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c1ea1c2926846d94f4574311942c701d648030ae | The Emotional Burden of Monotheism: Satan, Theodicy, and Relationship with God | The thesis of this research was that belief in Satan helps Christian believers attenuate ambivalent feelings about God in the face of painful life events. Two questions were examined. First, are robust notions of Satan associated with more positive feelings toward God? Second, are robust notions of Satan associated with blaming God less for the pain and suffering inherent in human existence? In study 1 robust notions of Satan did predict more positive experiences with God. In study 2 robust notions of Satan were manifested by participants who were less likely to blame God for the pain and suffering in the world. These trends were consistent with the experimental predictions suggesting that belief in Satan may be functioning as an attributional category to reduce theodic blame toward God. | [] | https://semanticscholar.org/paper/c1ea1c2926846d94f4574311942c701d648030ae | [] | [
{
"name": "Richard Beck",
"ids": [
"143801304"
]
},
{
"name": "Sara Taylor",
"ids": [
"144996285"
]
}
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] | [
"Psychology"
] | 2,008 | Journal of Psychology and Theology | 36 | 151 - 160 | [] | 10.1177/009164710803600301 | https://doi.org/10.1177/009164710803600301 | 2790166731 |
|||
1aa2b264f645b01a3d4f2b9a36e344f4d480387c | [Preventive therapy of opiate addiction with naltrexone]. | The trial included 120 patients with opiates addiction: the study group (60 patients) and a control one (60 individuals) which were similar in sex, age and clinical peculiarities of the disease. Naltrexon was administered prophylactically to the patients of the study group during 6 months and longer, while the patients of the control group didn't receive naltrexon. Simultaneously, a program of common therapy and rehabilitation concerning both groups was performed during 6 months. It was established that application of naltrexon decreased probability of relapse of drug abuse, facilitated an inclusion of a patient into a program of therapy and rehabilitation, increased a number and quality of remissions as well as it also decreased a tendency to alcohol and sedative drugs administration. Naltrexon had no side effects and was well tolerated by the patients. 8 follow-up cases of treatment with metadone in some foreign clinics are presented. These observations and literary data show that prophylactic properties of metadone are less pronounced as compared with naltrexon. | [] | https://semanticscholar.org/paper/1aa2b264f645b01a3d4f2b9a36e344f4d480387c | [] | [
{
"name": "Iu P Sivolap",
"ids": [
"3928709"
]
},
{
"name": "V A Savchenkov",
"ids": [
"5278089"
]
}
] | [
"d1b109a39bc0ea29921715149457147db7c57569"
] | [] | [
"Medicine"
] | 1,998 | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | 98 11 |
22-5
| [
"Medline"
] | 9845936 | 2410219447 |
|||
b3273978f7e2a73813dc66f4d83d00883a877c3e | Genetic Effects Analysis of Major Genes Underlying Plant Height and Main Stem Nodes in a Soybean Four-way Recombinant Inbred Lines Population through Maximum Likelihood Method | In order to predict the existence of major gene that control plant height and main stem nodes in a four-way recombinant inbred lines population(Kenfeng 14 × Kenfeng 15) ×(Heinong 48 × Kenfeng 19),three steps of constructing various model according to mating mode of multiple allels,estimating genetic effects by maximum likelihood method,selecting the best model,the genetic mode and genetic effects were analyzed.The result showed plant height was controlled by two major genes without interaction and inheridity mode,which were A1A2 × A3A4 and B1B2 × B1B3,respectively.The additive effects of the first major gene were-4.9,6.22,20.33 and that of the second major gene were-9.39,26.23,and the heredity of the major genes was 97%.Main stem nodes was controlled by one major gene and inheridity mode was A1A2 × A1A3.The additive effects of the major gene were 16.82,-1.32,2.64,and the heredity was 21%.The result indicated it was feasible to carry out QTL mapping on plant height and main stem nodes through four-way recombinant inbred lines population(Kenfeng 14 × Kenfeng 15) ×(Heinong 48 × Kenfeng 19). | [] | https://semanticscholar.org/paper/b3273978f7e2a73813dc66f4d83d00883a877c3e | [] | [
{
"name": "Wang De-liang",
"ids": [
"72731678"
]
}
] | [] | [] | [
"Biology"
] | 2,013 | Soybean Science | [] | 2394320900 |
|||||||
cb4db816cbfde720eaba5b43c70d7d85697caa1a | Biolabeling with nanoparticles based on Y2O3: Nd3+ and luminescence detection in the near-infrared | Abstract Neodymium based fluorescence presents several advantages in comparison to conventional rare earth or enzyme–substrate based fluorescence emitting sources (e.g.Tb, HRP) . Based on this fact we have herein explored a Nd-based fluoroimmunoassay. We efficiently detected the presence of an oxidized low-density lipoprotein (oxLDL) in human plasma a well-known marker for cardiovascular diseases, which causes around 30% of deaths worldwide. Conventional fluoroimmunoassay uses time-resolved luminescence techniques, with detection in the visible range, to eliminate the fluorescence background from the biological specimens. By using an immunoassay based on functionalized Y 2 O 3 :Nd 3+ nanoparticles, where the excitation and emission processes in the Nd 3+ ion occur in the near-infrared (NIR) region, we have succeeded in eliminating the interferences from the biological fluorescence background, avoiding the use of time-resolved techniques. This yields higher emission intensity from the Nd 3+ -nanolabels and efficient detection of anti-oxidized low-density lipoproteins (anti-oxLDL) by Y 2 O 3 :Nd 3+ -antibody–antigen conjugation, leading to a novel biolabeling method. | [] | https://semanticscholar.org/paper/cb4db816cbfde720eaba5b43c70d7d85697caa1a | [] | [
{
"name": "Cláudia A. Kodaira",
"ids": [
"11935427"
]
},
{
"name": "A. V. S Lourenço",
"ids": [
"40502647"
]
},
{
"name": "Maria C. F. C. Felinto",
"ids": [
"91006537"
]
},
{
"name": "Eduardo Milton Ramos Sanchez",
"ids": [
"48593380"
]
},
{
"name": "Francisco J. Rios",
"ids": [
"144139296"
]
},
{
"name": "Luiz Antônio de Oliveira Nunes",
"ids": [
"144876460"
]
},
{
"name": "Magnus Gidlund",
"ids": [
"47766520"
]
},
{
"name": "Oscar L. Malta",
"ids": [
"9866196"
]
},
{
"name": "Hermi F. Brito",
"ids": [
"144616403"
]
}
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] | [
"Chemistry"
] | 2,011 | Journal of Luminescence | 131 | 727-731 | [] | 10.1016/J.JLUMIN.2010.11.026 | https://doi.org/10.1016/J.JLUMIN.2010.11.026 | 2070777686 |
|||
ca61ee240f9a5548f402bb9f09608546650d4c76 | Decline in research publications from the United Kingdom in anaesthesia journals from 1997 to 2006 | We undertook this survey to identify the trend in the published output of original research in anaesthesia emanating from the United Kingdom (UK) in a 10‐year period from 1997 to 2006, inclusive. We examined seven major anaesthetic journals for each of the 10 years, and four other specialist journals for the years 1997, 2000, 2003 and 2006. We included papers on experimental research, randomised controlled clinical trials, large observational studies and case series, formal equipment and apparatus assessments, but we excluded editorials, comments, reviews including systematic reviews, special articles, small case series and case reports, questionnaire surveys of clinical practice and correspondence. We found a highly significant reduction in published research output from the UK in the period under study (% change per year; −5.7 (95% CI −7.4 to −4.0), a trend which was significantly different (p < 0.001) from the trend of changes in research publications worldwide (−1.0% change per year; 95% CI −1.7 to 0.0). We discuss the implications of these findings for UK anaesthesia research strategy. | [] | https://semanticscholar.org/paper/ca61ee240f9a5548f402bb9f09608546650d4c76 | [] | [
{
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"name": "R. Sebastian",
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{
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"Medicine"
] | 2,008 | Anaesthesia | Anaesthesia | 63 | [
"Medline"
] | 10.1111/j.1365-2044.2008.05475.x | https://doi.org/10.1111/j.1365-2044.2008.05475.x | 18289233 | 2142385646 |
||
013c07df2447d3ae2daeabe94211021790227e94 | Stimuli-Responsive Biomaterials for Drug Delivery to Improve Cancer Immunotherapy and Chronic Wound Healing | Sequential delivery of biomolecules is very important as many biologics underlying injury and disease follow an orderly and sequenced series of events. Here we developed and introduced for the first time a dual compartment biomaterial system with an outer compartment made of gelatin and inner compartment that is a ferrogel which can be magnetically stimulated in order to provide on-demand, sequential delivery of multiple bio-instructive payload. We studied the potential application of this dual-compartment biomaterial system in different therapeutic contexts that may benefit from on-demand sequential deliveries, such as in cancer immunotherapy and in chronic wound healing. Chronic wounds can be a result of arrest in the inflammation phase of healing. Although inflammation critically initiates repair and helps clear infections, a prolonged inflammatory reaction can cause considerable harm to the injury site. After an appropriate duration of inflammation, this inflammatory response can be shifted to a more pro-healing response through the delivery of cytokines like interleukin 4 (IL-4) and interleukin 10 (IL-10). These anti-inflammatory cytokines alter the phenotype of macrophages from pro-inflammatory (M1) to anti-inflammatory (M2), suggesting a potentially powerful drug delivery strategy if these cytokines can be delivered in a delayed manner. We hypothesize that the transition of macrophage phenotype from proinflammatory (M1) to anti-inflammatory (M2) can be controlled through sequenced delivery of interferon gamma (IFN-γ), followed by IL-4 and/or IL-10. The goal of this research was to develop a wound-healing hydrogel system that initially delivers proinflammatory IFN-γ, followed by magnetically triggered delivery of pro-healing (antiinflammatory) IL-4 and/or IL-10. Our biomaterial system was composed of twocompartments: (1) a porous gelatin outer compartment designed to recruit macrophages and establish an initial pro-inflammatory (M1) phenotype, and (2) a magnetically responsive alginate inner compartment which was designed to deliver IL-4 and/or IL-10 when magnetically triggered to shift the response to anti-inflammatory by promoting (M2) phenotype. We showed that we can have fast release of IFNg (Promotes M1 phenotype) and MCP-1 (recruits macrophages) initially from the outer compartment while holding on to IL4 and IL10 that is loaded in the ferrogel and have them burst release when applying the magnetic field. Biomaterial-based cancer immunotherapy strategies require materials capable of recruiting dendritic cells (DCs) and reprogramming them with cancer antigen and danger signal. This strategy requires the implantation of a biomaterial that is loaded with DC recruitment factors, danger signals, and cancer antigen. This co-delivery of danger signal and antigen results in DC activation and homing of cancer-antigen-presenting DCs to the lymph nodes, subsequently triggering an anti-tumor immune response from the host. However, danger signals and antigen diffuse out of the biomaterial while DCs are being actively recruited to the biomaterial. This may result in lower concentrations of these necessary reprogramming agents by the time DCs are recruited and consequently, lower quantities of activated DCs, and a reduced anti-tumor immune response. It is possible that sequential release of DC recruitment and reprogramming factors will enhance the number of reprogrammed DCs over simultaneous release, leading to improved anti-cancer immune responses. In order to test this, a material system with unique delivery capabilities must be developed. Therefore, we designed a biomaterial system capable of first recruiting DCs by initially releasing DC recruitment factors from outer compartment. This biomaterial can deliver reprogramming agents (i.e., cancer antigen) when magnetically stimulated only after a substantial population of DCs has been recruited. The results showed that we were able to deliver GM-CSF (DC recruitment factor) initially from the outer compartment followed by delivering HSP27 (model cancer antigen) when stimulated in the magnetic field | [] | https://semanticscholar.org/paper/013c07df2447d3ae2daeabe94211021790227e94 | [
"https://digitalcommons.uri.edu/cgi/viewcontent.cgi?article=1825&context=oa_diss"
] | [
{
"name": "Anita E. Tolouei",
"ids": [
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]
}
] | [] | [
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] | [
"Medicine"
] | 2,018 | [] | 10.23860/DISS-TOLOUEI-ANITA-2018 | https://doi.org/10.23860/DISS-TOLOUEI-ANITA-2018 | 2907041296 |
||||||
735364710a03a53371e6bc782403a681999cfb56 | Light/dark regulation of higher plant nitrate reductase related to hysteresis and calcium/magnesium inhibition | Examination of nitrate reductase (NR, EC 1.6.6.1) activity in crude extracts made from squash leaves before and after a light/dark transition, indicates the existence of two different forms of nitrate reductase; a ‘light form’ with a pH optimum of 7.8 that is not inhibited by calcium or magnesium, and a ‘dark form’ with a pH optimum of 7.6 that is strongly inhibited by calcium or magnesium. The same properties also characterise purified NR. The ‘light and dark forms’ of NR correspond to the two kinetically different forms of purified NR showing (1) linear product formation and (2) delayed product formation, i.e. hysteretic behaviour. | [] | https://semanticscholar.org/paper/735364710a03a53371e6bc782403a681999cfb56 | [
"https://eurekamag.com/pdf/002/002423638.pdf"
] | [
{
"name": "Cathrine Lillo",
"ids": [
"4641723"
]
}
] | [
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] | [
"Chemistry"
] | 1,994 | Physiologia Plantarum | 91 | 295-299 | [] | 10.1111/J.1399-3054.1994.TB00434.X | https://doi.org/10.1111/J.1399-3054.1994.TB00434.X | 2039372276 |
|||
8f96b64360f7d17e100394b49cfe47f277adb75f | A golden anniversary: cattle twins and immune tolerance. | 0 CCASIONALLY a chance observation jump-starts a whole field of science. The discovery of immune tolerance and the recognition of self and nonself is such an event. It started with a 1944 letter from a cattle breeder in Maryland to the University of Wisconsin immunogenetics laboratory, reporting a curious pair of twin calves, unusual in having different fathers. RAY OWEN, a postdoctoral fellow in the laboratory and already interested in blood groups of cattle twins, thought they would provide an interesting opportunity for blood group analysis, so blood samples were sent to him. In the thirties and forties, the genetics of blood cell antigens was an active field for investigation. It was then a popular view among geneticists that antigens, because of their simple inheritance, might be immediate gene products. For this reason, they might provide an insight into the nature of that maddeningly elusive entity, the gene. In pursuit of this possibility, new blood types were actively sought in various species, including Homo supiens and Bos taurus. By the early 1940s, 40 different antigenic specificities had been identified in cattle. The world leader in cattle blood groups was the immunogenetics laboratory at the University of Wisconsin, founded by L. J. COLE and M. R. IRWIN (OWEN 1989). There was sometimes uncertainty about paternity in cattle, and when valuable animals were involved, that could be an important economic issue. Breeders and breed associations welcomed blood groups as a foolproof way of identifjmg sires. The immunogenetics laboratory provided valuable information and the breed associations provided financial support, vitally important in those pre-NIH/NSF days. It was a win-win situation. The events that led to the letter involved a Guernsey cow with twin calves. She had been properly mated to a Guernsey bull, but shortly afterward a lustful Hereford escaped from a neighboring area and got into the act. The color patterns of the calves showed clearly that the twins had different fathers. Blood analysis revealed that the COW carried (among many others) antigen G. The Guernsey bull had antigens S and X2, while the Hereford bull had R and 1’. | [] | https://semanticscholar.org/paper/8f96b64360f7d17e100394b49cfe47f277adb75f | [
"https://ecals.cals.wisc.edu/wp-content/uploads/sites/4/2014/09/Jim-Crow-Tribute-to-Ray-on-50th.pdf",
"http://www.genetics.org/content/genetics/144/3/855.full.pdf"
] | [
{
"name": "J F Crow",
"ids": [
"12269780"
]
}
] | [
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"4af31f1ac4eca70935172c76270587696fbb4248",
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"76b267cf9b20f724132ef38c2a505e0ac5252ab4",
"3545ab04d2599da4960306f247b3e065a52f4569"
] | [
"56f021ce8c7f49fc51df27daa4f429af2cd6db4a",
"dc943f57093f0b4edbdd461ac4d9f15923724297",
"fbcde5bb1678ae60764fc7ec8f044f168d2e6880",
"39f3c6950febee611212f82fe7f2b5efcde367d2",
"d5a59b9165be8bc50d71d0f551e85d7db62ba564"
] | [
"Biology",
"Medicine"
] | 1,996 | Genetics | Genetics | 144 3 |
855-9
| [
"Medline"
] | 8913732 | 2148312232 |
|||
7d96fbe7135f990708a3720f9c80b5603dd7823c | The critical issues affecting the introduction of Health Management Information Systems in developing countries in Africa | Universiteit van Amsterdam Faculteit Natuurwetenschappen Wiskunde en Informatica en Faculteit Economie en Bedrijfskunde " Change is hard because people overestimate the value of what they have, and underestimate the value of what they may gain by giving that up. " Management summary In the countries of Tanzania, Mali, Zambia and Uganda information systems are being introduced in hospitals in the form of health management information systems. But with a lack of relevant research done in these countries about the introduction of technologies like information systems there is not much to go by. This research will therefore be done in support of the belief that a convincing and operational framework for assessing health system performance is vital for the work of governments, development agencies and multilateral institutions. The international Institute for Communication and Development (IICD) works in 9 countries in Africa and Latin America. IICD has since 1998 been supporting partner organizations with the introduction of Information and Communication Technologies (ICT) for development and poverty alleviation, amongst others in the health sector. For the past years they have been supporting projects in Mali, Tanzania, Uganda and Zambia implementing systems into healthcare. IICD sees the importance of a decentralized system for health information management and wants to take stock of the achievements of projects that have been implementing information systems, gather experiences and lessons learnt and identify challenges for introducing and using information system (IS) in healthcare. This is why together with IICD this research wants to identify the issues that have to be considered when implementing information systems in the form of a health management information system in hospitals on the district level in the countries supported by IICD. This, in support of the belief, that a convincing and operational framework for assessing health system performance is vital for the work of governments, development agencies and multilateral institutions. According to the definition in this research a health management information system (HMIS) is designed to integrate data collection, processing, reporting, and use for the improvement of patient health services, effectiveness and efficiency through better management of patient data at all levels of implementation. The output of an HMIS may vary according to the level on which it is being implemented. A HMIS consists of two subsystems: a patient management information system and a hospital management information system (see figure 1).These systems incorporate all the patient data and hospital data with the use … | [] | https://semanticscholar.org/paper/7d96fbe7135f990708a3720f9c80b5603dd7823c | [
"http://www.iicd.org/about/publications/the-critical-issues-affecting-the-introduction-of-health-management-information-systems-in-developing-countries-in-africa/Thesis-HMIS-Nicole-Archangel.pdf",
"http://www.bibalex.org/Search4Dev/files/288388/119340.pdf"
] | [
{
"name": "Nicole Archangel",
"ids": []
}
] | [
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"ff5b4db88e0e206c2d5e54c7de084ff4f380f7e9"
] | [] | 2,008 | [] | |||||||||
50b8d22e254ea2f0b692deeab8126c0696be10cf | An accurate mass and radius measurement for an ultracool white dwarf | Studies of cool white dwarfs in the solar neighbourhood have placed a limit on the age of the Galactic disc of 8–9 billion years. However, determining their cooling ages requires the knowledge of their effective temperatures, masses, radii and atmospheric composition. So far, these parameters could only be inferred for a small number of ultracool white dwarfs for which an accurate distance is known, by fitting their spectral energy distributions in conjunction with a theoretical mass–radius relation. However, the mass–radius relation remains largely untested, and the derived cooling ages are hence model dependent. Here we report direct measurements of the mass and radius of an ultracool white dwarf in the double-lined eclipsing binary SDSS J013851.54−001621.6. We find MWD = 0.529 ± 0.010 M⊙ and RWD = 0.0131 ± 0.0003 R⊙. Our measurements are consistent with the mass–radius relation and we determine a robust cooling age of 9.5 billion years for the 3570 K white dwarf. We find that the mass and radius of the low-mass companion star, Msec = 0.132 ± 0.003 M⊙ and Rsec = 0.165 ± 0.001 R⊙, are in agreement with evolutionary models. We also find evidence that this >9.5 Gyr old M5 star is still active, far beyond the activity lifetime for a star of its spectral type. This is likely caused by the high tidally enforced rotation rate of the star. The companion star is close to filling its Roche lobe and the system will evolve into a cataclysmic variable in only 70 Myr. Our direct measurements demonstrate that this system can be used to calibrate ultracool white dwarf atmospheric models. | [] | https://semanticscholar.org/paper/50b8d22e254ea2f0b692deeab8126c0696be10cf | [
"https://arxiv.org/pdf/1207.5393v2.pdf",
"https://watermark.silverchair.com/426-3-1950.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAlMwggJPBgkqhkiG9w0BBwagggJAMIICPAIBADCCAjUGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMYhOFW--49un2ApOvAgEQgIICBhNBVP_vmsH9_1YgB0G3SyQBbpN_u-MfJE_S2aGtND3R7VU3zbvyuuud1Zs9PKRthuUrrjb7MXGFY2uj9JprBf4Wq4ByeZ6ONaRqVpWyvgTfGopuhSV-3681ylGVCzPmqwQ7zcJGXROoYMvktjgJ9qOP2hnhFft_pEXBGOwNbUk1dwb49y7B_zKv1F0W86ZEqRC7H_HBF7U7HkUFATJqpMI6kuLAU89ibHZcDJC8uZfaXETr1NUGta0lk54DSvHs-4BqItIeJtRX3KOEdyIyXFG4P5PLZ5cp-GS72xoK2vRpvDPNdIUQs9vYPa_ryW9xyOcqgCOXe5Cn2QVd2rBx5YFIACbMREic7wiZXY5qGk3JN_v5uqHqXC4VuPD05npduA90QEzAVE4mx5I-aDUDDXIbuQR_pGxTdcyI5wFSQyZbBBWfnE4x4VUYmFAASI-U1X94aBfxWYfGLO-lA2lzCB9g6DIHR-MbkcyFEBoEsJkHZrcffhsHHkd3lH2eIXxcNZgtao924Re_XqonyOtEZVchMXxlnHoKJnWPCA6yfXjAZNUT2zZf9Dfud-d02AcOo3LU8bzv-uN8xVSPLiprv_i3XV1xQ_Aq_VvkGzLvxNBR008bU4cxUH79sGimE_voQZtO2BQMlvkLnT2QGXcziUEx89HLdSApu5OA6DEQ47_5HYTCe07P",
"https://openresearch-repository.anu.edu.au/bitstream/1885/152490/2/01_Parsons_An_accurate_mass_and_radius_2012.pdf"
] | [
{
"name": "S. G. Parsons",
"ids": [
"7730769"
]
},
{
"name": "B. T. Gansicke",
"ids": [
"69884272"
]
},
{
"name": "T. R. Marsh",
"ids": [
"144944448"
]
},
{
"name": "P. Bergeron",
"ids": [
"102487655"
]
},
{
"name": "C. M. Copperwheat",
"ids": [
"7515149"
]
},
{
"name": "V. S. Dhillon",
"ids": [
"48741383"
]
},
{
"name": "J. Bento",
"ids": [
"144318264"
]
},
{
"name": "S. P. Littlefair",
"ids": [
"8464227"
]
},
{
"name": "M. R. Schreiber",
"ids": [
"48676435"
]
}
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"58650cc0a9fa029ecf704dc901c85db655e71e33"
] | [
"Physics"
] | 2,012 | Monthly Notices of the Royal Astronomical Society | 426 | 1950-1958 | [] | 10.1111/j.1365-2966.2012.21773.x | https://doi.org/10.1111/j.1365-2966.2012.21773.x | 2952761168 |
|||
7021701548bbf474e1df847eb21204b4cf74f9f4 | Fabricating Polyethylene Superhydrophobic Surfaces by Thermal Replica-Molding Using Etched Stainless Steel Surfaces as Templates | Stainless steel smooth surface was first roughed by etching in FeCl_3 containing solution towards working as thermal replica-molding template.Then the polyethylene was thermally pressed onto such etched surfaces.After being cooled to room temperature and stripped off from the templates,the polyethylene replica surfaces were created.Results show that static and dynamic water contact angles are more than 150° and sliding angle is about 5°.Such superhydrophobic surfaces have cauliflower like structure,e.g.,cluster of spine like microstructures.This novel process can be combined with flow-casting process,a main technique for manufacturing plastic films,thus will be meaningful in developing new technique for manufacturing plastic superhydrophobic surfaces in a large scale. | [] | https://semanticscholar.org/paper/7021701548bbf474e1df847eb21204b4cf74f9f4 | [] | [
{
"name": "Zhong Mingqiang",
"ids": [
"94040295"
]
}
] | [] | [] | [
"Materials Science"
] | 2,010 | Journal of Functional Polymers | [] | 2364379561 |
|||||||
c4718a48b30d22e216e4886f29b06461f192021f | Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins | ABSTRACT JC polyomavirus (JCPyV) infection of immunocompromised individuals results in the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). The viral capsid of JCPyV is composed primarily of the major capsid protein virus protein 1 (VP1), and pentameric arrangement of VP1 monomers results in the formation of a pore at the 5-fold axis of symmetry. While the presence of this pore is conserved among polyomaviruses, its functional role in infection or assembly is unknown. Here, we investigate the role of the 5-fold pore in assembly and infection of JCPyV by generating a panel of mutant viruses containing amino acid substitutions of the residues lining this pore. Multicycle growth assays demonstrated that the fitness of all mutants was reduced compared to that of the wild-type virus. Bacterial expression of VP1 pentamers containing substitutions to residues lining the 5-fold pore did not affect pentamer assembly or prevent association with the VP2 minor capsid protein. The X-ray crystal structures of selected pore mutants contained subtle changes to the 5-fold pore, and no other changes to VP1 were observed. Pore mutant pseudoviruses were not deficient in assembly, packaging of the minor capsid proteins, or binding to cells or in transport to the host cell endoplasmic reticulum. Instead, these mutant viruses were unable to expose VP2 upon arrival to the endoplasmic reticulum, a step that is critical for infection. This study demonstrated that the 5-fold pore is an important structural feature of JCPyV and that minor modifications to this structure have significant impacts on infectious entry. IMPORTANCE JCPyV is an important human pathogen that causes a severe neurological disease in immunocompromised individuals. While the high-resolution X-ray structure of the major capsid protein of JCPyV has been solved, the importance of a major structural feature of the capsid, the 5-fold pore, remains poorly understood. This pore is conserved across polyomaviruses and suggests either that these viruses have limited structural plasticity in this region or that this pore is important in infection or assembly. Using a structure-guided mutational approach, we showed that modulation of this pore severely inhibits JCPyV infection. These mutants do not appear deficient in assembly or early steps in infectious entry and are instead reduced in their ability to expose a minor capsid protein in the host cell endoplasmic reticulum. Our work demonstrates that the 5-fold pore is an important structural feature for JCPyV. | [] | https://semanticscholar.org/paper/c4718a48b30d22e216e4886f29b06461f192021f | [] | [
{
"name": "Christian D S Nelson",
"ids": [
"39690538"
]
},
{
"name": "Luisa J Ströh",
"ids": [
"5167454"
]
},
{
"name": "Gretchen V Gee",
"ids": [
"34810236"
]
},
{
"name": "Bethany A O'Hara",
"ids": [
"1393675151"
]
},
{
"name": "Thilo Stehle",
"ids": [
"49736496"
]
},
{
"name": "Walter J Atwood",
"ids": [
"4820356"
]
}
] | [
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"af1c8b2f175f3db3039178d47caea0e4d6cf18cc",
"9eff510f678cbefe037f9367c7615b7994966783"
] | [
"Biology",
"Medicine"
] | 2,015 | Journal of Virology | Journal of Virology | 89 | 3910 - 3921 | [
"Medline"
] | 10.1128/JVI.00089-15 | https://doi.org/10.1128/JVI.00089-15 | 25609820 | 2024629009 |
|
4baccaedbca1d9ceda88c58dcdc48852ede0a8c8 | Wound management, dressings and bandages | This chapter is designed to give information on the normal wound healing process; assessment of the wound patient and wounds; types of wound and wound features; wound classification; types and methods of wound closure and open wound management; types and management of wound drains; complications of wound healing; functions and types of wound dressings, bandages, casts and splints; management of dressings, bandages and casts, and care of the patient. | [] | https://semanticscholar.org/paper/4baccaedbca1d9ceda88c58dcdc48852ede0a8c8 | [] | [
{
"name": "Clare Bryant",
"ids": [
"48208877"
]
},
{
"name": "Dominic Phillips",
"ids": [
"121963712"
]
}
] | [
"e61368eb25a5853f1da8fda39134ae196bd39e00"
] | [] | [
"Medicine"
] | 2,007 | 371-398 | [] | 10.22233/9781910443064.14 | https://doi.org/10.22233/9781910443064.14 | 2883350130 |
|||||
ffa7e8a7744e8b61253b84b6f38e04bcee577f2a | Aspects of long time behaviour of solutions of nonlinear Hamiltonian evolution equations | In this paper we will be mainly concerned with the behaviour of solutions of (space periodic) nonlinear wave equations
$$u_{tt} = \Delta u + p(u;t,x)\,\,\,\,(x \in \text{T}^d )$$
(1)
and nonlinear Schrodinger equations
$$ - iu_t = - \Delta u + V(x)u + \frac{\partial } {{\partial \bar u}}G(u,\bar u;t,x)\,\,\,(x \in \text{T}^d ).$$
(2)
Most of the techniques used have a wider range of applicability however. | [] | https://semanticscholar.org/paper/ffa7e8a7744e8b61253b84b6f38e04bcee577f2a | [] | [
{
"name": "J. Bourgain",
"ids": [
"48758908"
]
}
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"4e78a63b343312b923e81adccbb1be5b6d69f50e"
] | [
"f702785eb336192b222ed8b0a830c0fcdb91828c",
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"d331aa8e490665dca482771a6e6393caf879d121",
"dc0e064cb395bd9880bdc4d3d3705bffea5ebbd2",
"bbd97b1aa161b62417bb11ec7a9cc305c302dba8",
"000b72fe80fd0c33167fa87a0abf6c0c45b4e298"
] | [
"Mathematics"
] | 1,995 | Geometric & Functional Analysis GAFA | 5 | 105-140 | [] | 10.1007/BF01895664 | https://doi.org/10.1007/BF01895664 | 2095383808 |
|||
e546fa1eb485774e14cba2d04943194b033fd9b9 | [Heterogeneity of gastrin-containing G-cells and its expression in gastric adenocarcinomas and endocrine tumors]. | The heterogeneity of gastrin-containing G cells present in human gastric mucosa has been examined immunohistochemically. Calcitonin gene-related peptide (CGRP), calcitonin and human chorionic gonadotropin (hCG)-immunoreactivity were detected in about 500, 20 and 10 cells pro 1,000 G cells, respectively, these findings supporting the "one cell, multi-hormone theory". Gastrin, calcitonin immunoreactive tumor cells were demonstrated in 13%, 3% of the antral adenocarcinomas and 17% and 10% of antral endocrine tumors, but they were not found in fundic adenocarcinomas and endocrine tumors. Cell hybridization between the tumor cell and the G-cell might be a possible mechanism for the occurrence of gastric and calcitonin in the gastric tumors. HCG-immunoreactive tumor cells were detected in 27% of antral adenocarcinomas, and in 24% of the fundic adenocarcinomas, and the production of hCG by gastric tumor cells might be based on the gene expression during carcinogenesis, regardless of the tumor localization. | [] | https://semanticscholar.org/paper/e546fa1eb485774e14cba2d04943194b033fd9b9 | [] | [
{
"name": "H Ito",
"ids": [
"47800832"
]
},
{
"name": "J Hata",
"ids": [
"48923749"
]
},
{
"name": "H Yokozaki",
"ids": [
"6072718"
]
},
{
"name": "E Tahara",
"ids": [
"41072722"
]
}
] | [
"7584389ffd722257c5cc6de1ed110a6cf7994bad"
] | [] | [
"Biology",
"Medicine"
] | 1,987 | Gan no rinsho. Japan journal of cancer clinics | Gan no rinsho. Japan journal of cancer clinics | 33 10 |
1266-73
| [
"Medline"
] | 3499529 | 2416277361 |
|||
49f344c3f3f6b45c340b73848f7b3011362218a5 | Structure to self-structuring: infrastructures and processes in neurobehavioural rehabilitation. | INTRODUCTION
The importance of structure in post-acute brain injury rehabilitation is repeatedly mentioned in clinical practice. However, there has been little exploration of the key elements of structure that promote greater levels of functioning and emotional/behavioural stability and how these elements are optimally integrated within the infrastructure of a rehabilitation service.
OBJECTIVES
The nature of structure and why it is helpful is explored initially. Thereafter, the processes involved in transition from externally supported structure to the client 'self-structuring' are described. The infrastructure for facilitating these transitional processes are considered in terms of the design of services for systemic neurorehabilitation encompassing environmental factors (e.g. living environments, vocational and recreational options, step-up services and social milieus), therapeutic alliances (rehabilitation professionals, family, friends), organisational structures (service delivery, rehabilitation coaching, transdisciplinary teams) and rehabilitation philosophies and practice.
CONCLUSION
It is concluded that the process of supporting individuals to transition from the 'structure' of the environment and other people towards self-structuring skills is a critical process in rehabilitation. This is reliant upon a comprehensive and robust organisational infrastructure that can successfully and flexibly integrate the core elements of structure across a transitional pathway towards increased independence and self-structuring. | [] | https://semanticscholar.org/paper/49f344c3f3f6b45c340b73848f7b3011362218a5 | [] | [
{
"name": "Howard F Jackson",
"ids": [
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]
},
{
"name": "Gemma Hague",
"ids": [
"12350341"
]
},
{
"name": "Leanne Daniels",
"ids": [
"7274550"
]
},
{
"name": "Ralph Aguilar",
"ids": [
"119996744"
]
},
{
"name": "Darren Carr",
"ids": [
"153371653"
]
},
{
"name": "William Kenyon",
"ids": [
"46445117"
]
}
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] | [
"Medicine",
"Psychology"
] | 2,014 | NeuroRehabilitation | NeuroRehabilitation | 34 4 |
681-94
| [
"Medline"
] | 10.3233/NRE-141082 | https://doi.org/10.3233/NRE-141082 | 24820170 | 35381593 |
|
fb4f14ebdba633fdd99b48b16495a5c07dc2e08a | Neural Network Matrix Factorization | Data often comes in the form of an array or matrix. Matrix factorization techniques attempt to recover missing or corrupted entries by assuming that the matrix can be written as the product of two low-rank matrices. In other words, matrix factorization approximates the entries of the matrix by a simple, fixed function---namely, the inner product---acting on the latent feature vectors for the corresponding row and column. Here we consider replacing the inner product by an arbitrary function that we learn from the data at the same time as we learn the latent feature vectors. In particular, we replace the inner product by a multi-layer feed-forward neural network, and learn by alternating between optimizing the network for fixed latent features, and optimizing the latent features for a fixed network. The resulting approach---which we call neural network matrix factorization or NNMF, for short---dominates standard low-rank techniques on a suite of benchmark but is dominated by some recent proposals that take advantage of the graph features. Given the vast range of architectures, activation functions, regularizers, and optimization techniques that could be used within the NNMF framework, it seems likely the true potential of the approach has yet to be reached. | [] | https://semanticscholar.org/paper/fb4f14ebdba633fdd99b48b16495a5c07dc2e08a | [
"http://arxiv.org/pdf/1511.06443v2.pdf",
"http://arxiv.org/abs/1511.06443",
"https://arxiv.org/pdf/1511.06443v2.pdf",
"http://arxiv.org/pdf/1511.06443v1.pdf"
] | [
{
"name": "Gintare Karolina Dziugaite",
"ids": [
"2533850"
]
},
{
"name": "Daniel M. Roy",
"ids": [
"39331522"
]
}
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] | [
"Mathematics",
"Computer Science"
] | 2,015 | ArXiv | ArXiv | abs/1511.06443 | [
"DBLP"
] | 2177562712 |
|||||
4c70881956d6784f14c9dd43440d25624152dfdd | Significance of the mass-compression effect of postlaminectomy/laminotomy fibrosis on histological changes on the dura mater and nerve root of the cauda equina: an experimental study in rats | PurposeThe precise mechanism and pathological role of postlaminectomy/laminotomy fibrosis (PLF) in postoperative neurological deficits have not been established. Many studies use magnetic resonance imaging (MRI) to prove that there is no consistent correlation between PLF and postoperative neurological deficits and back pain (PNDBP). Therefore, we assumed that the direct-compression effect may not be the only factor but that other neurological deficits associated with pathological mechanisms should exist and need more investigation. The purpose of this study was to compare over time the differences and changes in histopathological properties of PLF in rats.MethodsWe used a rat model with walking-track analysis for neurologic evaluation, grading scale to evaluate PLF, histomorphometric measurements of dura sac diameter, and histological tissue reactions (dura mater and spinal rootlets) juxtaposed to the postlaminectomy/laminotomy defect. The 54 adult Sprague–Dawley rats were divided into laminotomy (n = 18), laminectomy (n = 18), and sham-operation groups (n = 18). All groups were subdivided into three equal subgroups based on different postoperative time points (1, 2, and 3 months). All sections of vertebral column were stained with hematoxylin and eosin and with Masson’s trichrome.ResultsThe results showed that only a slight compression effect reflected by nonsignificant changes in the maximum anterior-posterior diameters within the dura sac, in the walking tract test, and increased grades of PLF over time. In addition, significant pathological inflammatory changes, such as thickening of the dura mater, axonal swelling, and neovascularization, were found in the post-laminectomy/laminotomy groups at each time point.ConclusionLaminectomy-/laminotomy-related inflammation may lead to PLF, and these pathological changes may be the main cause of postoperative neurological deficits. These findings show that research on preventing PLF should include perioperative modulation of inflammatory reactions induced by laminectomy/laminotomy. | [] | https://semanticscholar.org/paper/4c70881956d6784f14c9dd43440d25624152dfdd | [] | [
{
"name": "Cheng-Yi Wu",
"ids": [
"2790954"
]
},
{
"name": "I-Ming Jou",
"ids": [
"46374291"
]
},
{
"name": "Wan-Sheng Yang",
"ids": [
"16283828"
]
},
{
"name": "Cheng-Chang Yang",
"ids": [
"2077200"
]
},
{
"name": "Lin-Yu Chao",
"ids": [
"7600824"
]
},
{
"name": "Yi-Hung Huang",
"ids": [
"49866488"
]
}
] | [
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] | [
"Medicine"
] | 2,014 | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | Journal of Orthopaedic Science | 19 | 798-808 | [
"Medline"
] | 10.1007/s00776-014-0590-7 | https://doi.org/10.1007/s00776-014-0590-7 | 25074653 | 1977389188 |
|
9c3b7aa465a9ec9107f737cfe3ec5418a319264f | Comparison of multiple obesity indices for cardiovascular disease risk classification in South Asian adults: The CARRS Study | Background We comparatively assessed the performance of six simple obesity indices to identify adults with cardiovascular disease (CVD) risk factors in a diverse and contemporary South Asian population. Methods 8,892 participants aged 20–60 years in 2010–2011 were analyzed. Six obesity indices were examined: body mass index (BMI), waist circumference (WC), waist-height ratio (WHtR), waist-hip ratio (WHR), log of the sum of triceps and subscapular skin fold thickness (LTS), and percent body fat derived from bioelectric impedance analysis (BIA). We estimated models with obesity indices specified as deciles and as continuous linear variables to predict prevalent hypertension, diabetes, and high cholesterol and report associations (prevalence ratios, PRs), discrimination (area-under-the-curve, AUCs), and calibration (index χ2). We also examined a composite unhealthy cardiovascular profile score summarizing glucose, lipids, and blood pressure. Results No single obesity index consistently performed statistically significantly better than the others across the outcome models. Based on point estimates, WHtR trended towards best performance in classifying diabetes (PR = 1.58 [1.45–1.72], AUC = 0.77, men; PR = 1.59 [1.47–1.71], AUC = 0.80, women) and hypertension (PR = 1.34 [1.26,1.42], AUC = 0.70, men; PR = 1.41 [1.33,1.50], AUC = 0.78, women). WC (mean difference = 0.24 SD [0.21–0.27]) and WHtR (mean difference = 0.24 SD [0.21,0.28]) had the strongest associations with the composite unhealthy cardiovascular profile score in women but not in men. Conclusions WC and WHtR were the most useful indices for identifying South Asian adults with prevalent diabetes and hypertension. Collection of waist circumference data in South Asian health surveys will be informative for population-based CVD surveillance efforts. | [] | https://semanticscholar.org/paper/9c3b7aa465a9ec9107f737cfe3ec5418a319264f | [
"https://researchonline.lshtm.ac.uk/id/eprint/4651014/1/Comparison-of-multiple-obesity-indices-for-cardiovascular-disease.pdf",
"http://researchonline.lshtm.ac.uk/4651014/1/Comparison-of-multiple-obesity-indices-for-cardiovascular-disease.pdf",
"https://ecommons.aku.edu/cgi/viewcontent.cgi?article=1262&context=pakistan_fhs_mc_chs_chs",
"https://open.library.emory.edu/publications/emory:s2rth/pdf/",
"http://mdrf-eprints.in/1035/1/Comparison_of_multiple_obesity_indices_for_cardiovascular_disease_risk_classification_in_South_Asian_adultsThe_CARRS_Study.pdf"
] | [
{
"name": "Shivani A. Patel",
"ids": [
"4376220"
]
},
{
"name": "Mohan Deepa",
"ids": [
"35112328"
]
},
{
"name": "Roopa Shivashankar",
"ids": [
"8597417"
]
},
{
"name": "Mohammed K. Ali",
"ids": [
"144654076"
]
},
{
"name": "Deksha Kapoor",
"ids": [
"8093752"
]
},
{
"name": "Ruby Gupta",
"ids": [
"49007233"
]
},
{
"name": "Dorothy Lall",
"ids": [
"39621004"
]
},
{
"name": "Nikhil Tandon",
"ids": [
"144797283"
]
},
{
"name": "Viswanathan Mohan",
"ids": [
"143786000"
]
},
{
"name": "M. Masood Kadir",
"ids": [
"1957804"
]
},
{
"name": "Zafar Fatmi",
"ids": [
"3183867"
]
},
{
"name": "Dorairaj Prabhakaran",
"ids": [
"145574924"
]
},
{
"name": "K. M. Venkat Narayan",
"ids": [
"153599397"
]
}
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] | [
"Medicine"
] | 2,017 | PloS one | PLoS ONE | 12 | [
"Medline"
] | 10.1371/journal.pone.0174251 | https://doi.org/10.1371/journal.pone.0174251 | 28448582 | 2607686031 |
||
7b7df8c1b1e5704e989c1e1999143e3b79f1c622 | Warplane EME Adaptability Prediction Technology Based on Multiple Physical Fields Union | As the complexity of the battlefield EME and radiation power is biger, the formation and aircraft platform in calculation of battlefield electromagnetic environment adaptability and forecast is also more and more important. In this paper, by combining a variety of EM numerical simulation methods, electromagnetic environment, characteristics of antenna radiation, isolation of antennas is studied on. | [] | https://semanticscholar.org/paper/7b7df8c1b1e5704e989c1e1999143e3b79f1c622 | [] | [
{
"name": "Yan Wang",
"ids": []
},
{
"name": "Xuefeng Qi",
"ids": [
"50121243"
]
},
{
"name": "Guoshuai Zhen",
"ids": [
"1400580003"
]
},
{
"name": "Wenjie Zhang",
"ids": [
"50549741"
]
},
{
"name": "Yu Mao",
"ids": [
"48088109"
]
}
] | [] | [
"66a54df64071195ac7b67eea958d37b930c05332",
"164980a2543245cb371cfa78195913174c4091f1",
"e34455a5f5ad090e20c6f77dea19a71d9d581eca"
] | [
"Computer Science"
] | 2,019 | 2019 IEEE 2nd International Conference on Electronic Information and Communication Technology (ICEICT) | 2019 IEEE 2nd International Conference on Electronic Information and Communication Technology (ICEICT) | 1-4 | [] | 10.1109/ICEICT.2019.8846355 | https://doi.org/10.1109/ICEICT.2019.8846355 | 2982335289 |
|||
96115f2823d005a253c1cb56738af8f31a9db5cd | Free radicals from single crystals of 2′-deoxyuridine | Abstract X-irradiation of single crystals of 2′-deoxyuridine (UdR) between 8 K and room temperature gives rise to a variety of different radical structures, seven of which are described here. The dominant low-temperature species are the π ∗ anion on the uracil base and alkoxy radicals. The former is characterized by the usual α-proton interaction at C6(−1.24, −0.83, −2.1 mT) but displays additional interactions with the nitrogens on N1 and N3. For the alkoxy radicals, there is marked variability in structures yielding two primary and one secondary species. Upon warming, an α-hydroxy alkyl radical at C5′ of the deoxyribose grows in showing an a coupling (−0.84, −1.42, −2.36 mT), a β interaction (3.1 mT) and an exchangeable OH coupling ∼0.3 mT). Upon irradiation at room temperature, a 5-yl and a 6-yl radical are the main radical centers both formed by net gain of a hydrogen at the 6 and 5 position of the base, respectively. Besides an a coupling, the former species shows inequivalent β protons (3.9, 4.9 mT) and interaction with the N3H group. The 6-yl radical has equivalent β couplings of 3.3 mT. Storage of crystals for several months at 300 K results in loss of both 5- and 6-yl radicals and formation of two different species, one characterized by two β-type interactions (4.2, 1.8 mT) and one exhibiting an α-type coupling (−0.53, −1.88, −0.98 mT). Tentative assignments for these species are given and the solid-state radiation chemistry of uracil derivatives with respect to nucleic acid radiation damage is discussed. | [] | https://semanticscholar.org/paper/96115f2823d005a253c1cb56738af8f31a9db5cd | [] | [
{
"name": "K Voit",
"ids": [
"144085584"
]
},
{
"name": "J Hüttermann",
"ids": [
"9922892"
]
}
] | [
"54a77dc31501f55de5aad348de29cece479d0e50",
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"bec1baec9329098a740afbe1c7c69193dfa2c911"
] | [
"Chemistry"
] | 1,983 | Journal of Magnetic Resonance | 55 | 225-246 | [] | 10.1016/0022-2364(83)90235-4 | https://doi.org/10.1016/0022-2364%2883%2990235-4 | 1999039502 |
|||
76433a225423a2eb86c4d8171e70617fa455c967 | The Effect of CRT Screen Design on Learning. | Two computer assisted instruction programs tested the effects of plain and enhanced screen designs with or without information about those designs and task-type on time and learning. Subjects were 140'fourth grade students in Lincoln, Nebraska who had extensive prior experience with computers. The enhanced versions used headings,directive cues, running heads, and graphic devices to organize and structure the content. One program required learners to perform a memorization task, while the second involved concept acquisition and concept application. The information provided with one version of the memorization lesson described the purpose of the enhanced features and instructed the students to use those features while studying. Although the plain screen versions were found to be equal to the enhanced versions in learning, descriptions of text enhancements reduced lesson time when one of the enhancements provided the learner with program control options. The text is supplemented by 5 figures, 7 tables, and 25 references. (EW) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** C.f. DEPARTMENT OF EDUCATION Offics of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) )(This document has been reproduced as received from the Person or organization originating it 0 Minor Changes have been made to improve reproduction Quality Points of view or opinionsstatedinthisdoci merit do not necessarily represent official OERI position or policy, The Effect of CRT Screen Design on Learning | [] | https://semanticscholar.org/paper/76433a225423a2eb86c4d8171e70617fa455c967 | [
"https://files.eric.ed.gov/fulltext/ED295640.pdf"
] | [
{
"name": "R. Scott Grabinger",
"ids": [
"1870350"
]
},
{
"name": "Starleen Albers",
"ids": [
"122840642"
]
}
] | [
"4b1bbe63e6b9f8bfd7f94c13614de53eac19daa2",
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"57b54932c3621d65b67f40188669cf13fef93724"
] | [
"45f1d9305fd94bb638c30f5e8066bd502d432630",
"7f5ab42991caba1053a30f31ef272b16bc8d0200",
"cc160d53598f433af303c666c347d3ddc57d82c0",
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"7fc1d1af5eabcd4a4245b589b77307999723927d",
"b3e9935bc2e141fdfb181cdad86ed704b24e3260",
"a69813573b7845f9c2b13350674831b604260a18",
"4319f1fe76f22639dfb41f16b4cb1c6f53562bf4",
"85a95e988840b9e8f429be4a944ba3a260ff5dd9",
"a79f17b45d46fe448507a472371ce37888259e49",
"9a461650892a1ce31e4409b15e8a7dffbed151c9",
"2c0a36b9b96b82ac7ebe4ad72ac688be251cbe3b",
"bfc2240b2cb9e4625f57240e87a727344d11818d",
"36ac251fb86842e5272bb1f56fc40200b6ddeabe",
"e39f45e143b5a559f375920992cb7a95814e66fa",
"6d8c24c67b2f743f1a058436d9ee5b4197de4ea2",
"2258efb63cb94729b0eacf143546e9fa7815de27",
"83ff7e3e4667d5633bff06354cf6ba5c67a9322f"
] | [
"Computer Science"
] | 1,988 | [] | 10.1111/J.1937-8327.1989.TB00422.X | https://doi.org/10.1111/J.1937-8327.1989.TB00422.X | 2141934004 |
||||||
0c5b87e2b3d2a95461e6fa316a5cea0b6f306e5f | Objective: Industrial Peace | Industrial strife leaves its scars upon the relations between employers and employees. When strikes occur, distrust and antagonisms are engendered which persist after the strikes are over. Strikes, too, curtail production. A strike in one plant often causes work stoppages in other plants where industrial peace prevails. Strikes cause employees to lose wages which they may never recover even though they gain increases in their rates of pay. Strikes upset the economy of the communities in which they occur. The "butcher, the baker, and the candlestick maker" lose business if the striking employees cannot buy. Strikes weaken the finances of the companies in which they occur. Stockholders face possible reductions in their dividends. Strikes, particularly in the basic industries and utilities, jeopardize the rights of the public. The cutting off of electricity, gas, transportation, milk, and fuel are serious matters. Strikes and other forms of industrial strife must give way to industrial peace. But we cannot countenance industrial peace "at any price." Industrial peace must not be gained at the expense of our democratic way of life, nor by the abandonment of our American free enterprise system. Industrial peace must be achieved by democratic means, in some countries industrial strife has been outlawed but only through the compulsion of autocratic government. While we recognize the evils of industrial strife, we have not clearly identified the underlying causes. I shall endeavor to throw some illumination upon the causes, as I see them, by reference to outstanding eveners and developments in the period of about 30 years which commenced with the First World War. (Author's abstract courtesy EBSCO.) | [] | https://semanticscholar.org/paper/0c5b87e2b3d2a95461e6fa316a5cea0b6f306e5f | [] | [
{
"name": "E. O. Shreve",
"ids": [
"119374942"
]
}
] | [
"dd69206e08b1f426805001c7838cf6cebbf9ddd0"
] | [] | [
"Economics"
] | 1,948 | Industrial & Labor Relations Review | 1 | 431 - 442 | [] | 10.1177/001979394800100307 | https://doi.org/10.1177/001979394800100307 | 1964827082 |
|||
10f21104432051862cdaa5c6662f1ade2cb38f9e | Development and evaluation of a fully automated monophasic action potential analysis program | A fully automated program has been developed for analysing digitised cardiac monophasic action potentials (MAPs) of several animal species. Under diverse conditions, the program’s performance is evaluated by comparison with high-resolution manual analysis of action potential duration, MAP detection, baseline and plateau determination. For each variable, the differences between both forms of analysis are categorised according to species (rabbit, dog or baboon), intervention (control, sematilide or LY-190147), rhythm source (sinus or paced), and rates. They are then examined using ANOVA (null hypothesis: no difference between methods for any category). Intra-group differences are significant for baseline selection (p<0.05), and treatment effects are significant (p<0.05) for one species (baboon). However, the differences found are negligible when compared with expected measurement errors. Thus the program reliably detects and accurately analyses MAPs, independent of species, drug or pacing. The program’s strength is its use of simple heuristic algorithms to identify and profile MAP signals while rejecting spurious transients. These algorithms focus on the procedural aspects of automatic MAP detection and validation, with minimum use of complex mathematics. The program’s estimated throughput exceeds 8200 MAPs min−1 on a 50 MHz i486 DX machine. With available data format conversion packages, signals from almost any data-acquisition source can be analysed. | [] | https://semanticscholar.org/paper/10f21104432051862cdaa5c6662f1ade2cb38f9e | [] | [
{
"name": "D. R. Dickenson",
"ids": [
"8342604"
]
},
{
"name": "D. R. Davis",
"ids": [
"95643341"
]
},
{
"name": "G. N. Beatch",
"ids": [
"4778200"
]
}
] | [
"2ba4f4c243834e15be00f01033bebe2fad357735",
"5506352055a7c81adc598271b6005fb02689c14f",
"34567fc7ab412b3245113fd6151b678c756c63fb",
"e5be95c7d8a93af84ab1c07aae7495a0dbce9e03"
] | [
"4525ec1aa4ad5ce6904aaaeb6848b4b49d9ec502",
"9f743c4bc35ca10bbc3a3596902b65c561677eb1",
"21542aa2b51ac441b51cd015386069cb8e3ab264",
"1c6a03a44841f9e886f35c0a49524468d387fce5",
"e6805887116231d8845fd01a79861deb0cfa1f2f",
"6c52727ab08447c0596eb9968b7d09efb8d42faf",
"cbcef79d92189da1baf745293e023f0440e120c5",
"744bd606316ec3ecde01401645c67922f6f88919",
"6ce6a505db14ff7c9ac43ad2834e1bd1d75d9aed",
"b3dbdbb438ddd0a0fca4ab8dc03b34883998dd63",
"83f071ac7931586840317f3406eb860121194178",
"a777b3da8fb090ea476126024bdf51a7bae483ed",
"299aeba6cf04d58e30207cdf1400d0729795c572",
"a04a543758d423e089e87739fa0abf1d1983d008"
] | [
"Medicine",
"Mathematics"
] | 2,006 | Medical and Biological Engineering and Computing | Medical and Biological Engineering and Computing | 35 | 653-660 | [
"Medline"
] | 10.1007/BF02510974 | https://doi.org/10.1007/BF02510974 | 9538542 | 2088194306 |
|
5e7579255a1a6579db9a2fc09aa1fecf792e84a6 | Long-term safety and efficacy of infliximab therapy in refractory uveitis due to Behçet’s disease | AbstractPurpose To evaluate the long-term safety and efficacy of infliximab therapy for refractory uveitis associated with Behçet’s disease (BD).
Methods We prospectively enrolled six patients who failed to respond to conventional immunosuppressive treatment. Infliximab infusions (5 mg/kg) were administered at weeks 0, 2, 6, and then every 8 weeks. The outcome variables were visual acuity, control of inflammation, reduction of macular edema, tapering of immunosuppressive therapy, and adverse effects.
Results The follow-up period ranged from 16 to 36 months (mean ± SD, 23 ± 7.4 months). The number of infliximab infusions ranged from 10 to 23 (14 ± 4.6). By the 2-month follow-up, all patients had achieved remission, the cystoid macular edema had resolved, and visual acuity had improved dramatically. Throughout the follow-up period, three patients remained attack-free. One patient had one relapse, and another patient had two relapses before the scheduled infusions; all three relapses resolved rapidly after the subsequent infusion. One patient developed five relapses, and infusions at 6-week intervals were necessary to achieve sustained remission. At the end of the follow-up period, visual acuity improved in five patients. Concomitant immunosuppressive therapy was substantially reduced. Antinuclear antibodies developed in two patients who received 17 and 23 infusions. No major adverse effects requiring withdrawal of infliximab were observed.
Conclusion Infliximab is efficient and safe for long-term treatment of refractory uveitis associated with BD. Repeated infusions are required to maintain long-term remission. | [] | https://semanticscholar.org/paper/5e7579255a1a6579db9a2fc09aa1fecf792e84a6 | [] | [
{
"name": "Ahmed M. Abu El-Asrar",
"ids": [
"1404147715"
]
},
{
"name": "Emad B. Abboud",
"ids": [
"2139336"
]
},
{
"name": "Hassan Aldibhi",
"ids": [
"14783886"
]
},
{
"name": "Abdulrahman Al-Arfaj",
"ids": [
"1421882114"
]
}
] | [
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] | [
"Medicine"
] | 2,006 | International Ophthalmology | International Ophthalmology | 26 | 83-92 | [
"Medline"
] | 10.1007/s10792-006-9006-9 | https://doi.org/10.1007/s10792-006-9006-9 | 17031510 | 1994157670 |
|
0ada90b7780a2ff6b69a582efa16a555244f5710 | Obesity and robotic surgery: Associated ventilator indices and perioperative pulmonary complications. | 5596 Background: Robotic surgery has been shown to be feasible in obese patients. However, there remains concern about the safety of robotic surgery in obese women who need gynecologic surgery, as the positioning required for pelvic surgery can exacerbate obesity-related changes in respiratory physiology. Our objective was to evaluate success and complication rates in obese women undergoing robotic gynecologic surgery and to assess variables that may be associated with complications. Methods: A retrospective chart review was performed on 1,035 obese patients who underwent robotic gynecologic surgery at two academic institutions between 2006 and 2012. Primary outcome was pulmonary complications. Secondary outcome was all-cause complications. Univariate logistic regression analysis was used to determine associations between patient baseline variables (age, BMI), operative variables (case length, trendelenburg time), ventilator parameters (tidal volume, peak inspiratory pressure) and complications (pulmonary... | [] | https://semanticscholar.org/paper/0ada90b7780a2ff6b69a582efa16a555244f5710 | [] | [
{
"name": "Weiya Z. Wysham",
"ids": [
"4633520"
]
},
{
"name": "Kenneth H. Kim",
"ids": [
"4568891"
]
},
{
"name": "Jared M. Roberts",
"ids": [
"47605691"
]
},
{
"name": "S. A. Sullivan",
"ids": [
"32862447"
]
},
{
"name": "Sukhkamal Bhullar",
"ids": [
"51902453"
]
},
{
"name": "Dario R. Roque",
"ids": [
"39578829"
]
},
{
"name": "Dominic T. Moore",
"ids": [
"6483929"
]
},
{
"name": "Paola A. Gehrig",
"ids": [
"6165426"
]
},
{
"name": "John F. Boggess",
"ids": [
"2169543"
]
},
{
"name": "Warner K. Huh",
"ids": [
"1733976"
]
}
] | [] | [] | [
"Medicine"
] | 2,014 | Journal of Clinical Oncology | 32 | 5596-5596 | [] | 10.1200/JCO.2014.32.15_SUPPL.5596 | https://doi.org/10.1200/JCO.2014.32.15_SUPPL.5596 | 2439379960 |
|||
ee4ea77581f6cc93f660ce144e16e06df945402f | Characterization of mustard seeds and paste by DART ionization with time-of-flight mass spectrometry. | Direct analysis in real time (DART) is a novel technique with great potential for rapid screening analysis. The DART ionization method coupled with high-resolution time-of-flight mass spectrometry (TOF-MS) has been used for characterization of mustard seeds and table mustard. The possibility to use DART to analyse glucosinolates was confirmed on determination of sinalbin (4-hydroxybenzyl glucosinolate). The DART-TOF-MS method was optimized and validated. A set of samples of mustard seeds and mustard products was analyzed. High-performance liquid chromatography and DART-TOF-MS were used to determine glucosinolates in mustard seeds and compared. The correlation equation between these methods was DART = 0.797*HPLC + 6.987, R(2) = 0.972. The DART technique seems to be a suitable method for evaluation of the quality of mustard seeds and mustard products. | [] | https://semanticscholar.org/paper/ee4ea77581f6cc93f660ce144e16e06df945402f | [] | [
{
"name": "Jana Prchalová",
"ids": [
"144687646"
]
},
{
"name": "František Kovařík",
"ids": [
"14712633"
]
},
{
"name": "Rudolf Ševčík",
"ids": [
"40481210"
]
},
{
"name": "Helena Čížková",
"ids": [
"40161704"
]
},
{
"name": "Aleš Rajchl",
"ids": [
"11299296"
]
}
] | [
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] | [
"Medicine",
"Chemistry"
] | 2,014 | Journal of mass spectrometry : JMS | Journal of mass spectrometry : JMS | 49 9 |
811-8
| [
"Medline"
] | 10.1002/jms.3419 | https://doi.org/10.1002/jms.3419 | 25230177 | 2464975691 |
|
9c452912548c28ec2d455ef064e3c2fafceb2504 | The Application of Slewing Bearing to the Feeding Rotary Trolley | Slewing bearing using in the feeding rotary trolley,can lead to the 360 angle revolving of the material table and support heavy load.Meanwhile,the structure of trolley is more simple and compact.This paper introduces the structural characteristics of slewing bearing as well as the working principle of selection;then,the author points out the direction of development. | [] | https://semanticscholar.org/paper/9c452912548c28ec2d455ef064e3c2fafceb2504 | [] | [
{
"name": "Su Wen-ying",
"ids": [
"9408807"
]
}
] | [] | [] | [
"Engineering"
] | 2,010 | Journal of Henan Mechanical and Electrical Engineering College | [] | 2378247832 |
|||||||
d881d7b4b3788db6f700d635ae9bfb0d50705b9d | Motion patterns in political speech and their influence on personality ratings | Abstract When people form impressions about others, they are mostly influenced by non-verbal cues. Thus, politicians and other leaders are judged by the behavior they display. To analyze the relation between non-verbal behavior and impression formation body movements of politicians giving a speech were transformed into animated stick figures. Subjects then rated the stick-figure movies on the five factor model of personality. Motion analysis revealed that observers associate extraversion, agreeableness, conscientiousness, emotional stability and openness with different motion qualities such as the amount of motion and its flow. Additionally, we found significant correlations between these personality traits and dominant activation of different body parts. The current study underlines that body motion is a powerful signal in human communication. | [] | https://semanticscholar.org/paper/d881d7b4b3788db6f700d635ae9bfb0d50705b9d | [] | [
{
"name": "Markus Koppensteiner",
"ids": [
"1852082"
]
},
{
"name": "Karl Grammer",
"ids": [
"1850299"
]
}
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] | [
"Psychology"
] | 2,010 | Journal of Research in Personality | 44 | 374-379 | [] | 10.1016/J.JRP.2010.04.002 | https://doi.org/10.1016/J.JRP.2010.04.002 | 2052890918 |
|||
f3f50f753455cbc9da522382cc781946b824cc86 | Cloning and sequencing of APXIIA gene of Actinobacillus pleuropneumoniae | The APXⅡA gene of 2 873 bp, which was amplified from Actinobacillus pleuropneumoniae (APP) serotype 7 by PCR, was cloned into the plasmid vector pMD 18-T to construct the recombinant (plasmid). The constructed recombinant plasmid was (analyzed) by restriction enzyme digestion and sequence analysis. The result showed that the cloned gene from APP serotype 7 by us is the full-length target gene and shares 99.7% homology with that from the APP foreign isolate strain M30602. | [] | https://semanticscholar.org/paper/f3f50f753455cbc9da522382cc781946b824cc86 | [] | [
{
"name": "Zhao Wei-ping",
"ids": [
"32873409"
]
},
{
"name": "Lu Zhongxin",
"ids": [
"66242603"
]
},
{
"name": "Chen Zhen-wen",
"ids": [
"31102139"
]
},
{
"name": "Yang Xue-shan",
"ids": [
"72506970"
]
},
{
"name": "Zhao Ping",
"ids": [
"51463559"
]
},
{
"name": "Gao PengCheng",
"ids": [
"66197706"
]
},
{
"name": "Chu Yuefeng",
"ids": [
"67268082"
]
}
] | [] | [] | [
"Biology"
] | 2,004 | [] | 2365757956 |
||||||||
d64b06d5b725def99f4e66baf2864b0a0fb687a2 | Motion-blurred star acquisition method of the star tracker under high dynamic conditions. | The star tracker is one of the most promising attitude measurement devices used in spacecraft due to its extremely high accuracy. However, high dynamic performance is still one of its constraints. Smearing appears, making it more difficult to distinguish the energy dispersive star point from the noise. An effective star acquisition approach for motion-blurred star image is proposed in this work. The correlation filter and mathematical morphology algorithm is combined to enhance the signal energy and evaluate slowly varying background noise. The star point can be separated from most types of noise in this manner, making extraction and recognition easier. Partial image differentiation is then utilized to obtain the motion parameters from only one image of the star tracker based on the above process. Considering the motion model, the reference window is adopted to perform centroid determination. Star acquisition results of real on-orbit star images and laboratory validation experiments demonstrate that the method described in this work is effective and the dynamic performance of the star tracker could be improved along with more identified stars and guaranteed position accuracy of the star point. | [] | https://semanticscholar.org/paper/d64b06d5b725def99f4e66baf2864b0a0fb687a2 | [] | [
{
"name": "Ting Sun",
"ids": [
"144891954"
]
},
{
"name": "Fei Xing",
"ids": [
"145226472"
]
},
{
"name": "Zheng You",
"ids": [
"145055840"
]
},
{
"name": "Minsong Wei",
"ids": [
"8698382"
]
}
] | [
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] | [
"Physics",
"Medicine"
] | 2,013 | Optics express | Optics express | 21 17 |
20096-110
| [
"Medline"
] | 10.1364/OE.21.020096 | https://doi.org/10.1364/OE.21.020096 | 24105556 | 2121345695 |
|
cd3fce629d9b11147397766ce56d297f522cc01e | Design of an application specific instruction set processor for video processing | The ASIP,which features the high efficiency of ASIC and the flexibility of General Purpose Processor,has and will have been popular in video processing domain.A new design of SIMD proccessor,which had an explicit data organization instruction set and special hardware architecture,was presented.The design was synthesised in SIMC 0.18 μm standard CMOS technology,with a frequency of 180 MHz and an area of 12.38 mm2 under the worst working condition.The results show that the processor can improve the efficiency of video processing greatly. | [] | https://semanticscholar.org/paper/cd3fce629d9b11147397766ce56d297f522cc01e | [] | [
{
"name": "Long Guo-qiang",
"ids": [
"119571306"
]
}
] | [] | [] | [
"Computer Science"
] | 2,008 | Mechanical & Electrical Engineering Magazine | [] | 2369797227 |
|||||||
1cb3639e713a0f9d43569f8ac3790ee8db93f00e | Alpha-diimine nickel (II) olefin polymerization catalyst as well as preparation method and application thereof | The invention discloses a novel late transition metal alpha-diimine nickel (II) olefin polymerization catalyst with a symmetrical structure. The catalyst is a didentate coordination compound formed by an alpha-diimine ligand with a symmetrical Schiff base structure and a halogenide of later transition metal nickel (II). In the presence of diethyl aluminium chloride (DEAC) used as a cocatalyst, the coordination compound catalyst of nickel has higher activity for catalyzing ethylene to polymerize, which can reach 107gPE/(mol Ni h Bar), and obtained polyethylene has higher degree of branching, which can reach 114 branched chains per 1,000C. | [] | https://semanticscholar.org/paper/1cb3639e713a0f9d43569f8ac3790ee8db93f00e | [] | [
{
"name": "刘玉凤",
"ids": [
"89593735"
]
},
{
"name": "梅铜简",
"ids": [
"92596302"
]
},
{
"name": "王学虎",
"ids": [
"66035345"
]
},
{
"name": "袁建超",
"ids": [
"91608509"
]
}
] | [] | [
"c4dd6f4e824d951d0de8a170b3bc06c24bb9e273"
] | [
"Chemistry"
] | 2,010 | [] | 2800873455 |
||||||||
72bd789df9ef1655c103b51238e5f161b8e30641 | The light source module and a light source system | A light source module comprises: a primary light unit (10) that radiates primary light; a light converting unit (20) that receives the primary light, converts the primary light into secondary light and radiates the secondary light; a light detecting unit (30) that detects light; a plurality of optical fibers (40) that guide light; and a beam splitting unit (50) that is equipped with a plurality of primary terminals and a plurality of secondary terminals, wherein the light entering in one of the primary terminals is radiated from the plurality of secondary terminals, and the light entering in one of the secondary terminals is radiated from the plurality of primary terminals. The primary light unit and the light detecting unit are arranged on the primary terminal side of the beam splitting unit, and the light converting unit is arranged on the secondary terminal side of the beam splitting unit such that, via the plurality of optic fibers, primary light can be guided from the primary light unit to the light converting unit, and secondary light can be guided from the light converting unit to the light detecting unit. | [] | https://semanticscholar.org/paper/72bd789df9ef1655c103b51238e5f161b8e30641 | [] | [
{
"name": "山本英二",
"ids": [
"72471640"
]
},
{
"name": "伊藤毅",
"ids": [
"66534104"
]
},
{
"name": "西尾真博",
"ids": [
"71517407"
]
},
{
"name": "驹崎岩男",
"ids": [
"96180678"
]
}
] | [] | [] | [
"Physics"
] | 2,012 | [] | 2774649016 |
||||||||
174e10d31901295c0c46449dbdbd237bb661c0ba | From Sanskritisation to Hindi-isation and Hindu-isation | It is too early to make a detailed analysis of the general election for the 13th Lok Sabha. The proximate cause of Congress downfall are fairly obvious. The Congress vision of the nation is incomplete, underdeterminate and inconsistent in theory, and gravely dubious in practice. The BJP as a part of the Sangh parivar touches all aspects of our life. Its model of the nation is at variance with the true principles of Vedas. Yet it has potentially tremendous appeal to the caste-conscious, sanskritising Hindu masses. Not too long ago you heard a chorus of lambs: Indira is India. Expect soon a kirtan of hanumans: India is Hindia. | [] | https://semanticscholar.org/paper/174e10d31901295c0c46449dbdbd237bb661c0ba | [] | [
{
"name": "Ranjit Sau",
"ids": [
"103064618"
]
}
] | [
"f47b6ad13b87051d2835088872ebadc764f30336",
"00287107bf035fe06a6d4a666c4335dfe744680b"
] | [] | [
"Sociology"
] | 1,999 | Economic and Political Weekly | [] | 80254795 |
|||||||
37ef85e276118682c80c431adaa1330351edaabe | Poster: Power over data lines for CAN using AMI code | Electronic control units (ECUs) in vehicles are interconnected with each other. Controller area network (CAN) is one of standards for in-vehicle networks and is widely employed. However, much more weight and space of wiring harness among CAN devices have been required as upgrading higher-performance networks. In this paper, we propose power over CAN (PoCAN), which is an implementation method of power over data lines (PoDL) under the review in IEEE P802.3bu, for twisted-pair (TP) cables among CAN devices to remove power lines. Unipolar non-return-to-zero (NRZ) line codes are employed in CAN and include mainly direct current (DC) component in the signals so that power superposed unipolar NRZ codes will not be suitable for PoDL. Bipolar alternate make inversion (AMI) and NRZ line codes are exploited for PoCAN because AMI-NRZ codes do not include DC component. The waveforms of PoCAN are analyzed in bus networks complied by a CAN standard with an analog mixed-signal (AMS) simulator. Moreover, experimental trials are conducted to evaluate frame transmission of PoCAN. The simulation and experimental results show that the proposed PoCAN can achieve the simultaneous transmission of data and DC power in one-pair TP cables. | [] | https://semanticscholar.org/paper/37ef85e276118682c80c431adaa1330351edaabe | [
"https://doi.org/10.1109/VNC.2016.7835948"
] | [
{
"name": "Tatsuki Matsushita",
"ids": [
"8806224"
]
},
{
"name": "Daisuke Umehara",
"ids": [
"2797845"
]
},
{
"name": "Koichiro Wakasugi",
"ids": [
"2879847"
]
}
] | [
"ba2815107a1d28c0cc98bb7ce705dc665bafac74",
"93233004a6385f3c3c6ae3844f377700d2b7bed5"
] | [] | [
"Computer Science"
] | 2,016 | 2016 IEEE Vehicular Networking Conference (VNC) | 2016 IEEE Vehicular Networking Conference (VNC) | 1-2 | [
"DBLP"
] | 10.1109/VNC.2016.7835948 | https://doi.org/10.1109/VNC.2016.7835948 | 2582765292 |
|||
9e260bf1c740862af1b1177d001652ca0d9609e8 | An 18-item standardized Asthma Quality of Life Questionnaire-AQLQ(S) | The purpose of the present study was to examine the validity and reliability of the Asthma Quality of Life Questionnaire-AQLQ(S) in a sample of 160 Greek patients with asthma. Following evidence for sample-specific validity, the AQLQ(S) model was examined through exploratory and confirmatory factor analysis. An 18-item AQLQ(S) with the four factors of symptoms, activity limitations, sleep, and exposure in environmental stimuli fits the data (χ2/df ratio = 2.26, NNFI = 0.92, CFI = 0.94, SRMR = 0.05). The 18-item AQLQ(S) showed a high internal consistency (Cronbach’ a coefficient ranged from 0.83 to 0.96) and high 9-week test-retest reliability (overall r = 0.88, ICC = 0.94). Responsiveness was confirmed throughout 2X2 ANOVA and 2X2 MANOVA, with respect to the total score (F = 42.30, P < 0.05), and the four AQLQ(S) factors (Wilks’ λ = 0.68, F = 17.59, P < 0.05). The cross-sectional correlations between the 18-item AQLQ(S) and the: (1) FEV1% predicted and (2) Borg scale were low and moderately high, respectively. In conclusion, the 18-item AQLQ(S) derived from exploratory and confirmatory factor analysis appeared to have sufficient construct validity, cross-sectional validity, responsiveness, satisfactory test-retest reliability and internal consistency evidence for the Greek sample of adults with asthma. | [] | https://semanticscholar.org/paper/9e260bf1c740862af1b1177d001652ca0d9609e8 | [
"http://hypatia.teiath.gr/xmlui/bitstream/handle/11400/4135/An%2018-item%20standardized%20Asthma%20Quality%20of%20Life.pdf?sequence=3",
"http://www.axiologisis.gr/pdf/AQLQ(S).pdf"
] | [
{
"name": "Eirini Grammatopoulou",
"ids": [
"7980496"
]
},
{
"name": "Emmanouil Skordilis",
"ids": [
"2820394"
]
},
{
"name": "Dimitra Koutsouki",
"ids": [
"152500368"
]
},
{
"name": "George Baltopoulos",
"ids": [
"39716179"
]
}
] | [
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] | [
"Psychology",
"Medicine"
] | 2,007 | Quality of Life Research | Quality of Life Research | 17 | 323-332 | [
"Medline"
] | 10.1007/s11136-007-9297-y | https://doi.org/10.1007/s11136-007-9297-y | 18080214 | 2041673734 |
|
1159b0213db54fa2ac669bb32c8565842f1ada75 | What Is Our "Epistemic Responsibility"? Reflections on Social Work's Orientation in Yoga Therapy Research. | The purpose of this article is to explore how the social work discipline could provide a complementary lens through which yoga therapy can be analyzed and evaluated by engaging in knowledge-creation practices and procedures that prioritize the "epistemic responsibility" described by philosopher Lorraine Code. More specifically, by seeking to strategically include often-subjugated types of knowledge and by focusing on redistributing epistemic power to agents that typically have been excluded from epistemic participation in contemporary yoga therapy research, the social work discipline, with its strong commitment to social justice, has the potential to contribute to filling an important gap in scientific literature. We begin by presenting the relevance of the social work perspective in relation to the field of yoga therapy. We next offer a reserved critical analysis of the dominant technical knowledge base that currently informs yoga therapy practice. This analysis highlights the social parameters that may be rendered invisible or left aside when adopting a positivist epistemological lens and justifies how the conceptual apparatus of epistemic responsibility serves as a potential platform for rethinking social work's position and future contributions to the field of yoga therapy. Finally, we mobilize the concept of cultural appropriation to illustrate how striving for epistemic responsibility provides an entry point for addressing the multilevel, complex social processes embedded in yoga therapy practice and research while aiming to capture the many voices-and hence the various truths-implicated in a democratic, reflexive, and inclusive research process. | [] | https://semanticscholar.org/paper/1159b0213db54fa2ac669bb32c8565842f1ada75 | [
"https://watermark.silverchair.com/10.1776_2020-d-19-00044.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtgwggLUBgkqhkiG9w0BBwagggLFMIICwQIBADCCAroGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQME2LlXZ06b9mysrp5AgEQgIICi-JIsNBtSxYxmr2LGcOXLEKKET6SYu3qnz61vjhDQCKXJru-xqdN3uYzCn2Va4HuXJZE6NJpZapETzGzjmPrJV5itclNJ-SDFGc7-JtxJKBbg4n34qn86FRcbwYhbe36sGNKpM3V-lDJkXC-MMyL_WufX-Pozov8kHTN5Elt_QKLwLDszj41EmKAUEOx_ETzUUrqhWrzTSPvI4gutOjxTnj5pVQ4LLTSAvwJzMMGoI098W2azZs9YRkv-ApaZxWlGGzXbiJ62P4TZa0AZhCK8fT6KJZshMFKNsfSumphOaJtIJM4W8FuC9cZWzX8pXd_A_I-4Nb-x-4Y87u_3jy_JvAg-07M28Y8GUE2qlvCMvW11JG4MT-h2cjV-hmU7dffKJ6W1bae62GsEkYz8EAb-D8b2WKIzz3zmOlrmzSI1EqL3Ilkx8H533KuO3xlw-NbXobgH6sIrKVexb0g2dyIPBUY7Z1RA_gtU9w4nhJOCVXKKPIRvjegJ-U4oIXLrUuvOGSsVC6XAvvubOjyS3nEAmACiWRGbsz3eef-MklQAhjukTcXlEZ5whF8v-tuB5c0imJ1xdVkL-nQ7BhDRwsC6J9IiSX-8FLxbkE17LD8ch-UBnmZudmRKFuSwb-n0HJMIAFMaTOxr5PhzllySKZPRbDBO3HtSmCAeEv17Mfo4CyTjbno6alO4SkXLQfnxy-Axjy9tEoBuhSxTm_JeZWQ8-pD7ApGr6xPQO4hyxfzOhXGi-5v9vzLXImTIdFHWbjnMSHM-FMyf26ltmSvxmMVaul-DLSduQwsJ4gYjXlst7hOIu-l1Co7wckrgPfKykSmkJlJk8xVwHE9TQTsfl80-CwkJj05Pgrf8ig55Q"
] | [
{
"name": "Emmanuelle Larocque",
"ids": [
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]
},
{
"name": "Nicolas Moreau",
"ids": [
"34790697"
]
}
] | [] | [
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] | [
"Sociology",
"Medicine"
] | 2,020 | International journal of yoga therapy | International journal of yoga therapy | [
"Medline"
] | 10.17761/2020-D-19-00044 | https://doi.org/10.17761/2020-D-19-00044 | 32298142 | 3016313844 |
|||
920140e1d7abc54b639c741baae74085b58c63f0 | Nature of insulin binding to plastic bags. | The nature of insulin binding to plastic bags was evaluated to determine if it followed the physical laws of adsorption. To determine whether insulin is adsorbed on a liquid/air interface, the influence of foam in vials of radiolabeled insulin was evaluated. Using a bag-to-bag transfer method, the influence of regular insulin and detergent on radiotracer insulin binding was assessed. To evaluate the reversibility of the binding, bag pieces with bound radioactive insulin were washed with distilled water, detergent, and left to soak in detergent before measuring radioactivity. The radiolabeled insulin was adsorbed in the foam and then released into the bulk of the solution when the foam disappeared; hence, insulin can be entrapped in a liquid/air interface. The addition of regular insulin decreased the binding of the radiotracer insulin to the bag walls. The bound insulin could be removed by washing with water and detergent, but soaking in detergent did not remove a small residual quantity of the bound insulin, suggesting that minimal chemical binding or diffusion of the insulin into the plastic may occur. Insulin binding to plastic bags primarily follows the physical laws of adsorption. | [] | https://semanticscholar.org/paper/920140e1d7abc54b639c741baae74085b58c63f0 | [] | [
{
"name": "Z J Twardowski",
"ids": [
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]
},
{
"name": "K D Nolph",
"ids": [
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]
},
{
"name": "T J McGary",
"ids": [
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]
},
{
"name": "H L Moore",
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]
}
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] | [
"Medicine"
] | 1,983 | American journal of hospital pharmacy | American journal of hospital pharmacy | 40 4 |
579-82
| [
"Medline"
] | 10.1093/AJHP/40.4.579 | https://doi.org/10.1093/AJHP%2F40.4.579 | 6342378 | 1796247450 |
|
844cec388f126a4c7dbc21e942499bb8a9daedbb | Full-length genomic analysis of porcine G9P[23] and G9P[7] rotavirus strains isolated from pigs with diarrhea in South Korea. | Group A rotaviruses (RVAs) are agents causing severe gastroenteritis in infants and young animals. G9 RVA strains are believed to have originated from pigs. However, this genotype has emerged as the fifth major human RVA genotype worldwide. To better understand the relationship between human and porcine RVA strains, complete RVA genome data are needed. For human RVA strains, the number of complete genome data have grown exponentially. However, there is still a lack of complete genome data on porcine RVA strains. Recently, G9 RVA strains have been identified as the third most important genotype in diarrheic pigs in South Korea in combinations with P[7] and P[23]. This study is the first report on complete genome analyses of 1 G9P[7] and 3 G9P[23] porcine RVA strains, resulting in the following genotype constellation: G9-P[7]/P[23]-I5-R1-C1-M1-A8-N1-T1-E1-H1. By comparisons of these genotype constellations, it was revealed that the Korean G9P[7] and G9P[23] RVA strains possessed a typical porcine RVA backbone, similar to other known porcine RVA strains. However, detailed phylogenetic analyses revealed the presence of intra-genotype reassortments among porcine RVA strains in South Korea. Thus, our data provide genetic information of G9 RVA strains increasingly detected in both humans and pigs, and will help to establish the role of pigs as a source or reservoir for novel human RVA strains. | [] | https://semanticscholar.org/paper/844cec388f126a4c7dbc21e942499bb8a9daedbb | [] | [
{
"name": "Ha-Hyun Kim",
"ids": [
"5341938"
]
},
{
"name": "Jelle Matthijnssens",
"ids": [
"145734314"
]
},
{
"name": "Hyun-Jeong Kim",
"ids": [
"2852119"
]
},
{
"name": "Hyung-Jun Kwon",
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"4395249"
]
},
{
"name": "Jun-Gyu Park",
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"4736223"
]
},
{
"name": "Kyu-Yeol Son",
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"35324449"
]
},
{
"name": "Eun-Hye Ryu",
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]
},
{
"name": "Deok-Song Kim",
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"6754377"
]
},
{
"name": "Woo Song Lee",
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"2513574"
]
},
{
"name": "Mun-Il Kang",
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"89201367"
]
},
{
"name": "Dong-Kun Yang",
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"40226316"
]
},
{
"name": "Bang-Hun Hyun",
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"4557625"
]
},
{
"name": "Sang-Ik Park",
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]
},
{
"name": "Su-Jin Park",
"ids": [
"145816441"
]
},
{
"name": "Kyoung-Oh Cho",
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]
}
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] | [
"Biology",
"Medicine"
] | 2,012 | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases | 12 7 |
1427-35
| [
"Medline"
] | 10.1016/j.meegid.2012.04.028 | https://doi.org/10.1016/j.meegid.2012.04.028 | 22613801 | 2079336486 |
|
df9a5c9ae8e0a195f1a01f1075ca6dfa15c93402 | Trimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose. | The beta-galactosidase from an extreme thermophile, Thermus thermophilus A4 (A4-beta-Gal), is thermostable and belongs to the glycoside hydrolase family 42 (GH-42). As the first known structures of a GH-42 enzyme, we determined the crystal structures of free and galactose-bound A4-beta-Gal at 1.6A and 2.2A resolution, respectively. A4-beta-Gal forms a homotrimeric structure resembling a flowerpot. Each monomer has an active site located inside a large central tunnel. The N-terminal domain of A4-beta-Gal has a TIM barrel fold, as predicted from hydrophobic cluster analysis. The putative catalytic residues of A4-beta-Gal (Glu141 and Glu312) superimpose well with the catalytic residues of Escherichia coli beta-galactosidase. The environment around the catalytic nucleophile (Glu312) is similar to that in the case of E.coli beta-galactosidase, but the recognition mechanism for a substrate is different. Trp182 of the next subunit of the trimer constitutes a part of the active-site pocket, indicating that the trimeric structure is essential for the enzyme activity. Structural comparison with other glycoside hydrolases revealed that many features of the 4/7 superfamily are conserved in the A4-beta-Gal structure. On the basis of the results of 1H NMR spectroscopy, A4-beta-Gal was determined to be a "retaining" enzyme. Interestingly, the active site was similar with those of retaining enzymes, but the overall fold of the TIM barrel domain was very similar to that of an inverting enzyme, beta-amylase. | [] | https://semanticscholar.org/paper/df9a5c9ae8e0a195f1a01f1075ca6dfa15c93402 | [] | [
{
"name": "Masafumi Hidaka",
"ids": [
"5488476"
]
},
{
"name": "Shinya Fushinobu",
"ids": [
"5598956"
]
},
{
"name": "Naomi Ohtsu",
"ids": [
"32517695"
]
},
{
"name": "Hidemasa Motoshima",
"ids": [
"153550224"
]
},
{
"name": "Hiroshi Matsuzawa",
"ids": [
"1829268"
]
},
{
"name": "Hirofumi Shoun",
"ids": [
"3981696"
]
},
{
"name": "Takayoshi Wakagi",
"ids": [
"6764999"
]
}
] | [
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] | [
"Chemistry",
"Medicine"
] | 2,002 | Journal of molecular biology | Journal of molecular biology | 322 1 |
79-91
| [
"Medline"
] | 10.1016/S0022-2836(02)00746-5 | https://doi.org/10.1016/S0022-2836%2802%2900746-5 | 12215416 | 2015600669 |
|
88ef5a2ec3bd4c02cc1c7bad58644a33be67eb3c | Barriers to Implementing a ‘Secured by Design’ Program for the Lexington-Fayette Urban County Government | of the Martin School for assistance with this project. Opinions of those interviewed do not officially represent the view of any organization or government body. | [] | https://semanticscholar.org/paper/88ef5a2ec3bd4c02cc1c7bad58644a33be67eb3c | [
"https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1109&context=mpampp_etds&httpsredir=1&referer=",
"http://martin.uky.edu/sites/martin.uky.edu/files/Capstone_Projects/Capstones_2010/Burchett.pdf",
"https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1109&context=mpampp_etds"
] | [
{
"name": "Brent Burchett",
"ids": [
"119400149"
]
}
] | [] | [
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"6e202fba3a325f7d85634655248e2b4fbde3ad78",
"b2532ef8f2fdf5f31541c65cb8fc5ef263b1672d",
"8813772af7b3c2d293addeaf2b1ad26dfca07d6f",
"66e1912ad4584d4c96bd384c4d3bc6b10bf6162f",
"7bf9a05f632ff919987be997d9ed5b5208c8ef18",
"6234db9b3b4fdc15b1bddccde48d5b7b18db677b",
"8327a97529bbd552b3e214bf01e930bfd13f1d47",
"b82eb81a274a58d2a26ccfb100425e5d75db6ceb"
] | [
"Political Science"
] | 2,010 | [] | 1562162465 |
||||||||
51c7264e6f658705942a166d44198525f2b3ab4c | Medical image segmentation based on immune clonal optimization | Based on the clonal selection theory of Artificial Immune System, a novel optimal entropy threshold medical image segmentation method is proposed, in which, the affinity function is the optimal entropy threshold, and the medical image segmentation is considered as a optimization problem, clonal operator effectively enlarges searching range, supplies the diversity of solutions and can find the optimal threshold. This paper applies new algorithm to the challenging application: gray matter/white matter segmentation in MRI images, the algorithm is depicted in detail and the convergence is proven, the performance and computational complexity of the algorithm are described by quantitative analysis. Experiment results demonstrate the potential of the algorithm for medical image segmentation. | [] | https://semanticscholar.org/paper/51c7264e6f658705942a166d44198525f2b3ab4c | [] | [
{
"name": "Wenping Ma",
"ids": [
"38872041"
]
},
{
"name": "Licheng Jiao",
"ids": [
"144125122"
]
},
{
"name": "Ronghua Shang",
"ids": [
"145762443"
]
},
{
"name": "Fujia Zhao",
"ids": [
"9092172"
]
}
] | [
"35c8a41a795a86543bdb9a746d3534cc67e8d90b",
"b5479ea9f2e0bd64ddc2f94b4e6f224f5b9851c4",
"5b809d69d2bf86ced8c108f927ec705a51abbbef",
"3adb0ef05f3451c3945d5b65e77173a93b642677"
] | [
"af7dcf5e823f6e1eaa4aff2afa2912585ea32147",
"4d411142604ebd7496948ac0aa96d5d1f3383012",
"e970222622285b6d106f2861d49652fca729d250",
"cd8888f739a8e6e58a5aa7ea5669bc09d60ac202",
"27a2c3364d1ec35a1d1ba2a5f02489b8717531f1",
"15e05d736002fcdcde9dd5e616b4fffe5151d4fb",
"29cedf9f9edd5179aa2e78654a7b81c9da45f0d0"
] | [
"Computer Science"
] | 2,009 | 2009 IEEE International Conference on Intelligent Computing and Intelligent Systems | 2009 IEEE International Conference on Intelligent Computing and Intelligent Systems | 1 | 377-381 | [] | 10.1109/ICICISYS.2009.5357824 | https://doi.org/10.1109/ICICISYS.2009.5357824 | 1985908323 |
||
4a7f7df432506f406de9ad1f62842b35131185ec | Study of the Fusion-fission Process in the Typeset Using Revt E X 2 | Fusion-fission and fully energy-damped binary processes of the Cl+Mg reaction were investigated using particle-particle coincidence techniques at a Cl bombarding energy of Elab ≈ 8 MeV/nucleon. Inclusive data were also taken in order to determine the partial wave distribution of the fusion process. The fragment-fragment correlation data show that the majority of events arises from a binary-decay process with a relatively large multiplicity of secondary light-charged particles emitted by the two primary excited fragments in the exit channel. No evidence is observed for ternary-breakup processes, as expected from the systematics recently established for incident energies below 15 MeV/nucleon and for a large number of reactions. The binary-process results are compared with predictions of statistical-model calculations. The calculations were performed using the Extended Hauser-Feshbach method, based on the available phase space at the scission point of the compound nucleus. This new method uses temperature-dependent level densities and its predictions are in good agreement with the presented experimental data, thus consistent with the fusion-fission origin of the binary fully-damped yields. PACS numbers: 25.70.Jj, 24.60.Dr, 25.70.Gh, 25.70.-z Typeset using REVTEX 2 | [] | https://semanticscholar.org/paper/4a7f7df432506f406de9ad1f62842b35131185ec | [
"http://arxiv.org/pdf/nucl-ex/9804004v1.pdf"
] | [
{
"name": "R. Nouicer",
"ids": [
"6985202"
]
},
{
"name": "D. Mahboub",
"ids": [
"14382633"
]
},
{
"name": "B. Djerroud",
"ids": [
"89974156"
]
},
{
"name": "R. M. Freeman",
"ids": [
"2104030"
]
},
{
"name": "A. Hachem",
"ids": [
"50572765"
]
},
{
"name": "T. Matsuse",
"ids": [
"8410786"
]
}
] | [] | [] | [] | 2,008 | [] | |||||||||
14285f32ec4029f2360c414e75fdbd2a3e0c2486 | Predição de classes de solo em uma paisagem complexa no Sul do Brasil | The objective of this work was to evaluate the use of covariate selection by expert knowledge on the performance of soil class predictive models in a complex landscape, in order to identify the best predictive model for digital soil mapping in the Southern region of Brazil. A total of 164 points were sampled in the field using the conditioned Latin hypercube, considering the covariates elevation, slope, and aspect. From the digital elevation model, environmental covariates were extracted, composing three sets, made up of: 21 covariates, covariates after the exclusion of the multicollinear ones, and covariates chosen by expert knowledge. Prediction was performed with the following models: decision tree, random forest, multiple logistic regression, and support vector machine. The accuracy of the models was evaluated by the kappa index (K), general accuracy (GA), and class accuracy. The prediction models were sensitive to the disproportionate sampling of soil classes. The best predicted map achieved a GA of 71% and K of 0.59. The use of the covariate set chosen by expert knowledge improves model performance in predicting soil classes in a complex landscape, and random forest is the best model for the spatial prediction of soil classes. | [] | https://semanticscholar.org/paper/14285f32ec4029f2360c414e75fdbd2a3e0c2486 | [] | [
{
"name": "Jean Michel Moura-Bueno",
"ids": [
"1403851603"
]
},
{
"name": "Ricardo Simão Diniz Dalmolin",
"ids": [
"16220600"
]
},
{
"name": "Taciara Zborowski Horst-Heinen",
"ids": [
"1403922789"
]
},
{
"name": "Luciano Campos Cancian",
"ids": [
"83521804"
]
},
{
"name": "Ricardo Bergamo Schenato",
"ids": [
"87555992"
]
},
{
"name": "André Carnieletto Dotto",
"ids": [
"52073737"
]
},
{
"name": "C. A. Flores",
"ids": [
"1696558"
]
}
] | [] | [] | [
"Mathematics"
] | 2,019 | Pesquisa Agropecuaria Brasileira | 54 | 00420 | [] | 2991355226 |
|||||
0580207b8b5f59ab934797205783e59eb2dd356e | Effect of land management and soil texture on seasonal variations in soil microbial biomass in dry tropical agroecosystems in Tanzania | Abstract Soil microbes are an essential component of most terrestrial ecosystems; as decomposers they are responsible for regulating nutrient dynamics, and they also serve as a highly labile nutrient pool. Here, we evaluated seasonal variations in microbial biomass carbon (MBC) and nitrogen (MBN) as well as microbial activity (as qCO 2 ) for 16 months with respect to several factors relating to soil moisture and nutrients under different land management practices (plant residue application, fertilizer application) in both clayey (38% clay) and sandy (4% clay) croplands in Tanzania. We observed that MBC and MBN tended to decrease during the rainy season whereas they tended to increase and remain at high levels during the dry season in all treatment plots at both of our test sites, although soil moisture did not correlate with MBC or MBN. qCO 2 correlated with soil moisture in all treatment plots at both sites, and hence soil microbes act as decomposers mainly during the rainy season. Although the effect of seasonal variation of soil moisture on the dynamics of MBC, MBN, and qCO 2 was certainly greater than that attributable to plant residue application, fertilizer application, or soil texture, plant residue application early in the rainy season clearly increased MBC and MBN in both clayey and sandy soils. This suggests that plant residue application can help to not only counter the N loss caused by leaching but also synchronize crop N uptake and N release from soil microbes by utilizing these microbes as an ephemeral nutrient pool during the early crop growth period. We also found substantially large seasonal variations in MBC and MBN, continuously high qCO 2 , and rapid turnover of soil microbes in sandy soil compared to clayey soil. Taken together, our results indicate that soil microbes, acting as both a nutrient pool and decomposers, have a more substantial impact on tropical sandy soil than on clayey soil. | [] | https://semanticscholar.org/paper/0580207b8b5f59ab934797205783e59eb2dd356e | [] | [
{
"name": "Soh Sugihara",
"ids": [
"32897979"
]
},
{
"name": "Shinya Funakawa",
"ids": [
"48676495"
]
},
{
"name": "Method Kilasara",
"ids": [
"4801425"
]
},
{
"name": "Takashi Kosaki",
"ids": [
"32228028"
]
}
] | [
"18a9a8026c0c0c2e54085ca750e9fa2ae79171df",
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] | [
"Environmental Science"
] | 2,010 | Applied Soil Ecology | 44 | 80-88 | [] | 10.1016/J.APSOIL.2009.10.003 | https://doi.org/10.1016/J.APSOIL.2009.10.003 | 2081116185 |
|||
323914c09cd7db015377ede89d0729ae76d6f730 | Biostatistics: Statistical Analysis, Reporting, and Interpretation of Glaucoma Surgical Trials: A Brief Practice Guide | Most clinicians and clinician scientists will have had an introduction to statistics, either in medical school coursework or through their own study. However, the practice of statistics in medicine is a burgeoning discipline (witness the growth of the respected journal Statistics in Medicine since it was introduced in the early 1980s) and difficult to keep abreast of. The aim of this article will be to summarize some key concepts and techniques in biostatistics with particular reference to clinical trials, not from first principles (this is an interval level variable; that is an ordinal variable), but rather as a guide to analyses and practices commonly employed in ophthalmology journals. The format of this article is to introduce a variety of these techniques and identify some of the salient features concerning their interpretation. This summary is particularly relevant to surgical trials where treatments are compared with respect to incidence rates of treatment failure, rather than, say, medical trials that may compare average differences in intraocular pressure (IOP) lowering. The emphasis is on heuristic exposition rather than technical precision. | [] | https://semanticscholar.org/paper/323914c09cd7db015377ede89d0729ae76d6f730 | [
"http://www.jaypeebrothers.com/eJournalNEW/ShowText.aspx?ID=42&IID=6&IN=_eJournals/Journal+of+Current+Glaucoma+Practice+with+DVD.jpg&TYP=TOP&Type=PAID&isPDF=YES"
] | [
{
"name": "William J. Feuer",
"ids": [
"5435132"
]
},
{
"name": "Tanuj Dada",
"ids": [
"5551197"
]
},
{
"name": "Kuldev Singh",
"ids": [
"74746159"
]
},
{
"name": "George L. Spaeth",
"ids": [
"74706590"
]
}
] | [] | [
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] | [
"Medicine"
] | 2,007 | 1-6 | [] | 10.5005/jp-journals-10008-1048 | https://doi.org/10.5005/jp-journals-10008-1048 | 2184331843 |
|||||
3fa01e5e97df28c9671f9d6cff8957a0845960bd | Evidence of the effect of adjunct ultrasound screening in women with mammography-negative dense breasts: interval breast cancers at 1 year follow-up. | Surveillance of interval cancers (IC) provides a measure of breast screening efficacy. Increased breast density is a predictor of breast cancer risk and of the risk of IC in screening. Improving screening sensitivity in women with dense breasts, through adjunct ultrasound (US), may potentially reduce IC; however this has not been proven. We report on first-year IC in a retrospective cohort of 8865 women who had 19,728 screening examinations (2001-2006): women with non-dense (D1-D2) breasts received mammography (M) screening, and women with dense (D3-D4) breasts also received ultrasound. Data linkage with both hospital discharge records and cancer registry databases was used to identify IC. Underlying cancer rates (cancers observed within 1-year from screening) were 6.3/1000 screens in the D1-D2 group and 8.3/1000 screens in the D3-D4 group. Cancer detection rate (CDR) was 5.98/1000 in all screening examinations; in D3-D4 breasts ultrasound had an additional CDR of 4.4/1000 screens. There were 21 first-year IC, an overall interval cancer rate (ICR) of 1.07/1000 negative screens: 0.95/1000 in women < 50 years and 1.16/1000 screens in women ≥ 50 years. ICR by breast density were 1.0/1000 negative screens in D1-D2, and 1.1/1000 negative screens in D3-D4. Interval cancers were early stage (in situ or small invasive) cancers, almost all were node-negative. Screening sensitivity was 83.5% for mammography alone in D1-D2 breasts relative to 86.7% for mammography with ultrasound in D3-D4 breasts. Our study shows that including ultrasound as adjunct screening in women with D3-D4 breasts brings the IC rate to similar levels as IC in non-dense breasts--this suggests that additional cancer detection by ultrasound is likely to improve screening benefit in dense breasts, and supports the implementation of a randomised trial of adjunct ultrasound in women with increased breast tissue density. | [] | https://semanticscholar.org/paper/3fa01e5e97df28c9671f9d6cff8957a0845960bd | [
"http://ambulatoriraphael.it/wp-content/uploads/Eur_J_Cancer_1021.pdf",
"http://www.fondazionelaudatosi.it/redazione_news_doku/03/360_pdf01.pdf"
] | [
{
"name": "Vittorio Corsetti",
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]
},
{
"name": "Nehmat Houssami",
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]
},
{
"name": "Marco Ghirardi",
"ids": [
"2411991"
]
},
{
"name": "Aurora Ferrari",
"ids": [
"153332630"
]
},
{
"name": "Michela Speziani",
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"13805871"
]
},
{
"name": "Sergio Bellarosa",
"ids": [
"2257785"
]
},
{
"name": "Giuseppe Remida",
"ids": [
"46510167"
]
},
{
"name": "Cristina Gasparotti",
"ids": [
"14090486"
]
},
{
"name": "Enzo Galligioni",
"ids": [
"2049874"
]
},
{
"name": "Stefano Ciatto",
"ids": [
"5686410"
]
}
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] | [
"Medicine"
] | 2,011 | European journal of cancer | European journal of cancer | 47 7 |
1021-6
| [
"Medline"
] | 10.1016/j.ejca.2010.12.002 | https://doi.org/10.1016/j.ejca.2010.12.002 | 21211962 | 2135118182 |
|
108e5382cc0614005db2ee668356ab35b545362f | Trajectory fusion for three-dimensional volume reconstruction | We address the 3D volume reconstruction problem from depth adjacent sub-volumes acquired by a confocal laser scanning microscope (CLSM). Our goal is to align the sub-volumes by estimating a set of optimal global transformations that preserve morphological continuity of medical structures, e.g., blood vessels, in the reconstructed 3D volume. We approach the problem by learning morphological characteristics of structures of interest in each sub-volume to understand global alignment transformations. Based on the observations of morphology, sub-volumes are aligned by connecting the morphological features at the sub-volume boundaries by minimizing morphological discontinuity. To minimize the discontinuity, we introduce three morphological discontinuity metrics: discontinuity magnitude at sub-volume boundary points, and overall and junction discontinuity residuals after polynomial curve fitting to multiple aligned sub-volumes. The proposed techniques have been applied to the problem of aligning CLSM sub-volumes acquired from four consecutive physical cross sections. Our experimental results demonstrated significant improvements of morphological smoothness of medical structures in comparison with the results obtained by feature matching at the sub-volume boundaries. The experimental results were evaluated by visual inspection and by quantifying morphological discontinuity metrics. | [] | https://semanticscholar.org/paper/108e5382cc0614005db2ee668356ab35b545362f | [
"https://www.wikidata.org/entity/Q33426309",
"http://isda.ncsa.uiuc.edu/peter/publications/journals/2007/lee07.pdf"
] | [
{
"name": "Sang-Chul Lee",
"ids": [
"1838575"
]
},
{
"name": "Peter Bajcsy",
"ids": [
"2466831"
]
}
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] | [
"Computer Science",
"Medicine"
] | 2,008 | Comput. Vis. Image Underst. | Computer vision and image understanding : CVIU | 110 1 |
19-31
| [
"Medline",
"DBLP"
] | 10.1016/j.cviu.2007.02.005 | https://doi.org/10.1016/j.cviu.2007.02.005 | 19343076 | 2110974500 |
|
284c130709b375aeb437390f20ccb7f21543638c | Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists. | Recently, various non-peptide corticotropin-releasing factor1 (CRF1) receptor antagonists have been reported. Structure-affinity relationships (SARs) of non-peptide CRF antagonists suggest that such antagonists can be constructed of three units: a hydrophobic unit (Up-Area), a proton accepting unit (Central-Area), and an aromatic unit (Down-Area). Our interest focused on the Up-Area in deriving the novel methylidenepiperidine derivatives 8-10 and 4-aryl-1,2,3,6-tetrahydropyridine derivatives 11-13 as non-peptide CRF1 receptor antagonists. Compounds 8a and 11a had moderate affinity for CRF1 receptor, but compounds 9, 10, 12 and 13 did not exhibit CRF1 receptor affinity. Modification of derivatives 11 afforded compounds 11i (CRA1001) and 11x (CRA1000), which had high affinity and selectivity for CRF1 receptors with potent anxiolytic-like and antidepressant-like properties in some experimental animal models. These findings suggest that the hydrophonic unit (Up-Area) may be useful for design of CRF1 antagonists. We report here the design, synthesis and SARs of the derivatives 8 and 11 and isosteres 9, 10, 12 and 13. | [] | https://semanticscholar.org/paper/284c130709b375aeb437390f20ccb7f21543638c | [] | [
{
"name": "A Nakazato",
"ids": [
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]
},
{
"name": "T Kumagai",
"ids": [
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]
},
{
"name": "T Okubo",
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]
},
{
"name": "H Tanaka",
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]
},
{
"name": "S Chaki",
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]
},
{
"name": "S Okuyama",
"ids": [
"1705800"
]
},
{
"name": "K Tomisawa",
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]
}
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] | [
"Chemistry",
"Medicine"
] | 2,000 | Bioorganic & medicinal chemistry | Bioorganic & medicinal chemistry | 8 5 |
1183-93
| [
"Medline"
] | 10.1016/S0968-0896(00)00045-6 | https://doi.org/10.1016/S0968-0896%2800%2900045-6 | 10882028 | 1988371688 |
|
21977371158b896c1ec7c67612960d43b6b28cc5 | MICRON WAVELENGTH SCANNING POLARIZATION LIDAR | Since the last ILRC, NCAR’s Raman-shifted Eye-safe Aerosol Lidar (REAL) has been upgraded to feature backscatter polarization sensitivity and it has been deployed in several field experiments. This paper describes the hardware improvements implemented to enable the polarization capability and observations of various types of aerosol plumes released on a military test range. The REAL was also deployed as part of the NSF sponsored T-REX experiment in March of 2006 in order to visualize the atmospheric flow in the Owens Valley of California. Examples of data from that experiment will be shown. Lastly, we will briefly describe a second generation REAL (“v2”) that was created by ITT Industries for continuous and unattended operation. | [] | https://semanticscholar.org/paper/21977371158b896c1ec7c67612960d43b6b28cc5 | [
"https://laser-sensing.jp/ilrc23_CD1a2b3c/ILRC23/2P-25.pdf"
] | [
{
"name": "Shane D. Mayor",
"ids": [
"31891354"
]
},
{
"name": "Scott M. Spuler",
"ids": [
"34582097"
]
},
{
"name": "Bruce M. Morley",
"ids": [
"47576795"
]
},
{
"name": "Eric Loew",
"ids": [
"65991797"
]
},
{
"name": "Tammy M. Weckwerth",
"ids": [
"30863901"
]
},
{
"name": "Stephan De Wekker",
"ids": [
"4165902"
]
},
{
"name": "Daniel J. Kirshbaum",
"ids": [
"114535600"
]
}
] | [] | [
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] | [] | -1 | [] | |||||||||
e93f0a500c63cf5c2ff8e28cf5f68ea338e31b8b | Heat transfer in transitional and turbulent boundary layers with system rotation | Abstract The present paper reports on the influence of system rotation on the heat transfer characteristics of transitional and turbulent zero-pressure gradient boundary layers. A test plate is installed in a wind tunnel, which is rotatable around the axis parallel to the plate leading edge with constant speed of rotation. Local heat transfer coefficient during rotation is determined by employing a thermochromic liquid crystal. Effects of the Coriolis force and the centrifugal buoyancy force have been examined by comparing the heat transfer coefficient with different free-stream velocities, rotational speeds and wall temperatures. It has been revealed that the Coriolis force has significant effect on transitional heat transfer, while its effect on turbulent heat transfer is moderate. The centrifugal buoyancy exhibits additional effects if the thermal loading is high. | [] | https://semanticscholar.org/paper/e93f0a500c63cf5c2ff8e28cf5f68ea338e31b8b | [] | [
{
"name": "D. Yamawaki",
"ids": [
"93847280"
]
},
{
"name": "Shinnosuke Obi",
"ids": [
"30527975"
]
},
{
"name": "Shigeaki Masuda",
"ids": [
"10040416"
]
}
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] | [
"Physics"
] | 2,002 | International Journal of Heat and Fluid Flow | 23 | 186-193 | [] | 10.1016/S0142-727X(01)00148-5 | https://doi.org/10.1016/S0142-727X%2801%2900148-5 | 2015909422 |
|||
5fd5af0d0be675ebd7401c4191fd87fdd9d70712 | Development of a Novel Computer-Aided Diagnosis System for Automatic Discrimination of Malignant From Benign Solitary Pulmonary Nodules on Thin-Section Dynamic Computed Tomography | Objectives: As an application of the computer-aided diagnosis of solitary pulmonary nodules (SPNs), 3-dimensional contrast-enhanced (CE) dynamic helical computed tomography (HCT) was performed to evaluate temporal changes in the internal structure of nodules to differentiate between benign nodules (BNs) and malignant nodules (MNs). Methods: There were 62 SPNs (35 MNs and 27 BNs) included in this study. Scanning (2-mm collimation) was performed before and 2 and 4 minutes after CE dynamic HCT. The CT data were sent to a computer, and the pixels inside the nodule were characterized in terms of 3 parameters (attenuation, shape index, and curvedness value). Results: Based on the CT data at 4 (MN: 1.81-27.1, BN: −42.8 to −3.29) minutes after CE-dynamic HCT, a score of 0 or higher can be assumed to indicate an MN. Conclusions: Three-dimensional computer-aided diagnosis of the internal structure of SPNs using CE dynamic HCT was found to be effective for differentiating between BNs and MNs. | [] | https://semanticscholar.org/paper/5fd5af0d0be675ebd7401c4191fd87fdd9d70712 | [] | [
{
"name": "Kiyoshi Mori",
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"48299531"
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{
"name": "Noboru Niki",
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{
"name": "Teturo Kondo",
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},
{
"name": "Yukari Kamiyama",
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]
},
{
"name": "Teturo Kodama",
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},
{
"name": "Yoshiki Kawada",
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"12893327"
]
},
{
"name": "Noriyuki Moriyama",
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]
}
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] | [
"Medicine"
] | 2,005 | Journal of computer assisted tomography | Journal of Computer Assisted Tomography | 29 | 215-222 | [
"Medline"
] | 10.1097/01.rct.0000155668.28514.01 | https://doi.org/10.1097/01.rct.0000155668.28514.01 | 15772540 | 2051450557 |
|
11de1eb90d635f240c82044067f466fa16e43b6f | Pharmacognostic and Physico-chemical Standardization of Monotheca buxifolia (Falc.) A. DC. | Monotheca buxifolia is an ethno-medicinally important plant of Pak-Afghan regions. The pharmacognostic standards of fruit, leaf, seed, barks of stem and root were set in present study. Microscopy revealed characteristic distinguishable powder drug fragments. Each part showed certain unique florescence behaviour with various reagents under light of various wavelengths. It has a broad spectrum phytochemical profile including amino acids and proteins, fats (fixed oils), sugars (both non reducing and reducing), alkaloids, flavonoids, glycosides, tannins, triterpenoids, phenolics, saponins, phytosterols and anthocyanins. The fruit had 15.5% moisture contents seed and leaf had 8.5% each and stem and root bark had 9.5% each. The values of total ash were 7.0, 6.0, 4.5, 8.25 and 11.75%; values of water soluble ash were 4.9, 3.5, 0.5, 4.2 and 6.75%, while the values of acid insoluble ash 1.5, 1.75, 4.0, 3.75 and 4.25% in fruit pulp, leaf, stem bark, root bark and seeds, respectively. The fixed oil yield of M. buxifolia was measured to be 8.33, 10.62 and 0.56% in fruit pulp, seeds and leaves, respectively. Palmitic acid, Oleic acid, Linolenic acid, Stearic acid and Myristic acid were the most frequently found fatty acids in each part. The plant is a rich source of phosphorus, nitrogen and potassium. The plant contained safe amounts of tested trace elements as directed by WHO except for cobalt in root bark (10.7±0.01) and lead in stem bark (22.48±0.33). | [] | https://semanticscholar.org/paper/11de1eb90d635f240c82044067f466fa16e43b6f | [] | [
{
"name": "Maryam Ehsan",
"ids": [
"89423835"
]
},
{
"name": "Muhammad Ibrar",
"ids": [
"51324561"
]
},
{
"name": "Fazal Hadi",
"ids": [
"1828836990"
]
},
{
"name": "Barkatullah Khan",
"ids": [
"1752906668"
]
}
] | [] | [] | [
"Chemistry"
] | 2,020 | 63 | 77-85 | [] | 3081516946 |
||||||
6d8341a619f2567a025f712227632ac3a529e861 | Numerical Analysis of an Offshore Pratol Vessel to Work in the GoM Using the Finite Element Method | At new ship's design stages, an important requirement is to grant the structure safety during ship's operation. In this scenario, it is relevant to make a dynamic analysis to identify possible resonance conditions between the structure and the main excitation sources. This work is evaluating the dynamic analysis and the structural strength according to the recommendations from the classification society DNV GL for the Oceanic Patrol type OPV. The calculation of the RAO's was developed using the Motion Maxsurf software to evaluate it. The structure of a ship is analysed with different loading conditions. The vessel is considered as a beam, supported, on a wave of length equal to the length of the vessel whose ridge is in the hull girder, or on the same wave, but with the breast in the mainframe and it is crests forward and Stern. The structural strength of the main frame of a vessel by the Finite Element Method using the GeniE DNV GL software. The results are in good agreement for this patrol to navigate on the Gulf of Mexico. | [] | https://semanticscholar.org/paper/6d8341a619f2567a025f712227632ac3a529e861 | [] | [
{
"name": "Carlos A. Ruiz",
"ids": [
"145749967"
]
},
{
"name": "Yosseline Vargas Meza",
"ids": [
"1452353895"
]
},
{
"name": "Mariana Silva-Ortega",
"ids": [
"1450800125"
]
},
{
"name": "Mariano Azzur Hernández",
"ids": [
"1452310432"
]
},
{
"name": "José Hernández",
"ids": [
"18072297"
]
}
] | [] | [
"59ccca497472679133ff194ce9ab2943745712aa"
] | [
"Geology"
] | 2,019 | 2019 IEEE International Conference on Engineering Veracruz (ICEV) | 2019 IEEE International Conference on Engineering Veracruz (ICEV) | I | 1-7 | [] | 10.1109/ICEV.2019.8920513 | https://doi.org/10.1109/ICEV.2019.8920513 | 2991832727 |
||
553e799647ed9e9941275d95154b3c055b6943fd | [Address delivered by John E. Fogarty over radio station WJAR in Providence, Rhode Island] | As the U.S. entered the Korean conflict, Fogarty argued that funding for medical research should be increased, because disease
takes a huge economic toll, just as war does. | [] | https://semanticscholar.org/paper/553e799647ed9e9941275d95154b3c055b6943fd | [] | [
{
"name": "John E. Fogarty",
"ids": [
"52611790"
]
}
] | [] | [] | [
"Medicine"
] | 1,950 | [] | 2747441590 |
||||||||
dd47e92f8f71bf0eb854aead43e58fe57c33b2dd | HEALTH CARE POST‐KATRINA: RECOMMENDATIONS FOR MEDICATION DONATIONS TO POSTDISASTER CLINICS.: 318 | disorder (95% CI 1.4, 2.0) and 1.4 times more likely to have an anxiety disorder (95% CI 1.2, 1.7). Children 10 to 14 years of age on atypical antipsychotics are 2.8 times more likely to have a diagnosis of disruptive disorder than children 15 to 18 years old (95% CI 2.3, 3.4), whereas children 15 to 18 years of age were 1.7 times more likely to have a diagnosis of a mood disorder than children 10 to 14 years old (95% CI 1.4, 2.1). A total of 173 children (7.5%) had no psychiatric diagnosis coded during the study period. Conclusions: The rate of atypical antipsychotic use in privately insured youth is similar to that of a Medicaid population (11.6 vs 13 per 1,000). Although disruptive behavior disorders are the primary diagnoses in youth on atypical antipsychotics, the majority of children prescribed an atypical antipsychotic have multiple psychiatric diagnoses. Studies are needed to assess the risk-benefit ratio and long-term safety and efficacy in these patients. | [] | https://semanticscholar.org/paper/dd47e92f8f71bf0eb854aead43e58fe57c33b2dd | [] | [
{
"name": "E. Howe",
"ids": [
"82929782"
]
},
{
"name": "D. Victor",
"ids": [
"152821200"
]
},
{
"name": "E. G. Price",
"ids": [
"32294883"
]
}
] | [] | [] | [] | 2,007 | Journal of Investigative Medicine | 55 | S300 | [] | ||||||
be6a00674c9835df749a1ba2c00cbd78f2908440 | A new method for measuring excess carrier lifetime in bulk silicon: Photoexcited muon spin spectroscopy | We have measured the optically injected excess carrier lifetime in silicon using photoexcited muon spin spectroscopy. Positive muons implanted deep in a wafer can interact with the excess carriers and directly probe the bulk carrier lifetime whilst minimizing the effect from surface recombination. The method is based on the relaxation rate of muon spin asymmetry, which depends on the excess carrier concentration. The underlying microscopic mechanism has been understood by simulating the fourstate muonium model in Si under illumination. We apply the technique to different injection levels and temperatures, and demonstrate its ability for injectionand temperature-dependent lifetime spectroscopy. | [] | https://semanticscholar.org/paper/be6a00674c9835df749a1ba2c00cbd78f2908440 | [
"https://qmro.qmul.ac.uk/xmlui/bitstream/handle/123456789/28976/Drew%20A%20new%20method%202017%20Accepted.pdf?isAllowed=y&sequence=1",
"https://arxiv.org/pdf/1702.06846v2.pdf"
] | [
{
"name": "K. Yokoyama",
"ids": [
"153888279"
]
},
{
"name": "J. S. Lord",
"ids": [
"145169122"
]
},
{
"name": "J. Miao",
"ids": [
"103118787"
]
},
{
"name": "P. Murahari",
"ids": [
"2488925"
]
},
{
"name": "A. J. Drew",
"ids": [
"3018760"
]
}
] | [] | [
"436cd5950719240811f3f1a745ea6b29c31a4d98",
"8e86507c92f98c4aa2e5f213d431776c10c6e1b0",
"75aa1f1a04b5f2bb6bf9afb662711121edde9eda",
"032a594d5edf02fd92b14b0fb3e853ee8067871c",
"1f4b85e089f28682f969cf796cd3e72151eb719a",
"725cd02f9ab4e5e4f7db6ef0d2ff5b13819a6fc1"
] | [
"Physics"
] | 2,017 | [] | 10.1103/PhysRevLett.119.226601 | https://doi.org/10.1103/PhysRevLett.119.226601 | |||||||
b9ba61a9f7f0013c3f4a91ad38eb9f284b7db0eb | [The cardiovascular system at long periods after radiotherapy of lymphogranulomatosis]. | The cardiovascular system was analysed in 157 patients with Hodgkin's disease in a prolonged remission after radiation therapy including irradiation of the mediastinum. The revealed myocardial changes were equally often noted in different irradiation volumes of the heart within the range of 31 to 45 Gy. The number of changes was growing with time. Functional disorders of the pulmonary, hepatic and capillary vessels were also revealed. | [] | https://semanticscholar.org/paper/b9ba61a9f7f0013c3f4a91ad38eb9f284b7db0eb | [] | [
{
"name": "I P Shishkin",
"ids": [
"3242860"
]
},
{
"name": "N A Metliaeva",
"ids": [
"49684826"
]
},
{
"name": "A V Barabanova",
"ids": [
"4671003"
]
}
] | [] | [] | [
"Medicine"
] | 1,984 | Meditsinskaia radiologiia | Meditsinskaia radiologiia | 29 9 |
46-50
| [
"Medline"
] | 6482706 | ||||
b9b5b36109c837f3fe435cccae36cfc454442a3c | Awareness and practice regarding cervical cancer screening among women visiting a tertiary hospital of Kathmandu | Background: Cervical cancer is the leading female cancer in Nepal. Fortunately, it is preventable by detecting precancerous lesions and by various screening tools for early invasive cancers. Screening can be possible if women are aware of the problem. Despite the existence of effective screening using Pap smear, the uptake of screening is poor. Objectives: The objective of this study was to assess the awareness and practice regarding cervical cancer screening among women visiting tertiary hospital. Methodology: A descriptive cross – sectional study was conducted to assess the awareness and practice regarding cervical cancer screening among women attending in gynaecological outpatient department of Kathmandu Medical College Teaching Hospital. A total of one hundred and fifty two women were selected purposively for the study. Structured questionnaire was designed and data collection was done through face to face interview technique during the period of September to November 2018. The collected data were analyzed by using Statistical Package for Social Science version 20. Results: Among 152 respondents, majority of the respondents (59.2%) were aware that multiple sexual partners is one of the risk factors of cervical cancer. 38.8% were aware that cervical cancer can be prevented by regular cervical screening. Majority of the respondents: 152 (44.7%) had given correct response regarding meaning of cervical cancer screening and 42.8% were aware of Pap smear test for cervical screening. Only 31.6% had performed cervical cancer screening at least once. Overall mean percentage knowledge was 3.08 with SD 0.96.There was weak correlation between knowledge and practice. Conclusion: This study concluded that majority of respondents had inadequate knowledge and practice regarding cervical cancer screening. Thus, cervical cancer screening health camps and awareness program should be conducted at community to national level for women, to increase the level of knowledge and practice regarding cervical cancer screening. | [] | https://semanticscholar.org/paper/b9b5b36109c837f3fe435cccae36cfc454442a3c | [
"https://www.nepjol.info/index.php/JKMC/article/download/28169/23215"
] | [
{
"name": "Puspa Parajuli",
"ids": [
"52611402"
]
},
{
"name": "Narayani Paudel",
"ids": [
"52415519"
]
},
{
"name": "Sunita Dahal",
"ids": [
"1580281228"
]
}
] | [] | [
"ce5f8afeee1692b8326610b003374bb41dc60ce2",
"daf084d4103c188dfb666ab76c5575719cb8ce3f",
"1a0cdbcb74ebfbab76ad7a400cc8639cd96f4ce9",
"360118e75ae9b438795360c1df69abfe16574667",
"ee452c68b083569055ff24da516dcd52379080ba",
"c25d5ccce1bb56b914da2ff18ba928845dec70b1",
"9ddf155f3a032eb7aa9f9a692f89abe758cebc36",
"1079694b1d5a8b69dbdf93e4990762e69cdee1b1",
"34c9ecb0c7f77c0e0537163b51fbf66fbfcc7265",
"ca46d763f1be9cc293c00f9bcdebb42a77fb7c9e",
"ff0ddf65765888f65a12c2072cded0c3cc508d5d"
] | [
"Medicine"
] | 2,019 | Journal of Kathmandu Medical College | 8 | 81-86 | [] | 10.3126/JKMC.V8I2.28169 | https://doi.org/10.3126/JKMC.V8I2.28169 | 3012009954 |
|||
3ac47f6cdd6aa123e085e1cc8692cdc70fa6b8cc | Angio-oedema associated with colistin. | A 50-year-old woman known to have type 1 diabetes mellitus presented with a rare case of angio-oedema associated with colistin use. The angio-oedema was temporally associated with the use and discontinuation of colistin with the reasonable exclusion of important differential diagnoses. Pseudoallergy may be a probable underlying mechanism. However, we cannot exclude the possibility of hereditary angio-oedema type 2 or 3, or that her concomitant medications (particularly enalapril) and her renal impairment contributed to the risk and severity of her angio-oedema. | [] | https://semanticscholar.org/paper/3ac47f6cdd6aa123e085e1cc8692cdc70fa6b8cc | [
"https://scholar.sun.ac.za/bitstream/handle/10019.1/102337/abulfathi_angio-oedema_2016.pdf?isAllowed=y&sequence=1",
"https://www.ajol.info/index.php/samj/article/download/146664/136190",
"http://www.scielo.org.za/pdf/samj/v106n10/22.pdf"
] | [
{
"name": "A A Abulfathi",
"ids": [
"7932390"
]
},
{
"name": "T Greyling",
"ids": [
"11743034"
]
},
{
"name": "M Makiwane",
"ids": [
"35487058"
]
},
{
"name": "M Esser",
"ids": [
"47672141"
]
},
{
"name": "E Decloedt",
"ids": [
"5426727"
]
}
] | [
"0bcdf3aea3cc0b59d5dde496acf72ccf087616c1"
] | [
"0e718751d68c2d7beacd25b1169eae1c7d966b63",
"edf0e2237b4cde6d983a3d2c447fcbe8dc478964",
"69b81105ff8d02f49abe045084c9f48542ef695c",
"aa0971025aa2d9b1f8ed1896d5989805715bbd2c",
"bf3e199d8dbc8dcf5f6aac8f3dfd1994d99bcadd",
"64fe2e01fe84cc3e7e76f4b734a33f2deaa16763",
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"2390b17078ce80eca239d4f9aed61ae823c08179",
"038786a814318aceaa849fc6600b1908269d0d2b"
] | [
"Medicine"
] | 2,016 | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | 106 10 |
990-991
| [
"Medline"
] | 10.7196/SAMJ.2016.v106i10.10835 | https://doi.org/10.7196/SAMJ.2016.v106i10.10835 | 27725018 | 2528709608 |
|
8bd6e48bb24612d46c647b52277b876340d1da58 | Dating trials of wooden historic artefacts through FT-IR spectroscopy | Abstract This paper constitutes an attempt at using FT-IR spectroscopy for the dating of historical and artistic artefacts made of poplar wood. It was decided to do the tests only on poplar (Populus spp.) to reduce a part of the typical wood variability, while poplar was chosen because it is widely present in Italian heritage, such as panel paintings, statues and furniture, and these objects cannot be dated by dendrochronology; also because 14C methodology has major limitations. Poplar artefacts from the fourteenth to the nineteenth century were selected, dated by means of documents, by attributions, or stylistically. In addition, recent poplar samples were selected as a reference. Wood flour were taken from the selected samples, discarding the surface layers that could have been influenced by oxidation phenomena. Before taking measurements with FT-IR, the wood meal was dried and the chemical extractives were removed. The results show the presence of a time-related trend, but the time factor is certainly not the only one that causes the variations within the spectra. After a discussion, it is therefore considered that the results do not allow at the current state to definitely produce a reliable reference for dating poplar wood artefacts through this methodology. | [] | https://semanticscholar.org/paper/8bd6e48bb24612d46c647b52277b876340d1da58 | [] | [
{
"name": "Nicola Macchioni",
"ids": [
"14603082"
]
},
{
"name": "Benedetto Pizzo",
"ids": [
"7260776"
]
},
{
"name": "Mauro Bernabei",
"ids": [
"14530816"
]
},
{
"name": "Giovanna Visintin",
"ids": [
"1582385060"
]
}
] | [] | [
"725dd023379920516e30466c3d39cf8e2792569f",
"2c2e6e8144399aaa316ac734b9994760020ecd27",
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"f4811c52b350cd7a16fbd8080a5a4b383ef1147f",
"b18ab6e16b6d7d4d1c6b9c3b2cba35a40f01c6f2",
"a8d9a4b25298f4357e85423e9de796ee2c20c5a8",
"7e16457ffb80b9c4a1e1d54173848932edb99226",
"8df050b61ed7c38daf04678df600f64082c0a7c2",
"6678ebf88f1016b5abb3865b87bd8a4e0c3a410f",
"4e56e250575136d6505c84cf836aa2b5559c7cfc",
"b54d518cda70199daf03674e27671aafcbcec657",
"b9117457d5e7971de6f9261ebd7264e61960c4a8"
] | [
"Art"
] | 2,020 | Journal of Cultural Heritage | 43 | 303-310 | [] | 10.1016/j.culher.2019.10.011 | https://doi.org/10.1016/j.culher.2019.10.011 | 2991676674 |
|||
ca9ac06f5f05326a173f2a82c14ccf9d16877719 | Morphants: A New Systematic Vertebrate Functional Genomics Approach | The vertebrate genome contains a predicted 50 000–100 000 genes, many of unknown function. The recent development of morpholino‐based gene knock‐down technology in zebrafish has opened the door to the genome‐wide assignment of function based on sequence in a model vertebrate. This review describes technical aspects of morpholino use for functional genomics applications, including the potential for multigene targeting and known methodological limitations. The result of successful gene inactivation by this agent is proposed to yield embryos with a ‘morphant’ phenotypic designation. The establishment of a morphant database opens the door to true functional genomics using the vertebrate, Danio rerio. Copyright © 2000 John Wiley & Sons, Ltd. | [] | https://semanticscholar.org/paper/ca9ac06f5f05326a173f2a82c14ccf9d16877719 | [
"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/63/ed/Yeast_2000_17(4)_302-306.tar.gz",
"http://ftp.ncbi.nlm.nih.gov/pub/pmc/63/ed/CFG-01-302.PMC2448384.pdf"
] | [
{
"name": "Stephen C. Ekker",
"ids": [
"2043890"
]
}
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] | [
"Medicine",
"Biology"
] | 2,000 | Yeast | Yeast (Chichester, England) | 17 | 302 - 306 | [
"Medline"
] | 10.1002/1097-0061(200012)17:4<302::AID-YEA53>3.0.CO;2-# | https://doi.org/10.1002/1097-0061%28200012%2917%3A4%3C302%3A%3AAID-YEA53%3E3.0.CO%3B2-%23 | 11119307 | 2020872373 |
|
8d96d487f5052e9dc8368e4a37e5d20a3beb2430 | Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice | Human interleukin-15 (hIL15) has anti-tumor activities, but it is not convenient for tumor treatment because of its short half-life. A gene therapy for mouse lung cancer using an adenovirus vector expressing IL15 has been reported. However, adenovirus vector-mediated gene therapy can provoke cellular toxicity and inflammatory reactions. The recombinant adenovirus-associated vector 2 (rAAV2) is safer due to minimal cellular toxicity and immune response. In order to demonstrate that gene therapy can be used safely and successfully for human cancer treatment, the rAAV2 expressing hIL15 gene (rAAV2-hIL15) is applied for human cervical cancer, HeLa cell, in this study. This study successfully demonstrates that rAAV2-hIL15 can express IL15 with bioactivities in vitro and in vivo. In conclusion, our studies show that human cervical cancers are inhibited on animal model with rAAV2-hIL15 treatment and provide a safer and important reference for human cancer gene therapy. | [] | https://semanticscholar.org/paper/8d96d487f5052e9dc8368e4a37e5d20a3beb2430 | [
"http://www.researchgate.net/profile/Horng-Jyh_Harn/publication/24408703_Immunotherapy_rAAV2_expressing_interleukin-15_inhibits_HeLa_cell_tumor_growth_in_mice/links/09e4150874116e04ed000000.pdf"
] | [
{
"name": "Giou-Teng Yiang",
"ids": [
"5003783"
]
},
{
"name": "Horng-Jyh Harn",
"ids": [
"3513702"
]
},
{
"name": "Yung-Luen Yu",
"ids": [
"3720512"
]
},
{
"name": "Sheng-Chuan Hu",
"ids": [
"116709349"
]
},
{
"name": "Yu-Ting Hung",
"ids": [
"48998984"
]
},
{
"name": "Chia-Jung Hsieh",
"ids": [
"46345858"
]
},
{
"name": "Shinn-Zong Lin",
"ids": [
"5375545"
]
},
{
"name": "Chyou-Wei Wei",
"ids": [
"4938980"
]
}
] | [
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] | [
"Biology",
"Medicine"
] | 2,008 | Journal of Biomedical Science | Journal of Biomedical Science | 16 | 47 - 47 | [
"Medline"
] | 10.1186/1423-0127-16-47 | https://doi.org/10.1186/1423-0127-16-47 | 19422685 | 1989305622 |
|
5d76490f7560ad8958b952660440ca1e7ac0540a | Electrification of residential space heating considering coincidental weather events and building thermal inertia: A system-wide planning analysis | The increasing deployment of variable renewables and parallel residential space heat electrification using heat pumps poses two significant challenges for electricity systems: First, coincidence of certain weather events can stress the power system due to the increasing weather-dependence on both supply and demand side; Secondly, increased net load demand requires large capacity expansion unless heat and electricity can be partially decoupled. This paper proposes a planning methodology to explore these challenges by integrating a ‘Resistance-Capacitance’ representation of building thermodynamics into an integrated planning model. This enables analysis of coincidental weather effects which drive system adequacy and of the potential to utilise building thermal inertia to pre-heat the building and effectively store electricity in the form of heat according to system conditions. The model was tested with a case study for the Irish energy system in 2030. It was found that different weather patterns considerably influence investment and planning choices. Also, coincidental effects of different weather variables – in this case, low temperatures and low wind speed - define the most critical situations in terms of adequacy. By utilising building thermal inertia, total system costs of residential heat electrification can be reduced to the level of the benchmark technology, gas boilers. | [] | https://semanticscholar.org/paper/5d76490f7560ad8958b952660440ca1e7ac0540a | [
"http://isiarticles.com/bundles/Article/pre/pdf/150036.pdf",
"https://isiarticles.com/bundles/Article/pre/pdf/150036.pdf"
] | [
{
"name": "Steve Heinen",
"ids": [
"30851940"
]
},
{
"name": "William J.N. Turner",
"ids": [
"48713541"
]
},
{
"name": "Lucy Cradden",
"ids": [
"30750335"
]
},
{
"name": "Frank McDermott",
"ids": [
"31384801"
]
},
{
"name": "Mark O'Malley",
"ids": [
"1400612963"
]
}
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] | [
"Engineering"
] | 2,017 | Energy | 127 | 136-154 | [] | 10.1016/J.ENERGY.2017.03.102 | https://doi.org/10.1016/J.ENERGY.2017.03.102 | 2597567098 |
|||
8a5715832616cc128fb20b9982ea67707dabb32d | A Class of Markov Chain Models for Average Run Length Computations for Autocorrelated Processes | The average run length (ARL) of conventional control charts is typically computed assuming temporal independence. However, this assumption is frequently violated in practical applications. Alternative ARL computations have often been conducted via time consuming and yet not necessarily very accurate simulations. In this article, we develop a class of Markov chain models for evaluating the run length performance of traditional control charts for autocorrelated processes. We show extensions from the univariate AR(1) model to the general multivariate VARMA(p, q) time series. The results of the proposed method are highly comparable to those of simulations and with significantly less computational overhead. | [] | https://semanticscholar.org/paper/8a5715832616cc128fb20b9982ea67707dabb32d | [
"https://doi.org/10.1080/03610918.2012.667474"
] | [
{
"name": "Xuan Huang",
"ids": [
"46422720"
]
},
{
"name": "Nuo Xu",
"ids": [
"144556892"
]
},
{
"name": "Søren Bisgaard",
"ids": [
"2029372"
]
}
] | [
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] | [
"Mathematics",
"Computer Science"
] | 2,013 | Commun. Stat. Simul. Comput. | Communications in Statistics - Simulation and Computation | 42 | 1495 - 1513 | [
"DBLP"
] | 10.1080/03610918.2012.667474 | https://doi.org/10.1080/03610918.2012.667474 | 2017618089 |
||
38f9e0aa00ce09b2b0486da7d57fbeba7c64da1e | Atmospheric Variability Driven by Radiative Cloud Feedback in Brown Dwarfs and Directly Imaged Extrasolar Giant Planets | Growing observational evidence has suggested active meteorology in the atmospheres of brown dwarfs (BDs) and directly imaged extrasolar giant planets (EGPs). In particular, a number of surveys have shown that near-infrared brightness variability is common among L and T dwarfs. Despite the likelihood from previous studies that atmospheric dynamics is the major cause of the variability, the detailed mechanism of the variability remains elusive, and we need to seek a natural, self-consistent mechanism. Clouds are important in shaping the thermal structure and spectral properties of these atmospheres via their opacity, and we expect the same for inducing atmospheric variability. In this work, using a time-dependent one-dimensional model that incorporates a self-consistent coupling between the thermal structure, convective mixing, cloud radiative heating/cooling, and condensation/evaporation of clouds, we show that radiative cloud feedback can drive spontaneous atmospheric variability in both temperature and cloud structure under conditions appropriate for BDs and directly imaged EGPs. The typical periods of variability are 1 to tens of hr, with a typical amplitude of the variability up to hundreds of K in effective temperature. The existence of variability is robust over a wide range of parameter space, but the detailed evolution of the variability is sensitive to model parameters. Our novel, self-consistent mechanism has important implications for the observed flux variability of BDs and directly imaged EGPs, especially for objects whose variability evolves on short timescales. It is also a promising mechanism for cloud breaking, which has been proposed to explain the L/T transition of BDs. | [] | https://semanticscholar.org/paper/38f9e0aa00ce09b2b0486da7d57fbeba7c64da1e | [
"https://www.lpl.arizona.edu/~showman/publications/tan-showman-2018-submitted.pdf",
"https://arxiv.org/pdf/1809.06467v2.pdf",
"http://www.lpl.arizona.edu/~showman/publications/tan-showman-2019.pdf"
] | [
{
"name": "Xianyu Tan",
"ids": [
"49902174"
]
},
{
"name": "Adam P. Showman",
"ids": [
"143987214"
]
}
] | [
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] | [
"Physics"
] | 2,018 | The Astrophysical Journal | 874 | 111 | [] | 10.3847/1538-4357/ab0c07 | https://doi.org/10.3847/1538-4357%2Fab0c07 | 2951207101 |
|||
26c5a7b950919ac32178f74d4f28d6e6b5b44cb8 | Geographic distribution of stroke mortality in the United States | I used data from the National Center for Health Statistics to map the geographic distribution of age-adjusted, race- and gender-specific stroke mortality rates in the United States from 1939-1941 to 1979-1981. Over this interval, stroke mortality rates declined dramatically with convergence of age-adjusted, state-specific stroke rates both within and between the various race-gender groups. For each race-gender group, high age-adjusted stroke mortality rates were significantly clustered in the southeastern United States, particularly in the South Atlantic census division, with persistent extreme rates in Georgia and the Carolinas. For whites, low-rate states were concentrated in the Mountain census division and along the northern Atlantic coast. The nonrandom distribution of stroke mortality across the United States, the large magnitude of the difference between high- and low-rate areas, the persistence of the pattern over more than four decades, the similarity of the distribution for different race-gender groups, the lack of delimitation by administrative or political boundaries, and results of national cooperative studies completed in the late 1960s and early 1970s together suggest that the pattern of excess stroke mortality is not an artifact of different diagnostic and reporting practices. Some of the observed geographic variation may be due to both the effects of selective migration and variations in the distributions of stroke risk factors. | [] | https://semanticscholar.org/paper/26c5a7b950919ac32178f74d4f28d6e6b5b44cb8 | [] | [
{
"name": "D J Lanska",
"ids": [
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]
}
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"Medicine"
] | 1,993 | Neurology | Neurology | 43 | 1839 - 1839 | [
"Medline"
] | 10.1212/WNL.43.9.1839 | https://doi.org/10.1212/WNL.43.9.1839 | 8414045 | 2157564338 |
|
c6670f1ed0cc08bc6b5d63d9c468100a09be251b | Simulative corrosion tester for upper deck on oil cargo tank | The utility model belongs to the technical field of material corrosion, and in particular relates to a simulative corrosion tester for an upper deck on an oil cargo tank. The device comprises the following units which are in sealed connection through gas pipelines: a gas source supply unit capable of supplying multiple groups of gases, a flow and test sample temperature control unit (4), a gas mixing unit (5), a corrosion reaction unit (6) and an exhaust gas recycling unit (7). According to the utility model, the actual work condition of the oil cargo tank of an oil tank, which is operated on the sea, is conveniently simulated under the laboratory conditions, so that the experiment conditions are closer to natural conditions, a great number of scientific and reasonable test data is obtained in a shorter time, the simulative corrosion tester is used for predicating the safety of the oil cargo tank in the operating time of 25 years, and the maintenance cost is greatly reduced; meanwhile, the simulative corrosion tester is beneficial to reducing the research development period of a new product of corrosion resistant steel of the oil cargo tank. | [] | https://semanticscholar.org/paper/c6670f1ed0cc08bc6b5d63d9c468100a09be251b | [] | [
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},
{
"name": "薛东妹",
"ids": [
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]
}
] | [] | [] | [
"Engineering"
] | 2,011 | [] | 2759269847 |
||||||||
edd0928654f626ef427b1f2a0570340eadd03797 | Electrical properties of Au-Bn-InP MIS diodes | Capacitance-voltage characteristics of metal-insulator-semiconductor structures of boron nitride on InP have been investigated. The measurements show an overall good capacitance modulation. In accumulation, the frequency dependence of the capacitance of these diodes is consistently attributed to tunneling-related trapping. Bias-temperature-stress (BTS) measurements are used to evaluate the density and sign of the ions which are mobile at 400 K. BTS measurements at 300 K show effects mainly attributed to electron injection from the InP into traps located in the insulator near the interface. | [] | https://semanticscholar.org/paper/edd0928654f626ef427b1f2a0570340eadd03797 | [] | [
{
"name": "O. Baehr",
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{
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},
{
"name": "A. Bath",
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},
{
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},
{
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},
{
"name": "J. Schoonman",
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] | [
"Materials Science"
] | 1,995 | Journal of Non-crystalline Solids | 187 | 409-414 | [] | 10.1016/0022-3093(95)00172-7 | https://doi.org/10.1016/0022-3093%2895%2900172-7 | 2142424699 |
|||
5c7b33b1458b4d9223bf49d1d8830c906730d5ee | Freshman Year Financial Aid Nudges: An Experiment to Increase FAFSA Renewal and College Persistence | In this paper we investigate, through a randomized controlled trial design, the impact of a personalized text messaging intervention designed to encourage college freshmen to refile their Free Application for Federal Student Aid (FAFSA) and maintain their financial aid for sophomore year. The intervention produced large and positive effects among freshmen at community colleges where text recipients were almost 14 percentage points more likely to remain continuously enrolled through the Spring of sophomore year. By contrast, the intervention did not improve sophomore year persistence among freshmen at four-year institutions among whom the rate of persistence was already high. | [] | https://semanticscholar.org/paper/5c7b33b1458b4d9223bf49d1d8830c906730d5ee | [
"http://curry.virginia.edu/uploads/resourceLibrary/29_Freshman_Year_Financial_Aid_Nudges.pdf"
] | [
{
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{
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] | [
"Economics"
] | 2,016 | The Journal of Human Resources | The Journal of Human Resources | 51 | 389 - 415 | [] | 10.3368/jhr.51.2.0614-6458R | https://doi.org/10.3368/jhr.51.2.0614-6458R | 2273877563 |
||
ac2437670d0d1dd9ec3770d768441c0c78f3187e | Fish exclosures versus intensive fishing to restore charophytes in a shallow New Zealand lake | 1.
Disturbance by alien, herbivorous and benthivorous fish species has previously been found to limit the colonization of native charophytes in Lake Rotoroa, Hamilton. This paper compares two methods to reduce the impact of fish on charophyte establishment in this water body.
2.
A 1 ha compartment of the lake was partitioned off and intensively fished by conventional netting methods. A total of 5115 fish, total weight 451 kg, was removed from the compartment over 17 months. Allowing for growth and reproduction within the sampling period, intensive netting reduced the original fish biomass by 86% from about 200 to 28 kg ha−1.
3.
Catfish (Ameiurus nebulosus Le Sueur) comprised 74% of the fish numbers and 57% of the fish biomass. Perch (Perca fluviatilis L.), shortfinned eel (Anguilla australis Richardson), rudd (Scardinius erythrophthalmus L.), tench (Tinca tinca L.), and goldfish (Carassius auratus L.) were present, in order of reducing abundance. These species are alien to New Zealand, with the exception of shortfinned eel.
4.
Charophytes were transplanted inside and outside of the fished 1 ha compartment and their subsequent survival and establishment was monitored. Despite the extensive fish removal from the 1 ha compartment, repeat transplants inside it did not establish in the long term.
5.
Outside of the 1 ha compartment, charophytes were also transplanted into nine 6.25-m2 fish exclosures with netting sides to establish ‘founder colonies’ of charophytes. Within these small exclosures, charophytes established (⩾75% cover) within 1 yr; when five of the exclosures were removed, these unprotected plants survived and expanded over the next year.
6.
This study shows that small exclosures can be used to establish founder colonies of charophytes in the presence of herbivorous and benthivorous fish, and that intensive fish removal is likely to be a less successful and more costly method to restore charophytes in lakes.
Copyright © 2005 John Wiley & Sons, Ltd. | [] | https://semanticscholar.org/paper/ac2437670d0d1dd9ec3770d768441c0c78f3187e | [] | [
{
"name": "Tony M. Dugdale",
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{
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{
"name": "Mary de Winton",
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]
},
{
"name": "Aleki Taumoepeau",
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]
}
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] | [
"Biology"
] | 2,006 | Aquatic Conservation-marine and Freshwater Ecosystems | 16 | 193-202 | [] | 10.1002/AQC.711 | https://doi.org/10.1002/AQC.711 | 2154475208 |
|||
5c5b1b18b3c884518046d1d38b823d7549b50af6 | A 2D graphical representation of RNA secondary structures and the analysis of similarity/dissimilarity based on it | Abstract A 2D graphical representation of RNA secondary structures is given in terms of classifications of bases of nucleic acids. The novel graphical representation can completely avoid loss of information associated with crossing and overlapping of the corresponding curve. Afterwards, we make quantitative analysis for a set of RNA secondary structures at the 3′-terminus of different viruses based on this graphical representation. The examination of similarities/dissimilarities illustrates the utility of the approach. | [] | https://semanticscholar.org/paper/5c5b1b18b3c884518046d1d38b823d7549b50af6 | [] | [
{
"name": "Yu-hua Yao",
"ids": [
"152439291"
]
},
{
"name": "Bo Liao",
"ids": [
"144929603"
]
},
{
"name": "Tian-ming Wang",
"ids": [
"49981183"
]
}
] | [
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] | [
"Chemistry"
] | 2,005 | Journal of Molecular Structure-theochem | 755 | 131-136 | [] | 10.1016/J.THEOCHEM.2005.08.009 | https://doi.org/10.1016/J.THEOCHEM.2005.08.009 | 2017838231 |
|||
e11e29139489a5fad9ce881d9c40322ab987e9c5 | The Development of A Clinical Nursing Practice Guideline for The Patients with Acute Ischemic Stroke in Emergency Department of Sakon Nakhon Hospital | Abstract Acute ischemic stroke was crisis as a cause of sudden death and disability in patients. The accurate and rapid assessment, screening correctly of patients leaded to appropriate treatment, timely and complication reduction. This study aimed to develop a Clinical Nursing Practice Guideline (CNPG) for the patients with acute ischemic stroke. The IOWA Model of evidence-based practice to promote quality care was used as a framework of this study. The practice guideline was developed based on relevant studies and related evidence from the database Institute of Electrical including Blackwell, CINAHL, ProQuest, PubMed and Science direct. Nine researches applied to study from 2004-2014 were selected for possible utilization. Among these studies, one of them was level of evidence I, four of them were level of evidence III, and four were level of evidence IV. The guideline was validated by four experts and was corrected at the parts of assessment method, nursing management in the patient suspect acute Ischemic Stroke, initial management, discharge planning and evaluation. The test for feasibility of the CNPG was conducted among twenty one registered nurses working in an emergency department of Sakon Nakhon Hospital. The results revealed that 90.48 percent of nurses reported the CNPG was feasible for implementing into practice. 85.71 percent of nurses identified that was appropriate to implement at Emergency Department. 80.95 percent of nurses identified that was clarity of feedback on practice and the ability to troubleshoot or cause effects on patients. In addition 70.19 percent of nurses identified that this CNPG was easy to use and economical reduce the cost saving in terms of manpower, time, and budget. The finding of this study suggests that the CNPG should be implementation and outcome evaluation should be considered. Monitor and continuously improved the quality, in accordance with the context of the agency. Keywords: Clinical nursing practice guideline, Acute Ischemic Stroke, Rapid Assessment, Evidence based nursing. | [] | https://semanticscholar.org/paper/e11e29139489a5fad9ce881d9c40322ab987e9c5 | [] | [
{
"name": "Methawinee Khumthong",
"ids": [
"83922420"
]
}
] | [] | [] | [
"Medicine"
] | 2,014 | 17 | 36-55 | [] | 267792485 |
||||||
f73228803ca3d9e444ca6dc8e70b568ccc773f8e | Meyer Wavelet Based Orthogonal Pulse Shaping Algorithm for UWB Communication Systems | In impulse radio (IR) type Ultra-Wideband (UWB) communications, orthogonal waveforms confirm to given spectral mask are desired to improve system capacity. Therefore, in this paper, an orthogonal wavelet based pulse shaping algorithm is proposed and compactly supported Meyer wavelet is used as an example to show how to obtain orthogonal pulses. Simulation results show that the proposed algorithm can obtain orthogonal pulses with high power efficiency and the pulse generator can be implemented simply as well. | [] | https://semanticscholar.org/paper/f73228803ca3d9e444ca6dc8e70b568ccc773f8e | [
"https://doi.org/10.1109/ICC.2008.738"
] | [
{
"name": "Xuanli Wu",
"ids": [
"3032919"
]
},
{
"name": "Xuejun Sha",
"ids": [
"145759310"
]
},
{
"name": "Naitong Zhang",
"ids": [
"1704892"
]
}
] | [
"044b211b782c1bb9a9c5146f85c0a0eb51fe3821",
"560da1d153c8896db795a14ae397f970ccdf53ca",
"dedc82ad42d594d77cbcee8588e99606657cad09",
"cd381e01ee3fad40e6788a8af8e8d871e073bc63"
] | [
"8186e38f8f96673bc268adee43ccfc21d1f11043",
"9a8fd821de989ed2a2e616c561ef6a755d989600",
"d4e0124326fe5464942bc65d4d07e0a37ce5dc9b",
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"bc974ef12be049d206503044a3b996b3e7dddfa1",
"3806298ad780af347b129dfc58ad924f399757c1"
] | [
"Computer Science"
] | 2,008 | 2008 IEEE International Conference on Communications | 2008 IEEE International Conference on Communications | 3928-3932 | [
"DBLP"
] | 10.1109/ICC.2008.738 | https://doi.org/10.1109/ICC.2008.738 | 2102519547 |
|||
571b3d868c5cd54fd9895aa5e92922f6b3b9972f | Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors | Objective: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. Methods: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). Results: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. Conclusion: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family. | [] | https://semanticscholar.org/paper/571b3d868c5cd54fd9895aa5e92922f6b3b9972f | [
"http://ftp.ncbi.nlm.nih.gov/pub/pmc/cd/a3/MIRT-24-66.PMC4563172.pdf",
"http://cms.galenos.com.tr/FileIssue/4/819/article/66-70.pdf"
] | [
{
"name": "Alev Çınar",
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]
},
{
"name": "Murat Sadıç",
"ids": [
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]
},
{
"name": "Hasan İkbal Atılgan",
"ids": [
"1421470066"
]
},
{
"name": "Aylin Baskın",
"ids": [
"40075994"
]
},
{
"name": "Gökhan Koca",
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"153749188"
]
},
{
"name": "Koray Demirel",
"ids": [
"143908506"
]
},
{
"name": "Meliha Korkmaz",
"ids": [
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]
}
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] | [
"Medicine"
] | 2,015 | Molecular imaging and radionuclide therapy | Molecular Imaging and Radionuclide Therapy | 24 | 66 - 70 | [
"Medline"
] | 10.4274/mirt.53215 | https://doi.org/10.4274/mirt.53215 | 26316471 | 1255232309 |
|
46a66e8bcdca7076d914b996e9cf28e791fe66bc | Forward Partnership: A Sustainable American Strategy | Abstract Many commentators now contend that America's power is in relative or absolute decline. However, Declinists overstate their argument, as America has both a commanding amount of residual power and many enduring strengths. Decline, absolute or relative, is not predetermined. However, retaining our influence and preserving our ability to protect and advance U.S. interests does require addressing key shortfalls in strategic priorities to ensure synergies among the components of U.S. national power. A variety of strategies— particularly Offshore Balancing— have been offered to better balance ends, ways and means. These alternatives suffer from policy, historical and implementation challenges. A hybrid solution, Forward Partnering, avoids these deficiencies and is presented as an alternative grand strategy. | [] | https://semanticscholar.org/paper/46a66e8bcdca7076d914b996e9cf28e791fe66bc | [] | [
{
"name": "F. G. Hoffman",
"ids": [
"46805847"
]
}
] | [
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] | [] | [
"Economics"
] | 2,013 | Orbis | 57 | 20-40 | [] | 10.1016/J.ORBIS.2012.10.003 | https://doi.org/10.1016/J.ORBIS.2012.10.003 | 1974221530 |
|||
8cf5e6c4b744a8de033da66206301ed0dc08d2b6 | Self-Adjusting Slot Configurations for Homogeneous and Heterogeneous Hadoop Clusters | The MapReduce framework and its open source implementation Hadoop have become the defacto platform for scalable analysis on large data sets in recent years. One of the primary concerns in Hadoop is how to minimize the completion length (i.e., makespan) of a set of MapReduce jobs. The current Hadoop only allows static slot configuration, i.e., fixed numbers of map slots and reduce slots throughout the lifetime of a cluster. However, we found that such a static configuration may lead to low system resource utilizations as well as long completion length. Motivated by this, we propose simple yet effective schemes which use slot ratio between map and reduce tasks as a tunable knob for reducing the makespan of a given set. By leveraging the workload information of recently completed jobs, our schemes dynamically allocates resources (or slots) to map and reduce tasks. We implemented the presented schemes in Hadoop V0.20.2 and evaluated them with representative MapReduce benchmarks at Amazon EC2. The experimental results demonstrate the effectiveness and robustness of our schemes under both simple workloads and more complex mixed workloads. | [] | https://semanticscholar.org/paper/8cf5e6c4b744a8de033da66206301ed0dc08d2b6 | [
"https://www.cs.umb.edu/~shengbo/paper/tcc15.pdf",
"http://doi.ieeecomputersociety.org/10.1109/TCC.2015.2415802"
] | [
{
"name": "Yi Yao",
"ids": [
"153462555"
]
},
{
"name": "Jiayin Wang",
"ids": [
"2465919"
]
},
{
"name": "Bo Sheng",
"ids": [
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]
},
{
"name": "Chiu Chiang Tan",
"ids": [
"1724352"
]
},
{
"name": "Ningfang Mi",
"ids": [
"145154819"
]
}
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] | [
"Computer Science"
] | 2,017 | IEEE Transactions on Cloud Computing | IEEE Transactions on Cloud Computing | 5 | 344-357 | [
"DBLP"
] | 10.1109/TCC.2015.2415802 | https://doi.org/10.1109/TCC.2015.2415802 | 2333236502 |
||
009f3f40f128f16f538b9ee444cf768e7431d6a8 | Pollen representation of vegetational patterns along an elevational gradient | . Modern pollen assemblages from 16 small lakes (< 2.5 ha) and 11 moderate-sized lakes (4.5–19.3 ha) arrayed along an elevational gradient (300 to 1320 m) in the east-central Adirondack Mountains were studied to determine how well the pollen assemblages recorded patterns of forest composition along the gradient. Forest composition ranges from Pinus strobus/Tsuga/ hardwoods forests at low elevations through Tsuga/ hardwoods, hardwoods, and Picea/Abies forests to Abies-dominated forests at high elevations. Modern pollen percentages for 10 tree taxa were compared with lake elevation using scatter plots and correlation and regression analysis.
Differential smoothing of vegetational patterns along the elevational gradient occurred among the 10 taxa owing to differences in pollen dispersibility, pollen production, and spatial pattern of taxon abundance in forests of the region. No differences were observed in pollen-elevation patterns between small and moderate-sized lakes. Pollen-elevation patterns were obscured for most taxa when the gradient was shortened (e.g. to 600–1320 m) owing to increased spatial smoothing by pollen dispersal. Design and interpretation of paleoecological studies of spatial gradients can be improved by careful attention to site spacing, gradient length, and gradient steepness in the context of pollen dispersal and representation models. | [] | https://semanticscholar.org/paper/009f3f40f128f16f538b9ee444cf768e7431d6a8 | [] | [
{
"name": "Stephen T. Jackson",
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]
}
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] | [
"Biology"
] | 1,991 | Journal of Vegetation Science | 2 | 613-624 | [] | 10.2307/3236172 | https://doi.org/10.2307/3236172 | 2093288260 |
|||
d2fd2e1e207f56f22fe46e72f1c7d53fef0019cd | Detection of cell proliferation in tissue sections. | 1. Cell proliferation is of interest since abnormal cell proliferation appears to be a precursor of tumorigenesis and also because the quantitative description of cell proliferation in tumors can be used to predict the biological behavior of a particular neoplasia. 2. There are several reliable methods of studying cell proliferation in tissues. One of the most important is the detection of the Ki67 defined antigen in frozen sections. The number of cells expressing Ki67 correlates with histological grades of tumors and can also be predictive of clinical outcome. The Ki67 can be localized in tissue sections using monoclonal antibodies in association with the immunoperoxidase technique. 3. Proliferating cell nuclear antigen (PCNA) is a component of DNA polymerase-delta and is another important cell proliferation marker manifesting a striking increase in concentration during the S phase of the cell cycle. 19A2 and PC10 are two different monoclonal antibodies which can be employed to detect PCNA in paraffin-embedded tissues. 4. Molecular biology has also been making a great contribution to the study of cell proliferation. The most recent innovation in tissue identification of proliferating cells is the use of in situ hybridization for the localization of histone H3 and/or H4 mRNA. H3 mRNA-positive cells appear to be present in basal cells of the skin and in crypt cells of the intestine which are sites with high proliferation rate. | [] | https://semanticscholar.org/paper/d2fd2e1e207f56f22fe46e72f1c7d53fef0019cd | [] | [
{
"name": "C E Bacchi",
"ids": [
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]
},
{
"name": "A M Gown",
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}
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"cad9d4bb4a89798f9559fcfe2a3e1f5ca71a1adc"
] | [] | [
"Biology",
"Medicine"
] | 1,993 | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas | 26 7 |
677-87
| [
"Medline"
] | 7903573 | 41026040 |
|||
0dc8acd546a7516f66cf754da6659f473d99842e | The Next Generation of World Trade Policy Development | Over the past 50 years, Europe and North America have worked together to dismantle trade and investment barriers, and have reaped the benefits of extraordinary economic growth, prosperity, and peace. The ultimate testament to the success of these policies has come from the countries to the East and to the South. These countries have decided to abandon their communist and socialist dogmas, and their opposition to open, market-oriented economic policies. This has brought about an end to both the Cold War with the East and the Cold Peace with the South. For the first time in world history it now seems possible to unite the countries of the Earth under truly global economic institutions, founded on principles of economic freedom. And while democracy has not triumphed everywhere, it is more widespread today than ever before. | [] | https://semanticscholar.org/paper/0dc8acd546a7516f66cf754da6659f473d99842e | [] | [
{
"name": "Geza Feketekuty",
"ids": [
"2223330"
]
}
] | [
"ec087be51f750f860076cd68736faadcdcb1b75c"
] | [] | [
"Economics"
] | 2,000 | 119-124 | [] | 10.1007/978-1-4615-4399-2_16 | https://doi.org/10.1007/978-1-4615-4399-2_16 | 139548576 |
|||||
c01e3c4570d10919900c393feed78e5830927aea | Motives , evidence , identity : engaging my critics | My thanks to David Welch for organizing this symposium and to International Theory for publishing it. This is truly generous on the part of the editors as my theory aims to supplant one of theirs as the standard bearer for constructivism. Most of the reviewers provide succinct and accurate overviews of key parts of my theory and offer thoughtful criticisms. Welch notes in his introductory essay that his task was not to provide a critique of A Cultural Theory, but he does raise the question: Why is a feminist perspective excluded from my theory? My reply would be that it is not. Women are central to my treatment of honor, and especially the Homeric understanding of honor. In traditional honor societies, women are described as lascivious and seductive and undue interest in them is thought to sap men’s strength and make them unwilling to risk their lives for honor. As Homer became a foundational text of Western culture, and the Homeric understanding of honor and women was central to subsequent Western societies, my analysis lays bare the origins of misogyny and one of the key reasons why it has remained with us over the millennia. Of equal importance, it highlights how reframing the concept of honor – something now underway in Western societies – has the potential to overcome these negative stereotypes and provide a firmer social foundation for gender equality. Nicholas Rengger questions my choice of motives. He agrees that interest, honor, and fear help to explain a lot of foreign policy. But why stop there? There are other important human motives, among them joy, love, and devotion. He answers his own question by acknowledging that these other motives may not be as relevant to international relations. His second concern is the diversity of Greek thought and my failure to represent it adequately. Hesiod, the Old Oligarch, and Protagoras differ with Thucydides, Plato, and Aristotle on key points. Why do I choose the Greeks I do and how valid is my theory if they are unrepresentative or Symposium on A Cultural Theory of International Relations | [] | https://semanticscholar.org/paper/c01e3c4570d10919900c393feed78e5830927aea | [
"http://www.dartmouth.edu/~nedlebow/mei.pdf?origin=publication_detail"
] | [
{
"name": "James Der Derian",
"ids": [
"84425612"
]
}
] | [
"c4c5ea061050d8713ef7d660b2f0d0df15426d76"
] | [
"cc9d84e5660b425d4c932a350ae41115fd46db84"
] | [] | 2,010 | [] | |||||||||
5bd6aa6bc752fdbab49d63162c55327c0631b737 | Normalization of class hierarchy in databases | In complex object oriented databases, the purpose of introducing class hierarchy is to express ISA semantics, to realize inheriting and to reuse schema definition codes. The schema definition and schema evolution, based on the partial order of lattice, often cause the loss of information inheriting and the redundance of schema definition. Based on the fullness of the inheritance shown by class hierarchy, three normal forms of class hierarchy are given in this paper, and a general algorithm of normalization of class hierarchy is presented, following the Boolean algebra model of class hierarchy. The loss of information inheritance can be avoided when they are applied to schema design and schema evolution. | [] | https://semanticscholar.org/paper/5bd6aa6bc752fdbab49d63162c55327c0631b737 | [
"https://doi.org/10.1007/BF02948479"
] | [
{
"name": "Tianzhu Li",
"ids": [
"40411344"
]
},
{
"name": "Jitian Xiao",
"ids": [
"36123146"
]
},
{
"name": "Zhaohao Sun",
"ids": [
"37087003"
]
},
{
"name": "Xiaofan Bian",
"ids": [
"2617506"
]
}
] | [] | [
"bbb4723d809727adc74be1b6dae3c78d91a37e9e",
"163fa3ed215c6173b4a2df9f2fe42a18b1b1be45",
"42d37a3ffc69f0e2930b03139993bd1159249151",
"71b107c68b3e09793e9bd58d64b94fa6b2613c5e",
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"4bc957eed467807c8c64d22acf80d2d4baa19a55"
] | [
"Computer Science"
] | 2,008 | Journal of Computer Science and Technology | Journal of Computer Science and Technology | 11 | 356-364 | [
"DBLP"
] | 10.1007/BF02948479 | https://doi.org/10.1007/BF02948479 | 2025827964 |
||
c45ea4febad3c3ee580ef0e87add2dac366b023b | Societal Discourses That Help in Family Therapy: A Modified Situational Analysis of the Relationships Between Societal Expectations and Healing Patterns in Parent-Child Conflict | This research inquiry focused on how societal discourses played a role in the ways families experiencing trouble developed strategies to improve their lives. We believe that by looking at how families enact societal discourses for their benefit, family therapists would be better able to support these healthful initiatives. We studied Karl Tomm's idea of healing interpersonal patterns (HIPs), that is, those patterns of interaction that families engage in to counter their problems, specifically in relation to societal discourses. Staff clinicians and student interns of the Calgary Family Therapy Centre conducted the study in the course of their daily work routine, utilizing clinician-friendly research processes we call Research As Daily Practice. The first type of data included the most common HIPs from case records and the second type entailed societal discourses presumed to be helpful. Using situational analysis, we looked for intersections between the HIPs and societal discourses and were able to map the... | [] | https://semanticscholar.org/paper/c45ea4febad3c3ee580ef0e87add2dac366b023b | [] | [
{
"name": "Dan Wulff",
"ids": [
"39848306"
]
},
{
"name": "Sally St. George",
"ids": [
"81805807"
]
},
{
"name": "Karl Tomm",
"ids": [
"10154527"
]
}
] | [
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"e9392dd34bf0761427895c5f4e03a4c31bedf848"
] | [
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"053eb2a339bf1ce8d4be76b90983320c8d09672b"
] | [
"Psychology"
] | 2,015 | Journal of Systemic Therapies | 34 | 31-44 | [] | 10.1521/JSYT.2015.34.2.31 | https://doi.org/10.1521/JSYT.2015.34.2.31 | 2197667170 |
|||
1cb64c111f7ffe47ff909722b7099e9853de094c | Releasing Wolbachia-infected Aedes aegypti to prevent the spread of dengue virus: A mathematical study | Wolbachia is a bacterium that is present in 60% of insects but it is not generally found in Aedes aegypti, the primary vector responsible for the transmission of dengue virus, Zika virus, and other human diseases caused by RNA viruses. Wolbachia has been shown to stop the growth of a variety of RNA viruses in Drosophila and in mosquitoes. Wolbachia-infected Ae. aegypti have both reproductive advantages and disadvantages over wild types. If Wolbachia-infected females are fertilized by either normal or infected males, the offspring are healthy and Wolbachia-positive. On the other hand, if Wolbachia-negative females are fertilized by Wolbachia-positive males, the offspring do not hatch. This phenomenon is called cytoplasmic incompatibility. Thus, Wolbachia-positive females have a reproductive advantage, and the Wolbachia is expanded in the population. On the other hand, Wolbachia-infected mosquitoes lay fewer eggs and generally have a shorter lifespan. In recent years, scientists have successfully released these Wolbachia-adapted mosquitoes into the wild in several countries and have achieved a high level of replacement with Wolbachia-positive mosquitoes. Here, we propose a minimal mathematical model to investigate the feasibility of such a release method. The model has five steady-states two of which are locally asymptotically stable. One of these stable steady-states has no Wolbachia-infected mosquitoes while for the other steady-state, all mosquitoes are infected with Wolbachia. We apply optimal control theory to find a release method that will drive the mosquito population close to the steady-state with only Wolbachia-infected mosquitoes in a two-year time period. Because some of the model parameters cannot be accurately measured or predicted, we also perform uncertainty and sensitivity analysis to quantify how variations in our model parameters affect our results. | [] | https://semanticscholar.org/paper/1cb64c111f7ffe47ff909722b7099e9853de094c | [
"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/4e/main.PMC6962337.pdf"
] | [
{
"name": "Hong Zhang",
"ids": [
"46702533"
]
},
{
"name": "Roger Lui",
"ids": [
"2042285"
]
}
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] | [
"Biology",
"Medicine"
] | 2,020 | Infectious Disease Modelling | Infectious Disease Modelling | 5 | 142 - 160 | [
"Medline"
] | 10.1016/j.idm.2019.12.004 | https://doi.org/10.1016/j.idm.2019.12.004 | 31956742 | 3000529347 |
|
9050ec82d4715baebc2d6570b56b5ae667ac7306 | The reliability and validity of the Goal Orientation and Learning Strategies Survey (GOALS-S): A Filipino investigation | The Goal Orientation and Learning Strategies Survey (GOALS-S; Dowson & McInerney, 2004) is an instrument designed to assess four sets of constructs: (1) academic goals, (2) social goals, (3) cognitive strategies, and (4) metacognitive strategies of high school students. This instrument was initially developed and validated among students in Australia. The applicability of this instrument to the Philippine setting was tested in a study involving 1,147 Filipino students from Metro Manila. Responses to this questionnaire are shown to have good internal consistency reliability. Support is provided for its within-network construct validity in terms of its factorial structure and evidence of its between-network construct validity is shown through its correlations with other valued educational outcomes. Different multigroup confirmatory factor analysis likewise indicated that the instrument is invariant across genders, across year levels, and across type of school. Suggestions for further research using the GOALS-S are provided. | [] | https://semanticscholar.org/paper/9050ec82d4715baebc2d6570b56b5ae667ac7306 | [
"https://works.bepress.com/ronnel_king/8/download/"
] | [
{
"name": "Ronnel B. King",
"ids": [
"2893554"
]
},
{
"name": "David Watkins",
"ids": [
"48739279"
]
}
] | [
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"b47034a5898c26e7bc2b9b71294a9d50c2af1f61"
] | [
"Psychology"
] | 2,011 | Asia-pacific Education Researcher | 20 | 579-594 | [] | 92725090 |
|||||
3d7ed97f0aa706967e48e50c3e352ca00347a83e | An efficient rescaling scheme for computing moving interface problems | Many physical and biological problems can be modeled as moving interface problems. In this talk, we present an efficient rescaling scheme for computing the long-time dynamics of expanding/shrinking interfaces. The idea is to design an adaptive time-space mapping such that in the new time scale, the interfaces evolve following prescribed scaling functions without changing the real physics. We then focus our study on the long-time dynamics of a radial Hele-Shaw problem and demonstrate the efficiency of the rescaling method. | [] | https://semanticscholar.org/paper/3d7ed97f0aa706967e48e50c3e352ca00347a83e | [] | [
{
"name": "shuwang li",
"ids": [
"50341826"
]
}
] | [] | [] | [
"Mathematics"
] | 2,016 | [] | 2510113429 |
||||||||
a776100732870700123164b4d8601e9caa89eb3e | Virtue Ethics and the Value of Saving Humanity | Living in space will no longer be a science fiction in the twenty-first century. However, it remains arguable whether space exploration should be promoted for future space colonization. Some advocates claim that it is necessary because space colonization will be the only option for saving humanity. One plausible option for human settlement in space argues that genetic manipulations of the human mind and body might be required in order to dwell in the hostile environments of space. Such manipulations have various ethical issues such as it might harm several generations before the completion of colonization. Can space colonization under such circumstances be justified from ethical points of view? Utilitarianism and deontology can justify such a colonization because they endorse the assumption that saving humanity has the supreme value. In contrast, this paper argues that virtue ethics can reject the assumption. It concludes that, following a virtue-ethical point of view, ending our lives virtuously is more valuable than surviving even though humankind would cease to exist. | [] | https://semanticscholar.org/paper/a776100732870700123164b4d8601e9caa89eb3e | [] | [
{
"name": "Koji Tachibana",
"ids": [
"71283930"
]
}
] | [] | [
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] | [
"Sociology"
] | 2,020 | 169-181 | [] | 10.1007/978-3-030-42036-9_12 | https://doi.org/10.1007/978-3-030-42036-9_12 | 3048080360 |
|||||
6fb544378be42260f4ae85390407d554f4b2f833 | Student Characteristics Related to Instruction and Learning in Introductory Measurement Courses | This Dissertation is brought to you for free and open access by the Theses and Dissertations at Loyola eCommons. It has been accepted for inclusion in Dissertations by an authorized administrator of Loyola eCommons. For more information, please contact ecommons@luc.edu. hus beon road and <i:?lyrove(l by two membel:'fi of tho faCt.:.1 ty of the Insti t:tte of Indu.'3trial The ::'in3.1 copieS ]lave been ex.;:;.,mined by tho Di:reotor of tho thesis neoessary che.n,ges h.rwc been inool'pora,ted a.:nd the t the thesis is now' given final approval 'Hi th l'ererenC$ to content, forlO, f'..nd mechanical aocuraoy. | [] | https://semanticscholar.org/paper/6fb544378be42260f4ae85390407d554f4b2f833 | [
"http://ecommons.luc.edu/cgi/viewcontent.cgi?article=1838&context=luc_diss",
"https://ecommons.luc.edu/cgi/viewcontent.cgi?article=1838&context=luc_diss",
"https://ecommons.luc.edu/cgi/viewcontent.cgi?article=1838&context=luc_diss&httpsredir=1&referer="
] | [
{
"name": "Anne D. Kennard",
"ids": [
"69030499"
]
}
] | [] | [] | [
"Psychology"
] | 1,967 | [] | 35116461 |
||||||||
4d7fe321a04eecbc91d733d93209859d07eb2db3 | Multibunch operation in the Tevatron Collider | The Tevatron Collider at Fermilab is the world's highest energy hadron collider, colliding protons with antiprotons at a center of mass energy of 1800 GeV. At present six proton bunches collide with six antiproton bunches to generate luminosities of up to 9/spl times/10/sup 30/ cm/sup -2/ s/sup -1/. It is estimated that to reach luminosities significantly greater than 10/sup 31/ cm/sup -2/ s/sup -1/ while minimizing the number of interactions per crossing, the number of bunches will have to be increased. Thirty-six bunch operation looks like the most promising plan. This paper looks at the strategies for increasing the number of particle bunches, the new hardware that needs to be designed and changes to the operating mode in filling the Tevatron. An interactive program which simulates the filling of the Tevatron collider is also presented. The time scale for multibunch operation and progress towards running greater than six bunches is given in this paper.<<ETX>> | [] | https://semanticscholar.org/paper/4d7fe321a04eecbc91d733d93209859d07eb2db3 | [] | [
{
"name": "J. A. Holt",
"ids": [
"144625896"
]
},
{
"name": "D. A. Finley",
"ids": [
"145218141"
]
},
{
"name": "V. Bharadwaj",
"ids": [
"73257284"
]
}
] | [] | [
"b9f7ba3b88b3ad31199ecff099fe9d3b3c1ba52c"
] | [
"Physics"
] | 1,993 | Proceedings of International Conference on Particle Accelerators | Proceedings of International Conference on Particle Accelerators | 3806-3807 vol.5 | [] | 10.1109/PAC.1993.309807 | https://doi.org/10.1109/PAC.1993.309807 | 2989109166 |
|||
6b2ae6eb4430c3e50d0810c03d6432e236e46c9d | Evaluating the effects of immunosuppression by in-vivo bioluminescence imaging after allotransplantation of ovarian grafts. | Bioluminescence imaging (BLI) has been introduced for studies of ongoing biological processes but has never been applied for ovarian transplantation. Here, BLI was used as a novel approach to trace the survival of ovarian grafts. The ovarian donors were transgenic mice carrying FVB/N-Tg (PolII-luc) as a reporter gene, encoding luciferase to catalyse luciferin which results in visible light emission as bioluminescence. There were three groups of recipients: (i) group A: BALB/c mice without immunosuppressant treatment; (ii) group B: BALB/c mice receiving a cocktail immunosuppressant treatment; and (iii) group C: immunodeficient NOD-SCID mice without immunosuppression. Luciferin BLI was used to follow graft survival, and viable follicle numbers were counted as a measure of success. Bioluminescence intensity fluctuated but was consistent with the end-point counts of viable follicle numbers. Group A showed loss of viable follicles and bioluminescence disappeared as early as day 10 following ovarian engraftment, indicating strong immune rejection. Groups B and C showed graft survival and measurable bioluminescence for up to 30 days. In conclusion, BLI provided non-invasive longitudinal dynamic monitoring of ovarian grafts with excellent sensitivity and spatial resolution. This approach should prove valuable for research on ovarian transplantation. | [] | https://semanticscholar.org/paper/6b2ae6eb4430c3e50d0810c03d6432e236e46c9d | [] | [
{
"name": "Yi-Hsin Lin",
"ids": [
"46393392"
]
},
{
"name": "Yu-Chi Yeh",
"ids": [
"6176844"
]
},
{
"name": "Chii-Ruey Tzeng",
"ids": [
"79928770"
]
},
{
"name": "Wei-Jen Shang",
"ids": [
"13581802"
]
},
{
"name": "Jah-Yao Liu",
"ids": [
"4058430"
]
},
{
"name": "Chi-Huang Chen",
"ids": [
"2080117"
]
}
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] | [
"Biology",
"Medicine"
] | 2,011 | Reproductive biomedicine online | Reproductive biomedicine online | 22 2 |
220-7
| [
"Medline"
] | 10.1016/j.rbmo.2010.10.010 | https://doi.org/10.1016/j.rbmo.2010.10.010 | 21233017 | 2027326133 |
|
c674d7fa6f8335bb3273a3e6e7cc456f8184c1d4 | Hybrid wired/wireless OFDM-PON with direct modulation of integrated lasers employing optical injection | In this paper the transmission of OFDM based wired/wireless services for hybrid PONs using direct modulation is studied. For overcoming the limitations imposed by direct modulation of cost effective low bandwidth laser transmitters we make use of novel monolithically integrated Discrete Mode lasers and optical injection. The system includes a wired OFDM signal operating at 12.5 Gb/s and three wireless signals delivering Long Term Evolution (LTE) services encoded with 16 QAM. We show experimentally how the limitations enforced in such hybrid systems when direct modulation is applied to low bandwidth lasers can be overcomed by employing optical injection. Results obtained for back to back transmission as well as over 50 km of fibre are presented, and system performance is evaluated for various relative power ratios of the wired/wireless signals. | [] | https://semanticscholar.org/paper/c674d7fa6f8335bb3273a3e6e7cc456f8184c1d4 | [] | [
{
"name": "Arsalan Saljoghei",
"ids": [
"7356407"
]
},
{
"name": "Colm Browning",
"ids": [
"7360284"
]
},
{
"name": "Liam Barry",
"ids": [
"35154189"
]
}
] | [
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] | [
"Engineering"
] | 2,013 | 2013 IEEE International Topical Meeting on Microwave Photonics (MWP) | 2013 IEEE International Topical Meeting on Microwave Photonics (MWP) | 309-312 | [] | 10.1109/MWP.2013.6724083 | https://doi.org/10.1109/MWP.2013.6724083 | 2018775344 |
|||
c05e6d50d60b996bf6787c32b98362371f7fb704 | Sex Lives and Audiotape: Geography, Sexuality, and Undergraduate Dissertations. | Abstract The dissertation is commonly the largest piece of work conducted by UK geography undergraduates. There has been an increase in dissertations on topics grouped under the heading ‘sexual geographies’. This paper addresses some of the practicalities in doing a dissertation on sexual geographies, from choosing a topic to selecting a relevant methodological framework. It also draws attention to issues in the ethics of independent research in this area. | [] | https://semanticscholar.org/paper/c05e6d50d60b996bf6787c32b98362371f7fb704 | [] | [
{
"name": "David Bell",
"ids": [
"49921700"
]
}
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"8372ec59880e5f985491599e7dd1080bae47d969",
"b6aa80838a44efeaa38aff7254c3bcab7efe77c4"
] | [
"Sociology"
] | 1,997 | Journal of Geography in Higher Education | 21 | 411-417 | [] | 10.1080/03098269708725446 | https://doi.org/10.1080/03098269708725446 | 1975379871 |
|||
bc5d94fab7476fa3ae3fa9ec9456f0fc807920ec | Boston children's hospital community asthma initiative: Five-year cost analyses of a home visiting program | Abstract Objective: To evaluate the costs and benefits of the Boston Children's Hospital Community Asthma Initiative (CAI) through reduction of Emergency Department (ED) visits and hospitalizations for the full pilot-phase program participants. Methods: A cost-benefit analyses was conducted using hospital administrative data to determine an adjusted Return on Investment (ROI): on all 268 patients enrolled in the CAI program during the 33-month pilot program phase of CAI intervention between October 1, 2005 and June 30, 2008 using a comparison group of 818 patients from a similar cohort in neighboring ZIP codes without CAI intervention. Cost data through June 30, 2013 were used to examine cost changes and calculate an adjusted ROI over a 5-year post-intervention period. Results: CAI patients had a cost reduction greater than the comparison group of $1,216 in Year 1 (P = 0.001), $1,320 in Year 2 (P < 0.001), $1,132 (P = 0.002) in Year 3, $1,123 (P = 0.004) in Year 4, and $997 (P = 0.022) in Year 5. Adjusting for the cost savings for the comparison group, the cost savings from the intervention resulted in an adjusted ROI of 1.91 over 5 years. Conclusions: Community-based, multidisciplinary, coordinated disease management programs can decrease the incidence of costly hospitalizations and ED visits from asthma. An ROI of greater than one, as found in this cost analysis, supports the business case for the provision of community-based asthma services as part of patient-centered medical homes and Accountable Care Organizations. | [] | https://semanticscholar.org/paper/bc5d94fab7476fa3ae3fa9ec9456f0fc807920ec | [] | [
{
"name": "Urmi Bhaumik",
"ids": [
"10064316"
]
},
{
"name": "Susan J Sommer",
"ids": [
"7146756"
]
},
{
"name": "Judith Giller-Leinwohl",
"ids": [
"1432973694"
]
},
{
"name": "Kerri Norris",
"ids": [
"49815285"
]
},
{
"name": "Lindsay Tsopelas",
"ids": [
"11185237"
]
},
{
"name": "Shari Nethersole",
"ids": [
"10061319"
]
},
{
"name": "Elizabeth R Woods",
"ids": [
"48557410"
]
}
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] | [
"Medicine"
] | 2,017 | The Journal of asthma : official journal of the Association for the Care of Asthma | Journal of Asthma | 54 | 134 - 142 | [
"Medline"
] | 10.1080/02770903.2016.1201837 | https://doi.org/10.1080/02770903.2016.1201837 | 27624870 | 2519382228 |
|
e1f1e8536fbf97bb0b4d99aab00d506a6efc591a | An Ethnoarchaeological Approach to the Seasonality of Historic Cree Sites in Central Québec | Determining site seasonality in the eastern Canadian Subarctic is crucial to the interpretation of settlement patterns of both prehistoric and modern hunters and gatherers. Ethnoarchaeology provides a conceptual framework through which ethnographic informants are used to develop an archaeological model of site seasonality for recent historic sites. This research has led to the development of an hypothesis that structure form, hearth type, and floor preparation can be used to predict site seasonality. Key words: ethnoarchaeology, Cree, Naskapi, Montagnais, land use, structure types | [] | https://semanticscholar.org/paper/e1f1e8536fbf97bb0b4d99aab00d506a6efc591a | [
"http://pubs.aina.ucalgary.ca/arctic/Arctic36-4-350.pdf"
] | [
{
"name": "Christopher C. Hanks",
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"35348843"
]
}
] | [
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"5bd9f34eb936c746e63ec01c5619b69f3ce7dbe4",
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"eb637acaefe162723b7acd39ec8110ed7b2ba67b",
"a122246e645f4df8aece1cbfe969939811d044ab",
"2c9f9437d7dab8f821275c61e7b4be989528245b",
"f8acc6eeb00344bf8c40a6343416259d371bf438",
"9d3f548089174c905e2e2dc59c01caf332c8c236",
"019458b7a87e4bb59f2fb40e024a483d0f62ab26",
"4fc4e8d79bad7f807326f95a2796c72fd0391e4c"
] | [
"1cb4197575419f167d4c62aaf7a6383245899629",
"e8a7770d1a9fd50c5178f9023a2f93fc425524b7",
"d083294e6ab0ac912175bb8e339d9443b01eae75"
] | [
"Geology"
] | 1,983 | Arctic | 36 | 350-355 | [] | 10.14430/ARCTIC2289 | https://doi.org/10.14430/ARCTIC2289 | 2109108486 |
|||
b94103a9f569e6af716d4496f1106b3e16164413 | PO-321 MicroRNA-145 and COX2 levels are regulated by nerve growth factor (NGF) in epithelial ovarian cancer | Introduction In many type of cancer, including epithelial ovarian cancer (EOC), nerve growth factor (NGF) and its high affinity receptor TRKA are over-expressed and also are involved in proliferation and angiogenesis. On the other hand, many inflammatory molecules such as cyclooxigenase-2 (COX-2) and prostaglandins (PGE2) are over-expressed in cancer and also involved in the progression of cancer. Besides, a deregulation of some miRs expression has been described in EOC including miR-145 among others. The relationship of NGF-mirRs-COX2 in EOC has not been studied. Then, the aim of this work was to evaluate COX-2 and miR-145 levels in EOC progression and the changes of COX-2 and miR-145 levels by NGF action in epithelial ovarian cancer cell line (A2780). Also we evaluated COX-2 levels by Western-Blot after over-expression of miR-145 in A2780 cell line. Material and methods Thirty human ovarian tissues (normal, tumour and cancer) were obtained from Obstetrics and Gynaecology Department, Clinical Hospital, University of Chile and also from National Institute of Cancer with written consent and authorised by Ethic Committee of the Institutions. The COX-2 levels in tissues and cells were measured by RT-PCR, IHQ, and Western-Blot and miR-145 was measured by qPCR. Cells A2780 were stimulated with NGF (100 and 150 ng/ml) to measure COX-2 and miR-145 levels. Besides, over-expression of miR-145 was done by transfection assays with lipofectamine-2000 to evaluate cellular invasion and also transduction assays with lenti-virus in order to evaluate COX-2 levels by Western-Blot in A2780 cell line. Results and discussions It was found a significant decrease of miR-145 levels in EOC tissues compared with tumour tissues and normal ovarian tissues (p<0.05). On the other hand, a significant increase of COX-2 levels was found in EOC tissues compared with tumours and normal tissues (p<0.05). The activation of TRKA receptor by NGF induced a significant decrease of miR-145 levels (p<0.05) and a significant increase of COX-2 levels (p<0.05) in epithelial ovarian cancer cell line A2780. When miR-145 was over-expressed in A2780 cells, a significant decrease of COX-2 levels was found (p<0.05). These results support the role of NGF in the regulation of miRs and inflammatory molecules in EOC. Conclusion MicroRNA-145 acts as tumour suppressor microRNA in ovarian cancer and these results suggest that miR-145 could be a good therapy for EOC. This work was supported by Grant: Fondecyt 1160139 to CR and ACCDIS - Conicyt-Fondap 15130011 | [] | https://semanticscholar.org/paper/b94103a9f569e6af716d4496f1106b3e16164413 | [] | [
{
"name": "Carmen Romero",
"ids": [
"145338306"
]
},
{
"name": "L Lobos",
"ids": [
"33319891"
]
},
{
"name": "I. Hurtado",
"ids": [
"152815265"
]
},
{
"name": "Carolina Vera",
"ids": [
"120550633"
]
},
{
"name": "I Gallegos",
"ids": [
"3759762"
]
},
{
"name": "J Chnaiderman",
"ids": [
"4698345"
]
},
{
"name": "Margarita Vega",
"ids": [
"145081571"
]
},
{
"name": "Alberto Selman",
"ids": [
"50459521"
]
},
{
"name": "P Gayan",
"ids": [
"153476242"
]
}
] | [] | [] | [
"Medicine"
] | 2,018 | ESMO Open | 3 | A354 - A354 | [] | 10.1136/esmoopen-2018-EACR25.834 | https://doi.org/10.1136/esmoopen-2018-EACR25.834 | 2810250300 |
|||
045b3e3482a5e639439b48f5d0f132a163788fa3 | Risk-aware navigation for UAV digital data collection | This thesis studies the navigation task for autonomous UAVs to collect digital data in a risky environment. Three problem formulations are proposed according to different real-world situations. First, we focus on uniform probabilistic risk and assume UAV has unlimited amount of energy. With these assumptions, we provide the graph-based Data-collecting Robot Problem (DRP) model, and propose heuristic planning solutions that consist of a clustering step and a tour building step. Experiments show our methods provide high-quality solutions with high expected reward. Second, we investigate non-uniform probabilistic risk and limited energy capacity of UAV. We present the Data-collection Problem (DCP) to model the task. DCP is a grid-based Markov decision process, and we utilize reinforcement learning with a deep Ensemble Navigation Network (ENN) to tackle the problem. Given four simple navigation algorithms and some additional heuristic information, ENN is able to find improved solutions. Finally, we consider the risk in the form of an opponent and limited energy capacity of UAV, for which we resort to the Data-collection Game (DCG) model. DCG is a grid-based two-player stochastic game where the opponent may have different strategies. We propose opponent modeling to improve data-collection efficiency, design four deep neural networks that model the opponent’s behavior at different levels, and empirically prove that explicit opponent modeling with a dedicated network provides superior performance. RISK-AWARE NAVIGATION FOR UAV DIGITAL DATA COLLECTION by Zhi Xing B.S., Nankai University, 2010 M.S., Syracuse University, 2017 Dissertation Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Computer and Information Science and Engineering. Syracuse University August 2017 Copyright c © Zhi Xing 2017 All Rights Reserved | [] | https://semanticscholar.org/paper/045b3e3482a5e639439b48f5d0f132a163788fa3 | [
"https://surface.syr.edu/cgi/viewcontent.cgi?article=1777&context=etd"
] | [
{
"name": "Zhi Xing",
"ids": [
"145199541"
]
}
] | [] | [
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"aa8e4263ef59d095dc0f87fb0dae19b441bfa6c5",
"5671b02a233f9ce2562c4982db2875b17787f3c6",
"ca69b23f49a398489e78aedfce5e57a56560b6c9",
"45786063578e814444b8247028970758bbbd0488",
"5ce9712a446bbeaac2d04b1f74aea37115c59c5e",
"abd1c342495432171beb7ca8fd9551ef13cbd0ff",
"d407127016cc93bff84888a66538e2803747d26c",
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"65601b92138dc67b78be35d67b11e7fd77af1026",
"b34aa0606626cf170118e81d11dec701598ee6d9",
"a6547a35e3a87a65347e2cf077ef6f1aac278a39",
"c6170fa90d3b2efede5a2e1660cb23e1c824f2ca",
"4c05d7caa357148f0bbd61720bdd35f0bc05eb81",
"2cd8a4500d9cd0b52ed026204f20f8aad539caeb",
"8e8e4af155def064b66ff7badd37173b6994bd51",
"9e1cb0c7006be36a3a72e2d1c75b27ced16a5f42",
"4f8d648c52edf74e41b0996128aa536e13cc7e82"
] | [
"Computer Science"
] | 2,017 | [] | 2886274875 |
||||||||
5ab7da2b6f34e9f0173b94a6aa566a855dab014d | Abstract 3419: Frequency and function of ERBB3 mutations in bladder cancer | Deregulation of the HER family of receptor tyrosine kinases has been widely implicated in cancer initiation and progression. Activating mutations or gene amplification of EGFR and ERBB2 (HER2) are frequently found in non-small cell lung, breast, colorectal, glioblastoma and head and neck cancers. However, little is known regarding the prevalence or functionality of genomic alterations in the ERBB3 (HER3) isoform. Although ERBB3 has limited inherent kinase activity, ligand stimulation promotes its dimerization with active kinases like ERBB2 and EGFR that can phosphorylate ERBB3 which then promotes transformation. Thus genomic alterations in ERBB3 may be a key means of promoting oncogenic signaling despite the protein lacking robust enzymatic activity. We performed a meta-analysis of 40 cross-cancer next generation sequencing and copy number genomics data sets newly generated by our group (bladder) or found in recently published repositories (The Cancer Genome Atlas (TCGA), Broad, Genentech, Sanger, etc). Analogous to the singular 2013 publication on ERBB3 mutations to date, we found frequent mutations in ERBB3 in gastric tumors (∼11%). Preliminary analysis of our novel and expanding cohort of 109 high-grade bladder cancer tumors suggests that ERBB3 mutations are equally frequent in bladder cancer (∼10-12%). Collectively, EGFR, ERBB2 and ERBB3 alterations were found in 23-30% of all high-grade bladder cancers, typically in a mutually exclusive pattern suggesting that these may be driver events. ERBB3 mutations were distributed across all structural domains of the protein. We identified more than 15 novel ERBB3 mutations in our bladder cohort, including hotspot mutations in the extracellular domain (V104L/M, D297Y, others) that were recurrent across multiple cancers types. Stable retroviral overexpression of ERBB3 mutants into NIH-3T3 cells induced phosphorylation of ERBB3, activation of downstream signaling cascades and soft agar colony formation, all which were enhanced in the presence of neuregulin and inhibited by the dual EGFR/ERBB2 kinase inhibitor, neratinib, and a monoclonal antibody to ERBB3, AMG-888/U3-1287. These data highlight a large cohort of bladder cancer patients with novel, activating mutations in the tractable kinase ERBB3, that could potentially benefit from approved EGFR/ERBB2 targeted therapeutics in the clinic and novel ERBB3 therapeutics in early clinical trials. Citation Format: Aphrothiti J. Hanrahan, John P. Sfakianos, Ricardo Ramirez, Phillip H. Kim, Gopa Iyer, Hikmat A. Al-Ahmadie, Sasinya N. Scott, Dean F. Bajorin, Bernard H. Bochner, Jonathan A. Coleman, Jonathan E. Rosenberg, Michael F. Berger, Sarat Chandarlapaty, David B. Solit. Frequency and function of ERBB3 mutations in bladder cancer. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3419. doi:10.1158/1538-7445.AM2014-3419 | [] | https://semanticscholar.org/paper/5ab7da2b6f34e9f0173b94a6aa566a855dab014d | [] | [
{
"name": "Aphrothiti J. Hanrahan",
"ids": [
"7443737"
]
},
{
"name": "John P. Sfakianos",
"ids": [
"4661349"
]
},
{
"name": "Ricardo Ramirez",
"ids": [
"143906048"
]
},
{
"name": "Phillip H. Kim",
"ids": [
"15733774"
]
},
{
"name": "Gopa Iyer",
"ids": [
"1735079"
]
},
{
"name": "Hikmat Al-Ahmadie",
"ids": [
"1395627720"
]
},
{
"name": "Sasinya N. Scott",
"ids": [
"3934677"
]
},
{
"name": "Dean F. Bajorin",
"ids": [
"4286268"
]
},
{
"name": "Bernard H. Bochner",
"ids": [
"3950808"
]
},
{
"name": "Jonathan A. Coleman",
"ids": [
"50253109"
]
},
{
"name": "Jonathan E. Rosenberg",
"ids": [
"3081472"
]
},
{
"name": "Michael F. Berger",
"ids": [
"33727638"
]
},
{
"name": "Sarat Chandarlapaty",
"ids": [
"6037809"
]
},
{
"name": "David B. Solit",
"ids": [
"2344124"
]
}
] | [
"14b182dcc067d5cfacfb83dc234a63181a3fdb28"
] | [] | [
"Biology"
] | 2,014 | Cancer Research | 74 | 3419-3419 | [] | 10.1158/1538-7445.AM2014-3419 | https://doi.org/10.1158/1538-7445.AM2014-3419 | 1995024679 |
|||
9dba1f5297c98a17d006c78c7a3c39952d064b5e | Involvement of miR-338-5p in antibody-mediated renal allograft rejection by targeting TRAF3 | Objective To explore the significantly differentially.expressed microRNAs during antibody-mediated renal allograft rejection.Method MicroRNA array assay was used,and the obtained data were analyzed by bioinformatics analysis.The obtained significant microRNAs were further analyzed to forecast the targeted genes in the common database,then experimental means were used to testify the targeted genes.Result During the antibody-mediated renal allograft rejection,the significantly over-expressed microRNAs were miR-200c,miR-200b,miR-30c,miR-30b and miR-30e+,etc.The significantly down-expressed microRNA was miR-338-5p.The bioinformatics analysis results indicated that TRAF3 was the targeted gene of miR-338-5p,which was testified by real time PCR,immunohistochemical assay and fluorescence reporter assay.Conclusion miR-338-5p anticipated in the antibody-mediated renal allograft rejection by targeting TRAF3.
Key words:
Kidney transplantation; Antibody; Rejection; microRNA | [] | https://semanticscholar.org/paper/9dba1f5297c98a17d006c78c7a3c39952d064b5e | [] | [
{
"name": "Hai-yan Xu",
"ids": [
"153194469"
]
},
{
"name": "Xiao-zhou He",
"ids": [
"15486086"
]
},
{
"name": "Xu-yi Ma",
"ids": [
"13806960"
]
},
{
"name": "Dong Xue",
"ids": [
"30743939"
]
}
] | [
"c8a86ee5e77a296fccf37789d73b9b5a4df2549b"
] | [] | [
"Medicine"
] | 2,013 | Chineae Journal of Organ Transplantation | 34 | 554-558 | [] | 10.3760/CMA.J.ISSN.0254-1785.2013.09.011 | https://doi.org/10.3760/CMA.J.ISSN.0254-1785.2013.09.011 | 3032085010 |
|||
e16400e31ac15da0e99b7c655aa7d80262896ba9 | [Study on the chemical constituents from Clematis brevicaudata]. | OBJECTIVE
To study the chemical constituents from Clematis brevicaudata.
METHODS
The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis (NMR).
RESULTS
Eight compounds were isolated and identified as: palmitic acid (1), 1-docosanol (2), pentacosanoic acid-2', 3'-dihydroxypropyl ester (3), beta-sitosterol (4), daucosterol (5), a mixture of the trans-p-coumarate of the n-alkanols (6), 3,4-dihydroxy-trans coumatate ethyl ester (7), syringaresinol-O-D-glucopyranoside (8).
CONCLUSION
All these compounds are obtained from Clematis brevicaudata for the first time. | [] | https://semanticscholar.org/paper/e16400e31ac15da0e99b7c655aa7d80262896ba9 | [] | [
{
"name": "Ai-Mei Yang",
"ids": [
"4645029"
]
},
{
"name": "Jing Du",
"ids": [
"47725363"
]
},
{
"name": "Zhong-Huan Miao",
"ids": [
"120314944"
]
},
{
"name": "Hui-Jun Yuan",
"ids": [
"46609007"
]
}
] | [
"d93a7d8ff5d641de98081460c275be6d10f6424d"
] | [] | [
"Chemistry",
"Medicine"
] | 2,009 | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | 32 10 |
1534-7
| [
"Medline"
] | 20112713 | 2376514586 |