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On cessation of the injections, the retrocorneal membrane grew rapidly to involve the entire posterior cornea.
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Median patient age was 52 years.
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A whole brain irradiation was performed for 37.5Gy with a fraction size of 2.5Gy and gefitinib was replaced with erlotinib on the 5th day after radiation therapy commenced for disease progressing.
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Complex biochemical syndrome of hypocalcemia and hypoparathyroidism during cytotoxic treatment of an infant with leukemia.
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The fastidious organism grew only on buffered charcoal yeast extract agar and was confirmed as L. micdadei by gene sequence analysis.
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A patient who developed necrotizing pancreatitis after transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) is presented.
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RESULTS: Evidence of neurological improvement and rehabilitation potential after severe myelopathy due to intrathecal injection of doxorubicin.
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Diagnosis is often difficult and is typically only made in patients without another explanation for deteriorating renal function, and is often based solely on improvement after drug withdrawal.
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An associated finding included a 2+ positive antinuclear antibody test with a titer of 1:320.
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Patients in the intensive care unit seldom have mechanical small-bowel obstruction, and obstruction due to medication bezoars is even less common.
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CONCLUSION: This observation suggests that IFN in combination with ribavirin may offer an effective therapeutic option for liver transplant patients with severe recurrent hepatitis C.
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NCSE has not previously been reported in LBD.
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A less frequent side effect that is becoming more recognized is neurologic toxicity.
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The catheter had no blood return from either lumen for >1 month.
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Our cases constitute the most severe cases of benzarone hepatotoxicity reported so far, and comprise the first cases of (sub)fulminant hepatitis and cirrhosis related to benzarone.
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CONCLUSIONS: Cough has been encountered commonly after the administration of ACE inhibitors.
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We discuss the limitations of conventional drug therapy and the lack of a sustained response to plasmapheresis.
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There was also an improvement of the mesenteric arterial flow patterns on Doppler studies.
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Especially in small prostates, care should be taken to avoid this condition.
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We describe two patients who developed hypophosphatemia as a consequence of this form of therapy.
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A patient with disseminated herpes zoster developed a syndrome of inappropriate antidiuretic hormone and profound hyponatremia secondary to the administration of adenine arabinoside.
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Both patients had received brief courses of spironolactone before arginine treatment.
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Dermatologic exam demonstrated a severe reduction of fat tissue.
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Vitamin D toxicity complicating the treatment of senile, postmenopausal, and glucocorticoid-induced osteoporosis.
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Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment.
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A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.
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We report the case of a patient who developed polyserositis (pericardial effusion, pleural effusion, and pericarditis) after being started on clozapine, and whose symptoms remitted upon discontinuation of clozapine.
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Traditional risk factor analysis and screening were performed.
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We report a 13 year-old male who developed life-threatening anaphylaxis early in the course of Increlex therapy.
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A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy.
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At the age of 12, a prematurely born boy with an otherwise unremarkable past medical history developed bilateral optic neuritis associated with transverse myelopathy.
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The case of a young woman suffering from multiple autoimmune-dysreactive disorders (including thyreoiditis, myasthenia gravis, thymectomy, Crohn's disease, and erythema nodosum), while undergoing steroideal therapy, was complicated by a severe infectious disorder (severe upper urinary tract infection).
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Here, we present a case of sirolimus-associated interstitial pneumonitis in a cardiac transplant recipient that resolved completely with withdrawal of the drug and treatment with corticosteroids.
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Three patients achieved undetectable HIV loads with enfuvirtide salvage regimens.
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Extraskeletal tumoral calcifications (TC) may occur in patients with end-stage renal disease.
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Periosteal infusion of bupivacaine/morphine post sternal fracture: a new analgesic technique.
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We report a case culture-negative interface abscess following LASIK that was successfully treated with antibiotics and povidone iodine.
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Mycobacterium fortuitum bacteremia with granulomatous hepatitis complicating home cyclic parenteral nutrition through an indwelling Broviac catheter occurred in a 41-year-old woman.
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Radiotherapy enhances the toxicity of aminoglutethimide.
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Single case study.
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Ocular examination of both eyes revealed anterior subcapsular opacities of both lenses with the right eye being more severe than the left.
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To avoid hyperuricemia and an acute attack of gout after RFA therapy for HCC, early identification of patients at risk is warranted, such as those with a large tumor, rapid tumor growth, and renal insufficiency, and preventative measures should be considered.
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Therapy was continued for 8 months or longer in 6 patients, none of whom developed life-threatening infections.
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If cancer and AAA coincide and curative chemotherapy is possible, a potential impact of chemotherapy on AAA expansion should be considered.
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Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole.
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However, thereafter he suffered from serious infectious complications associated with immunosuppression and finally died 11 months after APOLT.
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It carries a well-known risk of neutropenia and agranulocytosis, which necessitates the immediate discontinuation of clozapine.
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CONCLUSIONS: There is very little published information regarding ofloxacin-induced toxic epidermal necrolysis.
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However, two children responded to the series of injections of hydrocortisone but not to single doses of methylprednisolone.
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Severe hepatotoxicity related to benzarone: a report of three cases with two fatalities.
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Excessive level of parathyroid hormone may induce the reduction of recombinant human erythropoietin effect on renal anemia.
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Torsade de pointes represents a potential complication of chronic amiodarone therapy.
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started having backache, fever and became operatively.
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Black cohosh is one of the most popular herbal therapies for premenstrual discomfort, hot flushes and other climacteric and menopausal symptoms.
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A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.
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We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.
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Healthcare providers and members of the public should be aware of the potential adverse effects of these remedies.
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Physicians should suspect pulmonary toxicity in patients with respiratory distress after gemcitabine chemotherapy, mainly in elderly patients.
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Risperidone-induced psychosis and depression in a child with a mitochondrial disorder.
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Toxic streptococcal syndrome is characterized by fever, shock, multiorgan system failure and a desquamating scarlatiniform rash.
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Furthermore, inadequate control of hypertension may have been another cause of hemorrhage.
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The patient developed infectious complications and died on hospital day 32.
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Quinine and its isomer quinidine are well-known causes of iatrogenic hypoglycaemia, due to excessive insulin secretion.
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Severe rhabdomyolysis developed within 5 hours after the injection.
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Therefore we recommend the less invasive approach first--urokinase therapy--to be followed by surgical intervention if thrombolysis is unsuccessful.
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An uncommon manifestation of phototoxicity, photo-onycholysis results in the separation of the distal nail from the nail bed.
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Amphotericin B (AmB) is effective, but its use is limited by toxicity: renal impairment, anaemia, fever, malaise, and hypokalaemia are common.
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Because of serious side effects of an increase in the QT interval causing torsades de pointes, dofetilide must be initiated with close monitoring of the QT interval in an inpatient setting.
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A 35-year-old woman was admitted to our hospital with the following complaints, headache, sweating, anxiety, dizziness, nausea, vomiting and severe hypertension.
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Three weeks later, diffusion abnormalities resolved, and T2-weighted studies showed increased signal intensity of prolonged T2 changes in areas of prior restricted diffusion.
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Antiphospholipid syndrome is an autoimmune disease that is characterised by tendency to thrombosis, obstetrical and hematological complications.
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Safety of nab-paclitaxel plus sunitinib: analysis of three cases.
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Reduction of methylprednisolone dosage rather than insulin therapy resulted in better control of glycemia.
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Symptoms resolved when systemic corticosteroids were administered.
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Neurologic symptoms resolved after stopping CAP for 4 weeks in Patient A, with no recurrence after reinitiating CAP alone at 2000 mg/m2.
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OBJECTIVE: To describe a series of patients with clinically significant lead poisoning.
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Coronary thrombolysis is contraindicated in patients with transient cerebral ischemia and stroke, arterial hypertension, cerebral trauma, cerebral aneurysms, and arteriovenous malformations, because of the risk of cerebral hemorrhage.
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He had received treatment with 400 mg of imatinib per day for 77 days, followed by dasatinib for 133 days.
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Antimonial derivatives induced a rapid remission.
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Treatment with sodium bicarbonate readily corrected a potentially life-threatening cardiac arrhythmia and is therefore suggested to be imperative in the treatment of these cases.
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Total scaphoidectomy and appropriate antibiotic therapy eradicated the infection.
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The patient was hospitalized and treated with a bolus as well as continuous infusion of intravenous magnesium sulfate.
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Despite significant improvement, extended plastic surgery was necessary for facial reconstruction.
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Two years later, his treatment was switched to olanzapine.
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Hyperosmolar hyperglycemic nonketotic coma.
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PURPOSE: The intravitreal application of triamcinolone acetonide as treatment of long-standing, therapy-resistant cystoid macular edema after penetrating keratoplasty is reported.
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We conclude that while thrombocytopenia and schistocytosis can be seen in quinine-associated TTP/HUS, the pathophysiology seems to be distinct from that seen in most cases of idiopathic TTP (i.e., severely decreased ADAMTS13 with an inhibitor).
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The clinical course as well as the biochemical pattern and the investigation of liver biopsy specimens enabled us to establish the diagnoses of drug-induced canalicular and hepatocanalicular cholestasis.
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Importantly, this was the first time that information became available about the effects of tamoxifen in healthy women, that is, women who did not already have breast cancer.
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A 42-year-old male underwent a total hip arthroplasty under subarachnoid anaesthesia with intrathecal bupivacaine and diamorphine.
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Surgery to remove the remaining tumor was performed 19 days later.
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Gastric mucosa hyperplasia is a rare cause of upper gastrointestinal obstruction in the neonatal period.
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A 69-year-old man with ulcerative colitis (UC) developed sensorimotor polyneuropathy.
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Subacromial impingement syndrome as a consequence of botulinum therapy to the upper trapezii: a case report.
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The patient's pain was well controlled with 10 mg continuous release morphine p.o. three times daily, and 10 mg immediate release morphine p.o. for breakthrough pain as required.
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He had been taking trimethoprim-sulfamethoxazole for approximately eight days when he revisited his family physician, complaining of headaches, dizziness, difficulty with speech, weakness, and itching on the trunk of his body and legs, where a maculopapular rash was noted.
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We report the first case of acute renal failure with hyperkalemia associated with the recently marketed direct renin inhibitor aliskiren.
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The possibility can be raised that M-CSF accelerated the underlying renal disease in this case through enhancing macrophage accumulation into the glomerulus, leading to the development of nephrotic syndrome.
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Thus, olanzapine dose reduction may permit treatment continuation where this is clinically indicated.
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Intravenous verapamil therapy in babies may cause apnea, hypotension, and bradycardia; continued episodes of atrial flutter in a child may cause sudden death; quinidine may be related to the death; children with "familial seizure disorders" may in fact have the long QT interval syndrome.
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ADE-Corpus-V2 Dataset: Adverse Drug Reaction Data.

This is a dataset for classification if a sentence is ADE-related (True) or not (False).

Train size: 17,637

Test size: 5,879

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