hcaoaf/MoleculeQA · Datasets at Hugging Face

text stringlengths 3 799
Option A: It is used in the treatment of schizophrenia in adult patients.
Option B: It is used widely in other countries in the treatment of acute pain.
Option C: It is used in the treatment of acute pain and chronic arthritis.
Option D: It can be used in the treatment of acute pain and chronic arthritis.
" C
2327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as therapy, both oral and intravenous, in human health and disease.
Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.
Option C: It is used as a therapy for treating Parkinson's disease.
Option D: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
" C
179344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)O[C@H]1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Option B: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents.
Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
Option D: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.
" D
2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.
Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.
Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" A
5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in therapy of chronic arthritis.
Option B: It is used for intravenous therapy.
Option C: It may be treated with medical therapy.
Option D: It is used for the therapy of chronic arthritis.
" B
148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It plays a central role in the therapy of many solid tumors including breast and lung cancer.
Option B: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia.
Option C: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.
Option D: It plays a central role in the therapy of ovarian, breast, and lung cancer.
" A
38409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CSC(=C1)C(=O)C2=C(C(=C(C=C2)OCC(=O)O)Cl)Cl
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is commonly used as a first line therapy in the treatment of hypertension.
Option B: It is marketed for the treatment of hypertension.
Option C: It is used for the treatment of hypertension.
Option D: It is used in the treatment of schizophrenia in adult patients.
" B
2162 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used as an antihypertensive drug.
Option B: It is used as a lipid-lowering drug.
Option C: It is being studied as an investigational drug as part of a strategy to cure HIV infection.
Option D: It is used for the treatment of opioid addiction.
" A
4601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option C: It restores the motor disturbances induced by neuroleptics, in particular the hyperkinesia.
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" C
3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCC(CCC)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis.
Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.
Option C: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic.
Option D: It is used as second-line therapy in patients who have inadequate response or intolerance to allopurinol, and should be avoided in patients with cardiovascular diseases.
" C
4917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.
Option B: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" A
977 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: O=O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in therapy of chronic arthritis.
Option B: It is used for the therapy of chronic arthritis.
Option C: It is used predominantly to treat chronic arthritis.
Option D: It may be treated with medical therapy.
" D
4735 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is expected to make Clostridium difficile associated diarrhea therapy more accessible.
Option B: Therapy requires careful monitoring.
Option C: It has helped dissolve kidney stones in experimental animals.
Option D: It may be treated with medical therapy.

Option A: It is used in the treatment of schizophrenia in adult patients.

Option B: It is used widely in other countries in the treatment of acute pain.

Option C: It is used in the treatment of acute pain and chronic arthritis.

Option D: It can be used in the treatment of acute pain and chronic arthritis.

" C

2327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as therapy, both oral and intravenous, in human health and disease.

Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.

Option C: It is used as a therapy for treating Parkinson's disease.

Option D: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

" C

179344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(=O)O[C@H]1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

Option B: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents.

Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.

Option D: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.

" D

2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.

Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.

Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" A

5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used in therapy of chronic arthritis.

Option B: It is used for intravenous therapy.

Option C: It may be treated with medical therapy.

Option D: It is used for the therapy of chronic arthritis.

" B

148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It plays a central role in the therapy of many solid tumors including breast and lung cancer.

Option B: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia.

Option C: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.

Option D: It plays a central role in the therapy of ovarian, breast, and lung cancer.

" A

38409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CSC(=C1)C(=O)C2=C(C(=C(C=C2)OCC(=O)O)Cl)Cl

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is commonly used as a first line therapy in the treatment of hypertension.

Option B: It is marketed for the treatment of hypertension.

Option C: It is used for the treatment of hypertension.

Option D: It is used in the treatment of schizophrenia in adult patients.

" B

2162 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used as an antihypertensive drug.

Option B: It is used as a lipid-lowering drug.

Option C: It is being studied as an investigational drug as part of a strategy to cure HIV infection.

Option D: It is used for the treatment of opioid addiction.

" A

4601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).

Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option C: It restores the motor disturbances induced by neuroleptics, in particular the hyperkinesia.

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" C

3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CCCC(CCC)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis.

Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.

Option C: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic.

Option D: It is used as second-line therapy in patients who have inadequate response or intolerance to allopurinol, and should be avoided in patients with cardiovascular diseases.

" C

4917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.

Option B: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" A

977 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: O=O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used in therapy of chronic arthritis.

Option B: It is used for the therapy of chronic arthritis.

Option C: It is used predominantly to treat chronic arthritis.

Option D: It may be treated with medical therapy.

" D

4735 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is expected to make Clostridium difficile associated diarrhea therapy more accessible.

Option B: Therapy requires careful monitoring.

Option C: It has helped dissolve kidney stones in experimental animals.

Option D: It may be treated with medical therapy.