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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Disadvantages related to THA surgery, such as dislocation rates and revision rates, are relevant to include in the investigation of potential differences between the 2 surgical approaches, but this would require a longer follow-up and a study design with a larger sample size (Jolles and Bogoch 2004). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further studies are needed to give the complete and true picture of the pathogenicity and fitness of ST410. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As with any retrospective investigation, there exist several limitations associated with our analysis that may impact clinical translation. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, establishment of an institutional biorepository for banking of serum, urine, stool, and tissue samples should be considered — only with the committed and coordinated efforts of the entire health-care team will we find answers to the many questions that remain. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings indicated that DICER1 rs3742330 AG heterozygotes were associated with an increased risk of CRC. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings suggest that different BMIz trajectories in the first 2 years reflect differential changes in body composition (fat vs lean mass) and are more predictive of body composition and obesity in later childhood than a single time point assessment of BMIz at 2 years. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It’s not a matter of skin color, it’s only a matter of clean, how clean you are, how willing to be a part of this, just your willingness to be clean is all that matters.” |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the study did not focus on changes in these components, particularly since the study relied on self-reported food records making it difficult to correctly estimate phytonutrient intake. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The ABL 800 flex warms the blood to 37°C before analysis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although there is certain similarity in clinical manifestations of hepatitis induced by these viruses and creating background for subsequent development for LC and HCC, their molecular organization, replication strategy and functions of constituent proteins are different. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, this method is not widely performed because it is relatively difficult in practice and the cost is high. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | One potential limitation of this functional annotation study was that we had no access to the whole genome-wide set of summary statistics. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The relationship between age of individuals and the prevalence of macro-lesions (based on post-mortem) was stronger than that between age and prevalence for individuals that were lesion negative and culture positive. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Second, our sample size was moderate (201 participants) and we might have missed some true associations because of lack of statistical power. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The finding of greater effect on those with elevated DBP could relate to meticulous focus by the intervention MTM pharmacists on both SBP and DBP when considering further treatments. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | One retrospective study recommended that patients with localized NTM lung disease be considered for pulmonary resection as early as possible (14). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The maximum acceptable bupivacaine infusion rate is 0.4 mg/kg/hr for older children and adults and 0.2 mg/kg/hr for infants (Verghese & Hannallah, 2005; Yaster, Tobin, & Kost-Byerly, 2003). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although the proposal has been made that the amodal semantic hub may actually reside in the anterior fusiform gyrus, which was not a major site of peak atrophy in most of our patients, there are also cogent reasons for questioning such a location (Snowden et al, 2004; Mion et al, 2010). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The same applied to the secondary outcomes except for limping, where patients in the PA group improved more than the patients in the LA group. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Because of technical differences between LPN and RAPN, we expected to observe the difference in postoperative pain intensity between the 2 modes of surgery. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, with respect to DICER1 related cancers, several studies have suggested that loss of function or mutation of DICER1 may affect stem cell proliferation, differentiation, and cell fate and induce embryonal or blastoma carcinomas17,51,52. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the former case, our algorithm represents a collaborative interaction between instrumental model-based and Pavlovian processes [24]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Release of separase in this process also activates CDC14 in a positive-feedback loop, in which CDC14 dephosphorylates securin for continual ubiquitination by the APC [18]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We do not know of other studies of how quickly cannabis users trying to quit on their own relapse. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In Korea, according to Lee et al., as monthly income and education status increase, there was more severe atopic dermatitis populations observed [42]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There are various ways that information can be obtained about cancer and early diagnosis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Surgical procedures induce postoperative complications and early recurrence after surgery by releasing inflammatory cytokines, such as IL-1β and TNF-α (1, 2). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Contextual skills comprise practical matters such as planning meals, considering what food is good for oneself and having regular meals [8]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the steep relapse observed in this study is similar to that of self-quitting in tobacco smokers (Hughes, Keely, & Naud, 2004). |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | To sum up, it may be asserted that, if in individual cases ventral spondylodesis is feasible, this method should be used. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Remarkably, when only LOS variables were included in the regression model and covariates were controlled for, all but one measure (DCL) were significant DHI predictors (Model 3, Tables 3 and and4).4). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In four patients fractures occurred after they had started on a gluten-free diet. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Other studies by Kwon et al18 and Giles et al17 also identified four BMI trajectories with similar patterns; those studies utilized a different technique known as group-based trajectory modelling, however, which assumes no within-class variation (i.e., variance in each subgroup is fixed to zero)8. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although problematic for the identification of an association, we nevertheless note that the existence of multiple different GSVs may be of great utility in dissecting a locus whose association has been conclusively demonstrated. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Patients who reported lower salt intake may have been more physiologically responsive to treatment with diuretics, a mainstay of treatment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Of course, the prayer–health dynamic can be a reciprocal process whereby higher levels of pain lead to higher use of prayer which, in turn, decreases the detrimental effect of pain on daily life. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Li et al. [13] showed that surgery time, blood loss, conversion to laparotomy, and preoperative morbidity after posterior radical hysterectomy performed following conization varied with the time interval, and indicated that the appropriate time interval was 6 weeks after conization. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Local production of angiogenin is strongly suggested by our finding that angiogenin is released in large amounts by synovial fibroblasts from joints with active or chronic synovitis (Figs 3, ,4).4). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Control Measures Risk assessment and risk management was undertaken by identifying groups of persons at different levels of risk and providing relevant advice, temporarily stopping work in the area of the building considered at greatest risk, and following identified patients with Q fever. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | For the treatment of M. abscessus lung disease, combined intravenous antibiotic therapy including amikacin and cefoxitin for 2-4 weeks for clinical and microbiologic improvement was recommended in addition to the oral antibiotics, including clarithromycin (or azithromycin) (citation). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additionally, among the Danish ST410 isolates, 20/49 (41%) were from bloodstream infections, which may qualify for severe infections, and show a potential for enhanced pathogenicity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Epigenetic modifications in response to environmental exposures at these critical periods are often subtle initially and even though they do not lead to phenotypic changes at the time of exposure, they may lead to increased risk of dysfunction and disease later on in life [17]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The prevalence found in this study is similar to the prevalence of self-medication (30%) reported in previous study by Simon et al, [10], and lower prevalence than a study by Jain et al, [11], where approximately three-quarter of the participants (72%) practised self-medication. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In a study of more than 2,000 older white participants (median age at first assessment 77 years) who were assessed longitudinally for progression to MCI or AD the CLU rs11136000 risk allele was associated with lower scores at baseline on a test of paragraph delayed recall from the Wechsler Memory Scale-Revised Logical Memory subtest but not with 5-year decline in verbal memory while no associations were found for the other eight loci [Carrasquillo et al 2015]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although this was not a primary end point, our study was sufficiently powered to detect a clinically meaningful difference in the inflammatory cell infiltrate in the two groups on the basis of HLA-DQ status. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | An epidemiological link was found among patients P2 to P8. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, information regarding valvular function, wall motion, and other concomitant cardiac disease can be obtained. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Here we show for the first time in a relatively large cohort of subjects that there is a spectrum of peripheral immunophenotypic abnormalities in PAD, ranging from those present in AFM across those found in IgGSD and IPH patients to those in CVID patients, with the differences being most notable in naïve and memory T- and B-lymphocyte subsets. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, there were no significant differences in opioid requirements between the 2 groups from POD 1 to POD 4. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the rat model, we have also shown biting and chewing deficits in a 6-OHDA model in rats while eating pasta [71]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These constraints disproportionately affected poorer households, but were a problem for less poor households as well. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These patients continued to receive additional attention to their elevated BP during the study as a result of quality improvement efforts, while patients without diabetes did not. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additionally, we measured seminal plasma HIV-1 RNA and did not quantify cell-associated virus. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Bone scanning is the most useful study in assessing patients with suspected metastatic skeletal disease because of its ability to detect asymptomatic disease approximately 4 months on average before a lesion can be identified by plain radiography [citation]. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Anticoagulation for VTE should be continued for 3 to 6 months. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Second, mediation analyses showed that the cognitive activity of positive re-appraisal mediated the relationship between prayer and pain tolerance. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A potential pitfall of our study is that patient participants were not selected on the basis of a history suggestive of gluten sensitivity or a prior response to gluten withdrawal. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study demonstrates that parallels can be drawn between the phylogeny and emergence of fluoroquinolone and ESBL resistance (CTX-M-15) in ST131 and ST410. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | First, the function of DICER1, influenced by rs3742330 plays a pivotal role in CRC tumorigenesis by altering the expression of miRNA-related oncogenic pathways underlying cellular transformation, such as proliferation, apoptosis, invasion, and metastasis67. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further studies will be needed in selected pathophysiologies to further generalize sex differences in cortisol feedback. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Because there is no biomarker that can be used to confirm the clinical diagnosis and there is often a mixture of vascular and AD pathology found on autopsy [Fernando et al 2004; Lopez et al 2003b; Schneider et al 2007], genetic studies of AD based on case status may be complicated by substantial phenotypic heterogeneity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Hysterectomy, one of the most common gynecologic surgical procedures, can be performed via vaginal, abdominal, or laparoscopic approaches [citation]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, we analyzed the DICER1 rs3742330 genotype to determine the association between lutein/zeaxanthin intake and CRC risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the highly complex nature of cholesterol-mediated cell injury in vivo requires further investigation, as other studies yielded conflicting results showing either protective or detrimental effects of esterified cholesterol accumulation in atherosclerotic phenotypes (56). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finding optimal or near optimal actions requires comparing the expected value of all possible plans that can be taken in the future. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, this preliminary work does provide data that can be useful for conducting a more scientific assessment of the problem. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the need for rescue analgesics led us to speculate that OIH was playing a role. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The results provide new base line data about arch form and dimensions as well as the Bolton ratios, which can be used clinically in diagnosis and treatment planning of patients living in the city of Jeddah. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, minimizing these artifacts and improving the uptake of attenuated segments is likely suitable for better assessing myocardial ischemia and necrosis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This may provide an alternative HLA-independent mechanism to explain the increased permeability in IBS-D. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study suggests several potential mechanisms that account for the interaction between lutein/zeaxanthin and DICER1 rs3742330 regarding CRC risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In total, at least 15 clinical trials and the most recent meta-analyses demonstrated a reduction of contrast-induced renal impairment by prophylactic administration of theophylline, an adenosine antagonist 7,16,25,26. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, we sampled only daily cannabis users who were intending to quit or reduce at some point in the next 3 months. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In their study, Wistar rat pups, with and without medial frontal cortical lesions, were exposed to what was intended to be a “handling” paradigm, from postnatal day four to weaning. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As a first conclusion, our data indicate a correlation between walnut consumption and a shift within the gut microbiome, suggesting that a regular supplementation might offer prebiotic and probiotic benefits by improving the microbiome composition and diversity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | According to Sundell et. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A study of 30 severe enterovirus infections in children from 2012–13, in the south of England did not find any association with EV-D68 [9]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | To describe the coagulation changes in COVID-19 patients, the term CAC (COVID-19-associated coagulopathy) has been introduced 27. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This is the first study that reports CD133+CD44+CD54+ subpopulation of CTCs has a prognostic value in CRC patients with liver metastases, especially those who did not receive surgical treatment for metastases (P < 0.001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The speed of a muscle fiber contraction is closely related to myosin heavy chain (MHC) composition within a muscle [7]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Two of these, PO10-1 and PO10-2, carried blaCTX-M-15 and blaCMY-42, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This rapid relapse rate suggests “front-loaded” treatment with multiple contacts in the first week of a quit attempt (Garvey et al, 2012) should be considered. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results are comparable to previous Australian research, which found 28.0% and 89.0% of drivers consume fewer than the recommended number of serves of fruits and vegetables, respectively, per day.11 Drivers consume more unhealthy food and drink per day than Australian recommendations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Conversely, when considered together with E2 levels, T concentrations in men and women are positive correlates of both mean and pulsatile ACTH secretion, at least during pulsatile cortisol inhibition. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Patient selection, careful preoperative planning and improvement in surgical technique have dramatically reduced our operative fracture rate. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It seemed that EIT was superior to compliance in scanning the “ideal” PEEP, even if the difference about this “ideal” value was slight (8 cm H2O PEEP for the E group vs 10 cm H2O PEEP for the C group). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Processes within the transtheoretical model of change used in the addiction literature may provide insight into increases in tolerance (Prochaska, Norcross, & DiClemente, 1993). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The impact of health care professionals on Turkish citizens is very high. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In three patients, this was the only conspicuous abnormality. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This approach also enabled the identification of specific genes that might be involved in the mechanistic pathways linking menarcheal age with disease. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The renovation of buildings has also been suggested as a source of Q fever in two previous outbreaks (26,39). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The verbal definition of object pictures, however, is dependent not only on access to object representations but also on the integrity of the language network needed to mediate the transcription of non-verbal concepts into a verbal account. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | When examined individually, sex and age both were found to be significant predictors of social anxiety, with females and older adolescent reporting more symptoms. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Because people with SMI utilize public mental health clinics rather than primary care,12 these clinics are their medical home 13. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the present study, approximately 3% of the total variance in BMD was explained by the GRS63 and, considering that ≅60% of the total variance in BMD is genetically determined, this would be equal to the GRS63 explaining ≅5% of the total genetic variance, being of the same magnitude as found in the original GEFOS publication (15). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although experimental work is necessary to elucidate this further, it does suggest that external lesions only manifest themselves during the more advanced stages of the disease, primarily encountered in older individuals. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Postoperative nausea and vomiting (PONV) was lower in group R, whereas itching and urticaria were lower in group N. Opioids and inhalant anesthetics are both known to be major risk factors for PONV,24,25 whereas propofol is known to reduce the degree of PONV26–29. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The difference was not statistically significant in the per-protocol analysis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Consistent with other international studies from both high-income countries and LMICs, the strongest correlate of active commuting and use of public transit was land-use mix [43,60,61,62]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This strategy had inadequate statistical power to detect most true effects of less significant SNPs in a typical GWAS, which includes only a few thousand individuals. |