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(Liver and Bile Duct) Cholangiocarcinoma

This model can additionally be run on our pathology reports platform

Credits: Dr. Lidiane Marins (Rede D’OR São Paulo, Brazil)

Introduction

This H&E cholangiocarcinoma tissue classifier was developed using transfer learning on a histology optimized version of the VGG19 CNN (DOI: 10.1038/s42256-019-0068-6) and trained to recognize cholangiocarcinoma and other surrounding tissue elements.

Annotations were carried out on batches of image tiles (dimensions: 512 x 512 px) grouped using image-based clustering (HAVOC, DOI: 10.1126/sciadv.adg1894) from 5 publicly available TCGA-CHOL H&E-stained whole slide images. Validation testing was carried out on non-overlapping cases from TCGA.

Classes

  1. Connective Tissue
  2. Demoplasia
  3. ICC
  4. Skeletal muscle
  5. Necrosis
  6. Non neoplastic liver
  7. Blank space

This information can be found in the inference.json file

Evaluation Metrics

Classifier validation can be found on the pathology reports platform

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