hcaoaf/MoleculeQA · Datasets at Hugging Face

text stringlengths 3 799
" B
1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CN=CC=C1N
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used to help with mobility in these patients.
Option B: It is used for the treatment of migraine headaches.
Option C: It can be used for the treatment of migraine headaches.
Option D: It is used for treatment of gastrointestinal disorders.
" A
20299 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[N+](CC)(CC)CCC(C1CCCCC1)(C2=CC=CC=C2)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option B: It is used for its antibacterial, antifungal, and anthelmintic properties as a mixture of violet rosanilinis.
Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.
Option D: It can be used as an antimuscarinic, anticholinergic drug.
" D
702 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCO
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used as a drug with a depressive effect on the central nervous system.
Option B: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option D: It can be used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
" A
4781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the treatment of status epilepticus.
Option B: It should not be employed for the treatment of gouty arthritis.
Option C: It can be used for the treatment of treatment-resistant major depression.
Option D: It is highly effective for the management of the ""positive"" symptoms of schizophrenia.
" B
12620 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCO
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for topical treatment for recurrent herpes simplex labialis episodes.
Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.
Option D: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
" A
644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option C: It can be used for the treatment of Lennox-Gastaut syndrome and Dravet syndrome.
Option D: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
" C
3366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=NC(=O)NC(=C1F)N
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used as a Nucleoside Analog Antifungal.
Option B: It is used as a Benzylamine Antifungal.
Option C: It can be used as an Allylamine Antifungal.
Option D: It is used as an Echinocandin Antifungal.
" A
71158 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NCCCS(=O)(=O)O
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as a treatment for leishmaniasis.
Option B: It can be used in gynecology.
Option C: It is used in the treatment of giardiasis and cholera.
Option D: It can be used for the maintenance of alcohol abstinence.
" D
5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of treatment-resistant major depression.
Option B: It can be used for the treatment of severe long-term depression.
Option C: It can be used for the treatment of major depression.
Option D: It can be used for the treatment of various diseases.
" B
175805 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used as an aminoamide local anesthetic drug.
Option B: It is used as an antiseptic and antifungal agent.
Option C: It can be used as an antifungal antibiotic.
Option D: It can be used as an antibacterial and antifungal agent.
" A
14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O
Question about this molecule: How can the molecule be used for treatment
Option A: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.
Option C: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.
Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.
" C
2812 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option C: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
Option D: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery.
" C
2911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O
Question about this molecule: How can the molecule be used for treatment

" B

1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CN=CC=C1N

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used to help with mobility in these patients.

Option B: It is used for the treatment of migraine headaches.

Option C: It can be used for the treatment of migraine headaches.

Option D: It is used for treatment of gastrointestinal disorders.

" A

20299 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC[N+](CC)(CC)CCC(C1CCCCC1)(C2=CC=CC=C2)O

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

Option B: It is used for its antibacterial, antifungal, and anthelmintic properties as a mixture of violet rosanilinis.

Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.

Option D: It can be used as an antimuscarinic, anticholinergic drug.

" D

702 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCO

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used as a drug with a depressive effect on the central nervous system.

Option B: It can be used for the treatment of sickle cell disease, malaria, and some cancers.

Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

Option D: It can be used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

" A

4781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used in the treatment of status epilepticus.

Option B: It should not be employed for the treatment of gouty arthritis.

Option C: It can be used for the treatment of treatment-resistant major depression.

Option D: It is highly effective for the management of the ""positive"" symptoms of schizophrenia.

" B

12620 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCO

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used for topical treatment for recurrent herpes simplex labialis episodes.

Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.

Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.

Option D: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

" A

644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.

Option C: It can be used for the treatment of Lennox-Gastaut syndrome and Dravet syndrome.

Option D: It can be used for the treatment of sickle cell disease, malaria, and some cancers.

" C

3366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=NC(=O)NC(=C1F)N

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used as a Nucleoside Analog Antifungal.

Option B: It is used as a Benzylamine Antifungal.

Option C: It can be used as an Allylamine Antifungal.

Option D: It is used as an Echinocandin Antifungal.

" A

71158 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(=O)NCCCS(=O)(=O)O

Question about this molecule: How can the molecule be used for treatment

Option A: It is used as a treatment for leishmaniasis.

Option B: It can be used in gynecology.

Option C: It is used in the treatment of giardiasis and cholera.

Option D: It can be used for the maintenance of alcohol abstinence.

" D

5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used for the treatment of treatment-resistant major depression.

Option B: It can be used for the treatment of severe long-term depression.

Option C: It can be used for the treatment of major depression.

Option D: It can be used for the treatment of various diseases.

" B

175805 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used as an aminoamide local anesthetic drug.

Option B: It is used as an antiseptic and antifungal agent.

Option C: It can be used as an antifungal antibiotic.

Option D: It can be used as an antibacterial and antifungal agent.

" A

14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O

Question about this molecule: How can the molecule be used for treatment

Option A: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.

Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.

Option C: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains.

Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia.

" C

2812 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Question about this molecule: How can the molecule be used for treatment

Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.

Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.

Option C: It can be used for the treatment of sickle cell disease, malaria, and some cancers.

Option D: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery.

" C

2911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O

Question about this molecule: How can the molecule be used for treatment