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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The study found that adult patients attending Oral Health centre at International Medical University, who practised self-medication had stronger beliefs about the benefits of medicines and weaker beliefs in viewing medicines as harmful and overused. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, we will use videofluorography to test hypotheses regarding deglutition behaviors by providing treatments and examining how these treatments relate to function with the ultimate goal of translating these to human trials. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In particular, the differential N400 elicited by the unrelated match reflects the sensitivity to the generally more robust inter-category boundaries whereas the differential N400 elicited by the related mismatch reflects the sensitivity to the more fragile intra-category boundaries where the conflict between activation and inhibition is more pronounced. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | All these encouraging findings support current practices adopted within the Healthcare Surveillance Programs for HCWs and undergraduate healthcare students in several Western countries, confirming their fundamental role for the control of HBV transmission in the healthcare setting. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | First, we demonstrate the dissociation between systemic and local TNF pathway activation in the pathogenesis of podocyte injury. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Macrophages are key angiogenesis effector cells in inflammatory and tumoral angiogenesis [38], and their presence is associated with local secretion of many pro-angiogenic factors [39]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The definition of outbreaks being 10 or fewer SNP differences apart from the nearest neighbor has previously been shown plausible (9) and was thus used in this study. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In our study, HLA-DQ2/8 genotype was not associated with degree of inflammation in SB or rectosigmoid colon mucosa. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Epidemiologic evidence suggests that erythrocyte polymorphisms have arisen in malaria endemic regions to protect an individual from severe malaria [1,2,4]. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Furthermore, aprotinin appears to be the most efficient drug for redLucing postoperative blood loss within 24 hours. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Third, the efficacy of CMRA for cardiac venous assessment specifically in patients with congestive heart failure has not yet been assessed and may prove more challenging. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interestingly, the detachment of MeCP2 following treatment with deacetylating agents is also associated with histone tail reacetylation (Figure 5G), suggesting the presence of a yet unidentified acetylating complex acting in competition with MeCP2/SIN3. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In experiments conducted on animals, allergoids have accordingly induced IgG antibody titres comparable to those from native allergens [16,27]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While TNF causes NF-κB activation in Caco-2 cells and macrophages, the discrepant effect of TNF on ABCA1 expression (upregulated in macrophages and downregulated in Caco-2) suggests that mechanisms other than NF-κB may modulate ABCA1 expression (53). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The study design and the high variability in the observed changes in the microbiome preclude any valid conclusions at this point. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In accordance with previous literature, patients of our study reported expected toxicities of treatment with trabectedin. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | E2 modulates mean, pulsatile, basal, and entropic measures of ACTH secretion under both continuous and pulsatile cortisol feedback. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The effect of pistachios was much stronger than that of almonds and resulted in an increase in potentially beneficial butyrate-producing bacteria in the phylum Firmicutes [42]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is noteworthy that our study found the married or widowed/divorced are independent risk factors for hypertension, contributing 2 and 3 points to the risk score, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As we have reported previously, in our institutional experience, we identified a trend to improve assessment and documentation of the characteristics of pain, as well as intensity and location of pain (Oakes, Anghelescu, Windsor, & Barnhill, 2008). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Due to the power limitations of the insoles, some subjects could not perceive the vibration at its maximum amplitude for particular threshold configurations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, we identify NFATc1 activation as the link between TNF and ABCA1 repression, thus shedding new light on the mechanism of TNF-induced local injury in glomerular diseases as well as other chronic inflammatory conditions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although arterial intima-media density has been correlated with cardiovascular risk factors and carotid plaque echogenicity in elderly adults14, the striking degree of adventitial abnormalities observed in this study have not yet been evaluated in aging and should be the subject of future studies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additionally, there is some preliminary evidence that especially improving contextual skills and positive eating attitudes in weight management interventions are particularly helpful to losing weight [citation]. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is important for nurses to be aware of rescue analgesia strategies, such as PCA analgesia to protect against breakthrough pain on ambulation, end-of-dose failure on controlled-release opioids, or spontaneous pain with no obvious pathology (Chiaretti & Langer, 2005). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | During these periods, drivers are confined to their trucks, and workplace policies often prohibit them from leaving certain pre-defined areas for their own safety.3 Not surprisingly, drivers do not consider transport industry workplaces to be conducive to physical activity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | no discussion section |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | After changes in the structure of our university hospital (a new laparoscopic oncological surgery unit was created), we started performing gastric cancer surgery laparoscopically. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is also possible that age at menarche is an indirect indicator of other macroscopic changes that may impact on DNA methylation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, it is not possible to exclude an unknown carrier of the clone, nor an unregistered travel link for patients P2 to P9, whereas patient P1, with the isolate from 2015 (AMA1167), had traveled to Egypt prior to isolation of AMA1167 (10). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In contrast, mutations at the arginine residues of IV/S4 that cause myotonia and slow the rate of inactivation (31) are presumably because of an effect on the rate of a conformational change rather than on inducing bias. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Considering that ARV treatment is associated with better QoL, the above difference between the two populations might have somehow influenced our results. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In contrast to the findings of LUMA, genome wide methylation in this second dataset did not significantly differ between subjects in different menarcheal age groups. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, endogenous oestrogen exposure is a strong candidate for epigenetic changes since an earlier age at menarche exposes a woman to a greater cumulative amount of endogenous oestrogens over her lifetime, and there have been reports which show that oestrogen impacts on DNA methylation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In diseased cardiovascular tissue and plaque, both animal and human studies have supported duplex ultrasound as a useful tool for detecting tissue pathology with dysregulated extracellular matrix through increased echogenicity. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is important to note that a maximal exercise treadmill test requires the pulmonary system to perform at a peak level; thus, this test allows the assessment of pulmonary function beyond resting levels. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Thus, the reality is that we are only just beginning to answer this question. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The design features of this first confirmatory trial with Hypericum extract in long-term prophylaxis of mild to moderate major depression are in accordance with the demands of current consensus statements and guidance (Center for Drug Evaluation and Research, 1978; Kasper et al, 1997; Committee for Proprietary Medical Products, 2002). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While we recognize that the small sample size of our study means that the findings warrant confirmation in larger cohorts, we conclude that the immunophenotypic landscape in CVID and other PAD comprises a varied and overlapping spectrum in which asymptomatic relatives show an intermediate immunophenotype, supporting the notion of a complex etiological basis of PAD. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this study, age at menarche was negatively associated with LUMA genome wide methylation in a statistically significant manner. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Previous studies showed inconsistent results for the association between ARV treatment and QoL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | AKT participates in cellular survival and protein\[citation\]\. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Nonetheless, previous studies provided data that daily salt intake of local population is about 12.4–16.1 g [30,31]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In fact, the host response and the immune mechanisms require fine balances between pro- and anti-inflammatory components and between recruitment and death of immunocompetent cells, involving lymphocytes and monocytes. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The results of the current study indicate that there are unique associations of emotion regulation, dispositional mindfulness, and social support with adolescents’ social anxiety; therefore improving these constructs may be helpful for adolescents who are at risk of, or are suffering from, higher symptoms of social anxiety. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Differences between our findings and those of other research groups may have been due to technical differences in analysis methods or differences in laboratory technique. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this view, this region may harbor susceptibility loci for clinical features of AD, or its risk factors, but is protective for early change in memory. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The majority of patients attending public sector services are required to pay for medicines from private vendors due to depletion of essential drug stocks, and many experience pressure to pay unofficial fees to members of staff [28, 42–44]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The analysis of CD4 cell count and QoL was suggestive of an association. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Sometimes, pacemaker remains are found. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, a possible contribution of macrophages to significant angiogenin synthesis in specific articular diseases remains to be demonstrated. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In animal models, the ratio of Bacteroidetes and Firmicutes is altered in response to dietary changes [18]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Those with normal IMT had the same increased echogenicity as those with widened IMT within both the intima-media and within plaques. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | More specifically it was shown that oestrogen receptor (ER) positive breast tumour tissues have differential methylation at several CpG loci compared to ER negative tumours [24], [31] and oestrogen induced breast tumours have differential DNA methylation patterns in ACI rat mammary gland tissue [32]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Baumgartner et al. have reported a 98.9% survival rate in their series of 533 primary Alloclassic THRs at 6 to 7 years [1]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, we analyzed performance not only in terms of mean group differences in raw scores but also using normative data from non-TBI persons to determine the degree of impairment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study showed that individuals younger than 40 years of age and those with lower education level are at higher risk of having poorer QoL and health perception, while individuals with higher CD4 levels and those receiving ARV treatment tend to have better QoL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The slowing of reaction times during trials where the correct choice and the foil both belonged to the same category offered a measure of the magnitude of taxonomic interference. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The overall findings shows that mean social anxiety score among Nepalese adolescent students in the current study were 2.31. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, we instituted hemoconcentration and postoperative reinfusion of blood drained from the operative field and the extracorporeal circuit. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Spirometry is primarily performed at rest and is largely effort dependent. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The tooth size discrepancy in Class III cases was the most prevalent. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The prevalence of severe complications and paucity of systematic surveillance data reinforce the importance of continuing and improving surveillance in this area and implementing recent enterovirus diagnostic guidance for systematic surveillance of non-polio enterovirus types [5]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Understanding the intersections and distinctions between HGPS and normal aging can inform both fields of study, and help us to interpret the clinical influence that progerin may have after a lifetime of low level accumulation in aging4, 26, 27, versus its intense production in children with HGPS. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It was shown that these elements shorten LOS, and their simultaneous use has a synergistic effect. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The psychological nature of such cached values can be related to either Pavlovian (as used in [12]) or instrumental (as used in [11]) processes in the brain, depending on whether cached values are coded for state or for state-action pairs, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this study, the life satisfaction ratings of patients who reported a very central religious meaning system were not negatively influenced by higher levels of pain. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Following discharge from hospital, prolonged pharmacological VTE prophylaxis in the ambulatory setting is reasonable in patients with persistent immobility, high inflammatory activity, and/or additional risk factors (as mentioned above). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We had anticipated that the inclusion of sensitive neuropsychological measures as secondary outcomes in this clinical trial would demonstrate a benefit in specific cognitive domains such as memory and executive functioning beyond the more global abilities measured by the GOSE. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The analysis per cycle performed in patients treated with the monotherapy regimen in our study showed grade 3 elevations of AST and ALT in 12% and 20% of cycles, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | 18 and 19) but not others (e.g., refs. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Such syndromes respond incompletely to opioids (Fields, 1988; Portenoy, Foley, & Inturrisi, 1990; Rowbotham et al., 2003). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These previous findings enhance the biological plausibility that this SNP in STAT4 may play an important role in the liver fibrosis progression, although the molecular mechanism remains uncertain and further functional studies are required. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings may be further validated by longer term follow-up and cognitive outcome assessments that are not possible at age 2 years. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this study, we examined the role of inflammatory mediators and apoptotic mechanisms in the pathophysiology of CRS Type 5. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Six months after the operation we found no significant differences in the results of the self-assessment questionnaires between groups. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The studies by Bock and colleagues indicate that only short durations of maternal separation stress are necessary to induce dendritic and spine alterations in sensory cortex (Bock et al, 2005). |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since modern multimodal care involves all medical staff members (surgeons, anesthetists, nurses, dieticians, physiotherapists), the whole team should establish compliance with the protocol. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Persistent, continuous pain is best managed with long-acting opioids. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our results are particularly concordant with a study on post-stroke patients that attributed a specific and critical role of the left anterior temporal lobe in mediating fine-grained taxonomic distinctions during the retrieval of object names and which showed that this role was not dependent on amodal pre-lexical conceptualization impairments (Schwartz et al, 2009; Walker et al, 2011). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The major strengths of our study are the prospective nature and the longitudinal design. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The accuracy and precision of the calibrated CDI estimates, gas or ABL calibration, for pH, pCO2, and pO2 were not significantly different from the ABL values, and thus the calibrated CDI can be a valuable tool for the perfusionist in maintaining a stable and physiologically correct acid-base balance during CPB. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study has several limitations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Two case reports implicate straw: a physician who contracted Q fever after clearing out straw and rubble from his new moorland home (26) and a businessman who was cleaning out a barn that had been used for keeping livestock 10 years previously but had not been properly cleaned since (24). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interestingly, craving failed to increase in about half of the prior cannabis abstinence studies (Allsop et al, 2012), and this also often occurred in tobacco abstinence studies (Shiffman, West, & Gilbert, 2004). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, some positive individuals were subsequently recorded as being negative for cutaneous lesions, suggesting that lesions may be a transient stage in advanced infections. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the patient in the tranexa.mic acid group who required reoperation to establish hemiiostasis, no surgical bleeding w.as found and only clots were removed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, late menarche and early menopause decrease the risk of developing breast cancer (Key et al, 2001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since knockdown of ABCA1 did not lead to podocyte injury in vitro (Figure 5) and in vivo (Supplemental Figure 14), it is likely that a second hit is required to cause podocyte injury. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This property, which was also observed for the sitting position here, may likely be explained by lower amplitudes of breathing-related diaphragmatic motion, as already documented for upright versus supine positions in previous MRI and ultrasound studies (25,26). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There were some exceptions with 2 individuals being positive for 6 months. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Today, most pacemakers are driven by the lithium/iodine-PVP energy source. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The difference was, however, less than 1 point. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The biker position was additionally associated with a trend toward a lower rate of anteroseptal and apical defects, as compared with the supine position, together with a higher normal segmental uptake in the proximal and median portion of the anterior wall (segments 1 and 7 in Fig. 2). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our response criterion for acute treatment, which also serves as an eligibility criterion for continuation treatment, combines well-defined clinical improvement and a halving of the initial HAMD total score. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the Western region of Saudi Arabia, very few studies were conducted to assess dental arch forms and tooth mass ratio of lower to upper dentitions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Unlike the previous studies, the sample of the present study was collected from different private practices in Jeddah, Saudi Arabia to be representative for the patients seeking treatment in that city. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Similarly, patients presenting at oral health outreach programs were recruited in the study conducted by Simon et al, [10]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Figure 4 highlights the quantitative power of analytic morphomics over standard measures of height, weight, and BMI when evaluating like-sized individuals with different body compositions. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our results suggest that populations bearing a heavy burden of health disadvantage may require enhancing intervention dose. |