metadata
license: cc-by-4.0
Citation
DepMap, Broad; Corsello, Steven; Kocak, Mustafa; Golub, Todd (2019). PRISM Repurposing 19Q4 Dataset. figshare. Dataset.
Current dataset: https://doi.org/10.6084/m9.figshare.9393293.v4
General guidance: https://doi.org/10.1101/730119
Dataset specific README: prism_repurposing_secondary
Dataset Fields
- broad_id: ID used to identify drug-batch combinations
- name: Name of the drug
- depmap_id: ID to identify a cell line
- ccle_name: ID to identify a cell line
- screen_id: ID to identify a screen
- upper_limit: Limit of the curve as dose approaches infinity
- lower_limit: Limit of the curve as dose approaches zero
- slope: Slope of the dose-response curve
- r2: Goodness of fit measure between dose-response curve and replicate viability data
- auc: Area under the dose-response curve
- ec50: Dose at the inflection point of the dose-response curve
- ic50: Dose that corresponds to a viability of 50 on the dose-response curve
- moa: Broad Repurposing Hub mechanism of action annotation
- target: Broad Repurposing Hub gene target annotation
- disease_area: Broad Repurposing Hub disease area annotation
- indication: Broad Repurposing Hub indication annotation
- smiles: Simplified Molecular Input Line Entry System (SMILES) molecular identifier
- phase: Broad Repurposing Hub latest clinical phase annotation
- passed_str_profiling: Indicator for problems identified by STR profiling