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The neurotoxicity was associated with oculomotor disturbances expressed primarily as weakness of convergence and divergence.
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This case describes the complications and successful treatment of high-dose intrathecal morphine overdose.
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The pupils were pinpoint.
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Hemostatic physiology involves a complex interlinking of blood and endothelial factors.
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We report a case of torsade de pointes following a single oral dose of amiodarone (1400 mg or 30 mg kg-1) administered after short intravenous loading for prevention of paroxysmal atrial flutter.
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Management of Graves' ophthalmopathy includes high-dose glucocorticoids.
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Bronchoscopic, cytologic, histopathologic, and virologic studies confirmed that necrotizing and exudative tracheobronchitis was due to herpes simplex virus.
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The blindness may have been a consequence of an immune reactivation inflammatory syndrome caused by this treatment.
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Hepatic hyperechogenicity on ultrasonography and slight elevation of serum transaminases might erroneously lead to a diagnosis of hepatic steatosis without liver histology.
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SETTING: Gimbel Eye Centre, Calgary, Alberta, Canada.
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After identification of the index patient, additional inquiry revealed that the patient's mother was hospitalized previously for overwhelming sepsis associated with metamizole use.
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Cultures of the anterior chamber were positive for Candida glabrata.
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Pharmacokinetically induced benzodiazepine withdrawal.
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The clinical manifestations of an anaphylactoid reaction are identical to true anaphylaxis; however, a previous exposure to the offending agent is not needed to manifest these symptoms.
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Early ICP was elevated, >50 mm Hg, and continuous EEG monitoring showed isoelectric readings.
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It is suggested that high dosage corticosteroids may damage the posterior blood-ocular barrier.
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Mexiletine hydrochloride was useful in preventing recurrences of torsades de pointes.
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It may or may not be accompanied by other features of toxicity.
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DATA EXTRACTION: Data from pertinent published sources were reviewed and abstracted.
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An acute ischaemic event associated with the use of venlafaxine: a case report and proposed pathophysiological mechanisms.
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CONCLUSIONS: In these 3 cases, the unique positive ocular finding was corneal endothelial deposits, which may be related to the use of rifabutin.
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All-trans-retinoic acid (ATRA) is considered the recommended induction treatment for acute promyelocytic leukemia (APL).
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While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect.
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The patient responded to aluminum chloride applied topically.
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In addition to the therapeutic benefits, prospective monitoring of free SDC in two of the patients also may have resulted in cost savings secondary to reduced hospital stay or less use of Fab.
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Antiretroviral-induced hepatic steatosis and lactic acidosis: case report and review of the literature.
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Although few reports of side effects have been published complications such as priapism and fibrosis of the spongy tissue are of concern.
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Progressive outer retinal necrosis presenting with isolated optic neuropathy.
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A 14-year-old girl with newly diagnosed SLE developed a pruritic bullous eruption while on prednisone.
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To our knowledge, neither the association of SINS and ankylosing spondylitis nor vertical diplopia as its presenting complaint has been described.
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These reports suggest the possibility that the risk of developing hyperglycemia and diabetic coma with this combination may be greater than when taking diuretics alone.
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At 8 years 8 months of age, desensitization was attempted because of refractoriness of seizures to drugs other than phenytoin.
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Rapid diagnosis may avert unnecessary changes in therapy to treat conditions which clinically mimic NEH.
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We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.
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It was possible to reproduce the disease by the intradermal injection of killed Group A streptococcal organisms.
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We administered SKT for a patient with thoracic outlet syndrome (TOS) complaining of several resting symptoms.
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Administration of excessive insulin induced hypoglycemia within 4 to 8 hours, followed by rebound hyperglycemia.
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Rapid formation of Aspergillus mycetoma in a patient receiving corticosteroid treatment.
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Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia, such as sulfonylureas, meglitinides, and insulin.
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Recent reports have shown that Decadron (dexamethasone; Merck Sharp & Dohme, West Point, Pa) has a significant antiemetic effect on cisplatin-induced vomiting.
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Dystonia is a common manifestation in Wilson's disease (WD).
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Iatrogenic vasculitis should be suspected when a patient with idiopathic vasculitis with one type of ANCA develops the other type of ANCA.
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Nodular scleritis following alendronate therapy.
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After 1 week of nefazodone therapy the patient experienced headache, confusion, and "gray areas" in her vision, without abnormal ophthalmologic findings.
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However, long-term PUVA therapy may cause several adverse effects including skin cancer, especially squamous cell carcinoma (SCC).
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Bilateral Acanthamoeba keratitis in Synergeyes contact lens wear: clinical and confocal microscopy findings.
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Atrial fibrillation after vardenafil therapy.
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Pentavalent antimonial drugs used for the treatment of leishmaniasis have been associated with sudden deaths, probably due to the development of ventricular tachyarrhythmias.
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Treatment with r-HuEPO does improve the quality of life and ability to work of uremic patients and does not adversely affect their transplant potential.
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BACKGROUND: Accutane a teratogenic prescription drug licensed to treat severe, recalcitrant nodular acne.
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A mechanism for the efficacy of this treatment is discussed.
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BACKGROUND: Bupropion, a novel antidepressant, has been reported to produce fewer adverse effects than the tricyclic antidepressants.
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The first patient showed a good response to olanzapine, but the RLS symptoms associated with olanzapine resulted in poor long-term compliance, eventually leading to frequent relapse of psychotic symptoms.
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The present report examines the case of a patient with longstanding Crohn's disease who had never been treated with corticosteroids and who developed osteonecrosis of the talus.
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Optometrists should be familiar with this condition, its signs, symptoms and correct treatment protocol.
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Specifically, after initiation of 500 mg MMF twice a day given in conjunction with the long-standing use of prednisone, which had been tapered to a dose of 10 mg daily, the patient's red blood cell count dropped by 17% over 7 weeks.
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However, 19 days after starting amiodarone, serum testing indicated a hypothyroid status that was not recognized clinically.
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There is growing evidence that various organic solvents give rise to a parkinsonism syndrome with pyramidal features in susceptible individuals.
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Systemic capillary leak syndrome after granulocyte colony-stimulating factor (G-CSF).
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We present a patient with multiple intraoral ulcerations of the right buccal and alveolar mucosa that had previously been treated with nerve ablation therapy for trigeminal neuralgia.
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To ensure safety and effectiveness, and to meet the requirements of accreditation agencies, hospitals should develop prescribing guidelines for IV opioid range orders and clear protocols for their implementation.
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Flurbiprofen-associated acute tubulointerstitial nephritis.
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The patient received only the ophthalmic sulfonamide, and it was used for one day, but he developed Stevens-Johnson syndrome.
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While the 2 patients without re-exposure to etanercept did not have further CD flares, the third patient flared 6 months after re-institution of etanercept in combination with azathioprine.
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In this brief report, we present case of successful cisplatin administration following two unsuccessful carboplatin desensitization attempts, and without the need for pre-treatment steroids.
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Initial measurements showed the patient was able to walk for one minute and 34 seconds on a treadmill (2 mph, 10% grade) before stopping because of claudication.
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After 4 months, the pain had almost entirely disappeared.
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A diffuse intrahepatic metastasis of a carcinoid was treated with a loco-regional intraarterial chemotherapy via a catheter system implanted in the gastroduodenal artery.
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This report describes a male college student who experienced akinesia lasting almost 3 weeks following withdrawal from relatively brief, low-dose neuroleptic treatment.
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Acute abdomen due to endometriosis in a premenopausal woman taking tamoxifen.
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OBJECTIVE: The objective of this study was to assess the efficacy of beta-blockade on clinically significant left ventricular outflow tract obstruction in premature infants treated with dexamethasone because of bronchopulmonary dysplasia.
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After mirtazapine therapy was discontinued, serum sodium concentrations normalized.
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Two patients with bipolar affective disorder and a history of bronchospastic phenomena experienced tremor during lithium carbonate therapy.
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Histopathology showed an increase in melanocyte numbers and melanogenesis.
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The authors also determined that their case of myositis developing in the rectus abdominus muscle of a patient with pancreatic adenocarcinoma was the manifestation of radiation recall, thereby bringing the number of patients who developed radiation recall to gemcitabine and were discussed in the current study to 13.
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We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.
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Since 1979, over 30 published case reports have documented the relationship between phenylpropanolamine and stroke.
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Testicular teratoma with a unique mode of spread and spontaneous maturation.
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A case report.
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BACKGROUND: A 56-year-old man with normal cardiac function received treatment with interferon alpha-2b for malignant melanoma.
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Patch testing to individual components revealed positive reactions to all ingredients except aloe.
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It is concluded that selective 5-HT4 agonists could be potentially useful to improve bladder emptying in micturition disorders associated with detrusor hypocontractility.
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Definitive diagnosis was obtained after a mean period of 4.5 weeks (range, 12 days-8 weeks) from onset.
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Central nervous system effects secondary to ciprofloxacin treatment are uncommon and usually consist only of minor dizziness or mild headache, although rare occurrences of seizures and hallucinations have been reported.
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A 55-yr-old man developed prolonged jaundice and sicca complex after a course of thiabendazole therapy.
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Mycobacterium bovis dissemination (BCG strain) among immunodeficient Brazilian infants.
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We describe a woman with relapsed cutaneous follicular centre B-cell lymphoma and secondary lymph-node involvement treated with rituximab alone, which induced a complete remission.
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Clonidine-induced bradycardia in patients with spinal cord injury.
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A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines.
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Environmental agents have long been thought to be linked to the development of malignancies.
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However, recently we were confronted with two cases within 1 month.
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CLINICAL FEATURES: A 34-yr-old man with long-standing insulin dependent diabetes mellitus underwent a total proctocolectomy for inflammatory bowel disease.
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In more than half of the cases there was evidence of prolonged elimination t1/2 or rebound of a serum concentration during the elimination phase corresponding to either an additional compartment or enterohepatic circulation of 6MP.
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Since this reaction was not present on the original aspiration cytology slides, the chemotherapy treatment must have induced this reaction.
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There have been conflicting reports as to whether clozapine, an atypical antipsychotic, will suppress symptoms of tardive dyskinesia.
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Drug induced acute parotitis is a very uncommon complication reported with a few drugs only.
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Severe tardive dystonia: treatment with continuous intrathecal baclofen administration.
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We conclude that, though rare, E. avium can be pathogenic in humans and that E. avium bacteremia is associated with gastrointestinal abnormalities.
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Two hours after a documented overdosage of more than 100 tablets oxcarbazepine, the serum level of the parent compound was 10-fold higher than the therapeutic dosage (31.6 mg l(-1)).
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In addition to PIA1 platelet antibodies, this patient had an associated anamnestic recall of multispecific red cell and lymphocytotoxic antibodies.
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