hcaoaf/MoleculeQA · Datasets at Hugging Face

text stringlengths 3 799
" B
6274 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=C(NC=N1)C[C@@H](C(=O)O)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It provides a new and promising therapy for the treatment of PPD in adult females.
Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.
Option C: It is a useful therapy in all patients with low histamine levels.
Option D: It is commonly used as a first line therapy in the treatment of hypertension.
" C
2833 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option B: It interrupts the cycle of monosodium urate crystal deposition in joint tissues and the resultant inflammatory response in patients with gout.
Option C: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
Option D: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role.
" B
5281613 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
Option B: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.
Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.
Option D: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.
" C
446157 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.
Option B: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.
Option D: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.
" A
5950 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H](C(=O)O)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used predominantly to treat chronic arthritis.
Option B: It is expected to make Clostridium difficile associated diarrhea therapy more accessible.
Option C: It may be treated with medical therapy.
Option D: It has helped dissolve kidney stones in experimental animals.
" D
938 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CN=C1)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.
Option B: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic.
Option C: It is effective in lowering low density lipoprotein (LDL) cholesterol and raising high density lipoprotein (HDL) cholesterol, which makes this agent of unique value in the therapy of dyslipidemia.
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" C
2809 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in the treatment of schizophrenia in adult patients.
Option B: It is effective in the treatment of anxiety.
Option C: It is used for the treatment of hypertension.
Option D: It is used for the treatment of schizophrenia symptoms.
" B
3394 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.
Option B: It is widely used for therapy of mild-to-moderate pain and arthritis.
Option C: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms.
Option D: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.
" D
5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.
Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
" D
3658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option B: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role.
Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
" D
5460875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C(C(C(=O)[O-])N)C(=O)N
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.
Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option D: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia.
" D
3039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COP(=O)(OC)OC=C(Cl)Cl
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as therapy, both oral and intravenous, in human health and disease.
Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis.
Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
Option D: It is used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations.
" D
3825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use

" B

6274 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=C(NC=N1)C[C@@H](C(=O)O)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It provides a new and promising therapy for the treatment of PPD in adult females.

Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.

Option C: It is a useful therapy in all patients with low histamine levels.

Option D: It is commonly used as a first line therapy in the treatment of hypertension.

" C

2833 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

Option B: It interrupts the cycle of monosodium urate crystal deposition in joint tissues and the resultant inflammatory response in patients with gout.

Option C: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

Option D: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role.

" B

5281613 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).

Option B: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.

Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.

Option D: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.

" C

446157 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.

Option B: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).

Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.

Option D: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.

" A

5950 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C[C@@H](C(=O)O)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used predominantly to treat chronic arthritis.

Option B: It is expected to make Clostridium difficile associated diarrhea therapy more accessible.

Option C: It may be treated with medical therapy.

Option D: It has helped dissolve kidney stones in experimental animals.

" D

938 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CC(=CN=C1)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.

Option B: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic.

Option C: It is effective in lowering low density lipoprotein (LDL) cholesterol and raising high density lipoprotein (HDL) cholesterol, which makes this agent of unique value in the therapy of dyslipidemia.

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" C

2809 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used in the treatment of schizophrenia in adult patients.

Option B: It is effective in the treatment of anxiety.

Option C: It is used for the treatment of hypertension.

Option D: It is used for the treatment of schizophrenia symptoms.

" B

3394 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.

Option B: It is widely used for therapy of mild-to-moderate pain and arthritis.

Option C: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms.

Option D: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.

" D

5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.

Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

" D

3658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option B: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role.

Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

" D

5460875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: C(C(C(=O)[O-])N)C(=O)N

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.

Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.

Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

Option D: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia.

" D

3039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: COP(=O)(OC)OC=C(Cl)Cl

Question about this molecule: How can the molecule be used for therapeutic use

Option A: It can be used as therapy, both oral and intravenous, in human health and disease.

Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis.

Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.

Option D: It is used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations.

" D

3825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.

Molecule SMILES: CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O

Question about this molecule: How can the molecule be used for therapeutic use