|
--- |
|
license: cc |
|
tags: |
|
- protein |
|
- biology |
|
- botany |
|
pretty_name: GreenBeing |
|
configs: |
|
- config_name: default |
|
data_files: |
|
- split: pretraining |
|
path: "proteins_pretraining.csv" |
|
- split: finetuning |
|
path: "proteins_finetuning.csv" |
|
- split: research |
|
path: "proteins_research.csv" |
|
--- |
|
|
|
# GreenBeing Proteins dataset |
|
|
|
Proteins from UniProtKB (knowledge base), from select food crops and related species. <br/> |
|
Amino acid sequences use [IUPAC-IUB codes](https://en.wikipedia.org/wiki/FASTA_format#Sequence_representation) where letters A-Z map to amino acids. <br/> |
|
|
|
XML source from https://www.uniprot.org/help/downloads <br/> |
|
CoLab notebook: https://colab.research.google.com/drive/1M6sO0Ws6i5z9VUXIXopiOqo1OkQ7K-1g?usp=sharing |
|
|
|
## Pretraining split |
|
|
|
Amino acid sequences for **unreviewed proteins (TrEMBL)** |
|
|
|
Each row contains a species or subspecies name (for filtering), and the amino acid sequence of a protein. |
|
Large proteins are split into a new row every 8,000 letters. |
|
|
|
### Share of taxa |
|
|
|
In the pretraining split: |
|
- 31% Papilionoideae/Faboideae (soybeans, peas, pulses, peanuts) |
|
- 19% Triticeae (wheat, barley, rye, and relatives) |
|
- 17% Oryzeae (rice, wild rice, and relatives) |
|
- 12% Paniceae (most millets) |
|
- 6% Solanum (potatoes, tomatoes, other nightshades, etc.) |
|
- 5% Zea (corn/maize) |
|
- 2% Sorghum |
|
- 2% Lactuca sativa (lettuce) |
|
- 2% Capsicum (chili peppers) |
|
- 2% Cucurbita (squash, pumpkins) |
|
- 0.8% Spinacia |
|
- 0.7% Asparagus |
|
- 0.2% Beta vulgaris (beet) |
|
- 0.1% Bambusa (includes edible bamboo shoots) |
|
|
|
## Finetuning split |
|
|
|
**Reviewed proteins (Swiss-Prot)** from above taxa. Each row contains a gene name, species or subspecies, an amino acid sequence, and comments / annotations available in UniProt. |
|
|
|
A gene name may match multiple entries on UniProt from different accessions. |
|
|
|
Annotations may be empty, or may include information such as: |
|
|
|
- likely function, written in English |
|
- location inside of cell (e.g. "Subcellular locations: Vacuole") |
|
- locations in the plant (e.g. "Expressed in roots, stems") |
|
|
|
Removed PubMed reference numbers to avoid training models to hallucinate PubMed references. |
|
|
|
In the current state of plant genomics research, about half of the finetuning split are from rice and related |
|
species, a fifth are from Papilionoideae/Faboideae, and seven taxa have less than 1% each. |
|
|
|
## Research split |
|
|
|
Proteins from quinoa (~99%), cañihua, and the three species of amaranth which are currently grown for grain. |
|
|
|
Columns contain UniProt/TrEMBL gene names, species, and the amino acid sequence. |
|
Large proteins are split into a new row every 8,000 letters. |
|
|
|
## Limitations and Safety Notes |
|
|
|
Proteins and review status on UniProt are from March 29, 2024. |
|
|
|
You should at least pretrain on more than *Oryza sativa*, because its reviewed proteins are probably some of the most common/important. |
|
|
|
Understanding reviewed/unreviewed proteins: https://www.uniprot.org/help/uniprotkb_sections |
|
|
|
The reviewed sequences are often similar to unreviewed sequences from related species and accessions, and are not suitable to test predicting/infilling/completion. |
|
|
|
Species include inedible wild relatives.<br/> |
|
Some people have allergic reactions to wheat/gluten, nightshades, maize, and other crops.<br/> |
|
Chili peppers can be painfully spicy. |
|
|