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NCT02266745 | 44:56:cancer | imaging by Response Evaluation Criteria in Solid Tumors (RECIST v1.1, Appendix 2) | 1 | [
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NCT02037048 | 37:53:chronic_disease | Patients with a clinically apparent active infection will not be eligible (please note, an isolated elevation in the white blood cell count, by itself, does not constitute evidence of an infection) | 1 | [
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NCT02311621 | ,16:37:treatment,42:73:treatment,86:104:treatment | ≥ 6 weeks from myeloablative therapy and autologous stem cell transplant (timed from stem cell infusion) | 1 | [
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NCT03005418 | 1:22:treatment,157:184:chronic_disease,232:249:treatment | Autologous vein graft is either not feasible in the judgment of the treating surgeon (e.g. because of lack of availability of suitable conduit, presence of severe venous insufficiency) or is not desirable because of the urgency of revascularization | 1 | [
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NCT02271711 | 135:151:treatment | Extensive disease, disease location, and/or co-morbid condition that the PI or designee considers unsafe for surgical intervention of NK cell infusion | 1 | [
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NCT02707692 | 12:34:chronic_disease | History of Gullian Barre syndrome | 1 | [
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NCT02454517 | 13:35:chronic_disease,,103:124:chronic_disease,128:134:chronic_disease,136:151:chronic_disease,153:164:chronic_disease,166:178:chronic_disease,180:195:chronic_disease,262:274:chronic_disease,,,,,365:375:chronic_disease,377:390:chronic_disease | Significant cardiovascular disease precluding an exercise program, including recent (within 6 months) myocardial infarction or stroke, pulmonary edema, myocarditis, pericarditis, unstable angina, pulmonary embolism/deep venous thrombosis (PE/DVT), uncontrolled hypertension (systolic blood pressure [SBP] > 200; diastolic blood pressure [DBP] > 110), uncontrolled arrhythmia, heart failure | 1 | [
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NCT02401347 | 1:49:cancer | Brain or central nervous system (CNS) metastases | 1 | [
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NCT01898793 | 46:58:allergy_name | Known hypersensitivity to one or more of the study agents | 1 | [
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NCT02031250 | 43:55:treatment | Patients must be able to receive protocol chemotherapy in the judgment of the treating Medical Oncologist | 1 | [
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NCT02496663 | 38:46:treatment,48:59:treatment,61:93:treatment,111:137:treatment | be treatment naive to 3rd generation EGFR-TKI (rociletinib, EGFR inhibitor HM61713 [HM61713] and AZD9291) and EGFR monoclonal antibodies | 1 | [
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NCT02567422 | 22:34:treatment | Patient who requires live vaccine administration | 1 | [
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NCT01976585 | 13:35:chronic_disease,,55:79:chronic_disease,81:102:chronic_disease,,127:142:chronic_disease,144:164:treatment,189:208:chronic_disease,212:243:chronic_disease | Significant cardiovascular disease (i.e. NYHA class 3 congestive heart failure; myocardial infarction with the past 6 months; unstable angina; coronary angioplasty with the past 6 months; uncontrolled atrial or ventricular cardiac arrhythmias) | 1 | [
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NCT02323880 | 51:61:cancer | patients must have had histologic verification of malignancy at original diagnosis or relapse | 1 | [
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NCT02557321 | 1:71:cancer | Stage IV or Stage III (unresectable, in-transit or satellite) melanoma | 1 | [
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NCT02495545 | 18:40:treatment, | Participation in another clinical trial within the past 30 days | 1 | [
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NCT02572791 | ,59:75:chronic_disease,100:127:treatment,140:148:treatment,168:191:treatment | Patients with traditional risk factors for HA-MRSA (e.g., immunodeficiency, indwelling catheter or percutaneous medical device, undergoing dialysis, presenting with a surgical site infection, or residing in a long-term care facility within the past year) | 1 | [
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NCT02146924 | 30:43:treatment | he/she must have appropriate venous access | 1 | [
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NCT00711373 | 1:10:chronic_disease | Blindness: blind amputees may be poor candidates because sensory return in the hand may not provide sufficient protective sensation | 1 | [
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NCT02111850 | 1:36:treatment | Concurrent systemic steroid therapy | 1 | [
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NCT01829958 | 38:47:treatment | Must meet criteria for initiation of treatment | 1 | [
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NCT02004275 | ,,228:240:treatment | Must either commit to complete abstinence from heterosexual contact or begin TWO acceptable methods of birth control, one highly effective method and one additional effective (barrier) method, AT THE SAME TIME, before starting pomalidomide | 1 | [
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NCT02582827 | 1:18:treatment,74:96:chronic_disease,101:125:chronic_disease | Electrocardiogram findings suggestive of significant current or previous ischemic heart disease, or left bundle branch block | 1 | [
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NCT01754298 | 1:13:treatment | chemotherapy treatment | 1 | [
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NCT02633111 | 32:59:cancer | Histology-confirmed aggressive B-cell Non-Hodgkin lymphoma | 1 | [
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NCT01989546 | 77:93:chronic_disease,95:131:chronic_disease,133:157:chronic_disease,159:177:chronic_disease,182:201:chronic_disease | Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements | 1 | [
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NCT02920710 | 12:22:cancer | History of malignancy | 1 | [
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NCT02131467 | 13:30:chronic_disease | Significant renal dysfunction | 1 | [
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NCT02135588 | 1:17:chronic_disease,32:38:chronic_disease,43:55:chronic_disease | Major hemorrhage, coincidental stroke, or major trauma | 1 | [
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NCT02327403 | 14:41:chronic_disease | active acute antibody-mediated rejection | 1 | [
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NCT02315196 | ,,,58:71:cancer,,,,,,,129:155:treatment,159:200:treatment,,246:251:cancer,,318:328:treatment | Women with previously untreated, unilateral stage II-III breast cancer, ER/PgR/HER2 negative (ER =< 5%, PgR =< 5%, HER2 0-1+ by immunohistochemistry [IHC] or fluorescence in situ hybridization [FISH] =< 2.0); if clinically negative lymph nodes, tumor size should be minimum 1.0 cm and identifiable under office-based ultrasound guidance | 1 | [
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NCT02520778 | ,95:102:treatment,104:115:treatment,119:137:treatment,171:186:treatment,188:196:treatment,198:209:treatment,211:233:treatment,288:296:treatment,298:309:treatment,311:333:treatment | currently receiving (or unable to stop use at least 1 week prior to receiving the 1st dose of AZD9291) medications or herbal supplements known to be potent inhibitors of cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8) and potent inhibitors or inducers of cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) | 1 | [
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NCT02308709 | 1:19:treatment,7:19:treatment,24:39:cancer,49:59:cancer | Prior radiotherapy for thoracic cancer or other malignancy leading to any overlap of planned radiotherapy fields | 1 | [
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NCT02496663 | 6:12:treatment,16:21:cancer,49:58:treatment,60:69:treatment,73:81:treatment,,154:163:treatment, | have biopsy of tumor taken after progression on erlotinib, gefitinib or afatinib which must be EGFR-T790M negative confirmed by central testing prior to treatment (if EGFR-T790M status is unknown, patients may consent for trial and for biopsy and testing for EGFR T790M will be performed as part of initial biopsy for trial) | 1 | [
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NCT02398773 | 41:67:treatment,77:87:treatment,91:102:treatment,108:129:treatment,145:162:treatment | Patient must NOT be planning to receive molecular targeted therapy (such as everolimus or palbociclib) nor HER2 directed therapy in addition to endocrine therapy | 1 | [
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NCT03006302 | 5:23:chronic_disease,35:62:chronic_disease,67:89:chronic_disease, | New pulmonary embolism, extremity deep venous thromboembolism, or portal vein thrombosis within 2 months of study enrollment | 1 | [
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NCT02406599 | 1:30:treatment | Neo-adjuvant systemic therapy | 1 | [
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NCT01952730 | ,41:57:cancer | Greater than 1 month since resection of liver metastasis for vaccine production | 1 | [
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NCT01515527 | 26:29:cancer,45:48:cancer,82:95:treatment | Patients with history of MDS transformed to AML are eligible regardless of their prior therapy for MDS provided | 1 | [
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NCT03035474 | 22:30:chronic_disease | Hospitalizations for acute HF will be determined by local clinician-investigators | 1 | [
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NCT02140255 | 11:14:chronic_disease, | No plasma HIV RNA detected by testing performed at the local CLIA-certified (US sites) or VQA-certified (non-US sites) laboratory, after criteria above have been confirmed, with specimen collection for the assay within 14 days prior to Step 3 Entry | 1 | [
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NCT03175978 | 15:44:chronic_disease | Patients with active extramedullary disease | 1 | [
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NCT00967577 | 13:35:treatment,28:35:treatment,39:48:treatment,,123:139:treatment | Subjects on bisphosphonate therapy or denosumab must be on a stable dose and must have started therapy > 4 weeks prior to protocol therapy | 1 | [
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NCT02647723 | 8:32:treatment | Use of psychotropic medications | 1 | [
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NCT00258427 | 1:26:cancer | Biallelic BRCA2 mutations | 1 | [
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NCT02273375 | 18:28:cancer,33:59:cancer,61:87:cancer,91:134:cancer | A combination of small cell and non-small cell lung cancer, pulmonary carcinoid tumour or large-cell neuroendocrine carcinoma (LCNEC) | 1 | [
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NCT02865135 | 1:18:cancer | carcinoma in situ of the cervix or bladder | 1 | [
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NCT02489045 | 15:39:chronic_disease | Patients with congenital heart defects | 1 | [
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NCT02341235 | 13:31:chronic_disease | Evidence of disease recurrence | 1 | [
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NCT02495415 | 28:53:treatment, | Participation in any other investigational treatment within the 6 weeks prior to enrollment or concurrent with this study | 1 | [
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NCT00085982 | 14:27:chronic_disease | Syndromes of lipodystrophy are similar, but we already have approval to treat this group of patients | 1 | [
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NCT01992861 | 32:62:treatment,38:54:treatment,82:87:cancer | Patients who have received any prior pelvic radiation therapy in the area of the tumor that precludes the delivery of a curative dose of pelvic radiation | 1 | [
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NCT02249039 | 38:50:treatment | Any infant or child who is receiving ECMO therapy | 1 | [
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NCT02383979 | 15:34:treatment | scheduled for elective amputation | 1 | [
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NCT02311361 | 45:57:treatment,59:71:treatment,76:89:treatment, | Patients must not have had standard of care chemotherapy, radiotherapy, or major surgery within the last 2 weeks prior to entering the study | 1 | [
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NCT03185208 | 1:26:chronic_disease | Major psychiatric illness | 1 | [
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NCT02272998 | 16:32:chronic_disease | Symptomatic or active infection | 1 | [
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NCT02687906 | 43:65:allergy_name | Known significant hypersensitivity to any beta-lactam antibiotic | 1 | [
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NCT03034811 | 1:10:chronic_disease,12:18:chronic_disease,24:37:chronic_disease | Infection, sepsis, and osteomyelitis | 1 | [
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NCT00357565 | 11:41:chronic_disease | Preceding myelodysplastic syndrome (MDS) | 1 | [
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NCT00594217 | 25:33:chronic_disease,,,, | A previous diagnosis of diabetes, a fasting glucose ≥ 126 mg/dl, or a hemoglobin A1c > 6.5% | 1 | [
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NCT02169089 | 7:27:cancer | cured squamous cell cancer | 1 | [
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NCT02008656 | 31:41:cancer,45:70:cancer,82:97:cancer | except for adequately treated basal cell or squamous cell skin cancer or in situ cervical cancer | 1 | [
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NCT02503358 | 96:99:cancer, | Measurable disease as defined by RECIST v1.1 criteria. Baseline measurements and evaluation of ALL sites of disease must be obtained within 4 weeks prior to Enrollment | 1 | [
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NCT01880567 | 1:22:treatment | platelet transfusions | 1 | [
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NCT01703949 | 7:41:chronic_disease,45:56:chronic_disease,77:125:chronic_disease | Known human immunodeficiency virus (HIV) or hepatitis B positivity or prior progressive multifocal leukoencephalopathy (PML) | 1 | [
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NCT02964182 | 1:10:treatment | Bupropion | 1 | [
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NCT02543983 | 60:75:chronic_disease | For participants who still experience the effects of their suicide attempt, i.e. someone who overdosed is significantly drowsy or confused, the consenting process will occur after the patient has improved from the effects | 1 | [
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NCT02688309 | 35:65:chronic_disease,145:180:chronic_disease,182:201:chronic_disease,204:212:chronic_disease,214:223:chronic_disease,225:249:chronic_disease,255:270:chronic_disease | Patients with active or suspected ocular or periocular infection, including most viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, mycobacterial infections, and fungal diseases | 1 | [
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NCT02203695 | 20:37:chronic_disease,68:75:chronic_disease,77:86:chronic_disease,88:106:chronic_disease,110:130:chronic_disease,148:158:chronic_disease,170:173:chronic_disease,175:188:chronic_disease | Serious concurrent medical illnesses (including uncontrolled major cardiac, pulmonary, Child-Pugh C liver or psychiatric diseases) or active major infections (including HIV, Hepatitis A-C) | 1 | [
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NCT01625234 | 71:104:allergy_name,112:122:allergy_name,134:160:allergy_name | Patients with a known allergy or delayed hypersensitivity reaction to drugs chemically related to X-396 (e.g., crizotinib) or to the active ingredient of X-396 | 1 | [
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NCT01877382 | 1:28:treatment,32:43:treatment,,72:86:treatment | treatment with nitrosoureas or mitomycin C within 6 weeks before study drug treatment | 1 | [
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NCT01900093 | 14:25:chronic_disease,27:53:chronic_disease,55:76:chronic_disease,78:102:chronic_disease,124:136:chronic_disease | Diagnosis of scleroderma, systemic fungal infections, ocular herpes simplex, congestive heart failure, and/or uncontrolled hypertension, and/or any clinically relevant medical disease that would put the patient at risk by participating in the study | 1 | [
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