sayyid14/MedMCQACancer · Datasets at Hugging Face

Unnamed: 0 int64 0 1.43k	question stringlengths 22 1.18k	opa stringlengths 1 160	opb stringlengths 1 159	opc stringlengths 1 253	opd stringlengths 1 166 ⌀	cop int64 0 3
1,000	A sublingual cancer in a 65 year old tobacco chew er has involved the mandible. The commando surgery has been planned. All of the following in removed in commando operation except -	Involved mandible	Oral cancer	Accessory nerve	Neck lymphnodes	2
1,001	Anal cancer is associated with	Human papilloma virus	EBV	HTLV-1	Polyoma virus	0
1,002	Intestinal polyps that can potentially grow into cancer:	Adenomatous polyp	Hyperplastic polyp	Juvenile polyp	Hamaomatous polyp	0
1,003	Lower end Esophageal cancer can be treated by:	Ivor Lewis Approach	Mc keown's Approach	Only Chemotherapy	Chemoradiotherapy	0
1,004	Which anticancer drug causes hypercoagulable syndrome?	5-FU	L-asparaginase	Melphalan	Carmustine	1
1,005	Immunity against cancer cells-	Basophills	Eosinophils	NK cells	Neutrophils	2
1,006	To control pain in long standing cancer cases, the recommended route of administration is:	i.v	Subcutaneous	Sublingual	Oral	3
1,007	A patient with obstructive jaundice due to pancreatic cancer might have all of the following clinical findings except	A palpable gallbladder	Pain is early in the course of the disease	Pulmonary metastasis	Thrombocytopenia	1
1,008	Due to advances in cancer treatment the prognosis of which of the following has become better?	Glioblastoma Multiforme	Esophageal Carcinoma	ALL in children	Cholangiocarcinoma	2
1,009	Stage 1A2 cervical cancer detected at 26 weeks of pregnancy. Next line of management is -	LSCS followed by Extrafascial hysterectomy at 28 weeks	Immediate CTRT	Classical c. section followed by Wertheim's hysterectomy at 30-32 weeks	MTP	2
1,010	Which of the following anticancer drugs can cause hypercoagulable state?	5-FU	L-asparaginase	Melphalan	Carmustine	1
1,011	Which of the following is the most effective intravesical therapy for superficial bladder cancer	Mitomycin	Adriamycin	Thiotepa	BCG	3
1,012	MC Occupational cancer is:-	Lung cancer	Skin cancer	Bladder cancer	Leukemias	1
1,013	Most common pre cancerous lesion is:	Leukoplakia.	Erythroplakia.	Nicotinic stomatitis.	OSMF.	0
1,014	A woman undergoes radical hysterectomy for Stage Ib Cervical cancer. On hisptopathological examination, it is found that cancer extends to lower body of uterus. What is the next management?	Chemotherapy	Radiotherapy	Repeat surgery for fuher disease reduction	Observation & follow up	3
1,015	A 63-year-old woman discovers a lump in her right breast. Mammography confirms the presence of a suspicious "lump," and a needle core biopsy is performed to determine whether the mass is malignant. The pathology repo confirms that the mass is indeed cancerous and that the tissue demonstrates amplification of the Her-2/neu oncogene. The gene product of Her-2/neu is what kind of protein?	GTPase	GTPase-activating protein	Nuclear transcription factor	Receptor tyrosine kinase	3
1,016	All of the following cancers are linked with HIV except-	Kaposi sarcoma	Urogenital cancer	Non Hodgkin	Adult T cell keukemia	3
1,017	Which of the following cancer is least associated with genetic and familial causes	Ovarian	Prostate	Lung	Breast	2
1,018	You are seeing a 62-year-old woman with a family history of breast cancer. She is worried about her future risk of breast cancer, since her mother died of breast cancer at the age of 63. Which of the following features is also a recognized risk factor for breast cancer?	early onset of menopause	early onset of menarche	late-life radiation exposure	multiparity	1
1,019	A 27-year-old woman requests a mammogram because both her mother and sister died of metastatic breast cancer before 40 years of age. Which of the following would add to this patient's risk factors for breast cancer?	Multiparity	High-fiber diet	Oral contraceptive use	BRCA1 mutation	3
1,020	Smoking is the cause of 85% of lung cancers that occurred within a group of smokers. This is an example of which of the following statistics?	Population attributable risk.	Odds ratio	Attributable risk	Relative risk	2
1,021	Which one of the following alkaloids is used as anti–cancer agent ?	Vincristine	Papaverine	Ephedrine	Atropine	0
1,022	Most common site for colon cancer is -	Caecum	Transversecolon	Rectosiigmoid	Ascendingcolon	2
1,023	Precancerous condition of the stomach is ?	Lipoma	Linitis plastica	Atrophic gastritis	Hyperacidity	2
1,024	In laryngeal cancer if anterior commissure is involved best management would be	Surgery	Chemotherapy	Radiotherapy	None of the above	2
1,025	Which of the following anticancer drugs are competitive inhibitors of tyrosine kinase -	Imatinib and suntinib	Letrozole	Bicalutamide	Fulvestrant	0
1,026	Cancer cells derive energy from -	Glycolysis	Oxidative metabolism	Increased mitochondria	null	0
1,027	A patient develops a form of lung cancer that spreads to occlude the thoracic duct. Edema involving which of the following sites might be expected as a potential complication?	Entire left side and right leg	Entire right side and left leg	Left arm only	Right arm and right half of head only	0
1,028	Most common site of pancreatic cancer is -	Head of pancreas	Neck of Pancreas	Tail of Pancreas	Body of pancreas	0
1,029	The most common precancerous lesion for oral malignancy is	chronic hypertrophic candidiasis	leukoplakia	dental ulcers	atrophic glossitis	1
1,030	Mamography for breast cancer is an example of which of the following?	Primordial	Primary	Secondary	Teiary	2
1,031	The most emetogenic anticancer drug is :	Cisplatin	Carboplatin	High dose cyclophosphamide	High dose methotrexate	0
1,032	Chemotherapy used after surgery or radiotherapy for cancer is termed as:	Combination chemotherapy	Adjuvant chemotherapy	Neoadjuvant chemotherapy	Concomitant chemotherapy	1
1,033	MACIS score used for prognosis of papillary cancer does not include?	Age	Size	Excision completion in surgery	Mitotic index	3
1,034	Descending order of cancer prevalance in males?	Lung > oral > pharynx > esophagus	Oral > lung > pharynx > esophagus	Pharynx > lung > oral > esophagus	Esophagus > oral > stomach > lung	1
1,035	A patient is diagnosed with cancer. Size of the lesion is found to be 5 cm in diameter and metastasis is found with single ipsilateral lymph node. The stage according to TNM staging is:	Stage 1	Stage 2	Stage 3	Stage 4	2
1,036	Boezomib is used for treatment of which cancer?	Multiple myeloma	Breast cancer	Tyrosine kinase inhibitor	Janus kinase inhibitor	0
1,037	which group of anticancer drugs Temozolomide belong to	Oral alkylating agent	Antitumor antibiotic	Antimetabolite	Mitotic spindle inhibitor	0
1,038	Following can cause endometrial cancer :	Metropathia hemorrhagica	Gynandroblastoma	Dysgerminoma	Teratoma	0
1,039	Prostate cancer is best diagnosed by?	Prostate specific antigen	Trans urethral ultra sound	FNAC of prostate gland	DRE	1
1,040	Which of the following is used to treat harmone responsive breast cancer	Cyptroterone acetate	Clomiphene citrate	Diethylstibestrol	Tamoxifen	3
1,041	Base population for a population based cancer registry is:-	1-2 million	1-3 million	1-5 million	2-7 million	3
1,042	Specific marker for prostatic cancer is	Prostate specific antigen	LDH	Chromogranin	CA 19-9	0
1,043	Which of the following has the highest potential of progression into cancer	Adenomatous polyp	Hyperplastic polyp	Juvenile polyp	Hamaomatous polyp	0
1,044	The risk of endometrial cancer is highest with the following histological pattern of endometrial hyperplasia:	Simple hyperplasia without atypia	Simple hyperplasia with atypia	Complex hyperplasia without atypia	Complex hyperplasia with atypia	3
1,045	Which of the following drugs is used in lung cancer is also used in ovarian carcinoma?	Cisplatin	Methotrexate	Cyclophosphamide	Dacarbazine	0
1,046	MC cancer due to Radiation :	Leukaemia	Bronchogenic Ca	Thyroid Ca	Breast cancer	0
1,047	Which of the following is least likely to be seen in occupational cancer?	Skin	Lungs	Liver	Bladder	2
1,048	A 65-year-old man presented with an episode of syncope. He said he felt dizzy during defecation and noticed gross bleeding in the pan. Fecal occult blood test done 3 months ago as a part of routine screening for colon cancer was negative. There is no history of recent weight loss. What is the likely colonoscopic finding?	Early stage carcinoma colon	Sigmoid diverticulitis	Microscopic colitis	Dilated mucosal and submucosal veins in the colon	3
1,049	A 41-year-old woman is diagnosed with CA Cervix. She has right hydronephrosis as evidenced by the intravenous pyelogram (IVP). The biopsy specimen confirms it is squamous cell cancer. Which of the following statements regarding this patient's condition is most accurate?	The best treatment for her is surgical excision.	The majority of cervical cancers are of adenomatous cell type.	Chemoradiation is the preferred treatment	Radical hysterectomy is an option in the therapy of this patient.	2
1,050	In case-control study there weve 35 cases of lung cancer and 82 controls (without lung cancer). Among cases 33 had positive history of smoking and among controls 55 had positive history of smoking. Odds ratio in this study is -	8	20	50	100	0
1,051	Which of the following is given to treat thrombocytopenia secondary to anti-cancer therapy and is known to stimulate progenitor megakaryocytes?	Filgrastim	Oprelvekin	Erythropoietin	Anagrelide	1
1,052	Which of the following anticancer drugs are competitive inhibitors of tyrosine kinase ?	Imatinib and suntinib	Letrozole	Bicalutamide	Fulvestrant	0
1,053	A 37-year-old woman presents to AIIMS OPD with a lump in the left breast.Family history is negative for breast cancer. On Examination the mass is rubbery, mobile, and nontender to palpation. No overlying skin changes and the axilla is negative for lymphadenopathy Ultrasound repo suggest a simple 1-cm cyst in the area of the palpable mass in the left breast. Most appropriate management of this patient?	Reassurance and re-examination	Fluoroscopically guided needle localization biopsy	Aspiration of the cyst with cytologic analysis	Immediate excisional biopsy,	0
1,054	A 56-year-old man presents with shortness of breath, fatigue, and edema. He has also noticed weight gain, abdominal discomfort, and distension. He has a prior history of lung cancer treated with radiotherapy to the chest. There is no history of liver or cardiac disease in the past. On examination, he has an elevated JVP, prominent y descent of neck veins, and positive Kussmaul sign. The heart sounds are normal. The CXR shows a normal cardiac silhouette and the ECG has low voltages.For the above patient with shortness of breath and peripheral edema, select the most likely diagnosis.	cardiac tamponade	constrictive pericarditis	restrictive cardiomyopathy	right ventricle myocardial infarction (RVMI)	1
1,055	An in-hospital workup of a 78-year-old hypeensive, mildly asthmatic man who is receiving chemotherapy for colon cancer reveals symptomatic gallstones. Preoperative laboratory results are notable for a hematocrit of 24% and urinalysis with 18 to 25 WBCs and gram-negative bacteria. On call to the operating room, the patient receives intravenous penicillin. His abdomen is shaved in the operating room. An open cholecystectomy is performed and, despite a lack of indications, the common bile duct is explored. The wound is closed primarily with a Penrose drain exiting a separate stab wound. On postoperative day 3, the patient develops a wound infection. Which of the following changes in the care of this patient could have decreased the chance of a postoperative wound infection?	Increasing the length of the preoperative hospital stay to prophylactically treat the asthma with steroids	Treating the urinary infection prior to surgery	Shaving the abdomen the night prior to surgery	Continuing the prophylactic antibiotics for 3 postoperative days	1
1,056	Which among the following is the most impoant preventive strategy of penile cancer?	HPV vaccination	Condom use	Neonatal circumcision	Cessation of smoking	2
1,057	Which of the following drugs is useful for treatment of advanced prostate cancer?	Ganirelix	Cetrorelix	Abarelix	Goserelin	3
1,058	Which of the following is an increased risk of breast cancer?a) Sclerosing adenosisb) Atypical hyperplasiac) Fibroadenomad) Florid hyperplasia	c	d	bd	ac	2
1,059	Which of the following is most common and most slowly growing thyroid cancer?	Papillary carcinoma	Follicular carcinoma	Anaplastic carcinoma	Medullary carcinoma	0
1,060	Peritoneal metastasis in colon cancer is staged as	M1a	M1b	M1c	M1d	2
1,061	Methotrexate is what class of anti cancer drug ?	Alkylating agents	Antimetabolites	Microtubule damaging agents	Topoisomerase inhibitors	1
1,062	Most common site for parasinus cancer is ?	Maxillary sinus	Frontal sinus	Ethmoidal sinus	Equal distribution in all sinuses	0
1,063	A 78-year-old patient presents with an advance cancer in the posterior mediastinum. The surgeons are in a dilemma as to how to manage the condition. Which of the following structures is most likely damaged?	Brachiocephalic veins	Arch of the azygos vein	Trachea	Hemiazygos vein	3
1,064	A patient with colorectal cancer develops septicemia complicated by endocarditis. You would expect the blood cultures to grow?	Streptococcus agalactiae	Streptococcus bovis	Streptococcus pneumoniae	Streptococcus pyogenes	1
1,065	Which one of the following is not associated with risk of cancer	Smoking	Alcohol	Chewing betel	Excess fibre	3
1,066	A thoracic surgeon removed the right middle lobar (secondary) bronchus along with lung tissue from a 57-year-old heavy smoker with lung cancer. Which of the following bronchopulmonary segments must contain cancerous tissues?,	Medial and lateral	Anterior and posterior	Anterior basal and medial basal	Anterior basal and posterior basal	0
1,067	Which of the following is the investigation of choice for assessment of depth of penetration and perirectal nodes in rectal cancer?	Trans rectal ultrasound	CT scan	Double contrast barium enema	MRI scan	3
1,068	Most common site for veebral cancer is ?	Cervical	Lumbosacral	Thoracic	Cervicodorsal	2
1,069	Dimpling in cancer breast happens due to	Edema	Infiltration of cooper's ligaments	Subdermal lymphangitis	Scaring	1
1,070	Least common quadrant of cancer breast	Superior Outer	Inferior Outer	Sub areolar	Lower inner quadrant	3
1,071	All of the following cancers commonly metastasize to the liver Except	Breast	Prostate	Colon	Pancreas	1
1,072	Commonest cancer in males is-	Lung	Prostate	Testis	Oral cavity	1
1,073	A 55-year-old woman is noted to be taking tamoxifen to help with breast cancer. She also complains of vaginal bleeding. Wof is the best explanation for vaginal bleeding	It is an estrogen antagonist in the breast and uterus, leading to loss of endometrial cells.	It has an antagonist effect on the breast but an agonist effect on the uterus.	It has estrogen agonist effect of the breast and uterus, thereby leading to endometrial hyperplasia.	It has no effect on the uterus, and the vaginal bleeding is caused by something else.	1
1,074	Which cancer develops in chronic ulcer	Malignant melanoma	Basal cell CA	Squamous cell CA	Kaposi sarcoma	2
1,075	True about dietary fibera) Soluble fiber ↑ metabolism of sugar in GITb) ↑bulk of stoolc) Only soluble fibers are included in dietd) ↑GI transit timee) Not prevention against colonic cancer	ac	a	ad	ab	3
1,076	Autosomal recessive, cancer syndrome in children is -	Neurofibromatosis	Ataxia-telongiectasia	Sturge-weber syndrome	Tuberous sclerosis complex	1
1,077	A patient with Barrett's esophagus underwent chromoendoscopy. Dye used in this patient for detection of cancer is:	Gentian violet	Toluidine blue	Hematoxylin and eosin	Methylene blue	3
1,078	"Early warning signs of Cancer" that public should be beware of include all except :-	Persistent cough	Lump or hard area in breast	Unexplained weight gain	Change in wa/mole	2
1,079	Cervical cancer is mostly caused by:	HPV 6	HPV 16	HPV 31	HPV 56	1
1,080	Anticancer drug that causes lung fibrosis is?	Bleomycin	Cisplatin	Fulvestrant	Tamoxifen	0
1,081	Which vitamin deficiency is found in gastric cancer patients?	Vitamin C	Vitamin B 12	Vitamin A	Vitamin D	1
1,082	Hand and foot syndrome is caused by which anticancer drug	Chloramphenicol	Cyclophosphamide	Mitomycin - C	Capecitabine	3
1,083	All of these familial conditions increase the risk of pancreatic cancer Except	Adenomatous polyposis coli	Hereditary non-polyposis colorectal cancer	Peutz-Jeghers syndrome	Hereditary breast and ovarian cancer	0
1,084	Cancer cells derive nutrition from :	Glycolysis	Oxidative phosphorylation	Increase in mitochondria	From a fast food joint	0
1,085	Histopatholoty of a lung cancer shows 'clara cells' probable diagnosis is -	Squamous cell cancer	Bronchio alveolar cancer	Large cell cancer	Papillary carcinoma	1
1,086	A 62-year-old woman undergoing chemotherapy for breast cancer presents with a 3-day history of fever and chest pain. Cardiac catheterization reveals a markedly reduced ejection fraction with normal coronary blood flow. A myocardial biopsy is obtained, and a PCR test for coxsackievirus is positive. Histologic examination of this patient's myocardium will most likely reveal an abundance of which of the followinginflammatory cells?	Eosinophils	Lymphocytes	Macrophages	Mast cells	1
1,087	A patient with cheek cancer has a tumor of 2.5 cm located close to and involving the lower alveolus. A single mobile ipsilateral lymph node measuring 6 cm is palpable. The TNM stage is:-	T1N1M0	T2N2M0	T2N1M0	T4N2M0	3
1,088	A 39-year-old man is admitted to the hospital with odynophagia. A barium swallow reveals an esophageal constriction at the level of the diaphragm. A CT scan and a biopsy further indicate the presence of an esophageal cancer. Which of the following lymph nodes will most likely be affected first?	Posterior mediastinal and left gastric	Bronchopulmonary	Tracheobronchial	Inferior tracheobronchial	0
1,089	A previously healthy 55-year-old man undergoes elective right hemicolectomy for a stage I (T2N0M0) cancer of the cecum. His postoperative ileus is somewhat prolonged, and on the fifth postoperative day his nasogastric tube is still in place. Physical examination reveals diminished skin turgor, dry mucous membranes, and ohostatic hypotension. Peinent laboratory values are as follows: Aerial blood gases: pH 7.56, PCO2 50 mm Hg, PO2 85 mm Hg. Serum electrolytes (mEq/L): Na + 132, K+ 3.1, Cl - 80; HCO3 - 42. Urine electrolytes (mEq/L): Na + 2, K+ 5, Cl - 6. What is the patient's acid-base abnormality?	Uncompensated metabolic alkalosis	Respiratory acidosis with metabolic compensation	Combined metabolic and respiratory alkalosis	Metabolic alkalosis with respiratory compensation	3
1,090	Assessment in suspected prostate cancer should include ALL EXCEPT ?	Transrectal ultrasound-guided biopsy (TRUS)	Cross-sectional MRI imaging	Bone scan	IVU	3
1,091	A most common subtype of thyroid cancer is?	Medullary carcinoma	Papillary carcinoma	Follicular carcinoma	Anaplastic carcinoma	1
1,092	All are familial breast cancer gene is all EXCEPT?	BRCA1	P53	P16	PTEN	2
1,093	Most common cancer that metastasizes to leptomeninges :	Lung cancer	Breast cancer	Prostate cancer	Ovarian cancer	1
1,094	Mutation not seen in diffuse type of gastric cancer?	E-cadherin	APC	p16	p53	1
1,095	Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except:	Nanocrystals exibit bright, photostable fluorescence	Nonocrystals have a narrow spectrum wavelength	Peak spectrum wavelength is tunable	Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra	3
1,096	The most common histological type of vulval cancer is?	Columnar cell carcinoma	Transitional cell carcinoma	Adenocarcinoma	Squamous cell carcinoma	3
1,097	A 28 years old Male is diagnosed with Lung cancer. Doctor has to explain diagnosis and prognosis to patient and family members. Technique to be used is:-	GATHER	SPIKES	Focus group discussion	Lecture	1
1,098	Cancer not associated with Human Papilloma virus	Cervical cancer	Testicular cancer	Vulval cancer	Oropharyngeal	1
1,099	A 40-year-old man notes a family history of colon carcinoma. He asks his physician how best to reduce his risk of developing this type of cancer. Which of the following dietary practices should he be advised to follow each day?	Consume more beef	Drink a glass of red wine	Eat more vegetables	Have a bowl of ice cream	2

1,000

A sublingual cancer in a 65 year old tobacco chew er has involved the mandible. The commando surgery has been planned. All of the following in removed in commando operation except -

Involved mandible

Oral cancer

Accessory nerve

Neck lymphnodes

2

1,001

Anal cancer is associated with

Human papilloma virus

EBV

HTLV-1

Polyoma virus

0

1,002

Intestinal polyps that can potentially grow into cancer:

Adenomatous polyp

Hyperplastic polyp

Juvenile polyp

Hamaomatous polyp

0

1,003

Lower end Esophageal cancer can be treated by:

Ivor Lewis Approach

Mc keown's Approach

Only Chemotherapy

Chemoradiotherapy

0

1,004

Which anticancer drug causes hypercoagulable syndrome?

5-FU

L-asparaginase

Melphalan

Carmustine

1

1,005

Immunity against cancer cells-

Basophills

Eosinophils

NK cells

Neutrophils

2

1,006

To control pain in long standing cancer cases, the recommended route of administration is:

i.v

Subcutaneous

Sublingual

Oral

3

1,007

A patient with obstructive jaundice due to pancreatic cancer might have all of the following clinical findings except

A palpable gallbladder

Pain is early in the course of the disease

Pulmonary metastasis

Thrombocytopenia

1

1,008

Due to advances in cancer treatment the prognosis of which of the following has become better?

Glioblastoma Multiforme

Esophageal Carcinoma

ALL in children

Cholangiocarcinoma

2

1,009

Stage 1A2 cervical cancer detected at 26 weeks of pregnancy. Next line of management is -

LSCS followed by Extrafascial hysterectomy at 28 weeks

Immediate CTRT

Classical c. section followed by Wertheim's hysterectomy at 30-32 weeks

MTP

2

1,010

Which of the following anticancer drugs can cause hypercoagulable state?

5-FU

L-asparaginase

Melphalan

Carmustine

1

1,011

Which of the following is the most effective intravesical therapy for superficial bladder cancer

Mitomycin

Adriamycin

Thiotepa

BCG

3

1,012

MC Occupational cancer is:-

Lung cancer

Skin cancer

Bladder cancer

Leukemias

1

1,013

Most common pre cancerous lesion is:

Leukoplakia.

Erythroplakia.

Nicotinic stomatitis.

OSMF.

0

1,014

A woman undergoes radical hysterectomy for Stage Ib Cervical cancer. On hisptopathological examination, it is found that cancer extends to lower body of uterus. What is the next management?

Chemotherapy

Radiotherapy

Repeat surgery for fuher disease reduction

Observation & follow up

3

1,015

A 63-year-old woman discovers a lump in her right breast. Mammography confirms the presence of a suspicious "lump," and a needle core biopsy is performed to determine whether the mass is malignant. The pathology repo confirms that the mass is indeed cancerous and that the tissue demonstrates amplification of the Her-2/neu oncogene. The gene product of Her-2/neu is what kind of protein?

GTPase

GTPase-activating protein

Nuclear transcription factor

Receptor tyrosine kinase

3

1,016

All of the following cancers are linked with HIV except-

Kaposi sarcoma

Urogenital cancer

Non Hodgkin

Adult T cell keukemia

3

1,017

Which of the following cancer is least associated with genetic and familial causes

Ovarian

Prostate

Lung

Breast

2

1,018

You are seeing a 62-year-old woman with a family history of breast cancer. She is worried about her future risk of breast cancer, since her mother died of breast cancer at the age of 63. Which of the following features is also a recognized risk factor for breast cancer?

early onset of menopause

early onset of menarche

late-life radiation exposure

multiparity

1

1,019

A 27-year-old woman requests a mammogram because both her mother and sister died of metastatic breast cancer before 40 years of age. Which of the following would add to this patient's risk factors for breast cancer?

Multiparity

High-fiber diet

Oral contraceptive use

BRCA1 mutation

3

1,020

Smoking is the cause of 85% of lung cancers that occurred within a group of smokers. This is an example of which of the following statistics?

Population attributable risk.

Odds ratio

Attributable risk

Relative risk

2

1,021

Which one of the following alkaloids is used as anti–cancer agent ?

Vincristine

Papaverine

Ephedrine

Atropine

0

1,022

Most common site for colon cancer is -

Caecum

Transversecolon

Rectosiigmoid

Ascendingcolon

2

1,023

Precancerous condition of the stomach is ?

Lipoma

Linitis plastica

Atrophic gastritis

Hyperacidity

2

1,024

In laryngeal cancer if anterior commissure is involved best management would be

Surgery

Chemotherapy

Radiotherapy

None of the above

2

1,025

Which of the following anticancer drugs are competitive inhibitors of tyrosine kinase -

Imatinib and suntinib

Letrozole

Bicalutamide

Fulvestrant

0

1,026

Cancer cells derive energy from -

Glycolysis

Oxidative metabolism

Increased mitochondria

null

0

1,027

A patient develops a form of lung cancer that spreads to occlude the thoracic duct. Edema involving which of the following sites might be expected as a potential complication?

Entire left side and right leg

Entire right side and left leg

Left arm only

Right arm and right half of head only

0

1,028

Most common site of pancreatic cancer is -

Head of pancreas

Neck of Pancreas

Tail of Pancreas

Body of pancreas

0

1,029

The most common precancerous lesion for oral malignancy is

chronic hypertrophic candidiasis

leukoplakia

dental ulcers

atrophic glossitis

1

1,030

Mamography for breast cancer is an example of which of the following?

Primordial

Primary

Secondary

Teiary

2

1,031

The most emetogenic anticancer drug is :

Cisplatin

Carboplatin

High dose cyclophosphamide

High dose methotrexate

0

1,032

Chemotherapy used after surgery or radiotherapy for cancer is termed as:

Combination chemotherapy

Adjuvant chemotherapy

Neoadjuvant chemotherapy

Concomitant chemotherapy

1

1,033

MACIS score used for prognosis of papillary cancer does not include?

Age

Size

Excision completion in surgery

Mitotic index

3

1,034

Descending order of cancer prevalance in males?

Lung > oral > pharynx > esophagus

Oral > lung > pharynx > esophagus

Pharynx > lung > oral > esophagus

Esophagus > oral > stomach > lung

1

1,035

A patient is diagnosed with cancer. Size of the lesion is found to be 5 cm in diameter and metastasis is found with single ipsilateral lymph node. The stage according to TNM staging is:

Stage 1

Stage 2

Stage 3

Stage 4

2

1,036

Boezomib is used for treatment of which cancer?

Multiple myeloma

Breast cancer

Tyrosine kinase inhibitor

Janus kinase inhibitor

0

1,037

which group of anticancer drugs Temozolomide belong to

Oral alkylating agent

Antitumor antibiotic

Antimetabolite

Mitotic spindle inhibitor

0

1,038

Following can cause endometrial cancer :

Metropathia hemorrhagica

Gynandroblastoma

Dysgerminoma

Teratoma

0

1,039

Prostate cancer is best diagnosed by?

Prostate specific antigen

Trans urethral ultra sound

FNAC of prostate gland

DRE

1

1,040

Which of the following is used to treat harmone responsive breast cancer

Cyptroterone acetate

Clomiphene citrate

Diethylstibestrol

Tamoxifen

3

1,041

Base population for a population based cancer registry is:-

1-2 million

1-3 million

1-5 million

2-7 million

3

1,042

Specific marker for prostatic cancer is

Prostate specific antigen

LDH

Chromogranin

CA 19-9

0

1,043

Which of the following has the highest potential of progression into cancer

Adenomatous polyp

Hyperplastic polyp

Juvenile polyp

Hamaomatous polyp

0

1,044

The risk of endometrial cancer is highest with the following histological pattern of endometrial hyperplasia:

Simple hyperplasia without atypia

Simple hyperplasia with atypia

Complex hyperplasia without atypia

Complex hyperplasia with atypia

3

1,045

Which of the following drugs is used in lung cancer is also used in ovarian carcinoma?

Cisplatin

Methotrexate

Cyclophosphamide

Dacarbazine

0

1,046

MC cancer due to Radiation :

Leukaemia

Bronchogenic Ca

Thyroid Ca

Breast cancer

0

1,047

Which of the following is least likely to be seen in occupational cancer?

Skin

Lungs

Liver

Bladder

2

1,048

A 65-year-old man presented with an episode of syncope. He said he felt dizzy during defecation and noticed gross bleeding in the pan. Fecal occult blood test done 3 months ago as a part of routine screening for colon cancer was negative. There is no history of recent weight loss. What is the likely colonoscopic finding?

Early stage carcinoma colon

Sigmoid diverticulitis

Microscopic colitis

Dilated mucosal and submucosal veins in the colon

3

1,049

A 41-year-old woman is diagnosed with CA Cervix. She has right hydronephrosis as evidenced by the intravenous pyelogram (IVP). The biopsy specimen confirms it is squamous cell cancer. Which of the following statements regarding this patient's condition is most accurate?

The best treatment for her is surgical excision.

The majority of cervical cancers are of adenomatous cell type.

Chemoradiation is the preferred treatment

Radical hysterectomy is an option in the therapy of this patient.

2

1,050

In case-control study there weve 35 cases of lung cancer and 82 controls (without lung cancer). Among cases 33 had positive history of smoking and among controls 55 had positive history of smoking. Odds ratio in this study is -

8

20

50

100

0

1,051

Which of the following is given to treat thrombocytopenia secondary to anti-cancer therapy and is known to stimulate progenitor megakaryocytes?

Filgrastim

Oprelvekin

Erythropoietin

Anagrelide

1

1,052

Which of the following anticancer drugs are competitive inhibitors of tyrosine kinase ?

Imatinib and suntinib

Letrozole

Bicalutamide

Fulvestrant

0

1,053

A 37-year-old woman presents to AIIMS OPD with a lump in the left breast.Family history is negative for breast cancer. On Examination the mass is rubbery, mobile, and nontender to palpation. No overlying skin changes and the axilla is negative for lymphadenopathy Ultrasound repo suggest a simple 1-cm cyst in the area of the palpable mass in the left breast. Most appropriate management of this patient?

Reassurance and re-examination

Fluoroscopically guided needle localization biopsy

Aspiration of the cyst with cytologic analysis

Immediate excisional biopsy,

0

1,054

A 56-year-old man presents with shortness of breath, fatigue, and edema. He has also noticed weight gain, abdominal discomfort, and distension. He has a prior history of lung cancer treated with radiotherapy to the chest. There is no history of liver or cardiac disease in the past. On examination, he has an elevated JVP, prominent y descent of neck veins, and positive Kussmaul sign. The heart sounds are normal. The CXR shows a normal cardiac silhouette and the ECG has low voltages.For the above patient with shortness of breath and peripheral edema, select the most likely diagnosis.

cardiac tamponade

constrictive pericarditis

restrictive cardiomyopathy

right ventricle myocardial infarction (RVMI)

1

1,055

An in-hospital workup of a 78-year-old hypeensive, mildly asthmatic man who is receiving chemotherapy for colon cancer reveals symptomatic gallstones. Preoperative laboratory results are notable for a hematocrit of 24% and urinalysis with 18 to 25 WBCs and gram-negative bacteria. On call to the operating room, the patient receives intravenous penicillin. His abdomen is shaved in the operating room. An open cholecystectomy is performed and, despite a lack of indications, the common bile duct is explored. The wound is closed primarily with a Penrose drain exiting a separate stab wound. On postoperative day 3, the patient develops a wound infection. Which of the following changes in the care of this patient could have decreased the chance of a postoperative wound infection?

Increasing the length of the preoperative hospital stay to prophylactically treat the asthma with steroids

Treating the urinary infection prior to surgery

Shaving the abdomen the night prior to surgery

Continuing the prophylactic antibiotics for 3 postoperative days

1

1,056

Which among the following is the most impoant preventive strategy of penile cancer?

HPV vaccination

Condom use

Neonatal circumcision

Cessation of smoking

2

1,057

Which of the following drugs is useful for treatment of advanced prostate cancer?

Ganirelix

Cetrorelix

Abarelix

Goserelin

3

1,058

Which of the following is an increased risk of breast cancer?a) Sclerosing adenosisb) Atypical hyperplasiac) Fibroadenomad) Florid hyperplasia

c

d

bd

ac

2

1,059

Which of the following is most common and most slowly growing thyroid cancer?

Papillary carcinoma

Follicular carcinoma

Anaplastic carcinoma

Medullary carcinoma

0

1,060

Peritoneal metastasis in colon cancer is staged as

M1a

M1b

M1c

M1d

2

1,061

Methotrexate is what class of anti cancer drug ?

Alkylating agents

Antimetabolites

Microtubule damaging agents

Topoisomerase inhibitors

1

1,062

Most common site for parasinus cancer is ?

Maxillary sinus

Frontal sinus

Ethmoidal sinus

Equal distribution in all sinuses

0

1,063

A 78-year-old patient presents with an advance cancer in the posterior mediastinum. The surgeons are in a dilemma as to how to manage the condition. Which of the following structures is most likely damaged?

Brachiocephalic veins

Arch of the azygos vein

Trachea

Hemiazygos vein

3

1,064

A patient with colorectal cancer develops septicemia complicated by endocarditis. You would expect the blood cultures to grow?

Streptococcus agalactiae

Streptococcus bovis

Streptococcus pneumoniae

Streptococcus pyogenes

1

1,065

Which one of the following is not associated with risk of cancer

Smoking

Alcohol

Chewing betel

Excess fibre

3

1,066

A thoracic surgeon removed the right middle lobar (secondary) bronchus along with lung tissue from a 57-year-old heavy smoker with lung cancer. Which of the following bronchopulmonary segments must contain cancerous tissues?,

Medial and lateral

Anterior and posterior

Anterior basal and medial basal

Anterior basal and posterior basal

0

1,067

Which of the following is the investigation of choice for assessment of depth of penetration and perirectal nodes in rectal cancer?

Trans rectal ultrasound

CT scan

Double contrast barium enema

MRI scan

3

1,068

Most common site for veebral cancer is ?

Cervical

Lumbosacral

Thoracic

Cervicodorsal

2

1,069

Dimpling in cancer breast happens due to

Edema

Infiltration of cooper's ligaments

Subdermal lymphangitis

Scaring

1

1,070

Least common quadrant of cancer breast

Superior Outer

Inferior Outer

Sub areolar

Lower inner quadrant

3

1,071

All of the following cancers commonly metastasize to the liver Except

Breast

Prostate

Colon

Pancreas

1

1,072

Commonest cancer in males is-

Lung

Prostate

Testis

Oral cavity

1

1,073

A 55-year-old woman is noted to be taking tamoxifen to help with breast cancer. She also complains of vaginal bleeding. Wof is the best explanation for vaginal bleeding

It is an estrogen antagonist in the breast and uterus, leading to loss of endometrial cells.

It has an antagonist effect on the breast but an agonist effect on the uterus.

It has estrogen agonist effect of the breast and uterus, thereby leading to endometrial hyperplasia.

It has no effect on the uterus, and the vaginal bleeding is caused by something else.

1

1,074

Which cancer develops in chronic ulcer

Malignant melanoma

Basal cell CA

Squamous cell CA

Kaposi sarcoma

2

1,075

True about dietary fibera) Soluble fiber ↑ metabolism of sugar in GITb) ↑bulk of stoolc) Only soluble fibers are included in dietd) ↑GI transit timee) Not prevention against colonic cancer

ac

a

ad

ab

3

1,076

Autosomal recessive, cancer syndrome in children is -

Neurofibromatosis

Ataxia-telongiectasia

Sturge-weber syndrome

Tuberous sclerosis complex

1

1,077

A patient with Barrett's esophagus underwent chromoendoscopy. Dye used in this patient for detection of cancer is:

Gentian violet

Toluidine blue

Hematoxylin and eosin

Methylene blue

3

1,078

"Early warning signs of Cancer" that public should be beware of include all except :-

Persistent cough

Lump or hard area in breast

Unexplained weight gain

Change in wa/mole

2

1,079

Cervical cancer is mostly caused by:

HPV 6

HPV 16

HPV 31

HPV 56

1

1,080

Anticancer drug that causes lung fibrosis is?

Bleomycin

Cisplatin

Fulvestrant

Tamoxifen

0

1,081

Which vitamin deficiency is found in gastric cancer patients?

Vitamin C

Vitamin B 12

Vitamin A

Vitamin D

1

1,082

Hand and foot syndrome is caused by which anticancer drug

Chloramphenicol

Cyclophosphamide

Mitomycin - C

Capecitabine

3

1,083

All of these familial conditions increase the risk of pancreatic cancer Except

Adenomatous polyposis coli

Hereditary non-polyposis colorectal cancer

Peutz-Jeghers syndrome

Hereditary breast and ovarian cancer

0

1,084

Cancer cells derive nutrition from :

Glycolysis

Oxidative phosphorylation

Increase in mitochondria

From a fast food joint

0

1,085

Histopatholoty of a lung cancer shows 'clara cells' probable diagnosis is -

Squamous cell cancer

Bronchio alveolar cancer

Large cell cancer

Papillary carcinoma

1

1,086

A 62-year-old woman undergoing chemotherapy for breast cancer presents with a 3-day history of fever and chest pain. Cardiac catheterization reveals a markedly reduced ejection fraction with normal coronary blood flow. A myocardial biopsy is obtained, and a PCR test for coxsackievirus is positive. Histologic examination of this patient's myocardium will most likely reveal an abundance of which of the followinginflammatory cells?

Eosinophils

Lymphocytes

Macrophages

Mast cells

1

1,087

A patient with cheek cancer has a tumor of 2.5 cm located close to and involving the lower alveolus. A single mobile ipsilateral lymph node measuring 6 cm is palpable. The TNM stage is:-

T1N1M0

T2N2M0

T2N1M0

T4N2M0

3

1,088

A 39-year-old man is admitted to the hospital with odynophagia. A barium swallow reveals an esophageal constriction at the level of the diaphragm. A CT scan and a biopsy further indicate the presence of an esophageal cancer. Which of the following lymph nodes will most likely be affected first?

Posterior mediastinal and left gastric

Bronchopulmonary

Tracheobronchial

Inferior tracheobronchial

0

1,089

A previously healthy 55-year-old man undergoes elective right hemicolectomy for a stage I (T2N0M0) cancer of the cecum. His postoperative ileus is somewhat prolonged, and on the fifth postoperative day his nasogastric tube is still in place. Physical examination reveals diminished skin turgor, dry mucous membranes, and ohostatic hypotension. Peinent laboratory values are as follows: Aerial blood gases: pH 7.56, PCO2 50 mm Hg, PO2 85 mm Hg. Serum electrolytes (mEq/L): Na + 132, K+ 3.1, Cl - 80; HCO3 - 42. Urine electrolytes (mEq/L): Na + 2, K+ 5, Cl - 6. What is the patient's acid-base abnormality?

Uncompensated metabolic alkalosis

Respiratory acidosis with metabolic compensation

Combined metabolic and respiratory alkalosis

Metabolic alkalosis with respiratory compensation

3

1,090

Assessment in suspected prostate cancer should include ALL EXCEPT ?

Transrectal ultrasound-guided biopsy (TRUS)

Cross-sectional MRI imaging

Bone scan

IVU

3

1,091

A most common subtype of thyroid cancer is?

Medullary carcinoma

Papillary carcinoma

Follicular carcinoma

Anaplastic carcinoma

1

1,092

All are familial breast cancer gene is all EXCEPT?

BRCA1

P53

P16

PTEN

2

1,093

Most common cancer that metastasizes to leptomeninges :

Lung cancer

Breast cancer

Prostate cancer

Ovarian cancer

1

1,094

Mutation not seen in diffuse type of gastric cancer?

E-cadherin

APC

p16

p53

1

1,095

Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except:

Nanocrystals exibit bright, photostable fluorescence

Nonocrystals have a narrow spectrum wavelength

Peak spectrum wavelength is tunable

Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra

3

1,096

The most common histological type of vulval cancer is?

Columnar cell carcinoma

Transitional cell carcinoma

Adenocarcinoma

Squamous cell carcinoma

3

1,097

A 28 years old Male is diagnosed with Lung cancer. Doctor has to explain diagnosis and prognosis to patient and family members. Technique to be used is:-

GATHER

SPIKES

Focus group discussion

Lecture

1

1,098

Cancer not associated with Human Papilloma virus

Cervical cancer

Testicular cancer

Vulval cancer

Oropharyngeal

1

1,099

A 40-year-old man notes a family history of colon carcinoma. He asks his physician how best to reduce his risk of developing this type of cancer. Which of the following dietary practices should he be advised to follow each day?

Consume more beef

Drink a glass of red wine

Eat more vegetables

Have a bowl of ice cream

2