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1,400 | A 58 year old woman has been diagnosed with locally advanced breast cancer and has been recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which antineoplastic drug should be best avoided? | Anthracycline | Alkylating agent | Platinum compound | Bisphosphonates | 0 |
1,401 | Hand foot syndrome is seen with which anticancer drug? | Cisplatin | 5-fluorouracil | Methotrexate | Imatinib | 1 |
1,402 | Thyroid cancer associated with radiation exposure? | Medullary | Papillary | Follicular | Anaplastic carcinoma | 1 |
1,403 | Gene affected in breast cancer? | WT1 | p53 | RAS | p83 | 1 |
1,404 | A 50 year old woman, Hema has been diagnosed with locally advanced breast cancer and recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which antineoplastic drug should be best avoided | Anthracycline | Alkylating agent | Platinum compound | Bisphosphonates | 0 |
1,405 | In Duke's classification of cancer rectum, B2 denotes - | Growth extends to perirectal fat | Regional nodes involved | Limited to thickness of bowel wall | Hepatic metastasis | 2 |
1,406 | Endometrial cancer involving 50% of endometrium, extending to vagina, lymph nodes negative with positive peritoneal cytology is staged as | 3a | 3b | 3c1 | 3c2 | 1 |
1,407 | A study is looking at breast cancer of women compared cases with non-cases, and found that 75/100 cases used calcium supplements compared with 25/100 of the non-cases. Calculate Cross product ratio | 9 | 6 | 3 | 12 | 0 |
1,408 | Carbohydrate tumor marker for breast cancer: | CA 15-3 | CA 125 | CA 34 | CA 19-9 | 0 |
1,409 | Which of the following benign condition can mimic cancer in the breast? | Accessory Axillary Breast Tissue | Fat necrosis | Fibrocystic disease | Granulomatous Mastitis | 1 |
1,410 | Which of the following therapy is known to stimulate progenitor megakaryocytes and used in Rx of Cancer Chemotherapy-Induced Thrombocytopenia? | IL-2 | IL-6 | IL-8 | IL-11 | 3 |
1,411 | Roopa Devi, a 65-year-old female with ovarian cancer is being treated with cisplatin-bassed chemotherapy. All of the following are used to limit the toxicity of cisplatin except: | N-acetylcysteine | Slow rate of infusion | Chloride diuresis | Amifostine | 0 |
1,412 | Select the drug which is used exclusively in organ transplantation and autoimmune diseases, but not in cancers: | Cyclophosphamide | Cyclosporine | Methotrexate | 6-Mercaptopurine | 1 |
1,413 | False about medullary cancer thyroid | Secrete Calcitonin | 20-25% are familial | Diarrhea are seen in 30% | These cancers take up Radioactive Iodine | 3 |
1,414 | Type IIIB Endometrial cancer (FIGO) is | Endometrial cancer invading cervical stroma | Endometrial cancer with vaginal involvment | Endometrial cancer involving uterine adnexa | Endometrial cancer invading Pelvic lymph nodes | 1 |
1,415 | Most common type cancer gallbladder in a patient with gallstones | Adenocarcinoma | squamous carcinoma | Adenosquamous carcinoma | Liposarcoma | 0 |
1,416 | Chemotherapeutic drug effective in the treatment of epithelial ovarian cancer is:a) Carboplatinb) Paclitaxelc) Cyclophosphamided) Methotrexate karnatka | ac | a | ab | bc | 2 |
1,417 | Most common subtype of thyroid cancer is? | Medullary carcinoma | Papillary carcinoma | Follicular carcinoma | Anaplastic carcinoma | 1 |
1,418 | A 55-year-old female presents to the surgeon with breast symptoms. Her right breast is swollen, red and tender. The physician palpates a firm area in the breast and suspects inflammatory breast cancer. Which of the following best describes the histological changes observed in this disorder? | Acute inflammation in breast carcinoma | Chronic inflammation in breast carcinoma | Dermal lymphatic invasion by cancer cells | Epidermal invasion by cancer cells | 2 |
1,419 | A 27-yrs-old librarian has been worried that the small lymph nodes she can palpate in her groin are a sign of lymphoma. She also worries about developing laryngeal cancer due to the second-hand smoke she is exposed to at home. For a diagnosis of hypochondriasis, her symptoms should have been present for at least what period of time? | 1 month | 3 month | 6 months | 1 year | 2 |
1,420 | Which among the following is true statement regarding breast cancer metastasis? | Metastases occur after breast cancers acquire their own NEW blood supply. | Batson plexus facilitates metastasis to the lung. | Natural killer cells have no role in breast cancer immunosurveillance. | 20 % of women who develop breast carcinoma metastases will do so within 60 months of treatment. | 0 |
1,421 | Triple negative breast cancer- What is true - | It has good prognosis | There are no receptors postitve for ER, PR and HER2 NEU | It is a cancer that cannot be diagnosed by triple assessment | Three Radiologic investigations ic CT scan, MRI and USG are needed for diagnosis | 1 |
1,422 | The lymph nodes first involved in cancer of the skin of the scrotum are - | Superfical inguinal | External iliac | Para aortic | Gland of Cloquet | 0 |
1,423 | Thyroxine is used in the treatment of which thyroid cancer: | Medullary | Radiation induced | Anaplastic | Papillary | 3 |
1,424 | A patient with cancer developed an extreme degree of radiation toxicity. Further history revealed that the dose adjustment of a particular drug was missed during the course of radiotherapy. Which of the following drugs required a dose adjustment during radiotherapy in order to prevent radiation toxicity | Vincristine | Dactinomycin | Cyclophosphamide | 6–Mercaptopurine | 1 |
1,425 | A 37 year old woman has cyclical premenstrual pain. Her breasts have a "lumpy-bumpy" texture on palpation. A biopsy is performed. The histopathologic features include small cysts lined by epithelial cells with apocrine metaplasia, calcium deposits, areas of fibrosis, increased number of acini (adenosis), and foci of florid hyperplasia of ductal epithelium. Which of these changes increase the risk of breast cancer? | Adenosis | Apocrine metaplasia | Calcium deposits | Epithelial hyperplasia | 3 |
1,426 | A 70 year old male chronic smoker is diagnosed of having cancer of the urinary bladder. It is confined to the trigone and extention is upto the submucosa. The management would be | Complete transurethral resction | Complete transurethral resection with intravesical chemotherapy | Palliative radiotherapy | Radical cystectomy | 1 |
1,427 | In patients with breast cancer, chest wall involvement means involvement of any one of the following structure except | Serratus anterior | Pectoralis'Majar | Intercostal Muscles | Ribs | 1 |
1,428 | A female undergone surgery for left breast cancer 3 yrs back now developed blue nodule on same side - | Lymphangiosarcoma | Recurrence | Hemangioma | Cellulitis | 0 |
1,429 | Cranial irradiation is also indicated in the treatment of which variety of lung cancer? | Squamous cell carcinoma | Non small cell cancer | Small cell cancer | Adenocarcinoma | 2 |
1,430 | Subcapsular orchiectomy is done for cancer of ? | Testes | Prostate | Penis | Urethra | 1 |
1,431 | A patient undergoes a total gastrectomy because of a proximally located gastric cancer. After the surgery, which of the following digestive enzymes will be produced in inadequate amounts? | Amylase | Chymotrypsin | Lipase | Pepsin | 3 |
1,432 | Which of the following vitamin deficiency is found in patients with gastric cancer ? | Vitamin C | Vitamin B 12 | Vitamin A | Vitamin D | 1 |
1,433 | Hypercalcemia related to malignancy is seen in which of the following cancers? | Multiple myeloma | Lung carcinoma | Carcinoma breast | All the above | 3 |