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This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings emphasise several issues of importance when conducting rare GSV association, including the need for careful cohort selection and replication strategy, accurate GSV identification, and appropriate correction for multiple testing and/or control of false discovery rate. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This highlights the importance of educational interventions and ARV treatment in HIV patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Postoperative nausea was less frequent in group R (31.4%) than in group N (53.5%) (P\u200a<\u200a0.001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In 17 (32.1%) patients, postoperative complications occurred, with 7 of them (13.2%) being serious (Clavien-Dindo 3-5). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pearson Product Moment Correlations demonstrated significant (p\u2009<\u20090.001) associations between better neuropsychological performance and higher GOSE scores. ', "Similar to the ProTECT III trial's results of the primary outcome, the secondary outcomes do not provide evidence of a neuroprotective effect of progesterone."] |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, 60 SNPs were associated (P\xa0<\xa00.05) with risk of high grade breast cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, machines and humans use a plan-until-habit scheme that simulates the environment up to a limited depth and then exploits habitual values as proxies for consequences that may arise in the future. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The aim of the current study was to examine the influence of methylenetetrahydrofolate reductase (MTHFR) gene C677T mutation and angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) variations on the risk of osteoarthritis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The low oxygen group had a significantly higher blastocyst formation rate than the atmospheric oxygen group (64.5% vs. 52.9%). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The MTHFR C677T mutation was analyzed by polymerase chain reaction (PCR) based restriction fragment length polymorphism (RFLP) methods. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The most prevalent dental arch forms were narrow tapered (50.3%) and narrow ovoid (34.2%), respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | To determine the dental arch dimensions and arch forms in a sample of Saudi orthodontic patients, to investigate the prevalence of Bolton anterior and overall tooth size discrepancies, and to compare the effect of gender on the measured parameters.\xa0 |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This result provides a potentially useful knowledge of postoperative pain characteristics in RAPN and LPN. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While homozygosity for SLC4A1Delta27 appears to be nonviable, the GYPCDeltaex3 allele is not lethal when combined with SLC4A1Delta27. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Here, we investigated the epigenetic status of the BIM locus in NPM/ALK+ anaplastic large cell lymphoma (ALCL) cell lines and in lymph node biopsies from NPM/ALK+ ALCL patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Prevalence increased with age (mass), and apparent seasonality was due to a higher proportion of older animals in spring. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Participants self-reported their usual mode of commute to work, with responses recoded into three categories: (1) multi-modal or active commuting (walking and bicycling; n = 56); (2) public transit (n = 52); and (3) private transport (n = 111). Associations between environmental characteristics and likelihood of active commuting and public transit use were modeled using logistic regression with private transport (driving alone or carpool) as the reference category, adjusting for age, gender, and household car ownership. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We conducted a cross-sectional analysis of the third wave follow-up of the Andhra Pradesh children and parents study (APCAPS) (n\u202f=\u202f5764, median age 28.8\u202fyears) in south India. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The body condition of individuals with lesions declined at the time when the lesion was first recorded, when compared to individuals without lesions, suggesting there may be an acute phase of infection during its advanced stage. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this observational cohort study, we report patient outcomes with RTX in GPA patients with pulmonary nodules who failed to achieve remission following conventional immunosuppression. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The liver metastatic CRC patients with high expression of CD133+ CD54+ (P\xa0<\xa00.001), CD133- CD54+ (P\xa0=\xa00.004), and CD133+ CD44+ CD54+ (P\xa0=\xa00.003) cellular subpopulations of CTCs had a worse survival than those patients with low expression. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Data from the Sixth Korea Youth Risk Behavior Web-based Survey (KYRBWS-VI), a cross-sectional study among 74,980 students in 800 middle schools and high schools with a response rate of 97.7%, were analyzed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Environmental attributes around participants' homes were assessed using the Neighborhood Environment Walkability Scale for India (NEWS-India). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | To test this hypothesis, 24 men and 24 women age 58 ± 2.4 yr were pretreated with leuprolide and either sex steroid (E2 in women, T in men) or placebo addback. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Disruption of this process results in inappropriate chromosome segregation and aneuploidy, and appears to contribute to cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, combining two pairs of genes improved sensitivity without compromising specificity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We sent a questionnaire to all the crematoria in the UK enquiring about the frequency, consequences and prevention of pacemaker explosions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Failure was defined as definite aseptic loosening, and the final survivorship at 8 years was 99.3% for the SL-stem, and 99.1% for the CSF-threaded cup. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Homologous blood requirements were not significantly different among the groups; postoperative hematologic values and coagulation times were also comparable. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Contrary to findings in high-income countries, the odds of active commuting were reduced with improved safety from crime (aOR =0.2, p = 0.003), aesthetics (aOR =0.2, p = 0.05), and street connectivity (aOR =0.2, p = 0.003). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Data acquisition was performed using electrocardiography-triggered, navigator-gated, inversion-recovery prepared, segmented gradient-echo sequence. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study aims to investigate relationship between ARR and primary aldosteronism in CKD patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We hypothesize that the administration of oxandrolone will improve pulmonary function in burned pediatric subjects. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Six potential factors were estimated to be associated with increased risk of hypertension including age, ethnicity, marital status, body mass index (BMI), waistline circumference, and comorbidity. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In conclusion, comparative analysis of the expression of two genes may be a simple and effective classifier for prediction of prostate cancer progression. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We retrospectively analysed data from 65 patients. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, intraoperative antifibrinolysis may not be indicated in routine cardiac surgery when other blood-saving techniques are adopted. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Sixty-one single nucleotide polymorphisms (SNPs) from 40 genes were associated (P\xa0<\xa00.05) with risk of breast cancer in a log-additive model. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These data provide evidence that serum oestradiol concentrations in post-menopausal women may have a substantial effect on breast cancer risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study supports the hypothesis that subsensory vibratory noise applied to the soles of the feet can reduce gait variability in elderly participants. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Seminal plasma HIV-1 RNA level is an important determinant of the risk of HIV-1 sexual transmission. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We conclude that, in our cohort, the immunophenotypic landscape of primary antibody deficiencies comprises a spectrum, in which some alterations are shared between all primary antibody deficiencies whereas others are only associated with common variable immunodeficiency. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Participants completed a structured questionnaire to identify sleep habits and other stroke risk factors. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Eighteen elderly recurrent fallers and 18 elderly non-fallers were recruited from the MOBILIZE Boston Study (MBS), a population-based cohort study investigating novel risk factors for falls. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Furthermore, asymptomatic relatives showed decreased levels of CD4+ recent thymic emigrants and increased central memory T cells. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We show that BIM is epigenetically silenced in cell lines and lymph node specimens and that treatment with the deacetylase inhibitor trichostatin A restores the histone acetylation, strongly upregulates BIM expression, and induces cell death. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A comprehensive early childhood vision screening program in Hawai'i utilizing automated hand-held photoscreeners may have public health value. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The immunogenicity of HBV vaccine and the effectiveness of the universal immunization strategy have been widely demonstrated. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Multivariate logistic regression and linear models were used to investigate the association between reproductive risk factors and genome wide and CpG-specific DNA methylation, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | An optimized risk score model was used to assess the risk and determine the predictive power of risk factors on hypertension. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Patients completing continuation treatment without relapse enter 52 weeks of doubleblind maintenance treatment, where those treated with WS 5570 are re-randomized to 3 x 300 mg/day WS 5570 or placebo. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further natural history studies are likely to provide information to help improve the content of psychological treatments for cannabis use. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In 535 searches, 2080 donors were requested for KIR genotyping (mean 4.3 per search); and a median of 1.8 (range, 0 to 4.5) per search were KIR typed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | TB was monitored for 2 years in wild field voles in Kielder Forest, UK. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, the prevalence of hypertension (SBP ‚â• 130 or DBP ‚â• 80 mm Hg) was also estimated according to the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) High Blood Pressure Guideline. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A total of 108 individuals provided a valid MMPI-2 between January 2007 and December 2010. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Plasma from patients and controls was incubated with renal tubular cells (RTCs) and cell death was evaluated. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings may help prioritize patients for whom the intervention is most effective. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The study was to investigate the effects of oxygen concentration at different levels for culturing pre-compaction embryos on human embryo development competence. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Despite progressing slowly, it causes severe clinical pathology and overt symptoms in its rodent host. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Lower density of fruit/vegetable vendors, and higher density of highly processed/take-away food vendors were associated with adverse cardiovascular risk profiles. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Around 2014, the clade B4/H24RxC acquired a second carbapenemase gene, blaNDM-5, on a conserved IncFII plasmid. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | DUP is a modifiable factor that if reduced can improve patient outcome and treatment response. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Data about other variables of interest were obtained from medical records. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the present study, we investigated national epidemiology of ST410 E.\xa0coli isolates from Danish patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We enrolled 11 CRS Type 5 patients from ICU and 16 healthy controls. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Postoperative complications occurred in eight patients (35%), including postoperative pneumonia (n=3) and late bronchopleural fistula (n=2). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | MATERIAL AND METHODS Fifty-three (21 female/32 male) patients who underwent elective laparoscopic total gastrectomy due to cancer were prospectively analyzed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Surgical removal of solid tumors is performed as an initial attempt to cure patients; however, surgery is often accompanied with trauma, which can promote early recurrence by provoking detachment of tumor cells into the blood stream or inducing systemic inflammation or both. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We performed cardiovascular assessments at a single clinical site on the largest prospectively studied cohort to date. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Specifically, disregulation and somatic mutation of mitotic regulators has been observed in human cancers, and overexpression of mitotic regulators is common in aggressive and late stage tumors. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Eating competence is associated with a healthy diet and could, thus, in the long term, support the prevention of type 2 diabetes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Gait variability reductions with noise were similar between the elderly recurrent fallers and elderly non-fallers. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Group 1 consisted of 12 patients who (after ventral removal of the focus of infection and autologous bone grafting) were treated by dorsal instrumentation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Participants were evaluated for their self-medication practices via 4 items |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Using a split litter design, we generated stressed mice (STR) and within litter controls (LMC) along with age-matched, untreated animals (AMC), to serve as across litter controls. |