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leminda-ai

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0c08204a99c45a07ebdec6aacdd3adc2bab9b9ea

Correction of Defective Interdomain Interaction Within Ryanodine Receptor by Antioxidant Is a New Therapeutic Strategy Against Heart Failure

Background— Defective interdomain interaction within the ryanodine receptor (RyR2) seems to play a key role in the pathogenesis of heart failure, as shown in recent studies. In the present study we investigated the effect of oxidative stress on the interdomain interaction, its outcome in the cardiac function in heart failure, and the possibility of preventing the problem with antioxidants. Methods and Results— Sarcoplasmic reticulum (SR) vesicles were isolated from dog left ventricular (LV) muscle (normal or rapid ventricular pacing for 4 weeks with or without the antioxidant edaravone). In the edaravone-treated paced dogs (EV+), but not in the untreated paced dogs (EV−), normal cardiac function was restored almost completely. In the SR vesicles isolated from the EV−, oxidative stress of the RyR2 (reduction in the number of free thiols) was severe, but it was negligible in EV+. The oxidative stress of the RyR2 destabilized interdomain interactions within the RyR2 (EV−), but its effect was reversed in EV+....

https://semanticscholar.org/paper/0c08204a99c45a07ebdec6aacdd3adc2bab9b9ea

2887844081

f78addbd7c5c12248480be00f5cd02c3c9e10b64

Chantal Akerman: Moving Through Time and Space

Since 1968, Brussels-born, Paris-based Chantal Akerman has produced over 50 film and video works, in the genres of documentary and French New Wave-inspired fictional narrative. She is one of the foremost auteur-directors working today, yet she has never had a solo museum exhibition in the United States, nor has there been significant scholarly inquiry into her body of work. Her early experiments with Structuralist, Marxist and Feminist filmmaking have expanded what is possible in film today. Asserting Akerman's contribution to the genre, this volume introduces her work to those who have not had a chance to see it firsthand. With interpretive and anecdotal commentary on Akerman's oeuvre, the documentary films covered here have not been explored elsewhere.

https://semanticscholar.org/paper/f78addbd7c5c12248480be00f5cd02c3c9e10b64

581346263

0552bab526d6b2658f2fc0db8495b7cc605e8fac

The Proof and Application For a Theorem In Hilbert Space

In this paper,We have derived a theorem on operator norm in Hilbert space.By use of this theorem,We may derive two results of optimum in pertuba-tion problems with respect to spectral Condition number to Generalized inv-erse of Column(or row)full rank matrix.

https://semanticscholar.org/paper/0552bab526d6b2658f2fc0db8495b7cc605e8fac

2372205275

247710ff920935a52c201b1a51394e48546333ef

Two-dimensional electron gas in a metal/amorphous oxide interface with spin orbit interaction

The formation of novel two-dimensional electron gas (2DEG) with high mobility in metal/amorphous interfaces has motivated an ongoing debate regarding the formation and novel characteristics of these 2DEGs. Here we report an optical study, based on infrared spectroscopic ellipsometry, of nonmagnetic metal and amorphous semiconducting oxide (Cu/Bi$_2$O$_3$) interfaces that confirms the formation of a 2DEG with spin orbit coupling (SOC). The 2DEG optical response was simulated with a uniaxial diagonal dielectric tensor within a sub-nanometer thin layer, where its $x$ and $z$ components lineshapes resolved in both free-electron and peak-like contributions, resulted very similar to theoretical predictions [M. Xie et al., Phys. Rev. B $\bf{89}$, 245417 (2014)] of a two dimensional electron gas confined in the normal direction of a perovskite interface. In particular, the small but finite conducting character of the $z$ component provides a unambiguous signature of the presence of the 2DEG in the Cu/Bi$_2$O$_3$ system. Although the original constituent materials do not possess spin-orbit coupling (SOC), the resulting interfacial hybridization of such states induce electronic asymmetric wave functions. This work demonstrates the detection of 2DEG in amorphous crystals allowing to study its challenging interfacial phenomena such as SOC and interface-bulk coupling, overcoming an experimental impediment which has hold back for decades important advancements for the understanding of 2DEGs in amorphous materials.

https://semanticscholar.org/paper/247710ff920935a52c201b1a51394e48546333ef

Physical Review B

100

235449

10.1103/PhysRevB.100.235449

https://doi.org/10.1103/PhysRevB.100.235449

2914905796

76bbad87f6c3a590aaa3e55aa822b72971caec16

Compound Verbal Stimuli and Word Association

In two replications, 97 and 122 Williams College students in elementary psychology classes were given two lists of word pairs with instructions to give a discrete free associate to each pair. List A contained word-pairs designed to increase the frequency of the normative primary responses and List B contained pairs designed to increase the range of responses. The results showed that significantly fewer different responses and significantly higher frequencies for the primary responses were given to List A than to List B. Compared to the single-word norms, responses to List A had higher, and to List B, lower, commonality. Two factors were used in constructing List A: (1) the stimulus pair denoted or connoted a third word; (2) in common speech, a third word frequently follows the stimulus pair. The List B pairs lacked these factors, or had them in a low degree.

https://semanticscholar.org/paper/76bbad87f6c3a590aaa3e55aa822b72971caec16

Psychological reports

Psychological Reports

17

403 - 406

10.2466/pr0.1965.17.2.403

https://doi.org/10.2466/pr0.1965.17.2.403

5833257

1965362027

63b8a82b3143c1a354a045f998dce642ec2dd35d

Effects of Essential Oils to Control Rhizopus stolonifer in vitro and in vivo on Strawberry

The aim of this study was to evaluate the antifungal effects of essential oils (fennel, black caraway and anis) at different concentrations against the fungal pathogen, Rhizopus stolonifer, the causal agent of smooth rot disease of strawberry (Fragaria ananassa Duch.) under in vitro and in vivo conditions.The results of in vitro showed the growth of R. stolonifer was completely

https://semanticscholar.org/paper/63b8a82b3143c1a354a045f998dce642ec2dd35d

Archives of Phytopathology and Plant Protection

8

621141266

e87348ad354397240d8a29829e5fdfa9517c6f8e

Angiotensin II regulates endothelial cell migration through calcium influx via T‐type calcium channel in human umbilical vein endothelial cells

Aim:  The T‐type calcium channel is expressed in vascular endothelial cells, but its role in endothelial cell function is yet to be elucidated. We analysed the endothelial functional role of T‐type calcium channel‐dependent calcium under angiotensin II (Ang II) stimulation.

https://semanticscholar.org/paper/e87348ad354397240d8a29829e5fdfa9517c6f8e

Acta physiologica

Acta Physiologica

198

10.1111/j.1748-1716.2009.02070.x

https://doi.org/10.1111/j.1748-1716.2009.02070.x

20028346

1967487388

4661648b37b718ddd66b91b259f58480257c6ace

A Classification System for Fat Necrosis in Autologous Breast Reconstruction

PurposeFat necrosis (FN) is a common complication of autologous breast reconstruction, yet no classification system exists to describe it. We sought to develop and validate a tool for meaningful reporting, comparison of techniques, and treatment planning. Our hypothesis was that a valid classification system would demonstrate higher grades of FN for pedicled transverse rectus abdominus myocutaneous (pTRAM) flaps as compared to free flaps (FF). MethodsA classification system for FN was developed: grade I, radiologic evidence only; grade II, palpable but not visible FN; grade III, palpable and visible FN; and grade IV, symptomatic FN. For validation, we applied this system to patients who had undergone pTRAM flaps from 2002 to 2006 and FF from 2006 to 2010 at our institution. ResultsWe performed 93 pTRAM flaps in 69 patients and 102 FF in 69 patients. One patient had grade I FN and was observed. Of the 29 patients with grade II FN, 48% were observed, 17% had biopsy, and 35% underwent debridement. Of the 9 patients with grade III FN, 11% underwent biopsy and 89% had debridement. All patients with grade IV FN underwent debridement. The distribution of FN differed between pTRAM and FF. The mean FN grade for patients undergoing pTRAM was 1.4 versus 0.4 for those undergoing FF (P < 0.05). Fat necrosis requiring reoperation was more frequent in the pTRAM group (23.7% vs 5.9%, P < 0.05). ConclusionsOur validation study confirmed that FN grade was associated with the need for surgery and was higher for pedicled flaps as compared to FFs. As it is similar to the Baker grading system for capsular contracture, this classification system is familiar to all plastic surgeons. It is simple, easy to remember, clinically oriented, and could be readily incorporated into outcome studies of autologous breast reconstruction.

https://semanticscholar.org/paper/4661648b37b718ddd66b91b259f58480257c6ace

Annals of plastic surgery

Annals of Plastic Surgery

70

553–556

10.1097/SAP.0b013e31827ead1b

https://doi.org/10.1097/SAP.0b013e31827ead1b

23542852

2070380074

4c7e81bc81ae4344b28d56e03b6876901d8e54b8

Deoxyribonucleic Acid Relatedness Between Enterobacter cloacae and Enterobacter amnigenus sp. nov.

A deoxyribonucleic acid (DNA)-DNA hybridization study was carried out to determine the taxonomic position of a new group of enterobacters (group H3, Gavini et al. [Ann. Microbiol. (Inst. Pasteur) 127B:317-335, 1976]) previously studied by numerical taxonomy. The reassociation binding ratios with the group H3 strain ATCC 33072 ranged from 61 to 97%. With respect to DNA hybridization, this group, which represents a new species in the genus Enterobacter, Enterobacter amnigenus, is closely related (49 to 66%) to Enterobacter cloacae. A difference in genome size between E. amnigenus ATCC 33072 and E. cloacae Collection de l'Unite d'Ecotoxicologie Microbienne (CUETM) 77-120 was observed after reciprocal binding: The genome of ATCC 33072 was 24% larger. E. amnigenus was defined from phenotypic and genetic data. The type strain of E. amnigenus is CUETM 77-118 (ATCC 33072).

https://semanticscholar.org/paper/4c7e81bc81ae4344b28d56e03b6876901d8e54b8

International Journal of Systematic and Evolutionary Microbiology

31

35-42

10.1099/00207713-31-1-35

https://doi.org/10.1099/00207713-31-1-35

2123033945

f508f69aac15e9b99dfe4b87116f1ef6e36c37ad

Mortality associated with oral contraceptive use. Authors generalise their results to cohort that was never studied.

This is a letter that comments on the Royal College of Medicine s oral contraceptive (OC) study. The study s meta-analysis showed that women using OCs for 4 years or longer before their first term pregnancy had a 72% increased risk of developing breast cancer. But this analysis is based on a cohort of women from the 1960s and women in that decade were less likely than women of later decades to take OCs at such an early point in their reproductive lives. The study essentially examined a cohort of women who often took the pill after having at least one baby; its results therefore cannot be applied to women who often take OCs years before having their first child. Women taking pills before their first term pregnancy are more susceptible to developing breast cancer. Breast cells are most vulnerable to carcinogens before a woman has a baby as shown by extensive work on a rat model according to which virgin rats developed breast cancer more often than did rats that had been allowed to complete their first term pregnancy. The same phenomenon has been observed in humans.

https://semanticscholar.org/paper/f508f69aac15e9b99dfe4b87116f1ef6e36c37ad

BMJ

BMJ

319 7206

386-7

10.1136/BMJ.319.7206.386

https://doi.org/10.1136/BMJ.319.7206.386

10490327

2280764919

917703f9d7c981765d224ec48961c3af76589d44

Bovie Structure: Its Evolution and Regional Context

Bovie Structure, which marks the eastern limit of Upper Cretaceous strata in the Liard Basin, is interpreted from seismic and well data to be a product of two major stages of development: the first, crustal uplift and compression during the late-Carboniferous to early Permian; the second, horizontal convergence during the Laramide Orogeny. North of Trout Lake Fault zone the second phase involved a shallow decollement fault whereas south of Trout Lake Fault zone, Laramide stresses may have caused transpressional movement on the crustal scale fault and development of a ‘flower’ structure. Bovie Fault, which has long been considered to be extensional, is here interpreted to be convergent and a product of the earlier uplift. The structure is here divided into three zones—northern and central zones, which lie north of Trout Lake Fault zone, and a southern zone. The central zone, where Bovie Structure is most fully developed, contains Bovie anticline, which is seen at surface as a chain of three N–S striking ridges. This anticline is interpreted to consist of blocks of Carboniferous strata that first have been uplifted on a west-directed, steeply-dipping, crustal-scale thrust fault. Then, during the Laramide Orogeny, blocks of these Carboniferous strata were severed and carried eastward on the shallow detachment of the Bovie Lake Thrust. Bovie Fault rapidly diminishes northward across the northern zone until the remaining basement strain is transferred eastward to a second, smaller en echelon fault. In this zone, strata are interpreted to have responded to uplift of the eastern block with a combination of faulting and monoclinal folding. There is no evidence of a shallow Bovie Lake Thrust detachment in the northern zone. Southward, Bovie Structure turns abruptly southwest across the Trout Lake Fault zone, and the west-directed deep fault steps eastward in an en echelon manner. In the southern zone, there is little evidence for a shallow-detachment fault, and the second phase of development is interpreted to be one of transpressional reactivation of the west-directed, crustal-scale fault producing ‘flower’ structures. Uplift on Bovie Fault may have coincided with uplift of Celibeta High, which developed immediately east of Bovie Structure. Adoption of a two-stage contractional model has led to the identification of new conceptual plays on Bovie Structure.

https://semanticscholar.org/paper/917703f9d7c981765d224ec48961c3af76589d44

Bulletin of Canadian Petroleum Geology

52

302-324

10.2113/52.4.302

https://doi.org/10.2113/52.4.302

2154037163

f8e0a0b934c3844bba3c057d16f1abb189209140

Unveiling the Longitudinal Association between Short Sleep Duration and the Incidence of Obesity: the Penn State Cohort

Objective:Several epidemiologic, longitudinal studies have reported that short sleep duration is a risk factor for the incidence of obesity. However, the vast majority of these studies used self-reported measures of sleep duration and did not examine the role of objective short sleep duration, subjective sleep disturbances and emotional stress.Design:Longitudinal, population-based study.Subjects:We studied a random sample of 815 non-obese adults from the Penn State Cohort in the sleep laboratory for one night using polysomnography (PSG) and followed them up for a mean of 7.5 years. Subjective and objective measures of sleep as well as emotional stress were obtained at baseline. Obesity was defined as a body mass index (BMI) ⩾30 kg/ m-2.Results:The incidence of obesity was 15% and it was significantly higher in women and in individuals who reported sleep disturbances, shorter sleep duration and higher emotional stress. Significant mediating effects showed that individuals with subjective sleep disturbances who developed obesity reported the shortest sleep duration and the highest emotional stress, and that subjective sleep disturbances and emotional stress were independent predictors of incident obesity. Further analyses revealed that the association between short sleep duration, subjective sleep disturbances and emotional stress with incident obesity was stronger in young and middle-age adults. Objective short sleep duration was not associated with a significantly increased risk of incident obesity.Conclusion:Self-reported short sleep duration in non-obese individuals at risk of developing obesity is a surrogate marker of emotional stress and subjective sleep disturbances. Objective short sleep duration is not associated with a significant increased risk of incident obesity. The detection and treatment of sleep disturbances and emotional stress should become a target of our preventive strategies against obesity.

https://semanticscholar.org/paper/f8e0a0b934c3844bba3c057d16f1abb189209140

International Journal of Obesity

International journal of obesity (2005)

38

825 - 832

10.1038/ijo.2013.172

https://doi.org/10.1038/ijo.2013.172

24100421

2006620969

e8e7edd87f71214ff09fca4bbd136ec0305df6e1

Community-Based Multidisciplinary Computed Tomography Screening Program Improves Lung Cancer Survival.

BACKGROUND Lung cancer is the most common cause of cancer deaths in the United States. Overall survival is less than 20%, with the majority of patients presenting with advanced disease. The National Lung Screening Trial, performed mainly in academic medical centers, showed that cancer mortality can be reduced with computed tomography (CT) screening compared with chest radiography in high-risk patients. To determine whether this survival advantage can be duplicated in a community-based multidisciplinary thoracic oncology program, we initiated a CT scan screening program for lung cancer within an established health care system. METHODS In 2008, we launched a lung cancer CT screening program within the WellStar Health System (WHS) consisting of five hospitals, three health parks, 140 outpatient medical offices, and 12 imaging centers that provide care in a five-county area of approximately 1.4 million people in Metro-Atlanta. Screening criteria incorporated were the International Early Lung Cancer Action Program (2008 to 2010) and National Comprehensive Cancer Network guidelines (2011 to 2013) for moderate- and high-risk patients. RESULTS A total of 1,267 persons underwent CT lung cancer screening in WHS from 2008 through 2013; 53% were men, 87% were 50 years of age or older, and 83% were current or former smokers. Noncalcified indeterminate pulmonary nodules were found in 518 patients (41%). Thirty-six patients (2.8%) underwent a diagnostic procedure for positive findings on their CT scan; 30 proved to have cancer, 28 (2.2%) primary lung cancer and 2 metastatic cancer, and 6 had benign disease. Fourteen patients (50%) had their lung cancer discovered on their initial CT scan, 11 on subsequent scans associated with indeterminate pulmonary nodules growth and 3 patients who had a new indeterminate pulmonary nodules. Only 15 (54%) of these 28 patients would have qualified as a National Lung Screening Trial high-risk patient; 75% had stage I or II disease. Overall 5-year survival was 64% and 5-year cancer specific survival was 71% in the screened patients, whereas nonscreened lung cancer patients during that time in WHS had an overall survival of only 19% (p < 0.001). CONCLUSIONS A community-based multidisciplinary lung cancer screening program can improve survival of patients with lung cancer outside of a large multicenter study. This survival advantage was caused by a significant stage shift to earlier disease. Lung cancer CT screening may also benefit patients not meeting the National Lung Screening Trial criteria who are at moderate or high risk for lung cancer.

https://semanticscholar.org/paper/e8e7edd87f71214ff09fca4bbd136ec0305df6e1

The Annals of thoracic surgery

The Annals of thoracic surgery

101 5

1864-9

10.1016/j.athoracsur.2015.11.001

https://doi.org/10.1016/j.athoracsur.2015.11.001

26876342

2254068370

52da22182005692f2be688a2e1db0afbc2381cbb

Willow coppice plantations as wastewater treatment systems

Short rotation willow coppice (Salix) can be used as vegetation filter to treat industrial and municipal wastewater. In May 1998 a EU-FAIR project, "Biomass short rotation willow coppice fertilized with nutrient from municipal wastewater (BWCW)" was started to investigate the consequences to establish willow plantations to treat wastewater in some European countries with varying climatic conditions. The aims of this research project were to evaluate the positive effects of irrigation of willow-to­ energy plantations with wastewater, but also to find the negative consequences and to develop strategies to deal with them. The project comprises comparable pilot plantations located in four different climatic regions in the four European countries: France, Greece, Unite Kingdom and Sweden. In this paper the experiences from this EU research project BWCW, which will be finished off in 2002, are briefly described.

https://semanticscholar.org/paper/52da22182005692f2be688a2e1db0afbc2381cbb

233-238

10.15626/eco-tech.2001.027

https://doi.org/10.15626/eco-tech.2001.027

2982147018

dda2ce10b5da48331b4059d4fb8c40fd21c3b215

Estimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children

The Pacific Island nation of Samoa is marked by prevalent obesity and an increasing dependence on packaged foods likely to contain the endocrine disruptor bisphenol-A (BPA). We evaluated participant- and household-level characteristics associated with estimated dietary BPA exposure in Samoan mothers and their children and examined associations between dietary BPA exposure and body mass index (BMI) and abdominal circumference (AC). Dietary BPA exposure indices were estimated for 399 mother–child pairs by combining information from dietary questionnaires and relative concentrations of BPA measured in foods/beverages. We observed moderate to strong correlation between mother–child daily BPA indices (Spearman’s rho = 0.7, p < 0.0001). In mothers, we observed lower daily BPA indices in those who were less physically active (p = 0.0004) and living in homes with higher income (p = 0.00001). In children, we observed lower daily BPA indices in those living in homes with higher income (p = 0.0003) and following a less modern dietary pattern (p = 0.002), and higher daily BPA indices in those who were less physically active (p = 0.02). No significant associations were observed between daily BPA indices and BMI or AC. Despite this, the application of the daily BPA index identified factors associated with dietary BPA exposure and warrants further examination in Samoa and other understudied populations.

https://semanticscholar.org/paper/dda2ce10b5da48331b4059d4fb8c40fd21c3b215

Toxics

Toxics

8

10.3390/toxics8030067

https://doi.org/10.3390/toxics8030067

32887300

3082394366

b3f74d7eb8948679605ad3f7c3f94d1b31963363

Mouldable, biodegradable material

1. moldable biodegradable medical material, comprising a homopolymer based on epsilon-caprolactone having an average molecular weight ranging from 20000 g / mol <Mn <100,000 g / mol. ! 2. Material according to claim 1, characterized in that the polydispersity index of the polymer, measured on the basis of homopolymer of epsilon-caprolactone, is greater than 1.2. ! 3. Material according to claim 2, characterized in that the polydispersity index of the polymer, measured on the basis of homopolymer of epsilon-caprolactone, from about 1.5 to about 5! 4. Material according to any one of claims 1-3, characterized in that said average molecular weight of said homopolymer based on epsilon-caprolactone is in the range of 20,000 g / mol <Mn <80,000 g / mol, preferably between 25000 to 65000 g / mol, in particular from about 35,000 to 60,000 g / mol. ! 5. Material according to any one of claims 1-3, characterized in that said homopolymer based on epsilon caprolactone has an asymmetrical molecular weight distribution. ! 6. Material according to claim 5, characterized in that the fraction of low molecular weight polymer fraction exceeds that of high molecular weight polymer fraction. ! 7. Material according to any one of claims 1-3 or 6, characterized in that said polycaprolactone has a broad molecular weight distribution, wherein at least 5 mol.% Of polycaprolactone having a molecular weight of less than 25,000 g / mole and at least 5 mole .% polycaprolactone having a molecular weight greater than 60,000 g / mol. ! 8. Material according to any one of claims 1-3 or 6, characterized in that said material is capable of being formed by hand at a temperature of 70 ° C or less, in particular from 57 to 70 ° C. ! 9. Material according to any one of claims 1-3 or 6, characterized in that said mat

https://semanticscholar.org/paper/b3f74d7eb8948679605ad3f7c3f94d1b31963363

2773090259

be665f9cc844b8b24c7fa66e12f04b0145f5af46

Rfid tag of registration mark

FIELD: radio engineering. SUBSTANCE: invention relates to the field of radio engineering and is intended for the identification of objects (goods, products, structures, etc.) for various purposes and obtaining information about them, in particular RFID tags. Technical result is achieved in an RFID tag device made in the form of a short-circuited linear polarization antenna made of a conductive material having a section in the form of an elongated non-closed rectangle with two parallel current-conducting shelf surfaces differing in width and at least one lateral conductive surface-wall. Two shelves are electrically connected through one wall and through an RFID chip located between the shelves at a distance from the wall. EFFECT: technical result to which the invention is directed is the simplification of the design of the RFID tag, while maintaining efficiency. 18 cl, 3 dwg

https://semanticscholar.org/paper/be665f9cc844b8b24c7fa66e12f04b0145f5af46

2924352200

c0c08485cce8651527186d6bfc4f9b8632fcee60

Структура и биологическое действие потенциальных психотропных средств - Фосеназида и КАПАХ. Сравнительный анализ

Data of IR, UV, NMR (31P, 1H, 13C) spectra, x-ray crystallography, and quantum chemical calculations are presented for phosenazid and CAPAH molecules demonstrating psychotropic effects. In comparison with phosenazid, CAPAH exhibits a broader spectrum of neurotropic activity, which can be related to the presence of P1-O3 polar ester bond and therefore of higher reaction ability in metabolic processes.

https://semanticscholar.org/paper/c0c08485cce8651527186d6bfc4f9b8632fcee60

10.30906/0023-1134-2007-41-2-11-14

https://doi.org/10.30906/0023-1134-2007-41-2-11-14

1500138380

d5a36373a9a84172222851f73e4c779fd73e4c6f

On chip tunable micro ring resonator actuated by electrowetting.

We demonstrate a tunable on chip polymer waveguide micro ring resonator (MRR) device. The transmission spectrum and extinction ratio are controlled by electrowetting on dielectric (EWOD), via the application of voltage to a droplet. As a result the droplet covers a portion of the MRR waveguide and changes its effective refractive index. This method can be used for efficiently tuning a variety of on chip optical devices, as it offers high index contrast, electrical control and low power consumption.

https://semanticscholar.org/paper/d5a36373a9a84172222851f73e4c779fd73e4c6f

Optics express

Optics express

17 2

1116-25

10.1364/OE.17.001116

https://doi.org/10.1364/OE.17.001116

19158929

2157528327

3f840fbefa6dd5c6fda130ddb360932273701ad8

ON BIOLOGICAL MINE WATER TREATMENT TECHNOLOGY USING THE DEGRADATION PRODUCTS OF CELLULOSE 7

To comply to sound water management, pollution prevention of effluents is the key parameter. Mining as well as other industries produce large volumes of polluted waste water, which should be kept separate from clean water to prevent pollution of these clean water sources. In the situation that good housekeeping of water management is adhered to, water treatment can be applied. The studies presented in the previous chapters showed that the biological sulphate removal technology can be used to remove the salinity and acidity of mine water.

https://semanticscholar.org/paper/3f840fbefa6dd5c6fda130ddb360932273701ad8

e84074b0fc3e332a85b9c71b9ded83dda33a58df

A model of distributed storage

Discusses a recent development in psychological memory research, of which one of the end products is a model of distributed storage, as distinguished from the hitherto-prevailing concept of localiz ...

https://semanticscholar.org/paper/e84074b0fc3e332a85b9c71b9ded83dda33a58df

195

141-162

2524158046

515ff5adf31dda01661bbc3f7a6682f7efdc3202

Food Security and Nutrition Policies in India Support to FAPDA

A comprehensive work of the recent policy decisions has depicted some key areas where information is not available at research level. Therefore, in order to improve the design of the regional monitoring tool, it was identified the need to acquire an insight into the policy processes; to understand how policies are delivered, which factors contribute to implementation success and which others function as barriers to implementation.

https://semanticscholar.org/paper/515ff5adf31dda01661bbc3f7a6682f7efdc3202

122799271f8ee8ab11b02b8fbb9107d78cd83a4e

Homocysteine attenuates hemodynamic responses to nitric oxide in vivo.

Homocysteine is a significant but modifiable risk factor for vascular diseases. While several pathological processes may be involved, homocysteine can cause significant endothelial impairment and compromise vascular NO bioactivity. In the present study, we aimed to assess effects of homocysteine on NO-mediated hemodynamic responses in vivo. We created an acute hyperhomocysteinemia model (plasma homocysteine of 65-276 micromol/l) by continuous venous infusion of D,L-homocysteine to anaesthetized Sprague-Dawley rats. Vasodilators including NO donors: S-nitrosohomocysteine (SNOHcy), S-nitrosocysteine (SNOCys) and sodium nitroprusside (SNP), the endothelial NO synthase (eNOS) activator: acetylcholine (ACh), and calcium channel blocker: verapamil and nicardipine, were administered by one bolus injection to the homocysteinemic rats. While homocysteine infusion produced no change in the mean femoral arterial blood pressure, each of these vasodilators led to a rapid and substantial dose-dependent fall in blood pressure. Concurrent homocysteine infusion, however, attenuated the blood pressure lowering effects induced by NO donors (P<0.01), but not by the calcium channel blockers. Homocysteine inhibited not only the endothelial-derived NO as stimulated by ACh, but also the bioactivity of exogenously supplied NO by SNOHcy, SNOCys and SNP. Our findings indicate that homocysteine may have an effect on NO bioproduction and bioavailability. Vasodilating efficacy of commonly used NO donors such as nitroglycerine may be seriously compromised by hyperhomocysteinemia, which is common among ischemic heart disease patients.

https://semanticscholar.org/paper/122799271f8ee8ab11b02b8fbb9107d78cd83a4e

Atherosclerosis

Atherosclerosis

161 1

169-76

10.1016/S0021-9150(01)00654-2

https://doi.org/10.1016/S0021-9150%2801%2900654-2

11882329

2024933464

86e544ead7e44daac2d5976e3d01b03a687b3070

The Surgeon as a Consultant for Medical Device Manufacturers: What Do Our Patients Think?

Study Design. Patient survey. Objective. To evaluate patient perspective on surgeons as consultants for industry and medical device manufacturers. Summary of Background Data. Relationships between surgeons and medical device manufacturers are becoming increasingly common. Little is known, however, about how patients perceive these relationships. Methods. Patients in the waiting area of an orthopedic surgery clinic were given a simple 1-page, 8-question anonymous questionnaire. Their responses were tabulated and analyzed for 3 variables: gender, age, and education level. Results. A total of 245 patients completed the questionnaire. An overwhelming majority (94.3%) believed that surgeon-industry relationship is beneficial to patients, and a majority (66.5%) of patients thought that physicians should be compensated for this role. Women were more likely than men to want this relationship to be regulated by physicians instead of the government or hospitals. Patients older than 55 years were less likely to be in favor of physicians being compensated than younger patients. The more educated the patient, the less likely he/she was in favor of allowing physicians to regulate physician-industry relationship. Conclusion. Patients support surgeons in the role of consultants for industry. Gender, age, and education level influence the way that patients perceive this issue.

https://semanticscholar.org/paper/86e544ead7e44daac2d5976e3d01b03a687b3070

Spine

Spine

32

2616-2618

10.1097/BRS.0B013E318158CC3A

https://doi.org/10.1097/BRS.0B013E318158CC3A

17978663

2183753760

1fbddcd1ac57cfd859ef0a2e29276fae59611004

Party-state Realism: A Framework for Understanding China’s Approach to Foreign Policy

ABSTRACT The author puts forth an analytical framework called party-state realism for understanding how policy makers in the People’s Republic of China approach foreign policy. It has four defining characteristics. In order of importance, they are: putting the interests of the Communist Party at the core of China’s national interest calculation; and on this basis adopting an instrumentalist approach; adopting a party-centric nationalism; and adhering to a neoclassical realist assessment of the country’s place in the international system and its relative material power in advancing national interest. In this conception, the putting of the Chinese Communist Party’s interest at the core of national interest is a constant, not a variable, factor. This does not mean the changing international context and relative national power are irrelevant, just that they take secondary importance.

https://semanticscholar.org/paper/1fbddcd1ac57cfd859ef0a2e29276fae59611004

Journal of Contemporary China

29

304 - 318

10.1080/10670564.2019.1637562

https://doi.org/10.1080/10670564.2019.1637562

2953715580

58ac8afaae395ebcb3eba866ccb0b40c3ece096b

Colonial Planning and the Foundations of Eurocentric Diffusionism

The origin of development planning in Nigeria can be traced to the colonial period, specifically 1946, when the ten-year plan for development was launched. Prior to that time, two development plans had been launched in 1929 and 1940, for all the British colonies. The launching of development plans meant that Britain had abandoned the economic doctrine of laissez faire in favor of some form of state intervention in the economy. A number of factors gave rise to this change. Among them are the economic depression of 1929, the impact of World War II on the economies of European countries, and the increased demands for political and economic reforms in the colonies.

https://semanticscholar.org/paper/58ac8afaae395ebcb3eba866ccb0b40c3ece096b

47-72

10.1057/9781137286659_3

https://doi.org/10.1057/9781137286659_3

2478550530

504f60165753884cf4039dd95666354c0ce2740e

A frequent Aγ-persistence of fetal hemoglobin in northern Sardinia: its molecular basis and hematologic phenotype in heterozygotes and compound heterozygotes with β-thalassemia

SummaryA survey of hemoglobinopathies in northern Sardinia revealed a high frequency (0.3%) of carriers of a hematologic condition characterized by increased expression of fetal hemoglobin during adult life (hereditary persistence of fetal hemoglobin or HPFH). In spite of a normal hematologic phenotype, the heterozygous carriers for this condition display about 12% HbF, almost exclusively of the Aγ type; compound heterozygotes with β-thalassemia have 20%–26% HbF and run a very mild clinical course. The sequence analysis of the cloned Aγ gene linked to the HPFH determinant revealed the presence of a G→A substitution at position-117 of the Aγ- gene promoter; the same mutation occurs also in Greek HPFH, although associated with different restriction polymorphisms. Another hereditary condition characterized by increased HbF (α2Aγ2) level and a mild thalassemic phenotype in Sardinia is associated with the-196 C→T substitution in the Aγ-globin gene promoter (Sardinian δβ-thalassemia). Population studies using oligonucleotides complementary both to the-117 G→A and-196 C→T mutations and the corresponding normal sequences confirm the presence of these mutations only in HPFH and δβ-thalassemia chromosomes and exclude these changes being common DNA polymorphisms.

https://semanticscholar.org/paper/504f60165753884cf4039dd95666354c0ce2740e

Human Genetics

Human Genetics

79

13-17

10.1007/BF00291702

https://doi.org/10.1007/BF00291702

2046941639

0b714d7d9a2d1f2ffdfa05ead9d49516e73b7d89

Research on Evaluation of College Students' Environmental Literacy

By investigating and assessing college students' environmental literacy,major impact factors of influencing college students' environment literacy are obtained and then the countermeasures and suggestions for the environment education are put forward.

https://semanticscholar.org/paper/0b714d7d9a2d1f2ffdfa05ead9d49516e73b7d89

Ludong University Journal

2359541757

ab5c23d55c893c72fd8c30318a3d7667e3154cb3

Sedimentology, Petrology, and Reservoir Characteristics of Lower Strawn Sandstone, Bent Tree Field, Hardeman County, Texas: ABSTRACT

Reservoir sandstones of the lower Strawn Formation (early Middle Pennsylvanian) in the Bent Tree field of Hardeman County, Texas, are coarse to fine-grained, texturally submature arkoses. Cores show the sandstones to have been deposited in 1.5-4.5 m thick fining-upward successions of aggraded or prograded bar units. Each bar unit has a sharp erosional base overlain by cross-bedded, coarse-grained, conglomeratic sandstone, which, in turn, is overlain by medium to fine-grained, horizontally bedded or ripple-bedded sandstone. The coarse conglomeratic sandstones are interpreted to represent deposition in main channels of a braided fluvial system that were progressively filled by aggrading and prograding bars. The interbedded, finer grained, more immature sandstones appear to have been deposited in auxiliary channels or swales, or in proximal overbank settings. The detrital framework grain suite of the reservoir sandstones averages 47% quartz, 30% feldspars, 19% igneous rock fragments, and 4% sedimentary rock fragments. The source of these sands was a plutonic/cratonic igneous massif with minor exposures of older sedimentary strata, and was probably the ancestral Wichita Mountains. Diagenesis has significantly affected the petrographic and reservoir properties of the lower Strawn sandstones, primarily through the in-situ alteration of detrital feldspathic grains and by the precipitation of authigenic quartz overgrowths,more » chlorite clay, and carbonate cements.« less

https://semanticscholar.org/paper/ab5c23d55c893c72fd8c30318a3d7667e3154cb3

AAPG Bulletin

71

10.1306/94887974-1704-11D7-8645000102C1865D

https://doi.org/10.1306/94887974-1704-11D7-8645000102C1865D

2105302117

0e49ded0e790ae5fbd7cc4e0821462f148f6070b

A meta-analysis of tumor necrosis factor-alpha, interleukin-6, and interleukin-10 in preeclampsia.

Inflammation may play a major role in the pathogenesis of preeclampsia (PE). In this meta-analysis, we determined whether maternal polymorphisms and serum concentrations of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10) were associated with PE. All studies investigating the associations between PE and maternal polymorphisms of TNF-α-308G/A, IL-6-174G/C, and IL-10-1082A/G or serum concentrations of TNF-α, IL-6, and IL-10 were reviewed. We found that neither maternal TNF-α-308G/A (p=0.86, odds ratio [OR]=0.98, 95% confidence interval [CI], 0.76-1.25), IL-6 174G/C (p=0.14, OR=1.23, 95% CI, 0.93-1.61), nor IL-10-1082A/G (p=0.72, OR=1.07, 95% CI, 0.75-1.52) were associated with PE. On the other hand, maternal TNF-α (p<0.00001, weighted mean difference [WMD]=19.63 pg/ml, 95% CI, 18.54-20.72 pg/ml), IL-6 (p<0.00001, WMD=6.58 pg/ml, 95% CI, 5.49-7.67 pg/ml), and IL-10 (p=0.0005, WMD=19.30 pg/ml, 95% CI, 8.42-30.17 pg/ml) concentrations were significantly higher in PE patients versus controls. Our findings strengthen the clinical evidence that PE is accompanied by exaggerated inflammatory responses, but do not support TNF-α-308G/A, IL-6-174G/C, and IL-10-1082A/G as candidate susceptibility loci in PE.

https://semanticscholar.org/paper/0e49ded0e790ae5fbd7cc4e0821462f148f6070b

Cytokine

Cytokine

56 3

550-9

10.1016/j.cyto.2011.09.021

https://doi.org/10.1016/j.cyto.2011.09.021

22019000

2053216932

61e3b0523907f18f54a8fbd865854c4491095f69

Well log facies classification for improved regional exploration

Well log and rock sample data from fourteen offshore petroleum exploration wells have been successfully up-scaled and integrated using facies classification. Over 100 rock samples were categorised into six petrofacies classes based on their composition and texture. Cluster analysis was used to classify well log data into five electrofacies units, after careful conditioning and selection of input logs. The result is a direct link between well logs and rock samples. Electrofacies profiles clearly illustrate stratigraphic information previously hidden in the well logs. In addition, well log acoustic rock property relationships based on the new electrofacies classes are found to be better constrained than lithology-based models. Previous facies studies either have been applied at a field scale or have had conventional core for petrofacies calibration. In this paper, I illustrate how facies analysis can be successfully applied at a regional scale with only sidewall sample calibration. Particular attention was given to conditioning the cluster analysis input logs by removing all effects of fluid fill and mechanical compaction, which varied significantly across the study area. A lesson learned from the project was that it is easy to generate misleading results with cluster analysis, so care was taken to select only the most appropriate input logs, and to thoroughly quality control the output electrofacies.

https://semanticscholar.org/paper/61e3b0523907f18f54a8fbd865854c4491095f69

Exploration Geophysics

39

115 - 123

10.1071/EG08012

https://doi.org/10.1071/EG08012

2072612168

802cd0952050a6ebd8639cb3cc8fc53e33403de4

Simulation of Steam-Based Gasification Processes for Topping Combustion in the Biomass Air Turbine (BAT) Cycle

In this work, steam-based gasification is investigated as a technology for fuel gas production for topping combustion in a biomass air turbine (BAT) cycle. For different systems, based on flash or conventional pyrolysis, the characteristics of the product gas quality are studied. The gas composition and the heating value of the produced gas are simulated by changing the main system parameters such as the moisture content of the biomass, the operating temperature and the composition of the biomass.A model of the gasification process has been developed to evaluate each process. The model is based on mass conservation, the thermodynamic equilibrium of the water-gas-shift reaction and the methane yield during pyrolysis.A gasification system with flash pyrolysis is identified as a promising technology for fuel gas production for use in topping combustion. The major features of the system are: first, the system provides a gas with a heating value of near to 16 MJ/Nm3 and small amounts of nitrogen gas; second, the application of a water knock out unit eliminates the influence of the water content in the feedstock on the product gas quality; third, the gasification process can be conducted in a tubular reactor within the furnace of the BAT cycle. This reduces the number of reactors and keeps the costs low.Copyright © 2000 by ASME

https://semanticscholar.org/paper/802cd0952050a6ebd8639cb3cc8fc53e33403de4

10.1115/2000-GT-0021

https://doi.org/10.1115/2000-GT-0021

1965206357

10d42ad540b28b35ee24257b31cab498a339eda3

A Project to Examine the Use of Open Learning Techniques in COMADEM

Wolfson Maintenance is a consultancy group based in the University of Manchester. It specializes in condition based maintenance, designing and installing condition monitoring systems in a variety of industries, world-wide. Among its activities it runs a now well-established range of short courses for industry. The four courses offered are ‘Condition based Maintenance’, ‘Vibration Monitoring’, ‘Computers in Maintenanace’ and ‘Cost-Effective Maintenance’. It also mounts these courses, or similar courses packaged for a custtomer’s needs, in foreign venues. Recentil Wolfson courses have been presented in India and Thailand.

https://semanticscholar.org/paper/10d42ad540b28b35ee24257b31cab498a339eda3

10.1007/978-1-4684-8905-7_90

https://doi.org/10.1007/978-1-4684-8905-7_90

2233989985

ad69f063ef4474ecee8996f7a23a72e740670787

STUDY OF PHYSICO-CHEMICAL PROPERTIES OF FOOD GRAIN SORGHUM AND PRODUCT READY- TO-COOK MIX FOOD FROM SORGHUM

This study was conducted at Agricultural Engineering College and Research Institute, TNAU, Coimbatore. It was aimed at investigating en☺gineering properties of pearled sorghum grain ((Sorghum bicolor L. Moench) viz., moisture content (db), colour, water activity, bulk density, porosity, true density, sphericity, geometric mean diameter, hardness, angle of repose, coefficient of friction(using mild steel (MS) and stainless steel (SS) sheet) and thousand kernel weight. Some important physical properties of Ready-To-Cook Mix from sorghum(sorghum grits of three size Mix) like bulk density, porosity, true density, angle of repose and coefficient of friction (using MS and SS sheet) was also evaluated. Biochemical analysis of sample was conducted to study the key properties such as carbohydrates, protein, fat, crude fibre and ash content to know nutritional constituencies of product and its suitability for human consumption.

https://semanticscholar.org/paper/ad69f063ef4474ecee8996f7a23a72e740670787

2186264793

f92904a28521af946b23a11b483a834f2f1c069f

Financial Markets Development, Business Cycles, and Bank Risk in South America

In this paper, we examine whether banking crises or business cycles affect the influence of financial markets development on bank risk in a sample of 37 publicly listed commercial banks in seven South American countries over a 22-year period between 1991 and 2012. Banking crises in this region offer a natural setting in which the impact of financial markets development on bank risk is examined. We find that financial markets development improves banks’ capitalization ratio and reduces their exposure to non-traditional banking activities, suggesting that financial markets development on average reduces bank risk. In addition, banking crises and business cycles appear to moderate the impact of financial markets development on bank risk. In the aftermath of banking crises, banks appear to concentrate more on their core traditional banking activities.

https://semanticscholar.org/paper/f92904a28521af946b23a11b483a834f2f1c069f

Financial Crises eJournal

10.2139/ssrn.2617974

https://doi.org/10.2139/ssrn.2617974

1957706328

f43eb16c4f77a83e28cc08404e3d0837b772b7ec

The boundary fluctuation theory of transport coefficients in the linear-response limit.

In this paper we present, for the first time, a linear-response theory of transport coefficients-shear viscosity and thermal conductivity-involving thermal, as opposed to mechanical, fields. The theory involves the explicit treatment of the boundaries and the constraints that are applied to them. Expressions for the shear viscosity and thermal conductivity are obtained in terms of the fluctuations at the boundaries of the variable conjugate to that which is constrained. We explain how the choice of ensemble, as defined by the boundary constraints, determines the form in which the transport coefficients are evaluated.

https://semanticscholar.org/paper/f43eb16c4f77a83e28cc08404e3d0837b772b7ec

The Journal of chemical physics

The Journal of chemical physics

124 1

14103

10.1063/1.2140274

https://doi.org/10.1063/1.2140274

16409020

2053888022

2f51f9cbca45942da6e651e13918078ab8632b67

MEASURING THE PROCESS EFFICIENCY OF CONTROLLED WELDING PROCESSES

This The process efficiency in Seem and Arc Welding is a crucial input to Mathematical models of the process and requires the use of an accurate welding calorimeter. In this paper we compare a liquid nitrogen calorimeter with an insulated box calorimeter for measuring the process efficiency of Fronius CMT, Lincoln STT and Rapid Arc, Kemppi FastRoot and standard pulsed GMAW. All the controlled dip transfer processes had a process efficiency of around 85% when measured with the liquid nitrogen calorimeter.

https://semanticscholar.org/paper/2f51f9cbca45942da6e651e13918078ab8632b67

2184807766

6049966a998923ad356f7c4499144023ca013491

Prevention of Obesity and Hyperlipidemia by Heptamethoxyflavone in High-fat Diet-induced Rats.

Polymethoxyflavones (PMFs) have been shown to prevent obesity, ameliorate type 2 diabetes, and regulate lipid metabolism in vitro and in vivo. However, little is known about the contribution of 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF) to prevent obesity and regulate lipid metabolism in vivo. We aimed to investigate the potential efficacy of HMF on preventing obesity and hyperlipidemia in rats fed a high-fat diet (HFD) and its underlying mechanisms. Male Sprague-Dawley rats were fed a normal diet or an HFD with or without HMF (0.02%, 0.04% and 0.08%, w/w) for 6 weeks. The supplementation of HMF not only significantly decreased body weight gain (HFD, 336.50 ± 18.84 g; LHMF, 309.43 ± 20.74 g; MHMF, 296.83 ± 13.88 g; HHMF, 265.71 ± 19.09 g; respectively, p < 0.05) and adipose tissues weight ( p < 0.05), but also markedly lowered serum levels of total cholesterol, triacylglycerol, and low-density lipoprotein cholesterol ( p < 0.05) in the sixth week in a dose-dependent manner compared with the HFD group. HMF also significantly alleviated hepatic steatosis in the liver (liver weight g/100 g body weight of HFD, 4.86 ± 0.11%; LHMF, 4.02 ± 0.33%; MHMF, 4.05 ± 0.31%; HHMF, 3.72 ± 0.34%; respectively, p < 0.05). Furthermore, transcriptome analysis and real-time quantitative RT-PCR demonstrated that HMF supplementation markedly downregulated hepatic genes related to adipogenesis transcription and inflammatory responses, and significantly upregulated genes related to fatty acid oxidation and energy expenditure. These results indicated that HMF could effectively prevent obesity and hyperlipidemia by regulation of the expression of lipid metabolism-related and inflammatory response-related genes.

https://semanticscholar.org/paper/6049966a998923ad356f7c4499144023ca013491

Journal of agricultural and food chemistry

Journal of agricultural and food chemistry

67 9

2476-2489

10.1021/acs.jafc.8b05632

https://doi.org/10.1021/acs.jafc.8b05632

30740980

2914237081

32722e3b9264a4ca7bc540cae3d6a0efdaeeb838

Coenzyme-Catalyzed Electro-RAFT Polymerization

Here we report an electrochemically switchable reversible addition–fragmentation chain transfer polymerization (eRAFT). A new family of biochemical coenzymes are discovered that can be used as highly efficient electroredox catalysts to mediate this polymerization. The oxidation of coenzyme, nicotinamide adenine dinucleotide (NADH), can promote the reduction of a chain transfer agent, triggering generation and propagation of polymer radicals. External potential can activate the reduction of the NAD+ oxidized state and pause the propagation. Tuning the applied potential to reversibly switch the catalyst between its reduced and oxidized states can toggle the polymerization between ON and OFF states. This new strategy is universal to a broad scope of monomers, and ppm-level coenzymes result in the desirable polymer structures with targeted molecular weight, dispersity, and excellent chain-end fidelity. We envisage that the bioorganic-based catalysts would open new directions of organocatalyzed electro-control...

https://semanticscholar.org/paper/32722e3b9264a4ca7bc540cae3d6a0efdaeeb838

ACS Macro Letters

6

1337-1341

10.1021/ACSMACROLETT.7B00886

https://doi.org/10.1021/ACSMACROLETT.7B00886

2768957725

60d784aadad03ca5b78e332c1a3452ef365698b1

Disruption of cytoskeleton by methylmercury in cultured CHO cells.

The effect of methylmercury (MM) on three main cytoskeletal components [i.e. microtubules (MT), microfilaments (MF) and intermediate filaments (IF)] and on specific biochemical parameters (i.e. glutathione transferase (GST), glutathione reductase (RED), glutathione peroxidase (GSH-Px), glyoxalase 1 (GLY 1) and total -SH groups (TSH) of the cytosolic fraction) was studied in cultured Chinese hamster ovary (CHO) cells. The experiments were conducted with increasing doses of MM (i.e. 1, 4 and 8 mum), using an exposure time of 16 hr; and with a fixed dose of MM (2 mum), using increasing exposure periods (i.e. 0-24 hr). The morphological changes observed by immunofluorescence seemed to indicate that MF were damaged as much as (if not more than) MT after 16 hr of exposure to 4 mum-MM. At a concentration of 1 mum, MM only affected MF. The time-course experiments revealed that IF as well as MF and MT were severely disorganized after 3 and 6 hr of incubation in the presence of 2 mum-MM. However, an obvious reorganization was observed after 24 hr of exposure. In experiments using increasing MM doses, changes in the enzymatic activities were less noticeable than those observed in the morphology; only a modest decrease in TSH and RED activities (<30%) was recorded at the highest dose of MM used (i.e. 8 mum). In contrast, increasing the time of exposure to MM induced changes in both the cytoskeletal structures and the biochemical parameters: the lowest RED activity and TSH were observed after 3-6 hr exposure; control values were obtained after an exposure period of 24 hr. Ultrastructural observations on cells treated with increasing doses of MM showed changes in plasmamembrane profile, cytoskeleton organization and mitochondrion structure. The results confirm that MM causes non-specific damage to CHO cells and suggest that a functional interaction may exist between GSH-dependent enzymes and cytoskeletal structures.

https://semanticscholar.org/paper/60d784aadad03ca5b78e332c1a3452ef365698b1

Toxicology in vitro : an international journal published in association with BIBRA

Toxicology in vitro : an international journal published in association with BIBRA

6 1

61-70

10.1016/0887-2333(92)90086-7

https://doi.org/10.1016/0887-2333%2892%2990086-7

20732093

2014938069

9126e42c707fdaa55e41ecea3db4bccaf50ceeba

LE PRINCIPE D'INTÉGRITÉ COMME DROIT NATUREL UNE INTERPRÉTATION PHILOSOPHIQUE DU STATUT ONTOLOGIQUE D'ENFANTS EN ÉTAT DE MORT CÉRÉBRALE

Japanese philosophers encountered “bioethics” in the late 1980s. Young scholars in that period started to read bioethics literatures, and translated important works written in English. However, some scholars, including me, were very frustrated with their discussion because it was heavily influenced by analytic philosophy, and seemed to lack the examination of realities ordinary people would face in their everyday lives. Since then, I have tried to create a new philosophical approach that could grasp bioethical issues from various angles, which had been sometimes overlooked in the field of academic bioethics. For example, concerning the issue of brain death, I have stressed the importance of “human relationship oriented approach to brain death.” I gave the explanation why family members sometimes felt that a beloved one was still alive in the state of brain death, using such concepts as “intercorporality” and “presentation.” This finding made me think that the “personhood argument,” which has been widely accepted in the bioethics community, was theoretically flawed, that is to say, it did not explain the multi-layered reality of the concept of a human person. Then I gradually began to realize that the human relationship oriented approach should include, theoretically speaking, the relationship between the discussed subject and the researcher him/herself. It became clear when I discuss abortion from the perspective of feminist bioethics. Morioka, the author of this paper, is a male. The more I read feminist literatures, the more I came to think that what was really needed was not to read feminist arguments but to think abortion from my own point of view as a male who might force women to abort their fetuses. This realization led me to the development of a new approach, a “life studies approach” to bioethics. In this paper, I will try to illustrate why such an approach was required when dealing with bioethical issues, and to illustrate what kind of influence it could have on future philosophy and ethics. The life studies approach has created two important concepts, namely, “fundamental sense of security” and “painless civilization.” The fundamental sense of security is the feeling that one’s existence is welcomed unconditionally, and painless civilization is a driving force that tends to erode this kind of feeling of security, both of which are extremely helpful to analyze the negative aspects of contemporary society with advanced science and technology. And finally, I would like to discuss a “philosophy of life” project I have proposed in recent years. It seems to me that it is time to cast a new light on questions of philosophy of life, such as “What is life and death?,” “What is the meaning of life?,” and “What is the difference between human life and the life of non-human creatures?” against the background of contemporary bioethics and environmental ethics. And I would like to discuss the significance and magnitude the philosophy of life project could have not only for academicians but also ordinary citizens who are overwhelmed by the “meaning of life” questions and anxieties arising from our complicated, materialistic society

https://semanticscholar.org/paper/9126e42c707fdaa55e41ecea3db4bccaf50ceeba

227

140

10.3917/DIO.227.0140

https://doi.org/10.3917/DIO.227.0140

2325528688

c79ee2fe61aa6316ddab900a33061c488c6c3252

Loughborough University Institutional Repository Diffusivity variation in electromigration failure

Electromigration driven void dynamics plays an important role in the reliability of copper interconnects; a proper understanding of which is made more difficult due to local variations in line microstructure. In simulations, the parameter which best incorporates these variations is the effective atomic diffusivity Deff which is sensitive to grain size and orientation, interface layer thickness, etc. We examine a number of experimental results and conclude that, to explain observations using current theoretical models, Deff values must vary significantly along the interconnect, and that such variations are enough to yield encouraging simulations of resistance variations under bidirectional stress.

https://semanticscholar.org/paper/c79ee2fe61aa6316ddab900a33061c488c6c3252

57207632c69165e1d17ab3d0f67da30f1c21a35b

Bluff body flow : wake behavior behind a heated circular cylindeer

The main objective of this thesis is to get a better understanding of the wake behavior of a circular cylinder when the cylinder is heated. To do so the influence of viscosity on the wake generation is investigated. Results are gained from calculations performed with a DNS CFD program. Also the possibility to manipulate the wake is investigated. The setup is for a case at relatively low speeds, the Reynolds number is set to 200 and the Mach number to 0.2. As a benchmark, flows with Reynolds numbers varying from 50 - 500 over a non-heated cylinder have been calculated, and the differences are investigated. These differences are then compared to the changes of the wake when the cylinder is heated in the flow at Re=200 and Ma=0.2. Calculations have been performed for two different fluids, water and air respectively. With the gained insight a practical setup at the UCLA can be used for a larger variety of flow conditions

https://semanticscholar.org/paper/57207632c69165e1d17ab3d0f67da30f1c21a35b

158976403

d43f4bf3d7c514354c909621405701b83b46298f

The relationship between quality of work life and human resource productivity in knowledge workers

Introduction: Health care systems depend critically on the size, skill, and commitment of the health workforce. Therefore, researchers have a close observation on the subjects which leads to an increase in the productivity of human resources. This study aims at determining the relationship between the quality of work life and the productivity of knowledge workers of the central field of Shiraz University of Medical Sciences, in order to determine the factors effective in the quality of their working life. Method: This cross-sectional study was conducted on 300 individuals selected by stratified random sampling method. On 761 knowledge workers of the central field of Shiraz University of Medical Sciences by using Timossi questionnaire of Quality of Work Life and Knowledge Worker Productivity Assessment questionnaire of Antikainen, during May and June 2011. The collected data were recorded by SPSS version 15 software and then it underwent statistical analysis using Pearson correlation. The P value level for statistical significance was set at 0.05.Results: In general, 50% of the knowledge workers were dissatisfied about their quality of work life, and the other 50% had little satisfaction. 18% of the staff were in an unfavorable condition and 82% had a poor productivity. Also, the quality of work life had a positively significant relationship with the productivity of human resources (r=0.568; P>0.001).Conclusion: Most of the knowledge workers in the central field of Shiraz University of Medical Sciences had low productivity and quality of work life. Considering the relationship between the two variables, taking measures to improve the quality of work life can lead to more creative and profound planning in presenting services and, as a result, improving the productivity of the knowledge workers.Keywords: Quality of work life, Human resource productivity, Knowledge workers

https://semanticscholar.org/paper/d43f4bf3d7c514354c909621405701b83b46298f

1

59-65

1940628143

f998659e08c7951bcdb2d6bba13381085eb72c0f

A HARDWARE AND SOFTWARE OVERVIEW ON THE NEW BTF TRANS- VERSE PROFILE MONITOR

In the last 11 years, the Beam-Test Facility (BTF) of the DAFNE accelerator complex, in the Frascati laboratory, has gained an important role in the EU infrastructures devoted to the development of particle detectors. The facility can provide electrons and positrons, tuning at runtime different beam parameters: energy (from about 50 MeV up to 750 MeV for eand 540 MeV for e+), intensity (from single particle up to 1010/bunch) and pulse length (in the range 1.5–40 ns). The bunch delivery rate is up to 49 Hz (depending on the operations of the DAFNE collider) and the beam spot and divergence can be adjusted, down to sub-mm sizes and 2 mrad (downstream of the vacuum beam-pipe exit window), matching the user needs. In this paper we describe the new implementation of the secondary BTF beam transverse monitor systems based on ADVACAM FitPIX® Kit detectors, operating in bus synchronization mode externally timed to the BTF beam. Our software layout includes a data producer, a live-data display consumer, and a MEMCACHED caching server. This configuration offers to BTF users a fast and easy approach to the transverse diagnostics data using TCP/IP calls to MEMCACHED, with a user-friendly software integration of virtually any DAQ system. The possibility of sharing mixed data structures (user-generated and BTF diagnostics) allows to completely avoid the complexity of hardware synchronization of different DAQ systems. THE DAΦNE BEAM TEST FACILITY (BTF) The BTF (Beam Test Facility) is part of the DAΦNE accelerator complex: it is composed of a transfer line driven by a pulsed magnet allowing the diversion of electrons or positrons, usually injected into to the DAΦNE damping ring, from the high intensity LINAC towards a fully equipped experimental hall. The facility can provide runtime tuneable electrons and positrons beams in a defined range of different parameters. The beam energy can be selected from about 50 MeV up to 750 MeV, for electrons, and 540 MeV for positrons. In dedicated mode (DAΦNE off), the beam pulse length can also be adjusted in 0.5 steps from 1.5 to 40 ns. The delivery rate is depending on the DAΦNE injection frequency (25 or 50 Hz) with a duty cycle also changing according to the DAΦNE injection status, up to 49 bunches/s. Two major modes of operations are possible, depending on the user needs: high and low intensity. In the high intensity mode the LINAC beam is directly steered in the BTF hall with a fixed energy (i.e. the LINAC one, fixed to 510 MeV during the collider operations) and with reduced capability in multiplicity selection (typically from 1010 down to 104 particles/bunch). In the low intensity mode a step Copper target, allowing the selection of three different radiation lengths (1.7, 2 or 2.3 X0), is inserted in the first portion of the BTF line for intercepting the beam: this produces a secondary beam with a continuous full-span energy (from LINAC energy down to 50 MeV) and multiplicity (down to single particle/bunch), according to the setting of a 43° selecting dipole and of two sets of horizontal and vertical collimators. The typical momentum band is well below 1% down to 50 MeV. A pulsed dipole magnet at the end of the LINAC allows alternating the beam between the DAΦNE damping ring and the test beam area, thus keeping a pretty high BTF duty cycle, assuring an average of at least 20 bunches/s during the injection in DAΦNE, when BTF operates in the low intensity regime. BTF PIXEL DETECTOR LAYOUT A general overview of the BTF detectors and a description of the related software can be found here [1, 2]. Detector beam-testing generally require a fast transverse beam imaging during runtime, with some pre-analysis capability and, as in the BTF case, with a stable, reproducible and well-known response in the full range of energy, multiplicity and transverse dimensions of the particle beam. In addition, taking into account the BTF heavy work-cycle (beam is generally allocated in one-week slots for a minimum of 25 up to 40 weeks/years, including BTF-dedicated shifts), the equipment has to be reliable, robust, and with an easy maintenance, in order to guarantee full readiness and high-availability for the users purposes. For the same reasons, the related low-level software has to comply with these demanding requirements: not only very high reliability, but also easy and efficient integration in the vast variety of user acquisition software codes. Concerning the high level software, we decided to have the possibility of a fully featured runtime data display using LabVIEW®. ADVACAM Silicon Pixel Detector In [1], we described the setup based on a MEDIPIX-like silicon pixel detector with ADVACAM FitPIX® Kit electronics, at first made routinely available to the users via the basic version of the provided software, PIXET®, implemented in the BTF timing and virtual machine sub-systems. This solution well accomplished data acquisition and data-logging tasks (customizable thanks to the possibility of python scripting), but we decided to move to a completely custom low level C-code to better match our facility ___________________________________________ †luca.foggetta@lnf.infn.it WEPG73 Proceedings of IBIC2016, Barcelona, Spain ISBN 978-3-95450-177-9 818 C op yr ig ht © 20 16 C C -B Y3. 0 an d by th e re sp ec tiv e au th or s Transverse Profile Monitors and user requirements of a run-time data retrieval and handling of the pixel data (sharing with heterogeneous acquisition and storage systems, data display, basic analysis and beam parameters extraction, etc.), capable of sustaining the full BTF repetition rate of 50 Hz. FitPIX is a Medipix/Timepix detector interface with readout speed of up to 90 frames per second for single detector layer, in particular our Timepix sensors have a square pixel of 55 μm side arranged in a 256×256 pixels matrix (side length about 15 mm) for a square sensitive area of about 2 cm2 and 300 μm of thickness. Multiple FitPIX devices can be used essentially for two purposes: forming a particle tracker or as multilayer imager. The integration of a multiple sensors can be done essentially with two methods: the first by attaching up to four Timepix detector layers (single gap of 3.6mm, maximum overall longitudinal length about 20mm); the second possibility, allowing an arbitrary gap between each sensor plane, is to connect more FitPIX devices in daisy chain, with an external bus for the synchronization and master/slave trigger signals. In both cases the electronics communicates with a computer via the USB 2.0 interface for configuration, control and data retrieval [3]. BTF FITPIX Detector Usage In order to have a completely arbitrary access to live data at the maximum frame-rate within the BTF duty cycle, we have implemented software architecture with a typical producer-consumer layout, implementing data caching on MEMCACHED(MC) server, to allow more than one different consumers at the same time (see below). This has been possible exploiting all the available programming solutions: starting with the python scripting capability of the provided software kit, down to low-level programming, which required some interaction with ADVACAM for a full exploitation of the Linux libraries. We have a fully working version of the software for the single FitPIX, the multidetector-single FitPIX, and more FitPIX devices in daisy chain. As a by-product, the same software architecture allowed us to have a similar implementation for a GEMPIX tracker [4], a four sensors detector with a software configuration similar to the four stacked layers in a single FitPIX. We initially started with profiling a single FitPIX in different proprietary software configurations (bundle PIXETPRO software with Python scripting capabilities) with external (50Hz) trigger, and single frame acquisition vs. multiple frame acquisition with acquisition repetitions. As long as the fired pixel multiplicity is less than 10 (e.g. in a cosmic run, or in the single-particle BTF beam regime, defined as low data regime), the amount of data stays well below one MTU. In the following Tab. 1 we summarize the PIXETPRO software timing profile with a BTF external trigger at 50Hz: timing responses are reported for both Windows7 (PIXET WIN) running on a dual core, 3GHz, 8GB RAM PC with MC calls. In the PIXETPRO software, we explored the possibility to export data via Python scripting in the Windows environment (PIXET WIN Py) using the python-memcached package. In our test conditions, we were able to cope with the continuous frame rate only in multiple frame mode readout, but without actually sending the data on MC (again, via Python scripting). In those tests, we have also measured a minimum baseline ~26ms delay before getting the first frame in each new acquisition due to DAC setup, thus degrading a little the maximum achievable rate in multi-frame acquisition during repetitions, as clearly visible in the values for single vs multiple frame acquisitions in Tab. 1. Due to the not negligible impact of this delay and in order to accomplish full rate data retrieval we had then to develop custom software with runtime extraction of each frame in multi-frame acquisition. Table 1: Time Profiling PIXET Software with Python Scripting on MC CODE (OS) MC Trigger Trigger Type Frame time [s] N frames N Rep Acq. Rate [Hz] PIXET(WIN) Py Y 50 Hz HW_Start 1.00E-05 1000 10 23.26 PIXET(WIN) Py Y 50 Hz HW_Start 1.00E-05 1 1000 24.61 PIXET(WIN) Py N 50 Hz HW_Start 1.00E-05 1000 10 48.48 PIXET(WIN) Py N 50 Hz HW_Start 1.00E-05 1 1000 24.90 PRODUCER SOFTWARE LAYOUT We achieved the best performance of our code by using C/C++ compiled code in an Ubuntu 14.04LTS environment, using the multiple frame acquisition, and by interfacing to a modified API library, in strong collaboration with the ADVACAM software engineers. For a single FitPIX, a multiple frame acquisition is managed by a single thread handling the FitPIX USB interrupt. After each triggered frame a (intra-thread)

https://semanticscholar.org/paper/f998659e08c7951bcdb2d6bba13381085eb72c0f

fb9364ea651ba68d7a4db4c264cc1413960ade2c

Development of a Novel 30 kV Solid-state Switch for Damped Oscillating Voltage Testing System

This paper describes the design and development of a novel semiconductor-based solid-state switch for damped oscillating voltage test system. The proposed switch is configured as two identical series-connected switch stacks, each of which comprising 10 series-connected IGBT function units. Each unit consists of one IGBT, a gate driver, and an auxiliary voltage sharing circuit. A single switch stack can block 20 kV-rated high voltage, and two stacks in series are proven applicable to 30 kV-rated high voltage. The turn-on speed of the switch is approximately 250 ns. A flyback topology-based power supply system with a front-end power factor correction is built for the drive circuit by loosely inductively coupling each unit with a ferrite core to the primary side of a power generator to obtain the advantages of galvanic isolation and compact size. After the simulation, measurement, and estimation of the parasitic effect on the gate driver, a prototype is assembled and tested under different operating regimes. Experimental results are presented to demonstrate the performance of the developed prototype.

https://semanticscholar.org/paper/fb9364ea651ba68d7a4db4c264cc1413960ade2c

Journal of Power Electronics

16

786-797

10.6113/JPE.2016.16.2.786

https://doi.org/10.6113/JPE.2016.16.2.786

2346938545

548dd758dd76e100cfa108503c38efb20e298aaf

Gluon Schwinger-Dyson equation in the PT-BFM scheme

Schwinger-Dyson equations provide an appropriate framework for tackling non-perturbative QCD phenomena requiring a continuum treatment. However, an inadequate truncation of this tower of integral equations can compromise the symmetries underlying the theory in question. The synthesis of the Pinch Technique and the Background Field method provides a framework where it is possible to devise a self-consistent truncation scheme, exploiting the Ward identities satisfied by the effective Green's functions that emerge. In this work we review how this truncation scheme is implemented, and show that the new series of dressed diagrams for the background gluon propagator organizes itself in characteristic subsets that are individually transverse. In addition, we discuss how the Background Quantum identity connects the background gluon propagator with the conventional one, computed in the lattice simulations.

https://semanticscholar.org/paper/548dd758dd76e100cfa108503c38efb20e298aaf

706

052004

10.1088/1742-6596/706/5/052004

https://doi.org/10.1088/1742-6596%2F706%2F5%2F052004

2406458312

f12be49612ba77801fbafa15bd6eb1a870c79db9

Exhibitions about Human Communication in interactive science museums

PURPOSE: To investigate the existence of exhibitions and displays on topics related to Human Communication in national and international interactive science museums, and analyze the content to determine what are the issues related to Speech-Language Pathology and Audiology discussed in the museums. METHODS: Website analysis of 40 international science and/or technology museums and 20 national museums to identify exhibitions or displays related to the theme "Human Communication". RESULTS: Most of the researched museums have exhibitions or displays related to Human Communication. Among the national museums only four have an entire exhibition related to the topic, and among the international museums, thirteen exhibitions were found. The number of international exhibitions is greater than the number identified in national museums, and the quality of the material also varies. The primarily discussed topic in museums is acoustics, followed by message reception by hearing sense. Most museums do not approach the topics of message production, language, and voice anatomy and physiology. CONCLUSION: Science museums address basic sciences and, for this reason, acoustics is much explored. Many exhibits were found on topics related to Human Communication that allow individuals to learn about how the human body works, arousing curiosity about the subject. Because museums are institutions of science communication and informal education that contribute to the population's scientific literacy, Speech-Language Pathology and Audiology can take advantage of these spaces to disseminate research and knowledge about Human Communication.

https://semanticscholar.org/paper/f12be49612ba77801fbafa15bd6eb1a870c79db9

Revista Da Sociedade Brasileira De Fonoaudiologia

17

78-84

10.1590/S1516-80342012000100015

https://doi.org/10.1590/S1516-80342012000100015

2969711446

7e9a334e4ed77ff11fdf5f9aa9df0d08468464fb

Unification of the Kirchhoff approximation and the method of moment for optical wave scattering from the lossy dielectric Gaussian random rough surface

The optical wave scattering from one-dimensional (1D) lossy dielectric Gaussian random rough surface is studied. The tapered incident wave is introduced into the classical Kirchhoff approximation (KA), and the shadowing effect is also taken into account to make the KA results have a high accuracy. The definition of the bistatic scattering coefficient of the modified KA and the method of moment (MOM) are unified. The characteristics of the optical wave scattering from the lossy dielectric Gaussian random rough surface of different parameters are analyzed by implementing MOM.

https://semanticscholar.org/paper/7e9a334e4ed77ff11fdf5f9aa9df0d08468464fb

Chinese Optics Letters

7

259-262

10.3788/COL20090703.0259

https://doi.org/10.3788/COL20090703.0259

1972429661

600f622bbf2076724c22ab0eb6cd6886b20f867a

Evaluation of Metal Contamination in Freshly Deposited Sediment of Hugli Estuary, India

Metal contamination in sediment of Hugli estuarine system has often been assessed using datasets that provide dramatic over – or underestimate of actual status of sediment contamination due to lack of stipulated guidelines for collecting sediment with respect to grain sizes. This study has been undertaken to present how the level of metal contamination in sediment can be evaluated. The analytical results focus spatial and temporal conditions of metals in 200- mm and 63-mm sediment fractions. To better elucidate actual degree of metal pollution, contamination sources, and geochemical processes; statistical analysis are employed to intensive datasets collected from Hugli estuary that discharges into the largest alluvial fan in the world. Multivariate analysis including hierarchical cluster analysis clearly identified influence of anthropogenic and natural activities on metal contamination and geochemical processes controlling level of metal contamination in sediment of Hugli estuary. Normalization of Al indicated relatively high enrichment factors for Pb, Ni, Cu, Co, Cd, Cr and Fe suggesting contamination of these metals due to anthropogenic activities. Strong seasonal change, variable tidal energy level and irregular estuarine geometry in the study area played crucial role in governing metal concentration in freshly deposited sediment. This paper sheds some lights on necessity of refining existing monitoring practice and its importance in estuarine environment management.

https://semanticscholar.org/paper/600f622bbf2076724c22ab0eb6cd6886b20f867a

Archives of Applied Science Research

4

1155-1168

2600988236

b78cec77dba72e2839895597219e77de9c20c09e

Association of glomerular C4d deposition with morphologic variables of Oxford classification in IgA nephropathy patients; a preliminary study

Abstract Introduction: IgA nephropathy (IgAN) is known as the most prevalent primary chronic glomerulopathy. Hence, it is of critical importance to identify the aggravating factors impacting the disease progress, and to predict disease-specific therapy. Objectives: The aim of our investigation was to determine whether C4d deposits in glomeruli had any correlation with various immunopathologic variables of Oxford classification in IgAN. Patients and Methods: The characterization of IgAN requires the presence of diffuse and global IgA deposits which were graded ≥2+ with weak C1q deposition. C4d immunohistochemical (IHC) staining was conducted retrospectively on 29 renal biopsies of patients with IgAN, who were selected randomly from all biopsies. C4d IHC staining was performed on 3-μm deparaffinized and rehydrated sections of formaldehyde-fixed, paraffin-embedded (FFPE) renal tissues. Results: In this study, a significant correlation of C4d deposits with interstitial fibrosis/tubular atrophy (IFTA; T) (r=0.58, P=0.001) was obsereved. An analysis regarding the association of C4d deposits with other deposited antibodies and complement fragments showed that only C3 had a significant negative correlation with C4d deposits ( r=-0.42, P=0.02). Conclusion: The results show that C4d deposits correlate with IFTA or T variable of Oxford classification of IgAN. There is no significant correlation of C4d deposits with other morphological variables of Oxford classification. C4d deposits showed a negative correlation with C3 deposits. These results need further studies to confirm the relationship of glomerular C4d deposits with immunopathological variables in cases of IgAN. Key point In a preliminary study on 29 IgA nephropathy (IgAN) patients, we found C4d deposits correlated with interstitial fibrosis/tubular atrophy of Oxford classification of IgAN. There is no significant correlation of C4d deposits with other morphological variables of Oxford classification. C4d deposits showed a negative correlation with C3 deposits. These results need further studies to confirm the relationship of glomerular C4d deposits with immunopathological variables in cases of IgAN. Citation Nasri H, Rafieian-Kopaei M, Ahmadi A, Mubarak M. Association of glomerular C4d deposition with morphologic variables of Oxford classification in IgA nephropathy patients; a preliminary study. Immunopathol Persa. 2016;2(2):e18.

https://semanticscholar.org/paper/b78cec77dba72e2839895597219e77de9c20c09e

Immunopathologia Persa

2

2551512434

1072d4117b59c893fc3972ed03f788ff87fb21c1

Investigating Relations between Traumatic Brain Injury and Relationship Functioning among OIF/OEF Veterans.

Traumatic brain injury (TBI) is one of the most common injuries among Veterans of Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF). TBI can negatively affect Veterans' close relationships, undermining an important source of support to aid recovery and rehabilitation. Given the complex symptom profile of TBI, the present research aimed to pinpoint key mediators of the link between TBI and marital functioning to help identify targets for intervention. Data from married OIF/OEF Veterans (N=188) were drawn from a larger sample. Mediation analyses simultaneously examined the potential roles of depressive, posttraumatic stress disorder (PTSD), and post-concussive symptoms in the association between TBI and Veterans' marital satisfaction. Results revealed associations between TBI and all three types of symptoms; however, only depressive symptoms independently mediated the association between TBI and marital satisfaction. These findings suggest depression as a mechanism by which TBI may interfere with healthy relationship functioning and highlight targets for intervention.

https://semanticscholar.org/paper/1072d4117b59c893fc3972ed03f788ff87fb21c1

Journal of military and government counseling

Journal of military and government counseling

7 4

1-25

32596032

3037969308

45caf20b62a90fe2f9c3b9cc7589c3ae3f53539b

Hubris in World Leaders: Evidence of Neurologic Illness?

Lord David Owen outlines a condition of greater public concern than conventional illness in a leader: exaggerated self-confidence and sense of personal

https://semanticscholar.org/paper/45caf20b62a90fe2f9c3b9cc7589c3ae3f53539b

NEJM Journal Watch

2007

10.1056/JN200702060000006

https://doi.org/10.1056/JN200702060000006

2342958871

90a30d9707f357cfca99b7848922cc950c31d49b

Sauron: embedded single-camera sensing of printed physical user interfaces

3D printers enable designers and makers to rapidly produce physical models of future products. Today these physical prototypes are mostly passive. Our research goal is to enable users to turn models produced on commodity 3D printers into interactive objects with a minimum of required assembly or instrumentation. We present Sauron, an embedded machine vision-based system for sensing human input on physical controls like buttons, sliders, and joysticks. With Sauron, designers attach a single camera with integrated ring light to a printed prototype. This camera observes the interior portions of input components to determine their state. In many prototypes, input components may be occluded or outside the viewing frustum of a single camera. We introduce algorithms that generate internal geometry and calculate mirror placements to redirect input motion into the visible camera area. To investigate the space of designs that can be built with Sauron along with its limitations, we built prototype devices, evaluated the suitability of existing models for vision sensing, and performed an informal study with three CAD users. While our approach imposes some constraints on device design, results suggest that it is expressive and accessible enough to enable constructing a useful variety of devices.

https://semanticscholar.org/paper/90a30d9707f357cfca99b7848922cc950c31d49b

UIST '13

447-456

10.1145/2501988.2501992

https://doi.org/10.1145/2501988.2501992

1984399688

84a0915401b7fb60f7b48c397f192f0ee56ae067

Fertility Profile of A Primitive Tribe, Madhya Pradesh

Abstract In this paper, an attempt has been made to present the socio-economic aspects and demographic characteristic indicating specially fertility of Saharia tribe of Madhya Pradesh. Saharia have been scheduled as one of the seven primitive tribes of the state (74 in India). The major findings of the study reveal that they are the members of traditional society and their literacy rate (23.2 percent) as well as socio-economic status is deplorable low. Taking into consideration about their marital status, it has been noticed that most of the women are to be married at very early age (14.0 ± 0.80 years mean age). A large number of women have been categorized under poor health status and proper clinic facility is unavailable throughout the area. Still birth rate, infant mortality rate and child mortality rate are high. Acceptance of family planning methods is almost nil. So, illiteracy, low socio-economic status, early age at marriage, poor health status of women, unavailability of proper health care facility, still birth, infant and child mortality, nonacceptance of family planning devices, etc. are the attributed reasons which influence their high child-women ratio, crude birth rate, general fertility rate, age specific fertility rate, total fertility rate, gross reproduction rate, mean age of child bearing, general marital fertility rate, age specific marital fertility rate, total fertility rate and gross reproduction rate of women in wed-lock. At the end, few suggestions have been made for implementing under long time multi-stages future development policies which will not only improve their entire socio-economic life but also motivate them in a better fertility behaviour.

https://semanticscholar.org/paper/84a0915401b7fb60f7b48c397f192f0ee56ae067

The Anthropologist

5

161 - 167

10.1080/09720073.2003.11890798

https://doi.org/10.1080/09720073.2003.11890798

2768810243

998fe618089c49b0323c811586bd4eb32ae1e864

Einstein's Simple Mathematical Trick -and the Illusion of a Constant Speed of Light

It is shown how Einstein achieves the illusion of lightspeed invariance by employing a simple mathematical trick—and magically abolishing the aether. As if part of a "conspiracy" against man's efforts to obtain knowledge of the physical world, Nature has a “trick” of its own in providing the illusion of lightspeed invariance. The illusion works remarkably well, thanks to length contraction and clock slowing both of which are induced by absolute motion with respect to aether. Einstein’s illusion and Nature’s illusion, however, conceal the physical reality that the one-way speed of light, contrary to a strict interpretation of Einstein’s 2 nd postulate, is NOT

https://semanticscholar.org/paper/998fe618089c49b0323c811586bd4eb32ae1e864

Applied Physics research

5

85

10.5539/APR.V5N4P85

https://doi.org/10.5539/APR.V5N4P85

2137452803

e48c3e3c804c2c26cfb4797a595d31c1ee874f71

New Approaches in 3D Geomechanical Earth Modeling

In this paper two new approaches for building 3D Geomechanical Earth Model (GEM) were introduced. The first method is a hybrid of geostatistical estimators, Bayesian inference, Markov chain and Monte Carlo, which is called Model Based Geostatistics (MBG). It has utilized to achieve more accurate geomechanical model and condition the model and parameters of variogram. The second approach is the integration of the models resulted of different estimators for more reliable-robust-accurate estimation, and using Ordered Weighted Averaging (OWA) data fusion. More accurate estimations help to achieve better results with less uncertainty in the stage of data fusion. Ordinary Kriging (OK), Universal Kriging (UK), MBG and OWA were utilized for making 3D GEM of Unconfined Compression Stress (UCS) in a reservoir of an oil field in Dezful Embayment. The results were shown that the accuracy of MBG was twice of UK, whereas the model obtained of OK was unacceptable. The results of OWA were even 40% better than MBG.

https://semanticscholar.org/paper/e48c3e3c804c2c26cfb4797a595d31c1ee874f71

3

1-20

10.22107/JPG.2019.88410

https://doi.org/10.22107/JPG.2019.88410

2952638765

a0ce7354015e3b2552ec877ee344a0899b9a6fa6

The Role of Private and Local Government Health Insurance Schemes in Achieving Universal Coverage : Opportunities and Risks

Although they cover a much smaller population, and mostly those in the higher end of the socio-economic scale, private health insurance (HI) plans and self-insuring (SI) private organizations’ spent almost as much for health services as PhilHealth did in 2005, and spent even more than PhilHealth from 2000 to 2004. For those in the lower end of the socioeconomic scale, provincial and municipal health insurance schemes initiated by local government units (LGUs) are also mushrooming. Both voluntary HI and LGU health plans provide short-term opportunities for widening HI coverage and deepening benefits. On the other hand, the increasing multiplicity of these health financing schemes, many of which are operating outside of PhilHealth, could be a setback for achieving solidarity and equitable universal coverage under the national social health insurance (SHI) system. The existing legal and regulatory instruments to manage the proliferation of private HI and LGU schemes are weak, and eventually unifying these schemes under one SHI program would be a nightmare: the instruments are quite complex and entail high regulatory costs. Thus, given the opportunities and risks inherent in the operation of private HI and LGU health plans, policy makers need to ruminate on what should be their role in the overall evolution of social health insurance in the Philippines, in the context of the larger long-term vision for social health insurance.

https://semanticscholar.org/paper/a0ce7354015e3b2552ec877ee344a0899b9a6fa6

ba60866d0a9a4cf025551d56ec70c87cc9708fa2

Bullying in Schools: International Variations

Although bullying has long been in existence among children, it has only begun to be systematically evaluated in the past ten years. Olweus, a pioneer in the field of bullying research, examined the topic among Scandinavian children. Now research is being conducted in many cultures and countries and the results are surprisingly similar. This study sought to examine the literature across cultures with regard to the prevalence of bullying, the characteristics of both the victim and the bully, and the disclosure by children of bullying behavior. Finally, successful prevention efforts will be discussed.

https://semanticscholar.org/paper/ba60866d0a9a4cf025551d56ec70c87cc9708fa2

2467169206

440378cdf31f86590d4238ee2aa4241cdf9a0e8d

Isolation of bacteria from remote high altitude Andean lakes able to grow in the presence of antibiotics.

High altitude Andean lakes are placed in Puna desert over 4400 above sea level. Completely isolated, they are exposed to extreme environmental factors like high levels of salinity, UV radiation and heavy metals and low concentrations of phosphorus. Nevertheless, they are the habitat of enormous populations of three flamingo species that migrate among these Lakes. Previous reports have determined that bacteria isolated from these environments present high levels of resistance to antibiotics. The aim of this work was to determine the diversity of antibiotic resistant bacteria in water from Andean Lakes and their connection with flamingo enteric biota. Bacteria from water and birds faeces from high altitude Lakes: Laguna (L.) Aparejos, L. Negra, L. Vilama and L. Azul (all are located between 4,200 and 4,600 m altitude) were isolated by plating in five different Antibiotics (ampicillin, 100 microg ml(-1); chloramphenicol, 170 microg ml(-1); colistin , 20 microg ml(-1); erythromycin, 50 microg ml(-1) and tetracycline 50 microg ml(-1)). 56 bacteria were isolated and identified by 16 S rDNA sequencing. Antibiotic resistance profiles of isolated bacteria were determined for 22 different antibiotics. All identified bacteria were able to growth in multiple ATBs. Colistin, ceftazidime, ampicillin/sulbactam, cefotaxime, cefepime, cefalotin, ampicillin and erythromycin were the most distributed resistances among the 56 tested bacteria. The current results demonstrated that antibiotic resistance was abundant and diverse in high altitude Lakes. Also the present article indicates some useful patents regarding the isolation of bacteria able to grow in the present of antibiotics.

https://semanticscholar.org/paper/440378cdf31f86590d4238ee2aa4241cdf9a0e8d

Recent patents on anti-infective drug discovery

Recent patents on anti-infective drug discovery

4 1

66-76

10.2174/157489109787236300

https://doi.org/10.2174/157489109787236300

19149698

2140045912

37053ccde32a444cc4160557d8d48b7246bec611

Israel-On the Margins: The Arab Population in the Israeli Economy

On the Margins: The Arab Population in the Israeli Economy, by Aziz Haidar. New York: St. Martin's Press, 1995. xiii + 182 pages. Bibl. to p. 189. Index to p. 192. $42. Reviewed by Ian S. Lustick Aziz Haidar's book may be added to the list of studies analyzing the gradually less efficient control system that has enforced economic dependence of Arabs on Jews in Israel and, more generally, accounted for Arab political quiescence. Haidar cites research by Majid al-Haj, Sabri Jiryis, Raja Khalidi, Henry Rosenfeld, Moshe Semyonov, Sammy Smooha, Elia Zureik and this reviewer, though unaccountably he makes no mention of the particularly relevant and important work of Kretzer1 and Yiftachel.2 Except for some editing, a few new references, some slightly updated tables, and five paragraphs added to the conclusion, this book is identical to the monograph written by Haidar and published in Tel Aviv in 1990 by the International Center for Peace in the Middle East in Tel-Aviv. Haidar's specific purpose is to demonstrate the marginality of the Arabs of Israel in relation to the Israeli economy as a whole. He traces changes in the character of Arab economic activity as it was affected in the decades following the establishment of Israel by systematically discriminatory policies. These include discrimination in land expropriation, investment, licensing, zoning, education, land and water allocations, infrastructural investment, etc. Haidar makes his argument by drawing on two kinds of data. First, the five chapters that follow the introduction report and interpret Israeli Central Bureau of Statistics data showing large and often growing gaps between the resources and living standards of Jewish and Arab Israelis. This presentation includes the reproduction of more than 30 tables and charts from volumes of the Statistical Abstract of Israel and other official sources published between 1961 and 1989. Second, the penultimate chapter reports the results of fieldwork done in 1987 and 1988 in four Arab localities-Taibe, Maghar, Majd al-Kurum and Kfar Yasif-comparing patterns of economic activity in the late 1980s to patterns existing during the Mandate period and in the first decades of life under Israeli rule. The main foci of both parts of the book are the intrepid, but mostly unavailing, efforts by Arab farmers to sustain agriculture as an important element in the economy of the Arab sector, and central government policies which stifle almost all Arab non-agricultural, service-oriented, commercial, or industrial development which would reach beyond the confines of particular Arab localities or the Arab sector as a whole. Haidar's reports on the four villages are the most interesting portion of the book. Here he uses his intimate knowledge of the communities to enliven the dry data of statistical abstracts and explain the greatly distorted nature of some available quantitative measures of Arab vs. Jewish economic activity. The two different sources of data-the published quantitative data and the fieldwork studies of four villages-give added confidence in the study's conclusions, which is gained by correspondence between the findings generated from the two sources. …

https://semanticscholar.org/paper/37053ccde32a444cc4160557d8d48b7246bec611

Middle East Journal

51

447

284686127

bbd0d6572a08974e1f79331c360c26a1b2c1b41b

4,7-Phenanthrolin-4-ium perrhenate

In the title complex, (C12H9N2)[ReO4], the ions are connected together via hydrogen bonds. The crystal structure comprises alternating layers of cations and anions aligned along the b-axis direction.

https://semanticscholar.org/paper/bbd0d6572a08974e1f79331c360c26a1b2c1b41b

Acta Crystallographica Section E-structure Reports Online

62

10.1107/S1600536806016771

https://doi.org/10.1107/S1600536806016771

2061335666

061e7e8753384e263c469239fa7e3649698a940b

Simultaneous Quantification of 6,7-Di-Hydroxyligustilide and Gastrodin in Rat Plasma by LC-MS: Application to Pharmacokinetic Study of Tianshu Capsule

SUMMARY. A LC-MS method was developed and validated for simultaneous determination of 6, 7-di-hydroxyligustilide and gastrodin in rat plasma, and which was subsequently applied in the pharmacokinetic analysis of an administration of a Chinese herbal extract containing Chuanxiong Rhizoma and Gastrodia Elata Rhizome, i.e. TianShu capsule against migraine. The analytes were separated on a Kromasil C18 column with a gradient elution program and detected without interference in the selected ion monitoring mode with positive electrospray ionization. The linear range was 0.010-10.0 μg/mL for 6,7-di-hydroxyligustilide and 0.025-25.0 μg/mL for gastrodin with the limit of quantitation of 0.01 and 0.025 μg/mL, respectively. The intra-day and inter-day precisions for the entire validation were less than14.7 % of RSD. The pharmacokinetic parameters indicated that 6, 7-di-hydroxyligustilide and gastrodin are absorbed rapidly and reached a maximum concentration within one hour, which was consistent with the clinical requirements for the rapid relieving the symptoms of migraine.

https://semanticscholar.org/paper/061e7e8753384e263c469239fa7e3649698a940b

Latin American Journal of Pharmacy

781060781

fab0316676496f3104cdb16cbeacfaecc32ec3a7

Motor evoked potentials (MEPs) and H-reflexes are not equally sensitive to voluntary motor commands

To investigate the sensitivity to changes in excitability of motoneuron pool dependent on voluntary motor commands, we recorded motor evoked potentials (MEPs) and H-reflexes from the right flexor carpi radialis (FCR) muscle of normal human subjects. Amplitudes of MEPs were always larger than those of the H-reflex in both tonic and phasic muscle contractions. Furthermore, amplitudes of MEP and H-reflex were larger in phasic than in tonic muscle contraction. These results indicate that there are differences in the sensitivity to changes in motoneuronal excitability related to the production of excitatory postsynaptic potentials for H-reflex and MEP responses, respectively.

https://semanticscholar.org/paper/fab0316676496f3104cdb16cbeacfaecc32ec3a7

Brain Research

Brain Research

764

273-276

10.1016/S0006-8993(97)00598-2

https://doi.org/10.1016/S0006-8993%2897%2900598-2

9295224

2045520715

916400ae1fcdca5822d3327e24ca1a40f6c109f2

Effect of dry deposition, washout and resuspension on radionuclide ratios after the Chernobyl accident.

The temporal variations of radionuclide ratios in air and deposition samples collected simultaneously at Munich-Neuherberg (F.R.G.) after the Chernobyl accident have been studied. Until 8 May 1986, the radionuclides investigated were 99Mo, 103Ru, 106Ru, 110mAg, 125Sb, 129mTe, 132Te, 131I, 134Cs, 137Cs, 140Ba, 141Ce and 144Ce. After 8 May, 99Mo, 110mAg, 125Sb, and the Ce isotopes were below the detection limits. Considerable temporal variations of the above radionuclides, relative to 137Cs, were observed in air as well as in deposition. In air the temporal variations reflect the arrival of different parts of the reactor plume with different elemental composition. In deposition, the temporal patterns were quite different from those in air for a given radionuclide. This is explained by varying contributions of dry and wet deposition. Until 8 May, the washout ratios of the above radionuclides covered a range from 240 to 5600, with smaller variations for all radionuclides within one event (e.g. 460-910), and larger variations from one event to another (e.g. 460-3300 for 137Cs). The dry deposition velocity of 137Cs was found to be 0.27 cm s-1, similar to that of 110mAg, aerosol 131I and 140Ba (0.37, 0.13 and 0.15 cm s-1). Another group of radionuclides includes 103Ru, 106Ru, 125Sb, total 131I and 132Te with dry deposition velocities of 0.08, 0.10, 0.07, 0.03 and 0.08 cm s-1 and with temporal variations in deposition which are quite different from those of the first group. From 8 May to the end of June, the washout ratios increased to values between 1500 and 24,000, with the exception of iodine, which had considerably lower washout ratios of between 37 and 4400. These later effects are explained by resuspension and, in the case of iodine, by remobilization of gaseous species.

https://semanticscholar.org/paper/916400ae1fcdca5822d3327e24ca1a40f6c109f2

The Science of the total environment

The Science of the total environment

90

1-12

10.1016/0048-9697(90)90181-S

https://doi.org/10.1016/0048-9697%2890%2990181-S

2305238

2086847655

4454834d944d2d4afa651bda169f0acaf0bde835

Intelligence and Giftedness: Changes in the Structure of the Brain**

This essay offers an overview of research that recently changed the concepts of intelligence and giftedness. First, it considers the importance of the brain, its organization and functions. Second, it examines different theories about intelligence and the possibility of boosting it. Third, it considers the changes that occur in the human brain structure as a consequence of the interaction between the genetic traits of individuals and the challenges which they experience as they are raised. My objective is to point out that there is a scientific basis for educators to trigger decisive changes both in the behavior of students and in their biological structure by offering opportunities that are likely to increase their potential.

https://semanticscholar.org/paper/4454834d944d2d4afa651bda169f0acaf0bde835

Gifted Education International

13

226 - 238

10.1177/026142949901300304

https://doi.org/10.1177/026142949901300304

2137103572

909a4eed4004d684c2d403d711dab20bc4c33642

Sleep findings in Brazilian children with congenital Zika syndrome

Study Objectives Zika virus infection during pregnancy may result in congenital Zika syndrome (CZS), whose characteristics are being described. Methods The present study aimed to investigate the sleep characteristics of 136 infants/toddlers (88 with CZS and 48 with typical development (TD), age and gender matched, 60% girls and 40% boys in both groups) using the Brief Infant Sleep Questionnaire. The ages of children in both groups ranged from 5 to 24 months (CZS 15.9 ± 0.4 vs. TD 15.8 ± 1.0 months, P= 0.90). Results The results show that 34.1% of CZS and 2% of TD children were defined as poor sleepers, 15% of CZS and 2% of TD children remained awake at night for a period longer than 1 hour, and 24% of CZS and 2% of TD children slept less than 9 hours. The CZS group showed shorter total sleep time (CZS 11.24 ± 2.6 vs. TD 12.02 ± 1.9 hours, P= 0.03) and shorter nocturnal sleep duration than the TD group (CZS 8.2 ± 0.2 vs. TD 9.4 ± 0.2 hours, P= 0.0002). In contrast to the control group (P= 0.02, r= -0.34), in the CZS group, no correlation was found between age and nocturnal wakefulness. Future studies should explore these data in relation to the development and maturation of the central nervous system of these children. Conclusions Considering the well-known consequences of poor sleep quality on health in several populations, the presence of sleep disorders should be considered in CZS using multidisciplinary treatments.

https://semanticscholar.org/paper/909a4eed4004d684c2d403d711dab20bc4c33642

Sleep

SLEEP

41

&NA;

10.1093/sleep/zsy009

https://doi.org/10.1093/sleep%2Fzsy009

29325155

2781652931

fe3d951a1aef14807ae43d2b8c10396fa5b4ace8

Family practice and internal medicine clinical judgment in a university setting.

There were no significant differences between family practice and internal medicine residents in the proportion of total diagnoses that were reasonable (72 percent and 77 percent, respectively) and unreasonable (14 percent and 15 percent, respectively) or average number of consultations requested per examination (.15 and .16, respectively). There was a significant difference between the two types of physicians in the average number of laboratory tests requested per examination (1.42 per family practice and 1.88 per internal medicine) and average number of x-ray examinations requested per examination (0.35 for family practice and 1.02 for internal medicine). The average length of examination for internal medicine tended to be longer than for family practice. Although generalizability of this study is limited, the results suggest that there may be important differences in the practice patterns of family practice and internal medicine with implications for training programs.

https://semanticscholar.org/paper/fe3d951a1aef14807ae43d2b8c10396fa5b4ace8

The Journal of family practice

The Journal of family practice

22 5

443-8

3701284

2337428326

9f7ff951d316ec7849554d0cf26ff5f1c8b0addd

Glossary of terms related to load management

Part I of the Glossary of Terms related to Load Management has been prepared by the Terminology Task Force of the Load Management Subcommittee. The glossary contains many definitions of terms used by the electric utility industry concerning the subject of Load Management. The terms are listed in alphabetical order and cross-referenced where necessary.

https://semanticscholar.org/paper/9f7ff951d316ec7849554d0cf26ff5f1c8b0addd

IEEE Transactions on Power Apparatus and Systems

104

2381-2386

171975465

29ae0de4dbc8c7d837563421601a79587287efd4

Reducing the time needed to conduct conditioned place preference testing

The objective of the present experiment was to demonstrate whether four days of twice-a-day conditioned place conditioning produces a preference that is equivalent to that produced by using eight days of once-a-day training. Two doses of the amphetamine-like stimulant drug cathinone (0.2 and 1.6 mg/kg) were selected to demonstrate the effectiveness of twice-a-day (morning-vehicle; afternoon-drug pairings) conditioning. The 0.2 mg/kg dose of cathinone failed to affect the expression of place preference, whereas the 1.6 mg/kg dose produced a significant (p less than 0.002) shift in CPP from baseline when compared to previous measurements. These results demonstrate that twice-a-day pairings over four days effectively shorten the total duration of training without changing the development of place preference produced by once-a-day over eight conditioning day schedule.

https://semanticscholar.org/paper/29ae0de4dbc8c7d837563421601a79587287efd4

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Progress in Neuro-Psychopharmacology and Biological Psychiatry

16

969-976

10.1016/0278-5846(92)90114-T

https://doi.org/10.1016/0278-5846%2892%2990114-T

1513934

2080993215

c3ba12f7291f0b76c7e67fa634f761235345f4cd

Sequence analysis of the hepatitis B virus pre-C region in hepatocellular carcinoma [HCC] and nontumoral liver tissues from HCC patients.

We investigated whether replication-competent pre-C/C defective mutants of hepatitis B virus (HBV) are detectable in primary human hepatocellular carcinoma (HCC) tissues from patients of a geographic area endemic for such mutants. DNAs extracted from formalin-fixed paraffin-embedded HCC samples were checked for the presence of specific HBV DNA sequences using the polymerase chain reaction (PCR). Amplified pre-C regions from nine HCC samples were directly sequenced as were samples of nontumoral liver tissues from five of these patients. The data show that hypervariable distal pre-C sequences were present in all nine HCC samples; this high variability was dependent on point mutations, which led to amino acid substitutions in nearly all cases. Interestingly, seven of the nine HBV DNA-positive samples from HCC tissues (but not samples from peritumoral liver tissue) showed mutations leading to amino acid substitution at the level of a distal cysteine residue. No mutation generating a translationally defective pre-C/C region was detectable in the tumor samples. Otherwise, in four of the six nontumoral liver tissues available from the same patients, a pre-C sequence with an in-frame TAG stop codon was detectable, although in three cases as a component of mixed population.

https://semanticscholar.org/paper/c3ba12f7291f0b76c7e67fa634f761235345f4cd

Virology

Virology

188 2

890-5

10.1016/0042-6822(92)90548-4

https://doi.org/10.1016/0042-6822%2892%2990548-4

1316686

2081540672

959af3daaf84f5581159700676703988a10a3890

Crítica a modelos de avaliação de desempenho de sistemas de saúde

Introduction – In health, the logic of new public management considers the health services as non-state activities. Thus, the role of 'control' reaches the centrality of discussion which the control happens with the state's position on the performance over their 'executing agencies', in another hand, the civil society controls the state through monitoring of the performance of state actions. Under this scenario, the "management by health performance" has defended the idea of using 'performance evaluation models' to measure (and compare) the results from work carried out in health systems as well as serve as an instrument of performance monitoring of public administration by civil society. Objective – Therefore, the aim of this research was to develop a critic of performance evaluation models of health systems deconstructing its ideological content as much as external and internal state control tool, taking as empirical basis the experience of Performance Index of Unified Health System (PIUHS). Method – For this, we used three different methodological moments. Firstly, it was used a narrative review described by Rothers to conduct a critical review on the subject; secondly, it was used the systematic review of literature on the topic 'evaluation of health system performance' making it compatible with a qualitative meta-synthesis of type 'metassumarization'; and thirdly, it was used a qualiquantitative methodology, which raised the speeches was made in electronic sites, portals, blogs and web blogs that focused on this Performance Index. It used the Collective Subject Discourse method as a form of analysis beyond the concepts of 'individuation' in Touraine and 'civil society' in Gramsci as an interpretative support of the object under investigation. Results – In the narrative review, the focus was on how the direct contracting results have been expressed in the performance of health systems evaluations. Counter-argument was reinforced attention to the complexity of the field from the point of view of the intense disagreement on key terms as well as the methodological problems in the study of health systems. In metassumarization, the total number of articles (n = 32), 23 articles (71.8%) did not have a definition of "performance". Among the most frequent subsidiary concepts that make up the performance idea is the concept of 'efficiency'

https://semanticscholar.org/paper/959af3daaf84f5581159700676703988a10a3890

2503763919

55b82a1fe0b23a91db350e027c1c67a49834a3e8

Perioperative outcomes of open radical cystectomy in bladder carcinoma : King Chulalongkorn Memorial Hospital experiences

Background Radical cystectomy is the treatment of choice for muscle-invasive and refractory superficial bladder carcinoma. Objectives To report the perioperative outcomes and complications of open radical cystectomy. Materials and Methods We retrospectively reviewed all medical records of patients who underwent open radical cystectomy for bladder carcinoma at our hospital between January 2003 and June 2013. Patients’ demographic data, operative outcomes and pathological study were recorded. Thirty-day postoperative complications were classified by modified Clavien Classification. นพินธต์น้ฉบบั

https://semanticscholar.org/paper/55b82a1fe0b23a91db350e027c1c67a49834a3e8

37d1dd0fbac4973e2ff9a69bc7c9420bee90822e

Design of Bandpass Filter with Wide Stopband

The bandpass filter (BPF) is becoming more and more important in RF front-end because of its easy fabrication and integration [1]. However, microstrip BPF has undesirable harmonic response at frequency doubling and this is harmful to the whole microwave system. Thus, it is urgent to come up with a wide stopband BPF to meet the requirements of microwave system. In the past two decades, a lot of ideas have been presented to design wide stopband filters [2-9]. Due to the bandstop characteristic of photonic band-gap (PBG) [2] and defected ground structure (DGS) [3], they are often used to compress the harmonic response. Wiggly-line [4] can control wave impedance by tuning the coupling line, thus the harmonic is degraded. The overlay dielectric filter [5] makes the velocity of odd and even mode equal. Stepped-impedance resonators (SIRs) [6] are able to ensure the passband performance while push the harmonics to higher frequencies. By loading different elements at the center of resonator [7], harmonic energy can be assimilated effectively. Dissimilar resonators composed of halfand quarter-wavelength SIRs are studied in [8], but the design is complicated and labor intensive, with only 22.5 dB rejection, which is not enough for certain applications. Radiation can also be observed in the stopband, which will influence the performance of the wireless system. Recently, discriminating coupling of open-loop resonators is presented in [9] and the design procedure is simple. However, only the second harmonic can be eliminated. This paper presents a wide stopband BPF by utilizing different resonators and their coupling regions. The second harmonic of BPF can be eliminated with quarter and half wavelength resonators. By choosing different coupling region, the coupling coefficient of the third harmonic equals to zero. The coupling coefficient in the passband is still a desirable value. Meanwhile, the paper gives the analytical theory of this filter. A design example is made and tested. The presented filter is able to suppress the harmonic below 30 dB in a wide band from 6.8GHz to 8.6GHz. Good agreements have been found with simulated results and this validates the presented design.

https://semanticscholar.org/paper/37d1dd0fbac4973e2ff9a69bc7c9420bee90822e

4ff094ded98ae50911b4da65635ae08c619e6b5a

Editor's Letter

After ® ve years as Editor of the International Journal of Systems Science I am standing down, due to commitments with my f̀ull time’ job. During my tenure as Editor the number of submitted papers has doubled, as has the reject rate; paper acceptance is now close to 20%. A new and, I believe, very successful feature of the journal over the past ® ve years has been special issues, edited by international experts in the ® eld, devoted to a theme central to the journal’ s remit. These special issues have covered a wide range of systems engineering areas including economic and software systems, intelligent control and robotics, diagnostics and sensor fusion, as well as topics related to a speci® c domain such as subseas robotics and underwater vehicles. I would like to express my particular thanks to the editors of these special issues for all the hard work in generating such high quality issues. Finally, I would especially like to thank the many journal contributors whose patience and attention to detail has ensured an increasing quality of papers over the past ® ve years. Publisher’s acknowledgement

https://semanticscholar.org/paper/4ff094ded98ae50911b4da65635ae08c619e6b5a

Int. J. Syst. Sci.

International Journal of Systems Science

31

1 - 1

10.1080/002077200291389

https://doi.org/10.1080/002077200291389

20712b39ed471ff56ec120261f62e9df0ebdd3f5

Block-based Comprehension: Exploring and Explaining Student Outcomes from a Read-only Block-based Exam

The success of block-based programming environments like Scratch and Alice has resulted in a growing presence of the block-based modality in classrooms. For example, in the United States, a new, nationally-administered computer science exam is evaluating students' understanding of programming concepts using both block-based and text-based presentations of short programs written in a custom pseudocode. The presence of the block-based modality on a written exam in an unimplemented pseudocode is a far cry from the informal, creative, and live coding contexts where block-based programming initially gained popularity. Further, the design of the block-based pseudocode used on the exam includes few of the features cited in the research as contributing to positive learner experiences. In this paper, we seek to understand the implications of the inclusion of an unimplemented block-based pseudocode on a written exam. To do so, we analyze responses from over 5,000 students to a 20 item assessment that included both block-based and text-based questions written in the same pseudocode as the national exam. Our analysis shows students performing better on questions presented in the block-based form compared to text-based questions. Further analysis shows that this difference is consistent across conceptual categories. This paper contributes to our understanding of the affordances of block-based programming and if and how the modality can help learners succeed in early computer science learning experiences.

https://semanticscholar.org/paper/20712b39ed471ff56ec120261f62e9df0ebdd3f5

SIGCSE

Proceedings of the 50th ACM Technical Symposium on Computer Science Education

10.1145/3287324.3287348

https://doi.org/10.1145/3287324.3287348

2915549126

6916be7d40a4c4831063db4e6bf2275021100c00

Active probing of cloud thickness and optical depth using wide-angle imaging LIDAR.

At most optical wavelengths, laser light in a cloud lidar experiment is not absorbed but merely scattered out of the beam, eventually escaping the cloud via multiple scattering. There is much information available in this light scattered far from the input beam, information ignored by traditional 'on-beam' lidar. Monitoring these off-beam returns in a fully space- and time-resolved manner is the essence of our unique instrument, Wide Angle Imaging Lidar (WAIL). In effect, WAIL produces wide-field (60{sup o} full-angle) 'movies' of the scattering process and records the cloud's radiative Green functions. A direct data product of WAIL is the distribution of photon path lengths resulting from multiple scattering in the cloud. Following insights from diffusion theory, we can use the measured Green functions to infer the physical thickness and optical depth of the cloud layer. WAIL is notable in that it is applicable to optically thick clouds, a regime in which traditional lidar is reduced to ceilometry. Section 2 covers the up-to-date evolution of the nighttime WAIL instrument at LANL. Section 3 reports our progress towards daytime capability for WAIL, an important extension to full diurnal cycle monitoring by means of an ultra-narrow magneto-optic atomic line filter. Section 4 describes more » briefly how the important cloud properties can be inferred from WAIL signals. « less

https://semanticscholar.org/paper/6916be7d40a4c4831063db4e6bf2275021100c00

1567195812

093818aaa4a1007be75d1c80cc18e0a39dc43b04

[A woman with a chronic cough and dyspnoea].

A previously healthy woman in her forties with a six-month history of persistent coughing, breathlessness and fatigue was referred to our hospital for further evaluation. She was initially treated with antibiotics for a possible respiratory tract infection but with only minor effect. A chest x-ray and computer tomography (CT) of the thorax demonstrated a solid tumour in the right lung hilus. Bronchoscopy revealed slight oedema of the bronchial mucous membrane in the area in question. Cytological examination of bronchoalveolar lavage fluid (BAL) showed normal respiratory epithelial cells. Histological examination of a needle biopsy from the tumour showed lymphoproliferative changes of uncertain cause. Magnetic resonance imaging (MRI) of the thorax provided no further information. An electrocardiogram (ECG) revealed signs of left ventricular hypertrophy and sinus bradycardia. Her complaints were palpitations, mild exertional dyspnoea and attenuated heart rate response to exercise. Echocardiography showed increased wall thickness with heterogeneous echogenicity in both ventricles, a slightly enlarged left atrium and mild mitral regurgitation. Tissue Doppler measurements showed impaired relaxation. These findings were suggestive of restrictive cardiomyopathy with diastolic dysfunction. Cardiac MRI confirmed the echocardiographic findings. The tumour was removed by thoracotomy and was shown to be made up of lymphatic tissue with granulomas, consistent with sarcoidosis. The restrictive cardiomyopathy was regarded as a cardiac manifestation of sarcoidosis. The patient was treated with corticosteroids. Clinical follow up with cardiac MRI and echocardiography did not reveal any progression of the cardiac involvement. Cardiac sarcoidosis must be considered in all sarcoid patients because of its significance for prognosis and treatment.

https://semanticscholar.org/paper/093818aaa4a1007be75d1c80cc18e0a39dc43b04

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

132 12-13

1466-9

10.4045/tidsskr.11.0615

https://doi.org/10.4045/tidsskr.11.0615

22766821

191383453

7d9550ae4656fbe491f3bd60f94167f9519fcbf5

Bayesian Deghosting Approach for Multimeasurement Streamer Data

Most common deghosting techniques operating on multimeasurement marine seismic data rely on a ghost model to combine pressure and vertical velocity. The ghost model provides information needed for the optimization of the signal-to-noise ratio in the broadband results. These techniques are, in general, sensitive to the accuracy of such model and can suffer from perturbations, especially at high frequencies: for instance, the coarse sampling in the crossline direction often forces these techniques to rely on a 2D ghost model, and this can induce significant inaccuracies in complex scenarios. Other modelindependent techniques combine the pressure and vertical velocity without the use of a ghost model. Although these suffer less from 3D propagation effects, they often produce suboptimal results for what concerns the S/N. We introduce a novel model-independent deghosting technique called the “Bayesian PZSUM.” This technique utilizes the multimeasurement second-order statistics to estimate the upgoing wavefield optimally in the minimum mean square error (m.m.s.e) sense. We demonstrate the effectiveness of the technique on both synthetic and real data.

https://semanticscholar.org/paper/7d9550ae4656fbe491f3bd60f94167f9519fcbf5

Seg Technical Program Expanded Abstracts

10.1190/SEGAM2014-1075.1

https://doi.org/10.1190/SEGAM2014-1075.1

2317774630

e2a968f847855cda02e4994b341a6e3e0ff3fc65

AUDITOR INDEPENDENCE, DISMISSAL THREATS, AND THE MARKET REACTION TO AUDITOR SWITCHES

The article presents information on the effect of auditor changes on security prices in both a mechanical decision rule and in the possibility that an adverse audit opinion may lead to dismissal. The analysis implies that the stock price response to the announcement of an auditor change depends on the preswitch audit opinion. The author contends that his research proves auditor switches can be good for investors and that even when they are costless, and there is no collusion between auditor and firm, market reaction can be negative.

https://semanticscholar.org/paper/e2a968f847855cda02e4994b341a6e3e0ff3fc65

Journal of Accounting Research

30

1-23

10.2307/2491089

https://doi.org/10.2307/2491089

2332143949

df507e1d2a2f29a5c0d994f930bf98bff9f1b92a

Distributed optical fiber sensor system having a plurality of sensing areas

(wrap up) Respect Monitoring (object) To date civil engineering and building structure, although a single point sensing technology and distributed sensing techniques have been used, it had disadvantages, respectively. (SOLUTION) The present invention, in order to solve these problems, single-point sensing by dividing the distributed sensing region required number with a reflector capable of selectively selecting the pulse train that has passed through the distortion sensing area It combines the advantages of technology and distributed sensing technology, without missing the change in the measured values ​​between the sensor, shorter measurement time, further an object to provide an excellent optical fiber sensor apparatus in spatial resolution. (Select View) FIGURE 1

https://semanticscholar.org/paper/df507e1d2a2f29a5c0d994f930bf98bff9f1b92a

2771055609

d7e936f3815229976e480975c770282f3c25d63d

Development of roadside safety data collection plan

The purpose of this study is to support the roadside aspect of the FHWA High Priority National Research Area on "Highway Safety Design Practices and Criteria." The objectives of this study are to: (1) identify issues and gaps in the state of the knowledge needed to improve the costeffectiveness analysis procedure, to be developed under NCHRP Project 22-9, "Improved Procedures for Cost-Effectiveness Analysis of Roadside Safety Features," and (2) develop data collection plans for those issues and gaps that can be addressed with accident data. A conceptual framework of the cost-effectiveness model was first formulated. A list of research topics that could potentially improve the cost-effectiveness model was identified. Five proposed research studies were developed from the list: (1) Validation of Encroachment Frequency/Rate, (2) Determination of Encroachment Frequency/Rate Adjustment Factors, (3) Effect of Roadside Conditions on Impact Probability and Severity, (4) Distributions of Impact Conditions, and (5) Relationships of Impact Conditions, Performance Limits, and Injury Probability and Severity. Detailed data collection plans were developed for each of the five proposed studies. A 1-day meeting of an expert panel was convened to critically review these data collection plans. Also, a data collection plan for a combined proposed studies 1 and 2 was developed.

https://semanticscholar.org/paper/d7e936f3815229976e480975c770282f3c25d63d

1583815745

d7fa0e2ae536e97cbbbf3aa394d5d360b046a0df

Attitudes toward industry and growth. Working paper 29

Results of a survey of adult residents in Indiana, Armstrong, and Butler counties are reported. Findings indicate that: (1) the adult residents of these counties express strong support for the construction of new manufacturing plants. About 91% of all citizens interviewed were in favor of such plants; (2) much of the support for new industry extends to the construction of large electric power complexes. About 50% of the respondents were in favor of such energy facilities. Such a finding indicates considerably stronger support than would be expected on the basis of overt public response to the concept. Our results clearly suggest that public officials should assess the opinion of the silent majority before reaching a decision on the power complex issue; (3) in general, residents of the study counties are favorably disposed to new people moving into their communities. Support for an influx of new population, however, is not as strong as support for new industry. Apparently, many residents want new industry but are not enthusiastic about the population growth which would be associated with such development; and (4) factors such as sex and education often influence attitudes toward new industry and growth. In regard to power plants, for example,more » men were consistently more supportive than females. In terms of new industry in general, people at the lower educational levels were more likely to favor development.« less

https://semanticscholar.org/paper/d7fa0e2ae536e97cbbbf3aa394d5d360b046a0df

132824137

cf31ef974563d7ff0e036ec58a0ec19dd4160dd2

LILLEHAMMER 1994

This article uses Elias's game model perspective to analyse the planning of the 1994 Winter Olympic Games in Lillehammer. The study shows how the original Olympic plan that was sold to the International Olympic Committee with the slogan of a `Compact Games' won the bid, but was subsequently transformed due to changes in power balances among the domestic and international players who had conflicting interests. For example, the `Green Games' was not part of Lillehammer's original bid and only emerged as a central feature of the event after complex and protracted negotiations among competing interest groups. It is argued that some of the most important aspects connected to mega-events like the Olympics are due not only to `rational' planning processes, but also to how the attendant conflicts and compromises among interest groups lead to unintended outcomes.

https://semanticscholar.org/paper/cf31ef974563d7ff0e036ec58a0ec19dd4160dd2

International Review for the Sociology of Sport

35

282 - 293

10.1177/101269000035003003

https://doi.org/10.1177/101269000035003003

2154648743

bc428a063c344429976b026484ae3061f0e314b7

Cocaine blunts human CD4+ cell activation.

Cocaine is reported to be immunotoxic. The biochemical mechanisms responsible for the immunopharmacological outcomes of cocaine in vivo and in vitro remain, however, to be fully elucidated. Our experimental data confirm that exposure of normal human T cells to micromolar concentrations of cocaine modulates T-cell responses to stimulation by a variety of stimuli, and indicate that cocaine impairs early activation events during CD4+ but not CD4- T-cell stimulation. Pre-incubation of enriched CD4+ T-cell subpopulations that express the homing receptor CD62L with nanomolar concentrations of the endogenous opioid peptide beta-endorphin leads to a more severe impairment of activation than that noted following pre-incubation with micromolar concentrations of cocaine alone. These findings begin to elucidate the molecular and cellular mechanisms of the immunopathology of cocaine. Our data support the proposition that cocaine abuse may place cocaine-abuser HIV-seropositive individuals at increased risk of opportunistic infections.

https://semanticscholar.org/paper/bc428a063c344429976b026484ae3061f0e314b7

Immunopharmacology

Immunopharmacology

28 3

233-40

10.1016/0162-3109(94)90059-0

https://doi.org/10.1016/0162-3109%2894%2990059-0

7852054

2089486944

7d754569a1466341e1b92e481b0d302a0072ec73

Monte Carlo simulation of single-plane magnetically focused narrow proton beams.

We present Monte Carlo simulations of magnetically focused proton beams shaped by a single quadrapole magnet. Such beams are narrowly focused in one longitudinal plane but fan out in the perpendicular plane producing elongated elliptical beam spots (a 'screwdriver' shape). The focused beams were compared to passively collimated beams (the current standard of delivery for small radiosurgery beams). Beam energies considered were relevant to functional radiosurgery and standard radiosurgery clinical applications. Three monoenergetic beams (100, 125, and 150 MeV) and a modulated beam were simulated. Monoenergetic magnetically focused beams demonstrated 28 to 32% lower entrance doses, 31 to 47% larger central peak to entrance depth dose ratios, 26 to 35% smaller integral dose, 25 to 32% smaller estimated therapeutic ratios, 19 to 37% smaller penumbra volumes, and 38 to 65% smaller vertical profile lateral penumbras at Bragg depth, compared to the collimated beams. Focused modulated beams showed 31% larger central peak to entrance dose ratio, and 62 to 65% smaller vertical lateral penumbras over the plateau of the spread out Bragg peak. These advantages can be attributed to the directional acceleration of protons in the transverse plane due to the magnetic field. Such beams can be produced using commercially available assemblies of permanent rare earth magnets that do not require electric power or cryrogenic cooling. Our simulations suggest that these magnets can be inexpensively incorporated into the beam line to deliver reduced dose to normal tissue, and enhanced dose to elongated elliptical targets with major and minor axes on the order of a few centimeters and millimeters, respectively. Such beams may find application in novel proton functional and standard radiosurgery treatments in and around critical structures.

https://semanticscholar.org/paper/7d754569a1466341e1b92e481b0d302a0072ec73

Physics in medicine and biology

Physics in medicine and biology

58 3

535-53

10.1088/0031-9155/58/3/535

https://doi.org/10.1088/0031-9155%2F58%2F3%2F535

23306185

2023406619

5c466741ae7a95924152846bdb25dcab24b78f6b

A Geostatistical Perspective for the Surrogate-Based Integration of Variable Fidelity Models

When constructing surrogate models, time/cost constraints make the designer frequently face the dilemma of whether to use a small sample of data obtained from, for example, high fidelity/computationally expensive computer simulations, or, a large one but with low fidelity values. More generally, variable fidelity samples can be the result of: i) different physical/mathematical representations (e.g., inviscid/Euler versus viscous/Navier-Stokes calculations), ii) alternative resolution models (e.g., fine/coarse grids), or, iii) experiments. Ideally, surrogate models should allow: a) the integration of variable-fidelity samples, and, b) provide estimation and appraisal (error) information consistent with the amount and fidelity level of the available data. While there have been significant progress in this area through deterministic modeling and optimization approaches (e.g., correction surfaces, and space mapping), a stochastic perspective such as those provided by the branch of spatial statistics known as geostatistics offers distinctive advantages when satisfying the above referenced requirements (a & b). This paper discusses the effectiveness and requirements of geostatistical methods such as classic and collocated Cokriging for the integration of variable fidelity models. The discussion is illustrated using wellknown analytical functions and, alternative resolution models, in the surrogate-based modeling of a field scale alkali-surfactant-polymer (ASP) enhanced oil recovery (EOR) process.

https://semanticscholar.org/paper/5c466741ae7a95924152846bdb25dcab24b78f6b

10.2514/6.2008-5893

https://doi.org/10.2514/6.2008-5893

2324587370

896cc119cd3a67bacdf5ed5866093b4ac18754b4

The fate of urine nitrogen: A grassland lysimeter study in Ireland

In grazed pasture systems, the nitrogen (N) contained in a cattle urine patch may be up to 1200 kg N ha -1 . The majority of this N is in excess of plant requirements and is vulnerable to environmental loss. In this study, cattle urine was applied at five rates of nitrogen, 0, 300, 500, 700 and 1000 kg N ha -1 to soil monolith lysimeters in late autumn in Ireland. Measurements of gaseous N emissions, nitrate (NO3 ) leaching and pasture N uptake were made for a calendar year following urine application in two consecutive experiments. Increasing the rate of urine N applied increased the cumulative nitrous oxide (N2O) emissions, NO3 leaching and pasture N uptake in years one and two, and the relationships were curvilinear with N recovery diminishing at the higher N rates.

https://semanticscholar.org/paper/896cc119cd3a67bacdf5ed5866093b4ac18754b4

3009365784

d7e238f8f55dc27ede4f15d0e677216da4efbe40

Summary of Presentation on Audio-based Music Similarity Analysis

According to the literatures that have been reviewed, because of the soaring of music industry and internet audio-based music resources, which brings the world into a song-corpus-based era from the old album-based era, there are several types of promising applications based on audio music similarity such as, query music by similarity, automatic play-list generation, automatic Dick Jockey and automatic summarizing and categorization.

https://semanticscholar.org/paper/d7e238f8f55dc27ede4f15d0e677216da4efbe40

7f073f7a773a4f2657724fff89fdd1b66dabd154

Dual Algorithm for Solving Large-Scale Scheduling Systems Control Problem with Hierarchical Structure

Abstract This paper is intended to solve a scheduling control problem of a manufacturing process which is interdisciplinary area of process control and business management. Scheduling is the activity that determines the overall production for the next several periods. The whole process is assumed to consist of several subprojects, and each subproject is serially connected in time. The objective function to be minimized is an aggregate quadratic loss which is derived from the resource-periods required and from the movement of resources. The mathematical model of the overall scheduling problem is obtained as a 2-level hierarchical quadratic programming problem. The dual problem is formulated applying Fenchel's duality principle to this scheduling problem. The iterative algorithm to solve the dual problem is easily obtained by taking into account the hierarchical structure of the primal problem. The algorithm obtained is called the dual algorithm in this paper. This results lead to realize the actual scheduling systems control problem with much less computational efforts and also with much less computer memory in comparison to solving the original primal problem numerically. Some numerical examples are included.

https://semanticscholar.org/paper/7f073f7a773a4f2657724fff89fdd1b66dabd154

IFAC Proceedings Volumes

5

170-175

10.1016/S1474-6670(17)68402-7

https://doi.org/10.1016/S1474-6670%2817%2968402-7

2726680479

7d64650e6366d5bfee1f14de3e5d0e5d0da7843f

Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin.

Glucocorticoids (GCs) are highly detrimental to skin integrity and function both when applied topically for anti-inflammatory treatments and during conditions of circulating excess, e.g., Cushing's syndrome. Within target tissues, GC availability is regulated at a prereceptor level, independently of systemic levels, by isozymes of 11β-hydroxysteroid dehydrogenase (11β-HSD) that interconvert active cortisol and inactive cortisone. Many of the adverse effects of GCs on skin are also reminiscent of the natural aging process. 11β-HSD1 (which activates cortisol), but not 11β-HSD2 (which inactivates cortisol), was expressed in epidermal keratinocytes and dermal fibroblasts in human skin and also in outer hair follicle root sheath cells in murine skin. 11β-HSD1 activity was present ex vivo in both species and increased with age in human skin tissue explants. In primary human dermal fibroblasts (HDF) from both photoprotected and photoexposed sites, 11β-HSD1 also increased with donor age. Additionally, photoexposed HDF displayed higher 11β-HSD1 mRNA expression than donor-matched photoprotected HDF. GC treatment of HDF caused upregulation of 11β-HSD1 mRNA levels independent of donor age or site. The age- and site-associated increase in dermal 11β-HSD1, and the ensuing increased local GC activation, may contribute to the adverse changes in skin morphology and function associated with chronological aging and photoaging.

https://semanticscholar.org/paper/7d64650e6366d5bfee1f14de3e5d0e5d0da7843f

The Journal of investigative dermatology

The Journal of investigative dermatology

131 1

30-6

10.1038/jid.2010.257

https://doi.org/10.1038/jid.2010.257

20739946

2003953254

28067eb205af24e14c6b0529dc2807ddfe0d48fa

Transfer plate wetting system and oriented solution transferring system

A transfer plate wetting system and an oriented solution transferring system. The transfer plate wetting system comprises a first plate wetting device. The first plate wetting device comprises an oriented agent storage box (7), an oriented agent solvent storage box (8), a nozzle (10), and a pipeline connecting piece (T) for communicating the oriented agent storage box (7), the oriented agent solvent storage box (8) and the nozzle (10), the nozzle (10) being constructed to be capable of spraying an oriented solution containing an oriented agent and an oriented agent solvent. The transfer plate wetting system can be used for manufacturing a thickness-uniform oriented layer, thereby improving the display effect of a display device.

https://semanticscholar.org/paper/28067eb205af24e14c6b0529dc2807ddfe0d48fa

2924793728

4844d1d221f5b16525ecbc9b16111fbc5c1c429d

Line‐blanketed Spherically Extended Model Atmospheres of Hot Luminous Stars with and without Winds

We have found that our spherical, hydrostatic, nonlocal thermodynamic equilibrium (non-LTE) metal line-blanketed model atmospheres are able to reproduce the spectral energy distributions of the bright B giants b and e Canis Majoris, including the extreme ultraviolet, where previous models have failed (J. P. Aufdenberg, P. H. Hauschildt, & E. Baron 1999, MNRAS, 302, 599; J. P. Aufdenberg, P. H. Hauschildt, S. N. Shore, & E. Baron 1998, ApJ, 498, 837). The brightest stellar source of EUV radiation longward of 400 A, e CMa is an extremely important star because it produces more hydrogen-ionizing flux than all nearby stars combined. Because of their proximity to the Sun, these two stars provide the rare opportunity to directly test predictions of theoretical stellar continua below the Lyman limit. These stars have precisely measured angular diameters, trigonometric parallaxes, and bolometric fluxes, and we have shown that the best-fitting models fall on the Hertzsprung-Russell diagram within the small error boxes provided by these observations. Within these constraints, we were able to compare our synthetic spectra to the observed spectral energy distributions of these B stars in absolute units, a rarity in stellar atmosphere analyses. Observations show a large EUV flux excess compared with plane-parallel model atmospheres (J. P. Cassinelli et al. 1995, ApJ, 438, 932; J. P. Cassinelli et al. 1996, ApJ, 460, 949). This led to the suggestion that various scenarios such as X-ray heating and the presence of a stellar wind were responsible for the mismatch between theory and observation. We discovered that a combination of metal line blanketing and spherical geometry present in our model atmospheres produced significantly more EUV flux than (otherwise similar) plane-parallel atmospheres without the need for these ad hoc mechanisms. These findings are in agreement with studies of B star H ii regions which also show evidence for excess EUV flux from B stars relative to plane-parallel model predictions (R. J. Reynolds 1985, AJ, 90, 92; R. J. Reynolds & S. L. Tufte 1997, ApJ, 439, L17). Our models for b and e CMa represent the only spherical, non-LTE line-blanketed models of B stars in the literature. Surprisingly, we have found that the combination of spherical geometry, line blanketing, and surface gravities as high as will produce significantly different model temlog g p 3.5 perature structures and synthetic EUV spectra relative to otherwise similar plane-parallel models over a range in effective temperature of 18,000–28,000 K. It is the combination of the spherical geometry and the line blanketing, not the non-LTE aspects, that is the most important factor creating this effect. We believe an important factor which shifts the surface cooling/ backwarming to greater depths in the spherical models is the reduced optical depth seen by photons in a spherical geometry relative to that in a semi-infinite plane-parallel geometry, for a given physical depth. As a result, in the spherical models, backwarming begins at a greater depth than in the plane-parallel models. These deeper layers are intrinsically warmer, so that the temperature of the EUV continuum-forming layers are at a higher temperature than the EUV continuum-forming layers in the plane-parallel models. We encourage other researchers to reproduce our findings with an independent spherical lineblanketed model atmosphere code. Our models for hot, luminous stars and their winds are thus far the only ones that include metal line blanketing and combine the inner hydrostatic layers with the outer dynamic layers of the atmosphere in a single structure. This is a significant step, particularly regarding the inclusion of full non-LTE metal line blanketing in both the computation of the model atmosphere plus wind and the synthetic spectrum. Model approaches to date have been limited by the use of a spherical gray temperature structure (not fully converged), the lack of full line blanketing, and the Sobolev approximation, which cannot treat overlapping lines or multiple scattering. In our models, the temperature structure is computed from the condition of energy conservation in the comoving frame, full line blanketing is included, and the Sobolev approximation is not used. Moving beyond these models, we have begun to develop a theoretical framework that will self-consistently obtain the velocity structure and the mass-loss rate from radiation-driven wind theory given the effective temperature, radius, and gravity of the star. We have developed a module for the PHOENIX

https://semanticscholar.org/paper/4844d1d221f5b16525ecbc9b16111fbc5c1c429d

Publications of the Astronomical Society of the Pacific

113

119-120

10.1086/317970

https://doi.org/10.1086/317970

2079813451

9c229987ec525c0c43049bcb08ea6a3e8d5d175e

Immature teratoma of gallbladder associated with gliomatosis peritonei, a case report.

The patient was a 9-month-old girl who presented with an abdominal mass. Computed tomography scan revealed that the huge heterogeneous mass with cystic, calcified, and solid components occupied the upper abdomen, and diagnosis of teratoma was made preoperatively. At the operation, a tumor arising from gallbladder and gliomatosis peritonei with intact ovaries were found. This is a rare case report of teratoma that originated in the gallbladder associated with gliomatosis peritonei.

https://semanticscholar.org/paper/9c229987ec525c0c43049bcb08ea6a3e8d5d175e

Journal of pediatric surgery

Journal of pediatric surgery

42 10

E25-7

10.1016/J.JPEDSURG.2007.08.001

https://doi.org/10.1016/J.JPEDSURG.2007.08.001

17923185

1997741812

25623c9515a4861cdadb5bfb0aeebb9baca1cb05

Steady State Sputtering Yields and Surface Compositions of Depleted Uranium and Uranium Carbide bombarded by 30 keV Gallium or 16 keV Cesium Ions.

Depleted uranium that included carbide inclusions was sputtered with 30-keV gallium ions or 16-kev cesium ions to depths much greater than the ions’ range, i.e. using steady-state sputtering. The recession of both the uranium’s and uranium carbide’s surfaces and the ion corresponding fluences were used to determine the steady-state target sputtering yields of both uranium and uranium carbide, i.e. 6.3 atoms of uranium and 2.4 units of uranium carbide eroded per gallium ion, and 9.9 uranium atoms and 3.65 units of uranium carbide eroded by cesium ions. The steady state surface composition resulting from the simultaneous gallium or cesium implantation and sputter-erosion of uranium and uranium carbide were calculated to be U₈₆Ga₁₄, (UC)₇₀Ga₃₀ and U₈₁Cs₉, (UC)₇₉Cs₂₁, respectively.

https://semanticscholar.org/paper/25623c9515a4861cdadb5bfb0aeebb9baca1cb05

10.2172/1184161

https://doi.org/10.2172/1184161

2339681867

5309a9e13eb9c7731653da60ee30cfc5b10b9edd

Use of carboxyhaemoglobin levels to predict the development of diseases associated with cigarette smoking.

Carboxyhaemoglobin (COHb) levels in tobacco smokers vary throughout the day since they are affected by the pattern of tobacco consumption and the rate at which COHb is eliminated. A method is described whereby a single COHb measurement together with a recent smoking history may be used to estimate the average COHb "boost" produced by each cigarette, the total daily carbon monoxide (CO) uptake from smoking, and the mean COHb level throughout the day. These three indices of tobacco smoke absorption were estimated in nine healthy cigarette smokers on different days, each set of three estimations being derived from separate COHb determinations. The indices were reasonably reproducible within the same person, and the differences between people were statistically highly significant (P less than 0-001). For example, the estimates of mean daily COHb level resulting from smoking ranged from 0-7% to 9-3% in smokers who smoked 15 to 40 cigarettes a day. These differences are sufficiently large to distinguish possible differences in the risk of developing diseases such as ischaemic heart disease which may result from the inhalation and absorption of tobacco smoke. The suggested indices also depend less on the time of the blood test and on the daily pattern of smoking than a COHb level alone. The ratio of the COHb boost to the CO yield of a cigarrette may reflect depth of inhalation more accurately than a smoker's self-assessment. Moreover there was little correlation between these two measures of inhalation in the nine subjects studied.

https://semanticscholar.org/paper/5309a9e13eb9c7731653da60ee30cfc5b10b9edd

Thorax

Thorax

30

133 - 140

10.1136/thx.30.2.133

https://doi.org/10.1136/thx.30.2.133

1179308

2051139629

51f58f7dd191dcede986ecd18b3ef1a02e303faa

Stator Frequency Regulation in a Field-Oriented Controlled DFIG Connected to a DC Link

Dispersed generation systems need several elements that should work together. One possible way to connect these elements is through a common dc link. This paper discusses a new control method for the doubly fed induction generator when connected to a dc link. Considerable benefits are obtained in this configuration, because a simple diode bridge can be used on the stator and only an ac/dc power electronic inverter is needed to control the rotor currents. As the ac mains do not impose the stator frequency, this should be regulated to get an appropriate operation of the induction machine. This paper proposes a method to regulate the stator frequency and control the torque based on adjustments of the d - q rotor reference currents by using the field-oriented control. The analysis and synthesis of the control system based on a simplified model is discussed. Simulations and experimental results show that the proposed control exhibits good dynamics in the torque control and in frequency regulation.

https://semanticscholar.org/paper/51f58f7dd191dcede986ecd18b3ef1a02e303faa

IEEE Transactions on Industrial Electronics

IEEE Transactions on Industrial Electronics

61

5930-5939

10.1109/TIE.2014.2311403

https://doi.org/10.1109/TIE.2014.2311403

2024503351

7b05a578ab318b00119b86b5641e66a1cb23a0a9

A Hexameric Transmembrane Pore Revealed by Two-dimensional Crystallization of the Large Mechanosensitive Ion Channel (MscL) ofEscherichia coli*

We have established a reconstitution method of the detergent-solubilized recombinant large mechanosensitive ion channel of Escherichia coli (MscL) that yielded two-dimensional crystals. For that purpose, we have developed a new protocol using Triton X-100 to solubilize and purify the MscL protein. This protocol not only allowed an increase in the protein yield but also made it possible to obtain a homogeneous delipidated and reproducible preparation of the purified protein. When examined by the patch-clamp method MscL channels were found to be fully functional, exhibiting characteristic conductance and activation by pressure. For electron crystallography the homogeneous Triton X-100-purified recombinant MscL was further reconstituted at low lipid-to-protein ratios using Bio-Beads SM2 to remove the detergent. Two-dimensional crystals, exhibiting a p6 plane group symmetry, have been produced and examined by negative stain electron microscopy. Image processing of selected micrographs yielded a projection map at 15-Å resolution that provided the first explicit structural information about the molecular boundary and homohexameric organization of the MscL channels in the membrane bilayer.

https://semanticscholar.org/paper/7b05a578ab318b00119b86b5641e66a1cb23a0a9

The Journal of Biological Chemistry

The Journal of Biological Chemistry

273

14667 - 14670

10.1074/jbc.273.24.14667

https://doi.org/10.1074/jbc.273.24.14667

9614061

1995638805

acc7cc2f85f680968fef8c278a4bad443fff9a5e

RADIATION GRAFTING OF STYRENE ONTO PTFE FILM

Radiation grafting of styrene monomer onto poly(tetrafluoroethylene) (PTFE) film has been investigated. This research is emphasized on the conditioning of PTFE film. It was irradiated by -ray radiation at various irradiation dose from 2.5 – 12.5 kGy with dose rate 1.9 kGy/hour. Irradiated copolymer was then grafted by styrene monomer under various conditions. The results showed that degree of grafting increased by increasing irradiation dose, solvent concentration, temperature and time of grafting. The optimum condition of radiation grafting relatively was obtained at irradiation dose of 10 kGy, 2-propanol solvent, styrene concentration of 40 volume%, temperature and time of grafting of 70 o C and 6 hours each.

https://semanticscholar.org/paper/acc7cc2f85f680968fef8c278a4bad443fff9a5e

Indonesian Journal of Chemistry

6

20-26

10.22146/IJC.21767

https://doi.org/10.22146/IJC.21767

1583889516

df21276b6078add6d449decf57a2a09233664ea5

ANALYSIS OF OIL SHALE RETORT PRODUCTION STREAM GASES FOR SULFUR SPECIES

ABSTRACT Analysis of the sulfur species in the production gas stream of oil shale retorts is important for environmental and process development needs. Combined gas chromatography/mass spectrometry and gas chromatography with flame photometric detection have been applied to the qualitative and quantitative analysis of sulfur species in the production gas stream from six oil shale retorting experiments. Hydrogen sulfide was determined to be the most abundant species and represented approximately 95 percent (wt.) of the sulfur present. Minor sulfur species identified and quantitated include carbonyl sulfide, carbon disulfide, methylmercaptan, ethylmercaptan, propylmercaptan, and thiophene. Sulfur dioxide was not identified during any of the retorting experiments studied. The distribution of these sulfur species from the six retorting experiments is important because it provides a baseline for the design of process control technologies. The importance of the liquid product collection train for control of sul...

https://semanticscholar.org/paper/df21276b6078add6d449decf57a2a09233664ea5

1

235-257

10.1080/07377268308915324

https://doi.org/10.1080/07377268308915324

2315427902