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Updated ReadME with model information

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- ---
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- license: cc-by-nc-nd-4.0
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- ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ ---
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+ license: cc-by-nc-nd-4.0
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+ language:
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+ - en
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+ base_model: EleutherAI/pythia-410m
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+ library_name: transformers
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+ tags:
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+ - biology
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+ - scRNAseq
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+ ---
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+
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+ # Overview
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+ This is the C2S-Pythia-410m-cell-type-conditioned-cell-generation model, built on the Pythia-410m architecture developed
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+ by EleutherAI, fine-tuned using Cell2Sentence (C2S) on a comprehensive collection of single-cell RNA sequencing
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+ (scRNA-seq) datasets from CellxGene and the Human Cell Atlas. Cell2Sentence is a pioneering technique that adapts
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+ large language models (LLMs) to single-cell biology by converting scRNA-seq data into "cell sentences" — ordered
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+ sequences of gene names based on expression levels. This model is specifically trained for cell type-conditioned
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+ single-cell generation, enabling the generation of realistic single-cell profiles conditioned on specified cell
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+ types.
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+
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+ # Training Data
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+ This model was trained on over 57 million human and mouse cells gathered from over 800 single-cell RNA sequencing
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+ datasets from CellxGene and the Human Cell Atlas. This dataset covers a broad range of cell types and conditions
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+ from multiple tissues in both human and mouse.
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+
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+ # Tasks
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+ This model is designed for:
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+
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+ - Cell type-conditioned single-cell generation: Generating single-cell profiles conditioned on specific cell types, allowing for the creation of synthetic cells that reflect the gene expression patterns of targeted cell types.
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+
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+
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+ # Cell2Sentence Links
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+ - GitHub: https://github.com/vandijklab/cell2sentence
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+ - Paper: https://www.biorxiv.org/content/10.1101/2023.09.11.557287v3
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+
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+ # Pythia Links
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+ - Paper: https://arxiv.org/pdf/2304.01373
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+ - Hugging Face: https://huggingface.co/EleutherAI/pythia-410m