HAMMALE/rvl_cdip_OCR · Datasets at Hugging Face

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770	1,000	scientific report	[ ":", "‘", "\|", "SMOKING", "ANALYSIS", "i", "SAMPLE", "R-A011¢1)", "(#1213)-89", "RUN", "DATE", "1", "BRAND", "8Smm", "NE", "DATE", "RECEIVEN:", "06/13/89", "1", "¢", "DATE", "PREPARED!", "06/13/89", "DATE", "SHOKED", "06/14/89", "i", "MEAN", "WEIGHT/100", "4966", "NO.", "OF", "CIG", "FER", "FAD", "-", "CONTROL?", "5S", "PERCENT", "SELECTED", "¢", "FILTER", "0", "BUTT", "LENGTH", "(mn)?", "2360", "No.", "OF", "FADS", "Ps", "i", "REMARKS!", "Pe", "morsanses", "st)", "%", "REL", "95%", "CONF", "No.", "i", "bev", "so", "LIMIT", "OES.", "i", "WEIGHT", "0.491", "00062-1428", "0483", "-", "0-499", "5", "4", "PRESSURE", "DROP", "\|", "228.1", "18.31", "8.03", "220.6", "-", "235.725", "\|", "5", "TRY", "PART", "MAT", "!", "15.2", "1.23", "8.09", "13.7", "-", "16.7", "5", "ie", "NICOTINE", "0.87" ]	[ [ 78, 38, 79, 42 ], [ 40, 55, 41, 59 ], [ 741, 46, 743, 64 ], [ 237, 72, 346, 82 ], [ 364, 62, 489, 90 ], [ 760, 62, 763, 77 ], [ 59, 132, 109, 141 ], [ 170, 130, 244, 140 ], [ 257, 127, 337, 139 ], [ 398, 129, 421, 137 ], [ 432, 128, 464, 137 ], [ 511, 128, 513, 136 ], [ 60, 147, 100, 156 ], [ 170, 146, 202, 155 ], [ 213, 145, 228, 154 ], [ 399, 143, 430, 152 ], [ 441, 143, 513, 152 ], [ 534, 142, 601, 151 ], [ 743, 136, 744, 150 ], [ 759, 139, 763, 148 ], [ 399, 158, 431, 167 ], [ 441, 157, 513, 166 ], [ 535, 156, 602, 165 ], [ 399, 172, 431, 181 ], [ 441, 172, 490, 181 ], [ 535, 171, 602, 180 ], [ 759, 173, 763, 178 ], [ 60, 203, 93, 212 ], [ 103, 202, 186, 212 ], [ 257, 201, 289, 210 ], [ 399, 200, 420, 209 ], [ 433, 200, 448, 209 ], [ 458, 199, 482, 209 ], [ 492, 199, 516, 208 ], [ 526, 199, 550, 208 ], [ 561, 203, 567, 204 ], [ 578, 199, 643, 207 ], [ 664, 198, 670, 207 ], [ 61, 218, 118, 228 ], [ 128, 218, 195, 227 ], [ 233, 217, 236, 226 ], [ 577, 214, 628, 223 ], [ 664, 214, 671, 222 ], [ 61, 233, 93, 242 ], [ 103, 233, 152, 242 ], [ 164, 232, 236, 241 ], [ 257, 231, 289, 240 ], [ 399, 230, 421, 238 ], [ 433, 229, 448, 238 ], [ 458, 229, 491, 238 ], [ 641, 227, 662, 236 ], [ 744, 227, 746, 241 ], [ 61, 260, 125, 269 ], [ 197, 262, 210, 268 ], [ 223, 260, 295, 268 ], [ 349, 285, 373, 294 ], [ 417, 285, 424, 294 ], [ 434, 284, 457, 294 ], [ 519, 284, 543, 292 ], [ 553, 283, 585, 292 ], [ 639, 271, 661, 301 ], [ 745, 284, 747, 291 ], [ 350, 288, 374, 319 ], [ 426, 299, 441, 308 ], [ 528, 286, 569, 317 ], [ 630, 285, 670, 316 ], [ 745, 298, 747, 309 ], [ 62, 345, 111, 355 ], [ 249, 359, 289, 368 ], [ 334, 357, 458, 367 ], [ 494, 356, 535, 366 ], [ 545, 360, 552, 362 ], [ 563, 355, 604, 365 ], [ 657, 355, 664, 364 ], [ 746, 358, 763, 368 ], [ 63, 389, 128, 398 ], [ 139, 388, 171, 398 ], [ 761, 372, 763, 390 ], [ 250, 402, 290, 411 ], [ 335, 401, 373, 410 ], [ 427, 400, 459, 409 ], [ 495, 400, 536, 409 ], [ 546, 403, 553, 405 ], [ 563, 398, 665, 408 ], [ 747, 400, 748, 427 ], [ 761, 391, 764, 402 ], [ 63, 432, 87, 441 ], [ 97, 432, 128, 441 ], [ 139, 432, 162, 440 ], [ 24, 448, 25, 452 ], [ 250, 433, 291, 464 ], [ 334, 432, 375, 463 ], [ 418, 431, 459, 462 ], [ 505, 442, 536, 451 ], [ 546, 446, 553, 447 ], [ 573, 442, 605, 451 ], [ 659, 441, 665, 450 ], [ 747, 440, 763, 454 ], [ 64, 474, 129, 483 ], [ 259, 487, 292, 497 ] ]	[ ": ‘ \| SMOKING ANALYSIS i SAMPLE R-A011¢1) (#1213)-89 RUN DATE 1 BRAND 8Smm NE DATE RECEIVEN: 06/13/89 1 ¢ DATE PREPARED! 06/13/89 DATE SHOKED 06/14/89 i MEAN WEIGHT/100 4966 NO. OF CIG FER FAD - CONTROL? 5S PERCENT SELECTED ¢ FILTER 0 BUTT LENGTH (mn)? 2360 No. OF FADS Ps i REMARKS! Pe morsanses st) % REL 95% CONF No. i bev so LIMIT OES. i WEIGHT 0.491 00062-1428 0483 - 0-499 5 4 PRESSURE DROP \| 228.1 18.31 8.03 220.6 - 235.725 \| 5 TRY PART MAT ! 15.2 1.23 8.09 13.7 - 16.7 5 ie NICOTINE 0.87 0.038 4.42 0.82 - 0.92 5 fi CORRECTED PART MAT 14.3 4.19 12.9 - 15.8 8 CARBON HONOXIDE (ms/eis)? i 8.8 0.58 6652 98 5 i PUFF COUNT ¢ \| a7 0.24 5.03 aa 5.0 s \\ XN \\ 8 & & x 8" ]	[ [ 24, 38, 764, 864 ] ]	5
754	1,000	scientific publication	[ "Clinical", "and", "Molecular", "Techniques", "for", "Diagnosis", "and", "Monitoring", "of", "Prostatic", "Cancer", "C.", "S.", "FOSTER,", "MD,", "PHD,", "MRCPatH,", "AND", "P.", "D.", "ABEL,", "CuM", "FRCS", "Part2", "of", "this", "ymposiam", "reviews", "of", "prostate", "in", "prostatic", "biopsy", "specimens", "and", "has", "evaluated", "the", "cancer", "apd", "other", "than", "conventional", "computer-based", "image", "systems", "currenly", "avai", "that", "rely", "either", "on", "specialized", "inscrumen-", "able", "for", "analyzing", "prostate", "cancer.", "That", "clearly", "The", "majority", "of", "such", "techniques", "already", "have", "been", "ad-", "puters", "for", "morphometric", "analysis", "with", "an", "evaluation", "of", "dressed", "opies", "inthis", "However,", "methods", "currently", "uvalable,", "with", "ther", "prob", "Contributions", "to", "the", "averall", "understanding", "of", "For", "exauiple,", "ifs", "image", "analysis", "system" ]	[ [ 104, 64, 183, 82 ], [ 191, 65, 231, 82 ], [ 240, 65, 345, 82 ], [ 352, 64, 471, 84 ], [ 105, 89, 132, 106 ], [ 139, 90, 239, 113 ], [ 247, 89, 287, 107 ], [ 296, 89, 406, 112 ], [ 105, 115, 124, 131 ], [ 133, 115, 221, 132 ], [ 229, 115, 306, 131 ], [ 104, 156, 114, 167 ], [ 127, 156, 133, 168 ], [ 146, 156, 198, 169 ], [ 207, 157, 232, 169 ], [ 241, 156, 269, 168 ], [ 278, 155, 341, 168 ], [ 350, 156, 379, 167 ], [ 388, 156, 394, 164 ], [ 407, 156, 416, 167 ], [ 429, 156, 464, 168 ], [ 473, 156, 503, 167 ], [ 512, 156, 545, 167 ], [ 107, 195, 135, 204 ], [ 135, 181, 151, 213 ], [ 155, 196, 172, 204 ], [ 175, 198, 272, 208 ], [ 233, 181, 271, 213 ], [ 311, 181, 325, 213 ], [ 329, 194, 371, 207 ], [ 394, 198, 402, 203 ], [ 410, 196, 452, 207 ], [ 462, 195, 495, 207 ], [ 503, 197, 554, 206 ], [ 564, 195, 580, 203 ], [ 587, 195, 603, 203 ], [ 610, 195, 659, 203 ], [ 667, 195, 682, 204 ], [ 83, 212, 115, 217 ], [ 162, 209, 181, 218 ], [ 245, 209, 273, 218 ], [ 277, 208, 299, 217 ], [ 304, 209, 370, 217 ], [ 394, 208, 478, 220 ], [ 483, 211, 513, 220 ], [ 561, 210, 599, 217 ], [ 604, 208, 650, 218 ], [ 656, 208, 678, 217 ], [ 154, 223, 173, 232 ], [ 179, 223, 197, 232 ], [ 202, 208, 231, 240 ], [ 236, 226, 245, 231 ], [ 254, 222, 309, 234 ], [ 315, 225, 366, 231 ], [ 394, 223, 414, 231 ], [ 420, 223, 433, 230 ], [ 439, 222, 489, 233 ], [ 494, 224, 535, 234 ], [ 540, 225, 572, 230 ], [ 585, 222, 605, 230 ], [ 649, 222, 682, 232 ], [ 85, 250, 99, 259 ], [ 107, 253, 149, 262 ], [ 154, 250, 165, 259 ], [ 169, 250, 192, 259 ], [ 197, 250, 252, 262 ], [ 257, 250, 294, 259 ], [ 299, 250, 322, 258 ], [ 326, 250, 350, 258 ], [ 356, 250, 371, 258 ], [ 394, 252, 426, 259 ], [ 431, 250, 446, 258 ], [ 450, 250, 525, 261 ], [ 530, 250, 569, 259 ], [ 573, 249, 594, 258 ], [ 599, 252, 610, 258 ], [ 614, 250, 667, 258 ], [ 672, 250, 682, 258 ], [ 83, 265, 120, 272 ], [ 191, 267, 220, 276 ], [ 225, 264, 254, 272 ], [ 322, 264, 366, 272 ], [ 394, 264, 438, 272 ], [ 443, 264, 489, 275 ], [ 496, 263, 540, 272 ], [ 598, 266, 619, 272 ], [ 625, 263, 649, 272 ], [ 654, 264, 678, 275 ], [ 83, 292, 153, 300 ], [ 158, 294, 168, 301 ], [ 173, 292, 188, 301 ], [ 193, 292, 228, 300 ], [ 233, 294, 309, 303 ], [ 314, 291, 323, 300 ], [ 394, 291, 412, 300 ], [ 415, 291, 462, 303 ], [ 466, 291, 481, 300 ], [ 573, 294, 600, 302 ], [ 606, 291, 645, 300 ], [ 648, 293, 688, 305 ] ]	[ "Clinical and Molecular Techniques for Diagnosis and Monitoring of Prostatic Cancer C. S. FOSTER, MD, PHD, MRCPatH, AND P. D. ABEL, CuM FRCS Part2 of this ymposiam reviews of prostate in prostatic biopsy specimens and has evaluated the cancer apd other than conventional computer-based image systems currenly avai that rely either on specialized inscrumen- able for analyzing prostate cancer. That clearly The majority of such techniques already have been ad- puters for morphometric analysis with an evaluation of dressed opies inthis However, methods currently uvalable, with ther prob Contributions to the averall understanding of For exauiple, ifs image analysis system Consideration of features, crunpredictable nature, then the expense ofa dedicated ceed tt compauble software programs able To un on come mercially available appears to be the TISSUE MORPHOMETRY sisted. acquisition of morphometric data is laborious, these various aspects of prostae measurements of tumor volume provides an en- examined, Although hanced assessment of the of individual oF [tom autopsy material! other nave examined volumetric i biopsy Although there ig and have shown these sb to be important of NHK shee parler. her poten and ee ay prostatic resection, the ratiu of prostatic chippings con- P this approach shoal be adopted with cautious ining cancer to the wal number of chippings removed of the limitations of the numerical data ob- stage and volume.’ Recently, tis technique ta relative areas of cancer IMAGING TECHNIQUES resected prostatic chippings. x! Image phasiced the value of camputer-issisted morphometry Magnetic Reserance Imaging coupled with powerful data processing computer soft-etecuon of small and localized malignancies mare have renewed in morphologic provides the best opportunity for cure. To such grading systems and have shown these fo be a more accurate appraisal of te size, location, and extent and, hence, objective of obtaining of the primary disease iy uandatory. In this respect detailed data with which co predict the and cransrectal ultrasound burn prostate cancer In this symposium, (TRUS) of the prostate are approximately 60% accurate Dalton Hiss 1993) has aderessed\| OF potentially greater valne magnetic resonance ine a ‘ar and Walach provide compelling evidence that while From the Departments of Histopathology and Surgery, Wlagnetic resonance imaging with current levels of res- School, UR, olution’ at 300 ym fapproximately 20 cell st ‘ics one snd repre to provides acceptable images that accurately enable the ‘MD, PhD, MRCPath, Department of Ehstopathology. Roval Post- location of small fesions, further refinement of resolu- Mea tion wll this toward the level of Up 1992 by WB, Sander Compan Furthermore, magoelic resonance a troscopie of issue components nd 305 50628402" ]	[ [ 76, 64, 688, 997 ] ]	6
762	1,000	resume	[ "610", "BATTA", "GORI", "Franklin", "Institute", "Policy", "Analysis", "Center", "1320", "Fenwick", "Lane", "Silver", "Spring,", "MD", "20910", "(301)", "585-8722", "EXPERIENCE/BACKGROUND", "0", "Biology,", "toxicology,", "epidemiology,", "and", "management.", "©", "Played", "key", "roles", "in", "the", "successful", "passage", "of", "the", "1970", "Cancer", "Act", "and", "subsequent", "appropriations.", "Planned", "and", "managec", "research", "and", "intervention", "programs", "of", "national", "and", "international", "scope,", "establishing", "consensus", "priorities", "in", "cancer", "causation,", "prevention", "and", "control,", "and", "patient", "managenent.", "0", "Exerted", "national", "leadership", "in", "carcinogenesis", "research,", "methods", "and", "priorities", "of", "carcinogen", "testing,", "epidemiology.", "sncking", "and", "health,", "nutrition,", "ozone", "depletion", "and", "ultraviolet", "radiation,", "cost", "and", "benefit", "analysis", "of", "prevention", "policies,", "safety", "and", "carcinogen", "regulation.", "©", "Firsthand" ]	[ [ 304, 86, 325, 96 ], [ 332, 86, 365, 96 ], [ 373, 85, 398, 95 ], [ 105, 127, 158, 137 ], [ 168, 126, 227, 137 ], [ 105, 140, 145, 153 ], [ 153, 140, 206, 153 ], [ 215, 140, 255, 150 ], [ 106, 154, 131, 165 ], [ 140, 154, 185, 164 ], [ 194, 155, 221, 164 ], [ 105, 168, 145, 178 ], [ 153, 168, 199, 180 ], [ 208, 168, 221, 177 ], [ 229, 168, 262, 178 ], [ 106, 180, 137, 194 ], [ 146, 182, 200, 192 ], [ 105, 222, 248, 233 ], [ 118, 265, 124, 273 ], [ 139, 262, 192, 275 ], [ 201, 262, 275, 275 ], [ 284, 262, 371, 275 ], [ 379, 262, 399, 272 ], [ 406, 262, 479, 274 ], [ 119, 292, 124, 300 ], [ 139, 290, 178, 302 ], [ 187, 290, 207, 302 ], [ 215, 289, 248, 300 ], [ 257, 292, 269, 299 ], [ 277, 290, 296, 299 ], [ 305, 289, 369, 299 ], [ 379, 291, 426, 301 ], [ 434, 289, 447, 298 ], [ 455, 289, 474, 298 ], [ 481, 288, 508, 298 ], [ 516, 288, 555, 298 ], [ 563, 288, 582, 298 ], [ 139, 304, 158, 313 ], [ 166, 303, 234, 315 ], [ 242, 303, 343, 315 ], [ 359, 302, 406, 312 ], [ 413, 302, 433, 312 ], [ 440, 305, 487, 314 ], [ 495, 302, 548, 312 ], [ 556, 302, 575, 312 ], [ 140, 317, 220, 326 ], [ 229, 319, 282, 329 ], [ 290, 316, 303, 326 ], [ 311, 316, 363, 326 ], [ 372, 316, 392, 326 ], [ 400, 316, 485, 326 ], [ 495, 318, 534, 328 ], [ 139, 330, 220, 342 ], [ 229, 333, 289, 340 ], [ 297, 330, 364, 342 ], [ 373, 333, 385, 340 ], [ 393, 332, 433, 340 ], [ 441, 330, 506, 341 ], [ 516, 330, 582, 341 ], [ 139, 344, 158, 354 ], [ 166, 343, 220, 355 ], [ 229, 344, 248, 354 ], [ 256, 344, 303, 356 ], [ 310, 344, 383, 356 ], [ 119, 374, 124, 381 ], [ 140, 371, 185, 381 ], [ 194, 370, 246, 381 ], [ 256, 370, 324, 383 ], [ 332, 373, 344, 380 ], [ 352, 370, 446, 383 ], [ 455, 370, 513, 381 ], [ 521, 370, 568, 380 ], [ 139, 384, 158, 394 ], [ 166, 384, 234, 396 ], [ 242, 384, 255, 394 ], [ 263, 384, 331, 396 ], [ 338, 384, 391, 396 ], [ 399, 383, 486, 406 ], [ 495, 383, 541, 396 ], [ 549, 383, 568, 393 ], [ 139, 397, 185, 409 ], [ 194, 398, 261, 409 ], [ 269, 400, 303, 407 ], [ 311, 396, 371, 407 ], [ 379, 397, 399, 406 ], [ 406, 396, 474, 406 ], [ 488, 396, 554, 407 ], [ 563, 396, 589, 406 ], [ 139, 411, 158, 422 ], [ 166, 411, 214, 421 ], [ 222, 411, 275, 423 ], [ 283, 411, 296, 421 ], [ 304, 410, 371, 423 ], [ 379, 410, 439, 422 ], [ 448, 409, 486, 422 ], [ 495, 409, 514, 419 ], [ 522, 409, 589, 422 ], [ 140, 425, 211, 437 ], [ 119, 454, 124, 461 ], [ 140, 451, 199, 461 ] ]	[ "610 BATTA GORI Franklin Institute Policy Analysis Center 1320 Fenwick Lane Silver Spring, MD 20910 (301) 585-8722 EXPERIENCE/BACKGROUND 0 Biology, toxicology, epidemiology, and management. © Played key roles in the successful passage of the 1970 Cancer Act and subsequent appropriations. Planned and managec research and intervention programs of national and international scope, establishing consensus priorities in cancer causation, prevention and control, and patient managenent. 0 Exerted national leadership in carcinogenesis research, methods and priorities of carcinogen testing, epidemiology. sncking and health, nutrition, ozone depletion and ultraviolet radiation, cost and benefit analysis of prevention policies, safety and carcinogen regulation. © Firsthand understanding of federal research and regulatory agencies, the budgetary and appropriations process, Congress and legislative operations, the diversity of motivation in private enterprise, academia, advocacy groups, and the pluralistic soctoeconomic reality. Extensive consulting experience with petrochemical and chemical industries, pharmaceutical manufacturers, cosmetic and food industries, and mining. © Direct multilingual contacts with parallel issues and organizations in Europe. Nurerous appearances at congressional hearings. Congressional contacts and familiarity with the lay and scientific media. 1" ]	[ [ 105, 85, 594, 852 ] ]	14
762	1,000	invoice	[ "ag", "We", "mvoce", "a", "-", "alls", "City", "_", "ae", "ag", "193,", "5", "Com", "&", "Company", "—", "1427420", "Louisville", "gun", "Be", "\|", "eee", "SUSE", "(902)", "5007375", "DATE:", "October", "5,", "1979", "=", "eae", "a", "ge.", "3", "Brown", "ee", "2", "L", "4600", "W,", "Hil", "St.", "\|", "Kentucky", "40202", "aos", "\|", "Glenda", "SO", "Hyatt", "\|", "Se", "we", "ook", "“oferta", "an", "RENTAL", "\|", "a", "“12", "\|", "Welt", "safelock", "stands", "16}00", "\|", "3]", "1", "-\|", "extra", "castored", "stand", "i", "£]", "1", "lanp", "&", "\|", "\|", "“\|", "trouperette", "ITI", "w/spare", "lamp", "az}", "1", "3/4\"", "VIR", "w/monitor", "on", "cart", "a", "aes", "260}00", "\|", "8", "x", "8", "sereen", "Mike" ]	[ [ 394, 13, 406, 37 ], [ 8, 32, 51, 63 ], [ 446, 44, 497, 53 ], [ 111, 67, 141, 86 ], [ 186, 87, 194, 88 ], [ 221, 45, 277, 93 ], [ 286, 50, 333, 95 ], [ 354, 85, 361, 86 ], [ 524, 61, 543, 93 ], [ 542, 61, 564, 93 ], [ 608, 70, 645, 96 ], [ 150, 89, 167, 115 ], [ 314, 84, 361, 92 ], [ 654, 73, 668, 110 ], [ 319, 93, 397, 122 ], [ 410, 89, 427, 136 ], [ 229, 134, 267, 141 ], [ 192, 144, 277, 179 ], [ 554, 158, 576, 165 ], [ 627, 150, 649, 171 ], [ 665, 149, 678, 168 ], [ 12, 175, 37, 194 ], [ 52, 179, 107, 200 ], [ 236, 167, 259, 194 ], [ 260, 167, 305, 194 ], [ 428, 176, 472, 188 ], [ 488, 175, 545, 186 ], [ 554, 175, 567, 189 ], [ 579, 175, 610, 187 ], [ 641, 170, 678, 176 ], [ 330, 189, 353, 195 ], [ 515, 191, 545, 203 ], [ 625, 190, 656, 204 ], [ 23, 198, 29, 219 ], [ 37, 194, 86, 225 ], [ 388, 206, 437, 211 ], [ 506, 204, 516, 214 ], [ 23, 222, 29, 230 ], [ 46, 221, 77, 233 ], [ 86, 222, 100, 233 ], [ 111, 222, 143, 232 ], [ 152, 221, 173, 232 ], [ 678, 222, 679, 228 ], [ 144, 236, 209, 248 ], [ 218, 235, 257, 247 ], [ 517, 234, 571, 240 ], [ 678, 230, 679, 241 ], [ 95, 251, 143, 262 ], [ 313, 262, 319, 264 ], [ 381, 248, 421, 262 ], [ 678, 249, 679, 266 ], [ 391, 268, 432, 285 ], [ 46, 317, 60, 328 ], [ 120, 317, 136, 328 ], [ 169, 314, 225, 329 ], [ 596, 314, 627, 325 ], [ 219, 367, 267, 378 ], [ 508, 357, 510, 373 ], [ 636, 370, 663, 373 ], [ 21, 382, 54, 394 ], [ 70, 373, 85, 402 ], [ 88, 383, 119, 394 ], [ 130, 382, 194, 394 ], [ 203, 382, 251, 393 ], [ 622, 379, 662, 390 ], [ 679, 365, 681, 398 ], [ 23, 396, 29, 408 ], [ 48, 398, 53, 408 ], [ 60, 387, 84, 418 ], [ 89, 398, 128, 408 ], [ 137, 397, 202, 408 ], [ 211, 397, 251, 408 ], [ 371, 395, 401, 403 ], [ 23, 409, 29, 424 ], [ 48, 413, 53, 423 ], [ 244, 411, 276, 424 ], [ 285, 411, 293, 422 ], [ 476, 415, 478, 419 ], [ 679, 399, 681, 422 ], [ 67, 418, 81, 444 ], [ 88, 426, 177, 440 ], [ 187, 425, 210, 437 ], [ 219, 424, 276, 439 ], [ 285, 425, 317, 438 ], [ 15, 440, 29, 457 ], [ 48, 442, 53, 452 ], [ 89, 440, 119, 454 ], [ 129, 441, 154, 452 ], [ 162, 440, 236, 454 ], [ 244, 443, 260, 451 ], [ 269, 440, 301, 451 ], [ 451, 444, 461, 450 ], [ 523, 441, 546, 450 ], [ 615, 438, 663, 449 ], [ 680, 427, 681, 452 ], [ 88, 457, 96, 467 ], [ 104, 458, 113, 466 ], [ 121, 456, 128, 467 ], [ 138, 458, 187, 466 ], [ 248, 457, 260, 460 ] ]	[ "ag We mvoce a - alls City _ ae ag 193, 5 Com & Company — 1427420 Louisville gun Be \| eee SUSE (902) 5007375 DATE: October 5, 1979 = eae a ge. 3 Brown ee 2 L 4600 W, Hil St. \| Kentucky 40202 aos \| Glenda SO Hyatt \| Se we ook “oferta an RENTAL \| a “12 \| Welt safelock stands 16}00 \| 3] 1 -\| extra castored stand i £] 1 lanp & \| \| “\| trouperette ITI w/spare lamp az} 1 3/4\" VIR w/monitor on cart a aes 260}00 \| 8 x 8 sereen Mike Ro vay i 24100 4 Impedence match box w/cables, mike, . j 71/00 \| lel 43/04 \| Bie “ORIGINAL \| [APPROVED For \| 7 jest ql \| SEE SEY! [a as mms one ying be ee pn ey Se \| uae veer De \| the \| Pie Sx oe ater PR \| RECT oy pare PAR es SEE" ]	[ [ 2, 13, 686, 917 ] ]	11
1,000	754	email	[ "Tonyd", "From: Tuckcr;", "(LHC)", "To;ltlcrann, Palti F", "CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M,", "BCC:", "Primary Date: 4/23/1997 2.16.01 PM", "Last Modified Date: 1997-Dec-15 08.15.59", "Last Touched Date:", "Sent Date: 1997-Apr-23 13.31.0", "Received Datc: 1997-Apr-23 14.16.01", "Subject:", "Attachments:", "MRIAUDXLS", "My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs", "MRIAUDXLS", "3925 in MRIAUD XLS ]]", "8", "8", "RJR24041434", "70004 1403" ]	[ [ 197, 83, 235, 104 ], [ 111, 85, 197, 101 ], [ 237, 85, 279, 101 ], [ 111, 101, 237, 119 ], [ 113, 117, 503, 137 ], [ 111, 135, 151, 153 ], [ 110, 151, 337, 171 ], [ 111, 169, 371, 189 ], [ 111, 189, 235, 205 ], [ 111, 205, 311, 223 ], [ 111, 223, 337, 241 ], [ 110, 238, 165, 258 ], [ 111, 274, 197, 290 ], [ 109, 289, 203, 309 ], [ 109, 359, 539, 379 ], [ 123, 427, 215, 447 ], [ 221, 429, 375, 449 ], [ 687, 799, 703, 847 ], [ 683, 852, 703, 893 ], [ 19, 943, 115, 961 ], [ 19, 961, 99, 979 ] ]	[ "From: Tuckcr; Tonyd (LHC) To;ltlcrann, Palti F CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M, BCC: Primary Date: 4/23/1997 2.16.01 PM Last Modified Date: 1997-Dec-15 08.15.59 Last Touched Date: Sent Date: 1997-Apr-23 13.31.0 Received Datc: 1997-Apr-23 14.16.01 Subject:", "Attachments: MRIAUDXLS", "My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs", "MRIAUDXLS 3925 in MRIAUD XLS ]]", "8 8", "RJR24041434 70004 1403" ]	[ [ 110, 83, 503, 258 ], [ 109, 274, 203, 309 ], [ 109, 359, 539, 379 ], [ 123, 427, 375, 449 ], [ 683, 799, 703, 893 ], [ 19, 943, 115, 979 ] ]	2
777	1,000	news article	[ "‘the", "decision", "of", "the", "Aneriean", "Heart", "Association", "to", "Join", "tn", "educatloral", "campatene", "to", "discourage", "vas", "reported", "in", "and", "ty.", "the", "wire", "services.", "Sone", "stories", "a", "round-up", "of", "other", "recent.", "affecting", "the", "tobacco", "industry", "set", "S", "TRIBUNE", "The", "Words", "Get", "YORK", "nm", "New", "York,", "N.Y.", "I", ".", ".", "June", "9,", "1963", "rt", "Associz", "eart", "Association", "mokm,", "arnm.", "few", "York", "New", "York,", "June", "9,", "1963", "between", "cigarette", "smoking", "shoul", "be", "Heart", "Society", "Maps:", "none", "professions.”", "Henst", "Assocation,", "July,", "1960.", "Drive", "on", "Cigarettes", "er", "do", "Tiere", "of", "the.", "harmfut", "effects", "of", "cigarette", "smoking", "to", "warrant", "the", "By", "ALFRED", "F,", "ue", "ands", "and", "and" ]	[ [ 121, 79, 140, 87 ], [ 148, 78, 201, 87 ], [ 210, 78, 222, 87 ], [ 230, 79, 249, 87 ], [ 257, 79, 310, 87 ], [ 319, 79, 352, 87 ], [ 359, 79, 434, 87 ], [ 442, 79, 455, 87 ], [ 463, 79, 488, 90 ], [ 503, 81, 509, 87 ], [ 517, 79, 591, 88 ], [ 600, 80, 660, 91 ], [ 121, 94, 134, 101 ], [ 142, 93, 208, 103 ], [ 270, 95, 290, 101 ], [ 299, 92, 352, 103 ], [ 360, 93, 373, 101 ], [ 544, 94, 564, 102 ], [ 572, 94, 584, 104 ], [ 593, 94, 612, 102 ], [ 121, 109, 147, 115 ], [ 155, 107, 214, 115 ], [ 230, 107, 255, 116 ], [ 264, 107, 310, 115 ], [ 380, 109, 386, 116 ], [ 394, 107, 448, 118 ], [ 456, 107, 469, 116 ], [ 476, 108, 509, 116 ], [ 517, 108, 556, 116 ], [ 121, 121, 181, 131 ], [ 189, 121, 208, 129 ], [ 217, 121, 263, 129 ], [ 272, 121, 324, 131 ], [ 208, 155, 210, 158 ], [ 241, 155, 244, 158 ], [ 469, 155, 502, 164 ], [ 103, 154, 132, 168 ], [ 145, 155, 190, 169 ], [ 199, 155, 226, 169 ], [ 372, 155, 399, 164 ], [ 455, 155, 467, 164 ], [ 346, 170, 365, 179 ], [ 372, 169, 404, 181 ], [ 414, 170, 439, 179 ], [ 76, 185, 86, 213 ], [ 257, 188, 262, 193 ], [ 294, 188, 299, 194 ], [ 345, 184, 372, 193 ], [ 380, 184, 391, 195 ], [ 401, 182, 426, 195 ], [ 141, 196, 147, 202 ], [ 183, 186, 271, 214 ], [ 101, 192, 159, 214 ], [ 200, 193, 335, 215 ], [ 92, 239, 178, 256 ], [ 242, 240, 318, 258 ], [ 427, 239, 446, 248 ], [ 455, 239, 474, 248 ], [ 427, 253, 447, 262 ], [ 454, 253, 486, 265 ], [ 427, 268, 453, 276 ], [ 461, 268, 472, 279 ], [ 482, 266, 507, 278 ], [ 189, 278, 230, 288 ], [ 238, 280, 282, 290 ], [ 291, 280, 332, 290 ], [ 242, 291, 274, 312 ], [ 278, 278, 286, 316 ], [ 410, 282, 457, 315 ], [ 463, 282, 516, 315 ], [ 519, 282, 565, 315 ], [ 664, 300, 697, 308 ], [ 74, 314, 139, 323 ], [ 206, 306, 225, 333 ], [ 229, 306, 281, 333 ], [ 283, 306, 308, 333 ], [ 312, 306, 330, 333 ], [ 430, 312, 467, 327 ], [ 471, 319, 486, 328 ], [ 490, 313, 560, 332 ], [ 676, 308, 685, 339 ], [ 692, 308, 708, 339 ], [ 84, 332, 121, 354 ], [ 252, 334, 262, 344 ], [ 270, 334, 285, 343 ], [ 293, 334, 334, 345 ], [ 102, 345, 135, 354 ], [ 141, 345, 151, 355 ], [ 157, 346, 201, 354 ], [ 207, 348, 249, 356 ], [ 256, 347, 264, 354 ], [ 271, 347, 312, 355 ], [ 319, 346, 333, 355 ], [ 438, 350, 449, 359 ], [ 454, 350, 544, 358 ], [ 494, 341, 509, 368 ], [ 690, 349, 710, 362 ], [ 225, 357, 260, 366 ], [ 316, 358, 334, 367 ], [ 431, 361, 447, 368 ] ]	[ "‘the decision of the Aneriean Heart Association to Join tn educatloral campatene to discourage vas reported in and ty. the wire services. Sone stories a round-up of other recent. affecting the tobacco industry set S TRIBUNE The Words Get YORK nm New York, N.Y. I . . June 9, 1963 rt Associz eart Association mokm, arnm. few York New York, June 9, 1963 between cigarette smoking shoul be Heart Society Maps: none professions.” Henst Assocation, July, 1960. Drive on Cigarettes er do Tiere of the. harmfut effects of cigarette smoking to warrant the By ALFRED F, ue ands and and Amen set Ata ih, Chapter vung with the hee ta rng tb, hee smoking by the general public.” ‘emphasis on teen-agers. (Of attacks and strokes in Heat Asin, ytd. tcc ARG poard of directors An ad hoc committee of fone rm tear eae ae ee her aoe sed Toons ‘against smoking more strongly. Throwing out most of the groups.” The associa. NODS the Heart heath groups The associ’ urged Mat ete ge Mein ae, st ike rt Hae elution by the Association's board of directors meeting ‘The move marks the first More and larger longitudinal ted a aes etn ume utr AES Ja ) Shh Sa patie nan agency, naar, Reportedly, the AHA had been on the verge of launch- ded to wage a public campaign artery and other cartio. ing a public campaign against cigarette smoking following ‘on cone ‘a study in 1960 that showed that smokers are In 50 to 150 ‘A spokesman said that the , Possible of eter Sine at a a Sng rans pen rte ia gue ihe weft stout seareh Commitee sult fate ws a th Come cold Sl ea thas become available which contradicts or invalidates the the heart yesterday myocardial infarction and groupe ion? Officials of the Tobacco Industry Research Committee Jn 3960, the association of duration and in- spokesmen for the industry in the eontroversy— A report indicating that evidenc: censity of smoking on the risk Ses ore One, nd a ory SRS som acted ty and Gisease do not prove board reviews constituents of tobacco men have said in the past: \"Statistics never PE on the heart and blood vesse'= ‘killed anybody. ‘come shice £860, of animals and humans and ov ‘In the case of lung cancer it is usually assumed that Are Cited such disease processes ax ex: cigarette smoke may injure lung tissues, But a biological “No evidence has become perimental wR ‘Explanation for the link between heart ailments and since 2 Studien of patients tn our oir othe AA 1061 ne $B vn ANA Me on qos Se hoon ey ballets tat sucking Winger the Pe, Sis toe te A ac Hoe Sangeet an eins \| to sue a tobacco company for the pert smoking ls Cigar ‘ortaty trom coronary N, Juan Bove ee ean Hints cies) he tune see sump on Wall Say sani Pity New York City Health SHEER, ees op james urged doctors to persuade patlents to stop smoking vessels theparms and legs seph T. Doyle of Albany and He warned that ony ebe of 15 lung cancer is now being saved and said: “If you (doctors! can that 0 Pre Tr on Cues Fu sea ter ee rst" ]	[ [ 55, 78, 730, 1000 ] ]	9
1,000	754	news article	[ "DRAFT", "AJS/ em", "3/24/81", "Proposed Response", "Press", "and", "Other", "Inquiries Regarding Publication by", "the", "Laboratory", "FTC", "FTC", "Test", "Results", "Carbon", "Yields", "Monoxide", "ofCigarettes", "a7", "Wih", "Lorillara", "the", "Tobacco", "statement urging", "Institute", "in interpreting", "caution", "the", "significance", "the Federal", "Commission baboratory", "Trade", "test", "results", "carbon monoxide", "yields of", "cigarettes", "ished", "publ_", "this", "week", "the", "Commission .", "Lorillard", "issuing", "spokesperson", "noted", "that", "chese", "test", "results", "the", "FTC", "nas attempted,", "without scientific", "proof", "to leave", "the", "impression", "that", "monoxide", "from", "carpon", "cigarette", "significant", "smoke", "represents", "threat", "human", "However ,", "health.", "Lorillard # rtodentative pointed", "Ere", "out", "that", "the", "relevant scientific literature", "this regard", "#t", "the great", "of scientific evidence", "inconclusive", "and", "body", "available", "indicates", "thc small", "the", "subject", "that", "amount", "monoxide generated", "carbon", "by cigarettes", "an insigni-", "ficant part of", "total", "the", "carbon", "monoxide", "the atmosphere", "L", "#4#" ]	[ [ 524, 98, 631, 220 ], [ 116, 155, 173, 173 ], [ 117, 171, 179, 187 ], [ 211, 240, 355, 258 ], [ 385, 243, 431, 257 ], [ 435, 243, 463, 257 ], [ 469, 243, 513, 257 ], [ 219, 255, 505, 273 ], [ 203, 269, 231, 283 ], [ 327, 270, 413, 287 ], [ 235, 271, 265, 283 ], [ 293, 271, 323, 285 ], [ 419, 271, 455, 285 ], [ 461, 271, 523, 287 ], [ 227, 283, 281, 297 ], [ 361, 283, 413, 299 ], [ 285, 285, 355, 299 ], [ 419, 285, 531, 301 ], [ 255, 301, 285, 315 ], [ 465, 311, 503, 327 ], [ 169, 325, 247, 339 ], [ 477, 327, 505, 341 ], [ 511, 327, 573, 341 ], [ 217, 350, 355, 371 ], [ 119, 353, 197, 367 ], [ 427, 354, 555, 370 ], [ 359, 355, 421, 369 ], [ 561, 355, 589, 369 ], [ 116, 377, 221, 397 ], [ 251, 381, 345, 397 ], [ 401, 381, 583, 399 ], [ 351, 383, 397, 397 ], [ 119, 409, 155, 423 ], [ 159, 409, 221, 423 ], [ 251, 409, 379, 425 ], [ 385, 409, 463, 427 ], [ 469, 411, 555, 427 ], [ 150, 434, 197, 452 ], [ 116, 436, 154, 449 ], [ 201, 437, 237, 451 ], [ 243, 437, 279, 451 ], [ 311, 437, 339, 451 ], [ 343, 437, 437, 453 ], [ 167, 477, 247, 493 ], [ 492, 477, 555, 497 ], [ 267, 479, 371, 495 ], [ 375, 479, 421, 493 ], [ 427, 479, 463, 493 ], [ 561, 481, 605, 495 ], [ 119, 507, 155, 521 ], [ 159, 507, 221, 521 ], [ 235, 507, 263, 521 ], [ 267, 507, 297, 521 ], [ 301, 507, 419, 523 ], [ 425, 507, 581, 523 ], [ 117, 533, 163, 549 ], [ 177, 533, 245, 549 ], [ 251, 535, 279, 549 ], [ 285, 535, 371, 551 ], [ 377, 535, 413, 549 ], [ 475, 535, 547, 549 ], [ 551, 535, 589, 549 ], [ 417, 537, 471, 549 ], [ 117, 561, 195, 577 ], [ 359, 561, 455, 579 ], [ 201, 563, 245, 577 ], [ 251, 563, 337, 579 ], [ 461, 563, 513, 577 ], [ 543, 563, 589, 577 ], [ 190, 588, 261, 605 ], [ 117, 589, 177, 603 ], [ 301, 589, 571, 607 ], [ 269, 591, 295, 605 ], [ 577, 591, 605, 605 ], [ 119, 617, 155, 631 ], [ 159, 617, 187, 631 ], [ 191, 617, 445, 633 ], [ 477, 617, 571, 635 ], [ 257, 631, 295, 647 ], [ 267, 644, 345, 661 ], [ 393, 644, 579, 661 ], [ 117, 645, 221, 659 ], [ 233, 645, 263, 659 ], [ 351, 645, 387, 661 ], [ 117, 671, 195, 687 ], [ 325, 671, 403, 689 ], [ 451, 672, 529, 689 ], [ 227, 673, 253, 687 ], [ 259, 673, 321, 689 ], [ 409, 673, 445, 689 ], [ 533, 675, 587, 689 ], [ 199, 700, 353, 717 ], [ 141, 701, 195, 715 ], [ 359, 701, 471, 717 ], [ 501, 701, 595, 717 ], [ 117, 727, 237, 745 ], [ 277, 727, 319, 743 ], [ 243, 729, 271, 743 ], [ 325, 729, 379, 743 ], [ 383, 729, 453, 743 ], [ 485, 729, 605, 745 ], [ 625, 751, 645, 839 ], [ 323, 785, 361, 799 ] ]	[ "AJS/ em DRAFT 3/24/81 Proposed Response Press and Other Inquiries Regarding Publication by the FTC FTC Laboratory Test Results Carbon Monoxide Yields ofCigarettes a7 Wih Lorillara the Tobacco Institute statement urging caution in interpreting the significance the Federal Trade Commission baboratory", "test results", "carbon monoxide yields of cigarettes", "publ_ ished this week", "the Commission .", "Lorillard", "issuing chese", "spokesperson noted that", "test results the FTC nas attempted, without scientific", "proof to leave the impression that carpon monoxide from", "cigarette smoke represents", "significant threat", "human", "health. However , Ere Lorillard # rtodentative pointed out", "that the relevant scientific literature this regard #t inconclusive and the great body of scientific evidence", "available", "the subject indicates that thc small amount", "carbon monoxide generated by cigarettes", "an insigni-", "ficant part of the total carbon monoxide", "the atmosphere", "L", "#4#" ]	[ [ 116, 98, 659, 399 ], [ 119, 409, 221, 423 ], [ 251, 409, 555, 427 ], [ 116, 434, 279, 452 ], [ 311, 437, 437, 453 ], [ 167, 477, 247, 493 ], [ 492, 477, 605, 497 ], [ 267, 479, 463, 495 ], [ 119, 507, 581, 523 ], [ 117, 533, 589, 551 ], [ 117, 561, 337, 579 ], [ 359, 561, 513, 579 ], [ 543, 563, 589, 577 ], [ 117, 588, 605, 607 ], [ 117, 617, 579, 661 ], [ 117, 671, 195, 687 ], [ 227, 671, 587, 689 ], [ 141, 700, 471, 717 ], [ 501, 701, 595, 717 ], [ 117, 727, 453, 745 ], [ 485, 729, 605, 745 ], [ 625, 751, 645, 839 ], [ 323, 785, 361, 799 ] ]	9
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1,000	772	letter	[ "Juno 11, 1970", "Harrlo", "BouLande", "Edltor", "pnerIcan ModIcal_Note", "535 North_Dearbera 54588t", "chiccgo.IllinoLe 60610", "Doar Harv}", "I bave folloved Ulth Euch Anterodt Yar_Focdet", "Aeboctatkon", "bacaudo", "AnarIcan Mur8ob", "art1c10b0n", "Cho", "tb0 NationaL Aeboctation for Proctical", "ef & c2lont.", "1ur80 Educaiton and Borvico (NAFHES) .", "epparent", "Intent", "attItodo and", "Df Eho", "Lank", "ewaro", "o[fIckal tovard 1Icenaod", "beadquartere", "cortaln", "AA", "tbe Board O[ DLrectord Q5 Faeics", "practIcal Dur94", "Iau Dontbe 480.", "e101ficunt", "statedodl", "adoptad", "Copy OI 4t", "{or joua", "a0 enclouing", "often", "and dlroctor\" OI Lartcs bavo", "Tbo offIcere", "Yondorod Luy certata AXA] Pooplo bate sOch", "Ebort -", "Dochted Atditude cancerasns Ticonaee praceicel 7t8ed", "Jerione bbertate Of boeb EZle", "thare", "mou", "44", "denyAng", "country:} Tboro I% DP", "end LPNa", "tbroughout tha", "urgentpoed and placo", "[or", "thero Lo", "tho", "[act", "that", "tenr", "Ebe baltb", "caro", "Doeb", "Bon-proflt_oreantratton that #", "FII,", "HAPKE8 10", "Cracticatod peorta", "dovotad antArely t0 tho {leld %f", "5any dodieatod", "ercan-eatton", "6ta", "'49is", "10'0", "{Lno", "coreditlng carvLco", "1ty eotabL Lahod", "Eba {Lrat", "tbat 10 today OITL -", "059838:*04t368", "mureLng", "Tor", "an5;ececo51", "o5 Educatlon.", "Focoealeod Dy_tho", "tbe NMA Eootlng Loter", "thLo", "t0 200 Jou dt", "I bopo", "bontb: Noenrh4lo; Dobt regardo:", "BLnceroly,", "zhn", "Loonard &'", "LszAe", "Enc)", "Mro . 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Lank ewaro Df Eho attItodo and epparent Intent cortaln AA beadquartere o[fIckal tovard 1Icenaod practIcal Dur94 tbe Board O[ DLrectord Q5 Faeics adoptad e101ficunt statedodl Iau Dontbe 480. a0 enclouing Copy OI 4t {or joua Tbo offIcere and dlroctor\" OI Lartcs bavo often Yondorod Luy certata AXA] Pooplo bate sOch Ebort - Dochted Atditude cancerasns Ticonaee praceicel 7t8ed 44 mou thare Jerione bbertate Of boeb EZle end LPNa tbroughout tha country:} Tboro I% DP denyAng tho [act that thero Lo urgentpoed and placo [or Doeb Ebe baltb caro tenr FII, HAPKE8 10 Bon-proflt_oreantratton that # dovotad antArely t0 tho {leld %f Cracticatod peorta 10'0 {Lno ercan-eatton 6ta 5any dodieatod '49is 1ty eotabL Lahod Eba {Lrat coreditlng carvLco Tor mureLng tbat 10 today OITL - an5;ececo51 059838:*04t368 Focoealeod Dy_tho o5 Educatlon. I bopo t0 200 Jou dt tbe NMA Eootlng Loter thLo bontb: Noenrh4lo; Dobt regardo: BLnceroly,", "Loonard &' zhn", "LszAe Enc) bcc $ Mro . 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762	1,000	memo	[ "septenber", "17,", "1988", "MEMORANDUM", "TO", "FILE:", "The", "following", "are", "my", "comments", "and", "observations", "comparing", "The", "Anerican", "Tobacco", "Company", "to", "the", "Liggett", "Group.", "in", "the", "last", "year", "and", "one-half,", "The", "American", "Tobacco", "Company", "has", "made", "extraordinary", "strides", "forward", "that", "strengthenea", "its", "prospects", "for", "continuing", "its", "long", "record", "of", "increasing", "profits", "-", ".", "the", "sales", "trend", "has", "significantiy", "improved,", "with", "the", "first", "half", "of", "1988", "showing", "an", "increase", "in", "units", "and", ".", "the", "marketing", "and", "sales", "organizations", "have", "been", "increased", "and", "strengthened", "(particularly", "important", "with", "the", "increased", "in-store", "activity", "required", "due", "to", "greater", "competitive", "price", "and", "promotional", "activities)", ".", "export", "units", "have" ]	[ [ 444, 167, 522, 179 ], [ 532, 167, 554, 179 ], [ 566, 167, 599, 177 ], [ 85, 280, 171, 289 ], [ 180, 280, 196, 289 ], [ 206, 280, 244, 289 ], [ 85, 307, 110, 317 ], [ 121, 307, 196, 319 ], [ 206, 309, 230, 317 ], [ 238, 309, 255, 319 ], [ 265, 308, 332, 317 ], [ 342, 307, 367, 317 ], [ 377, 306, 479, 317 ], [ 489, 307, 566, 319 ], [ 576, 307, 601, 317 ], [ 85, 321, 154, 331 ], [ 163, 321, 222, 331 ], [ 231, 322, 290, 334 ], [ 299, 322, 316, 331 ], [ 324, 321, 350, 331 ], [ 359, 320, 419, 333 ], [ 428, 322, 477, 333 ], [ 87, 407, 103, 415 ], [ 112, 406, 137, 415 ], [ 148, 406, 180, 415 ], [ 189, 408, 222, 418 ], [ 232, 406, 256, 415 ], [ 266, 406, 340, 417 ], [ 351, 406, 376, 415 ], [ 386, 405, 455, 415 ], [ 464, 406, 524, 415 ], [ 534, 406, 594, 418 ], [ 86, 420, 110, 429 ], [ 120, 420, 154, 429 ], [ 164, 419, 274, 432 ], [ 283, 419, 342, 429 ], [ 352, 420, 411, 429 ], [ 421, 420, 454, 429 ], [ 464, 420, 568, 432 ], [ 578, 419, 602, 429 ], [ 86, 434, 163, 446 ], [ 173, 434, 197, 443 ], [ 207, 433, 291, 446 ], [ 301, 433, 324, 443 ], [ 335, 434, 368, 446 ], [ 378, 434, 429, 443 ], [ 438, 434, 455, 443 ], [ 465, 433, 550, 446 ], [ 86, 447, 145, 460 ], [ 156, 452, 163, 454 ], [ 89, 483, 91, 485 ], [ 121, 476, 146, 485 ], [ 156, 476, 197, 485 ], [ 207, 476, 248, 485 ], [ 257, 476, 282, 485 ], [ 292, 475, 403, 488 ], [ 413, 476, 487, 488 ], [ 499, 476, 533, 485 ], [ 543, 476, 568, 485 ], [ 122, 489, 163, 499 ], [ 173, 490, 205, 499 ], [ 215, 490, 230, 499 ], [ 241, 490, 272, 500 ], [ 284, 490, 343, 502 ], [ 352, 492, 368, 499 ], [ 378, 492, 446, 499 ], [ 457, 492, 472, 499 ], [ 481, 490, 524, 499 ], [ 535, 490, 559, 499 ], [ 89, 538, 91, 541 ], [ 121, 531, 146, 541 ], [ 156, 531, 231, 544 ], [ 241, 531, 265, 541 ], [ 275, 531, 316, 541 ], [ 327, 531, 437, 543 ], [ 447, 531, 481, 541 ], [ 490, 531, 525, 541 ], [ 122, 545, 197, 555 ], [ 207, 545, 231, 555 ], [ 241, 545, 342, 557 ], [ 355, 545, 464, 557 ], [ 474, 545, 551, 557 ], [ 560, 545, 595, 555 ], [ 121, 559, 146, 569 ], [ 157, 559, 231, 569 ], [ 241, 559, 308, 569 ], [ 319, 560, 386, 571 ], [ 396, 559, 464, 571 ], [ 473, 559, 498, 569 ], [ 508, 560, 524, 569 ], [ 535, 560, 593, 571 ], [ 121, 573, 214, 585 ], [ 223, 573, 265, 585 ], [ 275, 574, 300, 583 ], [ 309, 573, 400, 585 ], [ 413, 573, 504, 585 ], [ 88, 608, 91, 611 ], [ 121, 602, 171, 613 ], [ 181, 601, 222, 611 ], [ 231, 602, 265, 611 ] ]	[ "septenber 17, 1988 MEMORANDUM TO FILE: The following are my comments and observations comparing The Anerican Tobacco Company to the Liggett Group. in the last year and one-half, The American Tobacco Company has made extraordinary strides forward that strengthenea its prospects for continuing its long record of increasing profits - . the sales trend has significantiy improved, with the first half of 1988 showing an increase in units and . the marketing and sales organizations have been increased and strengthened (particularly important with the increased in-store activity required due to greater competitive price and promotional activities) . export units have moved well above the 1 billion annual ea Durham factory was closed with a major reduction in very successful new products have been launched: BALL MALE Rel Filters and LIGHTS" ]	[ [ 85, 167, 602, 710 ] ]	15
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MUNTHLY MANACEMCNT Migration Of Nicotine (MIGON PROJECT TITLE: DATE : 7/30/78 DUDGET 829 615 FROJECT DESCRIPTION: Vrinci) Taicel (act YC\" Tlc J\"gima onirclyC Uis OEOiCCt rulti Wucl Oeliiui /0 WMAlio\" AIROt' Lrom Hd VaF[ [IA Iralaeto 7i\"\" 7tmts otht Weci nrA W Ei\" Wl\"\" T Sdi I! Vni# CIl # MAALION Mlc weiv \"MHcF Jls. L (1in4\" Jed# 104nIn, FLc . Yili alue Tivi ML4IAT claczel# lcvecu Tnch L7,in @Gn Hlia Jid rumuclc dcLCrMine ({uai uer cxtnjclnm UOli Tuct\"cniyc Wicidi] Lt(Cl delerinfic MUttc OLa(JCLUrfM Jfter lolccu ercollicut", "YEARAZL78 MONTH", "1", "30", "24", "1 W", "PROJECT COM PONEnts Huran", "Euyi", "neteniLC IIC\| Q1 ciu< MAiul OMLIEL", "Tal", "Jlcuei tnr Ael Cu Lrans [7t", "1,100 Total Hrs Budgeted", "758", "Date", "826 Hrs", "has been written on two experimental RL made Larson usinc A report lamina and stem: lamina ratio of 55:45 Smoking nicotine results ttgh taste panel results and leaf analyses the blend are included preference was noted for the experimental RL 70 8 available nicotine migrated filter paper treated with citric Up acid from filter paper treated with nicotine alkaloid: Tartaric acid produced migration nicotine alkaloid the acid treated paper No stoicometric relationship is readily apparent with these and other additives LAlmina Sue Ireland Sosnarn" ]	[ [ 689, 15, 737, 29 ], [ 56, 18, 725, 198 ], [ 173, 239, 263, 277 ], [ 73, 365, 85, 417 ], [ 195, 415, 217, 433 ], [ 195, 443, 217, 463 ], [ 73, 451, 175, 547 ], [ 77, 593, 219, 624 ], [ 178, 648, 208, 656 ], [ 78, 650, 168, 678 ], [ 192, 710, 214, 718 ], [ 80, 714, 183, 731 ], [ 271, 765, 501, 787 ], [ 527, 765, 555, 781 ], [ 207, 771, 247, 785 ], [ 97, 773, 165, 787 ], [ 97, 795, 773, 986 ] ]	10
1,000	754	file folder	[ "8", "1" ]	[ [ 705, 193, 719, 229 ], [ 581, 707, 601, 803 ] ]	[ "8", "1" ]	[ [ 705, 193, 719, 229 ], [ 581, 707, 601, 803 ] ]	8
754	1,000	news article	[ "5", "2", "MT", "ion", "2", "House", "Democrats", "Offer", "a", "Compromise", "on", "Tobacco", "Regulati", "‘By", "PHILIP", "ta", "na", "agency", "denn", "tout:", "vo", "‘me", "Rosse", "props", "er", "Jay", "26", "—", "Two", "on", "OM", "nas", "wing", "1", "cis", "Tr", "eld", "pA", "EDA", "equi", "Cr", "DA", "are", "tes", "ne", "eu", "fom", "ee", "fn", "ceguaton", "of", "tobaceo,", ">", "have", "enaless", "ag", "nat”", "sd", "ote", "Peel", "ee", "08", "ves", "ecto", "la", "ere", "ie", "dca", "rei:", "go", "wig", "eae", "at", "ton", "weld", "en", "terror", "Tay", "nner", "ent", "tBu", "en", "ta", "ine", "Sent", "materi", "tis", "month,", "the", "agency", "as-", "Food", "and", "Drea,", "asserted", "‘One", "guaranice", "in", "thd", "proposal" ]	[ [ 550, 89, 560, 95 ], [ 615, 85, 630, 93 ], [ 471, 90, 517, 113 ], [ 675, 158, 701, 170 ], [ 30, 161, 44, 179 ], [ 49, 159, 115, 179 ], [ 120, 159, 233, 180 ], [ 241, 159, 295, 180 ], [ 300, 167, 313, 180 ], [ 320, 159, 449, 185 ], [ 456, 165, 481, 178 ], [ 490, 155, 579, 176 ], [ 584, 151, 675, 177 ], [ 57, 184, 76, 212 ], [ 81, 184, 114, 212 ], [ 205, 183, 212, 218 ], [ 237, 197, 252, 214 ], [ 256, 196, 304, 214 ], [ 308, 196, 331, 206 ], [ 335, 197, 367, 206 ], [ 178, 191, 196, 226 ], [ 398, 211, 415, 218 ], [ 419, 208, 545, 219 ], [ 475, 192, 505, 228 ], [ 514, 192, 547, 228 ], [ 118, 213, 137, 222 ], [ 143, 213, 152, 220 ], [ 156, 195, 163, 230 ], [ 174, 213, 194, 220 ], [ 151, 213, 160, 246 ], [ 176, 213, 193, 246 ], [ 245, 213, 262, 246 ], [ 267, 218, 349, 238 ], [ 297, 213, 309, 246 ], [ 354, 229, 370, 236 ], [ 536, 218, 549, 237 ], [ 389, 232, 415, 251 ], [ 420, 221, 429, 257 ], [ 426, 231, 484, 251 ], [ 490, 230, 549, 249 ], [ 531, 221, 549, 257 ], [ 301, 227, 319, 262 ], [ 277, 250, 329, 268 ], [ 336, 250, 370, 268 ], [ 390, 256, 401, 262 ], [ 423, 253, 454, 273 ], [ 453, 237, 479, 277 ], [ 483, 252, 550, 270 ], [ 31, 267, 48, 274 ], [ 52, 266, 146, 276 ], [ 99, 253, 108, 284 ], [ 109, 266, 146, 276 ], [ 197, 271, 204, 276 ], [ 262, 273, 272, 278 ], [ 294, 273, 307, 279 ], [ 137, 277, 170, 284 ], [ 175, 277, 193, 284 ], [ 365, 271, 370, 279 ], [ 526, 257, 550, 295 ], [ 218, 292, 273, 302 ], [ 328, 293, 370, 301 ], [ 534, 270, 552, 306 ], [ 297, 280, 315, 316 ], [ 338, 305, 347, 311 ], [ 501, 280, 516, 316 ], [ 208, 314, 256, 321 ], [ 261, 316, 285, 322 ], [ 291, 315, 314, 322 ], [ 319, 305, 370, 322 ], [ 429, 291, 438, 327 ], [ 474, 306, 514, 313 ], [ 544, 314, 552, 322 ], [ 149, 320, 175, 327 ], [ 208, 326, 228, 332 ], [ 234, 325, 270, 334 ], [ 262, 301, 284, 338 ], [ 305, 325, 367, 333 ], [ 385, 301, 412, 338 ], [ 416, 317, 492, 330 ], [ 208, 335, 265, 343 ], [ 271, 336, 369, 343 ], [ 332, 312, 349, 351 ], [ 452, 312, 473, 351 ], [ 31, 327, 51, 363 ], [ 386, 329, 416, 364 ], [ 421, 340, 456, 347 ], [ 72, 339, 92, 369 ], [ 95, 339, 125, 369 ], [ 128, 339, 142, 369 ], [ 145, 339, 177, 369 ], [ 180, 339, 192, 369 ], [ 208, 357, 233, 364 ], [ 241, 358, 249, 364 ], [ 273, 353, 294, 365 ], [ 311, 359, 325, 365 ], [ 402, 355, 419, 363 ], [ 424, 353, 495, 364 ], [ 468, 341, 483, 370 ], [ 485, 341, 502, 370 ], [ 504, 352, 541, 362 ] ]	[ "5 2 MT ion 2 House Democrats Offer a Compromise on Tobacco Regulati ‘By PHILIP ta na agency denn tout: vo ‘me Rosse props er Jay 26 — Two on OM nas wing 1 cis Tr eld pA EDA equi Cr DA are tes ne eu fom ee fn ceguaton of tobaceo, > have enaless ag nat” sd ote Peel ee 08 ves ecto la ere ie dca rei: go wig eae at ton weld en terror Tay nner ent tBu en ta ine Sent materi tis month, the agency as- Food and Drea, asserted ‘One guaranice in thd proposal is an addictive drug and regu. Polilcally dangerous question of power if the som ute ty 4 Ne see arama ey North Carolina Democeat who has debate comes as une Justice. Chacon and every tO cue cave nat ae resentative Ron Wyden of Oregon’ Dany executives lied to Congress or —— — Ro, en of se remand 0 me une revises Ha waa ena ana ae oe etic more a yearto he Deprtment\| ew a 2h der chore re pring one lela sat from adverusing in e way intended} that the. was doce. iets \| wat are ary oy st ye ested FT al a Re fear thatthe tobacco companies wil \| could use the treat of sch ‘Wyden sad today that he \| rake concessions satay ett a \| iy\" ay \| wae om Fite tobacco, “That's what Keeps the \| Proposal the right thing in this proposal,” he \|. study by the White House, wi \| 6 2 by te tiated Set mang ‘Administration could avold nasty \| marketing of Het ver would be done to Rose said the tobacco industry \| ting che most effective messages many te] malorky in ina, single, am ‘here are licking their chops for that \| » ‘one. They want to go head-to-head Some elements of the campaign s ea Nonetheless, Mr. Rose said that} chines and improving enforcement g “while both sides might have trouble } Gf laws that bar sales to minors. It 8 ‘with his plan, it would be worthwhile } would also include educational cam- g i es mapa stow eat] le so, tt and the tobacco from adversing to be et" ]	[ [ 18, 85, 701, 898 ] ]	9
762	1,000	memo	[ "DEA", "THE", "Memorandum", "AMERICAN", "TOBACCO,", "COMPANY,", "we", "Mr.", "E.", "C.", "Wortham", "oye", "9/17/92", "tn", "Glock,", "Leaf", "services", "Nenager", "ond’", "purley", "strips", "~", "1992", "&", "1992", "erope", "of", "serine", "ko.", "6379", "grades", "ray", "nave", "Ene", "potential", "fer", "in", "ou", "™~", "ge", "0211872" ]	[ [ 569, 37, 617, 54 ], [ 190, 63, 220, 74 ], [ 536, 63, 622, 74 ], [ 191, 76, 266, 88 ], [ 190, 88, 259, 99 ], [ 190, 102, 262, 112 ], [ 138, 153, 143, 173 ], [ 190, 159, 210, 167 ], [ 222, 159, 234, 167 ], [ 244, 159, 256, 167 ], [ 267, 159, 321, 168 ], [ 535, 155, 549, 176 ], [ 585, 160, 637, 171 ], [ 138, 196, 152, 201 ], [ 244, 197, 287, 207 ], [ 299, 197, 328, 206 ], [ 337, 197, 397, 206 ], [ 406, 198, 460, 208 ], [ 260, 209, 282, 218 ], [ 244, 235, 290, 246 ], [ 299, 234, 343, 246 ], [ 352, 239, 359, 241 ], [ 369, 236, 397, 244 ], [ 407, 236, 413, 244 ], [ 423, 236, 451, 244 ], [ 461, 236, 498, 246 ], [ 222, 323, 236, 331 ], [ 244, 323, 290, 334 ], [ 608, 325, 628, 333 ], [ 639, 325, 668, 334 ], [ 159, 374, 204, 385 ], [ 213, 376, 235, 385 ], [ 244, 375, 274, 383 ], [ 283, 375, 305, 383 ], [ 314, 375, 381, 385 ], [ 392, 375, 413, 383 ], [ 454, 374, 467, 384 ], [ 476, 377, 498, 384 ], [ 458, 420, 476, 431 ], [ 275, 578, 313, 589 ], [ 563, 860, 620, 871 ] ]	[ "DEA THE Memorandum AMERICAN TOBACCO, COMPANY, we Mr. E. C. Wortham oye 9/17/92 tn Glock, Leaf services Nenager ond’ purley strips ~ 1992 & 1992 erope of serine ko. 6379 grades ray nave Ene potential fer in ou ™~ ge 0211872" ]	[ [ 138, 37, 668, 871 ] ]	15
754	1,000	email	[ "From:", "Cole,", "Ron", "W.", "To:", "Ainsworth,", "W.E.", "(Gene);", "Alan", "Calhoun;", "Anne", "Miller;", "Barbara", "Goho;", "Beverly", "Paszkowski;", "Brenda", "Matthews;", "Bryan", "Snipes;", "Carole", "Crosslin;", "Carolyn", "Brinkley;", "‘Christopher", "Garland;", "Darryl", "Marsch;", "David", "Howard;", "David", "Powers;", "Delise", "LeBlanc;", "Denise", "Santos;", "Dianne", "Neal;", "Donald", "Foreman;", "Ellen", "Merritt;", "Frank", "Lester;", "Frank", "Skinner;", "Geni", "Coulter;", "Glenda", "Evans;", "Glenda", "Goodman;", "Guy", "Blynn;", "H.", "Bert", "Gomez;", "Harvey", "Freeman;", "Henry", "Stokes;", "Jackie", "Hemric;", "Jan", "Fulton", "Smith:", "Jean", "Lowstetter;", "Jerry", "MacFarland;", "Joan", "Rutledge;", "Joc", "Murray;", "John", "Fish;", "John", "Singleton;", "Joseph", "Coffey;", "Joyce", "Muench;", "Judy", "Albert;", "Judy", "Dobbs;", "Karen", "Baker;", "Keith", "Kolischak;", "Kevin", "Richardson;", "Lynn", "Hutchens;", "M.", "Hurst", "Marshall;", "Mary", "Hampton;", "Maura" ]	[ [ 112, 86, 150, 97 ], [ 154, 86, 184, 99 ], [ 189, 86, 211, 97 ], [ 216, 87, 229, 97 ], [ 112, 103, 132, 115 ], [ 137, 104, 200, 116 ], [ 205, 104, 233, 115 ], [ 238, 104, 280, 117 ], [ 285, 105, 311, 116 ], [ 315, 105, 367, 117 ], [ 372, 105, 402, 116 ], [ 407, 106, 445, 118 ], [ 450, 106, 494, 117 ], [ 498, 106, 532, 119 ], [ 532, 103, 581, 125 ], [ 112, 121, 183, 134 ], [ 188, 121, 228, 133 ], [ 232, 122, 291, 134 ], [ 296, 122, 329, 137 ], [ 334, 122, 375, 137 ], [ 379, 123, 417, 134 ], [ 421, 123, 472, 136 ], [ 476, 123, 520, 138 ], [ 516, 120, 577, 143 ], [ 112, 139, 179, 153 ], [ 183, 140, 232, 152 ], [ 237, 140, 272, 153 ], [ 277, 140, 322, 152 ], [ 328, 140, 361, 151 ], [ 366, 141, 415, 153 ], [ 420, 141, 453, 152 ], [ 458, 141, 502, 153 ], [ 507, 142, 543, 153 ], [ 547, 142, 597, 154 ], [ 112, 156, 151, 167 ], [ 156, 156, 196, 168 ], [ 201, 157, 241, 168 ], [ 246, 157, 275, 169 ], [ 280, 157, 321, 168 ], [ 326, 157, 379, 170 ], [ 384, 158, 413, 169 ], [ 418, 158, 461, 170 ], [ 466, 158, 498, 169 ], [ 502, 159, 540, 171 ], [ 545, 159, 577, 170 ], [ 112, 174, 159, 186 ], [ 164, 174, 191, 185 ], [ 195, 174, 241, 186 ], [ 246, 174, 286, 186 ], [ 291, 175, 328, 187 ], [ 333, 175, 374, 186 ], [ 378, 175, 437, 188 ], [ 442, 176, 465, 190 ], [ 470, 176, 506, 190 ], [ 511, 177, 520, 187 ], [ 529, 177, 552, 188 ], [ 556, 177, 600, 189 ], [ 113, 192, 153, 205 ], [ 158, 191, 210, 203 ], [ 214, 192, 249, 205 ], [ 253, 192, 294, 204 ], [ 298, 192, 334, 203 ], [ 338, 192, 384, 205 ], [ 389, 193, 407, 204 ], [ 412, 193, 447, 204 ], [ 452, 193, 489, 205 ], [ 494, 194, 518, 205 ], [ 523, 194, 586, 207 ], [ 590, 195, 618, 209 ], [ 112, 209, 184, 221 ], [ 188, 209, 214, 220 ], [ 219, 209, 272, 223 ], [ 277, 210, 295, 221 ], [ 300, 210, 345, 224 ], [ 349, 210, 376, 221 ], [ 381, 211, 408, 223 ], [ 412, 211, 439, 222 ], [ 444, 211, 500, 225 ], [ 505, 212, 543, 226 ], [ 547, 212, 589, 226 ], [ 112, 226, 144, 239 ], [ 148, 226, 197, 238 ], [ 202, 227, 228, 240 ], [ 233, 227, 271, 238 ], [ 276, 227, 301, 240 ], [ 307, 227, 347, 239 ], [ 352, 228, 385, 238 ], [ 390, 228, 427, 239 ], [ 432, 228, 462, 239 ], [ 467, 229, 527, 241 ], [ 532, 229, 565, 240 ], [ 113, 243, 180, 254 ], [ 184, 244, 213, 257 ], [ 218, 244, 274, 255 ], [ 278, 244, 294, 255 ], [ 299, 244, 330, 255 ], [ 334, 244, 388, 257 ], [ 393, 245, 421, 259 ], [ 426, 245, 482, 259 ], [ 487, 246, 523, 257 ] ]	[ "From: Cole, Ron W. To: Ainsworth, W.E. (Gene); Alan Calhoun; Anne Miller; Barbara Goho; Beverly Paszkowski; Brenda Matthews; Bryan Snipes; Carole Crosslin; Carolyn Brinkley; ‘Christopher Garland; Darryl Marsch; David Howard; David Powers; Delise LeBlanc; Denise Santos; Dianne Neal; Donald Foreman; Ellen Merritt; Frank Lester; Frank Skinner; Geni Coulter; Glenda Evans; Glenda Goodman; Guy Blynn; H. Bert Gomez; Harvey Freeman; Henry Stokes; Jackie Hemric; Jan Fulton Smith: Jean Lowstetter; Jerry MacFarland; Joan Rutledge; Joc Murray; John Fish; John Singleton; Joseph Coffey; Joyce Muench; Judy Albert; Judy Dobbs; Karen Baker; Keith Kolischak; Kevin Richardson; Lynn Hutchens; M. Hurst Marshall; Mary Hampton; Maura Payne; Michael Suggs; Mike Phillips; Murray Jones; Nelson, Byron (WKA); Patricia Lawrence; Patricia Mabe; Peter Schmidt; Phyllis Rumple; R. Keith; Randy Tompson; Richard Williams: Rogene Smith; Roger Mozingo; Seth Moskowitz; Sharon Reid; Sheryl Spainhour; Shirley Miller; Steve Strawsburg; Teresa Wood; Timothy Fields; Timothy Swoope; Tommy Payne; Vickie Parrish; Vicky Pierce; Vivian Tumer; William Cook cc: BCC; Primary Date: 12/3/1999 11:25:31 AM Last Modified Date: 1999-Dec-03 11:25:33 Last Touched Date: Sent Date: 1999-Dec-03 11:25:31 Received Date: 1999-Dec-03 11:25:31 Subject: State Government Relations Weekly Status - 12/02/99 Attachments: SGRw991202.DOC 8 8 & & 2 RJR0000001531090253 ° 70029 3568" ]	[ [ 0, 86, 706, 981 ] ]	2
754	1,000	resume	[ "PRINCIPLE", "INVESTIGATOR:", "Reuben", "Eisenstein,", "M.D.", "Date", "of", "Birth:", "May", "3,", "1929", "EDUGATION:", "Tulane", "University,", "B.S.,", "1949,", "Biology", "State", "University,", "M.D.,", "1953,", "Medicine", "Me,", "Sinai", "Hospital,", "New", "York,", "1954,", "Intera", "Presbyterian-St.", "Luke's", "Hospital,", "Chicago,", "1957-60,", "Pathology", "Resident", "Professional", "Experience:", "Assistant", "Attending", "to", "Attending", "Pathologist,", "Presbyterian-St.", "Hospital,", "Chicago,", "IL,", "1960-75;", "Assistant", "Professor", "to", "Professor", "of", "Pathology,", "University", "of", "Iilinois", "Medical", "School,", "1960-69;", "Professor", "of", "Pathology,", "Rush", "Medical", "Colles", "1971-73;", "Dizeczor", "of", "Cytopathology,", "and", "Surgical", "Pathology,", "Presbyterian~St.", "Luke's", "Hospita", "1965-70;", "Dizector", "of", "Special", "Pathology,", "Luke's", "Hospital,", "1970-75;", "Professe", "of", "Pathology,", "Northwestern.", "University-Medical", "School,", "1975-80;", "arcending", "Pathologist,", "Menorial", "Hospital,", "1975-80;", "Director", "of", "Chemistry,", "Immunology," ]	[ [ 105, 53, 169, 62 ], [ 178, 52, 269, 62 ], [ 286, 52, 329, 62 ], [ 337, 52, 415, 63 ], [ 424, 52, 451, 62 ], [ 104, 69, 133, 78 ], [ 141, 68, 155, 78 ], [ 162, 68, 204, 78 ], [ 221, 69, 242, 80 ], [ 251, 68, 263, 79 ], [ 272, 68, 301, 78 ], [ 105, 98, 175, 108 ], [ 105, 120, 148, 130 ], [ 156, 121, 234, 132 ], [ 242, 121, 277, 131 ], [ 287, 120, 321, 131 ], [ 329, 120, 380, 132 ], [ 178, 137, 213, 145 ], [ 221, 136, 299, 147 ], [ 307, 136, 343, 146 ], [ 352, 136, 386, 146 ], [ 395, 136, 453, 145 ], [ 105, 151, 125, 160 ], [ 134, 151, 170, 160 ], [ 178, 151, 241, 162 ], [ 250, 151, 272, 160 ], [ 279, 151, 314, 161 ], [ 323, 150, 357, 161 ], [ 367, 151, 409, 160 ], [ 105, 166, 219, 177 ], [ 228, 165, 271, 175 ], [ 279, 166, 343, 177 ], [ 352, 166, 409, 177 ], [ 418, 165, 474, 176 ], [ 482, 166, 548, 177 ], [ 555, 166, 613, 175 ], [ 21, 312, 117, 323 ], [ 124, 312, 210, 322 ], [ 226, 310, 298, 321 ], [ 305, 309, 377, 321 ], [ 386, 310, 400, 319 ], [ 408, 307, 479, 319 ], [ 486, 305, 578, 318 ], [ 587, 305, 709, 318 ], [ 77, 324, 147, 342 ], [ 157, 328, 218, 341 ], [ 227, 327, 250, 339 ], [ 259, 326, 321, 339 ], [ 330, 326, 401, 338 ], [ 408, 324, 478, 335 ], [ 487, 325, 502, 333 ], [ 510, 322, 580, 333 ], [ 588, 321, 603, 332 ], [ 610, 321, 687, 335 ], [ 21, 346, 101, 358 ], [ 109, 345, 124, 356 ], [ 133, 345, 196, 356 ], [ 203, 343, 259, 354 ], [ 267, 342, 321, 355 ], [ 330, 340, 391, 354 ], [ 401, 340, 471, 352 ], [ 479, 338, 494, 349 ], [ 502, 338, 579, 351 ], [ 588, 337, 619, 348 ], [ 625, 337, 681, 348 ], [ 689, 337, 735, 350 ], [ 22, 362, 83, 375 ], [ 92, 362, 156, 373 ], [ 165, 361, 179, 372 ], [ 189, 359, 298, 374 ], [ 306, 358, 330, 369 ], [ 338, 357, 401, 372 ], [ 408, 356, 485, 369 ], [ 493, 354, 618, 368 ], [ 626, 353, 672, 365 ], [ 680, 354, 735, 367 ], [ 22, 378, 82, 391 ], [ 92, 378, 157, 389 ], [ 165, 377, 179, 388 ], [ 188, 375, 243, 390 ], [ 242, 364, 329, 395 ], [ 471, 370, 517, 383 ], [ 524, 370, 595, 383 ], [ 604, 369, 664, 383 ], [ 673, 370, 735, 380 ], [ 22, 394, 37, 406 ], [ 44, 394, 123, 408 ], [ 131, 381, 232, 412 ], [ 235, 381, 378, 412 ], [ 386, 389, 438, 402 ], [ 448, 388, 509, 401 ], [ 517, 387, 589, 400 ], [ 596, 386, 688, 400 ], [ 123, 409, 188, 421 ], [ 196, 408, 265, 422 ], [ 275, 407, 337, 420 ], [ 345, 407, 408, 418 ], [ 417, 405, 432, 416 ], [ 440, 404, 517, 417 ], [ 526, 402, 611, 415 ] ]	[ "PRINCIPLE INVESTIGATOR: Reuben Eisenstein, M.D. Date of Birth: May 3, 1929 EDUGATION: Tulane University, B.S., 1949, Biology State University, M.D., 1953, Medicine Me, Sinai Hospital, New York, 1954, Intera Presbyterian-St. Luke's Hospital, Chicago, 1957-60, Pathology Resident Professional Experience: Assistant Attending to Attending Pathologist, Presbyterian-St. Hospital, Chicago, IL, 1960-75; Assistant Professor to Professor of Pathology, University of Iilinois Medical School, 1960-69; Professor of Pathology, Rush Medical Colles 1971-73; Dizeczor of Cytopathology, and Surgical Pathology, Presbyterian~St. Luke's Hospita 1965-70; Dizector of Special Pathology, Luke's Hospital, 1970-75; Professe of Pathology, Northwestern. University-Medical School, 1975-80; arcending Pathologist, Menorial Hospital, 1975-80; Director of Chemistry, Immunology, and Serology, Worthvestern Hospital, 1975-76; Director of Leboratories, VA Lakeside Hospizal, 1576-80; Chief, of Pathology and Laboratory Medicine, Mount Sinai Medical Center and Departnent of Pathology, University of 1980-present. Board of Pathology (Anatomic 1959; Clinical 1964). ere.: Menber, B. Stuéy Section, 1967-71; Consul~ fst, Procter and Company, 1973-751 Ad Hoc NELI, 1975, 1979; Medical Advisory Board, Leukenta Foundation, Inc., 1978-present; Editorial Board, Arterdosclerosis, 1980-present; Visiting Professor, several universities, 1965-present. 94 + : B., ayer, Papjiannis, S., Hess, and Ellis, H.: Mineral bindin; by arterial elastic tissue. Lab. Invest., 13:1198, 1964. : 2. E., Eisenstein, R., Sky-Peck, and HéDonald, J.B.: Electron microscopy \" tritiated thymidine in graduation of malignancy of human bladder carcinomas. Te. Am, Assoc. 56:31, 1964, 3. Eisenstein, R., Rosato, J. and Wied, G.: DNA and protein in hypertrophi: human hearts. Proc. Soc. Exp. Biol. Med., 1332176, 1970. 4. Eisenstein, R-, Soble, and Kuettner, K.E.: Lysozyme in epiphyseal cartilage. TI. The effects of on mouse enbryonic cartilage in organ culture. An. J. Path., 60:43, 1970. Eisenstein, R., Arsenis, C. and Kuettner, K.: Electron microscopic studies of carti— Jage matrix using lysozyme as a vital stain. J. Cell Biol.» 46626, 1970. 6. Eisenstein, BR.» Scott, R.A. end Lesak, A.: Altered Lipid binding by mineralized elastin. Arch. Path,, 92:301, 1971. 7. Eisenstein, R., Sorgente, N. and Kuettner, K.E.: Organization of extra-cellular natr of epiphyseal growth plate. Aner. J. Path., 65:515, 1972. 8, Eisenstein, Re, S., Sorgente, N. and Kuettner, K.E.: Collegen-proteoglycan relationships in epiphyseal cartilage. Am. J. 732443, 1973. 3 Eisenstein, R., Sorgente, N., Soble, L., Miller, A, and Kuettner, The resis~ tance of certain tissues to An. J. Path., 73:765, 1973. NO. Sorgence, N., Kuettner, K.E-, Soble, LW. and Eisenstein, The of tain tissues to invasion. Ii. Evidence for extractable factors in cartilage which davasion by vasewlarized nasenchyne. Lab. Invest., 32:217, 1975. 50186844" ]	[ [ 16, 52, 735, 997 ] ]	14
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777	1,000	presentation	[ "¥)30", "JOHN", "MURPHY", "CLOSING", "REMARKS", "PHILIP", "MORRIS'S", "GROWTH", "OVER", "THE", "PAST", "SEVERAL", "YEARS", "IS", "WELL", "KNOWN.", "WE", "HAVE", "NOT", "GOTTEN", "WERE", "WE", "ARE", "TODAY", "BY", "BEING", "COMPLACENT,", "BUT", "RATHER", "BY", "STRIVING", "TO", "BE", "BEST", "AT", "WHAT", "WE", "KNOW", "BEST.", "YOU'VE", "HEARD", "QUITE", "A", "BIT", "ABOUT", "OUR", "BUSINESSES", "HERE", "TODAY.", "LET", "ME", "COMMENT", "ON", "SOME", "OF", "THE", "UNDERLYING", "TRENDS", "AND", "SUMMARIZE", "OUR", "CURRENT", "POSITION.", "FIRST", "LET'S", "TAKE", "A", "LOOK", "AT", "THE", "U.S.", "CIGARETTE", "INDUSTRY.", "RECENT", "VOLUME", "GROWTH", "HAS", "BEEN", "LACKING.", "WE", "ARE", "ALSO", "CONCERNED", "WITH", "THE", "6URDEN", "OF", "EXCISE", "TAXES,", "MARKETING", "RESTRICTIONS,", "RESTRICTIONS", "ON", "SMOKING,", "THE", "SMOKING", "AND", "HEALTH", "CONTROVERSY", "AND" ]	[ [ 645, 83, 683, 99 ], [ 304, 137, 337, 147 ], [ 347, 136, 398, 147 ], [ 287, 167, 345, 177 ], [ 356, 167, 415, 177 ], [ 209, 225, 259, 235 ], [ 269, 224, 336, 235 ], [ 346, 225, 398, 235 ], [ 408, 225, 441, 235 ], [ 451, 225, 475, 235 ], [ 485, 225, 518, 236 ], [ 148, 254, 207, 264 ], [ 218, 254, 259, 264 ], [ 270, 254, 284, 264 ], [ 294, 255, 328, 264 ], [ 338, 255, 387, 265 ], [ 408, 255, 424, 265 ], [ 434, 256, 466, 265 ], [ 477, 256, 501, 266 ], [ 148, 283, 199, 293 ], [ 208, 283, 242, 293 ], [ 251, 283, 267, 293 ], [ 277, 283, 302, 293 ], [ 311, 283, 353, 293 ], [ 365, 284, 380, 293 ], [ 391, 283, 432, 293 ], [ 442, 284, 532, 296 ], [ 148, 311, 172, 321 ], [ 182, 312, 232, 321 ], [ 244, 312, 258, 321 ], [ 269, 312, 336, 322 ], [ 345, 312, 362, 322 ], [ 373, 312, 389, 322 ], [ 400, 312, 432, 323 ], [ 442, 312, 458, 322 ], [ 467, 313, 500, 323 ], [ 510, 313, 525, 323 ], [ 148, 342, 180, 352 ], [ 191, 342, 231, 352 ], [ 208, 400, 258, 411 ], [ 268, 401, 310, 411 ], [ 319, 401, 361, 414 ], [ 372, 402, 379, 411 ], [ 390, 401, 415, 411 ], [ 424, 402, 465, 412 ], [ 475, 402, 499, 412 ], [ 148, 429, 232, 439 ], [ 242, 429, 275, 439 ], [ 285, 430, 333, 440 ], [ 355, 430, 380, 440 ], [ 390, 430, 405, 440 ], [ 416, 430, 474, 440 ], [ 483, 431, 500, 441 ], [ 510, 431, 542, 441 ], [ 147, 458, 163, 468 ], [ 172, 458, 197, 468 ], [ 208, 458, 292, 468 ], [ 302, 458, 352, 468 ], [ 363, 459, 388, 468 ], [ 399, 459, 474, 469 ], [ 483, 460, 507, 469 ], [ 147, 487, 206, 497 ], [ 216, 487, 290, 498 ], [ 311, 488, 353, 498 ], [ 363, 487, 405, 498 ], [ 415, 488, 448, 498 ], [ 458, 489, 465, 498 ], [ 475, 489, 507, 499 ], [ 517, 490, 534, 499 ], [ 146, 517, 171, 527 ], [ 181, 517, 212, 527 ], [ 225, 517, 300, 527 ], [ 312, 517, 385, 527 ], [ 207, 575, 257, 585 ], [ 267, 575, 317, 585 ], [ 327, 575, 378, 585 ], [ 389, 575, 413, 585 ], [ 424, 576, 456, 585 ], [ 466, 576, 531, 586 ], [ 146, 603, 161, 613 ], [ 171, 603, 196, 613 ], [ 206, 603, 240, 613 ], [ 250, 604, 325, 613 ], [ 335, 604, 369, 614 ], [ 379, 604, 404, 614 ], [ 415, 605, 464, 614 ], [ 474, 605, 490, 614 ], [ 500, 605, 550, 615 ], [ 145, 632, 193, 643 ], [ 206, 632, 282, 642 ], [ 293, 632, 402, 644 ], [ 414, 633, 515, 644 ], [ 525, 634, 541, 644 ], [ 146, 661, 211, 672 ], [ 223, 661, 248, 671 ], [ 258, 661, 316, 671 ], [ 326, 661, 351, 671 ], [ 361, 662, 412, 671 ], [ 422, 662, 514, 672 ], [ 525, 663, 550, 672 ] ]	[ "¥)30 JOHN MURPHY CLOSING REMARKS PHILIP MORRIS'S GROWTH OVER THE PAST SEVERAL YEARS IS WELL KNOWN. WE HAVE NOT GOTTEN WERE WE ARE TODAY BY BEING COMPLACENT, BUT RATHER BY STRIVING TO BE BEST AT WHAT WE KNOW BEST. YOU'VE HEARD QUITE A BIT ABOUT OUR BUSINESSES HERE TODAY. LET ME COMMENT ON SOME OF THE UNDERLYING TRENDS AND SUMMARIZE OUR CURRENT POSITION. FIRST LET'S TAKE A LOOK AT THE U.S. CIGARETTE INDUSTRY. RECENT VOLUME GROWTH HAS BEEN LACKING. WE ARE ALSO CONCERNED WITH THE 6URDEN OF EXCISE TAXES, MARKETING RESTRICTIONS, RESTRICTIONS ON SMOKING, THE SMOKING AND HEALTH CONTROVERSY AND LITIGATION. x 3 x racy + 3" ]	[ [ 145, 83, 703, 855 ] ]	12
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1,000	772	scientific publication	[ "ol Min", "Jott4", "Au", "Md-Tkn", "Hnlur", "Aam", "Atrhin", "Analysis of the Hormone-dependent Regulation of a", "JunD)-Estrogen", "Receptor Chimcra", "pl liratiort", "Februaty", "Kovemlct", "1995/", "(Ccc1ol", "Trecd orm", "Kevin Ryden", "Xoy", "Mary", "Honald", "Fhinncys_", "Hnc", "Francisi", "Wilorda", "Elamo 9] /", "Kotuc Far", "Ccntct", "Ur", "AeMcnt", "unden\"", "nnd junl)", "elily", "Jor", "The moduler ligand-hinding donains of steruid reccp", "CUM", "8lmt,", "identical, regulation", "Cenc-Oa", "Ecncratemolein chimerne", "trat share", "high", "Iore ar", "rotcis", "been widely uAcd", "~identity (11. '\"hcy Ara also sitna", "tha", "ligund dependent for #clivily.In", "acid", "Finilat nilinie", "dcirc", "euttuIO", "Rpnuchce", "with c-Fos and Fos-rclated proleins (2).", "conditionally", "thcir irteraction", "Hun)", "acl", "Uar", "Lcncrelcc", "Rcrice", "cnlvoxyl", "(( (OF)-", "IN at AF'] silcs", "u ut", "Jun Cox dimct", "comnicxcsmd", "by fusing", "mt", "Droldins", "tficI", "(OOA-terminal fragmett", "Jarminn", "PnCS . Sirco", "cnGE", "with", "Ad rckulia", "(tc' CutRRi0n", "LATE4", "arid", "ligund.", "thntt", "Juduced", "(EH)", "rapidly", "Juan", "conuins Uc", "Trogcn rcctmor", "amtily ncmticna", "n TcRuunso", "extrarciu", "binding domnin:", "(FKI cki:", "Junl)EJe (IKII) nud", "imnncdiate cark", "Foir", "lar Growth siunls", "tncy", "nic cinesuice", "zippcr", "Hiti", "iulec", "Lauci", "Inic", "TEun", "Kxpression", "IArX", "Lnce 0", "Hamilies is", "snonE(", "Ecnt&", "Eenc", "exhihit hornon", "ctivalion", "aclnttur", "urO", "inlcgrul parl of a well-orchcstraled cascadc", "leading t0", "~onenacn", "cvoras", "tcin-]-dirceted trnuecription in transicni exprcSsion MR -", "ceulat", "pralilcratior", "3nd", "Tclercnces", "unortiul", "Cci", "fusions, IKK , hae", "Ont", "AhteO", "no", "nramTICO", "GhIc", "the celluler Frowth", "HEMIAICLAML Darlicinus", "pruem", "Uacus", "dctnil", "decrmninc", "tucclaniem", "nction", "analyzing thc direrl checls", "furtoi", "Eludics", "hese", "resunnuro", "cxperimcnt:", "IT", "olfilittureonilion", "Wte", "Mrrane", "Ercatly", "mroleing 0I", "FCIIO", "crnressiol", "Truwtn", "wania", "dcmonstratc that", "Iromt HEK", "und Fos", "iranefccica", "cclls", "facilitaled by a wcll characlcrizcd inducible expression syslem.", "Cur", "Fos And IKI rendil,", "arneehntorutinicr", "omncxtR", "Onc #pproach for crcating", "inducible system", "lucuse :", "prisingly, the formntion", "Fos:II heterodimers;", "plucing te uctivity o", "protcin under", "Ihe control ofthc lieatd -", "IFI", "#osRInC", "Fnn] cclimcie", "troren-inarundcn,", "sleroid", "uding", "dumAI", "Wanlomo", "rectuior", "Ruch", "Howcvcr, Eel shift ASSAYR clcarly dcmonstrate that I)NA", "Elucocorlicoid receplor (GJ)", "AFI sitcs hy Fos:I)ER hctcrodimcrs", "(hc CstIOgch rereptor (KKA St -", "IKI", "hincing", "crealed wilh proteins", "hsimi", "urolems", "HaVC [icl", "homodimcra", "cAtrogon-dopondena.Mor Ovcr,", "Ihcal-", "FCI", "Such os FIA (4), c-Myc (54 the CCAATenhancer-binding", "un cflectivc inhil", "GcnCO", "cetroecn", "Inc nhi", "wrotcin", "(61, Myol) (7), 053 (8L, and", "c-Fos (9, J0la", "\"f Fosaliuded transuclivudict,", "this fIfect i6", "cach", "LHced", "thc #rcscnce", "the fusiou pratein", "be' devoid", "biological", "Qur Teauils", "Iudi -", "HACiunto", "roicreco", "ul ceirolem", "Cheds", "thc IEI pratein", "dircct,", "eXpr\"ssed in cellz in thc ahscnco", "ormono-rovcre-", "pcliv", "Mncia", "M", "Hgrmnan", "ible inhibitor of Fos and that estrogen", "etrols tne con-", "appropriate wild Vyn (W\") functioni was", "Akcrae iu", "reclored", "ncgativc", "UEI", "ditione", "uneilirc 0", "dounAn", "nctivitice", "harugn", "in thc", "prctcncc", "INA binding", "thc level", "thc possibilit;", "Fi ?", "Accordinely", "Wc explored", "thc aclivitins", "WT' end", "ccll lincs (hat stably cxptoss", "conely dcrivcrGbrnhlasi", "could I reculaled", "tranelationally", "mamlAtod", "ruemin", "Ws", "thc IFI prulcin exhibit reduced", "fnlri Iuto tnc", "Mfuni ('", "by fusion with tho FK", "Uun) chinioric nioloculo", "R croated", "quiosccnt", "of thc cell", "0s", "ni ' Ecruni", "ema", "trunculed", "crclc", "KK sucuLCO'", "Han", "apncndinp'", "WAA", "in the Alnent", "Thic", "ntad", "raruren", "conire", "thc Jun)-EK (IEI) fusion. Analy-is", "IEK", "rerulting", "suppOrt tha", "estrogcn-trcated controls_", "ncso rcsuil", "estrocet", "that", "for thc", "Jueinn", "nrolcn", "#hout", "doncnacni", "crclc", "hypathesis thnt Al\" Bn", "is imporlant", "cll", "uroeros-", "tranacription", "from AF] rcporlcr", "MchAe", "Constrct", "examining thc", "Rion", "Atid Drovido", "uniduc", "AnnTOAOn", "detailcd", "analysis of the nicchanism by which esto-", "addilioml;", "role of AF'] in thif proccss,", "IC", "pcrlorjucd", "Thc chimera", "nculale?", "Vtolci", "fortur het erodizuet? wilh WT\" Fos proteins but docs Jot readily", "hecruditcrs with WY Jun proicins. Hawevcr, ncither the", "familics of on oproleins Are tho", "For", "Melien", "LMc' Jun and", "IEK and W' Jun nor", "Cna", "Tulerachons ncucmi", "Elrone", "COI[OLCIIL ~ of the dimeric U ausc!iplion", "\"cti-", "CLCCWE", "Inctor", "interactions hctwccn IER and Fos are rCgulaled", "Vv (stroccn;", "prateit-", "(AF'T)\"", "Thc thrcc", "mucnut", "no Fut", "Fetc", "F", "corLTasL, IINA binding by HER homodimcrs", "FERFos", "complctcly stropen-dependent_", "elcrodincn-", "ccauc", "thi& novel", "\"clion; thc IFR fusion", "micchanisu", "prolein", "Fwllic Ilcaltl Scrvice", "Girnml;", "bupnorlt&", "JcGative protein that complexcs with Fos", "cilectvc", "DuIMMML", "UaKalatal", "lunitle", "Cirmn", "32in", "(e-ng", "IONA binding: #clivity- Ju addition,", "#IIc] reversiblt", "imniituts IS", "408u'", "4HU:'", "UaC", "Eaniceanaran_Amn", "Cant Moll FSn Glo-", "cell clones that slably express the IFF prolelo exhibit", "Myela (Juicolors", "neinecd", "Goela", "puwicalion", "want by thc payiuchl", "ailiclt #ert", "ucitalco", "cliaigs", "phasc from", "Gucr", "Froxth ATrestcd &lulc", "uuced CamaCIL", "arlicle tusl tnciclone", "hcrony nuirkoFaducelist !ch (", "Aaceuroamge", "rosult thal", "consislent", "witn", "in thc", "uuscnCC", "ealracen", "Ceclion ]734 &lchy", "Indicntt", "the hypothesis that AF]", "Joranal ccll", "cyclc", "IIIIiciriatL", "Felltw", "Itt Nalional Iuclitulcf", "Hcalih and nripicng", "METHII", "74-V219", "pruprt#SIuI", "Fcllow _", "thc Ancricnn Cancer Socicly:", "chimeras bclwccn", "steroid", "Whilc", "Mmtecr", "ticonne", "215-726-2889.", "T tom cotcemandcnccehould", "WldtetRL", "415724.36", "C;l, clurocor-", "TAHedar Mnacd AroA\"", "Actmnr #retm", "becco'& modilied Kaglcie wc-dium; FHS, Icta", "Fovine #crun; ]*, thyroid", "#TI ; wild ty \"c; rCipalyuctasc", "Wiculdrceuigr KK", "Ualncenecelant", "rolit oic ecid receptor,", "HIMKM, Iuk:", "dreaciol CATchlorennuhonicnl Acoretrenalcrasn", "horJlOIIC Tccenior_KAK", "11502", "PUBLICATIONS", "0050408" ]	[ [ 536, 44, 558, 52 ], [ 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362, 870, 462, 878 ], [ 337, 887, 375, 901 ], [ 528, 974, 668, 998 ], [ 699, 977, 772, 997 ] ]	[ "ol Min", "Jott4", "Au Aam", "Md-Tkn", "Atrhin Hnlur", "Analysis of the Hormone-dependent Regulation of a JunD)-Estrogen Receptor Chimcra (Ccc1ol pl liratiort Kovemlct Trecd orm Februaty 1995/", "Mary Xoy Francisi Honald Fhinncys_ Hnc Kevin Ryden Kotuc Far Ur AeMcnt Ccntct Wilorda Elamo 9] /", "The moduler ligand-hinding donains of steruid reccp elily CUM Jor nnd junl) unden\" 8lmt, Iore ar Ecncratemolein chimerne identical, regulation Cenc-Oa rotcis been widely uAcd trat share high tha ligund dependent for #clivily.In Finilat nilinie dcirc euttuIO acid Rpnuchce ~identity (11. '\"hcy Ara also sitna Uar Lcncrelcc Rcrice conditionally acl Hun) thcir irteraction with c-Fos and Fos-rclated proleins (2). mt Droldins by fusing tficI cnlvoxyl (( (OF)- u ut Jun Cox dimct comnicxcsmd IN at AF'] silcs Jarminn cnGE with (OOA-terminal fragmett Ad rckulia (tc' CutRRi0n LATE4 PnCS . Sirco arid Juan Trogcn rcctmor (EH) thntt conuins Uc ligund. amtily ncmticna rapidly Juduced n TcRuunso extrarciu binding domnin: Junl)EJe (IKII) nud Foir (FKI cki: lar Growth siunls tncy nic cinesuice imnncdiate cark IArX Hiti iulec Lauci zippcr Inic TEun snonE( Ecnt& Kxpression Lnce 0 Eenc Hamilies is exhihit hornon ~onenacn ctivalion aclnttur urO inlcgrul parl of a well-orchcstraled cascadc cvoras leading t0 tcin-]-dirceted trnuecription in transicni exprcSsion MR - ceulat pralilcratior 3nd Tclercnces unortiul Cci GhIc Ont AhteO fusions, IKK , hae no nramTICO pruem HEMIAICLAML Darlicinus the celluler Frowth dctnil decrmninc tucclaniem nction Uacus resunnuro furtoi Eludics analyzing thc direrl checls hese IT olfilittureonilion cxperimcnt: Wte Mrrane mroleing 0I FCIIO crnressiol Truwtn wania dcmonstratc that Ercatly Iromt HEK und Fos iranefccica cclls Cur facilitaled by a wcll characlcrizcd inducible expression syslem. Fos And IKI rendil, arneehntorutinicr omncxtR Onc #pproach for crcating inducible system lucuse : prisingly, the formntion Fos:II heterodimers; plucing te uctivity o protcin under Ihe control ofthc lieatd - #osRInC IFI Fnn] cclimcie troren-inarundcn, uding dumAI sleroid Wanlomo rectuior Ruch Howcvcr, Eel shift ASSAYR clcarly dcmonstrate that I)NA hincing AFI sitcs hy Fos:I)ER hctcrodimcrs IKI Elucocorlicoid receplor (GJ) (hc CstIOgch rereptor (KKA St - homodimcra cAtrogon-dopondena.Mor Ovcr, Ihcal- FCI hsimi urolems HaVC [icl crealed wilh proteins GcnCO cetroecn Inc nhi wrotcin un cflectivc inhil Such os FIA (4), c-Myc (54 the CCAATenhancer-binding \"f Fosaliuded transuclivudict, this fIfect i6 (61, Myol) (7), 053 (8L, and c-Fos (9, J0la cach LHced roicreco thc #rcscnce ul ceirolem Qur Teauils Iudi - Cheds the fusiou pratein HACiunto be' devoid biological M thc IEI pratein dircct, ormono-rovcre- pcliv Mncia eXpr\"ssed in cellz in thc ahscnco Hgrmnan ible inhibitor of Fos and that estrogen etrols tne con- Akcrae iu appropriate wild Vyn (W\") functioni was reclored ditione uneilirc 0 dounAn ncgativc nctivitice UEI in thc prctcncc harugn thc level INA binding Fi ? Accordinely Wc explored thc possibilit; thc aclivitins WT' end conely dcrivcrGbrnhlasi ccll lincs (hat stably cxptoss mamlAtod ruemin could I reculaled Ws tranelationally thc IFI prulcin exhibit reduced fnlri Iuto tnc Mfuni (' by fusion with tho FK Uun) chinioric nioloculo R croated of thc cell crclc Han quiosccnt 0s ni ' Ecruni ema apncndinp' trunculed WAA KK sucuLCO' ntad in the Alnent raruren Thic conire rerulting thc Jun)-EK (IEI) fusion. Analy-is IEK estrogcn-trcated controls_ ncso rcsuil suppOrt tha Jueinn nrolcn #hout that estrocet doncnacni for thc hypathesis thnt Al\" Bn is imporlant cll crclc uroeros- MchAe tranacription from AF] rcporlcr Constrct Rion Atid Drovido uniduc AnnTOAOn examining thc addilioml; detailcd analysis of the nicchanism by which esto- role of AF'] in thif proccss, nculale? IC Vtolci pcrlorjucd Thc chimera fortur het erodizuet? wilh WT\" Fos proteins but docs Jot readily hecruditcrs with WY Jun proicins. Hawevcr, ncither the Melien LMc' Jun and For familics of on oproleins Are tho Cna Tulerachons ncucmi IEK and W' Jun nor Elrone CLCCWE COI[OLCIIL ~ of the dimeric U ausc!iplion Inctor \"cti- interactions hctwccn IER and Fos are rCgulaled Vv (stroccn; F prateit- (AF'T)\" Thc thrcc mucnut no Fut Fetc corLTasL, IINA binding by HER homodimcrs FERFos elcrodincn- complctcly stropen-dependent_ ccauc thi& novel micchanisu \"clion; thc IFR fusion prolein bupnorlt& Fwllic Ilcaltl Scrvice Girnml; UaKalatal lunitle Cirmn cilectvc DuIMMML JcGative protein that complexcs with Fos 32in (e-ng 4HU:' 408u' UaC Eaniceanaran_Amn Cant Moll FSn Glo- #IIc] reversiblt imniituts IS IONA binding: #clivity- Ju addition, Myela (Juicolors neinecd Goela puwicalion cell clones that slably express the IFF prolelo exhibit ailiclt #ert ucitalco want by thc payiuchl cliaigs uuced CamaCIL Gucr phasc from Froxth ATrestcd &lulc arlicle tusl tnciclone hcrony nuirkoFaducelist !ch ( Aaceuroamge in thc uuscnCC ealracen rosult thal consislent witn Ceclion ]734 &lchy Indicntt METHII the hypothesis that AF] IIIIiciriatL Joranal ccll cyclc Felltw Itt Nalional Iuclitulcf Hcalih and nripicng 74-V219 pruprt#SIuI Fcllow _ thc Ancricnn Cancer Socicly: Whilc Mmtecr ticonne chimeras bclwccn steroid T tom cotcemandcnccehould WldtetRL 215-726-2889. 415724.36 TAHedar Mnacd AroA\" Actmnr #retm C;l, clurocor- Wiculdrceuigr KK Ualncenecelant #TI ; wild ty \"c; rCipalyuctasc becco'& modilied Kaglcie wc-dium; FHS, Icta Fovine #crun; ]*, thyroid dreaciol CATchlorennuhonicnl Acoretrenalcrasn HIMKM, Iuk: horJlOIIC Tccenior_KAK rolit oic ecid receptor,", "11502", "PUBLICATIONS", "0050408" ]	[ [ 536, 44, 558, 52 ], [ 60, 46, 88, 52 ], [ 102, 46, 156, 62 ], [ 586, 46, 630, 52 ], [ 230, 52, 290, 60 ], [ 42, 68, 653, 140 ], [ 101, 153, 441, 182 ], [ 44, 207, 659, 881 ], [ 337, 887, 375, 901 ], [ 528, 974, 668, 998 ], [ 699, 977, 772, 997 ] ]	6
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754	1,000	handwritten	[ "Dini", "lined", "of", "Oi:", "UL", "(LO", "Cotta", "UM", "oh", "Vee", "ef", "need", "Bove", "of", "AO", "pal", "ORE", "Hate", "seh", "bard", "ke", "ne", "nt", "he", "pi", "Ong", "omit", "ony", "ofp", "Hol", "Mend", "aad)", "Pine", "we", "Aan", "Lind", "fee", "aol", "Lani", ".", "\|", "yey", "MR", "\|", "\|", "\|" ]	[ [ 108, 113, 163, 136 ], [ 192, 120, 262, 138 ], [ 101, 145, 116, 175 ], [ 118, 149, 155, 170 ], [ 457, 155, 477, 174 ], [ 487, 155, 528, 179 ], [ 533, 145, 594, 183 ], [ 600, 153, 633, 177 ], [ 168, 186, 205, 198 ], [ 217, 186, 273, 197 ], [ 659, 189, 689, 200 ], [ 107, 212, 159, 230 ], [ 243, 219, 283, 229 ], [ 307, 221, 312, 230 ], [ 329, 220, 362, 230 ], [ 378, 217, 413, 230 ], [ 106, 241, 189, 260 ], [ 420, 247, 475, 262 ], [ 148, 280, 188, 292 ], [ 195, 280, 239, 300 ], [ 250, 280, 278, 293 ], [ 347, 275, 380, 293 ], [ 119, 318, 131, 323 ], [ 436, 311, 462, 325 ], [ 548, 319, 566, 325 ], [ 105, 338, 151, 356 ], [ 438, 344, 470, 356 ], [ 472, 336, 526, 373 ], [ 107, 368, 135, 394 ], [ 143, 373, 188, 396 ], [ 201, 371, 262, 390 ], [ 276, 377, 327, 397 ], [ 582, 374, 651, 391 ], [ 115, 406, 143, 414 ], [ 158, 403, 230, 416 ], [ 242, 400, 306, 418 ], [ 368, 402, 405, 420 ], [ 543, 399, 584, 418 ], [ 184, 436, 230, 447 ], [ 413, 421, 421, 428 ], [ 0, 544, 1, 547 ], [ 105, 515, 184, 553 ], [ 111, 556, 152, 575 ], [ 0, 614, 1, 623 ], [ 0, 634, 1, 646 ], [ 0, 647, 1, 655 ] ]	[ "Dini lined of Oi: UL (LO Cotta UM oh Vee ef need Bove of AO pal ORE Hate seh bard ke ne nt he pi Ong omit ony ofp Hol Mend aad) Pine we Aan Lind fee aol Lani . \| yey MR \| \| \|" ]	[ [ 0, 113, 689, 655 ] ]	3
1,000	777	presentation	[ "American Medical Association", "Physicians dedicated t0 Lhe heallh of Americz", "News Release", "FOR", "IMHEDIATE RELEASE", "For", "further", "inforoat ion ,", "Linda", "Cotsen,", "contacta", "312/464-4443", "Fingland", "202/245-7163", "HITHDRAHAL", "\"OLD JOE", "CAMEL", "ADS", "URGED", "AMA _", "0.$", "SURGEON", "GENERAL", "MASBINGTON,", "March", "ican", "Medical", "The", "Amer", "Asgociation", "and", "United", "States", "Surgeon", "General", "Novello,", "MPE , today", "Antonia", "called", "for", "the", "voluntary", "R.J_", "Reynolds", "advertising", "remoua", "Tobacco Company of", "al1", "using", "che", "Old", "Joe", "Cane [", "cigarettes", "character", "to pronote", "Novello urged all", "The", "AMA", "retail", "cigarette", "outlets", "cemove", "promot", "onal", "materials", "ing", "the ca", "fcom stores", "toon", "also", "charactor", "They", "asked", "Dagazines", "and", "neuspapers", "billboard compan", "Camel", "ads with", "refuse", "the", "O1d", "format", "Camel", "Joe", "Studies", "ished", "the Joucnal", "publ", "the", "Medical", "American", "4350c44t40n", "(JAHA)", "last", "December", "Old", "reported", "that", "Joe", "recogni", "ion", "factor", "among", "six-year-olds", "of the Disney", "equal", "their", "Identification", "4ag", "Hickey", "1o90", "Channel", "House", "related", "tudy shoved", "that", "advertiging", "Lobaccc", "ins", "promores", "anc", "Maint ?", "nicot ine", "addiction", "children", "amono", "1dolescents", "\"R.J. Reynolds", "4ing", "aoverta", "and", "Cancl cigarettes", "prOmot ion of", "has", "been", "targeting chfldren.", "James", "must", "sEoP ,", "Todd", "vicc", "R2ad", "exccutive", "ident", "the", "Reynolds", "tempt", "icism", "Prer", "ArA -", "R.J", "halt", "releasIng", "series of", "ads", "egedly", "designed", "ney", "dissuade", "chfldhood", "disingenuous", "and", "snokers", "smoke", "gcreen", "1", "mores", "615 North Stalc Surert", "Chiato,", "Ilnois 64510", "312464440" ]	[ [ 268, 70, 514, 94 ], [ 269, 99, 467, 113 ], [ 266, 166, 394, 190 ], [ 135, 243, 161, 257 ], [ 165, 243, 289, 257 ], [ 135, 271, 159, 285 ], [ 163, 271, 217, 285 ], [ 221, 271, 307, 285 ], [ 383, 273, 421, 287 ], [ 425, 273, 475, 285 ], [ 314, 274, 370, 282 ], [ 481, 275, 569, 287 ], [ 424, 286, 485, 304 ], [ 495, 289, 583, 303 ], [ 135, 315, 209, 327 ], [ 235, 315, 295, 329 ], [ 299, 315, 337, 329 ], [ 347, 315, 373, 329 ], [ 133, 329, 173, 341 ], [ 199, 329, 225, 341 ], [ 235, 329, 261, 341 ], [ 269, 329, 323, 343 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763 ], [ 335, 751, 395, 765 ], [ 421, 751, 459, 765 ], [ 546, 751, 585, 767 ], [ 128, 751, 158, 758 ], [ 252, 752, 280, 760 ], [ 302, 752, 324, 760 ], [ 483, 753, 515, 765 ], [ 130, 766, 197, 785 ], [ 245, 771, 311, 783 ], [ 315, 771, 339, 785 ], [ 365, 771, 409, 787 ], [ 413, 771, 471, 785 ], [ 216, 772, 238, 780 ], [ 497, 773, 555, 785 ], [ 561, 773, 629, 787 ], [ 209, 790, 295, 804 ], [ 301, 791, 325, 805 ], [ 130, 792, 180, 800 ], [ 343, 793, 381, 805 ], [ 386, 794, 432, 802 ], [ 691, 801, 711, 891 ], [ 384, 836, 420, 844 ], [ 567, 869, 659, 883 ], [ 567, 879, 603, 895 ], [ 605, 881, 663, 895 ], [ 567, 893, 621, 905 ] ]	[ "American Medical Association Physicians dedicated t0 Lhe heallh of Americz", "News Release", "FOR IMHEDIATE RELEASE", "For further inforoat ion , contacta", "Linda Cotsen, 312/464-4443 Fingland 202/245-7163", "HITHDRAHAL \"OLD JOE CAMEL ADS URGED AMA _ 0.$ SURGEON GENERAL", "MASBINGTON, March The Amer ican Medical Asgociation and United States Surgeon General Antonia Novello, MPE , today called for the voluntary remoua R.J_ Reynolds Tobacco Company of al1 advertising using che Old Joe Cane [ character to pronote cigarettes", "The AMA Novello urged all retail cigarette outlets cemove promot onal materials ing the ca toon charactor fcom stores They also asked Dagazines neuspapers and billboard compan refuse Camel ads with the O1d Joe Camel format", "Studies publ ished the Joucnal the American Medical 4350c44t40n (JAHA) last December reported that Old Joe recogni ion factor among six-year-olds 4ag equal their Identification of the Disney Channel Hickey House 1o90 related tudy shoved that Lobaccc advertiging promores anc Maint ? ins nicot ine addiction amono children 1dolescents", "\"R.J. Reynolds aoverta 4ing and prOmot ion of Cancl cigarettes has been targeting chfldren. must sEoP , R2ad James Todd exccutive vicc Prer ident the ArA - R.J Reynolds tempt halt icism releasIng ney series of ads egedly designed dissuade chfldhood snokers disingenuous and smoke gcreen", "1 Chiato, 615 North Stalc Surert 312464440 Ilnois 64510", "mores" ]	[ [ 268, 70, 514, 113 ], [ 266, 166, 394, 190 ], [ 135, 243, 289, 257 ], [ 135, 271, 370, 285 ], [ 383, 273, 583, 304 ], [ 133, 315, 379, 343 ], [ 132, 371, 653, 452 ], [ 133, 476, 675, 553 ], [ 131, 580, 673, 681 ], [ 128, 707, 654, 805 ], [ 566, 801, 711, 905 ], [ 384, 836, 420, 844 ] ]	12
754	1,000	budget	[ "New", "Tobacco", "Association", "1999", "Budget", "State", "Activities", "Division", "($000)", "Cost", "Center", "1400", "Account", "4300", "Rent", "-", "Office", "Space", "1999", "portion", "of", "lease", "obligations", "for", "six", "Tobacco", "Institute", "$37", "field", "offices.", "Office", "leases", "for", "three", "New", "Tobacco", "Association", "field", "90", "offices.", "(1,500", "s/f", "@", "$20", "x", "3)", "3127" ]	[ [ 249, 153, 280, 165 ], [ 285, 153, 346, 165 ], [ 352, 153, 434, 165 ], [ 297, 173, 330, 185 ], [ 337, 173, 387, 188 ], [ 250, 193, 289, 205 ], [ 294, 193, 365, 205 ], [ 371, 193, 432, 205 ], [ 315, 213, 361, 228 ], [ 81, 267, 111, 279 ], [ 116, 267, 160, 279 ], [ 170, 267, 202, 279 ], [ 71, 283, 140, 306 ], [ 169, 287, 202, 298 ], [ 212, 287, 244, 298 ], [ 249, 292, 253, 294 ], [ 258, 286, 299, 297 ], [ 304, 286, 347, 300 ], [ 83, 339, 116, 350 ], [ 122, 339, 170, 353 ], [ 176, 338, 189, 350 ], [ 195, 338, 232, 350 ], [ 237, 338, 314, 353 ], [ 319, 338, 338, 350 ], [ 343, 341, 362, 350 ], [ 367, 338, 429, 350 ], [ 435, 338, 490, 350 ], [ 569, 337, 595, 350 ], [ 81, 359, 109, 370 ], [ 116, 359, 161, 370 ], [ 81, 399, 122, 411 ], [ 129, 399, 174, 411 ], [ 179, 398, 198, 410 ], [ 203, 398, 240, 410 ], [ 246, 398, 277, 410 ], [ 281, 398, 342, 410 ], [ 348, 398, 431, 410 ], [ 436, 398, 465, 410 ], [ 578, 397, 595, 409 ], [ 81, 419, 127, 431 ], [ 142, 419, 187, 433 ], [ 193, 418, 210, 431 ], [ 215, 418, 229, 434 ], [ 236, 418, 261, 431 ], [ 267, 421, 274, 430 ], [ 280, 418, 293, 433 ], [ 560, 457, 595, 470 ] ]	[ "New Tobacco Association 1999 Budget State Activities Division ($000) Cost Center 1400 Account 4300 Rent - Office Space 1999 portion of lease obligations for six Tobacco Institute $37 field offices. Office leases for three New Tobacco Association field 90 offices. (1,500 s/f @ $20 x 3) 3127" ]	[ [ 71, 153, 595, 470 ] ]	10
754	1,000	specification	[ "LUXURY", "CR", "LTS)", "REGULAR", "Beans", "cone", "cucanerte", "woe", "ere", "15.6", "kop", "\|", "\"25.00", "Tonacco", "nop", "ve", "ve", "Tb.", "we", "20", "racer", "“Boe", "PAPER", "UPs", "MIITE", "TOL", "CER)", "XE", "256K2", "LASER", "PERF.", "REPLACE", "MITH", "TEAM", "X", "MITE", "TOL", "CCR)", "LASER", "PERT.", "uur", "+", "REFER", "TO", "ENGINEERINGS", "GLUE", "ROLLER", "VARIABLE", "PARTS", "CATALOG", "\|", "SY", "AND", "CIGARETTE.", "TYRE", "TPR.", "CUT", "Size", "TIPPING", "TIPPING", "ADHESIVE", "+", "NATIONAL", "32-2087", "ev", "sean", "+", "NATIONAL", "52-2100", "CPROTOS", "100/HK", "10)", "EVA.", "61-490-", "570.", "FILLER", "©", "PADK", "=", "18.60%", "VIRGINIA", "SLIME", "LIGHTS", "REGULAR", "Fr", "CHOAREYTE", "FLAX", "+", "sac", "FoR", "PRINT", "OTE", "AND", "EXPORT", "cute", "CRE", "DHE", "REF", "SAP", "CROSS" ]	[ [ 174, 140, 208, 147 ], [ 261, 140, 271, 147 ], [ 278, 140, 301, 147 ], [ 346, 140, 388, 147 ], [ 80, 154, 110, 160 ], [ 117, 154, 141, 161 ], [ 86, 195, 141, 202 ], [ 359, 195, 370, 202 ], [ 395, 195, 413, 202 ], [ 667, 194, 690, 201 ], [ 136, 208, 154, 215 ], [ 230, 210, 232, 215 ], [ 260, 208, 289, 215 ], [ 86, 221, 129, 228 ], [ 136, 221, 154, 228 ], [ 355, 205, 364, 240 ], [ 355, 219, 364, 254 ], [ 124, 263, 158, 270 ], [ 334, 263, 345, 270 ], [ 359, 263, 376, 270 ], [ 142, 276, 178, 283 ], [ 340, 276, 376, 283 ], [ 136, 317, 166, 324 ], [ 216, 317, 232, 324 ], [ 340, 317, 369, 324 ], [ 376, 317, 394, 324 ], [ 402, 317, 424, 324 ], [ 438, 317, 450, 324 ], [ 457, 317, 487, 324 ], [ 556, 316, 585, 324 ], [ 593, 316, 621, 324 ], [ 111, 331, 153, 338 ], [ 161, 331, 184, 338 ], [ 260, 331, 283, 338 ], [ 290, 331, 295, 338 ], [ 340, 331, 369, 338 ], [ 376, 331, 393, 338 ], [ 402, 331, 424, 338 ], [ 556, 331, 585, 338 ], [ 593, 331, 621, 337 ], [ 86, 358, 110, 365 ], [ 230, 363, 232, 365 ], [ 241, 358, 271, 365 ], [ 278, 358, 290, 365 ], [ 297, 358, 370, 365 ], [ 377, 358, 400, 364 ], [ 408, 358, 443, 364 ], [ 451, 357, 499, 364 ], [ 507, 357, 537, 364 ], [ 544, 357, 586, 364 ], [ 230, 374, 232, 378 ], [ 241, 372, 253, 378 ], [ 334, 372, 351, 378 ], [ 359, 371, 412, 378 ], [ 395, 398, 419, 406 ], [ 507, 398, 529, 405 ], [ 537, 398, 555, 405 ], [ 667, 398, 690, 405 ], [ 377, 412, 419, 419 ], [ 86, 439, 129, 446 ], [ 136, 439, 184, 446 ], [ 230, 444, 232, 446 ], [ 241, 439, 289, 446 ], [ 297, 439, 339, 446 ], [ 469, 439, 487, 446 ], [ 86, 466, 110, 473 ], [ 230, 469, 232, 471 ], [ 241, 467, 289, 474 ], [ 297, 467, 338, 474 ], [ 353, 467, 394, 473 ], [ 402, 466, 437, 473 ], [ 445, 466, 461, 473 ], [ 469, 466, 487, 473 ], [ 500, 466, 549, 473 ], [ 86, 493, 108, 500 ], [ 117, 493, 154, 500 ], [ 162, 496, 165, 498 ], [ 173, 494, 196, 500 ], [ 280, 496, 282, 498 ], [ 291, 493, 327, 500 ], [ 334, 493, 382, 500 ], [ 389, 493, 419, 500 ], [ 427, 493, 462, 500 ], [ 469, 493, 512, 500 ], [ 519, 493, 536, 500 ], [ 86, 534, 141, 542 ], [ 432, 534, 456, 541 ], [ 230, 567, 232, 569 ], [ 261, 562, 283, 569 ], [ 291, 562, 307, 569 ], [ 315, 561, 345, 569 ], [ 352, 561, 369, 569 ], [ 377, 562, 394, 569 ], [ 401, 561, 438, 569 ], [ 241, 575, 271, 583 ], [ 372, 575, 388, 582 ], [ 371, 603, 388, 610 ], [ 395, 602, 413, 610 ], [ 254, 713, 271, 720 ], [ 278, 713, 307, 720 ] ]	[ "LUXURY CR LTS) REGULAR Beans cone cucanerte woe ere 15.6 kop \| \"25.00 Tonacco nop ve ve Tb. we 20 racer “Boe PAPER UPs MIITE TOL CER) XE 256K2 LASER PERF. REPLACE MITH TEAM X MITE TOL CCR) LASER PERT. uur + REFER TO ENGINEERINGS GLUE ROLLER VARIABLE PARTS CATALOG \| SY AND CIGARETTE. TYRE TPR. CUT Size TIPPING TIPPING ADHESIVE + NATIONAL 32-2087 ev sean + NATIONAL 52-2100 CPROTOS 100/HK 10) EVA. 61-490- 570. FILLER © PADK = 18.60% VIRGINIA SLIME LIGHTS REGULAR Fr CHOAREYTE FLAX + sac FoR PRINT OTE AND EXPORT cute CRE DHE REF SAP CROSS REFERENCE 9: FILTER: 070198 contenrs PAPER REFLECTS CORE REDUCTION Wo PERF TAGS. EASON FOR «TRG PAPER UPDATED TO A PRESSURE DROP ci, a FS U/ 3 1 To REDUOE DILY AVG TO Ter. RENOVED, DEPLETED. MO TO DC CIGTS. = peanrane Date PREPARATION DATE SUPERCEDES SPECIFICATION 4/01/97" ]	[ [ 79, 140, 701, 954 ] ]	7
762	1,000	memo	[ "a>", "Qos", "(2)", "J.W,", "Dorygard", "i", "xt.", "pues", "peo", "Sty", "2050", "=", "sates", "voluce", "of", "6,751", "xeprosents", "on", "average", "204.4", "million", "per", "gay", "ao", "1867,", "or", "an", "\|", "Gherenve", "of", "202%", "i", "average", "and", "the", "parcent", "change", "MUSIC", "hae", "nonin", "of", "Lau", "cmtained", "28", "Sige", "wich", "the", "caye", "over", "29", "bolas", "a", "and", "32", "Gaye", "sith", "the", "ays", "20", "being", "=", "october", "1909", "1068", "GT", "Bayo)", "i", "aug", "Dolly", "to", "Brand", "Ya.", "1907", "i", "as", "se", "ee.", "wa", "ke", "re", "aD", "as", "=", "3", "ae", "as", "re", "you", "xo", "Fitter", "wee", "+", "2", "Boon", "ay.", "2", "o>", "st", "so", "0?" ]	[ [ 289, 187, 321, 202 ], [ 458, 185, 536, 204 ], [ 271, 220, 286, 229 ], [ 202, 243, 225, 250 ], [ 232, 241, 275, 251 ], [ 146, 262, 151, 274 ], [ 202, 294, 225, 302 ], [ 232, 294, 270, 301 ], [ 331, 278, 355, 311 ], [ 252, 304, 267, 312 ], [ 276, 303, 300, 310 ], [ 141, 313, 158, 326 ], [ 221, 361, 251, 368 ], [ 257, 359, 294, 368 ], [ 301, 359, 314, 367 ], [ 319, 359, 348, 368 ], [ 404, 360, 464, 368 ], [ 471, 361, 482, 366 ], [ 489, 361, 531, 368 ], [ 338, 371, 367, 378 ], [ 373, 371, 416, 378 ], [ 422, 373, 441, 380 ], [ 446, 371, 465, 380 ], [ 471, 371, 489, 378 ], [ 544, 370, 571, 379 ], [ 580, 371, 597, 378 ], [ 604, 372, 616, 378 ], [ 660, 368, 661, 376 ], [ 160, 384, 209, 392 ], [ 215, 384, 227, 392 ], [ 234, 384, 262, 392 ], [ 660, 381, 661, 389 ], [ 307, 408, 350, 415 ], [ 447, 406, 464, 413 ], [ 471, 406, 489, 413 ], [ 495, 407, 537, 415 ], [ 543, 405, 579, 415 ], [ 160, 419, 203, 429 ], [ 210, 419, 227, 427 ], [ 300, 418, 331, 425 ], [ 338, 418, 350, 425 ], [ 447, 417, 470, 425 ], [ 476, 417, 531, 425 ], [ 537, 417, 549, 425 ], [ 159, 431, 184, 440 ], [ 189, 431, 215, 439 ], [ 222, 431, 240, 438 ], [ 245, 430, 270, 439 ], [ 276, 431, 301, 437 ], [ 307, 430, 319, 437 ], [ 325, 429, 356, 438 ], [ 362, 431, 368, 437 ], [ 489, 429, 507, 436 ], [ 277, 441, 288, 449 ], [ 344, 441, 367, 450 ], [ 373, 440, 398, 448 ], [ 404, 441, 422, 448 ], [ 428, 441, 452, 449 ], [ 489, 441, 501, 448 ], [ 506, 440, 537, 449 ], [ 543, 442, 549, 448 ], [ 313, 464, 356, 474 ], [ 363, 464, 385, 471 ], [ 549, 464, 567, 470 ], [ 303, 475, 319, 484 ], [ 367, 475, 396, 484 ], [ 659, 480, 660, 485 ], [ 282, 488, 305, 496 ], [ 313, 487, 344, 496 ], [ 659, 486, 678, 493 ], [ 151, 490, 191, 517 ], [ 543, 498, 559, 505 ], [ 567, 498, 591, 505 ], [ 659, 496, 660, 499 ], [ 209, 535, 221, 542 ], [ 228, 535, 241, 542 ], [ 302, 533, 318, 541 ], [ 484, 533, 507, 540 ], [ 568, 532, 585, 540 ], [ 209, 546, 221, 553 ], [ 227, 546, 240, 553 ], [ 301, 548, 319, 550 ], [ 380, 559, 416, 561 ], [ 677, 553, 681, 556 ], [ 302, 568, 326, 575 ], [ 484, 567, 508, 575 ], [ 659, 564, 675, 585 ], [ 160, 592, 185, 599 ], [ 191, 592, 203, 599 ], [ 210, 591, 246, 599 ], [ 297, 590, 324, 597 ], [ 549, 591, 555, 596 ], [ 675, 587, 679, 595 ], [ 160, 603, 185, 611 ], [ 490, 601, 507, 609 ], [ 549, 605, 555, 606 ], [ 308, 613, 326, 620 ], [ 393, 616, 416, 618 ], [ 490, 612, 507, 620 ], [ 549, 615, 585, 618 ] ]	[ "a> Qos (2) J.W, Dorygard i xt. pues peo Sty 2050 = sates voluce of 6,751 xeprosents on average 204.4 million per gay ao 1867, or an \| Gherenve of 202% i average and the parcent change MUSIC hae nonin of Lau cmtained 28 Sige wich the caye over 29 bolas a and 32 Gaye sith the ays 20 being = october 1909 1068 GT Bayo) i aug Dolly to Brand Ya. 1907 i as se ee. wa ke re aD as = 3 ae as re you xo Fitter wee + 2 Boon ay. 2 o> st so 0? he uns Vasa . 28.0 + 3.0 i sane wa toed ene ro Fitter 327 ao Su 3 aS Se 2 TT ale “ALL 28 ~ 2 252.5 soe + 58 17 mae run nice uss Tatas oe eine (QUALITY OF THE FILMED. 3 10" ]	[ [ 28, 185, 681, 909 ] ]	15
778	1,000	questionnaire	[ "RESULTS", "\|", ".", "\|", "\|", "t", "\|", "a", "g", "\|", "5", "3", "\|", ".", "8", "\|", "3", "\|", "Be" ]	[ [ 363, 454, 415, 466 ], [ 0, 508, 2, 526 ], [ 617, 501, 619, 503 ], [ 0, 529, 2, 538 ], [ 1, 619, 2, 626 ], [ 1, 705, 2, 717 ], [ 1, 721, 2, 728 ], [ 740, 783, 750, 791 ], [ 739, 792, 749, 800 ], [ 0, 803, 2, 812 ], [ 738, 801, 748, 809 ], [ 737, 810, 747, 819 ], [ 1, 820, 2, 825 ], [ 602, 820, 608, 823 ], [ 736, 820, 746, 827 ], [ 0, 848, 3, 879 ], [ 732, 847, 743, 862 ], [ 0, 961, 1, 969 ], [ 0, 980, 655, 1000 ] ]	[ "RESULTS \| . \| \| t \| a g \| 5 3 \| . 8 \| 3 \| Be" ]	[ [ 0, 454, 750, 1000 ] ]	13
762	1,000	memo	[ "BROWN", "f&", "WILLIAMSON", "TOBACCO", "CORPORATION", "RESEARCH", "&", "DEVELOPMENT", "THTERNAL", "Tor.", "B.", "A.", "Reasor", "ce:", "A.", "H.", "L.", "Reynolds", "B.", "A.", "Kerr", "AL", "3.", "Golub", "H.C.", "Woerte", "A.", "P.", "L.", "Chen.", "A.", "Goodman", "DATE:", "November", "2,", "1990", "SUBJECT:", "DUPONE", "RESULTS", "FOR", "MENTHOL", "PERCEPTION", "BELATR", "LTS", "-", "RIGH/313", "DETAILS", "Attached", "are", "Monadic", "Attribute", "and", "analytical", "results,", "The", "following", "products", "were", "evaluated:", "313080", "~", "0.65%", "MENTHOL/CONTROL.", "313081", "—", "0.75%", "MENTHOL", "313082", "~", "0.82%", "MENTHOL", "313083", "-", "0.91%", "MENTEOL", "313084", "~", "1.00%", "MENTHOL", "Monadic", "Attribute", "ratings", "were", "made", "by", "54", "LD-M", "KS", "smokers", "and", "9", "PRISM", "paneliste.", "‘The", "Dupont", "study", "I.D.s", "were", "900253", "and" ]	[ [ 210, 93, 245, 102 ], [ 253, 93, 259, 100 ], [ 266, 91, 336, 100 ], [ 343, 90, 392, 99 ], [ 399, 88, 474, 98 ], [ 267, 119, 323, 128 ], [ 331, 119, 337, 126 ], [ 344, 117, 419, 126 ], [ 261, 146, 316, 154 ], [ 93, 203, 125, 211 ], [ 155, 202, 167, 210 ], [ 176, 201, 189, 210 ], [ 198, 201, 240, 209 ], [ 86, 219, 113, 246 ], [ 156, 228, 168, 236 ], [ 156, 242, 168, 250 ], [ 177, 241, 189, 250 ], [ 198, 240, 255, 251 ], [ 157, 255, 168, 263 ], [ 177, 255, 190, 263 ], [ 199, 255, 227, 263 ], [ 156, 269, 169, 277 ], [ 178, 268, 190, 276 ], [ 199, 267, 234, 276 ], [ 157, 282, 190, 290 ], [ 199, 281, 242, 290 ], [ 179, 296, 190, 304 ], [ 158, 310, 170, 318 ], [ 179, 309, 191, 317 ], [ 201, 309, 229, 317 ], [ 180, 336, 192, 344 ], [ 201, 335, 251, 344 ], [ 98, 365, 130, 374 ], [ 160, 363, 215, 372 ], [ 224, 362, 236, 373 ], [ 246, 362, 272, 370 ], [ 100, 392, 152, 401 ], [ 161, 390, 202, 399 ], [ 210, 389, 259, 399 ], [ 267, 389, 288, 397 ], [ 295, 387, 344, 397 ], [ 351, 385, 420, 395 ], [ 441, 384, 482, 393 ], [ 489, 383, 509, 392 ], [ 517, 387, 523, 389 ], [ 530, 381, 586, 390 ], [ 100, 434, 147, 444 ], [ 101, 460, 155, 470 ], [ 163, 462, 182, 468 ], [ 190, 459, 240, 468 ], [ 248, 457, 311, 467 ], [ 319, 456, 339, 464 ], [ 347, 454, 415, 465 ], [ 423, 453, 475, 462 ], [ 491, 452, 511, 460 ], [ 520, 450, 581, 460 ], [ 102, 475, 156, 486 ], [ 163, 476, 190, 482 ], [ 199, 472, 267, 481 ], [ 235, 499, 276, 508 ], [ 284, 503, 291, 504 ], [ 299, 497, 333, 506 ], [ 340, 495, 444, 505 ], [ 236, 512, 276, 521 ], [ 285, 516, 291, 517 ], [ 299, 511, 334, 519 ], [ 341, 509, 389, 519 ], [ 236, 526, 277, 535 ], [ 285, 529, 292, 531 ], [ 300, 524, 334, 533 ], [ 341, 523, 390, 532 ], [ 236, 540, 277, 549 ], [ 285, 543, 292, 545 ], [ 300, 538, 335, 547 ], [ 342, 536, 390, 545 ], [ 237, 553, 278, 563 ], [ 286, 557, 292, 559 ], [ 301, 552, 335, 561 ], [ 342, 550, 390, 559 ], [ 104, 583, 152, 592 ], [ 159, 582, 222, 591 ], [ 231, 580, 279, 590 ], [ 286, 582, 314, 587 ], [ 321, 578, 350, 587 ], [ 357, 578, 370, 587 ], [ 378, 577, 391, 585 ], [ 398, 576, 426, 585 ], [ 433, 576, 445, 584 ], [ 454, 575, 501, 584 ], [ 509, 574, 529, 582 ], [ 537, 574, 543, 582 ], [ 105, 597, 139, 606 ], [ 146, 596, 214, 607 ], [ 105, 625, 125, 633 ], [ 133, 624, 172, 634 ], [ 182, 623, 216, 632 ], [ 224, 622, 258, 631 ], [ 266, 622, 294, 629 ], [ 302, 619, 343, 628 ], [ 352, 618, 371, 627 ] ]	[ "BROWN f& WILLIAMSON TOBACCO CORPORATION RESEARCH & DEVELOPMENT THTERNAL Tor. B. A. Reasor ce: A. H. L. Reynolds B. A. Kerr AL 3. Golub H.C. Woerte A. P. L. Chen. A. Goodman DATE: November 2, 1990 SUBJECT: DUPONE RESULTS FOR MENTHOL PERCEPTION BELATR LTS - RIGH/313 DETAILS Attached are Monadic Attribute and analytical results, The following products were evaluated: 313080 ~ 0.65% MENTHOL/CONTROL. 313081 — 0.75% MENTHOL 313082 ~ 0.82% MENTHOL 313083 - 0.91% MENTEOL 313084 ~ 1.00% MENTHOL Monadic Attribute ratings were made by 54 LD-M KS smokers and 9 PRISM paneliste. ‘The Dupont study I.D.s were 900253 and 900254, COMMENTS None. } P. A. Goodman 26171 505501605" ]	[ [ 86, 88, 666, 872 ] ]	15
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754	1,000	form	[ "INBIFO", "Institut", "far", "biologlsche", "Forschung", "-", "Kétn", "es", "TMU", "=", "a", "ne", "3", "2", "LS", "ai", "7”", "*", "§", "8", "Abs.", "§", "9", "Nr.", "8", "me" ]	[ [ 139, 78, 175, 106 ], [ 177, 78, 222, 106 ], [ 226, 78, 238, 106 ], [ 242, 78, 315, 106 ], [ 319, 78, 381, 106 ], [ 382, 78, 392, 106 ], [ 400, 87, 426, 96 ], [ 32, 206, 70, 224 ], [ 380, 613, 408, 622 ], [ 157, 685, 241, 686 ], [ 40, 708, 56, 715 ], [ 239, 693, 254, 723 ], [ 657, 705, 679, 719 ], [ 102, 795, 114, 804 ], [ 659, 803, 674, 811 ], [ 101, 834, 116, 854 ], [ 102, 847, 113, 867 ], [ 147, 850, 149, 854 ], [ 160, 852, 165, 861 ], [ 169, 853, 175, 860 ], [ 174, 852, 197, 861 ], [ 258, 846, 269, 867 ], [ 270, 846, 278, 867 ], [ 277, 852, 294, 861 ], [ 300, 853, 306, 860 ], [ 586, 882, 604, 885 ] ]	[ "INBIFO Institut far biologlsche Forschung - Kétn es TMU = a ne 3 2 LS ai 7” * § 8 Abs. § 9 Nr. 8 me" ]	[ [ 32, 78, 679, 885 ] ]	1
1,000	788	budget	[ "LEO BURNETT U.S.A.", "companr inc", "DlabiUR", "duR NETT", "ADVERTISING", "MAGAZINE", "EStimate", "RECAP", "(C)", "PERICD", "DATE", "10/3+/86", "01/01/85 To", "12/31/85", "PAGE", "CLIENT", "INc", "OFFICE", "DESC ;", "7024", "Marlborc 25'$", "RED/LT", "EST NC ;", "5016 RevIses EsT DtD", "09/12/86", "REGNS", "SUpPS 522", "Totals BY projuct/Month", "ON SaL} DatE", "GROSS", "Gross", "GRoss", "PRODUCT", "PERIOD", "AMCUNT", "CHANGE", "LESS", "c/d", "I0-MARLBORC", "1985", "827", "743.63", "JEC", "819", "802. 369", "794", "CU-RTER", "630 , * 13", "456", "558.038", "587.57 <", "581 ,575", "QUARTER", "147 . 129.32", "136,614", "NOV", "686", "686", "DEC", "343", "343.Co", "QuaRTER", "029 ,0o", "25.029 . Oo", "Total", "2.802,271.66", "778 ,099,75", "1", "FCRM M-01", "05-R2" ]	[ [ 79, 25, 267, 45 ], [ 205, 43, 269, 57 ], [ 92, 44, 128, 52 ], [ 164, 44, 202, 52 ], [ 130, 55, 218, 69 ], [ 374, 67, 431, 84 ], [ 497, 71, 553, 85 ], [ 557, 73, 595, 85 ], [ 645, 73, 669, 85 ], [ 455, 93, 499, 107 ], [ 569, 95, 601, 109 ], [ 613, 95, 669, 109 ], [ 401, 103, 479, 117 ], [ 483, 105, 539, 119 ], [ 571, 105, 601, 119 ], [ 165, 125, 209, 137 ], [ 259, 125, 283, 137 ], [ 313, 127, 357, 139 ], [ 455, 127, 491, 141 ], [ 495, 127, 525, 141 ], [ 529, 129, 619, 141 ], [ 623, 129, 667, 143 ], [ 165, 135, 215, 149 ], [ 225, 135, 365, 149 ], [ 373, 137, 431, 151 ], [ 495, 139, 533, 153 ], [ 603, 139, 667, 153 ], [ 165, 179, 323, 195 ], [ 197, 203, 283, 217 ], [ 399, 239, 437, 251 ], [ 501, 241, 537, 253 ], [ 609, 241, 645, 255 ], [ 211, 247, 261, 261 ], [ 305, 249, 349, 263 ], [ 399, 251, 443, 263 ], [ 501, 251, 545, 265 ], [ 595, 253, 625, 267 ], [ 629, 253, 653, 267 ], [ 185, 271, 261, 283 ], [ 327, 273, 355, 285 ], [ 385, 273, 409, 285 ], [ 413, 273, 455, 287 ], [ 298, 274, 320, 282 ], [ 589, 275, 611, 289 ], [ 385, 285, 435, 297 ], [ 587, 287, 611, 299 ], [ 297, 293, 349, 307 ], [ 385, 295, 435, 309 ], [ 614, 300, 636, 308 ], [ 587, 321, 637, 333 ], [ 385, 329, 435, 341 ], [ 587, 331, 637, 345 ], [ 297, 339, 347, 351 ], [ 385, 339, 455, 353 ], [ 587, 343, 637, 357 ], [ 297, 361, 321, 373 ], [ 411, 363, 435, 375 ], [ 613, 367, 637, 379 ], [ 296, 374, 318, 382 ], [ 411, 375, 435, 387 ], [ 613, 377, 657, 391 ], [ 295, 383, 347, 397 ], [ 411, 385, 455, 399 ], [ 593, 387, 657, 401 ], [ 309, 407, 347, 419 ], [ 369, 407, 455, 421 ], [ 585, 409, 657, 425 ], [ 742, 818, 766, 928 ], [ 25, 973, 81, 985 ], [ 106, 974, 132, 982 ] ]	[ "LEO BURNETT U.S.A. DlabiUR duR NETT companr inc ADVERTISING", "MAGAZINE", "EStimate RECAP", "(C)", "PERICD 01/01/85 To 12/31/85", "DATE 10/3+/86 PAGE", "CLIENT INc OFFICE EST NC ; 5016 RevIses EsT DtD 09/12/86", "DESC ; 7024 Marlborc 25'$ RED/LT REGNS SUpPS 522", "Totals BY projuct/Month ON SaL} DatE", "GROSS AMCUNT", "Gross CHANGE", "GRoss LESS c/d", "PRODUCT", "PERIOD", "I0-MARLBORC", "JEC 1985", "827 743.63 802. 369 630 , * 13", "819 794 456", "CU-RTER", "558.038 581 ,575 136,614", "587.57 < 147 . 129.32", "QUARTER", "NOV DEC QuaRTER", "686 343 029 ,0o", "686 343.Co 25.029 . Oo", "Total", "2.802,271.66", "778 ,099,75", "1", "FCRM M-01", "05-R2" ]	[ [ 79, 25, 269, 69 ], [ 374, 67, 431, 84 ], [ 497, 71, 595, 85 ], [ 645, 73, 669, 85 ], [ 401, 93, 539, 119 ], [ 569, 95, 669, 119 ], [ 165, 125, 431, 151 ], [ 455, 127, 667, 153 ], [ 165, 179, 323, 217 ], [ 399, 239, 443, 263 ], [ 501, 241, 545, 265 ], [ 595, 241, 653, 267 ], [ 211, 247, 261, 261 ], [ 305, 249, 349, 263 ], [ 185, 271, 261, 283 ], [ 298, 273, 355, 285 ], [ 385, 273, 455, 309 ], [ 587, 275, 636, 308 ], [ 297, 293, 349, 307 ], [ 587, 321, 637, 357 ], [ 385, 329, 455, 353 ], [ 297, 339, 347, 351 ], [ 295, 361, 347, 397 ], [ 411, 363, 455, 399 ], [ 593, 367, 657, 401 ], [ 309, 407, 347, 419 ], [ 369, 407, 455, 421 ], [ 585, 409, 657, 425 ], [ 742, 818, 766, 928 ], [ 25, 973, 81, 985 ], [ 106, 974, 132, 982 ] ]	10
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OKLAHOMA th MISSISSIPPI MINNESOTA NEBRASKA COLORADO TEXAS LOUISIANA SOUTH DAKOTA WYOMING NEW MEXICO” § FLORIDA: The following Counties: 3 Holmes Washington Bay Santa Rosa Watton Jackson cult ILLINOIS: The following Counties: Madison Moncoe : Except Scott County * WISCONSIN: Douglas County only, KENT got it all together again . . . NOW THERE'S KENT MENTHOL KING SIZE TOO! with the exclusive Micronite Filter .. . and the good rich taste of KENT. We've taken all the good things of KENT MENTHOL ig 1100's, and got them together for sniokers who prefer KING-SIZE. LIST PRICE: $10.25 per M. TERMS: ‘We will allow special discount terms as follows: THE TOTAL 3% DISCOUNT WILL BE AVAILABLE ON 4NVOICES FOR KENT MENTHOL KING SIZE DATED. THROUGH MAY 26, 1971. 1F PAYMENT IS RECEIVED AT OUR REMITTANCE ADDRESS NO LATER THAN THE 30TH DAY AFTER INVOICE DATE. ‘THESE SPECIAL TERIAS WILL APPLY ONLY TO KENT MENTHOL KING SIZE LS TO PURCHASES UP 10 THE AMOUNT OF YOUR ALLOCATION. PACKING: KING SIZE Cup (soft) packages of 20's, cartons of 200, shipping containers SHIPMENTS: First deliveries of KENT MENTHOL KING SIZE Cigarettes will be made May td 13, 1971 to Lorillard customers in the areas outlined above. ALLOWANCE: — An Introductory allowance of per M ($6.00 per case of 12M) will be \| BW given on KENT MENTHOL KING SIZE Cigarettes beginning May 13, 1971 oe through May 28, 1971, This allowance will be deducted ftom the face of invoices and applies to purchases of KET MENTHOL KING SIZE only. i Pa gfe - . 7 ve" ]	[ [ 16, 39, 739, 961 ] ]	0
1,000	774	form	[ "RJRI INI , INC,", "aJ:", "Reynolds Tobacco Interational Inc", "Feb", "1902", "TI Rc", "RUr", "Form 0d0]", "Jjrt", "CHANGT/2-82", "Den", "fion", "AUTHORIZATION FoR", "January 21 ,", "1982", "Area", "III", "Brazi]", "002-82", "Date", "BR", "Operating Area /Unit", "AC No_", "New_Brand Introduction (Test Market)", "Came]", "Filters", "MAP-9-1982", "Subject /Location", "Unit Ref.", "Approvab", "Requested", "Rpreve\"", "This", "request", "for the introduction of Came", "Filters into the Curitiba", "Test Market", "1982", "on Apri", "the", "introduction of Came", "Filters", "the", "brand group wants", "to tes", "dentified,", "exploiting", "marke", "that has", "recently been", "Specifically", "the", "brand group", "Camepportunity", "to test", "Filters", "proposes", "an alternative to Ho]lywood", "eydvanesgeb9ishc", "taking", "of Ho] Iywood", "product Tife", "Moreover", "maturity", "Filters has", "Came", "opoo", "unique", "portunity", "itself", "ma le cigarette without", "the", 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372, 838 ], [ 230, 812, 268, 838 ], [ 27, 815, 111, 833 ], [ 480, 818, 528, 844 ], [ 105, 833, 191, 869 ], [ 304, 836, 350, 866 ], [ 208, 838, 288, 870 ], [ 461, 840, 536, 876 ], [ 24, 842, 97, 863 ], [ 100, 858, 159, 905 ], [ 222, 869, 286, 901 ], [ 49, 877, 83, 891 ], [ 159, 881, 217, 899 ], [ 240, 902, 284, 926 ], [ 47, 902, 73, 923 ], [ 49, 939, 89, 957 ], [ 27, 971, 89, 987 ] ]	[ "RJRI INI , INC,", "aJ: Reynolds Tobacco Interational Inc Feb TI Rc 1902 Jjrt Form 0d0] RUr CHANGT/2-82 AUTHORIZATION FoR Den fion Date January 21 , 1982 Operating Area /Unit Area III Brazi] AC No_ BR 002-82 Subject /Location New_Brand Introduction (Test Market) Came] Filters Unit Ref. MAP-9-1982", "Approvab Requested This request Rpreve\" for the introduction of Came Filters into the Curitiba Test Market on Apri 1982 the introduction of Came Filters the brand group wants to tes exploiting marke Camepportunity that has recently been dentified, Specifically the brand group proposes to test Filters an alternative to Ho]lywood taking eydvanesgeb9ishc of Ho] Iywood product Tife maturity Moreover Came Filters has unique opoo portunity itself ma le cigarette without the usua Iy negative perceptions of and too downscale Currently there no cigarette in the market with such unique 9659893 oning If after twenty our weeks Came] Filters achieves its 0 SOM objective and has shown ievel, tnat can sustain this share the brand wil) be ro] led-out nationa ly on October 25, 1982", "L-J+I", "(Attach Summar Discussion ol Roporal)", "Type of Change Selling Price Change Expense Chenge Raw Materials Salary. Wage Scales Fringe Benefits Headcount Change Other Policy Change LX New Product Introduction", "Contractua Commitment (Specify Type) Working Capital Change Inventories Receivables Other Amount of Change: Change from Budget /Plan: Other ,_", "0 {", "BEST COPY ,", "Is this lated previous proposal? Will subsequent commitments required?", "Yes Yes", "Yes, describe attached Iummtn diccussion", "Initia Post Evaluation Date Sept_22 982 VHENY AHNU 19 86 3,416 1,845 3,416", "19_82 637 884 322", "19 85 2,643 1.427 2,643", "Eximuted Profit/Loss lmpuct: Earnings From Operations Earnings From Operations(Aftax) Budoet /Plan EFO Change", "738) (399) (738)", "430", "232 430", "APPROVALS OPERATING UniT AREA H.a: Signature Date Signature Date Signature Brand Mgnt. Jo_LL Ji2sL Pig:Pla ' Yi44 Pir.Lega] RI eez] EE82 xhbx Oper_ Iixa Zneb Lsla Fin Liky", "RJrTi", "Date", "Mktg.", "Rres idew" ]	[ [ 630, 14, 738, 38 ], [ 33, 41, 738, 187 ], [ 33, 201, 771, 359 ], [ 318, 371, 445, 396 ], [ 287, 423, 513, 439 ], [ 31, 449, 267, 589 ], [ 460, 453, 645, 589 ], [ 731, 461, 749, 555 ], [ 353, 481, 420, 545 ], [ 31, 603, 259, 633 ], [ 339, 603, 363, 633 ], [ 410, 605, 555, 631 ], [ 589, 605, 773, 729 ], [ 231, 643, 269, 727 ], [ 507, 645, 559, 729 ], [ 30, 647, 209, 731 ], [ 333, 665, 375, 729 ], [ 433, 667, 459, 681 ], [ 433, 689, 459, 727 ], [ 24, 749, 599, 926 ], [ 637, 775, 677, 789 ], [ 735, 795, 763, 807 ], [ 49, 939, 89, 957 ], [ 27, 971, 89, 987 ] ]	1
1,000	754	presentation	[ "12/s(14", "(BAPensATin", "KozolouJJk ;", "DveArEads", "Compensation", "Compensation and Low", "Yield Cigarettes", "Lynn \"", "Kodowekl PhD:", "Does", "brand-swilching", "Prolateot4nd Hled", "smoker", "oversmoke", "Progrm", "Blobahavoral Haaltn", "lower nicotina cigaretto?", "Colleot-", "Haalth end Human Davelopmani", "Th Pennaylvnui sub Unlvrlty", "Answor: Yes:", "Unlverelly Perk PA 16402", "Ground Rules", "\"Hydraulics\"", "Per clgarotto adjustments only", "The FTC Iost @ 4 por-clgaratto tost", "approximate what would happen If", "should be judgad", "Ruch", "number ot cigarettes were fixed_", "Forty low calorle candy ban May", "~2 mg X 20 cigs", "mglday", "togolhar be hlgh calorle and atIII", "~4mg X 10 cigs", "mglday", "Indlvidually bt low calorlo.", "~0.8 mg X 5 cigs", "mgday", "Importance of brand-", "Compensatory % Chango in", "Cigarettes per Day", "switching research_", "Repeated-measures deelgns", "Mean", "+15%", "control Ior individual dlilerences:", "(95% Cl=t6)", "~dnug Motabollem", "brnd golaetlon", "blaser", "(#ussortatlve mating )", "[No decreased intake]", "Page", "89241644" ]	[ [ 514, 102, 570, 126 ], [ 409, 109, 505, 123 ], [ 219, 111, 303, 127 ], [ 307, 111, 377, 125 ], [ 402, 224, 568, 254 ], [ 141, 225, 305, 241 ], [ 165, 237, 279, 257 ], [ 125, 273, 153, 287 ], [ 161, 273, 237, 287 ], [ 397, 273, 431, 289 ], [ 443, 273, 545, 289 ], [ 125, 287, 217, 299 ], [ 403, 287, 453, 303 ], [ 459, 287, 531, 303 ], [ 124, 298, 167, 314 ], [ 177, 299, 271, 311 ], [ 403, 301, 559, 317 ], [ 125, 313, 163, 325 ], [ 171, 313, 313, 325 ], [ 125, 325, 279, 337 ], [ 397, 331, 485, 347 ], [ 125, 337, 241, 351 ], [ 150, 452, 296, 476 ], [ 418, 452, 554, 482 ], [ 387, 483, 557, 499 ], [ 141, 493, 313, 507 ], [ 392, 494, 587, 514 ], [ 171, 505, 261, 519 ], [ 274, 506, 300, 514 ], [ 393, 509, 571, 525 ], [ 141, 535, 307, 549 ], [ 397, 535, 497, 551 ], [ 515, 537, 561, 551 ], [ 139, 545, 303, 559 ], [ 397, 553, 497, 569 ], [ 515, 553, 561, 569 ], [ 141, 555, 275, 569 ], [ 397, 569, 491, 585 ], [ 509, 569, 555, 585 ], [ 397, 675, 577, 696 ], [ 145, 677, 303, 695 ], [ 171, 691, 277, 707 ], [ 403, 695, 567, 715 ], [ 387, 717, 547, 733 ], [ 152, 722, 212, 746 ], [ 228, 722, 290, 746 ], [ 393, 729, 581, 745 ], [ 150, 750, 278, 778 ], [ 397, 753, 487, 767 ], [ 449, 781, 529, 795 ], [ 403, 783, 439, 795 ], [ 409, 797, 521, 811 ], [ 153, 811, 291, 827 ], [ 333, 880, 369, 898 ], [ 545, 881, 629, 901 ] ]	[ "(BAPensATin 12/s(14", "KozolouJJk ; DveArEads", "Compensation", "Compensation and Low Yield Cigarettes", "Lynn \" Kodowekl PhD: Prolateot4nd Hled Progrm Blobahavoral Haaltn Colleot- Haalth end Human Davelopmani Th Pennaylvnui sub Unlvrlty Unlverelly Perk PA 16402", "Does brand-swilching smoker oversmoke lower nicotina cigaretto?", "Answor: Yes:", "Ground Rules", "\"Hydraulics\" Per clgarotto adjustments only approximate what would happen If number ot cigarettes were fixed_ ~2 mg X 20 cigs mglday ~4mg X 10 cigs mglday ~0.8 mg X 5 cigs mgday", "The FTC Iost @ 4 por-clgaratto tost should be judgad Ruch", "Forty low calorle candy ban May togolhar be hlgh calorle and atIII Indlvidually bt low calorlo.", "Importance of brand- switching research_ Repeated-measures deelgns control Ior individual dlilerences: ~dnug Motabollem", "Compensatory % Chango in Cigarettes per Day", "Mean +15% (95% Cl=t6)", "blaser brnd golaetlon (#ussortatlve mating )", "[No decreased intake]", "Page", "89241644" ]	[ [ 409, 102, 570, 126 ], [ 219, 111, 377, 127 ], [ 402, 224, 568, 254 ], [ 141, 225, 305, 257 ], [ 124, 273, 313, 351 ], [ 397, 273, 559, 317 ], [ 397, 331, 485, 347 ], [ 150, 452, 296, 476 ], [ 387, 452, 587, 585 ], [ 141, 493, 313, 519 ], [ 139, 535, 307, 569 ], [ 387, 675, 581, 767 ], [ 145, 677, 303, 707 ], [ 150, 722, 290, 778 ], [ 403, 781, 529, 811 ], [ 153, 811, 291, 827 ], [ 333, 880, 369, 898 ], [ 545, 881, 629, 901 ] ]	12
718	1,000	scientific publication	[ "Jounal", "of", "$13", "(1993)", "95103", "Evie", "BV,", "Amsterdam", "chromato,", "High-performance", "liquid", "chromatographic", "determination", "of", "nicotine", "and", "its", "urinary", "metabolites", "via", "their", "1,3-", "diethyl-2-thiobarbituric", "acid", "derivatives", "Klaus", "Rustemeier*,", "Demetrios", "Demetriou,", "Georg", "Schepers", "and", "Peter", "Voncken", "fr", "2,", "W-S000", "Kan", "90", "(Fi", "ane", "288,", "1992;", "November", "TR,", "1992)", "ABSTRACT", "‘The", "\|", "igh", "fr", "rictne", "ha", "been", "hat", "ican", "be", "wed", "determine", "the", "concentration", "of", "nine", "nd", "upto", "1", "bole", "ine", "urn", "of", "humane", "ne", "Wbortoy", "ail,", "plate", "tebe", "“Th", "produts", "of", "lavage", "found", "in", "ite", "vere", "nil", "ene", "cosine.", "aa", "sal", "mount", "Felloving", "anaes", "showed", "the", "ofthe", "rietne", "DETEA", "dernatne", "1", "te" ]	[ [ 58, 95, 89, 103 ], [ 90, 82, 96, 113 ], [ 177, 96, 191, 103 ], [ 194, 96, 220, 104 ], [ 223, 96, 250, 103 ], [ 59, 121, 90, 129 ], [ 173, 121, 193, 129 ], [ 197, 121, 243, 129 ], [ 58, 152, 115, 159 ], [ 59, 189, 228, 210 ], [ 236, 189, 285, 210 ], [ 294, 189, 451, 210 ], [ 459, 190, 585, 206 ], [ 59, 215, 79, 232 ], [ 85, 215, 158, 232 ], [ 166, 215, 199, 231 ], [ 207, 215, 227, 232 ], [ 235, 215, 299, 235 ], [ 307, 215, 411, 232 ], [ 420, 215, 446, 231 ], [ 454, 216, 495, 232 ], [ 505, 216, 535, 235 ], [ 59, 240, 273, 261 ], [ 281, 241, 317, 256 ], [ 325, 241, 423, 257 ], [ 59, 284, 95, 295 ], [ 101, 284, 180, 297 ], [ 186, 285, 248, 295 ], [ 254, 284, 320, 296 ], [ 327, 284, 365, 297 ], [ 370, 285, 423, 298 ], [ 429, 285, 450, 295 ], [ 456, 285, 486, 295 ], [ 491, 285, 544, 295 ], [ 127, 306, 140, 316 ], [ 295, 306, 299, 314 ], [ 306, 306, 337, 314 ], [ 341, 307, 359, 314 ], [ 363, 307, 372, 314 ], [ 58, 324, 67, 355 ], [ 121, 337, 139, 345 ], [ 144, 337, 164, 346 ], [ 169, 338, 188, 347 ], [ 307, 337, 350, 345 ], [ 354, 338, 370, 345 ], [ 378, 337, 399, 346 ], [ 58, 382, 112, 390 ], [ 68, 407, 83, 415 ], [ 88, 408, 89, 415 ], [ 94, 407, 129, 417 ], [ 286, 407, 297, 415 ], [ 301, 409, 333, 415 ], [ 384, 394, 393, 425 ], [ 396, 408, 419, 415 ], [ 476, 408, 490, 415 ], [ 494, 410, 515, 415 ], [ 519, 408, 527, 415 ], [ 531, 408, 547, 415 ], [ 562, 409, 601, 416 ], [ 59, 420, 70, 428 ], [ 73, 422, 134, 428 ], [ 135, 407, 142, 438 ], [ 143, 420, 180, 428 ], [ 184, 421, 198, 428 ], [ 202, 423, 223, 430 ], [ 227, 421, 234, 428 ], [ 238, 420, 282, 428 ], [ 286, 420, 307, 428 ], [ 311, 423, 331, 428 ], [ 334, 420, 343, 428 ], [ 346, 420, 377, 428 ], [ 380, 423, 395, 428 ], [ 398, 421, 440, 430 ], [ 444, 421, 475, 428 ], [ 520, 421, 542, 430 ], [ 553, 421, 598, 429 ], [ 58, 433, 74, 440 ], [ 77, 433, 112, 442 ], [ 115, 433, 131, 442 ], [ 194, 433, 228, 443 ], [ 231, 433, 253, 441 ], [ 256, 435, 263, 440 ], [ 302, 419, 316, 450 ], [ 317, 419, 334, 450 ], [ 345, 433, 367, 442 ], [ 371, 434, 398, 441 ], [ 462, 435, 509, 442 ], [ 512, 434, 532, 441 ], [ 536, 436, 551, 441 ], [ 557, 419, 587, 450 ], [ 98, 446, 139, 456 ], [ 244, 446, 276, 456 ], [ 280, 446, 309, 453 ], [ 314, 446, 326, 454 ], [ 371, 446, 395, 454 ], [ 400, 448, 431, 454 ], [ 437, 446, 469, 454 ], [ 474, 448, 512, 454 ], [ 517, 449, 524, 455 ], [ 529, 447, 537, 454 ] ]	[ "Jounal of $13 (1993) 95103 Evie BV, Amsterdam chromato, High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3- diethyl-2-thiobarbituric acid derivatives Klaus Rustemeier, Demetrios Demetriou, Georg Schepers and Peter Voncken fr 2, W-S000 Kan 90 (Fi ane 288, 1992; November TR, 1992) ABSTRACT ‘The \| igh fr rictne ha been hat ican be wed determine the concentration of nine nd upto 1 bole ine urn of humane ne Wbortoy ail, plate tebe “Th produts of lavage found in ite vere nil ene cosine. aa sal mount Felloving anaes showed the ofthe rietne DETEA dernatne 1 te ie ef DESTA an the wk of nicotine INTRODUCTION low [6] reported that, by using an extraction pro- cedure, the sensitivity of the assay was enhanced, In recent years the metabolism of nicotine has et af, [7], in addition to determining been found to be very complex, Moré than 20 nicotine and cotinine, were able 10 determine urinary nicotine metabolites have been described three identified metabolites vsing modified chro- (1). For their determination in the urine of hu- matographie conditions. Barlow er al. {5} and mans and laboratory animals, an appropriate O'Doherty eral (7] proposed that the mechanism analytical method is required, However, only a of the derivatization reaction is based, analogous few methods that can quantify more than two to the reaction (8), ona sing-opening reac- metabolites simultaneously have been reported, _ tion of the pyridine substructure, starting with an and these generally require the use of electrophilic attack on the pyridine nitrogen, If ly labeled nicotine Barlow er af. de- this is true, only those metabolites that scribed a pre-column derivatization method an intact pyridine ring and bear no substituent at yielding acid (DET- the nitrogen atom can undergo this reaction. This BA) derivatives, which can be separated by high- is the case for the majority of the known nicotine performance liquid chromatography (HPLC), metabolites with few exception, eg. cotinine-N- ‘They were able to determine nicotine and coti- oxide and the previously reported Neglucuro- nine. In addition, they observed five metabolites _nides (9). that they could not identify, Parviainen and Bar- This paper describes the extension of the HPLC assay to detect and quamtty all those me- tabolites in the urine of humans and laboratory g Corresponding author. animals that form DETBA derivatives, As the 3 g $06.00 ©1993 Elsevier Science Publishers All ighiseeseried 3" ]	[ [ 56, 82, 657, 887 ] ]	6
754	1,000	questionnaire	[ "ra", "‘T-127", "032387/1", "cigarettes", "Hello,", "I'm", "of", ".", "We", "are", "conducting", "a", "brief", "survey", "on", "cigarettes", "and", "would", "like", "to", "include", "your", "opinions.", "1.", "First,", "is", "there", "anyone", "Living", "in", "your", "household", "who", "is", "enployed", "in", "the", "sale,", "manufacture", "or", "distribution", "of", "tobacco", "products,", "or", "in", "market", "research,", "or", "advertising?", "Yes", "(TERMINATE)", "No", "2.", "Is", "there", "a", "person", "living", "in", "your", "home", "between", "the", "ages", "of", "21", "and", "59", "who", "snokes", "at", "least", "10", "cigarettes", "per", "day?", "ves", "No.", "(TERMINATE)", "3.", "May", "T", "speak", "to", "that", "person?", "(IP", "NOT", "AVAILABLE,", "MAKE", "APPOINTMENT", "70", "CALL", "LATER.", "SAVE", "SCREENER.", "GET", "NAME", "AND" ]	[ [ 86, 97, 89, 101 ], [ 620, 92, 659, 102 ], [ 597, 106, 659, 117 ], [ 332, 188, 411, 199 ], [ 140, 243, 185, 255 ], [ 197, 243, 219, 253 ], [ 377, 239, 402, 260 ], [ 565, 250, 568, 253 ], [ 586, 244, 602, 253 ], [ 611, 246, 634, 253 ], [ 140, 264, 218, 276 ], [ 227, 267, 234, 274 ], [ 244, 264, 283, 274 ], [ 292, 267, 339, 276 ], [ 347, 267, 362, 274 ], [ 372, 264, 450, 276 ], [ 459, 264, 482, 274 ], [ 490, 264, 530, 274 ], [ 540, 264, 570, 274 ], [ 580, 265, 594, 274 ], [ 141, 285, 195, 294 ], [ 204, 287, 234, 296 ], [ 243, 285, 312, 297 ], [ 140, 325, 152, 334 ], [ 171, 325, 216, 336 ], [ 228, 325, 242, 335 ], [ 252, 326, 290, 335 ], [ 299, 328, 346, 337 ], [ 356, 325, 401, 337 ], [ 411, 328, 425, 335 ], [ 435, 328, 465, 337 ], [ 474, 325, 545, 335 ], [ 554, 325, 578, 334 ], [ 587, 325, 601, 334 ], [ 171, 346, 234, 357 ], [ 244, 345, 258, 354 ], [ 268, 346, 290, 355 ], [ 300, 346, 335, 356 ], [ 346, 346, 433, 355 ], [ 442, 348, 457, 355 ], [ 466, 345, 561, 355 ], [ 570, 345, 585, 354 ], [ 172, 366, 226, 375 ], [ 235, 366, 303, 377 ], [ 314, 368, 329, 375 ], [ 339, 368, 353, 375 ], [ 362, 366, 409, 375 ], [ 418, 366, 487, 376 ], [ 498, 368, 513, 375 ], [ 522, 365, 616, 377 ], [ 418, 407, 440, 415 ], [ 452, 406, 534, 416 ], [ 417, 427, 433, 435 ], [ 139, 466, 151, 476 ], [ 171, 468, 185, 476 ], [ 195, 467, 233, 476 ], [ 242, 469, 248, 476 ], [ 258, 469, 305, 478 ], [ 314, 467, 360, 479 ], [ 370, 469, 385, 476 ], [ 394, 469, 424, 479 ], [ 433, 467, 464, 476 ], [ 473, 467, 528, 476 ], [ 538, 467, 560, 476 ], [ 570, 469, 600, 479 ], [ 610, 466, 624, 476 ], [ 171, 487, 184, 496 ], [ 194, 487, 217, 496 ], [ 227, 487, 240, 496 ], [ 249, 487, 273, 496 ], [ 282, 487, 328, 496 ], [ 338, 488, 352, 496 ], [ 362, 487, 400, 496 ], [ 410, 487, 424, 496 ], [ 433, 488, 512, 498 ], [ 521, 490, 544, 498 ], [ 553, 487, 584, 498 ], [ 417, 528, 439, 536 ], [ 417, 548, 432, 556 ], [ 443, 547, 525, 557 ], [ 139, 587, 151, 596 ], [ 169, 588, 193, 599 ], [ 202, 588, 208, 596 ], [ 217, 587, 256, 599 ], [ 266, 588, 280, 596 ], [ 290, 587, 320, 596 ], [ 329, 588, 383, 599 ], [ 171, 627, 192, 638 ], [ 201, 628, 224, 637 ], [ 232, 629, 309, 639 ], [ 320, 629, 352, 637 ], [ 360, 629, 447, 637 ], [ 177, 648, 192, 657 ], [ 201, 648, 232, 657 ], [ 241, 649, 286, 657 ], [ 304, 649, 336, 657 ], [ 345, 649, 413, 657 ], [ 432, 649, 455, 658 ], [ 177, 669, 208, 677 ], [ 216, 669, 240, 677 ] ]	[ "ra ‘T-127 032387/1 cigarettes Hello, I'm of . We are conducting a brief survey on cigarettes and would like to include your opinions. 1. First, is there anyone Living in your household who is enployed in the sale, manufacture or distribution of tobacco products, or in market research, or advertising? Yes (TERMINATE) No 2. Is there a person living in your home between the ages of 21 and 59 who snokes at least 10 cigarettes per day? ves No. (TERMINATE) 3. May T speak to that person? (IP NOT AVAILABLE, MAKE APPOINTMENT 70 CALL LATER. SAVE SCREENER. GET NAME AND TELEPHONE NUMBER.) 4. Is your regular brand of cigarettes a filter or non-filter 8 cigarette? Filter g Non-filter & 8 5. Is your regular brand of cigarettes menthol or non-menthol? Non-menthol" ]	[ [ 86, 92, 659, 876 ] ]	13
1,000	754	budget	[ "ST;-", "AuG", "9 IScd", "THE", "TOBACCO", "INSTITUTE", "STATE ACTIVITIES", "CONTRIBUTION /HONORARIUM", "REQUEST", "Contribuci", "CHECK ONE :", "Honorariun:", "771728", "1.D", "Soc", "Sec . #", "RECIPIENT", "INFOREMATION", "Fr4z", "Nane", "Robert", "Scate:", "3088", "Pico", "Incurbent", "(Yin) :", "Adatess", "Party (DIR/O} :", "Address", "Suite", "200", "Eest/zIP:", "Indivldual/Group", "Carlsbad", "CA 92008", "The", "Honorabl -", "Salutation:", "Assenblyman Frazee", "RUNNINGFOR", "(CHECK", "HORE", "TAAN", "ONE", "I4 EACH", "COLUHN)", "(2)", "(3)", "LOCAL", "LEGISLATURE :", "UPPER", "STATE :", "EXECUTIVE:", "LOWER :", "CITY", "COUNTY:", "(IF APPLICABLE)", "CURRENT", "OFFICE", "(1}", "(2)", "LOCAL", "LEGISLATURE :", "UPPER", "STATE", "EXECUTIVE :", "LOWER", "CITY", "COUNTY :", "COMHITTEE", "(CHEcR AS TAMY As", "ASS GNFENTS", "APPLY )", "Finance:", "Healch:", "Rules :", "Judiciary:", "(exp", "Bus iness", "Other", "l2in)", "CHECKINFORATTON", "Amounc", "(S):", "O0O,", "Needed", "DY :", "Imnediately", "Payable", "Friends", "Bob", "Frezee", "Cost", "Center:", "Address", "1228", "Screet", "Account", "Address", "Suiee", "City/ST/ZIF:", "Sacrarenco", "CA 95814", "Honorarium details:", "Ocher", "comments", "APPROVAL", "Legislative", "Counsel:", "A-K", "fssocades", "John", "Regional", "\"mnrroz", "Sector V.P.", "TCALO414311" ]	[ [ 505, 77, 549, 93 ], [ 563, 77, 595, 97 ], [ 605, 77, 647, 95 ], [ 287, 141, 313, 155 ], [ 317, 141, 377, 155 ], [ 381, 141, 453, 155 ], [ 177, 153, 305, 169 ], [ 311, 153, 493, 169 ], [ 497, 155, 555, 169 ], [ 200, 178, 281, 196 ], [ 93, 179, 173, 193 ], [ 435, 179, 521, 195 ], [ 271, 189, 321, 207 ], [ 203, 193, 229, 207 ], [ 435, 193, 461, 207 ], [ 473, 193, 513, 207 ], [ 93, 217, 167, 233 ], [ 172, 219, 258, 233 ], [ 195, 244, 223, 257 ], [ 93, 245, 127, 259 ], [ 255, 245, 305, 259 ], [ 435, 245, 483, 259 ], [ 195, 257, 229, 271 ], [ 265, 257, 297, 271 ], [ 435, 257, 509, 271 ], [ 515, 257, 561, 273 ], [ 94, 260, 148, 268 ], [ 435, 269, 545, 285 ], [ 93, 271, 149, 285 ], [ 193, 271, 235, 285 ], [ 241, 271, 267, 285 ], [ 108, 282, 190, 312 ], [ 435, 282, 561, 299 ], [ 195, 283, 259, 299 ], [ 271, 283, 337, 299 ], [ 193, 297, 221, 311 ], [ 225, 297, 289, 311 ], [ 93, 309, 181, 323 ], [ 193, 309, 337, 325 ], [ 93, 335, 183, 349 ], [ 189, 335, 237, 349 ], [ 263, 335, 299, 349 ], [ 303, 335, 337, 349 ], [ 341, 335, 369, 349 ], [ 373, 335, 431, 349 ], [ 435, 335, 491, 349 ], [ 319, 361, 343, 375 ], [ 497, 361, 521, 375 ], [ 123, 373, 167, 387 ], [ 279, 373, 375, 389 ], [ 489, 373, 531, 387 ], [ 123, 387, 173, 401 ], [ 279, 387, 359, 401 ], [ 487, 387, 537, 401 ], [ 489, 399, 523, 413 ], [ 489, 413, 545, 427 ], [ 211, 435, 327, 453 ], [ 93, 437, 151, 451 ], [ 155, 439, 205, 453 ], [ 171, 463, 197, 479 ], [ 319, 465, 343, 479 ], [ 123, 477, 167, 491 ], [ 279, 477, 375, 491 ], [ 489, 477, 531, 491 ], [ 123, 489, 167, 503 ], [ 279, 489, 359, 503 ], [ 487, 489, 531, 503 ], [ 489, 503, 523, 515 ], [ 489, 515, 545, 529 ], [ 93, 539, 167, 555 ], [ 265, 539, 399, 555 ], [ 171, 541, 259, 555 ], [ 403, 541, 451, 555 ], [ 123, 567, 189, 581 ], [ 279, 567, 335, 581 ], [ 489, 567, 537, 581 ], [ 122, 577, 203, 595 ], [ 591, 578, 621, 594 ], [ 387, 579, 453, 593 ], [ 543, 579, 585, 593 ], [ 619, 579, 661, 593 ], [ 93, 604, 228, 619 ], [ 279, 605, 329, 619 ], [ 335, 605, 367, 621 ], [ 395, 605, 423, 619 ], [ 543, 605, 593, 619 ], [ 597, 607, 621, 621 ], [ 93, 619, 181, 633 ], [ 95, 643, 151, 659 ], [ 217, 643, 273, 657 ], [ 301, 643, 329, 657 ], [ 333, 643, 383, 657 ], [ 473, 643, 507, 657 ], [ 511, 643, 565, 655 ], [ 92, 655, 151, 672 ], [ 217, 655, 253, 671 ], [ 271, 657, 321, 671 ], [ 474, 658, 528, 666 ], [ 93, 669, 151, 683 ], [ 217, 669, 259, 683 ], [ 93, 681, 189, 697 ], [ 217, 681, 299, 695 ], [ 311, 681, 375, 697 ], [ 93, 707, 243, 723 ], [ 93, 721, 135, 735 ], [ 141, 723, 205, 735 ], [ 93, 745, 159, 759 ], [ 93, 771, 183, 787 ], [ 187, 771, 251, 785 ], [ 263, 771, 291, 785 ], [ 296, 774, 372, 782 ], [ 263, 783, 299, 799 ], [ 93, 785, 159, 801 ], [ 258, 785, 367, 812 ], [ 93, 795, 181, 811 ], [ 491, 917, 589, 937 ] ]	[ "ST;- AuG 9 IScd", "THE TOBACCO INSTITUTE STATE ACTIVITIES CONTRIBUTION /HONORARIUM REQUEST", "Contribuci 1.D 771728", "CHECK ONE :", "Honorariun: Soc Sec . #", "RECIPIENT INFOREMATION", "Nane Fr4z Robert Adatess 3088 Pico Address Suite 200 Carlsbad CA 92008 Eest/zIP: The Honorabl - Salutation: Assenblyman Frazee", "Scate: Incurbent (Yin) : Party (DIR/O} : Indivldual/Group", "RUNNINGFOR (CHECK", "HORE TAAN ONE I4 EACH COLUHN)", "(2)", "(3) UPPER LOWER : CITY COUNTY:", "LOCAL STATE :", "LEGISLATURE : EXECUTIVE:", "CURRENT OFFICE (IF APPLICABLE)", "(1} LOCAL STATE", "(2)", "LEGISLATURE : EXECUTIVE :", "UPPER LOWER CITY COUNTY :", "COMHITTEE ASS GNFENTS (CHEcR AS TAMY As APPLY )", "Finance: Judiciary:", "Healch:", "Rules : Other (exp l2in)", "Bus iness", "CHECKINFORATTON Imnediately", "Amounc (S):", "O0O,", "Needed DY :", "Payable Address Address City/ST/ZIF:", "Friends Bob Frezee 1228 Screet Suiee Sacrarenco CA 95814", "Cost Center: Account", "Honorarium details: Ocher comments", "APPROVAL", "Legislative Counsel: A-K fssocades Regional John Sector V.P. \"mnrroz", "TCALO414311" ]	[ [ 505, 77, 647, 97 ], [ 177, 141, 555, 169 ], [ 200, 178, 321, 207 ], [ 93, 179, 173, 193 ], [ 435, 179, 521, 207 ], [ 93, 217, 258, 233 ], [ 93, 244, 337, 325 ], [ 435, 245, 561, 299 ], [ 93, 335, 237, 349 ], [ 263, 335, 491, 349 ], [ 319, 361, 343, 375 ], [ 487, 361, 545, 427 ], [ 123, 373, 173, 401 ], [ 279, 373, 375, 401 ], [ 93, 435, 327, 453 ], [ 123, 463, 197, 503 ], [ 319, 465, 343, 479 ], [ 279, 477, 375, 503 ], [ 487, 477, 545, 529 ], [ 93, 539, 451, 555 ], [ 122, 567, 203, 595 ], [ 279, 567, 335, 581 ], [ 489, 567, 661, 594 ], [ 387, 579, 453, 593 ], [ 93, 604, 228, 633 ], [ 279, 605, 367, 621 ], [ 395, 605, 423, 619 ], [ 543, 605, 621, 621 ], [ 92, 643, 189, 697 ], [ 217, 643, 383, 697 ], [ 473, 643, 565, 666 ], [ 93, 707, 243, 735 ], [ 93, 745, 159, 759 ], [ 93, 771, 372, 822 ], [ 491, 917, 589, 937 ] ]	10
762	1,000	form	[ "wy", "RESEARCH", "&", "BROWN", "&", "WILLIAMSON", "DEVELOPMENT", "NONMENTHOL", "INTERNAL", "PANEL", "SENSORY", "(paired", "Dtferencey", "Oud", "lo", "24-78", "NAME", "DATE", "SAMPLE", "vs.", "‘SAMPLE", "Impact:", "fo.", "(2)", "Fal", "BODY:", "ar", "we", "AMOUNT", "OF", "5G)", "@", "Vere", "HO)", "ToBacco", "Tst:", "4", ":", "BETTER", "ry", "(0)", "TOBACCO", "TST:", "ae", "\|", "orrraste:", "fig", "4", "o", "\|", "HARD", "TO.", "(2)", "10", "(2)", "‘Oe", "DRAW.", "ae", "ea", "ae", "ee", "PREFERENCE", "(2)", "()", "440007623", "PRODUCED", "FROM", "B&W", "WEB", "SITE" ]	[ [ 102, 75, 168, 111 ], [ 284, 87, 367, 109 ], [ 373, 91, 382, 101 ], [ 58, 115, 107, 125 ], [ 113, 117, 123, 124 ], [ 128, 115, 213, 125 ], [ 287, 103, 389, 133 ], [ 485, 93, 595, 133 ], [ 245, 110, 310, 153 ], [ 313, 122, 360, 149 ], [ 362, 110, 431, 153 ], [ 481, 127, 525, 140 ], [ 530, 127, 600, 139 ], [ 119, 182, 179, 212 ], [ 431, 178, 455, 225 ], [ 462, 188, 533, 213 ], [ 142, 202, 176, 234 ], [ 475, 215, 507, 224 ], [ 233, 268, 284, 290 ], [ 390, 268, 412, 289 ], [ 524, 271, 575, 281 ], [ 40, 329, 86, 359 ], [ 144, 333, 217, 357 ], [ 519, 341, 533, 352 ], [ 140, 376, 160, 396 ], [ 39, 424, 77, 453 ], [ 446, 453, 510, 481 ], [ 590, 452, 658, 472 ], [ 39, 466, 92, 498 ], [ 93, 466, 113, 498 ], [ 139, 478, 156, 494 ], [ 227, 478, 241, 489 ], [ 458, 474, 493, 491 ], [ 585, 477, 607, 489 ], [ 39, 491, 100, 501 ], [ 104, 492, 131, 501 ], [ 588, 499, 590, 501 ], [ 654, 495, 661, 504 ], [ 39, 527, 87, 556 ], [ 295, 537, 316, 552 ], [ 365, 530, 387, 559 ], [ 38, 541, 98, 573 ], [ 104, 541, 127, 573 ], [ 340, 554, 359, 563 ], [ 498, 553, 508, 562 ], [ 38, 598, 109, 607 ], [ 144, 593, 156, 614 ], [ 293, 597, 299, 609 ], [ 372, 599, 386, 609 ], [ 390, 580, 417, 619 ], [ 38, 635, 69, 663 ], [ 77, 635, 97, 663 ], [ 226, 643, 241, 655 ], [ 372, 644, 386, 655 ], [ 517, 644, 531, 655 ], [ 584, 638, 621, 658 ], [ 27, 641, 81, 678 ], [ 479, 643, 507, 680 ], [ 341, 675, 361, 691 ], [ 440, 677, 468, 686 ], [ 440, 675, 663, 716 ], [ 37, 704, 120, 713 ], [ 226, 705, 240, 716 ], [ 371, 705, 386, 716 ], [ 4, 955, 78, 964 ], [ 2, 971, 68, 980 ], [ 82, 971, 115, 980 ], [ 126, 971, 151, 980 ], [ 161, 971, 185, 980 ], [ 197, 971, 230, 980 ] ]	[ "wy RESEARCH & BROWN & WILLIAMSON DEVELOPMENT NONMENTHOL INTERNAL PANEL SENSORY (paired Dtferencey Oud lo 24-78 NAME DATE SAMPLE vs. ‘SAMPLE Impact: fo. (2) Fal BODY: ar we AMOUNT OF 5G) @ Vere HO) ToBacco Tst: 4 : BETTER ry (0) TOBACCO TST: ae \| orrraste: fig 4 o \| HARD TO. (2) 10 (2) ‘Oe DRAW. ae ea ae ee PREFERENCE (2) () 440007623 PRODUCED FROM B&W WEB SITE" ]	[ [ 2, 75, 663, 980 ] ]	1
754	1,000	specification	[ "ASIC", "WEIGHT", "SPECLFLCATION", "Loursvrite", "EFFECTIVE", "DATE:", "09/29/1995", "GENERALS", "NON-FILTER", "KS", "REGULAR", "SP", "STANDARD", "PRODUCTION", "BRAND", "CODE-06990", "(STD)", "PHYSICAL", "PARAMETERS", "ROD", "LENGTH:", "1", "PAPER", "KIDTH", "+", "27.00", "CIRCUMFERENCE", "24.80", "CALCULATED", "VOLUME", "cusic", "HM", "CALCULATED", "DENSITY", "26.2812", "TARGETS", "PACK", "v", ":", "13.00", "xm", "TARGET", "3.20", "om", "RANGE", "FROM", "2.80", "TO", "CONE", "MEEK", "RANGE:", "FROM", "3.10", "(EIGHT", "WEEK", "FILLER", "9962027", "‘CALCULATED", "WEIGHT:", "2.1965", "Les.", "PAPER", "AND.", "ADHESIVE", "werGHT", "TOTAL", "Less", "PLUG", "‘GRAMS", "REASON", "FOR", "CHANGE", "SPECIFICATION", "UPDATED", "To", "REFLECT", "UPDATED", "PAPER", "2", "AND", "WEIGHT", "AND/OR", "TIPPING", "AND", "ADHESIVE", "=", "WEIGHT,", "TOTAL", "LESS", "PLUG", "WEIGHT", "CHANGED.", "OK", "TO", "3", "1", "MDX", "CIGARETTES", "PREPARED", "BY" ]	[ [ 314, 97, 343, 106 ], [ 351, 98, 387, 106 ], [ 394, 98, 473, 106 ], [ 85, 99, 153, 127 ], [ 511, 112, 564, 119 ], [ 572, 112, 600, 119 ], [ 616, 113, 675, 120 ], [ 93, 124, 141, 131 ], [ 149, 124, 209, 131 ], [ 216, 124, 227, 131 ], [ 235, 124, 276, 131 ], [ 284, 125, 295, 131 ], [ 511, 126, 559, 133 ], [ 566, 126, 627, 133 ], [ 94, 137, 123, 144 ], [ 130, 137, 190, 144 ], [ 199, 138, 227, 144 ], [ 325, 169, 380, 197 ], [ 383, 169, 447, 197 ], [ 179, 206, 196, 213 ], [ 204, 206, 275, 213 ], [ 480, 207, 491, 214 ], [ 191, 219, 220, 227 ], [ 228, 219, 257, 227 ], [ 273, 225, 275, 227 ], [ 339, 220, 367, 227 ], [ 121, 221, 208, 249 ], [ 339, 234, 367, 240 ], [ 130, 247, 190, 254 ], [ 198, 247, 233, 254 ], [ 443, 248, 472, 254 ], [ 480, 248, 490, 254 ], [ 130, 260, 190, 267 ], [ 197, 260, 239, 267 ], [ 326, 248, 367, 276 ], [ 356, 301, 411, 309 ], [ 129, 327, 152, 334 ], [ 178, 328, 183, 334 ], [ 272, 330, 274, 332 ], [ 339, 328, 367, 335 ], [ 461, 328, 490, 335 ], [ 184, 354, 220, 361 ], [ 335, 343, 366, 371 ], [ 460, 355, 472, 362 ], [ 175, 356, 213, 384 ], [ 313, 368, 337, 375 ], [ 350, 369, 373, 375 ], [ 387, 369, 398, 375 ], [ 523, 369, 545, 376 ], [ 552, 369, 575, 376 ], [ 175, 370, 213, 398 ], [ 313, 382, 337, 389 ], [ 350, 382, 373, 389 ], [ 523, 383, 558, 389 ], [ 565, 383, 588, 390 ], [ 128, 449, 164, 456 ], [ 325, 437, 366, 465 ], [ 165, 462, 226, 469 ], [ 233, 463, 269, 469 ], [ 331, 463, 366, 469 ], [ 430, 463, 451, 470 ], [ 128, 476, 158, 483 ], [ 165, 476, 183, 483 ], [ 190, 476, 238, 483 ], [ 153, 489, 188, 496 ], [ 128, 503, 157, 509 ], [ 165, 503, 189, 509 ], [ 196, 503, 219, 509 ], [ 459, 504, 489, 510 ], [ 127, 812, 163, 819 ], [ 170, 812, 187, 819 ], [ 195, 812, 230, 819 ], [ 281, 813, 359, 820 ], [ 366, 813, 408, 820 ], [ 415, 813, 427, 820 ], [ 434, 814, 475, 820 ], [ 483, 814, 524, 821 ], [ 532, 814, 561, 821 ], [ 669, 812, 679, 824 ], [ 280, 827, 298, 833 ], [ 360, 827, 396, 834 ], [ 403, 827, 438, 834 ], [ 446, 827, 488, 834 ], [ 495, 827, 512, 834 ], [ 519, 827, 567, 834 ], [ 670, 825, 679, 838 ], [ 280, 840, 315, 847 ], [ 336, 840, 364, 847 ], [ 373, 840, 395, 847 ], [ 403, 841, 426, 847 ], [ 433, 841, 469, 847 ], [ 476, 841, 518, 848 ], [ 538, 841, 548, 848 ], [ 556, 841, 567, 848 ], [ 670, 839, 680, 852 ], [ 270, 856, 271, 860 ], [ 280, 853, 297, 860 ], [ 360, 854, 420, 861 ], [ 126, 880, 174, 887 ], [ 182, 880, 192, 887 ] ]	[ "ASIC WEIGHT SPECLFLCATION Loursvrite EFFECTIVE DATE: 09/29/1995 GENERALS NON-FILTER KS REGULAR SP STANDARD PRODUCTION BRAND CODE-06990 (STD) PHYSICAL PARAMETERS ROD LENGTH: 1 PAPER KIDTH + 27.00 CIRCUMFERENCE 24.80 CALCULATED VOLUME cusic HM CALCULATED DENSITY 26.2812 TARGETS PACK v : 13.00 xm TARGET 3.20 om RANGE FROM 2.80 TO CONE MEEK RANGE: FROM 3.10 (EIGHT WEEK FILLER 9962027 ‘CALCULATED WEIGHT: 2.1965 Les. PAPER AND. ADHESIVE werGHT TOTAL Less PLUG ‘GRAMS REASON FOR CHANGE SPECIFICATION UPDATED To REFLECT UPDATED PAPER 2 AND WEIGHT AND/OR TIPPING AND ADHESIVE = WEIGHT, TOTAL LESS PLUG WEIGHT CHANGED. OK TO 3 1 MDX CIGARETTES PREPARED BY Kev. PRINTING DATE PREPARATION DATE 2 9/2/95 APPROVED BY. SUPERCEDES SPECIFICATION DATED: 4/27/95" ]	[ [ 85, 97, 680, 928 ] ]	7
754	1,000	email	[ "2077981575", "yp", "Page", "1", "as", "4", ":", "Note", "for", "Mahon,", "Jean", "yp", "ie", "4", "A", "From", "Mulderig,", "John", "ye", "w", "Date:", "Fri,", "Jan", "3,", "1997", "6:43", "AM", "\\", "iP", "Subject:", "RE:", "Records", "os", "Se", "J", "To:", "Mahon,", "Jean;", "Purcell,", "Clare", "ti", "\\A", "aw!", "a", "ce:", "King,", "Valerie", "ak", "¥", "Based", "on", "your", "brief", "description,", "I", "end", "to", "doubt", "that", "any", "of", "the", "materials", "have", "any", "value", "to", "in", "the", "role", "she", "now", "plays", "and", "do", "not", "see", "much", "purpose", "in", "moving", "the", "records", "to", "Jean,", "You", "and", "Clare", "can", "discuss", "and", "determine", "if", "they", "have", "vaiue", "to", "Jean's", "position", "in" ]	[ [ 322, 115, 412, 143 ], [ 604, 120, 621, 147 ], [ 639, 126, 667, 136 ], [ 679, 126, 682, 134 ], [ 20, 140, 64, 154 ], [ 538, 143, 541, 148 ], [ 21, 163, 24, 166 ], [ 121, 156, 145, 166 ], [ 150, 156, 164, 166 ], [ 168, 146, 206, 174 ], [ 211, 156, 235, 167 ], [ 517, 150, 528, 169 ], [ 552, 147, 572, 166 ], [ 404, 185, 407, 188 ], [ 515, 170, 529, 195 ], [ 42, 182, 77, 212 ], [ 121, 191, 176, 203 ], [ 181, 191, 207, 201 ], [ 432, 179, 461, 222 ], [ 492, 185, 503, 198 ], [ 42, 208, 78, 236 ], [ 121, 215, 140, 227 ], [ 145, 215, 163, 225 ], [ 168, 215, 178, 227 ], [ 184, 215, 208, 225 ], [ 210, 207, 238, 235 ], [ 242, 207, 264, 235 ], [ 373, 204, 376, 224 ], [ 535, 209, 555, 230 ], [ 51, 243, 95, 253 ], [ 122, 239, 142, 250 ], [ 147, 239, 192, 250 ], [ 382, 241, 406, 268 ], [ 468, 233, 487, 263 ], [ 555, 224, 577, 270 ], [ 42, 254, 67, 284 ], [ 122, 264, 164, 276 ], [ 168, 264, 196, 276 ], [ 198, 254, 243, 284 ], [ 247, 254, 276, 284 ], [ 358, 246, 380, 285 ], [ 408, 244, 438, 282 ], [ 450, 273, 459, 281 ], [ 481, 252, 506, 293 ], [ 51, 278, 68, 306 ], [ 122, 288, 152, 301 ], [ 156, 288, 196, 298 ], [ 386, 275, 410, 306 ], [ 436, 279, 452, 307 ], [ 122, 321, 156, 331 ], [ 159, 324, 173, 331 ], [ 177, 324, 202, 334 ], [ 206, 321, 233, 331 ], [ 236, 321, 299, 334 ], [ 303, 321, 307, 331 ], [ 311, 321, 334, 331 ], [ 338, 323, 348, 331 ], [ 352, 321, 383, 331 ], [ 387, 321, 407, 331 ], [ 411, 324, 430, 334 ], [ 434, 321, 446, 331 ], [ 449, 321, 465, 331 ], [ 470, 321, 519, 331 ], [ 523, 321, 548, 331 ], [ 553, 324, 572, 334 ], [ 576, 321, 606, 331 ], [ 610, 323, 620, 331 ], [ 652, 324, 662, 331 ], [ 122, 335, 138, 345 ], [ 143, 335, 164, 345 ], [ 168, 335, 186, 345 ], [ 190, 338, 214, 345 ], [ 218, 335, 246, 347 ], [ 250, 335, 270, 345 ], [ 274, 335, 287, 345 ], [ 291, 337, 308, 345 ], [ 312, 338, 329, 345 ], [ 333, 335, 363, 345 ], [ 367, 338, 410, 347 ], [ 415, 338, 424, 345 ], [ 429, 338, 470, 347 ], [ 474, 335, 490, 345 ], [ 495, 335, 535, 345 ], [ 539, 337, 549, 345 ], [ 553, 335, 577, 345 ], [ 586, 335, 608, 345 ], [ 613, 335, 632, 345 ], [ 636, 335, 666, 345 ], [ 122, 352, 141, 359 ], [ 145, 349, 185, 359 ], [ 189, 349, 208, 359 ], [ 213, 349, 268, 359 ], [ 272, 349, 281, 359 ], [ 284, 349, 305, 362 ], [ 311, 349, 336, 359 ], [ 341, 349, 370, 359 ], [ 374, 351, 384, 359 ], [ 388, 349, 420, 359 ], [ 424, 350, 468, 361 ], [ 472, 352, 482, 359 ] ]	[ "2077981575 yp Page 1 as 4 : Note for Mahon, Jean yp ie 4 A From Mulderig, John ye w Date: Fri, Jan 3, 1997 6:43 AM \\ iP Subject: RE: Records os Se J To: Mahon, Jean; Purcell, Clare ti \\A aw! a ce: King, Valerie ak ¥ Based on your brief description, I end to doubt that any of the materials have any value to in the role she now plays and do not see much purpose in moving the records to Jean, You and Clare can discuss and determine if they have vaiue to Jean's position in its present form. If the records do not have any present use, they should be evaluated for disposal suspension and if on disposal suspension, permanently retained as part of Clare's inactive files. Bill Lynch can assist in the evaluation, Tf not on disposal suspension, the records should be managed pursuant to applicable records retention schedules and procedures for records not on disposal suspension, John" ]	[ [ 20, 115, 682, 442 ] ]	2
1,000	754	handwritten	[ "AuLLEL", "Zau", "Z", "Z1z L", "Zeez", "Lzz", "[L1", "LL4 Z", "Ezz", "Zz", "El", "2LLill z", "Zcusss", "ZiLLe'", "7a2", "1iLea&", "Zz", "7Z2", "ZUA", "Zis -DIEeE", "7udus", "4ze23", ":", "$51", "272 =", "82", "1" ]	[ [ 439, 600, 566, 637 ], [ 119, 603, 177, 639 ], [ 208, 604, 284, 634 ], [ 472, 628, 564, 658 ], [ 354, 636, 464, 688 ], [ 136, 638, 204, 662 ], [ 307, 641, 361, 661 ], [ 218, 642, 299, 662 ], [ 133, 659, 255, 721 ], [ 216, 660, 290, 690 ], [ 532, 662, 572, 686 ], [ 577, 695, 661, 711 ], [ 606, 712, 684, 738 ], [ 244, 716, 336, 742 ], [ 486, 716, 598, 744 ], [ 125, 720, 234, 749 ], [ 132, 744, 192, 770 ], [ 201, 749, 257, 769 ], [ 374, 761, 481, 797 ], [ 359, 789, 597, 832 ], [ 366, 814, 466, 858 ], [ 581, 818, 668, 848 ], [ 685, 819, 699, 857 ], [ 566, 846, 624, 872 ], [ 354, 848, 438, 876 ], [ 452, 848, 494, 874 ], [ 685, 863, 699, 901 ] ]	[ "Zau Z AuLLEL Lzz LL4 Z [L1 Z1z L Zeez Zz El Ezz 2LLill z 1iLea& ZiLLe' 7a2 Zcusss Zz 7Z2 ZUA Zis -DIEeE 7udus 4ze23 : 272 = 82 $51 1" ]	[ [ 119, 600, 699, 901 ] ]	3

754

1,000

questionnaire

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[ "MARKETVIEW RESEARCH GROUP, INC. #830801 Meer ose. Sute 108 en Jersey. 07020 January, 2001 7590201 840.5300 ONLINE AGE VERIFICATION ATTITUDE RESEARCH bea A consumer produets has selected you to in a suney about age yur and we would goat appre you woud take omen! of sony. his suey shoul ke han 10 minutes We know your time is and 0 thank you for completing the suvey before wil You ho a rondom rain tina Sony OVD player ‘To go toe simply folowing ink or copy an your browse. \"rank yu again faking the tne og us your opinions! Please be assured that you wil ol be asked to buy Trang tine so det fost ts You sponses Sincerely, PERSONAL INFORMATION presse provide the flewing before the the sey an tobe entered in te craig Frat Name Midi — LastName: cc sue cI Date of it Diversticense [7] Stat ap c— 3 Pr 3 8 8 tat have provided and am 21 years of geo ler O Yes" ]

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[ ": ‘ | SMOKING ANALYSIS i SAMPLE R-A011¢1) (#1213)-89 RUN DATE 1 BRAND 8Smm NE DATE RECEIVEN: 06/13/89 1 ¢ DATE PREPARED! 06/13/89 DATE SHOKED 06/14/89 i MEAN WEIGHT/100 4966 NO. OF CIG FER FAD - CONTROL? 5S PERCENT SELECTED ¢ FILTER 0 BUTT LENGTH (mn)? 2360 No. OF FADS Ps i REMARKS! Pe morsanses st) % REL 95% CONF No. i bev so LIMIT OES. i WEIGHT 0.491 00062-1428 0483 - 0-499 5 4 PRESSURE DROP | 228.1 18.31 8.03 220.6 - 235.725 | 5 TRY PART MAT ! 15.2 1.23 8.09 13.7 - 16.7 5 ie NICOTINE 0.87 0.038 4.42 0.82 - 0.92 5 fi CORRECTED PART MAT 14.3 4.19 12.9 - 15.8 8 CARBON HONOXIDE (ms/eis)? i 8.8 0.58 6652 98 5 i PUFF COUNT ¢ | a7 0.24 5.03 aa 5.0 s \\ XN \\ 8 & & x 8" ]

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5

754

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[ "Clinical and Molecular Techniques for Diagnosis and Monitoring of Prostatic Cancer C. S. FOSTER, MD, PHD, MRCPatH, AND P. D. ABEL, CuM FRCS Part2 of this ymposiam reviews of prostate in prostatic biopsy specimens and has evaluated the cancer apd other than conventional computer-based image systems currenly avai that rely either on specialized inscrumen- able for analyzing prostate cancer. That clearly The majority of such techniques already have been ad- puters for morphometric analysis with an evaluation of dressed opies inthis However, methods currently uvalable, with ther prob Contributions to the averall understanding of For exauiple, ifs image analysis system Consideration of features, crunpredictable nature, then the expense ofa dedicated ceed tt compauble software programs able To un on come mercially available appears to be the TISSUE MORPHOMETRY sisted. acquisition of morphometric data is laborious, these various aspects of prostae measurements of tumor volume provides an en- examined, Although hanced assessment of the of individual oF [tom autopsy material! other nave examined volumetric i biopsy Although there ig and have shown these sb to be important of NHK shee parler. her poten and ee ay prostatic resection, the ratiu of prostatic chippings con- P this approach shoal be adopted with cautious ining cancer to the wal number of chippings removed of the limitations of the numerical data ob- stage and volume.’ Recently, tis technique ta relative areas of cancer IMAGING TECHNIQUES resected prostatic chippings. x! Image phasiced the value of camputer-issisted morphometry Magnetic Reserance Imaging coupled with powerful data processing computer soft-etecuon of small and localized malignancies mare have renewed in morphologic provides the best opportunity for cure. To such grading systems and have shown these fo be a more accurate appraisal of te size, location, and extent and, hence, objective of obtaining of the primary disease iy uandatory. In this respect detailed data with which co predict the and cransrectal ultrasound burn prostate cancer In this symposium, (TRUS) of the prostate are approximately 60% accurate Dalton Hiss 1993) has aderessed| OF potentially greater valne magnetic resonance ine a ‘ar and Walach provide compelling evidence that while From the Departments of Histopathology and Surgery, Wlagnetic resonance imaging with current levels of res- School, UR, olution’ at 300 ym fapproximately 20 cell st ‘ics one snd repre to provides acceptable images that accurately enable the ‘MD, PhD, MRCPath, Department of Ehstopathology. Roval Post- location of small fesions, further refinement of resolu- Mea tion wll this toward the level of Up 1992 by WB, Sander Compan Furthermore, magoelic resonance a troscopie of issue components nd 305 50628402" ]

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6

762

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[ "610 BATTA GORI Franklin Institute Policy Analysis Center 1320 Fenwick Lane Silver Spring, MD 20910 (301) 585-8722 EXPERIENCE/BACKGROUND 0 Biology, toxicology, epidemiology, and management. © Played key roles in the successful passage of the 1970 Cancer Act and subsequent appropriations. Planned and managec research and intervention programs of national and international scope, establishing consensus priorities in cancer causation, prevention and control, and patient managenent. 0 Exerted national leadership in carcinogenesis research, methods and priorities of carcinogen testing, epidemiology. sncking and health, nutrition, ozone depletion and ultraviolet radiation, cost and benefit analysis of prevention policies, safety and carcinogen regulation. © Firsthand understanding of federal research and regulatory agencies, the budgetary and appropriations process, Congress and legislative operations, the diversity of motivation in private enterprise, academia, advocacy groups, and the pluralistic soctoeconomic reality. Extensive consulting experience with petrochemical and chemical industries, pharmaceutical manufacturers, cosmetic and food industries, and mining. © Direct multilingual contacts with parallel issues and organizations in Europe. Nurerous appearances at congressional hearings. Congressional contacts and familiarity with the lay and scientific media. 1" ]

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[ "ag We mvoce a - alls City _ ae ag 193, 5 Com & Company — 1427420 Louisville gun Be | eee SUSE (902) 5007375 DATE: October 5, 1979 = eae a ge. 3 Brown ee 2 L 4600 W, Hil St. | Kentucky 40202 aos | Glenda SO Hyatt | Se we ook “oferta an RENTAL | a “12 | Welt safelock stands 16}00 | 3] 1 -| extra castored stand i £] 1 lanp & | | “| trouperette ITI w/spare lamp az} 1 3/4\" VIR w/monitor on cart a aes 260}00 | 8 x 8 sereen Mike Ro vay i 24100 4 Impedence match box w/cables, mike, . j 71/00 | lel 43/04 | Bie “ORIGINAL | [APPROVED For | 7 jest ql | SEE SEY! [a as mms one ying be ee pn ey Se | uae veer De | the | Pie Sx oe ater PR | RECT oy pare PAR es SEE" ]

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11

1,000

754

email

[ "Tonyd", "From: Tuckcr;", "(LHC)", "To;ltlcrann, Palti F", "CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M,", "BCC:", "Primary Date: 4/23/1997 2.16.01 PM", "Last Modified Date: 1997-Dec-15 08.15.59", "Last Touched Date:", "Sent Date: 1997-Apr-23 13.31.0", "Received Datc: 1997-Apr-23 14.16.01", "Subject:", "Attachments:", "MRIAUDXLS", "My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs", "MRIAUDXLS", "3925 in MRIAUD XLS ]]", "8", "8", "RJR24041434", "70004 1403" ]

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[ "From: Tuckcr; Tonyd (LHC) To;ltlcrann, Palti F CC: Stcrling, Carol (LHC); Kendall, Suc (LHC); Williard, JoAn M, BCC: Primary Date: 4/23/1997 2.16.01 PM Last Modified Date: 1997-Dec-15 08.15.59 Last Touched Date: Sent Date: 1997-Apr-23 13.31.0 Received Datc: 1997-Apr-23 14.16.01 Subject:", "Attachments: MRIAUDXLS", "My mail is nOl coopcraling: This is thc sprcadshect with absolule numbcrs", "MRIAUDXLS 3925 in MRIAUD XLS ]]", "8 8", "RJR24041434 70004 1403" ]

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2

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news article

[ "‘the", "decision", "of", "the", "Aneriean", "Heart", "Association", "to", "Join", "tn", "educatloral", "campatene", "to", "discourage", "vas", "reported", "in", "and", "ty.", "the", "wire", "services.", "Sone", "stories", "a", "round-up", "of", "other", "recent.", "affecting", "the", "tobacco", "industry", "set", "S", "TRIBUNE", "The", "Words", "Get", "YORK", "nm", "New", "York,", "N.Y.", "I", ".", ".", "June", "9,", "1963", "rt", "Associz", "eart", "Association", "mokm,", "arnm.", "few", "York", "New", "York,", "June", "9,", "1963", "between", "cigarette", "smoking", "shoul", "be", "Heart", "Society", "Maps:", "none", "professions.”", "Henst", "Assocation,", "July,", "1960.", "Drive", "on", "Cigarettes", "er", "do", "Tiere", "of", "the.", "harmfut", "effects", "of", "cigarette", "smoking", "to", "warrant", "the", "By", "ALFRED", "F,", "ue", "ands", "and", "and" ]

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[ "‘the decision of the Aneriean Heart Association to Join tn educatloral campatene to discourage vas reported in and ty. the wire services. Sone stories a round-up of other recent. affecting the tobacco industry set S TRIBUNE The Words Get YORK nm New York, N.Y. I . . June 9, 1963 rt Associz eart Association mokm, arnm. few York New York, June 9, 1963 between cigarette smoking shoul be Heart Society Maps: none professions.” Henst Assocation, July, 1960. Drive on Cigarettes er do Tiere of the. harmfut effects of cigarette smoking to warrant the By ALFRED F, ue ands and and Amen set Ata ih, Chapter vung with the hee ta rng tb, hee smoking by the general public.” ‘emphasis on teen-agers. (Of attacks and strokes in Heat Asin, ytd. tcc ARG poard of directors An ad hoc committee of fone rm tear eae ae ee her aoe sed Toons ‘against smoking more strongly. Throwing out most of the groups.” The associa. NODS the Heart heath groups The associ’ urged Mat ete ge Mein ae, st ike rt Hae elution by the Association's board of directors meeting ‘The move marks the first More and larger longitudinal ted a aes etn ume utr AES Ja ) Shh Sa patie nan agency, naar, Reportedly, the AHA had been on the verge of launch- ded to wage a public campaign artery and other cartio. ing a public campaign against cigarette smoking following ‘on cone ‘a study in 1960 that showed that smokers are In 50 to 150 ‘A spokesman said that the , Possible of eter Sine at a a Sng rans pen rte ia gue ihe weft stout seareh Commitee sult fate ws a th Come cold Sl ea thas become available which contradicts or invalidates the the heart yesterday myocardial infarction and groupe ion? Officials of the Tobacco Industry Research Committee Jn 3960, the association of duration and in- spokesmen for the industry in the eontroversy— A report indicating that evidenc: censity of smoking on the risk Ses ore One, nd a ory SRS som acted ty and Gisease do not prove board reviews constituents of tobacco men have said in the past: \"Statistics never PE on the heart and blood vesse'= ‘killed anybody. ‘come shice £860, of animals and humans and ov ‘In the case of lung cancer it is usually assumed that Are Cited such disease processes ax ex: cigarette smoke may injure lung tissues, But a biological “No evidence has become perimental wR ‘Explanation for the link between heart ailments and since 2 Studien of patients tn our oir othe AA 1061 ne $B vn ANA Me on qos Se hoon ey ballets tat sucking Winger the Pe, Sis toe te A ac Hoe Sangeet an eins | to sue a tobacco company for the pert smoking ls Cigar ‘ortaty trom coronary N, Juan Bove ee ean Hints cies) he tune see sump on Wall Say sani Pity New York City Health SHEER, ees op james urged doctors to persuade patlents to stop smoking vessels theparms and legs seph T. Doyle of Albany and He warned that ony ebe of 15 lung cancer is now being saved and said: “If you (doctors! can that 0 Pre Tr on Cues Fu sea ter ee rst" ]

[ [ 55, 78, 730, 1000 ] ]

9

1,000

754

news article

[ "DRAFT", "AJS/ em", "3/24/81", "Proposed Response", "Press", "and", "Other", "Inquiries Regarding Publication by", "the", "Laboratory", "FTC", "FTC", "Test", "Results", "Carbon", "Yields", "Monoxide", "ofCigarettes", "a7", "Wih", "Lorillara", "the", "Tobacco", "statement urging", "Institute", "in interpreting", "caution", "the", "significance", "the Federal", "Commission baboratory", "Trade", "test", "results", "carbon monoxide", "yields of", "cigarettes", "ished", "publ_", "this", "week", "the", "Commission .", "Lorillard", "issuing", "spokesperson", "noted", "that", "chese", "test", "results", "the", "FTC", "nas attempted,", "without scientific", "proof", "to leave", "the", "impression", "that", "monoxide", "from", "carpon", "cigarette", "significant", "smoke", "represents", "threat", "human", "However ,", "health.", "Lorillard # rtodentative pointed", "Ere", "out", "that", "the", "relevant scientific literature", "this regard", "#t", "the great", "of scientific evidence", "inconclusive", "and", "body", "available", "indicates", "thc small", "the", "subject", "that", "amount", "monoxide generated", "carbon", "by cigarettes", "an insigni-", "ficant part of", "total", "the", "carbon", "monoxide", "the atmosphere", "L", "#4#" ]

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[ "AJS/ em DRAFT 3/24/81 Proposed Response Press and Other Inquiries Regarding Publication by the FTC FTC Laboratory Test Results Carbon Monoxide Yields ofCigarettes a7 Wih Lorillara the Tobacco Institute statement urging caution in interpreting the significance the Federal Trade Commission baboratory", "test results", "carbon monoxide yields of cigarettes", "publ_ ished this week", "the Commission .", "Lorillard", "issuing chese", "spokesperson noted that", "test results the FTC nas attempted, without scientific", "proof to leave the impression that carpon monoxide from", "cigarette smoke represents", "significant threat", "human", "health. However , Ere Lorillard # rtodentative pointed out", "that the relevant scientific literature this regard #t inconclusive and the great body of scientific evidence", "available", "the subject indicates that thc small amount", "carbon monoxide generated by cigarettes", "an insigni-", "ficant part of the total carbon monoxide", "the atmosphere", "L", "#4#" ]

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9

1,000

775

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0

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[ "septenber 17, 1988 MEMORANDUM TO FILE: The following are my comments and observations comparing The Anerican Tobacco Company to the Liggett Group. in the last year and one-half, The American Tobacco Company has made extraordinary strides forward that strengthenea its prospects for continuing its long record of increasing profits - . the sales trend has significantiy improved, with the first half of 1988 showing an increase in units and . the marketing and sales organizations have been increased and strengthened (particularly important with the increased in-store activity required due to greater competitive price and promotional activities) . export units have moved well above the 1 billion annual ea Durham factory was closed with a major reduction in very successful new products have been launched: BALL MALE Rel Filters and LIGHTS" ]

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15

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[ "3 Ak z 3 z i . be ve eT BE ‘ i SS oss : 2 BBS Rm 8 3 ne : “3 eee x Wee gg : ee Z : Ags ae eg H ge pes re Eos me id ita 5 «| P33 : | AE 0S 2 : i 52 (PAS 2 § } 83 Pas gi im BBS i | 24 is gis ° * i EF. me Ws pe BE Woe ge fe =, 3 Jey dy Pee 8 4 = H 22° 2-22 } is ae. é 8 : 22 8 2 Um Bigs NC | Bs |. #2 fH : i mee 5 po: gH ae 5 or Ti hy gia Py: og de. zo sk See «B83 82 2p Mee Ub Pap yy BR ce le ce : “24 BB 32 - HA : 2028719939" ]

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[ "B-192", "STATUS REPORT PROJECT No . MUNTHLY MANACEMCNT Migration Of Nicotine (MIGON PROJECT TITLE: DATE : 7/30/78 DUDGET 829 615 FROJECT DESCRIPTION: Vrinci) Taicel (act YC\" Tlc J\"gima onirclyC Uis OEOiCCt rulti Wucl Oeliiui /0 WMAlio\" AIROt' Lrom Hd VaF[ [IA Iralaeto 7i\"\" 7tmts otht Weci nrA W Ei\" Wl\"\" T Sdi I! Vni# CIl # MAALION Mlc weiv \"MHcF Jls. L (1in4\" Jed# 104nIn, FLc . Yili alue Tivi ML4IAT claczel# lcvecu Tnch L7,in @Gn Hlia Jid rumuclc dcLCrMine ({uai uer cxtnjclnm UOli Tuct\"cniyc Wicidi] Lt(Cl delerinfic MUttc OLa(JCLUrfM Jfter lolccu ercollicut", "YEARAZL78 MONTH", "1", "30", "24", "1 W", "PROJECT COM PONEnts Huran", "Euyi", "neteniLC IIC| Q1 ciu< MAiul OMLIEL", "Tal", "Jlcuei tnr Ael Cu Lrans [7t", "1,100 Total Hrs Budgeted", "758", "Date", "826 Hrs", "has been written on two experimental RL made Larson usinc A report lamina and stem: lamina ratio of 55:45 Smoking nicotine results ttgh taste panel results and leaf analyses the blend are included preference was noted for the experimental RL 70 8 available nicotine migrated filter paper treated with citric Up acid from filter paper treated with nicotine alkaloid: Tartaric acid produced migration nicotine alkaloid the acid treated paper No stoicometric relationship is readily apparent with these and other additives LAlmina Sue Ireland Sosnarn" ]

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[ "5 2 MT ion 2 House Democrats Offer a Compromise on Tobacco Regulati ‘By PHILIP ta na agency denn tout: vo ‘me Rosse props er Jay 26 — Two on OM nas wing 1 cis Tr eld pA EDA equi Cr DA are tes ne eu fom ee fn ceguaton of tobaceo, > have enaless ag nat” sd ote Peel ee 08 ves ecto la ere ie dca rei: go wig eae at ton weld en terror Tay nner ent tBu en ta ine Sent materi tis month, the agency as- Food and Drea, asserted ‘One guaranice in thd proposal is an addictive drug and regu. Polilcally dangerous question of power if the som ute ty 4 Ne see arama ey North Carolina Democeat who has debate comes as une Justice. Chacon and every tO cue cave nat ae resentative Ron Wyden of Oregon’ Dany executives lied to Congress or —— — Ro, en of se remand 0 me une revises Ha waa ena ana ae oe etic more a yearto he Deprtment| ew a 2h der chore re pring one lela sat from adverusing in e way intended} that the. was doce. iets | wat are ary oy st ye ested FT al a Re fear thatthe tobacco companies wil | could use the treat of sch ‘Wyden sad today that he | rake concessions satay ett a | iy\" ay | wae om Fite tobacco, “That's what Keeps the | Proposal the right thing in this proposal,” he |. study by the White House, wi | 6 2 by te tiated Set mang ‘Administration could avold nasty | marketing of Het ver would be done to Rose said the tobacco industry | ting che most effective messages many te] malorky in ina, single, am ‘here are licking their chops for that | » ‘one. They want to go head-to-head Some elements of the campaign s ea Nonetheless, Mr. Rose said that} chines and improving enforcement g “while both sides might have trouble } Gf laws that bar sales to minors. It 8 ‘with his plan, it would be worthwhile } would also include educational cam- g i es mapa stow eat] le so, tt and the tobacco from adversing to be et" ]

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9

762

1,000

memo

[ "DEA", "THE", "Memorandum", "AMERICAN", "TOBACCO,", "COMPANY,", "we", "Mr.", "E.", "C.", "Wortham", "oye", "9/17/92", "tn", "Glock,", "Leaf", "services", "Nenager", "ond’", "purley", "strips", "~", "1992", "&", "1992", "erope", "of", "serine", "ko.", "6379", "grades", "ray", "nave", "Ene", "potential", "fer", "in", "ou", "™~", "ge", "0211872" ]

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[ "DEA THE Memorandum AMERICAN TOBACCO, COMPANY, we Mr. E. C. Wortham oye 9/17/92 tn Glock, Leaf services Nenager ond’ purley strips ~ 1992 & 1992 erope of serine ko. 6379 grades ray nave Ene potential fer in ou ™~ ge 0211872" ]

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754

1,000

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[ "From: Cole, Ron W. To: Ainsworth, W.E. (Gene); Alan Calhoun; Anne Miller; Barbara Goho; Beverly Paszkowski; Brenda Matthews; Bryan Snipes; Carole Crosslin; Carolyn Brinkley; ‘Christopher Garland; Darryl Marsch; David Howard; David Powers; Delise LeBlanc; Denise Santos; Dianne Neal; Donald Foreman; Ellen Merritt; Frank Lester; Frank Skinner; Geni Coulter; Glenda Evans; Glenda Goodman; Guy Blynn; H. Bert Gomez; Harvey Freeman; Henry Stokes; Jackie Hemric; Jan Fulton Smith: Jean Lowstetter; Jerry MacFarland; Joan Rutledge; Joc Murray; John Fish; John Singleton; Joseph Coffey; Joyce Muench; Judy Albert; Judy Dobbs; Karen Baker; Keith Kolischak; Kevin Richardson; Lynn Hutchens; M. Hurst Marshall; Mary Hampton; Maura Payne; Michael Suggs; Mike Phillips; Murray Jones; Nelson, Byron (WKA); Patricia Lawrence; Patricia Mabe; Peter Schmidt; Phyllis Rumple; R. Keith; Randy Tompson; Richard Williams: Rogene Smith; Roger Mozingo; Seth Moskowitz; Sharon Reid; Sheryl Spainhour; Shirley Miller; Steve Strawsburg; Teresa Wood; Timothy Fields; Timothy Swoope; Tommy Payne; Vickie Parrish; Vicky Pierce; Vivian Tumer; William Cook cc: BCC; Primary Date: 12/3/1999 11:25:31 AM Last Modified Date: 1999-Dec-03 11:25:33 Last Touched Date: Sent Date: 1999-Dec-03 11:25:31 Received Date: 1999-Dec-03 11:25:31 Subject: State Government Relations Weekly Status - 12/02/99 Attachments: SGRw991202.DOC 8 8 & & 2 RJR0000001531090253 ° 70029 3568" ]

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[ "PRINCIPLE INVESTIGATOR: Reuben Eisenstein, M.D. Date of Birth: May 3, 1929 EDUGATION: Tulane University, B.S., 1949, Biology State University, M.D., 1953, Medicine Me, Sinai Hospital, New York, 1954, Intera Presbyterian-St. Luke's Hospital, Chicago, 1957-60, Pathology Resident Professional Experience: Assistant Attending to Attending Pathologist, Presbyterian-St. Hospital, Chicago, IL, 1960-75; Assistant Professor to Professor of Pathology, University of Iilinois Medical School, 1960-69; Professor of Pathology, Rush Medical Colles 1971-73; Dizeczor of Cytopathology, and Surgical Pathology, Presbyterian~St. Luke's Hospita 1965-70; Dizector of Special Pathology, Luke's Hospital, 1970-75; Professe of Pathology, Northwestern. University-Medical School, 1975-80; arcending Pathologist, Menorial Hospital, 1975-80; Director of Chemistry, Immunology, and Serology, Worthvestern Hospital, 1975-76; Director of Leboratories, VA Lakeside Hospizal, 1576-80; Chief, of Pathology and Laboratory Medicine, Mount Sinai Medical Center and Departnent of Pathology, University of 1980-present. Board of Pathology (Anatomic 1959; Clinical 1964). ere.: Menber, B. Stuéy Section, 1967-71; Consul~ fst, Procter and Company, 1973-751 Ad Hoc NELI, 1975, 1979; Medical Advisory Board, Leukenta Foundation, Inc., 1978-present; Editorial Board, Arterdosclerosis, 1980-present; Visiting Professor, several universities, 1965-present. 94 + : B., ayer, Papjiannis, S., Hess, and Ellis, H.: Mineral bindin; by arterial elastic tissue. Lab. Invest., 13:1198, 1964. : 2. E., Eisenstein, R., Sky-Peck, and HéDonald, J.B.: Electron microscopy \" tritiated thymidine in graduation of malignancy of human bladder carcinomas. Te. Am, Assoc. 56:31, 1964, 3. Eisenstein, R., Rosato, J. and Wied, G.: DNA and protein in hypertrophi: human hearts. Proc. Soc. Exp. Biol. Med., 1332176, 1970. 4. Eisenstein, R-, Soble, and Kuettner, K.E.: Lysozyme in epiphyseal cartilage. TI. The effects of on mouse enbryonic cartilage in organ culture. An. J. Path., 60:43, 1970. Eisenstein, R., Arsenis, C. and Kuettner, K.: Electron microscopic studies of carti— Jage matrix using lysozyme as a vital stain. J. Cell Biol.» 46626, 1970. 6. Eisenstein, BR.» Scott, R.A. end Lesak, A.: Altered Lipid binding by mineralized elastin. Arch. Path,, 92:301, 1971. 7. Eisenstein, R., Sorgente, N. and Kuettner, K.E.: Organization of extra-cellular natr of epiphyseal growth plate. Aner. J. Path., 65:515, 1972. 8, Eisenstein, Re, S., Sorgente, N. and Kuettner, K.E.: Collegen-proteoglycan relationships in epiphyseal cartilage. Am. J. 732443, 1973. 3 Eisenstein, R., Sorgente, N., Soble, L., Miller, A, and Kuettner, The resis~ tance of certain tissues to An. J. Path., 73:765, 1973. NO. Sorgence, N., Kuettner, K.E-, Soble, LW. and Eisenstein, The of tain tissues to invasion. Ii. Evidence for extractable factors in cartilage which davasion by vasewlarized nasenchyne. Lab. Invest., 32:217, 1975. 50186844" ]

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[ "LIMITED a OF wer” 27 1970 fir Stouort < a dy Ane 1 House any ter, bene Dye ben 1 longen we fone Hence utd tap Ny bore kit | Tho repuite of the METRE study on the retationenip vetvaen — | and in the united : bo avellable to be used i fn the of | Tho in thu origlnel study covering other i ond bohine the vidi | Gnd of lobe date ney vail prove i toy will to sono extent she for initiating thie study, providing ste cute Se ff end even of the report i fo Intivonce tne end informed epinion hee Seen viviges e oF erguntestione, end in the 1 felt tho right vee for ne, efter vith er Inporiel end taking setount of the vious of tho Tost. Uorking Party, to put proposing a eouree af ection with an vg ef Connitees vith copies te 811 those ved, Provided tho prosossle are 1, ae nenber of the Interin Office, thet the’ progrenne fy proposeie ere based on tho folloving i 1 That uhon the METRA study 48 completed end the report | St uill be of gooe and of interact to export opinion. t 2 Unide At te cloer thet the METRE conclusion thet there Le No in tho Ur | Greenditure ond toral and Failing & tho wsdl Be able fo S| to euch snd to doteties conte" ]

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[ "¥)30 JOHN MURPHY CLOSING REMARKS PHILIP MORRIS'S GROWTH OVER THE PAST SEVERAL YEARS IS WELL KNOWN. WE HAVE NOT GOTTEN WERE WE ARE TODAY BY BEING COMPLACENT, BUT RATHER BY STRIVING TO BE BEST AT WHAT WE KNOW BEST. YOU'VE HEARD QUITE A BIT ABOUT OUR BUSINESSES HERE TODAY. LET ME COMMENT ON SOME OF THE UNDERLYING TRENDS AND SUMMARIZE OUR CURRENT POSITION. FIRST LET'S TAKE A LOOK AT THE U.S. CIGARETTE INDUSTRY. RECENT VOLUME GROWTH HAS BEEN LACKING. WE ARE ALSO CONCERNED WITH THE 6URDEN OF EXCISE TAXES, MARKETING RESTRICTIONS, RESTRICTIONS ON SMOKING, THE SMOKING AND HEALTH CONTROVERSY AND LITIGATION. x 3 x racy + 3" ]

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[ "whk Sorvor 8/26/80 12:86 PAGE Rightrak a. Tobacco Company, Me we age a BRANCH LAW FIRM anc esis ATTORNEYS AND COUNSELORS AT LAW Y a “nee Gok Coit” 2005 Re WW set pe ‘August 25, 1999 . Blizabeth C, David, Esquire ‘Legalgard Information Solutions 617 John F Kennedy Blvd x Suite 700 Philadelphia, PA 19103 Re. Litigation Dear Ma. Davi, nclosed, please find our responses to your letter of August 3, 1999 in connection with the Tobacco Litigation. Although this is not a complete list, I assure you that I am diligently working in order to get you all of the requested. In order for you to complete your audit, I will send the additional information as soon as possible. ‘Thank you for your patience and please feel free to call me if you have additional questions concerning this matter. Sincerely, Kil Parte * “Laurel Keestler Bookkeeper co: Jed Bergman, Eequire cos oe OF = SS z 3" ]

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[ "ol Min", "Jott4", "Au Aam", "Md-Tkn", "Atrhin Hnlur", "Analysis of the Hormone-dependent Regulation of a JunD)-Estrogen Receptor Chimcra (Ccc1ol pl liratiort Kovemlct Trecd orm Februaty 1995/", "Mary Xoy Francisi Honald Fhinncys_ Hnc Kevin Ryden Kotuc Far Ur AeMcnt Ccntct Wilorda Elamo 9] /", "The moduler ligand-hinding donains of steruid reccp elily CUM Jor nnd junl) unden\" 8lmt, Iore ar Ecncratemolein chimerne identical, regulation Cenc-Oa rotcis been widely uAcd trat share high tha ligund dependent for #clivily.In Finilat nilinie dcirc euttuIO acid Rpnuchce ~identity (11. '\"hcy Ara also sitna Uar Lcncrelcc Rcrice conditionally acl Hun) thcir irteraction with c-Fos and Fos-rclated proleins (2). mt Droldins by fusing tficI cnlvoxyl (( (OF)- u ut Jun Cox dimct comnicxcsmd IN at AF'] silcs Jarminn cnGE with (OOA-terminal fragmett Ad rckulia (tc' CutRRi0n LATE4 PnCS . Sirco arid Juan Trogcn rcctmor (EH) thntt conuins Uc ligund. amtily ncmticna rapidly Juduced n TcRuunso extrarciu binding domnin: Junl)EJe (IKII) nud Foir (FKI cki: lar Growth siunls tncy nic cinesuice imnncdiate cark IArX Hiti iulec Lauci zippcr Inic TEun snonE( Ecnt& Kxpression Lnce 0 Eenc Hamilies is exhihit hornon ~onenacn ctivalion aclnttur urO inlcgrul parl of a well-orchcstraled cascadc cvoras leading t0 tcin-]-dirceted trnuecription in transicni exprcSsion MR - ceulat pralilcratior 3nd Tclercnces unortiul Cci GhIc Ont AhteO fusions, IKK , hae no nramTICO pruem HEMIAICLAML Darlicinus the celluler Frowth dctnil decrmninc tucclaniem nction Uacus resunnuro furtoi Eludics analyzing thc direrl checls hese IT olfilittureonilion cxperimcnt: Wte Mrrane mroleing 0I FCIIO crnressiol Truwtn wania dcmonstratc that Ercatly Iromt HEK und Fos iranefccica cclls Cur facilitaled by a wcll characlcrizcd inducible expression syslem. Fos And IKI rendil, arneehntorutinicr omncxtR Onc #pproach for crcating inducible system lucuse : prisingly, the formntion Fos:II heterodimers; plucing te uctivity o protcin under Ihe control ofthc lieatd - #osRInC IFI Fnn] cclimcie troren-inarundcn, uding dumAI sleroid Wanlomo rectuior Ruch Howcvcr, Eel shift ASSAYR clcarly dcmonstrate that I)NA hincing AFI sitcs hy Fos:I)ER hctcrodimcrs IKI Elucocorlicoid receplor (GJ) (hc CstIOgch rereptor (KKA St - homodimcra cAtrogon-dopondena.Mor Ovcr, Ihcal- FCI hsimi urolems HaVC [icl crealed wilh proteins GcnCO cetroecn Inc nhi wrotcin un cflectivc inhil Such os FIA (4), c-Myc (54 the CCAATenhancer-binding \"f Fosaliuded transuclivudict, this fIfect i6 (61, Myol) (7), 053 (8L, and c-Fos (9, J0la cach LHced roicreco thc #rcscnce ul ceirolem Qur Teauils Iudi - Cheds the fusiou pratein HACiunto be' devoid biological M thc IEI pratein dircct, ormono-rovcre- pcliv Mncia eXpr\"ssed in cellz in thc ahscnco Hgrmnan ible inhibitor of Fos and that estrogen etrols tne con- Akcrae iu appropriate wild Vyn (W\") functioni was reclored ditione uneilirc 0 dounAn ncgativc nctivitice UEI in thc prctcncc harugn thc level INA binding Fi ? Accordinely Wc explored thc possibilit; thc aclivitins WT' end conely dcrivcrGbrnhlasi ccll lincs (hat stably cxptoss mamlAtod ruemin could I reculaled Ws tranelationally thc IFI prulcin exhibit reduced fnlri Iuto tnc Mfuni (' by fusion with tho FK Uun) chinioric nioloculo R croated of thc cell crclc Han quiosccnt 0s ni ' Ecruni ema apncndinp' trunculed WAA KK sucuLCO' ntad in the Alnent raruren Thic conire rerulting thc Jun)-EK (IEI) fusion. Analy-is IEK estrogcn-trcated controls_ ncso rcsuil suppOrt tha Jueinn nrolcn #hout that estrocet doncnacni for thc hypathesis thnt Al\" Bn is imporlant cll crclc uroeros- MchAe tranacription from AF] rcporlcr Constrct Rion Atid Drovido uniduc AnnTOAOn examining thc addilioml; detailcd analysis of the nicchanism by which esto- role of AF'] in thif proccss, nculale? IC Vtolci pcrlorjucd Thc chimera fortur het erodizuet? wilh WT\" Fos proteins but docs Jot readily hecruditcrs with WY Jun proicins. Hawevcr, ncither the Melien LMc' Jun and For familics of on oproleins Are tho Cna Tulerachons ncucmi IEK and W' Jun nor Elrone CLCCWE COI[OLCIIL ~ of the dimeric U ausc!iplion Inctor \"cti- interactions hctwccn IER and Fos are rCgulaled Vv (stroccn; F prateit- (AF'T)\" Thc thrcc mucnut no Fut Fetc corLTasL, IINA binding by HER homodimcrs FERFos elcrodincn- complctcly stropen-dependent_ ccauc thi& novel micchanisu \"clion; thc IFR fusion prolein bupnorlt& Fwllic Ilcaltl Scrvice Girnml; UaKalatal lunitle Cirmn cilectvc DuIMMML JcGative protein that complexcs with Fos 32in (e-ng 4HU:' 408u' UaC Eaniceanaran_Amn Cant Moll FSn Glo- #IIc] reversiblt imniituts IS IONA binding: #clivity- Ju addition, Myela (Juicolors neinecd Goela puwicalion cell clones that slably express the IFF prolelo exhibit ailiclt #ert ucitalco want by thc payiuchl cliaigs uuced CamaCIL Gucr phasc from Froxth ATrestcd &lulc arlicle tusl tnciclone hcrony nuirkoFaducelist !ch ( Aaceuroamge in thc uuscnCC ealracen rosult thal consislent witn Ceclion ]734 &lchy Indicntt METHII the hypothesis that AF] IIIIiciriatL Joranal ccll cyclc Felltw Itt Nalional Iuclitulcf Hcalih and nripicng 74-V219 pruprt#SIuI Fcllow _ thc Ancricnn Cancer Socicly: Whilc Mmtecr ticonne chimeras bclwccn steroid T tom cotcemandcnccehould WldtetRL 215-726-2889. 415724.36 TAHedar Mnacd AroA\" Actmnr #retm C;l, clurocor- Wiculdrceuigr KK Ualncenecelant #TI ; wild ty \"c; rCipalyuctasc becco'& modilied Kaglcie wc-dium; FHS, Icta Fovine #crun; ]*, thyroid dreaciol CATchlorennuhonicnl Acoretrenalcrasn HIMKM, Iuk: horJlOIIC Tccenior_KAK rolit oic ecid receptor,", "11502", "PUBLICATIONS", "0050408" ]

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[ "Dini lined of Oi: UL (LO Cotta UM oh Vee ef need Bove of AO pal ORE Hate seh bard ke ne nt he pi Ong omit ony ofp Hol Mend aad) Pine we Aan Lind fee aol Lani . | yey MR | | |" ]

[ [ 0, 113, 689, 655 ] ]

3

1,000

777

presentation

[ "American Medical Association", "Physicians dedicated t0 Lhe heallh of Americz", "News Release", "FOR", "IMHEDIATE RELEASE", "For", "further", "inforoat ion ,", "Linda", "Cotsen,", "contacta", "312/464-4443", "Fingland", "202/245-7163", "HITHDRAHAL", "\"OLD JOE", "CAMEL", "ADS", "URGED", "AMA _", "0.$", "SURGEON", "GENERAL", "MASBINGTON,", "March", "ican", "Medical", "The", "Amer", "Asgociation", "and", "United", "States", "Surgeon", "General", "Novello,", "MPE , today", "Antonia", "called", "for", "the", "voluntary", "R.J_", "Reynolds", "advertising", "remoua", "Tobacco Company of", "al1", "using", "che", "Old", "Joe", "Cane [", "cigarettes", "character", "to pronote", "Novello urged all", "The", "AMA", "retail", "cigarette", "outlets", "cemove", "promot", "onal", "materials", "ing", "the ca", "fcom stores", "toon", "also", "charactor", "They", "asked", "Dagazines", "and", "neuspapers", "billboard compan", "Camel", "ads with", "refuse", "the", "O1d", "format", "Camel", "Joe", "Studies", "ished", "the Joucnal", "publ", "the", "Medical", "American", "4350c44t40n", "(JAHA)", "last", "December", "Old", "reported", "that", "Joe", "recogni", "ion", "factor", "among", "six-year-olds", "of the Disney", "equal", "their", "Identification", "4ag", "Hickey", "1o90", "Channel", "House", "related", "tudy shoved", "that", "advertiging", "Lobaccc", "ins", "promores", "anc", "Maint ?", "nicot ine", "addiction", "children", "amono", "1dolescents", "\"R.J. Reynolds", "4ing", "aoverta", "and", "Cancl cigarettes", "prOmot ion of", "has", "been", "targeting chfldren.", "James", "must", "sEoP ,", "Todd", "vicc", "R2ad", "exccutive", "ident", "the", "Reynolds", "tempt", "icism", "Prer", "ArA -", "R.J", "halt", "releasIng", "series of", "ads", "egedly", "designed", "ney", "dissuade", "chfldhood", "disingenuous", "and", "snokers", "smoke", "gcreen", "1", "mores", "615 North Stalc Surert", "Chiato,", "Ilnois 64510", "312464440" ]

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[ "American Medical Association Physicians dedicated t0 Lhe heallh of Americz", "News Release", "FOR IMHEDIATE RELEASE", "For further inforoat ion , contacta", "Linda Cotsen, 312/464-4443 Fingland 202/245-7163", "HITHDRAHAL \"OLD JOE CAMEL ADS URGED AMA _ 0.$ SURGEON GENERAL", "MASBINGTON, March The Amer ican Medical Asgociation and United States Surgeon General Antonia Novello, MPE , today called for the voluntary remoua R.J_ Reynolds Tobacco Company of al1 advertising using che Old Joe Cane [ character to pronote cigarettes", "The AMA Novello urged all retail cigarette outlets cemove promot onal materials ing the ca toon charactor fcom stores They also asked Dagazines neuspapers and billboard compan refuse Camel ads with the O1d Joe Camel format", "Studies publ ished the Joucnal the American Medical 4350c44t40n (JAHA) last December reported that Old Joe recogni ion factor among six-year-olds 4ag equal their Identification of the Disney Channel Hickey House 1o90 related tudy shoved that Lobaccc advertiging promores anc Maint ? ins nicot ine addiction amono children 1dolescents", "\"R.J. Reynolds aoverta 4ing and prOmot ion of Cancl cigarettes has been targeting chfldren. must sEoP , R2ad James Todd exccutive vicc Prer ident the ArA - R.J Reynolds tempt halt icism releasIng ney series of ads egedly designed dissuade chfldhood snokers disingenuous and smoke gcreen", "1 Chiato, 615 North Stalc Surert 312464440 Ilnois 64510", "mores" ]

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12

754

1,000

budget

[ "New", "Tobacco", "Association", "1999", "Budget", "State", "Activities", "Division", "($000)", "Cost", "Center", "1400", "Account", "4300", "Rent", "-", "Office", "Space", "1999", "portion", "of", "lease", "obligations", "for", "six", "Tobacco", "Institute", "$37", "field", "offices.", "Office", "leases", "for", "three", "New", "Tobacco", "Association", "field", "90", "offices.", "(1,500", "s/f", "@", "$20", "x", "3)", "3127" ]

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[ "New Tobacco Association 1999 Budget State Activities Division ($000) Cost Center 1400 Account 4300 Rent - Office Space 1999 portion of lease obligations for six Tobacco Institute $37 field offices. Office leases for three New Tobacco Association field 90 offices. (1,500 s/f @ $20 x 3) 3127" ]

[ [ 71, 153, 595, 470 ] ]

10

754

1,000

specification

[ "LUXURY", "CR", "LTS)", "REGULAR", "Beans", "cone", "cucanerte", "woe", "ere", "15.6", "kop", "|", "\"25.00", "Tonacco", "nop", "ve", "ve", "Tb.", "we", "20", "racer", "“Boe", "PAPER", "UPs", "MIITE", "TOL", "CER)", "XE", "256K2", "LASER", "PERF.", "REPLACE", "MITH", "TEAM", "X", "MITE", "TOL", "CCR)", "LASER", "PERT.", "uur", "+", "REFER", "TO", "ENGINEERINGS", "GLUE", "ROLLER", "VARIABLE", "PARTS", "CATALOG", "|", "SY", "AND", "CIGARETTE.", "TYRE", "TPR.", "CUT", "Size", "TIPPING", "TIPPING", "ADHESIVE", "+", "NATIONAL", "32-2087", "ev", "sean", "+", "NATIONAL", "52-2100", "CPROTOS", "100/HK", "10)", "EVA.", "61-490-", "570.", "FILLER", "©", "PADK", "=", "18.60%", "VIRGINIA", "SLIME", "LIGHTS", "REGULAR", "Fr", "CHOAREYTE", "FLAX", "+", "sac", "FoR", "PRINT", "OTE", "AND", "EXPORT", "cute", "CRE", "DHE", "REF", "SAP", "CROSS" ]

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[ "LUXURY CR LTS) REGULAR Beans cone cucanerte woe ere 15.6 kop | \"25.00 Tonacco nop ve ve Tb. we 20 racer “Boe PAPER UPs MIITE TOL CER) XE 256K2 LASER PERF. REPLACE MITH TEAM X MITE TOL CCR) LASER PERT. uur + REFER TO ENGINEERINGS GLUE ROLLER VARIABLE PARTS CATALOG | SY AND CIGARETTE. TYRE TPR. CUT Size TIPPING TIPPING ADHESIVE + NATIONAL 32-2087 ev sean + NATIONAL 52-2100 CPROTOS 100/HK 10) EVA. 61-490- 570. FILLER © PADK = 18.60% VIRGINIA SLIME LIGHTS REGULAR Fr CHOAREYTE FLAX + sac FoR PRINT OTE AND EXPORT cute CRE DHE REF SAP CROSS REFERENCE 9: FILTER: 070198 contenrs PAPER REFLECTS CORE REDUCTION Wo PERF TAGS. EASON FOR «TRG PAPER UPDATED TO A PRESSURE DROP ci, a FS U/ 3 1 To REDUOE DILY AVG TO Ter. RENOVED, DEPLETED. MO TO DC CIGTS. = peanrane Date PREPARATION DATE SUPERCEDES SPECIFICATION 4/01/97" ]

[ [ 79, 140, 701, 954 ] ]

7

762

1,000

memo

[ "a>", "Qos", "(2)", "J.W,", "Dorygard", "i", "xt.", "pues", "peo", "Sty", "2050", "=", "sates", "voluce", "of", "6,751", "xeprosents", "on", "average", "204.4", "million", "per", "gay", "ao", "1867,", "or", "an", "|", "Gherenve", "of", "202%", "i", "average", "and", "the", "parcent", "change", "MUSIC", "hae", "nonin", "of", "Lau", "cmtained", "28", "Sige", "wich", "the", "caye", "over", "29", "bolas", "a", "and", "32", "Gaye", "sith", "the", "ays", "20", "being", "=", "october", "1909", "1068", "GT", "Bayo)", "i", "aug", "Dolly", "to", "Brand", "Ya.", "1907", "i", "as", "se", "ee.", "wa", "ke", "re", "aD", "as", "=", "3", "ae", "as", "re", "you", "xo", "Fitter", "wee", "+", "2", "Boon", "ay.", "2", "o>", "st", "so", "0?" ]

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[ "a> Qos (2) J.W, Dorygard i xt. pues peo Sty 2050 = sates voluce of 6,751 xeprosents on average 204.4 million per gay ao 1867, or an | Gherenve of 202% i average and the parcent change MUSIC hae nonin of Lau cmtained 28 Sige wich the caye over 29 bolas a and 32 Gaye sith the ays 20 being = october 1909 1068 GT Bayo) i aug Dolly to Brand Ya. 1907 i as se ee. wa ke re aD as = 3 ae as re you xo Fitter wee + 2 Boon ay. 2 o> st so 0? he uns Vasa . 28.0 + 3.0 i sane wa toed ene ro Fitter 327 ao Su 3 aS Se 2 TT ale “ALL 28 ~ 2 252.5 soe + 58 17 mae run nice uss Tatas oe eine (QUALITY OF THE FILMED. 3 10" ]

[ [ 28, 185, 681, 909 ] ]

15

778

1,000

questionnaire

[ "RESULTS", "|", ".", "|", "|", "t", "|", "a", "g", "|", "5", "3", "|", ".", "8", "|", "3", "|", "Be" ]

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[ "RESULTS | . | | t | a g | 5 3 | . 8 | 3 | Be" ]

[ [ 0, 454, 750, 1000 ] ]

13

762

1,000

memo

[ "BROWN", "f&", "WILLIAMSON", "TOBACCO", "CORPORATION", "RESEARCH", "&", "DEVELOPMENT", "THTERNAL", "Tor.", "B.", "A.", "Reasor", "ce:", "A.", "H.", "L.", "Reynolds", "B.", "A.", "Kerr", "AL", "3.", "Golub", "H.C.", "Woerte", "A.", "P.", "L.", "Chen.", "A.", "Goodman", "DATE:", "November", "2,", "1990", "SUBJECT:", "DUPONE", "RESULTS", "FOR", "MENTHOL", "PERCEPTION", "BELATR", "LTS", "-", "RIGH/313", "DETAILS", "Attached", "are", "Monadic", "Attribute", "and", "analytical", "results,", "The", "following", "products", "were", "evaluated:", "313080", "~", "0.65%", "MENTHOL/CONTROL.", "313081", "—", "0.75%", "MENTHOL", "313082", "~", "0.82%", "MENTHOL", "313083", "-", "0.91%", "MENTEOL", "313084", "~", "1.00%", "MENTHOL", "Monadic", "Attribute", "ratings", "were", "made", "by", "54", "LD-M", "KS", "smokers", "and", "9", "PRISM", "paneliste.", "‘The", "Dupont", "study", "I.D.s", "were", "900253", "and" ]

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[ "BROWN f& WILLIAMSON TOBACCO CORPORATION RESEARCH & DEVELOPMENT THTERNAL Tor. B. A. Reasor ce: A. H. L. Reynolds B. A. Kerr AL 3. Golub H.C. Woerte A. P. L. Chen. A. Goodman DATE: November 2, 1990 SUBJECT: DUPONE RESULTS FOR MENTHOL PERCEPTION BELATR LTS - RIGH/313 DETAILS Attached are Monadic Attribute and analytical results, The following products were evaluated: 313080 ~ 0.65% MENTHOL/CONTROL. 313081 — 0.75% MENTHOL 313082 ~ 0.82% MENTHOL 313083 - 0.91% MENTEOL 313084 ~ 1.00% MENTHOL Monadic Attribute ratings were made by 54 LD-M KS smokers and 9 PRISM paneliste. ‘The Dupont study I.D.s were 900253 and 900254, COMMENTS None. } P. A. Goodman 26171 505501605" ]

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[ ". : 4 . it 42nd tew York, New Yo 3 New 30007 SS fate : Circular No. 2486 May 5, 1971 3 ade : ANNOUNCING KENT MENTHOL KING SIZE CIGARETTES 0 OUR CUSTOMERS IN THE STATES OF: ‘ALABAMA ARKANSAS NORTH DAKOTA KANSAS. OKLAHOMA th MISSISSIPPI MINNESOTA NEBRASKA COLORADO TEXAS LOUISIANA SOUTH DAKOTA WYOMING NEW MEXICO” § FLORIDA: The following Counties: 3 Holmes Washington Bay Santa Rosa Watton Jackson cult ILLINOIS: The following Counties: Madison Moncoe : Except Scott County * WISCONSIN: Douglas County only, KENT got it all together again . . . NOW THERE'S KENT MENTHOL KING SIZE TOO! with the exclusive Micronite Filter .. . and the good rich taste of KENT. We've taken all the good things of KENT MENTHOL ig 1100's, and got them together for sniokers who prefer KING-SIZE. LIST PRICE: $10.25 per M. TERMS: ‘We will allow special discount terms as follows: THE TOTAL 3% DISCOUNT WILL BE AVAILABLE ON 4NVOICES FOR KENT MENTHOL KING SIZE DATED. THROUGH MAY 26, 1971. 1F PAYMENT IS RECEIVED AT OUR REMITTANCE ADDRESS NO LATER THAN THE 30TH DAY AFTER INVOICE DATE. ‘THESE SPECIAL TERIAS WILL APPLY ONLY TO KENT MENTHOL KING SIZE LS TO PURCHASES UP 10 THE AMOUNT OF YOUR ALLOCATION. PACKING: KING SIZE Cup (soft) packages of 20's, cartons of 200, shipping containers SHIPMENTS: First deliveries of KENT MENTHOL KING SIZE Cigarettes will be made May td 13, 1971 to Lorillard customers in the areas outlined above. ALLOWANCE: — An Introductory allowance of per M ($6.00 per case of 12M) will be | BW given on KENT MENTHOL KING SIZE Cigarettes beginning May 13, 1971 oe through May 28, 1971, This allowance will be deducted ftom the face of invoices and applies to purchases of KET MENTHOL KING SIZE only. i Pa gfe - . 7 ve" ]

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[ "RJRI INI , INC,", "aJ: Reynolds Tobacco Interational Inc Feb TI Rc 1902 Jjrt Form 0d0] RUr CHANGT/2-82 AUTHORIZATION FoR Den fion Date January 21 , 1982 Operating Area /Unit Area III Brazi] AC No_ BR 002-82 Subject /Location New_Brand Introduction (Test Market) Came] Filters Unit Ref. MAP-9-1982", "Approvab Requested This request Rpreve\" for the introduction of Came Filters into the Curitiba Test Market on Apri 1982 the introduction of Came Filters the brand group wants to tes exploiting marke Camepportunity that has recently been dentified, Specifically the brand group proposes to test Filters an alternative to Ho]lywood taking eydvanesgeb9ishc of Ho] Iywood product Tife maturity Moreover Came Filters has unique opoo portunity itself ma le cigarette without the usua Iy negative perceptions of and too downscale Currently there no cigarette in the market with such unique 9659893 oning If after twenty our weeks Came] Filters achieves its 0 SOM objective and has shown ievel, tnat can sustain this share the brand wil) be ro] led-out nationa ly on October 25, 1982", "L-J+I", "(Attach Summar Discussion ol Roporal)", "Type of Change Selling Price Change Expense Chenge Raw Materials Salary. Wage Scales Fringe Benefits Headcount Change Other Policy Change LX New Product Introduction", "Contractua Commitment (Specify Type) Working Capital Change Inventories Receivables Other Amount of Change: Change from Budget /Plan: Other ,_", "0 {", "BEST COPY ,", "Is this lated previous proposal? Will subsequent commitments required?", "Yes Yes", "Yes, describe attached Iummtn diccussion", "Initia Post Evaluation Date Sept_22 982 VHENY AHNU 19 86 3,416 1,845 3,416", "19_82 637 884 322", "19 85 2,643 1.427 2,643", "Eximuted Profit/Loss lmpuct: Earnings From Operations Earnings From Operations(Aftax) Budoet /Plan EFO Change", "738) (399) (738)", "430", "232 430", "APPROVALS OPERATING UniT AREA H.a: Signature Date Signature Date Signature Brand Mgnt. Jo_LL Ji2sL Pig:Pla ' Yi44 Pir.Lega] RI eez] EE82 xhbx Oper_ Iixa Zneb Lsla Fin Liky", "RJrTi", "Date", "Mktg.", "Rres idew" ]

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1

1,000

754

presentation

[ "12/s(14", "(BAPensATin", "KozolouJJk ;", "DveArEads", "Compensation", "Compensation and Low", "Yield Cigarettes", "Lynn \"", "Kodowekl PhD:", "Does", "brand-swilching", "Prolateot4nd Hled", "smoker", "oversmoke", "Progrm", "Blobahavoral Haaltn", "lower nicotina cigaretto?", "Colleot-", "Haalth end Human Davelopmani", "Th Pennaylvnui sub Unlvrlty", "Answor: Yes:", "Unlverelly Perk PA 16402", "Ground Rules", "\"Hydraulics\"", "Per clgarotto adjustments only", "The FTC Iost @ 4 por-clgaratto tost", "approximate what would happen If", "should be judgad", "Ruch", "number ot cigarettes were fixed_", "Forty low calorle candy ban May", "~2 mg X 20 cigs", "mglday", "togolhar be hlgh calorle and atIII", "~4mg X 10 cigs", "mglday", "Indlvidually bt low calorlo.", "~0.8 mg X 5 cigs", "mgday", "Importance of brand-", "Compensatory % Chango in", "Cigarettes per Day", "switching research_", "Repeated-measures deelgns", "Mean", "+15%", "control Ior individual dlilerences:", "(95% Cl=t6)", "~dnug Motabollem", "brnd golaetlon", "blaser", "(#ussortatlve mating )", "[No decreased intake]", "Page", "89241644" ]

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[ "(BAPensATin 12/s(14", "KozolouJJk ; DveArEads", "Compensation", "Compensation and Low Yield Cigarettes", "Lynn \" Kodowekl PhD: Prolateot4nd Hled Progrm Blobahavoral Haaltn Colleot- Haalth end Human Davelopmani Th Pennaylvnui sub Unlvrlty Unlverelly Perk PA 16402", "Does brand-swilching smoker oversmoke lower nicotina cigaretto?", "Answor: Yes:", "Ground Rules", "\"Hydraulics\" Per clgarotto adjustments only approximate what would happen If number ot cigarettes were fixed_ ~2 mg X 20 cigs mglday ~4mg X 10 cigs mglday ~0.8 mg X 5 cigs mgday", "The FTC Iost @ 4 por-clgaratto tost should be judgad Ruch", "Forty low calorle candy ban May togolhar be hlgh calorle and atIII Indlvidually bt low calorlo.", "Importance of brand- switching research_ Repeated-measures deelgns control Ior individual dlilerences: ~dnug Motabollem", "Compensatory % Chango in Cigarettes per Day", "Mean +15% (95% Cl=t6)", "blaser brnd golaetlon (#ussortatlve mating )", "[No decreased intake]", "Page", "89241644" ]

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12

718

1,000

scientific publication

[ "Jounal", "of", "$13", "(1993)", "95103", "Evie", "BV,", "Amsterdam", "chromato,", "High-performance", "liquid", "chromatographic", "determination", "of", "nicotine", "and", "its", "urinary", "metabolites", "via", "their", "1,3-", "diethyl-2-thiobarbituric", "acid", "derivatives", "Klaus", "Rustemeier*,", "Demetrios", "Demetriou,", "Georg", "Schepers", "and", "Peter", "Voncken", "fr", "2,", "W-S000", "Kan", "90", "(Fi", "ane", "288,", "1992;", "November", "TR,", "1992)", "ABSTRACT", "‘The", "|", "igh", "fr", "rictne", "ha", "been", "hat", "ican", "be", "wed", "determine", "the", "concentration", "of", "nine", "nd", "upto", "1", "bole", "ine", "urn", "of", "humane", "ne", "Wbortoy", "ail,", "plate", "tebe", "“Th", "produts", "of", "lavage", "found", "in", "ite", "vere", "nil", "ene", "cosine.", "aa", "sal", "mount", "Felloving", "anaes", "showed", "the", "ofthe", "rietne", "DETEA", "dernatne", "1", "te" ]

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[ "Jounal of $13 (1993) 95103 Evie BV, Amsterdam chromato, High-performance liquid chromatographic determination of nicotine and its urinary metabolites via their 1,3- diethyl-2-thiobarbituric acid derivatives Klaus Rustemeier*, Demetrios Demetriou, Georg Schepers and Peter Voncken fr 2, W-S000 Kan 90 (Fi ane 288, 1992; November TR, 1992) ABSTRACT ‘The | igh fr rictne ha been hat ican be wed determine the concentration of nine nd upto 1 bole ine urn of humane ne Wbortoy ail, plate tebe “Th produts of lavage found in ite vere nil ene cosine. aa sal mount Felloving anaes showed the ofthe rietne DETEA dernatne 1 te ie ef DESTA an the wk of nicotine INTRODUCTION low [6] reported that, by using an extraction pro- cedure, the sensitivity of the assay was enhanced, In recent years the metabolism of nicotine has et af, [7], in addition to determining been found to be very complex, Moré than 20 nicotine and cotinine, were able 10 determine urinary nicotine metabolites have been described three identified metabolites vsing modified chro- (1). For their determination in the urine of hu- matographie conditions. Barlow er al. {5} and mans and laboratory animals, an appropriate O'Doherty eral (7] proposed that the mechanism analytical method is required, However, only a of the derivatization reaction is based, analogous few methods that can quantify more than two to the reaction (8), ona sing-opening reac- metabolites simultaneously have been reported, _ tion of the pyridine substructure, starting with an and these generally require the use of electrophilic attack on the pyridine nitrogen, If ly labeled nicotine Barlow er af. de- this is true, only those metabolites that scribed a pre-column derivatization method an intact pyridine ring and bear no substituent at yielding acid (DET- the nitrogen atom can undergo this reaction. This BA) derivatives, which can be separated by high- is the case for the majority of the known nicotine performance liquid chromatography (HPLC), metabolites with few exception, eg. cotinine-N- ‘They were able to determine nicotine and coti- oxide and the previously reported Neglucuro- nine. In addition, they observed five metabolites _nides (9). that they could not identify, Parviainen and Bar- This paper describes the extension of the HPLC assay to detect and quamtty all those me- tabolites in the urine of humans and laboratory g * Corresponding author. animals that form DETBA derivatives, As the 3 g $06.00 ©1993 Elsevier Science Publishers All ighiseeseried 3" ]

[ [ 56, 82, 657, 887 ] ]

6

754

1,000

questionnaire

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[ "ra ‘T-127 032387/1 cigarettes Hello, I'm of . We are conducting a brief survey on cigarettes and would like to include your opinions. 1. First, is there anyone Living in your household who is enployed in the sale, manufacture or distribution of tobacco products, or in market research, or advertising? Yes (TERMINATE) No 2. Is there a person living in your home between the ages of 21 and 59 who snokes at least 10 cigarettes per day? ves No. (TERMINATE) 3. May T speak to that person? (IP NOT AVAILABLE, MAKE APPOINTMENT 70 CALL LATER. SAVE SCREENER. GET NAME AND TELEPHONE NUMBER.) 4. Is your regular brand of cigarettes a filter or non-filter 8 cigarette? Filter g Non-filter & 8 5. Is your regular brand of cigarettes menthol or non-menthol? Non-menthol" ]

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[ "2077981575 yp Page 1 as 4 : Note for Mahon, Jean yp ie 4 A From Mulderig, John ye w Date: Fri, Jan 3, 1997 6:43 AM \\ iP Subject: RE: Records os Se J To: Mahon, Jean; Purcell, Clare ti \\A aw! a ce: King, Valerie ak ¥ Based on your brief description, I end to doubt that any of the materials have any value to in the role she now plays and do not see much purpose in moving the records to Jean, You and Clare can discuss and determine if they have vaiue to Jean's position in its present form. If the records do not have any present use, they should be evaluated for disposal suspension and if on disposal suspension, permanently retained as part of Clare's inactive files. Bill Lynch can assist in the evaluation, Tf not on disposal suspension, the records should be managed pursuant to applicable records retention schedules and procedures for records not on disposal suspension, John" ]

[ [ 20, 115, 682, 442 ] ]

2

1,000

754

handwritten

[ "AuLLEL", "Zau", "Z", "Z1z L", "Zeez", "Lzz", "[L1", "LL4 Z", "Ezz", "Zz", "El", "2LLill z", "Zcusss", "ZiLLe'", "7a2", "1iLea&", "Zz", "7Z2", "ZUA", "Zis -DIEeE", "7udus", "4ze23", ":", "$51", "272 =", "82", "1" ]

[ [ 439, 600, 566, 637 ], [ 119, 603, 177, 639 ], [ 208, 604, 284, 634 ], [ 472, 628, 564, 658 ], [ 354, 636, 464, 688 ], [ 136, 638, 204, 662 ], [ 307, 641, 361, 661 ], [ 218, 642, 299, 662 ], [ 133, 659, 255, 721 ], [ 216, 660, 290, 690 ], [ 532, 662, 572, 686 ], [ 577, 695, 661, 711 ], [ 606, 712, 684, 738 ], [ 244, 716, 336, 742 ], [ 486, 716, 598, 744 ], [ 125, 720, 234, 749 ], [ 132, 744, 192, 770 ], [ 201, 749, 257, 769 ], [ 374, 761, 481, 797 ], [ 359, 789, 597, 832 ], [ 366, 814, 466, 858 ], [ 581, 818, 668, 848 ], [ 685, 819, 699, 857 ], [ 566, 846, 624, 872 ], [ 354, 848, 438, 876 ], [ 452, 848, 494, 874 ], [ 685, 863, 699, 901 ] ]

[ "Zau Z AuLLEL Lzz LL4 Z [L1 Z1z L Zeez Zz El Ezz 2LLill z 1iLea& ZiLLe' 7a2 Zcusss Zz 7Z2 ZUA Zis -DIEeE 7udus 4ze23 : 272 = 82 $51 1" ]

[ [ 119, 600, 699, 901 ] ]

3

Split	Échantillons	Pourcentage
Train	9,511	69.9%
Validation	2,033	15.0%
Test	2,056	15.1%
Total	13,600	100%

Label	Catégorie	Description	Échantillons
0	letter	Lettres et correspondance	822
1	form	Formulaires	828
2	email	Emails imprimés	868
3	handwritten	Documents manuscrits	861
4	advertisement	Publicités	866
5	scientific report	Rapports scientifiques	842
6	scientific publication	Publications scientifiques	866
7	specification	Spécifications techniques	845
8	file folder	Dossiers de fichiers	857
9	news article	Articles de presse	845
10	budget	Documents budgétaires	867
11	invoice	Factures	841
12	presentation	Présentations	845
13	questionnaire	Questionnaires	859
14	resume	CV et résumés	834
15	memo	Mémos	854

Métrique	RVL-CDIP Original	Notre Dataset	Amélioration
Échantillons	4,000	13,600	+240% 🚀
OCR Coverage	Partiel	100%	Complet ✨
Mots/Document	~45	~79	+76% 📈
Features	6 basiques	9 complètes	+50% 🎯
Équilibrage	±15%	±3.4%	4x mieux ⚖️

Datasets:

HAMMALE
/

rvl_cdip_OCR

📊 RVL-CDIP OCR Enhanced Dataset

🎯 Description

🚀 Caractéristiques Principales

📈 Volume et Qualité

🔍 Features OCR Avancées

📊 Statistiques du Dataset

💻 Usage

🔥 Chargement Rapide

🎯 Features Disponibles

🏷️ Classes de Documents (16 catégories)

🤖 Modèles Compatibles

✅ Support Natif

🚀 Performance Attendue

📊 Comparaison vs Datasets Standards

🛠️ Applications

🎯 Cas d'Usage

🔬 Recherche

📚 Citation

🤝 Contribution et Support

📄 License