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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | synthesis pathways as a key signaling protein. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | At the beginning of menstruation, hormonal changes may play a significant role in increasing atopic dermatitis' severity during puberty and adolescence. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Different forms of immune function entail different physiological profiles, each implying unique temporal and absolute patterns of energy use (5, 39). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, the study was conducted in three different regions in Finland, which reduces selection bias at the population level. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In a series reporting on pain assessment and documentation at our institution, we found the rate of documentation of pain intensity scores had increased between 2000 and 2006 from 77% to over 95%. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Once mass was accounted for there was no significant difference in prevalence between males or females. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings provide further evidence that over-nutrition in utero may lead to high-risk BMI trajectories during early childhood. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | During routine CPB cases, it is, in most centers, possible to have laboratory blood gas analyses performed whenever necessary, but in emergency surgery, often performed off normal working hours with little or no extra personnel available for errand running, reliable in-line monitoring is a valuable tool for the perfusionist in the acid-base management of the perfusion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pulsatile cortisol infusion was more inhibitory of pulsatile ACTH secretion than continuous cortisol infusion, specifically as a function of E2 concentrations in postmenopausal women. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the latter case, it represents interaction between instrumental model-based and instrumental model-free processes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | External lesions were only found on adult voles of mass >17 g, with prevalence generally increasing with the age of individuals. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | After adjustment for FN-BMD, the effect sizes for the associations between the GRS63 and hip fractures (−64%) and all fractures (−50%) were substantially reduced and for hip fracture no longer significant. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The top significant genes identified included DEF8, DBNDD1, SPATA33 and MC1R. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The limitation of this study, however, is its retrospective design and the results here should, ideally, be confirmed by subsequent larger prospective studies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Commonly, methylation of the promoter or the 5′UTR of a gene is just the first step of a long series of events leading to gene silencing. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A second statistical issue, common to all scans for variant associations, is that each of the many GSVs detected in even a small cohort is the subject of a separate independent hypothesis, so that substantial multiple testing correction of the significance threshold or rigorous control of the false discovery rate (FDR) is required if a large type I error rate is to be avoided. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In these trials, patients showed systemic reactions rates ranging from of 0·28–46·6% and local adverse reactions rates ranging from 0·66 to 66·6%. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | When acute pain is not well managed, the patient is at greater risk of chronic persistent pain (Joshi & Ogunnaike, 2005). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Several studies have found that the overweight and obesity are the risk of hypertension [17,18]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both of them could be considered to be of the cluster type, as they involved two separate injections at the first visit. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, a novel results of this study was the robust association between snorting/gasping and stroke risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although the mechanism is still not well-understood, it is believed that this may occur through increased transfer of maternal energy substrates, such as glucose, lipids and amino acids to the fetus28, 42, with the combined increase in all fuels likely contributing to the development of high-risk trajectories during early childhood28. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In Liksul, the SLC4A1Δ27 and GYPCΔex3 allele frequencies were high, thus allowing us to examine the interactions of both band 3 and glycophorin C genotypes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interactions among HLA-restricted T lymphocytes, B lymphocytes, natural killer cells, and cytokines influence immune response to viral infection. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, Krause (2004) showed that attitudes towards prayer may be important variables relating to psychological outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Katherine et al reported no association between walking distance to fruit and vegetable retailers with the risk of prediabetes/diabetes in Australia (Baldock et al, 2018). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the pneumoperitoneum period, the PaO2/FiO2 ratio in the E group was better than that in the C group, although no significant difference was ascertained in both groups. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The present study assessed the immunological performance of HBV vaccination after 2 decades since the beginning of the national immunization program, updating the state of the art on this relevant issue in Italy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pure retrieval anomia occurred in the presence of a putative object–word interface that appeared functional enough to support the accurate matching of the unnamed object to its name during the pointing tasks. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The survey was large in scale and relied on a complex design including multistage sampling, stratification, and clustering. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Understanding the molecular genetic basis of a common disease casts light on the biological factors involved in disease initiation and progression, and may suggest new treatment strategies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This exploratory study provides new evidence on neighborhood environment attributes associated with active commuting in India, a rapidly urbanizing LMIC context. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additional long-term longitudinal studies are needed to establish causality. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A higher density of highly processed and take-away food vendors was associated with an increase in BMI/waist circumference and blood pressure. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Investigations on semantic dementia have tended to attribute the naming failures in patients with anterior temporal lobe atrophy to impaired general knowledge of the object rather than a specific impairment of verbal retrieval (Snowden et al, 1989; Lambon Ralph et al, 2001; Adlam et al, 2006). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Greater ACTH suppression by cortisol in women given E2 differs diametrically from most data obtained in animal studies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The aminoglycoside use patterns at our institution suggest that a significant proportion of these patients are likely critically ill, as aminoglycoside prescribing outside the intensive care unit is uncommon. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this kind of model, network hubs have a ‘transmodal’ architecture where multi-modal (though not pan-modal) convergence does take place but in the presence of domain-specificity, and where inter-network integration is more distributed than confluent (Mesulam, 1990, 1998). |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A psychological profile assessment can help a multidisciplinary gender dysphoria team to detect potential psychopathological factors of vulnerability, changes and stabilization over time of the abilities of adaptability of the individual. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Accelerated CVD leads to debilitating morbidity in HGPS, and culminates in mortality from myocardial infarction or stroke at an average at of 13 years 6. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These include localization of the site of attachment of the mass as well as the extent of involvement, reliable estimation of tumor size, and identification of adherent or coincident thrombus. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As we did not see any side effects, the administration of theophylline is safe even in critical ill patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, our data showed a strong correlation between self-reported pre-pregnancy weight and measured booking weight (ρ = 0.96), and sensitivity analyses using booking BMI as a predictor showed similar observations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Other successful navigation interventions have taken place over six months and have included full-time navigators. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, E-selectin is considered to play a central role in hematogenous metastasis (16–18). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The support for a first-grade inoculation effect was inconsistent and inconclusive. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As the mean concentration of SHBG is lower in the cases, one might expect higher percentages of non protein-bound oestradiol in the cases than in the controls, as previously reported in the Guernsey cohort (Moore et al, 1986). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The most common arch forms were narrow tapered followed by narrow ovoid in both males and females and in all the 3 Classes of malocclusion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | On the contrary, Nfatc1nuc mice (DT) fed doxycycline chow for 4 months developed podocyte loss, glomerulosclerosis, elevated serum creatinine, and increased collagen staining. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our inconclusive rate was high overall at 13.1% but differed by screening location from as low as 3.6% to as high as 25%, possibly reflecting both a technical learning curve as well as site specific difficulties in creating an acceptable screening environment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In fact, in cases where BMD is not known, a BMD measurement is more informative than an analysis of the SNPs included in the GRSs. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In their multicenter clinical evaluation study they found that the CDI overestimated the pO2 values when compared to their standard, and the authors speculated that the discrepancy could be caused by the methodology of the analyzers. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | According to our current analysis, trabectedin-related liver enzymes elevations do not affect the progression-free or overall survival of patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The 3.0T imaging and contrast-enhancement combined with inversion-recovery preparation allow high contrast between blood and background tissue. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As the vibrating sandals were a simple prototype, a different design may elicit greater reductions in gait variability. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, over the last two decades we have gained enough experience to provide versatile and high-quality oncological surgery using the minimally invasive approach. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our review of 300 consecutive primary acetabular replacements mixing ZweymuÈller grit-blasted screw rings of first and second generation showed, with loosening as the endpoint, a 99.1% survival rate at the 7 to 8 year follow-up [4]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Among the vascular adhesion molecules, E-selectin is essential for recruitment of inflammatory cells to damaged tissues (31), and it enables circulating tumor cells to roll and tether on the endothelium. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A hand-held metal detector (such as those used at airports) might help detect pacemakers in the mortuary. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There are several possible reasons for the apparent difference between children and adults: it may reflect population differences (the child carriers of the GSV were from France and the UK, the adults primarily from Nordic countries); it may reflect cohort ascertainment, for instance that the child cohorts did not include overweight or mildly obese subjects – it is notable, however, that the deletion was not reported at a comparable frequency in cohorts of children with common obesity [16]; it may reflect a genuine attenuation of the effect of the deletion in adults, so that impact of the GSV on obesity becomes less pronounced with increasing age; or the severe obesity observed in children may have been triggered by an aspect of the modern obesogenic environment that was experienced to a lesser degree by older subjects. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | First, buffering with bicarbonate helps maintain a neutral pH and therefore reduces oxygen consumption of the kidneys 30. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This can be achieved by explicitly expanding a model that represents the underlying structure of the environment, followed by calculating the expected value of each plan. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Mortara et al. reported the relationship between the level of NGAL at admission and the kidney function, defined as baseline creatinine and eGFR [15]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The costs to the wider Indian economy from a heavy reliance on the private car as a mode of transportation run into tens of billions of dollars every year [23,83]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Travel history for all patients in these two PO10s was unavailable, and comparison with the genomes collected from EnteroBase did not reveal any links to other countries. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We observed a lower likelihood of having new type 2 diabetes and a lower 2 h glucose concentration in ECPs than in NECPs. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, there is a rationale to prevent adenosine-induced vasoconstriction in patients at risk for developing CIN. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Clearly, more empirical research on reduction as a goal of treatment is warranted. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The hypothesis that hay lorries passing through the docks could have caused the outbreak was known to a number of employees before they completed the questionnaire, and this finding may therefore be a result of diagnostic suspicion bias (41). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Reduction attempts were more common than abstinence attempts in our self-changers. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This also poses a problem for replication – the failure to detect some GSVs in our cohorts may reflect low frequencies in the populations from which they were drawn. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While our predominantly white sample was appropriate for studying Appalachians, we are unable generalize results to other groups. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Within India, this study complements the objectives of on-going national government schemes in India, such as the Smart Cities Mission (http://smartcities.gov.in/content/), the Swachh Bharat Mission (http://www.swachhbharaturban.in/sbm/home/), and the Atal Mission for Rejuvenation and Urban Transformation (AMRUT, https://amrut.gov.in/), in aspects of urban land use and health promotion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We lacked detailed information on occupation and socioeconomic status, but exploratory analyses did not reveal any differences in intervention effect by educational attainment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Object knowledge impairments therefore appear to play a distinctly less causative role than word comprehension impairments in the associative naming failures that follow left anterior temporal lobe atrophy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | in 5 %O2 vs. 44.7% in 20% O2). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This affirms the need to distinguish between the two forms of pain outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Compared to the Alloclassic-SL stem implantation, insertion of the ZweymuÈller Alloclassic-CSF screw ring is technically easy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We believe these advantages outweigh its relative complexity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Patients with stronger beliefs in Specific-Necessity may recognise the potential benefits and role of analgesics in protecting their present and future oral health against deterioration. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We obviously cannot rule out the possibility that the surviving anterotemporal neurons in Patients S1–S11 might contain an amodal hub though it is unlikely that the neurodegenerative process in these patients would have selectively destroyed the neurons that lack such amodal properties. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, due to low numbers, and hence broad confidence intervals, for individuals of mass >30 g in weight, it is not possible to confirm whether risk of TB increases in the heaviest age classes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Dosage and time of administration vary, but especially in older studies, the statin was administered between 6 and 12 h before CM. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Being overweight itself may constitute a barrier to PA [19]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Parkinsonian rats showed impairment in the oral processing stage of deglutition, evident by the increase in aberrant tongue movement without successful bolus transit to the pharynx. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This result supports the findings of several previous studies, Bishara et al,7 Al-Khateeb and Abu Alhaija,10 and Uysal et al17 Even longitudinal studies found that the arch width in males was greater than in females 18. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Similar genetic profiles have previously been reported for NDM-producing E. coli ST410 isolates obtained from patients in Denmark and the United Kingdom (21), indicating either similar travel patterns by inhabitants of the two countries or direct transmission between the countries. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However this practice is no longer in place due to funding issues. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Furthermore, hypertensive patients who normalized their body mass index can largely improve BP level and a number of metabolic and hormonal parameters [19,20]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | First, PWVcf was dramatically elevated overall. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The current study showed that hysterectomy was safe and feasible 4 weeks after conization, with both decreased postoperative infection and lower use of antibiotics, which may be because the tissues damaged by cervical conization had already been repaired by this period. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Optimal postoperative pain relief both at rest and with movement have recently been emphasized to facilitate rehabilitation and timely discharge from the hospital (Joshi & Ogunnaike, 2005). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Plasma NGAL of CRS Type 5 patients was higher when compared to controls but there was not a statistic relationship between this parameter and outcome. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The CLU rs1113600 T allele is associated with reduced risk of AD [Harold et al 2009; Lambert et al 2009], and was associated with a higher composite cognitive score for both men and women 92-93 years of age at enrollment in a Danish birth cohort study, while the effect of variation in PICALM (rs3851179) [Harold et al 2009] was restricted to males [Mengel-From et al 2011]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However the GRS63 cannot replace the BMD measurements as FN-BMD was superior to the GRS63 in the discrimination and reclassification of fracture risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Transmodal areas receive input from the highest synaptic levels of sensory-fugal processing hierarchies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While significantly increased colonic permeability was not observed, the cumulative urine excretion of lactulose at 8–24 h was increased (P = 0.10). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This is a retrospective review and patients with prostate cancer are not included, although it is well documented that prostate cancer is among the gamut of tumours carrying the highest risk of developing bone metastases. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This indicates that, under walnut consumption, the gut microbiota showed a slightly lower diversity than under the control diet; however, this difference was not significant. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Its use seemed not sensible in our patients as we intended to cover emergency procedures as well as critically ill patients on the ICU. |