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[Transformed migraine--chronic daily headache]. | ihydroergotamine can help patients going through a withdrawal regime. | 10667127 | [
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[Miniinvasive plate osteosynthesis of distal tibial fractures]. | The end result after open reduction and internal fixation in distal leg fractures is jeopardized by soft tissue complications. Functional conservative treatment of the same type of fractures often results in delayed and non-union; malunion or non-optimal functional result concerning ankle mobility. Mini-invasive plateosteosynthesis was performed in ten patients with sustained juxta or intra-articular fractures of the distal tibia. In all patients; stable osteo-fixation could be achieved and soft tissue comp | 10667128 | [
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[Miniinvasive plate osteosynthesis of distal tibial fractures]. | lications did not affect the final result in any of the patients. Mini-invasive plateosteosynthesis seems to be a good treatment alternative in extra- or intraarticular fractures of the distal leg. | 10667128 | [
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[Low molecular heparin in a pregnant women with heart valve prosthesis]. | Women with a prosthetic heart valve who wish to bear a child face a difficult choice. Continued medication with warfarin during pregnancy will offer her a reasonable good protection against thrombosis; but carries a considerable risk of teratogenic effects. Subcutaneously administered heparin is an alternative to warfarin. Standard (unfractionated) heparin has not offered sufficient protection against valve thrombosis; which may be a life-threatening complication. We were contacted by a woman who wished to | 10667129 | [
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[Low molecular heparin in a pregnant women with heart valve prosthesis]. | become pregnant and who did not want to use warfarin if this implied a risk for the foetus. We followed a protocol using low molecular weight heparin in rather high doses. The dose was adjusted according to the results of blood test controls; which confirmed increased need for anticoagulation as the pregnancy evolved. Serial eccocardiography excluded valve thrombosis. The woman needed psychological support from her general practitioner. No complications occurred; and she gave birth to a normal child. We des | 10667129 | [
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[Low molecular heparin in a pregnant women with heart valve prosthesis]. | cribe the various alternatives for anticoagulant treatment in pregnant women with mechanical heart valves. The choice of anticoagulant regimen and their consequences must be thoroughly discussed with the woman. | 10667129 | [
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[Myelomatosis and low level of vitamin B12]. | Many patients with multiple myeloma tend to have low serum cobalamin. The cause of this remains unclear. The important issue is whether cobalamin therapy should be used or not. We describe one case of megaloblastic erythropoiesis and multiple myeloma; and refer to some of the few studies describing the subject. Most of the patients with multiple myeloma are elderly; and the frequency of hypo- and achlorhydria is therefore increased. It has been demonstrated that cobalamin uptake and consumption is higher in | 10667130 | [
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[Myelomatosis and low level of vitamin B12]. | myeloma cells than in normal bone marrow cells; and that cobalamin may be required for paraprotein synthesis. These facts may suggest that patients with multiple myeloma are more vulnerable to developing megaloblastic anemia than others. Our patient received cobalamin therapy in addition to cytostatic therapy for multiple myeloma without complications. However; we cannot exclude that cobalamin therapy may accelerate multiple myeloma; this should be considered when such therapy is given. However; accurate g | 10667130 | [
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[Why is dioxin harmful?]. | The scandal in Belgium last spring has drawn attention to the environmental hazards of dioxins. Previous production of pesticides and widespread combustion of organic material in the presence of chloride have lead to environmental accumulation of these toxicants; which more precisely are termed polychlorinated dibenzo-p-dioxins and dibenzofurans. Their very long biological half-lives in combination with detectable biological effects at very low concentrations have caused health concerns. Chloracne is the on | 10667131 | [
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[Why is dioxin harmful?]. | ly well documented health effect in man; but there are experimental evidence for carcinogenic; teratogenic; reproductive and immunosuppressive effects. In this presentation we review current knowledge about the cellular effects of dioxins. Dioxins bind to and exert their effects through the cytoplasmic aryl hydrocarbon receptor; which acts as a transcription factor and regulates a number of cytokines and microsomal enzymes. Furthermore; dioxins interfere with hormonal signalling; and anti-oestrogenic effect | 10667131 | [
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[Why is dioxin harmful?]. | s; vitamin A inhibition and thyroxin mimicry have been reported. Recently; effects on intracellular growth factor signalling have been demonstrated. Dioxins inhibit epidermal growth factor receptor; activate protein kinase C and other intracellular signal transducers; and activate transcription factors. As overall understanding of their cellular mechanisms of toxicity is lacking; we do not possess a complete basis for estimating the adverse health effects of this group of environmental toxicants. | 10667131 | [
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[Assessment of gestational age using ultrasound--can the method be improved?]. | In Norway; ultrasound measurement of the fetal biparietal diameter is used to determine the date of confinement according to Eik-Nes & Grøttum's method. We aimed to evaluate the precision of this method. 8;029 women with singleton pregnancy and spontaneous vaginal delivery were arranged in groups according to gestational age at the time of the ultrasound examination. The precision of the biparietal diameter measurement for predicting the date of birth was determined for each group. An alternative method by | 10667132 | [
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[Assessment of gestational age using ultrasound--can the method be improved?]. | Altman & Chitty was also tested on the population. Eik-Nes & Grøttum's method predicts well the date of confinement if the biparietal diameter is measured at 17-20 weeks. Measurements at an earlier stage predict the date of birth with less confidence; particularly during completed gestational weeks 13-16; when the mean error reaches four days. Altman & Chitty's chart seemed to perform more evenly for the various gestational ages; but was systematically shifted by 3-4 days when used on our population. Eik-Ne | 10667132 | [
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[Assessment of gestational age using ultrasound--can the method be improved?]. | s & Grøttum's chart for assessing gestational age should preferably not be used before 17 weeks of gestation. Introducing new charts based on a different population is not a good option. New charts based on a Norwegian population are needed. | 10667132 | [
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[Internet and the physician-patient relationship--from "thank you" to "why"?]. | The combination of modern information technology and an increasing awareness if consumer rights in the general population has lead to more demanding patients and new challenges for doctors. By using a questionnaire we explored the extent to which doctors feel that their clinical work is influenced by quality-demanding and well-informed patients; and how the internet influences the communication between doctor and patient. A representative sample of 1;276 Norwegian doctors doing clinical work responded to th | 10667133 | [
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[Internet and the physician-patient relationship--from "thank you" to "why"?]. | e survey. A great majority of the doctors expressed that "the informed patient" is becoming an integral part of their regular workday. Three out of four Norwegian doctors had experience with patients bringing internet information to the consultation setting. Most of these doctors found this natural and unobtrusive; a few felt it influenced the doctor-patient relationship in a negative way; while one out of every four doctors found meeting "the informed patient" a positive challenge. One out of seven doctors | 10667133 | [
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[Internet and the physician-patient relationship--from "thank you" to "why"?]. | with e-mail access sporadically receives electronic mail from their patients; a few doctors get such messages often. So far Norwegian doctors are of the opinion that the new information technology has not introduced major changes or created unexpected difficulties in the doctor-patient relationship. | 10667133 | [
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[The use of Internet among Norwegian physicians]. | Access to the Internet increases rapidly; also among physicians. Little is known; however; of to what extent this tool is actually used among various groups of medical professionals; and how it compares to the use of more traditional ways of professional development such as reading of medical literature or participation in continuing medical education (CME) activities. In December of 1998; a 10% random sample of all Norwegian doctors; 1;646 in all; were mailed a questionnaire regarding their use of the Inte | 10667134 | [
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[The use of Internet among Norwegian physicians]. | rnet. 78% responded. 72% of Norwegian doctors had Internet access; 24% respectively had access either at work; at home or at both places. Doctors with access both at work and at home used the Internet significantly more often and found it of greater professional value than did the other groups. A smaller proportion of general practitioners than of other groups in the profession; had access. About half (48%) of Norwegian doctors use the Internet in a professional context. Research-oriented; male doctors; 30- | 10667134 | [
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[The use of Internet among Norwegian physicians]. | 49 years of age; indicated the highest activity on the net. Doctors using the Internet professionally had longer working hours; read more medical literature and participated more often in CME activities than did non-users. With its universal accessibility; the Internet has been seen as a major force in making medical knowledge available to all doctors. This is not yet the case; for the time being; it appears that the net widens the gap between doctors who actively seek new professional knowledge and those w | 10667134 | [
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[Teleradiology--an effective agent for solidarity of health politics?]. | nan | 10667135 | [
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[How can we justify scientific research?]. | The purpose and goal of scientific research have always been of concern to philosophers and ethicists. This concern is closely linked to the values that have justified scientific research. This paper takes a closer look at these values: professional personal fulfillment; social utility; and methodological norms such as value neutrality; openness and autonomy. These values originated in different historical epochs; however; they are still of great importance; e.g. in setting research priorities. | 10667136 | [
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[Medicine with a human face--a scientific philosophic reflection]. | The essay deals with the relationship between the scientific and humanistic social scientific aspects of medical concept formation and science. The first part focuses on methodological differences associated with the two forms of knowledge; emphasizing the distinction between quantitative and qualitative methods. The differences are traced back to type of phenomenon or object researched. On the basis of the special character of human beings and their illnesses it is then argued that scientific medicine nece | 10667137 | [
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[Medicine with a human face--a scientific philosophic reflection]. | ssarily will have to transcend the divide between the natural sciences on the one hand and the humanities and social sciences (the "human sciences") on the other. The unity in medicine is tied to its practice--the art of medicine as carried on in the clinical meeting between doctor and patient. | 10667137 | [
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[Reconsiliation, redemption and growth--a different perspective on the euthanasia debate]. | nan | 10667138 | [
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[The infected artificial hip joint: possibilities, follow-up and results of treatment]. | Infections after total hip replacement are still a severe problem. With current therapies they can be managed successfully. In the present study we investigated 38 patients who were treated in our clinic because of infected total hip arthroplasties. All patients had a minimal follow-up of two years. The three main therapeutical forms are explained: the revision without removal of the prosthesis; the one-stage exchange and the two-stage exchange. 35 of the 38 patients could be healed within the observation p | 10667145 | [
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[The infected artificial hip joint: possibilities, follow-up and results of treatment]. | eriod (from 1984-1996). Two patients died in the postoperative period from cardiopulmonary diseases. One patient could not be healed and has still an ongoing infection. The success rate was 92%; with good clinical results regarding pain; and walking ability. For the patient; the treatment of an infection can be very perturbing. With the new therapeutical forms the strain for the patient can be decreased. The type and duration of the therapy before definitive treatment has no influence on the success rate. I | 10667145 | [
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[The infected artificial hip joint: possibilities, follow-up and results of treatment]. | n cases with a previous long-term therapy; a more complex treatment may be necessary. The treatment should be performed in an experienced clinic. The general practitioner plays an important part in the diagnosis and after care. An adequate treatment can be offered to nearly every patient with an infected total hip arthroplasty. This also applies to patients with long-term infection and chronic fistulation. | 10667145 | [
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[Swallowed dental prosthesis]. | A 66 year old man presented at the ambulatory with acute dysphagia. Inspectorial and radiologic examination revealed a swallowed dental prosthesis. The importance of the history and the clinical and radiological examination are discussed. | 10667146 | [
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[Secondary amenorrhea with hyperprolactinemia. 23-year-old Turkish patient, chief symptom: amenorrhea]. | nan | 10667147 | [
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20th Annual meeting of the Society for Maternal-Fetal Medicine. Miami Beach, Florida, USA. January 31-February 5, 2000. Abstracts. | nan | 10667148 | [
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78th General session of the International Association for Dental Research, in conjunction with the 29th annual meeting of the American Association for Dental Research and the 24th annual meeting of the Canadian Association for Dental Research. Washington, DC, USA. April 5-8, 2000. Abstracts. | nan | 10667150 | [
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10th International Hamburg Symposium on Tumor Markers. Hamburg, Germany, 5-7 December 1999. Abstracts. | nan | 10667149 | [
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Cytologic changes in hepatocellular carcinoma after percutaneous acetic acid injection. Correlation with helical computed tomography findings. | To illustrate the cytologic features of hepatocellular carcinoma (HCC) after percutaneous acetic acid injection (PAI) and to correlate the cytologic findings with helical computed tomography (CT) findings.The study included 30 patients with 37 HCC who had undergone PAI. Baseline cytomorphology of HCC was evaluated by needle aspiration in all cases. PAI under ultrasound guidance was done every three to seven days. Upon completion of PAI; fine needle aspiration cytology was performed and followed by helical C | 10667151 | [
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Cytologic changes in hepatocellular carcinoma after percutaneous acetic acid injection. Correlation with helical computed tomography findings. | T within two weeks. The degeneration of HCC after PAI was classified into two grades. Grade 1 showed incomplete degeneration (99% of nuclear area); grade 2 showed complete degeneration or severe degeneration with cell debris or amorphous material only. The specimens were stained with Riu's method (Romanowsky system).The cytologic changes after PAI included decreased cell number; reduced cellular aggregation; degeneration of cytoplasm and nucleus; and eosinophilic or basophilic background in all tumors. In a | 10667151 | [
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Cytologic changes in hepatocellular carcinoma after percutaneous acetic acid injection. Correlation with helical computed tomography findings. | ll the 37 tumors without enhancement on helical CT; grade 2 degeneration was detected.Our results reveal that grade 2 degeneration alone; demonstrated cytologically; could indicate almost complete necrosis of HCC after PAI; probably implying no need for booster PAI. | 10667151 | [
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Immunocytochemical staining of Kupffer and endothelial cells in fine needle aspiration cytology of hepatocellular carcinoma. | To evaluate the significance of the presence of Kupffer and endothelial cells in distinguishing hepatocellular carcinoma (HCC) and adenocarcinoma (AC) on cytologic smears.Fine needle aspiration biopsies (FNABs) from 43 cases; 21 HCC and 22 AC (8 primary and 14 metastatic); were immunostained for Factor VIII and vimentin as markers for endothelial cells and Kupffer cells; respectively. Cytologic diagnosis was verified by histologic and/or clinical follow-up.Eighteen of the 21 cases (86%) of HCC and 11 (5 pri | 10667152 | [
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Immunocytochemical staining of Kupffer and endothelial cells in fine needle aspiration cytology of hepatocellular carcinoma. | mary and 6 metastatic) of 22 cases (50%) of AC showed positive immunostaining for Factor VIII (P = .02). Vimentin immunostaining was positive in 55% of HCCs and 41% of ACs (P = .74). Forty-five percent of cases of HCC showed immunostaining for both Factor VIII and vimentin; while 22% of cases of AC showed immunostaining for both Factor VIII and vimentin (P = .18).Immunocytochemical identification of endothelial cells using Factor VIII may have important diagnostic value in separating HCC from adenocarcinoma | 10667152 | [
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Immunocytochemical staining of Kupffer and endothelial cells in fine needle aspiration cytology of hepatocellular carcinoma. | s in liver FNABs. The presence of Kupffer cells labeled with vimentin has no diagnostic significance in FNAB of these tumors. | 10667152 | [
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Cytologic detection of cervical and endometrial carcinoma with other genital tract involvement. | To investigate the possibility of a correct cytologic diagnosis of cervical and endometrial carcinoma with other genital organ involvement.From uteri removed during hysterectomy due to cervical (33 cases) and endometrial (44 cases) cancer; samples were taken by cytobrush or spatula from the ectocervix; endocervix and endometrium of uteri opened longitudinally. Smears and cytosediments were stained by the Papanicolaou polychrome method. Moreover; acid beta-galactosidase activity was demonstrated in serial cy | 10667153 | [
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Cytologic detection of cervical and endometrial carcinoma with other genital tract involvement. | tosediments by the indigogenic method of Lojda. From quenched tissue samples taken from the same sites as those for cytology; a series of cryostat sections was prepared and stained by hematoxylin and eosin or azure A; or subjected to the reaction for acid beta-galactosidase.In 17 of 33 patients with cervical cancer; the same type of cancer was also found in smears of the endocervix and endometrium. In six patients the type of cancer was different. Of 44 patients with endometrial cancer; 16 had an endocervic | 10667153 | [
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Cytologic detection of cervical and endometrial carcinoma with other genital tract involvement. | al malignancy of the same type. In seven cases the type of cancer was different. The reaction for acid beta-galactosidase helped in the differentiation between squamous (negative reaction in cancer cells) and cylindrocellular (positive reaction) cancer in cytologic preparations.Before treatment; it is necessary to determine if there is involvement of the endocervix in endometrial cancer and of the endometrium in cervical cancer. Routine cytologic examination supplemented by the reaction for acid beta-galact | 10667153 | [
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Cytologic detection of cervical and endometrial carcinoma with other genital tract involvement. | osidase proved to be useful for this purpose. | 10667153 | [
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Cytologic diagnosis of axillary lymph node metastasis in breast cancer. | To compare imprint cytology with histology as a method for rapid intraoperative diagnosis of axillary lymph node metastasis in breast cancer.We evaluated imprint cytology; comparing it with histopathology. A sample of 635 axillary lymph nodes was studied by imprint cytology using both Giemsa stain and hematoxylin-eosin. The results were compared with each other and with those of histopathologic examination.The Giemsa stain method; as compared to histopathology; had 94% accuracy; 97% sensitivity; 90% specifi | 10667154 | [
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Cytologic diagnosis of axillary lymph node metastasis in breast cancer. | city and 94% positive prognostic value. The hematoxylin-eosin stain method was less accurate than the Giemsa stain method as compared to histopathology (accuracy 91%; sensitivity 96%; specificity 83% and positive prognostic value 92%).These data confirm the value of imprint cytology as a rapid; reliable method of intraoperative assessment of axillary lymph node metastasis in breast cancer. It results in better staging of the disease. It can be used intraoperatively; as an alternative to frozen section; if a | 10667154 | [
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Cytologic diagnosis of axillary lymph node metastasis in breast cancer. | pathology laboratory is not available; to exclude stage I patients from further treatment. | 10667154 | [
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Clinical impact of atypical squamous cells of undetermined significance. A cytohistologic comparison. | To assess the percentage of squamous intraepithelial lesions (SILs) in the atypical squamous cells of undetermined significance (ASCUS) cytologic diagnosis.From January 1994 to December 1995; 421 cervical Pap smears with a diagnosis of ASCUS were followed with cervical biopsies within three months. The ASCUS cytologic diagnosis was correlated with the histologic findings and stratified according to age group; previous abnormal history and cell type of ASCUS (squamoid vs. metaplastic).Histologic diagnosis sh | 10667155 | [
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Clinical impact of atypical squamous cells of undetermined significance. A cytohistologic comparison. | owed that of ASCUS diagnoses; 13% were normal; 34% were reactive; 4.8% were atypical; 43% were low grade SIL; 4% were high grade SIL; 1% were carcinoma in situ; and none were invasive lesions. The patients in the youngest group; up to 25 years; demonstrated the highest percentage of SIL. Patients with a previous abnormal gynecologic history showed a higher percentage of SIL than those without an abnormal history. SILs were observed in 51.5% of squamoid ASCUS and 36.5% of metaplastic ASCUS.Forty-eight percen | 10667155 | [
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Clinical impact of atypical squamous cells of undetermined significance. A cytohistologic comparison. | t of females having an ASCUS diagnosis on Pap smears had SIL and thus a preneoplastic lesion. The highest percentage of SIL was found in females 25 years and younger. Our findings suggest that an ASCUS diagnosis warrants ongoing follow-up. | 10667155 | [
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p53 immunohistochemistry for distinguishing reactive mesothelium from low grade ovarian carcinoma. | To determine the utility of immunohistochemical staining for p53 in cell block material for distinguishing reactive mesothelium from borderline or low grade ovarian carcinoma.Paraffin-embedded cell blocks from paracentesis and pelvic wash fluid of 44 cases of ovarian carcinoma and 20 cases containing only reactive mesothelium were immunostained for p53 using monoclonal antibody DO-7. Tumor grades ranged from borderline to high grade and were serous papillary (33); clear cell (3); mucinous (2); endometrioid | 10667156 | [
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p53 immunohistochemistry for distinguishing reactive mesothelium from low grade ovarian carcinoma. | (2); mixed serous papillary/clear cell (3) and undifferentiated (1). The three authors independently evaluated the staining; including estimation of the percentage and intensity of positive nuclear staining.A separation of positive from negative cases was seen when staining intensity was considered the critical parameter; moderate to strong staining was considered truly positive. Seventy-three percent (8/11) of borderline tumors; 80% (8/10) of low grade tumors and 65% (15/23) of intermediate to high grade t | 10667156 | [
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p53 immunohistochemistry for distinguishing reactive mesothelium from low grade ovarian carcinoma. | umors showed moderate to strong positivity. Percentage of staining was a less-reliable parameter as 25% of negative cases were positive by this assessment.p53 Immunohistochemistry; using monoclonal antibody DO-7 combined with standard morphologic evaluation; may be useful in distinguishing benign reactive mesothelium from borderline or low grade ovarian carcinoma. | 10667156 | [
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Comparison of ThinPrep and conventional preparations on fine needle aspiration cytology material. | To compare the various cytologic features on ThinPrep 2000 (TP) (Cytyc Corporation; Marlborough; Massachusetts; U.S.A.) and conventional preparation (CP) specimens from fine needle aspiration cytology (FNAC) material by a semiquantitative scoring system.In this prospective study a total of 71 consecutive cases were included. In each case; two passes were performed. The first pass was used for conventional preparations; with direct smears made and fixed immediately in 95% alcohol for Papanicolaou stain. For | 10667159 | [
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Comparison of ThinPrep and conventional preparations on fine needle aspiration cytology material. | TP preparation a second pass produced material for processing in the ThinPrep 2000. The TP and CP slides were studied independently by two observers and representative slides of CP and TP compared for cellularity; background blood and necrotic cell debris; cell architecture; informative background; presence of monolayer cells; and nuclear and cytoplasmic details by a semiquantitative scoring system. Statistical analysis was performed by Wilcoxon's signed rank test on an SPSS program (Chicago; Illinois; U.S. | 10667159 | [
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Comparison of ThinPrep and conventional preparations on fine needle aspiration cytology material. | A.).TP preparations contained adequate diagnostic cells in all cases and were tangibly superior to CP preparations concerning monolayer cells; absence of blood and necrosis; and preservation of nuclear and cytoplasmic detail (statistically significant; Wilcoxon's signed rank test; P < .000).TP preparations are superior to conventional preparations with regard to clear background; monolayer cell preparation and cell preservation. It is easier and less time consuming to screen and interpret TP preparations be | 10667159 | [
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Comparison of ThinPrep and conventional preparations on fine needle aspiration cytology material. | cause the cells are limited to smaller areas on clear backgrounds; with excellent cellular preservation. However; TP preparations are more expensive than CP and require some experience for interpretation. | 10667159 | [
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Identification of amylase crystalloids in cystic lesions of the parotid gland. | To identify alpha-amylase crystalloid formations in parotid specimens obtained by fine needle aspiration.The study concerned three cases of sialadenitis with crystalloid formation observed between 1993 and 1998. In one of these cases; transmission electron microscopy; mass spectrometry and measurement of amylase activity were used to characterize the nature of the crystalloids.Light microscopy revealed the same crystalloid structure in all three cases. In one case; where the material was saved; a biochemica | 10667160 | [
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Identification of amylase crystalloids in cystic lesions of the parotid gland. | l method made it possible to reveal high amylase activity; while protein electrophoresis and mass spectrometry were used to identify salivary alpha-amylase.Crystalloids of salivary alpha-amylase can be identified by May-Grünwald-Giemsa and Papanicolaou stain and can be rapidly confirmed through determination of amylase activity. | 10667160 | [
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Characteristics of high grade dyskaryotic cervical smears likely to be missed on rapid rescreening. | To determine if there is a type of high grade dyskaryotic cervical smear that is likely to be missed on rapid rescreening.Fifty high grade dyskaryotic smears that had originally been incorrectly reported as negative (FN) were admixed with 100 true negative smears. Each smear in the set was rapidly reviewed at least 40 times. The FN smears that were picked out on > 50% of screenings were compared with those that were passed as unremarkable on > 50% of screenings for features of the dyskaryotic cell populatio | 10667157 | [
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Characteristics of high grade dyskaryotic cervical smears likely to be missed on rapid rescreening. | n.Significant differences between the two types of FN smear were present in five aspects of the dyskaryotic cell population. A FN smear is more likely to be missed on rapid rescreening than to be selected for review if it has few dyskaryotic cells; if the dyskaryotic cells are small; with pale nuclei; and if they are scattered singly rather than in groups or syncytia.A type of severely dyskaryotic smear is likely to evade rapid rescreening as well as routine screening. This suggests that even when rapid res | 10667157 | [
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Molluscum contagiosum. A case report with fine needle aspiration cytologic diagnosis and ultrastructural features. | Cytomorphologic and ultrastructural features of molluscum contagiosum; a rare skin lesion of viral etiology; are presented.A 4-month-old female was referred for fine needle aspiration cytology of papules over the back and chest wall. A Giemsa-stained preparation of whitish material aspirated from the chest wall nodule showed numerous large; intracytoplasmic; basophilic bodies that pushed the host cell nucleus to the periphery; giving a signet-ring appearance to a few cells. A cytologic diagnosis of molluscu | 10667162 | [
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Molluscum contagiosum. A case report with fine needle aspiration cytologic diagnosis and ultrastructural features. | m contagiosum was suggested. On electron microscopy numerous intracytoplasmic viral particles were demonstrated; thus confirming the cytologic diagnosis.In clinically unsuspected cases; the cytologic diagnosis of molluscum contagiosum can be suggested by demonstrating pathognomonic molluscum bodies in aspirated material. | 10667162 | [
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Imprint cytology of core needle biopsy specimens of breast lesions. A rapid approach to detecting malignancies, with comparison of cytologic and histopathologic analyses of 173 cases. | To investigate whether imprint cytology of core needle biopsy (CNB) specimens from breast lesions is a useful method of rapidly obtaining additional diagnostic information and potentially can be used to reduce the number of biopsies needed.Cytologic analysis was performed on 173 breast lesions and compared with their histopathologic diagnoses (143 malignant and 30 benign). For imprint cytology; one CNB specimen was rolled between two slides and stained with Diff-Quik and Papanicolaou stain.The diagnostic ov | 10667161 | [
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Imprint cytology of core needle biopsy specimens of breast lesions. A rapid approach to detecting malignancies, with comparison of cytologic and histopathologic analyses of 173 cases. | erall accuracy of Diff-Quik stain (Papanicolaou stain) was 95.4% (95.9%); with a sensitivity of 96.5% (97.2%); specificity of 90% (90%); positive predictive value of 97.8% (97.8%) and negative predictive value of 84.3% (87.0%). There was no statistically significant difference between the stains. Histopathologic analysis had an overall accuracy of 97.7%; with a sensitivity of 97.2%; specificity and positive predictive value of 100% and a negative predictive value of 88.2%.Imprint cytology of CNBs is a sensi | 10667161 | [
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Imprint cytology of core needle biopsy specimens of breast lesions. A rapid approach to detecting malignancies, with comparison of cytologic and histopathologic analyses of 173 cases. | tive method of detecting malignancies in breast tumors. Diff-Quik is a rapid and reliable approach that can reduce the number of biopsies. Inadequate and suspicious cases should be evaluated based on complementary diagnostic procedures for breast lesions. | 10667161 | [
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Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy. A case report. | Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems; including lymph nodes; due to the production of antinuclear antibodies. The onset of disease is between ages 13 and 40 years; with a female preponderance.A 30-year-old female presented with right cervical lymphadenopathy and gave a history of intermittent fever and swollen joints of 2.5 years' duration. The patient was on intermittent corticosteroids. With a suggestion of t | 10667163 | [
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Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy. A case report. | uberculous lymphadenitis; the patient underwent fine needle aspiration (FNA). The diagnosis of lupus adenopathy was established by FNA of enlarged right cervical lymph nodes. Smears showed predominantly typical and atypical immunoblasts; plasma cells; occasional Reed-Sternberg-like cells and dispersed hematoxylin bodies. Smears were negative for acid-fast bacilli.When SLE patients develop lymphadenopathy; FNA cytology helps differentiate lupus adenopathy from infectious conditions; such as tuberculous adeni | 10667163 | [
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Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy. A case report. | tis; and from Kikuchi's lymphadenitis. | 10667163 | [
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Cytohistologic correlation between AGUS and biopsy-detected lesions in postmenopausal women. | To evaluate histologic findings in patients aged 50 and older whose cervical smears revealed atypical glandular cells of undetermined significance (AGUS).Computerized records spanning a four-year period were retrospectively analyzed. Thirty patients over age 50 had cervical smears interpreted as AGUS and had follow-up biopsies within 12 months following the abnormal smear. The most important histologic diagnosis from the biopsy specimens was correlated with the subcategory of the cervical smear.Five smears | 10667158 | [
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Cytohistologic correlation between AGUS and biopsy-detected lesions in postmenopausal women. | interpreted as AGUS; favor reactive; revealed abnormal histology in four cases: three endometrial polyps and one squamous carcinoma. Two smears interpreted as AGUS; favor dysplasia; revealed squamous intraepithelial lesions on biopsy in both cases. Seventeen smears interpreted as AGUS; favor endometrial cells; revealed abnormal histology in 13 cases: 1 endocervical polyp; 6 endometrial polyps; 3 endometrial hyperplasias and 3 adenomyosis. Six patients with smears interpreted as AGUS; unclassifiable; reveale | 10667158 | [
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Cytohistologic correlation between AGUS and biopsy-detected lesions in postmenopausal women. | d abnormal histology in five cases: two endocervical polyps; one endometrial polyp; one endometrial carcinoma and one ovarian carcinoma.The presence of AGUS in cervical smears from women over 50 was highly predictive of abnormal lesions detected by histologic examination. Although three cancers were detected on histologic follow-up; the most common lesions detected were endometrial polyps. | 10667158 | [
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Diagnosis of malignant mesothelioma by fine needle aspiration of a cervical lymph node. A case report. | Clinically documented distant metastases are rare in mesothelioma and tend to occur late in the course of the disease; well after the diagnosis has been made. In this instance; diagnosis was not made until a metastatic deposit was identified microscopically in the enlarged lymph node.A 65-year-old male with no definite history of occupational asbestos exposure presented with chest pain; pleural effusion and supraclavicular lymphadenopathy. Cytologic examination of material obtained by fine needle aspiration | 10667164 | [
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Diagnosis of malignant mesothelioma by fine needle aspiration of a cervical lymph node. A case report. | from his cervical lymph node revealed malignant mesothelioma. This was confirmed on histology.This was a particularly rare presentation and; as far as we are aware; was the first case in which mesothelioma was diagnosed by fine needle aspiration of a cervical lymph node. It serves to remind the pathologist that when confronted with a lymph node involved by tumor; the possibility of mesothelioma should be included in the differential diagnosis. The case also demonstrates the usefulness of fine needle aspira | 10667164 | [
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Diagnosis of malignant mesothelioma by fine needle aspiration of a cervical lymph node. A case report. | tion in the diagnosis of metastatic tumor. | 10667164 | [
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Macrophagelike vacuolated renal tubular cells in the urine of a male with osmotic nephrosis associated with intravenous immunoglobulin therapy. A case report. | Osmotic nephrosis is a form of renal tubular injury that has been found in patients treated with intravenous immunoglobulin (IVIG).A 46-year-old male who had two courses of chemotherapy for acute myelogenous leukemia was found to have refractory thrombocytopenia. After IVIG (Sandoglobulin 12%; Novartis) administration (1 g/kg) for five consecutive days; the patient became oliguric and eventually anuric on the fifth dose. Hemodialysis was initiated; and urine production was noted on day 2 of hospitalization. | 10667167 | [
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Macrophagelike vacuolated renal tubular cells in the urine of a male with osmotic nephrosis associated with intravenous immunoglobulin therapy. A case report. | Routine cytologic examination of fresh; voided urine showed numerous macrophagelike; bland epithelial cells with abundant; multivacuolated cytoplasm. Cytokeratin immunostain revealed positivity; thus confirming the epithelial origin of these cells.To our knowledge; this is the first such case reported in the English-language cytology literature. Awareness of a patient's clinical history may be helpful in avoiding an incorrect diagnosis. Urine cytology may be useful in obtaining an early diagnosis of osmoti | 10667167 | [
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Macrophagelike vacuolated renal tubular cells in the urine of a male with osmotic nephrosis associated with intravenous immunoglobulin therapy. A case report. | c nephrosis in patients receiving high-dose IVIG therapy that may eliminate the need for a renal biopsy. | 10667167 | [
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Plasmacytoma of the breast. A report of two cases diagnosed by aspiration biopsy. | Extramedullary plasmacytoma of the breast is an uncommon neoplasm; occurring either as a solitary tumor or as evidence of disseminated multiple myeloma.Two cases of plasmacytoma of the breast were diagnosed by fine needle aspiration cytology. Aspiration smears showed a dispersed population of plasmacytoid cells with eccentric nuclei; abundant cytoplasm and the characteristic paranuclear hof.The clinical; cytologic and immunophenotypic features of plasmacytoma are characteristic; and the importance of distin | 10667168 | [
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Plasmacytoma of the breast. A report of two cases diagnosed by aspiration biopsy. | guishing these neoplasms from primary mammary tumors is important to avoid unnecessary surgery. | 10667168 | [
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Scraping cytology in the diagnosis of malignant squamous neoplasms of the skin. | nan | 10667170 | [
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Imprint cytology of an intrapulmonary lymph node. | nan | 10667173 | [
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Thinking about vaginal microbicide testing. | A vaginal microbicide could slow the spread of HIV. To date; volunteers in placebo-controlled trials of candidate microbicides have been counseled to use condoms. This does not reduce the number of volunteers exposed to possible risk; but it shifts the allotment of risk from those conducting the trial to those women who may be least able to make autonomous decisions. Alternative ways of meeting the obligation to offer volunteers active benefits are explored. Counseling the use of condoms prolongs clinical t | 10667178 | [
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Thinking about vaginal microbicide testing. | rials and could cause tens of thousands of otherwise avoidable deaths. | 10667178 | [
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