +[**2162-3-6**] 07:30AM BLOOD ASA-NEG Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG + +CT HEAD: 1. Dense left middle cerebral artery with loss of +definition of insular region indicative of an evolving infarct. +2. Perfusion defect in the left middle cerebral artery territory +with increased transit time and decreased blood volume +suggestive of an evolving infarct. 3. CT angiography of the neck +demonstrates complete occlusion of the left +internal carotid artery in the neck with calcification at the +bifurcation. +60-70% stenosis of the right internal carotid artery is seen at +the +bifurcation. 4. CTA of the head demonstrates filling defect in +the left middle cerebral artery M1 segment with diminished flow +in the distal left MCA territory. + +MRI: Acute left sided basal ganglia and anterior MCA territory +infarcts. No hemorrhage. Clot in the middle cerebral artery +region. + +ECHO: Suboptimal image quality. Preserved left ventricular +systolic function. No intracardiac shunt with saline contrast +injected at rest (unable to cooperate with maneuvers). + + +Brief Hospital Course: +Pt was initially admitted to the neuro-ICU for observation +following his acute infarct. An MRI showed an acute infarct in +left MCA territory. This was likely cardio-embolic as he was +noted to be in A-fib upon admission. He was started on aspirin +but anticoagulation was not initiallly started because of the +size of the lesion and risk for hemorrhagic conversion. His +exam slowly improved and he became more alert. Despite being +more alert he failed multiple swallow evaluations and had a +g-tube placed on [**3-12**]. He was started on coumadin after the +g-tube was placed. He should stay on aspirin 81mg until his +coumadin becomes therapeutic (INR [**2-9**]). + +Medications on Admission: +ASA 325 mg po daily +Metoprolol 50 mg po bid +Simvastatin 10 mg po qhs +NTG SR 2.5 mg po bid +Atrovent 17 mcg 2 puffs qid +Albuterol 90 mcg 2 puffs q6h prn +Flovent 220 mcg 2 puffs [**Hospital1 **] +ProAir + + +Discharge Medications: +1. Acetaminophen 325 mg Tablet Sig: Two (2) Tablet PO Q6H (every +6 hours) as needed for temp > 100.4 or pain. +2. Docusate Sodium 50 mg/5 mL Liquid Sig: One (1) PO BID (2 +times a day). +3. Nitroglycerin 2.5 mg Capsule, Sustained Release Sig: One (1) +Capsule, Sustained Release PO Q12H (every 12 hours) as needed. +4. Ipratropium Bromide 0.02 % Solution Sig: One (1) Inhalation +Q6H (every 6 hours). +5. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed. +6. Famotidine 20 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day). +7. Warfarin 5 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM. +8. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +9. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for temp > 100.4 or pain. +10. Senna 8.6 mg Tablet Sig: One (1) Tablet PO BID (2 times a +day) as needed. +11. Docusate Sodium 50 mg/5 mL Liquid Sig: One (1) PO BID (2 +times a day). +12. Nitroglycerin 2.5 mg Capsule, Sustained Release Sig: One (1) +Capsule, Sustained Release PO Q12H (every 12 hours) as needed. +13. Fluticasone 110 mcg/Actuation Aerosol Sig: Four (4) Puff +Inhalation [**Hospital1 **] (2 times a day). +14. Ipratropium Bromide 0.02 % Solution Sig: One (1) Inhalation +Q6H (every 6 hours). +15. Albuterol Sulfate 2.5 mg /3 mL (0.083 %) Solution for +Nebulization Sig: One (1) Inhalation Q6H (every 6 hours) as +needed. +16. Simvastatin 40 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +17. Famotidine 20 mg Tablet Sig: One (1) Tablet PO BID (2 times +a day). +18. Warfarin 5 mg Tablet Sig: One (1) Tablet PO Once Daily at 4 +PM. +19. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +20. Heparin (Porcine) 5,000 unit/mL Solution Sig: One (1) ml +Injection TID (3 times a day). + + +Discharge Disposition: +Extended Care + +Facility: +[**Hospital6 85**] - [**Location (un) 86**] + +Discharge Diagnosis: +Left MCA Infarct +AFIB + + +Discharge Condition: +Right hemiparesis, global aphasia + + +Discharge Instructions: +You were admitted for right sided weakness and difficulty +speaking. This was caused by a stroke which was likley due to a +blood clot from your heart. You will need to take coumadin to +prevent blood clots in the future. + +Followup Instructions: +Provider: [**Name10 (NameIs) **] SCAN Phone:[**Telephone/Fax (1) 327**] Date/Time:[**2162-4-12**] 9:45 +Provider: [**Name10 (NameIs) 1571**] FUNCTION LAB Phone:[**Telephone/Fax (1) 609**] +Date/Time:[**2162-4-22**] 9:10 +Provider: [**First Name11 (Name Pattern1) 1569**] [**Initials (NamePattern4) **] [**Last Name (NamePattern4) **], M.D. Phone:[**Telephone/Fax (1) 612**] +Date/Time:[**2162-4-22**] 9:30 +Dr. [**Last Name (STitle) **] - Call [**Telephone/Fax (1) 44**] for appointment info + + + [**Name6 (MD) **] [**Name8 (MD) **] MD, [**MD Number(3) 632**] + +",13,2162-03-06 09:37:00,2162-03-13 14:15:00,EMERGENCY,EMERGENCY ROOM ADMIT,REHAB/DISTINCT PART HOSP,STROKE;TELEMETRY;TRANSIENT ISCHEMIC ATTACK," +pt was initially admitted to the neuro-icu for observation +following his acute infarct. an mri showed an acute infarct in +left mca territory. this was likely cardio-embolic as he was +noted to be in a-fib upon admission. he was started on aspirin +but anticoagulation was not initiallly started because of the +size of the lesion and risk for hemorrhagic conversion. his +exam slowly improved and he became more alert. despite being +more alert he failed multiple swallow evaluations and had a +g-tube placed on [**3-12**]. he was started on coumadin after the +g-tube was placed. he should stay on aspirin 81mg until his +coumadin becomes therapeutic (inr [**2-9**]). + + ","PRIMARY: [Cerebral embolism with cerebral infarction] +SECONDARY: [Chronic airway obstruction, not elsewhere classified; Dysphagia, unspecified; Coronary atherosclerosis of native coronary artery; Other and unspecified hyperlipidemia; Atrial fibrillation; Personal history of malignant neoplasm of bronchus and lung; Pure hypercholesterolemia; Personal history of tobacco use; Diabetes mellitus without mention of complication, type II or unspecified type, not stated as uncontrolled; Unspecified essential hypertension]" +74674,160180.0,12815,2176-10-29,12814,194853.0,2176-10-11,Discharge summary,"Admission Date: [**2176-10-5**] Discharge Date: [**2176-10-11**] + +Date of Birth: [**2098-7-21**] Sex: M + +Service: MEDICINE + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 425**] +Chief Complaint: +chest pain, wide complex tachycardia + +Major Surgical or Invasive Procedure: +Internal Cardiac Defibrillator placement +cardiac catheterization + + +History of Present Illness: +78 y/o gentleman with chronic AF, known CAD--NSTEMI in [**8-28**] (3 x +13 mm Cypher to RPLV and 2.25 x 18 mm Cypher to LCx/OM; also +found to have 3-% LMCA, 70% mLAD with an 80% D1 and 90% D2), +repeat PCI in [**10-29**] with BMS to mid-LAD for 70% stenotic lesion, +possible ISR in [**2174**] with DES to LAD ([**Hospital1 3278**]), AS with most +recent estimate of [**Location (un) 109**] of 1.07 cm2, presents from [**Hospital1 **] ED where he was found to have an irregular wide-complex +tachycardia associated with chest pain. +. +The patient has a history of chronic stable angina, class II +Canadian Classification, able to walk about 1 mile or 1 flight +of stairs before angina and SOB. Was in USOH when at 8PM +tonight noted anginal equivalent only increased in intensity +(SSCP radiating to L arm). Took 3 SL NTG without relief. Taken +to [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] where found to have Wide-complex tachycardia. +Given Morphine IV, metoprolol IV 5mg x 2, Amiodarone 150mg IV x +1, and started on a diltiazem bolus 20 mg and 5mg/hr gtt. +Rhythm appeared to convert to sinus when he was loaded on +stretcher for EMS and symptoms resolved. Since then has had no +further episodes of AF and no further CP or SOB. Of note, he +stopped Plavix 6 months ago at the advice of his cardiologist. +. +In [**Hospital1 18**] ED his vitals were T 98.6 HR 61 BP 97/40 RR 25 87% +RA-> 100 % in NRB. Patient recieved 600 mg plavix x 1. His BP +occasionally dropes to SBP of 80s which improved to 110s with +500cc of NS. +. +On arrival to CCU, patient was asymptomatic. +. +ROS was negative for fever, chills, abdominal pain, recent +BRBPR, melena, dysuria, hematuri. Cough recently which patient +attributes to allergies. On cardiac review of symptoms, in +addition to above, patient notes stable 2 pillow orthopnea, no +PND or claudication. +Occasional RLE edema. All other review systems were negative. +. + +Past Medical History: +1. CARDIAC RISK FACTORS: - Diabetes, + Dyslipidemia, + +Hypertension +2. CARDIAC HISTORY: +-> CAD: NSTEMI [**2172**] PCI- DES of the r-PLV and LCx/OM, [**10-29**] PCI- +BMS +to LAD; [**2174**]- PCI ([**Hospital1 3278**]) [**Name Prefix (Prefixes) **]-[**Last Name (Prefixes) **] for possible ISR +-> Aortic Stenosis ([**Location (un) 109**] 1.07, mean Grad 21 mmHg), EF 50% on ETT +[**2172**] +-> Atrial Fibrillation +3. OTHER PAST MEDICAL HISTORY: +[**2172**]- CVA with residual speech difficulties +Anemia +GIB +Anxiety +Appendectomy +Right Inguinal hernia + +Social History: +Married with 1 adult son. [**Name (NI) **] is retired. Prior to retiring he +was a construction worker. Quit smoking 30 years ago. Prior to +quitting he smoked <1ppd for approximately 20-25 years. Denies +drinking alcoholic beverages or recreational drug use. + +Family History: +Father died of a myocardial infarction in his early 70's. His +sister underwent a CABG and died from a CVA at the age of 78. +His brother died of a myocardial infarction at the age of 39. + +Physical Exam: +Gen: Pleasant, in NAD, able to follow commands +HEENT: No conjunctival pallor. No icterus. MMM. OP clear. +NECK: Supple, No LAD. JVP 12 cm. Normal carotid upstroke without +bruits. +CV: Soft S1S2, Irregluarlary irregular. II/VI systolic murmur +best at USB. Early diastolic murmur. +LUNGS: Bibasilar crackles. +ABD: Soft, NT, ND. No HSM. Abdominal aorta was not enlarged by +palpation. Abdominal bruit is present. +EXT: 1+ edema BL. Full distal pulses bilaterally. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Grossly intact, no focal deficits. + +Discharge exam: +97.3 111/61 72 96% RA +HEENT: No conjunctival pallor. No icterus. MMM. OP clear. +NECK: Supple, No LAD. JVP 12 cm. Normal carotid upstroke without +bruits. +CV: Soft S1S2, Irregluarlary irregular. II/VI systolic murmur +best at USB. Early diastolic murmur. +LUNGS: CTA. +ABD: Soft, NT, ND. No HSM. Abdominal aorta was not enlarged by +palpation. Abdominal bruit is present. +EXT: 1+ edema BL. Full distal pulses bilaterally. +SKIN: No rashes/lesions, ecchymoses. +NEURO: A&Ox3. Grossly intact, no focal deficits. + +Pertinent Results: +LABS ON ADMISSION: +[**2176-10-5**] 12:00AM WBC-13.5*# RBC-4.01* HGB-12.2* HCT-37.7* +MCV-94# MCH-30.5 MCHC-32.5 RDW-14.0 +[**2176-10-5**] 12:00AM NEUTS-88.4* LYMPHS-8.0* MONOS-2.5 EOS-0.6 +BASOS-0.5 +[**2176-10-5**] 12:00AM PLT COUNT-127* +[**2176-10-5**] 12:00AM PT-27.5* PTT-32.9 INR(PT)-2.7* +[**2176-10-5**] 12:00AM CK-MB-8 +[**2176-10-5**] 12:00AM cTropnT-0.05* +[**2176-10-5**] 12:00AM CK(CPK)-118 +[**2176-10-5**] 12:00AM GLUCOSE-122* UREA N-29* CREAT-1.3* SODIUM-137 +POTASSIUM-4.9 CHLORIDE-105 TOTAL CO2-25 ANION GAP-12 +[**2176-10-5**] 04:49AM %HbA1c-5.6 +[**2176-10-5**] 04:49AM CK-MB-30* MB INDX-9.6* cTropnT-0.59* +[**2176-10-5**] 04:49AM CK(CPK)-313* +[**2176-10-5**] 01:02PM CK-MB-34* MB INDX-11.1* cTropnT-0.71* +[**2176-10-5**] 01:02PM CK(CPK)-306* +. +ECHO [**2176-10-5**]: The left atrium is dilated. There is mild +symmetric left ventricular hypertrophy. The left ventricular +cavity is moderately dilated. Overall left ventricular systolic +function is moderately depressed (LVEF= 30-40 %) secondary to +akinesis of the basal septum and hypokinesis of the rest of the +left ventricle. There is considerable beat-tobeat variability of +the left ventricular ejection fraction due to an irregular +rhythm. Tissue Doppler imaging suggests an increased left +ventricular filling pressure (PCWP>18mmHg). Right ventricular +chamber size and free wall motion are normal. The aortic root is +moderately dilated at the sinus level. The ascending aorta is +moderately dilated. The aortic valve leaflets are severely +thickened/deformed. There is moderate aortic valve stenosis +(valve area 1.0-1.2cm2). Moderate (2+) aortic regurgitation is +seen. The mitral valve leaflets are mildly thickened. There is +no mitral valve prolapse. Mild to moderate ([**1-26**]+) mitral +regurgitation is seen. +. +CARDIAC CATHETERIZATION [**2176-10-7**]: +1. Coronary angiography in this right dominant system revealed +diffuse calcified coronary artery disease. The LMCA had mild +disease. The LAD had widely patent stents, and total occlusion +of a moderate sized diagonal seen on prior catheterization from +[**2173-11-11**]. The distal 70% stenosis of the LAD was unchanged +versus prior. The LCX had a widely patent stent, and mild +luminal irregularities. The RCA was a large vessel, with +moderate calcification and serial 40-50% stenoses. There was a +large RPL that had a 60% stenosis in the mid-vessel, which was +unchanged compared with prior. +2. Resting hemodynamics revealed moderate-to-severe aortic +stenosis with mean gradient of 18 mmHg and estimated aortic +valve area of 1.0 cm2. There were elevated left and right-sided +filling pressures with mean RA pressure of 15, mean PCWP of 35 +mmHg, and LVEDP of 29 mmHg. Cardiac output was mildly depressed +at 4.0 L/min. +. +ABDOMINAL ULTRASOUND [**2176-10-7**]: +1. Atherosclerotic aorta with AAA measuring 4.1 cm at the widest +diameter. Slight interval increase from the ultrasound of +[**2173-10-24**]. +2. No hydronephrosis. Bilateral renal cysts. +3. No evidence of renal artery stenosis. +. +LABS ON DISCHARGE: +WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +7.9 3.88* 11.8* 35.4* 91 30.5 33.4 14.2 150 +. +Glucose UreaN Creat Na K Cl HCO3 AnGap +106* 20 0.9 134 4.0 101 26 11 +. +PT PTT INR(PT) +14.4* 28.6 1.2* + +Brief Hospital Course: +78 year old gentleman with coronary artery disease with PCI in +[**2174**], hypertension, moderate aortic stenosis, atrial +fibrillation, presented with rest angina in the setting of rapid +heart rate with wide complex tachycardia. +. +# CORONARIES: Presenting chest pain was concerning for unstable +angina. Known CAD as above. Cardiac enzymes were cycled with +peak trop at 0.92, MB 34, CK 313. Diagnostic left heart cath +showed patent coronaries with prior stents in place, no evidence +of renal artery stenosis. Pt received heparin drip during +hospitalization, as coumadin was held in anticipation of +procedures. Aspirin and plavix were started and continued at +discharge. HbA1c and lipid panel as above, all normal. Statin +was continued in house and at discharge, along with ACE +inhibitor, beta blockade, aspirin and plavix. +. +# RHYTHM: Episodes of wide complex tachycardia concerning for +ventricular tachycardia, orginating from left ventricular or +right ventricular outflow tract. Electrophysiology +study/intervention deferred in setting of highly calcific aorta +and moderate aortic stenosis. Initial rate control with +metoprolol. Sotalol was then started, monitored for QT +prolongation. Patient then remained in persistent atrial +fibrillation. Sotalol was continued, along with heparin gtt. +Patient had ICD placed on [**2176-10-10**], tolerated procedure well. +Metoprolol started after ICD was place. Warfarin was started +one day prior to discharge. INR had been therapeutic for at +least one month prior to admission. INR 1.2 on discharge, will +recheck INR in three days. +. +# PUMP: Known moderate/severe aortic stenosis in our system and +currently on exam. Cath in [**2173**] with aortic valve area of 1.07 +with gradient of 21 mmHg. Transthoracic echo as above. Imdur +was added to lisinopril, metoprolol, sotalol on discharge. +. +# Abdominal aortic aneurysm: Abdominal ultrasound showed AAA +measuring 4.1 cm at the widest diameter, slight interval +increase from the ultrasound of [**2173-10-24**]. +. +# ARF: Creatinine 1.3 on admission. Last Creatinine in our +system is 0.9 in [**2173**]. +Renal function improved over course of stay, 0.9 on discharge. +. +CODE: FULL +. +COMM: With patient and Wife, [**Name (NI) 39471**], [**Telephone/Fax (1) 39472**] + +Medications on Admission: +Aspirin 325mg daily +Metoprolol tartrate 75 mg [**Hospital1 **] +Simvastatin 80 mg qdaily +Warfarin 2mg for 2 days, then 1 mg next day, then repeat +Isosorbide dinitrate 10 mg tid +Lisinopril 5 mg qdaily +Nitroglycerin 0.4 SL prn + +Discharge Medications: +1. Aspirin 81 mg Tablet Sig: One (1) Tablet PO once a day. +2. Clopidogrel 75 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +Disp:*30 Tablet(s)* Refills:*2* +3. Simvastatin 80 mg Tablet Sig: One (1) Tablet PO once a day. +4. Lisinopril 5 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +5. Sotalol 80 mg Tablet Sig: 1.5 Tablets PO BID (2 times a day). +Disp:*90 Tablet(s)* Refills:*2* +6. Imdur 30 mg Tablet Sustained Release 24 hr Sig: One (1) +Tablet Sustained Release 24 hr PO once a day. +Disp:*30 Tablet Sustained Release 24 hr(s)* Refills:*2* +7. Warfarin 2 mg Tablet Sig: One (1) Tablet PO once a day: one +half tablet every third day. +8. Metoprolol Succinate Oral +9. Nitroglycerin 0.4 mg Tablet, Sublingual Sig: One (1) tablet +Sublingual as directed as needed for chest pain. +10. Outpatient Lab Work +Please check INR on Monday [**10-14**] and call results to Dr. [**Last Name (STitle) **] at +[**Telephone/Fax (1) 719**]. +11. Acetaminophen 325 mg Tablet Sig: 1-2 Tablets PO Q6H (every 6 +hours) as needed for pain. +Disp:*6 vils* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Location (un) 86**] VNA + +Discharge Diagnosis: +Ventricular Tachycardia +Non ST elevation Myocardial Infarction + + +Discharge Condition: +stable. + + +Discharge Instructions: +You had a dangerous heart rhythm called ventricular tachycardia +and was started on sotolol, a medicine to prevent this rhythm. +In addition, an internal defibrillator (ICD) was placed that +will shock you out of this rhythm. You cannot get the ICD +dressing wet for one week. No showers of baths. You may wash +your hair in a sink. You are scheduled in the device clinic in 1 +week, they will check the function of the ICD and take off the +dressing. No lifting more than 5 pounds with your left arm for 6 +weeks, no lifting your left arm over your head for 6 weeks. You +will be on antibiotics to prevent an infection at the ICD site +for 3 days. You also had a cardiac catheterization that showed +extensive blockages in your coronary artery. Your medicines were +adjusted to help your heart function. +Medication changes: +1. Sotolol: to prevent ventricular tachycardia +2. Restart your coumadin at 2 mg, you will need to check your +INR on Monday [**10-14**]. +3. Decrease your aspirin to 81mg, continue taking plavix. +. +Please call Dr. [**Last Name (STitle) **] if your ICD fires, if you have any +redness, swelling, tenderness or bleeding at the ICD site, if +you have any chest pain, fevers, chills or trouble breathing. +Weigh yourself every morning, [**Name8 (MD) 138**] MD if weight > 3 lbs in 1 day +or 6 pounds in 3 days. +Adhere to 2 gm sodium diet: information was given to you about +this at discharge. +. + + +Followup Instructions: +Cardiology: +Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] Phone: [**Telephone/Fax (1) 62**] Date/time: He will see +you during the device clinic appt. +Device Clinic: [**Hospital Ward Name 23**] [**Location (un) 436**], [**Hospital1 18**], [**Hospital Ward Name 516**], [**Location (un) **] [**Location (un) 86**]: Date/Time: [**2176-10-18**] 3:00pm +. +Primary Care: +Dr. [**First Name8 (NamePattern2) **] [**Last Name (NamePattern1) **] and Dr. [**First Name4 (NamePattern1) **] [**Last Name (NamePattern1) **] Phone: [**Last Name (NamePattern1) 39473**], [**Location (un) 86**] Date/time: [**11-6**] at 1:30pm. +. + + + +",18,2176-10-05 02:32:00,2176-10-11 18:00:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME HEALTH CARE,CHEST PAIN," +78 year old gentleman with coronary artery disease with pci in +[**2174**], hypertension, moderate aortic stenosis, atrial +fibrillation, presented with rest angina in the setting of rapid +heart rate with wide complex tachycardia. +. +# coronaries: presenting chest pain was concerning for unstable +angina. known cad as above. cardiac enzymes were cycled with +peak trop at 0.92, mb 34, ck 313. diagnostic left heart cath +showed patent coronaries with prior stents in place, no evidence +of renal artery stenosis. pt received heparin drip during +hospitalization, as coumadin was held in anticipation of +procedures. aspirin and plavix were started and continued at +discharge. hba1c and lipid panel as above, all normal. statin +was continued in house and at discharge, along with ace +inhibitor, beta blockade, aspirin and plavix. +. +# rhythm: episodes of wide complex tachycardia concerning for +ventricular tachycardia, orginating from left ventricular or +right ventricular outflow tract. electrophysiology +study/intervention deferred in setting of highly calcific aorta +and moderate aortic stenosis. initial rate control with +metoprolol. sotalol was then started, monitored for qt +prolongation. patient then remained in persistent atrial +fibrillation. sotalol was continued, along with heparin gtt. +patient had icd placed on [**2176-10-10**], tolerated procedure well. +metoprolol started after icd was place. warfarin was started +one day prior to discharge. inr had been therapeutic for at +least one month prior to admission. inr 1.2 on discharge, will +recheck inr in three days. +. +# pump: known moderate/severe aortic stenosis in our system and +currently on exam. cath in [**2173**] with aortic valve area of 1.07 +with gradient of 21 mmhg. transthoracic echo as above. imdur +was added to lisinopril, metoprolol, sotalol on discharge. +. +# abdominal aortic aneurysm: abdominal ultrasound showed aaa +measuring 4.1 cm at the widest diameter, slight interval +increase from the ultrasound of [**2173-10-24**]. +. +# arf: creatinine 1.3 on admission. last creatinine in our +system is 0.9 in [**2173**]. +renal function improved over course of stay, 0.9 on discharge. +. +code: full +. +comm: with patient and wife, [**name (ni) 39471**], [**telephone/fax (1) 39472**] + + ","PRIMARY: [Subendocardial infarction, initial episode of care] +SECONDARY: [Acute kidney failure, unspecified; Paroxysmal ventricular tachycardia; Acute on chronic systolic heart failure; Congestive heart failure, unspecified; Atrial fibrillation; Coronary atherosclerosis of native coronary artery; Other and unspecified angina pectoris; Unspecified essential hypertension; Other and unspecified hyperlipidemia; Anemia, unspecified; Anxiety state, unspecified; Aortic valve disorders; Atherosclerosis of aorta; Abdominal aneurysm without mention of rupture]" +75420,151414.0,8209,2190-10-22,8208,114387.0,2190-10-10,Discharge summary,"Admission Date: [**2190-10-8**] Discharge Date: [**2190-10-10**] + +Date of Birth: [**2123-7-4**] Sex: F + +Service: MEDICINE + +Allergies: +Paxil / Benadryl / Buspar / Levaquin / Adhesive Tape + +Attending:[**First Name3 (LF) 425**] +Chief Complaint: +Pericardial effusion s/p SVT ablation + +Major Surgical or Invasive Procedure: +electrophysiology study with incomplete ablation + + +History of Present Illness: +66-year-old lady with history of breast and bladder cancers was +admitted for elective EPS with ablation for SVT. She first +noted palpitations approximately 16 years ago in the setting of +high emotional distress when her son was killed while in the +service. Since then, she has had palpitations in the setting of +chemotherapy, and over the past years has had no more than [**3-2**] +episodes per year. However, on the day of her most recent +cystoscopy on [**3-5**] at [**Hospital1 69**], she +experienced a tachycardia, which was terminated after she +received intravenous Lopressor. The same tachycardia occurred on +[**3-9**] for which she presented to [**Hospital6 17032**] +Emergency Room, where the tachycardia was terminated with +intravenous adenosine. The tracings of the tachycardia were +reviewed by her Electrophysiologist, Dr.[**Last Name (STitle) 1911**], and +thought be a narrow complex tachycardia at 150 beats/minute with +an RP interval of 100-120 msec. However, immediately post +adenosine, there was evidence of sinus rhythm with a fully +pre-excited QRS complex consistent with a left lateral bypass +tract. Since the Emergency Room visit, she has been on low-dose +atenolol without further recurrences of the arrhythmia. +Dr.[**Last Name (STitle) 26676**] recommended EPS with ablation and the patient +was admitted today for the procedure. +. +During the procedure she developed hypotension to SBP of 77 mm +HG. This responded to IVF and dopamine infusion to SBP of 130s. + Patient was mentating appropriately. Focal views of TTE showed +noncircumferential pericardial effusion with mild RA collapse +without RV collapse. Her heparin was reversed with protamine. +PA catheterization showed preserved CO, no equalization of +filling pressures, and preserved Y descent on RA tracing. This +suggested nonhemodynamically significant effusion. Patient was +admitted to CCU with PA catheter for close hemodynamic +monitoring. +. +On arrival patient complained of stable pleuritic chest pain +which she had since the cath lab. She denied any shortness of +breath. No other complaints. +. + +Past Medical History: +1. CARDIAC RISK FACTORS: - Diabetes, + Dyslipidemia, - +Hypertension +2. CARDIAC HISTORY: +-CABG: N/A +-PERCUTANEOUS CORONARY INTERVENTIONS: N/A +-PACING/ICD: N/A +3. OTHER PAST MEDICAL HISTORY: +- Total abdominal hysterectomy and salpingoophrectomy [**2164**] r/t +endometriosis +- Left breast cancer diagnosed [**2180**] s/p Left lumpectomy and +radiation therapy +- Papillary bladder cancer diagnosed [**2180**] s/p multiple +resections +and chemotherapy, finished [**2190-4-28**] +- [**2190-3-5**] s/p right ureteral stent, ? transitional cell cancer +of +the right ureteral orifice +- Anxiety +. + +Social History: +Lives with: husband +Occupation: retired +ETOH: no +Tobacco: 35 years/ 1ppd, quit in [**2180**] +Contact person upon discharge: Husband and son: [**Telephone/Fax (1) 29176**] +Home Services: NO +. + +Family History: +Unremarkable for any cardiac disease +. + +Physical Exam: +VS: T=96 BP=103/58 HR=97 RR=17O2 sat= 98% 2LNC +GENERAL: Pleasant lady, in NAD. Lying down flat, Oriented x3. +Mood, affect appropriate. +HEENT: NCAT. Sclera anicteric. EOMI. Conjunctiva were pink, no +pallor or cyanosis of the oral mucosa. No xanthalesma. +NECK: Unable to assess JVP appropriately given the patient's +position. +CARDIAC: RR, normal S1, S2. No m/r/g. No thrills, lifts. No S3 +or S4. +LUNGS: Resp were unlabored, no accessory muscle use. CTAB in +anterior lung fields, no crackles, wheezes or rhonchi. +ABDOMEN: Soft, NTND. No HSM or tenderness. Abd aorta not +enlarged by palpation. +EXTREMITIES: No c/c/e. +SKIN: No stasis dermatitis. +PULSES: +Right: DP 2+ Left: DP 2+ +. + + +Pertinent Results: +[**2190-10-10**] 08:50AM BLOOD WBC-14.1* RBC-3.54* Hgb-9.5* Hct-30.5* +MCV-86 MCH-27.0 MCHC-31.3 RDW-14.7 Plt Ct-156 +[**2190-10-10**] 08:50AM BLOOD Glucose-120* UreaN-11 Creat-0.8 Na-135 +K-4.3 Cl-101 HCO3-26 AnGap-12 +[**2190-10-10**] 08:50AM BLOOD Calcium-8.6 Phos-1.6* Mg-2.5 +. +ECG: [**2190-10-8**] at 7:23 AM +NSR, rate in 70s, nl axis, early R wave transition in precordial +leads, no acute ST-T changes compared to +. +ECG: [**2190-10-8**] at 11:58 AM +Narrow complex tachycardia, rate in 140s, early R wave +transition. No acute ST-T wave changes. +. +2D-ECHOCARDIOGRAM [**2190-10-8**] Focused Views: +Left ventricular wall thickness, cavity size and regional/global +systolic function are normal (LVEF >55%). Right ventricular +chamber size and free wall motion are normal. There is a small +to moderate sized pericardial effusion primarily around the +right atrium and right ventricle with minimal around the apex +and inferolateral wall. There is mild right ventricular +diastolic collapse. +IMPRESSION: Mild-moderate loculated anterior pericardial +effusion with echocardiographic evidence for increased +pericardial pressure. +. +2D-ECHOCARDIOGRAM [**2190-10-9**] +The left ventricular cavity is unusually small. The inferior and +posterior walls are hypokinetic. The rest of the left ventricle +is hyperdynamic. Right ventricular chamber size and free wall +motion are normal. The aortic valve leaflets (3) are mildly +thickened but aortic stenosis is not present. The mitral valve +leaflets are mildly thickened. There is no mitral valve +prolapse. Trivial mitral regurgitation is seen. There is a small +to moderate sized pericardial effusion. The effusion appears +circumferential. There are no echocardiographic signs of +tamponade. No right atrial or right ventricular diastolic +collapse is seen. + +Compared with the findings of the prior study (images reviewed) +of [**2190-10-8**], the pericardial effusion appears similar +in size. +. +HEMODYNAMICS: +RAP 20, PCWP 17, Arterial oxygen 98%, RV oxygen sat 71% +. +EPS [**2190-10-8**]: +Left lateral ventricular pre-excitation. Retrograde VA block +via BT at 350 msec. Anterograde BT block at 300 msec. Atypical +Induced orthodromic AVRT, CL 400 msec via left lateral BT. +Difficulty crossing AV. Ablations were performed primarily at +the entrent atrial acitivation site during Vpacing. Also slow +pathway ablation were performed to prevent initiation of the +AVRT. Ablation procedure was incomplete given hypotension as +above. +. +CT ABDOMEN/PELVIS [**2190-10-9**]: +1. No retroperitoneal bleed. +2. Mild to moderate sized pericardial effusion with +indeterminate density +measurements suggesting proteinaceous fluid or blood. No obvious +right atrial compression. Recommend echocardiogram +3. Right femoral line with tip located at the cavoatrial +junction. +4. Left lobe hepatic cyst; could consider outpatient ultrasound +for further +characterization. +5. No large hematoma at right femoral entry site. +6. Stranding in mesentery, nonspecific finding. + + +Brief Hospital Course: +66 y/o lady with history of SVT now with pericardial effusion +s/p attempted EP ablation. +. +# Pericardial Effusion/PUMP: Patient was found to have a 1.4 cm +anterior pericardial effusion after she became hypotensive +during SVT ablation procedure on [**2190-10-8**]. TTE also showed mild +RA collapse without any RV collapse. Emergently, patient +received a right heart cath that was consistent with a +non-hemodynamically signicant effusion w/o tamponade physiology, +so pericardiocentesis was not felt to be indicated. (Cardiac +output was preserved and there was no equalization of filling +pressures.) Swan-ganz was initially left in place to monitor for +development of tamponade physiology. Arterial line was also +placed for blood pressure monitoring. Patient was initially +hypotensive, but her blood pressure was responsive to IV fluid +hydration and dopamine. Her blood pressure remained stable over +the next 24 hours, and a repeat TTE on [**10-9**] did not show +worsening of the pericardial effusion. Chest pain secondary to +the pericardial effusion was well-controlled with Toradol and +patient was discharged on ibuprofen prn for pain. +. +# RHYTHM: Prior to admission, SVT was thought be a narrow +complex tachycardia at 150 beats/minute with an RP interval of +100-120 msec. However, immediately post adenosine, there was +evidence of sinus rhythm with a fully pre-excited QRS complex +consistent with a left lateral bypass tract. In EP lab, +monitors showed left lateral ventricular pre-excitation, +retrograde VA block via BT at 350 msec, anterograde BT block +at 300 msec, and atypical induced orthodromic AVRT, CL 400 msec +via left lateral BT. During the procedure, it was difficult +crossing the AV, and ablations were performed primarily at the +entrent atrial acitivation site during Vpacing. Also slow +pathway ablation was performed to prevent initiation of the +AVRT. The ablation procedure was incomplete given hypotension +as above. Rhythm was monitored on telemetry and showed +predominantly sinus rhythm. +. +# CORONARIES: Patient has no known CAD. Chest pain while +inpatient was pleuritic in nature and attributed to +hemopericardium. ASA was continued. +. +# Extensive groin manipulation: Due to extensive groin +manipulation during cardiac procedures on [**2190-10-8**], patient was +monitored closely for evidence of retroperitoneal bleed. In the +cath lab, heparin was reversed with protamine, post cath checks +were unremarkable, and a CT scan of abdomen and pelvis was +negative for a retroperitoneal bleed. Hemoglobin and hematocrit +remained stable throughout hospital stay. +. +# H/o breast CA and papillary bladder CA: Stable. Patient +advised to continue outpatient follow-up per primary oncologist. +. +FEN: Patient was maintained on cardiac prudent diet. +Electrolytes were repleted as necessary. +. +PROPHYLAXIS: SCD's were used for DVT prophylaxis. +. +CODE: FULL + +Medications on Admission: +Atenolol 25mg daily, last dose [**2190-10-3**] +Lunesta 2mg qhs +Alprazolam 0.25mg daily in the am, [**1-29**] tablet at noon, 1 tablet +at night PRN +Simvastatin 30mg daily +MVI daily +Vitamin D daily +Vitamin B12 500mcg daily +Calcium, magnesium daily +Fish oil 1000mg daily +Asa 81mg daily +. + +Discharge Medications: +1. Simvastatin 10 mg Tablet Sig: Three (3) Tablet PO DAILY +(Daily). +2. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Atenolol 25 mg Tablet Sig: One (1) Tablet PO once a day. +4. Cholecalciferol (Vitamin D3) 400 unit Tablet Sig: One (1) +Tablet PO DAILY (Daily). +5. Cyanocobalamin 100 mcg Tablet Sig: 0.5 Tablet PO DAILY +(Daily). +6. Omega-3 Fatty Acids Capsule Sig: One (1) Capsule PO DAILY +(Daily). +7. Aspirin 81 mg Tablet, Chewable Sig: One (1) Tablet, Chewable +PO DAILY (Daily). +8. Alprazolam 0.25 mg Tablet Sig: One (1) Tablet PO once a day. + +9. Ibuprofen 400 mg Tablet Sig: 1-2 Tablets PO three times a day +as needed for pain: please take with food. +10. Lunesta 2 mg Tablet Sig: One (1) Tablet PO at bedtime. + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +Supraventricular tachycardia, AVRT +Pericardial effusion + +Secondary Diagnoses: +1. CARDIAC RISK FACTORS: - Diabetes, + Dyslipidemia, - +Hypertension +2. CARDIAC HISTORY: +-CABG: N/A +-PERCUTANEOUS CORONARY INTERVENTIONS: N/A +-PACING/ICD: N/A +3. OTHER PAST MEDICAL HISTORY: +- Total abdominal hysterectomy and salpingoophrectomy [**2164**] r/t +endometriosis +- Left breast cancer diagnosed [**2180**] s/p Left lumpectomy and +radiation therapy +- Papillary bladder cancer diagnosed [**2180**] s/p multiple +resections +and chemotherapy, finished [**2190-4-28**] +- [**2190-3-5**] s/p right ureteral stent, ? transitional cell cancer +of +the right ureteral orifice +- Anxiety + + +Discharge Condition: +stable and improved + + +Discharge Instructions: +You were admitted to the hospital for a procedure to fix an +abnormal rhythm in your heart. The procedure was unable to be +finished because of concern for build up of fluid around your +heart. Ultrasounds of your heart showed that the fluid around +your heart was not getting worse. You were discharged on +[**2190-10-10**], and will have close follow up with Dr. [**Last Name (STitle) **]. +Please follow up in 6 weeks for liver ultrasound to follow up +liver cyst. + +No changes were made to your medications. + +Please see below for your follow up appointment with Dr. +[**Last Name (STitle) 1911**]. + +Please call your physician [**Last Name (NamePattern4) **] 911 if you develop chest pain, +shortness of breath, worsening palpitations, +dizziness/lightheadedness, fevers, chills, or any other +concerning medical symptoms. + + +Followup Instructions: +Please follow up with Dr. [**Last Name (STitle) 1911**] tomorrow, [**2190-10-11**]. +Please call [**Telephone/Fax (1) 11767**]. You have another appointment with Dr. +[**Last Name (STitle) 11649**] on [**2190-10-26**], see below. + +[**Last Name (un) 1918**] [**Doctor Last Name **] Phone:[**Telephone/Fax (1) 11767**] Date/Time:[**2190-10-26**] 10:40 + + + +",12,2190-10-08 16:50:00,2190-10-10 13:00:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOME,SUPRAVENTRICULAR TACHYCARDIA\SUPRAVENTRICULAR TACHYCARDIA ABLATION," +66 y/o lady with history of svt now with pericardial effusion +s/p attempted ep ablation. +. +# pericardial effusion/pump: patient was found to have a 1.4 cm +anterior pericardial effusion after she became hypotensive +during svt ablation procedure on [**2190-10-8**]. tte also showed mild +ra collapse without any rv collapse. emergently, patient +received a right heart cath that was consistent with a +non-hemodynamically signicant effusion w/o tamponade physiology, +so pericardiocentesis was not felt to be indicated. (cardiac +output was preserved and there was no equalization of filling +pressures.) swan-ganz was initially left in place to monitor for +development of tamponade physiology. arterial line was also +placed for blood pressure monitoring. patient was initially +hypotensive, but her blood pressure was responsive to iv fluid +hydration and dopamine. her blood pressure remained stable over +the next 24 hours, and a repeat tte on [**10-9**] did not show +worsening of the pericardial effusion. chest pain secondary to +the pericardial effusion was well-controlled with toradol and +patient was discharged on ibuprofen prn for pain. +. +# rhythm: prior to admission, svt was thought be a narrow +complex tachycardia at 150 beats/minute with an rp interval of +100-120 msec. however, immediately post adenosine, there was +evidence of sinus rhythm with a fully pre-excited qrs complex +consistent with a left lateral bypass tract. in ep lab, +monitors showed left lateral ventricular pre-excitation, +retrograde va block via bt at 350 msec, anterograde bt block +at 300 msec, and atypical induced orthodromic avrt, cl 400 msec +via left lateral bt. during the procedure, it was difficult +crossing the av, and ablations were performed primarily at the +entrent atrial acitivation site during vpacing. also slow +pathway ablation was performed to prevent initiation of the +avrt. the ablation procedure was incomplete given hypotension +as above. rhythm was monitored on telemetry and showed +predominantly sinus rhythm. +. +# coronaries: patient has no known cad. chest pain while +inpatient was pleuritic in nature and attributed to +hemopericardium. asa was continued. +. +# extensive groin manipulation: due to extensive groin +manipulation during cardiac procedures on [**2190-10-8**], patient was +monitored closely for evidence of retroperitoneal bleed. in the +cath lab, heparin was reversed with protamine, post cath checks +were unremarkable, and a ct scan of abdomen and pelvis was +negative for a retroperitoneal bleed. hemoglobin and hematocrit +remained stable throughout hospital stay. +. +# h/o breast ca and papillary bladder ca: stable. patient +advised to continue outpatient follow-up per primary oncologist. +. +fen: patient was maintained on cardiac prudent diet. +electrolytes were repleted as necessary. +. +prophylaxis: scds were used for dvt prophylaxis. +. +code: full + + ","PRIMARY: [Other specified cardiac dysrhythmias] +SECONDARY: [Cardiac complications, not elsewhere classified; Unspecified disease of pericardium; Other iatrogenic hypotension; Other specified surgical operations and procedures causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation; Other and unspecified hyperlipidemia; Anxiety state, unspecified; Other specified disorders of liver; Personal history of malignant neoplasm of bladder; Personal history of malignant neoplasm of breast; Other postprocedural status]" +85258,179741.0,29926,2131-04-11,29853,122457.0,2131-01-19,Discharge summary,"Admission Date: [**2130-12-4**] Discharge Date: [**2131-1-19**] + +Date of Birth: [**2090-5-18**] Sex: F + +Service: MEDICINE + +Allergies: +Roxicet + +Attending:[**First Name3 (LF) 4057**] +Chief Complaint: +Nausea, Vomiting + +Major Surgical or Invasive Procedure: +Tracheostomy +thoracentesis +Left VATS +Mechanical Ventilation + + +History of Present Illness: +40 yo F with unresectable esophageal cancer who was recently +discharged from the hospital secondary to right neck pain. She +was then discharged on [**12-1**]. Notes indicate the patient +re-presented on [**12-4**] with the chief complaint of ""strange +sounding airway"" and dyspnea. She was found to have a soft +tissue infection lateral to the esophagus that likely represents +microperforation, for which she was started on abx, and she +required surgical tracheostomy for upper airway obstruction +caused by her esophageal cancer. +. +Additionally, her MICU course was remarkable for persistent +tachycardia and mild hypotension. Her heart rate remains 120s at +rest with brief episodes of rates as high as 150 when she is out +of bed, sinus tachycardia at all times. Her blood pressure has +ranged from 70s-90s systolic, which does not appear to be new, +as OMR notes document systolic blood pressures in the high +80s-low 90s at multiple visits. Evaluation as to the cause of +tachycardia has included TSH (low normal), with fT4 pending; +echo (nml LV and RV function, no echocardiographic signs of +hemodynamically significant PE); ABG 7.46/41/114 was with pt +breathing room air for 10 minutes, indicating that there is no +apparent A-a gradient; a random cortisol level was low, but +responded appropriately to cosyntropin. Since she appears well, +with good skin turgor and adequate urine output, despite the +tachycardia and hypotension, she was transferred out of the ICU. + + + +Past Medical History: +#. Invasive Esophageal Squamous Squamous Cell Carcinoma: +- [**2129-11-1**]: Pt arrived in America from [**Country 3587**] +- [**2129-11-2**]: Pt evaluated for Odynophagia, tx with Prilosec +- 11/26-30/07: Admitted fo Esophageal Web Dilations that +relieved symptoms +- [**1-4**]: Symptoms of odynophagia returned +- [**2130-2-12**]: Referred to ENT for recurrent cervial web at C4-5 +- [**2130-4-14**]: Esophageal Dilation under general anesthesia +- [**5-4**]: ENT consult for bilateral submandibular pain +- 5/29-30/08: Two subsequent attempts at dilation unsucessful +- [**6-4**]: PEG placed for FTT +- [**2130-6-7**]: Bx confirms Invasive Squamous Cell CA +- [**2130-6-20**]: +diagnosed [**2130-5-28**] in +setting of esophageal stricture +- high cervical esophageal lesion not resectable +- completed therapy with Cetuximab and radiation therapy +# Anemia +# Upper esophageal and pharyngeal stricture; s/p PEG +# Shoulder Pain +# Lung lesion - NOS +# Chronic pain from radiation. +# Nausea and vomiting. +# PEG tube site candidiasis + + +Social History: +The patient lives in [**Location 686**], MA with her cousin [**Name (NI) **] [**Name (NI) **], +who is her HCP. The patient is initially from [**Country 11660**] +islands, she is not currently working. +Tobacco: None +ETOH: None +Illicits: None + + +Family History: +There is no history in her family of heart disease, gastric +cancer, esophageal cancer or colon cancer or inflammatory bowel +disease. + + +Physical Exam: +ADMISSION PHYSICAL EXAM +VS: T = 99.4 P = 120 BP = 108/60 RR 16, O2Sat:100% +GENERAL: Young female who appears older than her stated age. +She is appears tired and worn. +Mentation: Alert but restricted affect. Does not smile. +Eyes:NC/AT, PERRL, EOMI without nystagmus, no scleral icterus +noted +Ears/Nose/Mouth/Throat: MMM, no lesions noted in OP +Neck: supple, no JVD or carotid bruits appreciated +Respiratory: Bibasilar crackles +Cardiovascular: tachy, nl. S1S2, no M/R/G noted +Gastrointestinal: soft, NT/ND, normoactive bowel sounds, no +masses or organomegaly noted. +PEG site C/D/I no odor. Appears better than during previous +admission. +Genitourinary: +Skin: no rashes or lesions noted. No pressure ulcer +Extremities: No C/C/E bilaterally, 2+ radial, DP and PT pulses +b/l. +Lymphatics/Heme/Immun: No cervical lymphadenopathy noted. +Neurologic: +-mental status: Alert, oriented x 3. Able to relate history +without difficulty. +-cranial nerves: II-XII intact +-motor: normal bulk, strength and tone throughout. No abnormal +movements noted. +-DTRs: 2+ biceps, triceps, +No foley catheter/tracheostomy/PEG/ventilator support/chest +tube/colostomy +Psychiatric: Very limited affect with rare brightening. +. +PHYSICAL EXAM UPON ARRIVAL TO THE FLOOR: [**12-11**] +Vitals: T97.9 BP96/50 HR126 RR19 O2Sat100% on 35% trach collar +GEN: Thin, tired-appearing [**Location 7972**] woman +HEENT: EOMI, PERRL, sclera anicteric, no epistaxis or +rhinorrhea, MMM, OP Clear +NECK: No JVD, carotid pulses brisk, no bruits, no cervical +lymphadenopathy, trachea with sutured trach cannula +COR: tachy, no M/G/R, normal S1 S2, radial pulses +2 +PULM: bronchial [**Location 1440**] sounds throughout +ABD: Soft, NT, ND, +BS, no HSM, no masses. PEG in place in LUQ +EXT: No C/C/E, no palpable cords +NEURO: alert, oriented to person, place, and time. CN II ?????? XII +grossly intact. Moves all 4 extremities. Strength 5/5 in upper +and lower extremities. Patellar DTR +1. Plantar reflex +downgoing. No gait disturbance. No cerebellar dysfunction. +SKIN: Normal turgor. No jaundice, cyanosis, or gross dermatitis. +No ecchymoses. + +Pertinent Results: +[**2130-12-4**] Neck CT: +1. No mass lesions are detected within the airway to explain +stridorous +breathing. +2. Fluid again noted within the esophagus in the region of the +thyroid gland. Also noted on prior study, possibly relating to +region of stricture. +3. Slight increase in cavitary lesion within the left lung apex. + + +NOTE ADDED AT ATTENDING REVIEW: There is a collection of air in +the right +neck, apparently just lateral to the esophagus, but possibly +within a dilated esophagus, best seen on images 34-37 of series +2. In this location it raises the possibility of an esophageal +perforation. Since it is difficult to determine the location of +the lateral margin of the esophagus, it is difficult to +distinguish an extraluminal collection from dilatation of the +organ. An MR examination may be helpful. + +There is induration of the adjacent tissues, which could be a +consequence of local infection, but also could arise as a result +of prior radiation. +. +[**2130-12-4**] CT CHEST +1. Small pharyngeal or paralaryngeal abscess, phlegmon or +malignancy has +grown over two weeks. If the lesion is inflammatory it suggests +ulceration in the hypopharynx/upper esohagus. Please see report +of today's neck CT. +2. Slow growth of small left upper lobe lung cavity and a tiny +right lower +lobe lesion as well as a new left lower lobe lesion are +concerning for +multifocal metastases, or slow spread of an indolent infection. +Small growing +left pleural mass is more characteristic of metastasis. +. +[**2130-12-6**] MRI SOFT TISSUE NECK, W/O & W/CONTRAST +IMPRESSION: 12 x 8 mm collection of air with small amount of +fluid just +anterior to the right aspect of the esophagus at the level of +the thyroid +gland which likely represents esophageal perforation and/or +abscess. +Additional considerations include esophageal diverticulum, +although less +likely. +. +TTE (Complete) Done [**2130-12-11**] at 2:38:57 PM +Conclusions +The left atrium is normal in size. No atrial septal defect is +seen by 2D or color Doppler. The estimated right atrial pressure +is 0-5 mmHg. Left ventricular wall thickness, cavity size and +regional/global systolic function are normal (LVEF >55%). There +is no ventricular septal defect. Right ventricular chamber size +and free wall motion are normal. The aortic valve leaflets (3) +appear structurally normal with good leaflet excursion and no +aortic regurgitation. The mitral valve appears structurally +normal with trivial mitral regurgitation. The estimated +pulmonary artery systolic pressure is normal. There is no +pericardial effusion. +Compared with the prior study (images reviewed) of [**2130-2-28**], no +change. +. +[**2130-12-12**] CTA CHEST +1. No pulmonary embolism. +2. New left posterior pleural lesion. Although this would be an +atypical +location for an esophageal carcinoma metastasis, the possibility +of malignancy cannot be totally excluded and PET CT may provide +additional diagnostic information. +3. Increase in right lower lobe and left upper lobe opacities +and new left +lower lobe opacity most likely represent infectios process; from +the same or different [**Doctor Last Name 360**] +4. Resolution of fluid collection in the posterior +parapharyngeal space +compared to the CT of [**2130-12-4**]., now fluid filled +. +[**2130-12-17**] CXR +Tracheostomy tube is again visualized. There is new left small +pleural effusion with volume loss in the left lower lobe. An +early infiltrate in this region cannot be totally excluded. +Otherwise, the lungs are clear. +. +LABWORK: +[**2130-12-4**] 08:42PM GLUCOSE-112* UREA N-13 CREAT-0.5 SODIUM-133 +POTASSIUM-5.0 CHLORIDE-92* TOTAL CO2-29 ANION GAP-17 +[**2130-12-4**] 08:42PM estGFR-Using this +[**2130-12-4**] 08:42PM HCG-<5 +[**2130-12-4**] 08:42PM CALCIUM-9.2 PHOSPHATE-2.4* MAGNESIUM-2.0 +[**2130-12-4**] 08:42PM WBC-9.6 RBC-3.35* HGB-9.8* HCT-28.8* MCV-86 +MCH-29.2 MCHC-34.0 RDW-14.7 +[**2130-12-4**] 08:42PM NEUTS-81.3* LYMPHS-12.0* MONOS-5.8 EOS-0.8 +BASOS-0.1 +[**2130-12-4**] 08:42PM PLT COUNT-672* +[**2130-12-4**] 08:42PM PT-14.3* PTT-25.5 INR(PT)-1.2* +. +Hematology + COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2131-1-19**] 12:00AM + 4.8 3.02* 9.5* 26.6* 88 31.4 35.8* 13.4 377 +Source: Line-PICC +[**2131-1-18**] 12:00AM + 4.7 3.14* 9.5* 26.8* 85 30.4 35.6* 13.9 356 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM + 5.4 3.38* 10.2* 29.4* 87 30.1 34.6 13.8 368 +Source: Line-PICC +[**2131-1-16**] 12:00AM + 4.0 3.51* 10.6* 30.7* 88 30.2 34.6 14.0 359 +Source: Line-PICC +[**2131-1-15**] 02:04AM + 5.0 3.17* 9.5* 26.8* 85 30.0 35.5* 14.8 352 +Source: Line-arterial +[**2131-1-14**] 04:41AM + 7.8 3.28* 10.2* 27.7* 84 31.1 36.9* 14.6 358 +Source: Line-arterial +[**2131-1-13**] 10:21PM + 10.6 3.44*# 10.9*# 29.0*#1 84 31.6 37.5* 14.0 425 +Source: Line-arterial +[**2131-1-13**] 02:24AM + 7.3 2.70* 8.2* 23.1* 85 30.4 35.6* 14.3 415 +Source: Line-aline +[**2131-1-12**] 06:20PM + 7.4# 2.71* 8.1* 23.2* 86 30.1 35.1* 14.3 356 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 4.2 2.93* 8.8* 25.7* 88 29.9 34.1 13.9 389 +[**2131-1-10**] 05:45AM + 3.7* 3.08* 9.1* 26.7* 87 29.6 34.2 13.9 420 +[**2131-1-9**] 06:15AM + 3.7* 3.09* 9.2* 26.3* 85 29.9 35.2* 14.0 430 +[**2131-1-8**] 05:35AM + 3.9* 3.26* 9.8* 28.2* 87 30.1 34.8 13.9 431 +[**2131-1-6**] 05:40AM + 3.3* 3.24* 9.8* 27.5* 85 30.4 35.8* 14.5 409 +[**2131-1-5**] 07:20AM + 3.2* 3.24* 10.1* 28.1* 87 31.1 35.9* 14.4 386 +[**2131-1-4**] 06:30AM + 3.4* 3.60* 11.0* 31.1* 86 30.6 35.5* 14.5 431 +[**2131-1-3**] 01:45PM + 4.3# 3.70* 11.3* 32.2* 87 30.6 35.1* 14.5 441* +[**2131-1-2**] 07:45AM + 2.5* 3.06* 9.1* 27.2* 89 29.7 33.5 14.5 363 +[**2131-1-1**] 06:50AM + 2.4* 3.11* 9.3* 27.0* 87 29.8 34.4 14.6 386 +[**2130-12-31**] 05:50AM + 2.2* 3.11* 9.3* 27.2* 88 29.9 34.2 14.3 372 +[**2130-12-30**] 06:00AM + 2.3* 3.26* 9.9* 29.0* 89 30.4 34.2 13.9 376 +[**2130-12-29**] 06:45AM + 2.1* 3.07* 9.2* 27.1* 88 29.8 33.8 13.8 344 +[**2130-12-28**] 05:55AM + 2.1* 3.17* 9.7* 28.2* 89 30.7 34.6 14.6 381 +[**2130-12-27**] 10:00AM + 2.0* 3.19* 9.6* 28.2* 88 29.9 33.9 14.5 420 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM + 1.7* 3.10* 9.8* 27.5* 89 31.5 35.6* 13.9 320 +[**2130-12-25**] 06:15AM + 2.3* 2.92* 8.9* 25.3* 87 30.4 35.1* 13.9 340 +[**2130-12-24**] 05:50AM + 2.7* 2.97* 9.1* 25.4* 86 30.6 35.8* 14.7 331 +[**2130-12-22**] 05:35AM + 2.7* 2.98* 8.8* 26.2* 88 29.4 33.5 14.9 337 +[**2130-12-21**] 06:00AM + 2.4* 3.03* 9.2* 26.6* 88 30.4 34.6 14.4 303 +[**2130-12-20**] 05:50AM + 2.3* 3.00* 8.9* 25.8* 86 29.7 34.5 15.3 308 +[**2130-12-19**] 07:00AM + 3.0* 3.30* 10.1* 29.2* 89 30.5 34.5 15.3 302 +[**2130-12-16**] 09:05AM + 3.4* 3.46*# 10.3*# 30.0* 87 29.9 34.5 15.9* 327 +[**2130-12-15**] 03:35PM 29.9* +[**2130-12-14**] 07:40AM + 5.4 2.75* 8.2* 24.6* 90 29.8 33.3 15.7* 358 +[**2130-12-13**] 08:00AM + 9.0 2.99* 9.0* 26.0* 87 30.1 34.7 15.6* 378 +[**2130-12-12**] 07:45AM 6.0 2.92* 8.7* 25.7* 88 29.9 34.0 15.3 387 +[**2130-12-11**] 04:22AM 6.9 2.97* 8.9* 26.1* 88 30.0 34.1 15.3 415 +[**2130-12-10**] 04:26AM + 8.4 3.08* 9.1* 26.7* 87 29.4 33.9 15.1 457* +[**2130-12-9**] 04:54AM + 9.1 2.88* 8.8* 25.0* 87 30.6 35.3* 15.1 466* +[**2130-12-8**] 06:10AM + 7.0 3.10* 9.0* 26.8* 87 29.1 33.6 14.6 514* +[**2130-12-7**] 03:47AM + 12.8*# 3.43* 10.4* 30.3* 88 30.2 34.2 15.2 645* +[**2130-12-6**] 03:18AM + 7.9 3.23* 9.7* 27.8* 86 30.2 35.0 15.0 633* +[**2130-12-5**] 10:00AM + 7.4 3.19* 9.1* 27.9* 87 28.4 32.5 15.2 553* +[**2130-12-4**] 08:42PM + 9.6 3.35* 9.8* 28.8* 86 29.2 34.0 14.7 672* + +VERIFIED LABEL + +D +IFFERENTIAL Neuts Bands Lymphs Monos Eos Baso Atyps Metas Myelos +[**2131-1-12**] 06:20PM 89.5* 6.6* 2.6 1.2 0 +Source: Line-arterial ulnar +[**2131-1-6**] 05:40AM 57 2 20 13* 4 0 2* 1* 1* +[**2131-1-5**] 07:20AM 60.3 21.8 10.3 7.5* 0.1 +[**2131-1-4**] 06:30AM 62.9 25.3 7.3 4.4* 0.2 +[**2131-1-3**] 01:45PM 70.2* 16.9* 7.7 5.1* 0.1 +[**2131-1-1**] 06:50AM 53.0 27.4 10.5 8.7* 0.4 +[**2130-12-31**] 05:50AM 56 0 36 4 1 0 3* 0 0 +[**2130-12-30**] 06:00AM 39.8* 42.9* 11.6* 5.4* 0.3 +[**2130-12-29**] 06:45AM 45.6* 32.4 13.0* 8.7* 0.3 +[**2130-12-28**] 05:55AM 27* 3 56* 9 3 0 2* 0 0 +[**2130-12-27**] 10:00AM 31* 0 40 18* 10* 1 0 0 0 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 52.8 28.4 9.4 8.8* 0.6 +[**2130-12-25**] 06:15AM 50 0 28 14* 5* 2 1* 0 0 +[**2130-12-21**] 06:00AM 51.6 34.1 8.6 5.4* 0.3 +[**2130-12-8**] 06:10AM 84.1* 9.3* 5.7 0.7 0.1 +[**2130-12-4**] 08:42PM 81.3* 12.0* 5.8 0.8 0.1 + RED CELL +M +O +R +P +H +O +L +O +G +Y Hypochr Anisocy Poiklo Macrocy Microcy Polychr Ovalocy Schisto +[**2131-1-6**] 05:40AM + NORMAL1 1+ 1+ NORMAL 1+ OCCASIONAL 1+ OCCASIONAL + +NORMAL +MANUALLY COUNTED + BASIC COAGULATION (PT, PTT, PLT, INR) PT PTT Plt Smr Plt +Ct INR(PT) +[**2131-1-19**] 12:00AM 377 +Source: Line-PICC +[**2131-1-18**] 12:00AM 356 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 368 +Source: Line-PICC +[**2131-1-16**] 12:00AM 359 +Source: Line-PICC +[**2131-1-15**] 02:04AM 352 +Source: Line-arterial +[**2131-1-14**] 04:41AM 358 +Source: Line-arterial +[**2131-1-13**] 10:21PM 425 +Source: Line-arterial +[**2131-1-13**] 02:24AM 415 +Source: Line-aline +[**2131-1-12**] 06:20PM 356 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 389 +[**2131-1-12**] 01:00AM 14.5* 28.3 1.3* +[**2131-1-10**] 05:45AM 420 +[**2131-1-9**] 06:15AM 430 +[**2131-1-8**] 05:35AM 431 +[**2131-1-6**] 05:40AM NORMAL 409 +[**2131-1-5**] 07:20AM 386 +[**2131-1-4**] 06:30AM 431 +[**2131-1-3**] 01:45PM 441* +[**2131-1-3**] 01:45PM 13.0 27.7 1.1 +[**2131-1-2**] 07:45AM 363 +[**2131-1-1**] 06:50AM 386 +[**2130-12-31**] 05:50AM NORMAL 372 +[**2130-12-30**] 06:00AM 376 +[**2130-12-29**] 06:45AM 344 +[**2130-12-28**] 05:55AM 381 +[**2130-12-27**] 10:00AM NORMAL 420 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 320 +[**2130-12-25**] 06:15AM NORMAL 340 +[**2130-12-24**] 05:50AM 331 +[**2130-12-22**] 05:35AM 337 +[**2130-12-21**] 06:00AM 303 +[**2130-12-20**] 05:50AM 308 +[**2130-12-19**] 07:00AM 302 +[**2130-12-16**] 09:05AM 327 +[**2130-12-14**] 07:40AM 358 +[**2130-12-13**] 08:00AM 378 +[**2130-12-12**] 07:45AM 387 +[**2130-12-11**] 04:22AM 415 +[**2130-12-10**] 04:26AM 457* +[**2130-12-9**] 04:54AM 466* +[**2130-12-8**] 06:10AM 514* +[**2130-12-8**] 04:25AM 17.0* 29.6 1.5* +[**2130-12-7**] 03:47AM 645* +[**2130-12-6**] 03:18AM 633* +[**2130-12-5**] 10:00AM 553* +[**2130-12-4**] 08:42PM 672* +[**2130-12-4**] 08:42PM 14.3*1 25.5 1.2* + +HEMOLYZED, MODERATELY +INTERPRET RESULTS WITH CAUTION +Chemistry + RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2131-1-19**] 12:00AM 99 15 0.4 134 4.6 96 29 14 +Source: Line-PICC +[**2131-1-18**] 12:00AM 96 17 0.4 140 4.6 102 29 14 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 96 12 0.4 133 4.4 97 27 13 +Source: Line-PICC +[**2131-1-16**] 12:00AM 129* 7 0.4 133 4.5 95* 28 15 +Source: Line-PICC +[**2131-1-15**] 02:04AM 129* 7 0.4 138 3.6 105 26 11 +Source: Line-arterial +[**2131-1-14**] 04:41AM 160* 5* 0.5 137 4.2 104 25 12 +Source: Line-arterial +[**2131-1-13**] 10:21PM 192* 5* 0.4 135 3.6 100 27 12 +Source: Line-arterial +[**2131-1-13**] 02:24AM 87 4* 0.4 133 3.9 102 27 8 +Source: Line-aline +[**2131-1-12**] 06:20PM 99 5* 0.4 134 3.6 103 27 8 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 94 8 0.5 137 4.1 102 29 10 +[**2131-1-2**] 07:45AM 104 4* 0.5 139 3.8 101 32 10 +[**2131-1-1**] 06:50AM 101 4* 0.6 136 4.2 99 31 10 +[**2130-12-31**] 05:50AM 77 5* 0.5 136 4.31 100 30 10 +[**2130-12-30**] 06:00AM 82 4* 0.6 138 4.1 101 32 9 +[**2130-12-29**] 06:45AM 118* 4* 0.6 136 4.1 99 31 10 +[**2130-12-28**] 05:55AM 83 5* 0.5 137 4.0 100 31 10 +[**2130-12-27**] 10:00AM 49*2 5* 0.5 138 4.1 101 31 10 +SPECIMEN ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 122* 5* 0.5 134 3.8 100 28 10 +[**2130-12-25**] 06:15AM 78 6 0.5 137 3.9 102 30 9 +[**2130-12-24**] 05:50AM 79 6 0.4 137 4.0 101 30 10 +[**2130-12-22**] 05:35AM 83 6 0.5 138 4.3 102 32 8 +[**2130-12-21**] 06:00AM 78 6 0.5 139 4.0 102 30 11 +[**2130-12-20**] 05:50AM 77 7 0.5 136 3.7 101 30 9 +[**2130-12-19**] 07:00AM 105 7 0.7 139 4.2 101 30 12 +[**2130-12-16**] 09:05AM 106* 8 0.6 137 4.2 100 30 11 +[**2130-12-14**] 07:40AM 96 6 0.5 138 4.3 104 29 9 +[**2130-12-13**] 08:00AM 124* 7 0.5 134 4.2 97 31 10 +[**2130-12-12**] 07:45AM 110* 7 0.5 136 4.0 102 30 8 +[**2130-12-11**] 04:22AM 107* 6 0.5 137 4.0 102 29 10 +[**2130-12-10**] 04:26AM 116* 7 0.6 131* 3.5 98 27 10 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM +[**2130-12-9**] 08:38AM 3.3 +[**2130-12-9**] 04:54AM 97 8 0.6 132* 5.9*3 98 28 12 +GROSS HEMOLYSIS +[**2130-12-8**] 04:25AM 97 13 0.7 135 3.9 99 30 10 +[**2130-12-7**] 03:47AM 142* 15 0.6 133 4.5 97 29 12 +[**2130-12-6**] 03:18AM 138* 10 0.5 136 4.2 98 29 13 +[**2130-12-5**] 10:00AM 115* 10 0.5 132* 4.3 95* 29 12 +[**2130-12-4**] 08:42PM 112* 13 0.5 133 5.04 92* 29 17 +MODERATELY HEMOLYZED SPECIMEN + +HEMOLYSIS FALSELY ELEVATES K +HEMOLYZED, SLIGHTLY +VERIFIED BY REPLICATE ANALYSIS +NOTIFIED T. [**Doctor Last Name **] AT 131PM ON [**2130-12-27**] +HEMOLYSIS FALSELY INCREASES THIS RESULT +HEMOLYSIS FALSELY ELEVATES K. + ESTIMATED GFR (MDRD CALCULATION) estGFR +[**2131-1-12**] 01:00AM Using this1 + +Using this patient's age, gender, and serum creatinine value of +0.5, +Estimated GFR = >75 if non African-American (mL/min/1.73 m2) +Estimated GFR = >75 if African-American (mL/min/1.73 m2) +For comparison, mean GFR for age group 40-49 is 99 (mL/min/1.73 +m2) +GFR<60 = Chronic Kidney Disease, GFR<15 = Kidney Failure + ENZYMES & +B +ILIRUBIN ALT AST LD(LDH) CK(CPK) AlkPhos Amylase TotBili DirBili +[**2131-1-14**] 04:41AM 172* +Source: Line-arterial +[**2131-1-13**] 10:21PM 217* +Source: Line-arterial +[**2131-1-2**] 07:45AM 129 +[**2130-12-5**] 09:10AM 52 +[**2130-12-5**] 01:35AM 48 + CPK ISOENZYMES CK-MB cTropnT +[**2131-1-14**] 04:41AM 2 <0.011 +Source: Line-arterial +[**2131-1-13**] 10:21PM 2 <0.011 +Source: Line-arterial +[**2130-12-5**] 09:10AM 1 <0.011 +[**2130-12-5**] 01:35AM 1 LESS THAN 2 + +<0.01 +CTROPNT > 0.10 NG/ML SUGGESTS ACUTE MI +LESS THAN 0.01 +CTROPNT > 0.10 NG/ML SUGGESTS ACUTE MI + CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2131-1-19**] 12:00AM 3.9 9.0 2.5* 2.1 +Source: Line-PICC +[**2131-1-18**] 12:00AM 9.4 2.5* 2.1 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 9.1 3.1 2.2 +Source: Line-PICC +[**2131-1-16**] 12:00AM 9.2 2.9 2.1 +Source: Line-PICC +[**2131-1-15**] 02:04AM 8.2* 1.9* 1.8 +Source: Line-arterial +[**2131-1-14**] 04:41AM 8.8 1.3* 1.8 +Source: Line-arterial +[**2131-1-13**] 10:21PM 8.6 1.6* 1.7 +Source: Line-arterial +[**2131-1-13**] 02:24AM 8.3* 2.8 2.1 +Source: Line-aline +[**2131-1-12**] 06:20PM 2.3* 7.8* 3.1 1.2* +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 8.7 2.9 2.0 +[**2131-1-2**] 07:45AM 6.0* 9.2 3.8 2.0 +[**2131-1-1**] 06:50AM 9.3 3.7 1.9 +[**2130-12-31**] 05:50AM 8.9 3.5 2.01 +[**2130-12-30**] 06:00AM 9.6 3.5 2.0 +[**2130-12-29**] 06:45AM 8.9 3.4 1.9 +[**2130-12-27**] 10:00AM 9.0 3.3 2.0 +SPECIMEN ARRIVED IN LAB AT 12:41PM +[**2130-12-25**] 06:15AM 9.0 3.2 1.9 +[**2130-12-24**] 05:50AM 1.9 +[**2130-12-21**] 06:00AM 1.9 +[**2130-12-20**] 05:50AM 9.0 3.4 1.9 +[**2130-12-19**] 07:00AM 9.5 3.4 2.0 +[**2130-12-16**] 09:05AM 1.9 +[**2130-12-14**] 07:40AM 8.6 3.3 1.8 +[**2130-12-13**] 08:00AM 8.9 3.1 1.9 +[**2130-12-12**] 07:45AM 8.5 2.3* 1.9 +[**2130-12-11**] 04:22AM 9.0 2.7 1.8 +[**2130-12-10**] 04:26AM 8.9 2.5* 1.8 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM +[**2130-12-9**] 08:38AM 1.8 +[**2130-12-9**] 04:54AM 9.0 3.5 1.81 +GROSS HEMOLYSIS +[**2130-12-8**] 04:25AM 9.1 3.2 1.8 +[**2130-12-7**] 03:47AM 9.8 3.1 2.0 +[**2130-12-6**] 03:18AM 10.0 3.8 1.9 +[**2130-12-5**] 10:00AM 8.5 2.9 1.8 +[**2130-12-4**] 08:42PM 9.2 2.4* 2.02 +MODERATELY HEMOLYZED SPECIMEN + +HEMOLYSIS FALSELY ELEVATES Mg +HEMOLYSIS FALSELY ELEVATES MG. +OTHER CHEMISTRY Osmolal +[**2131-1-13**] 10:21PM 277 +Source: Line-arterial + PITUITARY TSH +[**2130-12-31**] 05:50AM 1.5 +[**2130-12-11**] 04:22AM 0.12* +[**2130-12-10**] 04:26AM 0.29 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM + THYROID T4 T3 calcTBG TUptake T4Index Free T4 +[**2130-12-13**] 08:00AM 12.9* 1.02 0.98 12.6* +[**2130-12-12**] 07:45AM 13.1* 122 1.9* + OTHER ENDOCRINE Cortsol +[**2131-1-13**] 03:34PM 31.3*1 +PLEASE MEASURE THIRTY MINUTES AFTER COSYNTROPIN +[**2131-1-13**] 02:59PM 21.0*1 +[**2130-12-10**] 11:17PM 25.6*1 +[**2130-12-10**] 10:57PM 17.91 +[**2130-12-10**] 10:14PM 4.11 +[**2130-12-10**] 04:26AM 0.9*1 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM + +NORMAL DIURNAL PATTERN: 7-10AM 6.2-19.4 / 4-8PM 2.3-11.9 +GYNECOLOGIC HCG +[**2130-12-4**] 08:42PM <51 +MODERATELY HEMOLYZED SPECIMEN + +<5 +<5 IS NEGATIVE; 5 - 25 IS EQUIVOCAL; >25 IS POSITIVE +LAB USE ONLY RedHold +[**2131-1-6**] 05:40AM HOLD +Blood Gas + BLOOD GASES Type Temp Rates Tidal V PEEP FiO2 O2 +Flow pO2 pCO2 pH calTCO2 Base XS Intubat Comment +[**2131-1-13**] 02:36AM ART 201* 48* 7.40 31* 4 +[**2131-1-12**] 08:41PM ART 35 156* 44 7.42 30 4 NOT +INTUBA1 TRACH MASK +[**2130-12-11**] 08:46PM ART 114* 41 7.46* 30 5 +[**2130-12-8**] 12:33PM ART 159* 38 7.48* 29 5 + +NOT INTUBATED +WHOLE BLOOD, MISCELLANEOUS CHEMISTRY Lactate +[**2131-1-12**] 08:41PM 0.8 +. + +Pathology Examination +Name Birthdate Age Sex Pathology # [**Hospital1 18**] [**Known lastname 71385**],[**Known firstname **] [**Last Name (NamePattern1) 71386**] [**2090-5-18**] 40 Female + [**-7/4872**] [**Numeric Identifier 71387**] +Report to: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) 1533**] +Gross Description by: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **] GOODELL/dif + +SPECIMEN SUBMITTED: Tracheal Tissue. + +Procedure date Tissue received Report Date Diagnosed +by +[**2130-12-8**] [**2130-12-8**] [**2130-12-13**] DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **]/ttl +Previous biopsies: [**-7/2145**] G I BIOPSY (1 JAR). + [**-6/4630**] GASTRIC BX. + [**Numeric Identifier 71388**] RIGHT AND LEFT SEGMENT OF FALLOPIAN TUBES (2). + +DIAGNOSIS: + +Trachea, biopsy: +1. Unremarkable cartilage. +2. Paratracheal soft tissue with acute and chronic +inflammation; no malignancy identified. +. +Pathology Examination +Name Birthdate Age Sex Pathology # [**Hospital1 18**] [**Known lastname 71385**],[**Known firstname **] [**Last Name (NamePattern1) 71386**] [**2090-5-18**] 40 Female + [**Numeric Identifier 71389**] [**Numeric Identifier 71387**] +Report to: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) 1533**] +Gross Description by: DR. [**Last Name (STitle) **]. [**Doctor Last Name **]/dif + +SPECIMEN SUBMITTED: posterior pleural plaque, inferior pleural +plaque, upper lobe wedge. + +Procedure date Tissue received Report Date Diagnosed +by +[**2131-1-12**] [**2131-1-12**] [**2131-1-16**] DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **]/dwc?????? +Previous biopsies: [**-7/4872**] Tracheal Tissue. + [**-7/2145**] G I BIOPSY (1 JAR). + [**-6/4630**] GASTRIC BX. + [**Numeric Identifier 71388**] RIGHT AND LEFT SEGMENT OF FALLOPIAN TUBES (2). + +DIAGNOSIS: +Pleura, left posterior plaque, biopsy (A-B): + + Metastatic squamous cell carcinoma. + +Pleura, left inferior plaque, biopsy (C-D): + + Metastatic squamous cell carcinoma. + +Lung, left upper lobe, wedge resection (E-J): + + Metastatic squamous cell carcinoma (see note). + + +Note: +(E-J): Apart from the largest tumor nodule (2 cm in greatest +dimension), multiple small foci of metastatic squamous cell +carcinoma are present along the pleural surface. The surgical +margin of resection appears to be free of tumor. + +Clinical: Esophageal mass, neck pain. +Gross: + +The specimen is received fresh labeled with the patient's name, +""[**Known lastname 19688**], [**Known firstname **] [**Last Name (NamePattern1) **]"", the medical record number and +""pleural plaque."" It consists of a fragment of white - tan firm +tissue measuring 2.5 x 1.5 x 0.6 cm, serially sectioned and +partially frozen. Intraoperative exam was performed. A frozen +section was performed on tissue. The frozen section diagnosis by +Dr. [**Last Name (STitle) **] is ""posterior pleural plaque: metastatic carcinoma."" + + +The remainder of the specimen is entirely submitted in A, frozen +section in B. + +Part 2 is additionally labeled ""inferior pleural plaque."" It +consists of a fragment of firm pink-tan tissue measuring 1.0 x +0.9 x 0.2 cm. The specimen is serially sliced and submitted in +C-D. + +Part 3 is additionally labeled ""left upper lobe wedge RUSH."" It +consists of a wedge resection of lung measuring 6.0 x 3.4 x 1.5 +cm with a stapled margin that measures 8.0 cm in length. The +pleural surface is smooth and shiny, and involved by a white +mass measuring 3.0 x 1.5 cm. This area is firm on palpation. +The specimen is serially sliced to reveal a 2.0 x 2.0 x 1.0 cm +white tan cystic well circumscribed, nodule, located 0.4 cm from +the nearest stapled margin. The mass involves the pleura. The +remainder of the lung parenchyma is unremarkable. The specimen +is represented as follows: E-F = pulmonary resection margin, G-I += tumor in relation to parietal pleura, J = unremarkable lung. +. + + +Brief Hospital Course: +The following summary is divided into sections due to the +patients prolonged hospital course: + +# Esophageal Cancer/Cough/SOB: The patient presented with cough +and SOB. Her symptoms progressed and ENT was consulted. The +patient was found to have superglottic swellling and she was +transferred to the ICU for concern of possible iminent airway +obstruction. A CT of the neck was concerning for perforation +and this finding was reassessed with MRI which raised the +possibility of abcess formation. Given these findings, throacic +surgery was consulted and it was felt that the patient would +benefit from tracheostomy placement for airway protection. A +trach was placed by thoracics on [**2130-12-8**] which was tolerated +well. Speech and swallow followed for assessment for passy muir +valve. + +[**Hospital Unit Name 71390**] COURSE [**12-6**] through [**12-11**] +. +[**12-6**] +- ENT - advised continued MICU care, trachea 3 mm at narrowest +point and supraglottic edema, R vocal cord paralysis +- Thoracics consult- likely not a tear; advised barium swallow +and broad spectrum coverage, ddx perforation vs TE fistula; +- Pt did not tolerate barium swallow +- Added Vanco/Levo/Flagyl/Fluconazole +- MR Neck - read PENDING (wet read by surgery - no ET fistula, +no extaluminal air) +- TFs - restart Ensure +- Evaluated for worsening stridor at 0400; Inspiratory stridor +noted on exam in all lung fields, but pt saturating well. Denies +worsening pain. Thoracics informed. +. +[**Date range (3) 71391**] +- MRI suggestive of micro-esophagael perf, +/- infection +- (Started on Vanco Levo Fluc yesterday [**12-6**]) +- ?Worsening stridor this Morning ([**12-7**]) around 4AM, self +resolved. +- Unless team observes persistent stridor, plan for continuing +Abx, no surgical (trach) intervention at this time. +- had rhoncorous [**Month/Year (2) 1440**] sounds, 3am, cleared on own. +[**12-8**] +- Had trachyostomy; tolerated procedure well. Weaned off vent +overnight and placed on trach mask. +- Per Thoracics, would attempt passy miur valve today. +. +[**12-9**] +- c/od but no bed +- ENT s/o +- CXR shows trach well palced +- tolerated trach proecedure well +- no stridor, no n/v +- restarted tube feeds +- thoracics - 2 wks antibx but will follow on the floor +- patient somewhat confused about cancer dx and prognosis - will +need to have [**Doctor Last Name **]/[**Doctor Last Name **] to explain to patient what to +expect for the future +- continues to be tachycardic +. +12/14-15/08 +-Assessment update: noting low suspicion for esophagael cancer +per Dr. [**Last Name (STitle) 174**]. Concern that chest lesion is met, but not +confirmed. Re: reversibility of trach--if this was esoph perf +[**1-29**] vomiting or [**1-29**] to radiation, likely temporary and may be +removed s/p f/u bronch. +-Refusing depression meds, psychiatry, social work +-Speech and Swallow tomorrow +-Gave 1 L for tachychardia +. +[**2130-12-10**] +Spoke to oncology team re: transfer. Concern that hemodynamics +are slightly worse than on admission. On admission SBPs in 90s, +HR in low 100s, now SBP in 80s, HR 110s. Documented baseline +blood pressures in all discharge summaries from [**2129**] have been +baseline SBPs in the 80s but without tachycardia. Will check +cortisol, TSH. +-Cortisol noted to be quite low. Have ordered supression test. +Will likely need to start treatment steroids s/p test. + +[**2130-12-11**] +-Continuing cough apprecaited. Secretions noted. +-In general, ""still""-appearing, as if in pain, but repeatedly +denies. +- hypotensive to 70's but not symptomatic. Tachy with normal +echo. Good UOP. +Summary of ICU Course: +Briefly, Mrs [**Known lastname 19688**] is a 40 yo F with unresectable esophageal +cancer who was recently discharged from the hospital secondary +to right neck pain. She was then discharged on [**12-1**]. Notes +indicate the patient re-presented on [**12-4**] with the chief +complaint of ""strange sounding airway"" and dyspnea. She was +found to have a soft tissue infection lateral to the esophagus +that likely represents microperforation, for which she was +started on abx, and she required surgical tracheostomy for upper +airway obstruction caused by her esophageal cancer. +. +Additionally, her MICU course was remarkable for persistent +tachycardia and mild hypotension. Her heart rate remains 120s at +rest with brief episodes of rates as high as 150 when she is out +of bed, sinus tachycardia at all times. Her blood pressure has +ranged from 70s-90s systolic, which does not appear to be new, +as OMR notes document systolic blood pressures in the high +80s-low 90s at multiple visits. Evaluation as to the cause of +tachycardia has included TSH (low normal), with fT4 pending; +echo (nml LV and RV function, no echocardiographic signs of +hemodynamically significant PE); ABG 7.46/41/114 was with pt +breathing room air for 10 minutes, indicating that there is no +apparent A-a gradient; a random cortisol level was low, but +responded appropriately to cosyntropin. Since she appears well, +with good skin turgor and adequate urine output, despite the +tachycardia and hypotension, she was transferred out of the ICU. + +The following section summarizes the patients OMED course +including VATS and SICU transfer: +. +40 y/o F with esophageal SCC s/p XRT, s/p tracheostomy for upper +airway compromise with parapharyngeal abscess, now s/p VATs for +LUL cavitary lesion and found to have metastatic esophageal CA. +. +#. Metastatic Esophageal CA: Patient s/p chemo and radiation. +The patient was noted to have a LUL cavitary lesion on CT scan +in early [**Month (only) **]. This was found to have grown by Janurary. +Concern that new lung lesion is secondary to metastatic disease. +A new left sided pleural effusion was seen on CT on [**1-1**]. The +patient underwent thoracentesis on [**1-2**] with 700cc of clear +yellow fluid drained without complication. Cytology and cultures +were sent and the patient was found to have an exudative +effusion. ID was consulted, fungal serologies and stool O&P were +sent. The patient was ruled out for TB on two separate +occasions. Sputum from [**1-5**] grew back Klebsiella Oxytoca, and on +[**1-6**] Acinetobacter both of which were thought to be a +contaminant. The patient was transfered to the [**Hospital Ward Name 516**] on +[**2131-1-12**] to undergo a VATS resection of the the cavitary lesion. +The patient underwent VATS on [**2130-1-11**] which unfortunately +revealed carcinomatous plaques on the pleural wall which were +confirmed frozen section. A chest tube was placed. The patient +briefly required pressers while in the SICU. These were weaned +and the patient was subsequently transfered back to the [**Hospital Ward Name 5074**] on [**1-15**]. Fungal serologies revealed strogyloides and the +patient was given two days of Ivermectin. The patient will +follow-up with Dr. [**Last Name (STitle) **] as an outpatient. +. +#. s/p Trach: The patient was trached on [**12-8**] secondary to +airway compromise. The patient has been breathing comfortably +with trach on 35% trach mask FM; ambulating without supplemental +oxygen; transient dyspnea improves with nebs, anxiolytics. The +patient did not tolerate a PMV on [**1-2**] following completion of a +28 day course of Unasyn and Clindamycin (previously Augmentin). +The patient did not tolerate her PMV mask on [**1-3**]. On [**1-4**] +respiratory therapy attempted to use inhaled fluticasone to +improve her symptoms. The patient was tolerating her PMV +incrementaly more each day. On [**1-7**] the patient was noted to +have increased TM requirements up to 50%. This was thought to be +potentially secondary to reaccumulation of her L pleural +effusion. The patients trach was changed to a 6.0 fenestrated +trach on [**1-16**]. The patient was decannulated by thoracics on [**1-17**] +which she tolerated. Supportive care should be continued upon +discharge. +. +# Healthcare Associated PNA: The patient developed fevers and +had continued cough following her VATS. The patient was placed +empirically on Cefepime on [**1-15**], this was later changed to +Levaquin upon discharge for a planned 10 day total duration of +antibiotics. Cultures were NGTD at the time of discharge. +. +# Parapharygneal Abscess. The patient was placed initially on +Augmentin. This was changed to Unasyn / Clindamycin for which +she subsequently completed 28 days of treatement. ENT evaluated +patient [**1-1**] no upper airway abnormality other than copious +secretions. A CT Neck and Chest on [**1-2**] revealed both +tetropharyngeal and retrotracheal swelling as well as soft +tissue density encompassing the esophagus. This was thought to +potentially represent post-radiation changes and phlegmon. No +evidence of a drainable fluid collection. +. +#. Neutropenia: Initially thought to be secondary to patients +being on augmentin. This was subsequently changed to +Clindamycin/Unasyn or compazine. ANC subsequenrly resolved to +1278 [**1-1**]. +. +#. Anemia: Currently at baseline, no signs of active bleeding. +Con't to monitor. There was question of benefit of higher +transfusion threshold to reduce tachycardia. +. +#. Tachycardia: The patient has been persistently in sinus +tachycardia 110-130 bpm. The patient was evaluate while in the +ICU that indicated a low probibility for PE, no signs of CHF, +and potentially subclinical hyperthyroidism although TSH WNL. +There was thought that part of the ST was secondary to anxiety. +Anemia also potentially played a role. +- Cont Tele +. +#. Hypotension: Asymptomatic and maintaining MAP >= 60. Responds +well to fluid bolus when systolics drift down to 70s. Continue +vol challenge prn. Was briefly on pressers while in the unit, +now weaned off. +. +#. Pain: The patients pain was well-controlled with gabapentin +and methadone. The patient was written for Morphine PRN. +. +# Depression: The patient remains on nortriptyline for depressed +mood and will not take additional treatment. Likely that some of +this is related to coping with general medical illness as well +as underlying depression and being away from her children. +- SW will cont to follow +- cont nortriptyline +. +#. Steroid-Induced DM: continue SSI; if requirements trend down +now that off steroids, can D/C insulin + +Medications on Admission: +Tylenol occasionaly +Lactulose 30 cc tid prn +Methadone 2.5 mg [**Hospital1 **] +. +Upon transfer out of the MICU: +. +Heparin 5000 UNIT SC TID +Insulin SC +Lactulose 30 mL PO Q8H:PRN Order date: [**12-12**] @ 0050 +Levofloxacin 750 mg IV Q24H day 1 = [**12-6**] +Methadone 2.5 mg PO BID +Acetaminophen (Liquid) 325-650 mg PO Q6H:PRN +MetRONIDAZOLE (FLagyl) 500 mg IV Q8H day 1 = [**12-6**] +Albuterol 0.083% Neb Soln 1 NEB IH Q6H:PRN +Nortriptyline 25 mg NG HS +Ondansetron 8 mg IV Q 8H +Pantoprazole 40 mg IV Q12H +Docusate Sodium (Liquid) 100 mg PO BID PRN +Prochlorperazine 25 mg PR Q12H +Fluconazole 200 mg NG Q24H day 1 = [**12-6**] +Gabapentin 300 mg PO QAM & 600 mg PO QPM +Vancomycin 1000 mg IV Q 12H day 1 = [**12-6**] + + +Discharge Medications: +1. Nortriptyline 10 mg/5 mL Solution [**Month/Year (2) **]: One (1) PO HS (at +bedtime). +2. Methadone 5 mg Tablet [**Month/Year (2) **]: 0.5 Tablet PO BID (2 times a day). + +3. Lactulose 10 gram/15 mL Syrup [**Month/Year (2) **]: Thirty (30) ML PO Q8H +(every 8 hours) as needed for constipation. +Disp:*300 ML(s)* Refills:*2* +4. Senna 8.8 mg/5 mL Syrup [**Month/Year (2) **]: Five (5) ML PO BID (2 times a +day). +Disp:*300 ML(s)* Refills:*2* +5. Acetaminophen 160 mg/5 mL Solution [**Month/Year (2) **]: [**12-29**] tsp PO Q6H (every +6 hours) as needed for fever or pain. +Disp:*1 Bottle* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup [**Month/Day (2) **]: Fifteen (15) ML PO Q6H +(every 6 hours) as needed for cough. +Disp:*200 ML(s)* Refills:*1* +7. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] DAILY (Daily). +Disp:*30 Tablet,Rapid Dissolve, DR(s)* Refills:*2* +8. Docusate Sodium 50 mg/5 mL Liquid [**Last Name (STitle) **]: Ten (10) mL PO BID (2 +times a day). +Disp:*600 mL* Refills:*2* +9. Bisacodyl 10 mg Suppository [**Last Name (STitle) **]: One (1) Suppository Rectal +[**Hospital1 **] (2 times a day) as needed for constipation. +10. Compazine 5 mg Tablet [**Hospital1 **]: 1-2 Tablets PO every 4-6 hours as +needed for nausea: crush & mix with water. . +Disp:*30 Tablet(s)* Refills:*0* +11. Ativan 1 mg Tablet [**Hospital1 **]: [**12-29**] - 1 Tablet PO every 4-6 hours as +needed for anxiety. +Disp:*30 Tablet(s)* Refills:*0* +12. Levofloxacin 500 mg Tablet [**Month/Day (2) **]: One (1) Tablet PO once a day +for 5 days. +Disp:*5 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] hospice care + +Discharge Diagnosis: +Primary Diagnosis +- Metastatic Esophageal CA +- Parapharyngeal Abcess +- Left Pleural Effusison +- Health-Care Acquired PNA + + +Discharge Condition: +good. Patient abulating. PEG in place. Tolerating +De-Cannulation. + + +Discharge Instructions: +You were admitted to hospital with shortness of [**Hospital 1440**] and +wheezing. You were found to have an infection in your throat for +which you received antibiotics. A breathing tracheostomy was +placed so that you were able to [**Hospital 1440**]. This infection was +treated and you are now able to breathe without the tube. The +hole in your neck should close up on its own, you do not need to +do anything about this. + +You were found to have a growning lesion in your left lung and +you underwent an operation to removed the lesion as well as +fluid. You were found to have recurrence of your esophageal +cancer. Dr. [**Last Name (STitle) **] will see you in clinic to discuss chemotherapy. + +You were also treated for a pneumonia. You need to take 5 more +days of an antibiotic called levofloxacin. + +Please continue to take all of your medications as listed below. +A number of changes have been made. + +Please keep all of your appointments. + +Please call your doctor if you experience continued fevers, +chills, shortness of [**Last Name (STitle) 1440**], chest pain, nausea, vomitting, +diarrhea. + +Followup Instructions: +With Dr. [**Last Name (STitle) 71392**] on [**1-30**] at 1:30 PM on [**Hospital Ward Name 23**] 9. + +Provider: [**First Name4 (NamePattern1) 1386**] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2131-1-25**] 12:45 +Provider: [**Name10 (NameIs) 4617**] [**Name8 (MD) **], [**MD Number(3) 1240**]:[**Telephone/Fax (1) 7976**] Date/Time:[**2131-1-26**] +2:15 +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 8268**], MD Phone:[**Telephone/Fax (1) 7976**] Date/Time:[**2131-1-29**] +10:30 + +Provider: [**Name10 (NameIs) **] [**Name8 (MD) 490**], MD, PHD[**MD Number(3) 708**]:[**0-0-**] +Date/Time:[**2131-2-8**] 9:00 + + + +",82,2130-12-04 19:01:00,2131-01-19 21:25:00,EMERGENCY,PHYS REFERRAL/NORMAL DELI,HOME HEALTH CARE,"ESOPHAGEAL MASS, NECK PAIN"," +the following summary is divided into sections due to the + ","PRIMARY: [Malignant neoplasm of cervical esophagus] +SECONDARY: [Perforation of esophagus; Secondary malignant neoplasm of lung; Malignant pleural effusion; Parapharyngeal abscess; Pneumonia, organism unspecified; Stricture and stenosis of esophagus; Unspecified disease of the jaws; Radiological procedure and radiotherapy as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Accidents occurring in other specified places; Anemia in neoplastic disease; Stenosis of larynx; Drug induced neutropenia; Penicillins causing adverse effects in therapeutic use; Accidents occurring in residential institution]" +85258,125297.0,29930,2131-06-11,29926,179741.0,2131-04-11,Discharge summary,"Admission Date: [**2131-3-26**] Discharge Date: [**2131-4-11**] + +Date of Birth: [**2090-5-18**] Sex: F + +Service: MEDICINE + +Allergies: +Roxicet + +Attending:[**First Name3 (LF) 477**] +Chief Complaint: +Stridor and fever. + +Major Surgical or Invasive Procedure: +Tracheostomy placemnt on [**2131-3-26**]. +Right subclavian line placement [**2131-3-28**]. +Right subvlacian line removal. + + +History of Present Illness: +This 40-year-old female has a long history of esophageal webs +and strictures. She was evaluated for this in the past and was +admitted in [**Month (only) **] with worsening dysphasia. She had an EGD on +[**2130-6-1**] that was successful on the third attempt and tissue +biopsy at that time revealed an invasive squamous cell +carcinoma. CT showed no evidence of metastases or local +invasion. She was started on Cetuximab with concurrent radiation +on [**2130-7-13**]. She completed her radiation therapy on [**2130-8-24**] +for a total of 6600 Gy. She also completed her Erbitux therapy +at that time. She was admitted on [**2130-12-4**] due to nausea and +vomiting. On that admission, she was found to have evidence of +tracheal obstruction. In addition, she had a CT of her neck, +which was concerning for perforation. Thoracic was consulted and +felt that she would benefit from a tracheostomy for airway +protection, which was placed on [**2130-12-8**]. She tolerated this +well. She was noted to have a left upper lobe cavitary lesion on +the CT scan. She underwent a wedge resection on [**2130-1-11**], which +revealed carcinomatous plaques on the pleural wall. This was +confirmed to be a metastatic disease on frozen section. In terms +of her tracheostomy, she was decannulated on [**2131-1-17**]. During +the hospitalization she was treated for pharyngeal abscess and +had issues with tachycardia as well as hypotension. She was +discharged home on [**2131-1-19**]. She began a palliative chemotherapy +regimen of 5-FU and carboplatin on [**2131-3-13**]. + +Past Medical History: +PAST ONCOLOGIC HISTORY (as previously documented on last +discharge summary dated [**3-18**]): +====================== +This 40-year-old female has a long history of esophageal webs +and strictures. She was evaluated for this in the past and was +admitted in [**Month (only) **] with worsening dysphasia. She had an EGD on +[**2130-6-1**] that was successful on the third attempt and tissue +biopsy at that time revealed an invasive squamous cell +carcinoma. CT showed no evidence of metastases or local +invasion. She was started on Cetuximab with concurrent radiation +on [**2130-7-13**]. She completed her radiation therapy on [**2130-8-24**] +for a total of 6600 Gy. She also completed her Erbitux therapy +at that time. She was admitted on [**2130-12-4**] due to nausea and +vomiting. On that admission, she was found to have evidence of +tracheal obstruction. In addition, she had a CT of her neck, +which was concerning for perforation. Thoracic was consulted and + +felt that she would benefit from a tracheostomy for airway +protection, which was placed on [**2130-12-8**]. She tolerated this +well. She was noted to have a left upper lobe cavitary lesion on + +the CT scan. She underwent a wedge resection on [**2130-1-11**], which +revealed carcinomatous plaques on the pleural wall. This was +confirmed to be a metastatic disease on frozen section. In terms + +of her tracheostomy, she was decannulated on [**2131-1-17**]. During +the hospitalization she was treated for pharyngeal abscess and +had issues with tachycardia as well as hypotension. She was +discharged home on [**2131-1-19**]. She began a palliative chemotherapy +regimen of 5-FU and carboplatin on [**2131-3-13**]. + +PAST MEDICAL HISTORY: +==================== +1. Esophageal strictures and webs. +2. Anemia. +3. G tube placed on 06/[**2129**]. +4. History of prior constipation. +5. Tracheostomy placed on [**2130-12-8**], removed on [**2131-1-17**] +6. Hypercalcemia + +Social History: +Originally from [**Country 3587**] and portugesse creole speaking only. + +EtOH: one +Tobacco: none +Lives at home with her cousin who cares for her. + + +Family History: +She has a maternal aunt with breast cancer. Her mother and +father are alive and healthy and siblings are all alive and +healthy. + +Physical Exam: +VITAL SIGNS - Temp 95.6 F, BP 101/35 mmHg, HR 122 BPM, RR 18 X', +O2-sat 96% RA +. +GENERAL - well-appearing woman in NAD, comfortable, appropriate +HEENT - NC/AT, PERRLA, EOMI, sclerae anicteric, MMM, OP clear +NECK - supple, no thyromegaly, no JVD, no carotid bruits +LUNGS - mild ronchi bilateraly, good air movement, resp +unlabored, no accessory muscle use +HEART - PMI non-displaced, RRR, no MRG, nl S1-S2, tachycardic +ABDOMEN - NABS, soft/NT/ND, no masses or HSM, no +rebound/guarding +EXTREMITIES - WWP, no c/c/e, 2+ peripheral pulses (radials, DPs) +SKIN - no rashes or lesions +LYMPH - no cervical, axillary, or inguinal LAD +NEURO - awake, A&Ox3, CNs II-XII grossly intact, muscle strength +[**5-1**] throughout, sensation grossly intact throughout, DTRs 2+ and +symmetric, cerebellar exam intact, steady gait + +Pertinent Results: +On Admission: +[**2131-3-26**] 12:00PM WBC-1.0* RBC-3.68* HGB-10.6* HCT-30.2* MCV-82 +MCH-28.9 MCHC-35.2* RDW-14.1 +[**2131-3-26**] 12:00PM PLT COUNT-209 +[**2131-3-26**] 12:00PM GRAN CT-140* +[**2131-3-26**] 12:00PM ALT(SGPT)-22 AST(SGOT)-28 LD(LDH)-181 ALK +PHOS-85 TOT BILI-0.4 +[**2131-3-26**] 12:00PM ALBUMIN-3.8 CALCIUM-10.1 PHOSPHATE-2.7 +MAGNESIUM-2.0 +[**2131-3-26**] 12:00PM UREA N-15 CREAT-0.5 SODIUM-136 POTASSIUM-3.9 +CHLORIDE-96 TOTAL CO2-31 ANION GAP-13 +[**2131-3-27**] 12:00AM PT-15.1* PTT-29.0 INR(PT)-1.3* +[**2131-3-27**] 12:00AM PLT SMR-NORMAL PLT COUNT-156 +. +Echocardiogram [**2131-3-28**]: +The left atrium is normal in size. No atrial septal defect is +seen by 2D or color Doppler. Left ventricular wall thickness, +cavity size and regional/global systolic function are normal +(LVEF >55%). There is no ventricular septal defect. Right +ventricular chamber size and free wall motion are normal. The +diameters of aorta at the sinus, ascending and arch levels are +normal. The aortic valve leaflets (3) appear structurally normal +with good leaflet excursion and no aortic regurgitation. No +masses or vegetations are seen on the aortic valve. The mitral +valve appears structurally normal with trivial mitral +regurgitation. No mass or vegetation is seen on the mitral +valve. The estimated pulmonary artery systolic pressure is +normal. There is no pericardial effusion. +. +CXR [**2131-4-26**]: +Portable AP chest radiograph was compared to [**2131-3-22**]. + +There is no significant change in the left basal consolidation +and at least partially loculated left pleural effusion including +the apical component. The right lung is essentially clear. The +mediastinal contours are unchanged. The postsurgical sutures in +the left upper lung are unchanged. There is a lucency projecting +over the left apical fluid collection that may represent small +loculated pneumothorax. The Port-A-Cath catheter tip is at the +cavoatrial junction. +The cavities in the right lung seen on the PET/CT from [**2131-3-8**] is difficult to see on both prior radiographs from [**3-22**] +and the current radiograph from [**2131-3-26**] that can be +either resolved or being below the limitations of the radiograph +resolution . If clinically warranted, further evaluation with +chest CT might be considered. +. +CT Abdomen/Pelvis [**2131-3-28**]: +1. Soft tissue density mass posterior to the tracheostomy +catheter was seen on prior CT scan and is consistent with +patient's metastatic esophageal cancer. +2. Multiple right-sided right lung as well as right pleural +nodules concerning for progression of metastatic disease on that +side. +3. Overall stable appearance to extensive pleural as well as +parenchymal metastatic disease in the left lung. Nodular foci in +the right and left lungs, however, could also represent foci of +infectious process and would recommend followup to assess for +change or resolution. +. +CT Neck: +Ill-defined soft tissue associated with the esophagus in the +post-cricoid region and hypopharynx in the area of prior FDG +avidity. Lack of soft tissue delineation limits ability to fully +evaluate. + +Brief Hospital Course: +40 yo F with metastatic esophageal carcinoma s/p recent +initiation of carboplatin and 5fu, s/p trach in past, admitted +to oncology with febrile neutropenia and transferred for +concerning increased stridor and narrowed airway. +. +## Stridor: Patient with history of stridor in past, leading to +trach in [**10-25**] for esophageal perforation possibly in +setting of nausea/vomiting and laryngeal edema. Recent PET scan +with increased uptake in this area. Based on ENT evaluation, +patient's airway narrowed to 1-2 mm. Area of concern from prior +imaging was in cervical esophagus, so would be above area of +possible trach. Pt received IV decadron without improvement. Her +respiratory rate increased, there was use of accesory muscles so +she was tranferred to the ICU. She was evaluated by thoracic +surgeons who took her emergently to the OR for trach placement +with heliox given prior. After the procedure she continued to +spike fever, was tachycardic, was acutely dropping her oxygen +sats. She had an emergent bronch which showed patent airways. +She initally had difficulty weaning from the vent. She was +weaned to trach collar on [**3-31**]. Since then she has been stable in +the floor breathing in 35% humidified air via a tracheal mask. +She was trainned in multiple days to use her tracheostoy and how +to release the inner canula. She was able to do it by herself +every single day afterwards. +. +# Neutropenic fever/sepsis: Patient spiking fevers to 101 on +cefepime on the floor. She also spiked fever subsequently after +coming back from the OR. Overnight her first night in the ICU +her antibiotics were broadended to clinda, cefepime, flagyl, +vanco, and ceftriaxone. She also dropped her pressures and was +started on levo (weaned off on [**3-29**]) and boluses IVF to maintain +a MAP> 65 and a CVP>10. On the morning of [**3-28**] these were +changed to clinda/vanc/cefepime. Her fevers resolved and her +clindamycin was d/c after 6 doses. She was continued on +filgrastim and was no longer neutropenic as of [**2131-3-31**]. The plan +was to continue a 10 day course of vanc/cefepime with day 1 +being [**3-31**] and her last dose being [**2131-4-9**]. However, cefepime +will not be covered by her insurance so we started ciprofloxacin +instead on [**4-4**] and we recommend two days of treatment on cipro +and then discontinuing the cipro. She compleated the antibiotic +course in house and was afebrile afterwards. +. +# Sinus tachy: has been ongoing issue per last discharge +summary, has been ranging in 120s in past, is of unknown +etiology. Has been persistent despite fluid resuscitation, +transfusion, and correction of hypercalcemia in past. EKGs sinus +tachycardia. Her sinus tachycardia did not respond to fluid +resuscitation in the ICU. It is possible that this could be +secondary to vagus nerve infiltration of her tumor, leading to +unopposed sympathetic stimulation. +. +# Metastatic esophageal cancer: with mets to lungs, recent PET +scan showed increased disease in lung, upper esophagus, and +paratracheal region. Has been recently reinitiated on +carboplatin and 5FU about 1 week prior to being in the ICU. As +per family meetings while in the ICU, the plan is to give her 2 +week holiday and then assess and consider palliative +chemotherapy. +. +# HCT: Pt received 2 units of packed RBCs for HCT of 23 and +bumped appropriately. She has not required blood transfusion +since [**3-29**]. +. +# Left flank/back pain: Likely secondary to mets. At home on +lidocaine, methadone, tylenol. Methadone was restarted on [**3-29**]. +. +# FEN/GI: Pt getting tube feeds started on [**3-30**]. S & S saw pt +and is ok to get ice chips, but pt was unable to tolerate +liquids. She will need to be strict NPO. +. +# PROPHY: sc heparin, bowel regimen , PPI. +. +# ACCESS: right portacath, left PIV, CVL. An a-line was put in +while in the ICU and d/c while in the ICU. +. +# Dispo: Home with free hospice. + +Medications on Admission: +1. Lactulose 10 gram/15 mL Syrup [**Month/Day (4) **]: Thirty (30) ML PO Q8H +(every 8 hours) as needed for constipation: through j tube. +2. Lorazepam 0.5 mg Tablet [**Month/Day (4) **]: 1-2 Tablets PO Q6H (every 6 +hours) as needed for anxiety/nausea: through j tube. +3. Methadone 5 mg Tablet [**Month/Day (4) **]: 1-2 Tablets PO BID (2 times a +day). +4. Nortriptyline 10 mg Capsule [**Month/Day (4) **]: One (1) Capsule PO HS (at +bedtime). +5. Omeprazole-Sodium Bicarbonate 40-1,680 mg Packet [**Month/Day (4) **]: One (1) + +PO once a day: through j tube. +6. Prochlorperazine 25 mg Suppository [**Month/Day (4) **]: One (1) Rectal every + +six (6) hours as needed for nausea. +7. Acetaminophen 160 mg/5 mL Solution [**Month/Day (4) **]: [**12-29**] PO every six (6) + +hours as needed for pain. +8. Bisacodyl 10 mg Suppository [**Month/Day (2) **]: One (1) Suppository Rectal 1 + +to 2 times per day as needed for constipation. +9. Docusate Sodium 50 mg/5 mL Liquid [**Month/Day (2) **]: 10mL PO BID (2 times +a day). +10. Senna 8.8 mg/5 mL Syrup [**Month/Day (2) **]: One (1) PO twice a day. +11. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated [**Month/Day (2) **]: +Three (3) Adhesive Patch, Medicated Topical DAILY (Daily): apply + +to left side for no more than 12 hours at a time. +12. Guaifenesin 100 mg/5 mL Syrup [**Month/Day (2) **]: Fifteen (15) ML PO Q6H +(every 6 hours) as needed. + + +Discharge Medications: +1. Oxygen +35% continuous via tracheal mask with cool mist via [**Last Name (un) **] +compressor. +2. Suction Machine +Please provide with portable suction machine with trach suction +catheter size 14 fr. +3. Trach +Please provide with 6mm portex for tracheostomy. +4. Oxygen +Please provide with oxygen tanks at home for tracheostomy +humidifier at 35%. Respiratory diangosisL Esophageal cancer with +laringeal involvement. Lowest SpO2 90% on RA. [**Medical Record Number 71505**]. +5. Methadone 10 mg/5 mL Solution [**Medical Record Number **]: Five (5) mililiters PO PM +(). +6. Methadone 10 mg/5 mL Solution [**Medical Record Number **]: 2.5 mililiters PO AM (). +7. Lorazepam 0.5 mg Tablet [**Medical Record Number **]: 1-2 Tablets PO Q4H (every 4 +hours) as needed for anxiety. +8. Lactulose 10 gram/15 mL Syrup [**Medical Record Number **]: Thirty (30) ML PO BID (2 +times a day). +9. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] DAILY (Daily). +Disp:*30 Tablet,Rapid Dissolve, DR(s)* Refills:*2* +10. Nortriptyline 10 mg/5 mL Solution [**Last Name (STitle) **]: Five (5) mililiters +PO at bedtime as needed for insomnia. +Disp:*1 Liter* Refills:*0* +11. Compazine 25 mg Suppository [**Last Name (STitle) **]: One (1) Suppository Rectal +every six (6) hours as needed for nausea. +Disp:*30 Suppository* Refills:*0* +12. Acetaminophen 167 mg/5 mL Liquid [**Last Name (STitle) **]: [**5-6**] Mililiters PO +every six (6) hours as needed for Pain. +Disp:*500 mililiters* Refills:*0* +13. Lidocaine 5 %(700 mg/patch) Adhesive Patch, Medicated [**Month/Year (2) **]: +One (1) Adhesive Patch, Medicated Topical Q12H (every 12 hours): +12 hours on, 12 hours off. +Disp:*30 Adhesive Patch, Medicated(s)* Refills:*2* +14. Guaifenesin 100 mg/5 mL Syrup [**Month/Year (2) **]: 5-10 MLs PO Q6H (every 6 +hours) as needed for cough, throat pain. +Disp:*250 ML(s)* Refills:*0* +15. Morphine 10 mg/5 mL Solution [**Month/Year (2) **]: Five (5) Mililiters PO Q4H +(every 4 hours) as needed for pain. +Disp:*250 Mililiters* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital 269**] Hospice Care + +Discharge Diagnosis: +Primary Diagnosis: +Respiratory Distress/Failure secondary to either chemical +irritation of the airway or esophageal cancer infiltration to +the esophagus. +. +Secondary Diagnosis: +Esophageal strictures and webs. +Anemia. +G tube placed on [**5-/2130**] + + +Discharge Condition: +Stable, cleaning her tracheostomy herslef, walking miles in the +corridor. + + +Discharge Instructions: +You were seen at the [**Hospital1 18**] for neutropenic fever after your +chemotherapy. Upon arrival you mentioned that you had been +having difficulty breathing during the last days. It started to +get worse during the course of the first hospital day. You were +seen by the ENT, who saw a very narrow arway. Since your +breathing started getting worse and we were unable to help you +breathe a tracheostomy was put in place. You required ICU stay. +Then, you were transfered to the medical floor where you were +observed. Your tube feedings were re-started. You were evaluated +by speech and swallow, but everytime you had any liquids you +started coughing and there is risk of aspiration and +food/liquids going down the wrong pipe. Therefore we recommend +you do not drink or eat anything by mouth, but everything +through your J tube. +. +Dr. [**Last Name (STitle) **] saw you and recommended 2 weeks at home and then meet +with him so you all can talk regarding how to keep helping you +with your cancer. +. +We were able to set up free hospice at home, where you will have +a tem that will help you with your feeding tubes, tracheostomy, +pain and transition for better control of your symptoms. +. +If you have fever, chills, cough, difficulty breathing, +worsening of your pain or anything else that concerns you please +come back to our ER. + +Followup Instructions: +Please make an appointment with Dr. [**Last Name (STitle) **] within 2 weeks. You can +call ([**Telephone/Fax (1) 694**]. +. +[**2131-4-17**] 02:30p Dr [**Last Name (STitle) 1533**] in the THORACIC CLINIC to +remove the stitches of your tracheostomy. + + + [**Name6 (MD) **] [**Name8 (MD) 490**] MD, [**MD Number(3) 491**] + +",61,2131-03-26 18:16:00,2131-04-11 20:40:00,EMERGENCY,CLINIC REFERRAL/PREMATURE,HOSPICE-HOME,NEUTROPENIA;ESOPHEGEAL CANCER," +40 yo f with metastatic esophageal carcinoma s/p recent +initiation of carboplatin and 5fu, s/p trach in past, admitted +to oncology with febrile neutropenia and transferred for +concerning increased stridor and narrowed airway. +. +## stridor: patient with history of stridor in past, leading to +trach in [**10-25**] for esophageal perforation possibly in +setting of nausea/vomiting and laryngeal edema. recent pet scan +with increased uptake in this area. based on ent evaluation, +patients airway narrowed to 1-2 mm. area of concern from prior +imaging was in cervical esophagus, so would be above area of +possible trach. pt received iv decadron without improvement. her +respiratory rate increased, there was use of accesory muscles so +she was tranferred to the icu. she was evaluated by thoracic +surgeons who took her emergently to the or for trach placement +with heliox given prior. after the procedure she continued to +spike fever, was tachycardic, was acutely dropping her oxygen +sats. she had an emergent bronch which showed patent airways. +she initally had difficulty weaning from the vent. she was +weaned to trach collar on [**3-31**]. since then she has been stable in +the floor breathing in 35% humidified air via a tracheal mask. +she was trainned in multiple days to use her tracheostoy and how +to release the inner canula. she was able to do it by herself +every single day afterwards. +. +# neutropenic fever/sepsis: patient spiking fevers to 101 on +cefepime on the floor. she also spiked fever subsequently after +coming back from the or. overnight her first night in the icu +her antibiotics were broadended to clinda, cefepime, flagyl, +vanco, and ceftriaxone. she also dropped her pressures and was +started on levo (weaned off on [**3-29**]) and boluses ivf to maintain +a map> 65 and a cvp>10. on the morning of [**3-28**] these were +changed to clinda/vanc/cefepime. her fevers resolved and her +clindamycin was d/c after 6 doses. she was continued on +filgrastim and was no longer neutropenic as of [**2131-3-31**]. the plan +was to continue a 10 day course of vanc/cefepime with day 1 +being [**3-31**] and her last dose being [**2131-4-9**]. however, cefepime +will not be covered by her insurance so we started ciprofloxacin +instead on [**4-4**] and we recommend two days of treatment on cipro +and then discontinuing the cipro. she compleated the antibiotic +course in house and was afebrile afterwards. +. +# sinus tachy: has been ongoing issue per last discharge +summary, has been ranging in 120s in past, is of unknown +etiology. has been persistent despite fluid resuscitation, +transfusion, and correction of hypercalcemia in past. ekgs sinus +tachycardia. her sinus tachycardia did not respond to fluid +resuscitation in the icu. it is possible that this could be +secondary to vagus nerve infiltration of her tumor, leading to +unopposed sympathetic stimulation. +. +# metastatic esophageal cancer: with mets to lungs, recent pet +scan showed increased disease in lung, upper esophagus, and +paratracheal region. has been recently reinitiated on +carboplatin and 5fu about 1 week prior to being in the icu. as +per family meetings while in the icu, the plan is to give her 2 +week holiday and then assess and consider palliative +chemotherapy. +. +# hct: pt received 2 units of packed rbcs for hct of 23 and +bumped appropriately. she has not required blood transfusion +since [**3-29**]. +. +# left flank/back pain: likely secondary to mets. at home on +lidocaine, methadone, tylenol. methadone was restarted on [**3-29**]. +. +# fen/gi: pt getting tube feeds started on [**3-30**]. s & s saw pt +and is ok to get ice chips, but pt was unable to tolerate +liquids. she will need to be strict npo. +. +# prophy: sc heparin, bowel regimen , ppi. +. +# access: right portacath, left piv, cvl. an a-line was put in +while in the icu and d/c while in the icu. +. +# dispo: home with free hospice. + + ","PRIMARY: [Drug induced neutropenia] +SECONDARY: [Malignant neoplasm of other specified part of esophagus; Other specified septicemias; Sepsis; Acute respiratory failure; Fever presenting with conditions classified elsewhere; Antineoplastic and immunosuppressive drugs causing adverse effects in therapeutic use; Stricture and stenosis of esophagus; Anemia in neoplastic disease; Dehydration; Stridor; Backache, unspecified]" +85258,125297.0,29930,2131-06-11,29853,122457.0,2131-01-19,Discharge summary,"Admission Date: [**2130-12-4**] Discharge Date: [**2131-1-19**] + +Date of Birth: [**2090-5-18**] Sex: F + +Service: MEDICINE + +Allergies: +Roxicet + +Attending:[**First Name3 (LF) 4057**] +Chief Complaint: +Nausea, Vomiting + +Major Surgical or Invasive Procedure: +Tracheostomy +thoracentesis +Left VATS +Mechanical Ventilation + + +History of Present Illness: +40 yo F with unresectable esophageal cancer who was recently +discharged from the hospital secondary to right neck pain. She +was then discharged on [**12-1**]. Notes indicate the patient +re-presented on [**12-4**] with the chief complaint of ""strange +sounding airway"" and dyspnea. She was found to have a soft +tissue infection lateral to the esophagus that likely represents +microperforation, for which she was started on abx, and she +required surgical tracheostomy for upper airway obstruction +caused by her esophageal cancer. +. +Additionally, her MICU course was remarkable for persistent +tachycardia and mild hypotension. Her heart rate remains 120s at +rest with brief episodes of rates as high as 150 when she is out +of bed, sinus tachycardia at all times. Her blood pressure has +ranged from 70s-90s systolic, which does not appear to be new, +as OMR notes document systolic blood pressures in the high +80s-low 90s at multiple visits. Evaluation as to the cause of +tachycardia has included TSH (low normal), with fT4 pending; +echo (nml LV and RV function, no echocardiographic signs of +hemodynamically significant PE); ABG 7.46/41/114 was with pt +breathing room air for 10 minutes, indicating that there is no +apparent A-a gradient; a random cortisol level was low, but +responded appropriately to cosyntropin. Since she appears well, +with good skin turgor and adequate urine output, despite the +tachycardia and hypotension, she was transferred out of the ICU. + + + +Past Medical History: +#. Invasive Esophageal Squamous Squamous Cell Carcinoma: +- [**2129-11-1**]: Pt arrived in America from [**Country 3587**] +- [**2129-11-2**]: Pt evaluated for Odynophagia, tx with Prilosec +- 11/26-30/07: Admitted fo Esophageal Web Dilations that +relieved symptoms +- [**1-4**]: Symptoms of odynophagia returned +- [**2130-2-12**]: Referred to ENT for recurrent cervial web at C4-5 +- [**2130-4-14**]: Esophageal Dilation under general anesthesia +- [**5-4**]: ENT consult for bilateral submandibular pain +- 5/29-30/08: Two subsequent attempts at dilation unsucessful +- [**6-4**]: PEG placed for FTT +- [**2130-6-7**]: Bx confirms Invasive Squamous Cell CA +- [**2130-6-20**]: +diagnosed [**2130-5-28**] in +setting of esophageal stricture +- high cervical esophageal lesion not resectable +- completed therapy with Cetuximab and radiation therapy +# Anemia +# Upper esophageal and pharyngeal stricture; s/p PEG +# Shoulder Pain +# Lung lesion - NOS +# Chronic pain from radiation. +# Nausea and vomiting. +# PEG tube site candidiasis + + +Social History: +The patient lives in [**Location 686**], MA with her cousin [**Name (NI) **] [**Name (NI) **], +who is her HCP. The patient is initially from [**Country 11660**] +islands, she is not currently working. +Tobacco: None +ETOH: None +Illicits: None + + +Family History: +There is no history in her family of heart disease, gastric +cancer, esophageal cancer or colon cancer or inflammatory bowel +disease. + + +Physical Exam: +ADMISSION PHYSICAL EXAM +VS: T = 99.4 P = 120 BP = 108/60 RR 16, O2Sat:100% +GENERAL: Young female who appears older than her stated age. +She is appears tired and worn. +Mentation: Alert but restricted affect. Does not smile. +Eyes:NC/AT, PERRL, EOMI without nystagmus, no scleral icterus +noted +Ears/Nose/Mouth/Throat: MMM, no lesions noted in OP +Neck: supple, no JVD or carotid bruits appreciated +Respiratory: Bibasilar crackles +Cardiovascular: tachy, nl. S1S2, no M/R/G noted +Gastrointestinal: soft, NT/ND, normoactive bowel sounds, no +masses or organomegaly noted. +PEG site C/D/I no odor. Appears better than during previous +admission. +Genitourinary: +Skin: no rashes or lesions noted. No pressure ulcer +Extremities: No C/C/E bilaterally, 2+ radial, DP and PT pulses +b/l. +Lymphatics/Heme/Immun: No cervical lymphadenopathy noted. +Neurologic: +-mental status: Alert, oriented x 3. Able to relate history +without difficulty. +-cranial nerves: II-XII intact +-motor: normal bulk, strength and tone throughout. No abnormal +movements noted. +-DTRs: 2+ biceps, triceps, +No foley catheter/tracheostomy/PEG/ventilator support/chest +tube/colostomy +Psychiatric: Very limited affect with rare brightening. +. +PHYSICAL EXAM UPON ARRIVAL TO THE FLOOR: [**12-11**] +Vitals: T97.9 BP96/50 HR126 RR19 O2Sat100% on 35% trach collar +GEN: Thin, tired-appearing [**Location 7972**] woman +HEENT: EOMI, PERRL, sclera anicteric, no epistaxis or +rhinorrhea, MMM, OP Clear +NECK: No JVD, carotid pulses brisk, no bruits, no cervical +lymphadenopathy, trachea with sutured trach cannula +COR: tachy, no M/G/R, normal S1 S2, radial pulses +2 +PULM: bronchial [**Location 1440**] sounds throughout +ABD: Soft, NT, ND, +BS, no HSM, no masses. PEG in place in LUQ +EXT: No C/C/E, no palpable cords +NEURO: alert, oriented to person, place, and time. CN II ?????? XII +grossly intact. Moves all 4 extremities. Strength 5/5 in upper +and lower extremities. Patellar DTR +1. Plantar reflex +downgoing. No gait disturbance. No cerebellar dysfunction. +SKIN: Normal turgor. No jaundice, cyanosis, or gross dermatitis. +No ecchymoses. + +Pertinent Results: +[**2130-12-4**] Neck CT: +1. No mass lesions are detected within the airway to explain +stridorous +breathing. +2. Fluid again noted within the esophagus in the region of the +thyroid gland. Also noted on prior study, possibly relating to +region of stricture. +3. Slight increase in cavitary lesion within the left lung apex. + + +NOTE ADDED AT ATTENDING REVIEW: There is a collection of air in +the right +neck, apparently just lateral to the esophagus, but possibly +within a dilated esophagus, best seen on images 34-37 of series +2. In this location it raises the possibility of an esophageal +perforation. Since it is difficult to determine the location of +the lateral margin of the esophagus, it is difficult to +distinguish an extraluminal collection from dilatation of the +organ. An MR examination may be helpful. + +There is induration of the adjacent tissues, which could be a +consequence of local infection, but also could arise as a result +of prior radiation. +. +[**2130-12-4**] CT CHEST +1. Small pharyngeal or paralaryngeal abscess, phlegmon or +malignancy has +grown over two weeks. If the lesion is inflammatory it suggests +ulceration in the hypopharynx/upper esohagus. Please see report +of today's neck CT. +2. Slow growth of small left upper lobe lung cavity and a tiny +right lower +lobe lesion as well as a new left lower lobe lesion are +concerning for +multifocal metastases, or slow spread of an indolent infection. +Small growing +left pleural mass is more characteristic of metastasis. +. +[**2130-12-6**] MRI SOFT TISSUE NECK, W/O & W/CONTRAST +IMPRESSION: 12 x 8 mm collection of air with small amount of +fluid just +anterior to the right aspect of the esophagus at the level of +the thyroid +gland which likely represents esophageal perforation and/or +abscess. +Additional considerations include esophageal diverticulum, +although less +likely. +. +TTE (Complete) Done [**2130-12-11**] at 2:38:57 PM +Conclusions +The left atrium is normal in size. No atrial septal defect is +seen by 2D or color Doppler. The estimated right atrial pressure +is 0-5 mmHg. Left ventricular wall thickness, cavity size and +regional/global systolic function are normal (LVEF >55%). There +is no ventricular septal defect. Right ventricular chamber size +and free wall motion are normal. The aortic valve leaflets (3) +appear structurally normal with good leaflet excursion and no +aortic regurgitation. The mitral valve appears structurally +normal with trivial mitral regurgitation. The estimated +pulmonary artery systolic pressure is normal. There is no +pericardial effusion. +Compared with the prior study (images reviewed) of [**2130-2-28**], no +change. +. +[**2130-12-12**] CTA CHEST +1. No pulmonary embolism. +2. New left posterior pleural lesion. Although this would be an +atypical +location for an esophageal carcinoma metastasis, the possibility +of malignancy cannot be totally excluded and PET CT may provide +additional diagnostic information. +3. Increase in right lower lobe and left upper lobe opacities +and new left +lower lobe opacity most likely represent infectios process; from +the same or different [**Doctor Last Name 360**] +4. Resolution of fluid collection in the posterior +parapharyngeal space +compared to the CT of [**2130-12-4**]., now fluid filled +. +[**2130-12-17**] CXR +Tracheostomy tube is again visualized. There is new left small +pleural effusion with volume loss in the left lower lobe. An +early infiltrate in this region cannot be totally excluded. +Otherwise, the lungs are clear. +. +LABWORK: +[**2130-12-4**] 08:42PM GLUCOSE-112* UREA N-13 CREAT-0.5 SODIUM-133 +POTASSIUM-5.0 CHLORIDE-92* TOTAL CO2-29 ANION GAP-17 +[**2130-12-4**] 08:42PM estGFR-Using this +[**2130-12-4**] 08:42PM HCG-<5 +[**2130-12-4**] 08:42PM CALCIUM-9.2 PHOSPHATE-2.4* MAGNESIUM-2.0 +[**2130-12-4**] 08:42PM WBC-9.6 RBC-3.35* HGB-9.8* HCT-28.8* MCV-86 +MCH-29.2 MCHC-34.0 RDW-14.7 +[**2130-12-4**] 08:42PM NEUTS-81.3* LYMPHS-12.0* MONOS-5.8 EOS-0.8 +BASOS-0.1 +[**2130-12-4**] 08:42PM PLT COUNT-672* +[**2130-12-4**] 08:42PM PT-14.3* PTT-25.5 INR(PT)-1.2* +. +Hematology + COMPLETE BLOOD COUNT WBC RBC Hgb Hct MCV MCH MCHC RDW Plt Ct +[**2131-1-19**] 12:00AM + 4.8 3.02* 9.5* 26.6* 88 31.4 35.8* 13.4 377 +Source: Line-PICC +[**2131-1-18**] 12:00AM + 4.7 3.14* 9.5* 26.8* 85 30.4 35.6* 13.9 356 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM + 5.4 3.38* 10.2* 29.4* 87 30.1 34.6 13.8 368 +Source: Line-PICC +[**2131-1-16**] 12:00AM + 4.0 3.51* 10.6* 30.7* 88 30.2 34.6 14.0 359 +Source: Line-PICC +[**2131-1-15**] 02:04AM + 5.0 3.17* 9.5* 26.8* 85 30.0 35.5* 14.8 352 +Source: Line-arterial +[**2131-1-14**] 04:41AM + 7.8 3.28* 10.2* 27.7* 84 31.1 36.9* 14.6 358 +Source: Line-arterial +[**2131-1-13**] 10:21PM + 10.6 3.44*# 10.9*# 29.0*#1 84 31.6 37.5* 14.0 425 +Source: Line-arterial +[**2131-1-13**] 02:24AM + 7.3 2.70* 8.2* 23.1* 85 30.4 35.6* 14.3 415 +Source: Line-aline +[**2131-1-12**] 06:20PM + 7.4# 2.71* 8.1* 23.2* 86 30.1 35.1* 14.3 356 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 4.2 2.93* 8.8* 25.7* 88 29.9 34.1 13.9 389 +[**2131-1-10**] 05:45AM + 3.7* 3.08* 9.1* 26.7* 87 29.6 34.2 13.9 420 +[**2131-1-9**] 06:15AM + 3.7* 3.09* 9.2* 26.3* 85 29.9 35.2* 14.0 430 +[**2131-1-8**] 05:35AM + 3.9* 3.26* 9.8* 28.2* 87 30.1 34.8 13.9 431 +[**2131-1-6**] 05:40AM + 3.3* 3.24* 9.8* 27.5* 85 30.4 35.8* 14.5 409 +[**2131-1-5**] 07:20AM + 3.2* 3.24* 10.1* 28.1* 87 31.1 35.9* 14.4 386 +[**2131-1-4**] 06:30AM + 3.4* 3.60* 11.0* 31.1* 86 30.6 35.5* 14.5 431 +[**2131-1-3**] 01:45PM + 4.3# 3.70* 11.3* 32.2* 87 30.6 35.1* 14.5 441* +[**2131-1-2**] 07:45AM + 2.5* 3.06* 9.1* 27.2* 89 29.7 33.5 14.5 363 +[**2131-1-1**] 06:50AM + 2.4* 3.11* 9.3* 27.0* 87 29.8 34.4 14.6 386 +[**2130-12-31**] 05:50AM + 2.2* 3.11* 9.3* 27.2* 88 29.9 34.2 14.3 372 +[**2130-12-30**] 06:00AM + 2.3* 3.26* 9.9* 29.0* 89 30.4 34.2 13.9 376 +[**2130-12-29**] 06:45AM + 2.1* 3.07* 9.2* 27.1* 88 29.8 33.8 13.8 344 +[**2130-12-28**] 05:55AM + 2.1* 3.17* 9.7* 28.2* 89 30.7 34.6 14.6 381 +[**2130-12-27**] 10:00AM + 2.0* 3.19* 9.6* 28.2* 88 29.9 33.9 14.5 420 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM + 1.7* 3.10* 9.8* 27.5* 89 31.5 35.6* 13.9 320 +[**2130-12-25**] 06:15AM + 2.3* 2.92* 8.9* 25.3* 87 30.4 35.1* 13.9 340 +[**2130-12-24**] 05:50AM + 2.7* 2.97* 9.1* 25.4* 86 30.6 35.8* 14.7 331 +[**2130-12-22**] 05:35AM + 2.7* 2.98* 8.8* 26.2* 88 29.4 33.5 14.9 337 +[**2130-12-21**] 06:00AM + 2.4* 3.03* 9.2* 26.6* 88 30.4 34.6 14.4 303 +[**2130-12-20**] 05:50AM + 2.3* 3.00* 8.9* 25.8* 86 29.7 34.5 15.3 308 +[**2130-12-19**] 07:00AM + 3.0* 3.30* 10.1* 29.2* 89 30.5 34.5 15.3 302 +[**2130-12-16**] 09:05AM + 3.4* 3.46*# 10.3*# 30.0* 87 29.9 34.5 15.9* 327 +[**2130-12-15**] 03:35PM 29.9* +[**2130-12-14**] 07:40AM + 5.4 2.75* 8.2* 24.6* 90 29.8 33.3 15.7* 358 +[**2130-12-13**] 08:00AM + 9.0 2.99* 9.0* 26.0* 87 30.1 34.7 15.6* 378 +[**2130-12-12**] 07:45AM 6.0 2.92* 8.7* 25.7* 88 29.9 34.0 15.3 387 +[**2130-12-11**] 04:22AM 6.9 2.97* 8.9* 26.1* 88 30.0 34.1 15.3 415 +[**2130-12-10**] 04:26AM + 8.4 3.08* 9.1* 26.7* 87 29.4 33.9 15.1 457* +[**2130-12-9**] 04:54AM + 9.1 2.88* 8.8* 25.0* 87 30.6 35.3* 15.1 466* +[**2130-12-8**] 06:10AM + 7.0 3.10* 9.0* 26.8* 87 29.1 33.6 14.6 514* +[**2130-12-7**] 03:47AM + 12.8*# 3.43* 10.4* 30.3* 88 30.2 34.2 15.2 645* +[**2130-12-6**] 03:18AM + 7.9 3.23* 9.7* 27.8* 86 30.2 35.0 15.0 633* +[**2130-12-5**] 10:00AM + 7.4 3.19* 9.1* 27.9* 87 28.4 32.5 15.2 553* +[**2130-12-4**] 08:42PM + 9.6 3.35* 9.8* 28.8* 86 29.2 34.0 14.7 672* + +VERIFIED LABEL + +D +IFFERENTIAL Neuts Bands Lymphs Monos Eos Baso Atyps Metas Myelos +[**2131-1-12**] 06:20PM 89.5* 6.6* 2.6 1.2 0 +Source: Line-arterial ulnar +[**2131-1-6**] 05:40AM 57 2 20 13* 4 0 2* 1* 1* +[**2131-1-5**] 07:20AM 60.3 21.8 10.3 7.5* 0.1 +[**2131-1-4**] 06:30AM 62.9 25.3 7.3 4.4* 0.2 +[**2131-1-3**] 01:45PM 70.2* 16.9* 7.7 5.1* 0.1 +[**2131-1-1**] 06:50AM 53.0 27.4 10.5 8.7* 0.4 +[**2130-12-31**] 05:50AM 56 0 36 4 1 0 3* 0 0 +[**2130-12-30**] 06:00AM 39.8* 42.9* 11.6* 5.4* 0.3 +[**2130-12-29**] 06:45AM 45.6* 32.4 13.0* 8.7* 0.3 +[**2130-12-28**] 05:55AM 27* 3 56* 9 3 0 2* 0 0 +[**2130-12-27**] 10:00AM 31* 0 40 18* 10* 1 0 0 0 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 52.8 28.4 9.4 8.8* 0.6 +[**2130-12-25**] 06:15AM 50 0 28 14* 5* 2 1* 0 0 +[**2130-12-21**] 06:00AM 51.6 34.1 8.6 5.4* 0.3 +[**2130-12-8**] 06:10AM 84.1* 9.3* 5.7 0.7 0.1 +[**2130-12-4**] 08:42PM 81.3* 12.0* 5.8 0.8 0.1 + RED CELL +M +O +R +P +H +O +L +O +G +Y Hypochr Anisocy Poiklo Macrocy Microcy Polychr Ovalocy Schisto +[**2131-1-6**] 05:40AM + NORMAL1 1+ 1+ NORMAL 1+ OCCASIONAL 1+ OCCASIONAL + +NORMAL +MANUALLY COUNTED + BASIC COAGULATION (PT, PTT, PLT, INR) PT PTT Plt Smr Plt +Ct INR(PT) +[**2131-1-19**] 12:00AM 377 +Source: Line-PICC +[**2131-1-18**] 12:00AM 356 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 368 +Source: Line-PICC +[**2131-1-16**] 12:00AM 359 +Source: Line-PICC +[**2131-1-15**] 02:04AM 352 +Source: Line-arterial +[**2131-1-14**] 04:41AM 358 +Source: Line-arterial +[**2131-1-13**] 10:21PM 425 +Source: Line-arterial +[**2131-1-13**] 02:24AM 415 +Source: Line-aline +[**2131-1-12**] 06:20PM 356 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 389 +[**2131-1-12**] 01:00AM 14.5* 28.3 1.3* +[**2131-1-10**] 05:45AM 420 +[**2131-1-9**] 06:15AM 430 +[**2131-1-8**] 05:35AM 431 +[**2131-1-6**] 05:40AM NORMAL 409 +[**2131-1-5**] 07:20AM 386 +[**2131-1-4**] 06:30AM 431 +[**2131-1-3**] 01:45PM 441* +[**2131-1-3**] 01:45PM 13.0 27.7 1.1 +[**2131-1-2**] 07:45AM 363 +[**2131-1-1**] 06:50AM 386 +[**2130-12-31**] 05:50AM NORMAL 372 +[**2130-12-30**] 06:00AM 376 +[**2130-12-29**] 06:45AM 344 +[**2130-12-28**] 05:55AM 381 +[**2130-12-27**] 10:00AM NORMAL 420 +SPECIMNE ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 320 +[**2130-12-25**] 06:15AM NORMAL 340 +[**2130-12-24**] 05:50AM 331 +[**2130-12-22**] 05:35AM 337 +[**2130-12-21**] 06:00AM 303 +[**2130-12-20**] 05:50AM 308 +[**2130-12-19**] 07:00AM 302 +[**2130-12-16**] 09:05AM 327 +[**2130-12-14**] 07:40AM 358 +[**2130-12-13**] 08:00AM 378 +[**2130-12-12**] 07:45AM 387 +[**2130-12-11**] 04:22AM 415 +[**2130-12-10**] 04:26AM 457* +[**2130-12-9**] 04:54AM 466* +[**2130-12-8**] 06:10AM 514* +[**2130-12-8**] 04:25AM 17.0* 29.6 1.5* +[**2130-12-7**] 03:47AM 645* +[**2130-12-6**] 03:18AM 633* +[**2130-12-5**] 10:00AM 553* +[**2130-12-4**] 08:42PM 672* +[**2130-12-4**] 08:42PM 14.3*1 25.5 1.2* + +HEMOLYZED, MODERATELY +INTERPRET RESULTS WITH CAUTION +Chemistry + RENAL & GLUCOSE Glucose UreaN Creat Na K Cl HCO3 AnGap +[**2131-1-19**] 12:00AM 99 15 0.4 134 4.6 96 29 14 +Source: Line-PICC +[**2131-1-18**] 12:00AM 96 17 0.4 140 4.6 102 29 14 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 96 12 0.4 133 4.4 97 27 13 +Source: Line-PICC +[**2131-1-16**] 12:00AM 129* 7 0.4 133 4.5 95* 28 15 +Source: Line-PICC +[**2131-1-15**] 02:04AM 129* 7 0.4 138 3.6 105 26 11 +Source: Line-arterial +[**2131-1-14**] 04:41AM 160* 5* 0.5 137 4.2 104 25 12 +Source: Line-arterial +[**2131-1-13**] 10:21PM 192* 5* 0.4 135 3.6 100 27 12 +Source: Line-arterial +[**2131-1-13**] 02:24AM 87 4* 0.4 133 3.9 102 27 8 +Source: Line-aline +[**2131-1-12**] 06:20PM 99 5* 0.4 134 3.6 103 27 8 +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 94 8 0.5 137 4.1 102 29 10 +[**2131-1-2**] 07:45AM 104 4* 0.5 139 3.8 101 32 10 +[**2131-1-1**] 06:50AM 101 4* 0.6 136 4.2 99 31 10 +[**2130-12-31**] 05:50AM 77 5* 0.5 136 4.31 100 30 10 +[**2130-12-30**] 06:00AM 82 4* 0.6 138 4.1 101 32 9 +[**2130-12-29**] 06:45AM 118* 4* 0.6 136 4.1 99 31 10 +[**2130-12-28**] 05:55AM 83 5* 0.5 137 4.0 100 31 10 +[**2130-12-27**] 10:00AM 49*2 5* 0.5 138 4.1 101 31 10 +SPECIMEN ARRIVED IN LAB AT 12:41PM +[**2130-12-26**] 06:40AM 122* 5* 0.5 134 3.8 100 28 10 +[**2130-12-25**] 06:15AM 78 6 0.5 137 3.9 102 30 9 +[**2130-12-24**] 05:50AM 79 6 0.4 137 4.0 101 30 10 +[**2130-12-22**] 05:35AM 83 6 0.5 138 4.3 102 32 8 +[**2130-12-21**] 06:00AM 78 6 0.5 139 4.0 102 30 11 +[**2130-12-20**] 05:50AM 77 7 0.5 136 3.7 101 30 9 +[**2130-12-19**] 07:00AM 105 7 0.7 139 4.2 101 30 12 +[**2130-12-16**] 09:05AM 106* 8 0.6 137 4.2 100 30 11 +[**2130-12-14**] 07:40AM 96 6 0.5 138 4.3 104 29 9 +[**2130-12-13**] 08:00AM 124* 7 0.5 134 4.2 97 31 10 +[**2130-12-12**] 07:45AM 110* 7 0.5 136 4.0 102 30 8 +[**2130-12-11**] 04:22AM 107* 6 0.5 137 4.0 102 29 10 +[**2130-12-10**] 04:26AM 116* 7 0.6 131* 3.5 98 27 10 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM +[**2130-12-9**] 08:38AM 3.3 +[**2130-12-9**] 04:54AM 97 8 0.6 132* 5.9*3 98 28 12 +GROSS HEMOLYSIS +[**2130-12-8**] 04:25AM 97 13 0.7 135 3.9 99 30 10 +[**2130-12-7**] 03:47AM 142* 15 0.6 133 4.5 97 29 12 +[**2130-12-6**] 03:18AM 138* 10 0.5 136 4.2 98 29 13 +[**2130-12-5**] 10:00AM 115* 10 0.5 132* 4.3 95* 29 12 +[**2130-12-4**] 08:42PM 112* 13 0.5 133 5.04 92* 29 17 +MODERATELY HEMOLYZED SPECIMEN + +HEMOLYSIS FALSELY ELEVATES K +HEMOLYZED, SLIGHTLY +VERIFIED BY REPLICATE ANALYSIS +NOTIFIED T. [**Doctor Last Name **] AT 131PM ON [**2130-12-27**] +HEMOLYSIS FALSELY INCREASES THIS RESULT +HEMOLYSIS FALSELY ELEVATES K. + ESTIMATED GFR (MDRD CALCULATION) estGFR +[**2131-1-12**] 01:00AM Using this1 + +Using this patient's age, gender, and serum creatinine value of +0.5, +Estimated GFR = >75 if non African-American (mL/min/1.73 m2) +Estimated GFR = >75 if African-American (mL/min/1.73 m2) +For comparison, mean GFR for age group 40-49 is 99 (mL/min/1.73 +m2) +GFR<60 = Chronic Kidney Disease, GFR<15 = Kidney Failure + ENZYMES & +B +ILIRUBIN ALT AST LD(LDH) CK(CPK) AlkPhos Amylase TotBili DirBili +[**2131-1-14**] 04:41AM 172* +Source: Line-arterial +[**2131-1-13**] 10:21PM 217* +Source: Line-arterial +[**2131-1-2**] 07:45AM 129 +[**2130-12-5**] 09:10AM 52 +[**2130-12-5**] 01:35AM 48 + CPK ISOENZYMES CK-MB cTropnT +[**2131-1-14**] 04:41AM 2 <0.011 +Source: Line-arterial +[**2131-1-13**] 10:21PM 2 <0.011 +Source: Line-arterial +[**2130-12-5**] 09:10AM 1 <0.011 +[**2130-12-5**] 01:35AM 1 LESS THAN 2 + +<0.01 +CTROPNT > 0.10 NG/ML SUGGESTS ACUTE MI +LESS THAN 0.01 +CTROPNT > 0.10 NG/ML SUGGESTS ACUTE MI + CHEMISTRY TotProt Albumin Globuln Calcium Phos Mg UricAcd Iron +[**2131-1-19**] 12:00AM 3.9 9.0 2.5* 2.1 +Source: Line-PICC +[**2131-1-18**] 12:00AM 9.4 2.5* 2.1 +Source: Line-TLCVL +[**2131-1-17**] 12:00AM 9.1 3.1 2.2 +Source: Line-PICC +[**2131-1-16**] 12:00AM 9.2 2.9 2.1 +Source: Line-PICC +[**2131-1-15**] 02:04AM 8.2* 1.9* 1.8 +Source: Line-arterial +[**2131-1-14**] 04:41AM 8.8 1.3* 1.8 +Source: Line-arterial +[**2131-1-13**] 10:21PM 8.6 1.6* 1.7 +Source: Line-arterial +[**2131-1-13**] 02:24AM 8.3* 2.8 2.1 +Source: Line-aline +[**2131-1-12**] 06:20PM 2.3* 7.8* 3.1 1.2* +Source: Line-arterial ulnar +[**2131-1-12**] 01:00AM 8.7 2.9 2.0 +[**2131-1-2**] 07:45AM 6.0* 9.2 3.8 2.0 +[**2131-1-1**] 06:50AM 9.3 3.7 1.9 +[**2130-12-31**] 05:50AM 8.9 3.5 2.01 +[**2130-12-30**] 06:00AM 9.6 3.5 2.0 +[**2130-12-29**] 06:45AM 8.9 3.4 1.9 +[**2130-12-27**] 10:00AM 9.0 3.3 2.0 +SPECIMEN ARRIVED IN LAB AT 12:41PM +[**2130-12-25**] 06:15AM 9.0 3.2 1.9 +[**2130-12-24**] 05:50AM 1.9 +[**2130-12-21**] 06:00AM 1.9 +[**2130-12-20**] 05:50AM 9.0 3.4 1.9 +[**2130-12-19**] 07:00AM 9.5 3.4 2.0 +[**2130-12-16**] 09:05AM 1.9 +[**2130-12-14**] 07:40AM 8.6 3.3 1.8 +[**2130-12-13**] 08:00AM 8.9 3.1 1.9 +[**2130-12-12**] 07:45AM 8.5 2.3* 1.9 +[**2130-12-11**] 04:22AM 9.0 2.7 1.8 +[**2130-12-10**] 04:26AM 8.9 2.5* 1.8 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM +[**2130-12-9**] 08:38AM 1.8 +[**2130-12-9**] 04:54AM 9.0 3.5 1.81 +GROSS HEMOLYSIS +[**2130-12-8**] 04:25AM 9.1 3.2 1.8 +[**2130-12-7**] 03:47AM 9.8 3.1 2.0 +[**2130-12-6**] 03:18AM 10.0 3.8 1.9 +[**2130-12-5**] 10:00AM 8.5 2.9 1.8 +[**2130-12-4**] 08:42PM 9.2 2.4* 2.02 +MODERATELY HEMOLYZED SPECIMEN + +HEMOLYSIS FALSELY ELEVATES Mg +HEMOLYSIS FALSELY ELEVATES MG. +OTHER CHEMISTRY Osmolal +[**2131-1-13**] 10:21PM 277 +Source: Line-arterial + PITUITARY TSH +[**2130-12-31**] 05:50AM 1.5 +[**2130-12-11**] 04:22AM 0.12* +[**2130-12-10**] 04:26AM 0.29 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM + THYROID T4 T3 calcTBG TUptake T4Index Free T4 +[**2130-12-13**] 08:00AM 12.9* 1.02 0.98 12.6* +[**2130-12-12**] 07:45AM 13.1* 122 1.9* + OTHER ENDOCRINE Cortsol +[**2131-1-13**] 03:34PM 31.3*1 +PLEASE MEASURE THIRTY MINUTES AFTER COSYNTROPIN +[**2131-1-13**] 02:59PM 21.0*1 +[**2130-12-10**] 11:17PM 25.6*1 +[**2130-12-10**] 10:57PM 17.91 +[**2130-12-10**] 10:14PM 4.11 +[**2130-12-10**] 04:26AM 0.9*1 +ADDED TSH [**12-10**] 4:40PM; [**Last Name (un) **] ADDED [**12-10**] 5:05PM + +NORMAL DIURNAL PATTERN: 7-10AM 6.2-19.4 / 4-8PM 2.3-11.9 +GYNECOLOGIC HCG +[**2130-12-4**] 08:42PM <51 +MODERATELY HEMOLYZED SPECIMEN + +<5 +<5 IS NEGATIVE; 5 - 25 IS EQUIVOCAL; >25 IS POSITIVE +LAB USE ONLY RedHold +[**2131-1-6**] 05:40AM HOLD +Blood Gas + BLOOD GASES Type Temp Rates Tidal V PEEP FiO2 O2 +Flow pO2 pCO2 pH calTCO2 Base XS Intubat Comment +[**2131-1-13**] 02:36AM ART 201* 48* 7.40 31* 4 +[**2131-1-12**] 08:41PM ART 35 156* 44 7.42 30 4 NOT +INTUBA1 TRACH MASK +[**2130-12-11**] 08:46PM ART 114* 41 7.46* 30 5 +[**2130-12-8**] 12:33PM ART 159* 38 7.48* 29 5 + +NOT INTUBATED +WHOLE BLOOD, MISCELLANEOUS CHEMISTRY Lactate +[**2131-1-12**] 08:41PM 0.8 +. + +Pathology Examination +Name Birthdate Age Sex Pathology # [**Hospital1 18**] [**Known lastname 71385**],[**Known firstname **] [**Last Name (NamePattern1) 71386**] [**2090-5-18**] 40 Female + [**-7/4872**] [**Numeric Identifier 71387**] +Report to: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) 1533**] +Gross Description by: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **] GOODELL/dif + +SPECIMEN SUBMITTED: Tracheal Tissue. + +Procedure date Tissue received Report Date Diagnosed +by +[**2130-12-8**] [**2130-12-8**] [**2130-12-13**] DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **]/ttl +Previous biopsies: [**-7/2145**] G I BIOPSY (1 JAR). + [**-6/4630**] GASTRIC BX. + [**Numeric Identifier 71388**] RIGHT AND LEFT SEGMENT OF FALLOPIAN TUBES (2). + +DIAGNOSIS: + +Trachea, biopsy: +1. Unremarkable cartilage. +2. Paratracheal soft tissue with acute and chronic +inflammation; no malignancy identified. +. +Pathology Examination +Name Birthdate Age Sex Pathology # [**Hospital1 18**] [**Known lastname 71385**],[**Known firstname **] [**Last Name (NamePattern1) 71386**] [**2090-5-18**] 40 Female + [**Numeric Identifier 71389**] [**Numeric Identifier 71387**] +Report to: DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) 1533**] +Gross Description by: DR. [**Last Name (STitle) **]. [**Doctor Last Name **]/dif + +SPECIMEN SUBMITTED: posterior pleural plaque, inferior pleural +plaque, upper lobe wedge. + +Procedure date Tissue received Report Date Diagnosed +by +[**2131-1-12**] [**2131-1-12**] [**2131-1-16**] DR. [**Last Name (STitle) **] [**Last Name (NamePattern4) **]/dwc?????? +Previous biopsies: [**-7/4872**] Tracheal Tissue. + [**-7/2145**] G I BIOPSY (1 JAR). + [**-6/4630**] GASTRIC BX. + [**Numeric Identifier 71388**] RIGHT AND LEFT SEGMENT OF FALLOPIAN TUBES (2). + +DIAGNOSIS: +Pleura, left posterior plaque, biopsy (A-B): + + Metastatic squamous cell carcinoma. + +Pleura, left inferior plaque, biopsy (C-D): + + Metastatic squamous cell carcinoma. + +Lung, left upper lobe, wedge resection (E-J): + + Metastatic squamous cell carcinoma (see note). + + +Note: +(E-J): Apart from the largest tumor nodule (2 cm in greatest +dimension), multiple small foci of metastatic squamous cell +carcinoma are present along the pleural surface. The surgical +margin of resection appears to be free of tumor. + +Clinical: Esophageal mass, neck pain. +Gross: + +The specimen is received fresh labeled with the patient's name, +""[**Known lastname 19688**], [**Known firstname **] [**Last Name (NamePattern1) **]"", the medical record number and +""pleural plaque."" It consists of a fragment of white - tan firm +tissue measuring 2.5 x 1.5 x 0.6 cm, serially sectioned and +partially frozen. Intraoperative exam was performed. A frozen +section was performed on tissue. The frozen section diagnosis by +Dr. [**Last Name (STitle) **] is ""posterior pleural plaque: metastatic carcinoma."" + + +The remainder of the specimen is entirely submitted in A, frozen +section in B. + +Part 2 is additionally labeled ""inferior pleural plaque."" It +consists of a fragment of firm pink-tan tissue measuring 1.0 x +0.9 x 0.2 cm. The specimen is serially sliced and submitted in +C-D. + +Part 3 is additionally labeled ""left upper lobe wedge RUSH."" It +consists of a wedge resection of lung measuring 6.0 x 3.4 x 1.5 +cm with a stapled margin that measures 8.0 cm in length. The +pleural surface is smooth and shiny, and involved by a white +mass measuring 3.0 x 1.5 cm. This area is firm on palpation. +The specimen is serially sliced to reveal a 2.0 x 2.0 x 1.0 cm +white tan cystic well circumscribed, nodule, located 0.4 cm from +the nearest stapled margin. The mass involves the pleura. The +remainder of the lung parenchyma is unremarkable. The specimen +is represented as follows: E-F = pulmonary resection margin, G-I += tumor in relation to parietal pleura, J = unremarkable lung. +. + + +Brief Hospital Course: +The following summary is divided into sections due to the +patients prolonged hospital course: + +# Esophageal Cancer/Cough/SOB: The patient presented with cough +and SOB. Her symptoms progressed and ENT was consulted. The +patient was found to have superglottic swellling and she was +transferred to the ICU for concern of possible iminent airway +obstruction. A CT of the neck was concerning for perforation +and this finding was reassessed with MRI which raised the +possibility of abcess formation. Given these findings, throacic +surgery was consulted and it was felt that the patient would +benefit from tracheostomy placement for airway protection. A +trach was placed by thoracics on [**2130-12-8**] which was tolerated +well. Speech and swallow followed for assessment for passy muir +valve. + +[**Hospital Unit Name 71390**] COURSE [**12-6**] through [**12-11**] +. +[**12-6**] +- ENT - advised continued MICU care, trachea 3 mm at narrowest +point and supraglottic edema, R vocal cord paralysis +- Thoracics consult- likely not a tear; advised barium swallow +and broad spectrum coverage, ddx perforation vs TE fistula; +- Pt did not tolerate barium swallow +- Added Vanco/Levo/Flagyl/Fluconazole +- MR Neck - read PENDING (wet read by surgery - no ET fistula, +no extaluminal air) +- TFs - restart Ensure +- Evaluated for worsening stridor at 0400; Inspiratory stridor +noted on exam in all lung fields, but pt saturating well. Denies +worsening pain. Thoracics informed. +. +[**Date range (3) 71391**] +- MRI suggestive of micro-esophagael perf, +/- infection +- (Started on Vanco Levo Fluc yesterday [**12-6**]) +- ?Worsening stridor this Morning ([**12-7**]) around 4AM, self +resolved. +- Unless team observes persistent stridor, plan for continuing +Abx, no surgical (trach) intervention at this time. +- had rhoncorous [**Month/Year (2) 1440**] sounds, 3am, cleared on own. +[**12-8**] +- Had trachyostomy; tolerated procedure well. Weaned off vent +overnight and placed on trach mask. +- Per Thoracics, would attempt passy miur valve today. +. +[**12-9**] +- c/od but no bed +- ENT s/o +- CXR shows trach well palced +- tolerated trach proecedure well +- no stridor, no n/v +- restarted tube feeds +- thoracics - 2 wks antibx but will follow on the floor +- patient somewhat confused about cancer dx and prognosis - will +need to have [**Doctor Last Name **]/[**Doctor Last Name **] to explain to patient what to +expect for the future +- continues to be tachycardic +. +12/14-15/08 +-Assessment update: noting low suspicion for esophagael cancer +per Dr. [**Last Name (STitle) 174**]. Concern that chest lesion is met, but not +confirmed. Re: reversibility of trach--if this was esoph perf +[**1-29**] vomiting or [**1-29**] to radiation, likely temporary and may be +removed s/p f/u bronch. +-Refusing depression meds, psychiatry, social work +-Speech and Swallow tomorrow +-Gave 1 L for tachychardia +. +[**2130-12-10**] +Spoke to oncology team re: transfer. Concern that hemodynamics +are slightly worse than on admission. On admission SBPs in 90s, +HR in low 100s, now SBP in 80s, HR 110s. Documented baseline +blood pressures in all discharge summaries from [**2129**] have been +baseline SBPs in the 80s but without tachycardia. Will check +cortisol, TSH. +-Cortisol noted to be quite low. Have ordered supression test. +Will likely need to start treatment steroids s/p test. + +[**2130-12-11**] +-Continuing cough apprecaited. Secretions noted. +-In general, ""still""-appearing, as if in pain, but repeatedly +denies. +- hypotensive to 70's but not symptomatic. Tachy with normal +echo. Good UOP. +Summary of ICU Course: +Briefly, Mrs [**Known lastname 19688**] is a 40 yo F with unresectable esophageal +cancer who was recently discharged from the hospital secondary +to right neck pain. She was then discharged on [**12-1**]. Notes +indicate the patient re-presented on [**12-4**] with the chief +complaint of ""strange sounding airway"" and dyspnea. She was +found to have a soft tissue infection lateral to the esophagus +that likely represents microperforation, for which she was +started on abx, and she required surgical tracheostomy for upper +airway obstruction caused by her esophageal cancer. +. +Additionally, her MICU course was remarkable for persistent +tachycardia and mild hypotension. Her heart rate remains 120s at +rest with brief episodes of rates as high as 150 when she is out +of bed, sinus tachycardia at all times. Her blood pressure has +ranged from 70s-90s systolic, which does not appear to be new, +as OMR notes document systolic blood pressures in the high +80s-low 90s at multiple visits. Evaluation as to the cause of +tachycardia has included TSH (low normal), with fT4 pending; +echo (nml LV and RV function, no echocardiographic signs of +hemodynamically significant PE); ABG 7.46/41/114 was with pt +breathing room air for 10 minutes, indicating that there is no +apparent A-a gradient; a random cortisol level was low, but +responded appropriately to cosyntropin. Since she appears well, +with good skin turgor and adequate urine output, despite the +tachycardia and hypotension, she was transferred out of the ICU. + +The following section summarizes the patients OMED course +including VATS and SICU transfer: +. +40 y/o F with esophageal SCC s/p XRT, s/p tracheostomy for upper +airway compromise with parapharyngeal abscess, now s/p VATs for +LUL cavitary lesion and found to have metastatic esophageal CA. +. +#. Metastatic Esophageal CA: Patient s/p chemo and radiation. +The patient was noted to have a LUL cavitary lesion on CT scan +in early [**Month (only) **]. This was found to have grown by Janurary. +Concern that new lung lesion is secondary to metastatic disease. +A new left sided pleural effusion was seen on CT on [**1-1**]. The +patient underwent thoracentesis on [**1-2**] with 700cc of clear +yellow fluid drained without complication. Cytology and cultures +were sent and the patient was found to have an exudative +effusion. ID was consulted, fungal serologies and stool O&P were +sent. The patient was ruled out for TB on two separate +occasions. Sputum from [**1-5**] grew back Klebsiella Oxytoca, and on +[**1-6**] Acinetobacter both of which were thought to be a +contaminant. The patient was transfered to the [**Hospital Ward Name 516**] on +[**2131-1-12**] to undergo a VATS resection of the the cavitary lesion. +The patient underwent VATS on [**2130-1-11**] which unfortunately +revealed carcinomatous plaques on the pleural wall which were +confirmed frozen section. A chest tube was placed. The patient +briefly required pressers while in the SICU. These were weaned +and the patient was subsequently transfered back to the [**Hospital Ward Name 5074**] on [**1-15**]. Fungal serologies revealed strogyloides and the +patient was given two days of Ivermectin. The patient will +follow-up with Dr. [**Last Name (STitle) **] as an outpatient. +. +#. s/p Trach: The patient was trached on [**12-8**] secondary to +airway compromise. The patient has been breathing comfortably +with trach on 35% trach mask FM; ambulating without supplemental +oxygen; transient dyspnea improves with nebs, anxiolytics. The +patient did not tolerate a PMV on [**1-2**] following completion of a +28 day course of Unasyn and Clindamycin (previously Augmentin). +The patient did not tolerate her PMV mask on [**1-3**]. On [**1-4**] +respiratory therapy attempted to use inhaled fluticasone to +improve her symptoms. The patient was tolerating her PMV +incrementaly more each day. On [**1-7**] the patient was noted to +have increased TM requirements up to 50%. This was thought to be +potentially secondary to reaccumulation of her L pleural +effusion. The patients trach was changed to a 6.0 fenestrated +trach on [**1-16**]. The patient was decannulated by thoracics on [**1-17**] +which she tolerated. Supportive care should be continued upon +discharge. +. +# Healthcare Associated PNA: The patient developed fevers and +had continued cough following her VATS. The patient was placed +empirically on Cefepime on [**1-15**], this was later changed to +Levaquin upon discharge for a planned 10 day total duration of +antibiotics. Cultures were NGTD at the time of discharge. +. +# Parapharygneal Abscess. The patient was placed initially on +Augmentin. This was changed to Unasyn / Clindamycin for which +she subsequently completed 28 days of treatement. ENT evaluated +patient [**1-1**] no upper airway abnormality other than copious +secretions. A CT Neck and Chest on [**1-2**] revealed both +tetropharyngeal and retrotracheal swelling as well as soft +tissue density encompassing the esophagus. This was thought to +potentially represent post-radiation changes and phlegmon. No +evidence of a drainable fluid collection. +. +#. Neutropenia: Initially thought to be secondary to patients +being on augmentin. This was subsequently changed to +Clindamycin/Unasyn or compazine. ANC subsequenrly resolved to +1278 [**1-1**]. +. +#. Anemia: Currently at baseline, no signs of active bleeding. +Con't to monitor. There was question of benefit of higher +transfusion threshold to reduce tachycardia. +. +#. Tachycardia: The patient has been persistently in sinus +tachycardia 110-130 bpm. The patient was evaluate while in the +ICU that indicated a low probibility for PE, no signs of CHF, +and potentially subclinical hyperthyroidism although TSH WNL. +There was thought that part of the ST was secondary to anxiety. +Anemia also potentially played a role. +- Cont Tele +. +#. Hypotension: Asymptomatic and maintaining MAP >= 60. Responds +well to fluid bolus when systolics drift down to 70s. Continue +vol challenge prn. Was briefly on pressers while in the unit, +now weaned off. +. +#. Pain: The patients pain was well-controlled with gabapentin +and methadone. The patient was written for Morphine PRN. +. +# Depression: The patient remains on nortriptyline for depressed +mood and will not take additional treatment. Likely that some of +this is related to coping with general medical illness as well +as underlying depression and being away from her children. +- SW will cont to follow +- cont nortriptyline +. +#. Steroid-Induced DM: continue SSI; if requirements trend down +now that off steroids, can D/C insulin + +Medications on Admission: +Tylenol occasionaly +Lactulose 30 cc tid prn +Methadone 2.5 mg [**Hospital1 **] +. +Upon transfer out of the MICU: +. +Heparin 5000 UNIT SC TID +Insulin SC +Lactulose 30 mL PO Q8H:PRN Order date: [**12-12**] @ 0050 +Levofloxacin 750 mg IV Q24H day 1 = [**12-6**] +Methadone 2.5 mg PO BID +Acetaminophen (Liquid) 325-650 mg PO Q6H:PRN +MetRONIDAZOLE (FLagyl) 500 mg IV Q8H day 1 = [**12-6**] +Albuterol 0.083% Neb Soln 1 NEB IH Q6H:PRN +Nortriptyline 25 mg NG HS +Ondansetron 8 mg IV Q 8H +Pantoprazole 40 mg IV Q12H +Docusate Sodium (Liquid) 100 mg PO BID PRN +Prochlorperazine 25 mg PR Q12H +Fluconazole 200 mg NG Q24H day 1 = [**12-6**] +Gabapentin 300 mg PO QAM & 600 mg PO QPM +Vancomycin 1000 mg IV Q 12H day 1 = [**12-6**] + + +Discharge Medications: +1. Nortriptyline 10 mg/5 mL Solution [**Month/Year (2) **]: One (1) PO HS (at +bedtime). +2. Methadone 5 mg Tablet [**Month/Year (2) **]: 0.5 Tablet PO BID (2 times a day). + +3. Lactulose 10 gram/15 mL Syrup [**Month/Year (2) **]: Thirty (30) ML PO Q8H +(every 8 hours) as needed for constipation. +Disp:*300 ML(s)* Refills:*2* +4. Senna 8.8 mg/5 mL Syrup [**Month/Year (2) **]: Five (5) ML PO BID (2 times a +day). +Disp:*300 ML(s)* Refills:*2* +5. Acetaminophen 160 mg/5 mL Solution [**Month/Year (2) **]: [**12-29**] tsp PO Q6H (every +6 hours) as needed for fever or pain. +Disp:*1 Bottle* Refills:*2* +6. Guaifenesin 100 mg/5 mL Syrup [**Month/Day (2) **]: Fifteen (15) ML PO Q6H +(every 6 hours) as needed for cough. +Disp:*200 ML(s)* Refills:*1* +7. Lansoprazole 30 mg Tablet,Rapid Dissolve, DR [**Last Name (STitle) **]: One (1) +Tablet,Rapid Dissolve, DR [**Last Name (STitle) **] DAILY (Daily). +Disp:*30 Tablet,Rapid Dissolve, DR(s)* Refills:*2* +8. Docusate Sodium 50 mg/5 mL Liquid [**Last Name (STitle) **]: Ten (10) mL PO BID (2 +times a day). +Disp:*600 mL* Refills:*2* +9. Bisacodyl 10 mg Suppository [**Last Name (STitle) **]: One (1) Suppository Rectal +[**Hospital1 **] (2 times a day) as needed for constipation. +10. Compazine 5 mg Tablet [**Hospital1 **]: 1-2 Tablets PO every 4-6 hours as +needed for nausea: crush & mix with water. . +Disp:*30 Tablet(s)* Refills:*0* +11. Ativan 1 mg Tablet [**Hospital1 **]: [**12-29**] - 1 Tablet PO every 4-6 hours as +needed for anxiety. +Disp:*30 Tablet(s)* Refills:*0* +12. Levofloxacin 500 mg Tablet [**Month/Day (2) **]: One (1) Tablet PO once a day +for 5 days. +Disp:*5 Tablet(s)* Refills:*0* + + +Discharge Disposition: +Home With Service + +Facility: +[**Hospital **] hospice care + +Discharge Diagnosis: +Primary Diagnosis +- Metastatic Esophageal CA +- Parapharyngeal Abcess +- Left Pleural Effusison +- Health-Care Acquired PNA + + +Discharge Condition: +good. Patient abulating. PEG in place. Tolerating +De-Cannulation. + + +Discharge Instructions: +You were admitted to hospital with shortness of [**Hospital 1440**] and +wheezing. You were found to have an infection in your throat for +which you received antibiotics. A breathing tracheostomy was +placed so that you were able to [**Hospital 1440**]. This infection was +treated and you are now able to breathe without the tube. The +hole in your neck should close up on its own, you do not need to +do anything about this. + +You were found to have a growning lesion in your left lung and +you underwent an operation to removed the lesion as well as +fluid. You were found to have recurrence of your esophageal +cancer. Dr. [**Last Name (STitle) **] will see you in clinic to discuss chemotherapy. + +You were also treated for a pneumonia. You need to take 5 more +days of an antibiotic called levofloxacin. + +Please continue to take all of your medications as listed below. +A number of changes have been made. + +Please keep all of your appointments. + +Please call your doctor if you experience continued fevers, +chills, shortness of [**Last Name (STitle) 1440**], chest pain, nausea, vomitting, +diarrhea. + +Followup Instructions: +With Dr. [**Last Name (STitle) 71392**] on [**1-30**] at 1:30 PM on [**Hospital Ward Name 23**] 9. + +Provider: [**First Name4 (NamePattern1) 1386**] [**Last Name (NamePattern1) **], MD Phone:[**Telephone/Fax (1) 463**] +Date/Time:[**2131-1-25**] 12:45 +Provider: [**Name10 (NameIs) 4617**] [**Name8 (MD) **], [**MD Number(3) 1240**]:[**Telephone/Fax (1) 7976**] Date/Time:[**2131-1-26**] +2:15 +Provider: [**Name10 (NameIs) **] [**Last Name (NamePattern4) 8268**], MD Phone:[**Telephone/Fax (1) 7976**] Date/Time:[**2131-1-29**] +10:30 + +Provider: [**Name10 (NameIs) **] [**Name8 (MD) 490**], MD, PHD[**MD Number(3) 708**]:[**0-0-**] +Date/Time:[**2131-2-8**] 9:00 + + + +",143,2130-12-04 19:01:00,2131-01-19 21:25:00,EMERGENCY,PHYS REFERRAL/NORMAL DELI,HOME HEALTH CARE,"ESOPHAGEAL MASS, NECK PAIN"," +the following summary is divided into sections due to the + ","PRIMARY: [Malignant neoplasm of cervical esophagus] +SECONDARY: [Perforation of esophagus; Secondary malignant neoplasm of lung; Malignant pleural effusion; Parapharyngeal abscess; Pneumonia, organism unspecified; Stricture and stenosis of esophagus; Unspecified disease of the jaws; Radiological procedure and radiotherapy as the cause of abnormal reaction of patient, or of later complication, without mention of misadventure at time of procedure; Accidents occurring in other specified places; Anemia in neoplastic disease; Stenosis of larynx; Drug induced neutropenia; Penicillins causing adverse effects in therapeutic use; Accidents occurring in residential institution]" +86146,128337.0,8936,2104-02-19,8935,112417.0,2103-12-21,Discharge summary,"Admission Date: [**2103-12-16**] Discharge Date: [**2103-12-21**] + +Date of Birth: [**2047-1-31**] Sex: M + +Service: MEDICINE + +Allergies: +Penicillins + +Attending:[**First Name3 (LF) 2641**] +Chief Complaint: +seizures + +Major Surgical or Invasive Procedure: +none + +History of Present Illness: +56 yo M with PMH of alcohol abuse and alcohol withdrawal +seizures who presents s/p seizures at home. Patient is Spanish +speaking only so most of history obtained from his wife and some +from patient as well. +. +Patient says he drinks vodka but says he last drink was Monday +(6 days prior to presentation). His wife confirms she believes +this is true. She reports that she came home from work yesterday +and the patient had a black eye on the right which he told her +was from a fall. He also may have vomited yesterday although +this history is not clear. Then today she and her daughter +witnessed him seizing. Whole body shaking with all limbs moving. +No loss of bowel or bladder continence. Lasted about one min +then stopped. Then started again for another min. She reports he +was confused and did not know who she was afterwards. She called +EMS to bring him to the ED. She reports he had this about 6 +months ago and was told it was from alcohol use. She also +reports that he has not been eating well secondary to his +esophageal stricture which was recently dilated by GI here. +. +In the ED, his initial vital signs were T 98.7, BP 131/80, HR +86, RR 18, O2sat 100% RA. He was given potassium, magnesium, +banana bag and ativan per CIWA scale (about 6-8mg total). +Neurology was consulted in the ED as well. He had a trauma work +up for CT c-spine, head and maxillary/mandible all of which were +negative for fracture. CXR was unchanged with no acute process. +He was sent to the ICU for further care. + + +Past Medical History: +-ETOH abuse c/b withdrawal seizures +-Chronic liver disease c/b pancytopenia-f/up unclear +-esophageal stricture recently dilated by Dr. [**Last Name (STitle) 174**] +[**Name (STitle) 31040**] c/b pneumothoraces in [**2094**]. He completed antibiotic regimen +per notes. + +Social History: +The patient immigrated from [**Country 7192**] in [**2078**]. Married with +daughters. Smokes cigars. Drinks at vodka per him and his wife, +at least a pint a day. Prior notes comment on rum as well. + +Family History: +unknown + +Physical Exam: +General: thin, malnurished male in NAD, but tremulous. Not +diaphoretic. +HEENT: Has hematoma and ecchymosis over right eye which is shut. +PERRL, anicteric sclera. non-injected conjunctiva. OP clear but +dry MM +CV: RRR soft 1/6 SEM but distant heart sounds +Lungs: CTAB no w/r/r +Abdomen: +BS, soft, NTND +Ext: no e/c/c +Neuro: difficult to assess given language difficulty. Strength +seems full throughout. no neck tenderness with FROM. +asterixis. +Toes mute. Reflexes in tact. + +Pertinent Results: +[**2103-12-16**] 10:09AM BLOOD WBC-6.9 RBC-3.71* Hgb-12.7* Hct-36.2* +MCV-97 MCH-34.1* MCHC-35.0 RDW-12.7 Plt Ct-114* +[**2103-12-16**] 10:09AM BLOOD Neuts-70.8* Lymphs-22.9 Monos-5.6 Eos-0.2 +Baso-0.5 +[**2103-12-18**] 03:21AM BLOOD PT-13.4 PTT-48.8* INR(PT)-1.2* +[**2103-12-16**] 10:09AM BLOOD Glucose-169* UreaN-9 Creat-0.6 Na-137 +K-2.7* Cl-89* HCO3-35* AnGap-16 +[**2103-12-16**] 10:09AM BLOOD ALT-21 AST-70* LD(LDH)-329* CK(CPK)-219* +AlkPhos-124* TotBili-2.2* +[**2103-12-16**] 10:09AM BLOOD ASA-NEG Ethanol-NEG Acetmnp-NEG +Bnzodzp-NEG Barbitr-NEG Tricycl-NEG +. +Head CT [**2103-12-16**]: The study is limited due to motion artifact. +There is no intracranial mass lesion, hydrocephalus, shift of +normally midline structures, major vascular territorial infarct, +or intracranial hemorrhage. The [**Doctor Last Name 352**]-white matter +differentiation is preserved. The study is limited due to motion +artifact for the evaluation of the orbits; however, no displaced +fracture is identified. There is a large right periorbital +hematoma. The ocular globes appear intact. +. +CT Mandible, Sinus [**2103-12-16**]: The cribriform plate appears +intact. The nasal septum is mildly deviated to the right. There +is a small air-fluid level in the right maxillary sinus. No +acute fracture is identified. Right periorbital soft tissue +hematoma is seen. +. +CT C-Spine [**2103-12-16**]: There is no prevertebral soft tissue +swelling. The +alignment is maintained without spondylolisthesis. No acute +fracture is +identified. The odontoid process is intact. Multilevel +degenerative changes, worse at the level of C5-6 and C6-7. The +visualized lung apices demonstrate a left apical bleb. Bilateral +apical pleural thickening. The visualized paranasal sinuses +demonstrate minimal opacification of the right maxillary sinus. +Soft tissue density in both external auditory canals may +represent cerumen. Clinical correlation is recommended. +. +Chest X-ray [**2103-12-16**]: 1. Small nodular opacities within the left +mid lung field, which were present on the previous chest CT, may +be slightly improved. Findings may represent small airways +infection or aspiration. +2. Post-surgical changes, right lung. +. +Barium Swallow [**2103-12-21**] (preliminary read): No esophageal +diverticulum seen. Narrowing of distal esophagus with holdup of +13 mm barium tablet, without holdup of barium. No dysmotility or +reflux seen. +. +Pending studies at the time of discharge: +Final read of Barium swallow study + +Brief Hospital Course: +1. SEIZURES +Mr. [**Known lastname **] was admitted to the MICU after having 2 witnessed +seizures in the setting of alcohol withdrawal. He said that it +had been 6 days since his last drink and had a history of +seizures 6 months prior in the setting of alcohol withdrawal. +His ETOH level was negative on tox screen. Neurology was +consulted in the ED and recommended and outpatient EEG. He was +put on a CIWA protocol and given Diazepam PO to treat his +withdrawal. He required IV Ativan initially to control his +symptoms but then was given PO Diazepam. His withdrawal +sytmptoms were controlled and he had no witness seizures during +this hospital stay. He was given thiamine, folate and a +multivitamin and was put on a PPI. He was transferred to the +medicine floor on [**2103-12-19**]. He continued to have no seizures +for the remainder of his hospital course. He was scheduled for +outpatient neurology follow-up and will be called by the EEG lab +regarding scheduling of an outpatient EEG. +. +2. ALCOHOL ABUSE +Mr. [**Known lastname **] was given IV Ativan initially for withdrawal and this +was later changed to PO Diazepam. He required no further +benzodiazepines after [**2103-12-19**]. He was seen by the addiction +social worker who suggested inpatient rehab program but he +preferred to seek help at outpatient treatment centers and was +given a list of programs prior to discharge. He was advised not +to drink alcohol. His liver function tests were normal through +his hospital course. +. +3. DYSPHAGIA +Mr. [**Known lastname **] had a history of dysphagia and prior EGDs with +dilation. Several prior biopsies had shown no evidence of +cancer. On admission he stated that he had dysphagia to thick +meats such as steak. He was evaluated by a barium swallow study +which showed hold-up of a 13mm barium tablet but no hold-up of +the liquid barium and no diverticulum. His outpatient +gastroenterologist, Dr. [**Last Name (STitle) 174**] was contact[**Name (NI) **] and suggested +outpatient follow-up for this problem with another EGD and +possibe sugerical referral in the future. Mr. [**Known lastname **] was given +an appointment to see Dr. [**Last Name (STitle) 174**] in [**Month (only) 404**]. He was evaluated by +speech and swallow who stated that he had no difficulty in +swallowing above the epiglottis. He was advised not to eat +steak and to seek medical attension if he had pain with +swallowing or the feeling of food getting stuck in his throat. +He was advised to seek medical attention if he could not +maintain his weight properly with foods. +. +4. PROPHYLAXIS +Mr. [**Known lastname **] was put on SC heparin for DVT prophylaxis, a PPI and a +bowel regimen during his hospital course. He was given a +prescription for a PPI as an outpatient. +. +Prior to discharge, Mr. [**Known lastname **] was evaluated by PT who +recommended outpatient PT for [**2-25**] more days and ambulation with +a cane, as the patient was not entirely steady on his feet. + +Medications on Admission: +none + +Discharge Medications: +1. Thiamine HCl 100 mg Tablet Sig: One (1) Tablet PO DAILY +(Daily). +2. Folic Acid 1 mg Tablet Sig: One (1) Tablet PO DAILY (Daily). + +3. Multivitamin Tablet Sig: One (1) Tablet PO DAILY (Daily). + +4. Pantoprazole 40 mg Tablet, Delayed Release (E.C.) Sig: One +(1) Tablet, Delayed Release (E.C.) PO Q24H (every 24 hours). +Disp:*30 Tablet, Delayed Release (E.C.)(s)* Refills:*0* +5. Outpatient Physical Therapy +Diagnosis: Alcohol Withdrawal, ambulate with LRAD, 1-2 visits + + +Discharge Disposition: +Home + +Discharge Diagnosis: +Primary Diagnosis: +1. Alcohol Withdrawal Seizures +. +Secondary Diagnoses: +2. Dysphagia +3. Alcohol Abuse +4. Fatty Liver Disease + + +Discharge Condition: +afebrile, hemodynamically stable + + +Discharge Instructions: +You were admitted to the hospital with seizures in the setting +of alcohol withdrawal. You were given benzodiazepines to treat +your withdrawal symptoms. Your symptoms improved and you did +not require benzodiazepines any longer prior to discharge. You +were evaluated by neurology for your seizures who felt that they +were due to alcohol withdrawal and you should have outpatient +follow-up. You had an x-ray to evaluate your esophagus during +this admission. +. +You were started on a multivitamin, thiamine and folate during +this admission. You should continue to take these at home and +can buy them over-the-counter. You should take also take a +proton-pump inhibitor. +. +You had an esophageal barium swallow study to evaluate your +dysphagia. You should follow-up with Dr. [**Last Name (STitle) 174**] for this as +described below. +. +You should follow-up with Neurology with an EEG and appointment +with Dr. [**Last Name (STitle) 2340**] as described below. The EEG will be scheduled +by Neurology and they will contact you on monday to schedule +this. You should follow-up with your primary care physician, +[**Last Name (NamePattern4) **]. [**Last Name (STitle) **] regarding treatment for your alcoholism and further +care. You were provided with phone numbers for outpatient +substance abuse treatment centers on discharge. +. +You should call your doctor or come to the emergency room for +any fevers > 100.4, chills, night sweats, seizures, weakness or +numbness in any parts of your body, severe headache, vision +changes, vomiting, abdominal pain or any other symptoms that +concern you. Please call Dr.[**Name (NI) 31041**] office if you have any +difficulty swallowing or feeling of food getting stuck in your +throat. + +Followup Instructions: +Provider: [**Name10 (NameIs) 1382**] [**Name11 (NameIs) 1383**], MD Phone:[**Telephone/Fax (1) 2422**] +Date/Time:[**2103-12-31**] 10:30 +Provider: [**Name10 (NameIs) **] [**Last Name (STitle) **] & DR [**Last Name (STitle) 8618**] Phone:[**Telephone/Fax (1) 44**] +Date/Time:[**2104-1-16**] 2:00 +. +Provider: [**Last Name (NamePattern4) **]. [**Last Name (STitle) 174**] (Gastroenterology) [**2103-1-27**] at 1:45pm. Rhabb +building [**Location (un) 453**]. [**Telephone/Fax (1) 463**] + + + +",60,2103-12-16 17:51:00,2103-12-21 20:28:00,EMERGENCY,EMERGENCY ROOM ADMIT,HOME,ETOH WITHDRAWAL," +1. seizures +mr. [**known lastname **] was admitted to the micu after having 2 witnessed +seizures in the setting of alcohol withdrawal. he said that it +had been 6 days since his last drink and had a history of +seizures 6 months prior in the setting of alcohol withdrawal. +his etoh level was negative on tox screen. neurology was +consulted in the ed and recommended and outpatient eeg. he was +put on a ciwa protocol and given diazepam po to treat his +withdrawal. he required iv ativan initially to control his +symptoms but then was given po diazepam. his withdrawal +sytmptoms were controlled and he had no witness seizures during +this hospital stay. he was given thiamine, folate and a +multivitamin and was put on a ppi. he was transferred to the +medicine floor on [**2103-12-19**]. he continued to have no seizures +for the remainder of his hospital course. he was scheduled for +outpatient neurology follow-up and will be called by the eeg lab +regarding scheduling of an outpatient eeg. +. +2. alcohol abuse +mr. [**known lastname **] was given iv ativan initially for withdrawal and this +was later changed to po diazepam. he required no further +benzodiazepines after [**2103-12-19**]. he was seen by the addiction +social worker who suggested inpatient rehab program but he +preferred to seek help at outpatient treatment centers and was +given a list of programs prior to discharge. he was advised not +to drink alcohol. his liver function tests were normal through +his hospital course. +. +3. dysphagia +mr. [**known lastname **] had a history of dysphagia and prior egds with +dilation. several prior biopsies had shown no evidence of +cancer. on admission he stated that he had dysphagia to thick +meats such as steak. he was evaluated by a barium swallow study +which showed hold-up of a 13mm barium tablet but no hold-up of +the liquid barium and no diverticulum. his outpatient +gastroenterologist, dr. [**last name (stitle) 174**] was contact[**name (ni) **] and suggested +outpatient follow-up for this problem with another egd and +possibe sugerical referral in the future. mr. [**known lastname **] was given +an appointment to see dr. [**last name (stitle) 174**] in [**month (only) 404**]. he was evaluated by +speech and swallow who stated that he had no difficulty in +swallowing above the epiglottis. he was advised not to eat +steak and to seek medical attension if he had pain with +swallowing or the feeling of food getting stuck in his throat. +he was advised to seek medical attention if he could not +maintain his weight properly with foods. +. +4. prophylaxis +mr. [**known lastname **] was put on sc heparin for dvt prophylaxis, a ppi and a +bowel regimen during his hospital course. he was given a +prescription for a ppi as an outpatient. +. +prior to discharge, mr. [**known lastname **] was evaluated by pt who +recommended outpatient pt for [**2-25**] more days and ambulation with +a cane, as the patient was not entirely steady on his feet. + + ","PRIMARY: [Alcohol withdrawal] +SECONDARY: [Unspecified protein-calorie malnutrition; Other convulsions; Alcoholic fatty liver; Other and unspecified alcohol dependence, unspecified; Thrombocytopenia, unspecified; Black eye, not otherwise specified; Unspecified fall; Conjunctivitis, unspecified; Stricture and stenosis of esophagus; Personal history of tuberculosis]" +93632,159011.0,15560,2108-01-30,15559,199940.0,2108-01-19,Discharge summary,"Admission Date: [**2108-1-4**] Discharge Date: [**2108-1-19**] + +Date of Birth: [**2026-2-17**] Sex: M + +Service: SURGERY + +Allergies: +Patient recorded as having No Known Allergies to Drugs + +Attending:[**First Name3 (LF) 4748**] +Chief Complaint: +bilateral gangrenous wounds of lower extremity + +Major Surgical or Invasive Procedure: +[**2108-1-5**] Left fem-post tib in-situ Non-reversed saphenous veni +graft + + +History of Present Illness: +81y/o male s/p rt. athectomy of SFa and PFS with left EIA +stenting [**9-20**] hospitalized [**2107-12-26**] for cellulitis anf gangrene +of left heel and +ulcer with ganganerous changes of rty. calf wound . under went +diagnositic angiogram which demonstrated left SFA occlusion with +90% stenosis of mid PFA and single vessel via AT with occlusion +of at at ankle and foot perfused by colateral circulation. +Returns now for elective left fem-at bpg and perioperative +antibiotics. patient was on levofloxcin without improvement of +wound. Ambulates around room with walker. ABI rt. 0.68 ABI left +0.57 + + +Past Medical History: +PVD w/ bilateral gangrenous wounds of lower extremity +history of Hypertension +history of Gout +history of BPH + +PSH: s/p rt. sfa/paf ahtrectomy with Lt. EIA stent [**9-20**],angio +[**2107-12-26**] occluded left SFA single vessel runoff AT which occludes +at ankle, foot perfused by collaterals. +s/p TURP +S/p hernia repairs +s/p Appendectomy +S/P right lower extremity DVT in [**2081**] + +Social History: +Social history resident since d/c [**12-23**] A nursing home in +[**Location (un) 620**], +ma, retired, nonsmoker or drinker. + +Daughter involved in her care: phone [**Telephone/Fax (1) 45026**] + + +Family History: +n/c + +Physical Exam: +Gen: NAD +Card: RRR +Lungs: CTAB +Abd: good bowel sounds, soft, non-tender, non-distended +Extrem: well perfused +pulses: fem [**Doctor Last Name **] dp pt +left palp dop dop dop +Right palp palp palp dop + + +Pertinent Results: +[**2108-1-6**] 03:59AM BLOOD WBC-13.4* Hgb-10.5* Hct-28.9* Plt Ct-265 +[**2108-1-5**] 05:02PM BLOOD Hgb-11.8* Hct-33.5* Plt Ct-344 +[**2108-1-6**] 03:59AM BLOOD Plt Ct-265 +[**2108-1-5**] 05:02PM BLOOD Plt Ct-344 +[**2108-1-6**] 03:59AM BLOOD Glucose-92 UreaN-37* Creat-0.7 Na-144 +K-3.6 Cl-116* HCO3-23 AnGap-9 +[**2108-1-6**] 12:59AM BLOOD K-3.9 +[**2108-1-5**] 05:02PM BLOOD Glucose-122* UreaN-39* Creat-0.7 Na-143 +K-3.2* Cl-111* HCO3-24 AnGap-11 + +ECG Study Date of [**2108-1-4**] 12:53:52 PM +Normal sinus rhythm, rate 79. Occasional atrial premature beats. + + + +CHEST (PRE-OP PA & LAT) Study Date of [**2108-1-4**] 5:23 PM +AP UPRIGHT AND LATERAL CHEST: The cardiomediastinal silhouette +is normal. Ill definied opacity in the right lower lobe is +concerning for pneumonia. The left lung is grossly unremarkable. +There is no evidence of effusion or +pneumothorax. Moderate multilevel degenerative changes in the +thoracolumbar spine are similar to [**2101-8-30**]. +IMPRESSION: Findings are concerning for right lower lobe +pneumonia. + +TEE (Complete) Done [**2108-1-5**] at 3:51:36 PM +No spontaneous echo contrast or thrombus is seen in the body of +the left atrium/left atrial appendage or the body of the right +atrium/right atrial appendage. No atrial septal defect is seen +by 2D or color Doppler. Left ventricular wall thicknesses and +cavity size are normal. Although not seen, due to suboptimal +technical quality, a focal wall motion abnormality cannot be +fully excluded. Overall left ventricular systolic function is +low normal (LVEF 50%). Right ventricular chamber size and free +wall motion are normal. There are complex (>4mm) atheroma in the +aortic arch. There are simple atheroma in the descending +thoracic aorta. The aortic valve leaflets (3) are mildly +thickened but aortic stenosis is not present. Trace aortic +regurgitation is seen. The mitral valve leaflets are mildly +thickened. Physiologic mitral regurgitation is seen (within +normal limits). Drs. [**Last Name (STitle) 45027**] and [**Name5 (PTitle) 1391**] were notified in +person of the results in the opertaing room at the time of the +study. + +ECG Study Date of [**2108-1-5**] 11:05:30 AM +Normal sinus rhythm, rate 86, with frequent atrial premature +beats and +brief multifocal atrial tachycardia. + + + +Brief Hospital Course: +[**2108-1-4**] Patient admitted. Routine nursing care, labs, ECG, CXR +were done. CXR-showed LLL pneumonia. DVT prophylaxis started. +Pre-angio and consented for [**2108-1-5**]. Initial Trop .06, continued +to monitor cardiac enzymes. + +[**2108-1-5**] Underwent successful left femoral-posterior tibial +bypass. Central line/PA line, foley, and A-line were plaved. +Recovered in the PACU, then transferred to [**Hospital Ward Name 121**] 5 VICU, +continued w/ telemetry. Cardiology consulted for elevated +Troponin- recs- maximize beta blocker and monitor cardiac +enzymes. +[**2108-1-6**] POD1 on lower extremity bypass pathway. Speech and +swallow consult for ? aspiration pneumonia, unable to do video +swallow- to be done on Monday [**1-9**], kept NPO. +1/24-25/09 POD2-3 No acute events, continue to be NPO. Started +TPN. Transfused 1 unit PRBCs Hct 25.9<-33.9 on admission. +Electrolytes repleted. +[**2108-1-9**] POD4 speech and swallow re-evaluation at bedside, +continue to have possible aspirations-recs continue to keep NPO, +TPN for nutrition. Scheduled for video swallow on [**1-12**]. +[**2108-1-10**] POD#5 Continues to be NPO, on TPN. No acute events. +Taken to OR for wound revision of dehised L LE surgical wound. +[**2108-1-11**] POD#6 somulent, breath sound with ronchi. Intubated and +transfered to CTICU for pulmonary acre. Daugnter pat notifed of +event.Bronchoscoopy done. findings no airway mucus or +secreations , new LLL pneumonia. BAL sent.Gen surgery consulted +for PEG placement.Zosyn added to Vanco for his hospital +acquired pneumonia. +[**2108-1-12**] POD#7 Video swalow cancelled patient still intubated.PEG +placement. remains NPO and on TPN. Iv antibiotics continued. +Speech and swallow signed off.low urinary out put-fluid +resustated.Extubated.Transfered to VICU for continued care. +[**2108-1-13**] POD#[**7-14**] no overnight events. afebrile. TPN continued. +Gen. surgery- recs not to use PEG till POD 2. Noted to have +large decubiti in his scarl area, wound care nurse consulted, +placed in air mattress. Changed to floor status. +[**2108-1-14**] POD9/2 no acute events. Started slow tube feeds via +gastric tube. Continues w/ TPN via central line. Continues on +antibiotics Vanco/Zosyn. +[**2108-1-15**] POD10/3 No acute events. Continue tube feeds-advances to +goal (60cc/h), TPN. Continues on antibiotics Vanco/Zosyn. +Physical therapy consult. Rehab screening. +[**Date range (1) 45028**] POD11-12/4-5 No acute events, tube feeds at goal, TPN +d/c'd. Continues on Vanco/Zosyn. [**Hospital 25403**] rehab bed. L leg +distal wound still draining, aced from forefoot-below knee. +[**2108-1-18**] POD12/6 No acute events. Continues on Vanco/Zosyn. +Physical therapy following. [**Hospital 25403**] rehab bed. +[**2108-1-19**] POD13/6 D/C to rehab with one week of PO bactrim. + + +Medications on Admission: +asa 325mg po qd +plavix 75 m qd +altace 2.5 mg qd +multivitamin +ariecept 10 mg po qd +zocor 40 mg po qd +lopressor 12.5 mg po qd +prilosec 20 mg po qd +levoflox 500 mg po qd + +Discharge Disposition: +Extended Care + +Facility: +[**Location (un) 1036**] - [**Location (un) 620**] + +Discharge Diagnosis: +PVD w/ bilateral gangrenous wounds of lower extremity +Pre-admission Pneumonia-likely due to aspiration +Sacral decubiti- stage III, sacral- wound care consulted-placed +on air mattress +Dysphagia +history of Hypertension +history of Gout +history of BPH +postoperative hypoxia [**1-16**] to progressive unilateral to bilateral +pneumonia requiring intubation +postopaerative faiure to thrive [**1-16**] Pna, tpn +postoperative acute blood loss anemia, transfused. + +PSH: s/p rt. sfa/paf ahtrectomy with Lt. EIA stent [**9-20**],angio +[**2107-12-26**] occluded left SFA single vessel runoff AT which occludes +at ankle, foot perfused by collaterals. +S/p hernia repairs +s/p Appendectomy +S/P right lower extremity DVT in [**2081**] + + +Discharge Condition: +Stable + + +Discharge Instructions: +LE Bypass +- ambulate essential distances untill FU with Dr. [**Last Name (STitle) 1391**] +- Ace wrap leg from foot-knee when ambulating +- Elevate leg when sitting +- no driving till FU +- may shower, no tub baths +- Keep wound dry and clean, call if noted to have redness, +draining, swelling, or if temp is greater than 101.5 +- Continue all medications as directed +- Keep all FU appointments +- Call Dr.[**Name (NI) 1392**] office for FU appointment + + +Followup Instructions: +Call for 2 weeks Follow-up w/ Dr. [**Last Name (STitle) 1391**] Phone: [**Telephone/Fax (1) 1393**] + + + +Completed by:[**2108-1-19**]",11,2108-01-04 14:00:00,2108-01-19 16:32:00,ELECTIVE,PHYS REFERRAL/NORMAL DELI,SNF,NONHEALING ULCER LEFT LOWER EXTREMITY," +[**2108-1-4**] patient admitted. routine nursing care, labs, ecg, cxr +were done. cxr-showed lll pneumonia. dvt prophylaxis started. +pre-angio and consented for [**2108-1-5**]. initial trop .06, continued +to monitor cardiac enzymes. + +[**2108-1-5**] underwent successful left femoral-posterior tibial +bypass. central line/pa line, foley, and a-line were plaved. +recovered in the pacu, then transferred to [**hospital ward name 121**] 5 vicu, +continued w/ telemetry. cardiology consulted for elevated +troponin- recs- maximize beta blocker and monitor cardiac +enzymes. +[**2108-1-6**] pod1 on lower extremity bypass pathway. speech and +swallow consult for ? aspiration pneumonia, unable to do video +swallow- to be done on monday [**1-9**], kept npo. +1/24-25/09 pod2-3 no acute events, continue to be npo. started +tpn. transfused 1 unit prbcs hct 25.9<-33.9 on admission. +electrolytes repleted. +[**2108-1-9**] pod4 speech and swallow re-evaluation at bedside, +continue to have possible aspirations-recs continue to keep npo, +tpn for nutrition. scheduled for video swallow on [**1-12**]. +[**2108-1-10**] pod#5 continues to be npo, on tpn. no acute events. +taken to or for wound revision of dehised l le surgical wound. +[**2108-1-11**] pod#6 somulent, breath sound with ronchi. intubated and +transfered to cticu for pulmonary acre. daugnter pat notifed of +event.bronchoscoopy done. findings no airway mucus or +secreations , new lll pneumonia. bal sent.gen surgery consulted +for peg placement.zosyn added to vanco for his hospital +acquired pneumonia. +[**2108-1-12**] pod#7 video swalow cancelled patient still intubated.peg +placement. remains npo and on tpn. iv antibiotics continued. +speech and swallow signed off.low urinary out put-fluid +resustated.extubated.transfered to vicu for continued care. +[**2108-1-13**] pod#[**7-14**] no overnight events. afebrile. tpn continued. +gen. surgery- recs not to use peg till pod 2. noted to have +large decubiti in his scarl area, wound care nurse consulted, +placed in air mattress. changed to floor status. +[**2108-1-14**] pod9/2 no acute events. started slow tube feeds via +gastric tube. continues w/ tpn via central line. continues on +antibiotics vanco/zosyn. +[**2108-1-15**] pod10/3 no acute events. continue tube feeds-advances to +goal (60cc/h), tpn. continues on antibiotics vanco/zosyn. +physical therapy consult. rehab screening. +[**date range (1) 45028**] pod11-12/4-5 no acute events, tube feeds at goal, tpn +d/cd. continues on vanco/zosyn. [**hospital 25403**] rehab bed. l leg +distal wound still draining, aced from forefoot-below knee. +[**2108-1-18**] pod12/6 no acute events. continues on vanco/zosyn. +physical therapy following. [**hospital 25403**] rehab bed. +[**2108-1-19**] pod13/6 d/c to rehab with one week of po bactrim. + + + ","PRIMARY: [Atherosclerosis of native arteries of the extremities with gangrene] +SECONDARY: [; Ulcer of heel and midfoot; Pneumonitis due to inhalation of food or vomitus; Other respiratory complications; Disruption of external operation (surgical) wound; Pneumonia, organism unspecified; Acute posthemorrhagic anemia; Pressure ulcer, stage III; Pressure ulcer, lower back; Unspecified essential hypertension; Gout, unspecified; Dysphagia, unspecified; Surgical operation with anastomosis, bypass, or graft, with natural or artificial tissues used as implant causing abnormal patient reaction, or later complication, without mention of misadventure at time of operation]"