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NCT02440815 | 42:52:treatment | Acute or uncontrolled medical illness or medication use impacting cognitive function | 1 | [
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NCT01891812 | 36:39:treatment | any contraindications to receiving N2O | 1 | [
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NCT01804634 | 1:25:cancer | Metastatic Ewing Sarcoma | 1 | [
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NCT01581749 | 23:46:cancer, | histologically proven prostate adenocarcinoma within 1 year of enrollment | 1 | [
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NCT02140554 | 35:49:treatment | patients on prophylactic doses of anticoagulants | 1 | [
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NCT02076906 | 18:31:treatment,33:52:treatment,56:63:treatment | The last dose of immunotherapy (monoclonal antibody or vaccine) | 1 | [
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NCT02770547 | 1:4:chronic_disease | HIV positive | 1 | [
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NCT02911467 | ,,29:38:chronic_disease, | bilirubin <1.5x ULN (unless Gilbert's is suspected in which case total bilirubin < 3 x ULN) | 1 | [
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NCT02643381 | 13:36:treatment | who require endotracheal intubation without sedative medication | 1 | [
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NCT01306045 | 23:36:treatment,38:50:treatment,54:66:treatment,, | Patients who have had major surgery, chemotherapy or radiotherapy within 2 weeks prior to entering the study or those who have not recovered from adverse events due to agents administered more than 2 weeks earlier | 1 | [
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NCT02178709 | 43:55:treatment,59:73:treatment,82:91:treatment,93:106:treatment,108:121:treatment,123:131:treatment,136:145:treatment | Unable or unwilling to discontinue use of ketoconazole or St John's wort. Use of phenytoin, carbamazepine, phenobarbital, rifampin and rifabutin is discouraged, but not contraindicated | 1 | [
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NCT02582957 | 32:62:treatment | Lack of availability of Dräger Evita Infinity V500 ventilator as this is the only ventilator capable of delivering sigh breaths as described in the protocol | 1 | [
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NCT02587598 | 20:33:treatment | Prior receipt of a PIM inhibitor | 1 | [
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NCT01220583 | 4:31:treatment,35:52:treatment,57:82:cancer | No prior systemic chemotherapy or radiation therapy for salivary gland malignancy | 1 | [
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NCT01904136 | 1:24:chronic_disease | Uncontrolled infections; principal investigator (PI) is the final arbiter of this criterion | 1 | [
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NCT03079297 | 1:25:chronic_disease | Psychiatric co-morbidity posing safety risk | 1 | [
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NCT03029806 | 8:15:treatment | Recent steroid use (injected, inhaled, oral) | 1 | [
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NCT01943851 | ,43:67:chronic_disease | History or evidence of current >=Class II congestive heart failure as defined by New York Heart Association (NYHA) | 1 | [
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NCT01773707 | 18:38:chronic_disease | Have evidence of active EBV infection | 1 | [
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NCT02746458 | 1:12:treatment | Skin grafts in which all bleeding points must be readily distinguished | 1 | [
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NCT02128906 | 24:36:treatment | breast feeding because chemotherapy | 1 | [
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NCT02546583 | 18:63:treatment,,74:88:treatment,,102:112:treatment,117:126:treatment | Use of high dose mineralocorticoid receptor antagonist therapy (>50mg of spironolactone or >100mg of eplerenone) or amiloride | 1 | [
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NCT02374333 | 1:4:chronic_disease | HIV infection | 1 | [
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NCT02589522 | ,,73:82:treatment | Life expectance of greater than two months to allow completion of study treatment and assessment of dose-limiting toxicity | 1 | [
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NCT02159027 | 1:18:chronic_disease,29:40:chronic_disease,42:51:chronic_disease,57:76:chronic_disease,81:97:chronic_disease,128:136:chronic_disease,140:162:chronic_disease,206:218:treatment,222:240:treatment | Chronic illnesses including hematologic, pulmonary, and autoimmune diseases and endocrinopathies, except for stable controlled diabetes or cardiovascular disease in the view of the investigator and stable testosterone or thyroid medication use | 1 | [
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NCT02366819 | 14:42:treatment | Eligible for surgery with curative intent | 1 | [
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NCT01896999 | 46:58:treatment | Patients must have relapsed after first line chemotherapy | 1 | [
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NCT02535533 | 21:41:treatment | 3 days wash out for palliative radiation | 1 | [
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NCT03112603 | 16:62:treatment | Have undergone allogeneic stem cell transplantation (alloSCT) from any donor source (matched unrelated donor, sibling, haplo-identical) using bone marrow, peripheral blood stem cells, or cord blood | 1 | [
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NCT02138617 | 16:38:treatment,,72:79:treatment,82:93:treatment | placement of a vascular access device, within 7 days prior to Day 1 of FOLFIRI + bevacizumab initiation | 1 | [
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NCT02564978 | ,,,,,,377:405:treatment | Any female participant of childbearing potential (see Appendix 1 for definition) and any male participant able to father children must have (or have a partner who has) had a hysterectomy or vasectomy, be completely abstinent* from intercourse or must agree to practice two acceptable methods of contraception throughout the course of the study and for at least one week after investigational product (IP) discontinuation | 1 | [
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NCT02541903 | 21:31:cancer, | effectively treated malignancy that has been in remission for more than 3 years and is considered to be cured | 1 | [
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NCT02532452 | 25:35:cancer | Uncontrolled relapse of malignancy | 1 | [
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NCT01473628 | 37:58:allergy_name | No prior known allergic reaction to monoclonal antibodies | 1 | [
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NCT02522715 | 23:34:treatment | may not have received cabazitaxel in the past | 1 | [
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NCT01670877 | ,122:146:chronic_disease | Testing for LVEF is not required for pre-registration, but patient must not have a recent LVEF < LLN or have symptoms of congestive heart failure | 1 | [
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NCT02592551 | 12:24:treatment | history of hysterectomy | 1 | [
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NCT01572480 | 12:25:chronic_disease | Absence of hypercalcemia | 1 | [
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NCT03121352 | 50:59:chronic_disease | Patients with evidence of active, non-infectious pneumonia | 1 | [
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NCT03116997 | ,,35:49:treatment | INR > 1.5 (except for patients on anticoagulants) | 1 | [
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NCT02031250 | 1:30:treatment | Prior head and neck radiation | 1 | [
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NCT02562755 | 1:14:cancer | Bulky disease patients | 1 | [
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NCT01773707 | 28:43:chronic_disease,45:49:chronic_disease,51:63:chronic_disease,68:93:chronic_disease,103:114:cancer,116:126:cancer,131:147:chronic_disease | These include pre-existing cardiac disease, COPD, neurological, or blood count abnormalities (such as lymphopenia, leukopenia, or thrombocytopenia) | 1 | [
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NCT02465268 | 7:23:chronic_disease,27:52:chronic_disease | Known active infection or immunosuppressive disease | 1 | [
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NCT01804634 | 14:19:chronic_disease,21:30:chronic_disease,35:52:chronic_disease | Uncontrolled viral, bacterial, or fungal infections | 1 | [
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NCT02803359 | 12:25:allergy_name | Allergy to Oxymetazoline | 1 | [
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NCT02390752 | 30:33:chronic_disease | A first-degree relative with NF1 | 1 | [
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NCT02128802 | 1:10:chronic_disease | Cirrhosis | 1 | [
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NCT03136029 | 1:33:chronic_disease | Sleep-related Breathing Disorder | 1 | [
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NCT02234934 | 63:83:treatment | there is deemed to be an unacceptable risk associated with an allogeneic procedure | 1 | [
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NCT02092324 | 24:34:cancer,,88:110:cancer,148:171:cancer,197:214:cancer,219:245:cancer | Subjects with invasive malignancy over the previous 2 years except treated early stage carcinomas of the skin, completely resected intraepithelial carcinoma of the cervix, and completely resected papillary thyroid and follicular thyroid cancers | 1 | [
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NCT02988960 | 55:74:treatment | In addition, participants must have received only one prior immunotherapy | 1 | [
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NCT01990209 | 102:114:cancer | Patients must have MBC that is measurable or evaluable as defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 criteria | 1 | [
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NCT01419561 | 87:90:chronic_disease | Any abnormality that would be scored as NCI CTC Grade 4 toxicity that is unrelated to HIV, its treatment | 1 | [
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NCT02423772 | 65:78:chronic_disease,80:99:chronic_disease,101:110:chronic_disease,114:136:chronic_disease | Meet diagnostic criteria for a current or past DSM diagnosis of schizophrenia, delusional disorder, psychotic or dissociative disorders | 1 | [
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NCT02851407 | 13:27:chronic_disease, | Patient has acute bleeding that is clinically significant within 24 hours before the start of study treatment | 1 | [
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NCT02498613 | 104:127:treatment | Any condition that, in the opinion of the treating investigator would interfere with evaluation of the investigational product or interpretation of subject safety or study results | 1 | [
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NCT02423863 | 115:124:treatment | Serious concurrent infection or medical illness, which would jeopardize the ability of the patient to receive the treatment outlined in this protocol with reasonable safety | 1 | [
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NCT02335242 | 19:32:treatment,36:49:treatment,59:61:chronic_disease,115:124:treatment,135:145:treatment | Has had extensive prior surgery or sclerotherapy to treat LM such that scarring may interfere with evaluation and treatment effect of sildenafil | 1 | [
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NCT02911831 | 21:48:chronic_disease,65:80:chronic_disease,92:114:chronic_disease,118:136:chronic_disease | Patients with known bleeding/clotting disorders or a history of thromboembolism (including deep venous thrombosis or pulmonary embolism) | 1 | [
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NCT01037790 | 74:87:treatment, | The subject has not recovered from clinically-meaningful toxicity due to prior therapy (i.e., back to baseline or Grade ≤ 1) | 1 | [
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NCT02487797 | ,35:55:chronic_disease, | Diagnosed with at least 6 regular uterine contractions in an observation period of no more than 60 minutes | 1 | [
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NCT02076906 | 42:53:cancer | Radiographically evaluable or measurable solid tumor target lesion(s) | 1 | [
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NCT02043548 | 12:20:chronic_disease,131:146:treatment,,203:225:treatment,229:251:treatment,258:270:treatment,272:284:treatment,286:298:treatment,300:310:treatment,312:333:treatment,335:351:treatment,353:357:treatment,359:374:treatment,380:389:treatment | Refractory myositis patients are defined (see Section 3.1.1) as having failed (or considered intolerant to) an adequate course of glucocorticoids or having failed glucocorticoids and at least one other immunosuppressive (IS) or immunomodulatory agent (e.g. methotrexate, azathioprine, cyclosporine, tacrolimus, mycophenolate mofetil, cyclophosphamide, IVIg, anti-TNF agents, and rituximab) | 1 | [
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NCT02679560 | 12:19:chronic_disease,12:28:chronic_disease,59:83:chronic_disease | History of seizure disorder, recent seizure or a document intra-cranial hemorrhage | 1 | [
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NCT01595529 | 16:24:treatment | A child with a catheter-associated UTI | 1 | [
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NCT00670358 | ,,,,63:71:cancer | AST ≤ 3 times ULN (5 times ULN if direct liver involvement by lymphoma) | 1 | [
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NCT02357849 | 9:18:chronic_disease | current psychosis (any positive symptom SOPS score of 6, i.e., extreme) | 1 | [
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NCT02932280 | 1:9:cancer, | Leukemia patients must have >10% blasts (or blast equivalent) in the bone marrow | 1 | [
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NCT02003222 | 33:55:chronic_disease | Patient must not have an active uncontrolled infection | 1 | [
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NCT01978509 | 1:14:chronic_disease | Toxic colitis | 1 | [
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NCT03011684 | 19:31:treatment | Has not yet begun chemotherapy | 1 | [
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NCT02339948 | ,32:36:treatment, | Prostate volume as assessed by TRUS > 60 cc | 1 | [
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NCT02221830 | 14:26:chronic_disease,,,,,,,,,,,, | diagnosis of preeclampsia (PE defined using standard definitions based on the ACOG bulletin and the NIH Working Group on High Blood Pressure in Pregnancy (i.e., a systolic blood pressure greater than 140 mm Hg or a diastolic blood pressure greater than 90 mm Hg on at least 2 occasions at least 6 hours apart after 20 weeks gestation and proteinuria of > 300mg per 24 hour period or > 1+ on dipstick) | 1 | [
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NCT02188745 | 7:18:chronic_disease, | Known CNS disease, unless clinically stable for ≥ 3 months | 1 | [
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NCT01993810 | 53:79:cancer | Histologically or cytologically proven diagnosis of non-small cell lung cancer | 1 | [
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NCT01787409 | 50:69:treatment | patient is permitted to participate in any other therapeutic therapy for their disease as long as it does not concern vitamin D | 1 | [
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NCT02404155 | 9:36:cancer | Current treated or untreated cancer | 1 | [
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NCT02474199 | ,27:37:treatment | Be 36 months or more post-transplant | 1 | [
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NCT01542879 | 58:72:allergy_name | patients with a positive history of allergic reaction to iron compounds or other severe allergic reactions | 1 | [
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NCT01050855 | 1:76:chronic_disease | Immunodysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome | 1 | [
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NCT02791646 | 14:27:cancer, | diagnosis of breast cancer (initial or recurrence) within the last two years | 1 | [
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NCT02776761 | 12:37:chronic_disease | history of severe allergic reactions | 1 | [
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NCT02365467 | 51:68:allergy_name | Subject has a known allergy or intolerance to the device components | 1 | [
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NCT02355535 | 1:8:cancer | Gliomas | 1 | [
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NCT03120728 | 1:29:chronic_disease | systemic lupus erythematosus with positive antiphospholipid antibodies | 1 | [
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NCT01822522 | 1:12:treatment,14:28:treatment,30:42:treatment,44:57:treatment,59:73:treatment | Antibiotics: clarithromycin, erythromycin, telithromycin, troleandomycin | 1 | [
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NCT01787682 | 13:18:chronic_disease, | Presence of fever within the last 3 days | 1 | [
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NCT01895777 | 1:7:chronic_disease,, | Anemia (hemoglobin < 80g/L) | 1 | [
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NCT02095678 | 39:75:allergy_name | Known history of allergic reaction to Magnetic Resonance contrast material | 1 | [
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NCT01951885 | 1:29:cancer | Acute lymphoblastic leukemia | 1 | [
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NCT01495637 | 20:29:treatment | Persistence (after treatment) of any of the following in the PICU before enrollment: | 1 | [
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Subsets and Splits