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Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA). The main uses are infections of the skin and pneumonia although it may be used for a variety of other infections including drug-resistant tuberculosis. It is used either by injection into a vein or by mouth.
When given for short periods, linezolid is a relatively safe antibiotic. It can be used in people of all ages and in people with liver disease or poor kidney function. Common side effects with short-term use include headache, diarrhea, rash, and nausea. Serious side effects may include serotonin syndrome, bone marrow suppression, and high blood lactate levels, particularly when used for more than two weeks. If used for longer periods it may cause nerve damage, including optic nerve damage, which may be irreversible.
As a protein synthesis inhibitor, linezolid works by suppressing bacterial protein production. This either stops growth or results in bacterial death. Although many antibiotics work this way, the exact mechanism of action of linezolid appears to be unique in that it blocks the initiation of protein production, rather than one of the later steps. As of 2014, bacterial resistance to linezolid has remained low. Linezolid is a member of the oxazolidinone class of medications.
Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. It is on the World Health Organization's List of Essential Medicines. The World Health Organization classifies linezolid as critically important for human medicine. Linezolid is available as a generic medication. | ã¢ãªããŒã ã¯ãã¢ã¹ãã«ããŒã ãšæ¯ã¹ãŠåªããç¹åŸŽãããã€ãæã£ãŠãããã¹ã¯ããŒã¹ãããçŽ2000åçããã¢ã¹ãã«ããŒã ãšæ¯ã¹ãŠãçŽ10åçãããŸãã åŸå³ãæ®ãã«ãããé«æž©ç°å¢ãé
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Calcium peroxide is a member of calcium oxides. | β-ã·ãã¹ãããŒã« (β-sitosterol) ã¯ãæ€ç©ã¹ãããŒã«ã®äžçš®ã§ãã³ã¬ã¹ãããŒã«ã«é¡äŒŒããååŠæ§é ããã€ã宀枩ã§ã¯çœè²ã§èç¶ã®åºäœã§ããã | 0 |
Nitromethane, sometimes shortened to simply "nitro", is an organic compound with the chemical formula CH3NO2. It is the simplest organic nitro compound. It is a polar liquid commonly used as a solvent in a variety of industrial applications such as in extractions, as a reaction medium, and as a cleaning solvent. As an intermediate in organic synthesis, it is used widely in the manufacture of pesticides, explosives, fibers, and coatings. Nitromethane is used as a fuel additive in various motorsports and hobbies, e.g. Top Fuel drag racing and miniature internal combustion engines in radio control, control line and free flight model aircraft. | ã¯ããã³ã¢ã«ããã (crotonaldehyde) ã¯ãäžé£œåã¢ã«ãããã«åé¡ãããææ©ååç©ã®ã²ãšã€ãIUPACåœåæ³ ã§ã¯ 2-ããããŒã« (2-butenal) ãšè¡šããããå¥åãšã㊠ãããã¬ã³ã¢ã«ããã (propionaldehyde)ãβ-ã¡ãã«ã¢ã¯ãã¬ã€ã³ (β-methylacrolein)ãã¡ãã«ãããããŒã« (methylpropenal) ãªã©ãšãåŒã°ãããCASç»é²çªå·ã¯ [4170-30-3]ã幟äœç°æ§äœãšã㊠ciså ãš transåã®äºçš®é¡ããããããããã® CASç»é²çªå·ã¯é ã« [123-73-9]ã[15798-64-8] ã§ãããåååŒã¯ C4H6Oã瀺æ§åŒã¯ CH3CH=CHCHO ã§ãããæ¯ç©åã³åç©åç· æ³ã«ããæ¯ç©ã«æå®ãããŠãããæ¶é²æ³ã«å®ãã第4é¡å±éºç© 第1ç³æ²¹é¡ã«è©²åœããã | 0 |
Butyl acetate is the acetate ester of butanol. It has a role as a metabolite. It is functionally related to a butan-1-ol. | ãã¢ãã³ïŒè±: thiamin, thiamineïŒã¯ããã¿ãã³B1ïŒè±: vitamin B1ïŒãšãåŒã°ãããã¿ãã³ã®äžã§æ°Žæº¶æ§ãã¿ãã³ã«åé¡ãããçç掻æ§ç©è³ªã§ãããæ é€çŽ ã®ã²ãšã€ããã®ã»ãããµã€ã¢ãã³ãã¢ãã€ãªã³ãšãåŒã°ããã | 0 |
Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide. | 2-ãããµããŒã«(2-hexanol, hexan-2-ol)ã¯ã2äœççŽ ã«ããããã·ã«åºã眮æãã6ççŽ ã¢ã«ã³ãŒã«ã§ãããååŠåŒã¯C6H14O or C6H13OHããããµããŒã«ã®ç°æ§äœã®äžã€ãäžæççŽ ããããããå
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Glyceric acid is a trionic acid that consists of propionic acid substituted at positions 2 and 3 by hydroxy groups. It has a role as a fundamental metabolite. It is functionally related to a propionic acid. It is a conjugate acid of a glycerate. | ã°ãªã»ãªã³é
žïŒã°ãªã»ãªã³ãããglyceric acidïŒã¯ã倩ç¶ã«ååšããäžççŽ ã®ç³é
žã§ããããšã¹ãã«ã®å Žåãã°ãªã»ã©ãŒãïŒglyceratesïŒãšãåŒã°ããã | 1 |
Buspirone is an azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position. It has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is an azaspiro compound, a member of pyrimidines, a N-arylpiperazine, a N-alkylpiperazine, a member of piperidones and an organic heteropolycyclic compound. It is a conjugate base of a buspirone(1+). | ã·ã¢ããžã³ïŒCyanidinïŒã¯ãææ©ååç©ã®äžã€ããããŠããã«ããªãŒããã©ãã¯ããªãŒããã«ãŒããªãŒããµã¯ã©ã³ãããã¯ãã³ããµã³ã¶ã·ãããŒã¬ã³ããªãŒãã¢ãµã€ããªãŒããã³ã©ãºããªãŒãªã©å€ãã®èµ€è²æ¶²æé¡ã«å«ãŸããããã®ä»ã«ããªã³ãŽãã¹ã¢ã¢ã«ãå«ãŸãããèµ€æ©è²ãç¹åŸŽçã§ããããpH > 3ã§èµ€ãpH 7-8 ã§çŽ«ãpH > 11ã§éè²ã«å€åãããã·ã¢ããžã³ã®æ¿åºŠãæã倧ããéšåã¯æå®ã®ç®ã§ãããè¿å¹Žã§ã¯ãEscherichia coliïŒå€§è
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Ethion (C9H22O4P2S4) is an organophosphate insecticide. It is known to affect the neural enzyme acetylcholinesterase and disrupt its function. | ããã¯ãã³ïŒè±èª: nonactinïŒã¯ãç°ç¶ã®ãšã¹ãã«ã®ç¯çã«å
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Sulfamide (IUPAC name: sulfuric diamide) is a compound with the chemical formula SO2(NH2)2 and structure H2NâS(=O)2âNH2. Sulfamide is produced by the reaction of sulfuryl chloride with ammonia. Sulfamide was first prepared in 1838 by the French chemist Henri Victor Regnault. | ã°ã«ã³ãŒã¹-6-ãªã³é
žïŒã°ã«ã³ãŒã¹-6-ãªã³ãããGlucose-6-phosphateãG6PïŒãšã¯ã6äœã®ççŽ ããªã³é
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Dinitrogen trioxide is a nitrogen oxide. | ã«ãã£ãããïŒRufinamideïŒã¯æãŠãããè¬ã®äžã€ã§ãããã¬ããã¯ã¹ã»ã¬ã¹ããŒçå矀ã®æ²»çã«ã€ããŠä»ã®æãŠãããè¬ãšã®äœµçšã§çšããæšãæ¿èªãããŠãããä»ã®çæ£æ§çºäœã«ã€ããŠæ¿èªãããŠããåœããããåååã€ãããã³ã
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Cloxacillin is a semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6. It has a role as an antibacterial agent and an antibacterial drug. It is a semisynthetic derivative, a penicillin allergen and a penicillin. It is functionally related to an oxacillin. It is a conjugate acid of a cloxacillin(1-). | ãšãªãã«ããŒã¹ (erythrulose) ã¯ãååŠåŒãC4H8O4ã®ã±ãããããŒã¹ã§ããããžããããã·ã¢ã»ãã³ãšæ§è³ªããã䌌ãŠãããç¡è²ãŸãã¯ããé»è²ã液äœã倩ç¶ã§ã¯ã©ãºããªãŒããªã³ãŽãªã©ã«å«ãŸããç¹ã«ãªã³ãŽã§ã¯åãå£ãè€å€ããåå ãšãªã£ãŠããã | 0 |
Pentadecane is an alkane hydrocarbon with the chemical formula C15H32. It can be monoterminally oxidized to 1-pentadecanol. | ããã¹ã¿ãã³ïŒã¢ãã³ãªã³Kãã¡ãã³ãŒã«çãšãåŒã°ããLovastatinïŒ ã¯ã¹ã¿ãã³ç³»ã®è¬å€ã®äžçš®ã§ãããè¡äžã³ã¬ã¹ãããŒã«ãäœæžããå¿è¡ç®¡çŸæ£ã®ãªã¹ã¯ãäœæžããäœçšãããã | 0 |
Acetate is a monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It is a conjugate base of an acetic acid. | ãªããè±èªã® Acetate ããã³ ethanoate ã¯é
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Camphorsulfonic acid is a sulfonic acid containing the camphorsulfonate anion. It is functionally related to a camphor. It is a conjugate acid of a camphorsulfonate anion. | ãŠããã«ãã£ãªããŒã²ã³IIIïŒUroporphyrinogen IIIïŒ ã¯ããã«ãã£ãªã³ã®çåæã«ãããŠãããããã·ã¡ãã«ãã©ã³ãããŠããã«ãã£ãªããŒã²ã³IIIã·ã³ã¿ãŒãŒïŒåæé
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Phthalic anhydride is the organic compound with the formula C6H4(CO)2O. It is the anhydride of phthalic acid. Phthalic anhydride is a principal commercial form of phthalic acid. It was the first anhydride of a dicarboxylic acid to be used commercially. This white solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year. | ã€ãªãã³ã¶ã é
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6-Hydroxymellein is a natural product found in Lachnum papyraceum, Myxotrichum stipitatum, and other organisms with data available. | ã¢ããœãŒã« ïŒè±èª: anisoleïŒãŸãã¯ã¡ããã·ãã³ãŒã³ïŒè±èª: methoxybenzeneïŒã¯ãã¢ãã¹ã®å®ã«äŒŒãå¿«ãéŠãã瀺ãææ©ååç©ã§ãå€èŠã¯ç¡è²ã®æ¶²äœããã³ãŒã³ã®æ°ŽçŽ ã1åã¡ããã·åº (âOCH3) ã«çœ®ãæããæ§é (C6H5OCH3) ãæã€ãšãŒãã«ã§ãããæ¶é²æ³ã«å®ãã第4é¡å±éºç© 第2ç³æ²¹é¡ã«è©²åœããã
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Acetylacetone is an organic compound with the chemical formula CH3âC(O)âCH3. It is classified as a 1,3-diketone. It exists in equilibrium with a tautomer CH3âC(C(âOH)âCH3. The mixture is a colorless liquid. These tautomers interconvert so rapidly under most conditions that they are treated as a single compound in most applications. Acetylacetone is a building block for the synthesis of many coordination complexes as well as heterocyclic compounds. | ãã³ã¿ã¯ããããããã³ãŒã³ïŒè±: pentachloronitrobenzeneãç¥ç§°PCNBïŒã¯ååŠåŒC6Cl5NO2ã§è¡šãããææ©ååç©ããã³ããŒã³ïŒquintozeneïŒãªã©ã®å¥åã§ãåŒã°ãããçŽç²ãªãã®ã¯ç¡è²ãçŽåºŠã®äœããã®ã¯æ·¡é»è²ã®çµæ¶ã§ãç¹ç°ãªèæ°ãããã | 0 |
Ofloxacin is a racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. It has a role as a DNA synthesis inhibitor, an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor and a topoisomerase IV inhibitor. It is a quinolone antibiotic, a fluoroquinolone antibiotic and a racemate. It contains a levofloxacin and a dextrofloxacin. | ããã ããªããŒã«ïŒBromperidolïŒã¯ãããããã§ãã³ç³»ã®æ粟ç¥ç
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Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings.
Common side effects include dry mouth, abnormally large pupils, urinary retention, constipation, and a fast heart rate. It should generally not be used in people with closed-angle glaucoma. While there is no evidence that its use during pregnancy causes birth defects, this has not been well studied so sound clinical judgment should be used. It is likely safe during breastfeeding. It is an antimuscarinic (a type of anticholinergic) that works by inhibiting the parasympathetic nervous system.
Atropine occurs naturally in a number of plants of the nightshade family, including deadly nightshade (belladonna), Jimson weed, and mandrake. It was first isolated in 1833, It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. | ãµã€ã¯ãã»ãªã³ïŒcycloserine; JANïŒãŸãã¯ã·ã¯ãã»ãªã³ã¯ãçµæ žã®æ²»çã«çšããããæçç©è³ªã§ãããå
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Kynurenic acid (KYNA or KYN) is a product of the normal metabolism of amino acid L-tryptophan. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiological and neuropathological processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders. Conversely, increased levels of kynurenic acid have also been linked to certain pathological conditions.
Kynurenic acid was discovered in 1853 by the German chemist Justus von Liebig in dog urine, which it was apparently named after.
It is formed from L-kynurenine in a reaction catalyzed by the enzyme kynurenineâoxoglutarate transaminase. | äºãã«ã«é
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Thymine is a pyrimidine nucleobase that is uracil in which the hydrogen at position 5 is replaced by a methyl group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a pyrimidine nucleobase and a pyrimidone. | ç¡é
žããªãŠã ïŒãããããããªãŠã ãBarium nitrateïŒã¯ååŠåŒBa(NO3)2ã§è¡šãããããªãŠã ã®ç¡é
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Phenolphthalein is a member of phenols. It is functionally related to a 2-benzofuran-1(3H)-one. | ã¢ã»ããããµããïŒAcetohexamideïŒã¯ãã¹ã«ããã«ãŠã¬ã¢ç³»çµå£è¡ç³éäžè¬ã®äžçš®ãæ¥æ¬ã§ã¯ãžã¡ãªã³ã®è²©å£²åã§æµéããŠããã | 0 |
Naringenin is a natural product found in Camellia sinensis, Humulus lupulus, and other organisms with data available. | ããªã³ã²ãã³ïŒNaringeninïŒã¯ãååŠåŒC15H12O5ã§è¡šããããã©ããã³ã®1çš®ã§ãããããªã«ãã³ãããªã³ã®ã³ããã«ãã³ã®ã¢ã°ãªã³ã³ãšããŠç¥ãããã | 1 |
Itraconazole is an N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. It has a role as a P450 inhibitor, an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor and a Hedgehog signaling pathway inhibitor. It is a member of triazoles, a dioxolane, a N-arylpiperazine, a dichlorobenzene, a cyclic ketal, a conazole antifungal drug, a triazole antifungal drug and an aromatic ether. | ãšã»ããªã³(Eseroline)ã¯ããªããªã€ãã¢ãŽãã¹ããšããŠäœçšããè¬å€ã§ãããã¢ã»ãã«ã³ãªã³ãšã¹ãã©ãŒãŒé»å®³å€ãã£ãŸã¹ãã°ãã³ã®ä»£è¬ç©è³ªã§ãããããã£ãŸã¹ãã°ãã³ãšã¯ç°ãªããã¢ã»ãã«ã³ãªã³ãšã¹ãã©ãŒãŒé»å®³äœçšã¯åŒ±ãã容æã«éè¡ããÎŒ-ãªããªã€ãå容äœã«åªä»ãããããªã匷ãé®çå€å¹æã瀺ãããã®æ··ååã®æŽ»æ§ã®ããããšã»ããªã³ã®è¬çäœçšã®ãããã¡ã€ã«ã¯ããªãç¬ç¹ãªãã®ãšãªãããäœææ°é害ãç¥çµæ¯æ§çã®å¯äœçšã®ãããå©çšã¯éãããŠããã | 0 |
Chelidonine is an isolate of Papaveraceae with acetylcholinesterase and butyrylcholinesterase inhibitory activity. | ãã§ãã«ã¢ã»ãã³ïŒè±: PhenylacetoneïŒã¯ãã¢ã»ãã³ã®Î±æ°ŽçŽ ã®1ã€ããã§ãã«åºã§çœ®æãããææ©ååç©ã®äžçš®ã§ããããã§ãã«-2-ããããã³ã®ç¥ç§°ããP2Pãšãè¡šèšãããã | 0 |
Cyclobutane is a cycloalkane and a member of cyclobutanes. | ãšã¹ããªãªãŒã«ïŒè±: Estriol, E3ïŒã¯ããšã¹ããã²ã³ã®äžçš®ãæ¯äœã®èèãšèç€ãèå
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Paraldehyde is a trioxane that is 1,3,5-trioxane substituted by methyl groups at positions 2, 4 and 6. It has a role as a sedative. | 5-ããããã·ã€ãœå°¿é
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Metronidazole is a natural product found in Euglena gracilis and Streptomyces hygroscopicus with data available. | ã¡ãããããŸãŒã«ïŒè±: metronidazoleïŒã¯ãããã€ãããŸãŒã«ç³»ã®æåè«è¬ãæèè¬ã®ã²ãšã€ãæ¥æ¬ã§ã¯åååãã©ãžãŒã«ãªã©ã§ç¥ãããã | 1 |
Gyrophoric acid is a tridepside that can be found in the lichen Cryptothecia rubrocincta and in Xanthoparmelia pokomyi. It is a double ester of the orsellinic acid. It can also be found in most of the species of the Actinogyra, Lasallia, and Umbilicaria genera. | æ°ŽïŒã¿ããïŒè±: waterãä»èšèªåŒç§°ã¯ãä»èšèªã§ã®åŒç§°ãã®é
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Sulforaphane is an isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen. It has a role as an antineoplastic agent, a plant metabolite, an antioxidant and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a sulfoxide and an isothiocyanate. | äºé
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Narasin is a coccidiostat and antibacterial agent. It is a derivative of salinomycin with an additional methyl group. Narasin is produced by fermentation of a strain of Streptomyces aureofaciens. | ãžããããã·ã¢ã»ãã³ (dihydroxyacetone, DHA) ã¯ççŽ æ°3ã®ã±ããŒã¹ã§ãã°ãªã»ã«ã¢ã«ããããšäžŠã³æãå°ããªåç³ã§ãããç®èã«å¡åžãããšå°éºŠè²ãåããããããµã³ã¬ã¹ã¿ã³ãã³ã°çšã®èè²çè²æãšããŠäœ¿ãããŠããããµããŠãã€ã³ã³ããµããŠãããã粟補ããããã°ãªã»ãªã³ãé
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Hexyl acetate is the acetate ester of hexan-1-ol. It has a role as a metabolite. It is functionally related to a hexan-1-ol. | ã¯ãã«ãã³ã³ïŒè±: ChlordeconeïŒã¯ãææ©å¡©çŽ ååç©ã®äžçš®ã§ã蟲è¬ïŒæ®ºè«å€ïŒãšããŠè£œé ã»äœ¿çšãããã»ãããã€ã¬ãã¯ã¹ã®å解çæç©ãšããŠãçºçãããåååã®ã±ãã³ïŒKeponeïŒã§ãåŒã°ãããåœéçã«è£œé ã䜿çšãæ¢ã«çŠæ¢ãããŠããããå¥åº·è¢«å®³ãç°å¢æ±æã®åé¡ã¯21äžçŽãæ®ã£ãŠããã | 0 |
Medroxyprogesterone acetate is an acetate ester resulting from the formal condensation of the 17alpha-hydroxy group of medroxyprogesterone with the carboxy group of acetic acid. A widely used progestin in menopausal hormone therapy and in progestogen-only birth control. It has a role as a progestin, an androgen, a female contraceptive drug, a synthetic oral contraceptive, an adjuvant, an inhibitor, an antioxidant and an antineoplastic agent. It is a steroid ester, an acetate ester, a 20-oxo steroid, a 3-oxo-Delta(4) steroid and a corticosteroid. It is functionally related to a medroxyprogesterone. | ãã«ã®ãªã³(Pargyline)ã¯ãéå¯éçã§éžæçãªã¢ãã¢ãã³é
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2-Ethylhexyl salicylate is a natural product found in Camellia sinensis, Homo sapiens, and Lonicera japonica with data available. | ããªããžã³ (pyrimidine) ã¯ãææ©ååç©ã®äžçš®ã§ããã³ãŒã³ã®1,3äœã®ççŽ ãçªçŽ ã§çœ®æããããã®ã§ãããåååŒ C4H4N2ãååé 80.09 ã®è€çŽ ç°åŒè³éŠæååç©ã®ã¢ãã³ã®äžçš®ã§ãç¹æã®åºæ¿èãæã€ãçªçŽ ååã®äœçœ®ãç°ãªãæ§é ç°æ§äœã«ãã©ãžã³ãšããªããžã³ãããã | 0 |
Cystamine is an organic disulfide obtgained by oxidative dimerisation of cysteamine. It has a role as an EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor. It is an organic disulfide and a primary amino compound. It is functionally related to a cysteamine. | ã·ã¹ã¿ãã³ (cystamine) ã¯ããžã¹ã«ãã£ãçµåãæããææ©ååç©ã®äžã€ãã·ã¹ãã³ãè±çé
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Nitrocyclohexane is a C-nitro compound that is cyclohexane in which a single hydrogen is replaced by a nitro group. It is a carbocyclic compound and a nitrohydrocarbon. | ã¯ãããã³ãŒã³ïŒè±: chlorobenzeneïŒã¯ãææ©ååç©ã®äžçš®ã§ãåååŒ C6H5Cl ãšè¡šãããããã²ã³åã¢ãªãŒã«ïŒè³éŠæããã²ã³åç©ïŒãç¡è²ã§ãå¯çæ§ã®æ¶²äœããµã€ãã¯äžçœ®æäœã§ããã¢ãã¯ãããã³ãŒã³ã®ããšãæããæ¶é²æ³ã«å®ãã第4é¡å±éºç© 第2ç³æ²¹é¡ã«è©²åœããã | 0 |
Adipamide is a fatty amide. | ãã§ãã«é
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Pentaerythritol tetranitrate is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to those of glyceryl trinitrate, but with a more prolonged duration of action, and is used for treatment of angina pectoris. It is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex. It has a role as an explosive and a vasodilator agent. | éé
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Prephenic acid is a natural product found in Neurospora crassa with data available. | ãã¬ãã§ã³é
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Phenacetin is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group. It has a role as a non-narcotic analgesic, a peripheral nervous system drug and a cyclooxygenase 3 inhibitor. It is a member of acetamides and an aromatic ether. It is functionally related to a N-phenylacetamide, a 4-ethoxyaniline and a paracetamol. | ãã«ã¡ã¿ãããªã³(Normetanephrine)ã¯ããã«ã¢ãã¬ããªã³ã«ã«ãã³ãŒã«-O-ã¡ãã«ãã©ã³ã¹ãã§ã©ãŒãŒãäœçšããŠçæããããã«ã¢ãã¬ããªã³ã®ä»£è¬ç©è³ªã§ãããå°¿äžã«æåºããããŸãç¹å®ã®çµç¹äžã«èŠããããè€è²çŽ°èè
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Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. In the very rare case of congenital adrenal hyperplasia due to 17α-hydroxylase deficiency cortisol production is blocked. | ããµã¹ããžã³(Desaspidin)ã¯ãé§è«è¬ã§ããããªã·ãå±ã®Dryopteris argutaäžã«å€©ç¶ã«å«ãŸããã1950幎代ãããèç·äœå
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Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessiveâcompulsive disorder (OCD), anxiety, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. It is also approved for treatment of major depressive disorder in adolescents and children 8 years of age and over. It has also been used to treat premature ejaculation. Fluoxetine is taken by mouth.
Common side effects include loss of appetite, nausea, diarrhea, headache, trouble sleeping, dry mouth, and sexual dysfunction. Serious side effects include serotonin syndrome, mania, seizures, an increased risk of suicidal behavior in people under 25 years old, and an increased risk of bleeding. Antidepressant discontinuation syndrome is less likely to occur with fluoxetine than with other antidepressants, but it still happens in many cases. Fluoxetine taken during pregnancy is associated with significant increase in congenital heart defects in the newborns. It has been suggested that fluoxetine therapy may be continued during breastfeeding if it was used during pregnancy or if other antidepressants were ineffective.
Fluoxetine was invented by Eli Lilly and Company in 1972, and entered medical use in 1986. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2022, it was the 22nd most commonly prescribed medication in the United States, with more than 24 million prescriptions.
Eli Lilly also markets fluoxetine in a fixed-dose combination with olanzapine as olanzapine/fluoxetine (Symbyax), which was approved by the U.S. FDA for the treatment of depressive episodes of bipolar I disorder in 2003 and for treatment-resistant depression in 2009. | ç¡«é
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Carvacrol is a phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1). It has a role as a volatile oil component, a flavouring agent, an antimicrobial agent, an agrochemical and a TRPA1 channel agonist. It is a member of phenols, a p-menthane monoterpenoid and a botanical anti-fungal agent. It derives from a hydride of a p-cymene. | ãã³ããªã¢ã³ã³ã¿ã³ (è±: Hentriacontane) ãšã¯çåæ°ŽçŽ ã®äžçš®ã§ãççŽ ã31é£ãªã£ãçŽéã¢ã«ã«ã³ãåååŒã¯ C31H64ããªããæ§é ç°æ§äœã®çš®é¡ã¯10,660,307,791çš®ãš100åãè¶
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Molindone is a member of indoles. | ãªã¹ã©ãžã³ (osladine) ã¯ã倩ç¶ã«ååšãã匷ãçã¿ããã€çå³æã§ãã·ãé¡ã®ãªãªãšãŸãã³ã Polypodium vulgare ïŒãŠã©ãã·ç§ïŒã®å°äžèããåé¢ããããåœæã®ãã§ã³ã¹ãããã¢ã§1967幎ã«çºèŠããããªãªãšãŸãã³ãã®ãã§ã³èªã§ã®å称"osladic"ã«ã¡ãªã¿åœåããããå¹³é¢ååŠæ§é ã¯1971幎ãç«äœååŠã¯ãœã©ãœãžã³ããã®éšååæãå
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Sulfadoxine is a sulfonamide consisting of pyrimidine having methoxy substituents at the 5- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. In combination with the antiprotozoal pyrimethamine (CHEBI:8673) it is used as an antimalarial. It has a role as an antibacterial drug and an antimalarial. It is a sulfonamide and a member of pyrimidines. | ãªãã³ãŒã«é
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Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. In addition, pregnenolone is biologically active in its own right, acting as a neurosteroid.
In addition to its role as a natural hormone, pregnenolone has been used as a medication and supplement; for information on pregnenolone as a medication or supplement, see the pregnenolone (medication) article. | ãã¬ã°ãããã³ (pregnenolone) ã¯ãããã²ã¹ããã³ãã³ã«ãã³ã€ããã¢ã³ããã²ã³ãããã³ãšã¹ããã²ã³ã®ã¹ããã€ãçæã«ãããããããã«ã¢ã³ã§ããããã¬ã°ãããã³ã¯äœå
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Terazosin, sold under the brand name Hytrin among others, is a medication used to treat symptoms of an enlarged prostate and high blood pressure. For high blood pressure, it is a less preferred option. It is taken by mouth.
Common side effects include dizziness, headache, feeling tired, swelling, nausea, and low blood pressure with standing. Severe side effects may include priapism and low blood pressure. Prostate cancer should be ruled out before starting treatment. It is an alpha-1 blocker and works by relaxing blood vessels and the opening of the bladder.
Terazosin was patented in 1975 and came into medical use in 1985. It is available as a generic medication. In 2021, it was the 234th most commonly prescribed medication in the United States, with more than 1 million prescriptions. | ããããã·ã«ïŒäžè¬åãè±èª: nitroxylïŒãŸãã¯ãã¢ã¶ãã³ïŒIUPACåãè±èª: azanoneïŒã¯ãååŠåŒã HNO ã®ååç©ã§ãããæ°çžã§ã¯ããç¥ãããŠãããããããã·ã«ã¯ã溶液çžã§ç寿åœã®äžéäœãšããŠåœ¢æããããHNOãšNO-ã¯é
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Propyl acetate, also known as propyl ethanoate, is an organic compound. Nearly 20,000 tons are produced annually for use as a solvent. This colorless liquid is known by its characteristic odor of pears. Due to this fact, it is commonly used in fragrances and as a flavor additive. It is formed by the esterification of acetic acid and propan-1-ol, often via FischerâSpeier esterification, with sulfuric acid as a catalyst and water produced as a byproduct. | é
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žãããã«ïŒãããããããã«ãpropyl acetateïŒãããã¯ãšã¿ã³é
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Estragole is a phenylpropanoid that is chavicol in which the hydroxy group is replaced by a methoxy group. It has a role as a flavouring agent, an insect attractant, a plant metabolite, a genotoxin and a carcinogenic agent. It is an alkenylbenzene, a monomethoxybenzene and a phenylpropanoid. It is functionally related to a chavicol. | ã°ãªã·ã³ã¢ããïŒè±èª: glycinamideïŒã¯ãååŠåŒã H2NCH2C(O)NH2 ã®ææ©ååç©ã§ãããã¢ããé
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ã°ãªã·ã³ã¢ããã¯ãã°ãªã·ã³ã¢ãããªããã¯ã¬ãªããïŒde novoããªã³çåæã«ãããäžéäœïŒã®åæã«äœ¿ãããè©Šè¬ã§ããã | 0 |
Digitoxin is a natural product found in Digitalis viridiflora, Digitalis grandiflora, and other organisms with data available. | ã¯ããªã³é
ž(Coumalic acid)ã¯ãååŠåŒC6H4O4ã®ææ©ååç©ã§ãããèç¹ã¯ãçŽ210âã§ããã | 0 |
Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity.
A derivative is used in Trastuzumab deruxtecan. | ã¢ã¶ããã³ïŒè±:azaperoneïŒãšã¯ç¥çµé®æè¬ã®1ã€ãããããã§ãã³èªå°äœã®1ã€ãåé èã蟺çžç³»ãç·æ¡äœãèŠåºäžéšãªã©ã®ããŒããã³å容äœã«äœçšããŠã粟ç¥å®å®äœçšãçºæ®ãããçµ±å倱調çããã€ç
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Naphthalene is an organic compound with formula C10H8. It is the simplest polycyclic aromatic hydrocarbon, and is a white crystalline solid with a characteristic odor that is detectable at concentrations as low as 0.08 ppm by mass. As an aromatic hydrocarbon, naphthalene's structure consists of a fused pair of benzene rings. It is the main ingredient of traditional mothballs. | èé
žïŒãããããchrysanthemic acidïŒã¯ãæ§ã
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žã®4çš®ã®ç«äœç°æ§äœã®äžã€ã§ãã (1R,3R)- or (+)-trans-chrysanthemic acidã¯ãé€è«è (Chrysanthemum cinerariaefolium) ã®çš®åã«å«ãŸãããã¬ããªã³Iã®é
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Risperidone is a member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2. It has a role as a serotonergic antagonist, an alpha-adrenergic antagonist, a H1-receptor antagonist, a second generation antipsychotic, a dopaminergic antagonist, a psychotropic drug and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is a pyridopyrimidine, an organofluorine compound, a heteroarylpiperidine and a member of 1,2-benzoxazoles. | ãã©ãžã³ïŒè±: PyrazineïŒã¯åååŒC4H4N2ã®è€çŽ ç°åŒååç©ã§ãããè³éŠæååç©ã®äžã€ããã³ãŒã³ã®1,4äœã®ççŽ ãçªçŽ ã§çœ®æããã察称çãªæ§é (ç¹çŸ€D2h)ãæã€ã
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Salicylaldehyde is a hydroxybenzaldehyde carrying a hydroxy substituent at position 2. It has a role as a nematicide and a plant metabolite. | ãããã«ã€ã³ã¯ãã¢ããåã®å±æ麻é
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Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. It is an alternative treatment for Pneumocystis pneumonia together with clindamycin. It is taken by mouth.
Common side effects include nausea, vomiting, and stomach cramps. Primaquine should not be given to people with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to the risk of red blood cell breakdown. It is often recommended that primaquine not be used during pregnancy. It may be used while breastfeeding if the baby is known not to have G6PD deficiency. The mechanisms of action is not entirely clear but is believed to involve effects on the malaria parasites' DNA.
Primaquine was first made in 1946. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. | ããªãžã³(Viridin)ã¯ãGliocladium virensã®æèæ§ä»£è¬ç©ã§ã1945幎ã«åããŠå ±åãããããã©ãã¹ããã€ãã®1ã€ã§ãæ±é»åã®ãã©ã³ç°ãC-4äœãšC-6äœã®éã§ã¹ããã€ãéªšæ Œã«èåããæ§é ãæã€ããŠã©ã«ãããã³ãå«ãããªãžã³é¡ã¯ãPI3ãããŒãŒã®äžå¯éçå
±æçµåé»å®³å€ã«ãªãããããšãç¥ãããŠããã | 0 |
Orotic acid () is a pyrimidinedione and a carboxylic acid. Historically, it was believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin.
The compound is synthesized in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase or a cytoplasmic enzyme of pyrimidine synthesis pathway. It is sometimes used as a mineral carrier in some dietary supplements (to increase their bioavailability), most commonly for lithium orotate. | ãã¢ã·ã³ (mimosine) ã¯ãã¢ã«ã«ãã€ããç°åžžã¢ããé
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Tautomycin is a carboxylic ester. | ãšã«ãŽã¿ãã³ïŒergotamineïŒã¯ããšã«ãŽãããã³ã®äžçš®ã§ãããã¢ã«ã«ãã€ãã®éºŠè§ãã¡ããªãŒã«å±ãããæ§é çãªãã³ã«çç©ååŠçã«ãšã«ãŽãªã³ãšè¿çžé¢ä¿ã«ãããããã€ãã®ç¥çµäŒéç©è³ªãšæ§é çé¡äŒŒæ§ããããè¡ç®¡åçž®è¬ãšããŠã®çç掻æ§ãæããã
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麻è¬åã³å粟ç¥è¬åç· æ³ã«ãã麻è¬å粟ç¥è¬åæã«æå®ãããŠããã | 0 |
Chlorophacinone is a diarylmethane and a beta-triketone. | ã€ã³ããªãžã³ïŒè±: indolizineïŒã¯è€çŽ ç°åŒè³éŠæææ©ååç©ã®äžçš®ã§ãããã€ã³ããŒã«ã®ç°æ§äœã«ãããã | 0 |
Proline is a natural product found in Angelica gigas, Microchloropsis, and other organisms with data available. | ãã³ãã³ã¢ããã¢ããã¯ã¬ãªããïŒnicotinamide mononucleotideãç¥ç§°:NMNãβ-NMNïŒã¯ããªããŒã¹ãšãã³ãã³ã¢ããã«ç±æ¥ãããã¯ã¬ãªããã§ãããNMNã¯ããã®äœå
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ããå¥åº·å¯¿åœã延ã°ãå¯èœæ§ã®ããç©è³ªãšããŠç 究ãããŠããã | 0 |
Prednisolone is a corticosteroid, a steroid hormone used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. It can be taken by mouth, injected into a vein, used topically as a skin cream, or as eye drops. It differs from the similarly named prednisone in having a hydroxyl at the 11th carbon instead of a ketone.
Common side effects with short-term use include nausea, difficulty concentrating, insomnia, increased appetite, and fatigue. More severe side effects include psychiatric problems, which may occur in about 5% of people. Common side effects with long-term use include bone loss, weakness, yeast infections, and easy bruising. While short-term use in the later part of pregnancy is safe, long-term use or use in early pregnancy is occasionally associated with harm to the baby. It is a glucocorticoid made from hydrocortisone (cortisol).
Prednisolone was discovered and approved for medical use in 1955. It is on the World Health Organization's List of Essential Medicines. It is available as a generic drug. In 2022, it was the 136th most commonly prescribed medication in the United States, with more than 4 million prescriptions. | ã¯ãªã»ã³ (chrysene) ãšã¯ãå€ç°è³éŠæçåæ°ŽçŽ (PAH) ã®äžçš®ã§ãåååŒã C18H12ã4åã®ãã³ãŒã³ç°ã蟺ãå
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Phthalic acid is a natural product found in Papaver somniferum, Cocos nucifera, and other organisms with data available. | é
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Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.
In 2021, it was the 272nd most commonly prescribed medication in the United States, with more than 900,000 prescriptions. | ã¡ãããããŒã«ïŒMetoprololïŒãšã¯ãã¢ãã¬ããªã³äœåæ§å¹æé®æè¬1ã€ã§ããã(RS)-1-ã€ãœãããã©ãã-3-{4-(2-ã¡ããã·ãšãã«)ãã§ããã·}ãããã³-2-ãªãŒã«ã®ããšã§ãããã€ãŸããã©ã»ãäœãšããŠäŸçµŠãããå»è¬åã§ãããã¡ãããããŒã«ã¯ã¢ãã¬ããªã³Î²1å容äœãéžæçã«é®æãããé«è¡å§ãäžæŽèã®æ²»çã«äœ¿çšãããã | 0 |
Hydroxycitronellal is a natural product found in Salvia sclarea with data available. | ããããã·ã·ãããã©ãŒã«ïŒè±: HydroxycitronellalïŒã¯ãååŠåŒC10H20O2ã§è¡šãããææ©ååç©ã§ãããã¹ãºã©ã³ã®éŠããæã¡ãéŠæ°Žãªã©ã«äœ¿ãããã | 1 |
Hydroxymethylbilane is a natural product found in Homo sapiens and Bos taurus with data available. | ã«ãã§ã€ã³ïŒè±èª: caffeineïŒã¯ãã¢ã«ã«ãã€ãã®1çš®ã§ãããããªã³ç°ãæã£ãããµã³ãã³ãšé¡äŒŒããæ§é ãæã£ãææ©ååç©ã®1ã€ãšããŠãç¥ãããããããªã©ã«å¯ŸããŠè奮äœçšãæã¡ãäžçã§æãåºã䜿ãããŠãã粟ç¥åºæ¿è¬ã§ãããã«ãã§ã€ã³ã¯ãã¢ããã·ã³å容äœã«æ®æããããšã«ãã£ãŠèŠéäœçšã解ç±é®çäœçšã匷å¿äœçšãå©å°¿äœçšã瀺ãã
å»è¬åã§ã¯ç·åæåè¬ãé®çè¬ãªã©ã«çšããããããã®éã®å¯äœçšãšããŠäžç ãããŸããªã©ãå«ãŸããããŸãã«ãã§ã€ã³ã®æžéãããã¯äžæ¢ã«ããçŠæçç¶ãšããŠãé çãéäžæ¬ åŠãç²åŽæãæ°åã®èœã¡èŸŒã¿ãªã©åãæ°ãçèçããããã2æ¥åŸãããŒã¯ãšããŠçããå Žåããããé çã¯1æ¥å¹³å235 mgã®æåã§ã2æ¥ç®ã«ã¯52%ãçµéšããã | 0 |
Sulfinpyrazone is a sulfoxide and a member of pyrazolidines. It has a role as a uricosuric drug. | ã«ããžã³(canadine)ã¯Corydalis cava(L.)ãå«æããããããã«ããªã³ ã¢ã«ã«ãã€ãã®äžã€ãã«ã«ã·ãŠã ãã£ãã«é»å®³äœçšãæã€ã | 0 |
Hydrastine is an isoquinoline alkaloid which was discovered in 1851 by Alfred P. Durand. Hydrolysis of hydrastine yields hydrastinine, which was patented by Bayer as a haemostatic drug during the 1910s. It is present in Hydrastis canadensis (thus the name) and other plants of the family Ranunculaceae. | ãã©ãŒãã ïŒè±: LorazepamïŒã¯ããã³ãŸãžã¢ãŒãã³ç³»ã®æäžå®è¬ã§ãããæç¶æéã¯äžçšåºŠã§ãæåºåæžæã¯çŽ12æéãæ¥æ¬ã§ã¯ãã¡ã€ã¶ãŒç€Ÿããã¯ã€ããã¯ã¹ (Wypax) ã®ã»ããåŸçºå»è¬åã販売ãããé©å¿ã¯ç¥çµçãå¿èº«çã«ãããäžå®ã»ç·åŒµã»æãã€ã§ããã | 0 |
Octocrylene is a diarylmethane. | ãããªãžã³ïŒè±èª: PiperidineïŒã¯ãææ©ååç©ã®1çš®ã§ã6å¡ç°æ§é ãæã€è€çŽ ç°åŒã¢ãã³ã§ãããè¡æ€ã®èŸå³æåãããªã³ã®æ§é äžã«ååšããè¡æ€ïŒPiperïŒã«ã¡ãªãã§åä»ããããããããµãããããªãžã³ããã³ã¿ã¡ãã¬ã³ã€ãã³ãšãåŒã°ããã | 0 |
Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life on Earth. Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP. Cyclic adenosine monophosphate (cAMP) is pervasive in signal transduction. Adenosine is used as an intravenous medication for some cardiac arrhythmias.
Adenosyl (abbreviated Ado or 5'-dAdo) is the chemical group formed by removal of the 5â²-hydroxy (OH) group. It is found in adenosylcobalamin (an active form of vitamin B12) and as a radical in the radical SAM enzymes. | ã°ã«ã¿ãã³ (glutamine) ã¯ã¢ããé
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Zanamivir is a medication used to treat and prevent influenza caused by influenza A and influenza B viruses. It is a neuraminidase inhibitor and was developed by the Australian biotech firm Biota Holdings. It was licensed to Glaxo in 1990 and approved in the US in 1999, only for use as a treatment for influenza. In 2006, it was approved for prevention of influenza A and B. Zanamivir was the first neuraminidase inhibitor commercially developed. It is marketed by GlaxoSmithKline under the trade name Relenza as a powder for oral inhalation. | 3-ã¡ãã«ãã©ã³ïŒè±èª: 3-methylfuranïŒã¯ãååŠåŒã C5H6O ã®ææ©ååç©ã§ãããããããã·ã«ã©ãžã«ã«ãšã€ãœãã¬ã³ãšã®æ°çžåå¿ã«ãã£ãŠçæããã | 0 |
Perillene is a monoterpenoid that is furan in which the hydrogen at position 3 is replaced by a 4-methylpent-3-en-1-yl group. A defensive allomone of thrips that has a flowery, citrus-like flavour. It has a role as a semiochemical, a metabolite and a fragrance. It is a member of furans and a monoterpenoid. | ãªãŒã©ã³ãããžã³ïŒAurantinidinïŒã¯ã氎溶æ§ã®èµ€è²ã®æ€ç©æ§ææã§ãããã¢ã³ãã·ã¢ãã³ãšããŠç¥ãããååç©çŸ€ã®äžã€ã§ããããã©ã«ãŽããžã³ã®ããããã·èªå°äœã§ããããªãŒã©ã³ãããžã³ã¯ãImpatients aurantiaca (Balsaminacea)ãã¢ã«ã¹ããã¡ãªã¢å±ã®æ œå¹åçš®ã«ãããŠçæãããšå ±åãããŠããã | 0 |
Butyl acetate is the acetate ester of butanol. It has a role as a metabolite. It is functionally related to a butan-1-ol. | ã·ã¯ãããã·ã«ã¢ãã³ïŒè±: CyclohexylamineïŒã¯ãèèªæã¢ãã³ã«å±ããææ©ååç©ã®äžçš®ã匷ãã¢ãã³èãæã€ç¡è²ã®æ¶²äœã§ãæ°Žãšæ··åãããä»ã®ã¢ãã³é¡ãšåæ§ãæ°Žé
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Cyclopentane is a natural product found in Oryza sativa and Senna sophera with data available. | ã«ãã§ããã³ (lufenuron) ãšã¯ãæè«æé·å¶åŸ¡å€ã®ã²ãšã€ãããã³è³ªã¯ç¯è¶³åç©ã®å€éªšæ Œã®æ§ææåã§ãããçºè²æã«åæããããã«ãã§ããã³ãªã©ã®ããã³è³ªåæé»å®³è¬ã¯ãããã³è³ªã®åæãé»å®³ããããšã«ããã幌è«ã®åµåããã³è±ç®ãé»å®³ããã
å ±åãããŠããèç¹ãLD50å€ã¯ãããã 174 âã>2000 mg/kgïŒã©ãããçµå£ïŒãCASç»é²çªå·ã¯[103055-07-8]ã | 0 |
Lansoprazole is a member of benzimidazoles, a member of pyridines and a sulfoxide. It has a role as an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor and an anti-ulcer drug. | ã¡ãã«ããã³é
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Marmesin (nodakenetin) is a chemical compound precursor in psoralen and linear furanocoumarins biosynthesis.
Marmesin plays a central role in the biosynthesis of furocoumarins in the plant ruta graveolens, more commonly known as rue. It acts as the natural intermediate in the formation of the furan ring that leads to a 4â,5â-dihydro furocoumarin-derivative. This substance can then be transformed into psoralen and other furocoumarins present in rue. Upon feeding the herb a dose of marmesin, radioactivity became strongly incorporated into psoralen and thus the plant itself. | ãã³ã€ã³ãµã³ (henicosane) ã¯ææ©ååç©ã§ãçŽéã¢ã«ã«ã³ã®äžçš®ãååŠåŒã¯ C21H44 ã®ãç¡è²ã®ããŠç¶åºäœããã€ãŠã¯ãã³ãšã€ã³ãµã³ (heneicosan) ãšåŒã°ããŠãããç°æ§äœã®æ°ã¯910726ã | 0 |
Galaxolide is an organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics. It has a role as a fragrance. It is a member of isochromenes and an organic heterotricyclic compound. | ã«ã«ããã³ïŒcarnitineïŒã¯ãçäœã«ãããŠè質ã®ä»£è¬ã«é¢äžãããã¿ãã³æ§ç©è³ªã§ãããã«ã«ããã³ã¯ããã®çäœå
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Hesperidin is a disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a mutagen. It is a disaccharide derivative, a member of 3'-hydroxyflavanones, a dihydroxyflavanone, a monomethoxyflavanone, a flavanone glycoside, a member of 4'-methoxyflavanones and a rutinoside. It is functionally related to a hesperetin. | ãã¡ã³ãããã¡ãŸã³(Famprofazone)ã¯ããã©ãŸãã³ç³»ã®éã¹ããã€ãæ§æççè¬ã§ãå°æ¹Ÿçããã€ãã®åœã§ã¯äžè¬çšå»è¬åãšããŠå
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Deserpidine is a natural product found in Aspergillus malignus, Rauvolfia serpentina, and other organisms with data available. | ãã»ã«ããžã³(Deserpidine)ã¯ãã€ã³ããžã£ãã¯å±ã«å«ãŸããã¬ã»ã«ãã³ã«äŒŒãé«è¡å§æ²»çè¬ã§ããã | 1 |
Perfluorobutanesulfonic acid is a perfluoroalkanesulfonic acid that is butane-1-sulfonic acid in which all of the hydrogens of the butyl group have been replaced by fluorines. It has a role as a surfactant. | 没é£åé
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Tetrathiafulvalene is a member of the class of fulvalenes that is ethene substituted by 1,3-dithiol-2-ylidene groups at positions 1 and 2. It is an organosulfur heterocyclic compound and a member of fulvalenes. | ãšãã«ãã«ããŒã«ïŒEthyl maltolïŒã¯éŠæãšããŠçšããããææ©ååç©ã§ããã«ããŒã«ã®ã¡ãã«åºããšãã«åºã«çœ®æããæ§é ãæã€ãIUPACåã¯2-ãšãã«-3-ããããã·-4-ãã©ãã³ïŒ2-Ethyl-3-hydroxy-4-pyranoneïŒã§ããã®ä»ã«2-Ethyl pyromeconic acidã2-ethyl-3-hydroxy-4-pyroneãšãåŒã°ãããCASçªå·ã¯[4940-11-8]ã | 0 |
Triazane is an inorganic compound with the chemical formula NH2NHNH2 or N3H5. Triazane is the third simplest acyclic azane after ammonia and hydrazine. It can be synthesized from hydrazine but is unstable and cannot be isolated in the free base form, only as salt forms such as triazanium sulfate. Attempts to convert triazanium salts to the free base release only diazene and ammonia. Triazane was first synthesized as a ligand of the silver complex ion: tris(ÎŒ2-triazane-κ2N1,N3)disilver(2+). Triazane has also been synthesized in electron-irradiated ammonia ices and detected as a stable gas-phase product after sublimation. | ãªãããªã³(Littorine)ã¯ããã§ãŠã»ã³ã¢ãµã¬ãªå±ããã©ãã³ãã«å«ãŸãããããã³ã¢ã«ã«ãã€ãã§ãããã¢ãããã³ãããšã¹ãã¢ãã³ãã¹ã³ãã©ãã³çãšååŠæ§é ãé¡äŒŒããŠããããããã¯å
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Isoprene is a hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds. It has a role as a plant metabolite. It is an alkadiene, a hemiterpene and a volatile organic compound. | ã¹ãããã§ã³(Suprofen)ã¯ãã€ã³ã»ã³ ãã¡ãŒããéçºããéã¹ããã€ãæ§æççè¬ (NSAIDs) ã§ãããé å€ãç®è¬ãšããŠã®ç±³åœã§ã®äœ¿çšã¯äžæ¢ãããŠãããæ¥æ¬ã§ã¯åçš®ã®æ¹¿ç¹ã«é©å¿ãæã€å€çšå€ã販売ãããŠãããåååã¯ã¹ã«ãããã³ãã¹ã¬ã³ãã ãããã«ãžãã¯ãå¯äœçšãšããŠå
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Calcium oxide (formula: CaO), commonly known as quicklime or burnt lime, is a widely used chemical compound. It is a white, caustic, alkaline, crystalline solid at room temperature. The broadly used term lime connotes calcium-containing inorganic compounds, in which carbonates, oxides, and hydroxides of calcium, silicon, magnesium, aluminium, and iron predominate. By contrast, quicklime specifically applies to the single compound calcium oxide. Calcium oxide that survives processing without reacting in building products, such as cement, is called free lime.
Quicklime is relatively inexpensive. Both it and the chemical derivative calcium hydroxide (of which quicklime is the base anhydride) are important commodity chemicals. | ã»ãã¡ãŸãªã³(Cefazolin, ãŸãã¯Cefazolilne, ãŸãã¯Cephazolin)ã¯ãå€ãã®çŽ°èææçã®æ²»çã«äœ¿çšãããæçç©è³ªã§ãããå
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Ferruginol is an abietane diterpenoid that is abieta-8,11,13-triene substituted by a hydroxy group at positions 12. It has a role as an antineoplastic agent, an antibacterial agent, a protective agent and a plant metabolite. It is an abietane diterpenoid, a member of phenols, a carbotricyclic compound and a meroterpenoid. | å¯äœçšã¯äžç ã錻ãžã®åºæ¿ãåãæ°ãé çããããããã é·æéã«ããã䜿çšã¯ã䜿çšãæ¢ãããšãã«è¬å€æ§è¥åæ§éŒ»ç ãåŒãèµ·ããå¯èœæ§ãããããå§ããããªããåŠåš äžã®äœ¿çšã¯å§ããããªãããã·ãã¡ã¿ãŸãªã³ã¯å
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Isoquinoline is an individual chemical specimen - a heterocyclic aromatic organic compound - as well as the name of a family of many thousands of natural plant alkaloids, any one of which might be referred to as "an isoquinoline". It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in many naturally occurring alkaloids such as papaverine. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine. | ããªã¯ããã¢ã»ããããªã« (Trichloroacetonitrile) ã¯ååŠåŒ CCl3CN ã§è¡šãããææ©ååç©ã§ãããæ¬æ¥ç¡è²ã ãåžè²©åã¯ãã°ãã°ãã£è²ã垯ã³ãŠãããå·¥æ¥çã«ã¯æ®ºèå€ãšããªãžã¢ãŸãŒã« (Etridiazole) ã®åé§äœãšããŠçšããããããã®ååç©ã¯ããªã¯ããã¢ã»ãã¢ããã®è±æ°Žã«ãã£ãŠè£œé ããããããªã¯ããã¢ã»ããããªã«ã¯äºå®èœåºååç©ãšããŠãããªã¯ããã¡ãã«åºãšãããªã«åºã®äž¡æ¹ã§åå¿ãå¯èœã§ãããããªã¯ããã¡ãã«åºã®é»ååžåŒæ§ããããªã«åºã®æ±æ žçä»å ã掻æ§åãããããªã¯ããã¢ã»ããããªã«ã«ã¯é«ãåå¿æ§ããããããã®ããå æ°Žå解ãããããã | 0 |
Jervine is a member of piperidines. | ããã«ã€ã³ã¢ããïŒè±: procainamideïŒã¯ãæäžæŽèè¬ã®ã²ãšã€ããŽã©ãŒã³ã»ãŠã£ãªã¢ã ãºåé¡ã§ã¯Ia矀ã«åé¡ããããCASç»é²çªå·ã¯ [51-06-9]ãå¿èã®åºæ¿äŒå°ç³»ã®ç°åžžãªé»æ°ã®æµããããããããšã«ããäžæŽãªãªãºã ãæ£åžžã«æ»ããåååã¯ãã¢ããµãªã³ã | 0 |
Fluconazole is a member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. It has a role as a P450 inhibitor, an environmental contaminant and a xenobiotic. It is a difluorobenzene, a conazole antifungal drug, a triazole antifungal drug and a tertiary alcohol. It is functionally related to a 1,3-difluorobenzene. It derives from a hydride of a 1H-1,2,4-triazole. | ãšãã«ãã³ãŒã³ (Ethylbenzene) ã¯ãçåæ°ŽçŽ ããã§ãã«ãšã¿ã³ (phenylethane)ããšãã«ãã³ãŸãŒã« (ethylbenzol) ãšãåŒã°ããããã³ãŒã³ç°äžã®1ã€ã®æ°ŽçŽ ããšãã«åºã§çœ®æããæ§é ãæã€ãååé 106.16ãèç¹ â95 âãæ²žç¹ 136 âãåžžæž©ã§ã¯ç¡è²éæã®æ¶²äœã§ãæ°Žã«ã¯ã»ãšãã©ãšããªãã | 0 |
Rugulosin is a cyclic ketone and an organic polycyclic compound. | ã«ã°ãã·ã³ïŒRugulosinïŒã¯ãããã·ãªãŠã å±ã®çèãç£çããåååŒC30H22O10ã®ã¢ã³ãã©ããã€ãç³»ãã€ã³ããã·ã³ã§ãããã«ã°ãã·ã³ã¯èæ¯æ§ããããçºçæ§ãããã | 1 |
Trimethyl borate is the organoboron compound with the formula B(OCH3)3 and a metal alkoxide. It is a colourless liquid that burns with a green flame. It is an intermediate in the preparation of sodium borohydride and is a popular reagent in organic chemistry. It is a weak Lewis acid (AN = 23, Gutmann-Beckett method).
Borate esters are prepared by heating boric acid or related boron oxides with alcohols under conditions where water is removed by azeotropic distillation. | ã·ãããªã³ (synephrine) ãŸãã¯p-ã·ãããªã³ã¯ãæ°çš®ã®åæ€ç©ãçæããã¢ã«ã«ãã€ãã®äžã€ããã«ã³ç§ãŠã³ã·ã¥ãŠãã«ã³ããããã«ã³ããã€ãã€ããŽã·ã¥ãŠãªã©ã«ãã«ã³ç§æ€ç©ãåºåãšããçè¬ã«å«ãŸããã¢ã«ã«ãã€ãã§ãè¡ç®¡åçž®äœçšãè¡å§äžæäœçšãæ°ç®¡æ¯çåŒç·©äœçšãèªããããŠããã
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Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia and ventricular fibrillation. When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area. It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding.
If injected intravenously, it may cause cerebral effects such as confusion, changes in vision, numbness, tingling, and vomiting. It can cause low blood pressure and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage. It appears to be generally safe for use in pregnancy. A lower dose may be required in those with liver problems. It is generally safe to use in those allergic to tetracaine or benzocaine. Lidocaine is an antiarrhythmic medication of the class Ib type. This means it works by blocking sodium channels and thus decreasing the rate of contractions of the heart. When injected near nerves, the nerves cannot conduct signals to or from the brain.
Lidocaine was discovered in 1946 and went on sale in 1948. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2021, it was the 267th most commonly prescribed medication in the United States, with more than 1 million prescriptions. | ã¬ã©ã¯ããã³ãã³ïŒGalactomannanïŒã¯å€ç³é¡ã®äžçŸ€ã§ããã³ããŒã¹ãããªãçŽç·ç¶äž»éïŒÎ²-(1-4)-D-ãã³ããã©ããŒã¹ïŒã«ã¬ã©ã¯ããŒã¹ïŒÎ±-D-ã¬ã©ã¯ããã©ããŒã¹ïŒãα-(1-6)-çµåãããã®ããããäžéšã®æ€ç©ãšèé¡ã«å«ãŸããã | 0 |
Thiosulfuric acid is a natural product found in Homo sapiens and Bos taurus with data available. | ã¯ããã£ãã©ãŒãïŒClofibrateïŒã¯ãè¡äžé«ã³ã¬ã¹ãããŒã«ããã³é«ããªã°ãªã»ãªãå€ã®ã³ã³ãããŒã«ã«çšãããããã£ãã©ãŒãç³»è質äœäžå€ã§ããããªãã¿ã³ãã¯è³ªãªããŒãŒæŽ»æ§ãé«ããŠVLDLããLDLãžã®å€æãä¿é²ããVLDLãæžå°ãããããŸããHDLãå¢å ãããå¹æãããã
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Benzene is a six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. It has a role as a non-polar solvent, a carcinogenic agent and an environmental contaminant. It is an aromatic annulene, a volatile organic compound and a member of benzenes. | ãã©ãã¯ããžã³ïŒtrabectedinïŒã¯æè
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Loratadine is a benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders. It has a role as a geroprotector, a H1-receptor antagonist, an anti-allergic agent and a cholinergic antagonist. It is an ethyl ester, a N-acylpiperidine, a tertiary carboxamide, an organochlorine compound and a benzocycloheptapyridine. It is functionally related to a desloratadine. | ãã©ã¿ãžã³ïŒLoratadineïŒã¯ãæç¶æ§éžæãã¹ã¿ãã³H1å容äœæ®æè¬ã§ãã¢ã¬ã«ã®ãŒæ§éŒ»çãè麻ç¹ã»ç®è湿ç¹ã«çšãããããåååã¯ã¯ã©ãªãã³ãæåç¹èš±ãåããŠãããåŸçºå»è¬åãååšããããŸãæ¥æ¬ã§2017幎ããäžè¬çšå»è¬åãçºå£²ãèèã®CYP3A4ã2D6ã«ãã£ãŠä»£è¬ãã掻æ§æåãšãªããããã®ãã¹ãã©ã¿ãžã³ïŒãã¶ã¬ãã¯ã¹ïŒã«ã¯ä»£è¬ã®ç«¶åã¯ãªããç¶ããŠå»è¬åãšããŠæ¿èªãããã
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Tandospirone is a dicarboximide that is (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione which is substituted by a 4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl group at position 2. It is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM). It has a role as an antidepressant and an anxiolytic drug. It is a N-alkylpiperazine, a N-arylpiperazine, a member of pyrimidines, a bridged compound and a dicarboximide. It is a conjugate base of a tandospirone(1+). | ããªãšãã«ã¢ãã³(Triethylamine)ã¯ã第äžçŽã¢ãã³ã«å±ããææ©ååç©ã®äžçš®ãé æåããšã£ãŠTEAãšãåŒã°ããã | 0 |
Etofenprox is a pyrethroid derivative which is used as an insecticide. Mitsui Chemicals Agro Inc. is the main manufacturer of the chemical. It is also used as an ingredient in flea medication for cats and dogs. | ãšããã§ã³ãããã¯ã¹(è±: etofenprox)ã¯ããã¬ã¹ãã€ãèªå°äœã«åé¡ãããååŠç©è³ªã®äžã€ã蟲æ¥çšæ®ºè«å€ããã¬ãã³ããšããŠè²©å£²ãããŠããã | 1 |
Phenol red is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. It has a role as a two-colour indicator, an acid-base indicator and a diagnostic agent. It is a 2,1-benzoxathiole, a member of phenols, a sultone and an arenesulfonate ester. | ãã§ããŒã«ã¹ã«ãã³ãã¿ã¬ã€ã³ïŒè±èª: phenolsulfonphthalein, PSPïŒãšã¯è²çŽ ã®äžçš®ã§ã氎溶液ãäžæ§ã§ã¯é»è²ãã¢ã«ã«ãªæ§ã§ã¯èµ€è²ã«å€åããããšãããpHæ瀺è¬ãšããŠçšããããååç©ãå¥åãšããŠãã§ããŒã«ã¬ãã (phenol red) ãšãåŒã°ããèµ€è²ã®åºäœã | 1 |
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically a cyclopyrrolone, used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system, via modulating GABAA receptors similarly to the way benzodiazepine drugs do inducing sedation but not with the anti-anxiety properties of the benzodiazepines.
Zopiclone is a sedative. It works by causing a depression or tranquilization of the central nervous system. After prolonged use, the body can become accustomed to the effects of zopiclone. When the dose is then reduced or the drug is abruptly stopped, withdrawal symptoms may result. These can include a range of symptoms similar to those of benzodiazepine withdrawal. Although withdrawal symptoms from therapeutic doses of zopiclone and its isomers (i.e., eszopiclone) do not typically present with convulsions and are therefore not considered life-threatening, patients may experience such significant agitation or anxiety that they seek emergency medical attention.
In the United States, zopiclone is not commercially available, although its active stereoisomer, eszopiclone, is. Zopiclone is a controlled substance in the United States, Japan, Brazil, New Zealand and some European countries, and may be illegal to possess without a prescription.
Zopiclone is known colloquially as a "Z-drug". Other Z-drugs include zaleplon and zolpidem and were initially thought to be less addictive than benzodiazepines. However, this appraisal has shifted somewhat in the last few years as cases of addiction and habituation have been presented. Zopiclone is recommended to be taken at the lowest effective dose, with a duration of 2â3 weeks for short-term insomnia. Daily or continuous use of the drug is not usually advised, and caution must be taken when the compound is used in conjunction with benzodiazepines, sedatives or other drugs affecting the central nervous system. | ãã¿ãã³ãŒã«ïŒBethanecholïŒãšã¯ã³ãªã³ãšã¹ãã«é¡ã«å±ããã³ãªã³äœåè¬ã®äžã€ã§ãããã ã¹ã«ãªã³å容äœã«çµåããããšã«ããå¯äº€æç¥çµæ§äœçšã瀺ãããã³ãã³å容äœã«ã¯äœçšããªããæ¶å管ãèè±å¹³æ»çã«å¯Ÿããäœçšã¯åŒ·ããã埪ç°åšç³»ãžã®äœçšã¯åŒ±ããæå°¿ä¿é²è¬ãšããŠå©çšããããã¢ã»ãã«ã³ãªã³ãšã¯ç°ãªãããã¿ãã³ãŒã«ã¯ã³ãªã³ãšã¹ãã©ãŒãŒã§å æ°Žå解ãããªãã®ã§ãäœçšæç¶æéãé·ããåååããµã³ãªã³ã | 0 |
Dodecane (also known as dihexyl, bihexyl, adakane 12, or duodecane) is an oily liquid n-alkane hydrocarbon with the chemical formula C12H26 (which has 355 isomers).
It is used as a solvent, distillation chaser, and scintillator component. It is used as a diluent for tributyl phosphate (TBP) in nuclear reprocessing plants. | ã«ãžã³ããŒã«(Luzindole)ãŸãã¯N-ã¢ã»ãã«-2-ãã³ãžã«ããªãã¿ãã³(N-acetyl-2-benzyltryptamine)ã¯ãäœå
ã§ã®ã¡ã©ããã³ã®åœ¹å²ãç 究ããããã«çšããããååŠç©è³ªã§ãããã«ãžã³ããŒã«ã¯ãMT1ã«å¯ŸããMT2ãžã®ã¢ãã£ããã£ãçŽ11ãã25åã倧ããéžæçãªã¡ã©ããã³å容äœã®ã¢ã³ã¿ãŽãã¹ããšããŠäœçšãããåç©å®éšã§ã¯ãæãã€å¹æã瀺ããšãšãã«ãæŠæ¥ãªãºã ãä¹±ãåãã芳å¯ãããã | 0 |
Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously.
Common side effects include nausea, vomiting, headaches, and diarrhea. Severe allergic reactions are rare. Liver problems have been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by slowing down bacterial protein synthesis. Clarithromycin resistance is already a major challenge to healthcare systems and such resistance is spreading, leading to recommendations to test the susceptibility of pathogenic organisms to the antibiotic before commencing clarithromycin therapy.
Clarithromycin was developed in 1980 and approved for medical use in 1990. It is on the World Health Organization's List of Essential Medicines. Clarithromycin is available as a generic medication. It is made from erythromycin and is chemically known as 6-O-methylerythromycin. | ãã©ã¹ããµã€ãžã³SïŒè±: Blasticidin SïŒã¯æçç©è³ªã®äžçš®ã§ãäž»ã«èŸ²æ¥çšæ®ºèå€ãšããŠäœ¿ãããã | 0 |
Cyclopentanone is a cyclic ketone that consists of cyclopentane bearing a single oxo substituent. It has a role as a Maillard reaction product. | ã¢ããšãã³é
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Folpet is the tradename for the organic compound with the formula C6H4(CO)2NSCCl3. It is a fungicide derived from phthalimide (C6H4(CO)2N-) and trichloromethylsulfenyl chloride. The compound is white although commercial samples can appear brownish. It is structurally related to Captan, which is also a trichloromethylsulfenyl-containing fungicide. | ããã¿ã³é
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