hcaoaf/MoleculeQA · Datasets at Hugging Face

text stringlengths 3 799
" B
2405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.
Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" B
60815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is widely used for therapy of mild-to-moderate pain and arthritis.
Option B: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.
Option C: It can be used for pain relief and adjunctive to an anaesthetic during surgery.
Option D: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.
" C
53232 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as first-line therapy in pain conditions.
Option B: It can be used as first-line options for the treatment of dyslipidemia.
Option C: It is commonly used as a first line therapy in the treatment of hypertension.
Option D: It is considered first-line options for the treatment of dyslipidemia.
" B
39186 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option B: It can be used to treat hypertension and angina pectoris.
Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias.
Option D: It can be used in the therapy of hypertension and angina pectoris.
" D
5215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.
Option B: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms.
Option C: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.
Option D: It is widely used for therapy of mild-to-moderate pain and arthritis.
" B
1615 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(CC1=CC2=C(C=C1)OCO2)NC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.
Option B: It can be used as a dissociative anesthetic drug with stimulant and hallucinogenic effects.
Option C: It can be used as a widely abused drug classified as a hallucinogen.
Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis.
" C
4485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option B: It can be used in the therapy of hypertension and angina pectoris.
Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias.
Option D: It can be used to treat hypertension and angina pectoris.
" D
5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is commonly used as a first line therapy in the treatment of hypertension.
Option B: It can be used for the treatment of autistic spectrum disorders.
Option C: It is used for the treatment of hypertension.
Option D: It is marketed for the treatment of hypertension.
" B
2662 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used predominantly to treat chronic arthritis.
Option B: It is widely used in the therapy of arthritis.
Option C: It is used in therapy of chronic arthritis.
Option D: It is used for the therapy of chronic arthritis.
" B
2997 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3
Question about this molecule: How can the molecule be used for treatment
Option A: It is used for treatment of gastrointestinal disorders.
Option B: It is used primarily in the treatment of anxiety.
Option C: It can be used for the treatment of major depression.
Option D: It can be used for the treatment of various diseases.
" B
20279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.
Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.
Option C: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.
" D
3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C(C(CS)S)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.
Option B: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery.
Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option D: It is used clinically for the treatment of poisoning by arsenic, mercury, gold, antimony, bismuth, and possibly thallium.
" D
3948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O
Question about this molecule: How can the molecule be used for treatment

" B

2405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.

Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" B

60815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is widely used for therapy of mild-to-moderate pain and arthritis.

Option B: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.

Option C: It can be used for pain relief and adjunctive to an anaesthetic during surgery.

Option D: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.

" C

53232 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as first-line therapy in pain conditions.

Option B: It can be used as first-line options for the treatment of dyslipidemia.

Option C: It is commonly used as a first line therapy in the treatment of hypertension.

Option D: It is considered first-line options for the treatment of dyslipidemia.

" B

39186 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option B: It can be used to treat hypertension and angina pectoris.

Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias.

Option D: It can be used in the therapy of hypertension and angina pectoris.

" D

5215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.

Option B: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms.

Option C: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.

Option D: It is widely used for therapy of mild-to-moderate pain and arthritis.

" B

1615 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(CC1=CC2=C(C=C1)OCO2)NC

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.

Option B: It can be used as a dissociative anesthetic drug with stimulant and hallucinogenic effects.

Option C: It can be used as a widely abused drug classified as a hallucinogen.

Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis.

" C

4485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option B: It can be used in the therapy of hypertension and angina pectoris.

Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias.

Option D: It can be used to treat hypertension and angina pectoris.

" D

5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is commonly used as a first line therapy in the treatment of hypertension.

Option B: It can be used for the treatment of autistic spectrum disorders.

Option C: It is used for the treatment of hypertension.

Option D: It is marketed for the treatment of hypertension.

" B

2662 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used predominantly to treat chronic arthritis.

Option B: It is widely used in the therapy of arthritis.

Option C: It is used in therapy of chronic arthritis.

Option D: It is used for the therapy of chronic arthritis.

" B

2997 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3

Question about this molecule: How can the molecule be used for treatment

Option A: It is used for treatment of gastrointestinal disorders.

Option B: It is used primarily in the treatment of anxiety.

Option C: It can be used for the treatment of major depression.

Option D: It can be used for the treatment of various diseases.

" B

20279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.

Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.

Option C: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.

Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.

" D

3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C(C(CS)S)O

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.

Option B: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery.

Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

Option D: It is used clinically for the treatment of poisoning by arsenic, mercury, gold, antimony, bismuth, and possibly thallium.

" D

3948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O

Question about this molecule: How can the molecule be used for treatment